locus-tag	class	description
DN409_00010	COG0592	DNA-directed DNA polymerase activity
DN409_00015	COG2501	S4 domain
DN409_00025	COG0187	DNA topoisomerase II activity
DN409_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DN409_00065	COG0517	IMP dehydrogenase activity
DN409_00065	COG0516	GMP reductase activity
DN409_00070	COG1686	Belongs to the peptidase S11 family
DN409_00100	COG1428	Deoxynucleoside kinase
DN409_00105	COG1428	Deoxynucleoside kinase
DN409_00110	COG1335	isochorismatase
DN409_00115	COG0590	tRNA wobble adenosine to inosine editing
DN409_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DN409_00180	COG1982	Orn Lys Arg decarboxylase major
DN409_00190	COG0470	DNA polymerase III
DN409_00195	COG1774	PSP1 C-terminal conserved region
DN409_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DN409_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DN409_00220	COG2002	toxin-antitoxin pair type II binding
DN409_00230	COG0084	hydrolase, TatD family'
DN409_00250	COG4466	Protein conserved in bacteria
DN409_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DN409_00270	COG0251	oxidation-reduction process
DN409_00275	COG2088	sporulation resulting in formation of a cellular spore
DN409_00285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DN409_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DN409_00305	COG2002	toxin-antitoxin pair type II binding
DN409_00310	COG2244	polysaccharide biosynthetic process
DN409_00315	COG3956	TIGRFAM MazG family protein
DN409_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DN409_00340	COG1098	S1 RNA binding domain
DN409_00355	COG2208	phosphoserine phosphatase activity
DN409_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DN409_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN409_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DN409_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
DN409_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN409_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DN409_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DN409_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DN409_00420	COG1396	sequence-specific DNA binding
DN409_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DN409_00520	COG3880	PFAM UvrB UvrC protein
DN409_00530	COG0542	response to heat
DN409_00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DN409_00545	COG4956	integral membrane protein (PIN domain superfamily)
DN409_00565	COG1045	serine acetyltransferase
DN409_00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN409_00585	COG3688	RNA-binding protein containing a PIN domain
DN409_00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DN409_00605	COG0250	Participates in transcription elongation, termination and antitermination
DN409_00630	COG2813	Specifically methylates the guanine in position
DN409_00645	COG1358	cellular component organization or biogenesis
DN409_00750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DN409_00775	COG0201	protein transport
DN409_00785	COG0024	Methionine aminopeptidase
DN409_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DN409_00825	COG1122	ATPase activity
DN409_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DN409_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN409_00860	COG0489	protein tyrosine kinase activity
DN409_00870	COG2194	sulfuric ester hydrolase activity
DN409_00875	COG0726	polysaccharide deacetylase
DN409_00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DN409_00960	COG4856	YbbR-like protein
DN409_00980	COG1506	peptidase
DN409_00980	COG0823	Involved in the tonB-independent uptake of proteins
DN409_00980	COG4946	Tricorn protease homolog
DN409_01005	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_01010	COG2011	ABC-type metal ion transport system permease component
DN409_01020	COG1464	Belongs to the NlpA lipoprotein family
DN409_01035	COG0277	FAD linked oxidase domain protein
DN409_01040	COG2271	Major facilitator Superfamily
DN409_01050	COG2814	Major facilitator Superfamily
DN409_01070	COG0601	transmembrane transport
DN409_01075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN409_01080	COG0444	Belongs to the ABC transporter superfamily
DN409_01085	COG4608	Belongs to the ABC transporter superfamily
DN409_01090	COG4166	transmembrane transport
DN409_01105	COG4166	transmembrane transport
DN409_01110	COG4166	transmembrane transport
DN409_01115	COG0656	L-ascorbic acid biosynthetic process
DN409_01120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN409_01135	COG4149	molybdate abc transporter
DN409_01140	COG0725	ABC transporter, periplasmic molybdate-binding protein
DN409_01145	COG1910	domain protein
DN409_01160	COG0697	spore germination
DN409_01175	COG0204	Acyl-transferase
DN409_01185	COG1609	Transcriptional regulator
DN409_01195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN409_01210	COG5298	Protein conserved in bacteria
DN409_01230	COG0488	(ABC) transporter
DN409_01235	COG4585	Histidine kinase
DN409_01245	COG1131	(ABC) transporter
DN409_01250	COG1511	domain protein
DN409_01250	COG0842	Transport permease protein
DN409_01255	COG0842	Transport permease protein
DN409_01265	COG0747	negative chemotaxis
DN409_01270	COG0601	transmembrane transport
DN409_01280	COG0444	Belongs to the ABC transporter superfamily
DN409_01285	COG4608	Belongs to the ABC transporter superfamily
DN409_01290	COG0561	phosphatase activity
DN409_01320	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DN409_01325	COG0179	Fumarylacetoacetate (FAA) hydrolase
DN409_01335	COG0531	amino acid
DN409_01340	COG2814	Major facilitator Superfamily
DN409_01350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DN409_01360	COG4294	response to UV
DN409_01365	COG0705	Rhomboid family
DN409_01375	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DN409_01380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DN409_01385	COG0864	Transcriptional regulator
DN409_01390	COG2337	Toxic component of a toxin-antitoxin (TA) module
DN409_01395	COG2183	response to ionizing radiation
DN409_01495	COG0802	atpase or kinase
DN409_01500	COG1214	PFAM Peptidase M22, glycoprotease
DN409_01505	COG0456	acetyltransferase
DN409_01515	COG0488	(ABC) transporter
DN409_01530	COG1266	CAAX protease self-immunity
DN409_01550	COG2252	PERMEase
DN409_01560	COG5002	protein histidine kinase activity
DN409_01590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DN409_01620	COG2226	methyltransferase
DN409_01640	COG1215	transferase activity, transferring glycosyl groups
DN409_01665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN409_01670	COG0506	proline dehydrogenase activity
DN409_01690	COG0697	spore germination
DN409_01720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DN409_01725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DN409_01730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DN409_01740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DN409_01755	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DN409_01765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DN409_01775	COG0151	Belongs to the GarS family
DN409_01805	COG0210	DNA helicase
DN409_01815	COG4851	CamS sex pheromone cAM373 precursor
DN409_01830	COG1335	isochorismatase
DN409_01840	COG2011	ABC-type metal ion transport system permease component
DN409_01845	COG1464	Belongs to the NlpA lipoprotein family
DN409_01860	COG0003	Pfam Anion-transporting ATPase
DN409_01865	COG1846	Transcriptional regulator
DN409_01870	COG4682	membrane
DN409_01890	COG1597	lipid kinase activity
DN409_01900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DN409_01910	COG1012	belongs to the aldehyde dehydrogenase family
DN409_01915	COG2076	Multidrug Resistance protein
DN409_01920	COG2309	aminopeptidase activity
DN409_01935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN409_01945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DN409_01950	COG5002	protein histidine kinase activity
DN409_01955	COG4807	Protein conserved in bacteria
DN409_01985	COG1473	amidohydrolase
DN409_02000	COG0450	alkyl hydroperoxide reductase
DN409_02005	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DN409_02015	COG0235	Class ii aldolase
DN409_02020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN409_02025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN409_02030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN409_02055	COG0166	Belongs to the GPI family
DN409_02080	COG5002	protein histidine kinase activity
DN409_02100	COG3541	Predicted nucleotidyltransferase
DN409_02105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN409_02105	COG0723	plastoquinol--plastocyanin reductase activity
DN409_02115	COG0765	amino acid transport
DN409_02120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN409_02130	COG0840	transmembrane signaling receptor activity
DN409_02135	COG0277	FAD linked oxidase domain protein
DN409_02140	COG0366	Alpha amylase catalytic
DN409_02145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN409_02145	COG1263	PTS System
DN409_02145	COG2190	(PTS) system
DN409_02175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DN409_02190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN409_02195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN409_02200	COG1116	anion transmembrane transporter activity
DN409_02205	COG0488	(ABC) transporter
DN409_02240	COG2270	Major facilitator Superfamily
DN409_02270	COG2310	stress, protein
DN409_02275	COG2310	stress, protein
DN409_02280	COG2310	stress, protein
DN409_02285	COG0861	Integral membrane protein TerC family
DN409_02295	COG3853	Toxic anion resistance protein (TelA)
DN409_02310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DN409_02320	COG1295	ribonuclease BN
DN409_02325	COG2217	Heavy metal translocating P-type atpase
DN409_02330	COG0697	spore germination
DN409_02355	COG0586	Pfam SNARE associated Golgi protein
DN409_02370	COG3871	stress protein (general stress protein 26)
DN409_02375	COG0387	Pfam Sodium calcium exchanger
DN409_02385	COG0535	radical SAM domain protein
DN409_02405	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DN409_02425	COG3829	transcription factor binding
DN409_02435	COG0833	amino acid
DN409_02440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DN409_02470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN409_02470	COG1263	PTS System
DN409_02475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN409_02490	COG1216	Glycosyl transferase, family 2
DN409_02500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN409_02500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DN409_02505	COG0463	Glycosyl transferase, family 2
DN409_02520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DN409_02540	COG1228	amidohydrolase
DN409_02545	COG1090	epimerase
DN409_02575	COG1988	membrane-bound metal-dependent
DN409_02580	COG1194	a g-specific adenine glycosylase
DN409_02605	COG1132	(ABC) transporter
DN409_02610	COG4129	membrane
DN409_02615	COG0069	glutamate synthase activity
DN409_02615	COG0067	glutamate synthase
DN409_02615	COG0070	glutamate synthase
DN409_02625	COG4555	ABC transporter
DN409_02645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DN409_02650	COG0735	belongs to the Fur family
DN409_02770	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DN409_02775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DN409_02795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DN409_02805	COG2766	serine protein kinase
DN409_02825	COG1585	Membrane protein implicated in regulation of membrane protease activity
DN409_02830	COG2268	Band 7 protein
DN409_02840	COG3290	protein histidine kinase activity
DN409_02845	COG4565	transcriptional regulatory protein
DN409_02850	COG2851	Citrate transporter
DN409_02875	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DN409_02880	COG3842	ATPase activity
DN409_02885	COG1175	transmembrane transport
DN409_02890	COG0395	ABC-type sugar transport system, permease component
DN409_02900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DN409_02905	COG0745	RESPONSE REGULATOR receiver
DN409_02910	COG5002	protein histidine kinase activity
DN409_02920	COG4990	cell redox homeostasis
DN409_02930	COG3290	protein histidine kinase activity
DN409_02935	COG4565	transcriptional regulatory protein
DN409_02940	COG3493	citrate carrier protein
DN409_02945	COG0281	malic enzyme
DN409_02955	COG0697	spore germination
DN409_02960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN409_02970	COG5002	protein histidine kinase activity
DN409_02975	COG0745	RESPONSE REGULATOR receiver
DN409_02980	COG0456	acetyltransferase
DN409_02985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DN409_02990	COG3383	formate dehydrogenase (NAD+) activity
DN409_03010	COG0531	amino acid
DN409_03020	COG0640	Transcriptional regulator
DN409_03025	COG2217	Heavy metal translocating P-type atpase
DN409_03030	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DN409_03040	COG3227	Zinc metalloprotease (Elastase)
DN409_03060	COG2720	vancomycin resistance protein
DN409_03065	COG1316	TRANSCRIPTIONal
DN409_03070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN409_03075	COG0346	lactoylglutathione lyase activity
DN409_03080	COG1253	flavin adenine dinucleotide binding
DN409_03085	COG1027	Aspartate ammonia-lyase
DN409_03090	COG1620	l-lactate permease
DN409_03095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN409_03115	COG3104	oligopeptide transport
DN409_03120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN409_03125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN409_03130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN409_03145	COG0156	8-amino-7-oxononanoate synthase activity
DN409_03150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN409_03160	COG4548	von Willebrand factor, type A
DN409_03165	COG0714	Associated with various cellular activities
DN409_03185	COG0531	amino acid
DN409_03190	COG2188	Transcriptional regulator
DN409_03200	COG1263	PTS System
DN409_03200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN409_03205	COG0366	Alpha amylase catalytic
DN409_03220	COG0697	spore germination
DN409_03225	COG4585	Histidine kinase
DN409_03230	COG2197	response regulator
DN409_03235	COG1404	Belongs to the peptidase S8 family
DN409_03250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DN409_03255	COG1115	amino acid carrier protein
DN409_03260	COG1126	abc transporter atp-binding protein
DN409_03265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN409_03270	COG0765	amino acid transport
DN409_03275	COG0765	amino acid transport
DN409_03280	COG0833	amino acid
DN409_03310	COG2378	regulation of single-species biofilm formation
DN409_03315	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DN409_03320	COG5002	protein histidine kinase activity
DN409_03335	COG0659	secondary active sulfate transmembrane transporter activity
DN409_03360	COG0601	transmembrane transport
DN409_03365	COG4608	Belongs to the ABC transporter superfamily
DN409_03375	COG2271	Major facilitator Superfamily
DN409_03380	COG1846	Transcriptional regulator
DN409_03385	COG0477	Major facilitator Superfamily
DN409_03390	COG1609	Transcriptional regulator
DN409_03395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN409_03410	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN409_03415	COG1879	ABC-type sugar transport system periplasmic component
DN409_03420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DN409_03445	COG1063	alcohol dehydrogenase
DN409_03460	COG3568	Endonuclease Exonuclease Phosphatase
DN409_03490	COG0840	transmembrane signaling receptor activity
DN409_03495	COG3584	3D domain protein
DN409_03495	COG3583	domain protein
DN409_03500	COG1476	TRANSCRIPTIONal
DN409_03520	COG3104	oligopeptide transport
DN409_03525	COG1114	Component of the transport system for branched-chain amino acids
DN409_03540	COG1113	amino acid transport
DN409_03545	COG2252	PERMEase
