locus-tag	class	description
EXW60_00005	COG1876	peptidase activity
EXW60_00045	COG0741	lytic transglycosylase activity
EXW60_00120	COG1522	sequence-specific DNA binding
EXW60_00125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW60_00130	COG0657	acetylesterase activity
EXW60_00140	COG2814	Major facilitator Superfamily
EXW60_00145	COG1309	transcriptional regulator
EXW60_00180	COG0814	amino acid
EXW60_00205	COG1151	hydroxylamine reductase activity
EXW60_00240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW60_00250	COG2072	flavoprotein involved in K transport
EXW60_00295	COG1695	Transcriptional regulator
EXW60_00300	COG0604	alcohol dehydrogenase
EXW60_00305	COG1113	amino acid transport
EXW60_00315	COG2814	Major facilitator Superfamily
EXW60_00330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW60_00335	COG1012	belongs to the aldehyde dehydrogenase family
EXW60_00345	COG0534	Mate efflux family protein
EXW60_00350	COG1012	belongs to the aldehyde dehydrogenase family
EXW60_00355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW60_00370	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW60_00375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW60_00395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW60_00400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW60_00405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW60_00410	COG3739	integral membrane protein
EXW60_00430	COG0583	DNA-binding transcription factor activity
EXW60_00455	COG1193	negative regulation of DNA recombination
EXW60_00475	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW60_00480	COG1164	Oligoendopeptidase f
EXW60_00505	COG3781	membrane
EXW60_00520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW60_00585	COG0640	Transcriptional regulator
EXW60_00590	COG0604	alcohol dehydrogenase
EXW60_00595	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW60_00600	COG0457	Tetratricopeptide repeat
EXW60_00610	COG2808	Putative FMN-binding domain
EXW60_00615	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW60_00625	COG0277	FAD linked oxidase domain protein
EXW60_00645	COG1285	pathogenesis
EXW60_00655	COG2514	catechol 2,3-dioxygenase activity
EXW60_00660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW60_00665	COG1126	abc transporter atp-binding protein
EXW60_00670	COG0765	amino acid transport
EXW60_00675	COG2720	vancomycin resistance protein
EXW60_00700	COG1278	Cold shock
EXW60_00710	COG0716	FMN binding
EXW60_00720	COG0494	nUDIX hydrolase
EXW60_00740	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_00750	COG0165	Argininosuccinate lyase
EXW60_00765	COG4145	pantothenate transmembrane transporter activity
EXW60_00775	COG1012	belongs to the aldehyde dehydrogenase family
EXW60_00780	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_00790	COG1657	PFAM Prenyltransferase squalene oxidase
EXW60_00795	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW60_00800	COG2962	Rard protein
EXW60_00805	COG3326	Membrane
EXW60_00810	COG0531	amino acid
EXW60_00845	COG2226	methyltransferase
EXW60_00850	COG4166	transmembrane transport
EXW60_00855	COG4166	transmembrane transport
EXW60_00860	COG4166	transmembrane transport
EXW60_00870	COG1131	(ABC) transporter
EXW60_00890	COG0673	inositol 2-dehydrogenase activity
EXW60_00895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW60_00900	COG0187	DNA topoisomerase II activity
EXW60_00905	COG1832	CoA-binding protein
EXW60_00910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW60_00915	COG0745	RESPONSE REGULATOR receiver
EXW60_00925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW60_00925	COG1328	CTP reductase activity
EXW60_00935	COG4841	protein insertion into membrane
EXW60_00940	COG0824	Thioesterase
EXW60_00965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW60_01000	COG2274	protein secretion by the type I secretion system
EXW60_01005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW60_01035	COG2211	Major facilitator Superfamily
EXW60_01045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW60_01060	COG0183	Belongs to the thiolase family
EXW60_01065	COG0318	PFAM AMP-dependent synthetase and ligase
EXW60_01070	COG1268	BioY protein
EXW60_01075	COG0318	PFAM AMP-dependent synthetase and ligase
EXW60_01080	COG1396	sequence-specific DNA binding
EXW60_01125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW60_01140	COG5002	protein histidine kinase activity
EXW60_01150	COG0400	carboxylic ester hydrolase activity
EXW60_01155	COG0346	lactoylglutathione lyase activity
EXW60_01160	COG0069	glutamate synthase activity
EXW60_01165	COG1902	pentaerythritol trinitrate reductase activity
EXW60_01175	COG1329	Transcriptional regulator
EXW60_01180	COG0010	Belongs to the arginase family
EXW60_01190	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW60_01195	COG2986	histidine ammonia-lyase
EXW60_01205	COG2226	methyltransferase
EXW60_01235	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW60_01240	COG0785	Cytochrome C biogenesis protein
EXW60_01255	COG1473	amidohydrolase
EXW60_01260	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW60_01265	COG1131	(ABC) transporter
EXW60_01275	COG0583	DNA-binding transcription factor activity
EXW60_01285	COG1346	cytolysis
EXW60_01300	COG0730	response to heat
EXW60_01310	COG3409	Peptidoglycan-binding domain 1 protein
EXW60_01310	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW60_01330	COG1132	(ABC) transporter
EXW60_01335	COG1132	(ABC) transporter
EXW60_01340	COG3763	UPF0154 protein
EXW60_01360	COG3639	organic phosphonate transmembrane transporter activity
EXW60_01370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW60_01375	COG0737	Belongs to the 5'-nucleotidase family
EXW60_01385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW60_01390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW60_01405	COG1695	Transcriptional regulator
EXW60_01410	COG0174	glutamine synthetase
EXW60_01415	COG0789	Transcriptional regulator
EXW60_01420	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW60_01425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW60_01430	COG2860	membrane
EXW60_01435	COG0464	growth
EXW60_01455	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW60_01465	COG1388	LysM domain
EXW60_01465	COG3584	3D domain protein
EXW60_01470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW60_01470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW60_01470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW60_01475	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW60_01480	COG1349	DNA-binding transcription factor activity
EXW60_01485	COG1979	alcohol dehydrogenase
EXW60_01490	COG2322	membrane
EXW60_01500	COG1113	amino acid transport
EXW60_01515	COG1473	amidohydrolase
EXW60_01520	COG1408	metallophosphoesterase
EXW60_01525	COG2116	formate transmembrane transporter activity
EXW60_01540	COG2217	Heavy metal translocating P-type atpase
EXW60_01545	COG2608	mercury ion transmembrane transporter activity
EXW60_01550	COG1937	Protein conserved in bacteria
EXW60_01570	COG2819	hydrolase of the alpha beta superfamily
EXW60_01575	COG1120	ATPase activity
EXW60_01580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW60_01585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW60_01590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW60_01595	COG0708	Exodeoxyribonuclease III
EXW60_01600	COG2169	Transcriptional regulator
EXW60_01605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW60_01610	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW60_01615	COG2706	6-phosphogluconolactonase activity
EXW60_01620	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW60_01625	COG2364	Membrane
EXW60_01635	COG0346	lactoylglutathione lyase activity
EXW60_01640	COG5001	Diguanylate cyclase
EXW60_01640	COG3300	MHYT domain
EXW60_01680	COG1346	cytolysis
EXW60_01690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW60_01695	COG0596	Alpha beta hydrolase
EXW60_01695	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW60_01700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW60_01715	COG2188	Transcriptional regulator
EXW60_01720	COG2723	6-phospho-beta-galactosidase activity
EXW60_01730	COG3773	Cell wall hydrolase
EXW60_01740	COG1368	sulfuric ester hydrolase activity
EXW60_01745	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW60_01755	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW60_01765	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW60_01770	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW60_01780	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW60_01785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW60_01790	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW60_01795	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW60_01795	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW60_01805	COG2359	stage V sporulation protein S
EXW60_01810	COG1692	metallophosphoesterase
EXW60_01815	COG1418	mRNA catabolic process
EXW60_01820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW60_01825	COG1546	Belongs to the CinA family
EXW60_01825	COG1058	Belongs to the CinA family
EXW60_01830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW60_01835	COG1426	Protein conserved in bacteria
EXW60_01850	COG0300	oxidoreductase activity
EXW60_01855	COG0612	Peptidase, M16
EXW60_01860	COG0612	Peptidase, M16
EXW60_01865	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW60_01870	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW60_01875	COG3845	ABC transporter
EXW60_01880	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW60_01885	COG2188	Transcriptional regulator
EXW60_01890	COG1674	ftsk spoiiie
EXW60_01900	COG0740	serine-type endopeptidase activity
EXW60_01905	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW60_01915	COG0527	aspartate kinase activity
EXW60_01920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW60_01925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW60_01945	COG4824	toxin secretion phage lysis holin
EXW60_02060	COG1278	Cold shock
EXW60_02070	COG0582	viral genome integration into host DNA
EXW60_02120	COG0305	Participates in initiation and elongation during chromosome replication
EXW60_02155	COG1396	sequence-specific DNA binding
EXW60_02190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW60_02195	COG1873	PFAM PRC-barrel domain
EXW60_02200	COG0612	Peptidase, M16
EXW60_02205	COG0726	polysaccharide deacetylase
EXW60_02210	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW60_02220	COG0196	riboflavin kinase activity
EXW60_02230	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW60_02235	COG1550	Protein conserved in bacteria
EXW60_02240	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW60_02245	COG1358	cellular component organization or biogenesis
EXW60_02250	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW60_02255	COG0195	Participates in both transcription termination and antitermination
EXW60_02260	COG0779	Required for maturation of 30S ribosomal subunits
EXW60_02270	COG0442	prolyl-tRNA aminoacylation
EXW60_02275	COG0750	zinc metalloprotease
EXW60_02285	COG4589	Belongs to the CDS family
EXW60_02295	COG0233	cytoplasmic translational termination
EXW60_02300	COG0528	UMP kinase activity
EXW60_02305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW60_02310	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW60_02315	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW60_02320	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW60_02325	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW60_02330	COG4974	Belongs to the 'phage' integrase family
EXW60_02335	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW60_02340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW60_02345	COG0758	DNA mediated transformation
EXW60_02350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW60_02355	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW60_02360	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW60_02375	COG0335	large ribosomal subunit rRNA binding
EXW60_02380	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW60_02385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW60_02390	COG1837	Belongs to the UPF0109 family
EXW60_02400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW60_02405	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EXW60_02410	COG0552	protein localization to endoplasmic reticulum
EXW60_02415	COG1196	nuclear chromosome segregation
EXW60_02420	COG0571	ribonuclease III activity
EXW60_02425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW60_02430	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_02435	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW60_02440	COG0416	fatty acid biosynthetic process
EXW60_02445	COG2050	protein possibly involved in aromatic compounds catabolism
EXW60_02445	COG1349	DNA-binding transcription factor activity
EXW60_02450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW60_02455	COG1461	Dihydroxyacetone kinase
EXW60_02460	COG1302	Protein conserved in bacteria
EXW60_02475	COG1564	THIamine pyrophosphokinase
EXW60_02480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW60_02490	COG2815	serine threonine protein kinase
EXW60_02490	COG0515	serine threonine protein kinase
EXW60_02495	COG0631	protein serine/threonine phosphatase activity
EXW60_02500	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW60_02505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW60_02505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW60_02510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW60_02515	COG0242	peptide deformylase activity
EXW60_02520	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW60_02525	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW60_02530	COG1758	RNA polymerase activity
EXW60_02545	COG1561	YicC-like family, N-terminal region
EXW60_02550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW60_02565	COG0006	proline dipeptidase activity
EXW60_02585	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW60_02605	COG0167	dihydroorotate dehydrogenase activity
EXW60_02610	COG0543	2 iron, 2 sulfur cluster binding
EXW60_02615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW60_02625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW60_02630	COG0540	Belongs to the ATCase OTCase family
EXW60_02640	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW60_02645	COG0564	pseudouridine synthase activity
EXW60_02650	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW60_02660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW60_02665	COG3599	regulation of cell shape
EXW60_02670	COG2302	S4 RNA-binding domain
EXW60_02675	COG0762	integral membrane protein
EXW60_02680	COG1799	cell septum assembly
EXW60_02685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW60_02695	COG1873	PFAM PRC-barrel domain
EXW60_02700	COG1191	sigma factor activity
EXW60_02705	COG1191	sigma factor activity
EXW60_02715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW60_02720	COG0849	cell division
EXW60_02725	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW60_02740	COG0772	Belongs to the SEDS family
EXW60_02745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW60_02750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW60_02755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW60_02760	COG0768	penicillin binding
EXW60_02765	COG0768	penicillin binding
EXW60_02775	COG0275	rRNA processing
EXW60_02780	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW60_02785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW60_02790	COG0454	-acetyltransferase
EXW60_02800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW60_02805	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW60_02810	COG1323	Belongs to the UPF0348 family
EXW60_02815	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW60_02820	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW60_02825	COG3314	Sporulation integral membrane protein YlbJ
EXW60_02835	COG0742	ribosomal rna small subunit methyltransferase
EXW60_02845	COG4471	UPF0298 protein
EXW60_02850	COG3679	Belongs to the UPF0342 family
EXW60_02855	COG0406	alpha-ribazole phosphatase activity
EXW60_02870	COG2340	Cysteine-rich secretory protein family
EXW60_02880	COG3336	cytochrome c oxidase
EXW60_02905	COG0109	protoheme IX farnesyltransferase activity
EXW60_02910	COG1612	heme a metabolic process
EXW60_02915	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW60_02925	COG0772	Belongs to the SEDS family
EXW60_02930	COG4838	Belongs to the UPF0358 family
EXW60_02935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW60_02940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW60_02950	COG4896	Protein conserved in bacteria
EXW60_02965	COG1217	gtp-binding protein TYPA
EXW60_02975	COG0483	inositol monophosphate 1-phosphatase activity
EXW60_02985	COG4493	Belongs to the UPF0637 family
EXW60_02990	COG4476	Belongs to the UPF0223 family
EXW60_03000	COG1982	Orn Lys Arg decarboxylase major
EXW60_03045	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW60_03050	COG0022	dehydrogenase e1 component
EXW60_03055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW60_03070	COG0561	phosphatase activity
EXW60_03080	COG5503	Protein of unknown function (DUF1447)
EXW60_03085	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW60_03090	COG0569	domain protein
EXW60_03100	COG1473	amidohydrolase
EXW60_03105	COG2171	N-acyltransferase activity
EXW60_03110	COG0583	DNA-binding transcription factor activity
EXW60_03115	COG0517	IMP dehydrogenase activity
EXW60_03125	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW60_03135	COG4703	Protein of unknown function (DUF1797)
EXW60_03150	COG2200	EAL domain
EXW60_03155	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_03160	COG1408	metallophosphoesterase
EXW60_03205	COG2814	Major facilitator Superfamily
EXW60_03215	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW60_03225	COG3209	COG3209 Rhs family protein
EXW60_03235	COG2205	protein histidine kinase activity
EXW60_03245	COG0436	Aminotransferase
EXW60_03250	COG1609	Transcriptional regulator
EXW60_03255	COG3833	ABC-type maltose transport systems, permease component
