locus-tag	class	description
EXW38_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW38_00010	COG0592	DNA-directed DNA polymerase activity
EXW38_00015	COG2501	S4 domain
EXW38_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW38_00025	COG0187	DNA topoisomerase II activity
EXW38_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW38_00065	COG0516	GMP reductase activity
EXW38_00065	COG0517	IMP dehydrogenase activity
EXW38_00070	COG1686	Belongs to the peptidase S11 family
EXW38_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW38_00100	COG1428	Deoxynucleoside kinase
EXW38_00105	COG1428	Deoxynucleoside kinase
EXW38_00110	COG1335	isochorismatase
EXW38_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW38_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW38_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW38_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW38_00180	COG1982	Orn Lys Arg decarboxylase major
EXW38_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW38_00190	COG0470	DNA polymerase III
EXW38_00195	COG1774	PSP1 C-terminal conserved region
EXW38_00200	COG4467	Involved in initiation control of chromosome replication
EXW38_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW38_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW38_00220	COG2002	toxin-antitoxin pair type II binding
EXW38_00230	COG0084	hydrolase, TatD family'
EXW38_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW38_00250	COG4466	Protein conserved in bacteria
EXW38_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW38_00270	COG0251	oxidation-reduction process
EXW38_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW38_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW38_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW38_00305	COG2002	toxin-antitoxin pair type II binding
EXW38_00310	COG2244	polysaccharide biosynthetic process
EXW38_00315	COG3956	TIGRFAM MazG family protein
EXW38_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW38_00340	COG1098	S1 RNA binding domain
EXW38_00355	COG2208	phosphoserine phosphatase activity
EXW38_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW38_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW38_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW38_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW38_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW38_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW38_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW38_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW38_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW38_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW38_00420	COG1396	sequence-specific DNA binding
EXW38_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW38_00520	COG3880	PFAM UvrB UvrC protein
EXW38_00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW38_00530	COG0542	response to heat
EXW38_00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW38_00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW38_00545	COG4956	integral membrane protein (PIN domain superfamily)
EXW38_00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW38_00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW38_00565	COG1045	serine acetyltransferase
EXW38_00570	COG0215	cysteine-tRNA ligase activity
EXW38_00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW38_00585	COG3688	RNA-binding protein containing a PIN domain
EXW38_00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW38_00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW38_00605	COG0250	Participates in transcription elongation, termination and antitermination
EXW38_00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW38_00615	COG0081	regulation of translation
EXW38_00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW38_00625	COG0222	ribosome binding
EXW38_00630	COG2813	Specifically methylates the guanine in position
EXW38_00635	COG0085	RNA polymerase activity
EXW38_00640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW38_00645	COG1358	cellular component organization or biogenesis
EXW38_00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW38_00655	COG0049	tRNA binding
EXW38_00660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW38_00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW38_00670	COG0051	transcription antitermination factor activity, RNA binding
EXW38_00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW38_00680	COG0088	Forms part of the polypeptide exit tunnel
EXW38_00685	COG0089	rRNA binding
EXW38_00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW38_00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW38_00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW38_00710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EXW38_00715	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW38_00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW38_00725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EXW38_00730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW38_00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW38_00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW38_00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW38_00765	COG1841	ribosomal large subunit assembly
EXW38_00770	COG0200	Binds to the 23S rRNA
EXW38_00775	COG0201	protein transport
EXW38_00780	COG0563	adenylate kinase activity
EXW38_00785	COG0024	Methionine aminopeptidase
EXW38_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW38_00800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW38_00805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW38_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW38_00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW38_00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW38_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW38_00860	COG0489	protein tyrosine kinase activity
EXW38_00870	COG2194	sulfuric ester hydrolase activity
EXW38_00875	COG0726	polysaccharide deacetylase
EXW38_00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW38_00960	COG4856	YbbR-like protein
EXW38_01010	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_01015	COG2011	ABC-type metal ion transport system permease component
EXW38_01025	COG1464	Belongs to the NlpA lipoprotein family
EXW38_01030	COG0604	alcohol dehydrogenase
EXW38_01040	COG0277	FAD linked oxidase domain protein
EXW38_01045	COG2271	Major facilitator Superfamily
EXW38_01055	COG2814	Major facilitator Superfamily
EXW38_01075	COG0601	transmembrane transport
EXW38_01080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW38_01085	COG0444	Belongs to the ABC transporter superfamily
EXW38_01090	COG4608	Belongs to the ABC transporter superfamily
EXW38_01095	COG4166	transmembrane transport
EXW38_01105	COG2207	Transcriptional regulator
EXW38_01120	COG4166	transmembrane transport
EXW38_01125	COG4166	transmembrane transport
EXW38_01130	COG0656	L-ascorbic acid biosynthetic process
EXW38_01135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW38_01145	COG4149	molybdate abc transporter
EXW38_01150	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW38_01155	COG1910	domain protein
EXW38_01170	COG0697	spore germination
EXW38_01185	COG0204	Acyl-transferase
EXW38_01195	COG1609	Transcriptional regulator
EXW38_01205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_01220	COG5298	Protein conserved in bacteria
EXW38_01245	COG0488	(ABC) transporter
EXW38_01260	COG0747	negative chemotaxis
EXW38_01265	COG0747	negative chemotaxis
EXW38_01270	COG0601	transmembrane transport
EXW38_01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW38_01280	COG0444	Belongs to the ABC transporter superfamily
EXW38_01285	COG4608	Belongs to the ABC transporter superfamily
EXW38_01290	COG0561	phosphatase activity
EXW38_01320	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW38_01325	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW38_01335	COG0531	amino acid
EXW38_01340	COG2814	Major facilitator Superfamily
EXW38_01350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW38_01360	COG4294	response to UV
EXW38_01365	COG0705	Rhomboid family
EXW38_01370	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW38_01375	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW38_01380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW38_01385	COG0864	Transcriptional regulator
EXW38_01390	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW38_01395	COG2183	response to ionizing radiation
EXW38_01495	COG0802	atpase or kinase
EXW38_01500	COG1214	PFAM Peptidase M22, glycoprotease
EXW38_01505	COG0456	acetyltransferase
EXW38_01515	COG0488	(ABC) transporter
EXW38_01520	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW38_01530	COG1266	CAAX protease self-immunity
EXW38_01535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW38_01540	COG0459	protein refolding
EXW38_01545	COG0519	Catalyzes the synthesis of GMP from XMP
EXW38_01545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW38_01550	COG2252	PERMEase
EXW38_01560	COG5002	protein histidine kinase activity
EXW38_01585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW38_01630	COG4187	Peptidase family M20/M25/M40
EXW38_01670	COG0697	spore germination
EXW38_01690	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW38_01695	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW38_01700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW38_01710	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW38_01715	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW38_01720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW38_01725	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW38_01730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW38_01735	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW38_01740	COG0138	bifunctional purine biosynthesis protein purh
EXW38_01745	COG0151	Belongs to the GarS family
EXW38_01770	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW38_01775	COG0210	DNA helicase
EXW38_01780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW38_01785	COG4851	CamS sex pheromone cAM373 precursor
EXW38_01795	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_01800	COG1335	isochorismatase
EXW38_01810	COG2011	ABC-type metal ion transport system permease component
EXW38_01815	COG1464	Belongs to the NlpA lipoprotein family
EXW38_01825	COG0003	Pfam Anion-transporting ATPase
EXW38_01830	COG1846	Transcriptional regulator
EXW38_01835	COG4682	membrane
EXW38_01845	COG0154	amidase activity
EXW38_01850	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW38_01855	COG1597	lipid kinase activity
EXW38_01870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW38_01885	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_01890	COG2076	Multidrug Resistance protein
EXW38_01900	COG2309	aminopeptidase activity
EXW38_01915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_01925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW38_01935	COG4807	Protein conserved in bacteria
EXW38_01960	COG1757	Na H antiporter
EXW38_01965	COG1473	amidohydrolase
EXW38_01985	COG0450	alkyl hydroperoxide reductase
EXW38_01995	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW38_02005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_02010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_02015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_02025	COG0492	ferredoxin-NADP+ reductase activity
EXW38_02040	COG0166	Belongs to the GPI family
EXW38_02065	COG5002	protein histidine kinase activity
EXW38_02080	COG3541	Predicted nucleotidyltransferase
EXW38_02085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW38_02085	COG0723	plastoquinol--plastocyanin reductase activity
EXW38_02095	COG0765	amino acid transport
EXW38_02100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW38_02105	COG1126	abc transporter atp-binding protein
EXW38_02110	COG0840	transmembrane signaling receptor activity
EXW38_02115	COG0277	FAD linked oxidase domain protein
EXW38_02120	COG0366	Alpha amylase catalytic
EXW38_02125	COG2190	(PTS) system
EXW38_02125	COG1263	PTS System
EXW38_02125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_02150	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW38_02155	COG0352	thiamine-phosphate diphosphorylase activity
EXW38_02160	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW38_02180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW38_02185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW38_02190	COG1116	anion transmembrane transporter activity
EXW38_02195	COG0488	(ABC) transporter
EXW38_02220	COG2270	Major facilitator Superfamily
EXW38_02250	COG2310	stress, protein
EXW38_02255	COG2310	stress, protein
EXW38_02260	COG2310	stress, protein
EXW38_02265	COG0861	Integral membrane protein TerC family
EXW38_02275	COG3853	Toxic anion resistance protein (TelA)
EXW38_02285	COG4840	Belongs to the UPF0435 family
EXW38_02290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW38_02300	COG1295	ribonuclease BN
EXW38_02305	COG2217	Heavy metal translocating P-type atpase
EXW38_02310	COG0697	spore germination
EXW38_02330	COG0586	Pfam SNARE associated Golgi protein
EXW38_02345	COG3871	stress protein (general stress protein 26)
EXW38_02350	COG0387	Pfam Sodium calcium exchanger
EXW38_02360	COG0535	radical SAM domain protein
EXW38_02380	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW38_02385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EXW38_02390	COG0582	viral genome integration into host DNA
EXW38_02465	COG2002	toxin-antitoxin pair type II binding
EXW38_02535	COG0582	viral genome integration into host DNA
EXW38_02575	COG5484	DNA packaging
EXW38_02685	COG3829	transcription factor binding
EXW38_02695	COG0833	amino acid
EXW38_02705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW38_02730	COG1263	PTS System
EXW38_02730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_02735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW38_02755	COG1216	Glycosyl transferase, family 2
EXW38_02765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW38_02765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW38_02785	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW38_02790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW38_02805	COG1228	amidohydrolase
EXW38_02810	COG1090	epimerase
EXW38_02815	COG2137	regulation of response to DNA damage stimulus
EXW38_02840	COG1988	membrane-bound metal-dependent
EXW38_02845	COG1194	a g-specific adenine glycosylase
EXW38_02860	COG3557	Belongs to the UPF0374 family
EXW38_02865	COG1132	(ABC) transporter
EXW38_02870	COG4129	membrane
EXW38_02880	COG0070	glutamate synthase
EXW38_02880	COG0069	glutamate synthase activity
EXW38_02880	COG0067	glutamate synthase
EXW38_02885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW38_02890	COG4555	ABC transporter
EXW38_02910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW38_02915	COG0735	belongs to the Fur family
EXW38_03020	COG4974	Belongs to the 'phage' integrase family
EXW38_03040	COG4695	Portal protein
EXW38_03120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW38_03125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW38_03145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW38_03155	COG2766	serine protein kinase
EXW38_03175	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW38_03180	COG2268	Band 7 protein
EXW38_03185	COG3290	protein histidine kinase activity
EXW38_03190	COG4565	transcriptional regulatory protein
EXW38_03195	COG2851	Citrate transporter
EXW38_03215	COG0745	RESPONSE REGULATOR receiver
EXW38_03220	COG5002	protein histidine kinase activity
EXW38_03230	COG4990	cell redox homeostasis
EXW38_03240	COG3290	protein histidine kinase activity
EXW38_03245	COG4565	transcriptional regulatory protein
EXW38_03250	COG3493	citrate carrier protein
EXW38_03255	COG0281	malic enzyme
EXW38_03265	COG0697	spore germination
EXW38_03270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_03280	COG5002	protein histidine kinase activity
EXW38_03285	COG0745	RESPONSE REGULATOR receiver
EXW38_03290	COG0456	acetyltransferase
EXW38_03295	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW38_03300	COG3383	formate dehydrogenase (NAD+) activity
EXW38_03305	COG2427	Protein of unknown function (DUF1641)
EXW38_03320	COG0531	amino acid
EXW38_03330	COG0640	Transcriptional regulator
EXW38_03335	COG2217	Heavy metal translocating P-type atpase
EXW38_03340	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW38_03350	COG3227	Zinc metalloprotease (Elastase)
EXW38_03370	COG2720	vancomycin resistance protein
EXW38_03375	COG1316	TRANSCRIPTIONal
EXW38_03380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_03385	COG0346	lactoylglutathione lyase activity
EXW38_03390	COG1253	flavin adenine dinucleotide binding
EXW38_03395	COG1027	Aspartate ammonia-lyase
EXW38_03400	COG1620	l-lactate permease
EXW38_03405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW38_03425	COG3104	oligopeptide transport
EXW38_03430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_03435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_03440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_03455	COG0156	8-amino-7-oxononanoate synthase activity
EXW38_03460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW38_03470	COG4548	von Willebrand factor, type A
EXW38_03475	COG0714	Associated with various cellular activities
EXW38_03500	COG0531	amino acid
EXW38_03505	COG2188	Transcriptional regulator
EXW38_03510	COG1263	PTS System
EXW38_03510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_03515	COG0366	Alpha amylase catalytic
EXW38_03535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW38_03540	COG1115	amino acid carrier protein
EXW38_03545	COG1126	abc transporter atp-binding protein
EXW38_03550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW38_03555	COG0765	amino acid transport
