locus-tag	class	description
EXW37_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW37_00010	COG0592	DNA-directed DNA polymerase activity
EXW37_00015	COG2501	S4 domain
EXW37_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW37_00025	COG0187	DNA topoisomerase II activity
EXW37_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW37_00065	COG0517	IMP dehydrogenase activity
EXW37_00065	COG0516	GMP reductase activity
EXW37_00070	COG1686	Belongs to the peptidase S11 family
EXW37_00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW37_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW37_00100	COG1428	Deoxynucleoside kinase
EXW37_00105	COG1428	Deoxynucleoside kinase
EXW37_00110	COG1335	isochorismatase
EXW37_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW37_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW37_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW37_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW37_00180	COG1982	Orn Lys Arg decarboxylase major
EXW37_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW37_00190	COG0470	DNA polymerase III
EXW37_00195	COG1774	PSP1 C-terminal conserved region
EXW37_00200	COG4467	Involved in initiation control of chromosome replication
EXW37_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW37_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW37_00220	COG2002	toxin-antitoxin pair type II binding
EXW37_00230	COG0084	hydrolase, TatD family'
EXW37_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW37_00250	COG4466	Protein conserved in bacteria
EXW37_00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW37_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW37_00270	COG0251	oxidation-reduction process
EXW37_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW37_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW37_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW37_00305	COG2002	toxin-antitoxin pair type II binding
EXW37_00310	COG2244	polysaccharide biosynthetic process
EXW37_00315	COG3956	TIGRFAM MazG family protein
EXW37_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW37_00340	COG1098	S1 RNA binding domain
EXW37_00355	COG2208	phosphoserine phosphatase activity
EXW37_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW37_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW37_00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW37_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW37_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW37_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW37_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW37_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW37_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW37_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW37_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW37_00420	COG1396	sequence-specific DNA binding
EXW37_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW37_00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW37_00520	COG3880	PFAM UvrB UvrC protein
EXW37_00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW37_00530	COG0542	response to heat
EXW37_00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW37_00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW37_00545	COG4956	integral membrane protein (PIN domain superfamily)
EXW37_00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW37_00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW37_00565	COG1045	serine acetyltransferase
EXW37_00570	COG0215	cysteine-tRNA ligase activity
EXW37_00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW37_00585	COG3688	RNA-binding protein containing a PIN domain
EXW37_00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW37_00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW37_00605	COG0250	Participates in transcription elongation, termination and antitermination
EXW37_00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW37_00615	COG0081	regulation of translation
EXW37_00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW37_00625	COG0222	ribosome binding
EXW37_00630	COG2813	Specifically methylates the guanine in position
EXW37_00635	COG0085	RNA polymerase activity
EXW37_00640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW37_00645	COG1358	cellular component organization or biogenesis
EXW37_00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW37_00660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW37_00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW37_00670	COG0051	transcription antitermination factor activity, RNA binding
EXW37_00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW37_00680	COG0088	Forms part of the polypeptide exit tunnel
EXW37_00685	COG0089	rRNA binding
EXW37_00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW37_00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW37_00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW37_00715	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW37_00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW37_00730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW37_00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW37_00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW37_00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW37_00765	COG1841	ribosomal large subunit assembly
EXW37_00770	COG0200	Binds to the 23S rRNA
EXW37_00775	COG0201	protein transport
EXW37_00780	COG0563	adenylate kinase activity
EXW37_00785	COG0024	Methionine aminopeptidase
EXW37_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW37_00800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW37_00805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW37_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW37_00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW37_00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW37_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW37_00860	COG0489	protein tyrosine kinase activity
EXW37_00870	COG2194	sulfuric ester hydrolase activity
EXW37_00875	COG0726	polysaccharide deacetylase
EXW37_00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW37_00960	COG4856	YbbR-like protein
EXW37_00965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW37_01010	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_01015	COG2011	ABC-type metal ion transport system permease component
EXW37_01025	COG1464	Belongs to the NlpA lipoprotein family
EXW37_01040	COG0277	FAD linked oxidase domain protein
EXW37_01045	COG2271	Major facilitator Superfamily
EXW37_01055	COG2814	Major facilitator Superfamily
EXW37_01075	COG0601	transmembrane transport
EXW37_01080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW37_01085	COG0444	Belongs to the ABC transporter superfamily
EXW37_01090	COG4608	Belongs to the ABC transporter superfamily
EXW37_01095	COG4166	transmembrane transport
EXW37_01105	COG2207	Transcriptional regulator
EXW37_01120	COG4166	transmembrane transport
EXW37_01125	COG4166	transmembrane transport
EXW37_01130	COG0656	L-ascorbic acid biosynthetic process
EXW37_01135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW37_01150	COG4149	molybdate abc transporter
EXW37_01155	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW37_01160	COG1910	domain protein
EXW37_01175	COG0697	spore germination
EXW37_01190	COG0204	Acyl-transferase
EXW37_01200	COG1609	Transcriptional regulator
EXW37_01210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW37_01225	COG5298	Protein conserved in bacteria
EXW37_01250	COG0488	(ABC) transporter
EXW37_01260	COG0747	negative chemotaxis
EXW37_01270	COG0601	transmembrane transport
EXW37_01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW37_01280	COG0444	Belongs to the ABC transporter superfamily
EXW37_01285	COG4608	Belongs to the ABC transporter superfamily
EXW37_01290	COG0561	phosphatase activity
EXW37_01320	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW37_01325	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW37_01335	COG0531	amino acid
EXW37_01340	COG2814	Major facilitator Superfamily
EXW37_01350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW37_01360	COG4294	response to UV
EXW37_01365	COG0705	Rhomboid family
EXW37_01370	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW37_01375	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW37_01380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW37_01385	COG0864	Transcriptional regulator
EXW37_01390	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW37_01395	COG2183	response to ionizing radiation
EXW37_01495	COG0802	atpase or kinase
EXW37_01500	COG1214	PFAM Peptidase M22, glycoprotease
EXW37_01505	COG0456	acetyltransferase
EXW37_01515	COG0488	(ABC) transporter
EXW37_01520	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW37_01530	COG1266	CAAX protease self-immunity
EXW37_01535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW37_01540	COG0459	protein refolding
EXW37_01545	COG0519	Catalyzes the synthesis of GMP from XMP
EXW37_01545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW37_01550	COG2252	PERMEase
EXW37_01560	COG5002	protein histidine kinase activity
EXW37_01585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW37_01610	COG0693	protein deglycase activity
EXW37_01650	COG4187	Peptidase family M20/M25/M40
EXW37_01670	COG2205	protein histidine kinase activity
EXW37_01675	COG0745	RESPONSE REGULATOR receiver
EXW37_01700	COG0697	spore germination
EXW37_01725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW37_01730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW37_01735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW37_01740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW37_01745	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW37_01750	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW37_01755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW37_01760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW37_01765	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW37_01770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW37_01775	COG0138	bifunctional purine biosynthesis protein purh
EXW37_01785	COG0151	Belongs to the GarS family
EXW37_01810	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW37_01815	COG0210	DNA helicase
EXW37_01820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW37_01825	COG4851	CamS sex pheromone cAM373 precursor
EXW37_01835	COG1012	belongs to the aldehyde dehydrogenase family
EXW37_01840	COG1335	isochorismatase
EXW37_01850	COG2011	ABC-type metal ion transport system permease component
EXW37_01855	COG1464	Belongs to the NlpA lipoprotein family
EXW37_01870	COG0003	Pfam Anion-transporting ATPase
EXW37_01875	COG1846	Transcriptional regulator
EXW37_01880	COG4682	membrane
EXW37_01890	COG0154	amidase activity
EXW37_01895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW37_01900	COG1597	lipid kinase activity
EXW37_01905	COG0546	phosphoglycolate phosphatase activity
EXW37_01910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW37_01920	COG1012	belongs to the aldehyde dehydrogenase family
EXW37_01925	COG2076	Multidrug Resistance protein
EXW37_01930	COG2309	aminopeptidase activity
EXW37_01945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW37_01955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW37_01960	COG5002	protein histidine kinase activity
EXW37_01965	COG4807	Protein conserved in bacteria
EXW37_01990	COG1757	Na H antiporter
EXW37_01995	COG1473	amidohydrolase
EXW37_02015	COG0450	alkyl hydroperoxide reductase
EXW37_02025	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW37_02035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW37_02040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW37_02045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW37_02050	COG0492	ferredoxin-NADP+ reductase activity
EXW37_02060	COG0166	Belongs to the GPI family
EXW37_02085	COG5002	protein histidine kinase activity
EXW37_02105	COG3541	Predicted nucleotidyltransferase
EXW37_02110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW37_02110	COG0723	plastoquinol--plastocyanin reductase activity
EXW37_02120	COG0765	amino acid transport
EXW37_02125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW37_02135	COG0840	transmembrane signaling receptor activity
EXW37_02160	COG0549	Belongs to the carbamate kinase family
EXW37_02175	COG0277	FAD linked oxidase domain protein
EXW37_02180	COG0366	Alpha amylase catalytic
EXW37_02185	COG2190	(PTS) system
EXW37_02185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW37_02185	COG1263	PTS System
EXW37_02205	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW37_02215	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW37_02235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW37_02240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW37_02245	COG1116	anion transmembrane transporter activity
EXW37_02250	COG0488	(ABC) transporter
EXW37_02295	COG2270	Major facilitator Superfamily
EXW37_02325	COG2310	stress, protein
EXW37_02330	COG2310	stress, protein
EXW37_02335	COG2310	stress, protein
EXW37_02340	COG0861	Integral membrane protein TerC family
EXW37_02350	COG3853	Toxic anion resistance protein (TelA)
EXW37_02360	COG4840	Belongs to the UPF0435 family
EXW37_02375	COG1295	ribonuclease BN
EXW37_02380	COG2217	Heavy metal translocating P-type atpase
EXW37_02385	COG0697	spore germination
EXW37_02410	COG0586	Pfam SNARE associated Golgi protein
EXW37_02425	COG3871	stress protein (general stress protein 26)
EXW37_02430	COG0387	Pfam Sodium calcium exchanger
EXW37_02440	COG0535	radical SAM domain protein
EXW37_02460	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW37_02480	COG3829	transcription factor binding
EXW37_02490	COG0833	amino acid
EXW37_02495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW37_02515	COG2066	Belongs to the glutaminase family
EXW37_02525	COG1263	PTS System
EXW37_02525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW37_02530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW37_02545	COG1216	Glycosyl transferase, family 2
EXW37_02555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW37_02555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW37_02560	COG0463	Glycosyl transferase, family 2
EXW37_02575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW37_02580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW37_02595	COG1228	amidohydrolase
EXW37_02600	COG1090	epimerase
EXW37_02605	COG2137	regulation of response to DNA damage stimulus
EXW37_02630	COG1988	membrane-bound metal-dependent
EXW37_02635	COG1194	a g-specific adenine glycosylase
EXW37_02655	COG3557	Belongs to the UPF0374 family
EXW37_02660	COG1132	(ABC) transporter
EXW37_02665	COG4129	membrane
EXW37_02675	COG0067	glutamate synthase
EXW37_02675	COG0069	glutamate synthase activity
EXW37_02675	COG0070	glutamate synthase
EXW37_02680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW37_02685	COG4555	ABC transporter
EXW37_02705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW37_02710	COG0735	belongs to the Fur family
EXW37_02830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW37_02835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW37_02855	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW37_02865	COG2766	serine protein kinase
EXW37_02870	COG2718	Belongs to the UPF0229 family
EXW37_02875	COG0494	nUDIX hydrolase
EXW37_02880	COG0673	inositol 2-dehydrogenase activity
EXW37_02885	COG2091	lysine biosynthetic process via aminoadipic acid
EXW37_02945	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW37_02950	COG2268	Band 7 protein
EXW37_02965	COG3290	protein histidine kinase activity
EXW37_02970	COG4565	transcriptional regulatory protein
EXW37_02975	COG2851	Citrate transporter
EXW37_03000	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW37_03005	COG3842	ATPase activity
EXW37_03010	COG1175	transmembrane transport
EXW37_03015	COG0395	ABC-type sugar transport system, permease component
EXW37_03025	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW37_03030	COG0745	RESPONSE REGULATOR receiver
EXW37_03035	COG5002	protein histidine kinase activity
EXW37_03045	COG4990	cell redox homeostasis
EXW37_03055	COG3290	protein histidine kinase activity
EXW37_03060	COG4565	transcriptional regulatory protein
EXW37_03065	COG3493	citrate carrier protein
EXW37_03070	COG0281	malic enzyme
EXW37_03080	COG0697	spore germination
EXW37_03085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW37_03095	COG5002	protein histidine kinase activity
EXW37_03100	COG0745	RESPONSE REGULATOR receiver
EXW37_03105	COG0456	acetyltransferase
EXW37_03110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW37_03115	COG3383	formate dehydrogenase (NAD+) activity
EXW37_03120	COG2427	Protein of unknown function (DUF1641)
EXW37_03135	COG0531	amino acid
EXW37_03145	COG0640	Transcriptional regulator
EXW37_03150	COG2217	Heavy metal translocating P-type atpase
EXW37_03155	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW37_03165	COG3227	Zinc metalloprotease (Elastase)
EXW37_03185	COG2720	vancomycin resistance protein
EXW37_03190	COG1316	TRANSCRIPTIONal
EXW37_03195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW37_03200	COG0346	lactoylglutathione lyase activity
EXW37_03205	COG1253	flavin adenine dinucleotide binding
EXW37_03210	COG1027	Aspartate ammonia-lyase
EXW37_03215	COG1620	l-lactate permease
EXW37_03220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW37_03240	COG3104	oligopeptide transport
EXW37_03245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW37_03250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW37_03255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW37_03270	COG0156	8-amino-7-oxononanoate synthase activity
EXW37_03275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW37_03285	COG4548	von Willebrand factor, type A
EXW37_03290	COG0714	Associated with various cellular activities
EXW37_03310	COG0531	amino acid
EXW37_03315	COG2188	Transcriptional regulator
EXW37_03320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW37_03320	COG1263	PTS System
EXW37_03325	COG0366	Alpha amylase catalytic
EXW37_03355	COG1115	amino acid carrier protein
