locus-tag	class	description
EXW27_00005	COG1802	Transcriptional regulator
EXW27_00005	COG4626	Terminase
EXW27_00015	COG0740	serine-type endopeptidase activity
EXW27_00140	COG1846	Transcriptional regulator
EXW27_00145	COG0778	Nitroreductase
EXW27_00165	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW27_00175	COG0753	catalase activity
EXW27_00180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW27_00200	COG0714	Associated with various cellular activities
EXW27_00235	COG0346	lactoylglutathione lyase activity
EXW27_00240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW27_00255	COG3279	Response regulator of the LytR AlgR family
EXW27_00265	COG4377	Putative membrane peptidase family (DUF2324)
EXW27_00280	COG3655	Transcriptional regulator
EXW27_00290	COG1349	DNA-binding transcription factor activity
EXW27_00295	COG1175	transmembrane transport
EXW27_00320	COG3842	ATPase activity
EXW27_00335	COG3239	Fatty acid desaturase
EXW27_00340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW27_00345	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW27_00350	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW27_00355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW27_00375	COG2329	Antibiotic biosynthesis monooxygenase
EXW27_00395	COG2226	methyltransferase
EXW27_00415	COG2390	Transcriptional regulator
EXW27_00420	COG1129	ABC transporter
EXW27_00435	COG1879	ABC-type sugar transport system periplasmic component
EXW27_00440	COG0579	oxidoreductase
EXW27_00470	COG0431	NADPH-dependent FMN reductase
EXW27_00480	COG0346	lactoylglutathione lyase activity
EXW27_00530	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW27_00530	COG1605	Chorismate mutase
EXW27_00545	COG0287	Prephenate dehydrogenase
EXW27_00570	COG1309	transcriptional regulator
EXW27_00580	COG2409	Drug exporters of the RND superfamily
EXW27_00580	COG1033	growth of symbiont in host cell
EXW27_00585	COG0488	(ABC) transporter
EXW27_00600	COG1368	sulfuric ester hydrolase activity
EXW27_00605	COG2814	Major facilitator Superfamily
EXW27_00655	COG0697	spore germination
EXW27_00665	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW27_00710	COG0628	permease
EXW27_00755	COG2188	Transcriptional regulator
EXW27_00760	COG1131	(ABC) transporter
EXW27_00785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW27_00790	COG0436	Aminotransferase
EXW27_00825	COG2226	methyltransferase
EXW27_00840	COG2261	transglycosylase associated protein
EXW27_00860	COG2814	Major facilitator Superfamily
EXW27_00860	COG0477	Major facilitator Superfamily
EXW27_00865	COG4533	DNA binding
EXW27_00870	COG0789	Transcriptional regulator
EXW27_00875	COG1664	Polymer-forming cytoskeletal
EXW27_00885	COG2814	Major facilitator Superfamily
EXW27_00900	COG1335	isochorismatase
EXW27_00930	COG1307	EDD domain protein, DegV family
EXW27_00945	COG1522	sequence-specific DNA binding
EXW27_00950	COG0531	amino acid
EXW27_00955	COG1164	Oligoendopeptidase f
EXW27_00985	COG0745	RESPONSE REGULATOR receiver
EXW27_00995	COG2936	dipeptidyl-peptidase activity
EXW27_01035	COG0667	Aldo Keto reductase
EXW27_01055	COG4948	Mandelate Racemase Muconate Lactonizing
EXW27_01065	COG4166	transmembrane transport
EXW27_01070	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW27_01085	COG0586	Pfam SNARE associated Golgi protein
EXW27_01125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW27_01130	COG3938	Belongs to the proline racemase family
EXW27_01140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW27_01145	COG1012	belongs to the aldehyde dehydrogenase family
EXW27_01150	COG1115	amino acid carrier protein
EXW27_01155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW27_01175	COG2318	DinB family
EXW27_01180	COG3397	chitin binding
EXW27_01185	COG1227	inorganic diphosphatase activity
EXW27_01195	COG4637	Psort location Cytoplasmic, score
EXW27_01215	COG0514	ATP-dependent DNA helicase (RecQ)
EXW27_01230	COG3973	AAA domain
EXW27_01285	COG2315	Protein conserved in bacteria
EXW27_01290	COG2226	methyltransferase
EXW27_01295	COG2205	protein histidine kinase activity
EXW27_01315	COG1819	glycosyl
EXW27_01325	COG3397	chitin binding
EXW27_01330	COG2153	protein acetylation
EXW27_01335	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW27_01360	COG4175	Glycine betaine
EXW27_01360	COG0517	IMP dehydrogenase activity
EXW27_01365	COG4176	ABC-type proline glycine betaine transport system permease component
EXW27_01395	COG0456	acetyltransferase
EXW27_01395	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW27_01400	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_01420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW27_01425	COG0022	dehydrogenase e1 component
EXW27_01430	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW27_01435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW27_01450	COG1959	2 iron, 2 sulfur cluster binding
EXW27_01470	COG1349	DNA-binding transcription factor activity
EXW27_01485	COG3284	Transcriptional regulator
EXW27_01500	COG1309	transcriptional regulator
EXW27_01505	COG3844	kynureninase activity
EXW27_01510	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW27_01515	COG3483	tryptophan 2,3-dioxygenase activity
EXW27_01545	COG2959	enzyme of heme biosynthesis
EXW27_01560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW27_01600	COG3386	PFAM SMP-30 Gluconolaconase
EXW27_01610	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW27_01615	COG3773	Cell wall hydrolase
EXW27_01630	COG0745	RESPONSE REGULATOR receiver
EXW27_01635	COG2205	protein histidine kinase activity
EXW27_01640	COG0583	DNA-binding transcription factor activity
EXW27_01645	COG0667	Aldo Keto reductase
EXW27_01650	COG0488	(ABC) transporter
EXW27_01660	COG1136	(ABC) transporter
EXW27_01665	COG0577	efflux transmembrane transporter activity
EXW27_01685	COG0460	homoserine dehydrogenase
EXW27_01690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW27_01700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW27_01745	COG2124	cytochrome p450
EXW27_01795	COG0561	phosphatase activity
EXW27_01800	COG5002	protein histidine kinase activity
EXW27_01805	COG0768	penicillin binding
EXW27_01815	COG1819	glycosyl
EXW27_01820	COG1794	racemase activity, acting on amino acids and derivatives
EXW27_01825	COG4720	Psort location CytoplasmicMembrane, score
EXW27_01830	COG1122	ATPase activity
EXW27_01845	COG2205	protein histidine kinase activity
EXW27_01855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW27_01865	COG0745	RESPONSE REGULATOR receiver
EXW27_01870	COG5002	protein histidine kinase activity
EXW27_01875	COG0604	alcohol dehydrogenase
EXW27_01880	COG0671	phosphoesterase, PA-phosphatase related
EXW27_01885	COG0768	penicillin binding
EXW27_01925	COG2814	Major facilitator Superfamily
EXW27_01940	COG0584	glycerophosphoryl diester phosphodiesterase
EXW27_01955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW27_01960	COG0697	spore germination
EXW27_01990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW27_01995	COG2223	nitrite transmembrane transporter activity
EXW27_02005	COG2816	NAD+ diphosphatase activity
EXW27_02010	COG0592	DNA-directed DNA polymerase activity
EXW27_02015	COG1051	belongs to the nudix hydrolase family
EXW27_02040	COG3878	Protein conserved in bacteria
EXW27_02065	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW27_02080	COG2318	DinB family
EXW27_02105	COG0322	excinuclease ABC activity
EXW27_02125	COG3961	Belongs to the TPP enzyme family
EXW27_02135	COG1132	(ABC) transporter
EXW27_02145	COG1183	phosphatidylcholine synthase activity
EXW27_02150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW27_02170	COG1011	Hydrolase
EXW27_02175	COG0745	RESPONSE REGULATOR receiver
EXW27_02180	COG5002	protein histidine kinase activity
EXW27_02210	COG1136	(ABC) transporter
EXW27_02215	COG0577	efflux transmembrane transporter activity
EXW27_02225	COG1073	alpha beta
EXW27_02235	COG0657	acetylesterase activity
EXW27_02240	COG0076	glutamate decarboxylase activity
EXW27_02255	COG1523	belongs to the glycosyl hydrolase 13 family
EXW27_02260	COG3227	Zinc metalloprotease (Elastase)
EXW27_02265	COG0737	Belongs to the 5'-nucleotidase family
EXW27_02275	COG0201	protein transport
EXW27_02295	COG0697	spore germination
EXW27_02300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW27_02315	COG2323	membrane
EXW27_02350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW27_02355	COG0697	spore germination
EXW27_02385	COG1309	transcriptional regulator
EXW27_02410	COG1733	regulation of RNA biosynthetic process
EXW27_02415	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_02440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW27_02465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW27_02490	COG1686	Belongs to the peptidase S11 family
EXW27_02495	COG2318	DinB family
EXW27_02540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW27_02545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW27_02550	COG1024	Enoyl-CoA hydratase
EXW27_02555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW27_02560	COG0511	ligase activity, forming carbon-carbon bonds
EXW27_02565	COG0439	Biotin carboxylase
EXW27_02570	COG1960	acyl-CoA dehydrogenase activity
EXW27_02580	COG1309	transcriptional regulator
EXW27_02590	COG1131	(ABC) transporter
EXW27_02600	COG1408	metallophosphoesterase
EXW27_02610	COG0823	Involved in the tonB-independent uptake of proteins
EXW27_02615	COG3397	chitin binding
EXW27_02645	COG0697	spore germination
EXW27_02665	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW27_02680	COG2239	Acts as a magnesium transporter
EXW27_02690	COG1114	Component of the transport system for branched-chain amino acids
EXW27_02770	COG2723	6-phospho-beta-galactosidase activity
EXW27_02790	COG1136	(ABC) transporter
EXW27_02810	COG0577	efflux transmembrane transporter activity
EXW27_02815	COG1136	(ABC) transporter
EXW27_02840	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW27_02840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW27_02865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW27_02865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW27_02870	COG1252	NADH dehydrogenase
EXW27_02905	COG0768	penicillin binding
EXW27_02910	COG0768	penicillin binding
EXW27_02920	COG1595	DNA-templated transcription, initiation
EXW27_02930	COG0577	efflux transmembrane transporter activity
EXW27_02935	COG1136	(ABC) transporter
EXW27_02940	COG2205	protein histidine kinase activity
EXW27_02945	COG0745	RESPONSE REGULATOR receiver
EXW27_02950	COG0768	penicillin binding
EXW27_02975	COG1686	Belongs to the peptidase S11 family
EXW27_03005	COG1136	(ABC) transporter
EXW27_03020	COG0110	maltose O-acetyltransferase activity
EXW27_03025	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW27_03045	COG0588	phosphoglycerate mutase activity
EXW27_03055	COG0693	protein deglycase activity
EXW27_03065	COG0500	methyltransferase
EXW27_03065	COG3615	Tellurite resistance protein tehB
EXW27_03070	COG1136	(ABC) transporter
EXW27_03085	COG1309	transcriptional regulator
EXW27_03135	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW27_03145	COG2971	BadF BadG BcrA BcrD
EXW27_03150	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW27_03170	COG1649	PFAM Uncharacterised BCR, COG1649
EXW27_03190	COG1595	DNA-templated transcription, initiation
EXW27_03195	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW27_03230	COG1396	sequence-specific DNA binding
EXW27_03255	COG0189	ligase activity
EXW27_03270	COG1132	(ABC) transporter
EXW27_03275	COG1132	(ABC) transporter
EXW27_03290	COG2258	MOSC domain
EXW27_03295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW27_03300	COG0583	DNA-binding transcription factor activity
EXW27_03315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW27_03320	COG0583	DNA-binding transcription factor activity
EXW27_03330	COG0561	phosphatase activity
EXW27_03365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW27_03375	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW27_03415	COG1247	-acetyltransferase
EXW27_03445	COG1309	transcriptional regulator
EXW27_03450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW27_03465	COG1846	Transcriptional regulator
EXW27_03485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW27_03535	COG1253	flavin adenine dinucleotide binding
EXW27_03560	COG0028	Belongs to the TPP enzyme family
EXW27_03575	COG0596	Alpha beta hydrolase
EXW27_03585	COG1136	(ABC) transporter
EXW27_03595	COG3655	Transcriptional regulator
EXW27_03600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW27_03605	COG1187	pseudouridine synthase activity
EXW27_03615	COG2329	Antibiotic biosynthesis monooxygenase
EXW27_03630	COG1115	amino acid carrier protein
EXW27_03635	COG2318	DinB family
EXW27_03645	COG0776	regulation of translation
EXW27_03660	COG2814	Major facilitator Superfamily
EXW27_03665	COG3251	PFAM MbtH domain protein
EXW27_03670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW27_03675	COG3433	isochorismatase activity
EXW27_03675	COG1535	isochorismatase
EXW27_03680	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW27_03685	COG1169	isochorismate synthase
EXW27_03690	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_03695	COG2223	nitrite transmembrane transporter activity
EXW27_03715	COG0420	3'-5' exonuclease activity
EXW27_03730	COG1024	Enoyl-CoA hydratase
EXW27_03735	COG1280	lysine exporter protein (LysE YggA)
EXW27_03740	COG1012	belongs to the aldehyde dehydrogenase family
EXW27_03745	COG2084	Dehydrogenase
EXW27_03750	COG1960	acyl-CoA dehydrogenase activity
EXW27_03755	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW27_03760	COG2079	MmgE PrpD family protein
EXW27_03765	COG0372	Belongs to the citrate synthase family
EXW27_03785	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW27_03785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW27_03805	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_03835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW27_03890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW27_03895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW27_03900	COG0671	phosphoesterase, PA-phosphatase related
EXW27_03910	COG0515	serine threonine protein kinase
EXW27_03910	COG3064	Membrane
EXW27_03910	COG4991	sh3 domain protein
EXW27_03935	COG4479	Belongs to the UPF0346 family
EXW27_03945	COG1509	lysine 2,3-aminomutase activity
EXW27_03950	COG3829	transcription factor binding
EXW27_03955	COG0456	acetyltransferase
EXW27_03960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW27_03965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW27_03970	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW27_03975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW27_03990	COG5506	Protein of unknown function (DUF1694)
EXW27_03995	COG1012	belongs to the aldehyde dehydrogenase family
EXW27_04000	COG1253	flavin adenine dinucleotide binding
EXW27_04035	COG1174	glycine betaine transport
EXW27_04040	COG0517	IMP dehydrogenase activity
EXW27_04040	COG1125	glycine betaine transport
EXW27_04055	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW27_04065	COG1070	Carbohydrate kinase
EXW27_04080	COG1064	alcohol dehydrogenase
EXW27_04100	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EXW27_04105	COG1737	Transcriptional regulator
EXW27_04110	COG2197	response regulator
EXW27_04115	COG4585	Histidine kinase
EXW27_04115	COG2203	Gaf domain
EXW27_04120	COG0668	transmembrane transport
EXW27_04130	COG1335	isochorismatase
EXW27_04150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW27_04155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW27_04160	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW27_04175	COG0367	asparagine synthase
EXW27_04180	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW27_04185	COG1999	signal sequence binding
EXW27_04190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW27_04205	COG0805	protein transport
EXW27_04210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW27_04215	COG1272	protein, Hemolysin III
EXW27_04220	COG0204	Acyl-transferase
EXW27_04230	COG0768	penicillin binding
EXW27_04245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW27_04260	COG0546	phosphoglycolate phosphatase activity
EXW27_04270	COG4473	ABC transporter
EXW27_04275	COG1131	(ABC) transporter
EXW27_04285	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW27_04290	COG0456	acetyltransferase
EXW27_04300	COG1794	racemase activity, acting on amino acids and derivatives
EXW27_04310	COG2610	gluconate transmembrane transporter activity
EXW27_04335	COG0733	neurotransmitter:sodium symporter activity
EXW27_04340	COG0017	Asparaginyl-tRNA synthetase
EXW27_04400	COG0018	arginyl-trna synthetase
EXW27_04405	COG2136	Putative SAM-dependent methyltransferase
EXW27_04405	COG2521	methyltransferase
EXW27_04420	COG1413	lyase activity
EXW27_04480	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW27_04510	COG0488	(ABC) transporter
EXW27_04515	COG1418	mRNA catabolic process
EXW27_04540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW27_04545	COG0582	viral genome integration into host DNA
EXW27_04590	COG2359	stage V sporulation protein S
EXW27_04620	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW27_04625	COG0714	Associated with various cellular activities
EXW27_04630	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW27_04635	COG1305	Transglutaminase-like
EXW27_04640	COG0386	Belongs to the glutathione peroxidase family
EXW27_04650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW27_04650	COG0426	domain, Protein
EXW27_04675	COG1595	DNA-templated transcription, initiation
EXW27_04680	COG0604	alcohol dehydrogenase
EXW27_04710	COG2226	methyltransferase
EXW27_04735	COG3874	Sporulation protein YtfJ
EXW27_04795	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW27_04830	COG0456	acetyltransferase
EXW27_04855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW27_04860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW27_04865	COG1819	glycosyl
EXW27_04885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW27_04895	COG0561	phosphatase activity
EXW27_04905	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW27_04920	COG2211	Major facilitator Superfamily
EXW27_04935	COG1876	peptidase activity
EXW27_04950	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW27_04970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW27_04975	COG1114	Component of the transport system for branched-chain amino acids
EXW27_05000	COG1253	flavin adenine dinucleotide binding
EXW27_05005	COG2839	Protein conserved in bacteria
EXW27_05010	COG0702	epimerase