EXW38_03560	COG0765	amino acid transport
EXW38_03565	COG0833	amino acid
EXW38_03580	COG2378	regulation of single-species biofilm formation
EXW38_03585	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW38_03590	COG5002	protein histidine kinase activity
EXW38_03605	COG0659	secondary active sulfate transmembrane transporter activity
EXW38_03630	COG0601	transmembrane transport
EXW38_03635	COG4608	Belongs to the ABC transporter superfamily
EXW38_03645	COG2271	Major facilitator Superfamily
EXW38_03650	COG1846	Transcriptional regulator
EXW38_03655	COG0477	Major facilitator Superfamily
EXW38_03660	COG1609	Transcriptional regulator
EXW38_03665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW38_03670	COG1869	D-ribose catabolic process
EXW38_03680	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW38_03685	COG1879	ABC-type sugar transport system periplasmic component
EXW38_03715	COG1063	alcohol dehydrogenase
EXW38_03760	COG0840	transmembrane signaling receptor activity
EXW38_03765	COG3583	domain protein
EXW38_03765	COG3584	3D domain protein
EXW38_03770	COG1476	TRANSCRIPTIONal
EXW38_03790	COG3104	oligopeptide transport
EXW38_03795	COG1114	Component of the transport system for branched-chain amino acids
EXW38_03810	COG1113	amino acid transport
EXW38_03815	COG2252	PERMEase
EXW38_03830	COG2153	protein acetylation
EXW38_03840	COG0475	glutathione-regulated potassium exporter activity
EXW38_03840	COG0569	domain protein
EXW38_03850	COG1845	cytochrome c oxidase, subunit III
EXW38_03855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW38_03860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EXW38_03865	COG0833	amino acid
EXW38_03870	COG4990	cell redox homeostasis
EXW38_03885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW38_03890	COG0697	spore germination
EXW38_03895	COG0531	amino acid
EXW38_03905	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW38_03910	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW38_03920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW38_03925	COG0573	inorganic phosphate transmembrane transporter activity
EXW38_03930	COG0581	inorganic phosphate transmembrane transporter activity
EXW38_03940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW38_03985	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW38_04065	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW38_04080	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW38_04080	COG4991	sh3 domain protein
EXW38_04080	COG3103	Sh3 type 3 domain protein
EXW38_04085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW38_04090	COG1116	anion transmembrane transporter activity
EXW38_04095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW38_04100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW38_04105	COG0352	thiamine-phosphate diphosphorylase activity
EXW38_04110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW38_04115	COG2104	thiamine diphosphate biosynthetic process
EXW38_04120	COG2022	thiamine diphosphate biosynthetic process
EXW38_04125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW38_04130	COG0351	phosphomethylpyrimidine kinase
EXW38_04160	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW38_04165	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW38_04170	COG2205	protein histidine kinase activity
EXW38_04195	COG1136	(ABC) transporter
EXW38_04205	COG2252	PERMEase
EXW38_04210	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_04270	COG0778	Nitroreductase
EXW38_04275	COG2719	SpoVR family
EXW38_04300	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW38_04310	COG1937	Protein conserved in bacteria
EXW38_04315	COG0425	Belongs to the sulfur carrier protein TusA family
EXW38_04315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW38_04320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_04320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW38_04325	COG0425	Belongs to the sulfur carrier protein TusA family
EXW38_04330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW38_04335	COG2210	Belongs to the sulfur carrier protein TusA family
EXW38_04340	COG0730	response to heat
EXW38_04355	COG1316	TRANSCRIPTIONal
EXW38_04360	COG0604	alcohol dehydrogenase
EXW38_04365	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW38_04375	COG2814	Major facilitator Superfamily
EXW38_04390	COG3711	transcriptional antiterminator
EXW38_04390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW38_04395	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW38_04400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW38_04420	COG3584	3D domain protein
EXW38_04420	COG1388	LysM domain
EXW38_04425	COG0577	efflux transmembrane transporter activity
EXW38_04430	COG1136	(ABC) transporter
EXW38_04440	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW38_04455	COG1114	Component of the transport system for branched-chain amino acids
EXW38_04460	COG3546	catalase activity
EXW38_04490	COG0586	Pfam SNARE associated Golgi protein
EXW38_04525	COG0531	amino acid
EXW38_04530	COG0475	glutathione-regulated potassium exporter activity
EXW38_04550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_04550	COG1263	PTS System
EXW38_04560	COG2259	Doxx family
EXW38_04595	COG0531	amino acid
EXW38_04605	COG0351	phosphomethylpyrimidine kinase
EXW38_04610	COG1757	Na H antiporter
EXW38_04615	COG4496	protein, YerC YecD
EXW38_04630	COG1522	sequence-specific DNA binding
EXW38_04640	COG0300	oxidoreductase activity
EXW38_04655	COG2076	Multidrug Resistance protein
EXW38_04660	COG1309	transcriptional regulator
EXW38_04670	COG2814	Major facilitator Superfamily
EXW38_04675	COG1733	regulation of RNA biosynthetic process
EXW38_04685	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW38_04710	COG4473	ABC transporter
EXW38_04715	COG0531	amino acid
EXW38_04720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EXW38_04725	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_04740	COG1132	(ABC) transporter
EXW38_04745	COG1132	(ABC) transporter
EXW38_04750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW38_04755	COG0765	amino acid transport
EXW38_04760	COG1126	abc transporter atp-binding protein
EXW38_04775	COG0189	ligase activity
EXW38_04785	COG4399	Belongs to the UPF0754 family
EXW38_04790	COG3679	Belongs to the UPF0342 family
EXW38_04805	COG0028	Belongs to the TPP enzyme family
EXW38_04810	COG3527	Alpha-acetolactate decarboxylase
EXW38_04815	COG0463	Glycosyl transferase, family 2
EXW38_04820	COG1216	Glycosyl transferase, family 2
EXW38_04825	COG2094	Belongs to the DNA glycosylase MPG family
EXW38_04830	COG0561	phosphatase activity
EXW38_04835	COG3409	Peptidoglycan-binding domain 1 protein
EXW38_04835	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW38_04840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW38_04845	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_04855	COG0586	Pfam SNARE associated Golgi protein
EXW38_04865	COG0789	Transcriptional regulator
EXW38_04865	COG4978	Transcriptional regulator
EXW38_04875	COG0659	secondary active sulfate transmembrane transporter activity
EXW38_04880	COG2244	polysaccharide biosynthetic process
EXW38_04900	COG1024	Enoyl-CoA hydratase
EXW38_04915	COG1363	Peptidase, m42
EXW38_04935	COG2318	DinB family
EXW38_04945	COG1113	amino acid transport
EXW38_04950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW38_04970	COG0579	oxidoreductase
EXW38_04975	COG2226	methyltransferase
EXW38_04980	COG3290	protein histidine kinase activity
EXW38_04980	COG3829	transcription factor binding
EXW38_04990	COG1301	dicarboxylic acid transport
EXW38_05000	COG0322	excinuclease ABC activity
EXW38_05050	COG0477	Major facilitator Superfamily
EXW38_05055	COG3290	protein histidine kinase activity
EXW38_05060	COG4565	transcriptional regulatory protein
EXW38_05065	COG3181	Tripartite tricarboxylate transporter family receptor
EXW38_05100	COG0305	Participates in initiation and elongation during chromosome replication
EXW38_05125	COG1842	Phage shock protein A
EXW38_05135	COG0477	Major facilitator Superfamily
EXW38_05185	COG1183	phosphatidylcholine synthase activity
EXW38_05200	COG2814	Major facilitator Superfamily
EXW38_05205	COG0640	Transcriptional regulator
EXW38_05235	COG2376	Dihydroxyacetone kinase
EXW38_05250	COG2376	Dihydroxyacetone kinase
EXW38_05275	COG2755	lipolytic protein G-D-S-L family
EXW38_05275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW38_05290	COG2720	vancomycin resistance protein
EXW38_05300	COG1335	isochorismatase
EXW38_05310	COG2373	Large extracellular alpha-helical protein
EXW38_05340	COG0076	glutamate decarboxylase activity
EXW38_05350	COG5658	integral membrane protein
EXW38_05365	COG1595	DNA-templated transcription, initiation
EXW38_05400	COG2807	transmembrane transport
EXW38_05405	COG2186	Transcriptional regulator
EXW38_05425	COG4585	Histidine kinase
EXW38_05430	COG2197	response regulator
EXW38_05455	COG0420	3'-5' exonuclease activity
EXW38_05460	COG4717	serine-type aminopeptidase activity
EXW38_05465	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW38_05475	COG0346	lactoylglutathione lyase activity
EXW38_05480	COG2267	carboxylic ester hydrolase activity
EXW38_05490	COG2140	Oxalate decarboxylase
EXW38_05495	COG3620	sequence-specific DNA binding
EXW38_05500	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW38_05505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW38_05510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW38_05515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW38_05520	COG1595	DNA-templated transcription, initiation
EXW38_05540	COG3973	AAA domain
EXW38_05570	COG0537	adenosine 5'-monophosphoramidase activity
EXW38_05575	COG1131	(ABC) transporter
EXW38_05580	COG4473	ABC transporter
EXW38_05630	COG0247	lactate metabolic process
EXW38_05635	COG1139	Iron-sulfur cluster binding protein
EXW38_05640	COG1556	Lactate utilization protein
EXW38_05680	COG1309	transcriptional regulator
EXW38_05685	COG3402	PFAM membrane-flanked domain
EXW38_05690	COG3428	Bacterial PH domain
EXW38_05715	COG3402	PFAM membrane-flanked domain
EXW38_05720	COG3428	Bacterial PH domain
EXW38_05725	COG2329	Antibiotic biosynthesis monooxygenase
EXW38_05730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW38_05735	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW38_05740	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW38_05745	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW38_05785	COG1309	transcriptional regulator
EXW38_05795	COG1216	Glycosyl transferase, family 2
EXW38_05795	COG0438	transferase activity, transferring glycosyl groups
EXW38_05815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_05830	COG2378	regulation of single-species biofilm formation
EXW38_05835	COG1609	Transcriptional regulator
EXW38_05845	COG1234	tRNA 3'-trailer cleavage
EXW38_05850	COG0095	Lipoate-protein ligase
EXW38_05870	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_05885	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW38_05890	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW38_05895	COG4208	sulfate ABC transporter
EXW38_05915	COG1408	metallophosphoesterase
EXW38_05920	COG1078	dGTPase activity
EXW38_05970	COG1595	DNA-templated transcription, initiation
EXW38_05980	COG2207	Transcriptional regulator
EXW38_05980	COG3708	Transcriptional regulator
EXW38_05985	COG2205	protein histidine kinase activity
EXW38_05990	COG0745	RESPONSE REGULATOR receiver
EXW38_06015	COG0501	Belongs to the peptidase M48B family
EXW38_06020	COG0697	spore germination
EXW38_06030	COG2373	Large extracellular alpha-helical protein
EXW38_06035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW38_06040	COG2224	Isocitrate lyase
EXW38_06050	COG1278	Cold shock
EXW38_06065	COG4903	ComK protein
EXW38_06075	COG0398	Pfam SNARE associated Golgi protein
EXW38_06105	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW38_06110	COG1074	ATP-dependent DNA helicase activity
EXW38_06160	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW38_06185	COG0367	asparagine synthase
EXW38_06195	COG0753	catalase activity
EXW38_06200	COG0004	ammonium transporteR
EXW38_06210	COG1666	GTP binding
EXW38_06215	COG2996	Protein conserved in bacteria
EXW38_06230	COG1329	Transcriptional regulator
EXW38_06265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW38_06275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_06290	COG0561	phosphatase activity
EXW38_06310	COG2267	carboxylic ester hydrolase activity
EXW38_06325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW38_06330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW38_06335	COG5504	Zn-dependent protease
EXW38_06345	COG0180	Tryptophanyl-tRNA synthetase
EXW38_06360	COG4166	transmembrane transport
EXW38_06365	COG0601	transmembrane transport
EXW38_06370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW38_06375	COG0444	Belongs to the ABC transporter superfamily
EXW38_06380	COG4608	Belongs to the ABC transporter superfamily
EXW38_06385	COG0534	Mate efflux family protein
EXW38_06390	COG4166	transmembrane transport
EXW38_06410	COG0861	Integral membrane protein TerC family
EXW38_06415	COG4862	establishment of competence for transformation
EXW38_06420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW38_06430	COG1164	Oligoendopeptidase f
EXW38_06440	COG2346	COG2346, Truncated hemoglobins
EXW38_06445	COG4116	CYTH
EXW38_06455	COG2357	RelA SpoT domain protein
EXW38_06465	COG0564	pseudouridine synthase activity
EXW38_06475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW38_06480	COG0772	Belongs to the SEDS family
EXW38_06490	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW38_06505	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW38_06550	COG2153	protein acetylation
EXW38_06555	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW38_06560	COG2382	esterase
EXW38_06585	COG5492	domain, Protein
EXW38_06590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW38_06610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW38_06610	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW38_06615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW38_06620	COG0134	indole-3-glycerol-phosphate synthase activity
EXW38_06625	COG0135	phosphoribosylanthranilate isomerase activity
EXW38_06635	COG0159	tryptophan synthase activity
EXW38_06645	COG1620	l-lactate permease
EXW38_06650	COG5634	Uncharacterized conserved protein (DUF2278)
EXW38_06690	COG2226	methyltransferase
EXW38_06710	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW38_06715	COG0567	Dehydrogenase, E1 component
EXW38_06720	COG1476	TRANSCRIPTIONal
EXW38_06765	COG1686	Belongs to the peptidase S11 family
EXW38_06770	COG0681	Belongs to the peptidase S26 family
EXW38_06805	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_06815	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW38_06820	COG1177	transmembrane transport
EXW38_06825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW38_06835	COG2409	Drug exporters of the RND superfamily
EXW38_06845	COG0564	pseudouridine synthase activity
EXW38_06855	COG2340	Cysteine-rich secretory protein family
EXW38_06860	COG0247	lactate metabolic process
EXW38_06865	COG0277	FAD linked oxidase domain protein
EXW38_06870	COG3835	regulator
EXW38_06880	COG0745	RESPONSE REGULATOR receiver
EXW38_06885	COG3850	Histidine kinase
EXW38_06885	COG5002	protein histidine kinase activity
EXW38_06890	COG2186	Transcriptional regulator
EXW38_06905	COG1556	Lactate utilization protein
EXW38_06910	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW38_06920	COG2116	formate transmembrane transporter activity
EXW38_06925	COG0861	Integral membrane protein TerC family
EXW38_06930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW38_06940	COG2030	dehydratase
EXW38_06965	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW38_06975	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW38_06990	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW38_06995	COG3842	ATPase activity
EXW38_07005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW38_07010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW38_07020	COG1349	DNA-binding transcription factor activity
EXW38_07030	COG0235	Class ii aldolase
EXW38_07040	COG2861	carbohydrate metabolic process
EXW38_07050	COG3852	Histidine kinase
EXW38_07055	COG1846	Transcriptional regulator
EXW38_07065	COG2318	DinB family
EXW38_07070	COG5002	protein histidine kinase activity
EXW38_07080	COG0720	synthase
EXW38_07090	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW38_07095	COG4873	Protein conserved in bacteria
EXW38_07105	COG0456	acetyltransferase
EXW38_07125	COG1780	Probably involved in ribonucleotide reductase function
EXW38_07140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW38_07145	COG0531	amino acid
EXW38_07160	COG2204	response regulator
EXW38_07165	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_07175	COG1725	Transcriptional regulator
EXW38_07180	COG1131	(ABC) transporter
EXW38_07190	COG1131	(ABC) transporter
EXW38_07195	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW38_07200	COG1266	CAAX protease self-immunity
EXW38_07210	COG1522	sequence-specific DNA binding
EXW38_07220	COG1335	isochorismatase
EXW38_07230	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW38_07235	COG2070	2-Nitropropane dioxygenase
EXW38_07240	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW38_07245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW38_07250	COG1696	Membrane protein involved in D-alanine export
EXW38_07270	COG0716	FMN binding
EXW38_07280	COG3173	Aminoglycoside phosphotransferase
EXW38_07295	COG0534	Mate efflux family protein
EXW38_07315	COG1846	Transcriptional regulator
EXW38_07330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW38_07340	COG3874	Sporulation protein YtfJ
EXW38_07360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW38_07365	COG0028	Belongs to the TPP enzyme family