EXW37_03360	COG1126	abc transporter atp-binding protein
EXW37_03365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW37_03370	COG0765	amino acid transport
EXW37_03375	COG0765	amino acid transport
EXW37_03380	COG0833	amino acid
EXW37_03405	COG2378	regulation of single-species biofilm formation
EXW37_03410	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW37_03415	COG5002	protein histidine kinase activity
EXW37_03430	COG0659	secondary active sulfate transmembrane transporter activity
EXW37_03455	COG0601	transmembrane transport
EXW37_03460	COG4608	Belongs to the ABC transporter superfamily
EXW37_03470	COG2271	Major facilitator Superfamily
EXW37_03475	COG1846	Transcriptional regulator
EXW37_03480	COG0477	Major facilitator Superfamily
EXW37_03485	COG1609	Transcriptional regulator
EXW37_03490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW37_03495	COG1869	D-ribose catabolic process
EXW37_03505	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW37_03510	COG1879	ABC-type sugar transport system periplasmic component
EXW37_03540	COG1063	alcohol dehydrogenase
EXW37_03585	COG0840	transmembrane signaling receptor activity
EXW37_03590	COG3584	3D domain protein
EXW37_03590	COG3583	domain protein
EXW37_03595	COG1476	TRANSCRIPTIONal
EXW37_03615	COG3104	oligopeptide transport
EXW37_03620	COG1114	Component of the transport system for branched-chain amino acids
EXW37_03635	COG1113	amino acid transport
EXW37_03640	COG2252	PERMEase
EXW37_03645	COG3620	sequence-specific DNA binding
EXW37_03665	COG0569	domain protein
EXW37_03665	COG0475	glutathione-regulated potassium exporter activity
EXW37_03680	COG1845	cytochrome c oxidase, subunit III
EXW37_03685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW37_03695	COG0833	amino acid
EXW37_03700	COG4990	cell redox homeostasis
EXW37_03715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW37_03720	COG0697	spore germination
EXW37_03725	COG0531	amino acid
EXW37_03735	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW37_03740	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW37_03750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW37_03755	COG0573	inorganic phosphate transmembrane transporter activity
EXW37_03760	COG0581	inorganic phosphate transmembrane transporter activity
EXW37_03770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW37_03890	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW37_03910	COG4991	sh3 domain protein
EXW37_03910	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW37_03910	COG3103	Sh3 type 3 domain protein
EXW37_03915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW37_03920	COG1116	anion transmembrane transporter activity
EXW37_03925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW37_03930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW37_03935	COG0352	thiamine-phosphate diphosphorylase activity
EXW37_03940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW37_03945	COG2104	thiamine diphosphate biosynthetic process
EXW37_03950	COG2022	thiamine diphosphate biosynthetic process
EXW37_03955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW37_03960	COG0351	phosphomethylpyrimidine kinase
EXW37_03985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW37_03990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW37_03995	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW37_04000	COG2205	protein histidine kinase activity
EXW37_04005	COG2814	Major facilitator Superfamily
EXW37_04010	COG1846	Transcriptional regulator
EXW37_04030	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW37_04035	COG1129	ABC transporter
EXW37_04040	COG1879	ABC-type sugar transport system periplasmic component
EXW37_04045	COG2252	PERMEase
EXW37_04050	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_04115	COG0778	Nitroreductase
EXW37_04120	COG2719	SpoVR family
EXW37_04145	COG1937	Protein conserved in bacteria
EXW37_04150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW37_04150	COG0425	Belongs to the sulfur carrier protein TusA family
EXW37_04155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW37_04155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW37_04160	COG0425	Belongs to the sulfur carrier protein TusA family
EXW37_04165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW37_04165	COG0425	Belongs to the sulfur carrier protein TusA family
EXW37_04170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW37_04175	COG2210	Belongs to the sulfur carrier protein TusA family
EXW37_04180	COG0730	response to heat
EXW37_04190	COG1316	TRANSCRIPTIONal
EXW37_04210	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW37_04215	COG0604	alcohol dehydrogenase
EXW37_04220	COG2814	Major facilitator Superfamily
EXW37_04235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW37_04235	COG3711	transcriptional antiterminator
EXW37_04240	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW37_04245	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW37_04270	COG3584	3D domain protein
EXW37_04270	COG1388	LysM domain
EXW37_04275	COG0577	efflux transmembrane transporter activity
EXW37_04280	COG1136	(ABC) transporter
EXW37_04290	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW37_04305	COG1114	Component of the transport system for branched-chain amino acids
EXW37_04310	COG3546	catalase activity
EXW37_04340	COG0586	Pfam SNARE associated Golgi protein
EXW37_04370	COG0531	amino acid
EXW37_04375	COG0475	glutathione-regulated potassium exporter activity
EXW37_04385	COG1737	Transcriptional regulator
EXW37_04395	COG1263	PTS System
EXW37_04395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW37_04405	COG2259	Doxx family
EXW37_04430	COG1522	sequence-specific DNA binding
EXW37_04455	COG2076	Multidrug Resistance protein
EXW37_04460	COG1309	transcriptional regulator
EXW37_04465	COG2814	Major facilitator Superfamily
EXW37_04470	COG1733	regulation of RNA biosynthetic process
EXW37_04485	COG4533	DNA binding
EXW37_04490	COG2211	Major facilitator Superfamily
EXW37_04510	COG0531	amino acid
EXW37_04515	COG1012	belongs to the aldehyde dehydrogenase family
EXW37_04530	COG1132	(ABC) transporter
EXW37_04535	COG1132	(ABC) transporter
EXW37_04540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW37_04545	COG0765	amino acid transport
EXW37_04550	COG1126	abc transporter atp-binding protein
EXW37_04565	COG0189	ligase activity
EXW37_04575	COG4399	Belongs to the UPF0754 family
EXW37_04580	COG3679	Belongs to the UPF0342 family
EXW37_04595	COG0028	Belongs to the TPP enzyme family
EXW37_04600	COG3527	Alpha-acetolactate decarboxylase
EXW37_04605	COG0463	Glycosyl transferase, family 2
EXW37_04610	COG1216	Glycosyl transferase, family 2
EXW37_04615	COG2094	Belongs to the DNA glycosylase MPG family
EXW37_04620	COG0561	phosphatase activity
EXW37_04630	COG3409	Peptidoglycan-binding domain 1 protein
EXW37_04630	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW37_04635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW37_04640	COG0318	PFAM AMP-dependent synthetase and ligase
EXW37_04650	COG0659	secondary active sulfate transmembrane transporter activity
EXW37_04655	COG2244	polysaccharide biosynthetic process
EXW37_04675	COG1024	Enoyl-CoA hydratase
EXW37_04705	COG1363	Peptidase, m42
EXW37_04720	COG2318	DinB family
EXW37_04740	COG0579	oxidoreductase
EXW37_04765	COG0601	transmembrane transport
EXW37_04770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW37_04775	COG0444	Belongs to the ABC transporter superfamily
EXW37_04780	COG4608	Belongs to the ABC transporter superfamily
EXW37_04805	COG0477	Major facilitator Superfamily
EXW37_04810	COG3290	protein histidine kinase activity
EXW37_04815	COG4565	transcriptional regulatory protein
EXW37_04880	COG0305	Participates in initiation and elongation during chromosome replication
EXW37_04910	COG1842	Phage shock protein A
EXW37_04920	COG0477	Major facilitator Superfamily
EXW37_04970	COG2814	Major facilitator Superfamily
EXW37_04975	COG0640	Transcriptional regulator
EXW37_05000	COG2376	Dihydroxyacetone kinase
EXW37_05020	COG2376	Dihydroxyacetone kinase
EXW37_05035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW37_05050	COG0457	Tetratricopeptide repeat
EXW37_05060	COG2373	Large extracellular alpha-helical protein
EXW37_05080	COG2211	Major facilitator Superfamily
EXW37_05120	COG0825	malonyl-CoA metabolic process
EXW37_05145	COG2807	transmembrane transport
EXW37_05165	COG4585	Histidine kinase
EXW37_05170	COG2197	response regulator
EXW37_05200	COG0420	3'-5' exonuclease activity
EXW37_05205	COG4717	serine-type aminopeptidase activity
EXW37_05215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW37_05220	COG0346	lactoylglutathione lyase activity
EXW37_05225	COG0346	lactoylglutathione lyase activity
EXW37_05230	COG0457	Tetratricopeptide repeat
EXW37_05245	COG2267	carboxylic ester hydrolase activity
EXW37_05255	COG3620	sequence-specific DNA binding
EXW37_05260	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW37_05265	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW37_05270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW37_05275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW37_05280	COG1695	Transcriptional regulator
EXW37_05300	COG1595	DNA-templated transcription, initiation
EXW37_05315	COG3973	AAA domain
EXW37_05320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW37_05345	COG0537	adenosine 5'-monophosphoramidase activity
EXW37_05350	COG1131	(ABC) transporter
EXW37_05355	COG4473	ABC transporter
EXW37_05365	COG0247	lactate metabolic process
EXW37_05370	COG1139	Iron-sulfur cluster binding protein
EXW37_05375	COG1556	Lactate utilization protein
EXW37_05395	COG3402	PFAM membrane-flanked domain
EXW37_05400	COG3428	Bacterial PH domain
EXW37_05440	COG3402	PFAM membrane-flanked domain
EXW37_05445	COG3428	Bacterial PH domain
EXW37_05450	COG2329	Antibiotic biosynthesis monooxygenase
EXW37_05455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW37_05460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW37_05465	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW37_05470	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW37_05490	COG1309	transcriptional regulator
EXW37_05495	COG1511	domain protein
EXW37_05530	COG1609	Transcriptional regulator
EXW37_05540	COG1234	tRNA 3'-trailer cleavage
EXW37_05545	COG0095	Lipoate-protein ligase
EXW37_05555	COG0318	PFAM AMP-dependent synthetase and ligase
EXW37_05570	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW37_05580	COG4208	sulfate ABC transporter
EXW37_05590	COG3209	COG3209 Rhs family protein
EXW37_05655	COG1408	metallophosphoesterase
EXW37_05660	COG1078	dGTPase activity
EXW37_05675	COG1595	DNA-templated transcription, initiation
EXW37_05685	COG3708	Transcriptional regulator
EXW37_05685	COG2207	Transcriptional regulator
EXW37_05690	COG2205	protein histidine kinase activity
EXW37_05695	COG0745	RESPONSE REGULATOR receiver
EXW37_05715	COG0501	Belongs to the peptidase M48B family
EXW37_05720	COG0840	transmembrane signaling receptor activity
EXW37_05725	COG0697	spore germination
EXW37_05730	COG3693	PFAM glycoside hydrolase, family 10
EXW37_05735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW37_05740	COG2224	Isocitrate lyase
EXW37_05750	COG1278	Cold shock
EXW37_05770	COG4903	ComK protein
EXW37_05775	COG0398	Pfam SNARE associated Golgi protein
EXW37_05785	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW37_05790	COG1074	ATP-dependent DNA helicase activity
EXW37_05840	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW37_05865	COG0367	asparagine synthase
EXW37_05885	COG0753	catalase activity
EXW37_05890	COG0004	ammonium transporteR
EXW37_05900	COG1666	GTP binding
EXW37_05905	COG2996	Protein conserved in bacteria
EXW37_05920	COG1329	Transcriptional regulator
EXW37_05955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW37_05965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW37_05980	COG0561	phosphatase activity
EXW37_06000	COG2267	carboxylic ester hydrolase activity
EXW37_06015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW37_06020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW37_06025	COG5504	Zn-dependent protease
EXW37_06045	COG0180	Tryptophanyl-tRNA synthetase
EXW37_06060	COG4166	transmembrane transport
EXW37_06065	COG0601	transmembrane transport
EXW37_06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW37_06075	COG0444	Belongs to the ABC transporter superfamily
EXW37_06080	COG4608	Belongs to the ABC transporter superfamily
EXW37_06085	COG0534	Mate efflux family protein
EXW37_06090	COG4166	transmembrane transport
EXW37_06110	COG0861	Integral membrane protein TerC family
EXW37_06115	COG4862	establishment of competence for transformation
EXW37_06120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW37_06130	COG1164	Oligoendopeptidase f
EXW37_06140	COG2346	COG2346, Truncated hemoglobins
EXW37_06145	COG4116	CYTH
EXW37_06155	COG2357	RelA SpoT domain protein
EXW37_06165	COG0564	pseudouridine synthase activity
EXW37_06175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW37_06180	COG0772	Belongs to the SEDS family
EXW37_06185	COG1216	Glycosyl transferase, family 2
EXW37_06205	COG0463	Glycosyl transferase, family 2
EXW37_06205	COG0457	Tetratricopeptide repeat
EXW37_06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW37_06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW37_06285	COG2153	protein acetylation
EXW37_06290	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW37_06295	COG2382	esterase
EXW37_06320	COG5492	domain, Protein
EXW37_06325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW37_06340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW37_06340	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW37_06345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW37_06350	COG0134	indole-3-glycerol-phosphate synthase activity
EXW37_06355	COG0135	phosphoribosylanthranilate isomerase activity
EXW37_06360	COG0133	tryptophan synthase activity
EXW37_06365	COG0159	tryptophan synthase activity
EXW37_06375	COG1620	l-lactate permease
EXW37_06380	COG5634	Uncharacterized conserved protein (DUF2278)
EXW37_06440	COG2226	methyltransferase
EXW37_06460	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW37_06465	COG0567	Dehydrogenase, E1 component
EXW37_06470	COG1476	TRANSCRIPTIONal
EXW37_06495	COG4152	abc transporter atp-binding protein
EXW37_06500	COG1668	transmembrane transport
EXW37_06525	COG1686	Belongs to the peptidase S11 family
EXW37_06530	COG0681	Belongs to the peptidase S26 family
EXW37_06565	COG1012	belongs to the aldehyde dehydrogenase family
EXW37_06575	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW37_06580	COG1177	transmembrane transport
EXW37_06585	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW37_06595	COG2409	Drug exporters of the RND superfamily
EXW37_06605	COG0564	pseudouridine synthase activity
EXW37_06615	COG2340	Cysteine-rich secretory protein family
EXW37_06620	COG0247	lactate metabolic process
EXW37_06625	COG0277	FAD linked oxidase domain protein
EXW37_06630	COG3835	regulator
EXW37_06640	COG0745	RESPONSE REGULATOR receiver
EXW37_06645	COG5002	protein histidine kinase activity
EXW37_06650	COG2186	Transcriptional regulator
EXW37_06655	COG0247	lactate metabolic process
EXW37_06660	COG1139	Iron-sulfur cluster binding protein
EXW37_06665	COG1556	Lactate utilization protein
EXW37_06670	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW37_06680	COG2116	formate transmembrane transporter activity
EXW37_06685	COG0861	Integral membrane protein TerC family
EXW37_06690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW37_06700	COG2030	dehydratase
EXW37_06720	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_06725	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW37_06735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW37_06750	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW37_06755	COG3842	ATPase activity
EXW37_06770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW37_06780	COG1349	DNA-binding transcription factor activity
EXW37_06790	COG0235	Class ii aldolase
EXW37_06800	COG2861	carbohydrate metabolic process
EXW37_06810	COG3852	Histidine kinase
EXW37_06815	COG1846	Transcriptional regulator
EXW37_06825	COG2318	DinB family
EXW37_06830	COG5002	protein histidine kinase activity
EXW37_06835	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW37_06840	COG0720	synthase
EXW37_06850	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW37_06855	COG4873	Protein conserved in bacteria
EXW37_06865	COG0456	acetyltransferase
EXW37_06885	COG1780	Probably involved in ribonucleotide reductase function
EXW37_06900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW37_06905	COG0531	amino acid
EXW37_06910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW37_06925	COG2204	response regulator
EXW37_06930	COG1012	belongs to the aldehyde dehydrogenase family
EXW37_06940	COG1725	Transcriptional regulator
EXW37_06945	COG1131	(ABC) transporter
EXW37_06955	COG1131	(ABC) transporter
EXW37_06960	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW37_06965	COG1266	CAAX protease self-immunity
EXW37_06975	COG1522	sequence-specific DNA binding
EXW37_06985	COG1335	isochorismatase
EXW37_06995	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW37_07000	COG2070	2-Nitropropane dioxygenase
EXW37_07005	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW37_07010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW37_07015	COG1696	Membrane protein involved in D-alanine export
EXW37_07020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW37_07035	COG0716	FMN binding
EXW37_07060	COG0534	Mate efflux family protein
EXW37_07085	COG1846	Transcriptional regulator
EXW37_07095	COG1301	dicarboxylic acid transport
EXW37_07100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW37_07110	COG3874	Sporulation protein YtfJ
EXW37_07130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW37_07135	COG0028	Belongs to the TPP enzyme family
EXW37_07140	COG0440	acetolactate synthase activity