EXW27_05030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW27_05040	COG1607	acyl-coa hydrolase
EXW27_05045	COG3689	TIGRFAM TIGR03943 family protein
EXW27_05050	COG0701	Predicted permease
EXW27_05060	COG2244	polysaccharide biosynthetic process
EXW27_05065	COG0586	Pfam SNARE associated Golgi protein
EXW27_05070	COG1051	belongs to the nudix hydrolase family
EXW27_05075	COG5337	Spore coat protein CotH
EXW27_05085	COG0406	alpha-ribazole phosphatase activity
EXW27_05095	COG0346	lactoylglutathione lyase activity
EXW27_05100	COG4166	transmembrane transport
EXW27_05110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW27_05115	COG1902	pentaerythritol trinitrate reductase activity
EXW27_05120	COG2205	protein histidine kinase activity
EXW27_05125	COG0745	RESPONSE REGULATOR receiver
EXW27_05130	COG0577	efflux transmembrane transporter activity
EXW27_05135	COG1136	(ABC) transporter
EXW27_05140	COG2814	Major facilitator Superfamily
EXW27_05160	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW27_05165	COG0456	acetyltransferase
EXW27_05170	COG0523	cobalamin synthesis protein
EXW27_05175	COG4989	oxidoreductase activity
EXW27_05180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW27_05185	COG1231	oxidoreductase activity
EXW27_05195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW27_05210	COG0783	Belongs to the Dps family
EXW27_05215	COG3949	Membrane
EXW27_05260	COG0667	Aldo Keto reductase
EXW27_05265	COG0640	Transcriptional regulator
EXW27_05270	COG1404	Belongs to the peptidase S8 family
EXW27_05275	COG2002	toxin-antitoxin pair type II binding
EXW27_05280	COG0577	efflux transmembrane transporter activity
EXW27_05285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW27_05315	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW27_05325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW27_05330	COG1279	arginine transmembrane transporter activity
EXW27_05335	COG2814	Major facilitator Superfamily
EXW27_05345	COG1082	Xylose isomerase domain protein TIM barrel
EXW27_05355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW27_05375	COG1247	-acetyltransferase
EXW27_05380	COG1285	pathogenesis
EXW27_05405	COG1316	TRANSCRIPTIONal
EXW27_05420	COG0083	homoserine kinase activity
EXW27_05430	COG0460	homoserine dehydrogenase
EXW27_05460	COG4122	O-methyltransferase activity
EXW27_05465	COG0300	oxidoreductase activity
EXW27_05470	COG5002	protein histidine kinase activity
EXW27_05475	COG0745	RESPONSE REGULATOR receiver
EXW27_05480	COG1132	(ABC) transporter
EXW27_05490	COG0791	NLP P60 protein
EXW27_05490	COG1388	LysM domain
EXW27_05505	COG1686	Belongs to the peptidase S11 family
EXW27_05535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW27_05540	COG4988	ABC transporter
EXW27_05545	COG1294	oxidase, subunit
EXW27_05550	COG1271	oxidase subunit
EXW27_05560	COG0346	lactoylglutathione lyase activity
EXW27_05585	COG0583	DNA-binding transcription factor activity
EXW27_05605	COG0411	ABC transporter
EXW27_05620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW27_05625	COG2030	dehydratase
EXW27_05630	COG0318	PFAM AMP-dependent synthetase and ligase
EXW27_05640	COG0523	cobalamin synthesis protein
EXW27_05645	COG1231	oxidoreductase activity
EXW27_05660	COG0628	permease
EXW27_05675	COG0778	Nitroreductase
EXW27_05680	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW27_05685	COG1959	2 iron, 2 sulfur cluster binding
EXW27_05690	COG0583	DNA-binding transcription factor activity
EXW27_05695	COG0697	spore germination
EXW27_05705	COG4549	nuclear export factor GLE1
EXW27_05710	COG2372	response to copper ion
EXW27_05710	COG1276	copper resistance
EXW27_05720	COG4641	Protein conserved in bacteria
EXW27_05730	COG1114	Component of the transport system for branched-chain amino acids
EXW27_05750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW27_05765	COG2132	Multicopper oxidase
EXW27_05770	COG0006	proline dipeptidase activity
EXW27_05790	COG0583	DNA-binding transcription factor activity
EXW27_05805	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW27_05820	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW27_05825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW27_05830	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW27_05840	COG2390	Transcriptional regulator
EXW27_05845	COG4257	antibiotic catabolic process
EXW27_05860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW27_05895	COG0531	amino acid
EXW27_05900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW27_05910	COG1054	Belongs to the UPF0176 family
EXW27_05915	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW27_05925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW27_05930	COG4166	transmembrane transport
EXW27_05970	COG3384	dioxygenase
EXW27_05975	COG2814	Major facilitator Superfamily
EXW27_06000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW27_06005	COG0129	dihydroxy-acid dehydratase activity
EXW27_06020	COG0028	Belongs to the TPP enzyme family
EXW27_06025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW27_06035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW27_06050	COG2323	membrane
EXW27_06055	COG5566	PFAM Mor transcription activator
EXW27_06065	COG0733	neurotransmitter:sodium symporter activity
EXW27_06070	COG2244	polysaccharide biosynthetic process
EXW27_06085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW27_06090	COG2223	nitrite transmembrane transporter activity
EXW27_06095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW27_06105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW27_06110	COG0477	Major facilitator Superfamily
EXW27_06115	COG0640	Transcriptional regulator
EXW27_06120	COG2814	Major facilitator Superfamily
EXW27_06130	COG1695	Transcriptional regulator
EXW27_06155	COG2814	Major facilitator Superfamily
EXW27_06165	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW27_06170	COG1051	belongs to the nudix hydrolase family
EXW27_06225	COG2502	aspartate--ammonia ligase
EXW27_06240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW27_06250	COG1846	Transcriptional regulator
EXW27_06255	COG0784	Response regulator, receiver
EXW27_06260	COG4191	Histidine kinase
EXW27_06265	COG0281	malic enzyme
EXW27_06270	COG1027	Aspartate ammonia-lyase
EXW27_06280	COG0528	UMP kinase activity
EXW27_06285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW27_06300	COG1131	(ABC) transporter
EXW27_06340	COG2733	membrane
EXW27_06345	COG3048	D-serine ammonia-lyase activity
EXW27_06360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW27_06365	COG0785	Cytochrome C biogenesis protein
EXW27_06385	COG3340	Belongs to the peptidase S51 family
EXW27_06390	COG0534	Mate efflux family protein
EXW27_06410	COG0277	FAD linked oxidase domain protein
EXW27_06420	COG1757	Na H antiporter
EXW27_06425	COG1216	Glycosyl transferase, family 2
EXW27_06425	COG0438	transferase activity, transferring glycosyl groups
EXW27_06440	COG0697	spore germination
EXW27_06445	COG1802	Transcriptional regulator
EXW27_06475	COG0367	asparagine synthase
EXW27_06505	COG0406	alpha-ribazole phosphatase activity
EXW27_06555	COG3842	ATPase activity
EXW27_06560	COG0583	DNA-binding transcription factor activity
EXW27_06570	COG2814	Major facilitator Superfamily
EXW27_06585	COG2329	Antibiotic biosynthesis monooxygenase
EXW27_06590	COG0412	Dienelactone hydrolase
EXW27_06620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW27_06625	COG4786	Flagellar basal body rod
EXW27_06630	COG1419	protein localization to endoplasmic reticulum
EXW27_06635	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW27_06640	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW27_06650	COG1987	bacterial-type flagellum assembly
EXW27_06655	COG1338	Plays a role in the flagellum-specific transport system
EXW27_06665	COG1776	CheC inhibitor of MCP methylation
EXW27_06665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW27_06670	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW27_06680	COG0741	lytic transglycosylase activity
EXW27_06685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW27_06690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW27_06695	COG0489	protein tyrosine kinase activity
EXW27_06705	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW27_06710	COG0314	molybdopterin synthase activity
EXW27_06715	COG0303	'Molybdopterin
EXW27_06720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW27_06725	COG2116	formate transmembrane transporter activity
EXW27_06735	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW27_06740	COG5609	conserved protein (DUF2294)
EXW27_06745	COG2427	Protein of unknown function (DUF1641)
EXW27_06750	COG3383	formate dehydrogenase (NAD+) activity
EXW27_06760	COG0861	Integral membrane protein TerC family
EXW27_06785	COG0784	Response regulator, receiver
EXW27_06785	COG0835	chemotaxis
EXW27_06800	COG1749	Flagellar hook protein flgE
EXW27_06820	COG1157	protein secretion by the type III secretion system
EXW27_06830	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW27_06835	COG1766	The M ring may be actively involved in energy transduction
EXW27_06845	COG1558	bacterial-type flagellum-dependent cell motility
EXW27_06850	COG1815	bacterial-type flagellum-dependent cell motility
EXW27_06875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW27_06880	COG1256	bacterial-type flagellum assembly
EXW27_06900	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW27_06915	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW27_06915	COG1776	CheC inhibitor of MCP methylation
EXW27_06920	COG0643	Histidine kinase
EXW27_06920	COG2198	Histidine kinase
EXW27_06925	COG2201	protein-glutamate methylesterase activity
EXW27_06930	COG1360	Flagellar Motor Protein
EXW27_06935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW27_06945	COG1923	regulation of RNA biosynthetic process
EXW27_07000	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW27_07005	COG2323	membrane
EXW27_07015	COG0789	Transcriptional regulator
EXW27_07015	COG4978	Transcriptional regulator
EXW27_07020	COG0475	glutathione-regulated potassium exporter activity
EXW27_07030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW27_07035	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW27_07040	COG3162	membrane
EXW27_07055	COG1280	lysine exporter protein (LysE YggA)
EXW27_07060	COG3403	YqcI/YcgG family
EXW27_07095	COG0328	RNA-DNA hybrid ribonuclease activity
EXW27_07115	COG0454	-acetyltransferase
EXW27_07130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW27_07170	COG2897	thiosulfate sulfurtransferase activity
EXW27_07180	COG0456	acetyltransferase
EXW27_07190	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW27_07195	COG2311	Membrane
EXW27_07200	COG2233	PERMEase
EXW27_07210	COG0024	Methionine aminopeptidase
EXW27_07220	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW27_07225	COG1199	ATP-dependent helicase activity
EXW27_07235	COG0116	Belongs to the methyltransferase superfamily
EXW27_07245	COG3599	regulation of cell shape
EXW27_07250	COG4474	Belongs to the UPF0398 family
EXW27_07285	COG3331	DNA recombination
EXW27_07290	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW27_07290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW27_07300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW27_07305	COG3935	DnaD domain protein
EXW27_07325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW27_07325	COG1199	ATP-dependent helicase activity
EXW27_07335	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW27_07340	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW27_07350	COG0617	tRNA 3'-terminal CCA addition
EXW27_07355	COG0438	transferase activity, transferring glycosyl groups
EXW27_07360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW27_07365	COG1803	Methylglyoxal synthase
EXW27_07370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW27_07375	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW27_07385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW27_07395	COG2738	Putative neutral zinc metallopeptidase
EXW27_07410	COG4347	Protein of unknown function (DUF1405)
EXW27_07430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW27_07445	COG5582	Belongs to the UPF0302 family
EXW27_07450	COG0457	Tetratricopeptide repeat
EXW27_07455	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW27_07465	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW27_07480	COG0142	geranyltranstransferase activity
EXW27_07485	COG2226	methyltransferase
EXW27_07490	COG0142	geranyltranstransferase activity
EXW27_07495	COG0302	gtp cyclohydrolase
EXW27_07505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW27_07525	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW27_07530	COG1160	GTP binding
EXW27_07565	COG1304	FMN binding
EXW27_07575	COG2801	Transposase and inactivated derivatives
EXW27_07585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW27_07590	COG0252	asparaginase activity
EXW27_07595	COG0492	ferredoxin-NADP+ reductase activity
EXW27_07615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW27_07630	COG1408	metallophosphoesterase
EXW27_07640	COG1266	CAAX protease self-immunity
EXW27_07645	COG0514	ATP-dependent DNA helicase (RecQ)
EXW27_07650	COG4955	Helix-turn-helix domain
EXW27_07660	COG1141	Ferredoxin
EXW27_07665	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW27_07675	COG4942	peptidase
EXW27_07680	COG2096	Adenosyltransferase
EXW27_07685	COG5002	protein histidine kinase activity
EXW27_07690	COG0745	RESPONSE REGULATOR receiver
EXW27_07695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW27_07700	COG1333	cytochrome c biogenesis protein
EXW27_07710	COG1187	pseudouridine synthase activity
EXW27_07715	COG0700	Nucleoside recognition
EXW27_07720	COG2715	membrane protein required for spore maturation
EXW27_07725	COG1686	Belongs to the peptidase S11 family
EXW27_07730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW27_07745	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW27_07745	COG0392	lysyltransferase activity
EXW27_07760	COG5002	protein histidine kinase activity
EXW27_07765	COG0582	viral genome integration into host DNA
EXW27_07775	COG1801	Protein of unknown function DUF72
EXW27_07780	COG3852	Histidine kinase
EXW27_07795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW27_07800	COG1392	Phosphate transport regulator
EXW27_07805	COG0306	phosphate transporter
EXW27_07810	COG0730	response to heat
EXW27_07855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW27_07865	COG1114	Component of the transport system for branched-chain amino acids
EXW27_07875	COG2197	response regulator
EXW27_07880	COG4585	Histidine kinase
EXW27_07885	COG4758	membrane
EXW27_07900	COG1757	Na H antiporter
EXW27_07920	COG0733	neurotransmitter:sodium symporter activity
EXW27_07930	COG1648	precorrin-2 dehydrogenase activity
EXW27_07950	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW27_07955	COG0529	Catalyzes the synthesis of activated sulfate
EXW27_07960	COG2046	Belongs to the sulfate adenylyltransferase family
EXW27_07965	COG0175	sulfate reduction
EXW27_07975	COG0019	diaminopimelate decarboxylase activity
EXW27_07985	COG1368	sulfuric ester hydrolase activity
EXW27_07990	COG1183	phosphatidylcholine synthase activity
EXW27_08005	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW27_08010	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW27_08020	COG0107	imidazoleglycerol-phosphate synthase activity
EXW27_08025	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW27_08030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW27_08035	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW27_08045	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW27_08050	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW27_08060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW27_08070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW27_08080	COG0440	acetolactate synthase activity
EXW27_08085	COG0028	Belongs to the TPP enzyme family
EXW27_08090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW27_08115	COG3874	Sporulation protein YtfJ
EXW27_08125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW27_08130	COG1301	dicarboxylic acid transport
EXW27_08140	COG1846	Transcriptional regulator
EXW27_08165	COG0534	Mate efflux family protein
EXW27_08190	COG0716	FMN binding
EXW27_08210	COG1696	Membrane protein involved in D-alanine export
EXW27_08215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW27_08220	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW27_08225	COG2070	2-Nitropropane dioxygenase
EXW27_08230	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW27_08240	COG1335	isochorismatase
EXW27_08250	COG1522	sequence-specific DNA binding
EXW27_08260	COG1266	CAAX protease self-immunity
EXW27_08265	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW27_08270	COG1131	(ABC) transporter
EXW27_08280	COG1131	(ABC) transporter
EXW27_08285	COG1725	Transcriptional regulator
EXW27_08295	COG1012	belongs to the aldehyde dehydrogenase family
EXW27_08300	COG2204	response regulator
EXW27_08315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW27_08320	COG0531	amino acid
EXW27_08325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW27_08340	COG1780	Probably involved in ribonucleotide reductase function
EXW27_08360	COG0456	acetyltransferase
EXW27_08370	COG4873	Protein conserved in bacteria
EXW27_08375	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW27_08385	COG0720	synthase
EXW27_08390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW27_08395	COG5002	protein histidine kinase activity
EXW27_08400	COG2318	DinB family
EXW27_08410	COG1846	Transcriptional regulator
EXW27_08415	COG3852	Histidine kinase
EXW27_08425	COG2861	carbohydrate metabolic process
EXW27_08435	COG0235	Class ii aldolase
EXW27_08445	COG1349	DNA-binding transcription factor activity
EXW27_08455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW27_08460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW27_08470	COG3842	ATPase activity
EXW27_08475	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW27_08490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW27_08500	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW27_08505	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_08525	COG2030	dehydratase
EXW27_08535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW27_08540	COG0861	Integral membrane protein TerC family
EXW27_08545	COG2116	formate transmembrane transporter activity
EXW27_08555	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW27_08560	COG1556	Lactate utilization protein
EXW27_08565	COG1139	Iron-sulfur cluster binding protein
