locus-tag	class	description
EXW63_00010	COG0438	transferase activity, transferring glycosyl groups
EXW63_00015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW63_00020	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW63_00025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW63_00040	COG0477	Major facilitator Superfamily
EXW63_00040	COG2814	Major facilitator Superfamily
EXW63_00045	COG4533	DNA binding
EXW63_00050	COG0789	Transcriptional regulator
EXW63_00055	COG1664	Polymer-forming cytoskeletal
EXW63_00065	COG2814	Major facilitator Superfamily
EXW63_00080	COG1335	isochorismatase
EXW63_00110	COG1307	EDD domain protein, DegV family
EXW63_00130	COG1164	Oligoendopeptidase f
EXW63_00160	COG0745	RESPONSE REGULATOR receiver
EXW63_00165	COG5002	protein histidine kinase activity
EXW63_00170	COG2936	dipeptidyl-peptidase activity
EXW63_00215	COG0667	Aldo Keto reductase
EXW63_00235	COG4948	Mandelate Racemase Muconate Lactonizing
EXW63_00245	COG4166	transmembrane transport
EXW63_00250	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW63_00265	COG0586	Pfam SNARE associated Golgi protein
EXW63_00315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW63_00320	COG3938	Belongs to the proline racemase family
EXW63_00330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW63_00335	COG1012	belongs to the aldehyde dehydrogenase family
EXW63_00340	COG1115	amino acid carrier protein
EXW63_00345	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW63_00365	COG2318	DinB family
EXW63_00370	COG3397	chitin binding
EXW63_00375	COG1227	inorganic diphosphatase activity
EXW63_00395	COG4637	Psort location Cytoplasmic, score
EXW63_00415	COG0514	ATP-dependent DNA helicase (RecQ)
EXW63_00420	COG2105	PFAM AIG2 family protein
EXW63_00435	COG3973	AAA domain
EXW63_00480	COG2315	Protein conserved in bacteria
EXW63_00485	COG2205	protein histidine kinase activity
EXW63_00500	COG1819	glycosyl
EXW63_00510	COG3397	chitin binding
EXW63_00515	COG2153	protein acetylation
EXW63_00520	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW63_00545	COG0517	IMP dehydrogenase activity
EXW63_00545	COG4175	Glycine betaine
EXW63_00550	COG4176	ABC-type proline glycine betaine transport system permease component
EXW63_00585	COG0456	acetyltransferase
EXW63_00585	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW63_00590	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_00600	COG2223	nitrite transmembrane transporter activity
EXW63_00630	COG1349	DNA-binding transcription factor activity
EXW63_00660	COG1309	transcriptional regulator
EXW63_00665	COG3844	kynureninase activity
EXW63_00670	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW63_00675	COG3483	tryptophan 2,3-dioxygenase activity
EXW63_00705	COG2959	enzyme of heme biosynthesis
EXW63_00720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW63_00750	COG0604	alcohol dehydrogenase
EXW63_00755	COG3773	Cell wall hydrolase
EXW63_00765	COG0745	RESPONSE REGULATOR receiver
EXW63_00770	COG2205	protein histidine kinase activity
EXW63_00775	COG0583	DNA-binding transcription factor activity
EXW63_00780	COG0667	Aldo Keto reductase
EXW63_00785	COG0488	(ABC) transporter
EXW63_00795	COG1136	(ABC) transporter
EXW63_00800	COG0577	efflux transmembrane transporter activity
EXW63_00820	COG0460	homoserine dehydrogenase
EXW63_00825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW63_00835	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW63_00885	COG2124	cytochrome p450
EXW63_00935	COG0561	phosphatase activity
EXW63_00970	COG5002	protein histidine kinase activity
EXW63_00975	COG0768	penicillin binding
EXW63_00985	COG1819	glycosyl
EXW63_00990	COG1794	racemase activity, acting on amino acids and derivatives
EXW63_00995	COG4720	Psort location CytoplasmicMembrane, score
EXW63_01000	COG1122	ATPase activity
EXW63_01015	COG2205	protein histidine kinase activity
EXW63_01025	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW63_01035	COG0745	RESPONSE REGULATOR receiver
EXW63_01040	COG5002	protein histidine kinase activity
EXW63_01045	COG0604	alcohol dehydrogenase
EXW63_01050	COG0671	phosphoesterase, PA-phosphatase related
EXW63_01055	COG0768	penicillin binding
EXW63_01090	COG1132	(ABC) transporter
EXW63_01095	COG1132	(ABC) transporter
EXW63_01095	COG2375	cellular response to nickel ion
EXW63_01110	COG2814	Major facilitator Superfamily
EXW63_01120	COG1733	regulation of RNA biosynthetic process
EXW63_01135	COG0584	glycerophosphoryl diester phosphodiesterase
EXW63_01150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW63_01155	COG0697	spore germination
EXW63_01175	COG0494	nUDIX hydrolase
EXW63_01185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW63_01190	COG2223	nitrite transmembrane transporter activity
EXW63_01200	COG2816	NAD+ diphosphatase activity
EXW63_01205	COG0592	DNA-directed DNA polymerase activity
EXW63_01210	COG1051	belongs to the nudix hydrolase family
EXW63_01235	COG3878	Protein conserved in bacteria
EXW63_01260	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW63_01275	COG2318	DinB family
EXW63_01300	COG0322	excinuclease ABC activity
EXW63_01320	COG3961	Belongs to the TPP enzyme family
EXW63_01330	COG1132	(ABC) transporter
EXW63_01345	COG1183	phosphatidylcholine synthase activity
EXW63_01350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW63_01375	COG1011	Hydrolase
EXW63_01380	COG0745	RESPONSE REGULATOR receiver
EXW63_01385	COG5002	protein histidine kinase activity
EXW63_01415	COG1136	(ABC) transporter
EXW63_01420	COG0577	efflux transmembrane transporter activity
EXW63_01430	COG1073	alpha beta
EXW63_01435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW63_01440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW63_01455	COG1523	belongs to the glycosyl hydrolase 13 family
EXW63_01460	COG3227	Zinc metalloprotease (Elastase)
EXW63_01470	COG0737	Belongs to the 5'-nucleotidase family
EXW63_01480	COG0201	protein transport
EXW63_01500	COG0697	spore germination
EXW63_01505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW63_01520	COG2323	membrane
EXW63_01550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW63_01555	COG0697	spore germination
EXW63_01585	COG1309	transcriptional regulator
EXW63_01610	COG1733	regulation of RNA biosynthetic process
EXW63_01615	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_01640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW63_01670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW63_01700	COG2318	DinB family
EXW63_01705	COG0572	uridine kinase
EXW63_01745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW63_01750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW63_01755	COG1024	Enoyl-CoA hydratase
EXW63_01760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW63_01765	COG0511	ligase activity, forming carbon-carbon bonds
EXW63_01770	COG0439	Biotin carboxylase
EXW63_01775	COG1960	acyl-CoA dehydrogenase activity
EXW63_01785	COG1309	transcriptional regulator
EXW63_01795	COG1131	(ABC) transporter
EXW63_01805	COG1408	metallophosphoesterase
EXW63_01815	COG0823	Involved in the tonB-independent uptake of proteins
EXW63_01820	COG3397	chitin binding
EXW63_01850	COG0697	spore germination
EXW63_01865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW63_01865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW63_01870	COG1252	NADH dehydrogenase
EXW63_01905	COG0768	penicillin binding
EXW63_01910	COG0768	penicillin binding
EXW63_01920	COG1595	DNA-templated transcription, initiation
EXW63_01930	COG0577	efflux transmembrane transporter activity
EXW63_01935	COG1136	(ABC) transporter
EXW63_01940	COG2205	protein histidine kinase activity
EXW63_01945	COG0745	RESPONSE REGULATOR receiver
EXW63_01950	COG0768	penicillin binding
EXW63_01975	COG1686	Belongs to the peptidase S11 family
EXW63_01985	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_01990	COG5002	protein histidine kinase activity
EXW63_02005	COG1136	(ABC) transporter
EXW63_02020	COG0110	maltose O-acetyltransferase activity
EXW63_02025	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW63_02045	COG0588	phosphoglycerate mutase activity
EXW63_02055	COG0693	protein deglycase activity
EXW63_02065	COG0500	methyltransferase
EXW63_02065	COG3615	Tellurite resistance protein tehB
EXW63_02135	COG2971	BadF BadG BcrA BcrD
EXW63_02140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW63_02160	COG1649	PFAM Uncharacterised BCR, COG1649
EXW63_02180	COG1595	DNA-templated transcription, initiation
EXW63_02185	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW63_02220	COG1396	sequence-specific DNA binding
EXW63_02240	COG1132	(ABC) transporter
EXW63_02245	COG1132	(ABC) transporter
EXW63_02255	COG2258	MOSC domain
EXW63_02260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW63_02265	COG0583	DNA-binding transcription factor activity
EXW63_02280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW63_02285	COG0583	DNA-binding transcription factor activity
EXW63_02315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW63_02325	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW63_02330	COG0596	Alpha beta hydrolase
EXW63_02370	COG1247	-acetyltransferase
EXW63_02385	COG0531	amino acid
EXW63_02390	COG0697	spore germination
EXW63_02400	COG1309	transcriptional regulator
EXW63_02405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW63_02415	COG1846	Transcriptional regulator
EXW63_02465	COG1253	flavin adenine dinucleotide binding
EXW63_02490	COG0028	Belongs to the TPP enzyme family
EXW63_02505	COG0596	Alpha beta hydrolase
EXW63_02515	COG1136	(ABC) transporter
EXW63_02525	COG3655	Transcriptional regulator
EXW63_02530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW63_02535	COG1187	pseudouridine synthase activity
EXW63_02550	COG2329	Antibiotic biosynthesis monooxygenase
EXW63_02565	COG1115	amino acid carrier protein
EXW63_02570	COG2318	DinB family
EXW63_02580	COG0776	regulation of translation
EXW63_02595	COG2814	Major facilitator Superfamily
EXW63_02600	COG3251	PFAM MbtH domain protein
EXW63_02605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW63_02610	COG3433	isochorismatase activity
EXW63_02610	COG1535	isochorismatase
EXW63_02615	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW63_02620	COG1169	isochorismate synthase
EXW63_02625	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_02630	COG2223	nitrite transmembrane transporter activity
EXW63_02650	COG0420	3'-5' exonuclease activity
EXW63_02665	COG1024	Enoyl-CoA hydratase
EXW63_02670	COG1280	lysine exporter protein (LysE YggA)
EXW63_02675	COG1012	belongs to the aldehyde dehydrogenase family
EXW63_02680	COG2084	Dehydrogenase
EXW63_02685	COG1960	acyl-CoA dehydrogenase activity
EXW63_02690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW63_02695	COG2079	MmgE PrpD family protein
EXW63_02700	COG0372	Belongs to the citrate synthase family
EXW63_02710	COG2814	Major facilitator Superfamily
EXW63_02720	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW63_02720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW63_02740	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_02765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW63_02825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW63_02830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW63_02835	COG0671	phosphoesterase, PA-phosphatase related
EXW63_02845	COG3064	Membrane
EXW63_02845	COG4991	sh3 domain protein
EXW63_02845	COG0515	serine threonine protein kinase
EXW63_02875	COG5293	efflux transmembrane transporter activity
EXW63_02930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW63_02935	COG4479	Belongs to the UPF0346 family
EXW63_02945	COG1509	lysine 2,3-aminomutase activity
EXW63_02950	COG3829	transcription factor binding
EXW63_02955	COG0456	acetyltransferase
EXW63_02960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW63_02965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW63_02970	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW63_02975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW63_02990	COG5506	Protein of unknown function (DUF1694)
EXW63_02995	COG1012	belongs to the aldehyde dehydrogenase family
EXW63_03000	COG1253	flavin adenine dinucleotide binding
EXW63_03035	COG1174	glycine betaine transport
EXW63_03040	COG1125	glycine betaine transport
EXW63_03040	COG0517	IMP dehydrogenase activity
EXW63_03055	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW63_03065	COG1070	Carbohydrate kinase
EXW63_03080	COG1064	alcohol dehydrogenase
EXW63_03085	COG1737	Transcriptional regulator
EXW63_03090	COG2197	response regulator
EXW63_03095	COG2203	Gaf domain
EXW63_03095	COG4585	Histidine kinase
EXW63_03100	COG0668	transmembrane transport
EXW63_03110	COG1335	isochorismatase
EXW63_03130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW63_03135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW63_03140	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW63_03155	COG0367	asparagine synthase
EXW63_03160	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW63_03165	COG1999	signal sequence binding
EXW63_03170	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW63_03185	COG0805	protein transport
EXW63_03190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW63_03195	COG1272	protein, Hemolysin III
EXW63_03200	COG0204	Acyl-transferase
EXW63_03210	COG0768	penicillin binding
EXW63_03265	COG0546	phosphoglycolate phosphatase activity
EXW63_03275	COG4473	ABC transporter
EXW63_03280	COG1131	(ABC) transporter
EXW63_03285	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW63_03290	COG0456	acetyltransferase
EXW63_03300	COG1794	racemase activity, acting on amino acids and derivatives
EXW63_03310	COG2610	gluconate transmembrane transporter activity
EXW63_03340	COG0733	neurotransmitter:sodium symporter activity
EXW63_03345	COG0017	Asparaginyl-tRNA synthetase
EXW63_03355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW63_03410	COG0018	arginyl-trna synthetase
EXW63_03415	COG2521	methyltransferase
EXW63_03415	COG2136	Putative SAM-dependent methyltransferase
EXW63_03430	COG1413	lyase activity
EXW63_03450	COG0488	(ABC) transporter
EXW63_03455	COG1418	mRNA catabolic process
EXW63_03585	COG4653	Phage capsid family
EXW63_03590	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EXW63_03605	COG1783	phage Terminase large subunit
EXW63_03610	COG5484	DNA packaging
EXW63_03630	COG0582	viral genome integration into host DNA
EXW63_03655	COG0582	viral genome integration into host DNA
EXW63_03740	COG2856	Zn peptidase
EXW63_03750	COG2359	stage V sporulation protein S
EXW63_03775	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW63_03780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW63_03785	COG2146	nitrite reductase [NAD(P)H] activity
EXW63_03790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW63_03790	COG1587	Uroporphyrinogen-III synthase
EXW63_03800	COG1648	precorrin-2 dehydrogenase activity
EXW63_03820	COG2223	nitrite transmembrane transporter activity
EXW63_03830	COG0314	molybdopterin synthase activity
EXW63_03835	COG0303	'Molybdopterin
EXW63_03840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW63_03845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW63_03850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW63_03855	COG2181	nitrate reductase activity
EXW63_03860	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW63_03865	COG1140	nitrate reductase beta subunit
EXW63_03870	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW63_03875	COG0714	Associated with various cellular activities
EXW63_03880	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW63_03885	COG1305	Transglutaminase-like
EXW63_03890	COG0386	Belongs to the glutathione peroxidase family
EXW63_03900	COG0426	domain, Protein
EXW63_03900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW63_03925	COG1595	DNA-templated transcription, initiation
EXW63_03930	COG0604	alcohol dehydrogenase
EXW63_03940	COG0346	lactoylglutathione lyase activity
EXW63_03945	COG1082	Xylose isomerase domain protein TIM barrel
EXW63_03965	COG2226	methyltransferase
EXW63_03990	COG3874	Sporulation protein YtfJ
EXW63_04010	COG0456	acetyltransferase
EXW63_04035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW63_04040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW63_04045	COG1819	glycosyl
EXW63_04060	COG4106	trans-aconitate 2-methyltransferase activity
EXW63_04065	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW63_04075	COG2814	Major facilitator Superfamily
EXW63_04080	COG1846	Transcriptional regulator
EXW63_04085	COG0561	phosphatase activity
EXW63_04095	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW63_04110	COG2211	Major facilitator Superfamily
EXW63_04120	COG0494	nUDIX hydrolase
EXW63_04125	COG1876	peptidase activity
EXW63_04140	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW63_04160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW63_04165	COG1114	Component of the transport system for branched-chain amino acids
EXW63_04190	COG1253	flavin adenine dinucleotide binding
EXW63_04195	COG2839	Protein conserved in bacteria
EXW63_04200	COG0702	epimerase
EXW63_04215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW63_04225	COG1607	acyl-coa hydrolase
EXW63_04230	COG3689	TIGRFAM TIGR03943 family protein
EXW63_04235	COG0701	Predicted permease
EXW63_04245	COG2244	polysaccharide biosynthetic process
EXW63_04250	COG0586	Pfam SNARE associated Golgi protein
EXW63_04255	COG1051	belongs to the nudix hydrolase family
EXW63_04260	COG5337	Spore coat protein CotH
EXW63_04270	COG0406	alpha-ribazole phosphatase activity
EXW63_04280	COG0346	lactoylglutathione lyase activity
EXW63_04285	COG4166	transmembrane transport
EXW63_04295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW63_04300	COG1902	pentaerythritol trinitrate reductase activity
EXW63_04305	COG2205	protein histidine kinase activity
EXW63_04310	COG0745	RESPONSE REGULATOR receiver
EXW63_04315	COG0577	efflux transmembrane transporter activity
EXW63_04320	COG1136	(ABC) transporter
EXW63_04345	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW63_04350	COG0456	acetyltransferase
EXW63_04355	COG0523	cobalamin synthesis protein
EXW63_04360	COG4989	oxidoreductase activity