EXW37_07150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW37_07160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW37_07170	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW37_07175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW37_07185	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW37_07190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW37_07195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW37_07200	COG0107	imidazoleglycerol-phosphate synthase activity
EXW37_07210	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW37_07215	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW37_07230	COG1183	phosphatidylcholine synthase activity
EXW37_07235	COG1368	sulfuric ester hydrolase activity
EXW37_07245	COG0019	diaminopimelate decarboxylase activity
EXW37_07255	COG0175	sulfate reduction
EXW37_07260	COG2046	Belongs to the sulfate adenylyltransferase family
EXW37_07265	COG0529	Catalyzes the synthesis of activated sulfate
EXW37_07270	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW37_07290	COG1648	precorrin-2 dehydrogenase activity
EXW37_07295	COG0733	neurotransmitter:sodium symporter activity
EXW37_07315	COG1757	Na H antiporter
EXW37_07335	COG4758	membrane
EXW37_07340	COG4585	Histidine kinase
EXW37_07345	COG2197	response regulator
EXW37_07355	COG1114	Component of the transport system for branched-chain amino acids
EXW37_07365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW37_07410	COG0730	response to heat
EXW37_07415	COG0306	phosphate transporter
EXW37_07420	COG1392	Phosphate transport regulator
EXW37_07425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW37_07440	COG3852	Histidine kinase
EXW37_07445	COG1801	Protein of unknown function DUF72
EXW37_07455	COG0582	viral genome integration into host DNA
EXW37_07460	COG5002	protein histidine kinase activity
EXW37_07475	COG0392	lysyltransferase activity
EXW37_07475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW37_07490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW37_07495	COG1686	Belongs to the peptidase S11 family
EXW37_07500	COG2715	membrane protein required for spore maturation
EXW37_07505	COG0700	Nucleoside recognition
EXW37_07510	COG1187	pseudouridine synthase activity
EXW37_07520	COG1333	cytochrome c biogenesis protein
EXW37_07525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW37_07530	COG0745	RESPONSE REGULATOR receiver
EXW37_07535	COG5002	protein histidine kinase activity
EXW37_07540	COG2096	Adenosyltransferase
EXW37_07545	COG4942	peptidase
EXW37_07555	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW37_07560	COG1141	Ferredoxin
EXW37_07570	COG4955	Helix-turn-helix domain
EXW37_07575	COG0514	ATP-dependent DNA helicase (RecQ)
EXW37_07580	COG1266	CAAX protease self-immunity
EXW37_07590	COG1408	metallophosphoesterase
EXW37_07605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW37_07625	COG0492	ferredoxin-NADP+ reductase activity
EXW37_07630	COG0252	asparaginase activity
EXW37_07635	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW37_07645	COG1304	FMN binding
EXW37_07675	COG1160	GTP binding
EXW37_07680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW37_07700	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW37_07750	COG0302	gtp cyclohydrolase
EXW37_07755	COG0142	geranyltranstransferase activity
EXW37_07760	COG2226	methyltransferase
EXW37_07765	COG0142	geranyltranstransferase activity
EXW37_07780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW37_07790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW37_07795	COG0457	Tetratricopeptide repeat
EXW37_07800	COG5582	Belongs to the UPF0302 family
EXW37_07815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW37_07830	COG4347	Protein of unknown function (DUF1405)
EXW37_07845	COG2738	Putative neutral zinc metallopeptidase
EXW37_07855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW37_07860	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW37_07865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW37_07870	COG1803	Methylglyoxal synthase
EXW37_07875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW37_07880	COG0438	transferase activity, transferring glycosyl groups
EXW37_07885	COG0617	tRNA 3'-terminal CCA addition
EXW37_07895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW37_07900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW37_07910	COG1199	ATP-dependent helicase activity
EXW37_07910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW37_07930	COG3935	DnaD domain protein
EXW37_07935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW37_07945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW37_07945	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW37_07950	COG3331	DNA recombination
EXW37_07985	COG4474	Belongs to the UPF0398 family
EXW37_07990	COG3599	regulation of cell shape
EXW37_08000	COG0116	Belongs to the methyltransferase superfamily
EXW37_08010	COG1199	ATP-dependent helicase activity
EXW37_08015	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW37_08025	COG0024	Methionine aminopeptidase
EXW37_08035	COG2233	PERMEase
EXW37_08040	COG2311	Membrane
EXW37_08050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW37_08060	COG0456	acetyltransferase
EXW37_08110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW37_08125	COG0454	-acetyltransferase
EXW37_08145	COG0328	RNA-DNA hybrid ribonuclease activity
EXW37_08180	COG3403	YqcI/YcgG family
EXW37_08185	COG1280	lysine exporter protein (LysE YggA)
EXW37_08200	COG3162	membrane
EXW37_08205	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW37_08210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW37_08220	COG0475	glutathione-regulated potassium exporter activity
EXW37_08225	COG0789	Transcriptional regulator
EXW37_08225	COG4978	Transcriptional regulator
EXW37_08230	COG0534	Mate efflux family protein
EXW37_08235	COG2323	membrane
EXW37_08240	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW37_08265	COG2814	Major facilitator Superfamily
EXW37_08285	COG1923	regulation of RNA biosynthetic process
EXW37_08295	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW37_08300	COG1360	Flagellar Motor Protein
EXW37_08305	COG2201	protein-glutamate methylesterase activity
EXW37_08310	COG0643	Histidine kinase
EXW37_08310	COG2198	Histidine kinase
EXW37_08315	COG1776	CheC inhibitor of MCP methylation
EXW37_08315	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW37_08330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW37_08350	COG1256	bacterial-type flagellum assembly
EXW37_08355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW37_08375	COG1815	bacterial-type flagellum-dependent cell motility
EXW37_08380	COG1558	bacterial-type flagellum-dependent cell motility
EXW37_08390	COG1766	The M ring may be actively involved in energy transduction
EXW37_08395	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW37_08405	COG1157	protein secretion by the type III secretion system
EXW37_08425	COG1749	Flagellar hook protein flgE
EXW37_08440	COG0784	Response regulator, receiver
EXW37_08440	COG0835	chemotaxis
EXW37_08465	COG0861	Integral membrane protein TerC family
EXW37_08475	COG3383	formate dehydrogenase (NAD+) activity
EXW37_08480	COG2427	Protein of unknown function (DUF1641)
EXW37_08485	COG5609	conserved protein (DUF2294)
EXW37_08490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW37_08500	COG2116	formate transmembrane transporter activity
EXW37_08505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW37_08510	COG0303	'Molybdopterin
EXW37_08515	COG0314	molybdopterin synthase activity
EXW37_08520	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW37_08530	COG0489	protein tyrosine kinase activity
EXW37_08535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW37_08540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW37_08545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW37_08550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW37_08555	COG0741	lytic transglycosylase activity
EXW37_08565	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW37_08570	COG1776	CheC inhibitor of MCP methylation
EXW37_08570	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW37_08580	COG1338	Plays a role in the flagellum-specific transport system
EXW37_08585	COG1987	bacterial-type flagellum assembly
EXW37_08595	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW37_08600	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW37_08605	COG1419	protein localization to endoplasmic reticulum
EXW37_08610	COG4786	Flagellar basal body rod
EXW37_08625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW37_08660	COG2329	Antibiotic biosynthesis monooxygenase
EXW37_08675	COG2814	Major facilitator Superfamily
EXW37_08685	COG0583	DNA-binding transcription factor activity
EXW37_08690	COG3842	ATPase activity
EXW37_08740	COG0406	alpha-ribazole phosphatase activity
EXW37_08770	COG0367	asparagine synthase
EXW37_08800	COG1802	Transcriptional regulator
EXW37_08805	COG0697	spore germination
EXW37_08825	COG1216	Glycosyl transferase, family 2
EXW37_08825	COG0438	transferase activity, transferring glycosyl groups
EXW37_08830	COG1757	Na H antiporter
EXW37_08855	COG0534	Mate efflux family protein
EXW37_08860	COG3340	Belongs to the peptidase S51 family
EXW37_08880	COG0785	Cytochrome C biogenesis protein
EXW37_08885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW37_08900	COG3048	D-serine ammonia-lyase activity
EXW37_08905	COG2733	membrane
EXW37_08945	COG1131	(ABC) transporter
EXW37_08965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW37_08970	COG0528	UMP kinase activity
EXW37_08980	COG1027	Aspartate ammonia-lyase
EXW37_08985	COG0281	malic enzyme
EXW37_08990	COG4191	Histidine kinase
EXW37_08995	COG0784	Response regulator, receiver
EXW37_09000	COG1846	Transcriptional regulator
EXW37_09010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW37_09025	COG2502	aspartate--ammonia ligase
EXW37_09030	COG3620	sequence-specific DNA binding
EXW37_09095	COG1695	Transcriptional regulator
EXW37_09110	COG0477	Major facilitator Superfamily
EXW37_09120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW37_09130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW37_09135	COG2223	nitrite transmembrane transporter activity
EXW37_09140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW37_09155	COG2244	polysaccharide biosynthetic process
EXW37_09160	COG0733	neurotransmitter:sodium symporter activity
EXW37_09170	COG5566	PFAM Mor transcription activator
EXW37_09175	COG2323	membrane
EXW37_09195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW37_09200	COG2132	Multicopper oxidase
EXW37_09210	COG5002	protein histidine kinase activity
EXW37_09215	COG0745	RESPONSE REGULATOR receiver
EXW37_09225	COG0129	dihydroxy-acid dehydratase activity
EXW37_09230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW37_09255	COG2814	Major facilitator Superfamily
EXW37_09260	COG3384	dioxygenase
EXW37_09295	COG1073	alpha beta
EXW37_09300	COG4166	transmembrane transport
EXW37_09305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW37_09325	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW37_09330	COG1054	Belongs to the UPF0176 family
EXW37_09340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW37_09345	COG0531	amino acid
EXW37_09380	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW37_09395	COG4257	antibiotic catabolic process
EXW37_09400	COG2390	Transcriptional regulator
EXW37_09410	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW37_09415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW37_09420	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW37_09435	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW37_09450	COG0583	DNA-binding transcription factor activity
EXW37_09465	COG0006	proline dipeptidase activity
EXW37_09470	COG2132	Multicopper oxidase
EXW37_09485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW37_09505	COG1114	Component of the transport system for branched-chain amino acids
EXW37_09515	COG1276	copper resistance
EXW37_09515	COG2372	response to copper ion
EXW37_09520	COG4549	nuclear export factor GLE1
EXW37_09530	COG0697	spore germination
EXW37_09535	COG0583	DNA-binding transcription factor activity
EXW37_09540	COG1959	2 iron, 2 sulfur cluster binding
EXW37_09545	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW37_09550	COG0778	Nitroreductase
EXW37_09560	COG0628	permease
EXW37_09575	COG1231	oxidoreductase activity
EXW37_09580	COG0523	cobalamin synthesis protein
EXW37_09590	COG0411	ABC transporter
EXW37_09610	COG0583	DNA-binding transcription factor activity
EXW37_09620	COG1942	4-Oxalocrotonate Tautomerase
EXW37_09635	COG0346	lactoylglutathione lyase activity
EXW37_09645	COG1271	oxidase subunit
EXW37_09650	COG1294	oxidase, subunit
EXW37_09655	COG4988	ABC transporter
EXW37_09660	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW37_09685	COG1686	Belongs to the peptidase S11 family
EXW37_09700	COG0791	NLP P60 protein
EXW37_09700	COG1388	LysM domain
EXW37_09710	COG1132	(ABC) transporter
EXW37_09715	COG0745	RESPONSE REGULATOR receiver
EXW37_09720	COG5002	protein histidine kinase activity
EXW37_09725	COG0300	oxidoreductase activity
EXW37_09730	COG4122	O-methyltransferase activity
EXW37_09750	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EXW37_09760	COG0460	homoserine dehydrogenase
EXW37_09770	COG0083	homoserine kinase activity
EXW37_09785	COG1316	TRANSCRIPTIONal
EXW37_09800	COG1285	pathogenesis
EXW37_09805	COG1247	-acetyltransferase
EXW37_09825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW37_09835	COG1082	Xylose isomerase domain protein TIM barrel
EXW37_09845	COG2814	Major facilitator Superfamily
EXW37_09850	COG1279	arginine transmembrane transporter activity
EXW37_09855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW37_09865	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW37_09895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW37_09900	COG0577	efflux transmembrane transporter activity
EXW37_09905	COG2002	toxin-antitoxin pair type II binding
EXW37_09910	COG1404	Belongs to the peptidase S8 family
EXW37_09915	COG0640	Transcriptional regulator
EXW37_09920	COG0667	Aldo Keto reductase
EXW37_09965	COG3949	Membrane
EXW37_09970	COG0783	Belongs to the Dps family
EXW37_09985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW37_09995	COG1231	oxidoreductase activity
EXW37_10000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW37_10005	COG4989	oxidoreductase activity
EXW37_10010	COG0523	cobalamin synthesis protein
EXW37_10015	COG0456	acetyltransferase
EXW37_10020	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW37_10045	COG1136	(ABC) transporter
EXW37_10050	COG0577	efflux transmembrane transporter activity
EXW37_10055	COG0745	RESPONSE REGULATOR receiver
EXW37_10060	COG2205	protein histidine kinase activity
EXW37_10065	COG1902	pentaerythritol trinitrate reductase activity
EXW37_10070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW37_10080	COG4166	transmembrane transport
EXW37_10085	COG0346	lactoylglutathione lyase activity
EXW37_10095	COG0406	alpha-ribazole phosphatase activity
EXW37_10105	COG5337	Spore coat protein CotH
EXW37_10110	COG1051	belongs to the nudix hydrolase family
EXW37_10115	COG0586	Pfam SNARE associated Golgi protein
EXW37_10120	COG2244	polysaccharide biosynthetic process
EXW37_10130	COG0701	Predicted permease
EXW37_10135	COG3689	TIGRFAM TIGR03943 family protein
EXW37_10140	COG1607	acyl-coa hydrolase
EXW37_10150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW37_10165	COG0702	epimerase
EXW37_10170	COG2839	Protein conserved in bacteria
EXW37_10175	COG1253	flavin adenine dinucleotide binding
EXW37_10200	COG1114	Component of the transport system for branched-chain amino acids
EXW37_10205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW37_10225	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW37_10240	COG1876	peptidase activity
EXW37_10245	COG0494	nUDIX hydrolase
EXW37_10255	COG2211	Major facilitator Superfamily
EXW37_10270	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW37_10280	COG0561	phosphatase activity
EXW37_10285	COG1846	Transcriptional regulator
EXW37_10290	COG2814	Major facilitator Superfamily
EXW37_10300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW37_10305	COG4106	trans-aconitate 2-methyltransferase activity
EXW37_10320	COG1819	glycosyl
EXW37_10325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW37_10330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW37_10355	COG0456	acetyltransferase
EXW37_10375	COG3874	Sporulation protein YtfJ
EXW37_10400	COG2226	methyltransferase
EXW37_10430	COG0604	alcohol dehydrogenase
EXW37_10435	COG1595	DNA-templated transcription, initiation
EXW37_10460	COG0426	domain, Protein
EXW37_10460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW37_10470	COG0386	Belongs to the glutathione peroxidase family
EXW37_10475	COG1305	Transglutaminase-like
EXW37_10480	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW37_10485	COG0714	Associated with various cellular activities
EXW37_10490	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW37_10495	COG1140	nitrate reductase beta subunit
EXW37_10500	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW37_10505	COG2181	nitrate reductase activity
EXW37_10510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW37_10515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW37_10520	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW37_10525	COG0303	'Molybdopterin
EXW37_10530	COG0314	molybdopterin synthase activity
EXW37_10540	COG2223	nitrite transmembrane transporter activity
EXW37_10560	COG1648	precorrin-2 dehydrogenase activity
EXW37_10570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW37_10570	COG1587	Uroporphyrinogen-III synthase
EXW37_10575	COG2146	nitrite reductase [NAD(P)H] activity
EXW37_10580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW37_10585	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW37_10615	COG2359	stage V sporulation protein S
EXW37_10625	COG2856	Zn peptidase
EXW37_10640	COG0494	nUDIX hydrolase
EXW37_10645	COG0326	Molecular chaperone. Has ATPase activity
EXW37_10650	COG1396	sequence-specific DNA binding
EXW37_10755	COG0582	viral genome integration into host DNA
EXW37_10770	COG5484	DNA packaging
EXW37_10775	COG1783	phage Terminase large subunit
EXW37_10790	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EXW37_10910	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW37_10920	COG1418	mRNA catabolic process