EXW60_03260	COG1175	transmembrane transport
EXW60_03265	COG2182	Extracellular solute-binding protein
EXW60_03275	COG0366	Alpha amylase catalytic
EXW60_03280	COG3842	ATPase activity
EXW60_03320	COG0183	Belongs to the thiolase family
EXW60_03355	COG1695	Transcriptional regulator
EXW60_03360	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_03370	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW60_03375	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW60_03380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW60_03385	COG0436	Aminotransferase
EXW60_03390	COG1850	ribulose-bisphosphate carboxylase activity
EXW60_03395	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW60_03420	COG2084	Dehydrogenase
EXW60_03430	COG2199	diguanylate cyclase activity
EXW60_03435	COG0778	Nitroreductase
EXW60_03460	COG2190	(PTS) system
EXW60_03460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW60_03460	COG1263	PTS System
EXW60_03465	COG3711	transcriptional antiterminator
EXW60_03475	COG2188	Transcriptional regulator
EXW60_03480	COG0363	glucosamine-6-phosphate deaminase activity
EXW60_03485	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW60_03495	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW60_03505	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW60_03515	COG1547	Domain of unknown function (DUF309)
EXW60_03525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW60_03530	COG4086	secreted protein
EXW60_03535	COG0561	phosphatase activity
EXW60_03540	COG0697	spore germination
EXW60_03555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW60_03595	COG1686	Belongs to the peptidase S11 family
EXW60_03600	COG1725	Transcriptional regulator
EXW60_03605	COG1131	(ABC) transporter
EXW60_03630	COG1846	Transcriptional regulator
EXW60_03645	COG0598	Magnesium transport protein CorA
EXW60_03660	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW60_03670	COG4974	Belongs to the 'phage' integrase family
EXW60_03680	COG0735	belongs to the Fur family
EXW60_03685	COG1300	Membrane
EXW60_03705	COG0667	Aldo Keto reductase
EXW60_03710	COG0656	L-ascorbic acid biosynthetic process
EXW60_03715	COG0456	acetyltransferase
EXW60_03715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW60_03725	COG0737	Belongs to the 5'-nucleotidase family
EXW60_03725	COG1525	nuclease
EXW60_03725	COG4085	toxin activity
EXW60_03735	COG0596	Alpha beta hydrolase
EXW60_03740	COG2056	Na+-H+ antiporter family
EXW60_03745	COG1609	Transcriptional regulator
EXW60_03750	COG0456	acetyltransferase
EXW60_03755	COG1073	alpha beta
EXW60_03775	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW60_03775	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW60_03780	COG0307	riboflavin synthase, alpha
EXW60_03785	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW60_03785	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW60_03805	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW60_03810	COG4106	trans-aconitate 2-methyltransferase activity
EXW60_03815	COG1073	alpha beta
EXW60_03815	COG2226	methyltransferase
EXW60_03820	COG0156	8-amino-7-oxononanoate synthase activity
EXW60_03830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW60_03840	COG1757	Na H antiporter
EXW60_03845	COG0737	Belongs to the 5'-nucleotidase family
EXW60_03855	COG1522	sequence-specific DNA binding
EXW60_03885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW60_03890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW60_03900	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW60_03910	COG0300	oxidoreductase activity
EXW60_03915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW60_03920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW60_03925	COG1760	l-serine dehydratase
EXW60_03930	COG1760	l-serine dehydratase
EXW60_03940	COG1234	tRNA 3'-trailer cleavage
EXW60_03965	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW60_03970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW60_03980	COG1376	ErfK ybiS ycfS ynhG family protein
EXW60_03985	COG4129	membrane
EXW60_03990	COG1126	abc transporter atp-binding protein
EXW60_03995	COG0765	amino acid transport
EXW60_04000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW60_04010	COG2816	NAD+ diphosphatase activity
EXW60_04015	COG2323	membrane
EXW60_04020	COG0772	Belongs to the SEDS family
EXW60_04025	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW60_04030	COG0022	dehydrogenase e1 component
EXW60_04035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW60_04040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW60_04045	COG3426	butyrate kinase activity
EXW60_04055	COG0280	phosphate acetyltransferase
EXW60_04065	COG3290	protein histidine kinase activity
EXW60_04065	COG3829	transcription factor binding
EXW60_04075	COG0584	glycerophosphoryl diester phosphodiesterase
EXW60_04080	COG3093	addiction module antidote protein HigA
EXW60_04120	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW60_04165	COG0745	RESPONSE REGULATOR receiver
EXW60_04175	COG0750	zinc metalloprotease
EXW60_04180	COG0497	DNA recombination
EXW60_04185	COG1438	arginine binding
EXW60_04190	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW60_04195	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW60_04200	COG0142	geranyltranstransferase activity
EXW60_04205	COG1722	exodeoxyribonuclease VII activity
EXW60_04210	COG1570	exodeoxyribonuclease VII activity
EXW60_04215	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW60_04220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW60_04225	COG1302	Protein conserved in bacteria
EXW60_04230	COG0439	Biotin carboxylase
EXW60_04235	COG0511	ligase activity, forming carbon-carbon bonds
EXW60_04280	COG3854	ATPases associated with a variety of cellular activities
EXW60_04300	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW60_04305	COG0006	proline dipeptidase activity
EXW60_04310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW60_04320	COG3872	metal-dependent enzyme
EXW60_04330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW60_04335	COG1321	iron dependent repressor
EXW60_04365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW60_04375	COG1609	Transcriptional regulator
EXW60_04385	COG2076	Multidrug Resistance protein
EXW60_04390	COG2076	Multidrug Resistance protein
EXW60_04420	COG1131	(ABC) transporter
EXW60_04425	COG1725	Transcriptional regulator
EXW60_04440	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW60_04445	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW60_04450	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW60_04455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW60_04485	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW60_04510	COG4970	Tfp pilus assembly protein FimT
EXW60_04520	COG1459	type II secretion system
EXW60_04525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW60_04580	COG0646	methionine synthase
EXW60_04580	COG1410	methionine synthase
EXW60_04585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW60_04585	COG0646	methionine synthase
EXW60_04590	COG0626	cystathionine gamma-synthase activity
EXW60_04595	COG0626	cystathionine gamma-synthase activity
EXW60_04610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW60_04620	COG1940	carbohydrate kinase activity
EXW60_04625	COG4483	Protein conserved in bacteria
EXW60_04630	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW60_04635	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW60_04640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW60_04645	COG0704	Plays a role in the regulation of phosphate uptake
EXW60_04655	COG0581	inorganic phosphate transmembrane transporter activity
EXW60_04660	COG0573	inorganic phosphate transmembrane transporter activity
EXW60_04665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW60_04670	COG0768	penicillin binding
EXW60_04675	COG0477	Major facilitator Superfamily
EXW60_04680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW60_04700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW60_04705	COG0735	belongs to the Fur family
EXW60_04710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW60_04715	COG1121	(ABC) transporter
EXW60_04720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW60_04730	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW60_04745	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW60_04750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW60_04755	COG2384	SAM-dependent methyltransferase
EXW60_04765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW60_04770	COG0358	DNA primase activity
EXW60_04780	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW60_04785	COG0517	IMP dehydrogenase activity
EXW60_04790	COG1381	Involved in DNA repair and RecF pathway recombination
EXW60_04800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW60_04805	COG0295	cytidine deaminase activity
EXW60_04810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW60_04815	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW60_04820	COG1480	7TM receptor with intracellular HD hydrolase
EXW60_04825	COG1702	phosphate starvation-inducible protein PhoH
EXW60_04840	COG1610	YqeY-like protein
EXW60_04845	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW60_04850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW60_04855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW60_04865	COG0484	heat shock protein binding
EXW60_04870	COG0443	Heat shock 70 kDa protein
EXW60_04880	COG1420	regulation of RNA biosynthetic process
EXW60_04885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW60_04890	COG1733	regulation of RNA biosynthetic process
EXW60_04895	COG0481	GTPase activity
EXW60_04905	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW60_04910	COG0268	Binds directly to 16S ribosomal RNA
EXW60_04915	COG1466	dna polymerase III delta subunit
EXW60_04925	COG0658	competence protein
EXW60_04925	COG2333	competence protein COMEC
EXW60_04930	COG2131	deaminase
EXW60_04935	COG1555	photosystem II stabilization
EXW60_04935	COG1596	polysaccharide export
EXW60_04940	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW60_04945	COG2226	methyltransferase
EXW60_04950	COG0799	negative regulation of ribosome biogenesis
EXW60_04955	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW60_04960	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW60_04965	COG1534	Rna-binding protein
EXW60_04970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW60_04975	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW60_04980	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW60_04990	COG0688	phosphatidylethanolamine metabolic process
EXW60_05000	COG1595	DNA-templated transcription, initiation
EXW60_05005	COG2357	RelA SpoT domain protein
EXW60_05015	COG1785	Belongs to the alkaline phosphatase family
EXW60_05025	COG2267	carboxylic ester hydrolase activity
EXW60_05060	COG1404	Belongs to the peptidase S8 family
EXW60_05065	COG3186	Phenylalanine-4-hydroxylase
EXW60_05070	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW60_05075	COG2514	catechol 2,3-dioxygenase activity
EXW60_05080	COG2259	Doxx family
EXW60_05120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW60_05130	COG1012	belongs to the aldehyde dehydrogenase family
EXW60_05130	COG1454	alcohol dehydrogenase
EXW60_05135	COG0626	cystathionine gamma-synthase activity
EXW60_05140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW60_05145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW60_05150	COG2226	methyltransferase
EXW60_05165	COG0768	penicillin binding
EXW60_05170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW60_05175	COG0572	uridine kinase
EXW60_05180	COG0826	peptidase U32
EXW60_05185	COG0826	peptidase U32
EXW60_05190	COG4122	O-methyltransferase activity
EXW60_05195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW60_05205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW60_05210	COG4472	Bacterial protein of unknown function (DUF965)
EXW60_05215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW60_05225	COG0628	permease
EXW60_05245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW60_05255	COG0482	sulfurtransferase activity
EXW60_05260	COG1104	cysteine desulfurase activity
EXW60_05265	COG1959	2 iron, 2 sulfur cluster binding
EXW60_05270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW60_05280	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW60_05285	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW60_05295	COG1490	D-aminoacyl-tRNA deacylase activity
EXW60_05300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW60_05305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW60_05310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW60_05310	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW60_05315	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW60_05320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW60_05320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW60_05330	COG2244	polysaccharide biosynthetic process
EXW60_05335	COG2323	membrane
EXW60_05345	COG1862	Preprotein translocase
EXW60_05350	COG0343	queuine tRNA-ribosyltransferase activity
EXW60_05365	COG2255	four-way junction helicase activity
EXW60_05370	COG0632	four-way junction helicase activity
EXW60_05375	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW60_05400	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW60_05405	COG0157	Belongs to the NadC ModD family
EXW60_05410	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW60_05415	COG1104	cysteine desulfurase activity
EXW60_05420	COG1827	regulation of RNA biosynthetic process
EXW60_05425	COG2258	MOSC domain
EXW60_05430	COG0077	Prephenate dehydratase
EXW60_05435	COG0577	efflux transmembrane transporter activity
EXW60_05440	COG0577	efflux transmembrane transporter activity
EXW60_05445	COG1136	(ABC) transporter
EXW60_05450	COG5002	protein histidine kinase activity
EXW60_05455	COG0745	RESPONSE REGULATOR receiver
EXW60_05460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW60_05465	COG3290	protein histidine kinase activity
EXW60_05475	COG2868	ribosomal protein
EXW60_05485	COG1530	ribonuclease E activity
EXW60_05490	COG1994	Peptidase M50
EXW60_05495	COG0739	heme binding
EXW60_05500	COG2894	cell division
EXW60_05505	COG0850	regulation of cytokinetic process
EXW60_05520	COG1077	Cell shape determining protein MreB Mrl
EXW60_05525	COG2003	Belongs to the UPF0758 family
EXW60_05530	COG0424	maF-like protein
EXW60_05545	COG0285	dihydrofolate synthase activity
EXW60_05560	COG1388	LysM domain
EXW60_05565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW60_05570	COG0113	porphobilinogen synthase activity
EXW60_05575	COG1587	Uroporphyrinogen-III synthase
EXW60_05580	COG0181	hydroxymethylbilane synthase activity
EXW60_05585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW60_05590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW60_05595	COG1846	Transcriptional regulator
EXW60_05600	COG1764	response to oxidative stress
EXW60_05605	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW60_05615	COG1067	ATP-dependent peptidase activity
EXW60_05615	COG0470	DNA polymerase III
EXW60_05625	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW60_05655	COG0622	Phosphoesterase
EXW60_05665	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW60_05670	COG5401	PFAM Sporulation and spore germination
EXW60_05680	COG0477	Major facilitator Superfamily
EXW60_05690	COG1309	transcriptional regulator
EXW60_05700	COG2197	response regulator
EXW60_05705	COG2233	PERMEase
EXW60_05710	COG0402	S-adenosylhomocysteine deaminase activity
EXW60_05715	COG1983	PspC domain protein
EXW60_05720	COG1396	sequence-specific DNA binding
EXW60_05725	COG0697	spore germination
EXW60_05735	COG1959	2 iron, 2 sulfur cluster binding
EXW60_05740	COG1668	transmembrane transport
EXW60_05745	COG4152	abc transporter atp-binding protein
EXW60_05750	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW60_05755	COG1360	Flagellar Motor Protein
EXW60_05760	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW60_05770	COG1876	peptidase activity
EXW60_05775	COG0824	Thioesterase
EXW60_05780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW60_05785	COG1053	succinate dehydrogenase
EXW60_05790	COG2009	succinate dehydrogenase
EXW60_05795	COG1719	4-vinyl reductase, 4VR
EXW60_05800	COG0322	excinuclease ABC activity
EXW60_05805	COG3118	belongs to the thioredoxin family
EXW60_05810	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW60_05815	COG2086	electron transfer activity
EXW60_05820	COG1024	Enoyl-CoA hydratase
EXW60_05825	COG1309	transcriptional regulator
EXW60_05830	COG0318	PFAM AMP-dependent synthetase and ligase
EXW60_05855	COG2318	DinB family
EXW60_05880	COG1131	(ABC) transporter
EXW60_05885	COG2205	protein histidine kinase activity
EXW60_05890	COG0745	RESPONSE REGULATOR receiver
EXW60_05895	COG4895	conserved protein (DUF2196)
EXW60_05900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW60_05910	COG2329	Antibiotic biosynthesis monooxygenase
EXW60_05915	COG4509	Sortase family
EXW60_05920	COG1120	ATPase activity
EXW60_05935	COG5386	Cell surface protein
EXW60_05945	COG5386	Cell surface protein
EXW60_05950	COG1114	Component of the transport system for branched-chain amino acids
EXW60_05960	COG1193	negative regulation of DNA recombination
EXW60_05965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW60_05965	COG1796	DNA polymerase
EXW60_05970	COG1286	toxin biosynthetic process
EXW60_05975	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW60_05980	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW60_06015	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW60_06020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW60_06030	COG1418	mRNA catabolic process
EXW60_06060	COG2814	Major facilitator Superfamily
EXW60_06065	COG1566	PFAM secretion protein HlyD family protein
EXW60_06070	COG1309	transcriptional regulator
EXW60_06075	COG1363	Peptidase, m42
EXW60_06085	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW60_06100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW60_06110	COG1484	DNA-dependent DNA replication
EXW60_06115	COG3611	Membrane attachment protein