EXW27_08570	COG0247	lactate metabolic process
EXW27_08575	COG2186	Transcriptional regulator
EXW27_08580	COG5002	protein histidine kinase activity
EXW27_08585	COG0745	RESPONSE REGULATOR receiver
EXW27_08595	COG3835	regulator
EXW27_08600	COG0277	FAD linked oxidase domain protein
EXW27_08605	COG0247	lactate metabolic process
EXW27_08610	COG2340	Cysteine-rich secretory protein family
EXW27_08620	COG0564	pseudouridine synthase activity
EXW27_08630	COG2409	Drug exporters of the RND superfamily
EXW27_08640	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW27_08645	COG1177	transmembrane transport
EXW27_08650	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW27_08660	COG1012	belongs to the aldehyde dehydrogenase family
EXW27_08695	COG0681	Belongs to the peptidase S26 family
EXW27_08700	COG1686	Belongs to the peptidase S11 family
EXW27_08720	COG1668	transmembrane transport
EXW27_08725	COG4152	abc transporter atp-binding protein
EXW27_08750	COG1476	TRANSCRIPTIONal
EXW27_08755	COG0567	Dehydrogenase, E1 component
EXW27_08760	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW27_08890	COG5634	Uncharacterized conserved protein (DUF2278)
EXW27_08895	COG1620	l-lactate permease
EXW27_08905	COG0159	tryptophan synthase activity
EXW27_08910	COG0133	tryptophan synthase activity
EXW27_08915	COG0135	phosphoribosylanthranilate isomerase activity
EXW27_08920	COG0134	indole-3-glycerol-phosphate synthase activity
EXW27_08925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW27_08930	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW27_08930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW27_08945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW27_08950	COG5492	domain, Protein
EXW27_08975	COG2382	esterase
EXW27_08980	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW27_08985	COG2153	protein acetylation
EXW27_09030	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW27_09045	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW27_09065	COG0457	Tetratricopeptide repeat
EXW27_09065	COG0463	Glycosyl transferase, family 2
EXW27_09085	COG1216	Glycosyl transferase, family 2
EXW27_09090	COG0772	Belongs to the SEDS family
EXW27_09095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW27_09105	COG0564	pseudouridine synthase activity
EXW27_09115	COG2357	RelA SpoT domain protein
EXW27_09125	COG4116	CYTH
EXW27_09130	COG2346	COG2346, Truncated hemoglobins
EXW27_09140	COG1164	Oligoendopeptidase f
EXW27_09150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW27_09155	COG4862	establishment of competence for transformation
EXW27_09160	COG0861	Integral membrane protein TerC family
EXW27_09180	COG4166	transmembrane transport
EXW27_09185	COG0534	Mate efflux family protein
EXW27_09190	COG4608	Belongs to the ABC transporter superfamily
EXW27_09195	COG0444	Belongs to the ABC transporter superfamily
EXW27_09200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW27_09205	COG0601	transmembrane transport
EXW27_09210	COG4166	transmembrane transport
EXW27_09225	COG0180	Tryptophanyl-tRNA synthetase
EXW27_09240	COG5504	Zn-dependent protease
EXW27_09245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW27_09250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW27_09265	COG2267	carboxylic ester hydrolase activity
EXW27_09285	COG0561	phosphatase activity
EXW27_09300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW27_09310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW27_09320	COG2996	Protein conserved in bacteria
EXW27_09325	COG1666	GTP binding
EXW27_09335	COG0004	ammonium transporteR
EXW27_09340	COG0753	catalase activity
EXW27_09350	COG0367	asparagine synthase
EXW27_09375	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW27_09425	COG1074	ATP-dependent DNA helicase activity
EXW27_09430	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW27_09440	COG0398	Pfam SNARE associated Golgi protein
EXW27_09445	COG4903	ComK protein
EXW27_09465	COG1278	Cold shock
EXW27_09475	COG2224	Isocitrate lyase
EXW27_09480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW27_09510	COG0697	spore germination
EXW27_09515	COG0501	Belongs to the peptidase M48B family
EXW27_09535	COG0745	RESPONSE REGULATOR receiver
EXW27_09540	COG2205	protein histidine kinase activity
EXW27_09545	COG2207	Transcriptional regulator
EXW27_09545	COG3708	Transcriptional regulator
EXW27_09555	COG1595	DNA-templated transcription, initiation
EXW27_09565	COG1078	dGTPase activity
EXW27_09570	COG1408	metallophosphoesterase
EXW27_09585	COG4208	sulfate ABC transporter
EXW27_09590	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW27_09595	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW27_09610	COG0318	PFAM AMP-dependent synthetase and ligase
EXW27_09620	COG0095	Lipoate-protein ligase
EXW27_09625	COG1234	tRNA 3'-trailer cleavage
EXW27_09635	COG1609	Transcriptional regulator
EXW27_09675	COG1511	domain protein
EXW27_09680	COG1309	transcriptional regulator
EXW27_09700	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW27_09705	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW27_09710	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW27_09715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW27_09720	COG2329	Antibiotic biosynthesis monooxygenase
EXW27_09725	COG3428	Bacterial PH domain
EXW27_09730	COG3402	PFAM membrane-flanked domain
EXW27_09745	COG3428	Bacterial PH domain
EXW27_09750	COG3402	PFAM membrane-flanked domain
EXW27_09765	COG1556	Lactate utilization protein
EXW27_09770	COG1139	Iron-sulfur cluster binding protein
EXW27_09775	COG0247	lactate metabolic process
EXW27_09785	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW27_09790	COG0531	amino acid
EXW27_09810	COG4473	ABC transporter
EXW27_09815	COG1131	(ABC) transporter
EXW27_09820	COG0537	adenosine 5'-monophosphoramidase activity
EXW27_09830	COG1846	Transcriptional regulator
EXW27_09845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW27_09850	COG3973	AAA domain
EXW27_09865	COG1595	DNA-templated transcription, initiation
EXW27_09885	COG1695	Transcriptional regulator
EXW27_09890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW27_09895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW27_09900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW27_09905	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW27_09910	COG3620	sequence-specific DNA binding
EXW27_09915	COG2140	Oxalate decarboxylase
EXW27_09925	COG2267	carboxylic ester hydrolase activity
EXW27_09935	COG0457	Tetratricopeptide repeat
EXW27_09940	COG0346	lactoylglutathione lyase activity
EXW27_09945	COG0346	lactoylglutathione lyase activity
EXW27_09955	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW27_09960	COG4717	serine-type aminopeptidase activity
EXW27_09965	COG0420	3'-5' exonuclease activity
EXW27_09995	COG2197	response regulator
EXW27_10000	COG4585	Histidine kinase
EXW27_10010	COG2186	Transcriptional regulator
EXW27_10015	COG2807	transmembrane transport
EXW27_10040	COG5002	protein histidine kinase activity
EXW27_10040	COG2205	protein histidine kinase activity
EXW27_10040	COG0784	Response regulator, receiver
EXW27_10045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW27_10050	COG2208	phosphoserine phosphatase activity
EXW27_10060	COG1191	sigma factor activity
EXW27_10065	COG2172	sigma factor antagonist activity
EXW27_10085	COG3237	CsbD-like
EXW27_10105	COG0825	malonyl-CoA metabolic process
EXW27_10115	COG4932	domain protein
EXW27_10115	COG3266	domain, Protein
EXW27_10115	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EXW27_10120	COG2318	DinB family
EXW27_10125	COG2378	regulation of single-species biofilm formation
EXW27_10140	COG0582	viral genome integration into host DNA
EXW27_10155	COG4085	toxin activity
EXW27_10155	COG0737	Belongs to the 5'-nucleotidase family
EXW27_10155	COG1525	nuclease
EXW27_10180	COG0076	glutamate decarboxylase activity
EXW27_10200	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW27_10205	COG1335	isochorismatase
EXW27_10220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW27_10235	COG2376	Dihydroxyacetone kinase
EXW27_10250	COG2376	Dihydroxyacetone kinase
EXW27_10270	COG0640	Transcriptional regulator
EXW27_10275	COG2814	Major facilitator Superfamily
EXW27_10340	COG1183	phosphatidylcholine synthase activity
EXW27_10350	COG0456	acetyltransferase
EXW27_10355	COG2723	6-phospho-beta-galactosidase activity
EXW27_10360	COG1263	PTS System
EXW27_10360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW27_10360	COG2190	(PTS) system
EXW27_10365	COG3711	transcriptional antiterminator
EXW27_10400	COG0477	Major facilitator Superfamily
EXW27_10430	COG0305	Participates in initiation and elongation during chromosome replication
EXW27_10455	COG3181	Tripartite tricarboxylate transporter family receptor
EXW27_10460	COG4565	transcriptional regulatory protein
EXW27_10465	COG3290	protein histidine kinase activity
EXW27_10470	COG0477	Major facilitator Superfamily
EXW27_10620	COG4608	Belongs to the ABC transporter superfamily
EXW27_10625	COG0444	Belongs to the ABC transporter superfamily
EXW27_10630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW27_10635	COG0601	transmembrane transport
EXW27_10670	COG0579	oxidoreductase
EXW27_10690	COG2318	DinB family
EXW27_10700	COG2801	Transposase and inactivated derivatives
EXW27_10715	COG1363	Peptidase, m42
EXW27_10730	COG1024	Enoyl-CoA hydratase
EXW27_10745	COG1696	Membrane protein involved in D-alanine export
EXW27_10765	COG2244	polysaccharide biosynthetic process
EXW27_10770	COG0653	protein targeting
EXW27_10775	COG0659	secondary active sulfate transmembrane transporter activity
EXW27_10785	COG0318	PFAM AMP-dependent synthetase and ligase
EXW27_10790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW27_10800	COG0561	phosphatase activity
EXW27_10805	COG2094	Belongs to the DNA glycosylase MPG family
EXW27_10810	COG1216	Glycosyl transferase, family 2
EXW27_10815	COG0463	Glycosyl transferase, family 2
EXW27_10820	COG3527	Alpha-acetolactate decarboxylase
EXW27_10825	COG0028	Belongs to the TPP enzyme family
EXW27_10840	COG2801	Transposase and inactivated derivatives
EXW27_10850	COG3679	Belongs to the UPF0342 family
EXW27_10855	COG4399	Belongs to the UPF0754 family
EXW27_10865	COG0189	ligase activity
EXW27_10880	COG1126	abc transporter atp-binding protein
EXW27_10885	COG0765	amino acid transport
EXW27_10890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW27_10895	COG1132	(ABC) transporter
EXW27_10900	COG1132	(ABC) transporter
EXW27_10920	COG0531	amino acid
EXW27_10935	COG2814	Major facilitator Superfamily
EXW27_10940	COG4533	DNA binding
EXW27_10950	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW27_10960	COG1733	regulation of RNA biosynthetic process
EXW27_10965	COG2814	Major facilitator Superfamily
EXW27_10970	COG1309	transcriptional regulator
EXW27_10975	COG2076	Multidrug Resistance protein
EXW27_10990	COG0300	oxidoreductase activity
EXW27_11000	COG1522	sequence-specific DNA binding
EXW27_11005	COG0697	spore germination
EXW27_11025	COG2259	Doxx family
EXW27_11035	COG1263	PTS System
EXW27_11035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW27_11040	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW27_11045	COG1737	Transcriptional regulator
EXW27_11055	COG0475	glutathione-regulated potassium exporter activity
EXW27_11060	COG0531	amino acid
EXW27_11095	COG0586	Pfam SNARE associated Golgi protein
EXW27_11125	COG3546	catalase activity
EXW27_11130	COG1114	Component of the transport system for branched-chain amino acids
EXW27_11145	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW27_11155	COG1136	(ABC) transporter
EXW27_11160	COG0577	efflux transmembrane transporter activity
EXW27_11165	COG1388	LysM domain
EXW27_11165	COG3584	3D domain protein
EXW27_11190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW27_11195	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW27_11200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW27_11200	COG3711	transcriptional antiterminator
EXW27_11215	COG2814	Major facilitator Superfamily
EXW27_11220	COG0604	alcohol dehydrogenase
EXW27_11225	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW27_11230	COG0604	alcohol dehydrogenase
EXW27_11235	COG1316	TRANSCRIPTIONal
EXW27_11245	COG0730	response to heat
EXW27_11250	COG2210	Belongs to the sulfur carrier protein TusA family
EXW27_11255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW27_11255	COG0425	Belongs to the sulfur carrier protein TusA family
EXW27_11260	COG0425	Belongs to the sulfur carrier protein TusA family
EXW27_11265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW27_11265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW27_11270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW27_11270	COG0425	Belongs to the sulfur carrier protein TusA family
EXW27_11275	COG1937	Protein conserved in bacteria
EXW27_11295	COG2719	SpoVR family
EXW27_11300	COG0778	Nitroreductase
EXW27_11350	COG1609	Transcriptional regulator
EXW27_11355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW27_11355	COG1263	PTS System
EXW27_11360	COG1621	beta-fructofuranosidase activity
EXW27_11365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW27_11380	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_11385	COG2252	PERMEase
EXW27_11390	COG1879	ABC-type sugar transport system periplasmic component
EXW27_11395	COG1129	ABC transporter
EXW27_11400	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW27_11420	COG1846	Transcriptional regulator
EXW27_11425	COG2814	Major facilitator Superfamily
EXW27_11430	COG2205	protein histidine kinase activity
EXW27_11435	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW27_11440	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW27_11445	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW27_11470	COG0351	phosphomethylpyrimidine kinase
EXW27_11475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW27_11480	COG2022	thiamine diphosphate biosynthetic process
EXW27_11485	COG2104	thiamine diphosphate biosynthetic process
EXW27_11490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW27_11495	COG0352	thiamine-phosphate diphosphorylase activity
EXW27_11500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW27_11505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW27_11510	COG1116	anion transmembrane transporter activity
EXW27_11515	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW27_11520	COG3103	Sh3 type 3 domain protein
EXW27_11520	COG4991	sh3 domain protein
EXW27_11520	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW27_11535	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW27_11655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW27_11665	COG0581	inorganic phosphate transmembrane transporter activity
EXW27_11670	COG0573	inorganic phosphate transmembrane transporter activity
EXW27_11675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW27_11685	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW27_11690	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW27_11700	COG0531	amino acid
EXW27_11705	COG0697	spore germination
EXW27_11710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW27_11725	COG4990	cell redox homeostasis
EXW27_11730	COG0833	amino acid
EXW27_11740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW27_11745	COG1845	cytochrome c oxidase, subunit III
EXW27_11760	COG0475	glutathione-regulated potassium exporter activity
EXW27_11760	COG0569	domain protein
EXW27_11770	COG2153	protein acetylation
EXW27_11785	COG2252	PERMEase
EXW27_11790	COG1113	amino acid transport
EXW27_11805	COG1114	Component of the transport system for branched-chain amino acids
EXW27_11810	COG3104	oligopeptide transport
EXW27_11830	COG1476	TRANSCRIPTIONal
EXW27_11835	COG3583	domain protein
EXW27_11835	COG3584	3D domain protein
EXW27_11840	COG0840	transmembrane signaling receptor activity
EXW27_11870	COG3568	Endonuclease Exonuclease Phosphatase
EXW27_11885	COG1063	alcohol dehydrogenase
EXW27_11915	COG1879	ABC-type sugar transport system periplasmic component
EXW27_11920	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW27_11930	COG1869	D-ribose catabolic process
EXW27_11935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW27_11940	COG1609	Transcriptional regulator
EXW27_11945	COG0477	Major facilitator Superfamily
EXW27_11950	COG1846	Transcriptional regulator
EXW27_11955	COG2271	Major facilitator Superfamily
EXW27_11970	COG0659	secondary active sulfate transmembrane transporter activity
EXW27_11985	COG5002	protein histidine kinase activity
EXW27_11990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW27_11995	COG2378	regulation of single-species biofilm formation
EXW27_12005	COG0833	amino acid
EXW27_12010	COG0765	amino acid transport
EXW27_12015	COG0765	amino acid transport
EXW27_12020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW27_12025	COG1126	abc transporter atp-binding protein
EXW27_12030	COG1115	amino acid carrier protein
EXW27_12035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW27_12050	COG1404	Belongs to the peptidase S8 family
EXW27_12055	COG2197	response regulator
EXW27_12060	COG4585	Histidine kinase
EXW27_12065	COG0697	spore germination
EXW27_12080	COG0366	Alpha amylase catalytic
EXW27_12085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW27_12085	COG1263	PTS System
EXW27_12090	COG2188	Transcriptional regulator
EXW27_12095	COG0531	amino acid
EXW27_12115	COG0714	Associated with various cellular activities
EXW27_12120	COG4548	von Willebrand factor, type A
EXW27_12130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW27_12135	COG0156	8-amino-7-oxononanoate synthase activity
EXW27_12150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW27_12155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW27_12160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW27_12165	COG3104	oligopeptide transport
EXW27_12185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW27_12190	COG1620	l-lactate permease
EXW27_12195	COG1027	Aspartate ammonia-lyase
EXW27_12200	COG1253	flavin adenine dinucleotide binding
EXW27_12205	COG0346	lactoylglutathione lyase activity
EXW27_12210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW27_12215	COG1316	TRANSCRIPTIONal
EXW27_12220	COG2720	vancomycin resistance protein
EXW27_12240	COG3227	Zinc metalloprotease (Elastase)
EXW27_12250	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW27_12255	COG2217	Heavy metal translocating P-type atpase
EXW27_12260	COG0640	Transcriptional regulator
EXW27_12270	COG0531	amino acid
EXW27_12285	COG2427	Protein of unknown function (DUF1641)