EXW63_04365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW63_04370	COG1231	oxidoreductase activity
EXW63_04380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW63_04395	COG0783	Belongs to the Dps family
EXW63_04400	COG3949	Membrane
EXW63_04445	COG0667	Aldo Keto reductase
EXW63_04450	COG0640	Transcriptional regulator
EXW63_04455	COG1404	Belongs to the peptidase S8 family
EXW63_04460	COG2002	toxin-antitoxin pair type II binding
EXW63_04465	COG0577	efflux transmembrane transporter activity
EXW63_04470	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW63_04500	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW63_04510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW63_04515	COG1279	arginine transmembrane transporter activity
EXW63_04520	COG2814	Major facilitator Superfamily
EXW63_04530	COG1082	Xylose isomerase domain protein TIM barrel
EXW63_04540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW63_04560	COG1247	-acetyltransferase
EXW63_04565	COG1285	pathogenesis
EXW63_04580	COG1316	TRANSCRIPTIONal
EXW63_04595	COG0083	homoserine kinase activity
EXW63_04605	COG0460	homoserine dehydrogenase
EXW63_04615	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EXW63_04635	COG4122	O-methyltransferase activity
EXW63_04640	COG0300	oxidoreductase activity
EXW63_04645	COG5002	protein histidine kinase activity
EXW63_04650	COG0745	RESPONSE REGULATOR receiver
EXW63_04655	COG1132	(ABC) transporter
EXW63_04665	COG0791	NLP P60 protein
EXW63_04665	COG1388	LysM domain
EXW63_04680	COG1686	Belongs to the peptidase S11 family
EXW63_04705	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW63_04710	COG4988	ABC transporter
EXW63_04715	COG1294	oxidase, subunit
EXW63_04720	COG1271	oxidase subunit
EXW63_04730	COG0346	lactoylglutathione lyase activity
EXW63_04745	COG1942	4-Oxalocrotonate Tautomerase
EXW63_04755	COG0583	DNA-binding transcription factor activity
EXW63_04775	COG0411	ABC transporter
EXW63_04785	COG0523	cobalamin synthesis protein
EXW63_04790	COG1231	oxidoreductase activity
EXW63_04805	COG0628	permease
EXW63_04815	COG0778	Nitroreductase
EXW63_04820	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW63_04825	COG1959	2 iron, 2 sulfur cluster binding
EXW63_04830	COG0583	DNA-binding transcription factor activity
EXW63_04835	COG0697	spore germination
EXW63_04845	COG4549	nuclear export factor GLE1
EXW63_04850	COG2372	response to copper ion
EXW63_04850	COG1276	copper resistance
EXW63_04860	COG1114	Component of the transport system for branched-chain amino acids
EXW63_04880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW63_04895	COG2132	Multicopper oxidase
EXW63_04900	COG0006	proline dipeptidase activity
EXW63_04915	COG0583	DNA-binding transcription factor activity
EXW63_04930	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW63_04945	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW63_04950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW63_04955	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW63_04965	COG2390	Transcriptional regulator
EXW63_04970	COG4257	antibiotic catabolic process
EXW63_04985	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW63_05020	COG0531	amino acid
EXW63_05025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW63_05035	COG1054	Belongs to the UPF0176 family
EXW63_05040	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW63_05055	COG0745	RESPONSE REGULATOR receiver
EXW63_05060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW63_05065	COG4166	transmembrane transport
EXW63_05070	COG1073	alpha beta
EXW63_05105	COG3384	dioxygenase
EXW63_05110	COG2814	Major facilitator Superfamily
EXW63_05135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW63_05140	COG0129	dihydroxy-acid dehydratase activity
EXW63_05150	COG0745	RESPONSE REGULATOR receiver
EXW63_05155	COG5002	protein histidine kinase activity
EXW63_05165	COG2132	Multicopper oxidase
EXW63_05170	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW63_05190	COG2323	membrane
EXW63_05195	COG5566	PFAM Mor transcription activator
EXW63_05205	COG0733	neurotransmitter:sodium symporter activity
EXW63_05210	COG2244	polysaccharide biosynthetic process
EXW63_05225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW63_05230	COG2223	nitrite transmembrane transporter activity
EXW63_05235	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW63_05245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW63_05255	COG0477	Major facilitator Superfamily
EXW63_05270	COG1695	Transcriptional regulator
EXW63_05335	COG3620	sequence-specific DNA binding
EXW63_05340	COG2502	aspartate--ammonia ligase
EXW63_05355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW63_05365	COG1846	Transcriptional regulator
EXW63_05370	COG0784	Response regulator, receiver
EXW63_05375	COG4191	Histidine kinase
EXW63_05380	COG0281	malic enzyme
EXW63_05385	COG1027	Aspartate ammonia-lyase
EXW63_05395	COG0528	UMP kinase activity
EXW63_05400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW63_05420	COG1131	(ABC) transporter
EXW63_05460	COG2733	membrane
EXW63_05465	COG3048	D-serine ammonia-lyase activity
EXW63_05480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW63_05485	COG0785	Cytochrome C biogenesis protein
EXW63_05505	COG3340	Belongs to the peptidase S51 family
EXW63_05510	COG0534	Mate efflux family protein
EXW63_05535	COG1757	Na H antiporter
EXW63_05540	COG1216	Glycosyl transferase, family 2
EXW63_05540	COG0438	transferase activity, transferring glycosyl groups
EXW63_05545	COG0697	spore germination
EXW63_05550	COG1802	Transcriptional regulator
EXW63_05580	COG0367	asparagine synthase
EXW63_05610	COG0406	alpha-ribazole phosphatase activity
EXW63_05660	COG3842	ATPase activity
EXW63_05665	COG0583	DNA-binding transcription factor activity
EXW63_05690	COG2329	Antibiotic biosynthesis monooxygenase
EXW63_05695	COG0412	Dienelactone hydrolase
EXW63_05735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW63_05750	COG4786	Flagellar basal body rod
EXW63_05755	COG1419	protein localization to endoplasmic reticulum
EXW63_05760	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW63_05765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW63_05775	COG1987	bacterial-type flagellum assembly
EXW63_05780	COG1338	Plays a role in the flagellum-specific transport system
EXW63_05790	COG1776	CheC inhibitor of MCP methylation
EXW63_05790	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW63_05795	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW63_05805	COG0741	lytic transglycosylase activity
EXW63_05810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW63_05840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW63_05845	COG0489	protein tyrosine kinase activity
EXW63_05860	COG0314	molybdopterin synthase activity
EXW63_05865	COG0303	'Molybdopterin
EXW63_05870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW63_05875	COG2116	formate transmembrane transporter activity
EXW63_05885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW63_05890	COG5609	conserved protein (DUF2294)
EXW63_05895	COG2427	Protein of unknown function (DUF1641)
EXW63_05900	COG3383	formate dehydrogenase (NAD+) activity
EXW63_05910	COG0861	Integral membrane protein TerC family
EXW63_05935	COG0784	Response regulator, receiver
EXW63_05935	COG0835	chemotaxis
EXW63_05950	COG1749	Flagellar hook protein flgE
EXW63_05970	COG1157	protein secretion by the type III secretion system
EXW63_05980	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW63_05985	COG1766	The M ring may be actively involved in energy transduction
EXW63_05995	COG1558	bacterial-type flagellum-dependent cell motility
EXW63_06000	COG1815	bacterial-type flagellum-dependent cell motility
EXW63_06020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW63_06025	COG1256	bacterial-type flagellum assembly
EXW63_06045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW63_06060	COG1776	CheC inhibitor of MCP methylation
EXW63_06060	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW63_06065	COG0643	Histidine kinase
EXW63_06065	COG2198	Histidine kinase
EXW63_06070	COG2201	protein-glutamate methylesterase activity
EXW63_06075	COG1360	Flagellar Motor Protein
EXW63_06080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW63_06090	COG1923	regulation of RNA biosynthetic process
EXW63_06110	COG2814	Major facilitator Superfamily
EXW63_06135	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW63_06140	COG2323	membrane
EXW63_06145	COG0534	Mate efflux family protein
EXW63_06150	COG4978	Transcriptional regulator
EXW63_06150	COG0789	Transcriptional regulator
EXW63_06155	COG0475	glutathione-regulated potassium exporter activity
EXW63_06165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW63_06170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW63_06175	COG3162	membrane
EXW63_06190	COG1280	lysine exporter protein (LysE YggA)
EXW63_06195	COG3403	YqcI/YcgG family
EXW63_06230	COG0328	RNA-DNA hybrid ribonuclease activity
EXW63_06250	COG0454	-acetyltransferase
EXW63_06265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW63_06315	COG0456	acetyltransferase
EXW63_06325	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW63_06335	COG2311	Membrane
EXW63_06340	COG2233	PERMEase
EXW63_06350	COG0024	Methionine aminopeptidase
EXW63_06360	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW63_06365	COG1199	ATP-dependent helicase activity
EXW63_06375	COG0116	Belongs to the methyltransferase superfamily
EXW63_06385	COG3599	regulation of cell shape
EXW63_06390	COG4474	Belongs to the UPF0398 family
EXW63_06425	COG3331	DNA recombination
EXW63_06430	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW63_06430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW63_06440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW63_06445	COG3935	DnaD domain protein
EXW63_06465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW63_06465	COG1199	ATP-dependent helicase activity
EXW63_06475	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW63_06480	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW63_06490	COG0617	tRNA 3'-terminal CCA addition
EXW63_06495	COG0438	transferase activity, transferring glycosyl groups
EXW63_06500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW63_06505	COG1803	Methylglyoxal synthase
EXW63_06510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW63_06515	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW63_06520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW63_06530	COG2738	Putative neutral zinc metallopeptidase
EXW63_06545	COG4347	Protein of unknown function (DUF1405)
EXW63_06560	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW63_06575	COG5582	Belongs to the UPF0302 family
EXW63_06580	COG0457	Tetratricopeptide repeat
EXW63_06585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW63_06595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW63_06610	COG0142	geranyltranstransferase activity
EXW63_06615	COG2226	methyltransferase
EXW63_06620	COG0142	geranyltranstransferase activity
EXW63_06625	COG0302	gtp cyclohydrolase
EXW63_06635	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW63_06655	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW63_06660	COG1160	GTP binding
EXW63_06690	COG1304	FMN binding
EXW63_06700	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW63_06705	COG0252	asparaginase activity
EXW63_06710	COG0492	ferredoxin-NADP+ reductase activity
EXW63_06730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW63_06745	COG1408	metallophosphoesterase
EXW63_06755	COG1266	CAAX protease self-immunity
EXW63_06760	COG0514	ATP-dependent DNA helicase (RecQ)
EXW63_06765	COG4955	Helix-turn-helix domain
EXW63_06775	COG1141	Ferredoxin
EXW63_06780	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW63_06790	COG4942	peptidase
EXW63_06795	COG2096	Adenosyltransferase
EXW63_06800	COG5002	protein histidine kinase activity
EXW63_06805	COG0745	RESPONSE REGULATOR receiver
EXW63_06810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW63_06815	COG1333	cytochrome c biogenesis protein
EXW63_06825	COG1187	pseudouridine synthase activity
EXW63_06830	COG0700	Nucleoside recognition
EXW63_06835	COG2715	membrane protein required for spore maturation
EXW63_06840	COG1686	Belongs to the peptidase S11 family
EXW63_06845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW63_06860	COG0392	lysyltransferase activity
EXW63_06860	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW63_06875	COG5002	protein histidine kinase activity
EXW63_06880	COG0582	viral genome integration into host DNA
EXW63_06890	COG1801	Protein of unknown function DUF72
EXW63_06895	COG3852	Histidine kinase
EXW63_06910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW63_06915	COG1392	Phosphate transport regulator
EXW63_06920	COG0306	phosphate transporter
EXW63_06925	COG0730	response to heat
EXW63_06970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW63_06980	COG1114	Component of the transport system for branched-chain amino acids
EXW63_06990	COG2197	response regulator
EXW63_06995	COG4585	Histidine kinase
EXW63_07000	COG4758	membrane
EXW63_07020	COG1757	Na H antiporter
EXW63_07040	COG0733	neurotransmitter:sodium symporter activity
EXW63_07045	COG1648	precorrin-2 dehydrogenase activity
EXW63_07065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW63_07070	COG0529	Catalyzes the synthesis of activated sulfate
EXW63_07075	COG2046	Belongs to the sulfate adenylyltransferase family
EXW63_07080	COG0175	sulfate reduction
EXW63_07090	COG0019	diaminopimelate decarboxylase activity
EXW63_07100	COG1368	sulfuric ester hydrolase activity
EXW63_07105	COG1183	phosphatidylcholine synthase activity
EXW63_07120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW63_07125	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW63_07135	COG0107	imidazoleglycerol-phosphate synthase activity
EXW63_07140	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW63_07145	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW63_07150	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW63_07160	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW63_07165	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW63_07175	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW63_07185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW63_07195	COG0440	acetolactate synthase activity
EXW63_07200	COG0028	Belongs to the TPP enzyme family
EXW63_07205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW63_07225	COG3874	Sporulation protein YtfJ
EXW63_07235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW63_07240	COG1301	dicarboxylic acid transport
EXW63_07250	COG1846	Transcriptional regulator
EXW63_07275	COG0534	Mate efflux family protein
EXW63_07300	COG0716	FMN binding
EXW63_07315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW63_07320	COG1696	Membrane protein involved in D-alanine export
EXW63_07325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW63_07330	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW63_07335	COG2070	2-Nitropropane dioxygenase
EXW63_07340	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW63_07350	COG1335	isochorismatase
EXW63_07360	COG1522	sequence-specific DNA binding
EXW63_07370	COG1266	CAAX protease self-immunity
EXW63_07375	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW63_07380	COG1131	(ABC) transporter
EXW63_07390	COG1131	(ABC) transporter
EXW63_07395	COG1725	Transcriptional regulator
EXW63_07405	COG1012	belongs to the aldehyde dehydrogenase family
EXW63_07410	COG2204	response regulator
EXW63_07425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW63_07430	COG0531	amino acid
EXW63_07435	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW63_07450	COG1780	Probably involved in ribonucleotide reductase function
EXW63_07470	COG0456	acetyltransferase
EXW63_07480	COG4873	Protein conserved in bacteria
EXW63_07485	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW63_07495	COG0720	synthase
EXW63_07500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW63_07505	COG5002	protein histidine kinase activity
EXW63_07510	COG2318	DinB family
EXW63_07520	COG1846	Transcriptional regulator
EXW63_07525	COG3852	Histidine kinase
EXW63_07535	COG2861	carbohydrate metabolic process
EXW63_07545	COG0235	Class ii aldolase
EXW63_07555	COG1349	DNA-binding transcription factor activity
EXW63_07565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW63_07580	COG3842	ATPase activity
EXW63_07585	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW63_07600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW63_07610	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW63_07615	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_07635	COG2030	dehydratase
EXW63_07645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW63_07650	COG0861	Integral membrane protein TerC family
EXW63_07655	COG2116	formate transmembrane transporter activity
EXW63_07665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW63_07670	COG1556	Lactate utilization protein
EXW63_07675	COG1139	Iron-sulfur cluster binding protein
EXW63_07680	COG0247	lactate metabolic process
EXW63_07685	COG2186	Transcriptional regulator
EXW63_07690	COG5002	protein histidine kinase activity
EXW63_07695	COG0745	RESPONSE REGULATOR receiver
EXW63_07705	COG3835	regulator
EXW63_07710	COG0277	FAD linked oxidase domain protein
EXW63_07715	COG0247	lactate metabolic process
EXW63_07720	COG2340	Cysteine-rich secretory protein family
EXW63_07730	COG0564	pseudouridine synthase activity
EXW63_07740	COG2409	Drug exporters of the RND superfamily
EXW63_07750	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW63_07755	COG1177	transmembrane transport
EXW63_07760	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW63_07770	COG1012	belongs to the aldehyde dehydrogenase family
EXW63_07805	COG0681	Belongs to the peptidase S26 family
EXW63_07810	COG1686	Belongs to the peptidase S11 family
EXW63_07850	COG0582	viral genome integration into host DNA
EXW63_07885	COG1668	transmembrane transport
EXW63_07890	COG4152	abc transporter atp-binding protein
EXW63_07915	COG1476	TRANSCRIPTIONal
EXW63_07920	COG0567	Dehydrogenase, E1 component
EXW63_07925	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW63_07945	COG2226	methyltransferase