EXW60_06120	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW60_06125	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW60_06130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW60_06135	COG0237	dephospho-CoA kinase activity
EXW60_06140	COG1971	Probably functions as a manganese efflux pump
EXW60_06150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW60_06150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW60_06155	COG5002	protein histidine kinase activity
EXW60_06160	COG0745	RESPONSE REGULATOR receiver
EXW60_06175	COG0039	L-malate dehydrogenase activity
EXW60_06180	COG0538	isocitrate dehydrogenase activity
EXW60_06185	COG0372	Belongs to the citrate synthase family
EXW60_06200	COG0628	permease
EXW60_06205	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW60_06215	COG0205	6-phosphofructokinase activity
EXW60_06225	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW60_06230	COG1725	Transcriptional regulator
EXW60_06235	COG0281	malic enzyme
EXW60_06240	COG0587	DNA-directed DNA polymerase activity
EXW60_06255	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW60_06275	COG4109	DRTGG domain
EXW60_06280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW60_06285	COG0006	proline dipeptidase activity
EXW60_06310	COG0662	Cupin 2, conserved barrel domain protein
EXW60_06320	COG1476	TRANSCRIPTIONal
EXW60_06335	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_06340	COG0589	response to stress
EXW60_06355	COG0165	Argininosuccinate lyase
EXW60_06360	COG0137	argininosuccinate synthase activity
EXW60_06375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW60_06395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW60_06400	COG0827	DNA restriction-modification system
EXW60_06405	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW60_06410	COG3874	Sporulation protein YtfJ
EXW60_06425	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW60_06435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW60_06450	COG1104	cysteine desulfurase activity
EXW60_06460	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW60_06470	COG1309	transcriptional regulator
EXW60_06475	COG1956	GAF domain-containing protein
EXW60_06480	COG0626	cystathionine gamma-synthase activity
EXW60_06485	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW60_06510	COG1595	DNA-templated transcription, initiation
EXW60_06520	COG0110	maltose O-acetyltransferase activity
EXW60_06525	COG0456	acetyltransferase
EXW60_06530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW60_06535	COG0454	-acetyltransferase
EXW60_06540	COG0517	IMP dehydrogenase activity
EXW60_06545	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW60_06560	COG0745	RESPONSE REGULATOR receiver
EXW60_06565	COG5002	protein histidine kinase activity
EXW60_06570	COG0666	response to abiotic stimulus
EXW60_06580	COG1970	mechanosensitive ion channel activity
EXW60_06600	COG1609	Transcriptional regulator
EXW60_06605	COG1605	Chorismate mutase
EXW60_06605	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW60_06610	COG1605	Chorismate mutase
EXW60_06610	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW60_06615	COG4851	CamS sex pheromone cAM373 precursor
EXW60_06620	COG3118	belongs to the thioredoxin family
EXW60_06630	COG2309	aminopeptidase activity
EXW60_06650	COG0697	spore germination
EXW60_06655	COG0789	Transcriptional regulator
EXW60_06660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW60_06670	COG1674	ftsk spoiiie
EXW60_06685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW60_06690	COG4848	Belongs to the UPF0354 family
EXW60_06695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW60_06700	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW60_06705	COG1363	Peptidase, m42
EXW60_06715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW60_06720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW60_06730	COG0510	thiamine kinase activity
EXW60_06735	COG1523	belongs to the glycosyl hydrolase 13 family
EXW60_06745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW60_06750	COG1349	DNA-binding transcription factor activity
EXW60_06755	COG1187	pseudouridine synthase activity
EXW60_06760	COG2244	polysaccharide biosynthetic process
EXW60_06765	COG2081	HI0933 family
EXW60_06770	COG2814	Major facilitator Superfamily
EXW60_06780	COG3832	glyoxalase III activity
EXW60_06800	COG1329	Transcriptional regulator
EXW60_06825	COG0314	molybdopterin synthase activity
EXW60_06830	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW60_06835	COG0303	'Molybdopterin
EXW60_06840	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW60_06845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW60_06850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW60_06875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW60_06885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW60_06925	COG0495	leucyl-tRNA aminoacylation
EXW60_06930	COG2814	Major facilitator Superfamily
EXW60_06935	COG0475	glutathione-regulated potassium exporter activity
EXW60_06940	COG0490	domain, Protein
EXW60_06945	COG0582	viral genome integration into host DNA
EXW60_06960	COG1136	(ABC) transporter
EXW60_06980	COG1242	4 iron, 4 sulfur cluster binding
EXW60_06985	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW60_07005	COG2267	carboxylic ester hydrolase activity
EXW60_07010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW60_07015	COG0671	phosphoesterase, PA-phosphatase related
EXW60_07020	COG0438	transferase activity, transferring glycosyl groups
EXW60_07025	COG0746	molybdenum cofactor guanylyltransferase activity
EXW60_07030	COG0521	Mo-molybdopterin cofactor biosynthetic process
EXW60_07045	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW60_07050	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW60_07095	COG5002	protein histidine kinase activity
EXW60_07100	COG3852	Histidine kinase
EXW60_07105	COG0753	catalase activity
EXW60_07110	COG2267	carboxylic ester hydrolase activity
EXW60_07120	COG1368	sulfuric ester hydrolase activity
EXW60_07130	COG4895	conserved protein (DUF2196)
EXW60_07145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW60_07150	COG1116	anion transmembrane transporter activity
EXW60_07155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW60_07175	COG0494	nUDIX hydrolase
EXW60_07215	COG2076	Multidrug Resistance protein
EXW60_07220	COG2076	Multidrug Resistance protein
EXW60_07225	COG0789	Transcriptional regulator
EXW60_07230	COG1854	S-ribosylhomocysteine lyase activity
EXW60_07240	COG0288	reversible hydration of carbon dioxide
EXW60_07245	COG1271	oxidase subunit
EXW60_07250	COG1294	oxidase, subunit
EXW60_07275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW60_07300	COG1842	Phage shock protein A
EXW60_07325	COG3859	Proton-coupled thiamine transporter YuaJ
EXW60_07330	COG5002	protein histidine kinase activity
EXW60_07335	COG0745	RESPONSE REGULATOR receiver
EXW60_07360	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW60_07365	COG1597	lipid kinase activity
EXW60_07385	COG4977	sequence-specific DNA binding
EXW60_07395	COG0577	efflux transmembrane transporter activity
EXW60_07400	COG1136	(ABC) transporter
EXW60_07405	COG3708	Transcriptional regulator
EXW60_07405	COG2207	Transcriptional regulator
EXW60_07415	COG1131	(ABC) transporter
EXW60_07425	COG5658	integral membrane protein
EXW60_07430	COG0640	Transcriptional regulator
EXW60_07435	COG0745	RESPONSE REGULATOR receiver
EXW60_07440	COG2205	protein histidine kinase activity
EXW60_07445	COG0577	efflux transmembrane transporter activity
EXW60_07450	COG0577	efflux transmembrane transporter activity
EXW60_07455	COG1136	(ABC) transporter
EXW60_07460	COG0577	efflux transmembrane transporter activity
EXW60_07475	COG2188	Transcriptional regulator
EXW60_07495	COG3964	amidohydrolase
EXW60_07525	COG4948	Mandelate Racemase Muconate Lactonizing
EXW60_07530	COG0318	PFAM AMP-dependent synthetase and ligase
EXW60_07535	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW60_07540	COG0596	Alpha beta hydrolase
EXW60_07545	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW60_07550	COG1169	isochorismate synthase
EXW60_07555	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW60_07560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW60_07565	COG1278	Cold shock
EXW60_07575	COG0789	Transcriptional regulator
EXW60_07585	COG0058	SHG alpha-glucan phosphorylase activity
EXW60_07595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW60_07600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW60_07605	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW60_07750	COG1285	pathogenesis
EXW60_07755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW60_07765	COG0166	Belongs to the GPI family
EXW60_07775	COG2155	Conserved Protein
EXW60_07780	COG1098	S1 RNA binding domain
EXW60_07785	COG0436	Aminotransferase
EXW60_07790	COG1522	sequence-specific DNA binding
EXW60_07795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW60_07800	COG2267	carboxylic ester hydrolase activity
EXW60_07810	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW60_07825	COG5018	Exonuclease
EXW60_07830	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW60_07850	COG2050	protein possibly involved in aromatic compounds catabolism
EXW60_07860	COG1268	BioY protein
EXW60_07865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW60_07870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW60_07880	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW60_07885	COG3584	3D domain protein
EXW60_07900	COG1252	NADH dehydrogenase
EXW60_07905	COG0492	ferredoxin-NADP+ reductase activity
EXW60_07910	COG3708	Transcriptional regulator
EXW60_07925	COG1683	Conserved Protein
EXW60_07950	COG0316	Belongs to the HesB IscA family
EXW60_07955	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW60_07960	COG4844	belongs to the
EXW60_07965	COG1252	NADH dehydrogenase
EXW60_07975	COG0390	transport system, permease component
EXW60_07980	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW60_08030	COG4837	Protein of unknown function (DUF1462)
EXW60_08035	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW60_08045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW60_08050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW60_08065	COG0647	UMP catabolic process
EXW60_08075	COG2445	Protein of unknown function DUF86
EXW60_08080	COG1494	fructose-1,6-bisphosphatase
EXW60_08095	COG4470	Protein conserved in bacteria
EXW60_08105	COG0789	Transcriptional regulator
EXW60_08110	COG4377	Putative membrane peptidase family (DUF2324)
EXW60_08130	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW60_08135	COG0739	heme binding
EXW60_08145	COG3377	Domain of unknown function (DUF1805)
EXW60_08150	COG0737	Belongs to the 5'-nucleotidase family
EXW60_08155	COG1695	Transcriptional regulator
EXW60_08165	COG0719	Fe-S assembly protein
EXW60_08170	COG0822	iron-sulfur transferase activity
EXW60_08175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW60_08180	COG0719	Fe-S assembly protein
EXW60_08185	COG0396	ATPase activity
EXW60_08190	COG1464	Belongs to the NlpA lipoprotein family
EXW60_08195	COG1464	Belongs to the NlpA lipoprotein family
EXW60_08200	COG2011	ABC-type metal ion transport system permease component
EXW60_08215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW60_08220	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW60_08225	COG0509	glycine decarboxylation via glycine cleavage system
EXW60_08230	COG1393	Belongs to the ArsC family
EXW60_08295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW60_08300	COG1960	acyl-CoA dehydrogenase activity
EXW60_08305	COG0183	Belongs to the thiolase family
EXW60_08310	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW60_08310	COG1024	Enoyl-CoA hydratase
EXW60_08320	COG1686	Belongs to the peptidase S11 family
EXW60_08325	COG0506	proline dehydrogenase activity
EXW60_08335	COG0011	TIGRFAM Protein of
EXW60_08340	COG0840	transmembrane signaling receptor activity
EXW60_08355	COG2814	Major facilitator Superfamily
EXW60_08360	COG0531	amino acid
EXW60_08385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW60_08415	COG0586	Pfam SNARE associated Golgi protein
EXW60_08425	COG1376	ErfK ybiS ycfS ynhG family protein
EXW60_08430	COG0745	RESPONSE REGULATOR receiver
EXW60_08435	COG5002	protein histidine kinase activity
EXW60_08445	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW60_08455	COG0840	transmembrane signaling receptor activity
EXW60_08460	COG0840	transmembrane signaling receptor activity
EXW60_08465	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW60_08470	COG3227	Zinc metalloprotease (Elastase)
EXW60_08475	COG1741	Belongs to the pirin family
EXW60_08490	COG0586	Pfam SNARE associated Golgi protein
EXW60_08495	COG0475	glutathione-regulated potassium exporter activity
EXW60_08500	COG0490	domain, Protein
EXW60_08505	COG1115	amino acid carrier protein
EXW60_08515	COG0783	Belongs to the Dps family
EXW60_08525	COG2318	DinB family
EXW60_08535	COG1611	Belongs to the LOG family
EXW60_08545	COG1528	Iron-storage protein
EXW60_08550	COG2311	Membrane
EXW60_08555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW60_08560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW60_08565	COG1115	amino acid carrier protein
EXW60_08570	COG2910	NAD(P)H-binding
EXW60_08600	COG0656	L-ascorbic acid biosynthetic process
EXW60_08605	COG2814	Major facilitator Superfamily
EXW60_08610	COG1733	regulation of RNA biosynthetic process
EXW60_08620	COG1252	NADH dehydrogenase
EXW60_08640	COG0840	transmembrane signaling receptor activity
EXW60_08640	COG3290	protein histidine kinase activity
EXW60_08665	COG3655	Transcriptional regulator
EXW60_08680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW60_08690	COG1733	regulation of RNA biosynthetic process
EXW60_08695	COG0778	Nitroreductase
EXW60_08700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW60_08705	COG4224	UPF0291 protein
EXW60_08710	COG1522	sequence-specific DNA binding
EXW60_08715	COG0288	reversible hydration of carbon dioxide
EXW60_08720	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW60_08725	COG2233	PERMEase
EXW60_08750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW60_08770	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW60_08785	COG0557	exoribonuclease II activity
EXW60_08790	COG1647	Serine aminopeptidase, S33
EXW60_08795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW60_08800	COG1346	cytolysis
EXW60_08815	COG0148	phosphopyruvate hydratase activity
EXW60_08825	COG0149	triose-phosphate isomerase activity
EXW60_08830	COG0126	phosphoglycerate kinase activity
EXW60_08835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW60_08850	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW60_08880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW60_08895	COG2323	membrane
EXW60_08905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW60_08910	COG1481	regulation of sporulation
EXW60_08915	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW60_08920	COG1660	Displays ATPase and GTPase activities
EXW60_08925	COG1051	belongs to the nudix hydrolase family
EXW60_08935	COG0492	ferredoxin-NADP+ reductase activity
EXW60_08940	COG0457	Tetratricopeptide repeat
EXW60_08945	COG0110	maltose O-acetyltransferase activity
EXW60_08950	COG0546	phosphoglycolate phosphatase activity
EXW60_08955	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW60_08960	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW60_08965	COG1950	PFAM Membrane protein of
EXW60_08975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW60_08995	COG0789	Transcriptional regulator
EXW60_09030	COG0583	DNA-binding transcription factor activity
EXW60_09035	COG0789	Transcriptional regulator
EXW60_09040	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW60_09045	COG0488	(ABC) transporter
EXW60_09055	COG1132	(ABC) transporter
EXW60_09060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW60_09065	COG3409	Peptidoglycan-binding domain 1 protein
EXW60_09065	COG0793	Belongs to the peptidase S41A family
EXW60_09070	COG2177	Part of the ABC transporter FtsEX involved in
EXW60_09075	COG2884	Cell division ATP-binding protein ftsE
EXW60_09110	COG1131	(ABC) transporter
EXW60_09145	COG1278	Cold shock
EXW60_09150	COG1040	competence protein
EXW60_09155	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW60_09160	COG1388	LysM domain
EXW60_09160	COG0791	NLP P60 protein
EXW60_09165	COG1733	regulation of RNA biosynthetic process
EXW60_09170	COG1307	EDD domain protein, DegV family
EXW60_09175	COG1739	Uncharacterized protein family UPF0029
EXW60_09180	COG1316	TRANSCRIPTIONal
EXW60_09185	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW60_09190	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW60_09195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW60_09205	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW60_09205	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW60_09225	COG1486	melibiose metabolic process
EXW60_09230	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW60_09235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW60_09255	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW60_09265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW60_09270	COG1301	dicarboxylic acid transport
EXW60_09285	COG1511	domain protein
EXW60_09290	COG0583	DNA-binding transcription factor activity
EXW60_09295	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW60_09300	COG1271	oxidase subunit
EXW60_09305	COG1294	oxidase, subunit
EXW60_09310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW60_09315	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW60_09320	COG1620	l-lactate permease
EXW60_09330	COG2389	metal-binding protein
EXW60_09345	COG1368	sulfuric ester hydrolase activity
EXW60_09355	COG0791	NLP P60 protein
EXW60_09355	COG1388	LysM domain
EXW60_09360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW60_09370	COG1215	transferase activity, transferring glycosyl groups
EXW60_09375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW60_09385	COG3584	3D domain protein
EXW60_09385	COG1388	LysM domain
EXW60_09410	COG4715	Zinc finger, swim domain protein
EXW60_09415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW60_09455	COG0577	efflux transmembrane transporter activity
EXW60_09460	COG1136	(ABC) transporter
