locus-tag	class	description
EXW30_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW30_00010	COG0592	DNA-directed DNA polymerase activity
EXW30_00015	COG2501	S4 domain
EXW30_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW30_00025	COG0187	DNA topoisomerase II activity
EXW30_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW30_00065	COG0516	GMP reductase activity
EXW30_00065	COG0517	IMP dehydrogenase activity
EXW30_00070	COG1686	Belongs to the peptidase S11 family
EXW30_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW30_00100	COG1428	Deoxynucleoside kinase
EXW30_00105	COG1428	Deoxynucleoside kinase
EXW30_00110	COG1335	isochorismatase
EXW30_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW30_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW30_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW30_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW30_00180	COG1982	Orn Lys Arg decarboxylase major
EXW30_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW30_00190	COG0470	DNA polymerase III
EXW30_00195	COG1774	PSP1 C-terminal conserved region
EXW30_00200	COG4467	Involved in initiation control of chromosome replication
EXW30_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW30_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW30_00220	COG2002	toxin-antitoxin pair type II binding
EXW30_00230	COG0084	hydrolase, TatD family'
EXW30_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW30_00250	COG4466	Protein conserved in bacteria
EXW30_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW30_00270	COG0251	oxidation-reduction process
EXW30_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW30_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW30_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW30_00305	COG2002	toxin-antitoxin pair type II binding
EXW30_00310	COG2244	polysaccharide biosynthetic process
EXW30_00315	COG3956	TIGRFAM MazG family protein
EXW30_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW30_00340	COG1098	S1 RNA binding domain
EXW30_00355	COG2208	phosphoserine phosphatase activity
EXW30_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW30_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW30_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW30_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW30_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW30_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW30_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW30_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW30_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW30_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW30_00420	COG1396	sequence-specific DNA binding
EXW30_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW30_00520	COG3880	PFAM UvrB UvrC protein
EXW30_00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW30_00530	COG0542	response to heat
EXW30_00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW30_00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW30_00545	COG4956	integral membrane protein (PIN domain superfamily)
EXW30_00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW30_00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW30_00565	COG1045	serine acetyltransferase
EXW30_00570	COG0215	cysteine-tRNA ligase activity
EXW30_00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW30_00585	COG3688	RNA-binding protein containing a PIN domain
EXW30_00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW30_00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW30_00605	COG0250	Participates in transcription elongation, termination and antitermination
EXW30_00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW30_00615	COG0081	regulation of translation
EXW30_00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW30_00625	COG0222	ribosome binding
EXW30_00630	COG2813	Specifically methylates the guanine in position
EXW30_00635	COG0085	RNA polymerase activity
EXW30_00640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW30_00645	COG1358	cellular component organization or biogenesis
EXW30_00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW30_00655	COG0049	tRNA binding
EXW30_00660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW30_00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW30_00670	COG0051	transcription antitermination factor activity, RNA binding
EXW30_00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW30_00680	COG0088	Forms part of the polypeptide exit tunnel
EXW30_00685	COG0089	rRNA binding
EXW30_00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW30_00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW30_00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW30_00710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EXW30_00715	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW30_00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW30_00725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EXW30_00730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW30_00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW30_00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW30_00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW30_00765	COG1841	ribosomal large subunit assembly
EXW30_00770	COG0200	Binds to the 23S rRNA
EXW30_00775	COG0201	protein transport
EXW30_00780	COG0563	adenylate kinase activity
EXW30_00785	COG0024	Methionine aminopeptidase
EXW30_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW30_00800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW30_00805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW30_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW30_00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW30_00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW30_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW30_00860	COG0489	protein tyrosine kinase activity
EXW30_00870	COG2194	sulfuric ester hydrolase activity
EXW30_00875	COG0726	polysaccharide deacetylase
EXW30_00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW30_00960	COG4856	YbbR-like protein
EXW30_01005	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_01010	COG2011	ABC-type metal ion transport system permease component
EXW30_01020	COG1464	Belongs to the NlpA lipoprotein family
EXW30_01025	COG0604	alcohol dehydrogenase
EXW30_01035	COG0277	FAD linked oxidase domain protein
EXW30_01040	COG2271	Major facilitator Superfamily
EXW30_01050	COG2814	Major facilitator Superfamily
EXW30_01070	COG0601	transmembrane transport
EXW30_01075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW30_01080	COG0444	Belongs to the ABC transporter superfamily
EXW30_01085	COG4608	Belongs to the ABC transporter superfamily
EXW30_01090	COG4166	transmembrane transport
EXW30_01100	COG2207	Transcriptional regulator
EXW30_01115	COG4166	transmembrane transport
EXW30_01120	COG4166	transmembrane transport
EXW30_01125	COG0656	L-ascorbic acid biosynthetic process
EXW30_01130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW30_01140	COG4149	molybdate abc transporter
EXW30_01145	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW30_01150	COG1910	domain protein
EXW30_01165	COG0697	spore germination
EXW30_01180	COG0204	Acyl-transferase
EXW30_01190	COG1609	Transcriptional regulator
EXW30_01200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW30_01215	COG5298	Protein conserved in bacteria
EXW30_01240	COG0488	(ABC) transporter
EXW30_01255	COG0747	negative chemotaxis
EXW30_01265	COG0601	transmembrane transport
EXW30_01270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW30_01275	COG0444	Belongs to the ABC transporter superfamily
EXW30_01280	COG4608	Belongs to the ABC transporter superfamily
EXW30_01285	COG0561	phosphatase activity
EXW30_01315	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW30_01320	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW30_01330	COG0531	amino acid
EXW30_01335	COG2814	Major facilitator Superfamily
EXW30_01345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW30_01355	COG4294	response to UV
EXW30_01360	COG0705	Rhomboid family
EXW30_01365	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW30_01370	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW30_01375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW30_01380	COG0864	Transcriptional regulator
EXW30_01385	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW30_01390	COG2183	response to ionizing radiation
EXW30_01490	COG0802	atpase or kinase
EXW30_01495	COG1214	PFAM Peptidase M22, glycoprotease
EXW30_01500	COG0456	acetyltransferase
EXW30_01510	COG0488	(ABC) transporter
EXW30_01515	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW30_01525	COG1266	CAAX protease self-immunity
EXW30_01530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW30_01535	COG0459	protein refolding
EXW30_01540	COG0519	Catalyzes the synthesis of GMP from XMP
EXW30_01540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW30_01545	COG2252	PERMEase
EXW30_01555	COG5002	protein histidine kinase activity
EXW30_01580	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW30_01645	COG2205	protein histidine kinase activity
EXW30_01650	COG0745	RESPONSE REGULATOR receiver
EXW30_01670	COG0697	spore germination
EXW30_01695	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW30_01700	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW30_01705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW30_01715	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW30_01720	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW30_01725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW30_01730	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW30_01735	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW30_01740	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW30_01745	COG0138	bifunctional purine biosynthesis protein purh
EXW30_01750	COG0151	Belongs to the GarS family
EXW30_01770	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW30_01775	COG0210	DNA helicase
EXW30_01780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW30_01785	COG4851	CamS sex pheromone cAM373 precursor
EXW30_01795	COG1012	belongs to the aldehyde dehydrogenase family
EXW30_01805	COG1335	isochorismatase
EXW30_01820	COG0003	Pfam Anion-transporting ATPase
EXW30_01825	COG1846	Transcriptional regulator
EXW30_01830	COG4682	membrane
EXW30_01840	COG0154	amidase activity
EXW30_01845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW30_01850	COG1597	lipid kinase activity
EXW30_01865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW30_01880	COG1012	belongs to the aldehyde dehydrogenase family
EXW30_01885	COG2076	Multidrug Resistance protein
EXW30_01895	COG2309	aminopeptidase activity
EXW30_01910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW30_01920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW30_01945	COG4807	Protein conserved in bacteria
EXW30_01975	COG1757	Na H antiporter
EXW30_01980	COG1473	amidohydrolase
EXW30_02000	COG0450	alkyl hydroperoxide reductase
EXW30_02010	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW30_02020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW30_02025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW30_02030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW30_02040	COG0492	ferredoxin-NADP+ reductase activity
EXW30_02055	COG0166	Belongs to the GPI family
EXW30_02080	COG5002	protein histidine kinase activity
EXW30_02095	COG3541	Predicted nucleotidyltransferase
EXW30_02100	COG0723	plastoquinol--plastocyanin reductase activity
EXW30_02100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW30_02110	COG0765	amino acid transport
EXW30_02115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW30_02120	COG1126	abc transporter atp-binding protein
EXW30_02125	COG0840	transmembrane signaling receptor activity
EXW30_02130	COG0277	FAD linked oxidase domain protein
EXW30_02135	COG0366	Alpha amylase catalytic
EXW30_02140	COG1263	PTS System
EXW30_02140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW30_02140	COG2190	(PTS) system
EXW30_02160	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW30_02165	COG0352	thiamine-phosphate diphosphorylase activity
EXW30_02170	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW30_02190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW30_02200	COG1116	anion transmembrane transporter activity
EXW30_02205	COG0488	(ABC) transporter
EXW30_02230	COG2270	Major facilitator Superfamily
EXW30_02260	COG2310	stress, protein
EXW30_02265	COG2310	stress, protein
EXW30_02270	COG2310	stress, protein
EXW30_02275	COG0861	Integral membrane protein TerC family
EXW30_02285	COG3853	Toxic anion resistance protein (TelA)
EXW30_02295	COG4840	Belongs to the UPF0435 family
EXW30_02300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW30_02310	COG1295	ribonuclease BN
EXW30_02315	COG2217	Heavy metal translocating P-type atpase
EXW30_02320	COG0697	spore germination
EXW30_02345	COG0586	Pfam SNARE associated Golgi protein
EXW30_02360	COG3871	stress protein (general stress protein 26)
EXW30_02365	COG0387	Pfam Sodium calcium exchanger
EXW30_02375	COG0535	radical SAM domain protein
EXW30_02395	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW30_02415	COG3829	transcription factor binding
EXW30_02425	COG0833	amino acid
EXW30_02435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW30_02460	COG1263	PTS System
EXW30_02460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW30_02465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW30_02485	COG1215	transferase activity, transferring glycosyl groups
EXW30_02495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW30_02495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW30_02505	COG3344	reverse transcriptase
EXW30_02520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW30_02525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW30_02540	COG1228	amidohydrolase
EXW30_02545	COG1090	epimerase
EXW30_02550	COG2137	regulation of response to DNA damage stimulus
EXW30_02575	COG1988	membrane-bound metal-dependent
EXW30_02580	COG1194	a g-specific adenine glycosylase
EXW30_02595	COG3557	Belongs to the UPF0374 family
EXW30_02600	COG1132	(ABC) transporter
EXW30_02605	COG4129	membrane
EXW30_02615	COG0067	glutamate synthase
EXW30_02615	COG0069	glutamate synthase activity
EXW30_02615	COG0070	glutamate synthase
EXW30_02620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW30_02625	COG4555	ABC transporter
EXW30_02645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW30_02650	COG0735	belongs to the Fur family
EXW30_02765	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW30_02770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW30_02790	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW30_02800	COG2766	serine protein kinase
EXW30_02805	COG2718	Belongs to the UPF0229 family
EXW30_02820	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW30_02825	COG2268	Band 7 protein
EXW30_02830	COG3290	protein histidine kinase activity
EXW30_02835	COG4565	transcriptional regulatory protein
EXW30_02840	COG2851	Citrate transporter
EXW30_02860	COG0745	RESPONSE REGULATOR receiver
EXW30_02865	COG5002	protein histidine kinase activity
EXW30_02875	COG4990	cell redox homeostasis
EXW30_02885	COG3290	protein histidine kinase activity
EXW30_02890	COG4565	transcriptional regulatory protein
EXW30_02895	COG3493	citrate carrier protein
EXW30_02900	COG0281	malic enzyme
EXW30_02910	COG0697	spore germination
EXW30_02915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW30_02925	COG5002	protein histidine kinase activity
EXW30_02930	COG0745	RESPONSE REGULATOR receiver
EXW30_02935	COG0456	acetyltransferase
EXW30_02940	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW30_02945	COG3383	formate dehydrogenase (NAD+) activity
EXW30_02950	COG2427	Protein of unknown function (DUF1641)
EXW30_02965	COG0531	amino acid
EXW30_02975	COG0640	Transcriptional regulator
EXW30_02980	COG2217	Heavy metal translocating P-type atpase
EXW30_02985	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW30_02995	COG3227	Zinc metalloprotease (Elastase)
EXW30_03015	COG2720	vancomycin resistance protein
EXW30_03020	COG1316	TRANSCRIPTIONal
EXW30_03025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW30_03030	COG0346	lactoylglutathione lyase activity
EXW30_03035	COG1253	flavin adenine dinucleotide binding
EXW30_03040	COG1027	Aspartate ammonia-lyase
EXW30_03045	COG1620	l-lactate permease
EXW30_03050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW30_03070	COG3344	reverse transcriptase
EXW30_03080	COG3104	oligopeptide transport
EXW30_03085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW30_03090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW30_03095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW30_03110	COG0156	8-amino-7-oxononanoate synthase activity
EXW30_03115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW30_03125	COG4548	von Willebrand factor, type A
EXW30_03130	COG0714	Associated with various cellular activities
EXW30_03155	COG0531	amino acid
EXW30_03160	COG2188	Transcriptional regulator
EXW30_03165	COG1263	PTS System
EXW30_03165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW30_03170	COG0366	Alpha amylase catalytic
EXW30_03190	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW30_03195	COG1115	amino acid carrier protein
EXW30_03200	COG1126	abc transporter atp-binding protein
EXW30_03205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW30_03210	COG0765	amino acid transport
EXW30_03215	COG0765	amino acid transport
EXW30_03220	COG0833	amino acid
EXW30_03235	COG2378	regulation of single-species biofilm formation