DN409_03560	COG2153	protein acetylation
DN409_03570	COG0475	glutathione-regulated potassium exporter activity
DN409_03570	COG0569	domain protein
DN409_03585	COG1845	cytochrome c oxidase, subunit III
DN409_03590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DN409_03600	COG0833	amino acid
DN409_03605	COG4990	cell redox homeostasis
DN409_03620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN409_03625	COG0697	spore germination
DN409_03630	COG0531	amino acid
DN409_03640	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DN409_03645	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DN409_03655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DN409_03660	COG0573	inorganic phosphate transmembrane transporter activity
DN409_03665	COG0581	inorganic phosphate transmembrane transporter activity
DN409_03675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN409_03795	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DN409_03810	COG4991	sh3 domain protein
DN409_03810	COG3103	Sh3 type 3 domain protein
DN409_03810	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN409_03815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DN409_03820	COG1116	anion transmembrane transporter activity
DN409_03825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN409_03830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN409_03835	COG0352	thiamine-phosphate diphosphorylase activity
DN409_03840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN409_03845	COG2104	thiamine diphosphate biosynthetic process
DN409_03855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN409_03860	COG0351	phosphomethylpyrimidine kinase
DN409_03900	COG2205	protein histidine kinase activity
DN409_03905	COG2814	Major facilitator Superfamily
DN409_03910	COG1846	Transcriptional regulator
DN409_03920	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN409_03925	COG1129	ABC transporter
DN409_03930	COG1879	ABC-type sugar transport system periplasmic component
DN409_03935	COG2252	PERMEase
DN409_03940	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_04000	COG0778	Nitroreductase
DN409_04005	COG2719	SpoVR family
DN409_04030	COG1937	Protein conserved in bacteria
DN409_04035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN409_04035	COG0425	Belongs to the sulfur carrier protein TusA family
DN409_04040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN409_04040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN409_04045	COG0425	Belongs to the sulfur carrier protein TusA family
DN409_04050	COG0425	Belongs to the sulfur carrier protein TusA family
DN409_04050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN409_04055	COG2210	Belongs to the sulfur carrier protein TusA family
DN409_04060	COG0730	response to heat
DN409_04070	COG1316	TRANSCRIPTIONal
DN409_04075	COG0604	alcohol dehydrogenase
DN409_04080	COG1283	sodium-dependent phosphate transmembrane transporter activity
DN409_04090	COG2814	Major facilitator Superfamily
DN409_04105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN409_04105	COG3711	transcriptional antiterminator
DN409_04110	COG1447	Phosphotransferase system cellobiose-specific component IIA
DN409_04115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DN409_04135	COG1388	LysM domain
DN409_04135	COG3584	3D domain protein
DN409_04140	COG0577	efflux transmembrane transporter activity
DN409_04145	COG1136	(ABC) transporter
DN409_04155	COG5522	Integral membrane protein (intg_mem_TP0381)
DN409_04170	COG0577	efflux transmembrane transporter activity
DN409_04175	COG1114	Component of the transport system for branched-chain amino acids
DN409_04180	COG3546	catalase activity
DN409_04210	COG0586	Pfam SNARE associated Golgi protein
DN409_04240	COG0531	amino acid
DN409_04245	COG0475	glutathione-regulated potassium exporter activity
DN409_04255	COG1737	Transcriptional regulator
DN409_04265	COG1263	PTS System
DN409_04265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN409_04275	COG2259	Doxx family
DN409_04295	COG0697	spore germination
DN409_04300	COG1522	sequence-specific DNA binding
DN409_04310	COG0300	oxidoreductase activity
DN409_04320	COG2076	Multidrug Resistance protein
DN409_04325	COG2076	Multidrug Resistance protein
DN409_04330	COG1309	transcriptional regulator
DN409_04335	COG2814	Major facilitator Superfamily
DN409_04340	COG1733	regulation of RNA biosynthetic process
DN409_04360	COG4533	DNA binding
DN409_04365	COG2211	Major facilitator Superfamily
DN409_04375	COG0693	protein deglycase activity
DN409_04385	COG0531	amino acid
DN409_04390	COG1012	belongs to the aldehyde dehydrogenase family
DN409_04405	COG1132	(ABC) transporter
DN409_04410	COG1132	(ABC) transporter
DN409_04415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN409_04420	COG0765	amino acid transport
DN409_04425	COG1126	abc transporter atp-binding protein
DN409_04440	COG0189	ligase activity
DN409_04470	COG0028	Belongs to the TPP enzyme family
DN409_04475	COG3527	Alpha-acetolactate decarboxylase
DN409_04480	COG0463	Glycosyl transferase, family 2
DN409_04485	COG1216	Glycosyl transferase, family 2
DN409_04495	COG0561	phosphatase activity
DN409_04505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DN409_04510	COG0318	PFAM AMP-dependent synthetase and ligase
DN409_04515	COG0586	Pfam SNARE associated Golgi protein
DN409_04525	COG4978	Transcriptional regulator
DN409_04525	COG0789	Transcriptional regulator
DN409_04535	COG0659	secondary active sulfate transmembrane transporter activity
DN409_04550	COG0653	protein targeting
DN409_04555	COG2244	polysaccharide biosynthetic process
DN409_04565	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN409_04570	COG4196	transglutaminase domain protein
DN409_04595	COG1024	Enoyl-CoA hydratase
DN409_04610	COG1363	Peptidase, m42
DN409_04625	COG2318	DinB family
DN409_04645	COG0579	oxidoreductase
DN409_04680	COG0601	transmembrane transport
DN409_04685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN409_04690	COG0444	Belongs to the ABC transporter superfamily
DN409_04695	COG4608	Belongs to the ABC transporter superfamily
DN409_04715	COG0477	Major facilitator Superfamily
DN409_04720	COG3290	protein histidine kinase activity
DN409_04725	COG4565	transcriptional regulatory protein
DN409_04730	COG3181	Tripartite tricarboxylate transporter family receptor
DN409_04760	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DN409_04810	COG0305	Participates in initiation and elongation during chromosome replication
DN409_04830	COG1842	Phage shock protein A
DN409_04840	COG0477	Major facilitator Superfamily
DN409_04880	COG1183	phosphatidylcholine synthase activity
DN409_04940	COG2732	(Barnase) inhibitor
DN409_04945	COG2814	Major facilitator Superfamily
DN409_04950	COG0640	Transcriptional regulator
DN409_04975	COG2376	Dihydroxyacetone kinase
DN409_04995	COG2376	Dihydroxyacetone kinase
DN409_05005	COG1959	2 iron, 2 sulfur cluster binding
DN409_05030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN409_05045	COG2720	vancomycin resistance protein
DN409_05075	COG0076	glutamate decarboxylase activity
DN409_05095	COG4085	toxin activity
DN409_05095	COG1525	nuclease
DN409_05095	COG0737	Belongs to the 5'-nucleotidase family
DN409_05140	COG0825	malonyl-CoA metabolic process
DN409_05165	COG2807	transmembrane transport
DN409_05180	COG4585	Histidine kinase
DN409_05185	COG2197	response regulator
DN409_05215	COG0420	3'-5' exonuclease activity
DN409_05220	COG4717	serine-type aminopeptidase activity
DN409_05230	COG0346	lactoylglutathione lyase activity
DN409_05235	COG0346	lactoylglutathione lyase activity
DN409_05240	COG0457	Tetratricopeptide repeat
DN409_05250	COG2267	carboxylic ester hydrolase activity
DN409_05265	COG3620	sequence-specific DNA binding
DN409_05270	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DN409_05275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DN409_05285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DN409_05290	COG1595	DNA-templated transcription, initiation
DN409_05305	COG3973	AAA domain
DN409_05310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DN409_05335	COG0537	adenosine 5'-monophosphoramidase activity
DN409_05340	COG1131	(ABC) transporter
DN409_05345	COG4473	ABC transporter
DN409_05410	COG1309	transcriptional regulator
DN409_05415	COG3402	PFAM membrane-flanked domain
DN409_05420	COG3428	Bacterial PH domain
DN409_05460	COG3402	PFAM membrane-flanked domain
DN409_05465	COG3428	Bacterial PH domain
DN409_05470	COG2329	Antibiotic biosynthesis monooxygenase
DN409_05475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN409_05510	COG1309	transcriptional regulator
DN409_05515	COG1511	domain protein
DN409_05550	COG1609	Transcriptional regulator
DN409_05560	COG1234	tRNA 3'-trailer cleavage
DN409_05565	COG0095	Lipoate-protein ligase
DN409_05575	COG0318	PFAM AMP-dependent synthetase and ligase
DN409_05590	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DN409_05600	COG4208	sulfate ABC transporter
DN409_05645	COG1408	metallophosphoesterase
DN409_05650	COG1078	dGTPase activity
DN409_05665	COG1595	DNA-templated transcription, initiation
DN409_05675	COG3708	Transcriptional regulator
DN409_05675	COG2207	Transcriptional regulator
DN409_05680	COG2205	protein histidine kinase activity
DN409_05685	COG0745	RESPONSE REGULATOR receiver
DN409_05705	COG0501	Belongs to the peptidase M48B family
DN409_05710	COG0697	spore germination
DN409_05735	COG0497	DNA recombination
DN409_05740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DN409_05745	COG2224	Isocitrate lyase
DN409_05755	COG1278	Cold shock
DN409_05775	COG4903	ComK protein
DN409_05785	COG0398	Pfam SNARE associated Golgi protein
DN409_05850	COG0179	Fumarylacetoacetate (FAA) hydrolase
DN409_05875	COG0367	asparagine synthase
DN409_05885	COG0753	catalase activity
DN409_05890	COG0004	ammonium transporteR
DN409_05905	COG2996	Protein conserved in bacteria
DN409_05920	COG1329	Transcriptional regulator
DN409_05955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DN409_05965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN409_05980	COG0561	phosphatase activity
DN409_06000	COG2267	carboxylic ester hydrolase activity
DN409_06015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DN409_06020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DN409_06025	COG5504	Zn-dependent protease
DN409_06045	COG0180	Tryptophanyl-tRNA synthetase
DN409_06060	COG4166	transmembrane transport
DN409_06065	COG0601	transmembrane transport
DN409_06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN409_06075	COG0444	Belongs to the ABC transporter superfamily
DN409_06080	COG4608	Belongs to the ABC transporter superfamily
DN409_06085	COG0534	Mate efflux family protein
DN409_06090	COG4166	transmembrane transport
DN409_06105	COG1393	Belongs to the ArsC family
DN409_06110	COG0861	Integral membrane protein TerC family
DN409_06115	COG4862	establishment of competence for transformation
DN409_06120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN409_06130	COG1164	Oligoendopeptidase f
DN409_06140	COG2346	COG2346, Truncated hemoglobins
DN409_06145	COG4116	CYTH
DN409_06155	COG2357	RelA SpoT domain protein
DN409_06165	COG0564	pseudouridine synthase activity
DN409_06180	COG0772	Belongs to the SEDS family
DN409_06185	COG1216	Glycosyl transferase, family 2
DN409_06205	COG0457	Tetratricopeptide repeat
DN409_06205	COG0463	Glycosyl transferase, family 2
DN409_06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DN409_06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
DN409_06285	COG2153	protein acetylation
DN409_06295	COG2382	esterase
DN409_06320	COG5492	domain, Protein
DN409_06325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN409_06345	COG0512	Glutamine amidotransferase of anthranilate synthase
DN409_06345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DN409_06380	COG1620	l-lactate permease
DN409_06385	COG5634	Uncharacterized conserved protein (DUF2278)
DN409_06435	COG2226	methyltransferase
DN409_06455	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN409_06465	COG1476	TRANSCRIPTIONal
DN409_06530	COG4974	Belongs to the 'phage' integrase family
DN409_06550	COG1686	Belongs to the peptidase S11 family
DN409_06555	COG0681	Belongs to the peptidase S26 family
DN409_06595	COG1012	belongs to the aldehyde dehydrogenase family
DN409_06605	COG1176	ABC-type spermidine putrescine transport system, permease component I
DN409_06610	COG1177	transmembrane transport
DN409_06615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DN409_06625	COG2409	Drug exporters of the RND superfamily
DN409_06635	COG0564	pseudouridine synthase activity
DN409_06645	COG2340	Cysteine-rich secretory protein family
DN409_06650	COG0247	lactate metabolic process
DN409_06655	COG0277	FAD linked oxidase domain protein
DN409_06660	COG3835	regulator
DN409_06670	COG0745	RESPONSE REGULATOR receiver
DN409_06675	COG5002	protein histidine kinase activity
DN409_06680	COG2186	Transcriptional regulator
DN409_06700	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DN409_06710	COG2116	formate transmembrane transporter activity
DN409_06715	COG0861	Integral membrane protein TerC family
DN409_06720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN409_06730	COG2030	dehydratase
DN409_06750	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_06755	COG3243	poly(R)-hydroxyalkanoic acid synthase
DN409_06765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN409_06780	COG1840	ABC-type Fe3 transport system, periplasmic component
DN409_06785	COG3842	ATPase activity
DN409_06810	COG1349	DNA-binding transcription factor activity
DN409_06820	COG0235	Class ii aldolase
DN409_06830	COG2861	carbohydrate metabolic process
DN409_06840	COG3852	Histidine kinase
DN409_06845	COG1846	Transcriptional regulator
DN409_06855	COG2318	DinB family
DN409_06860	COG5002	protein histidine kinase activity
DN409_06870	COG0720	synthase
DN409_06885	COG4873	Protein conserved in bacteria
DN409_06895	COG0456	acetyltransferase
DN409_06915	COG1780	Probably involved in ribonucleotide reductase function
DN409_06930	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DN409_06935	COG0531	amino acid
DN409_06940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DN409_06955	COG2204	response regulator
DN409_06970	COG1725	Transcriptional regulator
DN409_06975	COG1131	(ABC) transporter
DN409_06985	COG1131	(ABC) transporter
DN409_06990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DN409_06995	COG1266	CAAX protease self-immunity
DN409_07005	COG1522	sequence-specific DNA binding
DN409_07015	COG1335	isochorismatase
DN409_07025	COG1619	proteins homologs of microcin C7 resistance protein MccF
DN409_07030	COG2070	2-Nitropropane dioxygenase
DN409_07035	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DN409_07045	COG1696	Membrane protein involved in D-alanine export
DN409_07065	COG0716	FMN binding
DN409_07090	COG0534	Mate efflux family protein
DN409_07095	COG1968	undecaprenyl-diphosphatase activity
DN409_07110	COG1846	Transcriptional regulator
DN409_07120	COG1301	dicarboxylic acid transport
DN409_07125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN409_07135	COG3874	Sporulation protein YtfJ
DN409_07155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN409_07160	COG0028	Belongs to the TPP enzyme family
DN409_07165	COG0440	acetolactate synthase activity
DN409_07240	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DN409_07255	COG1183	phosphatidylcholine synthase activity
DN409_07260	COG1368	sulfuric ester hydrolase activity
DN409_07270	COG0019	diaminopimelate decarboxylase activity
DN409_07290	COG0529	Catalyzes the synthesis of activated sulfate
DN409_07295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN409_07315	COG1648	precorrin-2 dehydrogenase activity
DN409_07320	COG0733	neurotransmitter:sodium symporter activity
DN409_07340	COG1757	Na H antiporter
DN409_07360	COG4758	membrane