EXW60_09495	COG5002	protein histidine kinase activity
EXW60_09495	COG3850	Histidine kinase
EXW60_09500	COG0745	RESPONSE REGULATOR receiver
EXW60_09505	COG1316	TRANSCRIPTIONal
EXW60_09540	COG1134	teichoic acid transport
EXW60_09545	COG1682	transport, permease protein
EXW60_09550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW60_09560	COG1215	transferase activity, transferring glycosyl groups
EXW60_09575	COG0463	Glycosyl transferase, family 2
EXW60_09575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW60_09595	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EXW60_09605	COG1609	Transcriptional regulator
EXW60_09610	COG0726	polysaccharide deacetylase
EXW60_09625	COG0739	heme binding
EXW60_09640	COG3279	Response regulator of the LytR AlgR family
EXW60_09645	COG2385	sporulation resulting in formation of a cellular spore
EXW60_09660	COG4836	Membrane
EXW60_09665	COG1007	ATP synthesis coupled electron transport
EXW60_09670	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW60_09675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW60_09680	COG0713	ATP synthesis coupled electron transport
EXW60_09685	COG0839	Belongs to the complex I subunit 6 family
EXW60_09695	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW60_09700	COG0649	NAD binding
EXW60_09705	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW60_09710	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW60_09715	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW60_09720	COG5001	Diguanylate cyclase
EXW60_09720	COG3300	MHYT domain
EXW60_09735	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW60_09740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW60_09745	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW60_09750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW60_09755	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW60_09760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW60_09770	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW60_09795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW60_09805	COG0698	ribose 5-phosphate isomerase
EXW60_09815	COG2190	(PTS) system
EXW60_09820	COG2259	Doxx family
EXW60_09825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW60_09835	COG1971	Probably functions as a manganese efflux pump
EXW60_09840	COG0009	L-threonylcarbamoyladenylate synthase
EXW60_09855	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW60_09860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW60_09865	COG1435	thymidine kinase activity
EXW60_09880	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW60_09885	COG1494	fructose-1,6-bisphosphatase
EXW60_09905	COG4821	SIS domain
EXW60_09910	COG0504	CTP synthase activity
EXW60_09915	COG3343	RNA polymerase activity
EXW60_09925	COG1960	acyl-CoA dehydrogenase activity
EXW60_09930	COG1960	acyl-CoA dehydrogenase activity
EXW60_09935	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW60_09940	COG0183	Belongs to the thiolase family
EXW60_09945	COG0247	lactate metabolic process
EXW60_09945	COG2181	nitrate reductase activity
EXW60_09950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW60_09955	COG4294	response to UV
EXW60_09960	COG3300	MHYT domain
EXW60_09960	COG5001	Diguanylate cyclase
EXW60_09975	COG3227	Zinc metalloprotease (Elastase)
EXW60_09980	COG2197	response regulator
EXW60_09985	COG4585	Histidine kinase
EXW60_09990	COG0842	Transport permease protein
EXW60_09995	COG1131	(ABC) transporter
EXW60_10000	COG0024	Methionine aminopeptidase
EXW60_10010	COG2234	aminopeptidase activity
EXW60_10030	COG4506	Protein conserved in bacteria
EXW60_10035	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW60_10055	COG0010	Belongs to the arginase family
EXW60_10060	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW60_10065	COG2814	Major facilitator Superfamily
EXW60_10070	COG0789	Transcriptional regulator
EXW60_10075	COG0584	glycerophosphoryl diester phosphodiesterase
EXW60_10080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW60_10090	COG1994	Peptidase M50
EXW60_10100	COG1078	dGTPase activity
EXW60_10105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW60_10110	COG1120	ATPase activity
EXW60_10115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW60_10120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW60_10125	COG4844	belongs to the
EXW60_10140	COG0280	phosphate acetyltransferase
EXW60_10145	COG3253	May function as heme-dependent peroxidase
EXW60_10155	COG3773	Cell wall hydrolase
EXW60_10165	COG2363	Small membrane protein
EXW60_10180	COG2233	PERMEase
EXW60_10185	COG0561	phosphatase activity
EXW60_10190	COG2814	Major facilitator Superfamily
EXW60_10195	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW60_10200	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW60_10205	COG1131	(ABC) transporter
EXW60_10210	COG2755	lipolytic protein G-D-S-L family
EXW60_10215	COG1609	Transcriptional regulator
EXW60_10225	COG0460	homoserine dehydrogenase
EXW60_10230	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW60_10235	COG2873	o-acetylhomoserine
EXW60_10245	COG1011	Hydrolase
EXW60_10250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW60_10260	COG2197	response regulator
EXW60_10265	COG4585	Histidine kinase
EXW60_10265	COG2203	Gaf domain
EXW60_10270	COG0351	phosphomethylpyrimidine kinase
EXW60_10275	COG3706	GGDEF domain
EXW60_10280	COG2879	small protein
EXW60_10285	COG1966	Carbon starvation protein
EXW60_10290	COG3279	Response regulator of the LytR AlgR family
EXW60_10295	COG0477	Major facilitator Superfamily
EXW60_10320	COG0840	transmembrane signaling receptor activity
EXW60_10330	COG1607	acyl-coa hydrolase
EXW60_10335	COG1216	Glycosyl transferase, family 2
EXW60_10345	COG1216	Glycosyl transferase, family 2
EXW60_10355	COG4485	Bacterial membrane protein, YfhO
EXW60_10360	COG0463	Glycosyl transferase, family 2
EXW60_10370	COG1309	transcriptional regulator
EXW60_10375	COG0488	(ABC) transporter
EXW60_10380	COG1309	transcriptional regulator
EXW60_10385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW60_10390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW60_10390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW60_10395	COG0628	permease
EXW60_10405	COG1380	Effector of murein hydrolase LrgA
EXW60_10410	COG3279	Response regulator of the LytR AlgR family
EXW60_10415	COG3275	phosphorelay sensor kinase activity
EXW60_10420	COG2814	Major facilitator Superfamily
EXW60_10425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW60_10430	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW60_10440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW60_10495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW60_10500	COG1272	protein, Hemolysin III
EXW60_10525	COG1164	Oligoendopeptidase f
EXW60_10535	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW60_10545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW60_10550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW60_10555	COG4853	Protein conserved in bacteria
EXW60_10565	COG5002	protein histidine kinase activity
EXW60_10570	COG0745	RESPONSE REGULATOR receiver
EXW60_10600	COG0305	Participates in initiation and elongation during chromosome replication
EXW60_10605	COG0359	binds to the 23S rRNA
EXW60_10610	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW60_10615	COG4241	membrane
EXW60_10625	COG0629	single-stranded DNA binding
EXW60_10630	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW60_10635	COG0012	GTP binding
EXW60_10640	COG4481	Protein conserved in bacteria
EXW60_10645	COG0668	transmembrane transport
EXW60_10655	COG1475	DNA binding
EXW60_10660	COG1192	Involved in chromosome partitioning
EXW60_10665	COG1475	DNA binding
EXW60_10670	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW60_10675	COG0445	tRNA wobble uridine modification
EXW60_10680	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW60_10685	COG1847	R3H domain protein
EXW60_10690	COG0706	membrane insertase activity
EXW60_10695	COG0594	ribonuclease P activity
EXW60_10700	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW60_10705	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW60_10710	COG0592	DNA-directed DNA polymerase activity
EXW60_10715	COG2501	S4 domain
EXW60_10720	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW60_10725	COG0187	DNA topoisomerase II activity
EXW60_10730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW60_10765	COG0516	GMP reductase activity
EXW60_10765	COG0517	IMP dehydrogenase activity
EXW60_10770	COG1686	Belongs to the peptidase S11 family
EXW60_10775	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW60_10780	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW60_10800	COG1428	Deoxynucleoside kinase
EXW60_10805	COG1428	Deoxynucleoside kinase
EXW60_10810	COG1335	isochorismatase
EXW60_10815	COG0590	tRNA wobble adenosine to inosine editing
EXW60_10825	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW60_10830	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW60_10835	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW60_10880	COG1982	Orn Lys Arg decarboxylase major
EXW60_10885	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW60_10890	COG0470	DNA polymerase III
EXW60_10895	COG1774	PSP1 C-terminal conserved region
EXW60_10900	COG4467	Involved in initiation control of chromosome replication
EXW60_10905	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW60_10915	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW60_10920	COG2002	toxin-antitoxin pair type II binding
EXW60_10930	COG0084	hydrolase, TatD family'
EXW60_10940	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW60_10950	COG4466	Protein conserved in bacteria
EXW60_10960	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW60_10965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW60_10970	COG0251	oxidation-reduction process
EXW60_10975	COG2088	sporulation resulting in formation of a cellular spore
EXW60_10980	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW60_11000	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW60_11005	COG2002	toxin-antitoxin pair type II binding
EXW60_11010	COG2244	polysaccharide biosynthetic process
EXW60_11015	COG3956	TIGRFAM MazG family protein
EXW60_11020	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW60_11040	COG1098	S1 RNA binding domain
EXW60_11055	COG2208	phosphoserine phosphatase activity
EXW60_11065	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW60_11070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW60_11075	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW60_11080	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW60_11085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW60_11090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW60_11095	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW60_11100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW60_11105	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW60_11110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW60_11115	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW60_11120	COG1396	sequence-specific DNA binding
EXW60_11125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW60_11130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW60_11220	COG3880	PFAM UvrB UvrC protein
EXW60_11225	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW60_11230	COG0542	response to heat
EXW60_11235	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW60_11240	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW60_11245	COG4956	integral membrane protein (PIN domain superfamily)
EXW60_11250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW60_11260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW60_11265	COG1045	serine acetyltransferase
EXW60_11270	COG0215	cysteine-tRNA ligase activity
EXW60_11280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW60_11285	COG3688	RNA-binding protein containing a PIN domain
EXW60_11295	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW60_11300	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW60_11305	COG0250	Participates in transcription elongation, termination and antitermination
EXW60_11310	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW60_11315	COG0081	regulation of translation
EXW60_11320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW60_11325	COG0222	ribosome binding
EXW60_11330	COG2813	Specifically methylates the guanine in position
EXW60_11335	COG0085	RNA polymerase activity
EXW60_11340	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW60_11345	COG1358	cellular component organization or biogenesis
EXW60_11350	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW60_11355	COG0049	tRNA binding
EXW60_11360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW60_11365	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW60_11370	COG0051	transcription antitermination factor activity, RNA binding
EXW60_11375	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW60_11380	COG0088	Forms part of the polypeptide exit tunnel
EXW60_11385	COG0089	rRNA binding
EXW60_11390	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW60_11395	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW60_11400	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW60_11410	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EXW60_11415	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW60_11420	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW60_11425	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EXW60_11430	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW60_11435	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW60_11445	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW60_11455	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW60_11465	COG1841	ribosomal large subunit assembly
EXW60_11470	COG0200	Binds to the 23S rRNA
EXW60_11475	COG0201	protein transport
EXW60_11480	COG0563	adenylate kinase activity
EXW60_11485	COG0024	Methionine aminopeptidase
EXW60_11495	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW60_11500	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW60_11505	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW60_11530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW60_11540	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW60_11545	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW60_11555	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW60_11560	COG0489	protein tyrosine kinase activity
EXW60_11570	COG2194	sulfuric ester hydrolase activity
EXW60_11575	COG0726	polysaccharide deacetylase
EXW60_11655	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW60_11660	COG4856	YbbR-like protein
EXW60_11665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW60_11680	COG4946	Tricorn protease homolog
EXW60_11680	COG1506	peptidase
EXW60_11680	COG0823	Involved in the tonB-independent uptake of proteins
EXW60_11705	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_11710	COG2011	ABC-type metal ion transport system permease component
EXW60_11720	COG1464	Belongs to the NlpA lipoprotein family
EXW60_11725	COG0604	alcohol dehydrogenase
EXW60_11735	COG0277	FAD linked oxidase domain protein
EXW60_11740	COG2271	Major facilitator Superfamily
EXW60_11750	COG2814	Major facilitator Superfamily
EXW60_11765	COG0601	transmembrane transport
EXW60_11770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW60_11775	COG0444	Belongs to the ABC transporter superfamily
EXW60_11780	COG4608	Belongs to the ABC transporter superfamily
EXW60_11785	COG4166	transmembrane transport
EXW60_11795	COG2207	Transcriptional regulator
EXW60_11810	COG4166	transmembrane transport
EXW60_11815	COG4166	transmembrane transport
EXW60_11820	COG0656	L-ascorbic acid biosynthetic process
EXW60_11825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW60_11840	COG4149	molybdate abc transporter
EXW60_11845	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW60_11850	COG1910	domain protein
EXW60_11865	COG0697	spore germination
EXW60_11880	COG0204	Acyl-transferase
EXW60_11890	COG1609	Transcriptional regulator
EXW60_11900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW60_11915	COG5298	Protein conserved in bacteria
EXW60_11940	COG0488	(ABC) transporter
EXW60_11950	COG0747	negative chemotaxis
EXW60_11955	COG0747	negative chemotaxis
EXW60_11960	COG0601	transmembrane transport
EXW60_11965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW60_11970	COG0444	Belongs to the ABC transporter superfamily
EXW60_11975	COG4608	Belongs to the ABC transporter superfamily
EXW60_11980	COG0561	phosphatase activity
EXW60_12005	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW60_12010	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW60_12020	COG0531	amino acid
EXW60_12025	COG2814	Major facilitator Superfamily
EXW60_12035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW60_12045	COG4294	response to UV
EXW60_12050	COG0705	Rhomboid family
EXW60_12055	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW60_12060	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW60_12065	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW60_12070	COG0864	Transcriptional regulator
EXW60_12075	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW60_12080	COG2183	response to ionizing radiation
EXW60_12180	COG0802	atpase or kinase
EXW60_12185	COG1214	PFAM Peptidase M22, glycoprotease
EXW60_12190	COG0456	acetyltransferase
EXW60_12200	COG0488	(ABC) transporter
EXW60_12205	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW60_12215	COG1266	CAAX protease self-immunity
EXW60_12220	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW60_12225	COG0459	protein refolding
EXW60_12230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW60_12230	COG0519	Catalyzes the synthesis of GMP from XMP
EXW60_12235	COG2252	PERMEase
EXW60_12245	COG5002	protein histidine kinase activity
EXW60_12275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW60_12305	COG2226	methyltransferase
EXW60_12365	COG2205	protein histidine kinase activity
EXW60_12370	COG0745	RESPONSE REGULATOR receiver
EXW60_12390	COG0697	spore germination