EXW27_12290	COG3383	formate dehydrogenase (NAD+) activity
EXW27_12295	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW27_12300	COG0456	acetyltransferase
EXW27_12305	COG0745	RESPONSE REGULATOR receiver
EXW27_12310	COG5002	protein histidine kinase activity
EXW27_12320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW27_12325	COG0697	spore germination
EXW27_12335	COG0281	malic enzyme
EXW27_12340	COG3493	citrate carrier protein
EXW27_12345	COG4565	transcriptional regulatory protein
EXW27_12350	COG3290	protein histidine kinase activity
EXW27_12360	COG4990	cell redox homeostasis
EXW27_12370	COG5002	protein histidine kinase activity
EXW27_12375	COG0745	RESPONSE REGULATOR receiver
EXW27_12380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW27_12390	COG0395	ABC-type sugar transport system, permease component
EXW27_12395	COG1175	transmembrane transport
EXW27_12400	COG3842	ATPase activity
EXW27_12405	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW27_12430	COG2851	Citrate transporter
EXW27_12435	COG4565	transcriptional regulatory protein
EXW27_12440	COG3290	protein histidine kinase activity
EXW27_12450	COG2268	Band 7 protein
EXW27_12455	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW27_12470	COG2718	Belongs to the UPF0229 family
EXW27_12475	COG2766	serine protein kinase
EXW27_12485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW27_12505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW27_12510	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW27_12630	COG0735	belongs to the Fur family
EXW27_12635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW27_12655	COG4555	ABC transporter
EXW27_12660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW27_12665	COG0067	glutamate synthase
EXW27_12665	COG0069	glutamate synthase activity
EXW27_12665	COG0070	glutamate synthase
EXW27_12675	COG4129	membrane
EXW27_12680	COG1132	(ABC) transporter
EXW27_12685	COG3557	Belongs to the UPF0374 family
EXW27_12700	COG1194	a g-specific adenine glycosylase
EXW27_12705	COG1988	membrane-bound metal-dependent
EXW27_12730	COG2137	regulation of response to DNA damage stimulus
EXW27_12735	COG1090	epimerase
EXW27_12740	COG1228	amidohydrolase
EXW27_12755	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW27_12760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW27_12775	COG0463	Glycosyl transferase, family 2
EXW27_12780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW27_12780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW27_12790	COG1216	Glycosyl transferase, family 2
EXW27_12810	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW27_12815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW27_12815	COG1263	PTS System
EXW27_12825	COG2066	Belongs to the glutaminase family
EXW27_12845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW27_12850	COG0833	amino acid
EXW27_12860	COG3829	transcription factor binding
EXW27_12880	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW27_12900	COG0535	radical SAM domain protein
EXW27_12910	COG0387	Pfam Sodium calcium exchanger
EXW27_12915	COG3871	stress protein (general stress protein 26)
EXW27_12930	COG0586	Pfam SNARE associated Golgi protein
EXW27_12950	COG0697	spore germination
EXW27_12955	COG2217	Heavy metal translocating P-type atpase
EXW27_12960	COG1295	ribonuclease BN
EXW27_12970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW27_12975	COG4840	Belongs to the UPF0435 family
EXW27_12985	COG3853	Toxic anion resistance protein (TelA)
EXW27_12995	COG0861	Integral membrane protein TerC family
EXW27_13000	COG2310	stress, protein
EXW27_13005	COG2310	stress, protein
EXW27_13010	COG2310	stress, protein
EXW27_13040	COG2270	Major facilitator Superfamily
EXW27_13085	COG0488	(ABC) transporter
EXW27_13090	COG1116	anion transmembrane transporter activity
EXW27_13095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW27_13100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW27_13115	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW27_13120	COG0352	thiamine-phosphate diphosphorylase activity
EXW27_13125	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW27_13140	COG2801	Transposase and inactivated derivatives
EXW27_13155	COG1263	PTS System
EXW27_13155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW27_13155	COG2190	(PTS) system
EXW27_13160	COG0366	Alpha amylase catalytic
EXW27_13165	COG0277	FAD linked oxidase domain protein
EXW27_13170	COG0840	transmembrane signaling receptor activity
EXW27_13180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW27_13185	COG0765	amino acid transport
EXW27_13195	COG0723	plastoquinol--plastocyanin reductase activity
EXW27_13195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW27_13200	COG2814	Major facilitator Superfamily
EXW27_13210	COG3541	Predicted nucleotidyltransferase
EXW27_13230	COG5002	protein histidine kinase activity
EXW27_13255	COG0166	Belongs to the GPI family
EXW27_13270	COG0492	ferredoxin-NADP+ reductase activity
EXW27_13280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW27_13285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW27_13290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW27_13300	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW27_13310	COG0450	alkyl hydroperoxide reductase
EXW27_13325	COG1473	amidohydrolase
EXW27_13330	COG1757	Na H antiporter
EXW27_13355	COG4807	Protein conserved in bacteria
EXW27_13360	COG5002	protein histidine kinase activity
EXW27_13365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW27_13375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW27_13390	COG2309	aminopeptidase activity
EXW27_13395	COG2076	Multidrug Resistance protein
EXW27_13400	COG1012	belongs to the aldehyde dehydrogenase family
EXW27_13410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW27_13415	COG0546	phosphoglycolate phosphatase activity
EXW27_13420	COG1597	lipid kinase activity
EXW27_13425	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW27_13430	COG0154	amidase activity
EXW27_13440	COG4682	membrane
EXW27_13445	COG1846	Transcriptional regulator
EXW27_13450	COG0003	Pfam Anion-transporting ATPase
EXW27_13465	COG1464	Belongs to the NlpA lipoprotein family
EXW27_13470	COG2011	ABC-type metal ion transport system permease component
EXW27_13480	COG1335	isochorismatase
EXW27_13485	COG1012	belongs to the aldehyde dehydrogenase family
EXW27_13495	COG4851	CamS sex pheromone cAM373 precursor
EXW27_13500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW27_13505	COG0210	DNA helicase
EXW27_13510	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW27_13530	COG0151	Belongs to the GarS family
EXW27_13535	COG0138	bifunctional purine biosynthesis protein purh
EXW27_13540	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW27_13545	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW27_13550	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW27_13555	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW27_13560	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW27_13565	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW27_13570	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW27_13575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW27_13580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW27_13585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW27_13615	COG0697	spore germination
EXW27_13640	COG0745	RESPONSE REGULATOR receiver
EXW27_13645	COG2205	protein histidine kinase activity
EXW27_13710	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW27_13735	COG5002	protein histidine kinase activity
EXW27_13745	COG2252	PERMEase
EXW27_13750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW27_13750	COG0519	Catalyzes the synthesis of GMP from XMP
EXW27_13755	COG0459	protein refolding
EXW27_13760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW27_13765	COG1266	CAAX protease self-immunity
EXW27_13775	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW27_13780	COG0488	(ABC) transporter
EXW27_13790	COG0456	acetyltransferase
EXW27_13795	COG1214	PFAM Peptidase M22, glycoprotease
EXW27_13800	COG0802	atpase or kinase
EXW27_13900	COG2183	response to ionizing radiation
EXW27_13905	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW27_13910	COG0864	Transcriptional regulator
EXW27_13920	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW27_13925	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW27_13930	COG0705	Rhomboid family
EXW27_13935	COG4294	response to UV
EXW27_13945	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW27_13955	COG2814	Major facilitator Superfamily
EXW27_13960	COG0531	amino acid
EXW27_13970	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW27_13975	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW27_14010	COG0561	phosphatase activity
EXW27_14015	COG4608	Belongs to the ABC transporter superfamily
EXW27_14020	COG0444	Belongs to the ABC transporter superfamily
EXW27_14025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW27_14030	COG0601	transmembrane transport
EXW27_14040	COG0747	negative chemotaxis
EXW27_14050	COG0842	Transport permease protein
EXW27_14055	COG0842	Transport permease protein
EXW27_14055	COG1511	domain protein
EXW27_14060	COG1131	(ABC) transporter
EXW27_14065	COG2197	response regulator
EXW27_14070	COG4585	Histidine kinase
EXW27_14075	COG0488	(ABC) transporter
EXW27_14100	COG5298	Protein conserved in bacteria
EXW27_14115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW27_14125	COG1609	Transcriptional regulator
EXW27_14135	COG0204	Acyl-transferase
EXW27_14150	COG0697	spore germination
EXW27_14165	COG1910	domain protein
EXW27_14170	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW27_14175	COG4149	molybdate abc transporter
EXW27_14190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW27_14195	COG0656	L-ascorbic acid biosynthetic process
EXW27_14200	COG4166	transmembrane transport
EXW27_14205	COG4166	transmembrane transport
EXW27_14220	COG2207	Transcriptional regulator
EXW27_14230	COG4166	transmembrane transport
EXW27_14235	COG4608	Belongs to the ABC transporter superfamily
EXW27_14240	COG0444	Belongs to the ABC transporter superfamily
EXW27_14245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW27_14250	COG0601	transmembrane transport
EXW27_14270	COG2814	Major facilitator Superfamily
EXW27_14280	COG2271	Major facilitator Superfamily
EXW27_14285	COG0277	FAD linked oxidase domain protein
EXW27_14295	COG0604	alcohol dehydrogenase
EXW27_14300	COG1464	Belongs to the NlpA lipoprotein family
EXW27_14310	COG2011	ABC-type metal ion transport system permease component
EXW27_14315	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_14345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW27_14350	COG4856	YbbR-like protein
EXW27_14355	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW27_14435	COG0726	polysaccharide deacetylase
EXW27_14440	COG2194	sulfuric ester hydrolase activity
EXW27_14450	COG0489	protein tyrosine kinase activity
EXW27_14455	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW27_14465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW27_14470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW27_14480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW27_14505	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW27_14510	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW27_14515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW27_14525	COG0024	Methionine aminopeptidase
EXW27_14530	COG0563	adenylate kinase activity
EXW27_14535	COG0201	protein transport
EXW27_14540	COG0200	Binds to the 23S rRNA
EXW27_14545	COG1841	ribosomal large subunit assembly
EXW27_14555	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW27_14565	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW27_14575	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW27_14580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW27_14590	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW27_14595	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW27_14610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW27_14615	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW27_14620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW27_14625	COG0089	rRNA binding
EXW27_14630	COG0088	Forms part of the polypeptide exit tunnel
EXW27_14635	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW27_14640	COG0051	transcription antitermination factor activity, RNA binding
EXW27_14645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW27_14650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW27_14660	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW27_14665	COG1358	cellular component organization or biogenesis
EXW27_14670	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW27_14675	COG0085	RNA polymerase activity
EXW27_14680	COG2813	Specifically methylates the guanine in position
EXW27_14685	COG0222	ribosome binding
EXW27_14690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW27_14695	COG0081	regulation of translation
EXW27_14700	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW27_14705	COG0250	Participates in transcription elongation, termination and antitermination
EXW27_14710	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW27_14715	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW27_14725	COG3688	RNA-binding protein containing a PIN domain
EXW27_14730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW27_14740	COG0215	cysteine-tRNA ligase activity
EXW27_14745	COG1045	serine acetyltransferase
EXW27_14750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW27_14760	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW27_14765	COG4956	integral membrane protein (PIN domain superfamily)
EXW27_14770	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW27_14775	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW27_14780	COG0542	response to heat
EXW27_14785	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW27_14790	COG3880	PFAM UvrB UvrC protein
EXW27_14875	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW27_14880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW27_14885	COG1396	sequence-specific DNA binding
EXW27_14890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW27_14895	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW27_14900	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW27_14905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW27_14910	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW27_14915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW27_14920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW27_14925	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW27_14930	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW27_14935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW27_14940	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW27_14950	COG2208	phosphoserine phosphatase activity
EXW27_14965	COG1098	S1 RNA binding domain
EXW27_14985	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW27_14990	COG3956	TIGRFAM MazG family protein
EXW27_14995	COG2244	polysaccharide biosynthetic process
EXW27_15000	COG2002	toxin-antitoxin pair type II binding
EXW27_15005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW27_15025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW27_15030	COG2088	sporulation resulting in formation of a cellular spore
EXW27_15035	COG0251	oxidation-reduction process
EXW27_15040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW27_15045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW27_15055	COG4466	Protein conserved in bacteria
EXW27_15065	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW27_15075	COG0084	hydrolase, TatD family'
EXW27_15085	COG2002	toxin-antitoxin pair type II binding
EXW27_15090	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW27_15100	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW27_15105	COG4467	Involved in initiation control of chromosome replication
EXW27_15110	COG1774	PSP1 C-terminal conserved region
EXW27_15115	COG0470	DNA polymerase III
EXW27_15120	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW27_15125	COG1982	Orn Lys Arg decarboxylase major
EXW27_15170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW27_15175	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW27_15180	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW27_15190	COG0590	tRNA wobble adenosine to inosine editing
EXW27_15195	COG1335	isochorismatase
EXW27_15200	COG1428	Deoxynucleoside kinase
EXW27_15205	COG1428	Deoxynucleoside kinase
EXW27_15225	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW27_15230	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW27_15235	COG1686	Belongs to the peptidase S11 family
EXW27_15240	COG0517	IMP dehydrogenase activity
EXW27_15240	COG0516	GMP reductase activity
EXW27_15275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW27_15280	COG0187	DNA topoisomerase II activity
EXW27_15285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW27_15290	COG2501	S4 domain
EXW27_15295	COG0592	DNA-directed DNA polymerase activity
EXW27_15300	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW27_15305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW27_15310	COG0594	ribonuclease P activity
EXW27_15315	COG0706	membrane insertase activity
EXW27_15320	COG1847	R3H domain protein
EXW27_15325	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW27_15330	COG0445	tRNA wobble uridine modification
EXW27_15335	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW27_15340	COG1475	DNA binding
EXW27_15345	COG1192	Involved in chromosome partitioning
EXW27_15350	COG1475	DNA binding
EXW27_15360	COG0668	transmembrane transport
EXW27_15365	COG4481	Protein conserved in bacteria
EXW27_15370	COG0012	GTP binding
EXW27_15375	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW27_15380	COG0629	single-stranded DNA binding
EXW27_15390	COG4241	membrane
EXW27_15395	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW27_15400	COG0359	binds to the 23S rRNA
EXW27_15405	COG0305	Participates in initiation and elongation during chromosome replication
EXW27_15435	COG0745	RESPONSE REGULATOR receiver
EXW27_15440	COG5002	protein histidine kinase activity
EXW27_15450	COG4853	Protein conserved in bacteria
EXW27_15455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW27_15460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW27_15470	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW27_15480	COG1164	Oligoendopeptidase f
EXW27_15505	COG1272	protein, Hemolysin III