EXW30_03240	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW30_03245	COG5002	protein histidine kinase activity
EXW30_03260	COG0659	secondary active sulfate transmembrane transporter activity
EXW30_03285	COG0601	transmembrane transport
EXW30_03290	COG4608	Belongs to the ABC transporter superfamily
EXW30_03300	COG2271	Major facilitator Superfamily
EXW30_03305	COG1846	Transcriptional regulator
EXW30_03310	COG0477	Major facilitator Superfamily
EXW30_03315	COG1609	Transcriptional regulator
EXW30_03320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW30_03325	COG1869	D-ribose catabolic process
EXW30_03335	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW30_03340	COG1879	ABC-type sugar transport system periplasmic component
EXW30_03370	COG1063	alcohol dehydrogenase
EXW30_03415	COG0840	transmembrane signaling receptor activity
EXW30_03420	COG3584	3D domain protein
EXW30_03420	COG3583	domain protein
EXW30_03425	COG1476	TRANSCRIPTIONal
EXW30_03445	COG3104	oligopeptide transport
EXW30_03450	COG1114	Component of the transport system for branched-chain amino acids
EXW30_03465	COG1113	amino acid transport
EXW30_03470	COG2252	PERMEase
EXW30_03485	COG2153	protein acetylation
EXW30_03495	COG0475	glutathione-regulated potassium exporter activity
EXW30_03495	COG0569	domain protein
EXW30_03505	COG1845	cytochrome c oxidase, subunit III
EXW30_03510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW30_03515	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EXW30_03520	COG0833	amino acid
EXW30_03525	COG4990	cell redox homeostasis
EXW30_03540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW30_03545	COG0697	spore germination
EXW30_03550	COG0531	amino acid
EXW30_03560	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW30_03565	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW30_03575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW30_03580	COG0573	inorganic phosphate transmembrane transporter activity
EXW30_03585	COG0581	inorganic phosphate transmembrane transporter activity
EXW30_03595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW30_03640	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW30_03720	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW30_03735	COG4991	sh3 domain protein
EXW30_03735	COG3103	Sh3 type 3 domain protein
EXW30_03735	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW30_03740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW30_03745	COG1116	anion transmembrane transporter activity
EXW30_03750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW30_03755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW30_03760	COG0352	thiamine-phosphate diphosphorylase activity
EXW30_03765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW30_03770	COG2104	thiamine diphosphate biosynthetic process
EXW30_03775	COG2022	thiamine diphosphate biosynthetic process
EXW30_03780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW30_03785	COG0351	phosphomethylpyrimidine kinase
EXW30_03815	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW30_03820	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW30_03825	COG2205	protein histidine kinase activity
EXW30_03850	COG1136	(ABC) transporter
EXW30_03860	COG2252	PERMEase
EXW30_03865	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_03925	COG0778	Nitroreductase
EXW30_03930	COG2719	SpoVR family
EXW30_03955	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW30_03960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW30_03970	COG1937	Protein conserved in bacteria
EXW30_03975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW30_03975	COG0425	Belongs to the sulfur carrier protein TusA family
EXW30_03980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW30_03980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW30_03985	COG0425	Belongs to the sulfur carrier protein TusA family
EXW30_03990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW30_03995	COG2210	Belongs to the sulfur carrier protein TusA family
EXW30_04000	COG0730	response to heat
EXW30_04010	COG1316	TRANSCRIPTIONal
EXW30_04015	COG0604	alcohol dehydrogenase
EXW30_04020	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW30_04030	COG2814	Major facilitator Superfamily
EXW30_04045	COG3711	transcriptional antiterminator
EXW30_04045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW30_04050	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW30_04055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW30_04075	COG1388	LysM domain
EXW30_04075	COG3584	3D domain protein
EXW30_04080	COG0577	efflux transmembrane transporter activity
EXW30_04085	COG1136	(ABC) transporter
EXW30_04095	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW30_04110	COG1114	Component of the transport system for branched-chain amino acids
EXW30_04115	COG3546	catalase activity
EXW30_04145	COG0586	Pfam SNARE associated Golgi protein
EXW30_04180	COG0531	amino acid
EXW30_04185	COG0475	glutathione-regulated potassium exporter activity
EXW30_04205	COG1263	PTS System
EXW30_04205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW30_04215	COG2259	Doxx family
EXW30_04250	COG0531	amino acid
EXW30_04260	COG0351	phosphomethylpyrimidine kinase
EXW30_04265	COG1757	Na H antiporter
EXW30_04270	COG4496	protein, YerC YecD
EXW30_04285	COG1522	sequence-specific DNA binding
EXW30_04295	COG0300	oxidoreductase activity
EXW30_04300	COG0789	Transcriptional regulator
EXW30_04310	COG2076	Multidrug Resistance protein
EXW30_04315	COG1309	transcriptional regulator
EXW30_04325	COG2814	Major facilitator Superfamily
EXW30_04330	COG1733	regulation of RNA biosynthetic process
EXW30_04340	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW30_04365	COG4473	ABC transporter
EXW30_04370	COG0531	amino acid
EXW30_04375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EXW30_04380	COG1012	belongs to the aldehyde dehydrogenase family
EXW30_04395	COG1132	(ABC) transporter
EXW30_04400	COG1132	(ABC) transporter
EXW30_04405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW30_04410	COG0765	amino acid transport
EXW30_04415	COG1126	abc transporter atp-binding protein
EXW30_04430	COG0189	ligase activity
EXW30_04440	COG4399	Belongs to the UPF0754 family
EXW30_04445	COG3679	Belongs to the UPF0342 family
EXW30_04460	COG0028	Belongs to the TPP enzyme family
EXW30_04465	COG3527	Alpha-acetolactate decarboxylase
EXW30_04470	COG0463	Glycosyl transferase, family 2
EXW30_04475	COG1216	Glycosyl transferase, family 2
EXW30_04480	COG2094	Belongs to the DNA glycosylase MPG family
EXW30_04485	COG0561	phosphatase activity
EXW30_04490	COG3409	Peptidoglycan-binding domain 1 protein
EXW30_04490	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW30_04495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW30_04500	COG0318	PFAM AMP-dependent synthetase and ligase
EXW30_04510	COG0586	Pfam SNARE associated Golgi protein
EXW30_04520	COG0789	Transcriptional regulator
EXW30_04520	COG4978	Transcriptional regulator
EXW30_04530	COG0659	secondary active sulfate transmembrane transporter activity
EXW30_04535	COG2244	polysaccharide biosynthetic process
EXW30_04555	COG1024	Enoyl-CoA hydratase
EXW30_04570	COG1363	Peptidase, m42
EXW30_04590	COG2318	DinB family
EXW30_04600	COG1113	amino acid transport
EXW30_04605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW30_04625	COG0579	oxidoreductase
EXW30_04635	COG3290	protein histidine kinase activity
EXW30_04635	COG3829	transcription factor binding
EXW30_04645	COG1301	dicarboxylic acid transport
EXW30_04705	COG0477	Major facilitator Superfamily
EXW30_04710	COG3290	protein histidine kinase activity
EXW30_04715	COG4565	transcriptional regulatory protein
EXW30_04720	COG3181	Tripartite tricarboxylate transporter family receptor
EXW30_04755	COG0305	Participates in initiation and elongation during chromosome replication
EXW30_04780	COG1842	Phage shock protein A
EXW30_04790	COG0477	Major facilitator Superfamily
EXW30_04845	COG1183	phosphatidylcholine synthase activity
EXW30_04860	COG2814	Major facilitator Superfamily
EXW30_04865	COG0640	Transcriptional regulator
EXW30_04890	COG2376	Dihydroxyacetone kinase
EXW30_04910	COG2376	Dihydroxyacetone kinase
EXW30_04935	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW30_04935	COG2755	lipolytic protein G-D-S-L family
EXW30_04950	COG2720	vancomycin resistance protein
EXW30_04960	COG1335	isochorismatase
EXW30_04970	COG2373	Large extracellular alpha-helical protein
EXW30_05005	COG0076	glutamate decarboxylase activity
EXW30_05030	COG4585	Histidine kinase
EXW30_05035	COG2197	response regulator
EXW30_05060	COG0420	3'-5' exonuclease activity
EXW30_05065	COG4717	serine-type aminopeptidase activity
EXW30_05070	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW30_05080	COG0346	lactoylglutathione lyase activity
EXW30_05085	COG2267	carboxylic ester hydrolase activity
EXW30_05095	COG2140	Oxalate decarboxylase
EXW30_05100	COG3620	sequence-specific DNA binding
EXW30_05105	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW30_05110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW30_05115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW30_05120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW30_05130	COG1595	DNA-templated transcription, initiation
EXW30_05145	COG3973	AAA domain
EXW30_05175	COG0537	adenosine 5'-monophosphoramidase activity
EXW30_05180	COG1131	(ABC) transporter
EXW30_05185	COG4473	ABC transporter
EXW30_05235	COG0247	lactate metabolic process
EXW30_05240	COG1139	Iron-sulfur cluster binding protein
EXW30_05245	COG1556	Lactate utilization protein
EXW30_05255	COG1653	transport
EXW30_05290	COG1309	transcriptional regulator
EXW30_05295	COG3402	PFAM membrane-flanked domain
EXW30_05300	COG3428	Bacterial PH domain
EXW30_05340	COG3402	PFAM membrane-flanked domain
EXW30_05345	COG3428	Bacterial PH domain
EXW30_05350	COG2329	Antibiotic biosynthesis monooxygenase
EXW30_05355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW30_05360	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW30_05365	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW30_05370	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW30_05390	COG1309	transcriptional regulator
EXW30_05395	COG1511	domain protein
EXW30_05400	COG1216	Glycosyl transferase, family 2
EXW30_05400	COG0438	transferase activity, transferring glycosyl groups
EXW30_05420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW30_05435	COG2378	regulation of single-species biofilm formation
EXW30_05440	COG1609	Transcriptional regulator
EXW30_05450	COG1234	tRNA 3'-trailer cleavage
EXW30_05455	COG0095	Lipoate-protein ligase
EXW30_05475	COG0318	PFAM AMP-dependent synthetase and ligase
EXW30_05490	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW30_05495	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW30_05500	COG4208	sulfate ABC transporter
EXW30_05550	COG1408	metallophosphoesterase
EXW30_05555	COG1078	dGTPase activity
EXW30_05595	COG1595	DNA-templated transcription, initiation
EXW30_05605	COG2207	Transcriptional regulator
EXW30_05605	COG3708	Transcriptional regulator
EXW30_05610	COG2205	protein histidine kinase activity
EXW30_05615	COG0745	RESPONSE REGULATOR receiver
EXW30_05640	COG0501	Belongs to the peptidase M48B family
EXW30_05645	COG0697	spore germination
EXW30_05650	COG2373	Large extracellular alpha-helical protein
EXW30_05655	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW30_05660	COG2224	Isocitrate lyase
EXW30_05670	COG1278	Cold shock
EXW30_05685	COG4903	ComK protein
EXW30_05695	COG0398	Pfam SNARE associated Golgi protein
EXW30_05705	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW30_05710	COG1074	ATP-dependent DNA helicase activity
EXW30_05760	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW30_05785	COG0367	asparagine synthase
EXW30_05795	COG0753	catalase activity
EXW30_05800	COG0004	ammonium transporteR
EXW30_05810	COG1666	GTP binding
EXW30_05815	COG2996	Protein conserved in bacteria
EXW30_05830	COG1329	Transcriptional regulator
EXW30_05865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW30_05875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW30_05890	COG0561	phosphatase activity
EXW30_05910	COG2267	carboxylic ester hydrolase activity
EXW30_05925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW30_05930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW30_05935	COG5504	Zn-dependent protease
EXW30_05945	COG0180	Tryptophanyl-tRNA synthetase
EXW30_05960	COG4166	transmembrane transport
EXW30_05965	COG0601	transmembrane transport
EXW30_05970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW30_05975	COG0444	Belongs to the ABC transporter superfamily
EXW30_05980	COG4608	Belongs to the ABC transporter superfamily
EXW30_05985	COG0534	Mate efflux family protein
EXW30_05990	COG4166	transmembrane transport
EXW30_06010	COG0861	Integral membrane protein TerC family
EXW30_06015	COG4862	establishment of competence for transformation
EXW30_06020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW30_06030	COG1164	Oligoendopeptidase f
EXW30_06040	COG2346	COG2346, Truncated hemoglobins
EXW30_06045	COG4116	CYTH
EXW30_06055	COG2357	RelA SpoT domain protein
EXW30_06065	COG0564	pseudouridine synthase activity
EXW30_06075	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW30_06080	COG0772	Belongs to the SEDS family
EXW30_06090	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW30_06105	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW30_06150	COG2153	protein acetylation
EXW30_06155	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW30_06160	COG2382	esterase
EXW30_06185	COG5492	domain, Protein
EXW30_06190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW30_06210	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW30_06210	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW30_06215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW30_06220	COG0134	indole-3-glycerol-phosphate synthase activity
EXW30_06225	COG0135	phosphoribosylanthranilate isomerase activity
EXW30_06235	COG0159	tryptophan synthase activity
EXW30_06245	COG1620	l-lactate permease
EXW30_06250	COG5634	Uncharacterized conserved protein (DUF2278)
EXW30_06290	COG2226	methyltransferase
EXW30_06310	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW30_06315	COG0567	Dehydrogenase, E1 component
EXW30_06320	COG1476	TRANSCRIPTIONal
EXW30_06365	COG1686	Belongs to the peptidase S11 family
EXW30_06370	COG0681	Belongs to the peptidase S26 family
EXW30_06405	COG1012	belongs to the aldehyde dehydrogenase family
EXW30_06415	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW30_06420	COG1177	transmembrane transport
EXW30_06425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW30_06435	COG2409	Drug exporters of the RND superfamily
EXW30_06445	COG0564	pseudouridine synthase activity
EXW30_06455	COG2340	Cysteine-rich secretory protein family
EXW30_06460	COG0247	lactate metabolic process
EXW30_06465	COG0277	FAD linked oxidase domain protein
EXW30_06470	COG3835	regulator
EXW30_06480	COG0745	RESPONSE REGULATOR receiver
EXW30_06485	COG3850	Histidine kinase
EXW30_06485	COG5002	protein histidine kinase activity
EXW30_06490	COG2186	Transcriptional regulator
EXW30_06505	COG1556	Lactate utilization protein
EXW30_06510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW30_06525	COG0583	DNA-binding transcription factor activity
EXW30_06530	COG2116	formate transmembrane transporter activity
EXW30_06535	COG0861	Integral membrane protein TerC family
EXW30_06540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW30_06550	COG2030	dehydratase
EXW30_06570	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_06575	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW30_06585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW30_06600	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW30_06605	COG3842	ATPase activity
EXW30_06615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW30_06620	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW30_06630	COG1349	DNA-binding transcription factor activity
EXW30_06640	COG0235	Class ii aldolase
EXW30_06650	COG2861	carbohydrate metabolic process
EXW30_06660	COG3852	Histidine kinase
EXW30_06665	COG1846	Transcriptional regulator
EXW30_06675	COG2318	DinB family
EXW30_06680	COG5002	protein histidine kinase activity
EXW30_06690	COG0720	synthase
EXW30_06700	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW30_06705	COG4873	Protein conserved in bacteria
EXW30_06715	COG0456	acetyltransferase
EXW30_06735	COG1780	Probably involved in ribonucleotide reductase function
EXW30_06750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW30_06755	COG0531	amino acid
EXW30_06775	COG2204	response regulator
EXW30_06780	COG1012	belongs to the aldehyde dehydrogenase family
EXW30_06790	COG1725	Transcriptional regulator
EXW30_06795	COG1131	(ABC) transporter
EXW30_06805	COG1131	(ABC) transporter
EXW30_06810	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW30_06815	COG1266	CAAX protease self-immunity
EXW30_06825	COG1522	sequence-specific DNA binding
EXW30_06835	COG1335	isochorismatase
EXW30_06845	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW30_06850	COG2070	2-Nitropropane dioxygenase
EXW30_06855	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW30_06860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW30_06865	COG1696	Membrane protein involved in D-alanine export
EXW30_06885	COG0716	FMN binding
EXW30_06910	COG0534	Mate efflux family protein
EXW30_06930	COG1846	Transcriptional regulator
EXW30_06945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW30_06955	COG3874	Sporulation protein YtfJ
EXW30_06975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW30_06980	COG0028	Belongs to the TPP enzyme family
EXW30_06985	COG0440	acetolactate synthase activity