EXW37_10925	COG0488	(ABC) transporter
EXW37_10945	COG1413	lyase activity
EXW37_10960	COG2521	methyltransferase
EXW37_10960	COG2136	Putative SAM-dependent methyltransferase
EXW37_10965	COG0018	arginyl-trna synthetase
EXW37_11020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW37_11030	COG0017	Asparaginyl-tRNA synthetase
EXW37_11035	COG0733	neurotransmitter:sodium symporter activity
EXW37_11065	COG2610	gluconate transmembrane transporter activity
EXW37_11075	COG1794	racemase activity, acting on amino acids and derivatives
EXW37_11085	COG0456	acetyltransferase
EXW37_11090	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW37_11095	COG1131	(ABC) transporter
EXW37_11100	COG4473	ABC transporter
EXW37_11110	COG0546	phosphoglycolate phosphatase activity
EXW37_11165	COG0768	penicillin binding
EXW37_11175	COG0204	Acyl-transferase
EXW37_11180	COG1272	protein, Hemolysin III
EXW37_11185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW37_11190	COG0805	protein transport
EXW37_11205	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW37_11210	COG1999	signal sequence binding
EXW37_11215	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW37_11220	COG0367	asparagine synthase
EXW37_11235	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW37_11245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW37_11265	COG1335	isochorismatase
EXW37_11275	COG0668	transmembrane transport
EXW37_11280	COG4585	Histidine kinase
EXW37_11280	COG2203	Gaf domain
EXW37_11285	COG2197	response regulator
EXW37_11290	COG1737	Transcriptional regulator
EXW37_11295	COG1064	alcohol dehydrogenase
EXW37_11310	COG1070	Carbohydrate kinase
EXW37_11320	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW37_11340	COG1125	glycine betaine transport
EXW37_11340	COG0517	IMP dehydrogenase activity
EXW37_11345	COG1174	glycine betaine transport
EXW37_11380	COG1253	flavin adenine dinucleotide binding
EXW37_11385	COG1012	belongs to the aldehyde dehydrogenase family
EXW37_11390	COG5506	Protein of unknown function (DUF1694)
EXW37_11405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW37_11410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW37_11415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW37_11420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW37_11425	COG0456	acetyltransferase
EXW37_11430	COG3829	transcription factor binding
EXW37_11435	COG1509	lysine 2,3-aminomutase activity
EXW37_11445	COG4479	Belongs to the UPF0346 family
EXW37_11470	COG3064	Membrane
EXW37_11470	COG0515	serine threonine protein kinase
EXW37_11470	COG4991	sh3 domain protein
EXW37_11480	COG0671	phosphoesterase, PA-phosphatase related
EXW37_11485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW37_11490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW37_11550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW37_11575	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_11595	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW37_11595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW37_11605	COG2814	Major facilitator Superfamily
EXW37_11615	COG0372	Belongs to the citrate synthase family
EXW37_11620	COG2079	MmgE PrpD family protein
EXW37_11625	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW37_11630	COG1960	acyl-CoA dehydrogenase activity
EXW37_11635	COG2084	Dehydrogenase
EXW37_11640	COG1012	belongs to the aldehyde dehydrogenase family
EXW37_11645	COG1280	lysine exporter protein (LysE YggA)
EXW37_11650	COG1024	Enoyl-CoA hydratase
EXW37_11665	COG0420	3'-5' exonuclease activity
EXW37_11685	COG2223	nitrite transmembrane transporter activity
EXW37_11690	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_11695	COG1169	isochorismate synthase
EXW37_11700	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW37_11705	COG3433	isochorismatase activity
EXW37_11705	COG1535	isochorismatase
EXW37_11710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW37_11715	COG3251	PFAM MbtH domain protein
EXW37_11720	COG2814	Major facilitator Superfamily
EXW37_11735	COG0776	regulation of translation
EXW37_11745	COG2318	DinB family
EXW37_11750	COG1115	amino acid carrier protein
EXW37_11765	COG2329	Antibiotic biosynthesis monooxygenase
EXW37_11780	COG1187	pseudouridine synthase activity
EXW37_11785	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW37_11790	COG3655	Transcriptional regulator
EXW37_11800	COG1136	(ABC) transporter
EXW37_11810	COG0596	Alpha beta hydrolase
EXW37_11830	COG0028	Belongs to the TPP enzyme family
EXW37_11855	COG1253	flavin adenine dinucleotide binding
EXW37_11905	COG1846	Transcriptional regulator
EXW37_11920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW37_11925	COG1309	transcriptional regulator
EXW37_11935	COG0697	spore germination
EXW37_11940	COG0531	amino acid
EXW37_11955	COG1247	-acetyltransferase
EXW37_11995	COG0596	Alpha beta hydrolase
EXW37_12000	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW37_12010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW37_12040	COG0583	DNA-binding transcription factor activity
EXW37_12045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW37_12060	COG0583	DNA-binding transcription factor activity
EXW37_12065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW37_12070	COG2258	MOSC domain
EXW37_12080	COG1132	(ABC) transporter
EXW37_12085	COG1132	(ABC) transporter
EXW37_12105	COG1396	sequence-specific DNA binding
EXW37_12140	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW37_12145	COG1595	DNA-templated transcription, initiation
EXW37_12165	COG1649	PFAM Uncharacterised BCR, COG1649
EXW37_12185	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW37_12190	COG2971	BadF BadG BcrA BcrD
EXW37_12260	COG3615	Tellurite resistance protein tehB
EXW37_12260	COG0500	methyltransferase
EXW37_12270	COG0693	protein deglycase activity
EXW37_12280	COG0588	phosphoglycerate mutase activity
EXW37_12300	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW37_12305	COG0110	maltose O-acetyltransferase activity
EXW37_12320	COG1136	(ABC) transporter
EXW37_12335	COG5002	protein histidine kinase activity
EXW37_12340	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_12350	COG1686	Belongs to the peptidase S11 family
EXW37_12375	COG0768	penicillin binding
EXW37_12380	COG0745	RESPONSE REGULATOR receiver
EXW37_12385	COG2205	protein histidine kinase activity
EXW37_12390	COG1136	(ABC) transporter
EXW37_12395	COG0577	efflux transmembrane transporter activity
EXW37_12405	COG1595	DNA-templated transcription, initiation
EXW37_12415	COG0768	penicillin binding
EXW37_12420	COG0768	penicillin binding
EXW37_12455	COG1252	NADH dehydrogenase
EXW37_12460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW37_12460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW37_12475	COG0697	spore germination
EXW37_12505	COG3397	chitin binding
EXW37_12510	COG0823	Involved in the tonB-independent uptake of proteins
EXW37_12520	COG1408	metallophosphoesterase
EXW37_12530	COG1131	(ABC) transporter
EXW37_12540	COG1309	transcriptional regulator
EXW37_12550	COG1960	acyl-CoA dehydrogenase activity
EXW37_12555	COG0439	Biotin carboxylase
EXW37_12560	COG0511	ligase activity, forming carbon-carbon bonds
EXW37_12565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW37_12570	COG1024	Enoyl-CoA hydratase
EXW37_12575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW37_12580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW37_12630	COG0572	uridine kinase
EXW37_12635	COG2318	DinB family
EXW37_12665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW37_12695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW37_12720	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_12725	COG1733	regulation of RNA biosynthetic process
EXW37_12750	COG1309	transcriptional regulator
EXW37_12765	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW37_12780	COG0697	spore germination
EXW37_12785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW37_12815	COG2323	membrane
EXW37_12830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW37_12835	COG0697	spore germination
EXW37_12855	COG0201	protein transport
EXW37_12865	COG0737	Belongs to the 5'-nucleotidase family
EXW37_12875	COG3227	Zinc metalloprotease (Elastase)
EXW37_12880	COG1523	belongs to the glycosyl hydrolase 13 family
EXW37_12895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW37_12900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW37_12905	COG1073	alpha beta
EXW37_12915	COG0577	efflux transmembrane transporter activity
EXW37_12920	COG1136	(ABC) transporter
EXW37_12950	COG5002	protein histidine kinase activity
EXW37_12955	COG0745	RESPONSE REGULATOR receiver
EXW37_12960	COG1011	Hydrolase
EXW37_12985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW37_12990	COG1183	phosphatidylcholine synthase activity
EXW37_13005	COG1132	(ABC) transporter
EXW37_13015	COG3961	Belongs to the TPP enzyme family
EXW37_13035	COG0322	excinuclease ABC activity
EXW37_13060	COG2318	DinB family
EXW37_13075	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW37_13100	COG3878	Protein conserved in bacteria
EXW37_13125	COG1051	belongs to the nudix hydrolase family
EXW37_13130	COG0592	DNA-directed DNA polymerase activity
EXW37_13135	COG2816	NAD+ diphosphatase activity
EXW37_13145	COG2223	nitrite transmembrane transporter activity
EXW37_13150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW37_13160	COG0494	nUDIX hydrolase
EXW37_13180	COG0697	spore germination
EXW37_13185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW37_13200	COG0584	glycerophosphoryl diester phosphodiesterase
EXW37_13215	COG1733	regulation of RNA biosynthetic process
EXW37_13225	COG2814	Major facilitator Superfamily
EXW37_13240	COG1132	(ABC) transporter
EXW37_13240	COG2375	cellular response to nickel ion
EXW37_13245	COG1132	(ABC) transporter
EXW37_13280	COG0768	penicillin binding
EXW37_13285	COG0671	phosphoesterase, PA-phosphatase related
EXW37_13290	COG0604	alcohol dehydrogenase
EXW37_13295	COG5002	protein histidine kinase activity
EXW37_13300	COG0745	RESPONSE REGULATOR receiver
EXW37_13310	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW37_13320	COG2205	protein histidine kinase activity
EXW37_13335	COG1122	ATPase activity
EXW37_13340	COG4720	Psort location CytoplasmicMembrane, score
EXW37_13345	COG1794	racemase activity, acting on amino acids and derivatives
EXW37_13350	COG1819	glycosyl
EXW37_13360	COG0768	penicillin binding
EXW37_13365	COG5002	protein histidine kinase activity
EXW37_13370	COG0561	phosphatase activity
EXW37_13410	COG2124	cytochrome p450
EXW37_13460	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW37_13470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW37_13495	COG0577	efflux transmembrane transporter activity
EXW37_13500	COG1136	(ABC) transporter
EXW37_13515	COG0488	(ABC) transporter
EXW37_13520	COG0667	Aldo Keto reductase
EXW37_13525	COG0583	DNA-binding transcription factor activity
EXW37_13530	COG2205	protein histidine kinase activity
EXW37_13535	COG0745	RESPONSE REGULATOR receiver
EXW37_13545	COG3773	Cell wall hydrolase
EXW37_13550	COG0604	alcohol dehydrogenase
EXW37_13580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW37_13595	COG2959	enzyme of heme biosynthesis
EXW37_13625	COG3483	tryptophan 2,3-dioxygenase activity
EXW37_13630	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW37_13635	COG3844	kynureninase activity
EXW37_13640	COG1309	transcriptional regulator
EXW37_13670	COG1349	DNA-binding transcription factor activity
EXW37_13700	COG2223	nitrite transmembrane transporter activity
EXW37_13710	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_13715	COG0456	acetyltransferase
EXW37_13715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW37_13750	COG4176	ABC-type proline glycine betaine transport system permease component
EXW37_13755	COG4175	Glycine betaine
EXW37_13755	COG0517	IMP dehydrogenase activity
EXW37_13780	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW37_13785	COG2153	protein acetylation
EXW37_13790	COG3397	chitin binding
EXW37_13800	COG1819	glycosyl
EXW37_13815	COG2205	protein histidine kinase activity
EXW37_13820	COG2315	Protein conserved in bacteria
EXW37_13865	COG3973	AAA domain
EXW37_13880	COG2105	PFAM AIG2 family protein
EXW37_13885	COG0514	ATP-dependent DNA helicase (RecQ)
EXW37_13905	COG4637	Psort location Cytoplasmic, score
EXW37_13925	COG1227	inorganic diphosphatase activity
EXW37_13930	COG3397	chitin binding
EXW37_13935	COG2318	DinB family
EXW37_13950	COG1162	GTPase activity
EXW37_13955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW37_13960	COG1115	amino acid carrier protein
EXW37_13965	COG1012	belongs to the aldehyde dehydrogenase family
EXW37_13970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW37_13980	COG3938	Belongs to the proline racemase family
EXW37_13985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW37_14035	COG0586	Pfam SNARE associated Golgi protein
EXW37_14050	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW37_14055	COG4166	transmembrane transport
EXW37_14065	COG4948	Mandelate Racemase Muconate Lactonizing
EXW37_14085	COG0667	Aldo Keto reductase
EXW37_14130	COG2936	dipeptidyl-peptidase activity
EXW37_14140	COG0745	RESPONSE REGULATOR receiver
EXW37_14170	COG1164	Oligoendopeptidase f
EXW37_14190	COG1307	EDD domain protein, DegV family
EXW37_14220	COG1335	isochorismatase
EXW37_14235	COG2814	Major facilitator Superfamily
EXW37_14245	COG1664	Polymer-forming cytoskeletal
EXW37_14250	COG0789	Transcriptional regulator
EXW37_14255	COG4533	DNA binding
EXW37_14260	COG0477	Major facilitator Superfamily
EXW37_14260	COG2814	Major facilitator Superfamily
EXW37_14275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW37_14280	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW37_14285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW37_14290	COG0438	transferase activity, transferring glycosyl groups
EXW37_14305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW37_14310	COG0438	transferase activity, transferring glycosyl groups
EXW37_14315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW37_14330	COG2261	transglycosylase associated protein
EXW37_14345	COG2226	methyltransferase
EXW37_14380	COG0436	Aminotransferase
EXW37_14385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW37_14410	COG1131	(ABC) transporter
EXW37_14415	COG2188	Transcriptional regulator
EXW37_14460	COG0628	permease
EXW37_14490	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW37_14500	COG0697	spore germination
EXW37_14505	COG2318	DinB family
EXW37_14550	COG2814	Major facilitator Superfamily
EXW37_14555	COG1368	sulfuric ester hydrolase activity
EXW37_14565	COG0488	(ABC) transporter
EXW37_14570	COG2409	Drug exporters of the RND superfamily
EXW37_14570	COG1033	growth of symbiont in host cell
EXW37_14580	COG1309	transcriptional regulator
EXW37_14600	COG0287	Prephenate dehydrogenase
EXW37_14615	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW37_14615	COG1605	Chorismate mutase
EXW37_14665	COG3584	3D domain protein
EXW37_14665	COG1388	LysM domain
EXW37_14675	COG0346	lactoylglutathione lyase activity
EXW37_14710	COG0579	oxidoreductase
EXW37_14720	COG2390	Transcriptional regulator
EXW37_14740	COG1830	Aldolase
EXW37_14745	COG2226	methyltransferase
EXW37_14760	COG0346	lactoylglutathione lyase activity
EXW37_14765	COG2329	Antibiotic biosynthesis monooxygenase
EXW37_14785	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW37_14790	COG2207	Transcriptional regulator
EXW37_14795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW37_14800	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW37_14805	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW37_14810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW37_14815	COG3239	Fatty acid desaturase
EXW37_14835	COG3655	Transcriptional regulator
EXW37_14850	COG4377	Putative membrane peptidase family (DUF2324)
EXW37_14860	COG3279	Response regulator of the LytR AlgR family
EXW37_14875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW37_14880	COG0346	lactoylglutathione lyase activity
EXW37_14915	COG0714	Associated with various cellular activities
EXW37_14935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW37_14940	COG0753	catalase activity
EXW37_14950	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW37_14970	COG0778	Nitroreductase
EXW37_14975	COG1846	Transcriptional regulator
EXW37_14995	COG1051	belongs to the nudix hydrolase family
EXW37_15015	COG1725	Transcriptional regulator
EXW37_15050	COG2207	Transcriptional regulator
EXW37_15055	COG0456	acetyltransferase
EXW37_15070	COG0697	spore germination
EXW37_15075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW37_15080	COG1671	Belongs to the UPF0178 family
EXW37_15095	COG0642	Histidine kinase
EXW37_15100	COG0745	RESPONSE REGULATOR receiver
EXW37_15105	COG0596	Alpha beta hydrolase
EXW37_15115	COG0456	acetyltransferase
EXW37_15115	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW37_15140	COG0730	response to heat
EXW37_15150	COG0833	amino acid
EXW37_15160	COG4335	DNA alkylation repair
EXW37_15195	COG0768	penicillin binding
EXW37_15205	COG3104	oligopeptide transport
EXW37_15210	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW37_15225	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW37_15230	COG1984	allophanate hydrolase subunit 2
EXW37_15235	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW37_15240	COG1414	Transcriptional regulator
EXW37_15260	COG1960	acyl-CoA dehydrogenase activity
EXW37_15285	COG0640	Transcriptional regulator
EXW37_15305	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW37_15320	COG0574	Belongs to the PEP-utilizing enzyme family
EXW37_15320	COG3848	Pyruvate phosphate dikinase
EXW37_15345	COG1136	(ABC) transporter
EXW37_15380	COG1073	alpha beta
EXW37_15425	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW37_15445	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW37_15450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW37_15455	COG1121	(ABC) transporter
EXW37_15470	COG1999	signal sequence binding
EXW37_15475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW37_15480	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW37_15505	COG0798	PFAM Bile acid sodium symporter
