locus-tag	class	description
EXW26_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW26_00010	COG0592	DNA-directed DNA polymerase activity
EXW26_00015	COG2501	S4 domain
EXW26_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW26_00025	COG0187	DNA topoisomerase II activity
EXW26_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW26_00065	COG0516	GMP reductase activity
EXW26_00065	COG0517	IMP dehydrogenase activity
EXW26_00070	COG1686	Belongs to the peptidase S11 family
EXW26_00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW26_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW26_00100	COG1428	Deoxynucleoside kinase
EXW26_00105	COG1428	Deoxynucleoside kinase
EXW26_00110	COG1335	isochorismatase
EXW26_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW26_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW26_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW26_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW26_00180	COG1982	Orn Lys Arg decarboxylase major
EXW26_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW26_00190	COG0470	DNA polymerase III
EXW26_00195	COG1774	PSP1 C-terminal conserved region
EXW26_00200	COG4467	Involved in initiation control of chromosome replication
EXW26_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW26_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW26_00220	COG2002	toxin-antitoxin pair type II binding
EXW26_00230	COG0084	hydrolase, TatD family'
EXW26_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW26_00250	COG4466	Protein conserved in bacteria
EXW26_00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW26_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW26_00270	COG0251	oxidation-reduction process
EXW26_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW26_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW26_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW26_00305	COG2002	toxin-antitoxin pair type II binding
EXW26_00310	COG2244	polysaccharide biosynthetic process
EXW26_00315	COG3956	TIGRFAM MazG family protein
EXW26_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW26_00340	COG1098	S1 RNA binding domain
EXW26_00355	COG2208	phosphoserine phosphatase activity
EXW26_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW26_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW26_00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW26_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW26_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW26_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW26_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW26_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW26_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW26_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW26_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW26_00420	COG1396	sequence-specific DNA binding
EXW26_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW26_00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW26_00520	COG3880	PFAM UvrB UvrC protein
EXW26_00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW26_00530	COG0542	response to heat
EXW26_00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW26_00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW26_00545	COG4956	integral membrane protein (PIN domain superfamily)
EXW26_00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW26_00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW26_00565	COG1045	serine acetyltransferase
EXW26_00570	COG0215	cysteine-tRNA ligase activity
EXW26_00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW26_00585	COG3688	RNA-binding protein containing a PIN domain
EXW26_00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW26_00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW26_00605	COG0250	Participates in transcription elongation, termination and antitermination
EXW26_00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW26_00615	COG0081	regulation of translation
EXW26_00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW26_00625	COG0222	ribosome binding
EXW26_00630	COG2813	Specifically methylates the guanine in position
EXW26_00635	COG0085	RNA polymerase activity
EXW26_00640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW26_00645	COG1358	cellular component organization or biogenesis
EXW26_00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW26_00660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW26_00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW26_00670	COG0051	transcription antitermination factor activity, RNA binding
EXW26_00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW26_00680	COG0088	Forms part of the polypeptide exit tunnel
EXW26_00685	COG0089	rRNA binding
EXW26_00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW26_00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW26_00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW26_00715	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW26_00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW26_00730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW26_00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW26_00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW26_00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW26_00765	COG1841	ribosomal large subunit assembly
EXW26_00770	COG0200	Binds to the 23S rRNA
EXW26_00775	COG0201	protein transport
EXW26_00780	COG0563	adenylate kinase activity
EXW26_00785	COG0024	Methionine aminopeptidase
EXW26_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW26_00800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW26_00805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW26_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW26_00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW26_00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW26_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW26_00860	COG0489	protein tyrosine kinase activity
EXW26_00870	COG2194	sulfuric ester hydrolase activity
EXW26_00875	COG0726	polysaccharide deacetylase
EXW26_00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW26_00960	COG4856	YbbR-like protein
EXW26_00965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW26_01010	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_01015	COG2011	ABC-type metal ion transport system permease component
EXW26_01025	COG1464	Belongs to the NlpA lipoprotein family
EXW26_01040	COG0277	FAD linked oxidase domain protein
EXW26_01045	COG2271	Major facilitator Superfamily
EXW26_01055	COG2814	Major facilitator Superfamily
EXW26_01075	COG0601	transmembrane transport
EXW26_01080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW26_01085	COG0444	Belongs to the ABC transporter superfamily
EXW26_01090	COG4608	Belongs to the ABC transporter superfamily
EXW26_01095	COG4166	transmembrane transport
EXW26_01105	COG2207	Transcriptional regulator
EXW26_01120	COG4166	transmembrane transport
EXW26_01125	COG4166	transmembrane transport
EXW26_01130	COG0656	L-ascorbic acid biosynthetic process
EXW26_01135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW26_01150	COG4149	molybdate abc transporter
EXW26_01155	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW26_01160	COG1910	domain protein
EXW26_01175	COG0697	spore germination
EXW26_01190	COG0204	Acyl-transferase
EXW26_01200	COG1609	Transcriptional regulator
EXW26_01210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_01230	COG5298	Protein conserved in bacteria
EXW26_01255	COG0488	(ABC) transporter
EXW26_01265	COG0747	negative chemotaxis
EXW26_01275	COG0601	transmembrane transport
EXW26_01280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW26_01285	COG0444	Belongs to the ABC transporter superfamily
EXW26_01290	COG4608	Belongs to the ABC transporter superfamily
EXW26_01295	COG0561	phosphatase activity
EXW26_01325	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW26_01330	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW26_01340	COG0531	amino acid
EXW26_01345	COG2814	Major facilitator Superfamily
EXW26_01355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW26_01365	COG4294	response to UV
EXW26_01370	COG0705	Rhomboid family
EXW26_01375	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW26_01380	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW26_01385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW26_01390	COG0864	Transcriptional regulator
EXW26_01395	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW26_01400	COG2183	response to ionizing radiation
EXW26_01500	COG0802	atpase or kinase
EXW26_01505	COG1214	PFAM Peptidase M22, glycoprotease
EXW26_01510	COG0456	acetyltransferase
EXW26_01520	COG0488	(ABC) transporter
EXW26_01525	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW26_01535	COG1266	CAAX protease self-immunity
EXW26_01540	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW26_01545	COG0459	protein refolding
EXW26_01550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW26_01550	COG0519	Catalyzes the synthesis of GMP from XMP
EXW26_01555	COG2252	PERMEase
EXW26_01565	COG5002	protein histidine kinase activity
EXW26_01590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW26_01615	COG0693	protein deglycase activity
EXW26_01670	COG2205	protein histidine kinase activity
EXW26_01695	COG0697	spore germination
EXW26_01720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW26_01725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW26_01730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW26_01735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW26_01740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW26_01745	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW26_01750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW26_01755	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW26_01760	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW26_01765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW26_01770	COG0138	bifunctional purine biosynthesis protein purh
EXW26_01775	COG0151	Belongs to the GarS family
EXW26_01800	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW26_01805	COG0210	DNA helicase
EXW26_01810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW26_01815	COG4851	CamS sex pheromone cAM373 precursor
EXW26_01825	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_01830	COG1335	isochorismatase
EXW26_01840	COG2011	ABC-type metal ion transport system permease component
EXW26_01845	COG1464	Belongs to the NlpA lipoprotein family
EXW26_01860	COG0003	Pfam Anion-transporting ATPase
EXW26_01865	COG1846	Transcriptional regulator
EXW26_01870	COG4682	membrane
EXW26_01880	COG0154	amidase activity
EXW26_01885	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW26_01890	COG1597	lipid kinase activity
EXW26_01895	COG0546	phosphoglycolate phosphatase activity
EXW26_01900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW26_01910	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_01915	COG2076	Multidrug Resistance protein
EXW26_01920	COG2309	aminopeptidase activity
EXW26_01935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_01945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW26_01950	COG5002	protein histidine kinase activity
EXW26_01955	COG4807	Protein conserved in bacteria
EXW26_01980	COG1757	Na H antiporter
EXW26_01985	COG1473	amidohydrolase
EXW26_02005	COG0450	alkyl hydroperoxide reductase
EXW26_02015	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW26_02025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_02030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_02035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_02040	COG0492	ferredoxin-NADP+ reductase activity
EXW26_02050	COG0166	Belongs to the GPI family
EXW26_02075	COG5002	protein histidine kinase activity
EXW26_02095	COG3541	Predicted nucleotidyltransferase
EXW26_02100	COG0723	plastoquinol--plastocyanin reductase activity
EXW26_02100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW26_02110	COG0765	amino acid transport
EXW26_02115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW26_02125	COG0840	transmembrane signaling receptor activity
EXW26_02150	COG0549	Belongs to the carbamate kinase family
EXW26_02165	COG0277	FAD linked oxidase domain protein
EXW26_02170	COG0366	Alpha amylase catalytic
EXW26_02175	COG2190	(PTS) system
EXW26_02175	COG1263	PTS System
EXW26_02175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW26_02195	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW26_02205	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW26_02225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW26_02230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW26_02235	COG1116	anion transmembrane transporter activity
EXW26_02240	COG0488	(ABC) transporter
EXW26_02290	COG2270	Major facilitator Superfamily
EXW26_02320	COG2310	stress, protein
EXW26_02325	COG2310	stress, protein
EXW26_02330	COG2310	stress, protein
EXW26_02335	COG0861	Integral membrane protein TerC family
EXW26_02345	COG3853	Toxic anion resistance protein (TelA)
EXW26_02355	COG4840	Belongs to the UPF0435 family
EXW26_02365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW26_02375	COG1295	ribonuclease BN
EXW26_02380	COG2217	Heavy metal translocating P-type atpase
EXW26_02385	COG0697	spore germination
EXW26_02410	COG0586	Pfam SNARE associated Golgi protein
EXW26_02425	COG3871	stress protein (general stress protein 26)
EXW26_02430	COG0387	Pfam Sodium calcium exchanger
EXW26_02440	COG0535	radical SAM domain protein
EXW26_02460	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW26_02480	COG3829	transcription factor binding
EXW26_02490	COG0833	amino acid
EXW26_02495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW26_02515	COG2066	Belongs to the glutaminase family
EXW26_02525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW26_02525	COG1263	PTS System
EXW26_02530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW26_02545	COG1216	Glycosyl transferase, family 2
EXW26_02555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW26_02555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW26_02560	COG0463	Glycosyl transferase, family 2
EXW26_02575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW26_02580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW26_02595	COG1228	amidohydrolase
EXW26_02600	COG1090	epimerase
EXW26_02605	COG2137	regulation of response to DNA damage stimulus
EXW26_02630	COG1988	membrane-bound metal-dependent
EXW26_02635	COG1194	a g-specific adenine glycosylase
EXW26_02655	COG3557	Belongs to the UPF0374 family
EXW26_02660	COG1132	(ABC) transporter
EXW26_02665	COG4129	membrane
EXW26_02675	COG0070	glutamate synthase
EXW26_02675	COG0067	glutamate synthase
EXW26_02675	COG0069	glutamate synthase activity
EXW26_02680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW26_02685	COG4555	ABC transporter
EXW26_02705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW26_02710	COG0735	belongs to the Fur family
EXW26_02835	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW26_02840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW26_02860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW26_02870	COG2766	serine protein kinase
EXW26_02875	COG2718	Belongs to the UPF0229 family
EXW26_02890	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW26_02895	COG2268	Band 7 protein
EXW26_02910	COG3290	protein histidine kinase activity
EXW26_02915	COG4565	transcriptional regulatory protein
EXW26_02920	COG2851	Citrate transporter
EXW26_02945	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW26_02950	COG3842	ATPase activity
EXW26_02955	COG1175	transmembrane transport
EXW26_02960	COG0395	ABC-type sugar transport system, permease component
EXW26_02970	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW26_02975	COG0745	RESPONSE REGULATOR receiver
EXW26_02980	COG5002	protein histidine kinase activity
EXW26_02990	COG4990	cell redox homeostasis
EXW26_03000	COG3290	protein histidine kinase activity
EXW26_03005	COG4565	transcriptional regulatory protein
EXW26_03010	COG3493	citrate carrier protein
EXW26_03015	COG0281	malic enzyme
EXW26_03025	COG0697	spore germination
EXW26_03030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_03040	COG5002	protein histidine kinase activity
EXW26_03045	COG0745	RESPONSE REGULATOR receiver
EXW26_03050	COG0456	acetyltransferase
EXW26_03055	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW26_03060	COG3383	formate dehydrogenase (NAD+) activity
EXW26_03065	COG2427	Protein of unknown function (DUF1641)
EXW26_03080	COG0531	amino acid
EXW26_03090	COG0640	Transcriptional regulator
EXW26_03095	COG2217	Heavy metal translocating P-type atpase
EXW26_03100	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW26_03110	COG3227	Zinc metalloprotease (Elastase)
EXW26_03130	COG2720	vancomycin resistance protein
EXW26_03135	COG1316	TRANSCRIPTIONal
EXW26_03140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_03145	COG0346	lactoylglutathione lyase activity
EXW26_03150	COG1253	flavin adenine dinucleotide binding
EXW26_03155	COG1027	Aspartate ammonia-lyase
EXW26_03160	COG1620	l-lactate permease
EXW26_03165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW26_03185	COG3104	oligopeptide transport
EXW26_03190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_03195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_03200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_03215	COG0156	8-amino-7-oxononanoate synthase activity
EXW26_03220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW26_03230	COG4548	von Willebrand factor, type A
EXW26_03235	COG0714	Associated with various cellular activities
EXW26_03255	COG0531	amino acid
EXW26_03260	COG2188	Transcriptional regulator
EXW26_03265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW26_03265	COG1263	PTS System
EXW26_03270	COG0366	Alpha amylase catalytic
EXW26_03285	COG0697	spore germination
EXW26_03290	COG4585	Histidine kinase
EXW26_03295	COG2197	response regulator
EXW26_03300	COG1404	Belongs to the peptidase S8 family
EXW26_03315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW26_03320	COG1115	amino acid carrier protein
EXW26_03330	COG1126	abc transporter atp-binding protein
EXW26_03335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW26_03340	COG0765	amino acid transport
EXW26_03345	COG0765	amino acid transport
