locus-tag	class	description
EXW52_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW52_00010	COG0592	DNA-directed DNA polymerase activity
EXW52_00015	COG2501	S4 domain
EXW52_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW52_00025	COG0187	DNA topoisomerase II activity
EXW52_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW52_00065	COG0516	GMP reductase activity
EXW52_00065	COG0517	IMP dehydrogenase activity
EXW52_00070	COG1686	Belongs to the peptidase S11 family
EXW52_00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW52_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW52_00100	COG1428	Deoxynucleoside kinase
EXW52_00105	COG1428	Deoxynucleoside kinase
EXW52_00110	COG1335	isochorismatase
EXW52_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW52_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW52_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW52_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW52_00180	COG1982	Orn Lys Arg decarboxylase major
EXW52_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW52_00190	COG0470	DNA polymerase III
EXW52_00195	COG1774	PSP1 C-terminal conserved region
EXW52_00200	COG4467	Involved in initiation control of chromosome replication
EXW52_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW52_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW52_00220	COG2002	toxin-antitoxin pair type II binding
EXW52_00230	COG0084	hydrolase, TatD family'
EXW52_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW52_00250	COG4466	Protein conserved in bacteria
EXW52_00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW52_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW52_00270	COG0251	oxidation-reduction process
EXW52_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW52_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW52_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW52_00305	COG2002	toxin-antitoxin pair type II binding
EXW52_00310	COG2244	polysaccharide biosynthetic process
EXW52_00315	COG3956	TIGRFAM MazG family protein
EXW52_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW52_00340	COG1098	S1 RNA binding domain
EXW52_00355	COG2208	phosphoserine phosphatase activity
EXW52_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW52_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW52_00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW52_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW52_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW52_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW52_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW52_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW52_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW52_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW52_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW52_00420	COG1396	sequence-specific DNA binding
EXW52_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW52_00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW52_00520	COG3880	PFAM UvrB UvrC protein
EXW52_00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW52_00530	COG0542	response to heat
EXW52_00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW52_00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW52_00545	COG4956	integral membrane protein (PIN domain superfamily)
EXW52_00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW52_00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW52_00565	COG1045	serine acetyltransferase
EXW52_00570	COG0215	cysteine-tRNA ligase activity
EXW52_00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW52_00585	COG3688	RNA-binding protein containing a PIN domain
EXW52_00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW52_00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW52_00605	COG0250	Participates in transcription elongation, termination and antitermination
EXW52_00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW52_00615	COG0081	regulation of translation
EXW52_00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW52_00625	COG0222	ribosome binding
EXW52_00630	COG2813	Specifically methylates the guanine in position
EXW52_00635	COG0085	RNA polymerase activity
EXW52_00640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW52_00645	COG1358	cellular component organization or biogenesis
EXW52_00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW52_00655	COG0049	tRNA binding
EXW52_00660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW52_00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW52_00670	COG0051	transcription antitermination factor activity, RNA binding
EXW52_00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW52_00680	COG0088	Forms part of the polypeptide exit tunnel
EXW52_00685	COG0089	rRNA binding
EXW52_00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW52_00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW52_00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW52_00710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EXW52_00715	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW52_00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW52_00725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EXW52_00730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW52_00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW52_00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW52_00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW52_00765	COG1841	ribosomal large subunit assembly
EXW52_00770	COG0200	Binds to the 23S rRNA
EXW52_00775	COG0201	protein transport
EXW52_00780	COG0563	adenylate kinase activity
EXW52_00785	COG0024	Methionine aminopeptidase
EXW52_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW52_00800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW52_00805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW52_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW52_00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW52_00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW52_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW52_00860	COG0489	protein tyrosine kinase activity
EXW52_00870	COG2194	sulfuric ester hydrolase activity
EXW52_00875	COG0726	polysaccharide deacetylase
EXW52_00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW52_00960	COG4856	YbbR-like protein
EXW52_00965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW52_00980	COG4946	Tricorn protease homolog
EXW52_00980	COG1506	peptidase
EXW52_00980	COG0823	Involved in the tonB-independent uptake of proteins
EXW52_00995	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_01000	COG2011	ABC-type metal ion transport system permease component
EXW52_01010	COG1464	Belongs to the NlpA lipoprotein family
EXW52_01015	COG0604	alcohol dehydrogenase
EXW52_01025	COG0277	FAD linked oxidase domain protein
EXW52_01030	COG2271	Major facilitator Superfamily
EXW52_01040	COG2814	Major facilitator Superfamily
EXW52_01055	COG0601	transmembrane transport
EXW52_01060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW52_01065	COG0444	Belongs to the ABC transporter superfamily
EXW52_01070	COG4608	Belongs to the ABC transporter superfamily
EXW52_01075	COG4166	transmembrane transport
EXW52_01090	COG4166	transmembrane transport
EXW52_01095	COG4166	transmembrane transport
EXW52_01100	COG0656	L-ascorbic acid biosynthetic process
EXW52_01105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW52_01120	COG4149	molybdate abc transporter
EXW52_01125	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW52_01130	COG1910	domain protein
EXW52_01145	COG0697	spore germination
EXW52_01160	COG0204	Acyl-transferase
EXW52_01170	COG1609	Transcriptional regulator
EXW52_01180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW52_01195	COG5298	Protein conserved in bacteria
EXW52_01220	COG0488	(ABC) transporter
EXW52_01225	COG4585	Histidine kinase
EXW52_01230	COG2197	response regulator
EXW52_01235	COG1131	(ABC) transporter
EXW52_01240	COG1511	domain protein
EXW52_01240	COG0842	Transport permease protein
EXW52_01245	COG0842	Transport permease protein
EXW52_01255	COG0747	negative chemotaxis
EXW52_01265	COG0601	transmembrane transport
EXW52_01270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW52_01275	COG0444	Belongs to the ABC transporter superfamily
EXW52_01280	COG4608	Belongs to the ABC transporter superfamily
EXW52_01285	COG0561	phosphatase activity
EXW52_01315	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW52_01320	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW52_01330	COG0531	amino acid
EXW52_01335	COG2814	Major facilitator Superfamily
EXW52_01345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW52_01355	COG4294	response to UV
EXW52_01360	COG0705	Rhomboid family
EXW52_01365	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW52_01370	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW52_01375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW52_01380	COG0864	Transcriptional regulator
EXW52_01385	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW52_01390	COG2183	response to ionizing radiation
EXW52_01490	COG0802	atpase or kinase
EXW52_01495	COG1214	PFAM Peptidase M22, glycoprotease
EXW52_01500	COG0456	acetyltransferase
EXW52_01510	COG0488	(ABC) transporter
EXW52_01515	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW52_01525	COG1266	CAAX protease self-immunity
EXW52_01530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW52_01535	COG0459	protein refolding
EXW52_01540	COG0519	Catalyzes the synthesis of GMP from XMP
EXW52_01540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW52_01545	COG2252	PERMEase
EXW52_01555	COG5002	protein histidine kinase activity
EXW52_01580	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW52_01610	COG2226	methyltransferase
EXW52_01620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW52_01630	COG1215	transferase activity, transferring glycosyl groups
EXW52_01670	COG2205	protein histidine kinase activity
EXW52_01675	COG0745	RESPONSE REGULATOR receiver
EXW52_01700	COG0697	spore germination
EXW52_01730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW52_01735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW52_01740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW52_01745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW52_01750	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW52_01755	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW52_01760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW52_01765	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW52_01770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW52_01775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW52_01780	COG0138	bifunctional purine biosynthesis protein purh
EXW52_01785	COG0151	Belongs to the GarS family
EXW52_01810	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW52_01815	COG0210	DNA helicase
EXW52_01820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW52_01825	COG4851	CamS sex pheromone cAM373 precursor
EXW52_01835	COG1012	belongs to the aldehyde dehydrogenase family
EXW52_01840	COG1335	isochorismatase
EXW52_01850	COG2011	ABC-type metal ion transport system permease component
EXW52_01870	COG0003	Pfam Anion-transporting ATPase
EXW52_01875	COG1846	Transcriptional regulator
EXW52_01880	COG4682	membrane
EXW52_01890	COG0154	amidase activity
EXW52_01895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW52_01900	COG1597	lipid kinase activity
EXW52_01910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW52_01920	COG1012	belongs to the aldehyde dehydrogenase family
EXW52_01925	COG2076	Multidrug Resistance protein
EXW52_01930	COG2309	aminopeptidase activity
EXW52_01945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW52_01955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW52_01960	COG5002	protein histidine kinase activity
EXW52_01965	COG4807	Protein conserved in bacteria
EXW52_01990	COG1757	Na H antiporter
EXW52_01995	COG1473	amidohydrolase
EXW52_02015	COG0450	alkyl hydroperoxide reductase
EXW52_02025	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW52_02035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW52_02040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW52_02045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW52_02055	COG0492	ferredoxin-NADP+ reductase activity
EXW52_02070	COG0166	Belongs to the GPI family
EXW52_02095	COG5002	protein histidine kinase activity
EXW52_02115	COG3541	Predicted nucleotidyltransferase
EXW52_02120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW52_02120	COG0723	plastoquinol--plastocyanin reductase activity
EXW52_02130	COG0765	amino acid transport
EXW52_02135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW52_02145	COG0840	transmembrane signaling receptor activity
EXW52_02150	COG0277	FAD linked oxidase domain protein
EXW52_02155	COG0366	Alpha amylase catalytic
EXW52_02160	COG1263	PTS System
EXW52_02160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW52_02160	COG2190	(PTS) system
EXW52_02180	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW52_02190	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW52_02205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW52_02210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW52_02215	COG1116	anion transmembrane transporter activity
EXW52_02220	COG0488	(ABC) transporter
EXW52_02265	COG2270	Major facilitator Superfamily
EXW52_02295	COG2310	stress, protein
EXW52_02300	COG2310	stress, protein
EXW52_02305	COG2310	stress, protein
EXW52_02310	COG0861	Integral membrane protein TerC family
EXW52_02320	COG3853	Toxic anion resistance protein (TelA)
EXW52_02330	COG4840	Belongs to the UPF0435 family
EXW52_02335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW52_02345	COG1295	ribonuclease BN
EXW52_02350	COG2217	Heavy metal translocating P-type atpase
EXW52_02355	COG0697	spore germination
EXW52_02380	COG0586	Pfam SNARE associated Golgi protein
EXW52_02395	COG3871	stress protein (general stress protein 26)
EXW52_02400	COG0387	Pfam Sodium calcium exchanger
EXW52_02410	COG0535	radical SAM domain protein
EXW52_02430	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW52_02450	COG3829	transcription factor binding
EXW52_02460	COG0833	amino acid
EXW52_02465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW52_02485	COG2066	Belongs to the glutaminase family
EXW52_02495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW52_02495	COG1263	PTS System
EXW52_02500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW52_02515	COG1216	Glycosyl transferase, family 2
EXW52_02525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW52_02525	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW52_02530	COG0463	Glycosyl transferase, family 2
EXW52_02545	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW52_02550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW52_02565	COG1228	amidohydrolase
EXW52_02570	COG1090	epimerase
EXW52_02575	COG2137	regulation of response to DNA damage stimulus
EXW52_02600	COG1988	membrane-bound metal-dependent
EXW52_02605	COG1194	a g-specific adenine glycosylase
EXW52_02625	COG3557	Belongs to the UPF0374 family
EXW52_02630	COG1132	(ABC) transporter
EXW52_02635	COG4129	membrane
EXW52_02640	COG0067	glutamate synthase
EXW52_02640	COG0069	glutamate synthase activity
EXW52_02640	COG0070	glutamate synthase
EXW52_02645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW52_02650	COG4555	ABC transporter
EXW52_02670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW52_02675	COG0735	belongs to the Fur family
EXW52_02795	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW52_02800	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW52_02820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW52_02830	COG2766	serine protein kinase
EXW52_02835	COG2718	Belongs to the UPF0229 family
EXW52_02850	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW52_02855	COG2268	Band 7 protein
EXW52_02865	COG3290	protein histidine kinase activity
EXW52_02870	COG4565	transcriptional regulatory protein
EXW52_02875	COG2851	Citrate transporter
EXW52_02900	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW52_02905	COG3842	ATPase activity
EXW52_02910	COG1175	transmembrane transport
EXW52_02915	COG0395	ABC-type sugar transport system, permease component
EXW52_02925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW52_02930	COG0745	RESPONSE REGULATOR receiver
EXW52_02935	COG5002	protein histidine kinase activity
EXW52_02945	COG4990	cell redox homeostasis
EXW52_02955	COG3290	protein histidine kinase activity
EXW52_02960	COG4565	transcriptional regulatory protein
EXW52_02965	COG3493	citrate carrier protein
EXW52_02970	COG0281	malic enzyme
EXW52_02980	COG0697	spore germination
EXW52_02985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW52_02995	COG5002	protein histidine kinase activity
EXW52_03000	COG0745	RESPONSE REGULATOR receiver
EXW52_03005	COG0456	acetyltransferase
EXW52_03010	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW52_03015	COG3383	formate dehydrogenase (NAD+) activity
EXW52_03020	COG2427	Protein of unknown function (DUF1641)
EXW52_03035	COG0531	amino acid
EXW52_03045	COG0640	Transcriptional regulator
EXW52_03050	COG2217	Heavy metal translocating P-type atpase
EXW52_03055	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW52_03065	COG3227	Zinc metalloprotease (Elastase)
EXW52_03085	COG2720	vancomycin resistance protein
EXW52_03090	COG1316	TRANSCRIPTIONal
EXW52_03095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW52_03100	COG0346	lactoylglutathione lyase activity
EXW52_03105	COG1253	flavin adenine dinucleotide binding
EXW52_03110	COG1027	Aspartate ammonia-lyase
EXW52_03115	COG1620	l-lactate permease
EXW52_03120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW52_03140	COG3104	oligopeptide transport
EXW52_03145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW52_03150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW52_03155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW52_03175	COG0156	8-amino-7-oxononanoate synthase activity
EXW52_03180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW52_03190	COG4548	von Willebrand factor, type A
EXW52_03195	COG0714	Associated with various cellular activities
EXW52_03215	COG0531	amino acid