EXW37_15510	COG0346	lactoylglutathione lyase activity
EXW37_15515	COG0640	Transcriptional regulator
EXW37_15565	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_15570	COG1522	sequence-specific DNA binding
EXW37_15585	COG0346	lactoylglutathione lyase activity
EXW37_15605	COG2226	methyltransferase
EXW37_15615	COG2814	Major facilitator Superfamily
EXW37_15640	COG0745	RESPONSE REGULATOR receiver
EXW37_15645	COG3850	Histidine kinase
EXW37_15645	COG5002	protein histidine kinase activity
EXW37_15675	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW37_15715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW37_15745	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW37_15765	COG1136	(ABC) transporter
EXW37_15770	COG0577	efflux transmembrane transporter activity
EXW37_15790	COG3850	Histidine kinase
EXW37_15790	COG5002	protein histidine kinase activity
EXW37_15805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW37_15825	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW37_15845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW37_15905	COG2814	Major facilitator Superfamily
EXW37_15925	COG1876	peptidase activity
EXW37_15930	COG2843	Capsule synthesis protein
EXW37_15945	COG0477	Major facilitator Superfamily
EXW37_15960	COG1846	Transcriptional regulator
EXW37_15965	COG2814	Major facilitator Superfamily
EXW37_15980	COG0789	Transcriptional regulator
EXW37_16015	COG1476	TRANSCRIPTIONal
EXW37_16030	COG1288	antiporter activity
EXW37_16035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW37_16150	COG4187	Peptidase family M20/M25/M40
EXW37_16155	COG1414	Transcriptional regulator
EXW37_16165	COG0833	amino acid
EXW37_16180	COG2031	fatty acid transporter
EXW37_16190	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW37_16245	COG2356	endonuclease I
EXW37_16250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW37_16270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW37_16290	COG1785	Belongs to the alkaline phosphatase family
EXW37_16295	COG0778	Nitroreductase
EXW37_16300	COG1733	regulation of RNA biosynthetic process
EXW37_16315	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_16325	COG1131	(ABC) transporter
EXW37_16355	COG1011	Hydrolase
EXW37_16360	COG2365	Tyrosine phosphatase family
EXW37_16385	COG0346	lactoylglutathione lyase activity
EXW37_16390	COG1940	carbohydrate kinase activity
EXW37_16395	COG0738	Major facilitator superfamily
EXW37_16400	COG0110	maltose O-acetyltransferase activity
EXW37_16415	COG0628	permease
EXW37_16420	COG2261	transglycosylase associated protein
EXW37_16450	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW37_16460	COG1253	flavin adenine dinucleotide binding
EXW37_16465	COG0789	Transcriptional regulator
EXW37_16470	COG0697	spore germination
EXW37_16475	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW37_16480	COG3813	Protein conserved in bacteria
EXW37_16485	COG2706	6-phosphogluconolactonase activity
EXW37_16490	COG1070	Carbohydrate kinase
EXW37_16500	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW37_16505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW37_16520	COG0814	amino acid
EXW37_16540	COG1393	Belongs to the ArsC family
EXW37_16550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW37_16565	COG0494	nUDIX hydrolase
EXW37_16590	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_16600	COG0318	PFAM AMP-dependent synthetase and ligase
EXW37_16605	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW37_16610	COG1733	regulation of RNA biosynthetic process
EXW37_16625	COG1191	sigma factor activity
EXW37_16655	COG1876	peptidase activity
EXW37_16680	COG0741	lytic transglycosylase activity
EXW37_16700	COG5002	protein histidine kinase activity
EXW37_16705	COG0745	RESPONSE REGULATOR receiver
EXW37_16725	COG0657	acetylesterase activity
EXW37_16735	COG2814	Major facilitator Superfamily
EXW37_16740	COG1309	transcriptional regulator
EXW37_16750	COG3226	Transcriptional regulator
EXW37_16755	COG1280	lysine exporter protein (LysE YggA)
EXW37_16785	COG0814	amino acid
EXW37_16810	COG1151	hydroxylamine reductase activity
EXW37_16855	COG2072	flavoprotein involved in K transport
EXW37_16900	COG1695	Transcriptional regulator
EXW37_16905	COG0604	alcohol dehydrogenase
EXW37_16910	COG1113	amino acid transport
EXW37_16920	COG2814	Major facilitator Superfamily
EXW37_16950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW37_16955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW37_16975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW37_16980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW37_16985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW37_16990	COG3739	integral membrane protein
EXW37_17015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW37_17020	COG0583	DNA-binding transcription factor activity
EXW37_17045	COG1193	negative regulation of DNA recombination
EXW37_17065	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW37_17070	COG1164	Oligoendopeptidase f
EXW37_17075	COG2957	Belongs to the agmatine deiminase family
EXW37_17095	COG3781	membrane
EXW37_17110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW37_17145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW37_17150	COG0640	Transcriptional regulator
EXW37_17155	COG0604	alcohol dehydrogenase
EXW37_17160	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW37_17170	COG0457	Tetratricopeptide repeat
EXW37_17175	COG2808	Putative FMN-binding domain
EXW37_17185	COG0277	FAD linked oxidase domain protein
EXW37_17205	COG1285	pathogenesis
EXW37_17220	COG2514	catechol 2,3-dioxygenase activity
EXW37_17225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW37_17230	COG1126	abc transporter atp-binding protein
EXW37_17235	COG0765	amino acid transport
EXW37_17240	COG2720	vancomycin resistance protein
EXW37_17265	COG1278	Cold shock
EXW37_17275	COG0716	FMN binding
EXW37_17285	COG0494	nUDIX hydrolase
EXW37_17305	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_17315	COG0165	Argininosuccinate lyase
EXW37_17330	COG4145	pantothenate transmembrane transporter activity
EXW37_17340	COG1012	belongs to the aldehyde dehydrogenase family
EXW37_17345	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_17355	COG1657	PFAM Prenyltransferase squalene oxidase
EXW37_17360	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW37_17365	COG2962	Rard protein
EXW37_17370	COG3326	Membrane
EXW37_17400	COG2226	methyltransferase
EXW37_17405	COG4166	transmembrane transport
EXW37_17410	COG4166	transmembrane transport
EXW37_17415	COG4166	transmembrane transport
EXW37_17425	COG1131	(ABC) transporter
EXW37_17445	COG0673	inositol 2-dehydrogenase activity
EXW37_17450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW37_17455	COG0187	DNA topoisomerase II activity
EXW37_17460	COG1832	CoA-binding protein
EXW37_17465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW37_17470	COG0745	RESPONSE REGULATOR receiver
EXW37_17480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW37_17480	COG1328	CTP reductase activity
EXW37_17490	COG4841	protein insertion into membrane
EXW37_17495	COG0824	Thioesterase
EXW37_17520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW37_17535	COG1266	CAAX protease self-immunity
EXW37_17540	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW37_17570	COG2211	Major facilitator Superfamily
EXW37_17580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW37_17595	COG0183	Belongs to the thiolase family
EXW37_17600	COG0318	PFAM AMP-dependent synthetase and ligase
EXW37_17605	COG1268	BioY protein
EXW37_17610	COG0318	PFAM AMP-dependent synthetase and ligase
EXW37_17615	COG1396	sequence-specific DNA binding
EXW37_17655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW37_17670	COG5002	protein histidine kinase activity
EXW37_17680	COG0400	carboxylic ester hydrolase activity
EXW37_17685	COG0346	lactoylglutathione lyase activity
EXW37_17695	COG0069	glutamate synthase activity
EXW37_17700	COG1902	pentaerythritol trinitrate reductase activity
EXW37_17705	COG1329	Transcriptional regulator
EXW37_17710	COG0010	Belongs to the arginase family
EXW37_17720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW37_17725	COG2986	histidine ammonia-lyase
EXW37_17735	COG2226	methyltransferase
EXW37_17765	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW37_17770	COG0785	Cytochrome C biogenesis protein
EXW37_17785	COG1473	amidohydrolase
EXW37_17790	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW37_17795	COG1131	(ABC) transporter
EXW37_17805	COG0583	DNA-binding transcription factor activity
EXW37_17815	COG1346	cytolysis
EXW37_17830	COG0730	response to heat
EXW37_17840	COG3409	Peptidoglycan-binding domain 1 protein
EXW37_17840	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW37_17860	COG1132	(ABC) transporter
EXW37_17865	COG1132	(ABC) transporter
EXW37_17870	COG3763	UPF0154 protein
EXW37_17890	COG3639	organic phosphonate transmembrane transporter activity
EXW37_17900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW37_17905	COG0737	Belongs to the 5'-nucleotidase family
EXW37_17915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW37_17920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW37_17935	COG1695	Transcriptional regulator
EXW37_17940	COG1132	(ABC) transporter
EXW37_17975	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW37_17985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW37_17990	COG3420	alginic acid biosynthetic process
EXW37_17990	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW37_18020	COG1216	Glycosyl transferase, family 2
EXW37_18040	COG0463	Glycosyl transferase, family 2
EXW37_18040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW37_18045	COG0438	transferase activity, transferring glycosyl groups
EXW37_18050	COG0438	transferase activity, transferring glycosyl groups
EXW37_18055	COG1086	Polysaccharide biosynthesis protein
EXW37_18060	COG0489	protein tyrosine kinase activity
EXW37_18065	COG3944	biosynthesis protein
EXW37_18105	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW37_18105	COG1388	LysM domain
EXW37_18105	COG3409	Peptidoglycan-binding domain 1 protein
EXW37_18110	COG4824	toxin secretion phage lysis holin
EXW37_18255	COG1595	DNA-templated transcription, initiation
EXW37_18395	COG0174	glutamine synthetase
EXW37_18400	COG0789	Transcriptional regulator
EXW37_18405	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW37_18410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW37_18415	COG2860	membrane
EXW37_18420	COG0464	growth
EXW37_18440	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW37_18450	COG3584	3D domain protein
EXW37_18450	COG1388	LysM domain
EXW37_18455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW37_18455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW37_18455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW37_18460	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW37_18465	COG1349	DNA-binding transcription factor activity
EXW37_18470	COG1979	alcohol dehydrogenase
EXW37_18475	COG2322	membrane
EXW37_18485	COG1113	amino acid transport
EXW37_18500	COG1473	amidohydrolase
EXW37_18505	COG1408	metallophosphoesterase
EXW37_18510	COG2116	formate transmembrane transporter activity
EXW37_18525	COG2217	Heavy metal translocating P-type atpase
EXW37_18530	COG2608	mercury ion transmembrane transporter activity
EXW37_18535	COG1937	Protein conserved in bacteria
EXW37_18570	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW37_18575	COG2819	hydrolase of the alpha beta superfamily
EXW37_18580	COG1120	ATPase activity
EXW37_18585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW37_18590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW37_18595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW37_18600	COG0708	Exodeoxyribonuclease III
EXW37_18605	COG2169	Transcriptional regulator
EXW37_18610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW37_18615	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW37_18625	COG2706	6-phosphogluconolactonase activity
EXW37_18630	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW37_18635	COG2364	Membrane
EXW37_18655	COG0346	lactoylglutathione lyase activity
EXW37_18660	COG3300	MHYT domain
EXW37_18660	COG5001	Diguanylate cyclase
EXW37_18700	COG1346	cytolysis
EXW37_18710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW37_18715	COG2945	thiolester hydrolase activity
EXW37_18715	COG0596	Alpha beta hydrolase
EXW37_18720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW37_18730	COG2188	Transcriptional regulator
EXW37_18735	COG2723	6-phospho-beta-galactosidase activity
EXW37_18740	COG0840	transmembrane signaling receptor activity
EXW37_18750	COG3773	Cell wall hydrolase
EXW37_18765	COG1368	sulfuric ester hydrolase activity
EXW37_18770	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW37_18785	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW37_18795	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW37_18800	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW37_18810	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW37_18815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW37_18820	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW37_18825	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW37_18825	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW37_18835	COG2359	stage V sporulation protein S
EXW37_18840	COG1692	metallophosphoesterase
EXW37_18845	COG1418	mRNA catabolic process
EXW37_18850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW37_18855	COG1058	Belongs to the CinA family
EXW37_18855	COG1546	Belongs to the CinA family
EXW37_18860	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW37_18865	COG1426	Protein conserved in bacteria
EXW37_18880	COG0300	oxidoreductase activity
EXW37_18885	COG0612	Peptidase, M16
EXW37_18890	COG0612	Peptidase, M16
EXW37_18895	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW37_18900	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW37_18905	COG3845	ABC transporter
EXW37_18910	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW37_18915	COG2188	Transcriptional regulator
EXW37_18920	COG1674	ftsk spoiiie
EXW37_18930	COG0740	serine-type endopeptidase activity
EXW37_18935	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW37_18945	COG0527	aspartate kinase activity
EXW37_18950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW37_18955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW37_18960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW37_18965	COG1873	PFAM PRC-barrel domain
EXW37_18970	COG0612	Peptidase, M16
EXW37_18975	COG0726	polysaccharide deacetylase
EXW37_18980	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW37_18990	COG0196	riboflavin kinase activity
EXW37_19000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW37_19005	COG1550	Protein conserved in bacteria
EXW37_19010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW37_19015	COG1358	cellular component organization or biogenesis
EXW37_19020	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW37_19025	COG0195	Participates in both transcription termination and antitermination
EXW37_19030	COG0779	Required for maturation of 30S ribosomal subunits
EXW37_19040	COG0442	prolyl-tRNA aminoacylation
EXW37_19045	COG0750	zinc metalloprotease
EXW37_19055	COG4589	Belongs to the CDS family
EXW37_19065	COG0233	cytoplasmic translational termination
EXW37_19070	COG0528	UMP kinase activity
EXW37_19075	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW37_19080	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW37_19085	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW37_19090	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW37_19095	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW37_19100	COG4974	Belongs to the 'phage' integrase family
EXW37_19105	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW37_19110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW37_19115	COG0758	DNA mediated transformation
EXW37_19120	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW37_19125	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW37_19130	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW37_19145	COG0335	large ribosomal subunit rRNA binding
EXW37_19150	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW37_19155	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW37_19160	COG1837	Belongs to the UPF0109 family
EXW37_19170	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW37_19175	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EXW37_19180	COG0552	protein localization to endoplasmic reticulum
EXW37_19185	COG1196	nuclear chromosome segregation
EXW37_19190	COG0571	ribonuclease III activity
EXW37_19195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW37_19200	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_19205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW37_19210	COG0416	fatty acid biosynthetic process
EXW37_19215	COG2050	protein possibly involved in aromatic compounds catabolism
EXW37_19215	COG1349	DNA-binding transcription factor activity
EXW37_19220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW37_19230	COG1461	Dihydroxyacetone kinase
EXW37_19235	COG1302	Protein conserved in bacteria
EXW37_19250	COG1564	THIamine pyrophosphokinase
EXW37_19255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW37_19265	COG2815	serine threonine protein kinase
EXW37_19265	COG0515	serine threonine protein kinase
EXW37_19270	COG0631	protein serine/threonine phosphatase activity
EXW37_19275	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW37_19280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW37_19280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW37_19285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW37_19290	COG0242	peptide deformylase activity
EXW37_19295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW37_19300	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW37_19305	COG1758	RNA polymerase activity
EXW37_19320	COG1561	YicC-like family, N-terminal region
EXW37_19325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW37_19340	COG0006	proline dipeptidase activity
EXW37_19400	COG0167	dihydroorotate dehydrogenase activity