EXW30_06995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW30_07005	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW30_07015	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW30_07020	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW30_07030	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW30_07035	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW30_07040	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW30_07045	COG0107	imidazoleglycerol-phosphate synthase activity
EXW30_07055	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW30_07060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW30_07075	COG1183	phosphatidylcholine synthase activity
EXW30_07080	COG1368	sulfuric ester hydrolase activity
EXW30_07090	COG0019	diaminopimelate decarboxylase activity
EXW30_07105	COG2046	Belongs to the sulfate adenylyltransferase family
EXW30_07110	COG0529	Catalyzes the synthesis of activated sulfate
EXW30_07115	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW30_07135	COG1648	precorrin-2 dehydrogenase activity
EXW30_07140	COG0733	neurotransmitter:sodium symporter activity
EXW30_07160	COG1757	Na H antiporter
EXW30_07175	COG4758	membrane
EXW30_07180	COG4585	Histidine kinase
EXW30_07185	COG2197	response regulator
EXW30_07195	COG1114	Component of the transport system for branched-chain amino acids
EXW30_07205	COG2226	methyltransferase
EXW30_07245	COG0730	response to heat
EXW30_07250	COG0306	phosphate transporter
EXW30_07255	COG1392	Phosphate transport regulator
EXW30_07260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW30_07275	COG3852	Histidine kinase
EXW30_07280	COG1801	Protein of unknown function DUF72
EXW30_07290	COG0582	viral genome integration into host DNA
EXW30_07295	COG5002	protein histidine kinase activity
EXW30_07310	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW30_07310	COG0392	lysyltransferase activity
EXW30_07325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW30_07330	COG1686	Belongs to the peptidase S11 family
EXW30_07335	COG2715	membrane protein required for spore maturation
EXW30_07340	COG0700	Nucleoside recognition
EXW30_07345	COG1187	pseudouridine synthase activity
EXW30_07355	COG1333	cytochrome c biogenesis protein
EXW30_07360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW30_07365	COG0745	RESPONSE REGULATOR receiver
EXW30_07370	COG5002	protein histidine kinase activity
EXW30_07375	COG2096	Adenosyltransferase
EXW30_07380	COG4942	peptidase
EXW30_07390	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW30_07395	COG1141	Ferredoxin
EXW30_07405	COG4955	Helix-turn-helix domain
EXW30_07410	COG0514	ATP-dependent DNA helicase (RecQ)
EXW30_07415	COG1266	CAAX protease self-immunity
EXW30_07425	COG1408	metallophosphoesterase
EXW30_07440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW30_07455	COG0492	ferredoxin-NADP+ reductase activity
EXW30_07460	COG0252	asparaginase activity
EXW30_07470	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW30_07480	COG1304	FMN binding
EXW30_07510	COG1160	GTP binding
EXW30_07515	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW30_07535	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW30_07550	COG0142	geranyltranstransferase activity
EXW30_07555	COG2226	methyltransferase
EXW30_07560	COG0142	geranyltranstransferase activity
EXW30_07575	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW30_07585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW30_07590	COG0457	Tetratricopeptide repeat
EXW30_07595	COG5582	Belongs to the UPF0302 family
EXW30_07610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW30_07615	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW30_07615	COG2010	Cytochrome c
EXW30_07620	COG4347	Protein of unknown function (DUF1405)
EXW30_07635	COG2738	Putative neutral zinc metallopeptidase
EXW30_07645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW30_07655	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW30_07660	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW30_07665	COG1803	Methylglyoxal synthase
EXW30_07670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW30_07675	COG0438	transferase activity, transferring glycosyl groups
EXW30_07680	COG0617	tRNA 3'-terminal CCA addition
EXW30_07690	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW30_07695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW30_07705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW30_07705	COG1199	ATP-dependent helicase activity
EXW30_07725	COG3935	DnaD domain protein
EXW30_07730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW30_07740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW30_07740	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW30_07745	COG3331	DNA recombination
EXW30_07780	COG4474	Belongs to the UPF0398 family
EXW30_07785	COG3599	regulation of cell shape
EXW30_07795	COG0116	Belongs to the methyltransferase superfamily
EXW30_07805	COG1199	ATP-dependent helicase activity
EXW30_07810	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW30_07820	COG0024	Methionine aminopeptidase
EXW30_07830	COG2233	PERMEase
EXW30_07835	COG2311	Membrane
EXW30_07840	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW30_07850	COG0456	acetyltransferase
EXW30_07860	COG2897	thiosulfate sulfurtransferase activity
EXW30_07900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW30_07940	COG0328	RNA-DNA hybrid ribonuclease activity
EXW30_07995	COG3403	YqcI/YcgG family
EXW30_08000	COG1280	lysine exporter protein (LysE YggA)
EXW30_08015	COG3162	membrane
EXW30_08020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW30_08025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW30_08035	COG0475	glutathione-regulated potassium exporter activity
EXW30_08040	COG0789	Transcriptional regulator
EXW30_08040	COG4978	Transcriptional regulator
EXW30_08050	COG2323	membrane
EXW30_08055	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW30_08075	COG1609	Transcriptional regulator
EXW30_08085	COG1175	transmembrane transport
EXW30_08090	COG0395	ABC-type sugar transport system, permease component
EXW30_08095	COG5578	integral membrane protein
EXW30_08105	COG1486	melibiose metabolic process
EXW30_08120	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EXW30_08125	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW30_08130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW30_08170	COG1923	regulation of RNA biosynthetic process
EXW30_08180	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW30_08185	COG1360	Flagellar Motor Protein
EXW30_08190	COG2201	protein-glutamate methylesterase activity
EXW30_08195	COG2198	Histidine kinase
EXW30_08195	COG0643	Histidine kinase
EXW30_08200	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW30_08200	COG1776	CheC inhibitor of MCP methylation
EXW30_08215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW30_08235	COG1256	bacterial-type flagellum assembly
EXW30_08240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW30_08260	COG1815	bacterial-type flagellum-dependent cell motility
EXW30_08265	COG1558	bacterial-type flagellum-dependent cell motility
EXW30_08275	COG1766	The M ring may be actively involved in energy transduction
EXW30_08280	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW30_08290	COG1157	protein secretion by the type III secretion system
EXW30_08310	COG1749	Flagellar hook protein flgE
EXW30_08325	COG0784	Response regulator, receiver
EXW30_08325	COG0835	chemotaxis
EXW30_08335	COG0861	Integral membrane protein TerC family
EXW30_08345	COG3383	formate dehydrogenase (NAD+) activity
EXW30_08350	COG2427	Protein of unknown function (DUF1641)
EXW30_08355	COG5609	conserved protein (DUF2294)
EXW30_08360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW30_08370	COG2116	formate transmembrane transporter activity
EXW30_08375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW30_08380	COG0303	'Molybdopterin
EXW30_08385	COG0314	molybdopterin synthase activity
EXW30_08400	COG0489	protein tyrosine kinase activity
EXW30_08405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW30_08410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW30_08415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW30_08420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW30_08425	COG0741	lytic transglycosylase activity
EXW30_08435	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW30_08440	COG1776	CheC inhibitor of MCP methylation
EXW30_08440	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW30_08450	COG1338	Plays a role in the flagellum-specific transport system
EXW30_08455	COG1987	bacterial-type flagellum assembly
EXW30_08465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW30_08470	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW30_08475	COG1419	protein localization to endoplasmic reticulum
EXW30_08480	COG4786	Flagellar basal body rod
EXW30_08515	COG0412	Dienelactone hydrolase
EXW30_08520	COG2329	Antibiotic biosynthesis monooxygenase
EXW30_08535	COG3764	Sortase (surface protein transpeptidase)
EXW30_08540	COG3764	Sortase (surface protein transpeptidase)
EXW30_08565	COG0583	DNA-binding transcription factor activity
EXW30_08570	COG3842	ATPase activity
EXW30_08575	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW30_08610	COG0406	alpha-ribazole phosphatase activity
EXW30_08630	COG1846	Transcriptional regulator
EXW30_08640	COG0367	asparagine synthase
EXW30_08670	COG1757	Na H antiporter
EXW30_08680	COG0277	FAD linked oxidase domain protein
EXW30_08695	COG0534	Mate efflux family protein
EXW30_08700	COG3340	Belongs to the peptidase S51 family
EXW30_08720	COG0785	Cytochrome C biogenesis protein
EXW30_08740	COG3048	D-serine ammonia-lyase activity
EXW30_08745	COG2733	membrane
EXW30_08790	COG1131	(ABC) transporter
EXW30_08810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW30_08815	COG0528	UMP kinase activity
EXW30_08825	COG1027	Aspartate ammonia-lyase
EXW30_08830	COG0281	malic enzyme
EXW30_08835	COG4191	Histidine kinase
EXW30_08840	COG0784	Response regulator, receiver
EXW30_08845	COG1846	Transcriptional regulator
EXW30_08855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW30_08870	COG2502	aspartate--ammonia ligase
EXW30_08875	COG3620	sequence-specific DNA binding
EXW30_08920	COG1695	Transcriptional regulator
EXW30_08935	COG0477	Major facilitator Superfamily
EXW30_08955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW30_08960	COG4166	transmembrane transport
EXW30_08965	COG2223	nitrite transmembrane transporter activity
EXW30_08970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW30_08985	COG2244	polysaccharide biosynthetic process
EXW30_08990	COG0733	neurotransmitter:sodium symporter activity
EXW30_09000	COG5566	PFAM Mor transcription activator
EXW30_09005	COG2323	membrane
EXW30_09020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW30_09035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW30_09060	COG2814	Major facilitator Superfamily
EXW30_09065	COG3384	dioxygenase
EXW30_09100	COG4166	transmembrane transport
EXW30_09130	COG0737	Belongs to the 5'-nucleotidase family
EXW30_09140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW30_09150	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW30_09155	COG1054	Belongs to the UPF0176 family
EXW30_09165	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW30_09170	COG0531	amino acid
EXW30_09190	COG1280	lysine exporter protein (LysE YggA)
EXW30_09205	COG2390	Transcriptional regulator
EXW30_09210	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW30_09215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW30_09220	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW30_09235	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW30_09255	COG2267	carboxylic ester hydrolase activity
EXW30_09260	COG0583	DNA-binding transcription factor activity
EXW30_09275	COG0006	proline dipeptidase activity
EXW30_09285	COG2132	Multicopper oxidase
EXW30_09300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW30_09310	COG0583	DNA-binding transcription factor activity
EXW30_09330	COG1114	Component of the transport system for branched-chain amino acids
EXW30_09340	COG2372	response to copper ion
EXW30_09340	COG1276	copper resistance
EXW30_09350	COG4549	nuclear export factor GLE1
EXW30_09360	COG0697	spore germination
EXW30_09365	COG0583	DNA-binding transcription factor activity
EXW30_09370	COG1959	2 iron, 2 sulfur cluster binding
EXW30_09375	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW30_09390	COG0628	permease
EXW30_09405	COG1231	oxidoreductase activity
EXW30_09410	COG0523	cobalamin synthesis protein
EXW30_09420	COG0411	ABC transporter
EXW30_09440	COG0583	DNA-binding transcription factor activity
EXW30_09465	COG0346	lactoylglutathione lyase activity
EXW30_09475	COG1271	oxidase subunit
EXW30_09480	COG1294	oxidase, subunit
EXW30_09485	COG4988	ABC transporter
EXW30_09490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW30_09515	COG1686	Belongs to the peptidase S11 family
EXW30_09525	COG0791	NLP P60 protein
EXW30_09525	COG1388	LysM domain
EXW30_09535	COG1132	(ABC) transporter
EXW30_09540	COG0745	RESPONSE REGULATOR receiver
EXW30_09545	COG5002	protein histidine kinase activity
EXW30_09550	COG0300	oxidoreductase activity
EXW30_09555	COG4122	O-methyltransferase activity
EXW30_09585	COG0460	homoserine dehydrogenase
EXW30_09595	COG0083	homoserine kinase activity
EXW30_09610	COG1316	TRANSCRIPTIONal
EXW30_09625	COG1285	pathogenesis
EXW30_09650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW30_09660	COG1082	Xylose isomerase domain protein TIM barrel
EXW30_09670	COG2814	Major facilitator Superfamily
EXW30_09675	COG1279	arginine transmembrane transporter activity
EXW30_09680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW30_09690	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW30_09725	COG0577	efflux transmembrane transporter activity
EXW30_09730	COG2002	toxin-antitoxin pair type II binding
EXW30_09745	COG1404	Belongs to the peptidase S8 family
EXW30_09755	COG3842	ATPase activity
EXW30_09760	COG2508	Transcriptional regulator
EXW30_09770	COG1653	transport
EXW30_09775	COG1175	transmembrane transport
EXW30_09780	COG0395	ABC-type sugar transport system, permease component
EXW30_09785	COG5426	von Willebrand factor, type A
EXW30_09790	COG1940	carbohydrate kinase activity
EXW30_09795	COG2222	sugar isomerase
EXW30_09805	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW30_09810	COG3684	Belongs to the aldolase LacD family
EXW30_09815	COG0366	Alpha amylase catalytic
EXW30_09820	COG0366	Alpha amylase catalytic
EXW30_09825	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW30_09870	COG3949	Membrane
EXW30_09875	COG0783	Belongs to the Dps family
EXW30_09890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW30_09900	COG1231	oxidoreductase activity
EXW30_09905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW30_09910	COG4989	oxidoreductase activity
EXW30_09915	COG0523	cobalamin synthesis protein
EXW30_09920	COG0456	acetyltransferase
EXW30_09925	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW30_09935	COG0702	epimerase
EXW30_09945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW30_09955	COG4166	transmembrane transport
EXW30_09960	COG0346	lactoylglutathione lyase activity
EXW30_09970	COG0406	alpha-ribazole phosphatase activity
EXW30_09980	COG5337	Spore coat protein CotH
EXW30_09985	COG1051	belongs to the nudix hydrolase family
EXW30_09990	COG0586	Pfam SNARE associated Golgi protein
EXW30_09995	COG2244	polysaccharide biosynthetic process
EXW30_10005	COG0701	Predicted permease
EXW30_10010	COG3689	TIGRFAM TIGR03943 family protein
EXW30_10015	COG1607	acyl-coa hydrolase
EXW30_10025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW30_10040	COG0702	epimerase
EXW30_10045	COG2839	Protein conserved in bacteria
EXW30_10050	COG1253	flavin adenine dinucleotide binding
EXW30_10065	COG1114	Component of the transport system for branched-chain amino acids
EXW30_10070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW30_10090	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW30_10100	COG1876	peptidase activity
EXW30_10115	COG2211	Major facilitator Superfamily
EXW30_10130	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW30_10140	COG0561	phosphatase activity
EXW30_10150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW30_10170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW30_10175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW30_10200	COG0456	acetyltransferase
EXW30_10275	COG4974	Belongs to the 'phage' integrase family
EXW30_10285	COG3874	Sporulation protein YtfJ
EXW30_10310	COG2226	methyltransferase
EXW30_10330	COG0346	lactoylglutathione lyase activity
EXW30_10340	COG0604	alcohol dehydrogenase
EXW30_10345	COG1595	DNA-templated transcription, initiation
EXW30_10360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW30_10360	COG0426	domain, Protein
EXW30_10370	COG0386	Belongs to the glutathione peroxidase family
EXW30_10375	COG1305	Transglutaminase-like
EXW30_10380	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW30_10385	COG0714	Associated with various cellular activities
EXW30_10400	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW30_10405	COG1140	nitrate reductase beta subunit
EXW30_10410	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW30_10415	COG2181	nitrate reductase activity
EXW30_10420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW30_10425	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW30_10430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW30_10435	COG0303	'Molybdopterin
EXW30_10440	COG0314	molybdopterin synthase activity
EXW30_10450	COG2223	nitrite transmembrane transporter activity
EXW30_10460	COG1648	precorrin-2 dehydrogenase activity