DN409_07365	COG4585	Histidine kinase
DN409_07370	COG2197	response regulator
DN409_07380	COG1114	Component of the transport system for branched-chain amino acids
DN409_07390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DN409_07435	COG0730	response to heat
DN409_07440	COG0306	phosphate transporter
DN409_07445	COG1392	Phosphate transport regulator
DN409_07450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN409_07465	COG3852	Histidine kinase
DN409_07470	COG1801	Protein of unknown function DUF72
DN409_07480	COG0582	viral genome integration into host DNA
DN409_07485	COG5002	protein histidine kinase activity
DN409_07500	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DN409_07500	COG0392	lysyltransferase activity
DN409_07515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DN409_07520	COG1686	Belongs to the peptidase S11 family
DN409_07525	COG2715	membrane protein required for spore maturation
DN409_07530	COG0700	Nucleoside recognition
DN409_07535	COG1187	pseudouridine synthase activity
DN409_07545	COG1333	cytochrome c biogenesis protein
DN409_07550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DN409_07555	COG0745	RESPONSE REGULATOR receiver
DN409_07560	COG5002	protein histidine kinase activity
DN409_07565	COG2096	Adenosyltransferase
DN409_07570	COG4942	peptidase
DN409_07580	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DN409_07585	COG1141	Ferredoxin
DN409_07595	COG4955	Helix-turn-helix domain
DN409_07600	COG0514	ATP-dependent DNA helicase (RecQ)
DN409_07605	COG1266	CAAX protease self-immunity
DN409_07615	COG1408	metallophosphoesterase
DN409_07630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DN409_07650	COG0492	ferredoxin-NADP+ reductase activity
DN409_07655	COG0252	asparaginase activity
DN409_07725	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DN409_07740	COG0142	geranyltranstransferase activity
DN409_07750	COG0142	geranyltranstransferase activity
DN409_07775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DN409_07780	COG0457	Tetratricopeptide repeat
DN409_07800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DN409_07815	COG4347	Protein of unknown function (DUF1405)
DN409_07830	COG2738	Putative neutral zinc metallopeptidase
DN409_07840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN409_07845	COG1694	Mazg nucleotide pyrophosphohydrolase
DN409_07860	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DN409_07865	COG0438	transferase activity, transferring glycosyl groups
DN409_07895	COG1199	ATP-dependent helicase activity
DN409_07895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DN409_07915	COG3935	DnaD domain protein
DN409_07920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DN409_07930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN409_07930	COG4499	WXG100 protein secretion system (Wss), protein YukC
DN409_07985	COG0116	Belongs to the methyltransferase superfamily
DN409_07995	COG1199	ATP-dependent helicase activity
DN409_08000	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DN409_08010	COG0024	Methionine aminopeptidase
DN409_08020	COG2233	PERMEase
DN409_08025	COG2311	Membrane
DN409_08030	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DN409_08040	COG0456	acetyltransferase
DN409_08050	COG2897	thiosulfate sulfurtransferase activity
DN409_08090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN409_08105	COG0454	-acetyltransferase
DN409_08125	COG0328	RNA-DNA hybrid ribonuclease activity
DN409_08160	COG3403	YqcI/YcgG family
DN409_08165	COG1280	lysine exporter protein (LysE YggA)
DN409_08180	COG3162	membrane
DN409_08185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN409_08190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DN409_08200	COG0475	glutathione-regulated potassium exporter activity
DN409_08205	COG0789	Transcriptional regulator
DN409_08205	COG4978	Transcriptional regulator
DN409_08215	COG2323	membrane
DN409_08220	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DN409_08280	COG1923	regulation of RNA biosynthetic process
DN409_08290	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DN409_08295	COG1360	Flagellar Motor Protein
DN409_08300	COG2201	protein-glutamate methylesterase activity
DN409_08305	COG2198	Histidine kinase
DN409_08305	COG0643	Histidine kinase
DN409_08310	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN409_08310	COG1776	CheC inhibitor of MCP methylation
DN409_08325	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DN409_08345	COG1256	bacterial-type flagellum assembly
DN409_08350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DN409_08375	COG1815	bacterial-type flagellum-dependent cell motility
DN409_08380	COG1558	bacterial-type flagellum-dependent cell motility
DN409_08385	COG1677	Flagellar hook-basal body complex protein FliE
DN409_08390	COG1766	The M ring may be actively involved in energy transduction
DN409_08395	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN409_08405	COG1157	protein secretion by the type III secretion system
DN409_08425	COG1749	Flagellar hook protein flgE
DN409_08440	COG0784	Response regulator, receiver
DN409_08440	COG0835	chemotaxis
DN409_08460	COG0861	Integral membrane protein TerC family
DN409_08470	COG3383	formate dehydrogenase (NAD+) activity
DN409_08475	COG2427	Protein of unknown function (DUF1641)
DN409_08480	COG5609	conserved protein (DUF2294)
DN409_08485	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DN409_08495	COG2116	formate transmembrane transporter activity
DN409_08500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN409_08505	COG0303	'Molybdopterin
DN409_08510	COG0314	molybdopterin synthase activity
DN409_08515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DN409_08525	COG0489	protein tyrosine kinase activity
DN409_08530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DN409_08535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DN409_08540	COG0741	lytic transglycosylase activity
DN409_08550	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN409_08555	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN409_08555	COG1776	CheC inhibitor of MCP methylation
DN409_08565	COG1338	Plays a role in the flagellum-specific transport system
DN409_08570	COG1987	bacterial-type flagellum assembly
DN409_08580	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DN409_08585	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DN409_08590	COG1419	protein localization to endoplasmic reticulum
DN409_08595	COG4786	Flagellar basal body rod
DN409_08630	COG2329	Antibiotic biosynthesis monooxygenase
DN409_08645	COG2814	Major facilitator Superfamily
DN409_08660	COG3842	ATPase activity
DN409_08670	COG1177	transmembrane transport
DN409_08740	COG0367	asparagine synthase
DN409_08770	COG1802	Transcriptional regulator
DN409_08775	COG0697	spore germination
DN409_08780	COG0438	transferase activity, transferring glycosyl groups
DN409_08780	COG1216	Glycosyl transferase, family 2
DN409_08785	COG1757	Na H antiporter
DN409_08825	COG0534	Mate efflux family protein
DN409_08830	COG3340	Belongs to the peptidase S51 family
DN409_08850	COG0785	Cytochrome C biogenesis protein
DN409_08855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN409_08875	COG2733	membrane
DN409_08915	COG1131	(ABC) transporter
DN409_08935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN409_08940	COG0528	UMP kinase activity
DN409_08950	COG1027	Aspartate ammonia-lyase
DN409_08955	COG0281	malic enzyme
DN409_08960	COG4191	Histidine kinase
DN409_08965	COG0784	Response regulator, receiver
DN409_08970	COG1846	Transcriptional regulator
DN409_08980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DN409_09000	COG3620	sequence-specific DNA binding
DN409_09035	COG1051	belongs to the nudix hydrolase family
DN409_09080	COG0477	Major facilitator Superfamily
DN409_09100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DN409_09105	COG2223	nitrite transmembrane transporter activity
DN409_09110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN409_09125	COG2244	polysaccharide biosynthetic process
DN409_09130	COG0733	neurotransmitter:sodium symporter activity
DN409_09140	COG5566	PFAM Mor transcription activator
DN409_09145	COG2323	membrane
DN409_09165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN409_09170	COG2132	Multicopper oxidase
DN409_09180	COG5002	protein histidine kinase activity
DN409_09185	COG0745	RESPONSE REGULATOR receiver
DN409_09200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DN409_09225	COG2814	Major facilitator Superfamily
DN409_09230	COG3384	dioxygenase
DN409_09285	COG4166	transmembrane transport
DN409_09320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN409_09340	COG1914	H( )-stimulated, divalent metal cation uptake system
DN409_09355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DN409_09360	COG0531	amino acid
DN409_09395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DN409_09415	COG2390	Transcriptional regulator
DN409_09430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN409_09435	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DN409_09450	COG4846	Membrane protein involved in cytochrome C biogenesis
DN409_09470	COG0583	DNA-binding transcription factor activity
DN409_09485	COG0006	proline dipeptidase activity
DN409_09490	COG2132	Multicopper oxidase
DN409_09515	COG0583	DNA-binding transcription factor activity
DN409_09535	COG1114	Component of the transport system for branched-chain amino acids
DN409_09545	COG1834	amidinotransferase
DN409_09555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN409_09600	COG2372	response to copper ion
DN409_09600	COG1276	copper resistance
DN409_09605	COG4549	nuclear export factor GLE1
DN409_09615	COG0697	spore germination
DN409_09620	COG0583	DNA-binding transcription factor activity
DN409_09625	COG1959	2 iron, 2 sulfur cluster binding
DN409_09630	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DN409_09635	COG0778	Nitroreductase
DN409_09650	COG0628	permease
DN409_09665	COG1231	oxidoreductase activity
DN409_09670	COG0523	cobalamin synthesis protein
DN409_09680	COG0411	ABC transporter
DN409_09690	COG0559	Belongs to the binding-protein-dependent transport system permease family
DN409_09700	COG0583	DNA-binding transcription factor activity
DN409_09710	COG1942	4-Oxalocrotonate Tautomerase
DN409_09725	COG0346	lactoylglutathione lyase activity
DN409_09735	COG1271	oxidase subunit
DN409_09740	COG1294	oxidase, subunit
DN409_09745	COG4988	ABC transporter
DN409_09750	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DN409_09780	COG1686	Belongs to the peptidase S11 family
DN409_09795	COG1388	LysM domain
DN409_09795	COG0791	NLP P60 protein
DN409_09805	COG1132	(ABC) transporter
DN409_09810	COG0745	RESPONSE REGULATOR receiver
DN409_09815	COG5002	protein histidine kinase activity
DN409_09820	COG0300	oxidoreductase activity
DN409_09835	COG0726	polysaccharide deacetylase
DN409_09840	COG5658	integral membrane protein
DN409_09855	COG0460	homoserine dehydrogenase
DN409_09880	COG1316	TRANSCRIPTIONal
DN409_09890	COG0745	RESPONSE REGULATOR receiver
DN409_09895	COG5002	protein histidine kinase activity
DN409_09900	COG0726	polysaccharide deacetylase
DN409_09920	COG1285	pathogenesis
DN409_09925	COG1247	-acetyltransferase
DN409_09935	COG4264	IucA IucC family
DN409_09940	COG0318	PFAM AMP-dependent synthetase and ligase
DN409_09955	COG1082	Xylose isomerase domain protein TIM barrel
DN409_09965	COG2814	Major facilitator Superfamily
DN409_09970	COG1279	arginine transmembrane transporter activity
DN409_09975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN409_09985	COG1752	Esterase of the alpha-beta hydrolase superfamily
DN409_10020	COG0577	efflux transmembrane transporter activity
DN409_10025	COG2002	toxin-antitoxin pair type II binding
DN409_10030	COG1404	Belongs to the peptidase S8 family
DN409_10040	COG3842	ATPase activity
DN409_10045	COG2508	Transcriptional regulator
DN409_10055	COG1653	transport
DN409_10060	COG1175	transmembrane transport
DN409_10065	COG0395	ABC-type sugar transport system, permease component
DN409_10070	COG5426	von Willebrand factor, type A
DN409_10075	COG1940	carbohydrate kinase activity
DN409_10080	COG2222	sugar isomerase
DN409_10090	COG1105	Belongs to the carbohydrate kinase PfkB family
DN409_10095	COG3684	Belongs to the aldolase LacD family
DN409_10100	COG0366	Alpha amylase catalytic
DN409_10110	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DN409_10115	COG0640	Transcriptional regulator
DN409_10120	COG0667	Aldo Keto reductase
DN409_10125	COG2814	Major facilitator Superfamily
DN409_10170	COG3949	Membrane
DN409_10175	COG0783	Belongs to the Dps family
DN409_10190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN409_10200	COG1231	oxidoreductase activity
DN409_10205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN409_10210	COG4989	oxidoreductase activity
DN409_10215	COG0523	cobalamin synthesis protein
DN409_10220	COG0456	acetyltransferase
DN409_10225	COG0803	Belongs to the bacterial solute-binding protein 9 family
DN409_10245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DN409_10255	COG4166	transmembrane transport
DN409_10270	COG0406	alpha-ribazole phosphatase activity
DN409_10280	COG5337	Spore coat protein CotH
DN409_10285	COG1051	belongs to the nudix hydrolase family
DN409_10290	COG0586	Pfam SNARE associated Golgi protein
DN409_10295	COG2244	polysaccharide biosynthetic process
DN409_10305	COG0701	Predicted permease
DN409_10310	COG3689	TIGRFAM TIGR03943 family protein
DN409_10315	COG1607	acyl-coa hydrolase
DN409_10325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN409_10340	COG0702	epimerase
DN409_10345	COG2839	Protein conserved in bacteria
DN409_10350	COG1253	flavin adenine dinucleotide binding
DN409_10375	COG1114	Component of the transport system for branched-chain amino acids
DN409_10380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DN409_10400	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN409_10415	COG1876	peptidase activity
DN409_10420	COG0494	nUDIX hydrolase
DN409_10445	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN409_10455	COG0561	phosphatase activity
DN409_10460	COG1846	Transcriptional regulator
DN409_10465	COG2814	Major facilitator Superfamily
DN409_10475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DN409_10480	COG4106	trans-aconitate 2-methyltransferase activity
DN409_10495	COG1819	glycosyl
DN409_10500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN409_10505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN409_10530	COG0456	acetyltransferase
DN409_10550	COG3874	Sporulation protein YtfJ
DN409_10575	COG2226	methyltransferase
DN409_10605	COG0604	alcohol dehydrogenase
DN409_10610	COG1595	DNA-templated transcription, initiation
DN409_10635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DN409_10635	COG0426	domain, Protein
DN409_10645	COG0386	Belongs to the glutathione peroxidase family
DN409_10650	COG1305	Transglutaminase-like
DN409_10655	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DN409_10660	COG0714	Associated with various cellular activities
DN409_10665	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DN409_10670	COG1140	nitrate reductase beta subunit
DN409_10675	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DN409_10680	COG2181	nitrate reductase activity
DN409_10685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN409_10690	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DN409_10695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN409_10700	COG0303	'Molybdopterin
DN409_10705	COG0314	molybdopterin synthase activity
DN409_10715	COG2223	nitrite transmembrane transporter activity
DN409_10735	COG1648	precorrin-2 dehydrogenase activity
DN409_10745	COG1587	Uroporphyrinogen-III synthase
DN409_10745	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DN409_10750	COG2146	nitrite reductase [NAD(P)H] activity