EXW63_08005	COG5634	Uncharacterized conserved protein (DUF2278)
EXW63_08010	COG1620	l-lactate permease
EXW63_08020	COG0159	tryptophan synthase activity
EXW63_08025	COG0133	tryptophan synthase activity
EXW63_08030	COG0135	phosphoribosylanthranilate isomerase activity
EXW63_08035	COG0134	indole-3-glycerol-phosphate synthase activity
EXW63_08040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW63_08045	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW63_08045	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW63_08060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW63_08065	COG5492	domain, Protein
EXW63_08090	COG2382	esterase
EXW63_08095	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW63_08100	COG2153	protein acetylation
EXW63_08145	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW63_08160	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW63_08180	COG0457	Tetratricopeptide repeat
EXW63_08180	COG0463	Glycosyl transferase, family 2
EXW63_08200	COG1216	Glycosyl transferase, family 2
EXW63_08205	COG0772	Belongs to the SEDS family
EXW63_08210	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW63_08225	COG0564	pseudouridine synthase activity
EXW63_08235	COG2357	RelA SpoT domain protein
EXW63_08245	COG4116	CYTH
EXW63_08250	COG2346	COG2346, Truncated hemoglobins
EXW63_08260	COG1164	Oligoendopeptidase f
EXW63_08270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW63_08275	COG4862	establishment of competence for transformation
EXW63_08280	COG0861	Integral membrane protein TerC family
EXW63_08300	COG4166	transmembrane transport
EXW63_08305	COG0534	Mate efflux family protein
EXW63_08310	COG4608	Belongs to the ABC transporter superfamily
EXW63_08315	COG0444	Belongs to the ABC transporter superfamily
EXW63_08320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW63_08325	COG0601	transmembrane transport
EXW63_08330	COG4166	transmembrane transport
EXW63_08345	COG0180	Tryptophanyl-tRNA synthetase
EXW63_08365	COG5504	Zn-dependent protease
EXW63_08370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW63_08375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW63_08390	COG2267	carboxylic ester hydrolase activity
EXW63_08410	COG0561	phosphatase activity
EXW63_08425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW63_08435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW63_08470	COG1329	Transcriptional regulator
EXW63_08485	COG2996	Protein conserved in bacteria
EXW63_08490	COG1666	GTP binding
EXW63_08500	COG0004	ammonium transporteR
EXW63_08505	COG0753	catalase activity
EXW63_08525	COG0367	asparagine synthase
EXW63_08550	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW63_08600	COG1074	ATP-dependent DNA helicase activity
EXW63_08605	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW63_08615	COG0398	Pfam SNARE associated Golgi protein
EXW63_08620	COG4903	ComK protein
EXW63_08640	COG1278	Cold shock
EXW63_08650	COG2224	Isocitrate lyase
EXW63_08655	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW63_08660	COG3693	PFAM glycoside hydrolase, family 10
EXW63_08665	COG0697	spore germination
EXW63_08670	COG0840	transmembrane signaling receptor activity
EXW63_08675	COG0501	Belongs to the peptidase M48B family
EXW63_08695	COG0745	RESPONSE REGULATOR receiver
EXW63_08700	COG2205	protein histidine kinase activity
EXW63_08705	COG3708	Transcriptional regulator
EXW63_08705	COG2207	Transcriptional regulator
EXW63_08715	COG1595	DNA-templated transcription, initiation
EXW63_08730	COG1078	dGTPase activity
EXW63_08735	COG1408	metallophosphoesterase
EXW63_08750	COG4208	sulfate ABC transporter
EXW63_08760	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW63_08775	COG0318	PFAM AMP-dependent synthetase and ligase
EXW63_08785	COG0095	Lipoate-protein ligase
EXW63_08790	COG1234	tRNA 3'-trailer cleavage
EXW63_08800	COG1609	Transcriptional regulator
EXW63_08835	COG1511	domain protein
EXW63_08840	COG1309	transcriptional regulator
EXW63_08860	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW63_08865	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW63_08870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW63_08875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW63_08880	COG2329	Antibiotic biosynthesis monooxygenase
EXW63_08885	COG3428	Bacterial PH domain
EXW63_08890	COG3402	PFAM membrane-flanked domain
EXW63_08930	COG3428	Bacterial PH domain
EXW63_08935	COG3402	PFAM membrane-flanked domain
EXW63_08955	COG1556	Lactate utilization protein
EXW63_08960	COG1139	Iron-sulfur cluster binding protein
EXW63_08965	COG0247	lactate metabolic process
EXW63_08975	COG4473	ABC transporter
EXW63_08980	COG1131	(ABC) transporter
EXW63_08985	COG0537	adenosine 5'-monophosphoramidase activity
EXW63_09010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW63_09015	COG3973	AAA domain
EXW63_09030	COG1595	DNA-templated transcription, initiation
EXW63_09050	COG1695	Transcriptional regulator
EXW63_09055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW63_09060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW63_09065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW63_09070	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW63_09075	COG3620	sequence-specific DNA binding
EXW63_09085	COG2267	carboxylic ester hydrolase activity
EXW63_09095	COG0457	Tetratricopeptide repeat
EXW63_09100	COG0346	lactoylglutathione lyase activity
EXW63_09105	COG0346	lactoylglutathione lyase activity
EXW63_09115	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW63_09120	COG4717	serine-type aminopeptidase activity
EXW63_09125	COG0420	3'-5' exonuclease activity
EXW63_09155	COG2197	response regulator
EXW63_09160	COG4585	Histidine kinase
EXW63_09175	COG2186	Transcriptional regulator
EXW63_09180	COG2807	transmembrane transport
EXW63_09205	COG0825	malonyl-CoA metabolic process
EXW63_09260	COG2373	Large extracellular alpha-helical protein
EXW63_09270	COG0457	Tetratricopeptide repeat
EXW63_09285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW63_09305	COG1959	2 iron, 2 sulfur cluster binding
EXW63_09345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW63_09350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW63_09365	COG2376	Dihydroxyacetone kinase
EXW63_09385	COG2376	Dihydroxyacetone kinase
EXW63_09410	COG0640	Transcriptional regulator
EXW63_09415	COG2814	Major facilitator Superfamily
EXW63_09465	COG0477	Major facilitator Superfamily
EXW63_09475	COG1842	Phage shock protein A
EXW63_09510	COG0305	Participates in initiation and elongation during chromosome replication
EXW63_09525	COG0789	Transcriptional regulator
EXW63_09525	COG4978	Transcriptional regulator
EXW63_09570	COG3181	Tripartite tricarboxylate transporter family receptor
EXW63_09575	COG4565	transcriptional regulatory protein
EXW63_09580	COG3290	protein histidine kinase activity
EXW63_09585	COG0477	Major facilitator Superfamily
EXW63_09610	COG4608	Belongs to the ABC transporter superfamily
EXW63_09615	COG0444	Belongs to the ABC transporter superfamily
EXW63_09620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW63_09625	COG0601	transmembrane transport
EXW63_09650	COG2197	response regulator
EXW63_09670	COG0579	oxidoreductase
EXW63_09690	COG2318	DinB family
EXW63_09705	COG1363	Peptidase, m42
EXW63_09735	COG1024	Enoyl-CoA hydratase
EXW63_09755	COG2244	polysaccharide biosynthetic process
EXW63_09760	COG0659	secondary active sulfate transmembrane transporter activity
EXW63_09770	COG0318	PFAM AMP-dependent synthetase and ligase
EXW63_09775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW63_09780	COG3409	Peptidoglycan-binding domain 1 protein
EXW63_09780	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW63_09790	COG0561	phosphatase activity
EXW63_09795	COG2094	Belongs to the DNA glycosylase MPG family
EXW63_09800	COG1216	Glycosyl transferase, family 2
EXW63_09805	COG0463	Glycosyl transferase, family 2
EXW63_09810	COG3527	Alpha-acetolactate decarboxylase
EXW63_09815	COG0028	Belongs to the TPP enzyme family
EXW63_09830	COG3679	Belongs to the UPF0342 family
EXW63_09835	COG4399	Belongs to the UPF0754 family
EXW63_09845	COG0189	ligase activity
EXW63_09860	COG1126	abc transporter atp-binding protein
EXW63_09865	COG0765	amino acid transport
EXW63_09870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW63_09875	COG1132	(ABC) transporter
EXW63_09880	COG1132	(ABC) transporter
EXW63_09895	COG1012	belongs to the aldehyde dehydrogenase family
EXW63_09900	COG0531	amino acid
EXW63_09920	COG2211	Major facilitator Superfamily
EXW63_09925	COG4533	DNA binding
EXW63_09940	COG1733	regulation of RNA biosynthetic process
EXW63_09945	COG2814	Major facilitator Superfamily
EXW63_09950	COG1309	transcriptional regulator
EXW63_09955	COG2076	Multidrug Resistance protein
EXW63_09980	COG1522	sequence-specific DNA binding
EXW63_10005	COG2259	Doxx family
EXW63_10015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW63_10015	COG1263	PTS System
EXW63_10025	COG1737	Transcriptional regulator
EXW63_10035	COG0475	glutathione-regulated potassium exporter activity
EXW63_10040	COG0531	amino acid
EXW63_10070	COG0586	Pfam SNARE associated Golgi protein
EXW63_10100	COG3546	catalase activity
EXW63_10105	COG1114	Component of the transport system for branched-chain amino acids
EXW63_10120	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW63_10130	COG1136	(ABC) transporter
EXW63_10135	COG0577	efflux transmembrane transporter activity
EXW63_10140	COG1388	LysM domain
EXW63_10140	COG3584	3D domain protein
EXW63_10165	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW63_10170	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW63_10175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW63_10175	COG3711	transcriptional antiterminator
EXW63_10190	COG2814	Major facilitator Superfamily
EXW63_10195	COG0604	alcohol dehydrogenase
EXW63_10200	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW63_10220	COG1316	TRANSCRIPTIONal
EXW63_10230	COG0730	response to heat
EXW63_10235	COG2210	Belongs to the sulfur carrier protein TusA family
EXW63_10240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW63_10245	COG0425	Belongs to the sulfur carrier protein TusA family
EXW63_10245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW63_10250	COG0425	Belongs to the sulfur carrier protein TusA family
EXW63_10255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW63_10255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW63_10260	COG0425	Belongs to the sulfur carrier protein TusA family
EXW63_10260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW63_10265	COG1937	Protein conserved in bacteria
EXW63_10290	COG2719	SpoVR family
EXW63_10295	COG0778	Nitroreductase
EXW63_10355	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_10360	COG2252	PERMEase
EXW63_10365	COG1879	ABC-type sugar transport system periplasmic component
EXW63_10370	COG1129	ABC transporter
EXW63_10375	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW63_10395	COG1846	Transcriptional regulator
EXW63_10400	COG2814	Major facilitator Superfamily
EXW63_10405	COG2205	protein histidine kinase activity
EXW63_10410	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW63_10415	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW63_10420	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW63_10450	COG1136	(ABC) transporter
EXW63_10470	COG0351	phosphomethylpyrimidine kinase
EXW63_10475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW63_10480	COG2022	thiamine diphosphate biosynthetic process
EXW63_10485	COG2104	thiamine diphosphate biosynthetic process
EXW63_10490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW63_10495	COG0352	thiamine-phosphate diphosphorylase activity
EXW63_10500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW63_10505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW63_10510	COG1116	anion transmembrane transporter activity
EXW63_10515	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW63_10520	COG3103	Sh3 type 3 domain protein
EXW63_10520	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW63_10520	COG4991	sh3 domain protein
EXW63_10540	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW63_10660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW63_10670	COG0581	inorganic phosphate transmembrane transporter activity
EXW63_10675	COG0573	inorganic phosphate transmembrane transporter activity
EXW63_10680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW63_10690	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW63_10695	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW63_10705	COG0531	amino acid
EXW63_10710	COG0697	spore germination
EXW63_10715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW63_10730	COG4990	cell redox homeostasis
EXW63_10735	COG0833	amino acid
EXW63_10745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW63_10750	COG1845	cytochrome c oxidase, subunit III
EXW63_10765	COG0475	glutathione-regulated potassium exporter activity
EXW63_10765	COG0569	domain protein
EXW63_10785	COG3620	sequence-specific DNA binding
EXW63_10790	COG2252	PERMEase
EXW63_10795	COG1113	amino acid transport
EXW63_10810	COG1114	Component of the transport system for branched-chain amino acids
EXW63_10815	COG3104	oligopeptide transport
EXW63_10835	COG1476	TRANSCRIPTIONal
EXW63_10840	COG3583	domain protein
EXW63_10840	COG3584	3D domain protein
EXW63_10845	COG0840	transmembrane signaling receptor activity
EXW63_10890	COG1063	alcohol dehydrogenase
EXW63_10920	COG1879	ABC-type sugar transport system periplasmic component
EXW63_10925	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW63_10935	COG1869	D-ribose catabolic process
EXW63_10940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW63_10945	COG1609	Transcriptional regulator
EXW63_10950	COG0477	Major facilitator Superfamily
EXW63_10955	COG1846	Transcriptional regulator
EXW63_10960	COG2271	Major facilitator Superfamily
EXW63_10970	COG4608	Belongs to the ABC transporter superfamily
EXW63_10975	COG0601	transmembrane transport
EXW63_11000	COG0659	secondary active sulfate transmembrane transporter activity
EXW63_11015	COG5002	protein histidine kinase activity
EXW63_11020	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW63_11025	COG2378	regulation of single-species biofilm formation
EXW63_11050	COG0833	amino acid
EXW63_11055	COG0765	amino acid transport
EXW63_11060	COG0765	amino acid transport
EXW63_11065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW63_11070	COG1126	abc transporter atp-binding protein
EXW63_11075	COG1115	amino acid carrier protein
EXW63_11080	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW63_11090	COG0697	spore germination
EXW63_11105	COG0366	Alpha amylase catalytic
EXW63_11110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW63_11110	COG1263	PTS System
EXW63_11115	COG2188	Transcriptional regulator
EXW63_11120	COG0531	amino acid
EXW63_11140	COG0714	Associated with various cellular activities
EXW63_11145	COG4548	von Willebrand factor, type A
EXW63_11155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW63_11160	COG0156	8-amino-7-oxononanoate synthase activity
EXW63_11175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW63_11180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW63_11185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW63_11190	COG3104	oligopeptide transport
EXW63_11210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW63_11215	COG1620	l-lactate permease
EXW63_11220	COG1027	Aspartate ammonia-lyase
EXW63_11225	COG1253	flavin adenine dinucleotide binding
EXW63_11230	COG0346	lactoylglutathione lyase activity
EXW63_11235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW63_11240	COG1316	TRANSCRIPTIONal
EXW63_11245	COG2720	vancomycin resistance protein
EXW63_11265	COG3227	Zinc metalloprotease (Elastase)
EXW63_11275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW63_11280	COG2217	Heavy metal translocating P-type atpase
EXW63_11285	COG0640	Transcriptional regulator
EXW63_11295	COG0531	amino acid
EXW63_11310	COG2427	Protein of unknown function (DUF1641)
EXW63_11315	COG3383	formate dehydrogenase (NAD+) activity
EXW63_11320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW63_11325	COG0456	acetyltransferase
EXW63_11330	COG0745	RESPONSE REGULATOR receiver
EXW63_11335	COG5002	protein histidine kinase activity
EXW63_11345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW63_11350	COG0697	spore germination
EXW63_11360	COG0281	malic enzyme
EXW63_11365	COG3493	citrate carrier protein
EXW63_11370	COG4565	transcriptional regulatory protein
EXW63_11375	COG3290	protein histidine kinase activity
EXW63_11385	COG4990	cell redox homeostasis
EXW63_11395	COG5002	protein histidine kinase activity
EXW63_11400	COG0745	RESPONSE REGULATOR receiver
EXW63_11405	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW63_11415	COG0395	ABC-type sugar transport system, permease component
EXW63_11420	COG1175	transmembrane transport
EXW63_11425	COG3842	ATPase activity
EXW63_11430	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW63_11455	COG2851	Citrate transporter
EXW63_11460	COG4565	transcriptional regulatory protein
EXW63_11465	COG3290	protein histidine kinase activity
EXW63_11480	COG2268	Band 7 protein
EXW63_11485	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW63_11500	COG2718	Belongs to the UPF0229 family
EXW63_11505	COG2766	serine protein kinase
EXW63_11515	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW63_11535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW63_11540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW63_11660	COG0735	belongs to the Fur family
EXW63_11665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW63_11685	COG4555	ABC transporter
EXW63_11690	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW63_11695	COG0067	glutamate synthase
EXW63_11695	COG0069	glutamate synthase activity
EXW63_11695	COG0070	glutamate synthase
EXW63_11705	COG4129	membrane
EXW63_11710	COG1132	(ABC) transporter
EXW63_11715	COG3557	Belongs to the UPF0374 family
EXW63_11735	COG1194	a g-specific adenine glycosylase
EXW63_11740	COG1988	membrane-bound metal-dependent
EXW63_11765	COG2137	regulation of response to DNA damage stimulus