EXW52_03220	COG2188	Transcriptional regulator
EXW52_03230	COG1263	PTS System
EXW52_03230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW52_03235	COG0366	Alpha amylase catalytic
EXW52_03250	COG0697	spore germination
EXW52_03255	COG4585	Histidine kinase
EXW52_03260	COG2197	response regulator
EXW52_03265	COG1404	Belongs to the peptidase S8 family
EXW52_03280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW52_03285	COG1115	amino acid carrier protein
EXW52_03290	COG1126	abc transporter atp-binding protein
EXW52_03295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW52_03300	COG0765	amino acid transport
EXW52_03305	COG0765	amino acid transport
EXW52_03310	COG0833	amino acid
EXW52_03340	COG2378	regulation of single-species biofilm formation
EXW52_03345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW52_03350	COG5002	protein histidine kinase activity
EXW52_03365	COG0659	secondary active sulfate transmembrane transporter activity
EXW52_03390	COG0601	transmembrane transport
EXW52_03395	COG4608	Belongs to the ABC transporter superfamily
EXW52_03405	COG2271	Major facilitator Superfamily
EXW52_03410	COG1846	Transcriptional regulator
EXW52_03415	COG0477	Major facilitator Superfamily
EXW52_03420	COG1609	Transcriptional regulator
EXW52_03425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW52_03430	COG1869	D-ribose catabolic process
EXW52_03440	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW52_03445	COG1879	ABC-type sugar transport system periplasmic component
EXW52_03475	COG1063	alcohol dehydrogenase
EXW52_03490	COG3568	Endonuclease Exonuclease Phosphatase
EXW52_03520	COG0840	transmembrane signaling receptor activity
EXW52_03525	COG3584	3D domain protein
EXW52_03525	COG3583	domain protein
EXW52_03530	COG1476	TRANSCRIPTIONal
EXW52_03550	COG3104	oligopeptide transport
EXW52_03555	COG1114	Component of the transport system for branched-chain amino acids
EXW52_03570	COG1113	amino acid transport
EXW52_03575	COG2252	PERMEase
EXW52_03590	COG2153	protein acetylation
EXW52_03600	COG0475	glutathione-regulated potassium exporter activity
EXW52_03600	COG0569	domain protein
EXW52_03615	COG1845	cytochrome c oxidase, subunit III
EXW52_03620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW52_03630	COG0833	amino acid
EXW52_03635	COG4990	cell redox homeostasis
EXW52_03650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW52_03655	COG0697	spore germination
EXW52_03660	COG0531	amino acid
EXW52_03670	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW52_03675	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW52_03685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW52_03690	COG0573	inorganic phosphate transmembrane transporter activity
EXW52_03695	COG0581	inorganic phosphate transmembrane transporter activity
EXW52_03705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW52_03825	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW52_03840	COG3103	Sh3 type 3 domain protein
EXW52_03840	COG4991	sh3 domain protein
EXW52_03840	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW52_03845	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW52_03850	COG1116	anion transmembrane transporter activity
EXW52_03855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW52_03860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW52_03865	COG0352	thiamine-phosphate diphosphorylase activity
EXW52_03870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW52_03875	COG2104	thiamine diphosphate biosynthetic process
EXW52_03880	COG2022	thiamine diphosphate biosynthetic process
EXW52_03885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW52_03890	COG0351	phosphomethylpyrimidine kinase
EXW52_03915	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW52_03920	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW52_03925	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW52_03930	COG2205	protein histidine kinase activity
EXW52_03935	COG2814	Major facilitator Superfamily
EXW52_03940	COG1846	Transcriptional regulator
EXW52_03950	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW52_03955	COG1129	ABC transporter
EXW52_03960	COG1879	ABC-type sugar transport system periplasmic component
EXW52_03965	COG2252	PERMEase
EXW52_03970	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_04030	COG0778	Nitroreductase
EXW52_04035	COG2719	SpoVR family
EXW52_04060	COG1937	Protein conserved in bacteria
EXW52_04065	COG0425	Belongs to the sulfur carrier protein TusA family
EXW52_04065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW52_04070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW52_04070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW52_04075	COG0425	Belongs to the sulfur carrier protein TusA family
EXW52_04080	COG0425	Belongs to the sulfur carrier protein TusA family
EXW52_04080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW52_04085	COG2210	Belongs to the sulfur carrier protein TusA family
EXW52_04090	COG0730	response to heat
EXW52_04100	COG1316	TRANSCRIPTIONal
EXW52_04105	COG0604	alcohol dehydrogenase
EXW52_04110	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW52_04115	COG0604	alcohol dehydrogenase
EXW52_04120	COG2814	Major facilitator Superfamily
EXW52_04135	COG3711	transcriptional antiterminator
EXW52_04135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW52_04140	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW52_04145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW52_04165	COG3584	3D domain protein
EXW52_04165	COG1388	LysM domain
EXW52_04170	COG0577	efflux transmembrane transporter activity
EXW52_04175	COG1136	(ABC) transporter
EXW52_04185	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW52_04200	COG0577	efflux transmembrane transporter activity
EXW52_04205	COG1114	Component of the transport system for branched-chain amino acids
EXW52_04210	COG3546	catalase activity
EXW52_04240	COG0586	Pfam SNARE associated Golgi protein
EXW52_04270	COG0531	amino acid
EXW52_04275	COG0475	glutathione-regulated potassium exporter activity
EXW52_04285	COG1737	Transcriptional regulator
EXW52_04290	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW52_04295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW52_04295	COG1263	PTS System
EXW52_04305	COG2259	Doxx family
EXW52_04325	COG0697	spore germination
EXW52_04330	COG1522	sequence-specific DNA binding
EXW52_04340	COG0300	oxidoreductase activity
EXW52_04355	COG2076	Multidrug Resistance protein
EXW52_04360	COG1309	transcriptional regulator
EXW52_04365	COG2814	Major facilitator Superfamily
EXW52_04370	COG1733	regulation of RNA biosynthetic process
EXW52_04390	COG4533	DNA binding
EXW52_04395	COG2211	Major facilitator Superfamily
EXW52_04405	COG0693	protein deglycase activity
EXW52_04415	COG0531	amino acid
EXW52_04420	COG1012	belongs to the aldehyde dehydrogenase family
EXW52_04435	COG1132	(ABC) transporter
EXW52_04440	COG1132	(ABC) transporter
EXW52_04445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW52_04450	COG0765	amino acid transport
EXW52_04455	COG1126	abc transporter atp-binding protein
EXW52_04470	COG0189	ligase activity
EXW52_04480	COG4399	Belongs to the UPF0754 family
EXW52_04485	COG3679	Belongs to the UPF0342 family
EXW52_04500	COG0028	Belongs to the TPP enzyme family
EXW52_04505	COG3527	Alpha-acetolactate decarboxylase
EXW52_04510	COG0463	Glycosyl transferase, family 2
EXW52_04515	COG1216	Glycosyl transferase, family 2
EXW52_04520	COG2094	Belongs to the DNA glycosylase MPG family
EXW52_04525	COG0561	phosphatase activity
EXW52_04535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW52_04540	COG0318	PFAM AMP-dependent synthetase and ligase
EXW52_04550	COG0586	Pfam SNARE associated Golgi protein
EXW52_04560	COG0789	Transcriptional regulator
EXW52_04560	COG4978	Transcriptional regulator
EXW52_04570	COG0659	secondary active sulfate transmembrane transporter activity
EXW52_04585	COG0653	protein targeting
EXW52_04590	COG2244	polysaccharide biosynthetic process
EXW52_04600	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW52_04605	COG4196	transglutaminase domain protein
EXW52_04630	COG1024	Enoyl-CoA hydratase
EXW52_04645	COG1363	Peptidase, m42
EXW52_04660	COG2318	DinB family
EXW52_04680	COG0579	oxidoreductase
EXW52_04725	COG0601	transmembrane transport
EXW52_04730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW52_04735	COG0444	Belongs to the ABC transporter superfamily
EXW52_04740	COG4608	Belongs to the ABC transporter superfamily
EXW52_04760	COG0477	Major facilitator Superfamily
EXW52_04765	COG3290	protein histidine kinase activity
EXW52_04770	COG4565	transcriptional regulatory protein
EXW52_04775	COG3181	Tripartite tricarboxylate transporter family receptor
EXW52_04805	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EXW52_04855	COG0305	Participates in initiation and elongation during chromosome replication
EXW52_04875	COG1842	Phage shock protein A
EXW52_04885	COG0477	Major facilitator Superfamily
EXW52_04925	COG1183	phosphatidylcholine synthase activity
EXW52_04985	COG2732	(Barnase) inhibitor
EXW52_04990	COG2814	Major facilitator Superfamily
EXW52_04995	COG0640	Transcriptional regulator
EXW52_05020	COG2376	Dihydroxyacetone kinase
EXW52_05040	COG2376	Dihydroxyacetone kinase
EXW52_05050	COG1959	2 iron, 2 sulfur cluster binding
EXW52_05070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW52_05085	COG2720	vancomycin resistance protein
EXW52_05115	COG0076	glutamate decarboxylase activity
EXW52_05140	COG0737	Belongs to the 5'-nucleotidase family
EXW52_05140	COG1525	nuclease
EXW52_05140	COG4085	toxin activity
EXW52_05180	COG0825	malonyl-CoA metabolic process
EXW52_05205	COG2807	transmembrane transport
EXW52_05210	COG2186	Transcriptional regulator
EXW52_05220	COG4585	Histidine kinase
EXW52_05225	COG2197	response regulator
EXW52_05255	COG0420	3'-5' exonuclease activity
EXW52_05260	COG4717	serine-type aminopeptidase activity
EXW52_05265	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW52_05310	COG0346	lactoylglutathione lyase activity
EXW52_05315	COG0346	lactoylglutathione lyase activity
EXW52_05320	COG0457	Tetratricopeptide repeat
EXW52_05330	COG2267	carboxylic ester hydrolase activity
EXW52_05345	COG3620	sequence-specific DNA binding
EXW52_05350	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW52_05355	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW52_05360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW52_05365	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW52_05370	COG1595	DNA-templated transcription, initiation
EXW52_05385	COG3973	AAA domain
EXW52_05390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW52_05405	COG1846	Transcriptional regulator
EXW52_05415	COG0537	adenosine 5'-monophosphoramidase activity
EXW52_05420	COG1131	(ABC) transporter
EXW52_05425	COG4473	ABC transporter
EXW52_05435	COG0247	lactate metabolic process
EXW52_05440	COG1139	Iron-sulfur cluster binding protein
EXW52_05445	COG1556	Lactate utilization protein
EXW52_05460	COG3402	PFAM membrane-flanked domain
EXW52_05465	COG3428	Bacterial PH domain
EXW52_05505	COG3402	PFAM membrane-flanked domain
EXW52_05510	COG3428	Bacterial PH domain
EXW52_05515	COG2329	Antibiotic biosynthesis monooxygenase
EXW52_05520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW52_05525	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW52_05530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW52_05535	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW52_05565	COG1309	transcriptional regulator
EXW52_05570	COG1511	domain protein
EXW52_05605	COG2378	regulation of single-species biofilm formation
EXW52_05610	COG1609	Transcriptional regulator
EXW52_05620	COG1234	tRNA 3'-trailer cleavage
EXW52_05625	COG0095	Lipoate-protein ligase
EXW52_05635	COG0318	PFAM AMP-dependent synthetase and ligase
EXW52_05650	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW52_05660	COG4208	sulfate ABC transporter
EXW52_05705	COG1408	metallophosphoesterase
EXW52_05710	COG1078	dGTPase activity
EXW52_05725	COG1595	DNA-templated transcription, initiation
EXW52_05735	COG3708	Transcriptional regulator
EXW52_05735	COG2207	Transcriptional regulator
EXW52_05740	COG2205	protein histidine kinase activity
EXW52_05745	COG0745	RESPONSE REGULATOR receiver
EXW52_05765	COG0501	Belongs to the peptidase M48B family
EXW52_05770	COG0697	spore germination
EXW52_05800	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW52_05805	COG2224	Isocitrate lyase
EXW52_05815	COG1278	Cold shock
EXW52_05835	COG4903	ComK protein
EXW52_05845	COG0398	Pfam SNARE associated Golgi protein
EXW52_05855	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW52_05860	COG1074	ATP-dependent DNA helicase activity
EXW52_05910	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW52_05935	COG0367	asparagine synthase
EXW52_05945	COG0753	catalase activity
EXW52_05950	COG0004	ammonium transporteR
EXW52_05960	COG1666	GTP binding
EXW52_05965	COG2996	Protein conserved in bacteria
EXW52_05980	COG1329	Transcriptional regulator
EXW52_06015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW52_06025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW52_06040	COG0561	phosphatase activity
EXW52_06060	COG2267	carboxylic ester hydrolase activity
EXW52_06075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW52_06080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW52_06085	COG5504	Zn-dependent protease
EXW52_06100	COG0180	Tryptophanyl-tRNA synthetase
EXW52_06115	COG4166	transmembrane transport
EXW52_06120	COG0601	transmembrane transport
EXW52_06125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW52_06130	COG0444	Belongs to the ABC transporter superfamily
EXW52_06135	COG4608	Belongs to the ABC transporter superfamily
EXW52_06140	COG0534	Mate efflux family protein
EXW52_06145	COG4166	transmembrane transport
EXW52_06165	COG0861	Integral membrane protein TerC family
EXW52_06170	COG4862	establishment of competence for transformation
EXW52_06175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW52_06185	COG1164	Oligoendopeptidase f
EXW52_06195	COG2346	COG2346, Truncated hemoglobins
EXW52_06200	COG4116	CYTH
EXW52_06210	COG2357	RelA SpoT domain protein
EXW52_06220	COG0564	pseudouridine synthase activity
EXW52_06230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW52_06235	COG0772	Belongs to the SEDS family
EXW52_06240	COG1216	Glycosyl transferase, family 2
EXW52_06260	COG0457	Tetratricopeptide repeat
EXW52_06260	COG0463	Glycosyl transferase, family 2
EXW52_06280	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW52_06295	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW52_06340	COG2153	protein acetylation
EXW52_06345	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW52_06350	COG2382	esterase
EXW52_06375	COG5492	domain, Protein
EXW52_06380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW52_06395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW52_06395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW52_06400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW52_06405	COG0134	indole-3-glycerol-phosphate synthase activity
EXW52_06410	COG0135	phosphoribosylanthranilate isomerase activity
EXW52_06415	COG0133	tryptophan synthase activity
EXW52_06420	COG0159	tryptophan synthase activity
EXW52_06430	COG1620	l-lactate permease
EXW52_06435	COG5634	Uncharacterized conserved protein (DUF2278)
EXW52_06475	COG2226	methyltransferase
EXW52_06495	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW52_06500	COG0567	Dehydrogenase, E1 component
EXW52_06505	COG1476	TRANSCRIPTIONal
EXW52_06530	COG4152	abc transporter atp-binding protein
EXW52_06535	COG1668	transmembrane transport
EXW52_06555	COG1686	Belongs to the peptidase S11 family
EXW52_06560	COG0681	Belongs to the peptidase S26 family
EXW52_06595	COG1012	belongs to the aldehyde dehydrogenase family
EXW52_06605	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW52_06610	COG1177	transmembrane transport
EXW52_06615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW52_06625	COG2409	Drug exporters of the RND superfamily
EXW52_06635	COG0564	pseudouridine synthase activity
EXW52_06645	COG2340	Cysteine-rich secretory protein family
EXW52_06650	COG0247	lactate metabolic process
EXW52_06655	COG0277	FAD linked oxidase domain protein
EXW52_06660	COG3835	regulator
EXW52_06670	COG0745	RESPONSE REGULATOR receiver
EXW52_06675	COG5002	protein histidine kinase activity
EXW52_06680	COG2186	Transcriptional regulator
EXW52_06685	COG0247	lactate metabolic process
EXW52_06690	COG1139	Iron-sulfur cluster binding protein
EXW52_06695	COG1556	Lactate utilization protein
EXW52_06700	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW52_06710	COG2116	formate transmembrane transporter activity
EXW52_06715	COG0861	Integral membrane protein TerC family
EXW52_06720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW52_06730	COG2030	dehydratase
EXW52_06750	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_06755	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW52_06765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW52_06780	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW52_06785	COG3842	ATPase activity
EXW52_06795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW52_06800	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW52_06810	COG1349	DNA-binding transcription factor activity
EXW52_06820	COG0235	Class ii aldolase
EXW52_06830	COG2861	carbohydrate metabolic process
EXW52_06840	COG3852	Histidine kinase
EXW52_06845	COG1846	Transcriptional regulator
EXW52_06855	COG2318	DinB family
EXW52_06860	COG5002	protein histidine kinase activity
EXW52_06865	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW52_06870	COG0720	synthase
EXW52_06880	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW52_06885	COG4873	Protein conserved in bacteria
EXW52_06895	COG0456	acetyltransferase
EXW52_06915	COG1780	Probably involved in ribonucleotide reductase function
EXW52_06930	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW52_06935	COG0531	amino acid
EXW52_06940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW52_06955	COG2204	response regulator
EXW52_06960	COG1012	belongs to the aldehyde dehydrogenase family
EXW52_06970	COG1725	Transcriptional regulator
EXW52_06975	COG1131	(ABC) transporter
EXW52_06985	COG1131	(ABC) transporter
EXW52_06990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW52_06995	COG1266	CAAX protease self-immunity