DN409_10755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN409_10760	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DN409_10785	COG2359	stage V sporulation protein S
DN409_10795	COG1418	mRNA catabolic process
DN409_10800	COG0488	(ABC) transporter
DN409_10830	COG1413	lyase activity
DN409_10845	COG2521	methyltransferase
DN409_10845	COG2136	Putative SAM-dependent methyltransferase
DN409_10850	COG0018	arginyl-trna synthetase
DN409_10905	COG0017	Asparaginyl-tRNA synthetase
DN409_10925	COG1674	ftsk spoiiie
DN409_10950	COG5444	nuclease activity
DN409_10970	COG0733	neurotransmitter:sodium symporter activity
DN409_11000	COG2610	gluconate transmembrane transporter activity
DN409_11010	COG1794	racemase activity, acting on amino acids and derivatives
DN409_11020	COG0456	acetyltransferase
DN409_11025	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DN409_11030	COG1131	(ABC) transporter
DN409_11035	COG4473	ABC transporter
DN409_11045	COG0546	phosphoglycolate phosphatase activity
DN409_11100	COG0768	penicillin binding
DN409_11115	COG1272	protein, Hemolysin III
DN409_11125	COG0805	protein transport
DN409_11135	COG1307	EDD domain protein, DegV family
DN409_11140	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DN409_11145	COG1999	signal sequence binding
DN409_11150	COG0071	Belongs to the small heat shock protein (HSP20) family
DN409_11155	COG0367	asparagine synthase
DN409_11170	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN409_11175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN409_11180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN409_11215	COG3316	Transposase and inactivated derivatives
DN409_11225	COG2211	Major facilitator Superfamily
DN409_11250	COG1335	isochorismatase
DN409_11260	COG0668	transmembrane transport
DN409_11265	COG2203	Gaf domain
DN409_11265	COG4585	Histidine kinase
DN409_11270	COG2197	response regulator
DN409_11275	COG1737	Transcriptional regulator
DN409_11280	COG1064	alcohol dehydrogenase
DN409_11295	COG1070	Carbohydrate kinase
DN409_11305	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DN409_11325	COG1125	glycine betaine transport
DN409_11325	COG0517	IMP dehydrogenase activity
DN409_11330	COG1174	glycine betaine transport
DN409_11365	COG1253	flavin adenine dinucleotide binding
DN409_11370	COG1012	belongs to the aldehyde dehydrogenase family
DN409_11375	COG5506	Protein of unknown function (DUF1694)
DN409_11390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DN409_11395	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DN409_11400	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DN409_11405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DN409_11410	COG0456	acetyltransferase
DN409_11415	COG3829	transcription factor binding
DN409_11420	COG1509	lysine 2,3-aminomutase activity
DN409_11455	COG3064	Membrane
DN409_11455	COG4991	sh3 domain protein
DN409_11455	COG0515	serine threonine protein kinase
DN409_11465	COG0671	phosphoesterase, PA-phosphatase related
DN409_11470	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DN409_11475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN409_11555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DN409_11580	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_11600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN409_11600	COG4499	WXG100 protein secretion system (Wss), protein YukC
DN409_11610	COG2814	Major facilitator Superfamily
DN409_11620	COG0372	Belongs to the citrate synthase family
DN409_11625	COG2079	MmgE PrpD family protein
DN409_11630	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DN409_11635	COG1960	acyl-CoA dehydrogenase activity
DN409_11640	COG2084	Dehydrogenase
DN409_11650	COG1280	lysine exporter protein (LysE YggA)
DN409_11655	COG1024	Enoyl-CoA hydratase
DN409_11670	COG0420	3'-5' exonuclease activity
DN409_11690	COG2223	nitrite transmembrane transporter activity
DN409_11695	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_11700	COG1169	isochorismate synthase
DN409_11705	COG1021	2,3-dihydroxybenzoate-AMP ligase
DN409_11710	COG1535	isochorismatase
DN409_11710	COG3433	isochorismatase activity
DN409_11715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DN409_11720	COG3251	PFAM MbtH domain protein
DN409_11725	COG2814	Major facilitator Superfamily
DN409_11740	COG0776	regulation of translation
DN409_11750	COG2318	DinB family
DN409_11755	COG1115	amino acid carrier protein
DN409_11770	COG2329	Antibiotic biosynthesis monooxygenase
DN409_11785	COG1187	pseudouridine synthase activity
DN409_11790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DN409_11795	COG3655	Transcriptional regulator
DN409_11805	COG1136	(ABC) transporter
DN409_11815	COG2814	Major facilitator Superfamily
DN409_11830	COG0028	Belongs to the TPP enzyme family
DN409_11860	COG1253	flavin adenine dinucleotide binding
DN409_11895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN409_11915	COG1846	Transcriptional regulator
DN409_11930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN409_11935	COG1309	transcriptional regulator
DN409_11965	COG1247	-acetyltransferase
DN409_12005	COG0596	Alpha beta hydrolase
DN409_12020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN409_12050	COG0583	DNA-binding transcription factor activity
DN409_12055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DN409_12115	COG0583	DNA-binding transcription factor activity
DN409_12120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DN409_12125	COG2258	MOSC domain
DN409_12140	COG1132	(ABC) transporter
DN409_12145	COG1132	(ABC) transporter
DN409_12165	COG1396	sequence-specific DNA binding
DN409_12270	COG1278	Cold shock
DN409_12305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DN409_12315	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
DN409_12320	COG1595	DNA-templated transcription, initiation
DN409_12340	COG1649	PFAM Uncharacterised BCR, COG1649
DN409_12365	COG2971	BadF BadG BcrA BcrD
DN409_12375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DN409_12430	COG3615	Tellurite resistance protein tehB
DN409_12430	COG0500	methyltransferase
DN409_12440	COG0693	protein deglycase activity
DN409_12485	COG2195	Cleaves the N-terminal amino acid of tripeptides
DN409_12490	COG0110	maltose O-acetyltransferase activity
DN409_12505	COG1136	(ABC) transporter
DN409_12540	COG1136	(ABC) transporter
DN409_12545	COG0577	efflux transmembrane transporter activity
DN409_12560	COG5002	protein histidine kinase activity
DN409_12570	COG1686	Belongs to the peptidase S11 family
DN409_12600	COG0768	penicillin binding
DN409_12605	COG0745	RESPONSE REGULATOR receiver
DN409_12610	COG2205	protein histidine kinase activity
DN409_12615	COG1136	(ABC) transporter
DN409_12620	COG0577	efflux transmembrane transporter activity
DN409_12630	COG1595	DNA-templated transcription, initiation
DN409_12640	COG0768	penicillin binding
DN409_12680	COG1252	NADH dehydrogenase
DN409_12685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN409_12685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN409_12700	COG0697	spore germination
DN409_12730	COG3397	chitin binding
DN409_12735	COG0823	Involved in the tonB-independent uptake of proteins
DN409_12745	COG1408	metallophosphoesterase
DN409_12755	COG1131	(ABC) transporter
DN409_12765	COG1309	transcriptional regulator
DN409_12775	COG1960	acyl-CoA dehydrogenase activity
DN409_12780	COG0439	Biotin carboxylase
DN409_12785	COG0511	ligase activity, forming carbon-carbon bonds
DN409_12790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DN409_12795	COG1024	Enoyl-CoA hydratase
DN409_12800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DN409_12805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN409_12845	COG0572	uridine kinase
DN409_12850	COG2318	DinB family
DN409_12880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DN409_12905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DN409_12930	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_12935	COG1733	regulation of RNA biosynthetic process
DN409_12960	COG1309	transcriptional regulator
DN409_12975	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DN409_12990	COG0697	spore germination
DN409_12995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN409_13020	COG1063	alcohol dehydrogenase
DN409_13030	COG2323	membrane
DN409_13045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN409_13050	COG0697	spore germination
DN409_13070	COG0201	protein transport
DN409_13080	COG0737	Belongs to the 5'-nucleotidase family
DN409_13085	COG3227	Zinc metalloprotease (Elastase)
DN409_13090	COG1523	belongs to the glycosyl hydrolase 13 family
DN409_13105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN409_13110	COG1073	alpha beta
DN409_13120	COG0577	efflux transmembrane transporter activity
DN409_13125	COG1136	(ABC) transporter
DN409_13155	COG5002	protein histidine kinase activity
DN409_13160	COG0745	RESPONSE REGULATOR receiver
DN409_13190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN409_13195	COG1183	phosphatidylcholine synthase activity
DN409_13210	COG1132	(ABC) transporter
DN409_13220	COG3961	Belongs to the TPP enzyme family
DN409_13240	COG0322	excinuclease ABC activity
DN409_13280	COG4667	esterase of the alpha-beta hydrolase superfamily
DN409_13305	COG3878	Protein conserved in bacteria
DN409_13330	COG1051	belongs to the nudix hydrolase family
DN409_13335	COG0592	DNA-directed DNA polymerase activity
DN409_13340	COG2816	NAD+ diphosphatase activity
DN409_13350	COG2223	nitrite transmembrane transporter activity
DN409_13385	COG0697	spore germination
DN409_13400	COG0584	glycerophosphoryl diester phosphodiesterase
DN409_13415	COG1733	regulation of RNA biosynthetic process
DN409_13425	COG2814	Major facilitator Superfamily
DN409_13445	COG1132	(ABC) transporter
DN409_13480	COG0671	phosphoesterase, PA-phosphatase related
DN409_13485	COG0604	alcohol dehydrogenase
DN409_13490	COG5002	protein histidine kinase activity
DN409_13495	COG0745	RESPONSE REGULATOR receiver
DN409_13515	COG2205	protein histidine kinase activity
DN409_13530	COG1122	ATPase activity
DN409_13540	COG1794	racemase activity, acting on amino acids and derivatives
DN409_13545	COG1819	glycosyl
DN409_13560	COG5002	protein histidine kinase activity
DN409_13565	COG0561	phosphatase activity
DN409_13615	COG2124	cytochrome p450
DN409_13670	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DN409_13680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN409_13685	COG0460	homoserine dehydrogenase
DN409_13705	COG0577	efflux transmembrane transporter activity
DN409_13710	COG1136	(ABC) transporter
DN409_13720	COG2211	Major facilitator Superfamily
DN409_13750	COG0667	Aldo Keto reductase
DN409_13755	COG0583	DNA-binding transcription factor activity
DN409_13780	COG2205	protein histidine kinase activity
DN409_13785	COG0745	RESPONSE REGULATOR receiver
DN409_13795	COG3773	Cell wall hydrolase
DN409_13800	COG0604	alcohol dehydrogenase
DN409_13830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN409_13845	COG2959	enzyme of heme biosynthesis
DN409_13850	COG3409	Peptidoglycan-binding domain 1 protein
DN409_13850	COG3773	Cell wall hydrolase
DN409_13885	COG1309	transcriptional regulator
DN409_13900	COG3284	Transcriptional regulator
DN409_13915	COG1349	DNA-binding transcription factor activity
DN409_13935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN409_13940	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN409_13945	COG0022	dehydrogenase e1 component
DN409_13950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DN409_13965	COG2207	Transcriptional regulator
DN409_13970	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_13975	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DN409_13975	COG0456	acetyltransferase
DN409_14010	COG4176	ABC-type proline glycine betaine transport system permease component
DN409_14015	COG0517	IMP dehydrogenase activity
DN409_14015	COG4175	Glycine betaine
DN409_14045	COG2153	protein acetylation
DN409_14050	COG3397	chitin binding
DN409_14060	COG1819	glycosyl
DN409_14075	COG2205	protein histidine kinase activity
DN409_14080	COG2315	Protein conserved in bacteria
DN409_14135	COG3973	AAA domain
DN409_14150	COG2105	PFAM AIG2 family protein
DN409_14155	COG0514	ATP-dependent DNA helicase (RecQ)
DN409_14175	COG4637	Psort location Cytoplasmic, score
DN409_14195	COG3397	chitin binding
DN409_14200	COG2318	DinB family
DN409_14220	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DN409_14225	COG1115	amino acid carrier protein
DN409_14230	COG1012	belongs to the aldehyde dehydrogenase family
DN409_14235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN409_14245	COG3938	Belongs to the proline racemase family
DN409_14250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN409_14290	COG0586	Pfam SNARE associated Golgi protein
DN409_14305	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DN409_14310	COG4166	transmembrane transport
DN409_14320	COG4948	Mandelate Racemase Muconate Lactonizing
DN409_14340	COG0667	Aldo Keto reductase
DN409_14380	COG2936	dipeptidyl-peptidase activity
DN409_14390	COG0745	RESPONSE REGULATOR receiver
DN409_14410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DN409_14415	COG1164	Oligoendopeptidase f
DN409_14430	COG1307	EDD domain protein, DegV family
DN409_14460	COG1335	isochorismatase
DN409_14475	COG2814	Major facilitator Superfamily
DN409_14485	COG1664	Polymer-forming cytoskeletal
DN409_14490	COG0789	Transcriptional regulator
DN409_14495	COG4533	DNA binding
DN409_14500	COG0477	Major facilitator Superfamily
DN409_14500	COG2814	Major facilitator Superfamily
DN409_14515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DN409_14520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DN409_14525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN409_14530	COG0438	transferase activity, transferring glycosyl groups
DN409_14535	COG3328	transposase activity
DN409_14555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DN409_14560	COG0438	transferase activity, transferring glycosyl groups
DN409_14565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DN409_14580	COG2261	transglycosylase associated protein
DN409_14595	COG2226	methyltransferase
DN409_14630	COG0436	Aminotransferase
DN409_14635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DN409_14660	COG1131	(ABC) transporter
DN409_14710	COG0628	permease
DN409_14755	COG2746	aminoglycoside 3-N-acetyltransferase activity
DN409_14765	COG0697	spore germination
DN409_14790	COG4912	Dna alkylation repair
DN409_14800	COG0726	polysaccharide deacetylase
DN409_14815	COG2814	Major facilitator Superfamily
DN409_14820	COG1368	sulfuric ester hydrolase activity
DN409_14830	COG0488	(ABC) transporter
DN409_14835	COG2409	Drug exporters of the RND superfamily
DN409_14835	COG1033	growth of symbiont in host cell
DN409_14845	COG1309	transcriptional regulator
DN409_14850	COG0494	nUDIX hydrolase
DN409_14870	COG0287	Prephenate dehydrogenase
DN409_14885	COG1605	Chorismate mutase
DN409_14885	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DN409_14915	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DN409_14930	COG3584	3D domain protein
DN409_14930	COG1388	LysM domain
DN409_14940	COG0346	lactoylglutathione lyase activity
DN409_14950	COG0431	NADPH-dependent FMN reductase
DN409_14985	COG1879	ABC-type sugar transport system periplasmic component
DN409_14990	COG2390	Transcriptional regulator
DN409_15005	COG1830	Aldolase
DN409_15010	COG2226	methyltransferase
DN409_15025	COG0346	lactoylglutathione lyase activity
DN409_15030	COG2329	Antibiotic biosynthesis monooxygenase
DN409_15055	COG2207	Transcriptional regulator
DN409_15080	COG2207	Transcriptional regulator
DN409_15100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN409_15115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN409_15120	COG3239	Fatty acid desaturase
DN409_15135	COG3655	Transcriptional regulator
DN409_15180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN409_15185	COG0346	lactoylglutathione lyase activity