EXW38_07370	COG0440	acetolactate synthase activity
EXW38_07380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW38_07390	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW38_07400	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW38_07405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW38_07415	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW38_07420	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW38_07425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW38_07430	COG0107	imidazoleglycerol-phosphate synthase activity
EXW38_07440	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW38_07445	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW38_07460	COG1183	phosphatidylcholine synthase activity
EXW38_07465	COG1368	sulfuric ester hydrolase activity
EXW38_07475	COG0019	diaminopimelate decarboxylase activity
EXW38_07490	COG2046	Belongs to the sulfate adenylyltransferase family
EXW38_07495	COG0529	Catalyzes the synthesis of activated sulfate
EXW38_07500	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW38_07520	COG1648	precorrin-2 dehydrogenase activity
EXW38_07525	COG0733	neurotransmitter:sodium symporter activity
EXW38_07545	COG1757	Na H antiporter
EXW38_07560	COG4758	membrane
EXW38_07565	COG4585	Histidine kinase
EXW38_07570	COG2197	response regulator
EXW38_07580	COG1114	Component of the transport system for branched-chain amino acids
EXW38_07590	COG2226	methyltransferase
EXW38_07630	COG0730	response to heat
EXW38_07635	COG0306	phosphate transporter
EXW38_07640	COG1392	Phosphate transport regulator
EXW38_07645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW38_07660	COG3852	Histidine kinase
EXW38_07665	COG1801	Protein of unknown function DUF72
EXW38_07685	COG0582	viral genome integration into host DNA
EXW38_07690	COG5002	protein histidine kinase activity
EXW38_07705	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW38_07705	COG0392	lysyltransferase activity
EXW38_07720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW38_07725	COG1686	Belongs to the peptidase S11 family
EXW38_07730	COG2715	membrane protein required for spore maturation
EXW38_07735	COG0700	Nucleoside recognition
EXW38_07740	COG1187	pseudouridine synthase activity
EXW38_07750	COG1333	cytochrome c biogenesis protein
EXW38_07755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW38_07760	COG0745	RESPONSE REGULATOR receiver
EXW38_07765	COG5002	protein histidine kinase activity
EXW38_07770	COG2096	Adenosyltransferase
EXW38_07775	COG4942	peptidase
EXW38_07785	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW38_07790	COG1141	Ferredoxin
EXW38_07800	COG4955	Helix-turn-helix domain
EXW38_07805	COG0514	ATP-dependent DNA helicase (RecQ)
EXW38_07810	COG1266	CAAX protease self-immunity
EXW38_07820	COG1408	metallophosphoesterase
EXW38_07835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW38_07855	COG0492	ferredoxin-NADP+ reductase activity
EXW38_07860	COG0252	asparaginase activity
EXW38_07870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW38_07880	COG1304	FMN binding
EXW38_07910	COG1160	GTP binding
EXW38_07915	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW38_07935	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW38_07950	COG0142	geranyltranstransferase activity
EXW38_07955	COG2226	methyltransferase
EXW38_07960	COG0142	geranyltranstransferase activity
EXW38_07975	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW38_07985	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW38_07990	COG0457	Tetratricopeptide repeat
EXW38_07995	COG5582	Belongs to the UPF0302 family
EXW38_08010	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW38_08015	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW38_08015	COG2010	Cytochrome c
EXW38_08020	COG4347	Protein of unknown function (DUF1405)
EXW38_08035	COG2738	Putative neutral zinc metallopeptidase
EXW38_08045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_08055	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW38_08060	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW38_08065	COG1803	Methylglyoxal synthase
EXW38_08070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW38_08075	COG0438	transferase activity, transferring glycosyl groups
EXW38_08080	COG0617	tRNA 3'-terminal CCA addition
EXW38_08090	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW38_08095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW38_08105	COG1199	ATP-dependent helicase activity
EXW38_08105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW38_08125	COG3935	DnaD domain protein
EXW38_08130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW38_08140	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW38_08140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW38_08145	COG3331	DNA recombination
EXW38_08180	COG4474	Belongs to the UPF0398 family
EXW38_08185	COG3599	regulation of cell shape
EXW38_08195	COG0116	Belongs to the methyltransferase superfamily
EXW38_08205	COG1199	ATP-dependent helicase activity
EXW38_08210	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW38_08220	COG0024	Methionine aminopeptidase
EXW38_08230	COG2233	PERMEase
EXW38_08235	COG2311	Membrane
EXW38_08240	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW38_08250	COG0456	acetyltransferase
EXW38_08260	COG2897	thiosulfate sulfurtransferase activity
EXW38_08300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW38_08340	COG0328	RNA-DNA hybrid ribonuclease activity
EXW38_08395	COG3403	YqcI/YcgG family
EXW38_08400	COG1280	lysine exporter protein (LysE YggA)
EXW38_08415	COG3162	membrane
EXW38_08420	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW38_08425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW38_08435	COG0475	glutathione-regulated potassium exporter activity
EXW38_08440	COG0789	Transcriptional regulator
EXW38_08440	COG4978	Transcriptional regulator
EXW38_08445	COG0534	Mate efflux family protein
EXW38_08450	COG2323	membrane
EXW38_08455	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW38_08475	COG1609	Transcriptional regulator
EXW38_08485	COG1175	transmembrane transport
EXW38_08490	COG0395	ABC-type sugar transport system, permease component
EXW38_08495	COG5578	integral membrane protein
EXW38_08505	COG1486	melibiose metabolic process
EXW38_08520	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EXW38_08525	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW38_08530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW38_08570	COG1923	regulation of RNA biosynthetic process
EXW38_08580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW38_08585	COG1360	Flagellar Motor Protein
EXW38_08590	COG2201	protein-glutamate methylesterase activity
EXW38_08595	COG2198	Histidine kinase
EXW38_08595	COG0643	Histidine kinase
EXW38_08600	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW38_08600	COG1776	CheC inhibitor of MCP methylation
EXW38_08615	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW38_08635	COG1256	bacterial-type flagellum assembly
EXW38_08640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW38_08660	COG1815	bacterial-type flagellum-dependent cell motility
EXW38_08665	COG1558	bacterial-type flagellum-dependent cell motility
EXW38_08675	COG1766	The M ring may be actively involved in energy transduction
EXW38_08680	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW38_08690	COG1157	protein secretion by the type III secretion system
EXW38_08710	COG1749	Flagellar hook protein flgE
EXW38_08725	COG0784	Response regulator, receiver
EXW38_08725	COG0835	chemotaxis
EXW38_08735	COG0861	Integral membrane protein TerC family
EXW38_08745	COG3383	formate dehydrogenase (NAD+) activity
EXW38_08750	COG2427	Protein of unknown function (DUF1641)
EXW38_08755	COG5609	conserved protein (DUF2294)
EXW38_08760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW38_08775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW38_08780	COG0303	'Molybdopterin
EXW38_08785	COG0314	molybdopterin synthase activity
EXW38_08790	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW38_08800	COG0489	protein tyrosine kinase activity
EXW38_08805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW38_08810	COG0741	lytic transglycosylase activity
EXW38_08820	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW38_08825	COG1776	CheC inhibitor of MCP methylation
EXW38_08825	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW38_08835	COG1338	Plays a role in the flagellum-specific transport system
EXW38_08840	COG1987	bacterial-type flagellum assembly
EXW38_08850	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW38_08855	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW38_08860	COG1419	protein localization to endoplasmic reticulum
EXW38_08865	COG4787	bacterial-type flagellum-dependent cell motility
EXW38_08895	COG1309	transcriptional regulator
EXW38_08910	COG0412	Dienelactone hydrolase
EXW38_08915	COG2329	Antibiotic biosynthesis monooxygenase
EXW38_08930	COG3764	Sortase (surface protein transpeptidase)
EXW38_08935	COG3764	Sortase (surface protein transpeptidase)
EXW38_08960	COG0583	DNA-binding transcription factor activity
EXW38_08965	COG3842	ATPase activity
EXW38_08970	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW38_09005	COG0406	alpha-ribazole phosphatase activity
EXW38_09025	COG1846	Transcriptional regulator
EXW38_09035	COG0367	asparagine synthase
EXW38_09065	COG1757	Na H antiporter
EXW38_09075	COG0277	FAD linked oxidase domain protein
EXW38_09090	COG0534	Mate efflux family protein
EXW38_09095	COG3340	Belongs to the peptidase S51 family
EXW38_09115	COG0785	Cytochrome C biogenesis protein
EXW38_09135	COG3048	D-serine ammonia-lyase activity
EXW38_09140	COG2733	membrane
EXW38_09180	COG1131	(ABC) transporter
EXW38_09200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW38_09205	COG0528	UMP kinase activity
EXW38_09215	COG1027	Aspartate ammonia-lyase
EXW38_09220	COG0281	malic enzyme
EXW38_09225	COG4191	Histidine kinase
EXW38_09230	COG0784	Response regulator, receiver
EXW38_09235	COG1846	Transcriptional regulator
EXW38_09245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW38_09260	COG2502	aspartate--ammonia ligase
EXW38_09265	COG3620	sequence-specific DNA binding
EXW38_09310	COG1695	Transcriptional regulator
EXW38_09325	COG0477	Major facilitator Superfamily
EXW38_09335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW38_09345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW38_09350	COG4166	transmembrane transport
EXW38_09355	COG2223	nitrite transmembrane transporter activity
EXW38_09360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW38_09375	COG2244	polysaccharide biosynthetic process
EXW38_09380	COG0733	neurotransmitter:sodium symporter activity
EXW38_09390	COG5566	PFAM Mor transcription activator
EXW38_09395	COG2323	membrane
EXW38_09410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW38_09425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW38_09450	COG2814	Major facilitator Superfamily
EXW38_09455	COG3384	dioxygenase
EXW38_09490	COG4166	transmembrane transport
EXW38_09520	COG0737	Belongs to the 5'-nucleotidase family
EXW38_09530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_09540	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW38_09545	COG1054	Belongs to the UPF0176 family
EXW38_09555	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW38_09560	COG0531	amino acid
EXW38_09580	COG1280	lysine exporter protein (LysE YggA)
EXW38_09595	COG2390	Transcriptional regulator
EXW38_09600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW38_09605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_09610	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW38_09625	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW38_09645	COG2267	carboxylic ester hydrolase activity
EXW38_09650	COG0583	DNA-binding transcription factor activity
EXW38_09670	COG0006	proline dipeptidase activity
EXW38_09680	COG2132	Multicopper oxidase
EXW38_09695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW38_09705	COG0583	DNA-binding transcription factor activity
EXW38_09725	COG1114	Component of the transport system for branched-chain amino acids
EXW38_09735	COG1276	copper resistance
EXW38_09735	COG2372	response to copper ion
EXW38_09740	COG4549	nuclear export factor GLE1
EXW38_09750	COG0697	spore germination
EXW38_09755	COG0583	DNA-binding transcription factor activity
EXW38_09760	COG1959	2 iron, 2 sulfur cluster binding
EXW38_09765	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW38_09780	COG0628	permease
EXW38_09795	COG1231	oxidoreductase activity
EXW38_09800	COG0523	cobalamin synthesis protein
EXW38_09810	COG0411	ABC transporter
EXW38_09830	COG0583	DNA-binding transcription factor activity
EXW38_09840	COG1942	4-Oxalocrotonate Tautomerase
EXW38_09855	COG0346	lactoylglutathione lyase activity
EXW38_09865	COG1271	oxidase subunit
EXW38_09870	COG1294	oxidase, subunit
EXW38_09875	COG4988	ABC transporter
EXW38_09880	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW38_09905	COG1686	Belongs to the peptidase S11 family
EXW38_09915	COG0791	NLP P60 protein
EXW38_09915	COG1388	LysM domain
EXW38_09925	COG1132	(ABC) transporter
EXW38_09930	COG0745	RESPONSE REGULATOR receiver
EXW38_09935	COG5002	protein histidine kinase activity
EXW38_09940	COG0300	oxidoreductase activity
EXW38_09945	COG4122	O-methyltransferase activity
EXW38_09975	COG0460	homoserine dehydrogenase
EXW38_09985	COG0083	homoserine kinase activity
EXW38_10000	COG1316	TRANSCRIPTIONal
EXW38_10015	COG1285	pathogenesis
EXW38_10040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW38_10050	COG1082	Xylose isomerase domain protein TIM barrel
EXW38_10060	COG2814	Major facilitator Superfamily
EXW38_10065	COG1279	arginine transmembrane transporter activity
EXW38_10070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_10080	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW38_10115	COG0577	efflux transmembrane transporter activity
EXW38_10120	COG2002	toxin-antitoxin pair type II binding
EXW38_10125	COG1404	Belongs to the peptidase S8 family
EXW38_10135	COG3842	ATPase activity
EXW38_10140	COG2508	Transcriptional regulator
EXW38_10150	COG1653	transport
EXW38_10155	COG1175	transmembrane transport
EXW38_10160	COG0395	ABC-type sugar transport system, permease component
EXW38_10165	COG5426	von Willebrand factor, type A
EXW38_10170	COG1940	carbohydrate kinase activity
EXW38_10175	COG2222	sugar isomerase
EXW38_10190	COG3684	Belongs to the aldolase LacD family
EXW38_10195	COG0366	Alpha amylase catalytic
EXW38_10200	COG0366	Alpha amylase catalytic
EXW38_10205	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW38_10250	COG3949	Membrane
EXW38_10255	COG0783	Belongs to the Dps family
EXW38_10270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW38_10280	COG1231	oxidoreductase activity
EXW38_10285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_10290	COG4989	oxidoreductase activity
EXW38_10295	COG0523	cobalamin synthesis protein
EXW38_10300	COG0456	acetyltransferase
EXW38_10305	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW38_10310	COG0702	epimerase
EXW38_10320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW38_10330	COG4166	transmembrane transport
EXW38_10335	COG0346	lactoylglutathione lyase activity
EXW38_10345	COG0406	alpha-ribazole phosphatase activity
EXW38_10355	COG5337	Spore coat protein CotH
EXW38_10360	COG1051	belongs to the nudix hydrolase family
EXW38_10365	COG0586	Pfam SNARE associated Golgi protein
EXW38_10370	COG2244	polysaccharide biosynthetic process
EXW38_10380	COG0701	Predicted permease
EXW38_10385	COG3689	TIGRFAM TIGR03943 family protein
EXW38_10390	COG1607	acyl-coa hydrolase
EXW38_10400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW38_10415	COG0702	epimerase
EXW38_10420	COG2839	Protein conserved in bacteria
EXW38_10425	COG1253	flavin adenine dinucleotide binding
EXW38_10440	COG1114	Component of the transport system for branched-chain amino acids
EXW38_10445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW38_10465	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW38_10480	COG1876	peptidase activity
EXW38_10495	COG2211	Major facilitator Superfamily
EXW38_10510	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW38_10520	COG0561	phosphatase activity
EXW38_10530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW38_10545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_10550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_10575	COG0456	acetyltransferase
EXW38_10660	COG3874	Sporulation protein YtfJ
EXW38_10685	COG2226	methyltransferase
EXW38_10705	COG0346	lactoylglutathione lyase activity
EXW38_10715	COG0604	alcohol dehydrogenase
EXW38_10720	COG1595	DNA-templated transcription, initiation
EXW38_10745	COG0426	domain, Protein
EXW38_10745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW38_10755	COG0386	Belongs to the glutathione peroxidase family
EXW38_10760	COG1305	Transglutaminase-like
EXW38_10765	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW38_10770	COG0714	Associated with various cellular activities
EXW38_10785	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW38_10790	COG1140	nitrate reductase beta subunit
EXW38_10795	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW38_10800	COG2181	nitrate reductase activity
EXW38_10805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW38_10810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW38_10815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW38_10820	COG0303	'Molybdopterin
EXW38_10825	COG0314	molybdopterin synthase activity
EXW38_10835	COG2223	nitrite transmembrane transporter activity
EXW38_10840	COG1648	precorrin-2 dehydrogenase activity
EXW38_10850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW38_10850	COG1587	Uroporphyrinogen-III synthase