EXW26_03350	COG0833	amino acid
EXW26_03375	COG2378	regulation of single-species biofilm formation
EXW26_03380	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW26_03385	COG5002	protein histidine kinase activity
EXW26_03400	COG0659	secondary active sulfate transmembrane transporter activity
EXW26_03425	COG0601	transmembrane transport
EXW26_03430	COG4608	Belongs to the ABC transporter superfamily
EXW26_03440	COG2271	Major facilitator Superfamily
EXW26_03445	COG1846	Transcriptional regulator
EXW26_03450	COG0477	Major facilitator Superfamily
EXW26_03455	COG1609	Transcriptional regulator
EXW26_03460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW26_03465	COG1869	D-ribose catabolic process
EXW26_03475	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW26_03480	COG1879	ABC-type sugar transport system periplasmic component
EXW26_03510	COG1063	alcohol dehydrogenase
EXW26_03555	COG0840	transmembrane signaling receptor activity
EXW26_03560	COG3584	3D domain protein
EXW26_03560	COG3583	domain protein
EXW26_03565	COG1476	TRANSCRIPTIONal
EXW26_03585	COG3104	oligopeptide transport
EXW26_03590	COG1114	Component of the transport system for branched-chain amino acids
EXW26_03605	COG1113	amino acid transport
EXW26_03610	COG2252	PERMEase
EXW26_03615	COG3620	sequence-specific DNA binding
EXW26_03635	COG0475	glutathione-regulated potassium exporter activity
EXW26_03635	COG0569	domain protein
EXW26_03650	COG1845	cytochrome c oxidase, subunit III
EXW26_03655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW26_03665	COG0833	amino acid
EXW26_03670	COG4990	cell redox homeostasis
EXW26_03685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW26_03690	COG0697	spore germination
EXW26_03695	COG0531	amino acid
EXW26_03705	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW26_03710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW26_03720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW26_03725	COG0573	inorganic phosphate transmembrane transporter activity
EXW26_03730	COG0581	inorganic phosphate transmembrane transporter activity
EXW26_03740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW26_03860	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW26_03880	COG3103	Sh3 type 3 domain protein
EXW26_03880	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW26_03880	COG4991	sh3 domain protein
EXW26_03885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW26_03890	COG1116	anion transmembrane transporter activity
EXW26_03895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW26_03900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW26_03905	COG0352	thiamine-phosphate diphosphorylase activity
EXW26_03910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW26_03915	COG2104	thiamine diphosphate biosynthetic process
EXW26_03920	COG2022	thiamine diphosphate biosynthetic process
EXW26_03925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW26_03930	COG0351	phosphomethylpyrimidine kinase
EXW26_03955	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW26_03960	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW26_03965	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW26_03970	COG2205	protein histidine kinase activity
EXW26_03975	COG2814	Major facilitator Superfamily
EXW26_03980	COG1846	Transcriptional regulator
EXW26_04000	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW26_04005	COG1129	ABC transporter
EXW26_04010	COG1879	ABC-type sugar transport system periplasmic component
EXW26_04015	COG2252	PERMEase
EXW26_04020	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_04085	COG0778	Nitroreductase
EXW26_04090	COG2719	SpoVR family
EXW26_04115	COG1937	Protein conserved in bacteria
EXW26_04120	COG0425	Belongs to the sulfur carrier protein TusA family
EXW26_04120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_04125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_04125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_04130	COG0425	Belongs to the sulfur carrier protein TusA family
EXW26_04135	COG0425	Belongs to the sulfur carrier protein TusA family
EXW26_04135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_04140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_04145	COG2210	Belongs to the sulfur carrier protein TusA family
EXW26_04150	COG0730	response to heat
EXW26_04160	COG1316	TRANSCRIPTIONal
EXW26_04180	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW26_04185	COG0604	alcohol dehydrogenase
EXW26_04190	COG2814	Major facilitator Superfamily
EXW26_04205	COG3711	transcriptional antiterminator
EXW26_04205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW26_04210	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW26_04215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW26_04240	COG1388	LysM domain
EXW26_04240	COG3584	3D domain protein
EXW26_04245	COG0577	efflux transmembrane transporter activity
EXW26_04250	COG1136	(ABC) transporter
EXW26_04260	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW26_04275	COG1114	Component of the transport system for branched-chain amino acids
EXW26_04280	COG3546	catalase activity
EXW26_04310	COG0586	Pfam SNARE associated Golgi protein
EXW26_04340	COG0531	amino acid
EXW26_04345	COG0475	glutathione-regulated potassium exporter activity
EXW26_04355	COG1737	Transcriptional regulator
EXW26_04365	COG1263	PTS System
EXW26_04365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW26_04375	COG2259	Doxx family
EXW26_04400	COG1522	sequence-specific DNA binding
EXW26_04425	COG2076	Multidrug Resistance protein
EXW26_04430	COG1309	transcriptional regulator
EXW26_04435	COG2814	Major facilitator Superfamily
EXW26_04440	COG1733	regulation of RNA biosynthetic process
EXW26_04455	COG4533	DNA binding
EXW26_04460	COG2211	Major facilitator Superfamily
EXW26_04480	COG0531	amino acid
EXW26_04485	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_04500	COG1132	(ABC) transporter
EXW26_04505	COG1132	(ABC) transporter
EXW26_04510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW26_04515	COG0765	amino acid transport
EXW26_04520	COG1126	abc transporter atp-binding protein
EXW26_04535	COG0189	ligase activity
EXW26_04545	COG4399	Belongs to the UPF0754 family
EXW26_04550	COG3679	Belongs to the UPF0342 family
EXW26_04565	COG0028	Belongs to the TPP enzyme family
EXW26_04570	COG3527	Alpha-acetolactate decarboxylase
EXW26_04575	COG0463	Glycosyl transferase, family 2
EXW26_04580	COG1216	Glycosyl transferase, family 2
EXW26_04585	COG2094	Belongs to the DNA glycosylase MPG family
EXW26_04590	COG0561	phosphatase activity
EXW26_04600	COG3409	Peptidoglycan-binding domain 1 protein
EXW26_04600	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW26_04605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW26_04610	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_04620	COG0659	secondary active sulfate transmembrane transporter activity
EXW26_04625	COG2244	polysaccharide biosynthetic process
EXW26_04645	COG1024	Enoyl-CoA hydratase
EXW26_04675	COG1363	Peptidase, m42
EXW26_04690	COG2318	DinB family
EXW26_04710	COG0579	oxidoreductase
EXW26_04725	COG2197	response regulator
EXW26_04750	COG0601	transmembrane transport
EXW26_04755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW26_04760	COG0444	Belongs to the ABC transporter superfamily
EXW26_04765	COG4608	Belongs to the ABC transporter superfamily
EXW26_04790	COG0477	Major facilitator Superfamily
EXW26_04795	COG3290	protein histidine kinase activity
EXW26_04800	COG4565	transcriptional regulatory protein
EXW26_04805	COG3181	Tripartite tricarboxylate transporter family receptor
EXW26_04850	COG4978	Transcriptional regulator
EXW26_04850	COG0789	Transcriptional regulator
EXW26_04865	COG0305	Participates in initiation and elongation during chromosome replication
EXW26_04900	COG1842	Phage shock protein A
EXW26_04910	COG0477	Major facilitator Superfamily
EXW26_04970	COG2814	Major facilitator Superfamily
EXW26_04975	COG0640	Transcriptional regulator
EXW26_05000	COG2376	Dihydroxyacetone kinase
EXW26_05020	COG2376	Dihydroxyacetone kinase
EXW26_05035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW26_05040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW26_05080	COG1959	2 iron, 2 sulfur cluster binding
EXW26_05100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW26_05115	COG0457	Tetratricopeptide repeat
EXW26_05125	COG2373	Large extracellular alpha-helical protein
EXW26_05180	COG0825	malonyl-CoA metabolic process
EXW26_05205	COG2807	transmembrane transport
EXW26_05210	COG2186	Transcriptional regulator
EXW26_05225	COG4585	Histidine kinase
EXW26_05230	COG2197	response regulator
EXW26_05260	COG0420	3'-5' exonuclease activity
EXW26_05265	COG4717	serine-type aminopeptidase activity
EXW26_05270	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW26_05280	COG0346	lactoylglutathione lyase activity
EXW26_05285	COG0346	lactoylglutathione lyase activity
EXW26_05290	COG0457	Tetratricopeptide repeat
EXW26_05300	COG2267	carboxylic ester hydrolase activity
EXW26_05310	COG3620	sequence-specific DNA binding
EXW26_05315	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW26_05320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW26_05325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW26_05330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW26_05335	COG1695	Transcriptional regulator
EXW26_05355	COG1595	DNA-templated transcription, initiation
EXW26_05370	COG3973	AAA domain
EXW26_05375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW26_05400	COG0537	adenosine 5'-monophosphoramidase activity
EXW26_05405	COG1131	(ABC) transporter
EXW26_05410	COG4473	ABC transporter
EXW26_05420	COG0247	lactate metabolic process
EXW26_05425	COG1139	Iron-sulfur cluster binding protein
EXW26_05430	COG1556	Lactate utilization protein
EXW26_05450	COG3402	PFAM membrane-flanked domain
EXW26_05455	COG3428	Bacterial PH domain
EXW26_05495	COG3402	PFAM membrane-flanked domain
EXW26_05500	COG3428	Bacterial PH domain
EXW26_05505	COG2329	Antibiotic biosynthesis monooxygenase
EXW26_05510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW26_05515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW26_05520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW26_05525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW26_05545	COG1309	transcriptional regulator
EXW26_05550	COG1511	domain protein
EXW26_05585	COG1609	Transcriptional regulator
EXW26_05595	COG1234	tRNA 3'-trailer cleavage
EXW26_05600	COG0095	Lipoate-protein ligase
EXW26_05610	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_05625	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW26_05635	COG4208	sulfate ABC transporter
EXW26_05650	COG1408	metallophosphoesterase
EXW26_05655	COG1078	dGTPase activity
EXW26_05670	COG1595	DNA-templated transcription, initiation
EXW26_05680	COG3708	Transcriptional regulator
EXW26_05680	COG2207	Transcriptional regulator
EXW26_05685	COG2205	protein histidine kinase activity
EXW26_05690	COG0745	RESPONSE REGULATOR receiver
EXW26_05710	COG0501	Belongs to the peptidase M48B family
EXW26_05715	COG0840	transmembrane signaling receptor activity
EXW26_05720	COG0697	spore germination
EXW26_05725	COG3693	PFAM glycoside hydrolase, family 10
EXW26_05730	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW26_05735	COG2224	Isocitrate lyase
EXW26_05745	COG1278	Cold shock
EXW26_05765	COG4903	ComK protein
EXW26_05770	COG0398	Pfam SNARE associated Golgi protein
EXW26_05780	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW26_05785	COG1074	ATP-dependent DNA helicase activity
EXW26_05835	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW26_05860	COG0367	asparagine synthase
EXW26_05880	COG0753	catalase activity
EXW26_05885	COG0004	ammonium transporteR
EXW26_05895	COG1666	GTP binding
EXW26_05900	COG2996	Protein conserved in bacteria
EXW26_05915	COG1329	Transcriptional regulator
EXW26_05950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW26_05960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_05975	COG0561	phosphatase activity
EXW26_05995	COG2267	carboxylic ester hydrolase activity
EXW26_06010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_06015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW26_06020	COG5504	Zn-dependent protease
EXW26_06040	COG0180	Tryptophanyl-tRNA synthetase
EXW26_06055	COG4166	transmembrane transport
EXW26_06060	COG0601	transmembrane transport
EXW26_06065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW26_06070	COG0444	Belongs to the ABC transporter superfamily
EXW26_06075	COG4608	Belongs to the ABC transporter superfamily
EXW26_06080	COG0534	Mate efflux family protein
EXW26_06085	COG4166	transmembrane transport
EXW26_06105	COG0861	Integral membrane protein TerC family
EXW26_06110	COG4862	establishment of competence for transformation
EXW26_06115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW26_06125	COG1164	Oligoendopeptidase f
EXW26_06135	COG2346	COG2346, Truncated hemoglobins
EXW26_06140	COG4116	CYTH
EXW26_06150	COG2357	RelA SpoT domain protein
EXW26_06160	COG0564	pseudouridine synthase activity
EXW26_06175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW26_06180	COG0772	Belongs to the SEDS family
EXW26_06185	COG1216	Glycosyl transferase, family 2
EXW26_06205	COG0463	Glycosyl transferase, family 2
EXW26_06205	COG0457	Tetratricopeptide repeat
EXW26_06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW26_06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW26_06285	COG2153	protein acetylation
EXW26_06290	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW26_06295	COG2382	esterase
EXW26_06320	COG5492	domain, Protein
EXW26_06325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW26_06340	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW26_06340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW26_06345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW26_06350	COG0134	indole-3-glycerol-phosphate synthase activity
EXW26_06355	COG0135	phosphoribosylanthranilate isomerase activity
EXW26_06360	COG0133	tryptophan synthase activity
EXW26_06365	COG0159	tryptophan synthase activity
EXW26_06375	COG1620	l-lactate permease
EXW26_06380	COG5634	Uncharacterized conserved protein (DUF2278)
EXW26_06440	COG2226	methyltransferase
EXW26_06460	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW26_06465	COG0567	Dehydrogenase, E1 component
EXW26_06470	COG1476	TRANSCRIPTIONal
EXW26_06495	COG4152	abc transporter atp-binding protein
EXW26_06500	COG1668	transmembrane transport
EXW26_06540	COG0582	viral genome integration into host DNA
EXW26_06580	COG1686	Belongs to the peptidase S11 family
EXW26_06585	COG0681	Belongs to the peptidase S26 family
EXW26_06620	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_06630	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW26_06635	COG1177	transmembrane transport
EXW26_06640	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW26_06650	COG2409	Drug exporters of the RND superfamily
EXW26_06660	COG0564	pseudouridine synthase activity
EXW26_06670	COG2340	Cysteine-rich secretory protein family
EXW26_06675	COG0247	lactate metabolic process
EXW26_06680	COG0277	FAD linked oxidase domain protein
EXW26_06685	COG3835	regulator
EXW26_06695	COG0745	RESPONSE REGULATOR receiver
EXW26_06700	COG5002	protein histidine kinase activity
EXW26_06705	COG2186	Transcriptional regulator
EXW26_06710	COG0247	lactate metabolic process
EXW26_06715	COG1139	Iron-sulfur cluster binding protein
EXW26_06720	COG1556	Lactate utilization protein
EXW26_06725	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW26_06735	COG2116	formate transmembrane transporter activity
EXW26_06740	COG0861	Integral membrane protein TerC family
EXW26_06745	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW26_06755	COG2030	dehydratase
EXW26_06775	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_06780	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW26_06790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW26_06805	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW26_06810	COG3842	ATPase activity
EXW26_06825	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW26_06835	COG1349	DNA-binding transcription factor activity
EXW26_06845	COG0235	Class ii aldolase
EXW26_06855	COG2861	carbohydrate metabolic process
EXW26_06865	COG3852	Histidine kinase
EXW26_06870	COG1846	Transcriptional regulator
EXW26_06880	COG2318	DinB family
EXW26_06885	COG5002	protein histidine kinase activity
EXW26_06890	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW26_06895	COG0720	synthase
EXW26_06905	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW26_06910	COG4873	Protein conserved in bacteria
EXW26_06920	COG0456	acetyltransferase
EXW26_06940	COG1780	Probably involved in ribonucleotide reductase function
EXW26_06955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW26_06960	COG0531	amino acid
EXW26_06965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW26_06980	COG2204	response regulator
EXW26_06985	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_06995	COG1725	Transcriptional regulator
EXW26_07000	COG1131	(ABC) transporter
EXW26_07010	COG1131	(ABC) transporter
EXW26_07015	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW26_07020	COG1266	CAAX protease self-immunity
EXW26_07030	COG1522	sequence-specific DNA binding
EXW26_07040	COG1335	isochorismatase
EXW26_07050	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW26_07055	COG2070	2-Nitropropane dioxygenase
EXW26_07060	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW26_07065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW26_07070	COG1696	Membrane protein involved in D-alanine export
EXW26_07075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW26_07090	COG0716	FMN binding
EXW26_07115	COG0534	Mate efflux family protein
EXW26_07140	COG1846	Transcriptional regulator
EXW26_07150	COG1301	dicarboxylic acid transport
EXW26_07155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW26_07165	COG3874	Sporulation protein YtfJ
EXW26_07185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW26_07190	COG0028	Belongs to the TPP enzyme family
EXW26_07195	COG0440	acetolactate synthase activity