EXW30_10470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW30_10470	COG1587	Uroporphyrinogen-III synthase
EXW30_10475	COG2146	nitrite reductase [NAD(P)H] activity
EXW30_10480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW30_10490	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW30_10515	COG2359	stage V sporulation protein S
EXW30_10525	COG2856	Zn peptidase
EXW30_10535	COG0494	nUDIX hydrolase
EXW30_10550	COG1396	sequence-specific DNA binding
EXW30_10585	COG0305	Participates in initiation and elongation during chromosome replication
EXW30_10615	COG0582	viral genome integration into host DNA
EXW30_10660	COG0740	serine-type endopeptidase activity
EXW30_10735	COG4824	toxin secretion phage lysis holin
EXW30_10740	COG1388	LysM domain
EXW30_10740	COG3409	Peptidoglycan-binding domain 1 protein
EXW30_10740	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW30_10755	COG1418	mRNA catabolic process
EXW30_10760	COG0488	(ABC) transporter
EXW30_10775	COG0629	single-stranded DNA binding
EXW30_10795	COG1413	lyase activity
EXW30_10810	COG2521	methyltransferase
EXW30_10810	COG2136	Putative SAM-dependent methyltransferase
EXW30_10815	COG0018	arginyl-trna synthetase
EXW30_10870	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW30_10880	COG0017	Asparaginyl-tRNA synthetase
EXW30_10900	COG1674	ftsk spoiiie
EXW30_10955	COG0733	neurotransmitter:sodium symporter activity
EXW30_10980	COG2610	gluconate transmembrane transporter activity
EXW30_10985	COG1454	alcohol dehydrogenase
EXW30_11000	COG0456	acetyltransferase
EXW30_11005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW30_11015	COG1131	(ABC) transporter
EXW30_11020	COG4473	ABC transporter
EXW30_11030	COG0546	phosphoglycolate phosphatase activity
EXW30_11055	COG0671	phosphoesterase, PA-phosphatase related
EXW30_11075	COG0768	penicillin binding
EXW30_11090	COG1272	protein, Hemolysin III
EXW30_11095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW30_11100	COG0805	protein transport
EXW30_11110	COG1307	EDD domain protein, DegV family
EXW30_11115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW30_11120	COG1999	signal sequence binding
EXW30_11125	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW30_11130	COG0367	asparagine synthase
EXW30_11145	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW30_11150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW30_11155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW30_11170	COG1335	isochorismatase
EXW30_11175	COG1051	belongs to the nudix hydrolase family
EXW30_11180	COG0668	transmembrane transport
EXW30_11185	COG4585	Histidine kinase
EXW30_11185	COG2203	Gaf domain
EXW30_11190	COG2197	response regulator
EXW30_11195	COG1737	Transcriptional regulator
EXW30_11200	COG1064	alcohol dehydrogenase
EXW30_11215	COG1070	Carbohydrate kinase
EXW30_11225	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW30_11245	COG1125	glycine betaine transport
EXW30_11245	COG0517	IMP dehydrogenase activity
EXW30_11250	COG1174	glycine betaine transport
EXW30_11285	COG1253	flavin adenine dinucleotide binding
EXW30_11290	COG1012	belongs to the aldehyde dehydrogenase family
EXW30_11295	COG5506	Protein of unknown function (DUF1694)
EXW30_11310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW30_11315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW30_11320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW30_11325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW30_11330	COG0456	acetyltransferase
EXW30_11335	COG3829	transcription factor binding
EXW30_11340	COG1509	lysine 2,3-aminomutase activity
EXW30_11350	COG4479	Belongs to the UPF0346 family
EXW30_11375	COG3064	Membrane
EXW30_11375	COG4991	sh3 domain protein
EXW30_11375	COG0515	serine threonine protein kinase
EXW30_11385	COG0671	phosphoesterase, PA-phosphatase related
EXW30_11390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW30_11395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW30_11400	COG0582	viral genome integration into host DNA
EXW30_11460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW30_11485	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_11515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW30_11515	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW30_11525	COG2814	Major facilitator Superfamily
EXW30_11530	COG0372	Belongs to the citrate synthase family
EXW30_11535	COG2079	MmgE PrpD family protein
EXW30_11540	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW30_11545	COG1960	acyl-CoA dehydrogenase activity
EXW30_11550	COG2084	Dehydrogenase
EXW30_11555	COG1012	belongs to the aldehyde dehydrogenase family
EXW30_11560	COG1280	lysine exporter protein (LysE YggA)
EXW30_11565	COG1024	Enoyl-CoA hydratase
EXW30_11580	COG0420	3'-5' exonuclease activity
EXW30_11585	COG0419	ATPase involved in DNA repair
EXW30_11600	COG2223	nitrite transmembrane transporter activity
EXW30_11605	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_11610	COG1169	isochorismate synthase
EXW30_11615	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW30_11620	COG3433	isochorismatase activity
EXW30_11620	COG1535	isochorismatase
EXW30_11625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW30_11630	COG3251	PFAM MbtH domain protein
EXW30_11635	COG2814	Major facilitator Superfamily
EXW30_11650	COG0776	regulation of translation
EXW30_11660	COG1115	amino acid carrier protein
EXW30_11675	COG2329	Antibiotic biosynthesis monooxygenase
EXW30_11690	COG1187	pseudouridine synthase activity
EXW30_11695	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW30_11720	COG1136	(ABC) transporter
EXW30_11745	COG0028	Belongs to the TPP enzyme family
EXW30_11755	COG4974	Belongs to the 'phage' integrase family
EXW30_11775	COG1253	flavin adenine dinucleotide binding
EXW30_11830	COG1846	Transcriptional regulator
EXW30_11845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW30_11850	COG1309	transcriptional regulator
EXW30_11860	COG0697	spore germination
EXW30_11865	COG0531	amino acid
EXW30_11880	COG1247	-acetyltransferase
EXW30_11910	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW30_11920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW30_11945	COG0561	phosphatase activity
EXW30_11955	COG0583	DNA-binding transcription factor activity
EXW30_11960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW30_12005	COG0583	DNA-binding transcription factor activity
EXW30_12010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW30_12015	COG2258	MOSC domain
EXW30_12030	COG1132	(ABC) transporter
EXW30_12035	COG1132	(ABC) transporter
EXW30_12050	COG0189	ligase activity
EXW30_12070	COG1396	sequence-specific DNA binding
EXW30_12155	COG1309	transcriptional regulator
EXW30_12170	COG0577	efflux transmembrane transporter activity
EXW30_12170	COG1136	(ABC) transporter
EXW30_12175	COG3615	Tellurite resistance protein tehB
EXW30_12175	COG0500	methyltransferase
EXW30_12185	COG0693	protein deglycase activity
EXW30_12240	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW30_12245	COG0110	maltose O-acetyltransferase activity
EXW30_12255	COG1686	Belongs to the peptidase S11 family
EXW30_12300	COG0768	penicillin binding
EXW30_12305	COG1595	DNA-templated transcription, initiation
EXW30_12315	COG0768	penicillin binding
EXW30_12320	COG0768	penicillin binding
EXW30_12340	COG0697	spore germination
EXW30_12365	COG3397	chitin binding
EXW30_12370	COG0823	Involved in the tonB-independent uptake of proteins
EXW30_12380	COG1408	metallophosphoesterase
EXW30_12390	COG1131	(ABC) transporter
EXW30_12400	COG1309	transcriptional regulator
EXW30_12410	COG1960	acyl-CoA dehydrogenase activity
EXW30_12415	COG0439	Biotin carboxylase
EXW30_12420	COG0511	ligase activity, forming carbon-carbon bonds
EXW30_12425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW30_12430	COG1024	Enoyl-CoA hydratase
EXW30_12435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW30_12440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW30_12475	COG0572	uridine kinase
EXW30_12480	COG2318	DinB family
EXW30_12485	COG1686	Belongs to the peptidase S11 family
EXW30_12510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW30_12530	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW30_12535	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_12540	COG1733	regulation of RNA biosynthetic process
EXW30_12580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW30_12595	COG0697	spore germination
EXW30_12600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW30_12635	COG2323	membrane
EXW30_12640	COG2132	Multicopper oxidase
EXW30_12655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW30_12660	COG0697	spore germination
EXW30_12665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW30_12670	COG0201	protein transport
EXW30_12680	COG0737	Belongs to the 5'-nucleotidase family
EXW30_12685	COG3227	Zinc metalloprotease (Elastase)
EXW30_12690	COG1523	belongs to the glycosyl hydrolase 13 family
EXW30_12695	COG1073	alpha beta
EXW30_12705	COG0577	efflux transmembrane transporter activity
EXW30_12710	COG1136	(ABC) transporter
EXW30_12740	COG5002	protein histidine kinase activity
EXW30_12745	COG0745	RESPONSE REGULATOR receiver
EXW30_12750	COG1011	Hydrolase
EXW30_12775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW30_12780	COG1183	phosphatidylcholine synthase activity
EXW30_12790	COG1132	(ABC) transporter
EXW30_12800	COG3961	Belongs to the TPP enzyme family
EXW30_12820	COG0322	excinuclease ABC activity
EXW30_12845	COG2318	DinB family
EXW30_12860	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW30_12880	COG3878	Protein conserved in bacteria
EXW30_12910	COG1051	belongs to the nudix hydrolase family
EXW30_12915	COG0592	DNA-directed DNA polymerase activity
EXW30_12930	COG2223	nitrite transmembrane transporter activity
EXW30_12935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW30_12945	COG0494	nUDIX hydrolase
EXW30_12965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW30_12980	COG0584	glycerophosphoryl diester phosphodiesterase
EXW30_12995	COG2814	Major facilitator Superfamily
EXW30_13035	COG0768	penicillin binding
EXW30_13040	COG0671	phosphoesterase, PA-phosphatase related
EXW30_13045	COG0604	alcohol dehydrogenase
EXW30_13050	COG5002	protein histidine kinase activity
EXW30_13055	COG0745	RESPONSE REGULATOR receiver
EXW30_13065	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW30_13075	COG2205	protein histidine kinase activity
EXW30_13090	COG1122	ATPase activity
EXW30_13095	COG4720	Psort location CytoplasmicMembrane, score
EXW30_13100	COG1794	racemase activity, acting on amino acids and derivatives
EXW30_13105	COG1819	glycosyl
EXW30_13115	COG0768	penicillin binding
EXW30_13120	COG5002	protein histidine kinase activity
EXW30_13125	COG0561	phosphatase activity
EXW30_13165	COG2124	cytochrome p450
EXW30_13210	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW30_13220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW30_13225	COG0460	homoserine dehydrogenase
EXW30_13245	COG0577	efflux transmembrane transporter activity
EXW30_13250	COG1136	(ABC) transporter
EXW30_13265	COG0488	(ABC) transporter
EXW30_13270	COG0667	Aldo Keto reductase
EXW30_13275	COG0583	DNA-binding transcription factor activity
EXW30_13280	COG2205	protein histidine kinase activity
EXW30_13285	COG0745	RESPONSE REGULATOR receiver
EXW30_13295	COG3773	Cell wall hydrolase
EXW30_13300	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW30_13340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW30_13355	COG2959	enzyme of heme biosynthesis
EXW30_13380	COG3483	tryptophan 2,3-dioxygenase activity
EXW30_13390	COG3844	kynureninase activity
EXW30_13395	COG1309	transcriptional regulator
EXW30_13425	COG1349	DNA-binding transcription factor activity
EXW30_13455	COG2223	nitrite transmembrane transporter activity
EXW30_13465	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_13470	COG0456	acetyltransferase
EXW30_13470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW30_13480	COG2816	NAD+ diphosphatase activity
EXW30_13515	COG4176	ABC-type proline glycine betaine transport system permease component
EXW30_13520	COG0517	IMP dehydrogenase activity
EXW30_13520	COG4175	Glycine betaine
EXW30_13545	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW30_13550	COG2153	protein acetylation
EXW30_13555	COG1132	(ABC) transporter
EXW30_13560	COG1819	glycosyl
EXW30_13580	COG2205	protein histidine kinase activity
EXW30_13585	COG2315	Protein conserved in bacteria
EXW30_13630	COG3973	AAA domain
EXW30_13635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW30_13655	COG0514	ATP-dependent DNA helicase (RecQ)
EXW30_13685	COG4637	Psort location Cytoplasmic, score
EXW30_13705	COG1227	inorganic diphosphatase activity
EXW30_13710	COG2318	DinB family
EXW30_13725	COG1162	GTPase activity
EXW30_13730	COG1115	amino acid carrier protein
EXW30_13735	COG1012	belongs to the aldehyde dehydrogenase family
EXW30_13740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW30_13750	COG3938	Belongs to the proline racemase family
EXW30_13755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW30_13800	COG1078	dGTPase activity
EXW30_13805	COG0586	Pfam SNARE associated Golgi protein
EXW30_13820	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW30_13825	COG4166	transmembrane transport
EXW30_13835	COG4948	Mandelate Racemase Muconate Lactonizing
EXW30_13855	COG0667	Aldo Keto reductase
EXW30_13900	COG2936	dipeptidyl-peptidase activity
EXW30_13910	COG0745	RESPONSE REGULATOR receiver
EXW30_13940	COG1164	Oligoendopeptidase f
EXW30_13965	COG1307	EDD domain protein, DegV family
EXW30_14005	COG2814	Major facilitator Superfamily
EXW30_14015	COG1664	Polymer-forming cytoskeletal
EXW30_14020	COG0789	Transcriptional regulator
EXW30_14025	COG4533	DNA binding
EXW30_14030	COG2814	Major facilitator Superfamily
EXW30_14030	COG0477	Major facilitator Superfamily
EXW30_14045	COG2261	transglycosylase associated protein
EXW30_14060	COG2226	methyltransferase
EXW30_14095	COG0436	Aminotransferase
EXW30_14100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW30_14110	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW30_14125	COG1131	(ABC) transporter
EXW30_14175	COG0628	permease
EXW30_14200	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW30_14205	COG2720	vancomycin resistance protein
EXW30_14225	COG0697	spore germination
EXW30_14245	COG4912	Dna alkylation repair
EXW30_14280	COG2814	Major facilitator Superfamily
EXW30_14285	COG1368	sulfuric ester hydrolase activity
EXW30_14295	COG0488	(ABC) transporter
EXW30_14305	COG2409	Drug exporters of the RND superfamily
EXW30_14305	COG1033	growth of symbiont in host cell
EXW30_14310	COG1309	transcriptional regulator
EXW30_14325	COG0287	Prephenate dehydrogenase
EXW30_14340	COG1605	Chorismate mutase
EXW30_14340	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW30_14375	COG3584	3D domain protein
EXW30_14375	COG1388	LysM domain
EXW30_14385	COG0346	lactoylglutathione lyase activity
EXW30_14395	COG0431	NADPH-dependent FMN reductase
EXW30_14405	COG1595	DNA-templated transcription, initiation
EXW30_14425	COG0579	oxidoreductase
EXW30_14430	COG1879	ABC-type sugar transport system periplasmic component
EXW30_14435	COG2390	Transcriptional regulator
EXW30_14440	COG1070	Carbohydrate kinase
EXW30_14455	COG2226	methyltransferase
EXW30_14490	COG0346	lactoylglutathione lyase activity
EXW30_14495	COG2329	Antibiotic biosynthesis monooxygenase
EXW30_14515	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW30_14520	COG2207	Transcriptional regulator
EXW30_14525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW30_14530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW30_14535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW30_14540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW30_14545	COG3239	Fatty acid desaturase
EXW30_14565	COG3842	ATPase activity
EXW30_14590	COG1175	transmembrane transport
EXW30_14595	COG1349	DNA-binding transcription factor activity
EXW30_14605	COG3655	Transcriptional regulator
EXW30_14625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW30_14630	COG0346	lactoylglutathione lyase activity
EXW30_14655	COG0714	Associated with various cellular activities
EXW30_14680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW30_14685	COG0753	catalase activity
EXW30_14725	COG0714	Associated with various cellular activities
EXW30_14735	COG0778	Nitroreductase
EXW30_14740	COG1846	Transcriptional regulator
EXW30_14770	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW30_14785	COG0824	Thioesterase
EXW30_14790	COG0318	PFAM AMP-dependent synthetase and ligase
EXW30_14795	COG0183	Belongs to the thiolase family
EXW30_14800	COG1024	Enoyl-CoA hydratase
EXW30_14805	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW30_14810	COG2723	6-phospho-beta-galactosidase activity
EXW30_14815	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW30_14820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW30_14835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW30_14845	COG2508	Transcriptional regulator
EXW30_14850	COG2814	Major facilitator Superfamily
EXW30_14895	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_14900	COG1309	transcriptional regulator
EXW30_14920	COG0456	acetyltransferase
EXW30_14935	COG0697	spore germination
EXW30_14940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW30_14945	COG1671	Belongs to the UPF0178 family
EXW30_14960	COG0642	Histidine kinase
EXW30_14965	COG0745	RESPONSE REGULATOR receiver
EXW30_14970	COG0596	Alpha beta hydrolase
EXW30_14980	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW30_14980	COG0456	acetyltransferase
EXW30_15005	COG0730	response to heat
EXW30_15015	COG0833	amino acid
EXW30_15025	COG4335	DNA alkylation repair
EXW30_15065	COG0768	penicillin binding