EXW52_07005	COG1522	sequence-specific DNA binding
EXW52_07015	COG1335	isochorismatase
EXW52_07025	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW52_07030	COG2070	2-Nitropropane dioxygenase
EXW52_07035	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW52_07040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW52_07045	COG1696	Membrane protein involved in D-alanine export
EXW52_07050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW52_07065	COG0716	FMN binding
EXW52_07090	COG0534	Mate efflux family protein
EXW52_07110	COG1846	Transcriptional regulator
EXW52_07120	COG1301	dicarboxylic acid transport
EXW52_07125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW52_07135	COG3874	Sporulation protein YtfJ
EXW52_07155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW52_07160	COG0028	Belongs to the TPP enzyme family
EXW52_07165	COG0440	acetolactate synthase activity
EXW52_07175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW52_07185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW52_07195	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW52_07200	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW52_07210	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW52_07215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW52_07220	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW52_07225	COG0107	imidazoleglycerol-phosphate synthase activity
EXW52_07235	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW52_07240	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW52_07255	COG1183	phosphatidylcholine synthase activity
EXW52_07260	COG1368	sulfuric ester hydrolase activity
EXW52_07270	COG0019	diaminopimelate decarboxylase activity
EXW52_07280	COG0175	sulfate reduction
EXW52_07285	COG2046	Belongs to the sulfate adenylyltransferase family
EXW52_07290	COG0529	Catalyzes the synthesis of activated sulfate
EXW52_07295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW52_07315	COG1648	precorrin-2 dehydrogenase activity
EXW52_07320	COG0733	neurotransmitter:sodium symporter activity
EXW52_07340	COG1757	Na H antiporter
EXW52_07360	COG4758	membrane
EXW52_07365	COG4585	Histidine kinase
EXW52_07370	COG2197	response regulator
EXW52_07380	COG1114	Component of the transport system for branched-chain amino acids
EXW52_07390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW52_07435	COG0730	response to heat
EXW52_07440	COG0306	phosphate transporter
EXW52_07445	COG1392	Phosphate transport regulator
EXW52_07450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW52_07465	COG3852	Histidine kinase
EXW52_07470	COG1801	Protein of unknown function DUF72
EXW52_07480	COG0582	viral genome integration into host DNA
EXW52_07485	COG5002	protein histidine kinase activity
EXW52_07500	COG0392	lysyltransferase activity
EXW52_07500	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW52_07515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW52_07520	COG1686	Belongs to the peptidase S11 family
EXW52_07525	COG2715	membrane protein required for spore maturation
EXW52_07530	COG0700	Nucleoside recognition
EXW52_07535	COG1187	pseudouridine synthase activity
EXW52_07545	COG1333	cytochrome c biogenesis protein
EXW52_07550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW52_07555	COG0745	RESPONSE REGULATOR receiver
EXW52_07560	COG5002	protein histidine kinase activity
EXW52_07565	COG2096	Adenosyltransferase
EXW52_07570	COG4942	peptidase
EXW52_07580	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW52_07585	COG1141	Ferredoxin
EXW52_07595	COG4955	Helix-turn-helix domain
EXW52_07600	COG0514	ATP-dependent DNA helicase (RecQ)
EXW52_07605	COG1266	CAAX protease self-immunity
EXW52_07615	COG1408	metallophosphoesterase
EXW52_07630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW52_07650	COG0492	ferredoxin-NADP+ reductase activity
EXW52_07655	COG0252	asparaginase activity
EXW52_07660	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW52_07670	COG1304	FMN binding
EXW52_07700	COG1160	GTP binding
EXW52_07705	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW52_07725	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW52_07735	COG0302	gtp cyclohydrolase
EXW52_07740	COG0142	geranyltranstransferase activity
EXW52_07745	COG2226	methyltransferase
EXW52_07750	COG0142	geranyltranstransferase activity
EXW52_07765	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW52_07775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW52_07780	COG0457	Tetratricopeptide repeat
EXW52_07785	COG5582	Belongs to the UPF0302 family
EXW52_07800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW52_07815	COG4347	Protein of unknown function (DUF1405)
EXW52_07830	COG2738	Putative neutral zinc metallopeptidase
EXW52_07840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW52_07850	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW52_07855	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW52_07860	COG1803	Methylglyoxal synthase
EXW52_07865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW52_07870	COG0438	transferase activity, transferring glycosyl groups
EXW52_07875	COG0617	tRNA 3'-terminal CCA addition
EXW52_07885	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW52_07890	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW52_07900	COG1199	ATP-dependent helicase activity
EXW52_07900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW52_07920	COG3935	DnaD domain protein
EXW52_07925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW52_07935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW52_07935	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW52_07940	COG3331	DNA recombination
EXW52_07975	COG4474	Belongs to the UPF0398 family
EXW52_07980	COG3599	regulation of cell shape
EXW52_07990	COG0116	Belongs to the methyltransferase superfamily
EXW52_08000	COG1199	ATP-dependent helicase activity
EXW52_08005	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW52_08015	COG0024	Methionine aminopeptidase
EXW52_08025	COG2233	PERMEase
EXW52_08030	COG2311	Membrane
EXW52_08035	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW52_08045	COG0456	acetyltransferase
EXW52_08055	COG2897	thiosulfate sulfurtransferase activity
EXW52_08095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW52_08110	COG0454	-acetyltransferase
EXW52_08130	COG0328	RNA-DNA hybrid ribonuclease activity
EXW52_08165	COG3403	YqcI/YcgG family
EXW52_08170	COG1280	lysine exporter protein (LysE YggA)
EXW52_08185	COG3162	membrane
EXW52_08190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW52_08195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW52_08205	COG0475	glutathione-regulated potassium exporter activity
EXW52_08210	COG4978	Transcriptional regulator
EXW52_08210	COG0789	Transcriptional regulator
EXW52_08220	COG2323	membrane
EXW52_08225	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW52_08270	COG1923	regulation of RNA biosynthetic process
EXW52_08280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW52_08285	COG1360	Flagellar Motor Protein
EXW52_08290	COG2201	protein-glutamate methylesterase activity
EXW52_08295	COG0643	Histidine kinase
EXW52_08295	COG2198	Histidine kinase
EXW52_08305	COG1776	CheC inhibitor of MCP methylation
EXW52_08305	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW52_08320	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW52_08340	COG1256	bacterial-type flagellum assembly
EXW52_08345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW52_08365	COG1815	bacterial-type flagellum-dependent cell motility
EXW52_08370	COG1558	bacterial-type flagellum-dependent cell motility
EXW52_08380	COG1766	The M ring may be actively involved in energy transduction
EXW52_08385	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW52_08395	COG1157	protein secretion by the type III secretion system
EXW52_08415	COG1749	Flagellar hook protein flgE
EXW52_08430	COG0784	Response regulator, receiver
EXW52_08430	COG0835	chemotaxis
EXW52_08455	COG0861	Integral membrane protein TerC family
EXW52_08465	COG3383	formate dehydrogenase (NAD+) activity
EXW52_08470	COG2427	Protein of unknown function (DUF1641)
EXW52_08475	COG5609	conserved protein (DUF2294)
EXW52_08480	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW52_08490	COG2116	formate transmembrane transporter activity
EXW52_08495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW52_08500	COG0303	'Molybdopterin
EXW52_08505	COG0314	molybdopterin synthase activity
EXW52_08520	COG0489	protein tyrosine kinase activity
EXW52_08525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW52_08525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW52_08530	COG0741	lytic transglycosylase activity
EXW52_08540	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW52_08545	COG1776	CheC inhibitor of MCP methylation
EXW52_08545	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW52_08555	COG1338	Plays a role in the flagellum-specific transport system
EXW52_08560	COG1987	bacterial-type flagellum assembly
EXW52_08570	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW52_08575	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW52_08580	COG1419	protein localization to endoplasmic reticulum
EXW52_08585	COG4786	Flagellar basal body rod
EXW52_08590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW52_08635	COG2329	Antibiotic biosynthesis monooxygenase
EXW52_08660	COG0583	DNA-binding transcription factor activity
EXW52_08665	COG3842	ATPase activity
EXW52_08715	COG0406	alpha-ribazole phosphatase activity
EXW52_08745	COG0367	asparagine synthase
EXW52_08775	COG1802	Transcriptional regulator
EXW52_08780	COG0697	spore germination
EXW52_08785	COG1216	Glycosyl transferase, family 2
EXW52_08785	COG0438	transferase activity, transferring glycosyl groups
EXW52_08790	COG1757	Na H antiporter
EXW52_08795	COG0789	Transcriptional regulator
EXW52_08800	COG4221	oxidoreductase activity
EXW52_08840	COG0534	Mate efflux family protein
EXW52_08845	COG3340	Belongs to the peptidase S51 family
EXW52_08865	COG0785	Cytochrome C biogenesis protein
EXW52_08870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW52_08885	COG3048	D-serine ammonia-lyase activity
EXW52_08890	COG2733	membrane
EXW52_08930	COG1131	(ABC) transporter
EXW52_08950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW52_08955	COG0528	UMP kinase activity
EXW52_08965	COG1027	Aspartate ammonia-lyase
EXW52_08970	COG0281	malic enzyme
EXW52_08975	COG4191	Histidine kinase
EXW52_08980	COG0784	Response regulator, receiver
EXW52_08985	COG1846	Transcriptional regulator
EXW52_08995	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW52_09010	COG2502	aspartate--ammonia ligase
EXW52_09015	COG3620	sequence-specific DNA binding
EXW52_09065	COG2814	Major facilitator Superfamily
EXW52_09095	COG0477	Major facilitator Superfamily
EXW52_09115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW52_09120	COG2223	nitrite transmembrane transporter activity
EXW52_09125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW52_09140	COG2244	polysaccharide biosynthetic process
EXW52_09145	COG0733	neurotransmitter:sodium symporter activity
EXW52_09155	COG5566	PFAM Mor transcription activator
EXW52_09160	COG2323	membrane
EXW52_09180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW52_09185	COG2132	Multicopper oxidase
EXW52_09195	COG5002	protein histidine kinase activity
EXW52_09200	COG0745	RESPONSE REGULATOR receiver
EXW52_09210	COG0129	dihydroxy-acid dehydratase activity
EXW52_09215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW52_09240	COG2814	Major facilitator Superfamily
EXW52_09245	COG3384	dioxygenase
EXW52_09300	COG4166	transmembrane transport
EXW52_09335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW52_09355	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW52_09360	COG1054	Belongs to the UPF0176 family
EXW52_09370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW52_09375	COG0531	amino acid
EXW52_09410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW52_09425	COG4257	antibiotic catabolic process
EXW52_09430	COG2390	Transcriptional regulator
EXW52_09440	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW52_09445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW52_09450	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW52_09465	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW52_09480	COG0583	DNA-binding transcription factor activity
EXW52_09495	COG0006	proline dipeptidase activity
EXW52_09500	COG2132	Multicopper oxidase
EXW52_09515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW52_09525	COG0583	DNA-binding transcription factor activity
EXW52_09545	COG1114	Component of the transport system for branched-chain amino acids
EXW52_09555	COG1834	amidinotransferase
EXW52_09565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW52_09575	COG2372	response to copper ion
EXW52_09575	COG1276	copper resistance
EXW52_09580	COG4549	nuclear export factor GLE1
EXW52_09590	COG0697	spore germination
EXW52_09595	COG0583	DNA-binding transcription factor activity
EXW52_09600	COG1959	2 iron, 2 sulfur cluster binding
EXW52_09605	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW52_09610	COG0778	Nitroreductase
EXW52_09625	COG0628	permease
EXW52_09640	COG1231	oxidoreductase activity
EXW52_09645	COG0523	cobalamin synthesis protein
EXW52_09655	COG0411	ABC transporter
EXW52_09675	COG0583	DNA-binding transcription factor activity
EXW52_09685	COG1942	4-Oxalocrotonate Tautomerase
EXW52_09700	COG0346	lactoylglutathione lyase activity
EXW52_09710	COG1271	oxidase subunit
EXW52_09715	COG1294	oxidase, subunit
EXW52_09720	COG4988	ABC transporter
EXW52_09725	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW52_09755	COG1686	Belongs to the peptidase S11 family
EXW52_09770	COG1388	LysM domain
EXW52_09770	COG0791	NLP P60 protein
EXW52_09780	COG1132	(ABC) transporter
EXW52_09785	COG0745	RESPONSE REGULATOR receiver
EXW52_09790	COG5002	protein histidine kinase activity
EXW52_09795	COG0300	oxidoreductase activity
EXW52_09800	COG4122	O-methyltransferase activity
EXW52_09815	COG5658	integral membrane protein
EXW52_09830	COG0460	homoserine dehydrogenase
EXW52_09840	COG0083	homoserine kinase activity
EXW52_09855	COG1316	TRANSCRIPTIONal
EXW52_09865	COG0745	RESPONSE REGULATOR receiver
EXW52_09870	COG5002	protein histidine kinase activity
EXW52_09895	COG1285	pathogenesis
EXW52_09900	COG1247	-acetyltransferase
EXW52_09920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW52_09930	COG1082	Xylose isomerase domain protein TIM barrel
EXW52_09940	COG2814	Major facilitator Superfamily
EXW52_09945	COG1279	arginine transmembrane transporter activity
EXW52_09950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW52_09960	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW52_09990	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW52_09995	COG0577	efflux transmembrane transporter activity
EXW52_10000	COG2002	toxin-antitoxin pair type II binding
EXW52_10005	COG1404	Belongs to the peptidase S8 family
EXW52_10010	COG0640	Transcriptional regulator
EXW52_10015	COG0667	Aldo Keto reductase
EXW52_10060	COG3949	Membrane
EXW52_10065	COG0783	Belongs to the Dps family
EXW52_10080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW52_10090	COG1231	oxidoreductase activity
EXW52_10095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW52_10100	COG4989	oxidoreductase activity
EXW52_10105	COG0523	cobalamin synthesis protein
EXW52_10110	COG0456	acetyltransferase
EXW52_10115	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW52_10130	COG1902	pentaerythritol trinitrate reductase activity
EXW52_10135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW52_10145	COG4166	transmembrane transport
EXW52_10150	COG0346	lactoylglutathione lyase activity
EXW52_10160	COG0406	alpha-ribazole phosphatase activity
EXW52_10170	COG5337	Spore coat protein CotH
EXW52_10175	COG1051	belongs to the nudix hydrolase family
EXW52_10180	COG0586	Pfam SNARE associated Golgi protein
EXW52_10185	COG2244	polysaccharide biosynthetic process
EXW52_10195	COG0701	Predicted permease
EXW52_10200	COG3689	TIGRFAM TIGR03943 family protein
EXW52_10205	COG1607	acyl-coa hydrolase
EXW52_10215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW52_10230	COG0702	epimerase
EXW52_10235	COG2839	Protein conserved in bacteria
EXW52_10240	COG1253	flavin adenine dinucleotide binding
EXW52_10265	COG1114	Component of the transport system for branched-chain amino acids
EXW52_10270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW52_10290	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW52_10305	COG1876	peptidase activity
EXW52_10310	COG0494	nUDIX hydrolase
EXW52_10335	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW52_10345	COG0561	phosphatase activity
EXW52_10350	COG1846	Transcriptional regulator
EXW52_10355	COG2814	Major facilitator Superfamily
EXW52_10365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW52_10370	COG4106	trans-aconitate 2-methyltransferase activity
EXW52_10385	COG1819	glycosyl
EXW52_10390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW52_10395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW52_10420	COG0456	acetyltransferase
EXW52_10505	COG3874	Sporulation protein YtfJ
EXW52_10530	COG2226	methyltransferase
EXW52_10570	COG0604	alcohol dehydrogenase
EXW52_10575	COG1595	DNA-templated transcription, initiation
EXW52_10600	COG0426	domain, Protein
EXW52_10600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW52_10610	COG0386	Belongs to the glutathione peroxidase family
EXW52_10615	COG1305	Transglutaminase-like
EXW52_10620	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW52_10625	COG0714	Associated with various cellular activities
EXW52_10630	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW52_10635	COG1140	nitrate reductase beta subunit
EXW52_10640	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW52_10645	COG2181	nitrate reductase activity
EXW52_10650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW52_10655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW52_10660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW52_10665	COG0303	'Molybdopterin
EXW52_10670	COG0314	molybdopterin synthase activity
EXW52_10680	COG2223	nitrite transmembrane transporter activity
EXW52_10700	COG1648	precorrin-2 dehydrogenase activity
EXW52_10710	COG1587	Uroporphyrinogen-III synthase