EXW26_07205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW26_07215	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW26_07225	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW26_07230	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW26_07240	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW26_07245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW26_07250	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW26_07255	COG0107	imidazoleglycerol-phosphate synthase activity
EXW26_07265	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW26_07270	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW26_07285	COG1183	phosphatidylcholine synthase activity
EXW26_07290	COG1368	sulfuric ester hydrolase activity
EXW26_07300	COG0019	diaminopimelate decarboxylase activity
EXW26_07310	COG0175	sulfate reduction
EXW26_07315	COG2046	Belongs to the sulfate adenylyltransferase family
EXW26_07320	COG0529	Catalyzes the synthesis of activated sulfate
EXW26_07325	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW26_07345	COG1648	precorrin-2 dehydrogenase activity
EXW26_07350	COG0733	neurotransmitter:sodium symporter activity
EXW26_07370	COG1757	Na H antiporter
EXW26_07390	COG4758	membrane
EXW26_07395	COG4585	Histidine kinase
EXW26_07400	COG2197	response regulator
EXW26_07410	COG1114	Component of the transport system for branched-chain amino acids
EXW26_07420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW26_07465	COG0730	response to heat
EXW26_07470	COG0306	phosphate transporter
EXW26_07475	COG1392	Phosphate transport regulator
EXW26_07480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW26_07495	COG3852	Histidine kinase
EXW26_07500	COG1801	Protein of unknown function DUF72
EXW26_07510	COG0582	viral genome integration into host DNA
EXW26_07515	COG5002	protein histidine kinase activity
EXW26_07530	COG0392	lysyltransferase activity
EXW26_07530	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW26_07545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW26_07550	COG1686	Belongs to the peptidase S11 family
EXW26_07555	COG2715	membrane protein required for spore maturation
EXW26_07560	COG0700	Nucleoside recognition
EXW26_07565	COG1187	pseudouridine synthase activity
EXW26_07575	COG1333	cytochrome c biogenesis protein
EXW26_07580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW26_07585	COG0745	RESPONSE REGULATOR receiver
EXW26_07590	COG5002	protein histidine kinase activity
EXW26_07595	COG2096	Adenosyltransferase
EXW26_07600	COG4942	peptidase
EXW26_07610	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW26_07615	COG1141	Ferredoxin
EXW26_07625	COG4955	Helix-turn-helix domain
EXW26_07630	COG0514	ATP-dependent DNA helicase (RecQ)
EXW26_07635	COG1266	CAAX protease self-immunity
EXW26_07645	COG1408	metallophosphoesterase
EXW26_07660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW26_07680	COG0492	ferredoxin-NADP+ reductase activity
EXW26_07685	COG0252	asparaginase activity
EXW26_07690	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW26_07700	COG1304	FMN binding
EXW26_07730	COG1160	GTP binding
EXW26_07735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW26_07755	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW26_07765	COG0302	gtp cyclohydrolase
EXW26_07770	COG0142	geranyltranstransferase activity
EXW26_07775	COG2226	methyltransferase
EXW26_07780	COG0142	geranyltranstransferase activity
EXW26_07795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW26_07805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW26_07810	COG0457	Tetratricopeptide repeat
EXW26_07815	COG5582	Belongs to the UPF0302 family
EXW26_07830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW26_07845	COG4347	Protein of unknown function (DUF1405)
EXW26_07860	COG2738	Putative neutral zinc metallopeptidase
EXW26_07870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_07875	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW26_07880	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW26_07885	COG1803	Methylglyoxal synthase
EXW26_07890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW26_07895	COG0438	transferase activity, transferring glycosyl groups
EXW26_07900	COG0617	tRNA 3'-terminal CCA addition
EXW26_07910	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW26_07915	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW26_07925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW26_07925	COG1199	ATP-dependent helicase activity
EXW26_07945	COG3935	DnaD domain protein
EXW26_07950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW26_07960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW26_07960	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW26_07965	COG3331	DNA recombination
EXW26_08000	COG4474	Belongs to the UPF0398 family
EXW26_08005	COG3599	regulation of cell shape
EXW26_08015	COG0116	Belongs to the methyltransferase superfamily
EXW26_08020	COG4974	Belongs to the 'phage' integrase family
EXW26_08110	COG1199	ATP-dependent helicase activity
EXW26_08115	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW26_08125	COG0024	Methionine aminopeptidase
EXW26_08135	COG2233	PERMEase
EXW26_08140	COG2311	Membrane
EXW26_08150	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW26_08160	COG0456	acetyltransferase
EXW26_08210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW26_08225	COG0454	-acetyltransferase
EXW26_08245	COG0328	RNA-DNA hybrid ribonuclease activity
EXW26_08280	COG3403	YqcI/YcgG family
EXW26_08285	COG1280	lysine exporter protein (LysE YggA)
EXW26_08300	COG3162	membrane
EXW26_08305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW26_08310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW26_08320	COG0475	glutathione-regulated potassium exporter activity
EXW26_08325	COG4978	Transcriptional regulator
EXW26_08325	COG0789	Transcriptional regulator
EXW26_08330	COG0534	Mate efflux family protein
EXW26_08335	COG2323	membrane
EXW26_08340	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW26_08365	COG2814	Major facilitator Superfamily
EXW26_08385	COG1923	regulation of RNA biosynthetic process
EXW26_08395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW26_08400	COG1360	Flagellar Motor Protein
EXW26_08405	COG2201	protein-glutamate methylesterase activity
EXW26_08410	COG0643	Histidine kinase
EXW26_08410	COG2198	Histidine kinase
EXW26_08415	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW26_08415	COG1776	CheC inhibitor of MCP methylation
EXW26_08430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW26_08450	COG1256	bacterial-type flagellum assembly
EXW26_08455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW26_08475	COG1815	bacterial-type flagellum-dependent cell motility
EXW26_08480	COG1558	bacterial-type flagellum-dependent cell motility
EXW26_08490	COG1766	The M ring may be actively involved in energy transduction
EXW26_08495	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW26_08505	COG1157	protein secretion by the type III secretion system
EXW26_08525	COG1749	Flagellar hook protein flgE
EXW26_08540	COG0784	Response regulator, receiver
EXW26_08540	COG0835	chemotaxis
EXW26_08565	COG0861	Integral membrane protein TerC family
EXW26_08575	COG3383	formate dehydrogenase (NAD+) activity
EXW26_08580	COG2427	Protein of unknown function (DUF1641)
EXW26_08585	COG5609	conserved protein (DUF2294)
EXW26_08590	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW26_08600	COG2116	formate transmembrane transporter activity
EXW26_08605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW26_08610	COG0303	'Molybdopterin
EXW26_08615	COG0314	molybdopterin synthase activity
EXW26_08620	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW26_08630	COG0489	protein tyrosine kinase activity
EXW26_08635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW26_08640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW26_08645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW26_08650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW26_08655	COG0741	lytic transglycosylase activity
EXW26_08665	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW26_08670	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW26_08670	COG1776	CheC inhibitor of MCP methylation
EXW26_08680	COG1338	Plays a role in the flagellum-specific transport system
EXW26_08685	COG1987	bacterial-type flagellum assembly
EXW26_08695	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW26_08700	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW26_08705	COG1419	protein localization to endoplasmic reticulum
EXW26_08710	COG4786	Flagellar basal body rod
EXW26_08715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW26_08755	COG2329	Antibiotic biosynthesis monooxygenase
EXW26_08770	COG2814	Major facilitator Superfamily
EXW26_08780	COG0583	DNA-binding transcription factor activity
EXW26_08785	COG3842	ATPase activity
EXW26_08835	COG0406	alpha-ribazole phosphatase activity
EXW26_08865	COG0367	asparagine synthase
EXW26_08895	COG1802	Transcriptional regulator
EXW26_08900	COG0697	spore germination
EXW26_08905	COG0438	transferase activity, transferring glycosyl groups
EXW26_08905	COG1216	Glycosyl transferase, family 2
EXW26_08910	COG1757	Na H antiporter
EXW26_08935	COG0534	Mate efflux family protein
EXW26_08940	COG3340	Belongs to the peptidase S51 family
EXW26_08960	COG0785	Cytochrome C biogenesis protein
EXW26_08965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW26_08980	COG3048	D-serine ammonia-lyase activity
EXW26_08985	COG2733	membrane
EXW26_09015	COG2197	response regulator
EXW26_09025	COG1131	(ABC) transporter
EXW26_09045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW26_09050	COG0528	UMP kinase activity
EXW26_09060	COG1027	Aspartate ammonia-lyase
EXW26_09065	COG0281	malic enzyme
EXW26_09070	COG4191	Histidine kinase
EXW26_09075	COG0784	Response regulator, receiver
EXW26_09080	COG1846	Transcriptional regulator
EXW26_09090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW26_09105	COG2502	aspartate--ammonia ligase
EXW26_09110	COG3620	sequence-specific DNA binding
EXW26_09175	COG1695	Transcriptional regulator
EXW26_09190	COG0477	Major facilitator Superfamily
EXW26_09200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_09210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW26_09215	COG2223	nitrite transmembrane transporter activity
EXW26_09220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW26_09235	COG2244	polysaccharide biosynthetic process
EXW26_09240	COG0733	neurotransmitter:sodium symporter activity
EXW26_09250	COG5566	PFAM Mor transcription activator
EXW26_09255	COG2323	membrane
EXW26_09275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW26_09280	COG2132	Multicopper oxidase
EXW26_09290	COG5002	protein histidine kinase activity
EXW26_09295	COG0745	RESPONSE REGULATOR receiver
EXW26_09305	COG0129	dihydroxy-acid dehydratase activity
EXW26_09310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW26_09335	COG2814	Major facilitator Superfamily
EXW26_09340	COG3384	dioxygenase
EXW26_09375	COG1073	alpha beta
EXW26_09380	COG4166	transmembrane transport
EXW26_09385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_09390	COG0745	RESPONSE REGULATOR receiver
EXW26_09405	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW26_09410	COG1054	Belongs to the UPF0176 family
EXW26_09420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW26_09425	COG0531	amino acid
EXW26_09460	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW26_09475	COG4257	antibiotic catabolic process
EXW26_09480	COG2390	Transcriptional regulator
EXW26_09490	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW26_09495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_09500	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW26_09515	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW26_09530	COG0583	DNA-binding transcription factor activity
EXW26_09545	COG0006	proline dipeptidase activity
EXW26_09550	COG2132	Multicopper oxidase
EXW26_09565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW26_09585	COG1114	Component of the transport system for branched-chain amino acids
EXW26_09595	COG1276	copper resistance
EXW26_09595	COG2372	response to copper ion
EXW26_09600	COG4549	nuclear export factor GLE1
EXW26_09610	COG0697	spore germination
EXW26_09615	COG0583	DNA-binding transcription factor activity
EXW26_09620	COG1959	2 iron, 2 sulfur cluster binding
EXW26_09625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW26_09630	COG0778	Nitroreductase
EXW26_09640	COG0628	permease
EXW26_09655	COG1231	oxidoreductase activity
EXW26_09660	COG0523	cobalamin synthesis protein
EXW26_09670	COG0411	ABC transporter
EXW26_09690	COG0583	DNA-binding transcription factor activity
EXW26_09700	COG1942	4-Oxalocrotonate Tautomerase
EXW26_09715	COG0346	lactoylglutathione lyase activity
EXW26_09725	COG1271	oxidase subunit
EXW26_09730	COG1294	oxidase, subunit
EXW26_09735	COG4988	ABC transporter
EXW26_09740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW26_09765	COG1686	Belongs to the peptidase S11 family
EXW26_09780	COG1388	LysM domain
EXW26_09780	COG0791	NLP P60 protein
EXW26_09790	COG1132	(ABC) transporter
EXW26_09795	COG0745	RESPONSE REGULATOR receiver
EXW26_09800	COG5002	protein histidine kinase activity
EXW26_09805	COG0300	oxidoreductase activity
EXW26_09810	COG4122	O-methyltransferase activity
EXW26_09830	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EXW26_09840	COG0460	homoserine dehydrogenase
EXW26_09850	COG0083	homoserine kinase activity
EXW26_09865	COG1316	TRANSCRIPTIONal
EXW26_09880	COG1285	pathogenesis
EXW26_09885	COG1247	-acetyltransferase
EXW26_09905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW26_09915	COG1082	Xylose isomerase domain protein TIM barrel
EXW26_09925	COG2814	Major facilitator Superfamily
EXW26_09930	COG1279	arginine transmembrane transporter activity
EXW26_09935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_09945	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW26_09975	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW26_09980	COG0577	efflux transmembrane transporter activity
EXW26_09985	COG2002	toxin-antitoxin pair type II binding
EXW26_09990	COG1404	Belongs to the peptidase S8 family
EXW26_09995	COG0640	Transcriptional regulator
EXW26_10000	COG0667	Aldo Keto reductase
EXW26_10045	COG3949	Membrane
EXW26_10050	COG0783	Belongs to the Dps family
EXW26_10065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW26_10075	COG1231	oxidoreductase activity
EXW26_10080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_10085	COG4989	oxidoreductase activity
EXW26_10090	COG0523	cobalamin synthesis protein
EXW26_10095	COG0456	acetyltransferase
EXW26_10100	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW26_10125	COG1136	(ABC) transporter
EXW26_10130	COG0577	efflux transmembrane transporter activity
EXW26_10135	COG0745	RESPONSE REGULATOR receiver
EXW26_10140	COG2205	protein histidine kinase activity
EXW26_10145	COG1902	pentaerythritol trinitrate reductase activity
EXW26_10150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW26_10160	COG4166	transmembrane transport
EXW26_10165	COG0346	lactoylglutathione lyase activity
EXW26_10175	COG0406	alpha-ribazole phosphatase activity
EXW26_10185	COG5337	Spore coat protein CotH
EXW26_10190	COG1051	belongs to the nudix hydrolase family
EXW26_10195	COG0586	Pfam SNARE associated Golgi protein
EXW26_10200	COG2244	polysaccharide biosynthetic process
EXW26_10210	COG0701	Predicted permease
EXW26_10215	COG3689	TIGRFAM TIGR03943 family protein
EXW26_10220	COG1607	acyl-coa hydrolase
EXW26_10230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW26_10245	COG0702	epimerase
EXW26_10250	COG2839	Protein conserved in bacteria
EXW26_10255	COG1253	flavin adenine dinucleotide binding
EXW26_10280	COG1114	Component of the transport system for branched-chain amino acids
EXW26_10285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW26_10305	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW26_10320	COG1876	peptidase activity
EXW26_10325	COG0494	nUDIX hydrolase
EXW26_10335	COG2211	Major facilitator Superfamily
EXW26_10350	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW26_10360	COG0561	phosphatase activity
EXW26_10365	COG1846	Transcriptional regulator
EXW26_10370	COG2814	Major facilitator Superfamily
EXW26_10380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW26_10385	COG4106	trans-aconitate 2-methyltransferase activity
EXW26_10400	COG1819	glycosyl
EXW26_10405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_10410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_10435	COG0456	acetyltransferase
EXW26_10455	COG3874	Sporulation protein YtfJ
EXW26_10480	COG2226	methyltransferase
EXW26_10510	COG0604	alcohol dehydrogenase
EXW26_10515	COG1595	DNA-templated transcription, initiation
EXW26_10540	COG0426	domain, Protein
EXW26_10540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW26_10550	COG0386	Belongs to the glutathione peroxidase family
EXW26_10555	COG1305	Transglutaminase-like
EXW26_10560	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW26_10565	COG0714	Associated with various cellular activities
EXW26_10570	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW26_10575	COG1140	nitrate reductase beta subunit
EXW26_10580	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW26_10585	COG2181	nitrate reductase activity
EXW26_10590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW26_10595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW26_10600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW26_10605	COG0303	'Molybdopterin
EXW26_10610	COG0314	molybdopterin synthase activity
EXW26_10620	COG2223	nitrite transmembrane transporter activity
EXW26_10640	COG1648	precorrin-2 dehydrogenase activity
EXW26_10650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW26_10650	COG1587	Uroporphyrinogen-III synthase
EXW26_10655	COG2146	nitrite reductase [NAD(P)H] activity
EXW26_10660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW26_10665	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW26_10695	COG2359	stage V sporulation protein S
EXW26_10705	COG2856	Zn peptidase
EXW26_10725	COG1396	sequence-specific DNA binding
EXW26_10800	COG0582	viral genome integration into host DNA
EXW26_10805	COG1476	TRANSCRIPTIONal
EXW26_10835	COG0582	viral genome integration into host DNA
EXW26_10855	COG5484	DNA packaging
EXW26_10860	COG1783	phage Terminase large subunit
EXW26_10875	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EXW26_10880	COG4653	Phage capsid family
EXW26_11015	COG1418	mRNA catabolic process