EXW37_19405	COG0543	2 iron, 2 sulfur cluster binding
EXW37_19410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW37_19420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW37_19425	COG0540	Belongs to the ATCase OTCase family
EXW37_19435	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW37_19440	COG0564	pseudouridine synthase activity
EXW37_19445	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW37_19455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW37_19460	COG3599	regulation of cell shape
EXW37_19465	COG2302	S4 RNA-binding domain
EXW37_19470	COG0762	integral membrane protein
EXW37_19475	COG1799	cell septum assembly
EXW37_19480	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW37_19490	COG1873	PFAM PRC-barrel domain
EXW37_19495	COG1191	sigma factor activity
EXW37_19500	COG1191	sigma factor activity
EXW37_19510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW37_19515	COG0849	cell division
EXW37_19520	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW37_19535	COG0772	Belongs to the SEDS family
EXW37_19540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW37_19545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW37_19550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW37_19555	COG0768	penicillin binding
EXW37_19560	COG0768	penicillin binding
EXW37_19570	COG0275	rRNA processing
EXW37_19575	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW37_19580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW37_19585	COG0454	-acetyltransferase
EXW37_19595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW37_19600	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW37_19605	COG1323	Belongs to the UPF0348 family
EXW37_19610	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW37_19615	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW37_19620	COG3314	Sporulation integral membrane protein YlbJ
EXW37_19625	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EXW37_19630	COG0742	ribosomal rna small subunit methyltransferase
EXW37_19640	COG4471	UPF0298 protein
EXW37_19645	COG3679	Belongs to the UPF0342 family
EXW37_19650	COG0406	alpha-ribazole phosphatase activity
EXW37_19665	COG2340	Cysteine-rich secretory protein family
EXW37_19675	COG3336	cytochrome c oxidase
EXW37_19700	COG0109	protoheme IX farnesyltransferase activity
EXW37_19705	COG1612	heme a metabolic process
EXW37_19710	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW37_19720	COG0772	Belongs to the SEDS family
EXW37_19725	COG4838	Belongs to the UPF0358 family
EXW37_19730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW37_19735	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW37_19745	COG4896	Protein conserved in bacteria
EXW37_19760	COG1217	gtp-binding protein TYPA
EXW37_19770	COG0483	inositol monophosphate 1-phosphatase activity
EXW37_19780	COG4493	Belongs to the UPF0637 family
EXW37_19785	COG4476	Belongs to the UPF0223 family
EXW37_19795	COG1982	Orn Lys Arg decarboxylase major
EXW37_19840	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW37_19845	COG0022	dehydrogenase e1 component
EXW37_19850	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW37_19865	COG0561	phosphatase activity
EXW37_19875	COG5503	Protein of unknown function (DUF1447)
EXW37_19880	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW37_19885	COG0569	domain protein
EXW37_19895	COG1473	amidohydrolase
EXW37_19900	COG2171	N-acyltransferase activity
EXW37_19905	COG0583	DNA-binding transcription factor activity
EXW37_19910	COG0517	IMP dehydrogenase activity
EXW37_19920	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW37_19930	COG4703	Protein of unknown function (DUF1797)
EXW37_19945	COG2200	EAL domain
EXW37_19950	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_19955	COG1408	metallophosphoesterase
EXW37_20000	COG2814	Major facilitator Superfamily
EXW37_20010	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW37_20020	COG3209	COG3209 Rhs family protein
EXW37_20030	COG2205	protein histidine kinase activity
EXW37_20040	COG0436	Aminotransferase
EXW37_20045	COG1609	Transcriptional regulator
EXW37_20050	COG3833	ABC-type maltose transport systems, permease component
EXW37_20055	COG1175	transmembrane transport
EXW37_20060	COG2182	Extracellular solute-binding protein
EXW37_20070	COG0366	Alpha amylase catalytic
EXW37_20075	COG3842	ATPase activity
EXW37_20120	COG0183	Belongs to the thiolase family
EXW37_20155	COG1695	Transcriptional regulator
EXW37_20160	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_20170	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW37_20175	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW37_20180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW37_20185	COG0436	Aminotransferase
EXW37_20190	COG1850	ribulose-bisphosphate carboxylase activity
EXW37_20195	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW37_20200	COG0235	Class ii aldolase
EXW37_20205	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW37_20220	COG2084	Dehydrogenase
EXW37_20230	COG2199	diguanylate cyclase activity
EXW37_20235	COG0778	Nitroreductase
EXW37_20260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW37_20260	COG2190	(PTS) system
EXW37_20260	COG1263	PTS System
EXW37_20265	COG3711	transcriptional antiterminator
EXW37_20275	COG2188	Transcriptional regulator
EXW37_20280	COG0363	glucosamine-6-phosphate deaminase activity
EXW37_20295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW37_20305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW37_20315	COG1547	Domain of unknown function (DUF309)
EXW37_20325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW37_20330	COG4086	secreted protein
EXW37_20335	COG0561	phosphatase activity
EXW37_20340	COG0697	spore germination
EXW37_20355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW37_20380	COG0733	neurotransmitter:sodium symporter activity
EXW37_20400	COG1686	Belongs to the peptidase S11 family
EXW37_20405	COG1725	Transcriptional regulator
EXW37_20410	COG1131	(ABC) transporter
EXW37_20430	COG1846	Transcriptional regulator
EXW37_20445	COG0598	Magnesium transport protein CorA
EXW37_20460	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW37_20470	COG4974	Belongs to the 'phage' integrase family
EXW37_20480	COG0735	belongs to the Fur family
EXW37_20485	COG1300	Membrane
EXW37_20505	COG0667	Aldo Keto reductase
EXW37_20510	COG0656	L-ascorbic acid biosynthetic process
EXW37_20515	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW37_20515	COG0456	acetyltransferase
EXW37_20525	COG0737	Belongs to the 5'-nucleotidase family
EXW37_20525	COG1525	nuclease
EXW37_20525	COG4085	toxin activity
EXW37_20530	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW37_20540	COG0596	Alpha beta hydrolase
EXW37_20545	COG2056	Na+-H+ antiporter family
EXW37_20550	COG1609	Transcriptional regulator
EXW37_20555	COG0456	acetyltransferase
EXW37_20560	COG1073	alpha beta
EXW37_20575	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW37_20575	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW37_20580	COG0307	riboflavin synthase, alpha
EXW37_20585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW37_20585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW37_20600	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW37_20605	COG4106	trans-aconitate 2-methyltransferase activity
EXW37_20610	COG2226	methyltransferase
EXW37_20610	COG1073	alpha beta
EXW37_20615	COG0156	8-amino-7-oxononanoate synthase activity
EXW37_20625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW37_20640	COG1757	Na H antiporter
EXW37_20645	COG0737	Belongs to the 5'-nucleotidase family
EXW37_20655	COG1522	sequence-specific DNA binding
EXW37_20680	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW37_20690	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW37_20705	COG0300	oxidoreductase activity
EXW37_20710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW37_20715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW37_20720	COG1760	l-serine dehydratase
EXW37_20725	COG1760	l-serine dehydratase
EXW37_20735	COG1234	tRNA 3'-trailer cleavage
EXW37_20770	COG1131	(ABC) transporter
EXW37_20795	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW37_20800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW37_20810	COG1376	ErfK ybiS ycfS ynhG family protein
EXW37_20815	COG4129	membrane
EXW37_20820	COG1126	abc transporter atp-binding protein
EXW37_20825	COG0765	amino acid transport
EXW37_20830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW37_20845	COG2323	membrane
EXW37_20850	COG0772	Belongs to the SEDS family
EXW37_20860	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW37_20865	COG0022	dehydrogenase e1 component
EXW37_20870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW37_20875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW37_20880	COG3426	butyrate kinase activity
EXW37_20890	COG0280	phosphate acetyltransferase
EXW37_20900	COG3290	protein histidine kinase activity
EXW37_20900	COG3829	transcription factor binding
EXW37_20910	COG0584	glycerophosphoryl diester phosphodiesterase
EXW37_20915	COG3093	addiction module antidote protein HigA
EXW37_20925	COG0745	RESPONSE REGULATOR receiver
EXW37_20935	COG0750	zinc metalloprotease
EXW37_20940	COG0497	DNA recombination
EXW37_20945	COG1438	arginine binding
EXW37_20950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW37_20955	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW37_20960	COG0142	geranyltranstransferase activity
EXW37_20965	COG1722	exodeoxyribonuclease VII activity
EXW37_20970	COG1570	exodeoxyribonuclease VII activity
EXW37_20975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW37_20980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW37_20985	COG1302	Protein conserved in bacteria
EXW37_20990	COG0439	Biotin carboxylase
EXW37_20995	COG0511	ligase activity, forming carbon-carbon bonds
EXW37_21040	COG3854	ATPases associated with a variety of cellular activities
EXW37_21060	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW37_21065	COG0006	proline dipeptidase activity
EXW37_21070	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW37_21080	COG3872	metal-dependent enzyme
EXW37_21090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW37_21095	COG1321	iron dependent repressor
EXW37_21125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW37_21135	COG1609	Transcriptional regulator
EXW37_21145	COG2076	Multidrug Resistance protein
EXW37_21150	COG2076	Multidrug Resistance protein
EXW37_21185	COG1725	Transcriptional regulator
EXW37_21200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW37_21205	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW37_21210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW37_21215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW37_21245	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW37_21270	COG4970	Tfp pilus assembly protein FimT
EXW37_21280	COG1459	type II secretion system
EXW37_21285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW37_21340	COG0646	methionine synthase
EXW37_21340	COG1410	methionine synthase
EXW37_21345	COG0646	methionine synthase
EXW37_21345	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW37_21350	COG0626	cystathionine gamma-synthase activity
EXW37_21355	COG0626	cystathionine gamma-synthase activity
EXW37_21370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW37_21380	COG1940	carbohydrate kinase activity
EXW37_21385	COG4483	Protein conserved in bacteria
EXW37_21390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW37_21395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW37_21400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW37_21405	COG0704	Plays a role in the regulation of phosphate uptake
EXW37_21420	COG0581	inorganic phosphate transmembrane transporter activity
EXW37_21425	COG0573	inorganic phosphate transmembrane transporter activity
EXW37_21430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW37_21435	COG0768	penicillin binding
EXW37_21440	COG0477	Major facilitator Superfamily
EXW37_21445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW37_21470	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW37_21475	COG0735	belongs to the Fur family
EXW37_21480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW37_21485	COG1121	(ABC) transporter
EXW37_21490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW37_21500	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW37_21515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW37_21520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW37_21525	COG2384	SAM-dependent methyltransferase
EXW37_21535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW37_21540	COG0358	DNA primase activity
EXW37_21550	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW37_21555	COG0517	IMP dehydrogenase activity
EXW37_21560	COG1381	Involved in DNA repair and RecF pathway recombination
EXW37_21570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW37_21575	COG0295	cytidine deaminase activity
EXW37_21580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW37_21585	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW37_21590	COG1480	7TM receptor with intracellular HD hydrolase
EXW37_21595	COG1702	phosphate starvation-inducible protein PhoH
EXW37_21610	COG1610	YqeY-like protein
EXW37_21615	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW37_21620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW37_21625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW37_21635	COG0484	heat shock protein binding
EXW37_21640	COG0443	Heat shock 70 kDa protein
EXW37_21650	COG1420	regulation of RNA biosynthetic process
EXW37_21655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW37_21660	COG1733	regulation of RNA biosynthetic process
EXW37_21665	COG0481	GTPase activity
EXW37_21675	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW37_21680	COG0268	Binds directly to 16S ribosomal RNA
EXW37_21685	COG1466	dna polymerase III delta subunit
EXW37_21695	COG2333	competence protein COMEC
EXW37_21695	COG0658	competence protein
EXW37_21700	COG2131	deaminase
EXW37_21705	COG1555	photosystem II stabilization
EXW37_21705	COG1596	polysaccharide export
EXW37_21710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW37_21715	COG2226	methyltransferase
EXW37_21720	COG0799	negative regulation of ribosome biogenesis
EXW37_21725	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW37_21730	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW37_21735	COG1534	Rna-binding protein
EXW37_21740	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW37_21745	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW37_21750	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW37_21760	COG0688	phosphatidylethanolamine metabolic process
EXW37_21770	COG1595	DNA-templated transcription, initiation
EXW37_21775	COG2357	RelA SpoT domain protein
EXW37_21785	COG1785	Belongs to the alkaline phosphatase family
EXW37_21795	COG2267	carboxylic ester hydrolase activity
EXW37_21830	COG1404	Belongs to the peptidase S8 family
EXW37_21835	COG3186	Phenylalanine-4-hydroxylase
EXW37_21840	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW37_21845	COG2514	catechol 2,3-dioxygenase activity
EXW37_21850	COG2259	Doxx family
EXW37_21890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW37_21900	COG1012	belongs to the aldehyde dehydrogenase family
EXW37_21900	COG1454	alcohol dehydrogenase
EXW37_21905	COG0626	cystathionine gamma-synthase activity
EXW37_21910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW37_21915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW37_21920	COG2226	methyltransferase
EXW37_21935	COG0768	penicillin binding
EXW37_21940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW37_21945	COG0572	uridine kinase
EXW37_21950	COG0826	peptidase U32
EXW37_21955	COG0826	peptidase U32
EXW37_21960	COG4122	O-methyltransferase activity
EXW37_21965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW37_21975	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW37_21980	COG4472	Bacterial protein of unknown function (DUF965)
EXW37_21985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW37_21995	COG0628	permease
EXW37_22015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW37_22025	COG0482	sulfurtransferase activity
EXW37_22030	COG1104	cysteine desulfurase activity
EXW37_22035	COG1959	2 iron, 2 sulfur cluster binding
EXW37_22040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW37_22055	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW37_22060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW37_22070	COG1490	D-aminoacyl-tRNA deacylase activity
EXW37_22075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW37_22080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW37_22085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW37_22085	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW37_22090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW37_22095	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW37_22095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW37_22105	COG2244	polysaccharide biosynthetic process
EXW37_22110	COG2323	membrane
EXW37_22120	COG1862	Preprotein translocase
EXW37_22125	COG0343	queuine tRNA-ribosyltransferase activity
EXW37_22130	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW37_22140	COG2255	four-way junction helicase activity
EXW37_22145	COG0632	four-way junction helicase activity
EXW37_22150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW37_22175	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW37_22180	COG0157	Belongs to the NadC ModD family
EXW37_22185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW37_22190	COG1104	cysteine desulfurase activity
EXW37_22195	COG1827	regulation of RNA biosynthetic process
EXW37_22200	COG2258	MOSC domain
EXW37_22205	COG0077	Prephenate dehydratase
EXW37_22210	COG0577	efflux transmembrane transporter activity
EXW37_22215	COG0577	efflux transmembrane transporter activity
EXW37_22220	COG1136	(ABC) transporter
EXW37_22225	COG5002	protein histidine kinase activity
EXW37_22230	COG0745	RESPONSE REGULATOR receiver
EXW37_22235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW37_22240	COG3290	protein histidine kinase activity