EXW38_10855	COG2146	nitrite reductase [NAD(P)H] activity
EXW38_10860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW38_10870	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW38_10895	COG2359	stage V sporulation protein S
EXW38_10905	COG1418	mRNA catabolic process
EXW38_10910	COG0488	(ABC) transporter
EXW38_10930	COG1413	lyase activity
EXW38_10945	COG2136	Putative SAM-dependent methyltransferase
EXW38_10945	COG2521	methyltransferase
EXW38_10950	COG0018	arginyl-trna synthetase
EXW38_11005	COG0017	Asparaginyl-tRNA synthetase
EXW38_11025	COG1674	ftsk spoiiie
EXW38_11080	COG0733	neurotransmitter:sodium symporter activity
EXW38_11105	COG2610	gluconate transmembrane transporter activity
EXW38_11110	COG1454	alcohol dehydrogenase
EXW38_11125	COG0456	acetyltransferase
EXW38_11130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW38_11140	COG1131	(ABC) transporter
EXW38_11145	COG4473	ABC transporter
EXW38_11155	COG0546	phosphoglycolate phosphatase activity
EXW38_11180	COG0671	phosphoesterase, PA-phosphatase related
EXW38_11200	COG0768	penicillin binding
EXW38_11215	COG1272	protein, Hemolysin III
EXW38_11220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW38_11225	COG0805	protein transport
EXW38_11235	COG1307	EDD domain protein, DegV family
EXW38_11240	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW38_11245	COG1999	signal sequence binding
EXW38_11250	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW38_11255	COG0367	asparagine synthase
EXW38_11270	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW38_11275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_11280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW38_11295	COG1335	isochorismatase
EXW38_11305	COG0668	transmembrane transport
EXW38_11310	COG2203	Gaf domain
EXW38_11310	COG4585	Histidine kinase
EXW38_11315	COG2197	response regulator
EXW38_11320	COG1737	Transcriptional regulator
EXW38_11325	COG1064	alcohol dehydrogenase
EXW38_11340	COG1070	Carbohydrate kinase
EXW38_11350	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW38_11370	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW38_11400	COG1484	DNA-dependent DNA replication
EXW38_11440	COG0582	viral genome integration into host DNA
EXW38_11570	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW38_11605	COG0517	IMP dehydrogenase activity
EXW38_11605	COG1125	glycine betaine transport
EXW38_11610	COG1174	glycine betaine transport
EXW38_11645	COG1253	flavin adenine dinucleotide binding
EXW38_11650	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_11655	COG5506	Protein of unknown function (DUF1694)
EXW38_11670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW38_11675	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW38_11680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW38_11685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW38_11690	COG0456	acetyltransferase
EXW38_11695	COG3829	transcription factor binding
EXW38_11700	COG1509	lysine 2,3-aminomutase activity
EXW38_11710	COG4479	Belongs to the UPF0346 family
EXW38_11735	COG4991	sh3 domain protein
EXW38_11735	COG0515	serine threonine protein kinase
EXW38_11735	COG3064	Membrane
EXW38_11745	COG0671	phosphoesterase, PA-phosphatase related
EXW38_11750	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW38_11755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW38_11760	COG0582	viral genome integration into host DNA
EXW38_11775	COG5377	YqaJ viral recombinase family
EXW38_11820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW38_11845	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_11865	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW38_11865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW38_11875	COG2814	Major facilitator Superfamily
EXW38_11880	COG0372	Belongs to the citrate synthase family
EXW38_11885	COG2079	MmgE PrpD family protein
EXW38_11890	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW38_11895	COG1960	acyl-CoA dehydrogenase activity
EXW38_11900	COG2084	Dehydrogenase
EXW38_11905	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_11910	COG1280	lysine exporter protein (LysE YggA)
EXW38_11915	COG1024	Enoyl-CoA hydratase
EXW38_11930	COG0420	3'-5' exonuclease activity
EXW38_11935	COG0419	ATPase involved in DNA repair
EXW38_11950	COG2223	nitrite transmembrane transporter activity
EXW38_11955	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_11960	COG1169	isochorismate synthase
EXW38_11965	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW38_11970	COG1535	isochorismatase
EXW38_11970	COG3433	isochorismatase activity
EXW38_11975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW38_11980	COG3251	PFAM MbtH domain protein
EXW38_11985	COG2814	Major facilitator Superfamily
EXW38_12000	COG0776	regulation of translation
EXW38_12010	COG1115	amino acid carrier protein
EXW38_12025	COG2329	Antibiotic biosynthesis monooxygenase
EXW38_12040	COG1187	pseudouridine synthase activity
EXW38_12045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW38_12070	COG1136	(ABC) transporter
EXW38_12080	COG0596	Alpha beta hydrolase
EXW38_12095	COG0028	Belongs to the TPP enzyme family
EXW38_12105	COG4974	Belongs to the 'phage' integrase family
EXW38_12125	COG1253	flavin adenine dinucleotide binding
EXW38_12175	COG1846	Transcriptional regulator
EXW38_12190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_12195	COG1309	transcriptional regulator
EXW38_12205	COG0697	spore germination
EXW38_12210	COG0531	amino acid
EXW38_12225	COG1247	-acetyltransferase
EXW38_12235	COG0697	spore germination
EXW38_12260	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW38_12270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_12295	COG0561	phosphatase activity
EXW38_12305	COG0583	DNA-binding transcription factor activity
EXW38_12310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW38_12355	COG0583	DNA-binding transcription factor activity
EXW38_12360	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW38_12365	COG2258	MOSC domain
EXW38_12380	COG1132	(ABC) transporter
EXW38_12385	COG1132	(ABC) transporter
EXW38_12400	COG1396	sequence-specific DNA binding
EXW38_12475	COG1309	transcriptional regulator
EXW38_12490	COG1136	(ABC) transporter
EXW38_12490	COG0577	efflux transmembrane transporter activity
EXW38_12495	COG3615	Tellurite resistance protein tehB
EXW38_12495	COG0500	methyltransferase
EXW38_12505	COG0693	protein deglycase activity
EXW38_12560	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW38_12565	COG0110	maltose O-acetyltransferase activity
EXW38_12575	COG1686	Belongs to the peptidase S11 family
EXW38_12620	COG0768	penicillin binding
EXW38_12625	COG1595	DNA-templated transcription, initiation
EXW38_12635	COG0768	penicillin binding
EXW38_12640	COG0768	penicillin binding
EXW38_12670	COG1136	(ABC) transporter
EXW38_12705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_12715	COG5002	protein histidine kinase activity
EXW38_12745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_12760	COG0697	spore germination
EXW38_12785	COG3397	chitin binding
EXW38_12790	COG0823	Involved in the tonB-independent uptake of proteins
EXW38_12800	COG1408	metallophosphoesterase
EXW38_12810	COG1131	(ABC) transporter
EXW38_12820	COG1309	transcriptional regulator
EXW38_12825	COG1960	acyl-CoA dehydrogenase activity
EXW38_12830	COG0439	Biotin carboxylase
EXW38_12835	COG0511	ligase activity, forming carbon-carbon bonds
EXW38_12840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW38_12845	COG1024	Enoyl-CoA hydratase
EXW38_12850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW38_12855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW38_12910	COG2318	DinB family
EXW38_12915	COG1686	Belongs to the peptidase S11 family
EXW38_12955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW38_12980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW38_13010	COG1733	regulation of RNA biosynthetic process
EXW38_13015	COG2226	methyltransferase
EXW38_13025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW38_13055	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW38_13070	COG0697	spore germination
EXW38_13075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_13110	COG2323	membrane
EXW38_13115	COG2132	Multicopper oxidase
EXW38_13130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_13135	COG0697	spore germination
EXW38_13140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW38_13145	COG0201	protein transport
EXW38_13155	COG0737	Belongs to the 5'-nucleotidase family
EXW38_13160	COG3227	Zinc metalloprotease (Elastase)
EXW38_13165	COG1523	belongs to the glycosyl hydrolase 13 family
EXW38_13170	COG1073	alpha beta
EXW38_13180	COG0577	efflux transmembrane transporter activity
EXW38_13185	COG1136	(ABC) transporter
EXW38_13205	COG5002	protein histidine kinase activity
EXW38_13210	COG0745	RESPONSE REGULATOR receiver
EXW38_13215	COG1011	Hydrolase
EXW38_13235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW38_13240	COG1183	phosphatidylcholine synthase activity
EXW38_13250	COG1132	(ABC) transporter
EXW38_13260	COG3961	Belongs to the TPP enzyme family
EXW38_13280	COG0322	excinuclease ABC activity
EXW38_13305	COG2318	DinB family
EXW38_13320	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW38_13345	COG3878	Protein conserved in bacteria
EXW38_13355	COG0406	alpha-ribazole phosphatase activity
EXW38_13375	COG1051	belongs to the nudix hydrolase family
EXW38_13380	COG0592	DNA-directed DNA polymerase activity
EXW38_13395	COG2223	nitrite transmembrane transporter activity
EXW38_13400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW38_13410	COG0494	nUDIX hydrolase
EXW38_13440	COG0584	glycerophosphoryl diester phosphodiesterase
EXW38_13455	COG2814	Major facilitator Superfamily
EXW38_13495	COG0768	penicillin binding
EXW38_13500	COG0671	phosphoesterase, PA-phosphatase related
EXW38_13505	COG0604	alcohol dehydrogenase
EXW38_13510	COG5002	protein histidine kinase activity
EXW38_13515	COG0745	RESPONSE REGULATOR receiver
EXW38_13525	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW38_13535	COG2205	protein histidine kinase activity
EXW38_13550	COG1122	ATPase activity
EXW38_13555	COG4720	Psort location CytoplasmicMembrane, score
EXW38_13560	COG1794	racemase activity, acting on amino acids and derivatives
EXW38_13565	COG1819	glycosyl
EXW38_13575	COG0768	penicillin binding
EXW38_13580	COG5002	protein histidine kinase activity
EXW38_13585	COG0561	phosphatase activity
EXW38_13620	COG2124	cytochrome p450
EXW38_13650	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW38_13660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_13665	COG0460	homoserine dehydrogenase
EXW38_13685	COG0577	efflux transmembrane transporter activity
EXW38_13690	COG1136	(ABC) transporter
EXW38_13705	COG0488	(ABC) transporter
EXW38_13710	COG0667	Aldo Keto reductase
EXW38_13715	COG0583	DNA-binding transcription factor activity
EXW38_13720	COG2205	protein histidine kinase activity
EXW38_13725	COG0745	RESPONSE REGULATOR receiver
EXW38_13735	COG3773	Cell wall hydrolase
EXW38_13740	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW38_13780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_13795	COG2959	enzyme of heme biosynthesis
EXW38_13820	COG3483	tryptophan 2,3-dioxygenase activity
EXW38_13830	COG3844	kynureninase activity
EXW38_13835	COG1309	transcriptional regulator
EXW38_13855	COG1349	DNA-binding transcription factor activity
EXW38_13885	COG2223	nitrite transmembrane transporter activity
EXW38_13895	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_13930	COG4176	ABC-type proline glycine betaine transport system permease component
EXW38_13935	COG4175	Glycine betaine
EXW38_13935	COG0517	IMP dehydrogenase activity
EXW38_13960	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW38_13965	COG2153	protein acetylation
EXW38_13970	COG1819	glycosyl
EXW38_13990	COG2205	protein histidine kinase activity
EXW38_13995	COG2315	Protein conserved in bacteria
EXW38_14040	COG3973	AAA domain
EXW38_14060	COG0514	ATP-dependent DNA helicase (RecQ)
EXW38_14080	COG4637	Psort location Cytoplasmic, score
EXW38_14100	COG1227	inorganic diphosphatase activity
EXW38_14105	COG2318	DinB family
EXW38_14120	COG1162	GTPase activity
EXW38_14125	COG1115	amino acid carrier protein
EXW38_14130	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_14135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW38_14145	COG3938	Belongs to the proline racemase family
EXW38_14150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW38_14195	COG1078	dGTPase activity
EXW38_14200	COG0586	Pfam SNARE associated Golgi protein
EXW38_14215	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW38_14220	COG4166	transmembrane transport
EXW38_14230	COG4948	Mandelate Racemase Muconate Lactonizing
EXW38_14250	COG0667	Aldo Keto reductase
EXW38_14295	COG2936	dipeptidyl-peptidase activity
EXW38_14305	COG0745	RESPONSE REGULATOR receiver
EXW38_14335	COG1164	Oligoendopeptidase f
EXW38_14360	COG1307	EDD domain protein, DegV family
EXW38_14400	COG2814	Major facilitator Superfamily
EXW38_14410	COG1664	Polymer-forming cytoskeletal
EXW38_14415	COG0789	Transcriptional regulator
EXW38_14420	COG4533	DNA binding
EXW38_14425	COG2814	Major facilitator Superfamily
EXW38_14425	COG0477	Major facilitator Superfamily
EXW38_14440	COG2261	transglycosylase associated protein
EXW38_14455	COG2226	methyltransferase
EXW38_14490	COG0436	Aminotransferase
EXW38_14495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW38_14505	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW38_14520	COG1131	(ABC) transporter
EXW38_14570	COG0628	permease
EXW38_14595	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW38_14600	COG2720	vancomycin resistance protein
EXW38_14620	COG0697	spore germination
EXW38_14640	COG4912	Dna alkylation repair
EXW38_14680	COG2814	Major facilitator Superfamily
EXW38_14685	COG1368	sulfuric ester hydrolase activity
EXW38_14695	COG0488	(ABC) transporter
EXW38_14705	COG1033	growth of symbiont in host cell
EXW38_14705	COG2409	Drug exporters of the RND superfamily
EXW38_14710	COG1309	transcriptional regulator
EXW38_14725	COG0287	Prephenate dehydrogenase
EXW38_14740	COG1605	Chorismate mutase
EXW38_14740	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW38_14775	COG3584	3D domain protein
EXW38_14775	COG1388	LysM domain
EXW38_14785	COG0346	lactoylglutathione lyase activity
EXW38_14795	COG0277	FAD linked oxidase domain protein
EXW38_14815	COG2610	gluconate transmembrane transporter activity
EXW38_14820	COG1024	Enoyl-CoA hydratase
EXW38_14830	COG3290	protein histidine kinase activity
EXW38_14830	COG3829	transcription factor binding
EXW38_14840	COG0579	oxidoreductase
EXW38_14845	COG1879	ABC-type sugar transport system periplasmic component
EXW38_14855	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW38_14865	COG2390	Transcriptional regulator
EXW38_14870	COG1070	Carbohydrate kinase
EXW38_14885	COG2226	methyltransferase
EXW38_14910	COG0346	lactoylglutathione lyase activity
EXW38_14915	COG2329	Antibiotic biosynthesis monooxygenase
EXW38_14935	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW38_14940	COG2207	Transcriptional regulator
EXW38_14945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_14950	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW38_14955	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW38_14960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW38_14965	COG3239	Fatty acid desaturase
EXW38_14985	COG3842	ATPase activity
EXW38_15010	COG1175	transmembrane transport
EXW38_15015	COG1349	DNA-binding transcription factor activity
EXW38_15025	COG3655	Transcriptional regulator
EXW38_15045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_15050	COG0346	lactoylglutathione lyase activity
EXW38_15080	COG0714	Associated with various cellular activities
EXW38_15100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW38_15105	COG0753	catalase activity
EXW38_15145	COG0714	Associated with various cellular activities
EXW38_15155	COG0778	Nitroreductase
EXW38_15160	COG1846	Transcriptional regulator
EXW38_15190	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW38_15210	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_15215	COG0183	Belongs to the thiolase family
EXW38_15220	COG1024	Enoyl-CoA hydratase
EXW38_15225	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW38_15230	COG2723	6-phospho-beta-galactosidase activity
EXW38_15235	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW38_15240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW38_15255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW38_15265	COG2508	Transcriptional regulator
EXW38_15270	COG2814	Major facilitator Superfamily
EXW38_15305	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_15310	COG1309	transcriptional regulator
EXW38_15330	COG2207	Transcriptional regulator
EXW38_15335	COG0456	acetyltransferase
EXW38_15350	COG0697	spore germination
EXW38_15355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_15375	COG0642	Histidine kinase
EXW38_15380	COG0745	RESPONSE REGULATOR receiver
EXW38_15385	COG0596	Alpha beta hydrolase
EXW38_15395	COG0456	acetyltransferase
EXW38_15395	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW38_15420	COG0730	response to heat
EXW38_15430	COG0833	amino acid
EXW38_15440	COG4335	DNA alkylation repair
EXW38_15465	COG0768	penicillin binding
EXW38_15480	COG3104	oligopeptide transport
EXW38_15485	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW38_15500	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW38_15505	COG1984	allophanate hydrolase subunit 2
EXW38_15510	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW38_15515	COG1414	Transcriptional regulator
EXW38_15540	COG1960	acyl-CoA dehydrogenase activity
EXW38_15585	COG0574	Belongs to the PEP-utilizing enzyme family
EXW38_15585	COG3848	Pyruvate phosphate dikinase