EXW60_12420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW60_12425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW60_12430	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW60_12435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW60_12440	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW60_12445	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW60_12450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW60_12455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW60_12460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW60_12465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW60_12470	COG0138	bifunctional purine biosynthesis protein purh
EXW60_12475	COG0151	Belongs to the GarS family
EXW60_12500	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW60_12505	COG0210	DNA helicase
EXW60_12510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW60_12515	COG4851	CamS sex pheromone cAM373 precursor
EXW60_12525	COG1012	belongs to the aldehyde dehydrogenase family
EXW60_12530	COG1335	isochorismatase
EXW60_12540	COG2011	ABC-type metal ion transport system permease component
EXW60_12545	COG1464	Belongs to the NlpA lipoprotein family
EXW60_12560	COG0003	Pfam Anion-transporting ATPase
EXW60_12565	COG1846	Transcriptional regulator
EXW60_12570	COG4682	membrane
EXW60_12580	COG0154	amidase activity
EXW60_12585	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW60_12590	COG1597	lipid kinase activity
EXW60_12600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW60_12610	COG1012	belongs to the aldehyde dehydrogenase family
EXW60_12615	COG2076	Multidrug Resistance protein
EXW60_12620	COG2309	aminopeptidase activity
EXW60_12635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW60_12645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW60_12650	COG5002	protein histidine kinase activity
EXW60_12665	COG4807	Protein conserved in bacteria
EXW60_12690	COG1757	Na H antiporter
EXW60_12695	COG1473	amidohydrolase
EXW60_12710	COG0450	alkyl hydroperoxide reductase
EXW60_12720	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW60_12730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW60_12735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW60_12740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW60_12750	COG0492	ferredoxin-NADP+ reductase activity
EXW60_12765	COG0166	Belongs to the GPI family
EXW60_12790	COG5002	protein histidine kinase activity
EXW60_12810	COG3541	Predicted nucleotidyltransferase
EXW60_12815	COG0723	plastoquinol--plastocyanin reductase activity
EXW60_12815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW60_12825	COG0765	amino acid transport
EXW60_12830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW60_12840	COG0840	transmembrane signaling receptor activity
EXW60_12845	COG0277	FAD linked oxidase domain protein
EXW60_12850	COG0366	Alpha amylase catalytic
EXW60_12855	COG1263	PTS System
EXW60_12855	COG2190	(PTS) system
EXW60_12855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW60_12875	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW60_12880	COG0352	thiamine-phosphate diphosphorylase activity
EXW60_12885	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW60_12900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW60_12905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW60_12910	COG1116	anion transmembrane transporter activity
EXW60_12915	COG0488	(ABC) transporter
EXW60_12950	COG2270	Major facilitator Superfamily
EXW60_12980	COG2310	stress, protein
EXW60_12985	COG2310	stress, protein
EXW60_12990	COG2310	stress, protein
EXW60_12995	COG0861	Integral membrane protein TerC family
EXW60_13005	COG3853	Toxic anion resistance protein (TelA)
EXW60_13015	COG4840	Belongs to the UPF0435 family
EXW60_13020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW60_13030	COG1295	ribonuclease BN
EXW60_13035	COG2217	Heavy metal translocating P-type atpase
EXW60_13040	COG0697	spore germination
EXW60_13065	COG0586	Pfam SNARE associated Golgi protein
EXW60_13080	COG3871	stress protein (general stress protein 26)
EXW60_13085	COG0387	Pfam Sodium calcium exchanger
EXW60_13095	COG0535	radical SAM domain protein
EXW60_13115	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW60_13135	COG3829	transcription factor binding
EXW60_13145	COG0833	amino acid
EXW60_13150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW60_13170	COG2066	Belongs to the glutaminase family
EXW60_13180	COG1263	PTS System
EXW60_13180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW60_13185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW60_13200	COG1216	Glycosyl transferase, family 2
EXW60_13210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW60_13210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW60_13215	COG0463	Glycosyl transferase, family 2
EXW60_13230	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW60_13235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW60_13250	COG1228	amidohydrolase
EXW60_13255	COG1090	epimerase
EXW60_13260	COG2137	regulation of response to DNA damage stimulus
EXW60_13285	COG1988	membrane-bound metal-dependent
EXW60_13290	COG1194	a g-specific adenine glycosylase
EXW60_13310	COG3557	Belongs to the UPF0374 family
EXW60_13315	COG1132	(ABC) transporter
EXW60_13320	COG4129	membrane
EXW60_13330	COG0070	glutamate synthase
EXW60_13330	COG0069	glutamate synthase activity
EXW60_13330	COG0067	glutamate synthase
EXW60_13335	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW60_13340	COG4555	ABC transporter
EXW60_13360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW60_13365	COG0735	belongs to the Fur family
EXW60_13470	COG4974	Belongs to the 'phage' integrase family
EXW60_13555	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW60_13560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW60_13580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW60_13590	COG2766	serine protein kinase
EXW60_13595	COG2718	Belongs to the UPF0229 family
EXW60_13610	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW60_13615	COG2268	Band 7 protein
EXW60_13625	COG3290	protein histidine kinase activity
EXW60_13630	COG4565	transcriptional regulatory protein
EXW60_13635	COG2851	Citrate transporter
EXW60_13660	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW60_13665	COG3842	ATPase activity
EXW60_13670	COG1175	transmembrane transport
EXW60_13675	COG0395	ABC-type sugar transport system, permease component
EXW60_13685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW60_13690	COG0745	RESPONSE REGULATOR receiver
EXW60_13695	COG5002	protein histidine kinase activity
EXW60_13705	COG4990	cell redox homeostasis
EXW60_13715	COG3290	protein histidine kinase activity
EXW60_13720	COG4565	transcriptional regulatory protein
EXW60_13725	COG3493	citrate carrier protein
EXW60_13730	COG0281	malic enzyme
EXW60_13740	COG0697	spore germination
EXW60_13745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW60_13755	COG5002	protein histidine kinase activity
EXW60_13760	COG0745	RESPONSE REGULATOR receiver
EXW60_13765	COG0456	acetyltransferase
EXW60_13770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW60_13775	COG3383	formate dehydrogenase (NAD+) activity
EXW60_13780	COG2427	Protein of unknown function (DUF1641)
EXW60_13795	COG0531	amino acid
EXW60_13805	COG0640	Transcriptional regulator
EXW60_13810	COG2217	Heavy metal translocating P-type atpase
EXW60_13815	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW60_13825	COG3227	Zinc metalloprotease (Elastase)
EXW60_13845	COG2720	vancomycin resistance protein
EXW60_13850	COG1316	TRANSCRIPTIONal
EXW60_13855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW60_13860	COG0346	lactoylglutathione lyase activity
EXW60_13865	COG1253	flavin adenine dinucleotide binding
EXW60_13870	COG1027	Aspartate ammonia-lyase
EXW60_13875	COG1620	l-lactate permease
EXW60_13880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW60_13900	COG3104	oligopeptide transport
EXW60_13905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW60_13910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW60_13915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW60_13925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW60_13930	COG0156	8-amino-7-oxononanoate synthase activity
EXW60_13935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW60_13945	COG4548	von Willebrand factor, type A
EXW60_13950	COG0714	Associated with various cellular activities
EXW60_13970	COG0531	amino acid
EXW60_13975	COG2188	Transcriptional regulator
EXW60_13980	COG1263	PTS System
EXW60_13980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW60_13985	COG0366	Alpha amylase catalytic
EXW60_14000	COG0697	spore germination
EXW60_14005	COG4585	Histidine kinase
EXW60_14015	COG1404	Belongs to the peptidase S8 family
EXW60_14030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW60_14035	COG1115	amino acid carrier protein
EXW60_14040	COG1126	abc transporter atp-binding protein
EXW60_14045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW60_14050	COG0765	amino acid transport
EXW60_14055	COG0765	amino acid transport
EXW60_14060	COG0833	amino acid
EXW60_14085	COG2378	regulation of single-species biofilm formation
EXW60_14090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW60_14095	COG5002	protein histidine kinase activity
EXW60_14115	COG2814	Major facilitator Superfamily
EXW60_14120	COG0659	secondary active sulfate transmembrane transporter activity
EXW60_14135	COG0747	negative chemotaxis
EXW60_14145	COG0601	transmembrane transport
EXW60_14150	COG4608	Belongs to the ABC transporter superfamily
EXW60_14160	COG2271	Major facilitator Superfamily
EXW60_14165	COG1846	Transcriptional regulator
EXW60_14170	COG0477	Major facilitator Superfamily
EXW60_14175	COG1609	Transcriptional regulator
EXW60_14180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW60_14185	COG1869	D-ribose catabolic process
EXW60_14195	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW60_14200	COG1879	ABC-type sugar transport system periplasmic component
EXW60_14230	COG1063	alcohol dehydrogenase
EXW60_14245	COG3568	Endonuclease Exonuclease Phosphatase
EXW60_14275	COG0840	transmembrane signaling receptor activity
EXW60_14280	COG3583	domain protein
EXW60_14280	COG3584	3D domain protein
EXW60_14285	COG1476	TRANSCRIPTIONal
EXW60_14305	COG3104	oligopeptide transport
EXW60_14310	COG1114	Component of the transport system for branched-chain amino acids
EXW60_14325	COG1113	amino acid transport
EXW60_14330	COG2252	PERMEase
EXW60_14345	COG2153	protein acetylation
EXW60_14355	COG0475	glutathione-regulated potassium exporter activity
EXW60_14355	COG0569	domain protein
EXW60_14370	COG1845	cytochrome c oxidase, subunit III
EXW60_14375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW60_14385	COG0833	amino acid
EXW60_14390	COG4990	cell redox homeostasis
EXW60_14405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW60_14410	COG0697	spore germination
EXW60_14415	COG0531	amino acid
EXW60_14425	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW60_14430	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW60_14440	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW60_14445	COG0573	inorganic phosphate transmembrane transporter activity
EXW60_14450	COG0581	inorganic phosphate transmembrane transporter activity
EXW60_14460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW60_14580	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW60_14595	COG3103	Sh3 type 3 domain protein
EXW60_14595	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW60_14595	COG4991	sh3 domain protein
EXW60_14600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW60_14605	COG1116	anion transmembrane transporter activity
EXW60_14610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW60_14615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW60_14620	COG0352	thiamine-phosphate diphosphorylase activity
EXW60_14625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW60_14630	COG2104	thiamine diphosphate biosynthetic process
EXW60_14640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW60_14645	COG0351	phosphomethylpyrimidine kinase
EXW60_14670	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW60_14675	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW60_14680	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW60_14685	COG2205	protein histidine kinase activity
EXW60_14690	COG2814	Major facilitator Superfamily
EXW60_14695	COG1846	Transcriptional regulator
EXW60_14715	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW60_14720	COG1129	ABC transporter
EXW60_14725	COG1879	ABC-type sugar transport system periplasmic component
EXW60_14730	COG2252	PERMEase
EXW60_14735	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_14795	COG0778	Nitroreductase
EXW60_14800	COG2719	SpoVR family
EXW60_14835	COG1937	Protein conserved in bacteria
EXW60_14840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW60_14840	COG0425	Belongs to the sulfur carrier protein TusA family
EXW60_14845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW60_14845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW60_14850	COG0425	Belongs to the sulfur carrier protein TusA family
EXW60_14855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW60_14855	COG0425	Belongs to the sulfur carrier protein TusA family
EXW60_14860	COG2210	Belongs to the sulfur carrier protein TusA family
EXW60_14865	COG0730	response to heat
EXW60_14875	COG1316	TRANSCRIPTIONal
EXW60_14895	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW60_14915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW60_14915	COG3711	transcriptional antiterminator
EXW60_14920	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW60_14925	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW60_14950	COG1388	LysM domain
EXW60_14950	COG3584	3D domain protein
EXW60_14955	COG0577	efflux transmembrane transporter activity
EXW60_14960	COG1136	(ABC) transporter
EXW60_14970	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW60_14985	COG0577	efflux transmembrane transporter activity
EXW60_14990	COG1114	Component of the transport system for branched-chain amino acids
EXW60_14995	COG3546	catalase activity
EXW60_15020	COG0586	Pfam SNARE associated Golgi protein
EXW60_15055	COG0531	amino acid
EXW60_15060	COG0475	glutathione-regulated potassium exporter activity
EXW60_15070	COG1737	Transcriptional regulator
EXW60_15075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW60_15080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW60_15080	COG1263	PTS System
EXW60_15090	COG2259	Doxx family
EXW60_15110	COG0697	spore germination
EXW60_15115	COG1522	sequence-specific DNA binding
EXW60_15125	COG0300	oxidoreductase activity
EXW60_15140	COG2076	Multidrug Resistance protein
EXW60_15145	COG1309	transcriptional regulator
EXW60_15150	COG2814	Major facilitator Superfamily
EXW60_15155	COG1733	regulation of RNA biosynthetic process
EXW60_15180	COG0693	protein deglycase activity
EXW60_15190	COG0531	amino acid
EXW60_15195	COG1012	belongs to the aldehyde dehydrogenase family
EXW60_15210	COG1132	(ABC) transporter
EXW60_15215	COG1132	(ABC) transporter
EXW60_15220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW60_15225	COG0765	amino acid transport
EXW60_15230	COG1126	abc transporter atp-binding protein
EXW60_15245	COG0189	ligase activity
EXW60_15255	COG4399	Belongs to the UPF0754 family
EXW60_15260	COG3679	Belongs to the UPF0342 family
EXW60_15275	COG0028	Belongs to the TPP enzyme family
EXW60_15280	COG3527	Alpha-acetolactate decarboxylase
EXW60_15285	COG0463	Glycosyl transferase, family 2
EXW60_15290	COG1216	Glycosyl transferase, family 2
EXW60_15295	COG2094	Belongs to the DNA glycosylase MPG family
EXW60_15300	COG0561	phosphatase activity
EXW60_15310	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW60_15310	COG3409	Peptidoglycan-binding domain 1 protein
EXW60_15315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW60_15320	COG0318	PFAM AMP-dependent synthetase and ligase
EXW60_15325	COG0586	Pfam SNARE associated Golgi protein
EXW60_15335	COG0789	Transcriptional regulator
EXW60_15335	COG4978	Transcriptional regulator
EXW60_15345	COG0659	secondary active sulfate transmembrane transporter activity
EXW60_15360	COG0653	protein targeting
EXW60_15365	COG2244	polysaccharide biosynthetic process
EXW60_15375	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW60_15380	COG4196	transglutaminase domain protein
EXW60_15405	COG1024	Enoyl-CoA hydratase
EXW60_15425	COG1363	Peptidase, m42
EXW60_15440	COG2318	DinB family
EXW60_15460	COG0579	oxidoreductase
EXW60_15515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW60_15520	COG0444	Belongs to the ABC transporter superfamily
EXW60_15525	COG4608	Belongs to the ABC transporter superfamily
EXW60_15545	COG0477	Major facilitator Superfamily
EXW60_15550	COG3290	protein histidine kinase activity
EXW60_15555	COG4565	transcriptional regulatory protein
EXW60_15560	COG3181	Tripartite tricarboxylate transporter family receptor
EXW60_15585	COG2801	Transposase and inactivated derivatives
EXW60_15630	COG0305	Participates in initiation and elongation during chromosome replication
EXW60_15660	COG0477	Major facilitator Superfamily
EXW60_15700	COG2814	Major facilitator Superfamily
EXW60_15705	COG0640	Transcriptional regulator
EXW60_15740	COG2376	Dihydroxyacetone kinase
EXW60_15755	COG2376	Dihydroxyacetone kinase
EXW60_15780	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW60_15800	COG2720	vancomycin resistance protein
EXW60_15855	COG0825	malonyl-CoA metabolic process
EXW60_15875	COG3237	CsbD-like
EXW60_15895	COG2172	sigma factor antagonist activity
EXW60_15900	COG1191	sigma factor activity
EXW60_15910	COG2208	phosphoserine phosphatase activity
EXW60_15915	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW60_15920	COG0784	Response regulator, receiver
EXW60_15920	COG2205	protein histidine kinase activity
EXW60_15920	COG5002	protein histidine kinase activity
EXW60_15950	COG2807	transmembrane transport
EXW60_15965	COG4585	Histidine kinase
EXW60_15970	COG2197	response regulator
EXW60_16000	COG0420	3'-5' exonuclease activity
EXW60_16005	COG4717	serine-type aminopeptidase activity
EXW60_16010	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW60_16055	COG0346	lactoylglutathione lyase activity