EXW26_11020	COG0488	(ABC) transporter
EXW26_11040	COG1413	lyase activity
EXW26_11055	COG2521	methyltransferase
EXW26_11055	COG2136	Putative SAM-dependent methyltransferase
EXW26_11060	COG0018	arginyl-trna synthetase
EXW26_11115	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW26_11125	COG0017	Asparaginyl-tRNA synthetase
EXW26_11130	COG0733	neurotransmitter:sodium symporter activity
EXW26_11160	COG2610	gluconate transmembrane transporter activity
EXW26_11170	COG1794	racemase activity, acting on amino acids and derivatives
EXW26_11180	COG0456	acetyltransferase
EXW26_11185	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW26_11190	COG1131	(ABC) transporter
EXW26_11195	COG4473	ABC transporter
EXW26_11205	COG0546	phosphoglycolate phosphatase activity
EXW26_11260	COG0768	penicillin binding
EXW26_11270	COG0204	Acyl-transferase
EXW26_11275	COG1272	protein, Hemolysin III
EXW26_11280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW26_11285	COG0805	protein transport
EXW26_11300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW26_11305	COG1999	signal sequence binding
EXW26_11310	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW26_11315	COG0367	asparagine synthase
EXW26_11330	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW26_11335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_11340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW26_11360	COG1335	isochorismatase
EXW26_11370	COG0668	transmembrane transport
EXW26_11375	COG2203	Gaf domain
EXW26_11375	COG4585	Histidine kinase
EXW26_11380	COG2197	response regulator
EXW26_11385	COG1737	Transcriptional regulator
EXW26_11390	COG1064	alcohol dehydrogenase
EXW26_11405	COG1070	Carbohydrate kinase
EXW26_11415	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW26_11435	COG0517	IMP dehydrogenase activity
EXW26_11435	COG1125	glycine betaine transport
EXW26_11440	COG1174	glycine betaine transport
EXW26_11475	COG1253	flavin adenine dinucleotide binding
EXW26_11480	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_11485	COG5506	Protein of unknown function (DUF1694)
EXW26_11500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW26_11505	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW26_11510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW26_11515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW26_11520	COG0456	acetyltransferase
EXW26_11525	COG3829	transcription factor binding
EXW26_11530	COG1509	lysine 2,3-aminomutase activity
EXW26_11540	COG4479	Belongs to the UPF0346 family
EXW26_11545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW26_11600	COG5293	efflux transmembrane transporter activity
EXW26_11630	COG3064	Membrane
EXW26_11630	COG4991	sh3 domain protein
EXW26_11630	COG0515	serine threonine protein kinase
EXW26_11640	COG0671	phosphoesterase, PA-phosphatase related
EXW26_11645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW26_11650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW26_11710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW26_11735	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_11755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW26_11755	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW26_11765	COG2814	Major facilitator Superfamily
EXW26_11775	COG0372	Belongs to the citrate synthase family
EXW26_11780	COG2079	MmgE PrpD family protein
EXW26_11785	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW26_11790	COG1960	acyl-CoA dehydrogenase activity
EXW26_11795	COG2084	Dehydrogenase
EXW26_11800	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_11805	COG1280	lysine exporter protein (LysE YggA)
EXW26_11810	COG1024	Enoyl-CoA hydratase
EXW26_11825	COG0420	3'-5' exonuclease activity
EXW26_11845	COG2223	nitrite transmembrane transporter activity
EXW26_11850	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_11855	COG1169	isochorismate synthase
EXW26_11860	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW26_11865	COG3433	isochorismatase activity
EXW26_11865	COG1535	isochorismatase
EXW26_11870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW26_11875	COG3251	PFAM MbtH domain protein
EXW26_11880	COG2814	Major facilitator Superfamily
EXW26_11895	COG0776	regulation of translation
EXW26_11905	COG2318	DinB family
EXW26_11910	COG1115	amino acid carrier protein
EXW26_11925	COG2329	Antibiotic biosynthesis monooxygenase
EXW26_11940	COG1187	pseudouridine synthase activity
EXW26_11945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW26_11950	COG3655	Transcriptional regulator
EXW26_11960	COG1136	(ABC) transporter
EXW26_11970	COG0596	Alpha beta hydrolase
EXW26_11985	COG0028	Belongs to the TPP enzyme family
EXW26_12010	COG1253	flavin adenine dinucleotide binding
EXW26_12060	COG1846	Transcriptional regulator
EXW26_12070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_12075	COG1309	transcriptional regulator
EXW26_12085	COG0697	spore germination
EXW26_12090	COG0531	amino acid
EXW26_12105	COG1247	-acetyltransferase
EXW26_12145	COG0596	Alpha beta hydrolase
EXW26_12150	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW26_12160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_12190	COG0583	DNA-binding transcription factor activity
EXW26_12195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW26_12210	COG0583	DNA-binding transcription factor activity
EXW26_12215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW26_12220	COG2258	MOSC domain
EXW26_12230	COG1132	(ABC) transporter
EXW26_12235	COG1132	(ABC) transporter
EXW26_12255	COG1396	sequence-specific DNA binding
EXW26_12290	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW26_12295	COG1595	DNA-templated transcription, initiation
EXW26_12315	COG1649	PFAM Uncharacterised BCR, COG1649
EXW26_12335	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW26_12340	COG2971	BadF BadG BcrA BcrD
EXW26_12410	COG0500	methyltransferase
EXW26_12410	COG3615	Tellurite resistance protein tehB
EXW26_12420	COG0693	protein deglycase activity
EXW26_12430	COG0588	phosphoglycerate mutase activity
EXW26_12450	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW26_12455	COG0110	maltose O-acetyltransferase activity
EXW26_12470	COG1136	(ABC) transporter
EXW26_12485	COG5002	protein histidine kinase activity
EXW26_12490	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_12500	COG1686	Belongs to the peptidase S11 family
EXW26_12525	COG0768	penicillin binding
EXW26_12530	COG0745	RESPONSE REGULATOR receiver
EXW26_12535	COG2205	protein histidine kinase activity
EXW26_12540	COG1136	(ABC) transporter
EXW26_12545	COG0577	efflux transmembrane transporter activity
EXW26_12555	COG1595	DNA-templated transcription, initiation
EXW26_12565	COG0768	penicillin binding
EXW26_12570	COG0768	penicillin binding
EXW26_12605	COG1252	NADH dehydrogenase
EXW26_12610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_12610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_12625	COG0697	spore germination
EXW26_12655	COG3397	chitin binding
EXW26_12660	COG0823	Involved in the tonB-independent uptake of proteins
EXW26_12670	COG1408	metallophosphoesterase
EXW26_12680	COG1131	(ABC) transporter
EXW26_12690	COG1309	transcriptional regulator
EXW26_12700	COG1960	acyl-CoA dehydrogenase activity
EXW26_12705	COG0439	Biotin carboxylase
EXW26_12710	COG0511	ligase activity, forming carbon-carbon bonds
EXW26_12715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW26_12720	COG1024	Enoyl-CoA hydratase
EXW26_12725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW26_12730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW26_12770	COG0572	uridine kinase
EXW26_12775	COG2318	DinB family
EXW26_12805	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW26_12835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW26_12860	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_12865	COG1733	regulation of RNA biosynthetic process
EXW26_12890	COG1309	transcriptional regulator
EXW26_12920	COG0697	spore germination
EXW26_12925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_12955	COG2323	membrane
EXW26_12970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_12975	COG0697	spore germination
EXW26_12995	COG0201	protein transport
EXW26_13005	COG0737	Belongs to the 5'-nucleotidase family
EXW26_13015	COG3227	Zinc metalloprotease (Elastase)
EXW26_13020	COG1523	belongs to the glycosyl hydrolase 13 family
EXW26_13035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_13040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_13045	COG1073	alpha beta
EXW26_13055	COG0577	efflux transmembrane transporter activity
EXW26_13060	COG1136	(ABC) transporter
EXW26_13090	COG5002	protein histidine kinase activity
EXW26_13095	COG0745	RESPONSE REGULATOR receiver
EXW26_13100	COG1011	Hydrolase
EXW26_13125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW26_13130	COG1183	phosphatidylcholine synthase activity
EXW26_13145	COG1132	(ABC) transporter
EXW26_13155	COG3961	Belongs to the TPP enzyme family
EXW26_13175	COG0322	excinuclease ABC activity
EXW26_13200	COG2318	DinB family
EXW26_13215	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW26_13240	COG3878	Protein conserved in bacteria
EXW26_13265	COG1051	belongs to the nudix hydrolase family
EXW26_13270	COG0592	DNA-directed DNA polymerase activity
EXW26_13275	COG2816	NAD+ diphosphatase activity
EXW26_13285	COG2223	nitrite transmembrane transporter activity
EXW26_13290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW26_13300	COG0494	nUDIX hydrolase
EXW26_13320	COG0697	spore germination
EXW26_13325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_13340	COG0584	glycerophosphoryl diester phosphodiesterase
EXW26_13355	COG1733	regulation of RNA biosynthetic process
EXW26_13365	COG2814	Major facilitator Superfamily
EXW26_13380	COG1132	(ABC) transporter
EXW26_13380	COG2375	cellular response to nickel ion
EXW26_13385	COG1132	(ABC) transporter
EXW26_13420	COG0768	penicillin binding
EXW26_13425	COG0671	phosphoesterase, PA-phosphatase related
EXW26_13430	COG0604	alcohol dehydrogenase
EXW26_13435	COG5002	protein histidine kinase activity
EXW26_13440	COG0745	RESPONSE REGULATOR receiver
EXW26_13450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW26_13460	COG2205	protein histidine kinase activity
EXW26_13475	COG1122	ATPase activity
EXW26_13480	COG4720	Psort location CytoplasmicMembrane, score
EXW26_13485	COG1794	racemase activity, acting on amino acids and derivatives
EXW26_13490	COG1819	glycosyl
EXW26_13500	COG0768	penicillin binding
EXW26_13505	COG5002	protein histidine kinase activity
EXW26_13510	COG0561	phosphatase activity
EXW26_13560	COG2124	cytochrome p450
EXW26_13610	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW26_13620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_13625	COG0460	homoserine dehydrogenase
EXW26_13645	COG0577	efflux transmembrane transporter activity
EXW26_13650	COG1136	(ABC) transporter
EXW26_13660	COG0488	(ABC) transporter
EXW26_13665	COG0667	Aldo Keto reductase
EXW26_13670	COG0583	DNA-binding transcription factor activity
EXW26_13675	COG2205	protein histidine kinase activity
EXW26_13680	COG0745	RESPONSE REGULATOR receiver
EXW26_13690	COG3773	Cell wall hydrolase
EXW26_13695	COG0604	alcohol dehydrogenase
EXW26_13725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_13740	COG2959	enzyme of heme biosynthesis
EXW26_13770	COG3483	tryptophan 2,3-dioxygenase activity
EXW26_13775	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW26_13780	COG3844	kynureninase activity
EXW26_13785	COG1309	transcriptional regulator
EXW26_13815	COG1349	DNA-binding transcription factor activity
EXW26_13845	COG2223	nitrite transmembrane transporter activity
EXW26_13855	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_13860	COG0456	acetyltransferase
EXW26_13860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW26_13895	COG4176	ABC-type proline glycine betaine transport system permease component
EXW26_13900	COG0517	IMP dehydrogenase activity
EXW26_13900	COG4175	Glycine betaine
EXW26_13925	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW26_13930	COG2153	protein acetylation
EXW26_13935	COG3397	chitin binding
EXW26_13945	COG1819	glycosyl
EXW26_13960	COG2205	protein histidine kinase activity
EXW26_13965	COG2315	Protein conserved in bacteria
EXW26_14010	COG3973	AAA domain
EXW26_14025	COG2105	PFAM AIG2 family protein
EXW26_14030	COG0514	ATP-dependent DNA helicase (RecQ)
EXW26_14050	COG4637	Psort location Cytoplasmic, score
EXW26_14070	COG1227	inorganic diphosphatase activity
EXW26_14075	COG3397	chitin binding
EXW26_14080	COG2318	DinB family
EXW26_14100	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW26_14105	COG1115	amino acid carrier protein
EXW26_14110	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_14115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW26_14125	COG3938	Belongs to the proline racemase family
EXW26_14130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW26_14180	COG0586	Pfam SNARE associated Golgi protein
EXW26_14195	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW26_14200	COG4166	transmembrane transport
EXW26_14210	COG4948	Mandelate Racemase Muconate Lactonizing
EXW26_14230	COG0667	Aldo Keto reductase
EXW26_14275	COG2936	dipeptidyl-peptidase activity
EXW26_14280	COG5002	protein histidine kinase activity
EXW26_14285	COG0745	RESPONSE REGULATOR receiver
EXW26_14315	COG1164	Oligoendopeptidase f
EXW26_14335	COG1307	EDD domain protein, DegV family
EXW26_14365	COG1335	isochorismatase
EXW26_14380	COG2814	Major facilitator Superfamily
EXW26_14390	COG1664	Polymer-forming cytoskeletal
EXW26_14395	COG0789	Transcriptional regulator
EXW26_14400	COG4533	DNA binding
EXW26_14405	COG2814	Major facilitator Superfamily
EXW26_14405	COG0477	Major facilitator Superfamily
EXW26_14420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW26_14425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW26_14430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW26_14435	COG0438	transferase activity, transferring glycosyl groups
EXW26_14450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW26_14455	COG0438	transferase activity, transferring glycosyl groups
EXW26_14460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW26_14475	COG2261	transglycosylase associated protein
EXW26_14490	COG2226	methyltransferase
EXW26_14525	COG0436	Aminotransferase
EXW26_14530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW26_14555	COG1131	(ABC) transporter
EXW26_14560	COG2188	Transcriptional regulator
EXW26_14605	COG0628	permease
EXW26_14635	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW26_14645	COG0697	spore germination
EXW26_14670	COG4912	Dna alkylation repair
EXW26_14695	COG2814	Major facilitator Superfamily
EXW26_14700	COG1368	sulfuric ester hydrolase activity
EXW26_14710	COG0488	(ABC) transporter
EXW26_14715	COG2409	Drug exporters of the RND superfamily
EXW26_14715	COG1033	growth of symbiont in host cell
EXW26_14725	COG1309	transcriptional regulator
EXW26_14740	COG0287	Prephenate dehydrogenase
EXW26_14755	COG1605	Chorismate mutase
EXW26_14755	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW26_14795	COG1388	LysM domain
EXW26_14795	COG3584	3D domain protein
EXW26_14805	COG0346	lactoylglutathione lyase activity
EXW26_14840	COG0579	oxidoreductase
EXW26_14850	COG2390	Transcriptional regulator
EXW26_14870	COG1830	Aldolase
EXW26_14875	COG2226	methyltransferase
EXW26_14890	COG0346	lactoylglutathione lyase activity
EXW26_14895	COG2329	Antibiotic biosynthesis monooxygenase
EXW26_14915	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW26_14920	COG2207	Transcriptional regulator
EXW26_14925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_14930	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW26_14935	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW26_14940	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW26_14945	COG3239	Fatty acid desaturase
EXW26_14965	COG3655	Transcriptional regulator
EXW26_14980	COG4377	Putative membrane peptidase family (DUF2324)
EXW26_14990	COG3279	Response regulator of the LytR AlgR family
EXW26_15005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_15010	COG0346	lactoylglutathione lyase activity
EXW26_15045	COG0714	Associated with various cellular activities
EXW26_15065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW26_15070	COG0753	catalase activity
EXW26_15080	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW26_15100	COG0778	Nitroreductase
EXW26_15105	COG1846	Transcriptional regulator
EXW26_15125	COG0494	nUDIX hydrolase
EXW26_15145	COG1725	Transcriptional regulator
EXW26_15175	COG2207	Transcriptional regulator
EXW26_15180	COG0456	acetyltransferase
EXW26_15195	COG0697	spore germination
EXW26_15200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_15205	COG1671	Belongs to the UPF0178 family
EXW26_15225	COG0456	acetyltransferase
EXW26_15225	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW26_15250	COG0730	response to heat
EXW26_15260	COG0833	amino acid
EXW26_15270	COG4335	DNA alkylation repair
EXW26_15305	COG0768	penicillin binding
EXW26_15315	COG3104	oligopeptide transport
EXW26_15320	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW26_15335	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW26_15340	COG1984	allophanate hydrolase subunit 2
EXW26_15345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW26_15350	COG1414	Transcriptional regulator
EXW26_15370	COG1960	acyl-CoA dehydrogenase activity
EXW26_15395	COG0640	Transcriptional regulator
EXW26_15415	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW26_15430	COG3848	Pyruvate phosphate dikinase
EXW26_15430	COG0574	Belongs to the PEP-utilizing enzyme family
EXW26_15455	COG1136	(ABC) transporter
EXW26_15490	COG1073	alpha beta
EXW26_15535	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW26_15555	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW26_15560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW26_15565	COG1121	(ABC) transporter
EXW26_15580	COG1999	signal sequence binding
EXW26_15585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW26_15590	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW26_15615	COG0798	PFAM Bile acid sodium symporter
EXW26_15620	COG0346	lactoylglutathione lyase activity
EXW26_15625	COG0640	Transcriptional regulator
EXW26_15675	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_15680	COG1522	sequence-specific DNA binding