EXW38_15635	COG0798	PFAM Bile acid sodium symporter
EXW38_15640	COG0346	lactoylglutathione lyase activity
EXW38_15645	COG0640	Transcriptional regulator
EXW38_15660	COG1309	transcriptional regulator
EXW38_15665	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_15670	COG1522	sequence-specific DNA binding
EXW38_15685	COG0346	lactoylglutathione lyase activity
EXW38_15700	COG0457	Tetratricopeptide repeat
EXW38_15715	COG0745	RESPONSE REGULATOR receiver
EXW38_15720	COG3850	Histidine kinase
EXW38_15720	COG5002	protein histidine kinase activity
EXW38_15765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW38_15770	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW38_15785	COG2226	methyltransferase
EXW38_15800	COG1690	Belongs to the RtcB family
EXW38_15810	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW38_15830	COG1136	(ABC) transporter
EXW38_15835	COG0577	efflux transmembrane transporter activity
EXW38_15855	COG3850	Histidine kinase
EXW38_15855	COG5002	protein histidine kinase activity
EXW38_15870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_15875	COG2271	Major facilitator Superfamily
EXW38_15880	COG1556	Lactate utilization protein
EXW38_15885	COG1139	Iron-sulfur cluster binding protein
EXW38_15895	COG0583	DNA-binding transcription factor activity
EXW38_15905	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW38_15920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW38_15940	COG1595	DNA-templated transcription, initiation
EXW38_15970	COG2814	Major facilitator Superfamily
EXW38_16010	COG1876	peptidase activity
EXW38_16015	COG2843	Capsule synthesis protein
EXW38_16030	COG0477	Major facilitator Superfamily
EXW38_16045	COG1846	Transcriptional regulator
EXW38_16050	COG2814	Major facilitator Superfamily
EXW38_16230	COG4187	Peptidase family M20/M25/M40
EXW38_16235	COG1414	Transcriptional regulator
EXW38_16245	COG0833	amino acid
EXW38_16265	COG2031	fatty acid transporter
EXW38_16275	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW38_16335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW38_16340	COG2356	endonuclease I
EXW38_16345	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW38_16355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW38_16375	COG1785	Belongs to the alkaline phosphatase family
EXW38_16390	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_16400	COG1131	(ABC) transporter
EXW38_16425	COG1011	Hydrolase
EXW38_16430	COG2365	Tyrosine phosphatase family
EXW38_16460	COG0628	permease
EXW38_16490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW38_16495	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW38_16505	COG1253	flavin adenine dinucleotide binding
EXW38_16510	COG0789	Transcriptional regulator
EXW38_16515	COG0697	spore germination
EXW38_16520	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW38_16525	COG3813	Protein conserved in bacteria
EXW38_16530	COG4702	Belongs to the UPF0303 family
EXW38_16540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_16550	COG0494	nUDIX hydrolase
EXW38_16565	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_16575	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_16580	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW38_16585	COG1733	regulation of RNA biosynthetic process
EXW38_16590	COG0640	Transcriptional regulator
EXW38_16610	COG1191	sigma factor activity
EXW38_16635	COG5002	protein histidine kinase activity
EXW38_16660	COG0657	acetylesterase activity
EXW38_16670	COG2814	Major facilitator Superfamily
EXW38_16675	COG1309	transcriptional regulator
EXW38_16690	COG2224	Isocitrate lyase
EXW38_16730	COG0814	amino acid
EXW38_16760	COG1151	hydroxylamine reductase activity
EXW38_16765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_16790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW38_16800	COG2072	flavoprotein involved in K transport
EXW38_16845	COG0714	Associated with various cellular activities
EXW38_16895	COG1695	Transcriptional regulator
EXW38_16900	COG0604	alcohol dehydrogenase
EXW38_16905	COG1113	amino acid transport
EXW38_16910	COG0456	acetyltransferase
EXW38_16925	COG5002	protein histidine kinase activity
EXW38_16930	COG0745	RESPONSE REGULATOR receiver
EXW38_16935	COG5002	protein histidine kinase activity
EXW38_16945	COG2814	Major facilitator Superfamily
EXW38_16955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW38_16960	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_16970	COG0534	Mate efflux family protein
EXW38_16975	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_16980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW38_16995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW38_17000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW38_17015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_17020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_17025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_17030	COG3739	integral membrane protein
EXW38_17065	COG1193	negative regulation of DNA recombination
EXW38_17075	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW38_17080	COG1164	Oligoendopeptidase f
EXW38_17105	COG3781	membrane
EXW38_17120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW38_17195	COG0640	Transcriptional regulator
EXW38_17200	COG0604	alcohol dehydrogenase
EXW38_17205	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW38_17230	COG2808	Putative FMN-binding domain
EXW38_17235	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW38_17245	COG0277	FAD linked oxidase domain protein
EXW38_17265	COG1285	pathogenesis
EXW38_17275	COG2514	catechol 2,3-dioxygenase activity
EXW38_17280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW38_17285	COG1126	abc transporter atp-binding protein
EXW38_17290	COG0765	amino acid transport
EXW38_17295	COG2720	vancomycin resistance protein
EXW38_17320	COG1278	Cold shock
EXW38_17330	COG0716	FMN binding
EXW38_17365	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_17375	COG0165	Argininosuccinate lyase
EXW38_17390	COG4145	pantothenate transmembrane transporter activity
EXW38_17400	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_17405	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_17415	COG1657	PFAM Prenyltransferase squalene oxidase
EXW38_17420	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW38_17425	COG2962	Rard protein
EXW38_17430	COG3326	Membrane
EXW38_17435	COG0531	amino acid
EXW38_17460	COG1737	Transcriptional regulator
EXW38_17465	COG2971	BadF BadG BcrA BcrD
EXW38_17475	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW38_17480	COG1486	melibiose metabolic process
EXW38_17490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW38_17515	COG2226	methyltransferase
EXW38_17520	COG4166	transmembrane transport
EXW38_17525	COG4166	transmembrane transport
EXW38_17530	COG4166	transmembrane transport
EXW38_17535	COG1316	TRANSCRIPTIONal
EXW38_17550	COG1131	(ABC) transporter
EXW38_17560	COG0673	inositol 2-dehydrogenase activity
EXW38_17565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW38_17570	COG0187	DNA topoisomerase II activity
EXW38_17575	COG1832	CoA-binding protein
EXW38_17580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW38_17585	COG0745	RESPONSE REGULATOR receiver
EXW38_17595	COG1328	CTP reductase activity
EXW38_17605	COG4841	protein insertion into membrane
EXW38_17610	COG0824	Thioesterase
EXW38_17635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW38_17655	COG1132	(ABC) transporter
EXW38_17660	COG1266	CAAX protease self-immunity
EXW38_17665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW38_17695	COG2211	Major facilitator Superfamily
EXW38_17705	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW38_17720	COG0183	Belongs to the thiolase family
EXW38_17725	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_17730	COG1268	BioY protein
EXW38_17735	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_17740	COG1396	sequence-specific DNA binding
EXW38_17775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_17790	COG5002	protein histidine kinase activity
EXW38_17800	COG0400	carboxylic ester hydrolase activity
EXW38_17810	COG0069	glutamate synthase activity
EXW38_17815	COG1902	pentaerythritol trinitrate reductase activity
EXW38_17820	COG1329	Transcriptional regulator
EXW38_17825	COG0010	Belongs to the arginase family
EXW38_17835	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW38_17840	COG2986	histidine ammonia-lyase
EXW38_17850	COG2226	methyltransferase
EXW38_17880	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW38_17885	COG0785	Cytochrome C biogenesis protein
EXW38_17900	COG1473	amidohydrolase
EXW38_17905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW38_17910	COG1131	(ABC) transporter
EXW38_17925	COG0583	DNA-binding transcription factor activity
EXW38_17935	COG1346	cytolysis
EXW38_17950	COG0730	response to heat
EXW38_17975	COG1132	(ABC) transporter
EXW38_17980	COG1132	(ABC) transporter
EXW38_17985	COG3763	UPF0154 protein
EXW38_18000	COG3639	organic phosphonate transmembrane transporter activity
EXW38_18005	COG3639	organic phosphonate transmembrane transporter activity
EXW38_18015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW38_18020	COG0737	Belongs to the 5'-nucleotidase family
EXW38_18030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW38_18035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW38_18050	COG1695	Transcriptional regulator
EXW38_18055	COG1132	(ABC) transporter
EXW38_18085	COG0367	asparagine synthase
EXW38_18090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW38_18100	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW38_18105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW38_18115	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW38_18115	COG3420	alginic acid biosynthetic process
EXW38_18120	COG1216	Glycosyl transferase, family 2
EXW38_18120	COG1442	glycosyl transferase family 8
EXW38_18150	COG0438	transferase activity, transferring glycosyl groups
EXW38_18160	COG1215	transferase activity, transferring glycosyl groups
EXW38_18165	COG0438	transferase activity, transferring glycosyl groups
EXW38_18170	COG0438	transferase activity, transferring glycosyl groups
EXW38_18175	COG1086	Polysaccharide biosynthesis protein
EXW38_18180	COG0489	protein tyrosine kinase activity
EXW38_18190	COG0174	glutamine synthetase
EXW38_18195	COG0789	Transcriptional regulator
EXW38_18200	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW38_18205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW38_18210	COG2860	membrane
EXW38_18215	COG0464	growth
EXW38_18235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW38_18245	COG3584	3D domain protein
EXW38_18245	COG1388	LysM domain
EXW38_18250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW38_18250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW38_18250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW38_18255	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW38_18260	COG1349	DNA-binding transcription factor activity
EXW38_18265	COG1979	alcohol dehydrogenase
EXW38_18270	COG2322	membrane
EXW38_18285	COG1473	amidohydrolase
EXW38_18290	COG1408	metallophosphoesterase
EXW38_18305	COG2217	Heavy metal translocating P-type atpase
EXW38_18310	COG2608	mercury ion transmembrane transporter activity
EXW38_18315	COG1937	Protein conserved in bacteria
EXW38_18345	COG2819	hydrolase of the alpha beta superfamily
EXW38_18350	COG1120	ATPase activity
EXW38_18355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_18360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_18365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_18370	COG0708	Exodeoxyribonuclease III
EXW38_18375	COG2169	Transcriptional regulator
EXW38_18380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW38_18385	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW38_18390	COG2706	6-phosphogluconolactonase activity
EXW38_18395	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW38_18400	COG2364	Membrane
EXW38_18415	COG0346	lactoylglutathione lyase activity
EXW38_18420	COG5001	Diguanylate cyclase
EXW38_18420	COG3300	MHYT domain
EXW38_18460	COG1346	cytolysis
EXW38_18470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_18475	COG2945	thiolester hydrolase activity
EXW38_18475	COG0596	Alpha beta hydrolase
EXW38_18480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW38_18490	COG2188	Transcriptional regulator
EXW38_18495	COG2723	6-phospho-beta-galactosidase activity
EXW38_18505	COG3773	Cell wall hydrolase
EXW38_18515	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW38_18525	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW38_18530	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW38_18540	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW38_18545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW38_18550	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW38_18555	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW38_18555	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW38_18565	COG2359	stage V sporulation protein S
EXW38_18570	COG1692	metallophosphoesterase
EXW38_18575	COG1418	mRNA catabolic process
EXW38_18580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW38_18585	COG1058	Belongs to the CinA family
EXW38_18585	COG1546	Belongs to the CinA family
EXW38_18590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW38_18595	COG1426	Protein conserved in bacteria
EXW38_18610	COG0300	oxidoreductase activity
EXW38_18615	COG0612	Peptidase, M16
EXW38_18620	COG0612	Peptidase, M16
EXW38_18625	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW38_18630	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW38_18635	COG3845	ABC transporter
EXW38_18640	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW38_18645	COG2188	Transcriptional regulator
EXW38_18655	COG1674	ftsk spoiiie
EXW38_18665	COG0740	serine-type endopeptidase activity
EXW38_18670	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW38_18680	COG0527	aspartate kinase activity
EXW38_18685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW38_18690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW38_18815	COG0740	serine-type endopeptidase activity
EXW38_18855	COG0582	viral genome integration into host DNA
EXW38_18900	COG0305	Participates in initiation and elongation during chromosome replication
EXW38_18935	COG3620	sequence-specific DNA binding
EXW38_18960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW38_18965	COG1873	PFAM PRC-barrel domain
EXW38_18970	COG0612	Peptidase, M16
EXW38_18975	COG0726	polysaccharide deacetylase
EXW38_18980	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW38_18990	COG0196	riboflavin kinase activity
EXW38_19000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW38_19005	COG1550	Protein conserved in bacteria
EXW38_19010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW38_19015	COG1358	cellular component organization or biogenesis
EXW38_19020	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW38_19025	COG0195	Participates in both transcription termination and antitermination
EXW38_19040	COG0442	prolyl-tRNA aminoacylation
EXW38_19045	COG0750	zinc metalloprotease
EXW38_19055	COG4589	Belongs to the CDS family
EXW38_19065	COG0233	cytoplasmic translational termination
EXW38_19070	COG0528	UMP kinase activity
EXW38_19075	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW38_19080	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW38_19085	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW38_19090	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW38_19095	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW38_19100	COG4974	Belongs to the 'phage' integrase family
EXW38_19105	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW38_19110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW38_19115	COG0758	DNA mediated transformation
EXW38_19120	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW38_19125	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW38_19130	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW38_19145	COG0335	large ribosomal subunit rRNA binding
EXW38_19150	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW38_19155	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW38_19160	COG1837	Belongs to the UPF0109 family
EXW38_19170	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW38_19180	COG0552	protein localization to endoplasmic reticulum
EXW38_19185	COG1196	nuclear chromosome segregation
EXW38_19190	COG0571	ribonuclease III activity
EXW38_19195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW38_19200	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_19205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW38_19210	COG0416	fatty acid biosynthetic process
EXW38_19220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW38_19225	COG1461	Dihydroxyacetone kinase
EXW38_19230	COG1302	Protein conserved in bacteria
EXW38_19245	COG1564	THIamine pyrophosphokinase
EXW38_19250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW38_19260	COG0515	serine threonine protein kinase
EXW38_19260	COG2815	serine threonine protein kinase
EXW38_19265	COG0631	protein serine/threonine phosphatase activity
EXW38_19270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW38_19275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW38_19275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW38_19280	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW38_19285	COG0242	peptide deformylase activity
EXW38_19290	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW38_19295	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW38_19300	COG1758	RNA polymerase activity
EXW38_19315	COG1561	YicC-like family, N-terminal region
EXW38_19320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW38_19335	COG0006	proline dipeptidase activity
EXW38_19350	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW38_19375	COG0167	dihydroorotate dehydrogenase activity