EXW63_11770	COG1090	epimerase
EXW63_11775	COG1228	amidohydrolase
EXW63_11790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW63_11795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW63_11810	COG0463	Glycosyl transferase, family 2
EXW63_11815	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW63_11815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW63_11825	COG1216	Glycosyl transferase, family 2
EXW63_11840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW63_11845	COG1263	PTS System
EXW63_11845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW63_11855	COG2066	Belongs to the glutaminase family
EXW63_11875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW63_11880	COG0833	amino acid
EXW63_11890	COG3829	transcription factor binding
EXW63_11910	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW63_11930	COG0535	radical SAM domain protein
EXW63_11940	COG0387	Pfam Sodium calcium exchanger
EXW63_11945	COG3871	stress protein (general stress protein 26)
EXW63_11960	COG0586	Pfam SNARE associated Golgi protein
EXW63_11985	COG0697	spore germination
EXW63_11990	COG2217	Heavy metal translocating P-type atpase
EXW63_11995	COG1295	ribonuclease BN
EXW63_12005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW63_12015	COG4840	Belongs to the UPF0435 family
EXW63_12025	COG3853	Toxic anion resistance protein (TelA)
EXW63_12035	COG0861	Integral membrane protein TerC family
EXW63_12040	COG2310	stress, protein
EXW63_12045	COG2310	stress, protein
EXW63_12050	COG2310	stress, protein
EXW63_12080	COG2270	Major facilitator Superfamily
EXW63_12130	COG0488	(ABC) transporter
EXW63_12135	COG1116	anion transmembrane transporter activity
EXW63_12140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW63_12145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW63_12165	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW63_12175	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW63_12195	COG1263	PTS System
EXW63_12195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW63_12195	COG2190	(PTS) system
EXW63_12200	COG0366	Alpha amylase catalytic
EXW63_12205	COG0277	FAD linked oxidase domain protein
EXW63_12220	COG0549	Belongs to the carbamate kinase family
EXW63_12245	COG0840	transmembrane signaling receptor activity
EXW63_12255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW63_12260	COG0765	amino acid transport
EXW63_12270	COG0723	plastoquinol--plastocyanin reductase activity
EXW63_12270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW63_12275	COG3541	Predicted nucleotidyltransferase
EXW63_12295	COG5002	protein histidine kinase activity
EXW63_12320	COG0166	Belongs to the GPI family
EXW63_12330	COG0492	ferredoxin-NADP+ reductase activity
EXW63_12335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW63_12340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW63_12345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW63_12355	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW63_12365	COG0450	alkyl hydroperoxide reductase
EXW63_12385	COG1473	amidohydrolase
EXW63_12390	COG1757	Na H antiporter
EXW63_12415	COG4807	Protein conserved in bacteria
EXW63_12420	COG5002	protein histidine kinase activity
EXW63_12425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW63_12435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW63_12450	COG2309	aminopeptidase activity
EXW63_12455	COG2076	Multidrug Resistance protein
EXW63_12460	COG1012	belongs to the aldehyde dehydrogenase family
EXW63_12470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW63_12475	COG0546	phosphoglycolate phosphatase activity
EXW63_12480	COG1597	lipid kinase activity
EXW63_12485	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW63_12490	COG0154	amidase activity
EXW63_12500	COG4682	membrane
EXW63_12505	COG1846	Transcriptional regulator
EXW63_12510	COG0003	Pfam Anion-transporting ATPase
EXW63_12525	COG1464	Belongs to the NlpA lipoprotein family
EXW63_12530	COG2011	ABC-type metal ion transport system permease component
EXW63_12540	COG1335	isochorismatase
EXW63_12545	COG1012	belongs to the aldehyde dehydrogenase family
EXW63_12555	COG4851	CamS sex pheromone cAM373 precursor
EXW63_12560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW63_12565	COG0210	DNA helicase
EXW63_12570	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW63_12595	COG0151	Belongs to the GarS family
EXW63_12600	COG0138	bifunctional purine biosynthesis protein purh
EXW63_12605	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW63_12610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW63_12615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW63_12620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW63_12625	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW63_12630	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW63_12635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW63_12640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW63_12645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW63_12650	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW63_12675	COG0697	spore germination
EXW63_12700	COG0745	RESPONSE REGULATOR receiver
EXW63_12705	COG2205	protein histidine kinase activity
EXW63_12760	COG0693	protein deglycase activity
EXW63_12785	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW63_12810	COG5002	protein histidine kinase activity
EXW63_12820	COG2252	PERMEase
EXW63_12825	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW63_12825	COG0519	Catalyzes the synthesis of GMP from XMP
EXW63_12830	COG0459	protein refolding
EXW63_12835	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW63_12840	COG1266	CAAX protease self-immunity
EXW63_12850	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW63_12855	COG0488	(ABC) transporter
EXW63_12865	COG0456	acetyltransferase
EXW63_12870	COG1214	PFAM Peptidase M22, glycoprotease
EXW63_12875	COG0802	atpase or kinase
EXW63_12975	COG2183	response to ionizing radiation
EXW63_12980	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW63_12985	COG0864	Transcriptional regulator
EXW63_12990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW63_12995	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW63_13000	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW63_13005	COG0705	Rhomboid family
EXW63_13010	COG4294	response to UV
EXW63_13020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW63_13030	COG2814	Major facilitator Superfamily
EXW63_13035	COG0531	amino acid
EXW63_13045	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW63_13050	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW63_13080	COG0561	phosphatase activity
EXW63_13085	COG4608	Belongs to the ABC transporter superfamily
EXW63_13090	COG0444	Belongs to the ABC transporter superfamily
EXW63_13095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW63_13100	COG0601	transmembrane transport
EXW63_13110	COG0747	negative chemotaxis
EXW63_13120	COG0488	(ABC) transporter
EXW63_13145	COG5298	Protein conserved in bacteria
EXW63_13165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW63_13175	COG1609	Transcriptional regulator
EXW63_13185	COG0204	Acyl-transferase
EXW63_13200	COG0697	spore germination
EXW63_13215	COG1910	domain protein
EXW63_13220	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW63_13225	COG4149	molybdate abc transporter
EXW63_13240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW63_13245	COG0656	L-ascorbic acid biosynthetic process
EXW63_13250	COG4166	transmembrane transport
EXW63_13255	COG4166	transmembrane transport
EXW63_13270	COG2207	Transcriptional regulator
EXW63_13280	COG4166	transmembrane transport
EXW63_13285	COG4608	Belongs to the ABC transporter superfamily
EXW63_13290	COG0444	Belongs to the ABC transporter superfamily
EXW63_13295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW63_13300	COG0601	transmembrane transport
EXW63_13320	COG2814	Major facilitator Superfamily
EXW63_13330	COG2271	Major facilitator Superfamily
EXW63_13335	COG0277	FAD linked oxidase domain protein
EXW63_13350	COG1464	Belongs to the NlpA lipoprotein family
EXW63_13360	COG2011	ABC-type metal ion transport system permease component
EXW63_13365	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_13390	COG1506	peptidase
EXW63_13390	COG0823	Involved in the tonB-independent uptake of proteins
EXW63_13390	COG4946	Tricorn protease homolog
EXW63_13410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW63_13415	COG4856	YbbR-like protein
EXW63_13420	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW63_13500	COG0726	polysaccharide deacetylase
EXW63_13505	COG2194	sulfuric ester hydrolase activity
EXW63_13515	COG0489	protein tyrosine kinase activity
EXW63_13520	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW63_13530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW63_13535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW63_13545	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW63_13570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW63_13575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW63_13580	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW63_13590	COG0024	Methionine aminopeptidase
EXW63_13595	COG0563	adenylate kinase activity
EXW63_13600	COG0201	protein transport
EXW63_13605	COG0200	Binds to the 23S rRNA
EXW63_13610	COG1841	ribosomal large subunit assembly
EXW63_13620	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW63_13630	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW63_13640	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW63_13645	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW63_13655	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW63_13660	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW63_13675	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW63_13680	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW63_13685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW63_13690	COG0089	rRNA binding
EXW63_13695	COG0088	Forms part of the polypeptide exit tunnel
EXW63_13700	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW63_13705	COG0051	transcription antitermination factor activity, RNA binding
EXW63_13710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW63_13715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW63_13725	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW63_13730	COG1358	cellular component organization or biogenesis
EXW63_13735	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW63_13740	COG0085	RNA polymerase activity
EXW63_13745	COG2813	Specifically methylates the guanine in position
EXW63_13750	COG0222	ribosome binding
EXW63_13755	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW63_13760	COG0081	regulation of translation
EXW63_13765	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW63_13770	COG0250	Participates in transcription elongation, termination and antitermination
EXW63_13775	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW63_13780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW63_13790	COG3688	RNA-binding protein containing a PIN domain
EXW63_13795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW63_13805	COG0215	cysteine-tRNA ligase activity
EXW63_13810	COG1045	serine acetyltransferase
EXW63_13815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW63_13825	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW63_13830	COG4956	integral membrane protein (PIN domain superfamily)
EXW63_13835	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW63_13840	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW63_13845	COG0542	response to heat
EXW63_13850	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW63_13855	COG3880	PFAM UvrB UvrC protein
EXW63_13945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW63_13950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW63_13955	COG1396	sequence-specific DNA binding
EXW63_13960	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW63_13965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW63_13970	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW63_13975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW63_13980	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW63_13985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW63_13990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW63_13995	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW63_14000	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW63_14005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW63_14010	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW63_14020	COG2208	phosphoserine phosphatase activity
EXW63_14035	COG1098	S1 RNA binding domain
EXW63_14055	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW63_14060	COG3956	TIGRFAM MazG family protein
EXW63_14065	COG2244	polysaccharide biosynthetic process
EXW63_14070	COG2002	toxin-antitoxin pair type II binding
EXW63_14075	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW63_14095	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW63_14100	COG2088	sporulation resulting in formation of a cellular spore
EXW63_14105	COG0251	oxidation-reduction process
EXW63_14110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW63_14115	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW63_14125	COG4466	Protein conserved in bacteria
EXW63_14135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW63_14145	COG0084	hydrolase, TatD family'
EXW63_14155	COG2002	toxin-antitoxin pair type II binding
EXW63_14160	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW63_14170	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW63_14175	COG4467	Involved in initiation control of chromosome replication
EXW63_14180	COG1774	PSP1 C-terminal conserved region
EXW63_14185	COG0470	DNA polymerase III
EXW63_14190	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW63_14195	COG1982	Orn Lys Arg decarboxylase major
EXW63_14240	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW63_14245	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW63_14250	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW63_14260	COG0590	tRNA wobble adenosine to inosine editing
EXW63_14265	COG1335	isochorismatase
EXW63_14270	COG1428	Deoxynucleoside kinase
EXW63_14275	COG1428	Deoxynucleoside kinase
EXW63_14295	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW63_14300	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW63_14305	COG1686	Belongs to the peptidase S11 family
EXW63_14310	COG0517	IMP dehydrogenase activity
EXW63_14310	COG0516	GMP reductase activity
EXW63_14345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW63_14350	COG0187	DNA topoisomerase II activity
EXW63_14355	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW63_14360	COG2501	S4 domain
EXW63_14365	COG0592	DNA-directed DNA polymerase activity
EXW63_14370	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW63_14375	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW63_14380	COG0594	ribonuclease P activity
EXW63_14385	COG0706	membrane insertase activity
EXW63_14390	COG1847	R3H domain protein
EXW63_14395	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW63_14400	COG0445	tRNA wobble uridine modification
EXW63_14405	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW63_14410	COG1475	DNA binding
EXW63_14415	COG1192	Involved in chromosome partitioning
EXW63_14420	COG1475	DNA binding
EXW63_14430	COG0668	transmembrane transport
EXW63_14435	COG4481	Protein conserved in bacteria
EXW63_14440	COG0012	GTP binding
EXW63_14445	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW63_14450	COG0629	single-stranded DNA binding
EXW63_14460	COG4241	membrane
EXW63_14465	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW63_14470	COG0359	binds to the 23S rRNA
EXW63_14475	COG0305	Participates in initiation and elongation during chromosome replication
EXW63_14505	COG0745	RESPONSE REGULATOR receiver
EXW63_14510	COG5002	protein histidine kinase activity
EXW63_14520	COG4853	Protein conserved in bacteria
EXW63_14525	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW63_14530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW63_14540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW63_14550	COG1164	Oligoendopeptidase f
EXW63_14580	COG1272	protein, Hemolysin III
EXW63_14585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW63_14635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW63_14645	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW63_14650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW63_14655	COG2814	Major facilitator Superfamily
EXW63_14660	COG3275	phosphorelay sensor kinase activity
EXW63_14665	COG3279	Response regulator of the LytR AlgR family
EXW63_14670	COG1380	Effector of murein hydrolase LrgA
EXW63_14680	COG0628	permease
EXW63_14685	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW63_14685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW63_14690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW63_14695	COG1309	transcriptional regulator
EXW63_14700	COG0463	Glycosyl transferase, family 2
EXW63_14715	COG0488	(ABC) transporter
EXW63_14720	COG1216	Glycosyl transferase, family 2
EXW63_14730	COG1607	acyl-coa hydrolase
EXW63_14740	COG0840	transmembrane signaling receptor activity
EXW63_14770	COG0477	Major facilitator Superfamily
EXW63_14775	COG3279	Response regulator of the LytR AlgR family
EXW63_14780	COG1966	Carbon starvation protein
EXW63_14785	COG2879	small protein
EXW63_14790	COG3706	GGDEF domain
EXW63_14795	COG0351	phosphomethylpyrimidine kinase
EXW63_14800	COG4585	Histidine kinase
EXW63_14800	COG2203	Gaf domain
EXW63_14805	COG2197	response regulator
EXW63_14820	COG2873	o-acetylhomoserine
EXW63_14825	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW63_14830	COG0460	homoserine dehydrogenase
EXW63_14840	COG1609	Transcriptional regulator
EXW63_14845	COG2755	lipolytic protein G-D-S-L family
EXW63_14850	COG1131	(ABC) transporter
EXW63_14855	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW63_14860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW63_14865	COG2814	Major facilitator Superfamily
EXW63_14870	COG0561	phosphatase activity
EXW63_14875	COG2233	PERMEase