EXW37_22250	COG2868	ribosomal protein
EXW37_22260	COG1530	ribonuclease E activity
EXW37_22265	COG1994	Peptidase M50
EXW37_22270	COG0739	heme binding
EXW37_22275	COG2894	cell division
EXW37_22280	COG0850	regulation of cytokinetic process
EXW37_22295	COG1077	Cell shape determining protein MreB Mrl
EXW37_22330	COG2003	Belongs to the UPF0758 family
EXW37_22335	COG0424	maF-like protein
EXW37_22350	COG0285	dihydrofolate synthase activity
EXW37_22365	COG1388	LysM domain
EXW37_22370	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW37_22375	COG0113	porphobilinogen synthase activity
EXW37_22380	COG1587	Uroporphyrinogen-III synthase
EXW37_22385	COG0181	hydroxymethylbilane synthase activity
EXW37_22390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW37_22395	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW37_22400	COG1846	Transcriptional regulator
EXW37_22405	COG1764	response to oxidative stress
EXW37_22410	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW37_22420	COG1067	ATP-dependent peptidase activity
EXW37_22420	COG0470	DNA polymerase III
EXW37_22430	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW37_22460	COG0622	Phosphoesterase
EXW37_22470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW37_22475	COG5401	PFAM Sporulation and spore germination
EXW37_22485	COG0477	Major facilitator Superfamily
EXW37_22495	COG1309	transcriptional regulator
EXW37_22505	COG2197	response regulator
EXW37_22510	COG2233	PERMEase
EXW37_22515	COG0402	S-adenosylhomocysteine deaminase activity
EXW37_22520	COG1983	PspC domain protein
EXW37_22525	COG1396	sequence-specific DNA binding
EXW37_22530	COG0697	spore germination
EXW37_22540	COG1959	2 iron, 2 sulfur cluster binding
EXW37_22545	COG1668	transmembrane transport
EXW37_22550	COG4152	abc transporter atp-binding protein
EXW37_22555	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW37_22560	COG1360	Flagellar Motor Protein
EXW37_22565	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW37_22575	COG1876	peptidase activity
EXW37_22580	COG0824	Thioesterase
EXW37_22585	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW37_22590	COG1053	succinate dehydrogenase
EXW37_22595	COG2009	succinate dehydrogenase
EXW37_22600	COG1719	4-vinyl reductase, 4VR
EXW37_22605	COG0322	excinuclease ABC activity
EXW37_22610	COG3118	belongs to the thioredoxin family
EXW37_22615	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW37_22620	COG2086	electron transfer activity
EXW37_22625	COG1024	Enoyl-CoA hydratase
EXW37_22630	COG1309	transcriptional regulator
EXW37_22635	COG0318	PFAM AMP-dependent synthetase and ligase
EXW37_22660	COG2318	DinB family
EXW37_22685	COG1131	(ABC) transporter
EXW37_22690	COG2205	protein histidine kinase activity
EXW37_22695	COG0745	RESPONSE REGULATOR receiver
EXW37_22700	COG4895	conserved protein (DUF2196)
EXW37_22705	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW37_22710	COG2329	Antibiotic biosynthesis monooxygenase
EXW37_22715	COG4509	Sortase family
EXW37_22720	COG1120	ATPase activity
EXW37_22735	COG5386	Cell surface protein
EXW37_22745	COG5386	Cell surface protein
EXW37_22750	COG1114	Component of the transport system for branched-chain amino acids
EXW37_22760	COG1193	negative regulation of DNA recombination
EXW37_22765	COG1796	DNA polymerase
EXW37_22765	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW37_22770	COG1286	toxin biosynthetic process
EXW37_22775	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW37_22780	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW37_22805	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW37_22810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW37_22825	COG1418	mRNA catabolic process
EXW37_22855	COG2814	Major facilitator Superfamily
EXW37_22860	COG1566	PFAM secretion protein HlyD family protein
EXW37_22865	COG1309	transcriptional regulator
EXW37_22870	COG1363	Peptidase, m42
EXW37_22880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW37_22895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW37_22905	COG1484	DNA-dependent DNA replication
EXW37_22910	COG3611	Membrane attachment protein
EXW37_22915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW37_22920	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW37_22925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW37_22930	COG0237	dephospho-CoA kinase activity
EXW37_22935	COG1971	Probably functions as a manganese efflux pump
EXW37_22945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW37_22945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW37_22950	COG5002	protein histidine kinase activity
EXW37_22955	COG0745	RESPONSE REGULATOR receiver
EXW37_22970	COG0039	L-malate dehydrogenase activity
EXW37_22975	COG0538	isocitrate dehydrogenase activity
EXW37_22980	COG0372	Belongs to the citrate synthase family
EXW37_22995	COG0628	permease
EXW37_23000	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW37_23010	COG0205	6-phosphofructokinase activity
EXW37_23020	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW37_23025	COG1725	Transcriptional regulator
EXW37_23030	COG0281	malic enzyme
EXW37_23035	COG0587	DNA-directed DNA polymerase activity
EXW37_23050	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW37_23070	COG4109	DRTGG domain
EXW37_23075	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW37_23080	COG0006	proline dipeptidase activity
EXW37_23110	COG0662	Cupin 2, conserved barrel domain protein
EXW37_23115	COG1476	TRANSCRIPTIONal
EXW37_23130	COG1028	Short-chain dehydrogenase reductase Sdr
EXW37_23135	COG0589	response to stress
EXW37_23155	COG0165	Argininosuccinate lyase
EXW37_23160	COG0137	argininosuccinate synthase activity
EXW37_23175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW37_23190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW37_23195	COG0827	DNA restriction-modification system
EXW37_23200	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW37_23205	COG3874	Sporulation protein YtfJ
EXW37_23220	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW37_23230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW37_23245	COG1104	cysteine desulfurase activity
EXW37_23250	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW37_23265	COG1309	transcriptional regulator
EXW37_23270	COG1956	GAF domain-containing protein
EXW37_23275	COG0626	cystathionine gamma-synthase activity
EXW37_23280	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW37_23305	COG1595	DNA-templated transcription, initiation
EXW37_23315	COG0110	maltose O-acetyltransferase activity
EXW37_23320	COG0456	acetyltransferase
EXW37_23325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW37_23330	COG0454	-acetyltransferase
EXW37_23335	COG0517	IMP dehydrogenase activity
EXW37_23340	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW37_23355	COG0745	RESPONSE REGULATOR receiver
EXW37_23360	COG5002	protein histidine kinase activity
EXW37_23365	COG0666	response to abiotic stimulus
EXW37_23375	COG1970	mechanosensitive ion channel activity
EXW37_23395	COG1609	Transcriptional regulator
EXW37_23405	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW37_23405	COG1605	Chorismate mutase
EXW37_23410	COG4851	CamS sex pheromone cAM373 precursor
EXW37_23415	COG3118	belongs to the thioredoxin family
EXW37_23450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW37_23460	COG1674	ftsk spoiiie
EXW37_23475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW37_23480	COG4848	Belongs to the UPF0354 family
EXW37_23485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW37_23490	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW37_23495	COG1363	Peptidase, m42
EXW37_23505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW37_23510	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW37_23520	COG0510	thiamine kinase activity
EXW37_23525	COG1523	belongs to the glycosyl hydrolase 13 family
EXW37_23535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW37_23540	COG1349	DNA-binding transcription factor activity
EXW37_23545	COG1187	pseudouridine synthase activity
EXW37_23550	COG2244	polysaccharide biosynthetic process
EXW37_23555	COG2081	HI0933 family
EXW37_23560	COG2814	Major facilitator Superfamily
EXW37_23570	COG3832	glyoxalase III activity
EXW37_23590	COG1329	Transcriptional regulator
EXW37_23615	COG0314	molybdopterin synthase activity
EXW37_23620	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW37_23625	COG0303	'Molybdopterin
EXW37_23630	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW37_23635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW37_23640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW37_23665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW37_23675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW37_23715	COG0495	leucyl-tRNA aminoacylation
EXW37_23720	COG2814	Major facilitator Superfamily
EXW37_23725	COG0475	glutathione-regulated potassium exporter activity
EXW37_23730	COG0490	domain, Protein
EXW37_23735	COG0582	viral genome integration into host DNA
EXW37_23750	COG1136	(ABC) transporter
EXW37_23775	COG1242	4 iron, 4 sulfur cluster binding
EXW37_23780	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW37_23790	COG1794	racemase activity, acting on amino acids and derivatives
EXW37_23805	COG2267	carboxylic ester hydrolase activity
EXW37_23810	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW37_23815	COG0671	phosphoesterase, PA-phosphatase related
EXW37_23820	COG0438	transferase activity, transferring glycosyl groups
EXW37_23845	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW37_23850	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW37_23875	COG5002	protein histidine kinase activity
EXW37_23880	COG3852	Histidine kinase
EXW37_23885	COG0753	catalase activity
EXW37_23890	COG2267	carboxylic ester hydrolase activity
EXW37_23895	COG1368	sulfuric ester hydrolase activity
EXW37_23900	COG4895	conserved protein (DUF2196)
EXW37_23915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW37_23920	COG1116	anion transmembrane transporter activity
EXW37_23925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW37_23950	COG0494	nUDIX hydrolase
EXW37_23995	COG2076	Multidrug Resistance protein
EXW37_24000	COG2076	Multidrug Resistance protein
EXW37_24005	COG0789	Transcriptional regulator
EXW37_24010	COG1854	S-ribosylhomocysteine lyase activity
EXW37_24020	COG0288	reversible hydration of carbon dioxide
EXW37_24025	COG1271	oxidase subunit
EXW37_24030	COG1294	oxidase, subunit
EXW37_24050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW37_24075	COG1842	Phage shock protein A
EXW37_24105	COG5002	protein histidine kinase activity
EXW37_24110	COG0745	RESPONSE REGULATOR receiver
EXW37_24135	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW37_24140	COG1597	lipid kinase activity
EXW37_24155	COG1136	(ABC) transporter
EXW37_24185	COG5002	protein histidine kinase activity
EXW37_24195	COG0586	Pfam SNARE associated Golgi protein
EXW37_24210	COG0577	efflux transmembrane transporter activity
EXW37_24215	COG1136	(ABC) transporter
EXW37_24220	COG2207	Transcriptional regulator
EXW37_24220	COG3708	Transcriptional regulator
EXW37_24230	COG1131	(ABC) transporter
EXW37_24235	COG5658	integral membrane protein
EXW37_24240	COG0640	Transcriptional regulator
EXW37_24245	COG0745	RESPONSE REGULATOR receiver
EXW37_24250	COG2205	protein histidine kinase activity
EXW37_24255	COG0577	efflux transmembrane transporter activity
EXW37_24260	COG0577	efflux transmembrane transporter activity
EXW37_24265	COG1136	(ABC) transporter
EXW37_24270	COG0577	efflux transmembrane transporter activity
EXW37_24285	COG2188	Transcriptional regulator
EXW37_24305	COG3964	amidohydrolase
EXW37_24325	COG4948	Mandelate Racemase Muconate Lactonizing
EXW37_24330	COG0318	PFAM AMP-dependent synthetase and ligase
EXW37_24335	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW37_24340	COG0596	Alpha beta hydrolase
EXW37_24345	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW37_24350	COG1169	isochorismate synthase
EXW37_24355	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW37_24360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW37_24365	COG1278	Cold shock
EXW37_24385	COG0058	SHG alpha-glucan phosphorylase activity
EXW37_24395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW37_24400	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW37_24405	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW37_24420	COG1309	transcriptional regulator
EXW37_24555	COG1285	pathogenesis
EXW37_24560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW37_24570	COG0166	Belongs to the GPI family
EXW37_24580	COG2155	Conserved Protein
EXW37_24585	COG1098	S1 RNA binding domain
EXW37_24590	COG0436	Aminotransferase
EXW37_24595	COG1522	sequence-specific DNA binding
EXW37_24600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW37_24605	COG2267	carboxylic ester hydrolase activity
EXW37_24615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW37_24630	COG5018	Exonuclease
EXW37_24635	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW37_24655	COG2050	protein possibly involved in aromatic compounds catabolism
EXW37_24665	COG1268	BioY protein
EXW37_24670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW37_24675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW37_24685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW37_24690	COG3584	3D domain protein
EXW37_24705	COG1252	NADH dehydrogenase
EXW37_24710	COG0492	ferredoxin-NADP+ reductase activity
EXW37_24730	COG1683	Conserved Protein
EXW37_24755	COG0316	Belongs to the HesB IscA family
EXW37_24760	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW37_24765	COG4844	belongs to the
EXW37_24770	COG1252	NADH dehydrogenase
EXW37_24780	COG0390	transport system, permease component
EXW37_24785	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW37_24825	COG4837	Protein of unknown function (DUF1462)
EXW37_24830	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW37_24840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW37_24845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW37_24870	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW37_24880	COG0647	UMP catabolic process
EXW37_24890	COG2445	Protein of unknown function DUF86
EXW37_24895	COG1494	fructose-1,6-bisphosphatase
EXW37_24910	COG4470	Protein conserved in bacteria
EXW37_24920	COG0789	Transcriptional regulator
EXW37_24925	COG4377	Putative membrane peptidase family (DUF2324)
EXW37_24945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW37_24950	COG0739	heme binding
EXW37_24960	COG3377	Domain of unknown function (DUF1805)
EXW37_24965	COG0737	Belongs to the 5'-nucleotidase family
EXW37_24970	COG1695	Transcriptional regulator
EXW37_24980	COG0719	Fe-S assembly protein
EXW37_24985	COG0822	iron-sulfur transferase activity
EXW37_24990	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW37_24995	COG0719	Fe-S assembly protein
EXW37_25000	COG0396	ATPase activity
EXW37_25005	COG1464	Belongs to the NlpA lipoprotein family
EXW37_25010	COG1464	Belongs to the NlpA lipoprotein family
EXW37_25015	COG2011	ABC-type metal ion transport system permease component
EXW37_25020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW37_25030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW37_25035	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW37_25040	COG0509	glycine decarboxylation via glycine cleavage system
EXW37_25045	COG1393	Belongs to the ArsC family
EXW37_25090	COG1309	transcriptional regulator
EXW37_25095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW37_25100	COG1960	acyl-CoA dehydrogenase activity
EXW37_25105	COG0183	Belongs to the thiolase family
EXW37_25110	COG1024	Enoyl-CoA hydratase
EXW37_25110	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW37_25120	COG1686	Belongs to the peptidase S11 family
EXW37_25125	COG0506	proline dehydrogenase activity
EXW37_25135	COG0011	TIGRFAM Protein of
EXW37_25140	COG0840	transmembrane signaling receptor activity
EXW37_25155	COG2814	Major facilitator Superfamily
EXW37_25160	COG0531	amino acid
EXW37_25185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW37_25220	COG0586	Pfam SNARE associated Golgi protein
EXW37_25230	COG1376	ErfK ybiS ycfS ynhG family protein
EXW37_25235	COG0745	RESPONSE REGULATOR receiver
EXW37_25240	COG5002	protein histidine kinase activity
EXW37_25250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW37_25260	COG0840	transmembrane signaling receptor activity
EXW37_25265	COG0840	transmembrane signaling receptor activity
EXW37_25270	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW37_25275	COG3227	Zinc metalloprotease (Elastase)
EXW37_25280	COG1741	Belongs to the pirin family
EXW37_25295	COG0586	Pfam SNARE associated Golgi protein
EXW37_25300	COG0475	glutathione-regulated potassium exporter activity
EXW37_25305	COG0490	domain, Protein
EXW37_25310	COG1115	amino acid carrier protein
EXW37_25315	COG0783	Belongs to the Dps family
EXW37_25325	COG2318	DinB family
EXW37_25335	COG1611	Belongs to the LOG family
EXW37_25345	COG1528	Iron-storage protein
EXW37_25350	COG2311	Membrane
EXW37_25355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW37_25360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW37_25365	COG1115	amino acid carrier protein
EXW37_25370	COG2910	NAD(P)H-binding
EXW37_25385	COG0656	L-ascorbic acid biosynthetic process
EXW37_25390	COG2814	Major facilitator Superfamily
EXW37_25395	COG1733	regulation of RNA biosynthetic process
EXW37_25405	COG1252	NADH dehydrogenase
EXW37_25425	COG0840	transmembrane signaling receptor activity
EXW37_25425	COG3290	protein histidine kinase activity
EXW37_25460	COG0488	(ABC) transporter
EXW37_25465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW37_25475	COG1733	regulation of RNA biosynthetic process
EXW37_25480	COG0778	Nitroreductase
EXW37_25485	COG4224	UPF0291 protein
EXW37_25490	COG1335	isochorismatase
EXW37_25495	COG1522	sequence-specific DNA binding
EXW37_25505	COG1522	sequence-specific DNA binding
EXW37_25510	COG0288	reversible hydration of carbon dioxide
EXW37_25515	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW37_25520	COG2233	PERMEase