EXW60_16060	COG0346	lactoylglutathione lyase activity
EXW60_16065	COG0457	Tetratricopeptide repeat
EXW60_16075	COG2267	carboxylic ester hydrolase activity
EXW60_16090	COG3620	sequence-specific DNA binding
EXW60_16110	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW60_16115	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW60_16120	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW60_16125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW60_16130	COG1695	Transcriptional regulator
EXW60_16150	COG0693	protein deglycase activity
EXW60_16155	COG1595	DNA-templated transcription, initiation
EXW60_16175	COG3973	AAA domain
EXW60_16180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW60_16195	COG1846	Transcriptional regulator
EXW60_16205	COG0537	adenosine 5'-monophosphoramidase activity
EXW60_16210	COG1131	(ABC) transporter
EXW60_16215	COG4473	ABC transporter
EXW60_16225	COG0247	lactate metabolic process
EXW60_16230	COG1139	Iron-sulfur cluster binding protein
EXW60_16235	COG1556	Lactate utilization protein
EXW60_16250	COG3402	PFAM membrane-flanked domain
EXW60_16255	COG3428	Bacterial PH domain
EXW60_16295	COG3402	PFAM membrane-flanked domain
EXW60_16300	COG3428	Bacterial PH domain
EXW60_16305	COG2329	Antibiotic biosynthesis monooxygenase
EXW60_16310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW60_16315	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW60_16320	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW60_16325	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW60_16345	COG1309	transcriptional regulator
EXW60_16350	COG1511	domain protein
EXW60_16385	COG1609	Transcriptional regulator
EXW60_16395	COG1234	tRNA 3'-trailer cleavage
EXW60_16400	COG0095	Lipoate-protein ligase
EXW60_16410	COG0318	PFAM AMP-dependent synthetase and ligase
EXW60_16425	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW60_16435	COG4208	sulfate ABC transporter
EXW60_16480	COG1408	metallophosphoesterase
EXW60_16485	COG1078	dGTPase activity
EXW60_16500	COG1595	DNA-templated transcription, initiation
EXW60_16510	COG2207	Transcriptional regulator
EXW60_16510	COG3708	Transcriptional regulator
EXW60_16515	COG2205	protein histidine kinase activity
EXW60_16520	COG0745	RESPONSE REGULATOR receiver
EXW60_16540	COG0501	Belongs to the peptidase M48B family
EXW60_16545	COG0840	transmembrane signaling receptor activity
EXW60_16550	COG0697	spore germination
EXW60_16580	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW60_16585	COG2224	Isocitrate lyase
EXW60_16595	COG1278	Cold shock
EXW60_16610	COG4903	ComK protein
EXW60_16620	COG0398	Pfam SNARE associated Golgi protein
EXW60_16630	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW60_16635	COG1074	ATP-dependent DNA helicase activity
EXW60_16685	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW60_16710	COG0367	asparagine synthase
EXW60_16720	COG0753	catalase activity
EXW60_16725	COG0004	ammonium transporteR
EXW60_16735	COG1666	GTP binding
EXW60_16740	COG2996	Protein conserved in bacteria
EXW60_16750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW60_16775	COG0561	phosphatase activity
EXW60_16795	COG2267	carboxylic ester hydrolase activity
EXW60_16810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW60_16815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW60_16820	COG5504	Zn-dependent protease
EXW60_16835	COG0180	Tryptophanyl-tRNA synthetase
EXW60_16850	COG4166	transmembrane transport
EXW60_16855	COG0601	transmembrane transport
EXW60_16860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW60_16865	COG0444	Belongs to the ABC transporter superfamily
EXW60_16870	COG4608	Belongs to the ABC transporter superfamily
EXW60_16875	COG0534	Mate efflux family protein
EXW60_16880	COG4166	transmembrane transport
EXW60_16900	COG0861	Integral membrane protein TerC family
EXW60_16905	COG4862	establishment of competence for transformation
EXW60_16910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW60_16920	COG1164	Oligoendopeptidase f
EXW60_16930	COG2346	COG2346, Truncated hemoglobins
EXW60_16935	COG4116	CYTH
EXW60_16945	COG2357	RelA SpoT domain protein
EXW60_16955	COG0564	pseudouridine synthase activity
EXW60_16965	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW60_16970	COG0772	Belongs to the SEDS family
EXW60_16975	COG1216	Glycosyl transferase, family 2
EXW60_16995	COG0457	Tetratricopeptide repeat
EXW60_16995	COG0463	Glycosyl transferase, family 2
EXW60_17015	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW60_17030	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW60_17075	COG2153	protein acetylation
EXW60_17080	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW60_17085	COG2382	esterase
EXW60_17110	COG5492	domain, Protein
EXW60_17115	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW60_17135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW60_17135	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW60_17140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW60_17145	COG0134	indole-3-glycerol-phosphate synthase activity
EXW60_17150	COG0135	phosphoribosylanthranilate isomerase activity
EXW60_17155	COG0133	tryptophan synthase activity
EXW60_17160	COG0159	tryptophan synthase activity
EXW60_17170	COG1620	l-lactate permease
EXW60_17175	COG5634	Uncharacterized conserved protein (DUF2278)
EXW60_17215	COG2226	methyltransferase
EXW60_17235	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW60_17240	COG0567	Dehydrogenase, E1 component
EXW60_17245	COG1476	TRANSCRIPTIONal
EXW60_17270	COG4152	abc transporter atp-binding protein
EXW60_17275	COG1668	transmembrane transport
EXW60_17295	COG1686	Belongs to the peptidase S11 family
EXW60_17300	COG0681	Belongs to the peptidase S26 family
EXW60_17335	COG1012	belongs to the aldehyde dehydrogenase family
EXW60_17345	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW60_17350	COG1177	transmembrane transport
EXW60_17355	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW60_17365	COG2409	Drug exporters of the RND superfamily
EXW60_17375	COG0564	pseudouridine synthase activity
EXW60_17385	COG2340	Cysteine-rich secretory protein family
EXW60_17390	COG0247	lactate metabolic process
EXW60_17395	COG0277	FAD linked oxidase domain protein
EXW60_17400	COG3835	regulator
EXW60_17410	COG0745	RESPONSE REGULATOR receiver
EXW60_17415	COG3850	Histidine kinase
EXW60_17415	COG5002	protein histidine kinase activity
EXW60_17420	COG2186	Transcriptional regulator
EXW60_17425	COG0247	lactate metabolic process
EXW60_17430	COG1139	Iron-sulfur cluster binding protein
EXW60_17435	COG1556	Lactate utilization protein
EXW60_17440	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW60_17450	COG2116	formate transmembrane transporter activity
EXW60_17455	COG0861	Integral membrane protein TerC family
EXW60_17460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW60_17470	COG2030	dehydratase
EXW60_17490	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_17495	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW60_17505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW60_17520	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW60_17525	COG3842	ATPase activity
EXW60_17535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW60_17540	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW60_17550	COG1349	DNA-binding transcription factor activity
EXW60_17560	COG0235	Class ii aldolase
EXW60_17570	COG2861	carbohydrate metabolic process
EXW60_17580	COG3852	Histidine kinase
EXW60_17585	COG1846	Transcriptional regulator
EXW60_17595	COG2318	DinB family
EXW60_17600	COG5002	protein histidine kinase activity
EXW60_17605	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW60_17610	COG0720	synthase
EXW60_17620	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW60_17625	COG4873	Protein conserved in bacteria
EXW60_17635	COG0456	acetyltransferase
EXW60_17655	COG1780	Probably involved in ribonucleotide reductase function
EXW60_17670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW60_17675	COG0531	amino acid
EXW60_17680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW60_17695	COG2204	response regulator
EXW60_17700	COG1012	belongs to the aldehyde dehydrogenase family
EXW60_17710	COG1725	Transcriptional regulator
EXW60_17715	COG1131	(ABC) transporter
EXW60_17725	COG1131	(ABC) transporter
EXW60_17730	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW60_17745	COG1522	sequence-specific DNA binding
EXW60_17755	COG1335	isochorismatase
EXW60_17765	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW60_17770	COG2070	2-Nitropropane dioxygenase
EXW60_17775	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW60_17780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW60_17785	COG1696	Membrane protein involved in D-alanine export
EXW60_17790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW60_17805	COG0716	FMN binding
EXW60_17830	COG0534	Mate efflux family protein
EXW60_17850	COG1846	Transcriptional regulator
EXW60_17865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW60_17875	COG3874	Sporulation protein YtfJ
EXW60_17895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW60_17900	COG0028	Belongs to the TPP enzyme family
EXW60_17905	COG0440	acetolactate synthase activity
EXW60_17915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW60_17925	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW60_17935	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW60_17940	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW60_17950	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW60_17955	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW60_17960	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW60_17965	COG0107	imidazoleglycerol-phosphate synthase activity
EXW60_17975	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW60_17980	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW60_17995	COG1183	phosphatidylcholine synthase activity
EXW60_18000	COG1368	sulfuric ester hydrolase activity
EXW60_18010	COG0019	diaminopimelate decarboxylase activity
EXW60_18020	COG0175	sulfate reduction
EXW60_18025	COG2046	Belongs to the sulfate adenylyltransferase family
EXW60_18030	COG0529	Catalyzes the synthesis of activated sulfate
EXW60_18035	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW60_18055	COG1648	precorrin-2 dehydrogenase activity
EXW60_18060	COG0733	neurotransmitter:sodium symporter activity
EXW60_18080	COG1757	Na H antiporter
EXW60_18100	COG4758	membrane
EXW60_18105	COG4585	Histidine kinase
EXW60_18110	COG2197	response regulator
EXW60_18120	COG1114	Component of the transport system for branched-chain amino acids
EXW60_18130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW60_18175	COG0730	response to heat
EXW60_18180	COG0306	phosphate transporter
EXW60_18185	COG1392	Phosphate transport regulator
EXW60_18190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW60_18205	COG3852	Histidine kinase
EXW60_18210	COG1801	Protein of unknown function DUF72
EXW60_18220	COG0582	viral genome integration into host DNA
EXW60_18225	COG5002	protein histidine kinase activity
EXW60_18240	COG0392	lysyltransferase activity
EXW60_18240	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW60_18255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW60_18260	COG1686	Belongs to the peptidase S11 family
EXW60_18265	COG2715	membrane protein required for spore maturation
EXW60_18270	COG0700	Nucleoside recognition
EXW60_18275	COG1187	pseudouridine synthase activity
EXW60_18285	COG1333	cytochrome c biogenesis protein
EXW60_18290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW60_18295	COG0745	RESPONSE REGULATOR receiver
EXW60_18300	COG5002	protein histidine kinase activity
EXW60_18305	COG2096	Adenosyltransferase
EXW60_18310	COG4942	peptidase
EXW60_18320	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW60_18325	COG1141	Ferredoxin
EXW60_18335	COG4955	Helix-turn-helix domain
EXW60_18340	COG0514	ATP-dependent DNA helicase (RecQ)
EXW60_18345	COG1266	CAAX protease self-immunity
EXW60_18355	COG1408	metallophosphoesterase
EXW60_18370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW60_18390	COG0492	ferredoxin-NADP+ reductase activity
EXW60_18395	COG0252	asparaginase activity
EXW60_18400	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW60_18410	COG1304	FMN binding
EXW60_18440	COG1160	GTP binding
EXW60_18445	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW60_18465	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW60_18475	COG0302	gtp cyclohydrolase
EXW60_18480	COG0142	geranyltranstransferase activity
EXW60_18485	COG2226	methyltransferase
EXW60_18490	COG0142	geranyltranstransferase activity
EXW60_18505	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW60_18515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW60_18520	COG0457	Tetratricopeptide repeat
EXW60_18525	COG5582	Belongs to the UPF0302 family
EXW60_18540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW60_18555	COG4347	Protein of unknown function (DUF1405)
EXW60_18570	COG2738	Putative neutral zinc metallopeptidase
EXW60_18580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW60_18590	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW60_18595	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW60_18600	COG1803	Methylglyoxal synthase
EXW60_18605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW60_18610	COG0438	transferase activity, transferring glycosyl groups
EXW60_18615	COG0617	tRNA 3'-terminal CCA addition
EXW60_18625	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW60_18630	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW60_18640	COG1199	ATP-dependent helicase activity
EXW60_18640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW60_18660	COG3935	DnaD domain protein
EXW60_18665	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW60_18675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW60_18675	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW60_18680	COG3331	DNA recombination
EXW60_18715	COG4474	Belongs to the UPF0398 family
EXW60_18720	COG3599	regulation of cell shape
EXW60_18730	COG0116	Belongs to the methyltransferase superfamily
EXW60_18740	COG1199	ATP-dependent helicase activity
EXW60_18745	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW60_18755	COG0024	Methionine aminopeptidase
EXW60_18765	COG2233	PERMEase
EXW60_18770	COG2311	Membrane
EXW60_18775	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW60_18785	COG0456	acetyltransferase
EXW60_18795	COG2897	thiosulfate sulfurtransferase activity
EXW60_18835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW60_18875	COG1215	transferase activity, transferring glycosyl groups
EXW60_18880	COG0438	transferase activity, transferring glycosyl groups
EXW60_18895	COG0454	-acetyltransferase
EXW60_18915	COG0328	RNA-DNA hybrid ribonuclease activity
EXW60_18950	COG3403	YqcI/YcgG family
EXW60_18955	COG1280	lysine exporter protein (LysE YggA)
EXW60_18970	COG3162	membrane
EXW60_18980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW60_18990	COG0475	glutathione-regulated potassium exporter activity
EXW60_18995	COG0789	Transcriptional regulator
EXW60_18995	COG4978	Transcriptional regulator
EXW60_19005	COG2323	membrane
EXW60_19010	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW60_19055	COG1923	regulation of RNA biosynthetic process
EXW60_19065	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW60_19070	COG1360	Flagellar Motor Protein
EXW60_19075	COG2201	protein-glutamate methylesterase activity
EXW60_19080	COG2198	Histidine kinase
EXW60_19080	COG0643	Histidine kinase
EXW60_19085	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW60_19085	COG1776	CheC inhibitor of MCP methylation
EXW60_19100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW60_19120	COG1256	bacterial-type flagellum assembly
EXW60_19125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW60_19150	COG1815	bacterial-type flagellum-dependent cell motility
EXW60_19155	COG1558	bacterial-type flagellum-dependent cell motility
EXW60_19165	COG1766	The M ring may be actively involved in energy transduction
EXW60_19170	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW60_19180	COG1157	protein secretion by the type III secretion system
EXW60_19200	COG1749	Flagellar hook protein flgE
EXW60_19215	COG0835	chemotaxis
EXW60_19215	COG0784	Response regulator, receiver
EXW60_19240	COG0861	Integral membrane protein TerC family
EXW60_19250	COG3383	formate dehydrogenase (NAD+) activity
EXW60_19255	COG2427	Protein of unknown function (DUF1641)
EXW60_19260	COG5609	conserved protein (DUF2294)
EXW60_19265	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW60_19275	COG2116	formate transmembrane transporter activity
EXW60_19280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW60_19285	COG0303	'Molybdopterin
EXW60_19290	COG0314	molybdopterin synthase activity
EXW60_19295	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW60_19305	COG0489	protein tyrosine kinase activity
EXW60_19310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW60_19315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW60_19320	COG0741	lytic transglycosylase activity
EXW60_19330	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW60_19335	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW60_19335	COG1776	CheC inhibitor of MCP methylation
EXW60_19345	COG1338	Plays a role in the flagellum-specific transport system
EXW60_19350	COG1987	bacterial-type flagellum assembly
EXW60_19360	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW60_19365	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW60_19370	COG1419	protein localization to endoplasmic reticulum
EXW60_19375	COG4786	Flagellar basal body rod
EXW60_19380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW60_19420	COG2329	Antibiotic biosynthesis monooxygenase
EXW60_19435	COG2814	Major facilitator Superfamily
EXW60_19445	COG0583	DNA-binding transcription factor activity
EXW60_19450	COG3842	ATPase activity
EXW60_19500	COG0406	alpha-ribazole phosphatase activity
EXW60_19530	COG0367	asparagine synthase
EXW60_19560	COG1802	Transcriptional regulator
EXW60_19565	COG0697	spore germination