DN409_15215	COG0714	Associated with various cellular activities
DN409_15235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DN409_15240	COG0753	catalase activity
DN409_15250	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DN409_15275	COG0714	Associated with various cellular activities
DN409_15285	COG0778	Nitroreductase
DN409_15290	COG1846	Transcriptional regulator
DN409_15330	COG1725	Transcriptional regulator
DN409_15360	COG2207	Transcriptional regulator
DN409_15365	COG0456	acetyltransferase
DN409_15380	COG0697	spore germination
DN409_15385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN409_15410	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DN409_15410	COG0456	acetyltransferase
DN409_15435	COG0730	response to heat
DN409_15445	COG0833	amino acid
DN409_15455	COG4335	DNA alkylation repair
DN409_15525	COG1984	allophanate hydrolase subunit 2
DN409_15530	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DN409_15535	COG1414	Transcriptional regulator
DN409_15555	COG1960	acyl-CoA dehydrogenase activity
DN409_15580	COG0640	Transcriptional regulator
DN409_15615	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DN409_15630	COG3848	Pyruvate phosphate dikinase
DN409_15630	COG0574	Belongs to the PEP-utilizing enzyme family
DN409_15640	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DN409_15650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN409_15680	COG1073	alpha beta
DN409_15695	COG0726	polysaccharide deacetylase
DN409_15705	COG5002	protein histidine kinase activity
DN409_15710	COG0745	RESPONSE REGULATOR receiver
DN409_15720	COG1575	Belongs to the MenA family. Type 1 subfamily
DN409_15730	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_15730	COG3347	Dehydrogenase
DN409_15740	COG1070	Carbohydrate kinase
DN409_15745	COG0235	Class ii aldolase
DN409_15755	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN409_15765	COG4154	Belongs to the RbsD FucU family
DN409_15780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN409_15805	COG3320	Male sterility
DN409_15805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DN409_15815	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_15820	COG1522	sequence-specific DNA binding
DN409_15835	COG0346	lactoylglutathione lyase activity
DN409_15865	COG2226	methyltransferase
DN409_15875	COG2814	Major facilitator Superfamily
DN409_15905	COG0745	RESPONSE REGULATOR receiver
DN409_15910	COG3850	Histidine kinase
DN409_15910	COG5002	protein histidine kinase activity
DN409_15940	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DN409_15955	COG2309	aminopeptidase activity
DN409_15965	COG1690	Belongs to the RtcB family
DN409_15980	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DN409_16000	COG1136	(ABC) transporter
DN409_16005	COG0577	efflux transmembrane transporter activity
DN409_16025	COG3850	Histidine kinase
DN409_16025	COG5002	protein histidine kinase activity
DN409_16035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN409_16050	COG1619	proteins homologs of microcin C7 resistance protein MccF
DN409_16070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DN409_16100	COG5444	nuclease activity
DN409_16150	COG2814	Major facilitator Superfamily
DN409_16185	COG0477	Major facilitator Superfamily
DN409_16200	COG1846	Transcriptional regulator
DN409_16205	COG2814	Major facilitator Superfamily
DN409_16220	COG3316	Transposase and inactivated derivatives
DN409_16235	COG0789	Transcriptional regulator
DN409_16270	COG1476	TRANSCRIPTIONal
DN409_16285	COG1288	antiporter activity
DN409_16290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DN409_16335	COG3718	enzyme involved in inositol metabolism
DN409_16340	COG0191	fructose-bisphosphate aldolase activity
DN409_16365	COG0673	inositol 2-dehydrogenase activity
DN409_16375	COG2814	Major facilitator Superfamily
DN409_16380	COG1609	Transcriptional regulator
DN409_16505	COG0419	ATPase involved in DNA repair
DN409_16575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DN409_16635	COG0457	Tetratricopeptide repeat
DN409_16695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN409_16755	COG4187	Peptidase family M20/M25/M40
DN409_16775	COG2890	protein-(glutamine-N5) methyltransferase activity
DN409_16780	COG2031	fatty acid transporter
DN409_16790	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN409_16830	COG1122	ATPase activity
DN409_16850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DN409_16855	COG1288	antiporter activity
DN409_16860	COG2356	endonuclease I
DN409_16865	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DN409_16885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DN409_16905	COG1785	Belongs to the alkaline phosphatase family
DN409_16910	COG0778	Nitroreductase
DN409_16915	COG1733	regulation of RNA biosynthetic process
DN409_16930	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_16940	COG1131	(ABC) transporter
DN409_16970	COG1595	DNA-templated transcription, initiation
DN409_16985	COG1011	Hydrolase
DN409_17010	COG0346	lactoylglutathione lyase activity
DN409_17015	COG1940	carbohydrate kinase activity
DN409_17020	COG0738	Major facilitator superfamily
DN409_17025	COG0110	maltose O-acetyltransferase activity
DN409_17030	COG0180	Tryptophanyl-tRNA synthetase
DN409_17040	COG0628	permease
DN409_17045	COG2261	transglycosylase associated protein
DN409_17090	COG1253	flavin adenine dinucleotide binding
DN409_17095	COG0789	Transcriptional regulator
DN409_17100	COG0697	spore germination
DN409_17110	COG1357	PFAM Pentapeptide repeats (8 copies)
DN409_17115	COG3813	Protein conserved in bacteria
DN409_17120	COG2706	6-phosphogluconolactonase activity
DN409_17125	COG1070	Carbohydrate kinase
DN409_17135	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DN409_17140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DN409_17155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN409_17175	COG0384	phenazine biosynthesis protein PhzF
DN409_17195	COG0318	PFAM AMP-dependent synthetase and ligase
DN409_17200	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN409_17205	COG1733	regulation of RNA biosynthetic process
DN409_17220	COG1191	sigma factor activity
DN409_17245	COG1876	peptidase activity
DN409_17285	COG0741	lytic transglycosylase activity
DN409_17320	COG0745	RESPONSE REGULATOR receiver
DN409_17345	COG2211	Major facilitator Superfamily
DN409_17365	COG2814	Major facilitator Superfamily
DN409_17370	COG1309	transcriptional regulator
DN409_17390	COG2224	Isocitrate lyase
DN409_17420	COG0814	amino acid
DN409_17445	COG1151	hydroxylamine reductase activity
DN409_17475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN409_17485	COG2072	flavoprotein involved in K transport
DN409_17530	COG1695	Transcriptional regulator
DN409_17535	COG0604	alcohol dehydrogenase
DN409_17540	COG1113	amino acid transport
DN409_17550	COG2814	Major facilitator Superfamily
DN409_17565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DN409_17580	COG0534	Mate efflux family protein
DN409_17605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DN409_17610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DN409_17630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN409_17635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN409_17640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN409_17645	COG3739	integral membrane protein
DN409_17670	COG0583	DNA-binding transcription factor activity
DN409_17690	COG1193	negative regulation of DNA recombination
DN409_17710	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DN409_17715	COG1164	Oligoendopeptidase f
DN409_17720	COG2957	Belongs to the agmatine deiminase family
DN409_17740	COG3781	membrane
DN409_17755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN409_17790	COG3973	AAA domain
DN409_17800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DN409_17805	COG0640	Transcriptional regulator
DN409_17810	COG0604	alcohol dehydrogenase
DN409_17825	COG0457	Tetratricopeptide repeat
DN409_17830	COG2808	Putative FMN-binding domain
DN409_17845	COG0277	FAD linked oxidase domain protein
DN409_17865	COG1285	pathogenesis
DN409_17875	COG2514	catechol 2,3-dioxygenase activity
DN409_17880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN409_17885	COG1126	abc transporter atp-binding protein
DN409_17890	COG0765	amino acid transport
DN409_17895	COG2720	vancomycin resistance protein
DN409_17920	COG1278	Cold shock
DN409_17930	COG0716	FMN binding
DN409_17960	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_17970	COG0165	Argininosuccinate lyase
DN409_17985	COG4145	pantothenate transmembrane transporter activity
DN409_17995	COG1012	belongs to the aldehyde dehydrogenase family
DN409_18000	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_18010	COG1657	PFAM Prenyltransferase squalene oxidase
DN409_18015	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DN409_18020	COG2962	Rard protein
DN409_18025	COG3326	Membrane
DN409_18030	COG0531	amino acid
DN409_18060	COG2226	methyltransferase
DN409_18065	COG4166	transmembrane transport
DN409_18070	COG4166	transmembrane transport
DN409_18075	COG4166	transmembrane transport
DN409_18080	COG1316	TRANSCRIPTIONal
DN409_18090	COG1595	DNA-templated transcription, initiation
DN409_18100	COG1131	(ABC) transporter
DN409_18120	COG0673	inositol 2-dehydrogenase activity
DN409_18125	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DN409_18130	COG0187	DNA topoisomerase II activity
DN409_18135	COG1832	CoA-binding protein
DN409_18140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN409_18145	COG0745	RESPONSE REGULATOR receiver
DN409_18155	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DN409_18155	COG1328	CTP reductase activity
DN409_18165	COG4841	protein insertion into membrane
DN409_18170	COG0824	Thioesterase
DN409_18195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN409_18230	COG1132	(ABC) transporter
DN409_18235	COG1266	CAAX protease self-immunity
DN409_18240	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DN409_18250	COG0726	polysaccharide deacetylase
DN409_18270	COG2211	Major facilitator Superfamily
DN409_18280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DN409_18295	COG0183	Belongs to the thiolase family
DN409_18300	COG0318	PFAM AMP-dependent synthetase and ligase
DN409_18305	COG1268	BioY protein
DN409_18310	COG0318	PFAM AMP-dependent synthetase and ligase
DN409_18360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN409_18375	COG5002	protein histidine kinase activity
DN409_18385	COG0400	carboxylic ester hydrolase activity
DN409_18390	COG0346	lactoylglutathione lyase activity
DN409_18395	COG0069	glutamate synthase activity
DN409_18400	COG1902	pentaerythritol trinitrate reductase activity
DN409_18410	COG1329	Transcriptional regulator
DN409_18415	COG0010	Belongs to the arginase family
DN409_18440	COG2226	methyltransferase
DN409_18470	COG4846	Membrane protein involved in cytochrome C biogenesis
DN409_18475	COG0785	Cytochrome C biogenesis protein
DN409_18495	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DN409_18500	COG1131	(ABC) transporter
DN409_18510	COG0583	DNA-binding transcription factor activity
DN409_18520	COG1346	cytolysis
DN409_18535	COG0730	response to heat
DN409_18545	COG3409	Peptidoglycan-binding domain 1 protein
DN409_18545	COG5632	N-Acetylmuramoyl-L-alanine amidase
DN409_18565	COG1132	(ABC) transporter
DN409_18570	COG1132	(ABC) transporter
DN409_18595	COG3639	organic phosphonate transmembrane transporter activity
DN409_18605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN409_18610	COG0737	Belongs to the 5'-nucleotidase family
DN409_18620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DN409_18640	COG1695	Transcriptional regulator
DN409_18645	COG1132	(ABC) transporter
DN409_18680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DN409_18690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DN409_18700	COG5434	Belongs to the glycosyl hydrolase 28 family
DN409_18700	COG3420	alginic acid biosynthetic process
DN409_18710	COG1442	glycosyl transferase family 8
DN409_18715	COG1442	glycosyl transferase family 8
DN409_18715	COG1216	Glycosyl transferase, family 2
DN409_18730	COG0297	glycogen (starch) synthase activity
DN409_18740	COG0438	transferase activity, transferring glycosyl groups
DN409_18750	COG1215	transferase activity, transferring glycosyl groups
DN409_18755	COG0438	transferase activity, transferring glycosyl groups
DN409_18760	COG0438	transferase activity, transferring glycosyl groups
DN409_18765	COG1086	Polysaccharide biosynthesis protein
DN409_18770	COG0489	protein tyrosine kinase activity
DN409_18775	COG3944	biosynthesis protein
DN409_18780	COG0174	glutamine synthetase
DN409_18785	COG0789	Transcriptional regulator
DN409_18790	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DN409_18795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DN409_18800	COG2860	membrane
DN409_18805	COG0464	growth
DN409_18835	COG3584	3D domain protein
DN409_18835	COG1388	LysM domain
DN409_18840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN409_18840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN409_18840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN409_18845	COG1105	Belongs to the carbohydrate kinase PfkB family
DN409_18850	COG1349	DNA-binding transcription factor activity
DN409_18855	COG1979	alcohol dehydrogenase
DN409_18860	COG2322	membrane
DN409_18870	COG1113	amino acid transport
DN409_18885	COG1473	amidohydrolase
DN409_18890	COG1408	metallophosphoesterase
DN409_18895	COG2116	formate transmembrane transporter activity
DN409_18910	COG2217	Heavy metal translocating P-type atpase
DN409_18915	COG2608	mercury ion transmembrane transporter activity
DN409_18920	COG1937	Protein conserved in bacteria
DN409_18940	COG2819	hydrolase of the alpha beta superfamily
DN409_18945	COG1120	ATPase activity
DN409_18950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN409_18955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN409_18960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN409_18965	COG0708	Exodeoxyribonuclease III
DN409_18970	COG2169	Transcriptional regulator
DN409_18975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DN409_18980	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DN409_18985	COG2706	6-phosphogluconolactonase activity
DN409_18995	COG2364	Membrane
DN409_19005	COG0346	lactoylglutathione lyase activity
DN409_19010	COG3300	MHYT domain
DN409_19010	COG5001	Diguanylate cyclase
DN409_19050	COG1346	cytolysis
DN409_19060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN409_19065	COG0596	Alpha beta hydrolase
DN409_19065	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN409_19070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DN409_19080	COG2188	Transcriptional regulator
DN409_19085	COG2723	6-phospho-beta-galactosidase activity
DN409_19095	COG3773	Cell wall hydrolase
DN409_19105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DN409_19115	COG2723	6-phospho-beta-galactosidase activity
DN409_19120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN409_19120	COG2190	(PTS) system
DN409_19120	COG1263	PTS System
DN409_19125	COG3711	transcriptional antiterminator
DN409_19135	COG0640	Transcriptional regulator
DN409_19140	COG0697	spore germination
DN409_19145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN409_19165	COG4550	Control of competence regulator ComK, YlbF/YmcA
DN409_19175	COG1013	pyruvate-flavodoxin oxidoreductase activity
DN409_19180	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DN409_19180	COG0674	pyruvate-flavodoxin oxidoreductase activity
DN409_19190	COG2359	stage V sporulation protein S
DN409_19195	COG1692	metallophosphoesterase
DN409_19215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DN409_19220	COG1426	Protein conserved in bacteria
DN409_19235	COG0300	oxidoreductase activity
DN409_19240	COG0612	Peptidase, M16