EXW38_19380	COG0543	2 iron, 2 sulfur cluster binding
EXW38_19385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW38_19395	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW38_19400	COG0540	Belongs to the ATCase OTCase family
EXW38_19410	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW38_19415	COG0564	pseudouridine synthase activity
EXW38_19435	COG3599	regulation of cell shape
EXW38_19440	COG2302	S4 RNA-binding domain
EXW38_19445	COG0762	integral membrane protein
EXW38_19450	COG1799	cell septum assembly
EXW38_19455	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW38_19465	COG1873	PFAM PRC-barrel domain
EXW38_19470	COG1191	sigma factor activity
EXW38_19475	COG1191	sigma factor activity
EXW38_19485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW38_19490	COG0849	cell division
EXW38_19495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW38_19510	COG0772	Belongs to the SEDS family
EXW38_19515	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW38_19520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW38_19525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW38_19530	COG0768	penicillin binding
EXW38_19535	COG0768	penicillin binding
EXW38_19545	COG0275	rRNA processing
EXW38_19550	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW38_19555	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW38_19560	COG0454	-acetyltransferase
EXW38_19570	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW38_19575	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW38_19580	COG1323	Belongs to the UPF0348 family
EXW38_19585	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW38_19590	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW38_19595	COG3314	Sporulation integral membrane protein YlbJ
EXW38_19605	COG0742	ribosomal rna small subunit methyltransferase
EXW38_19615	COG4471	UPF0298 protein
EXW38_19620	COG3679	Belongs to the UPF0342 family
EXW38_19625	COG0406	alpha-ribazole phosphatase activity
EXW38_19640	COG2340	Cysteine-rich secretory protein family
EXW38_19650	COG3336	cytochrome c oxidase
EXW38_19675	COG0109	protoheme IX farnesyltransferase activity
EXW38_19680	COG1612	heme a metabolic process
EXW38_19685	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW38_19695	COG0772	Belongs to the SEDS family
EXW38_19700	COG4838	Belongs to the UPF0358 family
EXW38_19705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW38_19710	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW38_19720	COG4896	Protein conserved in bacteria
EXW38_19735	COG1217	gtp-binding protein TYPA
EXW38_19745	COG0483	inositol monophosphate 1-phosphatase activity
EXW38_19755	COG4493	Belongs to the UPF0637 family
EXW38_19760	COG4476	Belongs to the UPF0223 family
EXW38_19765	COG1982	Orn Lys Arg decarboxylase major
EXW38_19815	COG0022	dehydrogenase e1 component
EXW38_19820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW38_19835	COG0561	phosphatase activity
EXW38_19845	COG5503	Protein of unknown function (DUF1447)
EXW38_19850	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW38_19855	COG0569	domain protein
EXW38_19865	COG1473	amidohydrolase
EXW38_19870	COG2171	N-acyltransferase activity
EXW38_19875	COG0583	DNA-binding transcription factor activity
EXW38_19880	COG0517	IMP dehydrogenase activity
EXW38_19890	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW38_19895	COG4703	Protein of unknown function (DUF1797)
EXW38_19910	COG2200	EAL domain
EXW38_19915	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_19920	COG1408	metallophosphoesterase
EXW38_19965	COG2814	Major facilitator Superfamily
EXW38_19975	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW38_19985	COG3209	COG3209 Rhs family protein
EXW38_19995	COG2205	protein histidine kinase activity
EXW38_20005	COG0436	Aminotransferase
EXW38_20010	COG1609	Transcriptional regulator
EXW38_20015	COG3833	ABC-type maltose transport systems, permease component
EXW38_20020	COG1175	transmembrane transport
EXW38_20025	COG2182	Extracellular solute-binding protein
EXW38_20035	COG0366	Alpha amylase catalytic
EXW38_20040	COG3842	ATPase activity
EXW38_20085	COG0183	Belongs to the thiolase family
EXW38_20125	COG1695	Transcriptional regulator
EXW38_20130	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_20140	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW38_20150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW38_20155	COG0436	Aminotransferase
EXW38_20160	COG1850	ribulose-bisphosphate carboxylase activity
EXW38_20165	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW38_20170	COG0235	Class ii aldolase
EXW38_20175	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW38_20190	COG2084	Dehydrogenase
EXW38_20200	COG2199	diguanylate cyclase activity
EXW38_20205	COG0778	Nitroreductase
EXW38_20230	COG2190	(PTS) system
EXW38_20230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_20230	COG1263	PTS System
EXW38_20235	COG3711	transcriptional antiterminator
EXW38_20245	COG2188	Transcriptional regulator
EXW38_20250	COG0363	glucosamine-6-phosphate deaminase activity
EXW38_20255	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW38_20265	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW38_20275	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW38_20285	COG1547	Domain of unknown function (DUF309)
EXW38_20295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW38_20300	COG4086	secreted protein
EXW38_20305	COG0561	phosphatase activity
EXW38_20310	COG0697	spore germination
EXW38_20325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW38_20365	COG1686	Belongs to the peptidase S11 family
EXW38_20375	COG1725	Transcriptional regulator
EXW38_20380	COG1131	(ABC) transporter
EXW38_20400	COG1846	Transcriptional regulator
EXW38_20415	COG0598	Magnesium transport protein CorA
EXW38_20430	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW38_20440	COG4974	Belongs to the 'phage' integrase family
EXW38_20450	COG0735	belongs to the Fur family
EXW38_20455	COG1300	Membrane
EXW38_20475	COG0667	Aldo Keto reductase
EXW38_20480	COG0656	L-ascorbic acid biosynthetic process
EXW38_20485	COG0456	acetyltransferase
EXW38_20485	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW38_20495	COG0737	Belongs to the 5'-nucleotidase family
EXW38_20495	COG1525	nuclease
EXW38_20495	COG4085	toxin activity
EXW38_20500	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW38_20510	COG0596	Alpha beta hydrolase
EXW38_20515	COG2056	Na+-H+ antiporter family
EXW38_20520	COG1609	Transcriptional regulator
EXW38_20525	COG0456	acetyltransferase
EXW38_20530	COG1073	alpha beta
EXW38_20545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW38_20545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW38_20550	COG0307	riboflavin synthase, alpha
EXW38_20555	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW38_20555	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW38_20570	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW38_20580	COG1073	alpha beta
EXW38_20580	COG2226	methyltransferase
EXW38_20585	COG0156	8-amino-7-oxononanoate synthase activity
EXW38_20595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW38_20610	COG1757	Na H antiporter
EXW38_20615	COG0737	Belongs to the 5'-nucleotidase family
EXW38_20625	COG1522	sequence-specific DNA binding
EXW38_20660	COG5444	nuclease activity
EXW38_20670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW38_20675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW38_20685	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW38_20695	COG0300	oxidoreductase activity
EXW38_20700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_20705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW38_20710	COG1760	l-serine dehydratase
EXW38_20715	COG1760	l-serine dehydratase
EXW38_20725	COG1234	tRNA 3'-trailer cleavage
EXW38_20760	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW38_20765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_20775	COG1376	ErfK ybiS ycfS ynhG family protein
EXW38_20780	COG4129	membrane
EXW38_20785	COG1126	abc transporter atp-binding protein
EXW38_20790	COG0765	amino acid transport
EXW38_20795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW38_20805	COG2816	NAD+ diphosphatase activity
EXW38_20810	COG2323	membrane
EXW38_20815	COG0772	Belongs to the SEDS family
EXW38_20820	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW38_20825	COG0022	dehydrogenase e1 component
EXW38_20830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW38_20835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW38_20840	COG3426	butyrate kinase activity
EXW38_20850	COG0280	phosphate acetyltransferase
EXW38_20860	COG3829	transcription factor binding
EXW38_20860	COG3290	protein histidine kinase activity
EXW38_20870	COG0584	glycerophosphoryl diester phosphodiesterase
EXW38_20875	COG3093	addiction module antidote protein HigA
EXW38_20885	COG0745	RESPONSE REGULATOR receiver
EXW38_20895	COG0750	zinc metalloprotease
EXW38_20900	COG0497	DNA recombination
EXW38_20905	COG1438	arginine binding
EXW38_20910	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW38_20915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW38_20920	COG0142	geranyltranstransferase activity
EXW38_20925	COG1722	exodeoxyribonuclease VII activity
EXW38_20935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW38_20940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW38_20945	COG1302	Protein conserved in bacteria
EXW38_20950	COG0439	Biotin carboxylase
EXW38_20955	COG0511	ligase activity, forming carbon-carbon bonds
EXW38_21000	COG3854	ATPases associated with a variety of cellular activities
EXW38_21020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW38_21025	COG0006	proline dipeptidase activity
EXW38_21040	COG3872	metal-dependent enzyme
EXW38_21050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW38_21085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW38_21095	COG1609	Transcriptional regulator
EXW38_21105	COG2076	Multidrug Resistance protein
EXW38_21110	COG2076	Multidrug Resistance protein
EXW38_21150	COG1725	Transcriptional regulator
EXW38_21165	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW38_21170	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW38_21175	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW38_21180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW38_21210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW38_21235	COG4970	Tfp pilus assembly protein FimT
EXW38_21240	COG4537	Required for transformation and DNA binding
EXW38_21245	COG1459	type II secretion system
EXW38_21250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW38_21330	COG0646	methionine synthase
EXW38_21330	COG1410	methionine synthase
EXW38_21335	COG0646	methionine synthase
EXW38_21335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW38_21340	COG0626	cystathionine gamma-synthase activity
EXW38_21345	COG0626	cystathionine gamma-synthase activity
EXW38_21365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_21375	COG1940	carbohydrate kinase activity
EXW38_21380	COG4483	Protein conserved in bacteria
EXW38_21385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW38_21390	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW38_21395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW38_21400	COG0704	Plays a role in the regulation of phosphate uptake
EXW38_21410	COG0581	inorganic phosphate transmembrane transporter activity
EXW38_21415	COG0573	inorganic phosphate transmembrane transporter activity
EXW38_21420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW38_21425	COG0768	penicillin binding
EXW38_21430	COG0477	Major facilitator Superfamily
EXW38_21435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW38_21450	COG1388	LysM domain
EXW38_21455	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW38_21460	COG0735	belongs to the Fur family
EXW38_21465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW38_21470	COG1121	(ABC) transporter
EXW38_21475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_21485	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW38_21505	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW38_21510	COG2384	SAM-dependent methyltransferase
EXW38_21515	COG2010	Cytochrome c
EXW38_21520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW38_21525	COG0358	DNA primase activity
EXW38_21535	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW38_21540	COG0517	IMP dehydrogenase activity
EXW38_21545	COG1381	Involved in DNA repair and RecF pathway recombination
EXW38_21555	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW38_21560	COG0295	cytidine deaminase activity
EXW38_21565	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW38_21570	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW38_21575	COG1480	7TM receptor with intracellular HD hydrolase
EXW38_21580	COG1702	phosphate starvation-inducible protein PhoH
EXW38_21595	COG1610	YqeY-like protein
EXW38_21600	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW38_21610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW38_21615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW38_21625	COG0484	heat shock protein binding
EXW38_21630	COG0443	Heat shock 70 kDa protein
EXW38_21640	COG1420	regulation of RNA biosynthetic process
EXW38_21645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW38_21650	COG1733	regulation of RNA biosynthetic process
EXW38_21655	COG0481	GTPase activity
EXW38_21665	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW38_21670	COG0268	Binds directly to 16S ribosomal RNA
EXW38_21675	COG1466	dna polymerase III delta subunit
EXW38_21685	COG2333	competence protein COMEC
EXW38_21685	COG0658	competence protein
EXW38_21690	COG2131	deaminase
EXW38_21700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW38_21705	COG2226	methyltransferase
EXW38_21710	COG0799	negative regulation of ribosome biogenesis
EXW38_21715	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW38_21720	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW38_21725	COG1534	Rna-binding protein
EXW38_21730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW38_21735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW38_21740	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW38_21750	COG0688	phosphatidylethanolamine metabolic process
EXW38_21770	COG2357	RelA SpoT domain protein
EXW38_21780	COG1785	Belongs to the alkaline phosphatase family
EXW38_21790	COG2267	carboxylic ester hydrolase activity
EXW38_21825	COG1404	Belongs to the peptidase S8 family
EXW38_21830	COG3186	Phenylalanine-4-hydroxylase
EXW38_21840	COG2514	catechol 2,3-dioxygenase activity
EXW38_21845	COG2259	Doxx family
EXW38_21885	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW38_21900	COG1454	alcohol dehydrogenase
EXW38_21900	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_21905	COG0626	cystathionine gamma-synthase activity
EXW38_21910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW38_21915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW38_21920	COG2226	methyltransferase
EXW38_21935	COG0768	penicillin binding
EXW38_21945	COG0572	uridine kinase
EXW38_21950	COG0826	peptidase U32
EXW38_21955	COG0826	peptidase U32
EXW38_21960	COG4122	O-methyltransferase activity
EXW38_21965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW38_21975	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW38_21985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW38_21990	COG0628	permease
EXW38_22010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW38_22020	COG0482	sulfurtransferase activity
EXW38_22025	COG1104	cysteine desulfurase activity
EXW38_22030	COG1959	2 iron, 2 sulfur cluster binding
EXW38_22035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW38_22045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW38_22050	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW38_22060	COG1490	D-aminoacyl-tRNA deacylase activity
EXW38_22065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW38_22070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW38_22075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW38_22075	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW38_22080	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW38_22085	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW38_22085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW38_22095	COG2244	polysaccharide biosynthetic process
EXW38_22100	COG2323	membrane
EXW38_22110	COG1862	Preprotein translocase
EXW38_22115	COG0343	queuine tRNA-ribosyltransferase activity
EXW38_22130	COG2255	four-way junction helicase activity
EXW38_22135	COG0632	four-way junction helicase activity
EXW38_22140	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW38_22165	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW38_22170	COG0157	Belongs to the NadC ModD family
EXW38_22175	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW38_22180	COG1104	cysteine desulfurase activity
EXW38_22185	COG1827	regulation of RNA biosynthetic process
EXW38_22190	COG2258	MOSC domain
EXW38_22200	COG0077	Prephenate dehydratase
EXW38_22205	COG0577	efflux transmembrane transporter activity
EXW38_22210	COG0577	efflux transmembrane transporter activity
EXW38_22215	COG1136	(ABC) transporter
EXW38_22220	COG5002	protein histidine kinase activity
EXW38_22225	COG0745	RESPONSE REGULATOR receiver
EXW38_22230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW38_22235	COG3290	protein histidine kinase activity
EXW38_22245	COG2868	ribosomal protein
EXW38_22255	COG1530	ribonuclease E activity
EXW38_22260	COG1994	Peptidase M50
EXW38_22265	COG0739	heme binding
EXW38_22270	COG2894	cell division
EXW38_22275	COG0850	regulation of cytokinetic process
EXW38_22290	COG1077	Cell shape determining protein MreB Mrl
EXW38_22295	COG2003	Belongs to the UPF0758 family