EXW26_15695	COG0346	lactoylglutathione lyase activity
EXW26_15715	COG2226	methyltransferase
EXW26_15725	COG2814	Major facilitator Superfamily
EXW26_15750	COG0745	RESPONSE REGULATOR receiver
EXW26_15755	COG3850	Histidine kinase
EXW26_15755	COG5002	protein histidine kinase activity
EXW26_15785	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW26_15825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW26_15835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_15855	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW26_15875	COG1136	(ABC) transporter
EXW26_15880	COG0577	efflux transmembrane transporter activity
EXW26_15900	COG3850	Histidine kinase
EXW26_15900	COG5002	protein histidine kinase activity
EXW26_15915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_15935	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW26_15955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW26_16020	COG2814	Major facilitator Superfamily
EXW26_16040	COG1876	peptidase activity
EXW26_16045	COG2843	Capsule synthesis protein
EXW26_16060	COG0477	Major facilitator Superfamily
EXW26_16075	COG1846	Transcriptional regulator
EXW26_16080	COG2814	Major facilitator Superfamily
EXW26_16095	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EXW26_16105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_16115	COG0789	Transcriptional regulator
EXW26_16150	COG1476	TRANSCRIPTIONal
EXW26_16165	COG1288	antiporter activity
EXW26_16170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW26_16215	COG3718	enzyme involved in inositol metabolism
EXW26_16220	COG0191	fructose-bisphosphate aldolase activity
EXW26_16245	COG0673	inositol 2-dehydrogenase activity
EXW26_16250	COG2814	Major facilitator Superfamily
EXW26_16255	COG1609	Transcriptional regulator
EXW26_16260	COG2003	Belongs to the UPF0758 family
EXW26_16320	COG0494	nUDIX hydrolase
EXW26_16350	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW26_16380	COG0739	heme binding
EXW26_16430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW26_16485	COG4187	Peptidase family M20/M25/M40
EXW26_16500	COG2031	fatty acid transporter
EXW26_16510	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW26_16555	COG1122	ATPase activity
EXW26_16575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW26_16580	COG1288	antiporter activity
EXW26_16585	COG2356	endonuclease I
EXW26_16590	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW26_16615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW26_16635	COG1785	Belongs to the alkaline phosphatase family
EXW26_16640	COG0778	Nitroreductase
EXW26_16645	COG1733	regulation of RNA biosynthetic process
EXW26_16665	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_16675	COG1131	(ABC) transporter
EXW26_16695	COG0494	nUDIX hydrolase
EXW26_16710	COG1011	Hydrolase
EXW26_16715	COG2365	Tyrosine phosphatase family
EXW26_16740	COG0346	lactoylglutathione lyase activity
EXW26_16745	COG1940	carbohydrate kinase activity
EXW26_16750	COG0738	Major facilitator superfamily
EXW26_16755	COG0110	maltose O-acetyltransferase activity
EXW26_16770	COG0628	permease
EXW26_16775	COG2261	transglycosylase associated protein
EXW26_16810	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW26_16820	COG1253	flavin adenine dinucleotide binding
EXW26_16825	COG0789	Transcriptional regulator
EXW26_16830	COG0697	spore germination
EXW26_16840	COG3813	Protein conserved in bacteria
EXW26_16845	COG2706	6-phosphogluconolactonase activity
EXW26_16850	COG1070	Carbohydrate kinase
EXW26_16860	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW26_16865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW26_16880	COG0814	amino acid
EXW26_16900	COG1393	Belongs to the ArsC family
EXW26_16910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_16925	COG0494	nUDIX hydrolase
EXW26_16950	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_16960	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_16965	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW26_16970	COG1733	regulation of RNA biosynthetic process
EXW26_16985	COG1191	sigma factor activity
EXW26_17015	COG1876	peptidase activity
EXW26_17035	COG0741	lytic transglycosylase activity
EXW26_17055	COG5002	protein histidine kinase activity
EXW26_17060	COG0745	RESPONSE REGULATOR receiver
EXW26_17065	COG3344	reverse transcriptase
EXW26_17085	COG0657	acetylesterase activity
EXW26_17095	COG2814	Major facilitator Superfamily
EXW26_17100	COG1309	transcriptional regulator
EXW26_17110	COG3226	Transcriptional regulator
EXW26_17115	COG1280	lysine exporter protein (LysE YggA)
EXW26_17145	COG0814	amino acid
EXW26_17170	COG1151	hydroxylamine reductase activity
EXW26_17215	COG2072	flavoprotein involved in K transport
EXW26_17260	COG1695	Transcriptional regulator
EXW26_17265	COG0604	alcohol dehydrogenase
EXW26_17270	COG1113	amino acid transport
EXW26_17280	COG2814	Major facilitator Superfamily
EXW26_17310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW26_17315	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW26_17335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_17340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_17345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_17350	COG3739	integral membrane protein
EXW26_17375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_17380	COG0583	DNA-binding transcription factor activity
EXW26_17405	COG1193	negative regulation of DNA recombination
EXW26_17425	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW26_17430	COG1164	Oligoendopeptidase f
EXW26_17435	COG2957	Belongs to the agmatine deiminase family
EXW26_17455	COG3781	membrane
EXW26_17470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW26_17505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW26_17510	COG0640	Transcriptional regulator
EXW26_17515	COG0604	alcohol dehydrogenase
EXW26_17520	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW26_17530	COG0457	Tetratricopeptide repeat
EXW26_17535	COG2808	Putative FMN-binding domain
EXW26_17545	COG0277	FAD linked oxidase domain protein
EXW26_17565	COG1285	pathogenesis
EXW26_17580	COG2514	catechol 2,3-dioxygenase activity
EXW26_17585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW26_17590	COG1126	abc transporter atp-binding protein
EXW26_17595	COG0765	amino acid transport
EXW26_17600	COG2720	vancomycin resistance protein
EXW26_17625	COG1278	Cold shock
EXW26_17635	COG0716	FMN binding
EXW26_17645	COG0494	nUDIX hydrolase
EXW26_17665	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_17675	COG0165	Argininosuccinate lyase
EXW26_17690	COG4145	pantothenate transmembrane transporter activity
EXW26_17700	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_17705	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_17715	COG1657	PFAM Prenyltransferase squalene oxidase
EXW26_17720	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW26_17725	COG2962	Rard protein
EXW26_17730	COG3326	Membrane
EXW26_17735	COG0531	amino acid
EXW26_17765	COG2226	methyltransferase
EXW26_17770	COG4166	transmembrane transport
EXW26_17775	COG4166	transmembrane transport
EXW26_17780	COG4166	transmembrane transport
EXW26_17790	COG1131	(ABC) transporter
EXW26_17810	COG0673	inositol 2-dehydrogenase activity
EXW26_17815	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW26_17820	COG0187	DNA topoisomerase II activity
EXW26_17825	COG1832	CoA-binding protein
EXW26_17830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW26_17835	COG0745	RESPONSE REGULATOR receiver
EXW26_17845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW26_17845	COG1328	CTP reductase activity
EXW26_17855	COG4841	protein insertion into membrane
EXW26_17860	COG0824	Thioesterase
EXW26_17885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW26_17900	COG1266	CAAX protease self-immunity
EXW26_17905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW26_17935	COG2211	Major facilitator Superfamily
EXW26_17945	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW26_17960	COG0183	Belongs to the thiolase family
EXW26_17965	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_17970	COG1268	BioY protein
EXW26_17975	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_17980	COG1396	sequence-specific DNA binding
EXW26_18020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_18035	COG5002	protein histidine kinase activity
EXW26_18045	COG0400	carboxylic ester hydrolase activity
EXW26_18050	COG0346	lactoylglutathione lyase activity
EXW26_18060	COG0069	glutamate synthase activity
EXW26_18065	COG1902	pentaerythritol trinitrate reductase activity
EXW26_18070	COG1329	Transcriptional regulator
EXW26_18075	COG0010	Belongs to the arginase family
EXW26_18085	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW26_18090	COG2986	histidine ammonia-lyase
EXW26_18100	COG2226	methyltransferase
EXW26_18130	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW26_18135	COG0785	Cytochrome C biogenesis protein
EXW26_18150	COG1473	amidohydrolase
EXW26_18155	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW26_18160	COG1131	(ABC) transporter
EXW26_18170	COG0583	DNA-binding transcription factor activity
EXW26_18180	COG1346	cytolysis
EXW26_18195	COG0730	response to heat
EXW26_18205	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW26_18205	COG3409	Peptidoglycan-binding domain 1 protein
EXW26_18225	COG1132	(ABC) transporter
EXW26_18230	COG1132	(ABC) transporter
EXW26_18235	COG3763	UPF0154 protein
EXW26_18255	COG3639	organic phosphonate transmembrane transporter activity
EXW26_18265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW26_18270	COG0737	Belongs to the 5'-nucleotidase family
EXW26_18280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW26_18285	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW26_18300	COG1695	Transcriptional regulator
EXW26_18305	COG1132	(ABC) transporter
EXW26_18340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW26_18350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW26_18355	COG3420	alginic acid biosynthetic process
EXW26_18355	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW26_18385	COG1216	Glycosyl transferase, family 2
EXW26_18405	COG0463	Glycosyl transferase, family 2
EXW26_18405	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW26_18410	COG0438	transferase activity, transferring glycosyl groups
EXW26_18415	COG0438	transferase activity, transferring glycosyl groups
EXW26_18420	COG1086	Polysaccharide biosynthesis protein
EXW26_18425	COG0489	protein tyrosine kinase activity
EXW26_18430	COG3944	biosynthesis protein
EXW26_18435	COG0174	glutamine synthetase
EXW26_18440	COG0789	Transcriptional regulator
EXW26_18445	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW26_18450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW26_18455	COG2860	membrane
EXW26_18460	COG0464	growth
EXW26_18480	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW26_18490	COG1388	LysM domain
EXW26_18490	COG3584	3D domain protein
EXW26_18495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW26_18495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW26_18495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW26_18500	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW26_18505	COG1349	DNA-binding transcription factor activity
EXW26_18510	COG1979	alcohol dehydrogenase
EXW26_18515	COG2322	membrane
EXW26_18525	COG1113	amino acid transport
EXW26_18540	COG1473	amidohydrolase
EXW26_18545	COG1408	metallophosphoesterase
EXW26_18550	COG2116	formate transmembrane transporter activity
EXW26_18565	COG2217	Heavy metal translocating P-type atpase
EXW26_18570	COG2608	mercury ion transmembrane transporter activity
EXW26_18575	COG1937	Protein conserved in bacteria
EXW26_18605	COG4566	intracellular signal transduction
EXW26_18610	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW26_18615	COG2819	hydrolase of the alpha beta superfamily
EXW26_18620	COG1120	ATPase activity
EXW26_18625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_18630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_18635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_18640	COG0708	Exodeoxyribonuclease III
EXW26_18645	COG2169	Transcriptional regulator
EXW26_18650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW26_18655	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW26_18665	COG2706	6-phosphogluconolactonase activity
EXW26_18670	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW26_18675	COG2364	Membrane
EXW26_18695	COG0346	lactoylglutathione lyase activity
EXW26_18700	COG3300	MHYT domain
EXW26_18700	COG5001	Diguanylate cyclase
EXW26_18740	COG1346	cytolysis
EXW26_18750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_18755	COG2945	thiolester hydrolase activity
EXW26_18755	COG0596	Alpha beta hydrolase
EXW26_18760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW26_18770	COG2188	Transcriptional regulator
EXW26_18775	COG2723	6-phospho-beta-galactosidase activity
EXW26_18780	COG0840	transmembrane signaling receptor activity
EXW26_18790	COG3773	Cell wall hydrolase
EXW26_18805	COG1368	sulfuric ester hydrolase activity
EXW26_18810	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW26_18825	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW26_18835	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW26_18840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW26_18850	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW26_18855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW26_18860	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW26_18865	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW26_18865	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW26_18875	COG2359	stage V sporulation protein S
EXW26_18880	COG1692	metallophosphoesterase
EXW26_18885	COG1418	mRNA catabolic process
EXW26_18890	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW26_18895	COG1546	Belongs to the CinA family
EXW26_18895	COG1058	Belongs to the CinA family
EXW26_18900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW26_18905	COG1426	Protein conserved in bacteria
EXW26_18920	COG0300	oxidoreductase activity
EXW26_18925	COG0612	Peptidase, M16
EXW26_18930	COG0612	Peptidase, M16
EXW26_18935	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW26_18940	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW26_18945	COG3845	ABC transporter
EXW26_18950	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW26_18955	COG2188	Transcriptional regulator
EXW26_18960	COG1674	ftsk spoiiie
EXW26_18970	COG0740	serine-type endopeptidase activity
EXW26_18975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW26_18985	COG0527	aspartate kinase activity
EXW26_18990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW26_18995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW26_19000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW26_19005	COG1873	PFAM PRC-barrel domain
EXW26_19010	COG0612	Peptidase, M16
EXW26_19015	COG0726	polysaccharide deacetylase
EXW26_19020	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW26_19030	COG0196	riboflavin kinase activity
EXW26_19040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW26_19045	COG1550	Protein conserved in bacteria
EXW26_19050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW26_19055	COG1358	cellular component organization or biogenesis
EXW26_19060	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW26_19065	COG0195	Participates in both transcription termination and antitermination
EXW26_19070	COG0779	Required for maturation of 30S ribosomal subunits
EXW26_19080	COG0442	prolyl-tRNA aminoacylation
EXW26_19085	COG0750	zinc metalloprotease
EXW26_19095	COG4589	Belongs to the CDS family
EXW26_19105	COG0233	cytoplasmic translational termination
EXW26_19110	COG0528	UMP kinase activity
EXW26_19115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW26_19120	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW26_19125	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW26_19130	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW26_19135	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW26_19140	COG4974	Belongs to the 'phage' integrase family
EXW26_19145	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW26_19150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW26_19155	COG0758	DNA mediated transformation
EXW26_19160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW26_19165	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW26_19170	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW26_19185	COG0335	large ribosomal subunit rRNA binding
EXW26_19190	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW26_19195	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW26_19200	COG1837	Belongs to the UPF0109 family
EXW26_19210	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW26_19215	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EXW26_19220	COG0552	protein localization to endoplasmic reticulum
EXW26_19225	COG1196	nuclear chromosome segregation
EXW26_19230	COG0571	ribonuclease III activity
EXW26_19235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW26_19240	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_19245	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW26_19250	COG0416	fatty acid biosynthetic process
EXW26_19255	COG2050	protein possibly involved in aromatic compounds catabolism
EXW26_19255	COG1349	DNA-binding transcription factor activity
EXW26_19260	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW26_19265	COG1461	Dihydroxyacetone kinase
EXW26_19270	COG1302	Protein conserved in bacteria
EXW26_19285	COG1564	THIamine pyrophosphokinase
EXW26_19290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW26_19300	COG2815	serine threonine protein kinase
EXW26_19300	COG0515	serine threonine protein kinase
EXW26_19305	COG0631	protein serine/threonine phosphatase activity
EXW26_19310	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW26_19315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW26_19315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW26_19320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW26_19325	COG0242	peptide deformylase activity
EXW26_19330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW26_19335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW26_19340	COG1758	RNA polymerase activity
EXW26_19355	COG1561	YicC-like family, N-terminal region