EXW63_14890	COG2363	Small membrane protein
EXW63_14900	COG3773	Cell wall hydrolase
EXW63_14910	COG3253	May function as heme-dependent peroxidase
EXW63_14915	COG0280	phosphate acetyltransferase
EXW63_14935	COG4844	belongs to the
EXW63_14940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW63_14945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW63_14950	COG1120	ATPase activity
EXW63_14955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW63_14960	COG1078	dGTPase activity
EXW63_14970	COG1994	Peptidase M50
EXW63_14980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW63_14985	COG0584	glycerophosphoryl diester phosphodiesterase
EXW63_14990	COG0789	Transcriptional regulator
EXW63_14995	COG2814	Major facilitator Superfamily
EXW63_15000	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW63_15005	COG0010	Belongs to the arginase family
EXW63_15025	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW63_15030	COG4506	Protein conserved in bacteria
EXW63_15045	COG2234	aminopeptidase activity
EXW63_15055	COG0024	Methionine aminopeptidase
EXW63_15060	COG1131	(ABC) transporter
EXW63_15065	COG0842	Transport permease protein
EXW63_15070	COG4585	Histidine kinase
EXW63_15075	COG2197	response regulator
EXW63_15100	COG3300	MHYT domain
EXW63_15100	COG5001	Diguanylate cyclase
EXW63_15105	COG4294	response to UV
EXW63_15110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW63_15115	COG0247	lactate metabolic process
EXW63_15115	COG2181	nitrate reductase activity
EXW63_15120	COG0183	Belongs to the thiolase family
EXW63_15125	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW63_15130	COG1960	acyl-CoA dehydrogenase activity
EXW63_15135	COG1960	acyl-CoA dehydrogenase activity
EXW63_15145	COG3343	RNA polymerase activity
EXW63_15150	COG0504	CTP synthase activity
EXW63_15155	COG4821	SIS domain
EXW63_15175	COG1494	fructose-1,6-bisphosphatase
EXW63_15180	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW63_15195	COG1435	thymidine kinase activity
EXW63_15205	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW63_15210	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW63_15225	COG0009	L-threonylcarbamoyladenylate synthase
EXW63_15230	COG1971	Probably functions as a manganese efflux pump
EXW63_15240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW63_15245	COG2259	Doxx family
EXW63_15250	COG2190	(PTS) system
EXW63_15260	COG0698	ribose 5-phosphate isomerase
EXW63_15270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW63_15295	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW63_15305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW63_15310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW63_15315	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW63_15320	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW63_15325	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW63_15330	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW63_15345	COG5001	Diguanylate cyclase
EXW63_15345	COG3300	MHYT domain
EXW63_15350	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW63_15355	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW63_15360	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW63_15365	COG0649	NAD binding
EXW63_15370	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW63_15380	COG0839	Belongs to the complex I subunit 6 family
EXW63_15385	COG0713	ATP synthesis coupled electron transport
EXW63_15390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW63_15395	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW63_15400	COG1007	ATP synthesis coupled electron transport
EXW63_15405	COG4836	Membrane
EXW63_15420	COG2385	sporulation resulting in formation of a cellular spore
EXW63_15425	COG3279	Response regulator of the LytR AlgR family
EXW63_15440	COG0739	heme binding
EXW63_15455	COG1609	Transcriptional regulator
EXW63_15470	COG0489	protein tyrosine kinase activity
EXW63_15475	COG3944	biosynthesis protein
EXW63_15480	COG0489	protein tyrosine kinase activity
EXW63_15485	COG4464	protein tyrosine phosphatase activity
EXW63_15490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW63_15495	COG1086	Polysaccharide biosynthesis protein
EXW63_15500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW63_15510	COG1086	Polysaccharide biosynthesis protein
EXW63_15520	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW63_15530	COG0438	transferase activity, transferring glycosyl groups
EXW63_15550	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW63_15555	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EXW63_15565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EXW63_15575	COG1316	TRANSCRIPTIONal
EXW63_15600	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW63_15615	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW63_15630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW63_15635	COG0745	RESPONSE REGULATOR receiver
EXW63_15640	COG3850	Histidine kinase
EXW63_15640	COG5002	protein histidine kinase activity
EXW63_15655	COG2271	Major facilitator Superfamily
EXW63_15675	COG1136	(ABC) transporter
EXW63_15680	COG0577	efflux transmembrane transporter activity
EXW63_15725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW63_15730	COG4715	Zinc finger, swim domain protein
EXW63_15755	COG3584	3D domain protein
EXW63_15755	COG1388	LysM domain
EXW63_15765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW63_15770	COG1215	transferase activity, transferring glycosyl groups
EXW63_15780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW63_15785	COG0791	NLP P60 protein
EXW63_15785	COG1388	LysM domain
EXW63_15795	COG1368	sulfuric ester hydrolase activity
EXW63_15810	COG2389	metal-binding protein
EXW63_15820	COG1620	l-lactate permease
EXW63_15825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW63_15830	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW63_15835	COG1294	oxidase, subunit
EXW63_15840	COG1271	oxidase subunit
EXW63_15845	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW63_15850	COG0583	DNA-binding transcription factor activity
EXW63_15855	COG1511	domain protein
EXW63_15870	COG1301	dicarboxylic acid transport
EXW63_15875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW63_15885	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW63_15895	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW63_15905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW63_15910	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW63_15915	COG1486	melibiose metabolic process
EXW63_15935	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW63_15935	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW63_15945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW63_15950	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW63_15955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW63_15960	COG1316	TRANSCRIPTIONal
EXW63_15965	COG1739	Uncharacterized protein family UPF0029
EXW63_15970	COG1307	EDD domain protein, DegV family
EXW63_15975	COG1733	regulation of RNA biosynthetic process
EXW63_15980	COG1388	LysM domain
EXW63_15980	COG0791	NLP P60 protein
EXW63_15985	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW63_15990	COG1040	competence protein
EXW63_15995	COG1278	Cold shock
EXW63_16030	COG1131	(ABC) transporter
EXW63_16065	COG2884	Cell division ATP-binding protein ftsE
EXW63_16070	COG2177	Part of the ABC transporter FtsEX involved in
EXW63_16075	COG0793	Belongs to the peptidase S41A family
EXW63_16075	COG3409	Peptidoglycan-binding domain 1 protein
EXW63_16080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW63_16085	COG1132	(ABC) transporter
EXW63_16095	COG0488	(ABC) transporter
EXW63_16100	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW63_16105	COG0789	Transcriptional regulator
EXW63_16110	COG0583	DNA-binding transcription factor activity
EXW63_16145	COG0789	Transcriptional regulator
EXW63_16165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW63_16170	COG1950	PFAM Membrane protein of
EXW63_16175	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW63_16180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW63_16185	COG0546	phosphoglycolate phosphatase activity
EXW63_16190	COG0110	maltose O-acetyltransferase activity
EXW63_16195	COG0457	Tetratricopeptide repeat
EXW63_16200	COG0492	ferredoxin-NADP+ reductase activity
EXW63_16210	COG1051	belongs to the nudix hydrolase family
EXW63_16215	COG1660	Displays ATPase and GTPase activities
EXW63_16220	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW63_16225	COG1481	regulation of sporulation
EXW63_16230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW63_16245	COG2323	membrane
EXW63_16260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW63_16290	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW63_16305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW63_16310	COG0126	phosphoglycerate kinase activity
EXW63_16315	COG0149	triose-phosphate isomerase activity
EXW63_16325	COG0148	phosphopyruvate hydratase activity
EXW63_16340	COG1346	cytolysis
EXW63_16345	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW63_16350	COG1647	Serine aminopeptidase, S33
EXW63_16355	COG0557	exoribonuclease II activity
EXW63_16365	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW63_16405	COG2233	PERMEase
EXW63_16410	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW63_16415	COG0288	reversible hydration of carbon dioxide
EXW63_16420	COG1522	sequence-specific DNA binding
EXW63_16430	COG1522	sequence-specific DNA binding
EXW63_16435	COG1335	isochorismatase
EXW63_16440	COG4224	UPF0291 protein
EXW63_16455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW63_16475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW63_16490	COG0840	transmembrane signaling receptor activity
EXW63_16490	COG3290	protein histidine kinase activity
EXW63_16510	COG1252	NADH dehydrogenase
EXW63_16520	COG1733	regulation of RNA biosynthetic process
EXW63_16525	COG2814	Major facilitator Superfamily
EXW63_16530	COG0656	L-ascorbic acid biosynthetic process
EXW63_16550	COG2910	NAD(P)H-binding
EXW63_16555	COG1115	amino acid carrier protein
EXW63_16560	COG1115	amino acid carrier protein
EXW63_16565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW63_16570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW63_16575	COG2311	Membrane
EXW63_16580	COG1528	Iron-storage protein
EXW63_16590	COG1611	Belongs to the LOG family
EXW63_16600	COG2318	DinB family
EXW63_16610	COG0783	Belongs to the Dps family
EXW63_16620	COG1115	amino acid carrier protein
EXW63_16625	COG0490	domain, Protein
EXW63_16630	COG0475	glutathione-regulated potassium exporter activity
EXW63_16635	COG0586	Pfam SNARE associated Golgi protein
EXW63_16650	COG1741	Belongs to the pirin family
EXW63_16655	COG3227	Zinc metalloprotease (Elastase)
EXW63_16660	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW63_16665	COG0840	transmembrane signaling receptor activity
EXW63_16670	COG0840	transmembrane signaling receptor activity
EXW63_16680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW63_16690	COG5002	protein histidine kinase activity
EXW63_16695	COG0745	RESPONSE REGULATOR receiver
EXW63_16700	COG1376	ErfK ybiS ycfS ynhG family protein
EXW63_16710	COG0586	Pfam SNARE associated Golgi protein
EXW63_16740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW63_16765	COG0531	amino acid
EXW63_16770	COG2814	Major facilitator Superfamily
EXW63_16785	COG0840	transmembrane signaling receptor activity
EXW63_16790	COG0011	TIGRFAM Protein of
EXW63_16800	COG0506	proline dehydrogenase activity
EXW63_16805	COG1686	Belongs to the peptidase S11 family
EXW63_16815	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW63_16815	COG1024	Enoyl-CoA hydratase
EXW63_16820	COG0183	Belongs to the thiolase family
EXW63_16825	COG1960	acyl-CoA dehydrogenase activity
EXW63_16830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW63_16835	COG1309	transcriptional regulator
EXW63_16880	COG1393	Belongs to the ArsC family
EXW63_16885	COG0509	glycine decarboxylation via glycine cleavage system
EXW63_16890	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW63_16895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW63_16905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW63_16910	COG2011	ABC-type metal ion transport system permease component
EXW63_16915	COG1464	Belongs to the NlpA lipoprotein family
EXW63_16920	COG1464	Belongs to the NlpA lipoprotein family
EXW63_16925	COG0396	ATPase activity
EXW63_16930	COG0719	Fe-S assembly protein
EXW63_16935	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW63_16940	COG0822	iron-sulfur transferase activity
EXW63_16945	COG0719	Fe-S assembly protein
EXW63_16955	COG1695	Transcriptional regulator
EXW63_16960	COG0737	Belongs to the 5'-nucleotidase family
EXW63_16965	COG3377	Domain of unknown function (DUF1805)
EXW63_16975	COG0739	heme binding
EXW63_16980	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW63_17000	COG4377	Putative membrane peptidase family (DUF2324)
EXW63_17005	COG0789	Transcriptional regulator
EXW63_17015	COG4470	Protein conserved in bacteria
EXW63_17030	COG1494	fructose-1,6-bisphosphatase
EXW63_17035	COG2445	Protein of unknown function DUF86
EXW63_17045	COG0647	UMP catabolic process
EXW63_17055	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW63_17080	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW63_17085	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW63_17095	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW63_17100	COG4837	Protein of unknown function (DUF1462)
EXW63_17135	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW63_17140	COG0390	transport system, permease component
EXW63_17150	COG1252	NADH dehydrogenase
EXW63_17155	COG4844	belongs to the
EXW63_17160	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW63_17165	COG0316	Belongs to the HesB IscA family
EXW63_17190	COG1683	Conserved Protein
EXW63_17210	COG0492	ferredoxin-NADP+ reductase activity
EXW63_17215	COG1252	NADH dehydrogenase
EXW63_17230	COG3584	3D domain protein
EXW63_17235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW63_17245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW63_17250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW63_17255	COG1268	BioY protein
EXW63_17265	COG2050	protein possibly involved in aromatic compounds catabolism
EXW63_17285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW63_17290	COG5018	Exonuclease
EXW63_17305	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW63_17315	COG2267	carboxylic ester hydrolase activity
EXW63_17320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW63_17325	COG1522	sequence-specific DNA binding
EXW63_17330	COG0436	Aminotransferase
EXW63_17335	COG1098	S1 RNA binding domain
EXW63_17340	COG2155	Conserved Protein
EXW63_17350	COG0166	Belongs to the GPI family
EXW63_17360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW63_17365	COG1285	pathogenesis
EXW63_17500	COG1309	transcriptional regulator
EXW63_17515	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW63_17520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW63_17525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW63_17535	COG0058	SHG alpha-glucan phosphorylase activity
EXW63_17555	COG1278	Cold shock
EXW63_17560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW63_17565	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW63_17570	COG1169	isochorismate synthase
EXW63_17575	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW63_17580	COG0596	Alpha beta hydrolase
EXW63_17585	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW63_17590	COG0318	PFAM AMP-dependent synthetase and ligase
EXW63_17595	COG4948	Mandelate Racemase Muconate Lactonizing
EXW63_17615	COG3964	amidohydrolase
EXW63_17635	COG2188	Transcriptional regulator
EXW63_17650	COG0577	efflux transmembrane transporter activity
EXW63_17655	COG1136	(ABC) transporter
EXW63_17660	COG0577	efflux transmembrane transporter activity
EXW63_17665	COG0577	efflux transmembrane transporter activity
EXW63_17670	COG2205	protein histidine kinase activity
EXW63_17675	COG0745	RESPONSE REGULATOR receiver
EXW63_17680	COG0640	Transcriptional regulator
EXW63_17685	COG5658	integral membrane protein
EXW63_17690	COG1131	(ABC) transporter
EXW63_17700	COG2207	Transcriptional regulator
EXW63_17700	COG3708	Transcriptional regulator
EXW63_17705	COG1136	(ABC) transporter
EXW63_17710	COG0577	efflux transmembrane transporter activity
EXW63_17725	COG0586	Pfam SNARE associated Golgi protein
EXW63_17735	COG5002	protein histidine kinase activity
EXW63_17765	COG1136	(ABC) transporter
EXW63_17780	COG1597	lipid kinase activity
EXW63_17785	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW63_17810	COG0745	RESPONSE REGULATOR receiver
EXW63_17815	COG5002	protein histidine kinase activity
EXW63_17845	COG1842	Phage shock protein A
EXW63_17870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW63_17890	COG1294	oxidase, subunit
EXW63_17895	COG1271	oxidase subunit
EXW63_17900	COG0288	reversible hydration of carbon dioxide
EXW63_17910	COG1854	S-ribosylhomocysteine lyase activity
EXW63_17915	COG0789	Transcriptional regulator
EXW63_17920	COG2076	Multidrug Resistance protein
EXW63_17925	COG2076	Multidrug Resistance protein
EXW63_17970	COG0494	nUDIX hydrolase
EXW63_17995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW63_18000	COG1116	anion transmembrane transporter activity
EXW63_18005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW63_18020	COG4895	conserved protein (DUF2196)
EXW63_18025	COG1368	sulfuric ester hydrolase activity
EXW63_18030	COG2267	carboxylic ester hydrolase activity
EXW63_18035	COG0753	catalase activity
EXW63_18040	COG3852	Histidine kinase
EXW63_18045	COG5002	protein histidine kinase activity
EXW63_18070	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW63_18075	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW63_18100	COG0438	transferase activity, transferring glycosyl groups
EXW63_18105	COG0671	phosphoesterase, PA-phosphatase related
EXW63_18110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW63_18115	COG2267	carboxylic ester hydrolase activity
EXW63_18130	COG1794	racemase activity, acting on amino acids and derivatives