EXW60_19580	COG0438	transferase activity, transferring glycosyl groups
EXW60_19580	COG1216	Glycosyl transferase, family 2
EXW60_19585	COG1757	Na H antiporter
EXW60_19605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW60_19625	COG0534	Mate efflux family protein
EXW60_19630	COG3340	Belongs to the peptidase S51 family
EXW60_19650	COG0785	Cytochrome C biogenesis protein
EXW60_19655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW60_19670	COG3048	D-serine ammonia-lyase activity
EXW60_19675	COG2733	membrane
EXW60_19715	COG1131	(ABC) transporter
EXW60_19730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW60_19735	COG0528	UMP kinase activity
EXW60_19745	COG1027	Aspartate ammonia-lyase
EXW60_19750	COG0281	malic enzyme
EXW60_19755	COG4191	Histidine kinase
EXW60_19760	COG0784	Response regulator, receiver
EXW60_19765	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW60_19780	COG2502	aspartate--ammonia ligase
EXW60_19785	COG3620	sequence-specific DNA binding
EXW60_19820	COG1051	belongs to the nudix hydrolase family
EXW60_19825	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW60_19835	COG2814	Major facilitator Superfamily
EXW60_19860	COG1695	Transcriptional regulator
EXW60_19875	COG0477	Major facilitator Superfamily
EXW60_19890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW60_19895	COG2223	nitrite transmembrane transporter activity
EXW60_19900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW60_19915	COG2244	polysaccharide biosynthetic process
EXW60_19920	COG0733	neurotransmitter:sodium symporter activity
EXW60_19930	COG5566	PFAM Mor transcription activator
EXW60_19935	COG2323	membrane
EXW60_19955	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW60_19960	COG2132	Multicopper oxidase
EXW60_19970	COG5002	protein histidine kinase activity
EXW60_19975	COG0745	RESPONSE REGULATOR receiver
EXW60_19985	COG0129	dihydroxy-acid dehydratase activity
EXW60_19990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW60_20015	COG2814	Major facilitator Superfamily
EXW60_20020	COG3384	dioxygenase
EXW60_20060	COG4166	transmembrane transport
EXW60_20065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW60_20085	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW60_20090	COG1054	Belongs to the UPF0176 family
EXW60_20100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW60_20105	COG0531	amino acid
EXW60_20130	COG2390	Transcriptional regulator
EXW60_20140	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW60_20145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW60_20150	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW60_20155	COG0295	cytidine deaminase activity
EXW60_20165	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW60_20185	COG0583	DNA-binding transcription factor activity
EXW60_20210	COG2132	Multicopper oxidase
EXW60_20220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW60_20230	COG0583	DNA-binding transcription factor activity
EXW60_20250	COG1114	Component of the transport system for branched-chain amino acids
EXW60_20270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW60_20280	COG1276	copper resistance
EXW60_20280	COG2372	response to copper ion
EXW60_20285	COG4549	nuclear export factor GLE1
EXW60_20295	COG0697	spore germination
EXW60_20300	COG0583	DNA-binding transcription factor activity
EXW60_20305	COG1959	2 iron, 2 sulfur cluster binding
EXW60_20310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW60_20315	COG0778	Nitroreductase
EXW60_20325	COG0628	permease
EXW60_20340	COG1231	oxidoreductase activity
EXW60_20345	COG0523	cobalamin synthesis protein
EXW60_20355	COG0411	ABC transporter
EXW60_20375	COG0583	DNA-binding transcription factor activity
EXW60_20385	COG1942	4-Oxalocrotonate Tautomerase
EXW60_20400	COG0346	lactoylglutathione lyase activity
EXW60_20410	COG1271	oxidase subunit
EXW60_20415	COG1294	oxidase, subunit
EXW60_20420	COG4988	ABC transporter
EXW60_20425	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW60_20455	COG1686	Belongs to the peptidase S11 family
EXW60_20470	COG0791	NLP P60 protein
EXW60_20470	COG1388	LysM domain
EXW60_20480	COG1132	(ABC) transporter
EXW60_20485	COG0745	RESPONSE REGULATOR receiver
EXW60_20490	COG5002	protein histidine kinase activity
EXW60_20495	COG0300	oxidoreductase activity
EXW60_20500	COG4122	O-methyltransferase activity
EXW60_20530	COG0460	homoserine dehydrogenase
EXW60_20540	COG0083	homoserine kinase activity
EXW60_20555	COG1316	TRANSCRIPTIONal
EXW60_20570	COG1285	pathogenesis
EXW60_20575	COG1247	-acetyltransferase
EXW60_20595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW60_20605	COG1082	Xylose isomerase domain protein TIM barrel
EXW60_20615	COG2814	Major facilitator Superfamily
EXW60_20620	COG1279	arginine transmembrane transporter activity
EXW60_20625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW60_20635	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW60_20665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW60_20670	COG0577	efflux transmembrane transporter activity
EXW60_20675	COG2002	toxin-antitoxin pair type II binding
EXW60_20680	COG1404	Belongs to the peptidase S8 family
EXW60_20685	COG0640	Transcriptional regulator
EXW60_20690	COG0667	Aldo Keto reductase
EXW60_20695	COG2814	Major facilitator Superfamily
EXW60_20735	COG3949	Membrane
EXW60_20740	COG0783	Belongs to the Dps family
EXW60_20755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW60_20765	COG1231	oxidoreductase activity
EXW60_20770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW60_20775	COG4989	oxidoreductase activity
EXW60_20780	COG0523	cobalamin synthesis protein
EXW60_20785	COG0456	acetyltransferase
EXW60_20790	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW60_20815	COG1136	(ABC) transporter
EXW60_20820	COG0577	efflux transmembrane transporter activity
EXW60_20835	COG1902	pentaerythritol trinitrate reductase activity
EXW60_20840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW60_20850	COG4166	transmembrane transport
EXW60_20855	COG0346	lactoylglutathione lyase activity
EXW60_20865	COG0406	alpha-ribazole phosphatase activity
EXW60_20875	COG5337	Spore coat protein CotH
EXW60_20880	COG1051	belongs to the nudix hydrolase family
EXW60_20885	COG0586	Pfam SNARE associated Golgi protein
EXW60_20890	COG2244	polysaccharide biosynthetic process
EXW60_20900	COG0701	Predicted permease
EXW60_20905	COG3689	TIGRFAM TIGR03943 family protein
EXW60_20910	COG1607	acyl-coa hydrolase
EXW60_20920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW60_20935	COG0702	epimerase
EXW60_20940	COG2839	Protein conserved in bacteria
EXW60_20945	COG1253	flavin adenine dinucleotide binding
EXW60_20970	COG1114	Component of the transport system for branched-chain amino acids
EXW60_20975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW60_20995	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW60_21010	COG1876	peptidase activity
EXW60_21015	COG0494	nUDIX hydrolase
EXW60_21040	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW60_21050	COG0561	phosphatase activity
EXW60_21055	COG1846	Transcriptional regulator
EXW60_21060	COG2814	Major facilitator Superfamily
EXW60_21070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW60_21075	COG4106	trans-aconitate 2-methyltransferase activity
EXW60_21090	COG1819	glycosyl
EXW60_21095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW60_21100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW60_21125	COG0456	acetyltransferase
EXW60_21170	COG4974	Belongs to the 'phage' integrase family
EXW60_21270	COG3874	Sporulation protein YtfJ
EXW60_21295	COG2226	methyltransferase
EXW60_21325	COG0604	alcohol dehydrogenase
EXW60_21330	COG1595	DNA-templated transcription, initiation
EXW60_21355	COG0426	domain, Protein
EXW60_21355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW60_21365	COG0386	Belongs to the glutathione peroxidase family
EXW60_21370	COG1305	Transglutaminase-like
EXW60_21375	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW60_21380	COG0714	Associated with various cellular activities
EXW60_21385	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW60_21390	COG1140	nitrate reductase beta subunit
EXW60_21395	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW60_21400	COG2181	nitrate reductase activity
EXW60_21405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW60_21410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW60_21415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW60_21420	COG0303	'Molybdopterin
EXW60_21425	COG0314	molybdopterin synthase activity
EXW60_21435	COG2223	nitrite transmembrane transporter activity
EXW60_21455	COG1648	precorrin-2 dehydrogenase activity
EXW60_21465	COG1587	Uroporphyrinogen-III synthase
EXW60_21465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW60_21470	COG2146	nitrite reductase [NAD(P)H] activity
EXW60_21475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW60_21480	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW60_21510	COG2359	stage V sporulation protein S
EXW60_21520	COG1418	mRNA catabolic process
EXW60_21525	COG0488	(ABC) transporter
EXW60_21555	COG1413	lyase activity
EXW60_21570	COG2136	Putative SAM-dependent methyltransferase
EXW60_21570	COG2521	methyltransferase
EXW60_21575	COG0018	arginyl-trna synthetase
EXW60_21625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW60_21635	COG0017	Asparaginyl-tRNA synthetase
EXW60_21640	COG0733	neurotransmitter:sodium symporter activity
EXW60_21670	COG2610	gluconate transmembrane transporter activity
EXW60_21680	COG1794	racemase activity, acting on amino acids and derivatives
EXW60_21690	COG0456	acetyltransferase
EXW60_21695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW60_21700	COG1131	(ABC) transporter
EXW60_21705	COG4473	ABC transporter
EXW60_21715	COG0546	phosphoglycolate phosphatase activity
EXW60_21765	COG0768	penicillin binding
EXW60_21780	COG1272	protein, Hemolysin III
EXW60_21785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW60_21790	COG0805	protein transport
EXW60_21800	COG1307	EDD domain protein, DegV family
EXW60_21805	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW60_21810	COG1999	signal sequence binding
EXW60_21815	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW60_21820	COG0367	asparagine synthase
EXW60_21835	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW60_21840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW60_21845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW60_21865	COG1335	isochorismatase
EXW60_21875	COG0668	transmembrane transport
EXW60_21880	COG2203	Gaf domain
EXW60_21880	COG4585	Histidine kinase
EXW60_21885	COG2197	response regulator
EXW60_21890	COG1737	Transcriptional regulator
EXW60_21895	COG1064	alcohol dehydrogenase
EXW60_21915	COG1070	Carbohydrate kinase
EXW60_21925	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW60_21945	COG1125	glycine betaine transport
EXW60_21945	COG0517	IMP dehydrogenase activity
EXW60_21950	COG1174	glycine betaine transport
EXW60_21985	COG1253	flavin adenine dinucleotide binding
EXW60_21990	COG1012	belongs to the aldehyde dehydrogenase family
EXW60_21995	COG5506	Protein of unknown function (DUF1694)
EXW60_22010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW60_22015	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW60_22020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW60_22025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW60_22030	COG0456	acetyltransferase
EXW60_22035	COG3829	transcription factor binding
EXW60_22040	COG1509	lysine 2,3-aminomutase activity
EXW60_22050	COG4479	Belongs to the UPF0346 family
EXW60_22075	COG4991	sh3 domain protein
EXW60_22075	COG3064	Membrane
EXW60_22075	COG0515	serine threonine protein kinase
EXW60_22085	COG0671	phosphoesterase, PA-phosphatase related
EXW60_22090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW60_22095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW60_22170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW60_22195	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_22215	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW60_22215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW60_22225	COG2814	Major facilitator Superfamily
EXW60_22235	COG0372	Belongs to the citrate synthase family
EXW60_22240	COG2079	MmgE PrpD family protein
EXW60_22245	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW60_22250	COG1960	acyl-CoA dehydrogenase activity
EXW60_22255	COG2084	Dehydrogenase
EXW60_22260	COG1012	belongs to the aldehyde dehydrogenase family
EXW60_22265	COG1280	lysine exporter protein (LysE YggA)
EXW60_22270	COG1024	Enoyl-CoA hydratase
EXW60_22285	COG0420	3'-5' exonuclease activity
EXW60_22305	COG2223	nitrite transmembrane transporter activity
EXW60_22310	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_22315	COG1169	isochorismate synthase
EXW60_22320	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW60_22325	COG3433	isochorismatase activity
EXW60_22325	COG1535	isochorismatase
EXW60_22330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW60_22335	COG3251	PFAM MbtH domain protein
EXW60_22340	COG2814	Major facilitator Superfamily
EXW60_22355	COG0776	regulation of translation
EXW60_22365	COG2318	DinB family
EXW60_22370	COG1115	amino acid carrier protein
EXW60_22385	COG2329	Antibiotic biosynthesis monooxygenase
EXW60_22400	COG1187	pseudouridine synthase activity
EXW60_22405	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW60_22410	COG3655	Transcriptional regulator
EXW60_22420	COG1136	(ABC) transporter
EXW60_22430	COG2814	Major facilitator Superfamily
EXW60_22445	COG0028	Belongs to the TPP enzyme family
EXW60_22470	COG1253	flavin adenine dinucleotide binding
EXW60_22505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW60_22525	COG1846	Transcriptional regulator
EXW60_22540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW60_22545	COG1309	transcriptional regulator
EXW60_22575	COG1247	-acetyltransferase
EXW60_22595	COG1132	(ABC) transporter
EXW60_22605	COG1309	transcriptional regulator
EXW60_22610	COG2357	RelA SpoT domain protein
EXW60_22615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW60_22650	COG0596	Alpha beta hydrolase
EXW60_22655	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW60_22665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW60_22695	COG0583	DNA-binding transcription factor activity
EXW60_22700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW60_22760	COG0583	DNA-binding transcription factor activity
EXW60_22765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW60_22770	COG2258	MOSC domain
EXW60_22785	COG1132	(ABC) transporter
EXW60_22790	COG1132	(ABC) transporter
EXW60_22800	COG1396	sequence-specific DNA binding
EXW60_22825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW60_22835	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW60_22840	COG1595	DNA-templated transcription, initiation
EXW60_22860	COG1649	PFAM Uncharacterised BCR, COG1649
EXW60_22880	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW60_22885	COG2971	BadF BadG BcrA BcrD
EXW60_22950	COG1309	transcriptional regulator
EXW60_22965	COG0577	efflux transmembrane transporter activity
EXW60_22965	COG1136	(ABC) transporter
EXW60_22970	COG0500	methyltransferase
EXW60_22970	COG3615	Tellurite resistance protein tehB
EXW60_22985	COG0588	phosphoglycerate mutase activity
EXW60_23005	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW60_23010	COG0110	maltose O-acetyltransferase activity
EXW60_23025	COG1136	(ABC) transporter
EXW60_23055	COG1686	Belongs to the peptidase S11 family
EXW60_23080	COG0768	penicillin binding
EXW60_23085	COG0745	RESPONSE REGULATOR receiver
EXW60_23090	COG2205	protein histidine kinase activity
EXW60_23095	COG1136	(ABC) transporter
EXW60_23100	COG0577	efflux transmembrane transporter activity
EXW60_23110	COG1595	DNA-templated transcription, initiation
EXW60_23120	COG0768	penicillin binding
EXW60_23125	COG0768	penicillin binding
EXW60_23160	COG1252	NADH dehydrogenase
EXW60_23165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW60_23165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW60_23210	COG3397	chitin binding
EXW60_23215	COG0823	Involved in the tonB-independent uptake of proteins
EXW60_23225	COG1408	metallophosphoesterase
EXW60_23235	COG1131	(ABC) transporter
EXW60_23245	COG1309	transcriptional regulator
EXW60_23255	COG1960	acyl-CoA dehydrogenase activity
EXW60_23260	COG0439	Biotin carboxylase
EXW60_23265	COG0511	ligase activity, forming carbon-carbon bonds
EXW60_23270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW60_23275	COG1024	Enoyl-CoA hydratase
EXW60_23280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW60_23285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW60_23325	COG0572	uridine kinase
EXW60_23360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW60_23390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW60_23415	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_23420	COG1733	regulation of RNA biosynthetic process
EXW60_23445	COG1309	transcriptional regulator
EXW60_23475	COG0697	spore germination
EXW60_23480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW60_23510	COG2323	membrane
EXW60_23515	COG2132	Multicopper oxidase
EXW60_23530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW60_23535	COG0697	spore germination
EXW60_23540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW60_23545	COG0201	protein transport
EXW60_23555	COG0737	Belongs to the 5'-nucleotidase family
EXW60_23560	COG3227	Zinc metalloprotease (Elastase)
EXW60_23565	COG1523	belongs to the glycosyl hydrolase 13 family
EXW60_23580	COG0076	glutamate decarboxylase activity
EXW60_23585	COG0657	acetylesterase activity
EXW60_23605	COG0577	efflux transmembrane transporter activity
EXW60_23610	COG1136	(ABC) transporter
EXW60_23630	COG0745	RESPONSE REGULATOR receiver
EXW60_23660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW60_23665	COG1183	phosphatidylcholine synthase activity
EXW60_23675	COG1132	(ABC) transporter
EXW60_23680	COG3961	Belongs to the TPP enzyme family
EXW60_23700	COG0322	excinuclease ABC activity
EXW60_23725	COG2318	DinB family
EXW60_23740	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW60_23800	COG0592	DNA-directed DNA polymerase activity