EXW52_10710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW52_10715	COG2146	nitrite reductase [NAD(P)H] activity
EXW52_10720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW52_10725	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW52_10755	COG2359	stage V sporulation protein S
EXW52_10775	COG5444	nuclease activity
EXW52_10790	COG1418	mRNA catabolic process
EXW52_10795	COG0488	(ABC) transporter
EXW52_10825	COG1413	lyase activity
EXW52_10840	COG2136	Putative SAM-dependent methyltransferase
EXW52_10840	COG2521	methyltransferase
EXW52_10845	COG0018	arginyl-trna synthetase
EXW52_10900	COG0017	Asparaginyl-tRNA synthetase
EXW52_10920	COG1674	ftsk spoiiie
EXW52_10960	COG5444	nuclease activity
EXW52_10995	COG0733	neurotransmitter:sodium symporter activity
EXW52_11025	COG2610	gluconate transmembrane transporter activity
EXW52_11035	COG1794	racemase activity, acting on amino acids and derivatives
EXW52_11045	COG0456	acetyltransferase
EXW52_11050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW52_11055	COG1131	(ABC) transporter
EXW52_11060	COG4473	ABC transporter
EXW52_11070	COG0546	phosphoglycolate phosphatase activity
EXW52_11120	COG0768	penicillin binding
EXW52_11135	COG1272	protein, Hemolysin III
EXW52_11140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW52_11145	COG0805	protein transport
EXW52_11155	COG1307	EDD domain protein, DegV family
EXW52_11160	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW52_11165	COG1999	signal sequence binding
EXW52_11170	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW52_11175	COG0367	asparagine synthase
EXW52_11190	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW52_11195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW52_11200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW52_11255	COG1335	isochorismatase
EXW52_11265	COG0668	transmembrane transport
EXW52_11270	COG2203	Gaf domain
EXW52_11270	COG4585	Histidine kinase
EXW52_11275	COG2197	response regulator
EXW52_11280	COG1737	Transcriptional regulator
EXW52_11285	COG1064	alcohol dehydrogenase
EXW52_11300	COG1070	Carbohydrate kinase
EXW52_11310	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW52_11330	COG0517	IMP dehydrogenase activity
EXW52_11330	COG1125	glycine betaine transport
EXW52_11335	COG1174	glycine betaine transport
EXW52_11370	COG1253	flavin adenine dinucleotide binding
EXW52_11375	COG1012	belongs to the aldehyde dehydrogenase family
EXW52_11380	COG5506	Protein of unknown function (DUF1694)
EXW52_11395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW52_11400	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW52_11405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW52_11410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW52_11415	COG0456	acetyltransferase
EXW52_11420	COG3829	transcription factor binding
EXW52_11425	COG1509	lysine 2,3-aminomutase activity
EXW52_11435	COG4479	Belongs to the UPF0346 family
EXW52_11460	COG0515	serine threonine protein kinase
EXW52_11460	COG4991	sh3 domain protein
EXW52_11460	COG3064	Membrane
EXW52_11470	COG0671	phosphoesterase, PA-phosphatase related
EXW52_11475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW52_11480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW52_11560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW52_11585	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_11605	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW52_11605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW52_11615	COG2814	Major facilitator Superfamily
EXW52_11625	COG0372	Belongs to the citrate synthase family
EXW52_11630	COG2079	MmgE PrpD family protein
EXW52_11635	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW52_11640	COG1960	acyl-CoA dehydrogenase activity
EXW52_11645	COG2084	Dehydrogenase
EXW52_11650	COG1012	belongs to the aldehyde dehydrogenase family
EXW52_11655	COG1280	lysine exporter protein (LysE YggA)
EXW52_11660	COG1024	Enoyl-CoA hydratase
EXW52_11675	COG0420	3'-5' exonuclease activity
EXW52_11695	COG2223	nitrite transmembrane transporter activity
EXW52_11700	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_11705	COG1169	isochorismate synthase
EXW52_11710	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW52_11715	COG3433	isochorismatase activity
EXW52_11715	COG1535	isochorismatase
EXW52_11720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW52_11725	COG3251	PFAM MbtH domain protein
EXW52_11730	COG2814	Major facilitator Superfamily
EXW52_11745	COG0776	regulation of translation
EXW52_11755	COG2318	DinB family
EXW52_11760	COG1115	amino acid carrier protein
EXW52_11775	COG2329	Antibiotic biosynthesis monooxygenase
EXW52_11790	COG1187	pseudouridine synthase activity
EXW52_11795	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW52_11800	COG3655	Transcriptional regulator
EXW52_11810	COG1136	(ABC) transporter
EXW52_11820	COG2814	Major facilitator Superfamily
EXW52_11835	COG0028	Belongs to the TPP enzyme family
EXW52_11860	COG1253	flavin adenine dinucleotide binding
EXW52_11895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW52_11915	COG1846	Transcriptional regulator
EXW52_11930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW52_11935	COG1309	transcriptional regulator
EXW52_11965	COG1247	-acetyltransferase
EXW52_12005	COG0596	Alpha beta hydrolase
EXW52_12010	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW52_12020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW52_12050	COG0583	DNA-binding transcription factor activity
EXW52_12055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW52_12115	COG0583	DNA-binding transcription factor activity
EXW52_12120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW52_12125	COG2258	MOSC domain
EXW52_12140	COG1132	(ABC) transporter
EXW52_12145	COG1132	(ABC) transporter
EXW52_12165	COG1396	sequence-specific DNA binding
EXW52_12200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW52_12210	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW52_12215	COG1595	DNA-templated transcription, initiation
EXW52_12235	COG1649	PFAM Uncharacterised BCR, COG1649
EXW52_12255	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW52_12260	COG2971	BadF BadG BcrA BcrD
EXW52_12270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW52_12325	COG0500	methyltransferase
EXW52_12325	COG3615	Tellurite resistance protein tehB
EXW52_12335	COG0693	protein deglycase activity
EXW52_12345	COG0588	phosphoglycerate mutase activity
EXW52_12385	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW52_12390	COG0110	maltose O-acetyltransferase activity
EXW52_12405	COG1136	(ABC) transporter
EXW52_12435	COG1686	Belongs to the peptidase S11 family
EXW52_12460	COG0768	penicillin binding
EXW52_12465	COG0745	RESPONSE REGULATOR receiver
EXW52_12470	COG2205	protein histidine kinase activity
EXW52_12475	COG1136	(ABC) transporter
EXW52_12480	COG0577	efflux transmembrane transporter activity
EXW52_12490	COG1595	DNA-templated transcription, initiation
EXW52_12500	COG0768	penicillin binding
EXW52_12505	COG0768	penicillin binding
EXW52_12540	COG1252	NADH dehydrogenase
EXW52_12545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW52_12545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW52_12560	COG0697	spore germination
EXW52_12590	COG3397	chitin binding
EXW52_12595	COG0823	Involved in the tonB-independent uptake of proteins
EXW52_12605	COG1408	metallophosphoesterase
EXW52_12615	COG1131	(ABC) transporter
EXW52_12625	COG1309	transcriptional regulator
EXW52_12635	COG1960	acyl-CoA dehydrogenase activity
EXW52_12640	COG0439	Biotin carboxylase
EXW52_12645	COG0511	ligase activity, forming carbon-carbon bonds
EXW52_12650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW52_12655	COG1024	Enoyl-CoA hydratase
EXW52_12660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW52_12665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW52_12705	COG0572	uridine kinase
EXW52_12740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW52_12770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW52_12795	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_12800	COG1733	regulation of RNA biosynthetic process
EXW52_12825	COG1309	transcriptional regulator
EXW52_12840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW52_12855	COG0697	spore germination
EXW52_12860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW52_12885	COG1063	alcohol dehydrogenase
EXW52_12895	COG2323	membrane
EXW52_12910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW52_12915	COG0697	spore germination
EXW52_12935	COG0201	protein transport
EXW52_12945	COG0737	Belongs to the 5'-nucleotidase family
EXW52_12950	COG3227	Zinc metalloprotease (Elastase)
EXW52_12955	COG1523	belongs to the glycosyl hydrolase 13 family
EXW52_12970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW52_12975	COG1073	alpha beta
EXW52_12985	COG0577	efflux transmembrane transporter activity
EXW52_12990	COG1136	(ABC) transporter
EXW52_13020	COG5002	protein histidine kinase activity
EXW52_13025	COG0745	RESPONSE REGULATOR receiver
EXW52_13030	COG1011	Hydrolase
EXW52_13055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW52_13060	COG1183	phosphatidylcholine synthase activity
EXW52_13075	COG1132	(ABC) transporter
EXW52_13085	COG3961	Belongs to the TPP enzyme family
EXW52_13105	COG0322	excinuclease ABC activity
EXW52_13130	COG2318	DinB family
EXW52_13145	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW52_13170	COG3878	Protein conserved in bacteria
EXW52_13195	COG1051	belongs to the nudix hydrolase family
EXW52_13200	COG0592	DNA-directed DNA polymerase activity
EXW52_13205	COG2816	NAD+ diphosphatase activity
EXW52_13215	COG2223	nitrite transmembrane transporter activity
EXW52_13220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW52_13250	COG0697	spore germination
EXW52_13255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW52_13270	COG0584	glycerophosphoryl diester phosphodiesterase
EXW52_13285	COG1733	regulation of RNA biosynthetic process
EXW52_13295	COG2814	Major facilitator Superfamily
EXW52_13310	COG1132	(ABC) transporter
EXW52_13310	COG2375	cellular response to nickel ion
EXW52_13315	COG1132	(ABC) transporter
EXW52_13345	COG0768	penicillin binding
EXW52_13350	COG0671	phosphoesterase, PA-phosphatase related
EXW52_13355	COG0604	alcohol dehydrogenase
EXW52_13360	COG5002	protein histidine kinase activity
EXW52_13365	COG0745	RESPONSE REGULATOR receiver
EXW52_13375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW52_13385	COG2205	protein histidine kinase activity
EXW52_13400	COG1122	ATPase activity
EXW52_13405	COG4720	Psort location CytoplasmicMembrane, score
EXW52_13410	COG1794	racemase activity, acting on amino acids and derivatives
EXW52_13415	COG1819	glycosyl
EXW52_13425	COG0768	penicillin binding
EXW52_13430	COG5002	protein histidine kinase activity
EXW52_13435	COG0561	phosphatase activity
EXW52_13485	COG2124	cytochrome p450
EXW52_13535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW52_13545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW52_13550	COG0460	homoserine dehydrogenase
EXW52_13570	COG0577	efflux transmembrane transporter activity
EXW52_13575	COG1136	(ABC) transporter
EXW52_13590	COG0488	(ABC) transporter
EXW52_13595	COG0667	Aldo Keto reductase
EXW52_13600	COG0583	DNA-binding transcription factor activity
EXW52_13625	COG2205	protein histidine kinase activity
EXW52_13630	COG0745	RESPONSE REGULATOR receiver
EXW52_13645	COG3773	Cell wall hydrolase
EXW52_13650	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW52_13660	COG3386	PFAM SMP-30 Gluconolaconase
EXW52_13715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW52_13730	COG2959	enzyme of heme biosynthesis
EXW52_13760	COG3483	tryptophan 2,3-dioxygenase activity
EXW52_13765	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW52_13770	COG3844	kynureninase activity
EXW52_13775	COG1309	transcriptional regulator
EXW52_13790	COG3284	Transcriptional regulator
EXW52_13805	COG1349	DNA-binding transcription factor activity
EXW52_13825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW52_13830	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW52_13835	COG0022	dehydrogenase e1 component
EXW52_13840	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW52_13850	COG2223	nitrite transmembrane transporter activity
EXW52_13860	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_13865	COG0456	acetyltransferase
EXW52_13865	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW52_13900	COG4176	ABC-type proline glycine betaine transport system permease component
EXW52_13905	COG4175	Glycine betaine
EXW52_13905	COG0517	IMP dehydrogenase activity
EXW52_13930	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW52_13935	COG2153	protein acetylation
EXW52_13940	COG3397	chitin binding
EXW52_13950	COG1819	glycosyl
EXW52_13965	COG2205	protein histidine kinase activity
EXW52_13970	COG2315	Protein conserved in bacteria
EXW52_14015	COG3973	AAA domain
EXW52_14030	COG2105	PFAM AIG2 family protein
EXW52_14035	COG0514	ATP-dependent DNA helicase (RecQ)
EXW52_14055	COG4637	Psort location Cytoplasmic, score
EXW52_14075	COG1227	inorganic diphosphatase activity
EXW52_14080	COG3397	chitin binding
EXW52_14085	COG2318	DinB family
EXW52_14100	COG1162	GTPase activity
EXW52_14105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW52_14110	COG1115	amino acid carrier protein
EXW52_14115	COG1012	belongs to the aldehyde dehydrogenase family
EXW52_14120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW52_14130	COG3938	Belongs to the proline racemase family
EXW52_14135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW52_14185	COG1078	dGTPase activity
EXW52_14190	COG0586	Pfam SNARE associated Golgi protein
EXW52_14205	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW52_14210	COG4166	transmembrane transport
EXW52_14220	COG4948	Mandelate Racemase Muconate Lactonizing
EXW52_14240	COG0667	Aldo Keto reductase
EXW52_14290	COG2936	dipeptidyl-peptidase activity
EXW52_14300	COG0745	RESPONSE REGULATOR receiver
EXW52_14320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW52_14325	COG1164	Oligoendopeptidase f
EXW52_14345	COG1307	EDD domain protein, DegV family
EXW52_14375	COG1335	isochorismatase
EXW52_14390	COG2814	Major facilitator Superfamily
EXW52_14400	COG1664	Polymer-forming cytoskeletal
EXW52_14405	COG0789	Transcriptional regulator
EXW52_14410	COG4533	DNA binding
EXW52_14415	COG0477	Major facilitator Superfamily
EXW52_14415	COG2814	Major facilitator Superfamily
EXW52_14430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW52_14435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW52_14440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW52_14445	COG0438	transferase activity, transferring glycosyl groups
EXW52_14450	COG3328	transposase activity
EXW52_14470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW52_14475	COG0438	transferase activity, transferring glycosyl groups
EXW52_14480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW52_14500	COG2261	transglycosylase associated protein
EXW52_14515	COG2226	methyltransferase
EXW52_14550	COG0436	Aminotransferase
EXW52_14555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW52_14580	COG1131	(ABC) transporter
EXW52_14585	COG2188	Transcriptional regulator
EXW52_14625	COG0628	permease
EXW52_14655	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW52_14665	COG0697	spore germination
EXW52_14690	COG4912	Dna alkylation repair
EXW52_14715	COG2814	Major facilitator Superfamily
EXW52_14720	COG1368	sulfuric ester hydrolase activity
EXW52_14735	COG0488	(ABC) transporter
EXW52_14740	COG1033	growth of symbiont in host cell
EXW52_14740	COG2409	Drug exporters of the RND superfamily
EXW52_14750	COG1309	transcriptional regulator
EXW52_14770	COG0287	Prephenate dehydrogenase
EXW52_14785	COG1605	Chorismate mutase
EXW52_14785	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW52_14815	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EXW52_14830	COG1388	LysM domain
EXW52_14830	COG3584	3D domain protein
EXW52_14840	COG0346	lactoylglutathione lyase activity
EXW52_14850	COG0431	NADPH-dependent FMN reductase
EXW52_14855	COG2610	gluconate transmembrane transporter activity
EXW52_14860	COG1024	Enoyl-CoA hydratase
EXW52_14870	COG3829	transcription factor binding
EXW52_14870	COG3290	protein histidine kinase activity
EXW52_14880	COG0579	oxidoreductase
EXW52_14885	COG1879	ABC-type sugar transport system periplasmic component
EXW52_14900	COG1129	ABC transporter
EXW52_14905	COG2390	Transcriptional regulator
EXW52_14920	COG1830	Aldolase
EXW52_14925	COG2226	methyltransferase
EXW52_14940	COG0346	lactoylglutathione lyase activity
EXW52_14945	COG2329	Antibiotic biosynthesis monooxygenase
EXW52_14965	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW52_14970	COG2207	Transcriptional regulator
EXW52_14980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW52_14985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW52_14990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW52_14995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW52_15000	COG3239	Fatty acid desaturase
EXW52_15020	COG3655	Transcriptional regulator
EXW52_15065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW52_15070	COG0346	lactoylglutathione lyase activity
EXW52_15100	COG0714	Associated with various cellular activities
EXW52_15120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW52_15125	COG0753	catalase activity
EXW52_15135	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW52_15155	COG0778	Nitroreductase
EXW52_15160	COG1846	Transcriptional regulator
EXW52_15200	COG1725	Transcriptional regulator
EXW52_15235	COG2207	Transcriptional regulator
EXW52_15240	COG0456	acetyltransferase
EXW52_15255	COG0697	spore germination
EXW52_15260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW52_15270	COG1671	Belongs to the UPF0178 family
EXW52_15285	COG0642	Histidine kinase
EXW52_15290	COG0745	RESPONSE REGULATOR receiver
EXW52_15295	COG0596	Alpha beta hydrolase
EXW52_15305	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW52_15305	COG0456	acetyltransferase
EXW52_15330	COG0730	response to heat
EXW52_15340	COG0833	amino acid
EXW52_15350	COG4335	DNA alkylation repair
EXW52_15390	COG0768	penicillin binding
EXW52_15400	COG3104	oligopeptide transport