EXW30_15080	COG3104	oligopeptide transport
EXW30_15085	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW30_15100	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW30_15105	COG1984	allophanate hydrolase subunit 2
EXW30_15110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW30_15115	COG1414	Transcriptional regulator
EXW30_15135	COG1960	acyl-CoA dehydrogenase activity
EXW30_15170	COG0640	Transcriptional regulator
EXW30_15195	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW30_15215	COG3848	Pyruvate phosphate dikinase
EXW30_15215	COG0574	Belongs to the PEP-utilizing enzyme family
EXW30_15270	COG0798	PFAM Bile acid sodium symporter
EXW30_15275	COG0346	lactoylglutathione lyase activity
EXW30_15280	COG0640	Transcriptional regulator
EXW30_15295	COG1309	transcriptional regulator
EXW30_15300	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_15305	COG1522	sequence-specific DNA binding
EXW30_15320	COG0346	lactoylglutathione lyase activity
EXW30_15335	COG0457	Tetratricopeptide repeat
EXW30_15350	COG0745	RESPONSE REGULATOR receiver
EXW30_15355	COG3850	Histidine kinase
EXW30_15355	COG5002	protein histidine kinase activity
EXW30_15400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW30_15405	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW30_15435	COG2226	methyltransferase
EXW30_15445	COG5658	integral membrane protein
EXW30_15455	COG1690	Belongs to the RtcB family
EXW30_15465	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW30_15470	COG3344	reverse transcriptase
EXW30_15490	COG1136	(ABC) transporter
EXW30_15495	COG0577	efflux transmembrane transporter activity
EXW30_15515	COG3344	reverse transcriptase
EXW30_15520	COG3850	Histidine kinase
EXW30_15520	COG5002	protein histidine kinase activity
EXW30_15530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW30_15560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW30_15590	COG5444	nuclease activity
EXW30_15615	COG2814	Major facilitator Superfamily
EXW30_15650	COG1876	peptidase activity
EXW30_15655	COG2843	Capsule synthesis protein
EXW30_15670	COG0477	Major facilitator Superfamily
EXW30_15685	COG1846	Transcriptional regulator
EXW30_15690	COG2814	Major facilitator Superfamily
EXW30_15740	COG3344	reverse transcriptase
EXW30_15800	COG0384	phenazine biosynthesis protein PhzF
EXW30_15825	COG4187	Peptidase family M20/M25/M40
EXW30_15830	COG1414	Transcriptional regulator
EXW30_15840	COG0833	amino acid
EXW30_15855	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW30_15870	COG2031	fatty acid transporter
EXW30_15880	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW30_15930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW30_15940	COG3344	reverse transcriptase
EXW30_15945	COG2356	endonuclease I
EXW30_15950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW30_15955	COG0412	Dienelactone hydrolase
EXW30_15975	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW30_16005	COG1785	Belongs to the alkaline phosphatase family
EXW30_16020	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_16030	COG1131	(ABC) transporter
EXW30_16055	COG1011	Hydrolase
EXW30_16065	COG2365	Tyrosine phosphatase family
EXW30_16090	COG0346	lactoylglutathione lyase activity
EXW30_16095	COG1940	carbohydrate kinase activity
EXW30_16100	COG0738	Major facilitator superfamily
EXW30_16105	COG0110	maltose O-acetyltransferase activity
EXW30_16120	COG0628	permease
EXW30_16140	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW30_16150	COG1253	flavin adenine dinucleotide binding
EXW30_16155	COG0789	Transcriptional regulator
EXW30_16160	COG0697	spore germination
EXW30_16165	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW30_16170	COG3813	Protein conserved in bacteria
EXW30_16175	COG4702	Belongs to the UPF0303 family
EXW30_16185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW30_16195	COG0494	nUDIX hydrolase
EXW30_16210	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_16220	COG0318	PFAM AMP-dependent synthetase and ligase
EXW30_16225	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW30_16230	COG1733	regulation of RNA biosynthetic process
EXW30_16235	COG0640	Transcriptional regulator
EXW30_16255	COG1191	sigma factor activity
EXW30_16305	COG0500	methyltransferase
EXW30_16305	COG3615	Tellurite resistance protein tehB
EXW30_16315	COG0657	acetylesterase activity
EXW30_16325	COG2814	Major facilitator Superfamily
EXW30_16330	COG1309	transcriptional regulator
EXW30_16345	COG2224	Isocitrate lyase
EXW30_16405	COG0814	amino acid
EXW30_16435	COG1151	hydroxylamine reductase activity
EXW30_16440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW30_16465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW30_16475	COG2072	flavoprotein involved in K transport
EXW30_16520	COG0714	Associated with various cellular activities
EXW30_16570	COG1695	Transcriptional regulator
EXW30_16575	COG0604	alcohol dehydrogenase
EXW30_16580	COG1113	amino acid transport
EXW30_16585	COG0456	acetyltransferase
EXW30_16600	COG5002	protein histidine kinase activity
EXW30_16605	COG0745	RESPONSE REGULATOR receiver
EXW30_16610	COG5002	protein histidine kinase activity
EXW30_16620	COG2814	Major facilitator Superfamily
EXW30_16630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW30_16635	COG1012	belongs to the aldehyde dehydrogenase family
EXW30_16645	COG0534	Mate efflux family protein
EXW30_16650	COG1012	belongs to the aldehyde dehydrogenase family
EXW30_16655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW30_16670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW30_16675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW30_16695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW30_16700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW30_16705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW30_16710	COG3739	integral membrane protein
EXW30_16725	COG0583	DNA-binding transcription factor activity
EXW30_16745	COG1193	negative regulation of DNA recombination
EXW30_16755	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW30_16760	COG1164	Oligoendopeptidase f
EXW30_16785	COG3781	membrane
EXW30_16795	COG2957	Belongs to the agmatine deiminase family
EXW30_16800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW30_16870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW30_16875	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW30_16880	COG0457	Tetratricopeptide repeat
EXW30_16895	COG2808	Putative FMN-binding domain
EXW30_16900	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW30_16910	COG0277	FAD linked oxidase domain protein
EXW30_16930	COG2514	catechol 2,3-dioxygenase activity
EXW30_16935	COG2720	vancomycin resistance protein
EXW30_16950	COG0110	maltose O-acetyltransferase activity
EXW30_16960	COG1278	Cold shock
EXW30_16970	COG0716	FMN binding
EXW30_17005	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_17015	COG0165	Argininosuccinate lyase
EXW30_17030	COG4145	pantothenate transmembrane transporter activity
EXW30_17040	COG1012	belongs to the aldehyde dehydrogenase family
EXW30_17045	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_17055	COG1657	PFAM Prenyltransferase squalene oxidase
EXW30_17060	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW30_17065	COG2962	Rard protein
EXW30_17075	COG0531	amino acid
EXW30_17100	COG1737	Transcriptional regulator
EXW30_17105	COG2971	BadF BadG BcrA BcrD
EXW30_17115	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW30_17120	COG1486	melibiose metabolic process
EXW30_17130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW30_17155	COG2226	methyltransferase
EXW30_17160	COG4166	transmembrane transport
EXW30_17165	COG4166	transmembrane transport
EXW30_17170	COG4166	transmembrane transport
EXW30_17175	COG1316	TRANSCRIPTIONal
EXW30_17195	COG1131	(ABC) transporter
EXW30_17205	COG0673	inositol 2-dehydrogenase activity
EXW30_17210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW30_17215	COG0187	DNA topoisomerase II activity
EXW30_17220	COG1832	CoA-binding protein
EXW30_17225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW30_17230	COG0745	RESPONSE REGULATOR receiver
EXW30_17240	COG1328	CTP reductase activity
EXW30_17250	COG4841	protein insertion into membrane
EXW30_17255	COG0824	Thioesterase
EXW30_17280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW30_17305	COG1132	(ABC) transporter
EXW30_17310	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW30_17340	COG2211	Major facilitator Superfamily
EXW30_17350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW30_17365	COG0183	Belongs to the thiolase family
EXW30_17370	COG0318	PFAM AMP-dependent synthetase and ligase
EXW30_17375	COG1268	BioY protein
EXW30_17380	COG0318	PFAM AMP-dependent synthetase and ligase
EXW30_17385	COG1396	sequence-specific DNA binding
EXW30_17405	COG3344	reverse transcriptase
EXW30_17425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW30_17440	COG5002	protein histidine kinase activity
EXW30_17450	COG0400	carboxylic ester hydrolase activity
EXW30_17460	COG0069	glutamate synthase activity
EXW30_17465	COG1902	pentaerythritol trinitrate reductase activity
EXW30_17470	COG1329	Transcriptional regulator
EXW30_17475	COG0010	Belongs to the arginase family
EXW30_17485	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW30_17490	COG2986	histidine ammonia-lyase
EXW30_17500	COG2226	methyltransferase
EXW30_17530	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW30_17535	COG0785	Cytochrome C biogenesis protein
EXW30_17550	COG1473	amidohydrolase
EXW30_17560	COG3344	reverse transcriptase
EXW30_17565	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW30_17570	COG1131	(ABC) transporter
EXW30_17585	COG0583	DNA-binding transcription factor activity
EXW30_17595	COG1346	cytolysis
EXW30_17610	COG0730	response to heat
EXW30_17635	COG1132	(ABC) transporter
EXW30_17640	COG1132	(ABC) transporter
EXW30_17645	COG3763	UPF0154 protein
EXW30_17660	COG3639	organic phosphonate transmembrane transporter activity
EXW30_17665	COG3639	organic phosphonate transmembrane transporter activity
EXW30_17675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW30_17680	COG0737	Belongs to the 5'-nucleotidase family
EXW30_17690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW30_17695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW30_17710	COG1695	Transcriptional regulator
EXW30_17715	COG1132	(ABC) transporter
EXW30_17750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW30_17760	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW30_17765	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW30_17770	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW30_17805	COG1216	Glycosyl transferase, family 2
EXW30_17830	COG1215	transferase activity, transferring glycosyl groups
EXW30_17835	COG0438	transferase activity, transferring glycosyl groups
EXW30_17840	COG0438	transferase activity, transferring glycosyl groups
EXW30_17845	COG1086	Polysaccharide biosynthesis protein
EXW30_17850	COG0489	protein tyrosine kinase activity
EXW30_17855	COG3944	biosynthesis protein
EXW30_17860	COG0174	glutamine synthetase
EXW30_17865	COG0789	Transcriptional regulator
EXW30_17870	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW30_17875	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW30_17880	COG2860	membrane
EXW30_17885	COG0464	growth
EXW30_17905	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW30_17915	COG3584	3D domain protein
EXW30_17915	COG1388	LysM domain
EXW30_17920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW30_17920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW30_17920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW30_17925	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW30_17930	COG1349	DNA-binding transcription factor activity
EXW30_17935	COG1979	alcohol dehydrogenase
EXW30_17940	COG2322	membrane
EXW30_17950	COG1473	amidohydrolase
EXW30_17955	COG1408	metallophosphoesterase
EXW30_17970	COG2217	Heavy metal translocating P-type atpase
EXW30_17975	COG2608	mercury ion transmembrane transporter activity
EXW30_17980	COG1937	Protein conserved in bacteria
EXW30_18010	COG2819	hydrolase of the alpha beta superfamily
EXW30_18015	COG1120	ATPase activity
EXW30_18020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW30_18025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW30_18030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW30_18035	COG0708	Exodeoxyribonuclease III
EXW30_18040	COG2169	Transcriptional regulator
EXW30_18045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW30_18050	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW30_18055	COG2706	6-phosphogluconolactonase activity
EXW30_18060	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW30_18065	COG2364	Membrane
EXW30_18080	COG0346	lactoylglutathione lyase activity
EXW30_18085	COG3300	MHYT domain
EXW30_18085	COG5001	Diguanylate cyclase
EXW30_18125	COG1346	cytolysis
EXW30_18135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW30_18140	COG0596	Alpha beta hydrolase
EXW30_18140	COG2945	thiolester hydrolase activity
EXW30_18145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW30_18155	COG2188	Transcriptional regulator
EXW30_18160	COG2723	6-phospho-beta-galactosidase activity
EXW30_18170	COG3773	Cell wall hydrolase
EXW30_18180	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW30_18195	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW30_18205	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW30_18210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW30_18215	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW30_18220	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW30_18220	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW30_18230	COG2359	stage V sporulation protein S
EXW30_18235	COG1692	metallophosphoesterase
EXW30_18240	COG1418	mRNA catabolic process
EXW30_18245	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW30_18250	COG1058	Belongs to the CinA family
EXW30_18250	COG1546	Belongs to the CinA family
EXW30_18255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW30_18260	COG1426	Protein conserved in bacteria
EXW30_18275	COG0300	oxidoreductase activity
EXW30_18280	COG0612	Peptidase, M16
EXW30_18285	COG0612	Peptidase, M16
EXW30_18290	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW30_18295	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW30_18300	COG3845	ABC transporter
EXW30_18305	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW30_18310	COG2188	Transcriptional regulator
EXW30_18320	COG1674	ftsk spoiiie
EXW30_18330	COG0740	serine-type endopeptidase activity
EXW30_18335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW30_18345	COG0527	aspartate kinase activity
EXW30_18350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW30_18355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW30_18360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW30_18365	COG1873	PFAM PRC-barrel domain
EXW30_18370	COG0612	Peptidase, M16
EXW30_18375	COG0726	polysaccharide deacetylase
EXW30_18380	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW30_18390	COG0196	riboflavin kinase activity
EXW30_18400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW30_18405	COG1550	Protein conserved in bacteria
EXW30_18410	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW30_18415	COG1358	cellular component organization or biogenesis
EXW30_18420	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW30_18425	COG0195	Participates in both transcription termination and antitermination
EXW30_18440	COG0442	prolyl-tRNA aminoacylation
EXW30_18445	COG0750	zinc metalloprotease
EXW30_18455	COG4589	Belongs to the CDS family
EXW30_18465	COG0233	cytoplasmic translational termination
EXW30_18470	COG0528	UMP kinase activity
EXW30_18475	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW30_18480	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW30_18485	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW30_18490	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW30_18495	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW30_18500	COG4974	Belongs to the 'phage' integrase family
EXW30_18505	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW30_18510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW30_18515	COG0758	DNA mediated transformation
EXW30_18520	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW30_18525	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW30_18530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW30_18545	COG0335	large ribosomal subunit rRNA binding
EXW30_18550	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW30_18555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW30_18560	COG1837	Belongs to the UPF0109 family
EXW30_18570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW30_18580	COG0552	protein localization to endoplasmic reticulum
EXW30_18585	COG1196	nuclear chromosome segregation
EXW30_18590	COG0571	ribonuclease III activity
EXW30_18595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW30_18600	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_18605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW30_18610	COG0416	fatty acid biosynthetic process
EXW30_18620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW30_18625	COG1461	Dihydroxyacetone kinase
EXW30_18630	COG1302	Protein conserved in bacteria
EXW30_18645	COG1564	THIamine pyrophosphokinase
EXW30_18650	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW30_18660	COG0515	serine threonine protein kinase
EXW30_18660	COG2815	serine threonine protein kinase
EXW30_18665	COG0631	protein serine/threonine phosphatase activity