EXW60_23805	COG2816	NAD+ diphosphatase activity
EXW60_23815	COG2223	nitrite transmembrane transporter activity
EXW60_23820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW60_23830	COG0494	nUDIX hydrolase
EXW60_23850	COG0697	spore germination
EXW60_23855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW60_23880	COG1733	regulation of RNA biosynthetic process
EXW60_23905	COG2375	cellular response to nickel ion
EXW60_23905	COG1132	(ABC) transporter
EXW60_23910	COG1132	(ABC) transporter
EXW60_23945	COG0768	penicillin binding
EXW60_23950	COG0671	phosphoesterase, PA-phosphatase related
EXW60_23955	COG0604	alcohol dehydrogenase
EXW60_23960	COG5002	protein histidine kinase activity
EXW60_23965	COG0745	RESPONSE REGULATOR receiver
EXW60_24000	COG1122	ATPase activity
EXW60_24005	COG4720	Psort location CytoplasmicMembrane, score
EXW60_24025	COG0768	penicillin binding
EXW60_24035	COG0561	phosphatase activity
EXW60_24085	COG2124	cytochrome p450
EXW60_24135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW60_24145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW60_24150	COG0460	homoserine dehydrogenase
EXW60_24170	COG0577	efflux transmembrane transporter activity
EXW60_24175	COG1136	(ABC) transporter
EXW60_24190	COG0488	(ABC) transporter
EXW60_24195	COG0667	Aldo Keto reductase
EXW60_24200	COG0583	DNA-binding transcription factor activity
EXW60_24225	COG2205	protein histidine kinase activity
EXW60_24230	COG0745	RESPONSE REGULATOR receiver
EXW60_24240	COG3773	Cell wall hydrolase
EXW60_24245	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW60_24255	COG3386	PFAM SMP-30 Gluconolaconase
EXW60_24265	COG0604	alcohol dehydrogenase
EXW60_24325	COG2959	enzyme of heme biosynthesis
EXW60_24355	COG3483	tryptophan 2,3-dioxygenase activity
EXW60_24360	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW60_24365	COG3844	kynureninase activity
EXW60_24370	COG1309	transcriptional regulator
EXW60_24385	COG3284	Transcriptional regulator
EXW60_24400	COG1349	DNA-binding transcription factor activity
EXW60_24425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW60_24430	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW60_24435	COG0022	dehydrogenase e1 component
EXW60_24440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW60_24450	COG2223	nitrite transmembrane transporter activity
EXW60_24460	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_24465	COG0456	acetyltransferase
EXW60_24465	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW60_24500	COG4176	ABC-type proline glycine betaine transport system permease component
EXW60_24505	COG4175	Glycine betaine
EXW60_24505	COG0517	IMP dehydrogenase activity
EXW60_24530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW60_24535	COG2153	protein acetylation
EXW60_24540	COG3397	chitin binding
EXW60_24550	COG1819	glycosyl
EXW60_24565	COG2205	protein histidine kinase activity
EXW60_24570	COG2315	Protein conserved in bacteria
EXW60_24615	COG3973	AAA domain
EXW60_24625	COG2105	PFAM AIG2 family protein
EXW60_24630	COG0514	ATP-dependent DNA helicase (RecQ)
EXW60_24650	COG4637	Psort location Cytoplasmic, score
EXW60_24660	COG1227	inorganic diphosphatase activity
EXW60_24665	COG3397	chitin binding
EXW60_24675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW60_24680	COG1115	amino acid carrier protein
EXW60_24685	COG1012	belongs to the aldehyde dehydrogenase family
EXW60_24690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW60_24700	COG3938	Belongs to the proline racemase family
EXW60_24705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW60_24745	COG0586	Pfam SNARE associated Golgi protein
EXW60_24760	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW60_24765	COG4166	transmembrane transport
EXW60_24775	COG4948	Mandelate Racemase Muconate Lactonizing
EXW60_24795	COG0667	Aldo Keto reductase
EXW60_24840	COG2936	dipeptidyl-peptidase activity
EXW60_24850	COG0745	RESPONSE REGULATOR receiver
EXW60_24870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW60_24905	COG1307	EDD domain protein, DegV family
EXW60_24965	COG2814	Major facilitator Superfamily
EXW60_24975	COG1664	Polymer-forming cytoskeletal
EXW60_24980	COG0789	Transcriptional regulator
EXW60_24985	COG4533	DNA binding
EXW60_24990	COG0477	Major facilitator Superfamily
EXW60_24990	COG2814	Major facilitator Superfamily
EXW60_25010	COG2261	transglycosylase associated protein
EXW60_25025	COG2226	methyltransferase
EXW60_25060	COG0436	Aminotransferase
EXW60_25065	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW60_25090	COG1131	(ABC) transporter
EXW60_25095	COG2188	Transcriptional regulator
EXW60_25135	COG0628	permease
EXW60_25145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW60_25175	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW60_25185	COG0697	spore germination
EXW60_25190	COG2318	DinB family
EXW60_25240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW60_25250	COG2814	Major facilitator Superfamily
EXW60_25270	COG0488	(ABC) transporter
EXW60_25275	COG1033	growth of symbiont in host cell
EXW60_25275	COG2409	Drug exporters of the RND superfamily
EXW60_25285	COG1309	transcriptional regulator
EXW60_25305	COG0287	Prephenate dehydrogenase
EXW60_25320	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW60_25320	COG1605	Chorismate mutase
EXW60_25350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EXW60_25375	COG0346	lactoylglutathione lyase activity
EXW60_25385	COG0431	NADPH-dependent FMN reductase
EXW60_25415	COG0579	oxidoreductase
EXW60_25420	COG1879	ABC-type sugar transport system periplasmic component
EXW60_25430	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW60_25435	COG1129	ABC transporter
EXW60_25440	COG2390	Transcriptional regulator
EXW60_25460	COG2226	methyltransferase
EXW60_25475	COG0346	lactoylglutathione lyase activity
EXW60_25480	COG2329	Antibiotic biosynthesis monooxygenase
EXW60_25500	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW60_25515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW60_25520	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW60_25525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW60_25530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW60_25535	COG3239	Fatty acid desaturase
EXW60_25555	COG3655	Transcriptional regulator
EXW60_25600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW60_25605	COG0346	lactoylglutathione lyase activity
EXW60_25630	COG0714	Associated with various cellular activities
EXW60_25650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW60_25655	COG0753	catalase activity
EXW60_25675	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW60_25695	COG0778	Nitroreductase
EXW60_25700	COG1846	Transcriptional regulator
EXW60_25720	COG1051	belongs to the nudix hydrolase family
EXW60_25725	COG3831	ATPase activity
EXW60_25725	COG4884	unkown
EXW60_25745	COG2207	Transcriptional regulator
EXW60_25750	COG0456	acetyltransferase
EXW60_25765	COG0697	spore germination
EXW60_25770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW60_25780	COG1671	Belongs to the UPF0178 family
EXW60_25800	COG0596	Alpha beta hydrolase
EXW60_25810	COG0456	acetyltransferase
EXW60_25810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW60_25835	COG0730	response to heat
EXW60_25845	COG0833	amino acid
EXW60_25855	COG4335	DNA alkylation repair
EXW60_25885	COG0681	Belongs to the peptidase S26 family
EXW60_25890	COG0768	penicillin binding
EXW60_25900	COG3104	oligopeptide transport
EXW60_25905	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW60_25920	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW60_25925	COG1984	allophanate hydrolase subunit 2
EXW60_25930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW60_25935	COG1414	Transcriptional regulator
EXW60_25965	COG1960	acyl-CoA dehydrogenase activity
EXW60_25980	COG0346	lactoylglutathione lyase activity
EXW60_25990	COG0640	Transcriptional regulator
EXW60_26000	COG3314	Sporulation integral membrane protein YlbJ
EXW60_26020	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW60_26035	COG3848	Pyruvate phosphate dikinase
EXW60_26035	COG0574	Belongs to the PEP-utilizing enzyme family
EXW60_26045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW60_26050	COG1876	peptidase activity
EXW60_26060	COG5002	protein histidine kinase activity
EXW60_26065	COG0745	RESPONSE REGULATOR receiver
EXW60_26070	COG4990	cell redox homeostasis
EXW60_26095	COG5002	protein histidine kinase activity
EXW60_26100	COG0745	RESPONSE REGULATOR receiver
EXW60_26110	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW60_26125	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW60_26130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW60_26135	COG1121	(ABC) transporter
EXW60_26160	COG3320	Male sterility
EXW60_26160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW60_26165	COG1309	transcriptional regulator
EXW60_26170	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_26175	COG1522	sequence-specific DNA binding
EXW60_26190	COG0346	lactoylglutathione lyase activity
EXW60_26220	COG2226	methyltransferase
EXW60_26230	COG2814	Major facilitator Superfamily
EXW60_26260	COG0745	RESPONSE REGULATOR receiver
EXW60_26265	COG5002	protein histidine kinase activity
EXW60_26265	COG3850	Histidine kinase
EXW60_26295	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW60_26310	COG2309	aminopeptidase activity
EXW60_26320	COG1690	Belongs to the RtcB family
EXW60_26330	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW60_26350	COG1136	(ABC) transporter
EXW60_26355	COG0577	efflux transmembrane transporter activity
EXW60_26375	COG5002	protein histidine kinase activity
EXW60_26375	COG3850	Histidine kinase
EXW60_26390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW60_26410	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW60_26430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW60_26460	COG5444	nuclease activity
EXW60_26510	COG2814	Major facilitator Superfamily
EXW60_26545	COG0477	Major facilitator Superfamily
EXW60_26560	COG1846	Transcriptional regulator
EXW60_26565	COG2814	Major facilitator Superfamily
EXW60_26610	COG0789	Transcriptional regulator
EXW60_26645	COG1476	TRANSCRIPTIONal
EXW60_26660	COG1288	antiporter activity
EXW60_26665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW60_26715	COG3718	enzyme involved in inositol metabolism
EXW60_26720	COG0191	fructose-bisphosphate aldolase activity
EXW60_26745	COG0673	inositol 2-dehydrogenase activity
EXW60_26750	COG2814	Major facilitator Superfamily
EXW60_26755	COG1609	Transcriptional regulator
EXW60_26790	COG2002	toxin-antitoxin pair type II binding
EXW60_26810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW60_26820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW60_26875	COG4187	Peptidase family M20/M25/M40
EXW60_26890	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW60_26905	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW60_26945	COG1122	ATPase activity
EXW60_26970	COG1288	antiporter activity
EXW60_26975	COG2356	endonuclease I
EXW60_26980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW60_26985	COG3620	sequence-specific DNA binding
EXW60_27000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW60_27020	COG1785	Belongs to the alkaline phosphatase family
EXW60_27025	COG0778	Nitroreductase
EXW60_27030	COG1733	regulation of RNA biosynthetic process
EXW60_27050	COG1028	Short-chain dehydrogenase reductase Sdr
EXW60_27060	COG1131	(ABC) transporter
EXW60_27090	COG1595	DNA-templated transcription, initiation
EXW60_27105	COG1011	Hydrolase
EXW60_27110	COG2365	Tyrosine phosphatase family
EXW60_27135	COG1136	(ABC) transporter
EXW60_27135	COG0577	efflux transmembrane transporter activity
EXW60_27150	COG0628	permease
EXW60_27155	COG2261	transglycosylase associated protein
EXW60_27190	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW60_27200	COG1253	flavin adenine dinucleotide binding
EXW60_27205	COG0789	Transcriptional regulator
EXW60_27210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW60_27235	COG0697	spore germination
EXW60_27245	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW60_27250	COG3813	Protein conserved in bacteria
EXW60_27255	COG2706	6-phosphogluconolactonase activity
EXW60_27260	COG1070	Carbohydrate kinase
EXW60_27270	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW60_27275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW60_27280	COG4702	Belongs to the UPF0303 family
EXW60_27290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW60_27310	COG0384	phenazine biosynthesis protein PhzF
EXW60_27330	COG0318	PFAM AMP-dependent synthetase and ligase
EXW60_27335	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW60_27340	COG1733	regulation of RNA biosynthetic process
EXW60_27355	COG1191	sigma factor activity
EXW60_27415	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW60_27505	COG2140	Oxalate decarboxylase
EXW60_27525	COG0024	Methionine aminopeptidase
EXW60_27530	COG1923	regulation of RNA biosynthetic process
EXW60_27540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW60_27555	COG0776	regulation of translation
EXW60_27560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW60_27565	COG0367	asparagine synthase
EXW60_27590	COG0542	response to heat
EXW60_27600	COG3397	chitin binding
EXW60_27690	COG1404	Belongs to the peptidase S8 family
EXW60_27710	COG2814	Major facilitator Superfamily
EXW60_27715	COG2234	aminopeptidase activity
EXW60_27725	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW60_27740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW60_27745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW60_27750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW60_27760	COG0456	acetyltransferase
EXW60_27790	COG0741	lytic transglycosylase activity
EXW60_27805	COG1674	ftsk spoiiie
EXW60_27820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW60_27845	COG5002	protein histidine kinase activity
EXW60_27870	COG0024	Methionine aminopeptidase
EXW60_27900	COG1396	sequence-specific DNA binding
EXW60_27990	COG0741	lytic transglycosylase activity
EXW60_27990	COG0791	NLP P60 protein
EXW60_28000	COG0791	NLP P60 protein
EXW60_28000	COG3883	PFAM NLP P60 protein
EXW60_28070	COG2002	toxin-antitoxin pair type II binding
EXW60_28080	COG1923	regulation of RNA biosynthetic process
EXW60_28100	COG0582	viral genome integration into host DNA
EXW60_28115	COG2732	(Barnase) inhibitor
EXW60_28190	COG0662	Cupin 2, conserved barrel domain protein
EXW60_28200	COG1923	regulation of RNA biosynthetic process
EXW60_28225	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW60_28255	COG4974	Belongs to the 'phage' integrase family
EXW60_28275	COG1136	(ABC) transporter
EXW60_28315	COG0450	alkyl hydroperoxide reductase
EXW60_28320	COG0833	amino acid
EXW60_28330	COG1982	Orn Lys Arg decarboxylase major
EXW60_28350	COG4175	Glycine betaine
EXW60_28350	COG0517	IMP dehydrogenase activity
EXW60_28355	COG4176	ABC-type proline glycine betaine transport system permease component
EXW60_28400	COG3344	reverse transcriptase
EXW60_28420	COG1329	Transcriptional regulator
EXW60_28460	COG1131	(ABC) transporter
EXW60_28465	COG1725	Transcriptional regulator
EXW60_28480	COG0745	RESPONSE REGULATOR receiver
EXW60_28485	COG2205	protein histidine kinase activity
EXW60_28500	COG1136	(ABC) transporter
EXW60_28505	COG0577	efflux transmembrane transporter activity
EXW60_28520	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW60_28520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW60_28545	COG1136	(ABC) transporter
EXW60_28570	COG1309	transcriptional regulator
EXW60_28580	COG3858	chitin binding
EXW60_28585	COG0697	spore germination
EXW60_28605	COG0697	spore germination
EXW60_28615	COG0697	spore germination
EXW60_28620	COG2508	Transcriptional regulator
EXW60_28620	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW60_28650	COG4974	Belongs to the 'phage' integrase family
EXW60_28665	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW60_28675	COG2239	Acts as a magnesium transporter
EXW60_28680	COG0772	Belongs to the SEDS family
EXW60_28685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW60_28690	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW60_28695	COG1073	alpha beta
EXW60_28700	COG2267	carboxylic ester hydrolase activity
EXW60_28705	COG1285	pathogenesis
EXW60_28710	COG0833	amino acid
EXW60_28745	COG0745	RESPONSE REGULATOR receiver
EXW60_28765	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW60_28790	COG1396	sequence-specific DNA binding
EXW60_28840	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW60_28855	COG2002	toxin-antitoxin pair type II binding
EXW60_28940	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW60_28965	COG2814	Major facilitator Superfamily
EXW60_29020	COG1923	regulation of RNA biosynthetic process
EXW60_29030	COG2002	toxin-antitoxin pair type II binding
EXW60_29035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW60_29035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW60_29040	COG1252	NADH dehydrogenase
EXW60_29055	COG0697	spore germination
EXW60_29085	COG2239	Acts as a magnesium transporter
EXW60_29095	COG0657	acetylesterase activity
EXW60_29095	COG2755	lipolytic protein G-D-S-L family
EXW60_29115	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW60_29125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW60_29195	COG1846	Transcriptional regulator
EXW60_29235	COG4641	Protein conserved in bacteria
EXW60_29240	COG2089	acid synthase
EXW60_29255	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW60_29260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW60_29265	COG1088	dTDP-glucose 4,6-dehydratase activity
EXW60_29270	COG1086	Polysaccharide biosynthesis protein
EXW60_29360	COG1396	sequence-specific DNA binding
EXW60_29465	COG3883	PFAM NLP P60 protein
EXW60_29465	COG0791	NLP P60 protein
EXW60_29575	COG0582	viral genome integration into host DNA
EXW60_29620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW60_29675	COG3409	Peptidoglycan-binding domain 1 protein
EXW60_29685	COG0582	viral genome integration into host DNA
EXW60_29715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW60_29740	COG1247	-acetyltransferase
EXW60_29745	COG1285	pathogenesis