EXW52_15405	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW52_15420	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW52_15425	COG1984	allophanate hydrolase subunit 2
EXW52_15430	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW52_15435	COG1414	Transcriptional regulator
EXW52_15455	COG1960	acyl-CoA dehydrogenase activity
EXW52_15480	COG0640	Transcriptional regulator
EXW52_15490	COG3314	Sporulation integral membrane protein YlbJ
EXW52_15510	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW52_15525	COG0574	Belongs to the PEP-utilizing enzyme family
EXW52_15525	COG3848	Pyruvate phosphate dikinase
EXW52_15535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW52_15545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW52_15560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW52_15585	COG1131	(ABC) transporter
EXW52_15605	COG1073	alpha beta
EXW52_15630	COG5002	protein histidine kinase activity
EXW52_15635	COG0745	RESPONSE REGULATOR receiver
EXW52_15645	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW52_15665	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW52_15670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW52_15675	COG1121	(ABC) transporter
EXW52_15690	COG1999	signal sequence binding
EXW52_15695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW52_15700	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW52_15725	COG0798	PFAM Bile acid sodium symporter
EXW52_15730	COG0346	lactoylglutathione lyase activity
EXW52_15735	COG0640	Transcriptional regulator
EXW52_15745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW52_15745	COG3320	Male sterility
EXW52_15750	COG1309	transcriptional regulator
EXW52_15755	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_15760	COG1522	sequence-specific DNA binding
EXW52_15775	COG0346	lactoylglutathione lyase activity
EXW52_15805	COG2226	methyltransferase
EXW52_15815	COG2814	Major facilitator Superfamily
EXW52_15845	COG0745	RESPONSE REGULATOR receiver
EXW52_15850	COG5002	protein histidine kinase activity
EXW52_15850	COG3850	Histidine kinase
EXW52_15880	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW52_15895	COG2309	aminopeptidase activity
EXW52_15905	COG1690	Belongs to the RtcB family
EXW52_15920	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW52_15940	COG1136	(ABC) transporter
EXW52_15945	COG0577	efflux transmembrane transporter activity
EXW52_15965	COG3850	Histidine kinase
EXW52_15965	COG5002	protein histidine kinase activity
EXW52_15980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW52_16010	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW52_16030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW52_16055	COG5444	nuclease activity
EXW52_16105	COG2814	Major facilitator Superfamily
EXW52_16150	COG1876	peptidase activity
EXW52_16155	COG2843	Capsule synthesis protein
EXW52_16170	COG0477	Major facilitator Superfamily
EXW52_16185	COG1846	Transcriptional regulator
EXW52_16190	COG2814	Major facilitator Superfamily
EXW52_16210	COG2211	Major facilitator Superfamily
EXW52_16270	COG0789	Transcriptional regulator
EXW52_16305	COG1476	TRANSCRIPTIONal
EXW52_16320	COG1288	antiporter activity
EXW52_16325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW52_16370	COG3718	enzyme involved in inositol metabolism
EXW52_16400	COG0673	inositol 2-dehydrogenase activity
EXW52_16405	COG2814	Major facilitator Superfamily
EXW52_16410	COG1609	Transcriptional regulator
EXW52_16440	COG1073	alpha beta
EXW52_16495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW52_16505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW52_16555	COG4187	Peptidase family M20/M25/M40
EXW52_16575	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW52_16580	COG2031	fatty acid transporter
EXW52_16590	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW52_16630	COG1122	ATPase activity
EXW52_16655	COG1288	antiporter activity
EXW52_16660	COG2356	endonuclease I
EXW52_16665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW52_16685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW52_16705	COG1785	Belongs to the alkaline phosphatase family
EXW52_16710	COG0778	Nitroreductase
EXW52_16715	COG1733	regulation of RNA biosynthetic process
EXW52_16730	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_16740	COG1131	(ABC) transporter
EXW52_16770	COG1595	DNA-templated transcription, initiation
EXW52_16785	COG1011	Hydrolase
EXW52_16790	COG2365	Tyrosine phosphatase family
EXW52_16810	COG0346	lactoylglutathione lyase activity
EXW52_16815	COG1940	carbohydrate kinase activity
EXW52_16820	COG0738	Major facilitator superfamily
EXW52_16825	COG0110	maltose O-acetyltransferase activity
EXW52_16840	COG0628	permease
EXW52_16845	COG2261	transglycosylase associated protein
EXW52_16880	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW52_16890	COG1253	flavin adenine dinucleotide binding
EXW52_16895	COG0789	Transcriptional regulator
EXW52_16900	COG0697	spore germination
EXW52_16910	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW52_16915	COG3813	Protein conserved in bacteria
EXW52_16920	COG2706	6-phosphogluconolactonase activity
EXW52_16925	COG1070	Carbohydrate kinase
EXW52_16935	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW52_16940	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW52_16945	COG4702	Belongs to the UPF0303 family
EXW52_16955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW52_16975	COG0384	phenazine biosynthesis protein PhzF
EXW52_16995	COG0318	PFAM AMP-dependent synthetase and ligase
EXW52_17000	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW52_17005	COG1733	regulation of RNA biosynthetic process
EXW52_17025	COG1191	sigma factor activity
EXW52_17050	COG1876	peptidase activity
EXW52_17075	COG0741	lytic transglycosylase activity
EXW52_17140	COG1522	sequence-specific DNA binding
EXW52_17145	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW52_17150	COG0657	acetylesterase activity
EXW52_17160	COG2814	Major facilitator Superfamily
EXW52_17165	COG1309	transcriptional regulator
EXW52_17185	COG2224	Isocitrate lyase
EXW52_17215	COG0814	amino acid
EXW52_17245	COG1151	hydroxylamine reductase activity
EXW52_17275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW52_17285	COG2072	flavoprotein involved in K transport
EXW52_17325	COG0604	alcohol dehydrogenase
EXW52_17330	COG1113	amino acid transport
EXW52_17340	COG2814	Major facilitator Superfamily
EXW52_17355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW52_17360	COG1012	belongs to the aldehyde dehydrogenase family
EXW52_17370	COG0534	Mate efflux family protein
EXW52_17375	COG1012	belongs to the aldehyde dehydrogenase family
EXW52_17380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW52_17395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW52_17400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW52_17420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW52_17425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW52_17430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW52_17435	COG3739	integral membrane protein
EXW52_17460	COG0583	DNA-binding transcription factor activity
EXW52_17480	COG1193	negative regulation of DNA recombination
EXW52_17500	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW52_17505	COG1164	Oligoendopeptidase f
EXW52_17530	COG3781	membrane
EXW52_17545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW52_17600	COG0640	Transcriptional regulator
EXW52_17605	COG0604	alcohol dehydrogenase
EXW52_17610	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW52_17615	COG0457	Tetratricopeptide repeat
EXW52_17625	COG2808	Putative FMN-binding domain
EXW52_17630	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW52_17640	COG0277	FAD linked oxidase domain protein
EXW52_17660	COG1285	pathogenesis
EXW52_17670	COG2514	catechol 2,3-dioxygenase activity
EXW52_17675	COG2720	vancomycin resistance protein
EXW52_17700	COG1278	Cold shock
EXW52_17710	COG0716	FMN binding
EXW52_17720	COG0494	nUDIX hydrolase
EXW52_17740	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_17750	COG0165	Argininosuccinate lyase
EXW52_17765	COG4145	pantothenate transmembrane transporter activity
EXW52_17775	COG1012	belongs to the aldehyde dehydrogenase family
EXW52_17780	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_17790	COG1657	PFAM Prenyltransferase squalene oxidase
EXW52_17795	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW52_17800	COG2962	Rard protein
EXW52_17805	COG3326	Membrane
EXW52_17810	COG0531	amino acid
EXW52_17845	COG2226	methyltransferase
EXW52_17850	COG4166	transmembrane transport
EXW52_17855	COG4166	transmembrane transport
EXW52_17860	COG4166	transmembrane transport
EXW52_17875	COG1595	DNA-templated transcription, initiation
EXW52_17885	COG1131	(ABC) transporter
EXW52_17905	COG0673	inositol 2-dehydrogenase activity
EXW52_17910	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW52_17915	COG0187	DNA topoisomerase II activity
EXW52_17920	COG1832	CoA-binding protein
EXW52_17925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW52_17930	COG0745	RESPONSE REGULATOR receiver
EXW52_17940	COG1328	CTP reductase activity
EXW52_17940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW52_17950	COG4841	protein insertion into membrane
EXW52_17955	COG0824	Thioesterase
EXW52_17975	COG2176	DNA-directed DNA polymerase activity
EXW52_17980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW52_18000	COG1132	(ABC) transporter
EXW52_18005	COG1266	CAAX protease self-immunity
EXW52_18010	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW52_18040	COG2211	Major facilitator Superfamily
EXW52_18050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW52_18065	COG0183	Belongs to the thiolase family
EXW52_18070	COG0318	PFAM AMP-dependent synthetase and ligase
EXW52_18075	COG1268	BioY protein
EXW52_18080	COG0318	PFAM AMP-dependent synthetase and ligase
EXW52_18085	COG1396	sequence-specific DNA binding
EXW52_18130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW52_18145	COG5002	protein histidine kinase activity
EXW52_18155	COG0400	carboxylic ester hydrolase activity
EXW52_18160	COG0346	lactoylglutathione lyase activity
EXW52_18165	COG0069	glutamate synthase activity
EXW52_18170	COG1902	pentaerythritol trinitrate reductase activity
EXW52_18180	COG1329	Transcriptional regulator
EXW52_18185	COG0010	Belongs to the arginase family
EXW52_18195	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW52_18200	COG2986	histidine ammonia-lyase
EXW52_18210	COG2226	methyltransferase
EXW52_18240	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW52_18245	COG0785	Cytochrome C biogenesis protein
EXW52_18260	COG1473	amidohydrolase
EXW52_18265	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW52_18270	COG1131	(ABC) transporter
EXW52_18280	COG0583	DNA-binding transcription factor activity
EXW52_18290	COG1346	cytolysis
EXW52_18305	COG0730	response to heat
EXW52_18315	COG3409	Peptidoglycan-binding domain 1 protein
EXW52_18315	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW52_18335	COG1132	(ABC) transporter
EXW52_18340	COG1132	(ABC) transporter
EXW52_18345	COG3763	UPF0154 protein
EXW52_18365	COG3639	organic phosphonate transmembrane transporter activity
EXW52_18375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW52_18380	COG0737	Belongs to the 5'-nucleotidase family
EXW52_18390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW52_18395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW52_18410	COG1695	Transcriptional regulator
EXW52_18415	COG1132	(ABC) transporter
EXW52_18450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW52_18460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW52_18470	COG3420	alginic acid biosynthetic process
EXW52_18470	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW52_18480	COG1442	glycosyl transferase family 8
EXW52_18485	COG1216	Glycosyl transferase, family 2
EXW52_18485	COG1442	glycosyl transferase family 8
EXW52_18500	COG0297	glycogen (starch) synthase activity
EXW52_18510	COG0438	transferase activity, transferring glycosyl groups
EXW52_18520	COG1215	transferase activity, transferring glycosyl groups
EXW52_18525	COG0438	transferase activity, transferring glycosyl groups
EXW52_18530	COG0438	transferase activity, transferring glycosyl groups
EXW52_18535	COG1086	Polysaccharide biosynthesis protein
EXW52_18540	COG0489	protein tyrosine kinase activity
EXW52_18545	COG3944	biosynthesis protein
EXW52_18550	COG0174	glutamine synthetase
EXW52_18555	COG0789	Transcriptional regulator
EXW52_18560	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW52_18565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW52_18570	COG2860	membrane
EXW52_18575	COG0464	growth
EXW52_18595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW52_18605	COG3584	3D domain protein
EXW52_18605	COG1388	LysM domain
EXW52_18610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW52_18610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW52_18610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW52_18615	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW52_18620	COG1349	DNA-binding transcription factor activity
EXW52_18625	COG1979	alcohol dehydrogenase
EXW52_18630	COG2322	membrane
EXW52_18640	COG1113	amino acid transport
EXW52_18655	COG1473	amidohydrolase
EXW52_18660	COG1408	metallophosphoesterase
EXW52_18665	COG2116	formate transmembrane transporter activity
EXW52_18680	COG2217	Heavy metal translocating P-type atpase
EXW52_18685	COG2608	mercury ion transmembrane transporter activity
EXW52_18690	COG1937	Protein conserved in bacteria
EXW52_18710	COG2819	hydrolase of the alpha beta superfamily
EXW52_18715	COG1120	ATPase activity
EXW52_18720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW52_18725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW52_18730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW52_18735	COG0708	Exodeoxyribonuclease III
EXW52_18740	COG2169	Transcriptional regulator
EXW52_18745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW52_18750	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW52_18755	COG2706	6-phosphogluconolactonase activity
EXW52_18760	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW52_18765	COG2364	Membrane
EXW52_18775	COG0346	lactoylglutathione lyase activity
EXW52_18780	COG3300	MHYT domain
EXW52_18780	COG5001	Diguanylate cyclase
EXW52_18820	COG1346	cytolysis
EXW52_18830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW52_18835	COG0596	Alpha beta hydrolase
EXW52_18835	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW52_18840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW52_18850	COG2188	Transcriptional regulator
EXW52_18855	COG2723	6-phospho-beta-galactosidase activity
EXW52_18865	COG3773	Cell wall hydrolase
EXW52_18875	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW52_18885	COG2723	6-phospho-beta-galactosidase activity
EXW52_18890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW52_18890	COG2190	(PTS) system
EXW52_18890	COG1263	PTS System
EXW52_18895	COG3711	transcriptional antiterminator
EXW52_18905	COG0640	Transcriptional regulator
EXW52_18910	COG0697	spore germination
EXW52_18915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW52_18920	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW52_18925	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW52_18935	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW52_18940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW52_18945	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW52_18950	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW52_18950	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW52_18960	COG2359	stage V sporulation protein S
EXW52_18965	COG1692	metallophosphoesterase
EXW52_18970	COG1418	mRNA catabolic process
EXW52_18975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW52_18980	COG1058	Belongs to the CinA family
EXW52_18980	COG1546	Belongs to the CinA family
EXW52_18985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW52_18990	COG1426	Protein conserved in bacteria
EXW52_19005	COG0300	oxidoreductase activity
EXW52_19010	COG0612	Peptidase, M16
EXW52_19015	COG0612	Peptidase, M16
EXW52_19020	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW52_19025	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW52_19030	COG3845	ABC transporter
EXW52_19035	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW52_19040	COG2188	Transcriptional regulator
EXW52_19050	COG1674	ftsk spoiiie
EXW52_19060	COG0740	serine-type endopeptidase activity
EXW52_19065	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW52_19075	COG0527	aspartate kinase activity
EXW52_19080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW52_19085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW52_19090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW52_19095	COG1873	PFAM PRC-barrel domain
EXW52_19100	COG0612	Peptidase, M16
EXW52_19105	COG0726	polysaccharide deacetylase
EXW52_19110	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW52_19120	COG0196	riboflavin kinase activity
EXW52_19130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW52_19135	COG1550	Protein conserved in bacteria
EXW52_19140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW52_19145	COG1358	cellular component organization or biogenesis
EXW52_19150	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW52_19155	COG0195	Participates in both transcription termination and antitermination
EXW52_19160	COG0779	Required for maturation of 30S ribosomal subunits
EXW52_19170	COG0442	prolyl-tRNA aminoacylation
EXW52_19175	COG0750	zinc metalloprotease
EXW52_19185	COG4589	Belongs to the CDS family
EXW52_19195	COG0233	cytoplasmic translational termination
EXW52_19200	COG0528	UMP kinase activity
EXW52_19205	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW52_19210	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW52_19215	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW52_19220	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW52_19225	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW52_19230	COG4974	Belongs to the 'phage' integrase family
EXW52_19235	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW52_19240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW52_19245	COG0758	DNA mediated transformation