EXW63_18140	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW63_18145	COG1242	4 iron, 4 sulfur cluster binding
EXW63_18165	COG1136	(ABC) transporter
EXW63_18180	COG0582	viral genome integration into host DNA
EXW63_18185	COG0490	domain, Protein
EXW63_18190	COG0475	glutathione-regulated potassium exporter activity
EXW63_18195	COG2814	Major facilitator Superfamily
EXW63_18200	COG0495	leucyl-tRNA aminoacylation
EXW63_18240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW63_18250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW63_18275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW63_18280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW63_18285	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW63_18290	COG0303	'Molybdopterin
EXW63_18295	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW63_18300	COG0314	molybdopterin synthase activity
EXW63_18325	COG1329	Transcriptional regulator
EXW63_18345	COG3832	glyoxalase III activity
EXW63_18355	COG2814	Major facilitator Superfamily
EXW63_18360	COG2081	HI0933 family
EXW63_18365	COG2244	polysaccharide biosynthetic process
EXW63_18370	COG1187	pseudouridine synthase activity
EXW63_18375	COG1349	DNA-binding transcription factor activity
EXW63_18380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW63_18390	COG1523	belongs to the glycosyl hydrolase 13 family
EXW63_18395	COG0510	thiamine kinase activity
EXW63_18405	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW63_18410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW63_18420	COG1363	Peptidase, m42
EXW63_18425	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW63_18430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW63_18435	COG4848	Belongs to the UPF0354 family
EXW63_18440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW63_18455	COG1674	ftsk spoiiie
EXW63_18465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW63_18470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW63_18495	COG2309	aminopeptidase activity
EXW63_18505	COG3118	belongs to the thioredoxin family
EXW63_18510	COG4851	CamS sex pheromone cAM373 precursor
EXW63_18515	COG1605	Chorismate mutase
EXW63_18515	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW63_18525	COG1609	Transcriptional regulator
EXW63_18550	COG1970	mechanosensitive ion channel activity
EXW63_18560	COG0666	response to abiotic stimulus
EXW63_18565	COG5002	protein histidine kinase activity
EXW63_18570	COG0745	RESPONSE REGULATOR receiver
EXW63_18585	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW63_18590	COG0517	IMP dehydrogenase activity
EXW63_18595	COG0454	-acetyltransferase
EXW63_18600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW63_18605	COG0110	maltose O-acetyltransferase activity
EXW63_18615	COG1595	DNA-templated transcription, initiation
EXW63_18640	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW63_18645	COG0626	cystathionine gamma-synthase activity
EXW63_18650	COG1956	GAF domain-containing protein
EXW63_18655	COG1309	transcriptional regulator
EXW63_18670	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW63_18675	COG1104	cysteine desulfurase activity
EXW63_18690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW63_18700	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW63_18715	COG3874	Sporulation protein YtfJ
EXW63_18720	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW63_18725	COG0827	DNA restriction-modification system
EXW63_18730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW63_18745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW63_18760	COG0137	argininosuccinate synthase activity
EXW63_18765	COG0165	Argininosuccinate lyase
EXW63_18785	COG0589	response to stress
EXW63_18790	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_18805	COG1476	TRANSCRIPTIONal
EXW63_18815	COG0662	Cupin 2, conserved barrel domain protein
EXW63_18860	COG0006	proline dipeptidase activity
EXW63_18865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW63_18870	COG4109	DRTGG domain
EXW63_18890	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW63_18905	COG0587	DNA-directed DNA polymerase activity
EXW63_18910	COG0281	malic enzyme
EXW63_18915	COG1725	Transcriptional regulator
EXW63_18920	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW63_18930	COG0205	6-phosphofructokinase activity
EXW63_18940	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW63_18945	COG0628	permease
EXW63_18965	COG0372	Belongs to the citrate synthase family
EXW63_18970	COG0538	isocitrate dehydrogenase activity
EXW63_18975	COG0039	L-malate dehydrogenase activity
EXW63_18990	COG0745	RESPONSE REGULATOR receiver
EXW63_18995	COG5002	protein histidine kinase activity
EXW63_19000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW63_19000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW63_19010	COG1971	Probably functions as a manganese efflux pump
EXW63_19015	COG0237	dephospho-CoA kinase activity
EXW63_19020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW63_19025	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW63_19030	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW63_19035	COG3611	Membrane attachment protein
EXW63_19040	COG1484	DNA-dependent DNA replication
EXW63_19050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW63_19065	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW63_19075	COG1363	Peptidase, m42
EXW63_19080	COG1309	transcriptional regulator
EXW63_19085	COG1566	PFAM secretion protein HlyD family protein
EXW63_19090	COG2814	Major facilitator Superfamily
EXW63_19120	COG1418	mRNA catabolic process
EXW63_19135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW63_19140	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW63_19165	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW63_19170	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW63_19175	COG1286	toxin biosynthetic process
EXW63_19180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW63_19180	COG1796	DNA polymerase
EXW63_19185	COG1193	negative regulation of DNA recombination
EXW63_19195	COG1114	Component of the transport system for branched-chain amino acids
EXW63_19200	COG5386	Cell surface protein
EXW63_19210	COG5386	Cell surface protein
EXW63_19225	COG1120	ATPase activity
EXW63_19230	COG4509	Sortase family
EXW63_19235	COG2329	Antibiotic biosynthesis monooxygenase
EXW63_19240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW63_19245	COG4895	conserved protein (DUF2196)
EXW63_19250	COG0745	RESPONSE REGULATOR receiver
EXW63_19255	COG2205	protein histidine kinase activity
EXW63_19260	COG1131	(ABC) transporter
EXW63_19285	COG2318	DinB family
EXW63_19310	COG0318	PFAM AMP-dependent synthetase and ligase
EXW63_19315	COG1309	transcriptional regulator
EXW63_19320	COG1024	Enoyl-CoA hydratase
EXW63_19325	COG2086	electron transfer activity
EXW63_19330	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW63_19335	COG3118	belongs to the thioredoxin family
EXW63_19340	COG0322	excinuclease ABC activity
EXW63_19345	COG1719	4-vinyl reductase, 4VR
EXW63_19350	COG2009	succinate dehydrogenase
EXW63_19355	COG1053	succinate dehydrogenase
EXW63_19360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW63_19365	COG0824	Thioesterase
EXW63_19370	COG1876	peptidase activity
EXW63_19380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW63_19385	COG1360	Flagellar Motor Protein
EXW63_19390	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW63_19395	COG4152	abc transporter atp-binding protein
EXW63_19400	COG1668	transmembrane transport
EXW63_19405	COG1959	2 iron, 2 sulfur cluster binding
EXW63_19415	COG0697	spore germination
EXW63_19420	COG1396	sequence-specific DNA binding
EXW63_19425	COG1983	PspC domain protein
EXW63_19430	COG0402	S-adenosylhomocysteine deaminase activity
EXW63_19435	COG2233	PERMEase
EXW63_19440	COG2197	response regulator
EXW63_19450	COG1309	transcriptional regulator
EXW63_19460	COG0477	Major facilitator Superfamily
EXW63_19470	COG5401	PFAM Sporulation and spore germination
EXW63_19475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW63_19485	COG0622	Phosphoesterase
EXW63_19515	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW63_19525	COG1067	ATP-dependent peptidase activity
EXW63_19525	COG0470	DNA polymerase III
EXW63_19535	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW63_19540	COG1764	response to oxidative stress
EXW63_19545	COG1846	Transcriptional regulator
EXW63_19550	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW63_19555	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW63_19560	COG0181	hydroxymethylbilane synthase activity
EXW63_19565	COG1587	Uroporphyrinogen-III synthase
EXW63_19570	COG0113	porphobilinogen synthase activity
EXW63_19575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW63_19580	COG1388	LysM domain
EXW63_19595	COG0285	dihydrofolate synthase activity
EXW63_19610	COG0424	maF-like protein
EXW63_19615	COG2003	Belongs to the UPF0758 family
EXW63_19620	COG1077	Cell shape determining protein MreB Mrl
EXW63_19635	COG0850	regulation of cytokinetic process
EXW63_19640	COG2894	cell division
EXW63_19645	COG0739	heme binding
EXW63_19650	COG1994	Peptidase M50
EXW63_19655	COG1530	ribonuclease E activity
EXW63_19665	COG2868	ribosomal protein
EXW63_19675	COG3290	protein histidine kinase activity
EXW63_19680	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW63_19685	COG0745	RESPONSE REGULATOR receiver
EXW63_19690	COG5002	protein histidine kinase activity
EXW63_19695	COG1136	(ABC) transporter
EXW63_19700	COG0577	efflux transmembrane transporter activity
EXW63_19705	COG0577	efflux transmembrane transporter activity
EXW63_19710	COG0077	Prephenate dehydratase
EXW63_19715	COG2258	MOSC domain
EXW63_19720	COG1827	regulation of RNA biosynthetic process
EXW63_19725	COG1104	cysteine desulfurase activity
EXW63_19730	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW63_19735	COG0157	Belongs to the NadC ModD family
EXW63_19740	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW63_19765	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW63_19770	COG0632	four-way junction helicase activity
EXW63_19775	COG2255	four-way junction helicase activity
EXW63_19785	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW63_19790	COG0343	queuine tRNA-ribosyltransferase activity
EXW63_19795	COG1862	Preprotein translocase
EXW63_19805	COG2323	membrane
EXW63_19810	COG2244	polysaccharide biosynthetic process
EXW63_19820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW63_19820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW63_19825	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW63_19830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW63_19830	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW63_19835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW63_19840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW63_19845	COG1490	D-aminoacyl-tRNA deacylase activity
EXW63_19855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW63_19860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW63_19875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW63_19880	COG1959	2 iron, 2 sulfur cluster binding
EXW63_19885	COG1104	cysteine desulfurase activity
EXW63_19890	COG0482	sulfurtransferase activity
EXW63_19900	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW63_19920	COG0628	permease
EXW63_19930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW63_19935	COG4472	Bacterial protein of unknown function (DUF965)
EXW63_19940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW63_19950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW63_19955	COG4122	O-methyltransferase activity
EXW63_19960	COG0826	peptidase U32
EXW63_19965	COG0826	peptidase U32
EXW63_19970	COG0572	uridine kinase
EXW63_19975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW63_19980	COG0768	penicillin binding
EXW63_19995	COG2226	methyltransferase
EXW63_20000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW63_20005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW63_20010	COG0626	cystathionine gamma-synthase activity
EXW63_20015	COG1012	belongs to the aldehyde dehydrogenase family
EXW63_20015	COG1454	alcohol dehydrogenase
EXW63_20025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW63_20065	COG2259	Doxx family
EXW63_20070	COG2514	catechol 2,3-dioxygenase activity
EXW63_20075	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW63_20080	COG3186	Phenylalanine-4-hydroxylase
EXW63_20085	COG1404	Belongs to the peptidase S8 family
EXW63_20120	COG2267	carboxylic ester hydrolase activity
EXW63_20130	COG1785	Belongs to the alkaline phosphatase family
EXW63_20140	COG2357	RelA SpoT domain protein
EXW63_20145	COG1595	DNA-templated transcription, initiation
EXW63_20155	COG0688	phosphatidylethanolamine metabolic process
EXW63_20165	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW63_20170	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW63_20175	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW63_20180	COG1534	Rna-binding protein
EXW63_20185	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW63_20190	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW63_20195	COG0799	negative regulation of ribosome biogenesis
EXW63_20200	COG2226	methyltransferase
EXW63_20205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW63_20210	COG1555	photosystem II stabilization
EXW63_20210	COG1596	polysaccharide export
EXW63_20215	COG2131	deaminase
EXW63_20220	COG2333	competence protein COMEC
EXW63_20220	COG0658	competence protein
EXW63_20230	COG1466	dna polymerase III delta subunit
EXW63_20235	COG0268	Binds directly to 16S ribosomal RNA
EXW63_20240	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW63_20250	COG0481	GTPase activity
EXW63_20255	COG1733	regulation of RNA biosynthetic process
EXW63_20260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW63_20265	COG1420	regulation of RNA biosynthetic process
EXW63_20275	COG0443	Heat shock 70 kDa protein
EXW63_20280	COG0484	heat shock protein binding
EXW63_20290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW63_20295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW63_20300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW63_20305	COG1610	YqeY-like protein
EXW63_20320	COG1702	phosphate starvation-inducible protein PhoH
EXW63_20325	COG1480	7TM receptor with intracellular HD hydrolase
EXW63_20330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW63_20335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW63_20340	COG0295	cytidine deaminase activity
EXW63_20345	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW63_20355	COG1381	Involved in DNA repair and RecF pathway recombination
EXW63_20360	COG0517	IMP dehydrogenase activity
EXW63_20365	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW63_20375	COG0358	DNA primase activity
EXW63_20380	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW63_20390	COG2384	SAM-dependent methyltransferase
EXW63_20395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW63_20400	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW63_20415	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW63_20425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW63_20430	COG1121	(ABC) transporter
EXW63_20435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW63_20440	COG0735	belongs to the Fur family
EXW63_20445	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW63_20465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW63_20470	COG0477	Major facilitator Superfamily
EXW63_20475	COG0768	penicillin binding
EXW63_20480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW63_20485	COG0573	inorganic phosphate transmembrane transporter activity
EXW63_20490	COG0581	inorganic phosphate transmembrane transporter activity
EXW63_20505	COG0704	Plays a role in the regulation of phosphate uptake
EXW63_20510	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW63_20515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW63_20520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW63_20525	COG4483	Protein conserved in bacteria
EXW63_20530	COG1940	carbohydrate kinase activity
EXW63_20540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW63_20555	COG0626	cystathionine gamma-synthase activity
EXW63_20560	COG0626	cystathionine gamma-synthase activity
EXW63_20565	COG0646	methionine synthase
EXW63_20565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW63_20570	COG1410	methionine synthase
EXW63_20570	COG0646	methionine synthase
EXW63_20625	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW63_20630	COG1459	type II secretion system
EXW63_20640	COG4970	Tfp pilus assembly protein FimT
EXW63_20665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW63_20695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW63_20700	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW63_20705	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW63_20710	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW63_20725	COG1725	Transcriptional regulator
EXW63_20760	COG2076	Multidrug Resistance protein
EXW63_20765	COG2076	Multidrug Resistance protein
EXW63_20775	COG1609	Transcriptional regulator
EXW63_20785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW63_20815	COG1321	iron dependent repressor
EXW63_20820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW63_20830	COG3872	metal-dependent enzyme
EXW63_20840	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW63_20845	COG0006	proline dipeptidase activity
EXW63_20850	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW63_20870	COG3854	ATPases associated with a variety of cellular activities
EXW63_20915	COG0511	ligase activity, forming carbon-carbon bonds
EXW63_20920	COG0439	Biotin carboxylase
EXW63_20925	COG1302	Protein conserved in bacteria
EXW63_20930	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW63_20935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW63_20940	COG1570	exodeoxyribonuclease VII activity
EXW63_20945	COG1722	exodeoxyribonuclease VII activity
EXW63_20950	COG0142	geranyltranstransferase activity
EXW63_20955	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW63_20960	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW63_20965	COG1438	arginine binding