DN409_19245	COG0612	Peptidase, M16
DN409_19270	COG2188	Transcriptional regulator
DN409_19280	COG1674	ftsk spoiiie
DN409_19290	COG0740	serine-type endopeptidase activity
DN409_19295	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DN409_19305	COG0527	aspartate kinase activity
DN409_19310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DN409_19315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DN409_19320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DN409_19325	COG1873	PFAM PRC-barrel domain
DN409_19330	COG0612	Peptidase, M16
DN409_19335	COG0726	polysaccharide deacetylase
DN409_19350	COG0196	riboflavin kinase activity
DN409_19365	COG1550	Protein conserved in bacteria
DN409_19375	COG1358	cellular component organization or biogenesis
DN409_19380	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DN409_19385	COG0195	Participates in both transcription termination and antitermination
DN409_19405	COG0750	zinc metalloprotease
DN409_19415	COG4589	Belongs to the CDS family
DN409_19430	COG0528	UMP kinase activity
DN409_19460	COG4974	Belongs to the 'phage' integrase family
DN409_19470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DN409_19475	COG0758	DNA mediated transformation
DN409_19480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DN409_19520	COG1837	Belongs to the UPF0109 family
DN409_19530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DN409_19540	COG0552	protein localization to endoplasmic reticulum
DN409_19545	COG1196	nuclear chromosome segregation
DN409_19560	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_19565	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DN409_19580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DN409_19585	COG1461	Dihydroxyacetone kinase
DN409_19590	COG1302	Protein conserved in bacteria
DN409_19605	COG1564	THIamine pyrophosphokinase
DN409_19610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DN409_19620	COG0515	serine threonine protein kinase
DN409_19620	COG2815	serine threonine protein kinase
DN409_19625	COG0631	protein serine/threonine phosphatase activity
DN409_19635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DN409_19635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DN409_19645	COG0242	peptide deformylase activity
DN409_19650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DN409_19655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DN409_19665	COG0194	GDP metabolic process
DN409_19675	COG1561	YicC-like family, N-terminal region
DN409_19680	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DN409_19695	COG0006	proline dipeptidase activity
DN409_19715	COG3069	C4-dicarboxylate transmembrane transporter activity
DN409_19775	COG0564	pseudouridine synthase activity
DN409_19795	COG3599	regulation of cell shape
DN409_19800	COG2302	S4 RNA-binding domain
DN409_19805	COG0762	integral membrane protein
DN409_19815	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DN409_19825	COG1873	PFAM PRC-barrel domain
DN409_19830	COG1191	sigma factor activity
DN409_19835	COG1191	sigma factor activity
DN409_19845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DN409_19850	COG0849	cell division
DN409_19855	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DN409_19865	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DN409_19870	COG0772	Belongs to the SEDS family
DN409_19885	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DN409_19890	COG0768	penicillin binding
DN409_19915	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DN409_19935	COG1399	metal-binding, possibly nucleic acid-binding protein
DN409_19945	COG3480	Lon protease (S16) C-terminal proteolytic domain
DN409_19950	COG1752	Esterase of the alpha-beta hydrolase superfamily
DN409_19955	COG3314	Sporulation integral membrane protein YlbJ
DN409_19965	COG0742	ribosomal rna small subunit methyltransferase
DN409_19980	COG3679	Belongs to the UPF0342 family
DN409_19985	COG0406	alpha-ribazole phosphatase activity
DN409_20000	COG2340	Cysteine-rich secretory protein family
DN409_20010	COG3336	cytochrome c oxidase
DN409_20045	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DN409_20055	COG0772	Belongs to the SEDS family
DN409_20065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DN409_20070	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DN409_20080	COG4896	Protein conserved in bacteria
DN409_20105	COG0483	inositol monophosphate 1-phosphatase activity
DN409_20125	COG1982	Orn Lys Arg decarboxylase major
DN409_20175	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN409_20180	COG0022	dehydrogenase e1 component
DN409_20185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DN409_20200	COG0561	phosphatase activity
DN409_20215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DN409_20220	COG0569	domain protein
DN409_20240	COG0583	DNA-binding transcription factor activity
DN409_20245	COG0517	IMP dehydrogenase activity
DN409_20255	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DN409_20265	COG4703	Protein of unknown function (DUF1797)
DN409_20280	COG2200	EAL domain
DN409_20285	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_20290	COG1408	metallophosphoesterase
DN409_20335	COG2814	Major facilitator Superfamily
DN409_20355	COG3209	COG3209 Rhs family protein
DN409_20365	COG2205	protein histidine kinase activity
DN409_20375	COG0436	Aminotransferase
DN409_20380	COG1609	Transcriptional regulator
DN409_20385	COG3833	ABC-type maltose transport systems, permease component
DN409_20390	COG1175	transmembrane transport
DN409_20395	COG2182	Extracellular solute-binding protein
DN409_20405	COG0366	Alpha amylase catalytic
DN409_20410	COG3842	ATPase activity
DN409_20455	COG0183	Belongs to the thiolase family
DN409_20490	COG1695	Transcriptional regulator
DN409_20495	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_20515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DN409_20520	COG0436	Aminotransferase
DN409_20555	COG2084	Dehydrogenase
DN409_20565	COG2203	Gaf domain
DN409_20565	COG2199	diguanylate cyclase activity
DN409_20570	COG0778	Nitroreductase
DN409_20595	COG1263	PTS System
DN409_20595	COG2190	(PTS) system
DN409_20595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN409_20600	COG3711	transcriptional antiterminator
DN409_20620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DN409_20650	COG1547	Domain of unknown function (DUF309)
DN409_20660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DN409_20665	COG4086	secreted protein
DN409_20670	COG0561	phosphatase activity
DN409_20675	COG0697	spore germination
DN409_20690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DN409_20730	COG1686	Belongs to the peptidase S11 family
DN409_20735	COG1725	Transcriptional regulator
DN409_20740	COG1131	(ABC) transporter
DN409_20760	COG1846	Transcriptional regulator
DN409_20775	COG0598	Magnesium transport protein CorA
DN409_20800	COG4974	Belongs to the 'phage' integrase family
DN409_20810	COG0735	belongs to the Fur family
DN409_20815	COG1300	Membrane
DN409_20835	COG0667	Aldo Keto reductase
DN409_20840	COG0656	L-ascorbic acid biosynthetic process
DN409_20845	COG0456	acetyltransferase
DN409_20845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DN409_20855	COG1525	nuclease
DN409_20855	COG4085	toxin activity
DN409_20855	COG0737	Belongs to the 5'-nucleotidase family
DN409_20865	COG0596	Alpha beta hydrolase
DN409_20870	COG2056	Na+-H+ antiporter family
DN409_20875	COG1609	Transcriptional regulator
DN409_20880	COG0456	acetyltransferase
DN409_20885	COG1073	alpha beta
DN409_20900	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN409_20900	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN409_20905	COG0307	riboflavin synthase, alpha
DN409_20935	COG4106	trans-aconitate 2-methyltransferase activity
DN409_20940	COG2226	methyltransferase
DN409_20940	COG1073	alpha beta
DN409_20955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DN409_20970	COG0737	Belongs to the 5'-nucleotidase family
DN409_20980	COG1522	sequence-specific DNA binding
DN409_21025	COG0300	oxidoreductase activity
DN409_21030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN409_21035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN409_21040	COG1760	l-serine dehydratase
DN409_21045	COG1760	l-serine dehydratase
DN409_21090	COG1131	(ABC) transporter
DN409_21120	COG2195	Cleaves the N-terminal amino acid of tripeptides
DN409_21125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN409_21135	COG1376	ErfK ybiS ycfS ynhG family protein
DN409_21140	COG4129	membrane
DN409_21145	COG1126	abc transporter atp-binding protein
DN409_21150	COG0765	amino acid transport
DN409_21155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN409_21175	COG2323	membrane
DN409_21180	COG0772	Belongs to the SEDS family
DN409_21185	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN409_21190	COG0022	dehydrogenase e1 component
DN409_21195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DN409_21200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN409_21210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DN409_21215	COG0280	phosphate acetyltransferase
DN409_21225	COG3829	transcription factor binding
DN409_21225	COG3290	protein histidine kinase activity
DN409_21235	COG0584	glycerophosphoryl diester phosphodiesterase
DN409_21240	COG3093	addiction module antidote protein HigA
DN409_21280	COG0745	RESPONSE REGULATOR receiver
DN409_21290	COG0750	zinc metalloprotease
DN409_21295	COG0497	DNA recombination
DN409_21305	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DN409_21315	COG0142	geranyltranstransferase activity
DN409_21340	COG1302	Protein conserved in bacteria
DN409_21345	COG0439	Biotin carboxylase
DN409_21350	COG0511	ligase activity, forming carbon-carbon bonds
DN409_21395	COG3854	ATPases associated with a variety of cellular activities
DN409_21420	COG0006	proline dipeptidase activity
DN409_21435	COG3872	metal-dependent enzyme
DN409_21445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DN409_21480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN409_21490	COG1609	Transcriptional regulator
DN409_21500	COG2076	Multidrug Resistance protein
DN409_21505	COG2076	Multidrug Resistance protein
DN409_21535	COG1131	(ABC) transporter
DN409_21540	COG1725	Transcriptional regulator
DN409_21570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DN409_21625	COG4970	Tfp pilus assembly protein FimT
DN409_21635	COG1459	type II secretion system
DN409_21640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DN409_21695	COG0646	methionine synthase
DN409_21695	COG1410	methionine synthase
DN409_21700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DN409_21700	COG0646	methionine synthase
DN409_21705	COG0626	cystathionine gamma-synthase activity
DN409_21710	COG0626	cystathionine gamma-synthase activity
DN409_21725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN409_21735	COG1940	carbohydrate kinase activity
DN409_21740	COG4483	Protein conserved in bacteria
DN409_21745	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DN409_21755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DN409_21760	COG0704	Plays a role in the regulation of phosphate uptake
DN409_21770	COG0581	inorganic phosphate transmembrane transporter activity
DN409_21775	COG0573	inorganic phosphate transmembrane transporter activity
DN409_21780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DN409_21790	COG0477	Major facilitator Superfamily
DN409_21795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DN409_21820	COG0735	belongs to the Fur family
DN409_21825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DN409_21830	COG1121	(ABC) transporter
DN409_21835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN409_21865	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DN409_21870	COG2384	SAM-dependent methyltransferase
DN409_21880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DN409_21885	COG0358	DNA primase activity
DN409_21900	COG0517	IMP dehydrogenase activity
DN409_21915	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DN409_21920	COG0295	cytidine deaminase activity
DN409_21925	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DN409_21935	COG1480	7TM receptor with intracellular HD hydrolase
DN409_21940	COG1702	phosphate starvation-inducible protein PhoH
DN409_21955	COG1610	YqeY-like protein
DN409_21965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DN409_21970	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DN409_22000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DN409_22005	COG1733	regulation of RNA biosynthetic process
DN409_22030	COG1466	dna polymerase III delta subunit
DN409_22045	COG2131	deaminase
DN409_22050	COG1596	polysaccharide export
DN409_22050	COG1555	photosystem II stabilization
DN409_22055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN409_22060	COG2226	methyltransferase
DN409_22065	COG0799	negative regulation of ribosome biogenesis
DN409_22070	COG1713	HD superfamily hydrolase involved in NAD metabolism
DN409_22080	COG1534	Rna-binding protein
DN409_22090	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DN409_22095	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DN409_22110	COG1191	sigma factor activity
DN409_22120	COG2357	RelA SpoT domain protein
DN409_22130	COG1785	Belongs to the alkaline phosphatase family
DN409_22140	COG2267	carboxylic ester hydrolase activity
DN409_22175	COG1404	Belongs to the peptidase S8 family
DN409_22180	COG3186	Phenylalanine-4-hydroxylase
DN409_22185	COG2154	pterin-4-alpha-carbinolamine dehydratase
DN409_22190	COG2514	catechol 2,3-dioxygenase activity
DN409_22195	COG2259	Doxx family
DN409_22235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN409_22245	COG1454	alcohol dehydrogenase
DN409_22245	COG1012	belongs to the aldehyde dehydrogenase family
DN409_22250	COG0626	cystathionine gamma-synthase activity
DN409_22255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN409_22280	COG0768	penicillin binding
DN409_22310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DN409_22340	COG0628	permease
DN409_22360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DN409_22375	COG1104	cysteine desulfurase activity
DN409_22380	COG1959	2 iron, 2 sulfur cluster binding
DN409_22385	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DN409_22395	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DN409_22415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DN409_22425	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DN409_22425	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DN409_22430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DN409_22435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DN409_22435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DN409_22445	COG2244	polysaccharide biosynthetic process
DN409_22450	COG2323	membrane
DN409_22460	COG1862	Preprotein translocase
DN409_22490	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DN409_22520	COG0157	Belongs to the NadC ModD family
DN409_22525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DN409_22530	COG1104	cysteine desulfurase activity
DN409_22535	COG1827	regulation of RNA biosynthetic process
DN409_22540	COG2258	MOSC domain
DN409_22545	COG0077	Prephenate dehydratase
DN409_22550	COG0577	efflux transmembrane transporter activity
DN409_22555	COG0577	efflux transmembrane transporter activity
DN409_22560	COG1136	(ABC) transporter
DN409_22565	COG5002	protein histidine kinase activity
DN409_22570	COG0745	RESPONSE REGULATOR receiver
DN409_22580	COG3290	protein histidine kinase activity
DN409_22590	COG2868	ribosomal protein
DN409_22600	COG1530	ribonuclease E activity
DN409_22610	COG1994	Peptidase M50
DN409_22615	COG0739	heme binding
DN409_22620	COG2894	cell division
DN409_22635	COG1792	Involved in formation and maintenance of cell shape
DN409_22640	COG1077	Cell shape determining protein MreB Mrl