EXW27_15510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW27_15560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW27_15570	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW27_15575	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW27_15580	COG2814	Major facilitator Superfamily
EXW27_15585	COG3275	phosphorelay sensor kinase activity
EXW27_15590	COG3279	Response regulator of the LytR AlgR family
EXW27_15595	COG1380	Effector of murein hydrolase LrgA
EXW27_15605	COG0628	permease
EXW27_15610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW27_15610	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW27_15615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW27_15620	COG1309	transcriptional regulator
EXW27_15625	COG0488	(ABC) transporter
EXW27_15635	COG1216	Glycosyl transferase, family 2
EXW27_15650	COG1216	Glycosyl transferase, family 2
EXW27_15655	COG1607	acyl-coa hydrolase
EXW27_15665	COG0840	transmembrane signaling receptor activity
EXW27_15690	COG0477	Major facilitator Superfamily
EXW27_15695	COG3279	Response regulator of the LytR AlgR family
EXW27_15700	COG1966	Carbon starvation protein
EXW27_15705	COG2879	small protein
EXW27_15710	COG3706	GGDEF domain
EXW27_15715	COG0351	phosphomethylpyrimidine kinase
EXW27_15720	COG2203	Gaf domain
EXW27_15720	COG4585	Histidine kinase
EXW27_15725	COG2197	response regulator
EXW27_15745	COG2873	o-acetylhomoserine
EXW27_15750	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW27_15755	COG0460	homoserine dehydrogenase
EXW27_15765	COG1609	Transcriptional regulator
EXW27_15770	COG2755	lipolytic protein G-D-S-L family
EXW27_15775	COG1131	(ABC) transporter
EXW27_15780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW27_15785	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW27_15790	COG2814	Major facilitator Superfamily
EXW27_15795	COG0561	phosphatase activity
EXW27_15800	COG2233	PERMEase
EXW27_15815	COG2363	Small membrane protein
EXW27_15825	COG3773	Cell wall hydrolase
EXW27_15835	COG3253	May function as heme-dependent peroxidase
EXW27_15840	COG0280	phosphate acetyltransferase
EXW27_15855	COG4844	belongs to the
EXW27_15860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW27_15865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW27_15870	COG1120	ATPase activity
EXW27_15875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW27_15880	COG1078	dGTPase activity
EXW27_15890	COG1994	Peptidase M50
EXW27_15900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW27_15905	COG0584	glycerophosphoryl diester phosphodiesterase
EXW27_15910	COG0789	Transcriptional regulator
EXW27_15915	COG2814	Major facilitator Superfamily
EXW27_15920	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW27_15925	COG0010	Belongs to the arginase family
EXW27_15940	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW27_15945	COG4506	Protein conserved in bacteria
EXW27_15960	COG2234	aminopeptidase activity
EXW27_15965	COG0024	Methionine aminopeptidase
EXW27_15970	COG1131	(ABC) transporter
EXW27_15975	COG0842	Transport permease protein
EXW27_15980	COG4585	Histidine kinase
EXW27_15985	COG2197	response regulator
EXW27_15990	COG3227	Zinc metalloprotease (Elastase)
EXW27_16005	COG5001	Diguanylate cyclase
EXW27_16005	COG3300	MHYT domain
EXW27_16010	COG4294	response to UV
EXW27_16015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW27_16020	COG0247	lactate metabolic process
EXW27_16020	COG2181	nitrate reductase activity
EXW27_16025	COG0183	Belongs to the thiolase family
EXW27_16030	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW27_16035	COG1960	acyl-CoA dehydrogenase activity
EXW27_16040	COG1960	acyl-CoA dehydrogenase activity
EXW27_16050	COG3343	RNA polymerase activity
EXW27_16055	COG0504	CTP synthase activity
EXW27_16060	COG4821	SIS domain
EXW27_16080	COG1494	fructose-1,6-bisphosphatase
EXW27_16090	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW27_16100	COG1435	thymidine kinase activity
EXW27_16105	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW27_16110	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW27_16125	COG0009	L-threonylcarbamoyladenylate synthase
EXW27_16130	COG1971	Probably functions as a manganese efflux pump
EXW27_16145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW27_16150	COG2259	Doxx family
EXW27_16155	COG2190	(PTS) system
EXW27_16165	COG0698	ribose 5-phosphate isomerase
EXW27_16175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW27_16200	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW27_16210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW27_16215	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW27_16220	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW27_16225	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW27_16230	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW27_16235	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW27_16250	COG5001	Diguanylate cyclase
EXW27_16250	COG3300	MHYT domain
EXW27_16255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW27_16260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW27_16265	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW27_16270	COG0649	NAD binding
EXW27_16275	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW27_16285	COG0839	Belongs to the complex I subunit 6 family
EXW27_16290	COG0713	ATP synthesis coupled electron transport
EXW27_16295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW27_16300	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW27_16305	COG1007	ATP synthesis coupled electron transport
EXW27_16310	COG4836	Membrane
EXW27_16325	COG2385	sporulation resulting in formation of a cellular spore
EXW27_16330	COG3279	Response regulator of the LytR AlgR family
EXW27_16345	COG0739	heme binding
EXW27_16355	COG1609	Transcriptional regulator
EXW27_16375	COG0489	protein tyrosine kinase activity
EXW27_16380	COG3944	biosynthesis protein
EXW27_16385	COG0489	protein tyrosine kinase activity
EXW27_16390	COG4464	protein tyrosine phosphatase activity
EXW27_16395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW27_16420	COG1215	transferase activity, transferring glycosyl groups
EXW27_16425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW27_16430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW27_16435	COG1316	TRANSCRIPTIONal
EXW27_16445	COG0745	RESPONSE REGULATOR receiver
EXW27_16450	COG3850	Histidine kinase
EXW27_16450	COG5002	protein histidine kinase activity
EXW27_16475	COG1136	(ABC) transporter
EXW27_16480	COG0577	efflux transmembrane transporter activity
EXW27_16520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW27_16525	COG4715	Zinc finger, swim domain protein
EXW27_16550	COG1388	LysM domain
EXW27_16550	COG3584	3D domain protein
EXW27_16560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW27_16565	COG1215	transferase activity, transferring glycosyl groups
EXW27_16575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW27_16580	COG1388	LysM domain
EXW27_16580	COG0791	NLP P60 protein
EXW27_16590	COG1368	sulfuric ester hydrolase activity
EXW27_16600	COG2389	metal-binding protein
EXW27_16610	COG1620	l-lactate permease
EXW27_16620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW27_16625	COG1294	oxidase, subunit
EXW27_16630	COG1271	oxidase subunit
EXW27_16635	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW27_16640	COG0583	DNA-binding transcription factor activity
EXW27_16645	COG1511	domain protein
EXW27_16665	COG1301	dicarboxylic acid transport
EXW27_16670	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW27_16680	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW27_16705	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW27_16710	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW27_16715	COG1486	melibiose metabolic process
EXW27_16735	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW27_16735	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW27_16745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW27_16750	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW27_16755	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW27_16760	COG1316	TRANSCRIPTIONal
EXW27_16765	COG1739	Uncharacterized protein family UPF0029
EXW27_16770	COG1307	EDD domain protein, DegV family
EXW27_16775	COG1733	regulation of RNA biosynthetic process
EXW27_16780	COG0791	NLP P60 protein
EXW27_16780	COG1388	LysM domain
EXW27_16785	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW27_16790	COG1040	competence protein
EXW27_16795	COG1278	Cold shock
EXW27_16830	COG1131	(ABC) transporter
EXW27_16865	COG2884	Cell division ATP-binding protein ftsE
EXW27_16870	COG2177	Part of the ABC transporter FtsEX involved in
EXW27_16875	COG0793	Belongs to the peptidase S41A family
EXW27_16875	COG3409	Peptidoglycan-binding domain 1 protein
EXW27_16880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW27_16885	COG1132	(ABC) transporter
EXW27_16895	COG0488	(ABC) transporter
EXW27_16900	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW27_16905	COG0789	Transcriptional regulator
EXW27_16910	COG0583	DNA-binding transcription factor activity
EXW27_16945	COG0789	Transcriptional regulator
EXW27_16965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW27_16970	COG1950	PFAM Membrane protein of
EXW27_16975	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW27_16980	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW27_16985	COG0546	phosphoglycolate phosphatase activity
EXW27_16990	COG0110	maltose O-acetyltransferase activity
EXW27_16995	COG0457	Tetratricopeptide repeat
EXW27_17000	COG0492	ferredoxin-NADP+ reductase activity
EXW27_17010	COG1051	belongs to the nudix hydrolase family
EXW27_17015	COG1660	Displays ATPase and GTPase activities
EXW27_17020	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW27_17025	COG1481	regulation of sporulation
EXW27_17030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW27_17040	COG2323	membrane
EXW27_17055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW27_17090	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW27_17105	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW27_17110	COG0126	phosphoglycerate kinase activity
EXW27_17115	COG0149	triose-phosphate isomerase activity
EXW27_17125	COG0148	phosphopyruvate hydratase activity
EXW27_17140	COG1346	cytolysis
EXW27_17145	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW27_17150	COG1647	Serine aminopeptidase, S33
EXW27_17155	COG0557	exoribonuclease II activity
EXW27_17165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW27_17185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW27_17210	COG2233	PERMEase
EXW27_17215	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW27_17220	COG0288	reversible hydration of carbon dioxide
EXW27_17225	COG1522	sequence-specific DNA binding
EXW27_17235	COG1522	sequence-specific DNA binding
EXW27_17240	COG1335	isochorismatase
EXW27_17245	COG4224	UPF0291 protein
EXW27_17250	COG0778	Nitroreductase
EXW27_17255	COG1733	regulation of RNA biosynthetic process
EXW27_17265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW27_17270	COG0488	(ABC) transporter
EXW27_17300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW27_17310	COG3290	protein histidine kinase activity
EXW27_17310	COG0840	transmembrane signaling receptor activity
EXW27_17330	COG1252	NADH dehydrogenase
EXW27_17340	COG1733	regulation of RNA biosynthetic process
EXW27_17345	COG2814	Major facilitator Superfamily
EXW27_17350	COG0656	L-ascorbic acid biosynthetic process
EXW27_17360	COG2910	NAD(P)H-binding
EXW27_17365	COG1115	amino acid carrier protein
EXW27_17370	COG1115	amino acid carrier protein
EXW27_17375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW27_17380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW27_17390	COG1528	Iron-storage protein
EXW27_17400	COG1611	Belongs to the LOG family
EXW27_17405	COG2318	DinB family
EXW27_17415	COG0783	Belongs to the Dps family
EXW27_17420	COG1115	amino acid carrier protein
EXW27_17425	COG0490	domain, Protein
EXW27_17430	COG0475	glutathione-regulated potassium exporter activity
EXW27_17435	COG0586	Pfam SNARE associated Golgi protein
EXW27_17450	COG1741	Belongs to the pirin family
EXW27_17455	COG3227	Zinc metalloprotease (Elastase)
EXW27_17460	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW27_17465	COG0840	transmembrane signaling receptor activity
EXW27_17470	COG0840	transmembrane signaling receptor activity
EXW27_17480	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW27_17490	COG5002	protein histidine kinase activity
EXW27_17495	COG0745	RESPONSE REGULATOR receiver
EXW27_17500	COG1376	ErfK ybiS ycfS ynhG family protein
EXW27_17510	COG0586	Pfam SNARE associated Golgi protein
EXW27_17545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW27_17570	COG0531	amino acid
EXW27_17575	COG2814	Major facilitator Superfamily
EXW27_17590	COG0840	transmembrane signaling receptor activity
EXW27_17595	COG0011	TIGRFAM Protein of
EXW27_17605	COG0506	proline dehydrogenase activity
EXW27_17610	COG1686	Belongs to the peptidase S11 family
EXW27_17620	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW27_17620	COG1024	Enoyl-CoA hydratase
EXW27_17625	COG0183	Belongs to the thiolase family
EXW27_17630	COG1960	acyl-CoA dehydrogenase activity
EXW27_17645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW27_17685	COG1393	Belongs to the ArsC family
EXW27_17690	COG0509	glycine decarboxylation via glycine cleavage system
EXW27_17695	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW27_17700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW27_17710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW27_17715	COG2011	ABC-type metal ion transport system permease component
EXW27_17720	COG1464	Belongs to the NlpA lipoprotein family
EXW27_17725	COG1464	Belongs to the NlpA lipoprotein family
EXW27_17730	COG0396	ATPase activity
EXW27_17735	COG0719	Fe-S assembly protein
EXW27_17740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW27_17745	COG0822	iron-sulfur transferase activity
EXW27_17750	COG0719	Fe-S assembly protein
EXW27_17760	COG1695	Transcriptional regulator
EXW27_17765	COG0737	Belongs to the 5'-nucleotidase family
EXW27_17770	COG3377	Domain of unknown function (DUF1805)
EXW27_17780	COG0739	heme binding
EXW27_17785	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW27_17805	COG4377	Putative membrane peptidase family (DUF2324)
EXW27_17810	COG0789	Transcriptional regulator
EXW27_17820	COG4470	Protein conserved in bacteria
EXW27_17835	COG1494	fructose-1,6-bisphosphatase
EXW27_17840	COG2445	Protein of unknown function DUF86
EXW27_17850	COG0647	UMP catabolic process
EXW27_17860	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW27_17865	COG1136	(ABC) transporter
EXW27_17865	COG0577	efflux transmembrane transporter activity
EXW27_17880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW27_17885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW27_17895	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW27_17900	COG4837	Protein of unknown function (DUF1462)
EXW27_17935	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW27_17940	COG0390	transport system, permease component
EXW27_17950	COG1252	NADH dehydrogenase
EXW27_17955	COG4844	belongs to the
EXW27_17960	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW27_17965	COG0316	Belongs to the HesB IscA family
EXW27_17990	COG1683	Conserved Protein
EXW27_18005	COG3708	Transcriptional regulator
EXW27_18010	COG0492	ferredoxin-NADP+ reductase activity
EXW27_18015	COG1252	NADH dehydrogenase
EXW27_18030	COG3584	3D domain protein
EXW27_18035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW27_18045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW27_18050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW27_18060	COG1268	BioY protein
EXW27_18070	COG2050	protein possibly involved in aromatic compounds catabolism
EXW27_18090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW27_18095	COG5018	Exonuclease
EXW27_18110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW27_18120	COG2267	carboxylic ester hydrolase activity
EXW27_18125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW27_18130	COG1522	sequence-specific DNA binding
EXW27_18135	COG0436	Aminotransferase
EXW27_18140	COG1098	S1 RNA binding domain
EXW27_18145	COG2155	Conserved Protein
EXW27_18155	COG0166	Belongs to the GPI family
EXW27_18165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW27_18170	COG1285	pathogenesis
EXW27_18330	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW27_18335	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW27_18340	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW27_18350	COG0058	SHG alpha-glucan phosphorylase activity
EXW27_18360	COG0789	Transcriptional regulator
EXW27_18370	COG1278	Cold shock
EXW27_18375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW27_18380	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW27_18385	COG1169	isochorismate synthase
EXW27_18390	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW27_18400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW27_18405	COG0318	PFAM AMP-dependent synthetase and ligase
EXW27_18410	COG4948	Mandelate Racemase Muconate Lactonizing
EXW27_18435	COG3964	amidohydrolase
EXW27_18455	COG2188	Transcriptional regulator
EXW27_18470	COG0577	efflux transmembrane transporter activity
EXW27_18475	COG1136	(ABC) transporter
EXW27_18480	COG0577	efflux transmembrane transporter activity
EXW27_18485	COG0577	efflux transmembrane transporter activity
EXW27_18490	COG2205	protein histidine kinase activity
EXW27_18495	COG0745	RESPONSE REGULATOR receiver
EXW27_18500	COG0640	Transcriptional regulator
EXW27_18505	COG5658	integral membrane protein
EXW27_18510	COG1131	(ABC) transporter
EXW27_18520	COG3708	Transcriptional regulator
EXW27_18520	COG2207	Transcriptional regulator
EXW27_18525	COG1136	(ABC) transporter
EXW27_18530	COG0577	efflux transmembrane transporter activity
EXW27_18545	COG0586	Pfam SNARE associated Golgi protein
EXW27_18555	COG5002	protein histidine kinase activity
EXW27_18585	COG1136	(ABC) transporter
EXW27_18600	COG1597	lipid kinase activity
EXW27_18605	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW27_18630	COG0745	RESPONSE REGULATOR receiver
EXW27_18635	COG5002	protein histidine kinase activity
EXW27_18640	COG3859	Proton-coupled thiamine transporter YuaJ
EXW27_18665	COG1842	Phage shock protein A
EXW27_18685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW27_18705	COG1294	oxidase, subunit
EXW27_18710	COG1271	oxidase subunit
EXW27_18715	COG0288	reversible hydration of carbon dioxide
EXW27_18725	COG1854	S-ribosylhomocysteine lyase activity