EXW63_20970	COG0497	DNA recombination
EXW63_20975	COG0750	zinc metalloprotease
EXW63_20985	COG0745	RESPONSE REGULATOR receiver
EXW63_20995	COG3093	addiction module antidote protein HigA
EXW63_21000	COG0584	glycerophosphoryl diester phosphodiesterase
EXW63_21010	COG3290	protein histidine kinase activity
EXW63_21010	COG3829	transcription factor binding
EXW63_21020	COG0280	phosphate acetyltransferase
EXW63_21030	COG3426	butyrate kinase activity
EXW63_21035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW63_21040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW63_21045	COG0022	dehydrogenase e1 component
EXW63_21050	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW63_21060	COG0772	Belongs to the SEDS family
EXW63_21065	COG2323	membrane
EXW63_21080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW63_21085	COG0765	amino acid transport
EXW63_21090	COG1126	abc transporter atp-binding protein
EXW63_21095	COG4129	membrane
EXW63_21100	COG1376	ErfK ybiS ycfS ynhG family protein
EXW63_21110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW63_21115	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW63_21140	COG1131	(ABC) transporter
EXW63_21175	COG1234	tRNA 3'-trailer cleavage
EXW63_21185	COG1760	l-serine dehydratase
EXW63_21190	COG1760	l-serine dehydratase
EXW63_21195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW63_21200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW63_21205	COG0300	oxidoreductase activity
EXW63_21220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW63_21230	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW63_21255	COG1522	sequence-specific DNA binding
EXW63_21265	COG0737	Belongs to the 5'-nucleotidase family
EXW63_21270	COG1757	Na H antiporter
EXW63_21285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW63_21295	COG0156	8-amino-7-oxononanoate synthase activity
EXW63_21300	COG2226	methyltransferase
EXW63_21300	COG1073	alpha beta
EXW63_21305	COG4106	trans-aconitate 2-methyltransferase activity
EXW63_21310	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW63_21325	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW63_21325	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW63_21330	COG0307	riboflavin synthase, alpha
EXW63_21335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW63_21335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW63_21350	COG1073	alpha beta
EXW63_21355	COG0456	acetyltransferase
EXW63_21360	COG1609	Transcriptional regulator
EXW63_21365	COG2056	Na+-H+ antiporter family
EXW63_21370	COG0596	Alpha beta hydrolase
EXW63_21380	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW63_21385	COG4085	toxin activity
EXW63_21385	COG1525	nuclease
EXW63_21385	COG0737	Belongs to the 5'-nucleotidase family
EXW63_21395	COG0456	acetyltransferase
EXW63_21395	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW63_21400	COG0656	L-ascorbic acid biosynthetic process
EXW63_21405	COG0667	Aldo Keto reductase
EXW63_21425	COG1300	Membrane
EXW63_21430	COG0735	belongs to the Fur family
EXW63_21440	COG4974	Belongs to the 'phage' integrase family
EXW63_21450	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW63_21465	COG0598	Magnesium transport protein CorA
EXW63_21480	COG1846	Transcriptional regulator
EXW63_21500	COG1131	(ABC) transporter
EXW63_21505	COG1725	Transcriptional regulator
EXW63_21510	COG1686	Belongs to the peptidase S11 family
EXW63_21530	COG0733	neurotransmitter:sodium symporter activity
EXW63_21555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW63_21570	COG0697	spore germination
EXW63_21575	COG0561	phosphatase activity
EXW63_21580	COG4086	secreted protein
EXW63_21585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW63_21595	COG1547	Domain of unknown function (DUF309)
EXW63_21605	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW63_21615	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW63_21625	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW63_21630	COG0363	glucosamine-6-phosphate deaminase activity
EXW63_21635	COG2188	Transcriptional regulator
EXW63_21645	COG3711	transcriptional antiterminator
EXW63_21650	COG1263	PTS System
EXW63_21650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW63_21650	COG2190	(PTS) system
EXW63_21675	COG0778	Nitroreductase
EXW63_21680	COG2199	diguanylate cyclase activity
EXW63_21690	COG2084	Dehydrogenase
EXW63_21705	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW63_21710	COG0235	Class ii aldolase
EXW63_21715	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW63_21720	COG1850	ribulose-bisphosphate carboxylase activity
EXW63_21725	COG0436	Aminotransferase
EXW63_21730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW63_21735	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW63_21740	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW63_21750	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_21755	COG1695	Transcriptional regulator
EXW63_21790	COG0183	Belongs to the thiolase family
EXW63_21835	COG3842	ATPase activity
EXW63_21840	COG0366	Alpha amylase catalytic
EXW63_21850	COG2182	Extracellular solute-binding protein
EXW63_21855	COG1175	transmembrane transport
EXW63_21860	COG3833	ABC-type maltose transport systems, permease component
EXW63_21865	COG1609	Transcriptional regulator
EXW63_21870	COG0436	Aminotransferase
EXW63_21880	COG2205	protein histidine kinase activity
EXW63_21890	COG3209	COG3209 Rhs family protein
EXW63_21900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW63_21910	COG2814	Major facilitator Superfamily
EXW63_21955	COG1408	metallophosphoesterase
EXW63_21960	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_21965	COG2200	EAL domain
EXW63_21980	COG4703	Protein of unknown function (DUF1797)
EXW63_21990	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW63_22000	COG0517	IMP dehydrogenase activity
EXW63_22005	COG0583	DNA-binding transcription factor activity
EXW63_22010	COG2171	N-acyltransferase activity
EXW63_22015	COG1473	amidohydrolase
EXW63_22025	COG0569	domain protein
EXW63_22030	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW63_22035	COG5503	Protein of unknown function (DUF1447)
EXW63_22045	COG0561	phosphatase activity
EXW63_22060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW63_22065	COG0022	dehydrogenase e1 component
EXW63_22070	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW63_22115	COG1982	Orn Lys Arg decarboxylase major
EXW63_22125	COG4476	Belongs to the UPF0223 family
EXW63_22130	COG4493	Belongs to the UPF0637 family
EXW63_22140	COG0483	inositol monophosphate 1-phosphatase activity
EXW63_22150	COG1217	gtp-binding protein TYPA
EXW63_22165	COG4896	Protein conserved in bacteria
EXW63_22175	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW63_22180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW63_22185	COG4838	Belongs to the UPF0358 family
EXW63_22190	COG0772	Belongs to the SEDS family
EXW63_22200	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW63_22205	COG1612	heme a metabolic process
EXW63_22210	COG0109	protoheme IX farnesyltransferase activity
EXW63_22235	COG3336	cytochrome c oxidase
EXW63_22245	COG2340	Cysteine-rich secretory protein family
EXW63_22260	COG0406	alpha-ribazole phosphatase activity
EXW63_22265	COG3679	Belongs to the UPF0342 family
EXW63_22270	COG4471	UPF0298 protein
EXW63_22280	COG0742	ribosomal rna small subunit methyltransferase
EXW63_22285	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EXW63_22290	COG3314	Sporulation integral membrane protein YlbJ
EXW63_22295	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW63_22300	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW63_22305	COG1323	Belongs to the UPF0348 family
EXW63_22310	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW63_22315	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW63_22325	COG0454	-acetyltransferase
EXW63_22330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW63_22335	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW63_22340	COG0275	rRNA processing
EXW63_22350	COG0768	penicillin binding
EXW63_22355	COG0768	penicillin binding
EXW63_22360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW63_22365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW63_22370	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW63_22375	COG0772	Belongs to the SEDS family
EXW63_22390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW63_22395	COG0849	cell division
EXW63_22400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW63_22410	COG1191	sigma factor activity
EXW63_22415	COG1191	sigma factor activity
EXW63_22420	COG1873	PFAM PRC-barrel domain
EXW63_22430	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW63_22435	COG1799	cell septum assembly
EXW63_22440	COG0762	integral membrane protein
EXW63_22445	COG2302	S4 RNA-binding domain
EXW63_22450	COG3599	regulation of cell shape
EXW63_22455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW63_22465	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW63_22470	COG0564	pseudouridine synthase activity
EXW63_22475	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW63_22485	COG0540	Belongs to the ATCase OTCase family
EXW63_22490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW63_22500	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW63_22505	COG0543	2 iron, 2 sulfur cluster binding
EXW63_22510	COG0167	dihydroorotate dehydrogenase activity
EXW63_22570	COG0006	proline dipeptidase activity
EXW63_22585	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW63_22590	COG1561	YicC-like family, N-terminal region
EXW63_22605	COG1758	RNA polymerase activity
EXW63_22610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW63_22615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW63_22620	COG0242	peptide deformylase activity
EXW63_22625	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW63_22630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW63_22630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW63_22635	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW63_22640	COG0631	protein serine/threonine phosphatase activity
EXW63_22645	COG2815	serine threonine protein kinase
EXW63_22645	COG0515	serine threonine protein kinase
EXW63_22655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW63_22660	COG1564	THIamine pyrophosphokinase
EXW63_22675	COG1302	Protein conserved in bacteria
EXW63_22680	COG1461	Dihydroxyacetone kinase
EXW63_22685	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW63_22690	COG2050	protein possibly involved in aromatic compounds catabolism
EXW63_22690	COG1349	DNA-binding transcription factor activity
EXW63_22695	COG0416	fatty acid biosynthetic process
EXW63_22700	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW63_22705	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_22710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW63_22715	COG0571	ribonuclease III activity
EXW63_22720	COG1196	nuclear chromosome segregation
EXW63_22725	COG0552	protein localization to endoplasmic reticulum
EXW63_22730	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EXW63_22735	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW63_22745	COG1837	Belongs to the UPF0109 family
EXW63_22750	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW63_22755	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW63_22760	COG0335	large ribosomal subunit rRNA binding
EXW63_22775	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW63_22780	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW63_22785	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW63_22790	COG0758	DNA mediated transformation
EXW63_22795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW63_22800	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW63_22805	COG4974	Belongs to the 'phage' integrase family
EXW63_22810	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW63_22815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW63_22820	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW63_22825	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW63_22830	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW63_22835	COG0528	UMP kinase activity
EXW63_22840	COG0233	cytoplasmic translational termination
EXW63_22850	COG4589	Belongs to the CDS family
EXW63_22860	COG0750	zinc metalloprotease
EXW63_22865	COG0442	prolyl-tRNA aminoacylation
EXW63_22875	COG0779	Required for maturation of 30S ribosomal subunits
EXW63_22880	COG0195	Participates in both transcription termination and antitermination
EXW63_22885	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW63_22890	COG1358	cellular component organization or biogenesis
EXW63_22895	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW63_22900	COG1550	Protein conserved in bacteria
EXW63_22905	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW63_22915	COG0196	riboflavin kinase activity
EXW63_22925	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW63_22930	COG0726	polysaccharide deacetylase
EXW63_22935	COG0612	Peptidase, M16
EXW63_22940	COG1873	PFAM PRC-barrel domain
EXW63_22945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW63_22950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW63_22955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW63_22960	COG0527	aspartate kinase activity
EXW63_22970	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW63_22975	COG0740	serine-type endopeptidase activity
EXW63_22985	COG1674	ftsk spoiiie
EXW63_22990	COG2188	Transcriptional regulator
EXW63_22995	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW63_23000	COG3845	ABC transporter
EXW63_23005	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW63_23010	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW63_23015	COG0612	Peptidase, M16
EXW63_23020	COG0612	Peptidase, M16
EXW63_23025	COG0300	oxidoreductase activity
EXW63_23040	COG1426	Protein conserved in bacteria
EXW63_23045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW63_23050	COG1058	Belongs to the CinA family
EXW63_23050	COG1546	Belongs to the CinA family
EXW63_23055	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW63_23060	COG1418	mRNA catabolic process
EXW63_23065	COG1692	metallophosphoesterase
EXW63_23070	COG2359	stage V sporulation protein S
EXW63_23080	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW63_23080	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW63_23085	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW63_23090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW63_23095	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW63_23105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW63_23110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW63_23120	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW63_23135	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW63_23140	COG1368	sulfuric ester hydrolase activity
EXW63_23155	COG3773	Cell wall hydrolase
EXW63_23165	COG0840	transmembrane signaling receptor activity
EXW63_23170	COG2723	6-phospho-beta-galactosidase activity
EXW63_23175	COG2188	Transcriptional regulator
EXW63_23185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW63_23190	COG0596	Alpha beta hydrolase
EXW63_23190	COG2945	thiolester hydrolase activity
EXW63_23195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW63_23205	COG1346	cytolysis
EXW63_23245	COG3300	MHYT domain
EXW63_23245	COG5001	Diguanylate cyclase
EXW63_23250	COG0346	lactoylglutathione lyase activity
EXW63_23255	COG2267	carboxylic ester hydrolase activity
EXW63_23270	COG2364	Membrane
EXW63_23275	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW63_23280	COG2706	6-phosphogluconolactonase activity
EXW63_23290	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW63_23295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW63_23300	COG2169	Transcriptional regulator
EXW63_23305	COG0708	Exodeoxyribonuclease III
EXW63_23310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW63_23315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW63_23320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW63_23325	COG1120	ATPase activity
EXW63_23330	COG2819	hydrolase of the alpha beta superfamily
EXW63_23335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW63_23340	COG4566	intracellular signal transduction
EXW63_23370	COG1937	Protein conserved in bacteria
EXW63_23375	COG2608	mercury ion transmembrane transporter activity
EXW63_23380	COG2217	Heavy metal translocating P-type atpase
EXW63_23395	COG2116	formate transmembrane transporter activity
EXW63_23400	COG1408	metallophosphoesterase
EXW63_23405	COG1473	amidohydrolase
EXW63_23420	COG1113	amino acid transport
EXW63_23430	COG2322	membrane
EXW63_23435	COG1979	alcohol dehydrogenase
EXW63_23440	COG1349	DNA-binding transcription factor activity
EXW63_23445	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW63_23450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW63_23450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW63_23450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW63_23455	COG1388	LysM domain
EXW63_23455	COG3584	3D domain protein
EXW63_23465	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW63_23485	COG0464	growth
EXW63_23490	COG2860	membrane
EXW63_23495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW63_23500	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW63_23505	COG0789	Transcriptional regulator
EXW63_23510	COG0174	glutamine synthetase
EXW63_23515	COG3944	biosynthesis protein
EXW63_23520	COG0489	protein tyrosine kinase activity
EXW63_23525	COG1086	Polysaccharide biosynthesis protein
EXW63_23530	COG0438	transferase activity, transferring glycosyl groups
EXW63_23535	COG0438	transferase activity, transferring glycosyl groups
EXW63_23540	COG0463	Glycosyl transferase, family 2
EXW63_23540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW63_23560	COG1216	Glycosyl transferase, family 2
EXW63_23590	COG3420	alginic acid biosynthetic process
EXW63_23590	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW63_23595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW63_23605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW63_23640	COG1132	(ABC) transporter
EXW63_23645	COG1695	Transcriptional regulator