EXW30_18670	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW30_18675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW30_18675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW30_18680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW30_18685	COG0242	peptide deformylase activity
EXW30_18690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW30_18695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW30_18700	COG1758	RNA polymerase activity
EXW30_18715	COG1561	YicC-like family, N-terminal region
EXW30_18720	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW30_18735	COG0006	proline dipeptidase activity
EXW30_18750	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW30_18770	COG0167	dihydroorotate dehydrogenase activity
EXW30_18775	COG0543	2 iron, 2 sulfur cluster binding
EXW30_18780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW30_18790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW30_18795	COG0540	Belongs to the ATCase OTCase family
EXW30_18805	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW30_18810	COG0564	pseudouridine synthase activity
EXW30_18830	COG3599	regulation of cell shape
EXW30_18835	COG2302	S4 RNA-binding domain
EXW30_18840	COG0762	integral membrane protein
EXW30_18845	COG1799	cell septum assembly
EXW30_18850	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW30_18860	COG1873	PFAM PRC-barrel domain
EXW30_18865	COG1191	sigma factor activity
EXW30_18870	COG1191	sigma factor activity
EXW30_18880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW30_18885	COG0849	cell division
EXW30_18890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW30_18905	COG0772	Belongs to the SEDS family
EXW30_18910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW30_18915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW30_18920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW30_18925	COG0768	penicillin binding
EXW30_18930	COG0768	penicillin binding
EXW30_18940	COG0275	rRNA processing
EXW30_18945	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW30_18950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW30_18955	COG0454	-acetyltransferase
EXW30_18965	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW30_18970	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW30_18975	COG1323	Belongs to the UPF0348 family
EXW30_18980	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW30_18985	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW30_18990	COG3314	Sporulation integral membrane protein YlbJ
EXW30_19000	COG0742	ribosomal rna small subunit methyltransferase
EXW30_19010	COG4471	UPF0298 protein
EXW30_19015	COG3679	Belongs to the UPF0342 family
EXW30_19020	COG0406	alpha-ribazole phosphatase activity
EXW30_19035	COG2340	Cysteine-rich secretory protein family
EXW30_19045	COG3336	cytochrome c oxidase
EXW30_19070	COG0109	protoheme IX farnesyltransferase activity
EXW30_19075	COG1612	heme a metabolic process
EXW30_19080	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW30_19090	COG0772	Belongs to the SEDS family
EXW30_19095	COG4838	Belongs to the UPF0358 family
EXW30_19100	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW30_19105	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW30_19115	COG4896	Protein conserved in bacteria
EXW30_19130	COG1217	gtp-binding protein TYPA
EXW30_19140	COG0483	inositol monophosphate 1-phosphatase activity
EXW30_19150	COG4493	Belongs to the UPF0637 family
EXW30_19155	COG4476	Belongs to the UPF0223 family
EXW30_19160	COG1982	Orn Lys Arg decarboxylase major
EXW30_19210	COG0022	dehydrogenase e1 component
EXW30_19215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW30_19230	COG0561	phosphatase activity
EXW30_19240	COG5503	Protein of unknown function (DUF1447)
EXW30_19245	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW30_19250	COG0569	domain protein
EXW30_19260	COG1473	amidohydrolase
EXW30_19265	COG2171	N-acyltransferase activity
EXW30_19270	COG0583	DNA-binding transcription factor activity
EXW30_19275	COG0517	IMP dehydrogenase activity
EXW30_19285	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW30_19290	COG4703	Protein of unknown function (DUF1797)
EXW30_19305	COG2200	EAL domain
EXW30_19310	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_19315	COG1408	metallophosphoesterase
EXW30_19360	COG2814	Major facilitator Superfamily
EXW30_19370	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW30_19380	COG3209	COG3209 Rhs family protein
EXW30_19390	COG2205	protein histidine kinase activity
EXW30_19400	COG0436	Aminotransferase
EXW30_19405	COG1609	Transcriptional regulator
EXW30_19410	COG3833	ABC-type maltose transport systems, permease component
EXW30_19415	COG1175	transmembrane transport
EXW30_19420	COG2182	Extracellular solute-binding protein
EXW30_19430	COG0366	Alpha amylase catalytic
EXW30_19435	COG3842	ATPase activity
EXW30_19440	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_19480	COG0183	Belongs to the thiolase family
EXW30_19515	COG1695	Transcriptional regulator
EXW30_19520	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_19530	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW30_19545	COG3344	reverse transcriptase
EXW30_19550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW30_19555	COG0436	Aminotransferase
EXW30_19560	COG1850	ribulose-bisphosphate carboxylase activity
EXW30_19565	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW30_19570	COG0235	Class ii aldolase
EXW30_19575	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW30_19590	COG2084	Dehydrogenase
EXW30_19600	COG2199	diguanylate cyclase activity
EXW30_19605	COG0778	Nitroreductase
EXW30_19630	COG1263	PTS System
EXW30_19630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW30_19630	COG2190	(PTS) system
EXW30_19635	COG3711	transcriptional antiterminator
EXW30_19645	COG2188	Transcriptional regulator
EXW30_19650	COG0363	glucosamine-6-phosphate deaminase activity
EXW30_19655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW30_19665	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW30_19675	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW30_19685	COG1547	Domain of unknown function (DUF309)
EXW30_19695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW30_19700	COG4086	secreted protein
EXW30_19705	COG0561	phosphatase activity
EXW30_19710	COG0697	spore germination
EXW30_19725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW30_19765	COG1686	Belongs to the peptidase S11 family
EXW30_19775	COG1725	Transcriptional regulator
EXW30_19780	COG1131	(ABC) transporter
EXW30_19800	COG1846	Transcriptional regulator
EXW30_19815	COG0598	Magnesium transport protein CorA
EXW30_19830	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW30_19840	COG4974	Belongs to the 'phage' integrase family
EXW30_19850	COG0735	belongs to the Fur family
EXW30_19855	COG1300	Membrane
EXW30_19875	COG0667	Aldo Keto reductase
EXW30_19880	COG0656	L-ascorbic acid biosynthetic process
EXW30_19885	COG0456	acetyltransferase
EXW30_19885	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW30_19895	COG0737	Belongs to the 5'-nucleotidase family
EXW30_19895	COG1525	nuclease
EXW30_19895	COG4085	toxin activity
EXW30_19900	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW30_19910	COG0596	Alpha beta hydrolase
EXW30_19915	COG2056	Na+-H+ antiporter family
EXW30_19920	COG1609	Transcriptional regulator
EXW30_19925	COG0456	acetyltransferase
EXW30_19930	COG1073	alpha beta
EXW30_19945	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW30_19945	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW30_19950	COG0307	riboflavin synthase, alpha
EXW30_19955	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW30_19955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW30_19970	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW30_19980	COG1073	alpha beta
EXW30_19980	COG2226	methyltransferase
EXW30_19985	COG0156	8-amino-7-oxononanoate synthase activity
EXW30_19995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW30_20005	COG1757	Na H antiporter
EXW30_20010	COG0737	Belongs to the 5'-nucleotidase family
EXW30_20020	COG1522	sequence-specific DNA binding
EXW30_20055	COG5444	nuclease activity
EXW30_20070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW30_20080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW30_20090	COG0300	oxidoreductase activity
EXW30_20095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW30_20100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW30_20105	COG1760	l-serine dehydratase
EXW30_20110	COG1760	l-serine dehydratase
EXW30_20120	COG1234	tRNA 3'-trailer cleavage
EXW30_20155	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW30_20160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW30_20170	COG1376	ErfK ybiS ycfS ynhG family protein
EXW30_20175	COG4129	membrane
EXW30_20180	COG1126	abc transporter atp-binding protein
EXW30_20185	COG0765	amino acid transport
EXW30_20190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW30_20200	COG2816	NAD+ diphosphatase activity
EXW30_20205	COG2323	membrane
EXW30_20210	COG0772	Belongs to the SEDS family
EXW30_20215	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW30_20220	COG0022	dehydrogenase e1 component
EXW30_20225	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW30_20230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW30_20245	COG0280	phosphate acetyltransferase
EXW30_20255	COG3290	protein histidine kinase activity
EXW30_20255	COG3829	transcription factor binding
EXW30_20275	COG0584	glycerophosphoryl diester phosphodiesterase
EXW30_20280	COG3093	addiction module antidote protein HigA
EXW30_20355	COG0745	RESPONSE REGULATOR receiver
EXW30_20365	COG0750	zinc metalloprotease
EXW30_20370	COG0497	DNA recombination
EXW30_20375	COG1438	arginine binding
EXW30_20380	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW30_20385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW30_20390	COG0142	geranyltranstransferase activity
EXW30_20395	COG1722	exodeoxyribonuclease VII activity
EXW30_20405	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW30_20410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW30_20415	COG1302	Protein conserved in bacteria
EXW30_20420	COG0439	Biotin carboxylase
EXW30_20425	COG0511	ligase activity, forming carbon-carbon bonds
EXW30_20470	COG3854	ATPases associated with a variety of cellular activities
EXW30_20490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW30_20495	COG0006	proline dipeptidase activity
EXW30_20510	COG3872	metal-dependent enzyme
EXW30_20520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW30_20545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW30_20555	COG1609	Transcriptional regulator
EXW30_20565	COG2076	Multidrug Resistance protein
EXW30_20570	COG2076	Multidrug Resistance protein
EXW30_20610	COG1725	Transcriptional regulator
EXW30_20625	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW30_20630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW30_20635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW30_20640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW30_20670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW30_20695	COG4970	Tfp pilus assembly protein FimT
EXW30_20700	COG4537	Required for transformation and DNA binding
EXW30_20705	COG1459	type II secretion system
EXW30_20710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW30_20775	COG1410	methionine synthase
EXW30_20775	COG0646	methionine synthase
EXW30_20780	COG0646	methionine synthase
EXW30_20780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW30_20785	COG0626	cystathionine gamma-synthase activity
EXW30_20790	COG0626	cystathionine gamma-synthase activity
EXW30_20810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW30_20820	COG1940	carbohydrate kinase activity
EXW30_20825	COG4483	Protein conserved in bacteria
EXW30_20830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW30_20835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW30_20840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW30_20845	COG0704	Plays a role in the regulation of phosphate uptake
EXW30_20855	COG0581	inorganic phosphate transmembrane transporter activity
EXW30_20860	COG0573	inorganic phosphate transmembrane transporter activity
EXW30_20865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW30_20870	COG0768	penicillin binding
EXW30_20875	COG0477	Major facilitator Superfamily
EXW30_20880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW30_20900	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW30_20905	COG0735	belongs to the Fur family
EXW30_20910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW30_20915	COG1121	(ABC) transporter
EXW30_20920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW30_20930	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW30_20950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW30_20955	COG2384	SAM-dependent methyltransferase
EXW30_20960	COG2010	Cytochrome c
EXW30_20965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW30_20970	COG0358	DNA primase activity
EXW30_20980	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW30_20985	COG0517	IMP dehydrogenase activity
EXW30_20990	COG1381	Involved in DNA repair and RecF pathway recombination
EXW30_21000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW30_21005	COG0295	cytidine deaminase activity
EXW30_21010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW30_21015	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW30_21020	COG1480	7TM receptor with intracellular HD hydrolase
EXW30_21025	COG1702	phosphate starvation-inducible protein PhoH
EXW30_21040	COG1610	YqeY-like protein
EXW30_21045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW30_21050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW30_21055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW30_21065	COG0484	heat shock protein binding
EXW30_21070	COG0443	Heat shock 70 kDa protein
EXW30_21080	COG1420	regulation of RNA biosynthetic process
EXW30_21085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW30_21090	COG1733	regulation of RNA biosynthetic process
EXW30_21095	COG0481	GTPase activity
EXW30_21105	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW30_21110	COG0268	Binds directly to 16S ribosomal RNA
EXW30_21115	COG1466	dna polymerase III delta subunit
EXW30_21125	COG2333	competence protein COMEC
EXW30_21125	COG0658	competence protein
EXW30_21130	COG2131	deaminase
EXW30_21135	COG1555	photosystem II stabilization
EXW30_21135	COG1596	polysaccharide export
EXW30_21140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW30_21145	COG2226	methyltransferase
EXW30_21150	COG0799	negative regulation of ribosome biogenesis
EXW30_21155	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW30_21160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW30_21165	COG1534	Rna-binding protein
EXW30_21170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW30_21175	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW30_21180	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW30_21190	COG0688	phosphatidylethanolamine metabolic process
EXW30_21210	COG2357	RelA SpoT domain protein
EXW30_21220	COG1785	Belongs to the alkaline phosphatase family
EXW30_21230	COG2267	carboxylic ester hydrolase activity
EXW30_21265	COG1404	Belongs to the peptidase S8 family
EXW30_21270	COG3186	Phenylalanine-4-hydroxylase
EXW30_21280	COG2514	catechol 2,3-dioxygenase activity
EXW30_21285	COG2259	Doxx family
EXW30_21325	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW30_21340	COG1454	alcohol dehydrogenase
EXW30_21340	COG1012	belongs to the aldehyde dehydrogenase family
EXW30_21345	COG0626	cystathionine gamma-synthase activity
EXW30_21350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW30_21355	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW30_21360	COG2226	methyltransferase
EXW30_21375	COG0768	penicillin binding
EXW30_21385	COG0572	uridine kinase
EXW30_21390	COG0826	peptidase U32
EXW30_21395	COG0826	peptidase U32
EXW30_21400	COG4122	O-methyltransferase activity
EXW30_21405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW30_21415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW30_21425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW30_21430	COG0628	permease
EXW30_21450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW30_21460	COG0482	sulfurtransferase activity
EXW30_21465	COG1104	cysteine desulfurase activity
EXW30_21470	COG1959	2 iron, 2 sulfur cluster binding
EXW30_21475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW30_21485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW30_21490	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW30_21500	COG1490	D-aminoacyl-tRNA deacylase activity
EXW30_21505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW30_21510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW30_21515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW30_21515	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW30_21520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW30_21525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW30_21525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW30_21535	COG2244	polysaccharide biosynthetic process
EXW30_21540	COG2323	membrane
EXW30_21555	COG1862	Preprotein translocase
EXW30_21560	COG0343	queuine tRNA-ribosyltransferase activity
EXW30_21575	COG2255	four-way junction helicase activity
EXW30_21580	COG0632	four-way junction helicase activity
EXW30_21585	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW30_21610	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW30_21615	COG0157	Belongs to the NadC ModD family
EXW30_21620	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW30_21625	COG1104	cysteine desulfurase activity
EXW30_21630	COG1827	regulation of RNA biosynthetic process
EXW30_21635	COG2258	MOSC domain
EXW30_21640	COG0077	Prephenate dehydratase