EXW38_22300	COG0424	maF-like protein
EXW38_22315	COG0285	dihydrofolate synthase activity
EXW38_22330	COG1388	LysM domain
EXW38_22335	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW38_22340	COG0113	porphobilinogen synthase activity
EXW38_22345	COG1587	Uroporphyrinogen-III synthase
EXW38_22350	COG0181	hydroxymethylbilane synthase activity
EXW38_22355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW38_22360	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW38_22365	COG1846	Transcriptional regulator
EXW38_22370	COG1764	response to oxidative stress
EXW38_22375	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW38_22385	COG0470	DNA polymerase III
EXW38_22385	COG1067	ATP-dependent peptidase activity
EXW38_22395	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW38_22425	COG0622	Phosphoesterase
EXW38_22435	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW38_22440	COG5401	PFAM Sporulation and spore germination
EXW38_22460	COG2197	response regulator
EXW38_22465	COG2233	PERMEase
EXW38_22470	COG0402	S-adenosylhomocysteine deaminase activity
EXW38_22475	COG1983	PspC domain protein
EXW38_22480	COG1396	sequence-specific DNA binding
EXW38_22485	COG0697	spore germination
EXW38_22495	COG1959	2 iron, 2 sulfur cluster binding
EXW38_22500	COG1668	transmembrane transport
EXW38_22505	COG4152	abc transporter atp-binding protein
EXW38_22510	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW38_22515	COG1360	Flagellar Motor Protein
EXW38_22520	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW38_22525	COG1876	peptidase activity
EXW38_22530	COG0824	Thioesterase
EXW38_22535	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW38_22540	COG1053	succinate dehydrogenase
EXW38_22545	COG2009	succinate dehydrogenase
EXW38_22550	COG1719	4-vinyl reductase, 4VR
EXW38_22555	COG0322	excinuclease ABC activity
EXW38_22560	COG3118	belongs to the thioredoxin family
EXW38_22565	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW38_22570	COG2086	electron transfer activity
EXW38_22575	COG1024	Enoyl-CoA hydratase
EXW38_22580	COG1309	transcriptional regulator
EXW38_22585	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_22610	COG2318	DinB family
EXW38_22635	COG1131	(ABC) transporter
EXW38_22640	COG2205	protein histidine kinase activity
EXW38_22645	COG0745	RESPONSE REGULATOR receiver
EXW38_22650	COG4895	conserved protein (DUF2196)
EXW38_22655	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW38_22665	COG4509	Sortase family
EXW38_22670	COG1120	ATPase activity
EXW38_22685	COG5386	Cell surface protein
EXW38_22690	COG5386	Cell surface protein
EXW38_22695	COG1114	Component of the transport system for branched-chain amino acids
EXW38_22700	COG1187	pseudouridine synthase activity
EXW38_22705	COG1193	negative regulation of DNA recombination
EXW38_22710	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW38_22710	COG1796	DNA polymerase
EXW38_22715	COG1286	toxin biosynthetic process
EXW38_22720	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW38_22725	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW38_22750	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW38_22755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW38_22770	COG1418	mRNA catabolic process
EXW38_22790	COG2814	Major facilitator Superfamily
EXW38_22795	COG1566	PFAM secretion protein HlyD family protein
EXW38_22800	COG1309	transcriptional regulator
EXW38_22805	COG1363	Peptidase, m42
EXW38_22815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW38_22830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW38_22845	COG1484	DNA-dependent DNA replication
EXW38_22850	COG3611	Membrane attachment protein
EXW38_22855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW38_22860	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW38_22870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW38_22880	COG1971	Probably functions as a manganese efflux pump
EXW38_22890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW38_22890	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW38_22895	COG5002	protein histidine kinase activity
EXW38_22900	COG0745	RESPONSE REGULATOR receiver
EXW38_22920	COG0538	isocitrate dehydrogenase activity
EXW38_22925	COG0372	Belongs to the citrate synthase family
EXW38_22940	COG0628	permease
EXW38_22945	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW38_22955	COG0205	6-phosphofructokinase activity
EXW38_22970	COG1725	Transcriptional regulator
EXW38_22975	COG0281	malic enzyme
EXW38_22980	COG0587	DNA-directed DNA polymerase activity
EXW38_22995	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW38_23015	COG4109	DRTGG domain
EXW38_23020	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW38_23025	COG0006	proline dipeptidase activity
EXW38_23075	COG1476	TRANSCRIPTIONal
EXW38_23090	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_23095	COG0589	response to stress
EXW38_23115	COG0165	Argininosuccinate lyase
EXW38_23120	COG0137	argininosuccinate synthase activity
EXW38_23140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_23155	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW38_23160	COG0827	DNA restriction-modification system
EXW38_23165	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW38_23170	COG3874	Sporulation protein YtfJ
EXW38_23185	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW38_23195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW38_23210	COG1104	cysteine desulfurase activity
EXW38_23215	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW38_23230	COG1309	transcriptional regulator
EXW38_23235	COG1956	GAF domain-containing protein
EXW38_23240	COG0626	cystathionine gamma-synthase activity
EXW38_23245	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW38_23270	COG1595	DNA-templated transcription, initiation
EXW38_23280	COG0110	maltose O-acetyltransferase activity
EXW38_23285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW38_23290	COG0454	-acetyltransferase
EXW38_23295	COG0517	IMP dehydrogenase activity
EXW38_23300	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW38_23315	COG0745	RESPONSE REGULATOR receiver
EXW38_23320	COG5002	protein histidine kinase activity
EXW38_23325	COG0666	response to abiotic stimulus
EXW38_23335	COG1970	mechanosensitive ion channel activity
EXW38_23355	COG1609	Transcriptional regulator
EXW38_23360	COG4851	CamS sex pheromone cAM373 precursor
EXW38_23365	COG3118	belongs to the thioredoxin family
EXW38_23375	COG2309	aminopeptidase activity
EXW38_23395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_23400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW38_23410	COG1674	ftsk spoiiie
EXW38_23425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW38_23430	COG4848	Belongs to the UPF0354 family
EXW38_23435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW38_23440	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW38_23445	COG1363	Peptidase, m42
EXW38_23455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_23460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW38_23470	COG0510	thiamine kinase activity
EXW38_23475	COG1523	belongs to the glycosyl hydrolase 13 family
EXW38_23485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW38_23490	COG1349	DNA-binding transcription factor activity
EXW38_23495	COG1187	pseudouridine synthase activity
EXW38_23500	COG2244	polysaccharide biosynthetic process
EXW38_23505	COG2081	HI0933 family
EXW38_23510	COG2814	Major facilitator Superfamily
EXW38_23520	COG3832	glyoxalase III activity
EXW38_23545	COG1329	Transcriptional regulator
EXW38_23560	COG0314	molybdopterin synthase activity
EXW38_23565	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW38_23570	COG0303	'Molybdopterin
EXW38_23575	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW38_23580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW38_23585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW38_23605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW38_23615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW38_23655	COG0495	leucyl-tRNA aminoacylation
EXW38_23660	COG2814	Major facilitator Superfamily
EXW38_23665	COG0475	glutathione-regulated potassium exporter activity
EXW38_23670	COG0490	domain, Protein
EXW38_23675	COG0582	viral genome integration into host DNA
EXW38_23690	COG1136	(ABC) transporter
EXW38_23705	COG1242	4 iron, 4 sulfur cluster binding
EXW38_23710	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW38_23715	COG1794	racemase activity, acting on amino acids and derivatives
EXW38_23740	COG2267	carboxylic ester hydrolase activity
EXW38_23745	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW38_23750	COG0671	phosphoesterase, PA-phosphatase related
EXW38_23755	COG0438	transferase activity, transferring glycosyl groups
EXW38_23765	COG1404	Belongs to the peptidase S8 family
EXW38_23770	COG2197	response regulator
EXW38_23775	COG4585	Histidine kinase
EXW38_23780	COG0746	molybdenum cofactor guanylyltransferase activity
EXW38_23795	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW38_23800	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW38_23835	COG5002	protein histidine kinase activity
EXW38_23840	COG3852	Histidine kinase
EXW38_23845	COG0753	catalase activity
EXW38_23850	COG2267	carboxylic ester hydrolase activity
EXW38_23855	COG1368	sulfuric ester hydrolase activity
EXW38_23860	COG4895	conserved protein (DUF2196)
EXW38_23875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW38_23880	COG1116	anion transmembrane transporter activity
EXW38_23885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW38_23905	COG0494	nUDIX hydrolase
EXW38_23940	COG2723	6-phospho-beta-galactosidase activity
EXW38_23945	COG2723	6-phospho-beta-galactosidase activity
EXW38_23950	COG1263	PTS System
EXW38_23950	COG2190	(PTS) system
EXW38_23950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_23955	COG3711	transcriptional antiterminator
EXW38_23960	COG1854	S-ribosylhomocysteine lyase activity
EXW38_23970	COG0288	reversible hydration of carbon dioxide
EXW38_23975	COG1271	oxidase subunit
EXW38_23980	COG1294	oxidase, subunit
EXW38_23995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_24020	COG1842	Phage shock protein A
EXW38_24045	COG3859	Proton-coupled thiamine transporter YuaJ
EXW38_24050	COG5002	protein histidine kinase activity
EXW38_24055	COG0745	RESPONSE REGULATOR receiver
EXW38_24080	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW38_24085	COG1597	lipid kinase activity
EXW38_24115	COG1136	(ABC) transporter
EXW38_24130	COG5002	protein histidine kinase activity
EXW38_24140	COG0586	Pfam SNARE associated Golgi protein
EXW38_24150	COG0577	efflux transmembrane transporter activity
EXW38_24155	COG1136	(ABC) transporter
EXW38_24160	COG3708	Transcriptional regulator
EXW38_24160	COG2207	Transcriptional regulator
EXW38_24170	COG1131	(ABC) transporter
EXW38_24175	COG5658	integral membrane protein
EXW38_24180	COG0640	Transcriptional regulator
EXW38_24185	COG0745	RESPONSE REGULATOR receiver
EXW38_24190	COG2205	protein histidine kinase activity
EXW38_24195	COG0577	efflux transmembrane transporter activity
EXW38_24200	COG0577	efflux transmembrane transporter activity
EXW38_24205	COG1136	(ABC) transporter
EXW38_24210	COG0577	efflux transmembrane transporter activity
EXW38_24225	COG2188	Transcriptional regulator
EXW38_24245	COG3964	amidohydrolase
EXW38_24265	COG4948	Mandelate Racemase Muconate Lactonizing
EXW38_24270	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_24275	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW38_24280	COG0596	Alpha beta hydrolase
EXW38_24285	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW38_24290	COG1169	isochorismate synthase
EXW38_24295	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW38_24300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW38_24305	COG1278	Cold shock
EXW38_24320	COG1051	belongs to the nudix hydrolase family
EXW38_24335	COG0058	SHG alpha-glucan phosphorylase activity
EXW38_24345	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW38_24350	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW38_24355	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW38_24490	COG1285	pathogenesis
EXW38_24495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW38_24505	COG0166	Belongs to the GPI family
EXW38_24515	COG2155	Conserved Protein
EXW38_24520	COG1098	S1 RNA binding domain
EXW38_24525	COG0436	Aminotransferase
EXW38_24530	COG1522	sequence-specific DNA binding
EXW38_24535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW38_24540	COG2267	carboxylic ester hydrolase activity
EXW38_24550	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW38_24585	COG5018	Exonuclease
EXW38_24590	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW38_24615	COG2050	protein possibly involved in aromatic compounds catabolism
EXW38_24625	COG1268	BioY protein
EXW38_24630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW38_24635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW38_24645	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW38_24650	COG3584	3D domain protein
EXW38_24665	COG1252	NADH dehydrogenase
EXW38_24670	COG0492	ferredoxin-NADP+ reductase activity
EXW38_24675	COG3708	Transcriptional regulator
EXW38_24695	COG1683	Conserved Protein
EXW38_24705	COG0316	Belongs to the HesB IscA family
EXW38_24710	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW38_24715	COG4844	belongs to the
EXW38_24720	COG1252	NADH dehydrogenase
EXW38_24725	COG2274	protein secretion by the type I secretion system
EXW38_24730	COG0390	transport system, permease component
EXW38_24735	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW38_24770	COG4837	Protein of unknown function (DUF1462)
EXW38_24775	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW38_24785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW38_24790	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW38_24805	COG1136	(ABC) transporter
EXW38_24805	COG0577	efflux transmembrane transporter activity
EXW38_24810	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW38_24820	COG0647	UMP catabolic process
EXW38_24830	COG2445	Protein of unknown function DUF86
EXW38_24835	COG1494	fructose-1,6-bisphosphatase
EXW38_24860	COG4470	Protein conserved in bacteria
EXW38_24870	COG0789	Transcriptional regulator
EXW38_24875	COG4377	Putative membrane peptidase family (DUF2324)
EXW38_24900	COG0739	heme binding
EXW38_24910	COG3377	Domain of unknown function (DUF1805)
EXW38_24915	COG0737	Belongs to the 5'-nucleotidase family
EXW38_24920	COG0719	Fe-S assembly protein
EXW38_24925	COG0822	iron-sulfur transferase activity
EXW38_24930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW38_24935	COG0719	Fe-S assembly protein
EXW38_24940	COG0396	ATPase activity
EXW38_24945	COG1464	Belongs to the NlpA lipoprotein family
EXW38_24950	COG1464	Belongs to the NlpA lipoprotein family
EXW38_24955	COG2011	ABC-type metal ion transport system permease component
EXW38_24970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW38_24975	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW38_24980	COG0509	glycine decarboxylation via glycine cleavage system
EXW38_24985	COG1393	Belongs to the ArsC family
EXW38_25020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_25035	COG1960	acyl-CoA dehydrogenase activity
EXW38_25040	COG0183	Belongs to the thiolase family
EXW38_25045	COG1024	Enoyl-CoA hydratase
EXW38_25045	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW38_25055	COG1686	Belongs to the peptidase S11 family
EXW38_25060	COG0506	proline dehydrogenase activity
EXW38_25070	COG0011	TIGRFAM Protein of
EXW38_25075	COG0840	transmembrane signaling receptor activity
EXW38_25085	COG2814	Major facilitator Superfamily
EXW38_25090	COG0531	amino acid
EXW38_25110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_25140	COG0586	Pfam SNARE associated Golgi protein
EXW38_25150	COG1376	ErfK ybiS ycfS ynhG family protein
EXW38_25155	COG0745	RESPONSE REGULATOR receiver
EXW38_25160	COG5002	protein histidine kinase activity
EXW38_25170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW38_25180	COG0840	transmembrane signaling receptor activity
EXW38_25185	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW38_25190	COG3227	Zinc metalloprotease (Elastase)
EXW38_25195	COG1741	Belongs to the pirin family
EXW38_25210	COG0586	Pfam SNARE associated Golgi protein
EXW38_25215	COG0475	glutathione-regulated potassium exporter activity
EXW38_25220	COG0490	domain, Protein
EXW38_25225	COG1115	amino acid carrier protein
EXW38_25230	COG0783	Belongs to the Dps family
EXW38_25240	COG2318	DinB family
EXW38_25245	COG1611	Belongs to the LOG family
EXW38_25255	COG1528	Iron-storage protein
EXW38_25260	COG2311	Membrane
EXW38_25265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_25270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_25275	COG1115	amino acid carrier protein
EXW38_25280	COG2910	NAD(P)H-binding
EXW38_25290	COG0656	L-ascorbic acid biosynthetic process
EXW38_25295	COG2814	Major facilitator Superfamily
EXW38_25300	COG1733	regulation of RNA biosynthetic process
EXW38_25310	COG1252	NADH dehydrogenase
EXW38_25355	COG3655	Transcriptional regulator
EXW38_25370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_25380	COG1733	regulation of RNA biosynthetic process
EXW38_25385	COG1522	sequence-specific DNA binding
EXW38_25390	COG0288	reversible hydration of carbon dioxide
EXW38_25395	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW38_25400	COG2233	PERMEase
EXW38_25425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_25445	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW38_25455	COG0557	exoribonuclease II activity
EXW38_25460	COG1647	Serine aminopeptidase, S33
EXW38_25465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW38_25470	COG1346	cytolysis
EXW38_25495	COG0149	triose-phosphate isomerase activity