DN409_22665	COG0285	dihydrofolate synthase activity
DN409_22680	COG1388	LysM domain
DN409_22690	COG0113	porphobilinogen synthase activity
DN409_22695	COG1587	Uroporphyrinogen-III synthase
DN409_22705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DN409_22715	COG1846	Transcriptional regulator
DN409_22720	COG1764	response to oxidative stress
DN409_22735	COG0470	DNA polymerase III
DN409_22735	COG1067	ATP-dependent peptidase activity
DN409_22825	COG0582	viral genome integration into host DNA
DN409_22865	COG0622	Phosphoesterase
DN409_22880	COG5401	PFAM Sporulation and spore germination
DN409_22890	COG2197	response regulator
DN409_22895	COG2233	PERMEase
DN409_22900	COG0402	S-adenosylhomocysteine deaminase activity
DN409_22905	COG1983	PspC domain protein
DN409_22910	COG1396	sequence-specific DNA binding
DN409_22915	COG0697	spore germination
DN409_22925	COG1959	2 iron, 2 sulfur cluster binding
DN409_22930	COG1668	transmembrane transport
DN409_22935	COG4152	abc transporter atp-binding protein
DN409_22940	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DN409_22945	COG1360	Flagellar Motor Protein
DN409_22950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DN409_22960	COG1876	peptidase activity
DN409_22965	COG0824	Thioesterase
DN409_22970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DN409_22975	COG1053	succinate dehydrogenase
DN409_22980	COG2009	succinate dehydrogenase
DN409_22985	COG1719	4-vinyl reductase, 4VR
DN409_22995	COG3118	belongs to the thioredoxin family
DN409_23000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DN409_23005	COG2086	electron transfer activity
DN409_23010	COG1024	Enoyl-CoA hydratase
DN409_23015	COG1309	transcriptional regulator
DN409_23020	COG0318	PFAM AMP-dependent synthetase and ligase
DN409_23035	COG2318	DinB family
DN409_23055	COG1131	(ABC) transporter
DN409_23060	COG2205	protein histidine kinase activity
DN409_23065	COG0745	RESPONSE REGULATOR receiver
DN409_23070	COG4895	conserved protein (DUF2196)
DN409_23075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DN409_23090	COG4509	Sortase family
DN409_23095	COG1120	ATPase activity
DN409_23110	COG5386	Cell surface protein
DN409_23120	COG5386	Cell surface protein
DN409_23125	COG1114	Component of the transport system for branched-chain amino acids
DN409_23130	COG1187	pseudouridine synthase activity
DN409_23140	COG1796	DNA polymerase
DN409_23140	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DN409_23145	COG1286	toxin biosynthetic process
DN409_23180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DN409_23180	COG0072	phenylalanine-tRNA ligase activity
DN409_23190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN409_23200	COG1418	mRNA catabolic process
DN409_23225	COG2814	Major facilitator Superfamily
DN409_23230	COG1566	PFAM secretion protein HlyD family protein
DN409_23235	COG1309	transcriptional regulator
DN409_23240	COG1363	Peptidase, m42
DN409_23260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DN409_23265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DN409_23275	COG1484	DNA-dependent DNA replication
DN409_23280	COG3611	Membrane attachment protein
DN409_23290	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DN409_23295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DN409_23300	COG0237	dephospho-CoA kinase activity
DN409_23305	COG1971	Probably functions as a manganese efflux pump
DN409_23315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN409_23315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN409_23320	COG5002	protein histidine kinase activity
DN409_23325	COG0745	RESPONSE REGULATOR receiver
DN409_23345	COG0538	isocitrate dehydrogenase activity
DN409_23350	COG0372	Belongs to the citrate synthase family
DN409_23365	COG0628	permease
DN409_23370	COG3030	protein affecting phage T7 exclusion by the F plasmid
DN409_23395	COG1725	Transcriptional regulator
DN409_23400	COG0281	malic enzyme
DN409_23405	COG0587	DNA-directed DNA polymerase activity
DN409_23420	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DN409_23440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DN409_23450	COG4109	DRTGG domain
DN409_23460	COG0006	proline dipeptidase activity
DN409_23485	COG0662	Cupin 2, conserved barrel domain protein
DN409_23495	COG1476	TRANSCRIPTIONal
DN409_23510	COG1028	Short-chain dehydrogenase reductase Sdr
DN409_23515	COG0589	response to stress
DN409_23555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN409_23580	COG0827	DNA restriction-modification system
DN409_23585	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DN409_23590	COG3874	Sporulation protein YtfJ
DN409_23605	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DN409_23615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN409_23630	COG1104	cysteine desulfurase activity
DN409_23650	COG1309	transcriptional regulator
DN409_23655	COG1956	GAF domain-containing protein
DN409_23660	COG0626	cystathionine gamma-synthase activity
DN409_23690	COG1595	DNA-templated transcription, initiation
DN409_23700	COG0110	maltose O-acetyltransferase activity
DN409_23705	COG0456	acetyltransferase
DN409_23710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN409_23715	COG0454	-acetyltransferase
DN409_23720	COG0517	IMP dehydrogenase activity
DN409_23725	COG0123	including yeast histone deacetylase and acetoin utilization protein
DN409_23730	COG2267	carboxylic ester hydrolase activity
DN409_23740	COG0745	RESPONSE REGULATOR receiver
DN409_23745	COG5002	protein histidine kinase activity
DN409_23750	COG0666	response to abiotic stimulus
DN409_23780	COG1609	Transcriptional regulator
DN409_23785	COG1605	Chorismate mutase
DN409_23785	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DN409_23790	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DN409_23790	COG1605	Chorismate mutase
DN409_23795	COG4851	CamS sex pheromone cAM373 precursor
DN409_23800	COG3118	belongs to the thioredoxin family
DN409_23810	COG2309	aminopeptidase activity
DN409_23830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN409_23845	COG1674	ftsk spoiiie
DN409_23860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DN409_23870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN409_23875	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
DN409_23880	COG1363	Peptidase, m42
DN409_23890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN409_23905	COG0510	thiamine kinase activity
DN409_23910	COG1523	belongs to the glycosyl hydrolase 13 family
DN409_23920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DN409_23925	COG1349	DNA-binding transcription factor activity
DN409_23930	COG1187	pseudouridine synthase activity
DN409_23935	COG2244	polysaccharide biosynthetic process
DN409_23940	COG2081	HI0933 family
DN409_23945	COG2814	Major facilitator Superfamily
DN409_23955	COG3832	glyoxalase III activity
DN409_23975	COG1329	Transcriptional regulator
DN409_24000	COG0314	molybdopterin synthase activity
DN409_24005	COG1763	Mo-molybdopterin cofactor biosynthetic process
DN409_24010	COG0303	'Molybdopterin
DN409_24020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN409_24025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DN409_24050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN409_24060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DN409_24105	COG2814	Major facilitator Superfamily
DN409_24110	COG0475	glutathione-regulated potassium exporter activity
DN409_24115	COG0490	domain, Protein
DN409_24120	COG0582	viral genome integration into host DNA
DN409_24130	COG1136	(ABC) transporter
DN409_24145	COG1242	4 iron, 4 sulfur cluster binding
DN409_24150	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DN409_24170	COG2267	carboxylic ester hydrolase activity
DN409_24175	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DN409_24180	COG0671	phosphoesterase, PA-phosphatase related
DN409_24185	COG0438	transferase activity, transferring glycosyl groups
DN409_24270	COG5002	protein histidine kinase activity
DN409_24275	COG3852	Histidine kinase
DN409_24285	COG2267	carboxylic ester hydrolase activity
DN409_24295	COG1368	sulfuric ester hydrolase activity
DN409_24305	COG4895	conserved protein (DUF2196)
DN409_24320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN409_24325	COG1116	anion transmembrane transporter activity
DN409_24330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN409_24355	COG0494	nUDIX hydrolase
DN409_24400	COG2076	Multidrug Resistance protein
DN409_24405	COG2076	Multidrug Resistance protein
DN409_24410	COG0789	Transcriptional regulator
DN409_24425	COG0288	reversible hydration of carbon dioxide
DN409_24430	COG1271	oxidase subunit
DN409_24435	COG1294	oxidase, subunit
DN409_24455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN409_24475	COG1842	Phage shock protein A
DN409_24500	COG3859	Proton-coupled thiamine transporter YuaJ
DN409_24505	COG5002	protein histidine kinase activity
DN409_24510	COG0745	RESPONSE REGULATOR receiver
DN409_24540	COG1597	lipid kinase activity
DN409_24580	COG0586	Pfam SNARE associated Golgi protein
DN409_24595	COG0577	efflux transmembrane transporter activity
DN409_24600	COG1136	(ABC) transporter
DN409_24605	COG3708	Transcriptional regulator
DN409_24605	COG2207	Transcriptional regulator
DN409_24615	COG1131	(ABC) transporter
DN409_24620	COG5658	integral membrane protein
DN409_24625	COG0640	Transcriptional regulator
DN409_24630	COG0745	RESPONSE REGULATOR receiver
DN409_24635	COG2205	protein histidine kinase activity
DN409_24640	COG0577	efflux transmembrane transporter activity
DN409_24645	COG0577	efflux transmembrane transporter activity
DN409_24650	COG1136	(ABC) transporter
DN409_24655	COG0577	efflux transmembrane transporter activity
DN409_24690	COG3964	amidohydrolase
DN409_24710	COG4948	Mandelate Racemase Muconate Lactonizing
DN409_24720	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DN409_24735	COG1169	isochorismate synthase
DN409_24740	COG1575	Belongs to the MenA family. Type 1 subfamily
DN409_24745	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DN409_24750	COG1278	Cold shock
DN409_24760	COG0789	Transcriptional regulator
DN409_24770	COG0058	SHG alpha-glucan phosphorylase activity
DN409_24780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DN409_24800	COG0039	L-malate dehydrogenase activity
DN409_24940	COG1285	pathogenesis
DN409_24945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DN409_24965	COG2155	Conserved Protein
DN409_24970	COG1098	S1 RNA binding domain
DN409_24975	COG0436	Aminotransferase
DN409_24980	COG1522	sequence-specific DNA binding
DN409_24985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DN409_24990	COG2267	carboxylic ester hydrolase activity
DN409_25000	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DN409_25015	COG5018	Exonuclease
DN409_25020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DN409_25035	COG0423	glycine-tRNA ligase activity
DN409_25040	COG2050	protein possibly involved in aromatic compounds catabolism
DN409_25050	COG1268	BioY protein
DN409_25055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DN409_25060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DN409_25075	COG3584	3D domain protein
DN409_25090	COG1252	NADH dehydrogenase
DN409_25100	COG3708	Transcriptional regulator
DN409_25115	COG1683	Conserved Protein
DN409_25140	COG0316	Belongs to the HesB IscA family
DN409_25155	COG1252	NADH dehydrogenase
DN409_25165	COG0390	transport system, permease component
DN409_25170	COG2824	Alkylphosphonate utilization operon protein PhnA
DN409_25195	COG4837	Protein of unknown function (DUF1462)
DN409_25200	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DN409_25210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DN409_25215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DN409_25235	COG1136	(ABC) transporter
DN409_25235	COG0577	efflux transmembrane transporter activity
DN409_25240	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN409_25250	COG0647	UMP catabolic process
DN409_25260	COG2445	Protein of unknown function DUF86
DN409_25265	COG1494	fructose-1,6-bisphosphatase
DN409_25285	COG4470	Protein conserved in bacteria
DN409_25295	COG0789	Transcriptional regulator
DN409_25300	COG4377	Putative membrane peptidase family (DUF2324)
DN409_25325	COG0739	heme binding
DN409_25335	COG3377	Domain of unknown function (DUF1805)
DN409_25340	COG0737	Belongs to the 5'-nucleotidase family
DN409_25345	COG0719	Fe-S assembly protein
DN409_25350	COG0822	iron-sulfur transferase activity
DN409_25355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DN409_25360	COG0719	Fe-S assembly protein
DN409_25365	COG0396	ATPase activity
DN409_25370	COG1464	Belongs to the NlpA lipoprotein family
DN409_25375	COG1464	Belongs to the NlpA lipoprotein family
DN409_25380	COG2011	ABC-type metal ion transport system permease component
DN409_25395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN409_25400	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DN409_25410	COG1393	Belongs to the ArsC family
DN409_25445	COG1309	transcriptional regulator
DN409_25450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN409_25455	COG1960	acyl-CoA dehydrogenase activity
DN409_25460	COG0183	Belongs to the thiolase family
DN409_25465	COG1250	3-hydroxyacyl-CoA dehydrogenase
DN409_25465	COG1024	Enoyl-CoA hydratase
DN409_25475	COG1686	Belongs to the peptidase S11 family
DN409_25480	COG0506	proline dehydrogenase activity
DN409_25490	COG0011	TIGRFAM Protein of
DN409_25495	COG0840	transmembrane signaling receptor activity
DN409_25510	COG2814	Major facilitator Superfamily
DN409_25515	COG0531	amino acid
DN409_25540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN409_25570	COG0586	Pfam SNARE associated Golgi protein
DN409_25580	COG1376	ErfK ybiS ycfS ynhG family protein
DN409_25585	COG0745	RESPONSE REGULATOR receiver
DN409_25590	COG5002	protein histidine kinase activity
DN409_25610	COG0840	transmembrane signaling receptor activity
DN409_25620	COG2151	metal-sulfur cluster biosynthetic enzyme
DN409_25625	COG3227	Zinc metalloprotease (Elastase)
DN409_25630	COG1741	Belongs to the pirin family
DN409_25645	COG0586	Pfam SNARE associated Golgi protein
DN409_25650	COG0475	glutathione-regulated potassium exporter activity
DN409_25655	COG0490	domain, Protein
DN409_25660	COG1115	amino acid carrier protein
DN409_25665	COG0783	Belongs to the Dps family
DN409_25675	COG2318	DinB family
DN409_25680	COG1611	Belongs to the LOG family
DN409_25690	COG1528	Iron-storage protein
DN409_25695	COG2311	Membrane
DN409_25700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN409_25705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN409_25710	COG1115	amino acid carrier protein
DN409_25715	COG2910	NAD(P)H-binding
DN409_25745	COG0656	L-ascorbic acid biosynthetic process
DN409_25750	COG2814	Major facilitator Superfamily
DN409_25755	COG1733	regulation of RNA biosynthetic process
DN409_25765	COG1252	NADH dehydrogenase
DN409_25785	COG0840	transmembrane signaling receptor activity
DN409_25785	COG3290	protein histidine kinase activity
DN409_25810	COG3655	Transcriptional regulator
DN409_25825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN409_25830	COG3223	Belongs to the PsiE family
DN409_25835	COG1733	regulation of RNA biosynthetic process
DN409_25840	COG0778	Nitroreductase
DN409_25845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN409_25850	COG4224	UPF0291 protein
DN409_25855	COG1522	sequence-specific DNA binding
DN409_25860	COG0288	reversible hydration of carbon dioxide
DN409_25865	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
DN409_25870	COG2233	PERMEase
DN409_25930	COG0557	exoribonuclease II activity
DN409_25935	COG1647	Serine aminopeptidase, S33
DN409_25940	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DN409_25945	COG1346	cytolysis
DN409_25980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DN409_25995	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DN409_26020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DN409_26035	COG2323	membrane