EXW30_21645	COG0577	efflux transmembrane transporter activity
EXW30_21650	COG0577	efflux transmembrane transporter activity
EXW30_21655	COG1136	(ABC) transporter
EXW30_21660	COG5002	protein histidine kinase activity
EXW30_21665	COG0745	RESPONSE REGULATOR receiver
EXW30_21670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW30_21675	COG3290	protein histidine kinase activity
EXW30_21685	COG2868	ribosomal protein
EXW30_21695	COG1530	ribonuclease E activity
EXW30_21700	COG1994	Peptidase M50
EXW30_21705	COG0739	heme binding
EXW30_21710	COG2894	cell division
EXW30_21715	COG0850	regulation of cytokinetic process
EXW30_21730	COG1077	Cell shape determining protein MreB Mrl
EXW30_21735	COG2003	Belongs to the UPF0758 family
EXW30_21740	COG0424	maF-like protein
EXW30_21755	COG0285	dihydrofolate synthase activity
EXW30_21770	COG1388	LysM domain
EXW30_21775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW30_21780	COG0113	porphobilinogen synthase activity
EXW30_21785	COG1587	Uroporphyrinogen-III synthase
EXW30_21790	COG0181	hydroxymethylbilane synthase activity
EXW30_21795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW30_21800	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW30_21805	COG1846	Transcriptional regulator
EXW30_21810	COG1764	response to oxidative stress
EXW30_21815	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW30_21825	COG0470	DNA polymerase III
EXW30_21825	COG1067	ATP-dependent peptidase activity
EXW30_21835	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW30_21865	COG4974	Belongs to the 'phage' integrase family
EXW30_21880	COG0622	Phosphoesterase
EXW30_21890	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW30_21895	COG5401	PFAM Sporulation and spore germination
EXW30_21920	COG2197	response regulator
EXW30_21925	COG2233	PERMEase
EXW30_21930	COG0402	S-adenosylhomocysteine deaminase activity
EXW30_21935	COG1983	PspC domain protein
EXW30_21940	COG1396	sequence-specific DNA binding
EXW30_21945	COG0697	spore germination
EXW30_21955	COG1959	2 iron, 2 sulfur cluster binding
EXW30_21960	COG1668	transmembrane transport
EXW30_21965	COG4152	abc transporter atp-binding protein
EXW30_21970	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW30_21975	COG1360	Flagellar Motor Protein
EXW30_21980	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW30_21985	COG1876	peptidase activity
EXW30_21990	COG0824	Thioesterase
EXW30_21995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW30_22000	COG1053	succinate dehydrogenase
EXW30_22005	COG2009	succinate dehydrogenase
EXW30_22010	COG1719	4-vinyl reductase, 4VR
EXW30_22015	COG0322	excinuclease ABC activity
EXW30_22020	COG3118	belongs to the thioredoxin family
EXW30_22025	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW30_22030	COG2086	electron transfer activity
EXW30_22035	COG1024	Enoyl-CoA hydratase
EXW30_22040	COG1309	transcriptional regulator
EXW30_22045	COG0318	PFAM AMP-dependent synthetase and ligase
EXW30_22070	COG2318	DinB family
EXW30_22095	COG1131	(ABC) transporter
EXW30_22100	COG2205	protein histidine kinase activity
EXW30_22105	COG0745	RESPONSE REGULATOR receiver
EXW30_22110	COG4895	conserved protein (DUF2196)
EXW30_22115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW30_22125	COG4509	Sortase family
EXW30_22130	COG1120	ATPase activity
EXW30_22145	COG5386	Cell surface protein
EXW30_22155	COG5386	Cell surface protein
EXW30_22160	COG1114	Component of the transport system for branched-chain amino acids
EXW30_22165	COG1187	pseudouridine synthase activity
EXW30_22170	COG1193	negative regulation of DNA recombination
EXW30_22175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW30_22175	COG1796	DNA polymerase
EXW30_22180	COG1286	toxin biosynthetic process
EXW30_22185	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW30_22190	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW30_22215	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW30_22220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW30_22230	COG1418	mRNA catabolic process
EXW30_22250	COG2814	Major facilitator Superfamily
EXW30_22255	COG1566	PFAM secretion protein HlyD family protein
EXW30_22260	COG1309	transcriptional regulator
EXW30_22265	COG1363	Peptidase, m42
EXW30_22275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW30_22290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW30_22300	COG1484	DNA-dependent DNA replication
EXW30_22305	COG3611	Membrane attachment protein
EXW30_22310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW30_22315	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW30_22325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW30_22335	COG1971	Probably functions as a manganese efflux pump
EXW30_22345	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW30_22345	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW30_22350	COG5002	protein histidine kinase activity
EXW30_22355	COG0745	RESPONSE REGULATOR receiver
EXW30_22375	COG0538	isocitrate dehydrogenase activity
EXW30_22380	COG0372	Belongs to the citrate synthase family
EXW30_22395	COG0628	permease
EXW30_22400	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW30_22410	COG0205	6-phosphofructokinase activity
EXW30_22425	COG1725	Transcriptional regulator
EXW30_22430	COG0281	malic enzyme
EXW30_22435	COG0587	DNA-directed DNA polymerase activity
EXW30_22450	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW30_22470	COG4109	DRTGG domain
EXW30_22475	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW30_22480	COG0006	proline dipeptidase activity
EXW30_22530	COG1476	TRANSCRIPTIONal
EXW30_22545	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_22550	COG0589	response to stress
EXW30_22570	COG0165	Argininosuccinate lyase
EXW30_22575	COG0137	argininosuccinate synthase activity
EXW30_22590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW30_22605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW30_22610	COG0827	DNA restriction-modification system
EXW30_22615	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW30_22620	COG3874	Sporulation protein YtfJ
EXW30_22635	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW30_22645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW30_22660	COG1104	cysteine desulfurase activity
EXW30_22665	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW30_22680	COG1309	transcriptional regulator
EXW30_22685	COG1956	GAF domain-containing protein
EXW30_22690	COG0626	cystathionine gamma-synthase activity
EXW30_22695	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW30_22720	COG1595	DNA-templated transcription, initiation
EXW30_22730	COG0110	maltose O-acetyltransferase activity
EXW30_22740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW30_22745	COG0454	-acetyltransferase
EXW30_22750	COG0517	IMP dehydrogenase activity
EXW30_22755	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW30_22770	COG0745	RESPONSE REGULATOR receiver
EXW30_22775	COG5002	protein histidine kinase activity
EXW30_22780	COG0666	response to abiotic stimulus
EXW30_22790	COG1970	mechanosensitive ion channel activity
EXW30_22810	COG1609	Transcriptional regulator
EXW30_22815	COG4851	CamS sex pheromone cAM373 precursor
EXW30_22820	COG3118	belongs to the thioredoxin family
EXW30_22830	COG2309	aminopeptidase activity
EXW30_22855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW30_22865	COG1695	Transcriptional regulator
EXW30_22875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW30_22885	COG1674	ftsk spoiiie
EXW30_22900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW30_22905	COG4848	Belongs to the UPF0354 family
EXW30_22910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW30_22915	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW30_22920	COG1363	Peptidase, m42
EXW30_22930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW30_22935	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW30_22945	COG0510	thiamine kinase activity
EXW30_22950	COG1523	belongs to the glycosyl hydrolase 13 family
EXW30_22960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW30_22965	COG1349	DNA-binding transcription factor activity
EXW30_22970	COG1187	pseudouridine synthase activity
EXW30_22975	COG2244	polysaccharide biosynthetic process
EXW30_22980	COG2081	HI0933 family
EXW30_22985	COG2814	Major facilitator Superfamily
EXW30_22995	COG3832	glyoxalase III activity
EXW30_23020	COG1329	Transcriptional regulator
EXW30_23045	COG0314	molybdopterin synthase activity
EXW30_23050	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW30_23055	COG0303	'Molybdopterin
EXW30_23060	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW30_23065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW30_23070	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW30_23090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW30_23100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW30_23140	COG0495	leucyl-tRNA aminoacylation
EXW30_23145	COG2814	Major facilitator Superfamily
EXW30_23150	COG0475	glutathione-regulated potassium exporter activity
EXW30_23155	COG0490	domain, Protein
EXW30_23160	COG0582	viral genome integration into host DNA
EXW30_23175	COG1136	(ABC) transporter
EXW30_23190	COG1242	4 iron, 4 sulfur cluster binding
EXW30_23195	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW30_23200	COG1794	racemase activity, acting on amino acids and derivatives
EXW30_23225	COG2267	carboxylic ester hydrolase activity
EXW30_23230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW30_23235	COG0671	phosphoesterase, PA-phosphatase related
EXW30_23240	COG0438	transferase activity, transferring glycosyl groups
EXW30_23250	COG1404	Belongs to the peptidase S8 family
EXW30_23255	COG2197	response regulator
EXW30_23260	COG4585	Histidine kinase
EXW30_23265	COG0746	molybdenum cofactor guanylyltransferase activity
EXW30_23285	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW30_23290	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW30_23330	COG5002	protein histidine kinase activity
EXW30_23335	COG3852	Histidine kinase
EXW30_23340	COG0753	catalase activity
EXW30_23345	COG2267	carboxylic ester hydrolase activity
EXW30_23355	COG1368	sulfuric ester hydrolase activity
EXW30_23360	COG4895	conserved protein (DUF2196)
EXW30_23375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW30_23380	COG1116	anion transmembrane transporter activity
EXW30_23385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW30_23410	COG0494	nUDIX hydrolase
EXW30_23445	COG2723	6-phospho-beta-galactosidase activity
EXW30_23450	COG2723	6-phospho-beta-galactosidase activity
EXW30_23455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW30_23455	COG1263	PTS System
EXW30_23455	COG2190	(PTS) system
EXW30_23460	COG3711	transcriptional antiterminator
EXW30_23465	COG1854	S-ribosylhomocysteine lyase activity
EXW30_23475	COG0288	reversible hydration of carbon dioxide
EXW30_23480	COG1271	oxidase subunit
EXW30_23485	COG1294	oxidase, subunit
EXW30_23500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW30_23525	COG1842	Phage shock protein A
EXW30_23555	COG5002	protein histidine kinase activity
EXW30_23560	COG0745	RESPONSE REGULATOR receiver
EXW30_23585	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW30_23590	COG1597	lipid kinase activity
EXW30_23620	COG1136	(ABC) transporter
EXW30_23635	COG5002	protein histidine kinase activity
EXW30_23645	COG0586	Pfam SNARE associated Golgi protein
EXW30_23655	COG0577	efflux transmembrane transporter activity
EXW30_23660	COG1136	(ABC) transporter
EXW30_23665	COG2207	Transcriptional regulator
EXW30_23665	COG3708	Transcriptional regulator
EXW30_23685	COG1131	(ABC) transporter
EXW30_23690	COG5658	integral membrane protein
EXW30_23695	COG0640	Transcriptional regulator
EXW30_23700	COG0745	RESPONSE REGULATOR receiver
EXW30_23705	COG2205	protein histidine kinase activity
EXW30_23710	COG0577	efflux transmembrane transporter activity
EXW30_23715	COG0577	efflux transmembrane transporter activity
EXW30_23720	COG1136	(ABC) transporter
EXW30_23725	COG0577	efflux transmembrane transporter activity
EXW30_23740	COG2188	Transcriptional regulator
EXW30_23760	COG3964	amidohydrolase
EXW30_23780	COG4948	Mandelate Racemase Muconate Lactonizing
EXW30_23785	COG0318	PFAM AMP-dependent synthetase and ligase
EXW30_23790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW30_23795	COG0596	Alpha beta hydrolase
EXW30_23800	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW30_23805	COG1169	isochorismate synthase
EXW30_23810	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW30_23815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW30_23820	COG1278	Cold shock
EXW30_23835	COG1051	belongs to the nudix hydrolase family
EXW30_23850	COG0058	SHG alpha-glucan phosphorylase activity
EXW30_23860	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW30_23865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW30_23870	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW30_23880	COG3344	reverse transcriptase
EXW30_24010	COG1285	pathogenesis
EXW30_24015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW30_24025	COG0166	Belongs to the GPI family
EXW30_24035	COG2155	Conserved Protein
EXW30_24040	COG1098	S1 RNA binding domain
EXW30_24045	COG0436	Aminotransferase
EXW30_24050	COG1522	sequence-specific DNA binding
EXW30_24055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW30_24060	COG2267	carboxylic ester hydrolase activity
EXW30_24070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW30_24085	COG5018	Exonuclease
EXW30_24090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW30_24115	COG2050	protein possibly involved in aromatic compounds catabolism
EXW30_24125	COG1268	BioY protein
EXW30_24130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW30_24135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW30_24145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW30_24150	COG3584	3D domain protein
EXW30_24165	COG1252	NADH dehydrogenase
EXW30_24170	COG0492	ferredoxin-NADP+ reductase activity
EXW30_24175	COG3708	Transcriptional regulator
EXW30_24195	COG1683	Conserved Protein
EXW30_24205	COG0316	Belongs to the HesB IscA family
EXW30_24210	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW30_24215	COG4844	belongs to the
EXW30_24220	COG1252	NADH dehydrogenase
EXW30_24225	COG2274	protein secretion by the type I secretion system
EXW30_24230	COG0390	transport system, permease component
EXW30_24235	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW30_24265	COG4837	Protein of unknown function (DUF1462)
EXW30_24270	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW30_24280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW30_24285	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW30_24300	COG1136	(ABC) transporter
EXW30_24300	COG0577	efflux transmembrane transporter activity
EXW30_24305	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW30_24315	COG0647	UMP catabolic process
EXW30_24325	COG2445	Protein of unknown function DUF86
EXW30_24330	COG1494	fructose-1,6-bisphosphatase
EXW30_24355	COG4470	Protein conserved in bacteria
EXW30_24365	COG0789	Transcriptional regulator
EXW30_24370	COG4377	Putative membrane peptidase family (DUF2324)
EXW30_24395	COG0739	heme binding
EXW30_24405	COG3377	Domain of unknown function (DUF1805)
EXW30_24410	COG0737	Belongs to the 5'-nucleotidase family
EXW30_24420	COG0719	Fe-S assembly protein
EXW30_24425	COG0822	iron-sulfur transferase activity
EXW30_24430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW30_24435	COG0719	Fe-S assembly protein
EXW30_24440	COG0396	ATPase activity
EXW30_24445	COG1464	Belongs to the NlpA lipoprotein family
EXW30_24450	COG1464	Belongs to the NlpA lipoprotein family
EXW30_24455	COG2011	ABC-type metal ion transport system permease component
EXW30_24470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW30_24475	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW30_24480	COG0509	glycine decarboxylation via glycine cleavage system
EXW30_24485	COG1393	Belongs to the ArsC family
EXW30_24520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW30_24535	COG1960	acyl-CoA dehydrogenase activity
EXW30_24540	COG0183	Belongs to the thiolase family
EXW30_24545	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW30_24545	COG1024	Enoyl-CoA hydratase
EXW30_24555	COG1686	Belongs to the peptidase S11 family
EXW30_24560	COG0506	proline dehydrogenase activity
EXW30_24570	COG0011	TIGRFAM Protein of
EXW30_24575	COG0840	transmembrane signaling receptor activity
EXW30_24585	COG2814	Major facilitator Superfamily
EXW30_24590	COG0531	amino acid
EXW30_24610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW30_24645	COG0586	Pfam SNARE associated Golgi protein
EXW30_24655	COG1376	ErfK ybiS ycfS ynhG family protein
EXW30_24660	COG0745	RESPONSE REGULATOR receiver
EXW30_24665	COG5002	protein histidine kinase activity
EXW30_24685	COG0840	transmembrane signaling receptor activity
EXW30_24690	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW30_24695	COG3227	Zinc metalloprotease (Elastase)
EXW30_24700	COG1741	Belongs to the pirin family
EXW30_24715	COG0586	Pfam SNARE associated Golgi protein
EXW30_24720	COG0475	glutathione-regulated potassium exporter activity
EXW30_24725	COG0490	domain, Protein
EXW30_24730	COG1115	amino acid carrier protein
EXW30_24735	COG0783	Belongs to the Dps family
EXW30_24745	COG2318	DinB family
EXW30_24750	COG1611	Belongs to the LOG family
EXW30_24760	COG1528	Iron-storage protein
EXW30_24770	COG2311	Membrane
EXW30_24775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW30_24780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW30_24785	COG1115	amino acid carrier protein
EXW30_24790	COG2910	NAD(P)H-binding
EXW30_24800	COG0656	L-ascorbic acid biosynthetic process