EXW52_19250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW52_19255	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW52_19260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW52_19275	COG0335	large ribosomal subunit rRNA binding
EXW52_19280	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW52_19285	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW52_19290	COG1837	Belongs to the UPF0109 family
EXW52_19300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW52_19305	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EXW52_19310	COG0552	protein localization to endoplasmic reticulum
EXW52_19315	COG1196	nuclear chromosome segregation
EXW52_19320	COG0571	ribonuclease III activity
EXW52_19325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW52_19330	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_19335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW52_19340	COG0416	fatty acid biosynthetic process
EXW52_19345	COG2050	protein possibly involved in aromatic compounds catabolism
EXW52_19345	COG1349	DNA-binding transcription factor activity
EXW52_19350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW52_19355	COG1461	Dihydroxyacetone kinase
EXW52_19360	COG1302	Protein conserved in bacteria
EXW52_19375	COG1564	THIamine pyrophosphokinase
EXW52_19380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW52_19390	COG2815	serine threonine protein kinase
EXW52_19390	COG0515	serine threonine protein kinase
EXW52_19395	COG0631	protein serine/threonine phosphatase activity
EXW52_19400	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW52_19405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW52_19405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW52_19410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW52_19415	COG0242	peptide deformylase activity
EXW52_19420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW52_19425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW52_19430	COG1758	RNA polymerase activity
EXW52_19445	COG1561	YicC-like family, N-terminal region
EXW52_19450	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW52_19465	COG0006	proline dipeptidase activity
EXW52_19485	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW52_19505	COG0167	dihydroorotate dehydrogenase activity
EXW52_19510	COG0543	2 iron, 2 sulfur cluster binding
EXW52_19515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW52_19525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW52_19530	COG0540	Belongs to the ATCase OTCase family
EXW52_19540	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW52_19545	COG0564	pseudouridine synthase activity
EXW52_19550	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW52_19560	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW52_19565	COG3599	regulation of cell shape
EXW52_19570	COG2302	S4 RNA-binding domain
EXW52_19575	COG0762	integral membrane protein
EXW52_19580	COG1799	cell septum assembly
EXW52_19585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW52_19595	COG1873	PFAM PRC-barrel domain
EXW52_19600	COG1191	sigma factor activity
EXW52_19605	COG1191	sigma factor activity
EXW52_19615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW52_19620	COG0849	cell division
EXW52_19625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW52_19640	COG0772	Belongs to the SEDS family
EXW52_19645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW52_19650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW52_19655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW52_19660	COG0768	penicillin binding
EXW52_19665	COG0768	penicillin binding
EXW52_19675	COG0275	rRNA processing
EXW52_19680	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW52_19685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW52_19690	COG0454	-acetyltransferase
EXW52_19700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW52_19705	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW52_19710	COG1323	Belongs to the UPF0348 family
EXW52_19715	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW52_19720	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW52_19725	COG3314	Sporulation integral membrane protein YlbJ
EXW52_19735	COG0742	ribosomal rna small subunit methyltransferase
EXW52_19745	COG4471	UPF0298 protein
EXW52_19750	COG3679	Belongs to the UPF0342 family
EXW52_19755	COG0406	alpha-ribazole phosphatase activity
EXW52_19770	COG2340	Cysteine-rich secretory protein family
EXW52_19780	COG3336	cytochrome c oxidase
EXW52_19805	COG0109	protoheme IX farnesyltransferase activity
EXW52_19810	COG1612	heme a metabolic process
EXW52_19815	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW52_19825	COG0772	Belongs to the SEDS family
EXW52_19830	COG4838	Belongs to the UPF0358 family
EXW52_19835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW52_19840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW52_19850	COG4896	Protein conserved in bacteria
EXW52_19865	COG1217	gtp-binding protein TYPA
EXW52_19875	COG0483	inositol monophosphate 1-phosphatase activity
EXW52_19885	COG4493	Belongs to the UPF0637 family
EXW52_19890	COG4476	Belongs to the UPF0223 family
EXW52_19900	COG1982	Orn Lys Arg decarboxylase major
EXW52_19945	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW52_19950	COG0022	dehydrogenase e1 component
EXW52_19955	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW52_19970	COG0561	phosphatase activity
EXW52_19980	COG5503	Protein of unknown function (DUF1447)
EXW52_19985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW52_19990	COG0569	domain protein
EXW52_20000	COG1473	amidohydrolase
EXW52_20005	COG2171	N-acyltransferase activity
EXW52_20010	COG0583	DNA-binding transcription factor activity
EXW52_20015	COG0517	IMP dehydrogenase activity
EXW52_20025	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW52_20035	COG4703	Protein of unknown function (DUF1797)
EXW52_20050	COG2200	EAL domain
EXW52_20055	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_20060	COG1408	metallophosphoesterase
EXW52_20105	COG2814	Major facilitator Superfamily
EXW52_20115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW52_20125	COG3209	COG3209 Rhs family protein
EXW52_20135	COG2205	protein histidine kinase activity
EXW52_20145	COG0436	Aminotransferase
EXW52_20150	COG1609	Transcriptional regulator
EXW52_20155	COG3833	ABC-type maltose transport systems, permease component
EXW52_20160	COG1175	transmembrane transport
EXW52_20165	COG2182	Extracellular solute-binding protein
EXW52_20175	COG0366	Alpha amylase catalytic
EXW52_20180	COG3842	ATPase activity
EXW52_20220	COG0183	Belongs to the thiolase family
EXW52_20255	COG1695	Transcriptional regulator
EXW52_20260	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_20270	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW52_20275	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW52_20280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW52_20285	COG0436	Aminotransferase
EXW52_20290	COG1850	ribulose-bisphosphate carboxylase activity
EXW52_20295	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW52_20300	COG0235	Class ii aldolase
EXW52_20305	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW52_20320	COG2084	Dehydrogenase
EXW52_20330	COG2199	diguanylate cyclase activity
EXW52_20335	COG0778	Nitroreductase
EXW52_20360	COG1263	PTS System
EXW52_20360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW52_20360	COG2190	(PTS) system
EXW52_20365	COG3711	transcriptional antiterminator
EXW52_20375	COG2188	Transcriptional regulator
EXW52_20380	COG0363	glucosamine-6-phosphate deaminase activity
EXW52_20385	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW52_20395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW52_20405	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW52_20415	COG1547	Domain of unknown function (DUF309)
EXW52_20425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW52_20430	COG4086	secreted protein
EXW52_20435	COG0561	phosphatase activity
EXW52_20440	COG0697	spore germination
EXW52_20455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW52_20495	COG1686	Belongs to the peptidase S11 family
EXW52_20500	COG1725	Transcriptional regulator
EXW52_20505	COG1131	(ABC) transporter
EXW52_20525	COG1846	Transcriptional regulator
EXW52_20540	COG0598	Magnesium transport protein CorA
EXW52_20555	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW52_20565	COG4974	Belongs to the 'phage' integrase family
EXW52_20575	COG0735	belongs to the Fur family
EXW52_20580	COG1300	Membrane
EXW52_20600	COG0667	Aldo Keto reductase
EXW52_20605	COG0656	L-ascorbic acid biosynthetic process
EXW52_20610	COG0456	acetyltransferase
EXW52_20610	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW52_20620	COG4085	toxin activity
EXW52_20620	COG0737	Belongs to the 5'-nucleotidase family
EXW52_20620	COG1525	nuclease
EXW52_20625	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW52_20635	COG0596	Alpha beta hydrolase
EXW52_20640	COG2056	Na+-H+ antiporter family
EXW52_20645	COG1609	Transcriptional regulator
EXW52_20650	COG0456	acetyltransferase
EXW52_20655	COG1073	alpha beta
EXW52_20680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW52_20680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW52_20685	COG0307	riboflavin synthase, alpha
EXW52_20690	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW52_20690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW52_20710	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW52_20715	COG4106	trans-aconitate 2-methyltransferase activity
EXW52_20720	COG2226	methyltransferase
EXW52_20720	COG1073	alpha beta
EXW52_20725	COG0156	8-amino-7-oxononanoate synthase activity
EXW52_20735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW52_20745	COG1757	Na H antiporter
EXW52_20750	COG0737	Belongs to the 5'-nucleotidase family
EXW52_20760	COG1522	sequence-specific DNA binding
EXW52_20795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW52_20805	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW52_20815	COG0300	oxidoreductase activity
EXW52_20820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW52_20825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW52_20830	COG1760	l-serine dehydratase
EXW52_20835	COG1760	l-serine dehydratase
EXW52_20845	COG1234	tRNA 3'-trailer cleavage
EXW52_20880	COG1131	(ABC) transporter
EXW52_20910	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW52_20915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW52_20925	COG1376	ErfK ybiS ycfS ynhG family protein
EXW52_20930	COG4129	membrane
EXW52_20935	COG1126	abc transporter atp-binding protein
EXW52_20940	COG0765	amino acid transport
EXW52_20945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW52_20955	COG2816	NAD+ diphosphatase activity
EXW52_20960	COG2323	membrane
EXW52_20965	COG0772	Belongs to the SEDS family
EXW52_20975	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW52_20980	COG0022	dehydrogenase e1 component
EXW52_20985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW52_20990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW52_20995	COG3426	butyrate kinase activity
EXW52_21005	COG0280	phosphate acetyltransferase
EXW52_21015	COG3290	protein histidine kinase activity
EXW52_21015	COG3829	transcription factor binding
EXW52_21025	COG0584	glycerophosphoryl diester phosphodiesterase
EXW52_21030	COG3093	addiction module antidote protein HigA
EXW52_21070	COG0745	RESPONSE REGULATOR receiver
EXW52_21080	COG0750	zinc metalloprotease
EXW52_21085	COG0497	DNA recombination
EXW52_21090	COG1438	arginine binding
EXW52_21095	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW52_21100	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW52_21105	COG0142	geranyltranstransferase activity
EXW52_21110	COG1722	exodeoxyribonuclease VII activity
EXW52_21115	COG1570	exodeoxyribonuclease VII activity
EXW52_21120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW52_21125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW52_21130	COG1302	Protein conserved in bacteria
EXW52_21135	COG0439	Biotin carboxylase
EXW52_21140	COG0511	ligase activity, forming carbon-carbon bonds
EXW52_21185	COG3854	ATPases associated with a variety of cellular activities
EXW52_21205	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW52_21210	COG0006	proline dipeptidase activity
EXW52_21215	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW52_21225	COG3872	metal-dependent enzyme
EXW52_21235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW52_21240	COG1321	iron dependent repressor
EXW52_21270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW52_21280	COG1609	Transcriptional regulator
EXW52_21290	COG2076	Multidrug Resistance protein
EXW52_21295	COG2076	Multidrug Resistance protein
EXW52_21335	COG1725	Transcriptional regulator
EXW52_21350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW52_21355	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW52_21360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW52_21365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW52_21395	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW52_21420	COG4970	Tfp pilus assembly protein FimT
EXW52_21430	COG1459	type II secretion system
EXW52_21435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW52_21490	COG0646	methionine synthase
EXW52_21490	COG1410	methionine synthase
EXW52_21495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW52_21495	COG0646	methionine synthase
EXW52_21500	COG0626	cystathionine gamma-synthase activity
EXW52_21505	COG0626	cystathionine gamma-synthase activity
EXW52_21520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW52_21530	COG1940	carbohydrate kinase activity
EXW52_21535	COG4483	Protein conserved in bacteria
EXW52_21540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW52_21545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW52_21550	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW52_21555	COG0704	Plays a role in the regulation of phosphate uptake
EXW52_21565	COG0581	inorganic phosphate transmembrane transporter activity
EXW52_21570	COG0573	inorganic phosphate transmembrane transporter activity
EXW52_21575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW52_21580	COG0768	penicillin binding
EXW52_21585	COG0477	Major facilitator Superfamily
EXW52_21590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW52_21610	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW52_21615	COG0735	belongs to the Fur family
EXW52_21620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW52_21625	COG1121	(ABC) transporter
EXW52_21630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW52_21640	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW52_21655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW52_21660	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW52_21665	COG2384	SAM-dependent methyltransferase
EXW52_21675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW52_21680	COG0358	DNA primase activity
EXW52_21690	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW52_21695	COG0517	IMP dehydrogenase activity
EXW52_21700	COG1381	Involved in DNA repair and RecF pathway recombination
EXW52_21710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW52_21715	COG0295	cytidine deaminase activity
EXW52_21720	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW52_21725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW52_21730	COG1480	7TM receptor with intracellular HD hydrolase
EXW52_21735	COG1702	phosphate starvation-inducible protein PhoH
EXW52_21750	COG1610	YqeY-like protein
EXW52_21755	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW52_21760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW52_21765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW52_21775	COG0484	heat shock protein binding
EXW52_21780	COG0443	Heat shock 70 kDa protein
EXW52_21790	COG1420	regulation of RNA biosynthetic process
EXW52_21795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW52_21800	COG1733	regulation of RNA biosynthetic process
EXW52_21805	COG0481	GTPase activity
EXW52_21815	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW52_21820	COG0268	Binds directly to 16S ribosomal RNA
EXW52_21825	COG1466	dna polymerase III delta subunit
EXW52_21835	COG0658	competence protein
EXW52_21835	COG2333	competence protein COMEC
EXW52_21840	COG2131	deaminase
EXW52_21845	COG1596	polysaccharide export
EXW52_21845	COG1555	photosystem II stabilization
EXW52_21850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW52_21855	COG2226	methyltransferase
EXW52_21860	COG0799	negative regulation of ribosome biogenesis
EXW52_21865	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW52_21870	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW52_21875	COG1534	Rna-binding protein
EXW52_21880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW52_21885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW52_21890	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW52_21900	COG0688	phosphatidylethanolamine metabolic process
EXW52_21910	COG1595	DNA-templated transcription, initiation
EXW52_21915	COG2357	RelA SpoT domain protein
EXW52_21925	COG1785	Belongs to the alkaline phosphatase family
EXW52_21935	COG2267	carboxylic ester hydrolase activity
EXW52_21970	COG1404	Belongs to the peptidase S8 family
EXW52_21975	COG3186	Phenylalanine-4-hydroxylase
EXW52_21980	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW52_21985	COG2514	catechol 2,3-dioxygenase activity
EXW52_21990	COG2259	Doxx family
EXW52_22030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW52_22040	COG1012	belongs to the aldehyde dehydrogenase family
EXW52_22040	COG1454	alcohol dehydrogenase
EXW52_22045	COG0626	cystathionine gamma-synthase activity
EXW52_22050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW52_22055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW52_22060	COG2226	methyltransferase
EXW52_22075	COG0768	penicillin binding
EXW52_22080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW52_22085	COG0572	uridine kinase
EXW52_22090	COG0826	peptidase U32
EXW52_22095	COG0826	peptidase U32
EXW52_22100	COG4122	O-methyltransferase activity
EXW52_22105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW52_22115	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW52_22120	COG4472	Bacterial protein of unknown function (DUF965)
EXW52_22125	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW52_22135	COG0628	permease