EXW27_18730	COG0789	Transcriptional regulator
EXW27_18745	COG2211	Major facilitator Superfamily
EXW27_18755	COG2076	Multidrug Resistance protein
EXW27_18760	COG2076	Multidrug Resistance protein
EXW27_18800	COG0494	nUDIX hydrolase
EXW27_18825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW27_18830	COG1116	anion transmembrane transporter activity
EXW27_18835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW27_18850	COG4895	conserved protein (DUF2196)
EXW27_18860	COG1368	sulfuric ester hydrolase activity
EXW27_18870	COG2267	carboxylic ester hydrolase activity
EXW27_18875	COG0753	catalase activity
EXW27_18880	COG3852	Histidine kinase
EXW27_18885	COG5002	protein histidine kinase activity
EXW27_18920	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW27_18925	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW27_18945	COG0746	molybdenum cofactor guanylyltransferase activity
EXW27_18960	COG0438	transferase activity, transferring glycosyl groups
EXW27_18965	COG0671	phosphoesterase, PA-phosphatase related
EXW27_18970	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW27_18975	COG2267	carboxylic ester hydrolase activity
EXW27_18995	COG1794	racemase activity, acting on amino acids and derivatives
EXW27_19005	COG1131	(ABC) transporter
EXW27_19015	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW27_19020	COG1242	4 iron, 4 sulfur cluster binding
EXW27_19035	COG1136	(ABC) transporter
EXW27_19050	COG0582	viral genome integration into host DNA
EXW27_19055	COG0490	domain, Protein
EXW27_19060	COG0475	glutathione-regulated potassium exporter activity
EXW27_19065	COG2814	Major facilitator Superfamily
EXW27_19070	COG0495	leucyl-tRNA aminoacylation
EXW27_19110	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW27_19120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW27_19145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW27_19150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW27_19155	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW27_19160	COG0303	'Molybdopterin
EXW27_19165	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW27_19170	COG0314	molybdopterin synthase activity
EXW27_19195	COG1329	Transcriptional regulator
EXW27_19215	COG3832	glyoxalase III activity
EXW27_19225	COG2814	Major facilitator Superfamily
EXW27_19230	COG2081	HI0933 family
EXW27_19235	COG2244	polysaccharide biosynthetic process
EXW27_19240	COG1187	pseudouridine synthase activity
EXW27_19245	COG1349	DNA-binding transcription factor activity
EXW27_19250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW27_19260	COG1523	belongs to the glycosyl hydrolase 13 family
EXW27_19265	COG0510	thiamine kinase activity
EXW27_19275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW27_19280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW27_19290	COG1363	Peptidase, m42
EXW27_19295	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW27_19300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW27_19305	COG4848	Belongs to the UPF0354 family
EXW27_19310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW27_19325	COG1674	ftsk spoiiie
EXW27_19335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW27_19340	COG0789	Transcriptional regulator
EXW27_19370	COG2309	aminopeptidase activity
EXW27_19380	COG3118	belongs to the thioredoxin family
EXW27_19385	COG4851	CamS sex pheromone cAM373 precursor
EXW27_19390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW27_19390	COG1605	Chorismate mutase
EXW27_19400	COG1609	Transcriptional regulator
EXW27_19420	COG1970	mechanosensitive ion channel activity
EXW27_19430	COG0666	response to abiotic stimulus
EXW27_19435	COG5002	protein histidine kinase activity
EXW27_19440	COG0745	RESPONSE REGULATOR receiver
EXW27_19450	COG2267	carboxylic ester hydrolase activity
EXW27_19455	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW27_19460	COG0517	IMP dehydrogenase activity
EXW27_19465	COG0454	-acetyltransferase
EXW27_19470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW27_19475	COG0456	acetyltransferase
EXW27_19480	COG0110	maltose O-acetyltransferase activity
EXW27_19490	COG1595	DNA-templated transcription, initiation
EXW27_19515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW27_19520	COG0626	cystathionine gamma-synthase activity
EXW27_19525	COG1956	GAF domain-containing protein
EXW27_19530	COG1309	transcriptional regulator
EXW27_19545	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW27_19550	COG1104	cysteine desulfurase activity
EXW27_19565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW27_19575	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW27_19590	COG3874	Sporulation protein YtfJ
EXW27_19595	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW27_19600	COG0827	DNA restriction-modification system
EXW27_19605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW27_19625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW27_19640	COG0137	argininosuccinate synthase activity
EXW27_19645	COG0165	Argininosuccinate lyase
EXW27_19665	COG0589	response to stress
EXW27_19670	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_19685	COG1476	TRANSCRIPTIONal
EXW27_19695	COG0662	Cupin 2, conserved barrel domain protein
EXW27_19730	COG0006	proline dipeptidase activity
EXW27_19735	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW27_19740	COG4109	DRTGG domain
EXW27_19760	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW27_19775	COG0587	DNA-directed DNA polymerase activity
EXW27_19780	COG0281	malic enzyme
EXW27_19785	COG1725	Transcriptional regulator
EXW27_19790	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW27_19800	COG0205	6-phosphofructokinase activity
EXW27_19810	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW27_19815	COG0628	permease
EXW27_19830	COG0372	Belongs to the citrate synthase family
EXW27_19835	COG0538	isocitrate dehydrogenase activity
EXW27_19840	COG0039	L-malate dehydrogenase activity
EXW27_19855	COG0745	RESPONSE REGULATOR receiver
EXW27_19860	COG5002	protein histidine kinase activity
EXW27_19865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW27_19865	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW27_19875	COG1971	Probably functions as a manganese efflux pump
EXW27_19880	COG0237	dephospho-CoA kinase activity
EXW27_19885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW27_19890	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW27_19895	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW27_19900	COG3611	Membrane attachment protein
EXW27_19905	COG1484	DNA-dependent DNA replication
EXW27_19915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW27_19930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW27_19940	COG1363	Peptidase, m42
EXW27_19950	COG1566	PFAM secretion protein HlyD family protein
EXW27_19955	COG2814	Major facilitator Superfamily
EXW27_19985	COG1418	mRNA catabolic process
EXW27_19995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW27_20000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW27_20025	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW27_20030	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW27_20035	COG1286	toxin biosynthetic process
EXW27_20040	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW27_20040	COG1796	DNA polymerase
EXW27_20045	COG1193	negative regulation of DNA recombination
EXW27_20050	COG1187	pseudouridine synthase activity
EXW27_20055	COG1114	Component of the transport system for branched-chain amino acids
EXW27_20060	COG5386	Cell surface protein
EXW27_20070	COG5386	Cell surface protein
EXW27_20085	COG1120	ATPase activity
EXW27_20090	COG4509	Sortase family
EXW27_20095	COG2329	Antibiotic biosynthesis monooxygenase
EXW27_20105	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW27_20110	COG4895	conserved protein (DUF2196)
EXW27_20115	COG0745	RESPONSE REGULATOR receiver
EXW27_20120	COG2205	protein histidine kinase activity
EXW27_20125	COG1131	(ABC) transporter
EXW27_20150	COG2318	DinB family
EXW27_20175	COG0318	PFAM AMP-dependent synthetase and ligase
EXW27_20180	COG1309	transcriptional regulator
EXW27_20185	COG1024	Enoyl-CoA hydratase
EXW27_20190	COG2086	electron transfer activity
EXW27_20195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW27_20200	COG3118	belongs to the thioredoxin family
EXW27_20205	COG0322	excinuclease ABC activity
EXW27_20210	COG1719	4-vinyl reductase, 4VR
EXW27_20215	COG2009	succinate dehydrogenase
EXW27_20220	COG1053	succinate dehydrogenase
EXW27_20225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW27_20230	COG0824	Thioesterase
EXW27_20235	COG1876	peptidase activity
EXW27_20245	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW27_20250	COG1360	Flagellar Motor Protein
EXW27_20255	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW27_20260	COG4152	abc transporter atp-binding protein
EXW27_20265	COG1668	transmembrane transport
EXW27_20270	COG1959	2 iron, 2 sulfur cluster binding
EXW27_20280	COG0697	spore germination
EXW27_20285	COG1396	sequence-specific DNA binding
EXW27_20290	COG1983	PspC domain protein
EXW27_20295	COG0402	S-adenosylhomocysteine deaminase activity
EXW27_20300	COG2233	PERMEase
EXW27_20305	COG2197	response regulator
EXW27_20310	COG0477	Major facilitator Superfamily
EXW27_20320	COG5401	PFAM Sporulation and spore germination
EXW27_20325	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW27_20335	COG0622	Phosphoesterase
EXW27_20365	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW27_20375	COG0470	DNA polymerase III
EXW27_20375	COG1067	ATP-dependent peptidase activity
EXW27_20385	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW27_20390	COG1764	response to oxidative stress
EXW27_20395	COG1846	Transcriptional regulator
EXW27_20400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW27_20405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW27_20410	COG0181	hydroxymethylbilane synthase activity
EXW27_20415	COG1587	Uroporphyrinogen-III synthase
EXW27_20420	COG0113	porphobilinogen synthase activity
EXW27_20425	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW27_20430	COG1388	LysM domain
EXW27_20445	COG0285	dihydrofolate synthase activity
EXW27_20460	COG0424	maF-like protein
EXW27_20465	COG2003	Belongs to the UPF0758 family
EXW27_20470	COG1077	Cell shape determining protein MreB Mrl
EXW27_20485	COG0850	regulation of cytokinetic process
EXW27_20490	COG2894	cell division
EXW27_20495	COG0739	heme binding
EXW27_20500	COG1994	Peptidase M50
EXW27_20505	COG1530	ribonuclease E activity
EXW27_20515	COG2868	ribosomal protein
EXW27_20525	COG3290	protein histidine kinase activity
EXW27_20530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW27_20535	COG0745	RESPONSE REGULATOR receiver
EXW27_20540	COG5002	protein histidine kinase activity
EXW27_20545	COG1136	(ABC) transporter
EXW27_20550	COG0577	efflux transmembrane transporter activity
EXW27_20555	COG0577	efflux transmembrane transporter activity
EXW27_20560	COG0077	Prephenate dehydratase
EXW27_20565	COG2258	MOSC domain
EXW27_20570	COG1827	regulation of RNA biosynthetic process
EXW27_20575	COG1104	cysteine desulfurase activity
EXW27_20580	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW27_20585	COG0157	Belongs to the NadC ModD family
EXW27_20590	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW27_20620	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW27_20625	COG0632	four-way junction helicase activity
EXW27_20630	COG2255	four-way junction helicase activity
EXW27_20640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW27_20645	COG0343	queuine tRNA-ribosyltransferase activity
EXW27_20650	COG1862	Preprotein translocase
EXW27_20660	COG2323	membrane
EXW27_20665	COG2244	polysaccharide biosynthetic process
EXW27_20675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW27_20675	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW27_20680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW27_20685	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW27_20685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW27_20690	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW27_20695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW27_20700	COG1490	D-aminoacyl-tRNA deacylase activity
EXW27_20710	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW27_20715	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW27_20725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW27_20730	COG1959	2 iron, 2 sulfur cluster binding
EXW27_20735	COG1104	cysteine desulfurase activity
EXW27_20740	COG0482	sulfurtransferase activity
EXW27_20750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW27_20770	COG0628	permease
EXW27_20780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW27_20785	COG4472	Bacterial protein of unknown function (DUF965)
EXW27_20790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW27_20800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW27_20805	COG4122	O-methyltransferase activity
EXW27_20810	COG0826	peptidase U32
EXW27_20815	COG0826	peptidase U32
EXW27_20820	COG0572	uridine kinase
EXW27_20825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW27_20830	COG0768	penicillin binding
EXW27_20845	COG2226	methyltransferase
EXW27_20850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW27_20855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW27_20860	COG0626	cystathionine gamma-synthase activity
EXW27_20865	COG1012	belongs to the aldehyde dehydrogenase family
EXW27_20865	COG1454	alcohol dehydrogenase
EXW27_20875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW27_20915	COG2259	Doxx family
EXW27_20920	COG2514	catechol 2,3-dioxygenase activity
EXW27_20925	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW27_20930	COG3186	Phenylalanine-4-hydroxylase
EXW27_20935	COG1404	Belongs to the peptidase S8 family
EXW27_20970	COG2267	carboxylic ester hydrolase activity
EXW27_20980	COG1785	Belongs to the alkaline phosphatase family
EXW27_20990	COG2357	RelA SpoT domain protein
EXW27_20995	COG1595	DNA-templated transcription, initiation
EXW27_21005	COG0688	phosphatidylethanolamine metabolic process
EXW27_21015	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW27_21020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW27_21025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW27_21030	COG1534	Rna-binding protein
EXW27_21035	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW27_21040	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW27_21045	COG0799	negative regulation of ribosome biogenesis
EXW27_21050	COG2226	methyltransferase
EXW27_21055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW27_21060	COG1596	polysaccharide export
EXW27_21060	COG1555	photosystem II stabilization
EXW27_21065	COG2131	deaminase
EXW27_21070	COG2333	competence protein COMEC
EXW27_21070	COG0658	competence protein
EXW27_21080	COG1466	dna polymerase III delta subunit
EXW27_21085	COG0268	Binds directly to 16S ribosomal RNA
EXW27_21090	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW27_21100	COG0481	GTPase activity
EXW27_21105	COG1733	regulation of RNA biosynthetic process
EXW27_21110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW27_21115	COG1420	regulation of RNA biosynthetic process
EXW27_21125	COG0443	Heat shock 70 kDa protein
EXW27_21130	COG0484	heat shock protein binding
EXW27_21140	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW27_21145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW27_21150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW27_21155	COG1610	YqeY-like protein
EXW27_21170	COG1702	phosphate starvation-inducible protein PhoH
EXW27_21175	COG1480	7TM receptor with intracellular HD hydrolase
EXW27_21180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW27_21185	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW27_21190	COG0295	cytidine deaminase activity
EXW27_21195	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW27_21205	COG1381	Involved in DNA repair and RecF pathway recombination
EXW27_21210	COG0517	IMP dehydrogenase activity
EXW27_21215	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW27_21225	COG0358	DNA primase activity
EXW27_21230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW27_21235	COG2010	Cytochrome c
EXW27_21240	COG2384	SAM-dependent methyltransferase
EXW27_21245	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW27_21250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW27_21265	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW27_21275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW27_21280	COG1121	(ABC) transporter
EXW27_21285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW27_21290	COG0735	belongs to the Fur family
EXW27_21295	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW27_21315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW27_21320	COG0477	Major facilitator Superfamily
EXW27_21325	COG0768	penicillin binding
EXW27_21330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW27_21335	COG0573	inorganic phosphate transmembrane transporter activity
EXW27_21340	COG0581	inorganic phosphate transmembrane transporter activity
EXW27_21350	COG0704	Plays a role in the regulation of phosphate uptake
EXW27_21355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW27_21360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW27_21365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW27_21370	COG4483	Protein conserved in bacteria
EXW27_21375	COG1940	carbohydrate kinase activity
EXW27_21385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW27_21405	COG0626	cystathionine gamma-synthase activity
EXW27_21410	COG0626	cystathionine gamma-synthase activity
EXW27_21415	COG0646	methionine synthase
EXW27_21415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW27_21420	COG1410	methionine synthase
EXW27_21420	COG0646	methionine synthase
EXW27_21475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW27_21480	COG1459	type II secretion system
EXW27_21490	COG4970	Tfp pilus assembly protein FimT
EXW27_21515	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW27_21545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW27_21550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW27_21555	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW27_21560	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW27_21575	COG1725	Transcriptional regulator
EXW27_21610	COG2076	Multidrug Resistance protein
EXW27_21615	COG2076	Multidrug Resistance protein
EXW27_21625	COG1609	Transcriptional regulator