EXW26_19360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW26_19375	COG0006	proline dipeptidase activity
EXW26_19435	COG0167	dihydroorotate dehydrogenase activity
EXW26_19440	COG0543	2 iron, 2 sulfur cluster binding
EXW26_19445	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW26_19455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW26_19460	COG0540	Belongs to the ATCase OTCase family
EXW26_19470	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW26_19475	COG0564	pseudouridine synthase activity
EXW26_19480	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW26_19490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW26_19495	COG3599	regulation of cell shape
EXW26_19500	COG2302	S4 RNA-binding domain
EXW26_19505	COG0762	integral membrane protein
EXW26_19510	COG1799	cell septum assembly
EXW26_19515	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW26_19525	COG1873	PFAM PRC-barrel domain
EXW26_19530	COG1191	sigma factor activity
EXW26_19535	COG1191	sigma factor activity
EXW26_19545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW26_19550	COG0849	cell division
EXW26_19555	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW26_19570	COG0772	Belongs to the SEDS family
EXW26_19575	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW26_19580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW26_19585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW26_19590	COG0768	penicillin binding
EXW26_19595	COG0768	penicillin binding
EXW26_19605	COG0275	rRNA processing
EXW26_19610	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW26_19615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW26_19620	COG0454	-acetyltransferase
EXW26_19630	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW26_19635	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW26_19640	COG1323	Belongs to the UPF0348 family
EXW26_19645	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW26_19650	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW26_19655	COG3314	Sporulation integral membrane protein YlbJ
EXW26_19660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EXW26_19665	COG0742	ribosomal rna small subunit methyltransferase
EXW26_19675	COG4471	UPF0298 protein
EXW26_19680	COG3679	Belongs to the UPF0342 family
EXW26_19685	COG0406	alpha-ribazole phosphatase activity
EXW26_19700	COG2340	Cysteine-rich secretory protein family
EXW26_19710	COG3336	cytochrome c oxidase
EXW26_19735	COG0109	protoheme IX farnesyltransferase activity
EXW26_19740	COG1612	heme a metabolic process
EXW26_19745	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW26_19755	COG0772	Belongs to the SEDS family
EXW26_19760	COG4838	Belongs to the UPF0358 family
EXW26_19765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW26_19770	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW26_19780	COG4896	Protein conserved in bacteria
EXW26_19795	COG1217	gtp-binding protein TYPA
EXW26_19805	COG0483	inositol monophosphate 1-phosphatase activity
EXW26_19815	COG4493	Belongs to the UPF0637 family
EXW26_19820	COG4476	Belongs to the UPF0223 family
EXW26_19830	COG1982	Orn Lys Arg decarboxylase major
EXW26_19875	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW26_19880	COG0022	dehydrogenase e1 component
EXW26_19885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW26_19900	COG0561	phosphatase activity
EXW26_19910	COG5503	Protein of unknown function (DUF1447)
EXW26_19915	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW26_19920	COG0569	domain protein
EXW26_19930	COG1473	amidohydrolase
EXW26_19935	COG2171	N-acyltransferase activity
EXW26_19940	COG0583	DNA-binding transcription factor activity
EXW26_19945	COG0517	IMP dehydrogenase activity
EXW26_19955	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW26_19965	COG4703	Protein of unknown function (DUF1797)
EXW26_19980	COG2200	EAL domain
EXW26_19985	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_19990	COG1408	metallophosphoesterase
EXW26_20035	COG2814	Major facilitator Superfamily
EXW26_20045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW26_20055	COG3209	COG3209 Rhs family protein
EXW26_20065	COG2205	protein histidine kinase activity
EXW26_20075	COG0436	Aminotransferase
EXW26_20080	COG1609	Transcriptional regulator
EXW26_20085	COG3833	ABC-type maltose transport systems, permease component
EXW26_20090	COG1175	transmembrane transport
EXW26_20095	COG2182	Extracellular solute-binding protein
EXW26_20105	COG0366	Alpha amylase catalytic
EXW26_20110	COG3842	ATPase activity
EXW26_20155	COG0183	Belongs to the thiolase family
EXW26_20190	COG1695	Transcriptional regulator
EXW26_20195	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_20205	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW26_20210	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW26_20215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW26_20220	COG0436	Aminotransferase
EXW26_20225	COG1850	ribulose-bisphosphate carboxylase activity
EXW26_20230	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW26_20235	COG0235	Class ii aldolase
EXW26_20240	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW26_20255	COG2084	Dehydrogenase
EXW26_20265	COG2199	diguanylate cyclase activity
EXW26_20270	COG0778	Nitroreductase
EXW26_20295	COG1263	PTS System
EXW26_20295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW26_20295	COG2190	(PTS) system
EXW26_20300	COG3711	transcriptional antiterminator
EXW26_20310	COG2188	Transcriptional regulator
EXW26_20315	COG0363	glucosamine-6-phosphate deaminase activity
EXW26_20320	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW26_20330	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW26_20340	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW26_20350	COG1547	Domain of unknown function (DUF309)
EXW26_20360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW26_20365	COG4086	secreted protein
EXW26_20370	COG0561	phosphatase activity
EXW26_20375	COG0697	spore germination
EXW26_20390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_20415	COG0733	neurotransmitter:sodium symporter activity
EXW26_20435	COG1686	Belongs to the peptidase S11 family
EXW26_20440	COG1725	Transcriptional regulator
EXW26_20445	COG1131	(ABC) transporter
EXW26_20465	COG1846	Transcriptional regulator
EXW26_20480	COG0598	Magnesium transport protein CorA
EXW26_20495	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW26_20505	COG4974	Belongs to the 'phage' integrase family
EXW26_20515	COG0735	belongs to the Fur family
EXW26_20520	COG1300	Membrane
EXW26_20540	COG0667	Aldo Keto reductase
EXW26_20545	COG0656	L-ascorbic acid biosynthetic process
EXW26_20550	COG0456	acetyltransferase
EXW26_20550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW26_20560	COG0737	Belongs to the 5'-nucleotidase family
EXW26_20560	COG4085	toxin activity
EXW26_20560	COG1525	nuclease
EXW26_20565	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW26_20575	COG0596	Alpha beta hydrolase
EXW26_20580	COG2056	Na+-H+ antiporter family
EXW26_20585	COG1609	Transcriptional regulator
EXW26_20590	COG0456	acetyltransferase
EXW26_20595	COG1073	alpha beta
EXW26_20610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW26_20610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW26_20615	COG0307	riboflavin synthase, alpha
EXW26_20620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW26_20620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW26_20635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW26_20640	COG4106	trans-aconitate 2-methyltransferase activity
EXW26_20645	COG2226	methyltransferase
EXW26_20645	COG1073	alpha beta
EXW26_20650	COG0156	8-amino-7-oxononanoate synthase activity
EXW26_20660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW26_20670	COG1757	Na H antiporter
EXW26_20675	COG0737	Belongs to the 5'-nucleotidase family
EXW26_20685	COG1522	sequence-specific DNA binding
EXW26_20710	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW26_20720	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW26_20735	COG0300	oxidoreductase activity
EXW26_20740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_20745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW26_20750	COG1760	l-serine dehydratase
EXW26_20755	COG1760	l-serine dehydratase
EXW26_20765	COG1234	tRNA 3'-trailer cleavage
EXW26_20800	COG1131	(ABC) transporter
EXW26_20825	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW26_20830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_20840	COG1376	ErfK ybiS ycfS ynhG family protein
EXW26_20845	COG4129	membrane
EXW26_20850	COG1126	abc transporter atp-binding protein
EXW26_20855	COG0765	amino acid transport
EXW26_20860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW26_20875	COG2323	membrane
EXW26_20880	COG0772	Belongs to the SEDS family
EXW26_20890	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW26_20895	COG0022	dehydrogenase e1 component
EXW26_20900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW26_20905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW26_20910	COG3426	butyrate kinase activity
EXW26_20920	COG0280	phosphate acetyltransferase
EXW26_20930	COG3829	transcription factor binding
EXW26_20930	COG3290	protein histidine kinase activity
EXW26_20940	COG0584	glycerophosphoryl diester phosphodiesterase
EXW26_20945	COG3093	addiction module antidote protein HigA
EXW26_20955	COG0745	RESPONSE REGULATOR receiver
EXW26_20965	COG0750	zinc metalloprotease
EXW26_20970	COG0497	DNA recombination
EXW26_20975	COG1438	arginine binding
EXW26_20980	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW26_20985	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW26_20990	COG0142	geranyltranstransferase activity
EXW26_20995	COG1722	exodeoxyribonuclease VII activity
EXW26_21000	COG1570	exodeoxyribonuclease VII activity
EXW26_21005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW26_21010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW26_21015	COG1302	Protein conserved in bacteria
EXW26_21020	COG0439	Biotin carboxylase
EXW26_21025	COG0511	ligase activity, forming carbon-carbon bonds
EXW26_21070	COG3854	ATPases associated with a variety of cellular activities
EXW26_21090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW26_21095	COG0006	proline dipeptidase activity
EXW26_21100	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW26_21110	COG3872	metal-dependent enzyme
EXW26_21120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW26_21125	COG1321	iron dependent repressor
EXW26_21155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_21165	COG1609	Transcriptional regulator
EXW26_21175	COG2076	Multidrug Resistance protein
EXW26_21180	COG2076	Multidrug Resistance protein
EXW26_21215	COG1725	Transcriptional regulator
EXW26_21230	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW26_21235	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW26_21240	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW26_21245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW26_21275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW26_21300	COG4970	Tfp pilus assembly protein FimT
EXW26_21310	COG1459	type II secretion system
EXW26_21315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW26_21370	COG0646	methionine synthase
EXW26_21370	COG1410	methionine synthase
EXW26_21375	COG0646	methionine synthase
EXW26_21375	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW26_21380	COG0626	cystathionine gamma-synthase activity
EXW26_21385	COG0626	cystathionine gamma-synthase activity
EXW26_21400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_21410	COG1940	carbohydrate kinase activity
EXW26_21415	COG4483	Protein conserved in bacteria
EXW26_21420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW26_21425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW26_21430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW26_21435	COG0704	Plays a role in the regulation of phosphate uptake
EXW26_21450	COG0581	inorganic phosphate transmembrane transporter activity
EXW26_21455	COG0573	inorganic phosphate transmembrane transporter activity
EXW26_21460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW26_21465	COG0768	penicillin binding
EXW26_21470	COG0477	Major facilitator Superfamily
EXW26_21475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW26_21495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW26_21500	COG0735	belongs to the Fur family
EXW26_21505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW26_21510	COG1121	(ABC) transporter
EXW26_21515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_21525	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW26_21540	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW26_21545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW26_21550	COG2384	SAM-dependent methyltransferase
EXW26_21560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW26_21565	COG0358	DNA primase activity
EXW26_21575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW26_21580	COG0517	IMP dehydrogenase activity
EXW26_21585	COG1381	Involved in DNA repair and RecF pathway recombination
EXW26_21595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW26_21600	COG0295	cytidine deaminase activity
EXW26_21605	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW26_21610	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW26_21615	COG1480	7TM receptor with intracellular HD hydrolase
EXW26_21620	COG1702	phosphate starvation-inducible protein PhoH
EXW26_21635	COG1610	YqeY-like protein
EXW26_21640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW26_21645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW26_21650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW26_21660	COG0484	heat shock protein binding
EXW26_21665	COG0443	Heat shock 70 kDa protein
EXW26_21675	COG1420	regulation of RNA biosynthetic process
EXW26_21680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW26_21685	COG1733	regulation of RNA biosynthetic process
EXW26_21690	COG0481	GTPase activity
EXW26_21700	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW26_21705	COG0268	Binds directly to 16S ribosomal RNA
EXW26_21710	COG1466	dna polymerase III delta subunit
EXW26_21720	COG0658	competence protein
EXW26_21720	COG2333	competence protein COMEC
EXW26_21725	COG2131	deaminase
EXW26_21730	COG1555	photosystem II stabilization
EXW26_21730	COG1596	polysaccharide export
EXW26_21735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW26_21740	COG2226	methyltransferase
EXW26_21745	COG0799	negative regulation of ribosome biogenesis
EXW26_21750	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW26_21755	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW26_21760	COG1534	Rna-binding protein
EXW26_21765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW26_21770	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW26_21775	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW26_21785	COG0688	phosphatidylethanolamine metabolic process
EXW26_21795	COG1595	DNA-templated transcription, initiation
EXW26_21800	COG2357	RelA SpoT domain protein
EXW26_21810	COG1785	Belongs to the alkaline phosphatase family
EXW26_21820	COG2267	carboxylic ester hydrolase activity
EXW26_21855	COG1404	Belongs to the peptidase S8 family
EXW26_21860	COG3186	Phenylalanine-4-hydroxylase
EXW26_21865	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW26_21870	COG2514	catechol 2,3-dioxygenase activity
EXW26_21875	COG2259	Doxx family
EXW26_21915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_21925	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_21925	COG1454	alcohol dehydrogenase
EXW26_21930	COG0626	cystathionine gamma-synthase activity
EXW26_21935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW26_21940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW26_21945	COG2226	methyltransferase
EXW26_21960	COG0768	penicillin binding
EXW26_21965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW26_21970	COG0572	uridine kinase
EXW26_21975	COG0826	peptidase U32
EXW26_21980	COG0826	peptidase U32
EXW26_21985	COG4122	O-methyltransferase activity
EXW26_21990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW26_22000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW26_22005	COG4472	Bacterial protein of unknown function (DUF965)
EXW26_22010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW26_22020	COG0628	permease
EXW26_22040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW26_22050	COG0482	sulfurtransferase activity
EXW26_22055	COG1104	cysteine desulfurase activity
EXW26_22060	COG1959	2 iron, 2 sulfur cluster binding
EXW26_22065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW26_22080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW26_22085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW26_22095	COG1490	D-aminoacyl-tRNA deacylase activity
EXW26_22100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW26_22105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW26_22110	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW26_22110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW26_22115	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW26_22120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW26_22120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW26_22130	COG2244	polysaccharide biosynthetic process
EXW26_22135	COG2323	membrane
EXW26_22145	COG1862	Preprotein translocase
EXW26_22150	COG0343	queuine tRNA-ribosyltransferase activity
EXW26_22155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW26_22165	COG2255	four-way junction helicase activity
EXW26_22170	COG0632	four-way junction helicase activity
EXW26_22175	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW26_22200	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW26_22205	COG0157	Belongs to the NadC ModD family
EXW26_22210	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW26_22215	COG1104	cysteine desulfurase activity
EXW26_22220	COG1827	regulation of RNA biosynthetic process
EXW26_22225	COG2258	MOSC domain
EXW26_22230	COG0077	Prephenate dehydratase
EXW26_22235	COG0577	efflux transmembrane transporter activity
EXW26_22240	COG0577	efflux transmembrane transporter activity
EXW26_22245	COG1136	(ABC) transporter
EXW26_22250	COG5002	protein histidine kinase activity
EXW26_22255	COG0745	RESPONSE REGULATOR receiver
EXW26_22260	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW26_22265	COG3290	protein histidine kinase activity