EXW37_25560	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW37_25565	COG0557	exoribonuclease II activity
EXW37_25570	COG1647	Serine aminopeptidase, S33
EXW37_25575	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW37_25580	COG1346	cytolysis
EXW37_25595	COG0148	phosphopyruvate hydratase activity
EXW37_25605	COG0149	triose-phosphate isomerase activity
EXW37_25610	COG0126	phosphoglycerate kinase activity
EXW37_25615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW37_25630	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW37_25660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW37_25675	COG2323	membrane
EXW37_25690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW37_25695	COG1481	regulation of sporulation
EXW37_25700	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW37_25705	COG1660	Displays ATPase and GTPase activities
EXW37_25710	COG1051	belongs to the nudix hydrolase family
EXW37_25720	COG0492	ferredoxin-NADP+ reductase activity
EXW37_25725	COG0457	Tetratricopeptide repeat
EXW37_25730	COG0110	maltose O-acetyltransferase activity
EXW37_25735	COG0546	phosphoglycolate phosphatase activity
EXW37_25740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW37_25745	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW37_25750	COG1950	PFAM Membrane protein of
EXW37_25755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW37_25760	COG0556	nucleotide-excision repair
EXW37_25775	COG0789	Transcriptional regulator
EXW37_25810	COG0583	DNA-binding transcription factor activity
EXW37_25815	COG0789	Transcriptional regulator
EXW37_25820	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW37_25825	COG0488	(ABC) transporter
EXW37_25835	COG1132	(ABC) transporter
EXW37_25840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW37_25845	COG0793	Belongs to the peptidase S41A family
EXW37_25845	COG3409	Peptidoglycan-binding domain 1 protein
EXW37_25850	COG2177	Part of the ABC transporter FtsEX involved in
EXW37_25855	COG2884	Cell division ATP-binding protein ftsE
EXW37_25890	COG1131	(ABC) transporter
EXW37_25920	COG1278	Cold shock
EXW37_25925	COG1040	competence protein
EXW37_25930	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW37_25935	COG1388	LysM domain
EXW37_25935	COG0791	NLP P60 protein
EXW37_25940	COG1733	regulation of RNA biosynthetic process
EXW37_25945	COG1307	EDD domain protein, DegV family
EXW37_25950	COG1739	Uncharacterized protein family UPF0029
EXW37_25955	COG1316	TRANSCRIPTIONal
EXW37_25960	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW37_25965	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW37_25970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW37_25980	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW37_25980	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW37_26000	COG1486	melibiose metabolic process
EXW37_26005	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW37_26010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW37_26030	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW37_26040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW37_26045	COG1301	dicarboxylic acid transport
EXW37_26060	COG1511	domain protein
EXW37_26065	COG0583	DNA-binding transcription factor activity
EXW37_26070	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW37_26075	COG1271	oxidase subunit
EXW37_26080	COG1294	oxidase, subunit
EXW37_26085	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW37_26090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW37_26095	COG1620	l-lactate permease
EXW37_26105	COG2389	metal-binding protein
EXW37_26120	COG1368	sulfuric ester hydrolase activity
EXW37_26130	COG1388	LysM domain
EXW37_26130	COG0791	NLP P60 protein
EXW37_26135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW37_26145	COG1215	transferase activity, transferring glycosyl groups
EXW37_26150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW37_26160	COG3584	3D domain protein
EXW37_26160	COG1388	LysM domain
EXW37_26185	COG4715	Zinc finger, swim domain protein
EXW37_26190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW37_26230	COG0577	efflux transmembrane transporter activity
EXW37_26235	COG1136	(ABC) transporter
EXW37_26270	COG3850	Histidine kinase
EXW37_26270	COG5002	protein histidine kinase activity
EXW37_26275	COG0745	RESPONSE REGULATOR receiver
EXW37_26280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW37_26295	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW37_26310	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW37_26340	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW37_26355	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW37_26370	COG0110	maltose O-acetyltransferase activity
EXW37_26395	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW37_26400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW37_26405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW37_26410	COG4464	protein tyrosine phosphatase activity
EXW37_26415	COG0489	protein tyrosine kinase activity
EXW37_26420	COG3944	biosynthesis protein
EXW37_26425	COG0489	protein tyrosine kinase activity
EXW37_26440	COG1609	Transcriptional regulator
EXW37_26450	COG0739	heme binding
EXW37_26465	COG3279	Response regulator of the LytR AlgR family
EXW37_26470	COG2385	sporulation resulting in formation of a cellular spore
EXW37_26485	COG4836	Membrane
EXW37_26490	COG1007	ATP synthesis coupled electron transport
EXW37_26495	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW37_26500	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW37_26505	COG0713	ATP synthesis coupled electron transport
EXW37_26510	COG0839	Belongs to the complex I subunit 6 family
EXW37_26520	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW37_26525	COG0649	NAD binding
EXW37_26530	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW37_26535	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW37_26540	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW37_26545	COG5001	Diguanylate cyclase
EXW37_26545	COG3300	MHYT domain
EXW37_26560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW37_26565	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW37_26570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW37_26575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW37_26580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW37_26585	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW37_26595	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW37_26620	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW37_26630	COG0698	ribose 5-phosphate isomerase
EXW37_26640	COG2190	(PTS) system
EXW37_26645	COG2259	Doxx family
EXW37_26650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW37_26660	COG1971	Probably functions as a manganese efflux pump
EXW37_26665	COG0009	L-threonylcarbamoyladenylate synthase
EXW37_26680	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW37_26685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW37_26695	COG1435	thymidine kinase activity
EXW37_26710	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW37_26720	COG1494	fructose-1,6-bisphosphatase
EXW37_26740	COG4821	SIS domain
EXW37_26745	COG0504	CTP synthase activity
EXW37_26750	COG3343	RNA polymerase activity
EXW37_26760	COG1960	acyl-CoA dehydrogenase activity
EXW37_26765	COG1960	acyl-CoA dehydrogenase activity
EXW37_26770	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW37_26775	COG0183	Belongs to the thiolase family
EXW37_26780	COG2181	nitrate reductase activity
EXW37_26780	COG0247	lactate metabolic process
EXW37_26785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW37_26790	COG4294	response to UV
EXW37_26795	COG5001	Diguanylate cyclase
EXW37_26795	COG3300	MHYT domain
EXW37_26820	COG2197	response regulator
EXW37_26825	COG4585	Histidine kinase
EXW37_26830	COG0842	Transport permease protein
EXW37_26835	COG1131	(ABC) transporter
EXW37_26840	COG0024	Methionine aminopeptidase
EXW37_26850	COG2234	aminopeptidase activity
EXW37_26865	COG4506	Protein conserved in bacteria
EXW37_26870	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW37_26890	COG0010	Belongs to the arginase family
EXW37_26895	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW37_26900	COG2814	Major facilitator Superfamily
EXW37_26905	COG0789	Transcriptional regulator
EXW37_26910	COG0584	glycerophosphoryl diester phosphodiesterase
EXW37_26915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW37_26925	COG1994	Peptidase M50
EXW37_26935	COG1078	dGTPase activity
EXW37_26940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW37_26945	COG1120	ATPase activity
EXW37_26950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW37_26955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW37_26960	COG4844	belongs to the
EXW37_26980	COG0280	phosphate acetyltransferase
EXW37_26985	COG3253	May function as heme-dependent peroxidase
EXW37_26995	COG3773	Cell wall hydrolase
EXW37_27005	COG2363	Small membrane protein
EXW37_27020	COG2233	PERMEase
EXW37_27025	COG0561	phosphatase activity
EXW37_27030	COG2814	Major facilitator Superfamily
EXW37_27035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW37_27040	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW37_27045	COG1131	(ABC) transporter
EXW37_27050	COG2755	lipolytic protein G-D-S-L family
EXW37_27055	COG1609	Transcriptional regulator
EXW37_27065	COG0460	homoserine dehydrogenase
EXW37_27070	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW37_27075	COG2873	o-acetylhomoserine
EXW37_27090	COG2197	response regulator
EXW37_27095	COG4585	Histidine kinase
EXW37_27095	COG2203	Gaf domain
EXW37_27100	COG0351	phosphomethylpyrimidine kinase
EXW37_27105	COG3706	GGDEF domain
EXW37_27110	COG2879	small protein
EXW37_27115	COG1966	Carbon starvation protein
EXW37_27120	COG3279	Response regulator of the LytR AlgR family
EXW37_27125	COG0477	Major facilitator Superfamily
EXW37_27155	COG0840	transmembrane signaling receptor activity
EXW37_27165	COG1607	acyl-coa hydrolase
EXW37_27175	COG1216	Glycosyl transferase, family 2
EXW37_27180	COG0488	(ABC) transporter
EXW37_27195	COG0463	Glycosyl transferase, family 2
EXW37_27200	COG1309	transcriptional regulator
EXW37_27205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW37_27210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW37_27210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW37_27215	COG0628	permease
EXW37_27225	COG1380	Effector of murein hydrolase LrgA
EXW37_27230	COG3279	Response regulator of the LytR AlgR family
EXW37_27235	COG3275	phosphorelay sensor kinase activity
EXW37_27240	COG2814	Major facilitator Superfamily
EXW37_27245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW37_27250	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW37_27260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW37_27310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW37_27315	COG1272	protein, Hemolysin III
EXW37_27340	COG1164	Oligoendopeptidase f
EXW37_27350	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW37_27360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW37_27365	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW37_27370	COG4853	Protein conserved in bacteria
EXW37_27380	COG5002	protein histidine kinase activity
EXW37_27385	COG0745	RESPONSE REGULATOR receiver
EXW37_27415	COG0305	Participates in initiation and elongation during chromosome replication
EXW37_27420	COG0359	binds to the 23S rRNA
EXW37_27425	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW37_27430	COG4241	membrane
EXW37_27440	COG0629	single-stranded DNA binding
EXW37_27445	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW37_27450	COG0012	GTP binding
EXW37_27455	COG4481	Protein conserved in bacteria
EXW37_27460	COG0668	transmembrane transport
EXW37_27470	COG1475	DNA binding
EXW37_27475	COG1192	Involved in chromosome partitioning
EXW37_27480	COG1475	DNA binding
EXW37_27485	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW37_27490	COG0445	tRNA wobble uridine modification
EXW37_27495	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW37_27500	COG1847	R3H domain protein
EXW37_27505	COG0706	membrane insertase activity
EXW37_27510	COG0594	ribonuclease P activity
EXW37_27515	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW37_27575	COG1192	Involved in chromosome partitioning
EXW37_27595	COG0577	efflux transmembrane transporter activity
EXW37_27600	COG1136	(ABC) transporter
EXW37_27615	COG3402	PFAM membrane-flanked domain
EXW37_27700	COG1923	regulation of RNA biosynthetic process
EXW37_27715	COG2188	Transcriptional regulator
EXW37_27735	COG1674	ftsk spoiiie
EXW37_27795	COG0457	Tetratricopeptide repeat
EXW37_27830	COG1396	sequence-specific DNA binding
EXW37_27925	COG0791	NLP P60 protein
EXW37_27925	COG3883	PFAM NLP P60 protein
EXW37_28040	COG1780	Probably involved in ribonucleotide reductase function
EXW37_28060	COG0582	viral genome integration into host DNA
EXW37_28105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW37_28160	COG5002	protein histidine kinase activity
EXW37_28195	COG0778	Nitroreductase
EXW37_28220	COG0384	phenazine biosynthesis protein PhzF
EXW37_28225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EXW37_28245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW37_28260	COG1674	ftsk spoiiie
EXW37_28275	COG0741	lytic transglycosylase activity
EXW37_28280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW37_28415	COG0367	asparagine synthase
EXW37_28440	COG0463	Glycosyl transferase, family 2
EXW37_28445	COG0463	Glycosyl transferase, family 2
EXW37_28450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW37_28455	COG1086	Polysaccharide biosynthesis protein
EXW37_28460	COG1088	dTDP-glucose 4,6-dehydratase activity
EXW37_28465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW37_28470	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW37_28485	COG2089	acid synthase
EXW37_28490	COG4641	Protein conserved in bacteria
EXW37_28570	COG0745	RESPONSE REGULATOR receiver
EXW37_28575	COG2205	protein histidine kinase activity
EXW37_28590	COG1136	(ABC) transporter
EXW37_28595	COG0577	efflux transmembrane transporter activity
EXW37_28605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW37_28605	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW37_28630	COG1136	(ABC) transporter
EXW37_28695	COG1115	amino acid carrier protein
EXW37_28705	COG1114	Component of the transport system for branched-chain amino acids
EXW37_28710	COG3409	Peptidoglycan-binding domain 1 protein
EXW37_28710	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW37_28715	COG2239	Acts as a magnesium transporter
EXW37_28720	COG0772	Belongs to the SEDS family
EXW37_28730	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW37_28745	COG0697	spore germination
EXW37_28755	COG1252	NADH dehydrogenase
EXW37_28760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW37_28760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW37_28765	COG2002	toxin-antitoxin pair type II binding
EXW37_28775	COG1923	regulation of RNA biosynthetic process
EXW37_28830	COG2814	Major facilitator Superfamily
EXW37_28855	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW37_28865	COG2002	toxin-antitoxin pair type II binding
EXW37_28920	COG2031	fatty acid transporter
EXW37_28930	COG2312	Erythromycin esterase
EXW37_28960	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW37_28985	COG1388	LysM domain
EXW37_28985	COG3103	Sh3 type 3 domain protein
EXW37_28985	COG0791	NLP P60 protein
EXW37_29005	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW37_29020	COG0583	DNA-binding transcription factor activity
EXW37_29025	COG0768	penicillin binding
EXW37_29035	COG4990	cell redox homeostasis
EXW37_29040	COG0745	RESPONSE REGULATOR receiver
EXW37_29045	COG5002	protein histidine kinase activity
EXW37_29060	COG0745	RESPONSE REGULATOR receiver
EXW37_29090	COG0833	amino acid
EXW37_29095	COG1285	pathogenesis
EXW37_29105	COG2267	carboxylic ester hydrolase activity
EXW37_29120	COG0840	transmembrane signaling receptor activity
EXW37_29160	COG0083	homoserine kinase activity
EXW37_29190	COG4974	Belongs to the 'phage' integrase family
EXW37_29205	COG2333	competence protein COMEC
EXW37_29205	COG0658	competence protein
EXW37_29260	COG2423	ornithine cyclodeaminase activity
EXW37_29270	COG2175	clavaminate synthase activity
EXW37_29275	COG0137	argininosuccinate synthase activity
EXW37_29290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW37_29295	COG0251	oxidation-reduction process
EXW37_29305	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW37_29310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW37_29315	COG1960	acyl-CoA dehydrogenase activity
EXW37_29340	COG0556	nucleotide-excision repair
EXW37_29345	COG0039	L-malate dehydrogenase activity
EXW37_29365	COG0436	Aminotransferase
EXW37_29405	COG0492	ferredoxin-NADP+ reductase activity
EXW37_29420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW37_29420	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EXW37_29430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW37_29435	COG1960	acyl-CoA dehydrogenase activity
EXW37_29450	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW37_29460	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EXW37_29490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW37_29500	COG0438	transferase activity, transferring glycosyl groups
EXW37_29505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW37_29510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW37_29525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW37_29535	COG1131	(ABC) transporter
EXW37_29550	COG2378	regulation of single-species biofilm formation
EXW37_29590	COG2002	toxin-antitoxin pair type II binding
EXW37_29660	COG2814	Major facilitator Superfamily
EXW37_29665	COG0583	DNA-binding transcription factor activity
EXW37_29740	COG2357	RelA SpoT domain protein
EXW37_29745	COG2814	Major facilitator Superfamily
EXW37_29755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW37_29835	COG1725	Transcriptional regulator
EXW37_29840	COG1131	(ABC) transporter
EXW37_29880	COG1329	Transcriptional regulator
EXW37_29915	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW37_29920	COG4974	Belongs to the 'phage' integrase family
EXW37_29925	COG0024	Methionine aminopeptidase