EXW27_21635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW27_21670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW27_21680	COG3872	metal-dependent enzyme
EXW27_21690	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW27_21695	COG0006	proline dipeptidase activity
EXW27_21700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW27_21720	COG3854	ATPases associated with a variety of cellular activities
EXW27_21765	COG0511	ligase activity, forming carbon-carbon bonds
EXW27_21770	COG0439	Biotin carboxylase
EXW27_21775	COG1302	Protein conserved in bacteria
EXW27_21780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW27_21785	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW27_21790	COG1570	exodeoxyribonuclease VII activity
EXW27_21795	COG1722	exodeoxyribonuclease VII activity
EXW27_21800	COG0142	geranyltranstransferase activity
EXW27_21805	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW27_21810	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW27_21815	COG1438	arginine binding
EXW27_21820	COG0497	DNA recombination
EXW27_21825	COG0750	zinc metalloprotease
EXW27_21835	COG0745	RESPONSE REGULATOR receiver
EXW27_21845	COG3093	addiction module antidote protein HigA
EXW27_21850	COG0584	glycerophosphoryl diester phosphodiesterase
EXW27_21860	COG3290	protein histidine kinase activity
EXW27_21860	COG3829	transcription factor binding
EXW27_21870	COG0280	phosphate acetyltransferase
EXW27_21880	COG3426	butyrate kinase activity
EXW27_21885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW27_21890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW27_21895	COG0022	dehydrogenase e1 component
EXW27_21900	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW27_21910	COG0772	Belongs to the SEDS family
EXW27_21915	COG2323	membrane
EXW27_21920	COG2816	NAD+ diphosphatase activity
EXW27_21930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW27_21935	COG0765	amino acid transport
EXW27_21940	COG1126	abc transporter atp-binding protein
EXW27_21945	COG4129	membrane
EXW27_21950	COG1376	ErfK ybiS ycfS ynhG family protein
EXW27_21960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW27_21965	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW27_21990	COG1234	tRNA 3'-trailer cleavage
EXW27_22000	COG1760	l-serine dehydratase
EXW27_22005	COG1760	l-serine dehydratase
EXW27_22010	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW27_22015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW27_22020	COG0300	oxidoreductase activity
EXW27_22030	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW27_22065	COG1522	sequence-specific DNA binding
EXW27_22075	COG0737	Belongs to the 5'-nucleotidase family
EXW27_22080	COG1757	Na H antiporter
EXW27_22090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW27_22100	COG0156	8-amino-7-oxononanoate synthase activity
EXW27_22105	COG2226	methyltransferase
EXW27_22105	COG1073	alpha beta
EXW27_22110	COG4106	trans-aconitate 2-methyltransferase activity
EXW27_22115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW27_22130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW27_22130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW27_22135	COG0307	riboflavin synthase, alpha
EXW27_22140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW27_22140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW27_22155	COG1073	alpha beta
EXW27_22160	COG0456	acetyltransferase
EXW27_22165	COG1609	Transcriptional regulator
EXW27_22170	COG2056	Na+-H+ antiporter family
EXW27_22175	COG0596	Alpha beta hydrolase
EXW27_22185	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW27_22190	COG4085	toxin activity
EXW27_22190	COG0737	Belongs to the 5'-nucleotidase family
EXW27_22190	COG1525	nuclease
EXW27_22200	COG0456	acetyltransferase
EXW27_22200	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW27_22205	COG0656	L-ascorbic acid biosynthetic process
EXW27_22210	COG0667	Aldo Keto reductase
EXW27_22230	COG1300	Membrane
EXW27_22235	COG0735	belongs to the Fur family
EXW27_22245	COG4974	Belongs to the 'phage' integrase family
EXW27_22255	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW27_22270	COG0598	Magnesium transport protein CorA
EXW27_22285	COG1846	Transcriptional regulator
EXW27_22305	COG1131	(ABC) transporter
EXW27_22310	COG1725	Transcriptional regulator
EXW27_22315	COG1686	Belongs to the peptidase S11 family
EXW27_22355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW27_22370	COG0697	spore germination
EXW27_22375	COG0561	phosphatase activity
EXW27_22380	COG4086	secreted protein
EXW27_22385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW27_22395	COG1547	Domain of unknown function (DUF309)
EXW27_22405	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW27_22415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW27_22425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW27_22430	COG0363	glucosamine-6-phosphate deaminase activity
EXW27_22435	COG2188	Transcriptional regulator
EXW27_22445	COG3711	transcriptional antiterminator
EXW27_22450	COG1263	PTS System
EXW27_22450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW27_22450	COG2190	(PTS) system
EXW27_22475	COG0778	Nitroreductase
EXW27_22480	COG2199	diguanylate cyclase activity
EXW27_22490	COG2084	Dehydrogenase
EXW27_22505	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW27_22510	COG0235	Class ii aldolase
EXW27_22515	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW27_22520	COG1850	ribulose-bisphosphate carboxylase activity
EXW27_22525	COG0436	Aminotransferase
EXW27_22530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW27_22535	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW27_22540	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW27_22550	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_22555	COG1695	Transcriptional regulator
EXW27_22590	COG0183	Belongs to the thiolase family
EXW27_22635	COG3842	ATPase activity
EXW27_22640	COG0366	Alpha amylase catalytic
EXW27_22650	COG2182	Extracellular solute-binding protein
EXW27_22655	COG1175	transmembrane transport
EXW27_22660	COG3833	ABC-type maltose transport systems, permease component
EXW27_22665	COG1609	Transcriptional regulator
EXW27_22670	COG0436	Aminotransferase
EXW27_22680	COG2205	protein histidine kinase activity
EXW27_22690	COG3209	COG3209 Rhs family protein
EXW27_22700	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW27_22710	COG2814	Major facilitator Superfamily
EXW27_22755	COG1408	metallophosphoesterase
EXW27_22760	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_22765	COG2200	EAL domain
EXW27_22780	COG4703	Protein of unknown function (DUF1797)
EXW27_22790	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW27_22800	COG0517	IMP dehydrogenase activity
EXW27_22805	COG0583	DNA-binding transcription factor activity
EXW27_22810	COG2171	N-acyltransferase activity
EXW27_22815	COG1473	amidohydrolase
EXW27_22825	COG0569	domain protein
EXW27_22830	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW27_22835	COG5503	Protein of unknown function (DUF1447)
EXW27_22845	COG0561	phosphatase activity
EXW27_22860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW27_22865	COG0022	dehydrogenase e1 component
EXW27_22870	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW27_22915	COG1982	Orn Lys Arg decarboxylase major
EXW27_22920	COG4476	Belongs to the UPF0223 family
EXW27_22925	COG4493	Belongs to the UPF0637 family
EXW27_22935	COG0483	inositol monophosphate 1-phosphatase activity
EXW27_22945	COG1217	gtp-binding protein TYPA
EXW27_22960	COG4896	Protein conserved in bacteria
EXW27_22970	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW27_22975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW27_22980	COG4838	Belongs to the UPF0358 family
EXW27_22985	COG0772	Belongs to the SEDS family
EXW27_22995	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW27_23000	COG1612	heme a metabolic process
EXW27_23005	COG0109	protoheme IX farnesyltransferase activity
EXW27_23030	COG3336	cytochrome c oxidase
EXW27_23040	COG2340	Cysteine-rich secretory protein family
EXW27_23055	COG0406	alpha-ribazole phosphatase activity
EXW27_23060	COG3679	Belongs to the UPF0342 family
EXW27_23065	COG4471	UPF0298 protein
EXW27_23075	COG0742	ribosomal rna small subunit methyltransferase
EXW27_23085	COG3314	Sporulation integral membrane protein YlbJ
EXW27_23090	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW27_23095	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW27_23100	COG1323	Belongs to the UPF0348 family
EXW27_23105	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW27_23110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW27_23120	COG0454	-acetyltransferase
EXW27_23125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW27_23130	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW27_23135	COG0275	rRNA processing
EXW27_23145	COG0768	penicillin binding
EXW27_23150	COG0768	penicillin binding
EXW27_23155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW27_23160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW27_23165	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW27_23170	COG0772	Belongs to the SEDS family
EXW27_23185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW27_23190	COG0849	cell division
EXW27_23195	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW27_23205	COG1191	sigma factor activity
EXW27_23210	COG1191	sigma factor activity
EXW27_23215	COG1873	PFAM PRC-barrel domain
EXW27_23225	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW27_23230	COG1799	cell septum assembly
EXW27_23235	COG0762	integral membrane protein
EXW27_23240	COG2302	S4 RNA-binding domain
EXW27_23245	COG3599	regulation of cell shape
EXW27_23250	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW27_23260	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW27_23265	COG0564	pseudouridine synthase activity
EXW27_23270	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW27_23280	COG0540	Belongs to the ATCase OTCase family
EXW27_23285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW27_23295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW27_23300	COG0543	2 iron, 2 sulfur cluster binding
EXW27_23305	COG0167	dihydroorotate dehydrogenase activity
EXW27_23330	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW27_23350	COG0006	proline dipeptidase activity
EXW27_23360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW27_23365	COG1561	YicC-like family, N-terminal region
EXW27_23380	COG1758	RNA polymerase activity
EXW27_23385	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW27_23390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW27_23395	COG0242	peptide deformylase activity
EXW27_23400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW27_23405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW27_23405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW27_23410	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW27_23415	COG0631	protein serine/threonine phosphatase activity
EXW27_23420	COG0515	serine threonine protein kinase
EXW27_23420	COG2815	serine threonine protein kinase
EXW27_23430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW27_23435	COG1564	THIamine pyrophosphokinase
EXW27_23450	COG1302	Protein conserved in bacteria
EXW27_23455	COG1461	Dihydroxyacetone kinase
EXW27_23460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW27_23465	COG1349	DNA-binding transcription factor activity
EXW27_23465	COG2050	protein possibly involved in aromatic compounds catabolism
EXW27_23470	COG0416	fatty acid biosynthetic process
EXW27_23475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW27_23480	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_23485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW27_23490	COG0571	ribonuclease III activity
EXW27_23495	COG1196	nuclear chromosome segregation
EXW27_23500	COG0552	protein localization to endoplasmic reticulum
EXW27_23510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW27_23520	COG1837	Belongs to the UPF0109 family
EXW27_23525	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW27_23530	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW27_23535	COG0335	large ribosomal subunit rRNA binding
EXW27_23550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW27_23555	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW27_23560	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW27_23565	COG0758	DNA mediated transformation
EXW27_23570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW27_23575	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW27_23580	COG4974	Belongs to the 'phage' integrase family
EXW27_23585	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW27_23590	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW27_23595	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW27_23605	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW27_23610	COG0528	UMP kinase activity
EXW27_23615	COG0233	cytoplasmic translational termination
EXW27_23625	COG4589	Belongs to the CDS family
EXW27_23635	COG0750	zinc metalloprotease
EXW27_23640	COG0442	prolyl-tRNA aminoacylation
EXW27_23650	COG0779	Required for maturation of 30S ribosomal subunits
EXW27_23655	COG0195	Participates in both transcription termination and antitermination
EXW27_23660	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW27_23665	COG1358	cellular component organization or biogenesis
EXW27_23670	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW27_23675	COG1550	Protein conserved in bacteria
EXW27_23680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW27_23690	COG0196	riboflavin kinase activity
EXW27_23700	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW27_23705	COG0726	polysaccharide deacetylase
EXW27_23710	COG0612	Peptidase, M16
EXW27_23715	COG1873	PFAM PRC-barrel domain
EXW27_23720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW27_23750	COG1396	sequence-specific DNA binding
EXW27_23785	COG0305	Participates in initiation and elongation during chromosome replication
EXW27_23845	COG0582	viral genome integration into host DNA
EXW27_23980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW27_23985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW27_23990	COG0527	aspartate kinase activity
EXW27_24000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW27_24005	COG0740	serine-type endopeptidase activity
EXW27_24015	COG1674	ftsk spoiiie
EXW27_24025	COG2188	Transcriptional regulator
EXW27_24030	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW27_24035	COG3845	ABC transporter
EXW27_24040	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW27_24045	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW27_24050	COG0612	Peptidase, M16
EXW27_24055	COG0612	Peptidase, M16
EXW27_24060	COG0300	oxidoreductase activity
EXW27_24075	COG1426	Protein conserved in bacteria
EXW27_24080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW27_24085	COG1058	Belongs to the CinA family
EXW27_24085	COG1546	Belongs to the CinA family
EXW27_24090	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW27_24095	COG1418	mRNA catabolic process
EXW27_24100	COG1692	metallophosphoesterase
EXW27_24105	COG2359	stage V sporulation protein S
EXW27_24115	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW27_24115	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW27_24120	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW27_24125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW27_24130	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW27_24140	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW27_24145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW27_24150	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW27_24160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW27_24170	COG3773	Cell wall hydrolase
EXW27_24180	COG2723	6-phospho-beta-galactosidase activity
EXW27_24185	COG2188	Transcriptional regulator
EXW27_24200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW27_24205	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW27_24205	COG0596	Alpha beta hydrolase
EXW27_24210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW27_24220	COG1346	cytolysis
EXW27_24260	COG3300	MHYT domain
EXW27_24260	COG5001	Diguanylate cyclase
EXW27_24265	COG0346	lactoylglutathione lyase activity
EXW27_24275	COG2364	Membrane
EXW27_24280	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW27_24285	COG2706	6-phosphogluconolactonase activity
EXW27_24290	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW27_24295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW27_24300	COG2169	Transcriptional regulator
EXW27_24305	COG0708	Exodeoxyribonuclease III
EXW27_24310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW27_24315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW27_24320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW27_24325	COG1120	ATPase activity
EXW27_24330	COG2819	hydrolase of the alpha beta superfamily
EXW27_24335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW27_24340	COG4566	intracellular signal transduction
EXW27_24370	COG1937	Protein conserved in bacteria
EXW27_24375	COG2608	mercury ion transmembrane transporter activity
EXW27_24380	COG2217	Heavy metal translocating P-type atpase
EXW27_24395	COG2116	formate transmembrane transporter activity
EXW27_24400	COG1408	metallophosphoesterase
EXW27_24405	COG1473	amidohydrolase
EXW27_24420	COG1113	amino acid transport
EXW27_24430	COG2322	membrane
EXW27_24435	COG1979	alcohol dehydrogenase
EXW27_24440	COG1349	DNA-binding transcription factor activity
EXW27_24445	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW27_24450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW27_24450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW27_24450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW27_24455	COG3584	3D domain protein
EXW27_24455	COG1388	LysM domain
EXW27_24465	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW27_24495	COG0464	growth
EXW27_24500	COG2860	membrane
EXW27_24505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW27_24510	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW27_24515	COG0789	Transcriptional regulator
EXW27_24520	COG0174	glutamine synthetase
EXW27_24525	COG3944	biosynthesis protein
EXW27_24530	COG0489	protein tyrosine kinase activity
EXW27_24535	COG1086	Polysaccharide biosynthesis protein
EXW27_24540	COG0438	transferase activity, transferring glycosyl groups
EXW27_24545	COG0438	transferase activity, transferring glycosyl groups
EXW27_24550	COG0463	Glycosyl transferase, family 2
EXW27_24550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW27_24560	COG0438	transferase activity, transferring glycosyl groups