EXW26_22275	COG2868	ribosomal protein
EXW26_22285	COG1530	ribonuclease E activity
EXW26_22290	COG1994	Peptidase M50
EXW26_22295	COG0739	heme binding
EXW26_22300	COG2894	cell division
EXW26_22305	COG0850	regulation of cytokinetic process
EXW26_22320	COG1077	Cell shape determining protein MreB Mrl
EXW26_22325	COG2003	Belongs to the UPF0758 family
EXW26_22330	COG0424	maF-like protein
EXW26_22345	COG0285	dihydrofolate synthase activity
EXW26_22360	COG1388	LysM domain
EXW26_22365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW26_22370	COG0113	porphobilinogen synthase activity
EXW26_22375	COG1587	Uroporphyrinogen-III synthase
EXW26_22380	COG0181	hydroxymethylbilane synthase activity
EXW26_22385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW26_22390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW26_22395	COG1846	Transcriptional regulator
EXW26_22400	COG1764	response to oxidative stress
EXW26_22405	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW26_22415	COG1067	ATP-dependent peptidase activity
EXW26_22415	COG0470	DNA polymerase III
EXW26_22425	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW26_22455	COG0622	Phosphoesterase
EXW26_22465	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW26_22470	COG5401	PFAM Sporulation and spore germination
EXW26_22480	COG0477	Major facilitator Superfamily
EXW26_22490	COG1309	transcriptional regulator
EXW26_22500	COG2197	response regulator
EXW26_22505	COG2233	PERMEase
EXW26_22510	COG0402	S-adenosylhomocysteine deaminase activity
EXW26_22515	COG1983	PspC domain protein
EXW26_22520	COG1396	sequence-specific DNA binding
EXW26_22525	COG0697	spore germination
EXW26_22535	COG1959	2 iron, 2 sulfur cluster binding
EXW26_22540	COG1668	transmembrane transport
EXW26_22545	COG4152	abc transporter atp-binding protein
EXW26_22550	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW26_22555	COG1360	Flagellar Motor Protein
EXW26_22560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW26_22570	COG1876	peptidase activity
EXW26_22575	COG0824	Thioesterase
EXW26_22580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW26_22585	COG1053	succinate dehydrogenase
EXW26_22590	COG2009	succinate dehydrogenase
EXW26_22595	COG1719	4-vinyl reductase, 4VR
EXW26_22600	COG0322	excinuclease ABC activity
EXW26_22605	COG3118	belongs to the thioredoxin family
EXW26_22610	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW26_22615	COG2086	electron transfer activity
EXW26_22620	COG1024	Enoyl-CoA hydratase
EXW26_22625	COG1309	transcriptional regulator
EXW26_22630	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_22655	COG2318	DinB family
EXW26_22680	COG1131	(ABC) transporter
EXW26_22685	COG2205	protein histidine kinase activity
EXW26_22690	COG0745	RESPONSE REGULATOR receiver
EXW26_22695	COG4895	conserved protein (DUF2196)
EXW26_22700	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW26_22705	COG2329	Antibiotic biosynthesis monooxygenase
EXW26_22710	COG4509	Sortase family
EXW26_22715	COG1120	ATPase activity
EXW26_22730	COG5386	Cell surface protein
EXW26_22740	COG5386	Cell surface protein
EXW26_22745	COG1114	Component of the transport system for branched-chain amino acids
EXW26_22755	COG1193	negative regulation of DNA recombination
EXW26_22760	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW26_22760	COG1796	DNA polymerase
EXW26_22765	COG1286	toxin biosynthetic process
EXW26_22770	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW26_22775	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW26_22800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW26_22805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW26_22820	COG1418	mRNA catabolic process
EXW26_22850	COG2814	Major facilitator Superfamily
EXW26_22855	COG1566	PFAM secretion protein HlyD family protein
EXW26_22860	COG1309	transcriptional regulator
EXW26_22865	COG1363	Peptidase, m42
EXW26_22875	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW26_22890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW26_22900	COG1484	DNA-dependent DNA replication
EXW26_22905	COG3611	Membrane attachment protein
EXW26_22910	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW26_22915	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW26_22920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW26_22925	COG0237	dephospho-CoA kinase activity
EXW26_22930	COG1971	Probably functions as a manganese efflux pump
EXW26_22940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW26_22940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW26_22945	COG5002	protein histidine kinase activity
EXW26_22950	COG0745	RESPONSE REGULATOR receiver
EXW26_22965	COG0039	L-malate dehydrogenase activity
EXW26_22970	COG0538	isocitrate dehydrogenase activity
EXW26_22975	COG0372	Belongs to the citrate synthase family
EXW26_23000	COG0628	permease
EXW26_23005	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW26_23015	COG0205	6-phosphofructokinase activity
EXW26_23025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW26_23030	COG1725	Transcriptional regulator
EXW26_23035	COG0281	malic enzyme
EXW26_23040	COG0587	DNA-directed DNA polymerase activity
EXW26_23055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW26_23075	COG4109	DRTGG domain
EXW26_23080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW26_23085	COG0006	proline dipeptidase activity
EXW26_23130	COG0662	Cupin 2, conserved barrel domain protein
EXW26_23140	COG1476	TRANSCRIPTIONal
EXW26_23155	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_23160	COG0589	response to stress
EXW26_23180	COG0165	Argininosuccinate lyase
EXW26_23185	COG0137	argininosuccinate synthase activity
EXW26_23200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_23215	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW26_23220	COG0827	DNA restriction-modification system
EXW26_23225	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW26_23230	COG3874	Sporulation protein YtfJ
EXW26_23245	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW26_23255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW26_23270	COG1104	cysteine desulfurase activity
EXW26_23275	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW26_23290	COG1309	transcriptional regulator
EXW26_23295	COG1956	GAF domain-containing protein
EXW26_23300	COG0626	cystathionine gamma-synthase activity
EXW26_23305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW26_23335	COG1595	DNA-templated transcription, initiation
EXW26_23345	COG0110	maltose O-acetyltransferase activity
EXW26_23350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW26_23355	COG0454	-acetyltransferase
EXW26_23360	COG0517	IMP dehydrogenase activity
EXW26_23365	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW26_23380	COG0745	RESPONSE REGULATOR receiver
EXW26_23385	COG5002	protein histidine kinase activity
EXW26_23390	COG0666	response to abiotic stimulus
EXW26_23400	COG1970	mechanosensitive ion channel activity
EXW26_23425	COG1609	Transcriptional regulator
EXW26_23430	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW26_23430	COG1605	Chorismate mutase
EXW26_23435	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW26_23435	COG1605	Chorismate mutase
EXW26_23440	COG4851	CamS sex pheromone cAM373 precursor
EXW26_23445	COG3118	belongs to the thioredoxin family
EXW26_23455	COG2309	aminopeptidase activity
EXW26_23480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_23485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW26_23495	COG1674	ftsk spoiiie
EXW26_23510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW26_23515	COG4848	Belongs to the UPF0354 family
EXW26_23520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW26_23525	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW26_23530	COG1363	Peptidase, m42
EXW26_23540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_23545	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW26_23555	COG0510	thiamine kinase activity
EXW26_23560	COG1523	belongs to the glycosyl hydrolase 13 family
EXW26_23570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW26_23575	COG1349	DNA-binding transcription factor activity
EXW26_23580	COG1187	pseudouridine synthase activity
EXW26_23585	COG2244	polysaccharide biosynthetic process
EXW26_23590	COG2081	HI0933 family
EXW26_23595	COG2814	Major facilitator Superfamily
EXW26_23605	COG3832	glyoxalase III activity
EXW26_23625	COG1329	Transcriptional regulator
EXW26_23650	COG0314	molybdopterin synthase activity
EXW26_23655	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW26_23660	COG0303	'Molybdopterin
EXW26_23665	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW26_23670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW26_23675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW26_23700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_23710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW26_23750	COG0495	leucyl-tRNA aminoacylation
EXW26_23755	COG2814	Major facilitator Superfamily
EXW26_23760	COG0475	glutathione-regulated potassium exporter activity
EXW26_23765	COG0490	domain, Protein
EXW26_23770	COG0582	viral genome integration into host DNA
EXW26_23785	COG1136	(ABC) transporter
EXW26_23805	COG1242	4 iron, 4 sulfur cluster binding
EXW26_23810	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW26_23820	COG1794	racemase activity, acting on amino acids and derivatives
EXW26_23835	COG2267	carboxylic ester hydrolase activity
EXW26_23840	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW26_23845	COG0671	phosphoesterase, PA-phosphatase related
EXW26_23850	COG0438	transferase activity, transferring glycosyl groups
EXW26_23875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW26_23880	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW26_23905	COG5002	protein histidine kinase activity
EXW26_23910	COG3852	Histidine kinase
EXW26_23915	COG0753	catalase activity
EXW26_23920	COG2267	carboxylic ester hydrolase activity
EXW26_23925	COG1368	sulfuric ester hydrolase activity
EXW26_23930	COG4895	conserved protein (DUF2196)
EXW26_23945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW26_23950	COG1116	anion transmembrane transporter activity
EXW26_23955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW26_23980	COG0494	nUDIX hydrolase
EXW26_24025	COG2076	Multidrug Resistance protein
EXW26_24030	COG2076	Multidrug Resistance protein
EXW26_24035	COG0789	Transcriptional regulator
EXW26_24040	COG1854	S-ribosylhomocysteine lyase activity
EXW26_24050	COG0288	reversible hydration of carbon dioxide
EXW26_24055	COG1271	oxidase subunit
EXW26_24060	COG1294	oxidase, subunit
EXW26_24080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_24105	COG1842	Phage shock protein A
EXW26_24135	COG5002	protein histidine kinase activity
EXW26_24140	COG0745	RESPONSE REGULATOR receiver
EXW26_24165	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW26_24170	COG1597	lipid kinase activity
EXW26_24185	COG1136	(ABC) transporter
EXW26_24215	COG5002	protein histidine kinase activity
EXW26_24225	COG0586	Pfam SNARE associated Golgi protein
EXW26_24240	COG0577	efflux transmembrane transporter activity
EXW26_24245	COG1136	(ABC) transporter
EXW26_24250	COG3708	Transcriptional regulator
EXW26_24250	COG2207	Transcriptional regulator
EXW26_24260	COG1131	(ABC) transporter
EXW26_24265	COG5658	integral membrane protein
EXW26_24270	COG0640	Transcriptional regulator
EXW26_24275	COG0745	RESPONSE REGULATOR receiver
EXW26_24280	COG2205	protein histidine kinase activity
EXW26_24285	COG0577	efflux transmembrane transporter activity
EXW26_24290	COG0577	efflux transmembrane transporter activity
EXW26_24295	COG1136	(ABC) transporter
EXW26_24300	COG0577	efflux transmembrane transporter activity
EXW26_24315	COG2188	Transcriptional regulator
EXW26_24335	COG3964	amidohydrolase
EXW26_24355	COG4948	Mandelate Racemase Muconate Lactonizing
EXW26_24360	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_24365	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW26_24370	COG0596	Alpha beta hydrolase
EXW26_24375	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW26_24380	COG1169	isochorismate synthase
EXW26_24385	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW26_24390	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW26_24395	COG1278	Cold shock
EXW26_24415	COG0058	SHG alpha-glucan phosphorylase activity
EXW26_24425	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW26_24430	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW26_24435	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW26_24450	COG1309	transcriptional regulator
EXW26_24585	COG1285	pathogenesis
EXW26_24590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW26_24600	COG0166	Belongs to the GPI family
EXW26_24610	COG2155	Conserved Protein
EXW26_24615	COG1098	S1 RNA binding domain
EXW26_24620	COG0436	Aminotransferase
EXW26_24625	COG1522	sequence-specific DNA binding
EXW26_24630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW26_24635	COG2267	carboxylic ester hydrolase activity
EXW26_24645	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW26_24660	COG5018	Exonuclease
EXW26_24665	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW26_24685	COG2050	protein possibly involved in aromatic compounds catabolism
EXW26_24695	COG1268	BioY protein
EXW26_24700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW26_24705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW26_24715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW26_24720	COG3584	3D domain protein
EXW26_24735	COG1252	NADH dehydrogenase
EXW26_24740	COG0492	ferredoxin-NADP+ reductase activity
EXW26_24760	COG1683	Conserved Protein
EXW26_24785	COG0316	Belongs to the HesB IscA family
EXW26_24790	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW26_24795	COG4844	belongs to the
EXW26_24800	COG1252	NADH dehydrogenase
EXW26_24810	COG0390	transport system, permease component
EXW26_24815	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW26_24850	COG4837	Protein of unknown function (DUF1462)
EXW26_24855	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW26_24865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW26_24870	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW26_24895	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW26_24905	COG0647	UMP catabolic process
EXW26_24915	COG2445	Protein of unknown function DUF86
EXW26_24920	COG1494	fructose-1,6-bisphosphatase
EXW26_24935	COG4470	Protein conserved in bacteria
EXW26_24945	COG0789	Transcriptional regulator
EXW26_24950	COG4377	Putative membrane peptidase family (DUF2324)
EXW26_24970	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW26_24975	COG0739	heme binding
EXW26_24985	COG3377	Domain of unknown function (DUF1805)
EXW26_24990	COG0737	Belongs to the 5'-nucleotidase family
EXW26_24995	COG1695	Transcriptional regulator
EXW26_25005	COG0719	Fe-S assembly protein
EXW26_25010	COG0822	iron-sulfur transferase activity
EXW26_25015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW26_25020	COG0719	Fe-S assembly protein
EXW26_25025	COG0396	ATPase activity
EXW26_25030	COG1464	Belongs to the NlpA lipoprotein family
EXW26_25035	COG1464	Belongs to the NlpA lipoprotein family
EXW26_25040	COG2011	ABC-type metal ion transport system permease component
EXW26_25045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW26_25055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW26_25060	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW26_25065	COG0509	glycine decarboxylation via glycine cleavage system
EXW26_25070	COG1393	Belongs to the ArsC family
EXW26_25115	COG1309	transcriptional regulator
EXW26_25120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_25125	COG1960	acyl-CoA dehydrogenase activity
EXW26_25130	COG0183	Belongs to the thiolase family
EXW26_25135	COG1024	Enoyl-CoA hydratase
EXW26_25135	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW26_25145	COG1686	Belongs to the peptidase S11 family
EXW26_25150	COG0506	proline dehydrogenase activity
EXW26_25160	COG0011	TIGRFAM Protein of
EXW26_25165	COG0840	transmembrane signaling receptor activity
EXW26_25180	COG2814	Major facilitator Superfamily
EXW26_25185	COG0531	amino acid
EXW26_25210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_25240	COG0586	Pfam SNARE associated Golgi protein
EXW26_25250	COG1376	ErfK ybiS ycfS ynhG family protein
EXW26_25255	COG0745	RESPONSE REGULATOR receiver
EXW26_25260	COG5002	protein histidine kinase activity
EXW26_25270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW26_25280	COG0840	transmembrane signaling receptor activity
EXW26_25285	COG0840	transmembrane signaling receptor activity
EXW26_25290	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW26_25295	COG3227	Zinc metalloprotease (Elastase)
EXW26_25300	COG1741	Belongs to the pirin family
EXW26_25315	COG0586	Pfam SNARE associated Golgi protein
EXW26_25320	COG0475	glutathione-regulated potassium exporter activity
EXW26_25325	COG0490	domain, Protein
EXW26_25330	COG1115	amino acid carrier protein
EXW26_25340	COG0783	Belongs to the Dps family
EXW26_25350	COG2318	DinB family
EXW26_25360	COG1611	Belongs to the LOG family
EXW26_25370	COG1528	Iron-storage protein
EXW26_25375	COG2311	Membrane
EXW26_25380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_25385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_25390	COG1115	amino acid carrier protein
EXW26_25395	COG1115	amino acid carrier protein
EXW26_25400	COG2910	NAD(P)H-binding
EXW26_25420	COG0656	L-ascorbic acid biosynthetic process
EXW26_25425	COG2814	Major facilitator Superfamily
EXW26_25430	COG1733	regulation of RNA biosynthetic process
EXW26_25440	COG1252	NADH dehydrogenase
EXW26_25460	COG0840	transmembrane signaling receptor activity
EXW26_25460	COG3290	protein histidine kinase activity
EXW26_25475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW26_25495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_25510	COG4224	UPF0291 protein
EXW26_25515	COG1335	isochorismatase
EXW26_25520	COG1522	sequence-specific DNA binding
EXW26_25530	COG1522	sequence-specific DNA binding
EXW26_25535	COG0288	reversible hydration of carbon dioxide
EXW26_25540	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW26_25545	COG2233	PERMEase
EXW26_25585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW26_25595	COG0557	exoribonuclease II activity