EXW30_24805	COG2814	Major facilitator Superfamily
EXW30_24810	COG1733	regulation of RNA biosynthetic process
EXW30_24820	COG1252	NADH dehydrogenase
EXW30_24865	COG3655	Transcriptional regulator
EXW30_24880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW30_24910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW30_24930	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW30_24935	COG0557	exoribonuclease II activity
EXW30_24940	COG1647	Serine aminopeptidase, S33
EXW30_24945	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW30_24950	COG1346	cytolysis
EXW30_24975	COG0149	triose-phosphate isomerase activity
EXW30_24980	COG0126	phosphoglycerate kinase activity
EXW30_24985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW30_25000	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW30_25025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW30_25040	COG2323	membrane
EXW30_25050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW30_25055	COG1481	regulation of sporulation
EXW30_25060	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW30_25065	COG1660	Displays ATPase and GTPase activities
EXW30_25070	COG1051	belongs to the nudix hydrolase family
EXW30_25080	COG0492	ferredoxin-NADP+ reductase activity
EXW30_25085	COG0457	Tetratricopeptide repeat
EXW30_25090	COG0110	maltose O-acetyltransferase activity
EXW30_25095	COG0546	phosphoglycolate phosphatase activity
EXW30_25100	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW30_25105	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW30_25110	COG1950	PFAM Membrane protein of
EXW30_25120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW30_25135	COG0789	Transcriptional regulator
EXW30_25170	COG0583	DNA-binding transcription factor activity
EXW30_25175	COG0789	Transcriptional regulator
EXW30_25180	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW30_25185	COG0488	(ABC) transporter
EXW30_25195	COG1132	(ABC) transporter
EXW30_25200	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW30_25205	COG0583	DNA-binding transcription factor activity
EXW30_25210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW30_25215	COG0793	Belongs to the peptidase S41A family
EXW30_25215	COG3409	Peptidoglycan-binding domain 1 protein
EXW30_25220	COG2177	Part of the ABC transporter FtsEX involved in
EXW30_25225	COG2884	Cell division ATP-binding protein ftsE
EXW30_25265	COG1278	Cold shock
EXW30_25270	COG1040	competence protein
EXW30_25275	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW30_25280	COG1388	LysM domain
EXW30_25280	COG0791	NLP P60 protein
EXW30_25285	COG1733	regulation of RNA biosynthetic process
EXW30_25290	COG1307	EDD domain protein, DegV family
EXW30_25295	COG1739	Uncharacterized protein family UPF0029
EXW30_25300	COG1316	TRANSCRIPTIONal
EXW30_25305	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW30_25310	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW30_25315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW30_25325	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW30_25325	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW30_25345	COG1486	melibiose metabolic process
EXW30_25350	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW30_25355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW30_25365	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW30_25380	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW30_25390	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW30_25395	COG1301	dicarboxylic acid transport
EXW30_25410	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW30_25415	COG1271	oxidase subunit
EXW30_25420	COG1294	oxidase, subunit
EXW30_25425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW30_25430	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW30_25435	COG1620	l-lactate permease
EXW30_25445	COG2389	metal-binding protein
EXW30_25460	COG1368	sulfuric ester hydrolase activity
EXW30_25470	COG1388	LysM domain
EXW30_25470	COG0791	NLP P60 protein
EXW30_25475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW30_25485	COG1215	transferase activity, transferring glycosyl groups
EXW30_25490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW30_25500	COG1388	LysM domain
EXW30_25500	COG3584	3D domain protein
EXW30_25510	COG4715	Zinc finger, swim domain protein
EXW30_25515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW30_25560	COG0577	efflux transmembrane transporter activity
EXW30_25565	COG1136	(ABC) transporter
EXW30_25595	COG0745	RESPONSE REGULATOR receiver
EXW30_25600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW30_25615	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW30_25630	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW30_25650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW30_25665	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW30_25680	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW30_25690	COG0728	peptidoglycan biosynthetic process
EXW30_25710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW30_25715	COG2089	acid synthase
EXW30_25720	COG1083	cytidylyl-transferase
EXW30_25725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW30_25730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW30_25735	COG4464	protein tyrosine phosphatase activity
EXW30_25740	COG0489	protein tyrosine kinase activity
EXW30_25745	COG3944	biosynthesis protein
EXW30_25750	COG0489	protein tyrosine kinase activity
EXW30_25765	COG1609	Transcriptional regulator
EXW30_25775	COG0739	heme binding
EXW30_25790	COG4555	ABC transporter
EXW30_25795	COG2385	sporulation resulting in formation of a cellular spore
EXW30_25810	COG4836	Membrane
EXW30_25815	COG1007	ATP synthesis coupled electron transport
EXW30_25820	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW30_25825	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW30_25830	COG0713	ATP synthesis coupled electron transport
EXW30_25835	COG0839	Belongs to the complex I subunit 6 family
EXW30_25845	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW30_25850	COG0649	NAD binding
EXW30_25855	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW30_25860	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW30_25865	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW30_25870	COG5001	Diguanylate cyclase
EXW30_25870	COG3300	MHYT domain
EXW30_25885	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW30_25890	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW30_25895	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW30_25900	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW30_25910	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW30_25920	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW30_25955	COG0698	ribose 5-phosphate isomerase
EXW30_25965	COG2190	(PTS) system
EXW30_25970	COG2259	Doxx family
EXW30_25975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW30_25985	COG1971	Probably functions as a manganese efflux pump
EXW30_25990	COG0009	L-threonylcarbamoyladenylate synthase
EXW30_26005	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW30_26010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW30_26015	COG1435	thymidine kinase activity
EXW30_26025	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW30_26030	COG1494	fructose-1,6-bisphosphatase
EXW30_26050	COG4821	SIS domain
EXW30_26055	COG0504	CTP synthase activity
EXW30_26060	COG3343	RNA polymerase activity
EXW30_26070	COG1960	acyl-CoA dehydrogenase activity
EXW30_26075	COG1960	acyl-CoA dehydrogenase activity
EXW30_26080	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW30_26085	COG0183	Belongs to the thiolase family
EXW30_26090	COG0247	lactate metabolic process
EXW30_26090	COG2181	nitrate reductase activity
EXW30_26095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW30_26100	COG4294	response to UV
EXW30_26105	COG3300	MHYT domain
EXW30_26105	COG5001	Diguanylate cyclase
EXW30_26125	COG3227	Zinc metalloprotease (Elastase)
EXW30_26130	COG2197	response regulator
EXW30_26135	COG4585	Histidine kinase
EXW30_26140	COG0842	Transport permease protein
EXW30_26145	COG1131	(ABC) transporter
EXW30_26150	COG0024	Methionine aminopeptidase
EXW30_26155	COG2234	aminopeptidase activity
EXW30_26170	COG4506	Protein conserved in bacteria
EXW30_26175	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW30_26205	COG2814	Major facilitator Superfamily
EXW30_26210	COG0789	Transcriptional regulator
EXW30_26215	COG0584	glycerophosphoryl diester phosphodiesterase
EXW30_26220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW30_26230	COG1994	Peptidase M50
EXW30_26240	COG1078	dGTPase activity
EXW30_26245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW30_26250	COG1120	ATPase activity
EXW30_26255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW30_26260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW30_26265	COG4844	belongs to the
EXW30_26280	COG0280	phosphate acetyltransferase
EXW30_26285	COG3253	May function as heme-dependent peroxidase
EXW30_26295	COG3773	Cell wall hydrolase
EXW30_26305	COG2363	Small membrane protein
EXW30_26315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW30_26320	COG2233	PERMEase
EXW30_26325	COG0561	phosphatase activity
EXW30_26330	COG2814	Major facilitator Superfamily
EXW30_26335	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW30_26340	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW30_26345	COG1131	(ABC) transporter
EXW30_26350	COG2755	lipolytic protein G-D-S-L family
EXW30_26355	COG1609	Transcriptional regulator
EXW30_26365	COG0460	homoserine dehydrogenase
EXW30_26370	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW30_26375	COG2873	o-acetylhomoserine
EXW30_26385	COG1011	Hydrolase
EXW30_26390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW30_26400	COG2197	response regulator
EXW30_26405	COG4585	Histidine kinase
EXW30_26405	COG2203	Gaf domain
EXW30_26410	COG0351	phosphomethylpyrimidine kinase
EXW30_26415	COG3706	GGDEF domain
EXW30_26420	COG2879	small protein
EXW30_26425	COG1966	Carbon starvation protein
EXW30_26430	COG3279	Response regulator of the LytR AlgR family
EXW30_26435	COG0477	Major facilitator Superfamily
EXW30_26465	COG0840	transmembrane signaling receptor activity
EXW30_26475	COG1607	acyl-coa hydrolase
EXW30_26485	COG1216	Glycosyl transferase, family 2
EXW30_26490	COG0488	(ABC) transporter
EXW30_26505	COG0463	Glycosyl transferase, family 2
EXW30_26510	COG1309	transcriptional regulator
EXW30_26515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW30_26520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW30_26520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW30_26525	COG0628	permease
EXW30_26535	COG1380	Effector of murein hydrolase LrgA
EXW30_26540	COG3279	Response regulator of the LytR AlgR family
EXW30_26545	COG3275	phosphorelay sensor kinase activity
EXW30_26555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW30_26565	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW30_26615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW30_26620	COG1272	protein, Hemolysin III
EXW30_26645	COG1164	Oligoendopeptidase f
EXW30_26660	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW30_26670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW30_26675	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW30_26680	COG4853	Protein conserved in bacteria
EXW30_26690	COG5002	protein histidine kinase activity
EXW30_26695	COG0745	RESPONSE REGULATOR receiver
EXW30_26725	COG0305	Participates in initiation and elongation during chromosome replication
EXW30_26735	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW30_26740	COG4241	membrane
EXW30_26750	COG0629	single-stranded DNA binding
EXW30_26755	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW30_26760	COG0012	GTP binding
EXW30_26765	COG4481	Protein conserved in bacteria
EXW30_26770	COG0668	transmembrane transport
EXW30_26780	COG1475	DNA binding
EXW30_26785	COG1192	Involved in chromosome partitioning
EXW30_26790	COG1475	DNA binding
EXW30_26800	COG0445	tRNA wobble uridine modification
EXW30_26805	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW30_26810	COG1847	R3H domain protein
EXW30_26815	COG0706	membrane insertase activity
EXW30_26820	COG0594	ribonuclease P activity
EXW30_26825	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW30_26860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW30_26885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW30_26920	COG0561	phosphatase activity
EXW30_26930	COG1609	Transcriptional regulator
EXW30_26955	COG0494	nUDIX hydrolase
EXW30_26980	COG0739	heme binding
EXW30_26990	COG1595	DNA-templated transcription, initiation
EXW30_27010	COG2409	Drug exporters of the RND superfamily
EXW30_27080	COG0456	acetyltransferase
EXW30_27150	COG1278	Cold shock
EXW30_27175	COG2211	Major facilitator Superfamily
EXW30_27185	COG0582	viral genome integration into host DNA
EXW30_27230	COG0531	amino acid
EXW30_27240	COG3338	carbonate dehydratase activity
EXW30_27250	COG5002	protein histidine kinase activity
EXW30_27285	COG5002	protein histidine kinase activity
EXW30_27305	COG0583	DNA-binding transcription factor activity
EXW30_27310	COG1741	Belongs to the pirin family
EXW30_27315	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW30_27320	COG3227	Zinc metalloprotease (Elastase)
EXW30_27360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW30_27370	COG2707	UPF0756 membrane protein
EXW30_27380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW30_27385	COG4974	Belongs to the 'phage' integrase family
EXW30_27400	COG0583	DNA-binding transcription factor activity
EXW30_27405	COG4689	acetoacetate decarboxylase
EXW30_27430	COG0531	amino acid
EXW30_27445	COG2318	DinB family
EXW30_27450	COG2378	regulation of single-species biofilm formation
EXW30_27470	COG1309	transcriptional regulator
EXW30_27500	COG3739	integral membrane protein
EXW30_27505	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW30_27510	COG1131	(ABC) transporter
EXW30_27520	COG3655	Transcriptional regulator
EXW30_27540	COG3344	reverse transcriptase
EXW30_27570	COG1131	(ABC) transporter
EXW30_27590	COG0825	malonyl-CoA metabolic process
EXW30_27640	COG2814	Major facilitator Superfamily
EXW30_27645	COG0583	DNA-binding transcription factor activity
EXW30_27715	COG3493	citrate carrier protein
EXW30_27720	COG4565	transcriptional regulatory protein
EXW30_27725	COG3290	protein histidine kinase activity
EXW30_27735	COG0745	RESPONSE REGULATOR receiver
EXW30_27765	COG0753	catalase activity
EXW30_27925	COG1192	Involved in chromosome partitioning
EXW30_28010	COG3344	reverse transcriptase
EXW30_28040	COG3344	reverse transcriptase
EXW30_28045	COG0741	lytic transglycosylase activity
EXW30_28045	COG0791	NLP P60 protein
EXW30_28175	COG0494	nUDIX hydrolase
EXW30_28180	COG2264	protein methyltransferase activity
EXW30_28185	COG2002	toxin-antitoxin pair type II binding
EXW30_28245	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW30_28245	COG2755	lipolytic protein G-D-S-L family
EXW30_28290	COG0741	lytic transglycosylase activity
EXW30_28345	COG0577	efflux transmembrane transporter activity
EXW30_28345	COG1136	(ABC) transporter
EXW30_28375	COG0582	viral genome integration into host DNA
EXW30_28430	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EXW30_28470	COG1609	Transcriptional regulator
EXW30_28475	COG2814	Major facilitator Superfamily
EXW30_28485	COG0673	inositol 2-dehydrogenase activity
EXW30_28510	COG1609	Transcriptional regulator
EXW30_28520	COG3718	enzyme involved in inositol metabolism
EXW30_28560	COG1923	regulation of RNA biosynthetic process
EXW30_28565	COG2868	ribosomal protein
EXW30_28570	COG3344	reverse transcriptase
EXW30_28595	COG0789	Transcriptional regulator
EXW30_28690	COG5002	protein histidine kinase activity
EXW30_28775	COG1819	glycosyl
EXW30_28780	COG0156	8-amino-7-oxononanoate synthase activity
EXW30_28785	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW30_28790	COG1136	(ABC) transporter
EXW30_28855	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW30_28880	COG0577	efflux transmembrane transporter activity
EXW30_28885	COG1136	(ABC) transporter
EXW30_28900	COG1396	sequence-specific DNA binding
EXW30_28905	COG0006	proline dipeptidase activity
EXW30_28915	COG0457	Tetratricopeptide repeat
EXW30_28985	COG1073	alpha beta
EXW30_29010	COG1876	peptidase activity
EXW30_29045	COG4974	Belongs to the 'phage' integrase family
EXW30_29130	COG0814	amino acid
EXW30_29135	COG1760	l-serine dehydratase
EXW30_29140	COG1760	l-serine dehydratase
EXW30_29145	COG1476	TRANSCRIPTIONal
EXW30_29160	COG2720	vancomycin resistance protein
EXW30_29180	COG1073	alpha beta
EXW30_29200	COG2318	DinB family
EXW30_29220	COG1309	transcriptional regulator
EXW30_29285	COG2205	protein histidine kinase activity
EXW30_29290	COG0745	RESPONSE REGULATOR receiver
EXW30_29420	COG0686	Belongs to the AlaDH PNT family
EXW30_29425	COG2508	Transcriptional regulator
EXW30_29425	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW30_29440	COG2814	Major facilitator Superfamily
EXW30_29445	COG1309	transcriptional regulator
EXW30_29455	COG0582	viral genome integration into host DNA
EXW30_29490	COG2814	Major facilitator Superfamily
EXW30_29495	COG1846	Transcriptional regulator
EXW30_29510	COG3344	reverse transcriptase
EXW30_29525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW30_29530	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW30_29560	COG1329	Transcriptional regulator
EXW30_29620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW30_29625	COG1011	Hydrolase
EXW30_29645	COG1028	Short-chain dehydrogenase reductase Sdr
EXW30_29670	COG0814	amino acid
EXW30_29675	COG0697	spore germination
EXW30_29835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released