EXW52_22155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW52_22165	COG0482	sulfurtransferase activity
EXW52_22170	COG1104	cysteine desulfurase activity
EXW52_22175	COG1959	2 iron, 2 sulfur cluster binding
EXW52_22180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW52_22190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW52_22195	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW52_22205	COG1490	D-aminoacyl-tRNA deacylase activity
EXW52_22210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW52_22215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW52_22220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW52_22220	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW52_22225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW52_22230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW52_22230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW52_22240	COG2244	polysaccharide biosynthetic process
EXW52_22245	COG2323	membrane
EXW52_22255	COG1862	Preprotein translocase
EXW52_22260	COG0343	queuine tRNA-ribosyltransferase activity
EXW52_22265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW52_22275	COG2255	four-way junction helicase activity
EXW52_22280	COG0632	four-way junction helicase activity
EXW52_22285	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW52_22315	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW52_22320	COG0157	Belongs to the NadC ModD family
EXW52_22325	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW52_22330	COG1104	cysteine desulfurase activity
EXW52_22335	COG1827	regulation of RNA biosynthetic process
EXW52_22340	COG2258	MOSC domain
EXW52_22345	COG0077	Prephenate dehydratase
EXW52_22350	COG0577	efflux transmembrane transporter activity
EXW52_22355	COG0577	efflux transmembrane transporter activity
EXW52_22360	COG1136	(ABC) transporter
EXW52_22365	COG5002	protein histidine kinase activity
EXW52_22370	COG0745	RESPONSE REGULATOR receiver
EXW52_22375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW52_22380	COG3290	protein histidine kinase activity
EXW52_22390	COG2868	ribosomal protein
EXW52_22400	COG1530	ribonuclease E activity
EXW52_22405	COG1994	Peptidase M50
EXW52_22410	COG0739	heme binding
EXW52_22415	COG2894	cell division
EXW52_22420	COG0850	regulation of cytokinetic process
EXW52_22435	COG1077	Cell shape determining protein MreB Mrl
EXW52_22440	COG2003	Belongs to the UPF0758 family
EXW52_22445	COG0424	maF-like protein
EXW52_22460	COG0285	dihydrofolate synthase activity
EXW52_22475	COG1388	LysM domain
EXW52_22480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW52_22485	COG0113	porphobilinogen synthase activity
EXW52_22490	COG1587	Uroporphyrinogen-III synthase
EXW52_22495	COG0181	hydroxymethylbilane synthase activity
EXW52_22500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW52_22505	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW52_22510	COG1846	Transcriptional regulator
EXW52_22515	COG1764	response to oxidative stress
EXW52_22520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW52_22530	COG0470	DNA polymerase III
EXW52_22530	COG1067	ATP-dependent peptidase activity
EXW52_22540	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW52_22570	COG0622	Phosphoesterase
EXW52_22580	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW52_22585	COG5401	PFAM Sporulation and spore germination
EXW52_22595	COG0477	Major facilitator Superfamily
EXW52_22605	COG1309	transcriptional regulator
EXW52_22615	COG2197	response regulator
EXW52_22620	COG2233	PERMEase
EXW52_22625	COG0402	S-adenosylhomocysteine deaminase activity
EXW52_22630	COG1983	PspC domain protein
EXW52_22635	COG1396	sequence-specific DNA binding
EXW52_22640	COG0697	spore germination
EXW52_22650	COG1959	2 iron, 2 sulfur cluster binding
EXW52_22655	COG1668	transmembrane transport
EXW52_22660	COG4152	abc transporter atp-binding protein
EXW52_22665	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW52_22670	COG1360	Flagellar Motor Protein
EXW52_22675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW52_22685	COG1876	peptidase activity
EXW52_22690	COG0824	Thioesterase
EXW52_22695	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW52_22700	COG1053	succinate dehydrogenase
EXW52_22705	COG2009	succinate dehydrogenase
EXW52_22710	COG1719	4-vinyl reductase, 4VR
EXW52_22715	COG0322	excinuclease ABC activity
EXW52_22720	COG3118	belongs to the thioredoxin family
EXW52_22725	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW52_22730	COG2086	electron transfer activity
EXW52_22735	COG1024	Enoyl-CoA hydratase
EXW52_22740	COG1309	transcriptional regulator
EXW52_22745	COG0318	PFAM AMP-dependent synthetase and ligase
EXW52_22770	COG2318	DinB family
EXW52_22795	COG1131	(ABC) transporter
EXW52_22800	COG2205	protein histidine kinase activity
EXW52_22805	COG0745	RESPONSE REGULATOR receiver
EXW52_22810	COG4895	conserved protein (DUF2196)
EXW52_22815	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW52_22825	COG2329	Antibiotic biosynthesis monooxygenase
EXW52_22830	COG4509	Sortase family
EXW52_22835	COG1120	ATPase activity
EXW52_22850	COG5386	Cell surface protein
EXW52_22860	COG5386	Cell surface protein
EXW52_22865	COG1114	Component of the transport system for branched-chain amino acids
EXW52_22875	COG1193	negative regulation of DNA recombination
EXW52_22880	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW52_22880	COG1796	DNA polymerase
EXW52_22885	COG1286	toxin biosynthetic process
EXW52_22890	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW52_22895	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW52_22925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW52_22930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW52_22940	COG1418	mRNA catabolic process
EXW52_22965	COG2814	Major facilitator Superfamily
EXW52_22970	COG1566	PFAM secretion protein HlyD family protein
EXW52_22975	COG1309	transcriptional regulator
EXW52_22980	COG1363	Peptidase, m42
EXW52_22990	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW52_23005	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW52_23015	COG1484	DNA-dependent DNA replication
EXW52_23020	COG3611	Membrane attachment protein
EXW52_23025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW52_23030	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW52_23035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW52_23040	COG0237	dephospho-CoA kinase activity
EXW52_23045	COG1971	Probably functions as a manganese efflux pump
EXW52_23055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW52_23055	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW52_23060	COG5002	protein histidine kinase activity
EXW52_23065	COG0745	RESPONSE REGULATOR receiver
EXW52_23080	COG0039	L-malate dehydrogenase activity
EXW52_23085	COG0538	isocitrate dehydrogenase activity
EXW52_23090	COG0372	Belongs to the citrate synthase family
EXW52_23110	COG0628	permease
EXW52_23115	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW52_23125	COG0205	6-phosphofructokinase activity
EXW52_23135	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW52_23140	COG1725	Transcriptional regulator
EXW52_23145	COG0281	malic enzyme
EXW52_23150	COG0587	DNA-directed DNA polymerase activity
EXW52_23165	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW52_23185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW52_23195	COG4109	DRTGG domain
EXW52_23200	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW52_23205	COG0006	proline dipeptidase activity
EXW52_23250	COG0662	Cupin 2, conserved barrel domain protein
EXW52_23260	COG1476	TRANSCRIPTIONal
EXW52_23275	COG1028	Short-chain dehydrogenase reductase Sdr
EXW52_23280	COG0589	response to stress
EXW52_23295	COG0165	Argininosuccinate lyase
EXW52_23300	COG0137	argininosuccinate synthase activity
EXW52_23315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW52_23335	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW52_23340	COG0827	DNA restriction-modification system
EXW52_23345	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW52_23350	COG3874	Sporulation protein YtfJ
EXW52_23365	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW52_23375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW52_23390	COG1104	cysteine desulfurase activity
EXW52_23395	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW52_23405	COG1309	transcriptional regulator
EXW52_23410	COG1956	GAF domain-containing protein
EXW52_23415	COG0626	cystathionine gamma-synthase activity
EXW52_23425	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW52_23450	COG1595	DNA-templated transcription, initiation
EXW52_23460	COG0110	maltose O-acetyltransferase activity
EXW52_23465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW52_23470	COG0454	-acetyltransferase
EXW52_23475	COG0517	IMP dehydrogenase activity
EXW52_23480	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW52_23500	COG0745	RESPONSE REGULATOR receiver
EXW52_23505	COG5002	protein histidine kinase activity
EXW52_23510	COG0666	response to abiotic stimulus
EXW52_23520	COG1970	mechanosensitive ion channel activity
EXW52_23540	COG1609	Transcriptional regulator
EXW52_23550	COG1605	Chorismate mutase
EXW52_23550	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW52_23555	COG4851	CamS sex pheromone cAM373 precursor
EXW52_23560	COG3118	belongs to the thioredoxin family
EXW52_23570	COG2309	aminopeptidase activity
EXW52_23590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW52_23595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW52_23605	COG1674	ftsk spoiiie
EXW52_23620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW52_23625	COG4848	Belongs to the UPF0354 family
EXW52_23630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW52_23635	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW52_23640	COG1363	Peptidase, m42
EXW52_23650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW52_23655	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW52_23665	COG0510	thiamine kinase activity
EXW52_23670	COG1523	belongs to the glycosyl hydrolase 13 family
EXW52_23680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW52_23685	COG1349	DNA-binding transcription factor activity
EXW52_23690	COG1187	pseudouridine synthase activity
EXW52_23695	COG2244	polysaccharide biosynthetic process
EXW52_23700	COG2081	HI0933 family
EXW52_23705	COG2814	Major facilitator Superfamily
EXW52_23715	COG3832	glyoxalase III activity
EXW52_23735	COG1329	Transcriptional regulator
EXW52_23760	COG0314	molybdopterin synthase activity
EXW52_23765	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW52_23770	COG0303	'Molybdopterin
EXW52_23775	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW52_23780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW52_23785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW52_23810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW52_23820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW52_23860	COG0495	leucyl-tRNA aminoacylation
EXW52_23865	COG2814	Major facilitator Superfamily
EXW52_23870	COG0475	glutathione-regulated potassium exporter activity
EXW52_23875	COG0490	domain, Protein
EXW52_23880	COG0582	viral genome integration into host DNA
EXW52_23895	COG1136	(ABC) transporter
EXW52_23910	COG1242	4 iron, 4 sulfur cluster binding
EXW52_23915	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW52_23935	COG2267	carboxylic ester hydrolase activity
EXW52_23940	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW52_23945	COG0671	phosphoesterase, PA-phosphatase related
EXW52_23950	COG0438	transferase activity, transferring glycosyl groups
EXW52_23965	COG0746	molybdenum cofactor guanylyltransferase activity
EXW52_23985	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW52_23990	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW52_24035	COG5002	protein histidine kinase activity
EXW52_24040	COG3852	Histidine kinase
EXW52_24045	COG0753	catalase activity
EXW52_24050	COG2267	carboxylic ester hydrolase activity
EXW52_24060	COG1368	sulfuric ester hydrolase activity
EXW52_24070	COG4895	conserved protein (DUF2196)
EXW52_24085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW52_24090	COG1116	anion transmembrane transporter activity
EXW52_24095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW52_24115	COG0494	nUDIX hydrolase
EXW52_24160	COG2076	Multidrug Resistance protein
EXW52_24165	COG2076	Multidrug Resistance protein
EXW52_24170	COG0789	Transcriptional regulator
EXW52_24175	COG1854	S-ribosylhomocysteine lyase activity
EXW52_24185	COG0288	reversible hydration of carbon dioxide
EXW52_24190	COG1271	oxidase subunit
EXW52_24195	COG1294	oxidase, subunit
EXW52_24225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW52_24245	COG1842	Phage shock protein A
EXW52_24270	COG3859	Proton-coupled thiamine transporter YuaJ
EXW52_24275	COG5002	protein histidine kinase activity
EXW52_24280	COG0745	RESPONSE REGULATOR receiver
EXW52_24305	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW52_24310	COG1597	lipid kinase activity
EXW52_24350	COG0586	Pfam SNARE associated Golgi protein
EXW52_24365	COG0577	efflux transmembrane transporter activity
EXW52_24370	COG1136	(ABC) transporter
EXW52_24375	COG2207	Transcriptional regulator
EXW52_24375	COG3708	Transcriptional regulator
EXW52_24385	COG1131	(ABC) transporter
EXW52_24390	COG5658	integral membrane protein
EXW52_24395	COG0640	Transcriptional regulator
EXW52_24400	COG0745	RESPONSE REGULATOR receiver
EXW52_24405	COG2205	protein histidine kinase activity
EXW52_24410	COG0577	efflux transmembrane transporter activity
EXW52_24415	COG0577	efflux transmembrane transporter activity
EXW52_24420	COG1136	(ABC) transporter
EXW52_24425	COG0577	efflux transmembrane transporter activity
EXW52_24440	COG2188	Transcriptional regulator
EXW52_24460	COG3964	amidohydrolase
EXW52_24480	COG4948	Mandelate Racemase Muconate Lactonizing
EXW52_24485	COG0318	PFAM AMP-dependent synthetase and ligase
EXW52_24490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW52_24500	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW52_24505	COG1169	isochorismate synthase
EXW52_24510	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW52_24515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW52_24520	COG1278	Cold shock
EXW52_24530	COG0789	Transcriptional regulator
EXW52_24540	COG0058	SHG alpha-glucan phosphorylase activity
EXW52_24550	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW52_24555	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW52_24560	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW52_24710	COG1285	pathogenesis
EXW52_24715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW52_24725	COG0166	Belongs to the GPI family
EXW52_24735	COG2155	Conserved Protein
EXW52_24740	COG1098	S1 RNA binding domain
EXW52_24745	COG0436	Aminotransferase
EXW52_24750	COG1522	sequence-specific DNA binding
EXW52_24755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW52_24760	COG2267	carboxylic ester hydrolase activity
EXW52_24770	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW52_24785	COG5018	Exonuclease
EXW52_24790	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW52_24810	COG2050	protein possibly involved in aromatic compounds catabolism
EXW52_24820	COG1268	BioY protein
EXW52_24825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW52_24830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW52_24840	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW52_24845	COG3584	3D domain protein
EXW52_24860	COG1252	NADH dehydrogenase
EXW52_24865	COG0492	ferredoxin-NADP+ reductase activity
EXW52_24870	COG3708	Transcriptional regulator
EXW52_24885	COG1683	Conserved Protein
EXW52_24910	COG0316	Belongs to the HesB IscA family
EXW52_24915	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW52_24920	COG4844	belongs to the
EXW52_24925	COG1252	NADH dehydrogenase
EXW52_24935	COG0390	transport system, permease component
EXW52_24940	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW52_24965	COG4837	Protein of unknown function (DUF1462)
EXW52_24970	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW52_24980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW52_24985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW52_25005	COG0577	efflux transmembrane transporter activity
EXW52_25005	COG1136	(ABC) transporter
EXW52_25010	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW52_25020	COG0647	UMP catabolic process
EXW52_25030	COG2445	Protein of unknown function DUF86
EXW52_25035	COG1494	fructose-1,6-bisphosphatase
EXW52_25055	COG4470	Protein conserved in bacteria
EXW52_25065	COG0789	Transcriptional regulator
EXW52_25070	COG4377	Putative membrane peptidase family (DUF2324)
EXW52_25090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW52_25095	COG0739	heme binding
EXW52_25105	COG3377	Domain of unknown function (DUF1805)
EXW52_25110	COG0737	Belongs to the 5'-nucleotidase family
EXW52_25115	COG1695	Transcriptional regulator
EXW52_25125	COG0719	Fe-S assembly protein
EXW52_25130	COG0822	iron-sulfur transferase activity
EXW52_25135	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW52_25140	COG0719	Fe-S assembly protein
EXW52_25145	COG0396	ATPase activity
EXW52_25150	COG1464	Belongs to the NlpA lipoprotein family
EXW52_25155	COG1464	Belongs to the NlpA lipoprotein family
EXW52_25160	COG2011	ABC-type metal ion transport system permease component
EXW52_25175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW52_25180	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW52_25185	COG0509	glycine decarboxylation via glycine cleavage system
EXW52_25190	COG1393	Belongs to the ArsC family
EXW52_25225	COG1309	transcriptional regulator
EXW52_25230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW52_25235	COG1960	acyl-CoA dehydrogenase activity
EXW52_25240	COG0183	Belongs to the thiolase family
EXW52_25245	COG1024	Enoyl-CoA hydratase
EXW52_25245	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW52_25255	COG1686	Belongs to the peptidase S11 family
EXW52_25260	COG0506	proline dehydrogenase activity
EXW52_25270	COG0011	TIGRFAM Protein of
EXW52_25275	COG0840	transmembrane signaling receptor activity
EXW52_25290	COG2814	Major facilitator Superfamily
EXW52_25295	COG0531	amino acid
EXW52_25320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW52_25355	COG0586	Pfam SNARE associated Golgi protein