EXW26_25600	COG1647	Serine aminopeptidase, S33
EXW26_25605	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW26_25610	COG1346	cytolysis
EXW26_25625	COG0148	phosphopyruvate hydratase activity
EXW26_25635	COG0149	triose-phosphate isomerase activity
EXW26_25640	COG0126	phosphoglycerate kinase activity
EXW26_25645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW26_25660	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW26_25690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_25705	COG2323	membrane
EXW26_25720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW26_25725	COG1481	regulation of sporulation
EXW26_25730	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW26_25735	COG1660	Displays ATPase and GTPase activities
EXW26_25740	COG1051	belongs to the nudix hydrolase family
EXW26_25750	COG0492	ferredoxin-NADP+ reductase activity
EXW26_25755	COG0457	Tetratricopeptide repeat
EXW26_25760	COG0110	maltose O-acetyltransferase activity
EXW26_25765	COG0546	phosphoglycolate phosphatase activity
EXW26_25770	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW26_25775	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW26_25780	COG1950	PFAM Membrane protein of
EXW26_25785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW26_25805	COG0789	Transcriptional regulator
EXW26_25840	COG0583	DNA-binding transcription factor activity
EXW26_25845	COG0789	Transcriptional regulator
EXW26_25850	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW26_25855	COG0488	(ABC) transporter
EXW26_25865	COG1132	(ABC) transporter
EXW26_25870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW26_25875	COG0793	Belongs to the peptidase S41A family
EXW26_25875	COG3409	Peptidoglycan-binding domain 1 protein
EXW26_25880	COG2177	Part of the ABC transporter FtsEX involved in
EXW26_25885	COG2884	Cell division ATP-binding protein ftsE
EXW26_25920	COG1131	(ABC) transporter
EXW26_25955	COG1278	Cold shock
EXW26_25960	COG1040	competence protein
EXW26_25965	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW26_25970	COG1388	LysM domain
EXW26_25970	COG0791	NLP P60 protein
EXW26_25975	COG1733	regulation of RNA biosynthetic process
EXW26_25980	COG1307	EDD domain protein, DegV family
EXW26_25985	COG1739	Uncharacterized protein family UPF0029
EXW26_25990	COG1316	TRANSCRIPTIONal
EXW26_25995	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW26_26000	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW26_26005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW26_26015	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW26_26015	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW26_26035	COG1486	melibiose metabolic process
EXW26_26040	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW26_26045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW26_26055	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW26_26065	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW26_26075	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW26_26080	COG1301	dicarboxylic acid transport
EXW26_26095	COG1511	domain protein
EXW26_26100	COG0583	DNA-binding transcription factor activity
EXW26_26105	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW26_26110	COG1271	oxidase subunit
EXW26_26115	COG1294	oxidase, subunit
EXW26_26120	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW26_26125	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW26_26130	COG1620	l-lactate permease
EXW26_26140	COG2389	metal-binding protein
EXW26_26155	COG1368	sulfuric ester hydrolase activity
EXW26_26165	COG0791	NLP P60 protein
EXW26_26165	COG1388	LysM domain
EXW26_26170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_26180	COG1215	transferase activity, transferring glycosyl groups
EXW26_26185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW26_26195	COG1388	LysM domain
EXW26_26195	COG3584	3D domain protein
EXW26_26220	COG4715	Zinc finger, swim domain protein
EXW26_26225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW26_26270	COG0577	efflux transmembrane transporter activity
EXW26_26275	COG1136	(ABC) transporter
EXW26_26295	COG2271	Major facilitator Superfamily
EXW26_26310	COG3850	Histidine kinase
EXW26_26310	COG5002	protein histidine kinase activity
EXW26_26315	COG0745	RESPONSE REGULATOR receiver
EXW26_26320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW26_26335	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW26_26350	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW26_26410	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW26_26410	COG1215	transferase activity, transferring glycosyl groups
EXW26_26430	COG2244	polysaccharide biosynthetic process
EXW26_26435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW26_26440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW26_26445	COG4464	protein tyrosine phosphatase activity
EXW26_26450	COG0489	protein tyrosine kinase activity
EXW26_26455	COG3944	biosynthesis protein
EXW26_26460	COG0489	protein tyrosine kinase activity
EXW26_26475	COG1609	Transcriptional regulator
EXW26_26490	COG0739	heme binding
EXW26_26505	COG3279	Response regulator of the LytR AlgR family
EXW26_26510	COG2385	sporulation resulting in formation of a cellular spore
EXW26_26525	COG4836	Membrane
EXW26_26530	COG1007	ATP synthesis coupled electron transport
EXW26_26535	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW26_26540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW26_26545	COG0713	ATP synthesis coupled electron transport
EXW26_26550	COG0839	Belongs to the complex I subunit 6 family
EXW26_26560	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW26_26565	COG0649	NAD binding
EXW26_26570	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW26_26575	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW26_26580	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW26_26585	COG5001	Diguanylate cyclase
EXW26_26585	COG3300	MHYT domain
EXW26_26600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW26_26605	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW26_26610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW26_26615	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW26_26620	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW26_26625	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW26_26635	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW26_26660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW26_26670	COG0698	ribose 5-phosphate isomerase
EXW26_26680	COG2190	(PTS) system
EXW26_26685	COG2259	Doxx family
EXW26_26690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW26_26700	COG1971	Probably functions as a manganese efflux pump
EXW26_26705	COG0009	L-threonylcarbamoyladenylate synthase
EXW26_26720	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW26_26725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW26_26730	COG1435	thymidine kinase activity
EXW26_26740	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW26_26745	COG1494	fructose-1,6-bisphosphatase
EXW26_26765	COG4821	SIS domain
EXW26_26770	COG0504	CTP synthase activity
EXW26_26775	COG3343	RNA polymerase activity
EXW26_26785	COG1960	acyl-CoA dehydrogenase activity
EXW26_26790	COG1960	acyl-CoA dehydrogenase activity
EXW26_26795	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW26_26800	COG0183	Belongs to the thiolase family
EXW26_26805	COG0247	lactate metabolic process
EXW26_26805	COG2181	nitrate reductase activity
EXW26_26810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW26_26815	COG4294	response to UV
EXW26_26820	COG5001	Diguanylate cyclase
EXW26_26820	COG3300	MHYT domain
EXW26_26845	COG2197	response regulator
EXW26_26850	COG4585	Histidine kinase
EXW26_26855	COG0842	Transport permease protein
EXW26_26860	COG1131	(ABC) transporter
EXW26_26865	COG0024	Methionine aminopeptidase
EXW26_26875	COG2234	aminopeptidase activity
EXW26_26890	COG4506	Protein conserved in bacteria
EXW26_26895	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW26_26915	COG0010	Belongs to the arginase family
EXW26_26920	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW26_26925	COG2814	Major facilitator Superfamily
EXW26_26930	COG0789	Transcriptional regulator
EXW26_26935	COG0584	glycerophosphoryl diester phosphodiesterase
EXW26_26940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW26_26950	COG1994	Peptidase M50
EXW26_26960	COG1078	dGTPase activity
EXW26_26965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_26970	COG1120	ATPase activity
EXW26_26975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_26980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_26985	COG4844	belongs to the
EXW26_27005	COG0280	phosphate acetyltransferase
EXW26_27010	COG3253	May function as heme-dependent peroxidase
EXW26_27020	COG3773	Cell wall hydrolase
EXW26_27030	COG2363	Small membrane protein
EXW26_27045	COG2233	PERMEase
EXW26_27050	COG0561	phosphatase activity
EXW26_27055	COG2814	Major facilitator Superfamily
EXW26_27060	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW26_27065	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW26_27070	COG1131	(ABC) transporter
EXW26_27075	COG2755	lipolytic protein G-D-S-L family
EXW26_27080	COG1609	Transcriptional regulator
EXW26_27090	COG0460	homoserine dehydrogenase
EXW26_27095	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW26_27100	COG2873	o-acetylhomoserine
EXW26_27115	COG2197	response regulator
EXW26_27120	COG2203	Gaf domain
EXW26_27120	COG4585	Histidine kinase
EXW26_27125	COG0351	phosphomethylpyrimidine kinase
EXW26_27130	COG3706	GGDEF domain
EXW26_27135	COG2879	small protein
EXW26_27140	COG1966	Carbon starvation protein
EXW26_27145	COG3279	Response regulator of the LytR AlgR family
EXW26_27150	COG0477	Major facilitator Superfamily
EXW26_27180	COG0840	transmembrane signaling receptor activity
EXW26_27190	COG1607	acyl-coa hydrolase
EXW26_27200	COG1216	Glycosyl transferase, family 2
EXW26_27205	COG0488	(ABC) transporter
EXW26_27220	COG0463	Glycosyl transferase, family 2
EXW26_27225	COG1309	transcriptional regulator
EXW26_27230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW26_27235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW26_27235	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW26_27240	COG0628	permease
EXW26_27250	COG1380	Effector of murein hydrolase LrgA
EXW26_27255	COG3279	Response regulator of the LytR AlgR family
EXW26_27260	COG3275	phosphorelay sensor kinase activity
EXW26_27265	COG2814	Major facilitator Superfamily
EXW26_27270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW26_27275	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW26_27285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW26_27335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW26_27340	COG1272	protein, Hemolysin III
EXW26_27370	COG1164	Oligoendopeptidase f
EXW26_27380	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW26_27390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW26_27395	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW26_27400	COG4853	Protein conserved in bacteria
EXW26_27410	COG5002	protein histidine kinase activity
EXW26_27415	COG0745	RESPONSE REGULATOR receiver
EXW26_27445	COG0305	Participates in initiation and elongation during chromosome replication
EXW26_27450	COG0359	binds to the 23S rRNA
EXW26_27455	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW26_27460	COG4241	membrane
EXW26_27470	COG0629	single-stranded DNA binding
EXW26_27475	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW26_27480	COG0012	GTP binding
EXW26_27485	COG4481	Protein conserved in bacteria
EXW26_27490	COG0668	transmembrane transport
EXW26_27500	COG1475	DNA binding
EXW26_27505	COG1192	Involved in chromosome partitioning
EXW26_27510	COG1475	DNA binding
EXW26_27515	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW26_27520	COG0445	tRNA wobble uridine modification
EXW26_27525	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW26_27530	COG1847	R3H domain protein
EXW26_27535	COG0706	membrane insertase activity
EXW26_27540	COG0594	ribonuclease P activity
EXW26_27545	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW26_27550	COG1192	Involved in chromosome partitioning
EXW26_27570	COG0577	efflux transmembrane transporter activity
EXW26_27575	COG1136	(ABC) transporter
EXW26_27590	COG3402	PFAM membrane-flanked domain
EXW26_27675	COG1923	regulation of RNA biosynthetic process
EXW26_27690	COG2188	Transcriptional regulator
EXW26_27710	COG1674	ftsk spoiiie
EXW26_27780	COG5002	protein histidine kinase activity
EXW26_27835	COG0384	phenazine biosynthesis protein PhzF
EXW26_27845	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EXW26_27865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW26_27880	COG1674	ftsk spoiiie
EXW26_28005	COG0367	asparagine synthase
EXW26_28055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW26_28105	COG1396	sequence-specific DNA binding
EXW26_28135	COG0667	Aldo Keto reductase
EXW26_28170	COG0463	Glycosyl transferase, family 2
EXW26_28175	COG0463	Glycosyl transferase, family 2
EXW26_28180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW26_28185	COG1086	Polysaccharide biosynthesis protein
EXW26_28190	COG1088	dTDP-glucose 4,6-dehydratase activity
EXW26_28195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW26_28200	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW26_28215	COG2089	acid synthase
EXW26_28220	COG4641	Protein conserved in bacteria
EXW26_28305	COG3344	reverse transcriptase
EXW26_28315	COG0745	RESPONSE REGULATOR receiver
EXW26_28320	COG2205	protein histidine kinase activity
EXW26_28335	COG1136	(ABC) transporter
EXW26_28340	COG0577	efflux transmembrane transporter activity
EXW26_28350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW26_28350	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW26_28375	COG1136	(ABC) transporter
EXW26_28435	COG1115	amino acid carrier protein
EXW26_28445	COG1114	Component of the transport system for branched-chain amino acids
EXW26_28450	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW26_28450	COG3409	Peptidoglycan-binding domain 1 protein
EXW26_28455	COG2239	Acts as a magnesium transporter
EXW26_28460	COG0772	Belongs to the SEDS family
EXW26_28470	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW26_28485	COG0697	spore germination
EXW26_28500	COG1252	NADH dehydrogenase
EXW26_28505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_28505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_28510	COG2002	toxin-antitoxin pair type II binding
EXW26_28575	COG2814	Major facilitator Superfamily
EXW26_28600	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW26_28610	COG2002	toxin-antitoxin pair type II binding
EXW26_28645	COG0582	viral genome integration into host DNA
EXW26_28680	COG1696	Membrane protein involved in D-alanine export
EXW26_28690	COG2814	Major facilitator Superfamily
EXW26_28735	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW26_28760	COG0791	NLP P60 protein
EXW26_28760	COG1388	LysM domain
EXW26_28760	COG3103	Sh3 type 3 domain protein
EXW26_28780	COG4974	Belongs to the 'phage' integrase family
EXW26_28810	COG0083	homoserine kinase activity
EXW26_28850	COG0840	transmembrane signaling receptor activity
EXW26_28870	COG2267	carboxylic ester hydrolase activity
EXW26_28880	COG1285	pathogenesis
EXW26_28885	COG0833	amino acid
EXW26_28915	COG0745	RESPONSE REGULATOR receiver
EXW26_28930	COG5002	protein histidine kinase activity
EXW26_28935	COG0745	RESPONSE REGULATOR receiver
EXW26_28940	COG4990	cell redox homeostasis
EXW26_28950	COG0768	penicillin binding
EXW26_28965	COG0658	competence protein
EXW26_28965	COG2333	competence protein COMEC
EXW26_29020	COG2423	ornithine cyclodeaminase activity
EXW26_29030	COG2175	clavaminate synthase activity
EXW26_29035	COG0137	argininosuccinate synthase activity
EXW26_29050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW26_29055	COG0251	oxidation-reduction process
EXW26_29065	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW26_29070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW26_29075	COG1960	acyl-CoA dehydrogenase activity
EXW26_29100	COG0556	nucleotide-excision repair
EXW26_29105	COG0039	L-malate dehydrogenase activity
EXW26_29125	COG0436	Aminotransferase
EXW26_29165	COG0492	ferredoxin-NADP+ reductase activity
EXW26_29180	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EXW26_29180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW26_29190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_29195	COG1960	acyl-CoA dehydrogenase activity
EXW26_29210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW26_29220	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EXW26_29250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW26_29260	COG0438	transferase activity, transferring glycosyl groups
EXW26_29265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW26_29270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW26_29285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW26_29295	COG1131	(ABC) transporter
EXW26_29310	COG2378	regulation of single-species biofilm formation
EXW26_29350	COG2002	toxin-antitoxin pair type II binding
EXW26_29420	COG2814	Major facilitator Superfamily
EXW26_29425	COG0583	DNA-binding transcription factor activity
EXW26_29510	COG2357	RelA SpoT domain protein
EXW26_29515	COG2814	Major facilitator Superfamily
EXW26_29525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW26_29595	COG3344	reverse transcriptase
EXW26_29645	COG1725	Transcriptional regulator
EXW26_29650	COG1131	(ABC) transporter
EXW26_29690	COG1329	Transcriptional regulator
EXW26_29755	COG4176	ABC-type proline glycine betaine transport system permease component
EXW26_29760	COG4175	Glycine betaine
EXW26_29760	COG0517	IMP dehydrogenase activity
EXW26_29825	COG0156	8-amino-7-oxononanoate synthase activity
EXW26_29835	COG4974	Belongs to the 'phage' integrase family
EXW26_29845	COG1132	(ABC) transporter
EXW26_29860	COG2814	Major facilitator Superfamily
EXW26_29880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_29890	COG0582	viral genome integration into host DNA
EXW26_30010	COG0791	NLP P60 protein
EXW26_30010	COG3883	PFAM NLP P60 protein
EXW26_30115	COG1396	sequence-specific DNA binding
EXW26_30145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW26_30150	COG4974	Belongs to the 'phage' integrase family
EXW26_30155	COG0024	Methionine aminopeptidase