EXW63_23660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW63_23665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW63_23675	COG0737	Belongs to the 5'-nucleotidase family
EXW63_23680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW63_23690	COG3639	organic phosphonate transmembrane transporter activity
EXW63_23710	COG3763	UPF0154 protein
EXW63_23785	COG4932	domain protein
EXW63_23785	COG4886	Leucine-rich repeat (LRR) protein
EXW63_23805	COG1132	(ABC) transporter
EXW63_23810	COG1132	(ABC) transporter
EXW63_23830	COG3409	Peptidoglycan-binding domain 1 protein
EXW63_23830	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW63_23840	COG0730	response to heat
EXW63_23855	COG1346	cytolysis
EXW63_23865	COG0583	DNA-binding transcription factor activity
EXW63_23875	COG1131	(ABC) transporter
EXW63_23880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW63_23885	COG1473	amidohydrolase
EXW63_23900	COG0785	Cytochrome C biogenesis protein
EXW63_23905	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW63_23935	COG2226	methyltransferase
EXW63_23945	COG2986	histidine ammonia-lyase
EXW63_23950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW63_23960	COG0010	Belongs to the arginase family
EXW63_23965	COG1329	Transcriptional regulator
EXW63_23970	COG1902	pentaerythritol trinitrate reductase activity
EXW63_23975	COG0069	glutamate synthase activity
EXW63_23985	COG0346	lactoylglutathione lyase activity
EXW63_23990	COG0400	carboxylic ester hydrolase activity
EXW63_24000	COG5002	protein histidine kinase activity
EXW63_24015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW63_24055	COG1396	sequence-specific DNA binding
EXW63_24060	COG0318	PFAM AMP-dependent synthetase and ligase
EXW63_24065	COG1268	BioY protein
EXW63_24070	COG0318	PFAM AMP-dependent synthetase and ligase
EXW63_24075	COG0183	Belongs to the thiolase family
EXW63_24090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW63_24100	COG2211	Major facilitator Superfamily
EXW63_24130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW63_24135	COG1266	CAAX protease self-immunity
EXW63_24150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW63_24175	COG0824	Thioesterase
EXW63_24180	COG4841	protein insertion into membrane
EXW63_24190	COG1328	CTP reductase activity
EXW63_24190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW63_24200	COG0745	RESPONSE REGULATOR receiver
EXW63_24205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW63_24210	COG1832	CoA-binding protein
EXW63_24215	COG0187	DNA topoisomerase II activity
EXW63_24220	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW63_24225	COG0673	inositol 2-dehydrogenase activity
EXW63_24245	COG1131	(ABC) transporter
EXW63_24255	COG4166	transmembrane transport
EXW63_24260	COG4166	transmembrane transport
EXW63_24265	COG4166	transmembrane transport
EXW63_24270	COG2226	methyltransferase
EXW63_24300	COG0531	amino acid
EXW63_24305	COG3326	Membrane
EXW63_24310	COG2962	Rard protein
EXW63_24315	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW63_24320	COG1657	PFAM Prenyltransferase squalene oxidase
EXW63_24330	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_24335	COG1012	belongs to the aldehyde dehydrogenase family
EXW63_24345	COG4145	pantothenate transmembrane transporter activity
EXW63_24360	COG0165	Argininosuccinate lyase
EXW63_24370	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_24390	COG0494	nUDIX hydrolase
EXW63_24400	COG0716	FMN binding
EXW63_24410	COG1278	Cold shock
EXW63_24435	COG2720	vancomycin resistance protein
EXW63_24440	COG0765	amino acid transport
EXW63_24445	COG1126	abc transporter atp-binding protein
EXW63_24450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW63_24455	COG2514	catechol 2,3-dioxygenase activity
EXW63_24470	COG1285	pathogenesis
EXW63_24490	COG0277	FAD linked oxidase domain protein
EXW63_24500	COG2808	Putative FMN-binding domain
EXW63_24505	COG0457	Tetratricopeptide repeat
EXW63_24515	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW63_24520	COG0604	alcohol dehydrogenase
EXW63_24525	COG0640	Transcriptional regulator
EXW63_24530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW63_24565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW63_24580	COG3781	membrane
EXW63_24600	COG2957	Belongs to the agmatine deiminase family
EXW63_24605	COG1164	Oligoendopeptidase f
EXW63_24610	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW63_24630	COG1193	negative regulation of DNA recombination
EXW63_24655	COG0583	DNA-binding transcription factor activity
EXW63_24660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW63_24685	COG3739	integral membrane protein
EXW63_24690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW63_24695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW63_24700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW63_24720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW63_24725	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW63_24755	COG2814	Major facilitator Superfamily
EXW63_24765	COG1113	amino acid transport
EXW63_24770	COG0604	alcohol dehydrogenase
EXW63_24775	COG1695	Transcriptional regulator
EXW63_24820	COG2072	flavoprotein involved in K transport
EXW63_24865	COG1151	hydroxylamine reductase activity
EXW63_24890	COG0814	amino acid
EXW63_24920	COG1280	lysine exporter protein (LysE YggA)
EXW63_24925	COG3226	Transcriptional regulator
EXW63_24935	COG1309	transcriptional regulator
EXW63_24940	COG2814	Major facilitator Superfamily
EXW63_24950	COG0657	acetylesterase activity
EXW63_24970	COG0745	RESPONSE REGULATOR receiver
EXW63_24975	COG5002	protein histidine kinase activity
EXW63_24995	COG0741	lytic transglycosylase activity
EXW63_25020	COG1876	peptidase activity
EXW63_25050	COG1191	sigma factor activity
EXW63_25065	COG1733	regulation of RNA biosynthetic process
EXW63_25070	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW63_25075	COG0318	PFAM AMP-dependent synthetase and ligase
EXW63_25085	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_25110	COG0494	nUDIX hydrolase
EXW63_25125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW63_25135	COG1393	Belongs to the ArsC family
EXW63_25155	COG0814	amino acid
EXW63_25170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW63_25175	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW63_25185	COG1070	Carbohydrate kinase
EXW63_25190	COG2706	6-phosphogluconolactonase activity
EXW63_25195	COG3813	Protein conserved in bacteria
EXW63_25200	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW63_25205	COG0697	spore germination
EXW63_25210	COG0789	Transcriptional regulator
EXW63_25215	COG1253	flavin adenine dinucleotide binding
EXW63_25225	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW63_25260	COG2261	transglycosylase associated protein
EXW63_25265	COG0628	permease
EXW63_25280	COG0110	maltose O-acetyltransferase activity
EXW63_25285	COG0738	Major facilitator superfamily
EXW63_25290	COG1940	carbohydrate kinase activity
EXW63_25295	COG0346	lactoylglutathione lyase activity
EXW63_25320	COG2365	Tyrosine phosphatase family
EXW63_25325	COG1011	Hydrolase
EXW63_25340	COG0494	nUDIX hydrolase
EXW63_25360	COG1131	(ABC) transporter
EXW63_25370	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_25390	COG1733	regulation of RNA biosynthetic process
EXW63_25395	COG0778	Nitroreductase
EXW63_25400	COG1785	Belongs to the alkaline phosphatase family
EXW63_25420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW63_25445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW63_25450	COG2356	endonuclease I
EXW63_25455	COG1288	antiporter activity
EXW63_25460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW63_25480	COG1122	ATPase activity
EXW63_25525	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW63_25535	COG2031	fatty acid transporter
EXW63_25550	COG4187	Peptidase family M20/M25/M40
EXW63_25605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW63_25655	COG0739	heme binding
EXW63_25685	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW63_25715	COG0494	nUDIX hydrolase
EXW63_25770	COG2003	Belongs to the UPF0758 family
EXW63_25775	COG1609	Transcriptional regulator
EXW63_25780	COG2814	Major facilitator Superfamily
EXW63_25785	COG0673	inositol 2-dehydrogenase activity
EXW63_25810	COG0191	fructose-bisphosphate aldolase activity
EXW63_25815	COG3718	enzyme involved in inositol metabolism
EXW63_25860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW63_25865	COG1288	antiporter activity
EXW63_25880	COG1476	TRANSCRIPTIONal
EXW63_25915	COG0789	Transcriptional regulator
EXW63_25925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW63_25935	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EXW63_25950	COG2814	Major facilitator Superfamily
EXW63_25955	COG1846	Transcriptional regulator
EXW63_25970	COG0477	Major facilitator Superfamily
EXW63_25985	COG2843	Capsule synthesis protein
EXW63_25990	COG1876	peptidase activity
EXW63_26010	COG2814	Major facilitator Superfamily
EXW63_26075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW63_26095	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW63_26115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW63_26130	COG3850	Histidine kinase
EXW63_26130	COG5002	protein histidine kinase activity
EXW63_26150	COG0577	efflux transmembrane transporter activity
EXW63_26155	COG1136	(ABC) transporter
EXW63_26175	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW63_26195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW63_26205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW63_26245	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW63_26275	COG5002	protein histidine kinase activity
EXW63_26275	COG3850	Histidine kinase
EXW63_26280	COG0745	RESPONSE REGULATOR receiver
EXW63_26305	COG2814	Major facilitator Superfamily
EXW63_26315	COG2226	methyltransferase
EXW63_26335	COG0346	lactoylglutathione lyase activity
EXW63_26350	COG1522	sequence-specific DNA binding
EXW63_26355	COG1028	Short-chain dehydrogenase reductase Sdr
EXW63_26410	COG0640	Transcriptional regulator
EXW63_26415	COG0346	lactoylglutathione lyase activity
EXW63_26420	COG0798	PFAM Bile acid sodium symporter
EXW63_26445	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW63_26450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW63_26455	COG1999	signal sequence binding
EXW63_26470	COG1121	(ABC) transporter
EXW63_26475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW63_26480	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW63_26500	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW63_26545	COG1073	alpha beta
EXW63_26580	COG1136	(ABC) transporter
EXW63_26605	COG3848	Pyruvate phosphate dikinase
EXW63_26605	COG0574	Belongs to the PEP-utilizing enzyme family
EXW63_26620	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW63_26640	COG0640	Transcriptional regulator
EXW63_26665	COG1960	acyl-CoA dehydrogenase activity
EXW63_26685	COG1414	Transcriptional regulator
EXW63_26690	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW63_26695	COG1984	allophanate hydrolase subunit 2
EXW63_26700	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW63_26715	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW63_26720	COG3104	oligopeptide transport
EXW63_26730	COG0768	penicillin binding
EXW63_26765	COG4335	DNA alkylation repair
EXW63_26775	COG0833	amino acid
EXW63_26785	COG0730	response to heat
EXW63_26810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW63_26810	COG0456	acetyltransferase
EXW63_26830	COG1671	Belongs to the UPF0178 family
EXW63_26835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW63_26840	COG0697	spore germination
EXW63_26855	COG0456	acetyltransferase
EXW63_26860	COG2207	Transcriptional regulator
EXW63_26890	COG1725	Transcriptional regulator
EXW63_26910	COG0494	nUDIX hydrolase
EXW63_26930	COG1846	Transcriptional regulator
EXW63_26935	COG0778	Nitroreductase
EXW63_26955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW63_26965	COG0753	catalase activity
EXW63_26970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW63_26990	COG0714	Associated with various cellular activities
EXW63_27025	COG0346	lactoylglutathione lyase activity
EXW63_27030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW63_27045	COG3279	Response regulator of the LytR AlgR family
EXW63_27055	COG4377	Putative membrane peptidase family (DUF2324)
EXW63_27070	COG3655	Transcriptional regulator
EXW63_27090	COG3239	Fatty acid desaturase
EXW63_27095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW63_27100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW63_27105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW63_27110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW63_27115	COG2207	Transcriptional regulator
EXW63_27120	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW63_27140	COG2329	Antibiotic biosynthesis monooxygenase
EXW63_27145	COG0346	lactoylglutathione lyase activity
EXW63_27160	COG2226	methyltransferase
EXW63_27165	COG1830	Aldolase
EXW63_27195	COG0579	oxidoreductase
EXW63_27230	COG0346	lactoylglutathione lyase activity
EXW63_27255	COG5002	protein histidine kinase activity
EXW63_27290	COG0778	Nitroreductase
EXW63_27315	COG0384	phenazine biosynthesis protein PhzF
EXW63_27320	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EXW63_27340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW63_27355	COG1674	ftsk spoiiie
EXW63_27480	COG0367	asparagine synthase
EXW63_27655	COG1396	sequence-specific DNA binding
EXW63_27720	COG0463	Glycosyl transferase, family 2
EXW63_27725	COG0463	Glycosyl transferase, family 2
EXW63_27730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW63_27735	COG1086	Polysaccharide biosynthesis protein
EXW63_27740	COG1088	dTDP-glucose 4,6-dehydratase activity
EXW63_27745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW63_27750	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW63_27765	COG2089	acid synthase
EXW63_27770	COG4641	Protein conserved in bacteria
EXW63_27810	COG2720	vancomycin resistance protein
EXW63_27845	COG2755	lipolytic protein G-D-S-L family
EXW63_27845	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW63_27865	COG0756	dUTP diphosphatase activity
EXW63_27915	COG2002	toxin-antitoxin pair type II binding
EXW63_27925	COG1923	regulation of RNA biosynthetic process
EXW63_27955	COG2814	Major facilitator Superfamily
EXW63_27980	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW63_27990	COG2002	toxin-antitoxin pair type II binding
EXW63_28025	COG0582	viral genome integration into host DNA
EXW63_28060	COG1696	Membrane protein involved in D-alanine export
EXW63_28070	COG2814	Major facilitator Superfamily
EXW63_28090	COG3344	reverse transcriptase
EXW63_28130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW63_28155	COG0791	NLP P60 protein
EXW63_28155	COG1388	LysM domain
EXW63_28155	COG3103	Sh3 type 3 domain protein
EXW63_28175	COG4974	Belongs to the 'phage' integrase family
EXW63_28195	COG3344	reverse transcriptase
EXW63_28220	COG0083	homoserine kinase activity
EXW63_28260	COG0840	transmembrane signaling receptor activity
EXW63_28275	COG2267	carboxylic ester hydrolase activity
EXW63_28285	COG1285	pathogenesis
EXW63_28290	COG0833	amino acid
EXW63_28320	COG0745	RESPONSE REGULATOR receiver
EXW63_28345	COG3344	reverse transcriptase
EXW63_28370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW63_28380	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EXW63_28385	COG5002	protein histidine kinase activity
EXW63_28390	COG0745	RESPONSE REGULATOR receiver
EXW63_28395	COG4990	cell redox homeostasis
EXW63_28405	COG0768	penicillin binding
EXW63_28410	COG0583	DNA-binding transcription factor activity
EXW63_28425	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW63_28445	COG2333	competence protein COMEC
EXW63_28445	COG0658	competence protein
EXW63_28500	COG2423	ornithine cyclodeaminase activity
EXW63_28510	COG2175	clavaminate synthase activity
EXW63_28515	COG0137	argininosuccinate synthase activity
EXW63_28530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW63_28535	COG0251	oxidation-reduction process
EXW63_28545	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW63_28550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW63_28555	COG1960	acyl-CoA dehydrogenase activity
EXW63_28580	COG0556	nucleotide-excision repair
EXW63_28585	COG0039	L-malate dehydrogenase activity
EXW63_28605	COG0436	Aminotransferase
EXW63_28645	COG0492	ferredoxin-NADP+ reductase activity
EXW63_28660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW63_28660	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EXW63_28670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW63_28675	COG1960	acyl-CoA dehydrogenase activity
EXW63_28690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW63_28700	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EXW63_28730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW63_28740	COG0438	transferase activity, transferring glycosyl groups
EXW63_28745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW63_28750	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW63_28765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW63_28775	COG1131	(ABC) transporter
EXW63_28790	COG2378	regulation of single-species biofilm formation
EXW63_28830	COG2002	toxin-antitoxin pair type II binding
EXW63_28900	COG2814	Major facilitator Superfamily
EXW63_28905	COG0583	DNA-binding transcription factor activity
EXW63_28980	COG2357	RelA SpoT domain protein
EXW63_28985	COG2814	Major facilitator Superfamily
EXW63_28995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW63_29105	COG3344	reverse transcriptase
EXW63_29155	COG1725	Transcriptional regulator
EXW63_29160	COG1131	(ABC) transporter
EXW63_29200	COG1329	Transcriptional regulator
EXW63_29215	COG1923	regulation of RNA biosynthetic process
EXW63_29235	COG0582	viral genome integration into host DNA
EXW63_29260	COG1695	Transcriptional regulator
EXW63_29340	COG0791	NLP P60 protein
EXW63_29340	COG3883	PFAM NLP P60 protein
EXW63_29420	COG1396	sequence-specific DNA binding
EXW63_29455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW63_29460	COG4974	Belongs to the 'phage' integrase family
EXW63_29465	COG0024	Methionine aminopeptidase