EXW27_24585	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW27_24585	COG3420	alginic acid biosynthetic process
EXW27_24590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW27_24595	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW27_24605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW27_24640	COG1132	(ABC) transporter
EXW27_24645	COG1695	Transcriptional regulator
EXW27_24660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW27_24665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW27_24675	COG0737	Belongs to the 5'-nucleotidase family
EXW27_24680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW27_24690	COG3639	organic phosphonate transmembrane transporter activity
EXW27_24710	COG3763	UPF0154 protein
EXW27_24715	COG1132	(ABC) transporter
EXW27_24720	COG1132	(ABC) transporter
EXW27_24740	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW27_24740	COG3409	Peptidoglycan-binding domain 1 protein
EXW27_24750	COG0730	response to heat
EXW27_24765	COG1346	cytolysis
EXW27_24775	COG0583	DNA-binding transcription factor activity
EXW27_24785	COG1131	(ABC) transporter
EXW27_24790	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW27_24795	COG1473	amidohydrolase
EXW27_24810	COG0785	Cytochrome C biogenesis protein
EXW27_24815	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW27_24845	COG2226	methyltransferase
EXW27_24855	COG2986	histidine ammonia-lyase
EXW27_24860	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW27_24870	COG0010	Belongs to the arginase family
EXW27_24875	COG1329	Transcriptional regulator
EXW27_24885	COG1902	pentaerythritol trinitrate reductase activity
EXW27_24890	COG0069	glutamate synthase activity
EXW27_24895	COG0346	lactoylglutathione lyase activity
EXW27_24900	COG0400	carboxylic ester hydrolase activity
EXW27_24910	COG5002	protein histidine kinase activity
EXW27_24925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW27_24965	COG0830	nickel cation binding
EXW27_24985	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EXW27_25005	COG1396	sequence-specific DNA binding
EXW27_25010	COG0318	PFAM AMP-dependent synthetase and ligase
EXW27_25015	COG1268	BioY protein
EXW27_25020	COG0318	PFAM AMP-dependent synthetase and ligase
EXW27_25025	COG0183	Belongs to the thiolase family
EXW27_25040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW27_25050	COG2211	Major facilitator Superfamily
EXW27_25080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW27_25085	COG1132	(ABC) transporter
EXW27_25105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW27_25130	COG0824	Thioesterase
EXW27_25135	COG4841	protein insertion into membrane
EXW27_25145	COG1328	CTP reductase activity
EXW27_25155	COG0745	RESPONSE REGULATOR receiver
EXW27_25160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW27_25165	COG1832	CoA-binding protein
EXW27_25170	COG0187	DNA topoisomerase II activity
EXW27_25175	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW27_25180	COG0673	inositol 2-dehydrogenase activity
EXW27_25200	COG1131	(ABC) transporter
EXW27_25220	COG1316	TRANSCRIPTIONal
EXW27_25225	COG4166	transmembrane transport
EXW27_25230	COG4166	transmembrane transport
EXW27_25235	COG4166	transmembrane transport
EXW27_25240	COG2226	methyltransferase
EXW27_25275	COG0531	amino acid
EXW27_25280	COG3326	Membrane
EXW27_25285	COG2962	Rard protein
EXW27_25290	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW27_25295	COG1657	PFAM Prenyltransferase squalene oxidase
EXW27_25305	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_25310	COG1012	belongs to the aldehyde dehydrogenase family
EXW27_25320	COG4145	pantothenate transmembrane transporter activity
EXW27_25335	COG0165	Argininosuccinate lyase
EXW27_25345	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_25365	COG0494	nUDIX hydrolase
EXW27_25375	COG0716	FMN binding
EXW27_25385	COG1278	Cold shock
EXW27_25410	COG2720	vancomycin resistance protein
EXW27_25415	COG0765	amino acid transport
EXW27_25420	COG1126	abc transporter atp-binding protein
EXW27_25425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW27_25430	COG2514	catechol 2,3-dioxygenase activity
EXW27_25445	COG1285	pathogenesis
EXW27_25465	COG0277	FAD linked oxidase domain protein
EXW27_25475	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW27_25480	COG2808	Putative FMN-binding domain
EXW27_25485	COG0457	Tetratricopeptide repeat
EXW27_25495	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW27_25500	COG0604	alcohol dehydrogenase
EXW27_25505	COG0640	Transcriptional regulator
EXW27_25510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW27_25550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW27_25565	COG3781	membrane
EXW27_25585	COG2957	Belongs to the agmatine deiminase family
EXW27_25590	COG1164	Oligoendopeptidase f
EXW27_25595	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW27_25605	COG1193	negative regulation of DNA recombination
EXW27_25630	COG0583	DNA-binding transcription factor activity
EXW27_25650	COG3739	integral membrane protein
EXW27_25655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW27_25660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW27_25665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW27_25685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW27_25690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW27_25705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW27_25710	COG1012	belongs to the aldehyde dehydrogenase family
EXW27_25715	COG0534	Mate efflux family protein
EXW27_25725	COG1012	belongs to the aldehyde dehydrogenase family
EXW27_25730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW27_25740	COG2814	Major facilitator Superfamily
EXW27_25750	COG1113	amino acid transport
EXW27_25755	COG0604	alcohol dehydrogenase
EXW27_25760	COG1695	Transcriptional regulator
EXW27_25805	COG2072	flavoprotein involved in K transport
EXW27_25815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW27_25845	COG1151	hydroxylamine reductase activity
EXW27_25875	COG0814	amino acid
EXW27_25925	COG5002	protein histidine kinase activity
EXW27_25950	COG0741	lytic transglycosylase activity
EXW27_25990	COG1876	peptidase activity
EXW27_26005	COG1191	sigma factor activity
EXW27_26020	COG1733	regulation of RNA biosynthetic process
EXW27_26025	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW27_26030	COG0318	PFAM AMP-dependent synthetase and ligase
EXW27_26040	COG0384	phenazine biosynthesis protein PhzF
EXW27_26055	COG0494	nUDIX hydrolase
EXW27_26070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW27_26080	COG1393	Belongs to the ArsC family
EXW27_26100	COG0814	amino acid
EXW27_26115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW27_26120	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW27_26130	COG1070	Carbohydrate kinase
EXW27_26135	COG2706	6-phosphogluconolactonase activity
EXW27_26140	COG3813	Protein conserved in bacteria
EXW27_26145	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW27_26150	COG0697	spore germination
EXW27_26175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW27_26185	COG0789	Transcriptional regulator
EXW27_26190	COG1253	flavin adenine dinucleotide binding
EXW27_26200	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW27_26230	COG2261	transglycosylase associated protein
EXW27_26235	COG0628	permease
EXW27_26250	COG0110	maltose O-acetyltransferase activity
EXW27_26255	COG0738	Major facilitator superfamily
EXW27_26260	COG1940	carbohydrate kinase activity
EXW27_26265	COG0346	lactoylglutathione lyase activity
EXW27_26290	COG2365	Tyrosine phosphatase family
EXW27_26295	COG1011	Hydrolase
EXW27_26310	COG1595	DNA-templated transcription, initiation
EXW27_26340	COG1131	(ABC) transporter
EXW27_26350	COG1028	Short-chain dehydrogenase reductase Sdr
EXW27_26370	COG1733	regulation of RNA biosynthetic process
EXW27_26375	COG0778	Nitroreductase
EXW27_26380	COG1785	Belongs to the alkaline phosphatase family
EXW27_26400	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW27_26425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW27_26430	COG2356	endonuclease I
EXW27_26435	COG1288	antiporter activity
EXW27_26440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW27_26490	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW27_26500	COG2031	fatty acid transporter
EXW27_26515	COG4187	Peptidase family M20/M25/M40
EXW27_26630	COG1131	(ABC) transporter
EXW27_26645	COG1136	(ABC) transporter
EXW27_26660	COG5002	protein histidine kinase activity
EXW27_26715	COG1329	Transcriptional regulator
EXW27_26745	COG0640	Transcriptional regulator
EXW27_26765	COG2814	Major facilitator Superfamily
EXW27_26770	COG1846	Transcriptional regulator
EXW27_26785	COG0477	Major facilitator Superfamily
EXW27_26910	COG2814	Major facilitator Superfamily
EXW27_26915	COG1309	transcriptional regulator
EXW27_26955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW27_26975	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW27_26990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW27_27000	COG5002	protein histidine kinase activity
EXW27_27000	COG3850	Histidine kinase
EXW27_27020	COG0577	efflux transmembrane transporter activity
EXW27_27025	COG1136	(ABC) transporter
EXW27_27040	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW27_27050	COG1522	sequence-specific DNA binding
EXW27_27075	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW27_27090	COG2814	Major facilitator Superfamily
EXW27_27130	COG4977	sequence-specific DNA binding
EXW27_27155	COG5002	protein histidine kinase activity
EXW27_27165	COG0745	RESPONSE REGULATOR receiver
EXW27_27170	COG5002	protein histidine kinase activity
EXW27_27180	COG1760	l-serine dehydratase
EXW27_27185	COG1760	l-serine dehydratase
EXW27_27190	COG0814	amino acid
EXW27_27200	COG1073	alpha beta
EXW27_27235	COG5002	protein histidine kinase activity
EXW27_27235	COG3850	Histidine kinase
EXW27_27240	COG0745	RESPONSE REGULATOR receiver
EXW27_27270	COG0346	lactoylglutathione lyase activity
EXW27_27290	COG1522	sequence-specific DNA binding
EXW27_27300	COG0640	Transcriptional regulator
EXW27_27305	COG0346	lactoylglutathione lyase activity
EXW27_27310	COG0798	PFAM Bile acid sodium symporter
EXW27_27350	COG0745	RESPONSE REGULATOR receiver
EXW27_27355	COG5002	protein histidine kinase activity
EXW27_27390	COG3848	Pyruvate phosphate dikinase
EXW27_27390	COG0574	Belongs to the PEP-utilizing enzyme family
EXW27_27425	COG1136	(ABC) transporter
EXW27_27430	COG0577	efflux transmembrane transporter activity
EXW27_27435	COG0577	efflux transmembrane transporter activity
EXW27_27440	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW27_27460	COG3314	Sporulation integral membrane protein YlbJ
EXW27_27470	COG0640	Transcriptional regulator
EXW27_27495	COG1960	acyl-CoA dehydrogenase activity
EXW27_27505	COG3142	Participates in the control of copper homeostasis
EXW27_27515	COG1414	Transcriptional regulator
EXW27_27520	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW27_27525	COG1984	allophanate hydrolase subunit 2
EXW27_27530	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW27_27545	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW27_27550	COG3104	oligopeptide transport
EXW27_27565	COG0768	penicillin binding
EXW27_27600	COG4335	DNA alkylation repair
EXW27_27610	COG0833	amino acid
EXW27_27620	COG0730	response to heat
EXW27_27645	COG0456	acetyltransferase
EXW27_27645	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW27_27655	COG0596	Alpha beta hydrolase
EXW27_27660	COG0745	RESPONSE REGULATOR receiver
EXW27_27665	COG0642	Histidine kinase
EXW27_27675	COG0697	spore germination
EXW27_27680	COG0814	amino acid
EXW27_27710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW27_27715	COG0697	spore germination
EXW27_27730	COG0456	acetyltransferase
EXW27_27735	COG2207	Transcriptional regulator
EXW27_27765	COG0582	viral genome integration into host DNA
EXW27_27775	COG1396	sequence-specific DNA binding
EXW27_27785	COG3645	SOS response
EXW27_27785	COG3646	Phage regulatory protein
EXW27_27805	COG1484	DNA-dependent DNA replication
EXW27_27815	COG2002	toxin-antitoxin pair type II binding
EXW27_27850	COG0270	DNA (cytosine-5-)-methyltransferase activity
EXW27_27870	COG0582	viral genome integration into host DNA
EXW27_27925	COG1192	Involved in chromosome partitioning
EXW27_28085	COG5484	DNA packaging
EXW27_28095	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW27_28140	COG2002	toxin-antitoxin pair type II binding
EXW27_28250	COG1396	sequence-specific DNA binding
EXW27_28370	COG0592	DNA-directed DNA polymerase activity
EXW27_28375	COG4712	double-strand break repair protein
EXW27_28530	COG4962	Type ii secretion system protein e
EXW27_28700	COG2311	Membrane
EXW27_28715	COG0519	Catalyzes the synthesis of GMP from XMP
EXW27_28795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW27_28830	COG0582	viral genome integration into host DNA
EXW27_28845	COG2378	regulation of single-species biofilm formation
EXW27_28850	COG2318	DinB family
EXW27_28860	COG0789	Transcriptional regulator
EXW27_28875	COG0840	transmembrane signaling receptor activity
EXW27_28965	COG4166	transmembrane transport
EXW27_28980	COG4974	Belongs to the 'phage' integrase family
EXW27_29045	COG1960	acyl-CoA dehydrogenase activity
EXW27_29050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW27_29090	COG0189	ligase activity
EXW27_29110	COG4974	Belongs to the 'phage' integrase family
EXW27_29150	COG0457	Tetratricopeptide repeat
EXW27_29235	COG0686	Belongs to the AlaDH PNT family
EXW27_29240	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW27_29240	COG2508	Transcriptional regulator
EXW27_29250	COG2124	cytochrome p450
EXW27_29275	COG1476	TRANSCRIPTIONal
EXW27_29285	COG2755	lipolytic protein G-D-S-L family
EXW27_29285	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW27_29400	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EXW27_29405	COG1518	maintenance of DNA repeat elements
EXW27_29535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW27_29540	COG0653	protein targeting
EXW27_29555	COG2222	sugar isomerase
EXW27_29565	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW27_29570	COG3715	PTS system
EXW27_29575	COG3716	PTS system mannose fructose sorbose family IID component
EXW27_29595	COG3684	Belongs to the aldolase LacD family
EXW27_29600	COG2188	Transcriptional regulator
EXW27_29745	COG0367	asparagine synthase
EXW27_29810	COG2755	lipolytic protein G-D-S-L family
EXW27_29810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW27_29820	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW27_29825	COG1288	antiporter activity
EXW27_29900	COG0463	Glycosyl transferase, family 2
EXW27_29905	COG0463	Glycosyl transferase, family 2
EXW27_29910	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW27_29915	COG1086	Polysaccharide biosynthesis protein
EXW27_29920	COG1088	dTDP-glucose 4,6-dehydratase activity
EXW27_29925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW27_29930	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW27_29945	COG2089	acid synthase
EXW27_29950	COG4641	Protein conserved in bacteria
EXW27_30010	COG0745	RESPONSE REGULATOR receiver
EXW27_30015	COG2205	protein histidine kinase activity
EXW27_30030	COG1136	(ABC) transporter
EXW27_30035	COG0577	efflux transmembrane transporter activity
EXW27_30045	COG2002	toxin-antitoxin pair type II binding
EXW27_30055	COG1923	regulation of RNA biosynthetic process
EXW27_30085	COG2814	Major facilitator Superfamily
EXW27_30110	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW27_30120	COG2002	toxin-antitoxin pair type II binding
EXW27_30185	COG1696	Membrane protein involved in D-alanine export
EXW27_30195	COG2814	Major facilitator Superfamily
EXW27_30240	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW27_30295	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW27_30305	COG0583	DNA-binding transcription factor activity
EXW27_30310	COG0768	penicillin binding
EXW27_30320	COG4990	cell redox homeostasis
EXW27_30325	COG0745	RESPONSE REGULATOR receiver
EXW27_30330	COG5002	protein histidine kinase activity
EXW27_30345	COG0745	RESPONSE REGULATOR receiver
EXW27_30370	COG0833	amino acid
EXW27_30375	COG1285	pathogenesis
EXW27_30380	COG2267	carboxylic ester hydrolase activity
EXW27_30425	COG1136	(ABC) transporter
EXW27_30450	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW27_30460	COG0772	Belongs to the SEDS family
EXW27_30465	COG2239	Acts as a magnesium transporter
EXW27_30475	COG2814	Major facilitator Superfamily
EXW27_30480	COG0583	DNA-binding transcription factor activity
EXW27_30495	COG0156	8-amino-7-oxononanoate synthase activity
EXW27_30500	COG1760	l-serine dehydratase
EXW27_30505	COG4974	Belongs to the 'phage' integrase family
EXW27_30520	COG1073	alpha beta
EXW27_30565	COG1329	Transcriptional regulator
EXW27_30575	COG0456	acetyltransferase
EXW27_30605	COG4176	ABC-type proline glycine betaine transport system permease component
EXW27_30610	COG4175	Glycine betaine
EXW27_30610	COG0517	IMP dehydrogenase activity
EXW27_30710	COG2357	RelA SpoT domain protein
EXW27_30715	COG2814	Major facilitator Superfamily
EXW27_30720	COG1309	transcriptional regulator
EXW27_30730	COG0745	RESPONSE REGULATOR receiver
EXW27_30735	COG5002	protein histidine kinase activity
EXW27_30740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW27_30795	COG2211	Major facilitator Superfamily
EXW27_30815	COG0741	lytic transglycosylase activity
EXW27_30845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW27_30860	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW27_30865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW27_30870	COG1999	signal sequence binding
EXW27_30940	COG2211	Major facilitator Superfamily
EXW27_30980	COG2002	toxin-antitoxin pair type II binding
EXW27_31050	COG0791	NLP P60 protein
EXW27_31050	COG3883	PFAM NLP P60 protein
EXW27_31060	COG0741	lytic transglycosylase activity
EXW27_31060	COG0791	NLP P60 protein
EXW27_31150	COG1396	sequence-specific DNA binding
EXW27_31180	COG2801	Transposase and inactivated derivatives
EXW27_31190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW27_31195	COG4974	Belongs to the 'phage' integrase family
EXW27_31200	COG0024	Methionine aminopeptidase
EXW27_31210	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EXW27_31395	COG1396	sequence-specific DNA binding
EXW27_31405	COG1396	sequence-specific DNA binding
EXW27_31490	COG3331	DNA recombination
EXW27_31515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW27_31530	COG5484	DNA packaging
EXW27_31535	COG1783	phage Terminase large subunit