DN409_26050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN409_26060	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DN409_26070	COG1051	belongs to the nudix hydrolase family
DN409_26080	COG0492	ferredoxin-NADP+ reductase activity
DN409_26085	COG0457	Tetratricopeptide repeat
DN409_26090	COG0110	maltose O-acetyltransferase activity
DN409_26110	COG1950	PFAM Membrane protein of
DN409_26120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DN409_26145	COG0789	Transcriptional regulator
DN409_26180	COG0583	DNA-binding transcription factor activity
DN409_26190	COG0655	NAD(P)H dehydrogenase (quinone) activity
DN409_26205	COG1132	(ABC) transporter
DN409_26210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN409_26215	COG3409	Peptidoglycan-binding domain 1 protein
DN409_26215	COG0793	Belongs to the peptidase S41A family
DN409_26220	COG2177	Part of the ABC transporter FtsEX involved in
DN409_26225	COG2884	Cell division ATP-binding protein ftsE
DN409_26260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DN409_26265	COG1278	Cold shock
DN409_26270	COG1040	competence protein
DN409_26275	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DN409_26280	COG0791	NLP P60 protein
DN409_26280	COG1388	LysM domain
DN409_26285	COG1733	regulation of RNA biosynthetic process
DN409_26290	COG1307	EDD domain protein, DegV family
DN409_26295	COG1739	Uncharacterized protein family UPF0029
DN409_26300	COG1316	TRANSCRIPTIONal
DN409_26305	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DN409_26310	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DN409_26315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DN409_26325	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DN409_26325	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DN409_26345	COG1486	melibiose metabolic process
DN409_26350	COG1447	Phosphotransferase system cellobiose-specific component IIA
DN409_26355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DN409_26365	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DN409_26375	COG1447	Phosphotransferase system cellobiose-specific component IIA
DN409_26385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DN409_26390	COG1301	dicarboxylic acid transport
DN409_26405	COG1511	domain protein
DN409_26410	COG0583	DNA-binding transcription factor activity
DN409_26415	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DN409_26420	COG1271	oxidase subunit
DN409_26425	COG1294	oxidase, subunit
DN409_26430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DN409_26440	COG1620	l-lactate permease
DN409_26450	COG2389	metal-binding protein
DN409_26465	COG1368	sulfuric ester hydrolase activity
DN409_26475	COG1388	LysM domain
DN409_26475	COG0791	NLP P60 protein
DN409_26480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN409_26490	COG1215	transferase activity, transferring glycosyl groups
DN409_26495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN409_26505	COG1388	LysM domain
DN409_26505	COG3584	3D domain protein
DN409_26530	COG4715	Zinc finger, swim domain protein
DN409_26535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DN409_26575	COG0577	efflux transmembrane transporter activity
DN409_26580	COG1136	(ABC) transporter
DN409_26620	COG3850	Histidine kinase
DN409_26620	COG5002	protein histidine kinase activity
DN409_26625	COG0745	RESPONSE REGULATOR receiver
DN409_26655	COG0438	transferase activity, transferring glycosyl groups
DN409_26670	COG0438	transferase activity, transferring glycosyl groups
DN409_26675	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DN409_26685	COG1086	Polysaccharide biosynthesis protein
DN409_26695	COG1045	serine acetyltransferase
DN409_26700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DN409_26705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DN409_26710	COG1086	Polysaccharide biosynthesis protein
DN409_26715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DN409_26720	COG4464	protein tyrosine phosphatase activity
DN409_26725	COG0489	protein tyrosine kinase activity
DN409_26730	COG3944	biosynthesis protein
DN409_26735	COG0489	protein tyrosine kinase activity
DN409_26750	COG1609	Transcriptional regulator
DN409_26760	COG0739	heme binding
DN409_26775	COG3279	Response regulator of the LytR AlgR family
DN409_26780	COG2385	sporulation resulting in formation of a cellular spore
DN409_26785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DN409_26795	COG4836	Membrane
DN409_26800	COG1007	ATP synthesis coupled electron transport
DN409_26805	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DN409_26810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DN409_26820	COG0839	Belongs to the complex I subunit 6 family
DN409_26840	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DN409_26855	COG3300	MHYT domain
DN409_26855	COG5001	Diguanylate cyclase
DN409_26905	COG0356	it plays a direct role in the translocation of protons across the membrane
DN409_26940	COG0698	ribose 5-phosphate isomerase
DN409_26950	COG2190	(PTS) system
DN409_26955	COG2259	Doxx family
DN409_26960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DN409_26975	COG0009	L-threonylcarbamoyladenylate synthase
DN409_26990	COG2890	protein-(glutamine-N5) methyltransferase activity
DN409_27015	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DN409_27020	COG1494	fructose-1,6-bisphosphatase
DN409_27040	COG4821	SIS domain
DN409_27050	COG3343	RNA polymerase activity
DN409_27060	COG1960	acyl-CoA dehydrogenase activity
DN409_27065	COG1960	acyl-CoA dehydrogenase activity
DN409_27070	COG1250	3-hydroxyacyl-CoA dehydrogenase
DN409_27075	COG0183	Belongs to the thiolase family
DN409_27080	COG2181	nitrate reductase activity
DN409_27080	COG0247	lactate metabolic process
DN409_27085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN409_27095	COG5001	Diguanylate cyclase
DN409_27095	COG3300	MHYT domain
DN409_27110	COG3227	Zinc metalloprotease (Elastase)
DN409_27115	COG2197	response regulator
DN409_27120	COG4585	Histidine kinase
DN409_27125	COG0842	Transport permease protein
DN409_27130	COG1131	(ABC) transporter
DN409_27135	COG0024	Methionine aminopeptidase
DN409_27145	COG2234	aminopeptidase activity
DN409_27165	COG4506	Protein conserved in bacteria
DN409_27170	COG1619	proteins homologs of microcin C7 resistance protein MccF
DN409_27190	COG0010	Belongs to the arginase family
DN409_27200	COG2814	Major facilitator Superfamily
DN409_27205	COG0789	Transcriptional regulator
DN409_27210	COG0584	glycerophosphoryl diester phosphodiesterase
DN409_27215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN409_27225	COG1994	Peptidase M50
DN409_27235	COG1078	dGTPase activity
DN409_27240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN409_27245	COG1120	ATPase activity
DN409_27250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN409_27255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN409_27275	COG0280	phosphate acetyltransferase
DN409_27290	COG3773	Cell wall hydrolase
DN409_27300	COG2363	Small membrane protein
DN409_27315	COG2233	PERMEase
DN409_27320	COG0561	phosphatase activity
DN409_27325	COG2814	Major facilitator Superfamily
DN409_27335	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DN409_27340	COG1131	(ABC) transporter
DN409_27345	COG2755	lipolytic protein G-D-S-L family
DN409_27350	COG1609	Transcriptional regulator
DN409_27360	COG0460	homoserine dehydrogenase
DN409_27380	COG1011	Hydrolase
DN409_27385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN409_27395	COG2197	response regulator
DN409_27400	COG4585	Histidine kinase
DN409_27400	COG2203	Gaf domain
DN409_27405	COG0351	phosphomethylpyrimidine kinase
DN409_27410	COG3706	GGDEF domain
DN409_27415	COG2879	small protein
DN409_27420	COG1966	Carbon starvation protein
DN409_27425	COG3279	Response regulator of the LytR AlgR family
DN409_27430	COG0477	Major facilitator Superfamily
DN409_27440	COG0297	glycogen (starch) synthase activity
DN409_27455	COG0840	transmembrane signaling receptor activity
DN409_27465	COG1607	acyl-coa hydrolase
DN409_27470	COG1216	Glycosyl transferase, family 2
DN409_27480	COG1216	Glycosyl transferase, family 2
DN409_27490	COG0488	(ABC) transporter
DN409_27495	COG1309	transcriptional regulator
DN409_27500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN409_27505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN409_27505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN409_27510	COG0628	permease
DN409_27525	COG3279	Response regulator of the LytR AlgR family
DN409_27530	COG3275	phosphorelay sensor kinase activity
DN409_27535	COG2814	Major facilitator Superfamily
DN409_27540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN409_27545	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DN409_27555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DN409_27605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DN409_27610	COG1272	protein, Hemolysin III
DN409_27635	COG1164	Oligoendopeptidase f
DN409_27655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN409_27660	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DN409_27665	COG4853	Protein conserved in bacteria
DN409_27675	COG5002	protein histidine kinase activity
DN409_27680	COG0745	RESPONSE REGULATOR receiver
DN409_27710	COG0305	Participates in initiation and elongation during chromosome replication
DN409_27720	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DN409_27725	COG4241	membrane
DN409_27735	COG0629	single-stranded DNA binding
DN409_27745	COG0012	GTP binding
DN409_27750	COG4481	Protein conserved in bacteria
DN409_27755	COG0668	transmembrane transport
DN409_27765	COG1475	DNA binding
DN409_27770	COG1192	Involved in chromosome partitioning
DN409_27795	COG1847	R3H domain protein
DN409_27800	COG0706	membrane insertase activity
DN409_27830	COG5002	protein histidine kinase activity
DN409_27910	COG0778	Nitroreductase
DN409_27950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DN409_27965	COG1674	ftsk spoiiie
DN409_27980	COG0741	lytic transglycosylase activity
DN409_28080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN409_28105	COG0367	asparagine synthase
DN409_28155	COG0739	heme binding
DN409_28210	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DN409_28230	COG2755	lipolytic protein G-D-S-L family
DN409_28230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DN409_28250	COG0756	dUTP diphosphatase activity
DN409_28300	COG0463	Glycosyl transferase, family 2
DN409_28305	COG0463	Glycosyl transferase, family 2
DN409_28310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DN409_28315	COG1086	Polysaccharide biosynthesis protein
DN409_28320	COG1088	dTDP-glucose 4,6-dehydratase activity
DN409_28325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DN409_28330	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DN409_28345	COG2089	acid synthase
DN409_28350	COG4641	Protein conserved in bacteria
DN409_28420	COG0745	RESPONSE REGULATOR receiver
DN409_28425	COG2205	protein histidine kinase activity
DN409_28440	COG1136	(ABC) transporter
DN409_28445	COG0577	efflux transmembrane transporter activity
DN409_28455	COG2002	toxin-antitoxin pair type II binding
DN409_28465	COG1923	regulation of RNA biosynthetic process
DN409_28495	COG2814	Major facilitator Superfamily
DN409_28520	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DN409_28535	COG2002	toxin-antitoxin pair type II binding
DN409_28570	COG0582	viral genome integration into host DNA
DN409_28605	COG1696	Membrane protein involved in D-alanine export
DN409_28615	COG2814	Major facilitator Superfamily
DN409_28635	COG3316	Transposase and inactivated derivatives
DN409_28650	COG3316	Transposase and inactivated derivatives
DN409_28660	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DN409_28685	COG0791	NLP P60 protein
DN409_28685	COG3103	Sh3 type 3 domain protein
DN409_28685	COG1388	LysM domain
DN409_28700	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DN409_28705	COG3316	Transposase and inactivated derivatives
DN409_28710	COG0583	DNA-binding transcription factor activity
DN409_28725	COG4990	cell redox homeostasis
DN409_28730	COG0745	RESPONSE REGULATOR receiver
DN409_28735	COG5002	protein histidine kinase activity
DN409_28740	COG0823	Involved in the tonB-independent uptake of proteins
DN409_28755	COG0745	RESPONSE REGULATOR receiver
DN409_28785	COG0833	amino acid
DN409_28790	COG1285	pathogenesis
DN409_28800	COG2267	carboxylic ester hydrolase activity
DN409_28820	COG0840	transmembrane signaling receptor activity
DN409_28845	COG4977	sequence-specific DNA binding
DN409_28860	COG0083	homoserine kinase activity
DN409_28890	COG4974	Belongs to the 'phage' integrase family
DN409_28900	COG3316	Transposase and inactivated derivatives
DN409_28905	COG1923	regulation of RNA biosynthetic process
DN409_28920	COG2002	toxin-antitoxin pair type II binding
DN409_28925	COG2333	competence protein COMEC
DN409_28925	COG0658	competence protein
DN409_28980	COG2423	ornithine cyclodeaminase activity
DN409_28995	COG0137	argininosuccinate synthase activity
DN409_29015	COG0251	oxidation-reduction process
DN409_29025	COG0736	holo-[acyl-carrier-protein] synthase activity
DN409_29030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DN409_29035	COG1960	acyl-CoA dehydrogenase activity
DN409_29065	COG0039	L-malate dehydrogenase activity
DN409_29085	COG0436	Aminotransferase
DN409_29125	COG0492	ferredoxin-NADP+ reductase activity
DN409_29140	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DN409_29140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DN409_29155	COG1960	acyl-CoA dehydrogenase activity
DN409_29170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DN409_29180	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DN409_29210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DN409_29220	COG0438	transferase activity, transferring glycosyl groups
DN409_29225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN409_29230	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DN409_29245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN409_29255	COG1131	(ABC) transporter
DN409_29270	COG2378	regulation of single-species biofilm formation
DN409_29295	COG3316	Transposase and inactivated derivatives
DN409_29310	COG2002	toxin-antitoxin pair type II binding
DN409_29380	COG2814	Major facilitator Superfamily
DN409_29385	COG0583	DNA-binding transcription factor activity
DN409_29395	COG3316	Transposase and inactivated derivatives
DN409_29475	COG2357	RelA SpoT domain protein
DN409_29480	COG2814	Major facilitator Superfamily
DN409_29490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN409_29500	COG2031	fatty acid transporter
DN409_29560	COG3316	Transposase and inactivated derivatives
DN409_29605	COG3883	PFAM NLP P60 protein
DN409_29605	COG0791	NLP P60 protein
DN409_29690	COG1396	sequence-specific DNA binding
DN409_29720	COG0024	Methionine aminopeptidase
DN409_29855	COG5484	DNA packaging
DN409_30050	COG0419	ATPase involved in DNA repair
DN409_30110	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DN409_30255	COG1674	ftsk spoiiie
DN409_30350	COG3316	Transposase and inactivated derivatives
DN409_30385	COG3011	Protein conserved in bacteria
DN409_30430	COG4974	Belongs to the 'phage' integrase family
DN409_30475	COG3316	Transposase and inactivated derivatives
DN409_30500	COG3316	Transposase and inactivated derivatives
DN409_30520	COG1192	Involved in chromosome partitioning
DN409_30540	COG0484	heat shock protein binding
DN409_30560	COG0741	lytic transglycosylase activity
DN409_30560	COG0791	NLP P60 protein
DN409_30630	COG1674	ftsk spoiiie
DN409_30650	COG1780	Probably involved in ribonucleotide reductase function
DN409_30685	COG3209	COG3209 Rhs family protein
DN409_30710	COG0582	viral genome integration into host DNA
DN409_30770	COG0582	viral genome integration into host DNA