EXW52_25365	COG1376	ErfK ybiS ycfS ynhG family protein
EXW52_25370	COG0745	RESPONSE REGULATOR receiver
EXW52_25375	COG5002	protein histidine kinase activity
EXW52_25385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW52_25395	COG0840	transmembrane signaling receptor activity
EXW52_25405	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW52_25410	COG3227	Zinc metalloprotease (Elastase)
EXW52_25415	COG1741	Belongs to the pirin family
EXW52_25430	COG0586	Pfam SNARE associated Golgi protein
EXW52_25435	COG0475	glutathione-regulated potassium exporter activity
EXW52_25440	COG0490	domain, Protein
EXW52_25445	COG1115	amino acid carrier protein
EXW52_25450	COG0783	Belongs to the Dps family
EXW52_25460	COG2318	DinB family
EXW52_25465	COG1611	Belongs to the LOG family
EXW52_25475	COG1528	Iron-storage protein
EXW52_25480	COG2311	Membrane
EXW52_25485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW52_25490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW52_25495	COG1115	amino acid carrier protein
EXW52_25500	COG2910	NAD(P)H-binding
EXW52_25515	COG0656	L-ascorbic acid biosynthetic process
EXW52_25520	COG2814	Major facilitator Superfamily
EXW52_25525	COG1733	regulation of RNA biosynthetic process
EXW52_25535	COG1252	NADH dehydrogenase
EXW52_25555	COG3290	protein histidine kinase activity
EXW52_25555	COG0840	transmembrane signaling receptor activity
EXW52_25580	COG3655	Transcriptional regulator
EXW52_25595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW52_25605	COG1733	regulation of RNA biosynthetic process
EXW52_25610	COG0778	Nitroreductase
EXW52_25615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW52_25620	COG4224	UPF0291 protein
EXW52_25625	COG1522	sequence-specific DNA binding
EXW52_25630	COG0288	reversible hydration of carbon dioxide
EXW52_25635	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW52_25640	COG2233	PERMEase
EXW52_25665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW52_25685	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW52_25695	COG0557	exoribonuclease II activity
EXW52_25700	COG1647	Serine aminopeptidase, S33
EXW52_25705	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW52_25710	COG1346	cytolysis
EXW52_25725	COG0148	phosphopyruvate hydratase activity
EXW52_25735	COG0149	triose-phosphate isomerase activity
EXW52_25740	COG0126	phosphoglycerate kinase activity
EXW52_25745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW52_25760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW52_25785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW52_25800	COG2323	membrane
EXW52_25815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW52_25820	COG1481	regulation of sporulation
EXW52_25825	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW52_25830	COG1660	Displays ATPase and GTPase activities
EXW52_25835	COG1051	belongs to the nudix hydrolase family
EXW52_25845	COG0492	ferredoxin-NADP+ reductase activity
EXW52_25850	COG0457	Tetratricopeptide repeat
EXW52_25855	COG0110	maltose O-acetyltransferase activity
EXW52_25860	COG0546	phosphoglycolate phosphatase activity
EXW52_25865	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW52_25870	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW52_25875	COG1950	PFAM Membrane protein of
EXW52_25885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW52_25905	COG0789	Transcriptional regulator
EXW52_25940	COG0583	DNA-binding transcription factor activity
EXW52_25945	COG0789	Transcriptional regulator
EXW52_25950	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW52_25955	COG0488	(ABC) transporter
EXW52_25965	COG1132	(ABC) transporter
EXW52_25970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW52_25975	COG0793	Belongs to the peptidase S41A family
EXW52_25975	COG3409	Peptidoglycan-binding domain 1 protein
EXW52_25980	COG2177	Part of the ABC transporter FtsEX involved in
EXW52_25985	COG2884	Cell division ATP-binding protein ftsE
EXW52_26025	COG1278	Cold shock
EXW52_26030	COG1040	competence protein
EXW52_26035	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW52_26040	COG1388	LysM domain
EXW52_26040	COG0791	NLP P60 protein
EXW52_26045	COG1733	regulation of RNA biosynthetic process
EXW52_26050	COG1307	EDD domain protein, DegV family
EXW52_26055	COG1739	Uncharacterized protein family UPF0029
EXW52_26060	COG1316	TRANSCRIPTIONal
EXW52_26065	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW52_26070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW52_26075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW52_26085	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW52_26085	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW52_26105	COG1486	melibiose metabolic process
EXW52_26110	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW52_26115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW52_26125	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW52_26135	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW52_26145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW52_26150	COG1301	dicarboxylic acid transport
EXW52_26165	COG1511	domain protein
EXW52_26170	COG0583	DNA-binding transcription factor activity
EXW52_26175	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW52_26180	COG1271	oxidase subunit
EXW52_26185	COG1294	oxidase, subunit
EXW52_26190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW52_26195	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW52_26200	COG1620	l-lactate permease
EXW52_26210	COG2389	metal-binding protein
EXW52_26225	COG1368	sulfuric ester hydrolase activity
EXW52_26235	COG0791	NLP P60 protein
EXW52_26235	COG1388	LysM domain
EXW52_26240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW52_26250	COG1215	transferase activity, transferring glycosyl groups
EXW52_26255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW52_26265	COG1388	LysM domain
EXW52_26265	COG3584	3D domain protein
EXW52_26290	COG4715	Zinc finger, swim domain protein
EXW52_26295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW52_26335	COG0577	efflux transmembrane transporter activity
EXW52_26340	COG1136	(ABC) transporter
EXW52_26375	COG5002	protein histidine kinase activity
EXW52_26375	COG3850	Histidine kinase
EXW52_26380	COG0745	RESPONSE REGULATOR receiver
EXW52_26395	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EXW52_26405	COG0438	transferase activity, transferring glycosyl groups
EXW52_26440	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW52_26445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW52_26450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW52_26455	COG4464	protein tyrosine phosphatase activity
EXW52_26460	COG0489	protein tyrosine kinase activity
EXW52_26465	COG3944	biosynthesis protein
EXW52_26470	COG0489	protein tyrosine kinase activity
EXW52_26485	COG1609	Transcriptional regulator
EXW52_26500	COG0739	heme binding
EXW52_26515	COG3279	Response regulator of the LytR AlgR family
EXW52_26535	COG2385	sporulation resulting in formation of a cellular spore
EXW52_26550	COG4836	Membrane
EXW52_26555	COG1007	ATP synthesis coupled electron transport
EXW52_26560	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW52_26565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW52_26570	COG0713	ATP synthesis coupled electron transport
EXW52_26575	COG0839	Belongs to the complex I subunit 6 family
EXW52_26585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW52_26590	COG0649	NAD binding
EXW52_26595	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW52_26600	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW52_26605	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW52_26610	COG3300	MHYT domain
EXW52_26610	COG5001	Diguanylate cyclase
EXW52_26625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW52_26630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW52_26635	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW52_26640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW52_26645	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW52_26650	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW52_26660	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW52_26685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW52_26695	COG0698	ribose 5-phosphate isomerase
EXW52_26705	COG2190	(PTS) system
EXW52_26710	COG2259	Doxx family
EXW52_26715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW52_26725	COG1971	Probably functions as a manganese efflux pump
EXW52_26730	COG0009	L-threonylcarbamoyladenylate synthase
EXW52_26745	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW52_26750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW52_26755	COG1435	thymidine kinase activity
EXW52_26770	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW52_26775	COG1494	fructose-1,6-bisphosphatase
EXW52_26795	COG4821	SIS domain
EXW52_26800	COG0504	CTP synthase activity
EXW52_26805	COG3343	RNA polymerase activity
EXW52_26815	COG1960	acyl-CoA dehydrogenase activity
EXW52_26820	COG1960	acyl-CoA dehydrogenase activity
EXW52_26825	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW52_26830	COG0183	Belongs to the thiolase family
EXW52_26835	COG2181	nitrate reductase activity
EXW52_26835	COG0247	lactate metabolic process
EXW52_26840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW52_26845	COG4294	response to UV
EXW52_26850	COG3300	MHYT domain
EXW52_26850	COG5001	Diguanylate cyclase
EXW52_26875	COG2197	response regulator
EXW52_26880	COG4585	Histidine kinase
EXW52_26885	COG0842	Transport permease protein
EXW52_26890	COG1131	(ABC) transporter
EXW52_26895	COG0024	Methionine aminopeptidase
EXW52_26905	COG2234	aminopeptidase activity
EXW52_26925	COG4506	Protein conserved in bacteria
EXW52_26930	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW52_26945	COG0010	Belongs to the arginase family
EXW52_26950	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW52_26955	COG2814	Major facilitator Superfamily
EXW52_26960	COG0789	Transcriptional regulator
EXW52_26965	COG0584	glycerophosphoryl diester phosphodiesterase
EXW52_26970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW52_26980	COG1994	Peptidase M50
EXW52_26990	COG1078	dGTPase activity
EXW52_26995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW52_27000	COG1120	ATPase activity
EXW52_27005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW52_27010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW52_27015	COG4844	belongs to the
EXW52_27030	COG0280	phosphate acetyltransferase
EXW52_27035	COG3253	May function as heme-dependent peroxidase
EXW52_27045	COG3773	Cell wall hydrolase
EXW52_27055	COG2363	Small membrane protein
EXW52_27070	COG2233	PERMEase
EXW52_27075	COG0561	phosphatase activity
EXW52_27080	COG2814	Major facilitator Superfamily
EXW52_27085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW52_27090	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW52_27095	COG1131	(ABC) transporter
EXW52_27100	COG2755	lipolytic protein G-D-S-L family
EXW52_27105	COG1609	Transcriptional regulator
EXW52_27115	COG0460	homoserine dehydrogenase
EXW52_27120	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW52_27125	COG2873	o-acetylhomoserine
EXW52_27135	COG1011	Hydrolase
EXW52_27140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW52_27150	COG2197	response regulator
EXW52_27155	COG2203	Gaf domain
EXW52_27155	COG4585	Histidine kinase
EXW52_27160	COG0351	phosphomethylpyrimidine kinase
EXW52_27165	COG3706	GGDEF domain
EXW52_27170	COG2879	small protein
EXW52_27175	COG1966	Carbon starvation protein
EXW52_27180	COG3279	Response regulator of the LytR AlgR family
EXW52_27185	COG0477	Major facilitator Superfamily
EXW52_27210	COG0840	transmembrane signaling receptor activity
EXW52_27220	COG1607	acyl-coa hydrolase
EXW52_27225	COG1216	Glycosyl transferase, family 2
EXW52_27235	COG1216	Glycosyl transferase, family 2
EXW52_27245	COG0488	(ABC) transporter
EXW52_27250	COG1309	transcriptional regulator
EXW52_27255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW52_27260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW52_27260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW52_27265	COG0628	permease
EXW52_27275	COG1380	Effector of murein hydrolase LrgA
EXW52_27280	COG3279	Response regulator of the LytR AlgR family
EXW52_27285	COG3275	phosphorelay sensor kinase activity
EXW52_27290	COG2814	Major facilitator Superfamily
EXW52_27295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW52_27300	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW52_27310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW52_27360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW52_27365	COG1272	protein, Hemolysin III
EXW52_27390	COG1164	Oligoendopeptidase f
EXW52_27460	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW52_27470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW52_27475	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW52_27480	COG4853	Protein conserved in bacteria
EXW52_27490	COG5002	protein histidine kinase activity
EXW52_27495	COG0745	RESPONSE REGULATOR receiver
EXW52_27525	COG0305	Participates in initiation and elongation during chromosome replication
EXW52_27530	COG0359	binds to the 23S rRNA
EXW52_27535	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW52_27540	COG4241	membrane
EXW52_27550	COG0629	single-stranded DNA binding
EXW52_27555	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW52_27560	COG0012	GTP binding
EXW52_27565	COG4481	Protein conserved in bacteria
EXW52_27570	COG0668	transmembrane transport
EXW52_27580	COG1475	DNA binding
EXW52_27585	COG1192	Involved in chromosome partitioning
EXW52_27590	COG1475	DNA binding
EXW52_27595	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW52_27600	COG0445	tRNA wobble uridine modification
EXW52_27605	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW52_27610	COG1847	R3H domain protein
EXW52_27615	COG0706	membrane insertase activity
EXW52_27620	COG0594	ribonuclease P activity
EXW52_27625	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW52_27645	COG1278	Cold shock
EXW52_27650	COG0662	Cupin 2, conserved barrel domain protein
EXW52_27690	COG1136	(ABC) transporter
EXW52_27835	COG3620	sequence-specific DNA binding
EXW52_27845	COG0582	viral genome integration into host DNA
EXW52_27855	COG1192	Involved in chromosome partitioning
EXW52_27870	COG0024	Methionine aminopeptidase
EXW52_27875	COG1278	Cold shock
EXW52_28040	COG0791	NLP P60 protein
EXW52_28110	COG0551	DNA topoisomerase type I activity
EXW52_28110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW52_28205	COG0463	Glycosyl transferase, family 2
EXW52_28235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW52_28240	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW52_28245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW52_28250	COG0438	transferase activity, transferring glycosyl groups
EXW52_28270	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW52_28275	COG0438	transferase activity, transferring glycosyl groups
EXW52_28280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW52_28375	COG3773	Cell wall hydrolase
EXW52_28490	COG1780	Probably involved in ribonucleotide reductase function
EXW52_28515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW52_28530	COG4166	transmembrane transport
EXW52_28565	COG1192	Involved in chromosome partitioning
EXW52_28580	COG0741	lytic transglycosylase activity
EXW52_28590	COG1674	ftsk spoiiie
EXW52_28605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW52_28655	COG5002	protein histidine kinase activity
EXW52_28700	COG2186	Transcriptional regulator
EXW52_28820	COG0791	NLP P60 protein
EXW52_28820	COG3883	PFAM NLP P60 protein
EXW52_28860	COG0024	Methionine aminopeptidase
EXW52_28890	COG2002	toxin-antitoxin pair type II binding
EXW52_28895	COG0662	Cupin 2, conserved barrel domain protein
EXW52_28905	COG1923	regulation of RNA biosynthetic process
EXW52_28915	COG0477	Major facilitator Superfamily
EXW52_28925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW52_28925	COG0425	Belongs to the sulfur carrier protein TusA family
EXW52_28940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW52_28975	COG2211	Major facilitator Superfamily
EXW52_29005	COG0582	viral genome integration into host DNA
EXW52_29020	COG2378	regulation of single-species biofilm formation
EXW52_29025	COG2318	DinB family
EXW52_29070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW52_29105	COG2814	Major facilitator Superfamily
EXW52_29130	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW52_29145	COG2814	Major facilitator Superfamily
EXW52_29150	COG2357	RelA SpoT domain protein
EXW52_29195	COG0367	asparagine synthase
EXW52_29245	COG0640	Transcriptional regulator
EXW52_29320	COG4977	sequence-specific DNA binding
EXW52_29335	COG0083	homoserine kinase activity
EXW52_29355	COG1309	transcriptional regulator
EXW52_29360	COG2814	Major facilitator Superfamily
EXW52_29425	COG0814	amino acid
EXW52_29430	COG0697	spore germination
EXW52_29440	COG1760	l-serine dehydratase
EXW52_29445	COG1760	l-serine dehydratase
EXW52_29450	COG0814	amino acid
EXW52_29470	COG0662	Cupin 2, conserved barrel domain protein
EXW52_29485	COG0697	spore germination
EXW52_29530	COG1396	sequence-specific DNA binding
EXW52_29550	COG0840	transmembrane signaling receptor activity
EXW52_29555	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW52_29595	COG4974	Belongs to the 'phage' integrase family
EXW52_29620	COG1725	Transcriptional regulator
EXW52_29625	COG1131	(ABC) transporter
EXW52_29665	COG1329	Transcriptional regulator
EXW52_29780	COG2755	lipolytic protein G-D-S-L family
EXW52_29780	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW52_29815	COG0745	RESPONSE REGULATOR receiver
EXW52_29835	COG2720	vancomycin resistance protein
EXW52_29850	COG0833	amino acid
EXW52_29855	COG2040	homocysteine
EXW52_29950	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW52_29965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW52_30080	COG1404	Belongs to the peptidase S8 family
EXW52_30090	COG2814	Major facilitator Superfamily
EXW52_30095	COG2234	aminopeptidase activity
EXW52_30125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW52_30130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW52_30140	COG0456	acetyltransferase
EXW52_30165	COG1278	Cold shock