EXW38_25500	COG0126	phosphoglycerate kinase activity
EXW38_25505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW38_25520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW38_25545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW38_25560	COG2323	membrane
EXW38_25570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW38_25575	COG1481	regulation of sporulation
EXW38_25580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW38_25585	COG1660	Displays ATPase and GTPase activities
EXW38_25590	COG1051	belongs to the nudix hydrolase family
EXW38_25600	COG0492	ferredoxin-NADP+ reductase activity
EXW38_25605	COG0457	Tetratricopeptide repeat
EXW38_25610	COG0110	maltose O-acetyltransferase activity
EXW38_25615	COG0546	phosphoglycolate phosphatase activity
EXW38_25620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW38_25625	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW38_25630	COG1950	PFAM Membrane protein of
EXW38_25640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW38_25655	COG0789	Transcriptional regulator
EXW38_25690	COG0583	DNA-binding transcription factor activity
EXW38_25695	COG0789	Transcriptional regulator
EXW38_25700	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW38_25705	COG0488	(ABC) transporter
EXW38_25715	COG1132	(ABC) transporter
EXW38_25720	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW38_25725	COG0583	DNA-binding transcription factor activity
EXW38_25730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW38_25735	COG3409	Peptidoglycan-binding domain 1 protein
EXW38_25735	COG0793	Belongs to the peptidase S41A family
EXW38_25740	COG2177	Part of the ABC transporter FtsEX involved in
EXW38_25745	COG2884	Cell division ATP-binding protein ftsE
EXW38_25785	COG1278	Cold shock
EXW38_25790	COG1040	competence protein
EXW38_25795	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW38_25800	COG0791	NLP P60 protein
EXW38_25800	COG1388	LysM domain
EXW38_25805	COG1733	regulation of RNA biosynthetic process
EXW38_25810	COG1307	EDD domain protein, DegV family
EXW38_25815	COG1739	Uncharacterized protein family UPF0029
EXW38_25820	COG1316	TRANSCRIPTIONal
EXW38_25825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW38_25830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW38_25835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW38_25845	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW38_25845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW38_25865	COG1486	melibiose metabolic process
EXW38_25870	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW38_25875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW38_25885	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW38_25895	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW38_25905	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW38_25910	COG1301	dicarboxylic acid transport
EXW38_25925	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW38_25930	COG1271	oxidase subunit
EXW38_25935	COG1294	oxidase, subunit
EXW38_25940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW38_25945	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW38_25950	COG1620	l-lactate permease
EXW38_25960	COG2389	metal-binding protein
EXW38_25975	COG1368	sulfuric ester hydrolase activity
EXW38_25990	COG1388	LysM domain
EXW38_25990	COG0791	NLP P60 protein
EXW38_25995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_26005	COG1215	transferase activity, transferring glycosyl groups
EXW38_26010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW38_26020	COG1388	LysM domain
EXW38_26020	COG3584	3D domain protein
EXW38_26030	COG4715	Zinc finger, swim domain protein
EXW38_26035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW38_26080	COG0577	efflux transmembrane transporter activity
EXW38_26085	COG1136	(ABC) transporter
EXW38_26115	COG0745	RESPONSE REGULATOR receiver
EXW38_26120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW38_26135	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW38_26150	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW38_26160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW38_26180	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW38_26190	COG1682	transport, permease protein
EXW38_26195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW38_26240	COG1609	Transcriptional regulator
EXW38_26255	COG0110	maltose O-acetyltransferase activity
EXW38_26280	COG0739	heme binding
EXW38_26295	COG4555	ABC transporter
EXW38_26300	COG2385	sporulation resulting in formation of a cellular spore
EXW38_26315	COG4836	Membrane
EXW38_26320	COG1007	ATP synthesis coupled electron transport
EXW38_26325	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW38_26330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW38_26335	COG0713	ATP synthesis coupled electron transport
EXW38_26340	COG0839	Belongs to the complex I subunit 6 family
EXW38_26350	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW38_26355	COG0649	NAD binding
EXW38_26360	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW38_26365	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW38_26370	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW38_26375	COG3300	MHYT domain
EXW38_26375	COG5001	Diguanylate cyclase
EXW38_26390	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW38_26395	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW38_26400	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW38_26405	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW38_26415	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW38_26425	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW38_26460	COG0698	ribose 5-phosphate isomerase
EXW38_26470	COG2190	(PTS) system
EXW38_26475	COG2259	Doxx family
EXW38_26480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW38_26495	COG1971	Probably functions as a manganese efflux pump
EXW38_26500	COG0009	L-threonylcarbamoyladenylate synthase
EXW38_26515	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW38_26520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW38_26525	COG1435	thymidine kinase activity
EXW38_26535	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW38_26540	COG1494	fructose-1,6-bisphosphatase
EXW38_26560	COG4821	SIS domain
EXW38_26565	COG0504	CTP synthase activity
EXW38_26585	COG1960	acyl-CoA dehydrogenase activity
EXW38_26590	COG1960	acyl-CoA dehydrogenase activity
EXW38_26595	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW38_26600	COG0183	Belongs to the thiolase family
EXW38_26605	COG2181	nitrate reductase activity
EXW38_26605	COG0247	lactate metabolic process
EXW38_26610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW38_26615	COG4294	response to UV
EXW38_26620	COG3300	MHYT domain
EXW38_26620	COG5001	Diguanylate cyclase
EXW38_26635	COG3227	Zinc metalloprotease (Elastase)
EXW38_26640	COG2197	response regulator
EXW38_26645	COG4585	Histidine kinase
EXW38_26650	COG0842	Transport permease protein
EXW38_26655	COG1131	(ABC) transporter
EXW38_26660	COG0024	Methionine aminopeptidase
EXW38_26665	COG2234	aminopeptidase activity
EXW38_26685	COG4506	Protein conserved in bacteria
EXW38_26690	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW38_26715	COG2814	Major facilitator Superfamily
EXW38_26720	COG0789	Transcriptional regulator
EXW38_26725	COG0584	glycerophosphoryl diester phosphodiesterase
EXW38_26730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW38_26740	COG1994	Peptidase M50
EXW38_26750	COG1078	dGTPase activity
EXW38_26755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_26760	COG1120	ATPase activity
EXW38_26765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_26770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_26775	COG4844	belongs to the
EXW38_26790	COG0280	phosphate acetyltransferase
EXW38_26795	COG3253	May function as heme-dependent peroxidase
EXW38_26805	COG3773	Cell wall hydrolase
EXW38_26815	COG2363	Small membrane protein
EXW38_26825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW38_26830	COG2233	PERMEase
EXW38_26835	COG0561	phosphatase activity
EXW38_26840	COG2814	Major facilitator Superfamily
EXW38_26845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW38_26850	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW38_26855	COG1131	(ABC) transporter
EXW38_26860	COG2755	lipolytic protein G-D-S-L family
EXW38_26865	COG1609	Transcriptional regulator
EXW38_26875	COG0460	homoserine dehydrogenase
EXW38_26880	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW38_26885	COG2873	o-acetylhomoserine
EXW38_26900	COG2197	response regulator
EXW38_26905	COG2203	Gaf domain
EXW38_26905	COG4585	Histidine kinase
EXW38_26910	COG0351	phosphomethylpyrimidine kinase
EXW38_26915	COG3706	GGDEF domain
EXW38_26920	COG2879	small protein
EXW38_26925	COG1966	Carbon starvation protein
EXW38_26930	COG3279	Response regulator of the LytR AlgR family
EXW38_26935	COG0477	Major facilitator Superfamily
EXW38_26965	COG0840	transmembrane signaling receptor activity
EXW38_26975	COG1607	acyl-coa hydrolase
EXW38_26985	COG1216	Glycosyl transferase, family 2
EXW38_26990	COG0488	(ABC) transporter
EXW38_27005	COG0463	Glycosyl transferase, family 2
EXW38_27010	COG1309	transcriptional regulator
EXW38_27015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW38_27020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW38_27020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW38_27025	COG0628	permease
EXW38_27035	COG1380	Effector of murein hydrolase LrgA
EXW38_27040	COG3279	Response regulator of the LytR AlgR family
EXW38_27045	COG3275	phosphorelay sensor kinase activity
EXW38_27050	COG2814	Major facilitator Superfamily
EXW38_27055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW38_27060	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW38_27110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW38_27115	COG1272	protein, Hemolysin III
EXW38_27140	COG1164	Oligoendopeptidase f
EXW38_27155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW38_27165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW38_27170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW38_27175	COG4853	Protein conserved in bacteria
EXW38_27185	COG5002	protein histidine kinase activity
EXW38_27190	COG0745	RESPONSE REGULATOR receiver
EXW38_27220	COG0305	Participates in initiation and elongation during chromosome replication
EXW38_27230	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW38_27235	COG4241	membrane
EXW38_27245	COG0629	single-stranded DNA binding
EXW38_27250	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW38_27255	COG0012	GTP binding
EXW38_27260	COG4481	Protein conserved in bacteria
EXW38_27265	COG0668	transmembrane transport
EXW38_27275	COG1475	DNA binding
EXW38_27280	COG1192	Involved in chromosome partitioning
EXW38_27285	COG1475	DNA binding
EXW38_27295	COG0445	tRNA wobble uridine modification
EXW38_27300	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW38_27305	COG1847	R3H domain protein
EXW38_27310	COG0706	membrane insertase activity
EXW38_27315	COG0594	ribonuclease P activity
EXW38_27320	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW38_27400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW38_27425	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW38_27460	COG0561	phosphatase activity
EXW38_27470	COG1609	Transcriptional regulator
EXW38_27495	COG0494	nUDIX hydrolase
EXW38_27520	COG0739	heme binding
EXW38_27530	COG1595	DNA-templated transcription, initiation
EXW38_27625	COG0456	acetyltransferase
EXW38_27695	COG1278	Cold shock
EXW38_27715	COG0582	viral genome integration into host DNA
EXW38_27735	COG5566	PFAM Mor transcription activator
EXW38_27740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_27785	COG0531	amino acid
EXW38_27795	COG3338	carbonate dehydratase activity
EXW38_27805	COG5002	protein histidine kinase activity
EXW38_27835	COG5002	protein histidine kinase activity
EXW38_27850	COG0583	DNA-binding transcription factor activity
EXW38_27855	COG1741	Belongs to the pirin family
EXW38_27860	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW38_27865	COG3227	Zinc metalloprotease (Elastase)
EXW38_27905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW38_27915	COG2707	UPF0756 membrane protein
EXW38_27925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW38_27930	COG4974	Belongs to the 'phage' integrase family
EXW38_27945	COG0583	DNA-binding transcription factor activity
EXW38_27950	COG4689	acetoacetate decarboxylase
EXW38_27975	COG0531	amino acid
EXW38_27990	COG2318	DinB family
EXW38_27995	COG2378	regulation of single-species biofilm formation
EXW38_28015	COG1309	transcriptional regulator
EXW38_28045	COG3739	integral membrane protein
EXW38_28050	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW38_28055	COG1131	(ABC) transporter
EXW38_28065	COG3655	Transcriptional regulator
EXW38_28100	COG1131	(ABC) transporter
EXW38_28120	COG0825	malonyl-CoA metabolic process
EXW38_28170	COG2814	Major facilitator Superfamily
EXW38_28175	COG0583	DNA-binding transcription factor activity
EXW38_28245	COG3493	citrate carrier protein
EXW38_28250	COG4565	transcriptional regulatory protein
EXW38_28255	COG3290	protein histidine kinase activity
EXW38_28265	COG0745	RESPONSE REGULATOR receiver
EXW38_28295	COG0753	catalase activity
EXW38_28455	COG1192	Involved in chromosome partitioning
EXW38_28605	COG3344	reverse transcriptase
EXW38_28610	COG0741	lytic transglycosylase activity
EXW38_28610	COG0791	NLP P60 protein
EXW38_28655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW38_28670	COG4152	abc transporter atp-binding protein
EXW38_28675	COG1668	transmembrane transport
EXW38_28740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW38_28795	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW38_28795	COG2755	lipolytic protein G-D-S-L family
EXW38_28845	COG0741	lytic transglycosylase activity
EXW38_28910	COG0577	efflux transmembrane transporter activity
EXW38_28910	COG1136	(ABC) transporter
EXW38_28995	COG0494	nUDIX hydrolase
EXW38_29000	COG1401	restriction endodeoxyribonuclease activity
EXW38_29085	COG1074	ATP-dependent DNA helicase activity
EXW38_29085	COG1074	ATP-dependent DNA helicase activity
EXW38_29095	COG0582	viral genome integration into host DNA
EXW38_29100	COG1401	restriction endodeoxyribonuclease activity
EXW38_29100	COG1401	restriction endodeoxyribonuclease activity
EXW38_29110	COG2003	Belongs to the UPF0758 family
EXW38_29135	COG3711	transcriptional antiterminator
EXW38_29140	COG1263	PTS System
EXW38_29140	COG2190	(PTS) system
EXW38_29140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_29145	COG2723	6-phospho-beta-galactosidase activity
EXW38_29190	COG3655	Transcriptional regulator
EXW38_29210	COG0662	Cupin 2, conserved barrel domain protein
EXW38_29310	COG5002	protein histidine kinase activity
EXW38_29395	COG1819	glycosyl
EXW38_29400	COG0156	8-amino-7-oxononanoate synthase activity
EXW38_29405	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW38_29410	COG1136	(ABC) transporter
EXW38_29480	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW38_29505	COG0577	efflux transmembrane transporter activity
EXW38_29510	COG1136	(ABC) transporter
EXW38_29525	COG1396	sequence-specific DNA binding
EXW38_29530	COG0006	proline dipeptidase activity
EXW38_29565	COG0582	viral genome integration into host DNA
EXW38_29600	COG2312	Erythromycin esterase
EXW38_29630	COG1073	alpha beta
EXW38_29700	COG1073	alpha beta
EXW38_29725	COG1876	peptidase activity
EXW38_29760	COG4974	Belongs to the 'phage' integrase family
EXW38_29805	COG2814	Major facilitator Superfamily
EXW38_29810	COG1846	Transcriptional regulator
EXW38_29855	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW38_29870	COG1923	regulation of RNA biosynthetic process
EXW38_29895	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW38_29905	COG0814	amino acid
EXW38_29910	COG1760	l-serine dehydratase
EXW38_29915	COG1760	l-serine dehydratase
EXW38_29925	COG1136	(ABC) transporter
EXW38_29930	COG0500	methyltransferase
EXW38_29930	COG3615	Tellurite resistance protein tehB
EXW38_29995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW38_30015	COG2720	vancomycin resistance protein
EXW38_30035	COG1073	alpha beta
EXW38_30055	COG2318	DinB family
EXW38_30075	COG1309	transcriptional regulator
EXW38_30265	COG0686	Belongs to the AlaDH PNT family
EXW38_30270	COG2508	Transcriptional regulator
EXW38_30270	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW38_30280	COG2814	Major facilitator Superfamily
EXW38_30285	COG1309	transcriptional regulator
EXW38_30295	COG0582	viral genome integration into host DNA
EXW38_30325	COG0825	malonyl-CoA metabolic process
EXW38_30355	COG0662	Cupin 2, conserved barrel domain protein
EXW38_30400	COG1329	Transcriptional regulator
EXW38_30430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW38_30435	COG1011	Hydrolase
EXW38_30475	COG0789	Transcriptional regulator
EXW38_30500	COG0814	amino acid
EXW38_30505	COG0697	spore germination
EXW38_30665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW38_30695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW38_30710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW38_30845	COG0463	Glycosyl transferase, family 2
EXW38_30870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW38_30875	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW38_30880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW38_30885	COG0438	transferase activity, transferring glycosyl groups
EXW38_30910	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW38_30915	COG0438	transferase activity, transferring glycosyl groups
EXW38_30920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW38_31015	COG3773	Cell wall hydrolase
EXW38_31105	COG4166	transmembrane transport
EXW38_31140	COG1192	Involved in chromosome partitioning
EXW38_31165	COG1132	(ABC) transporter
EXW38_31175	COG0582	viral genome integration into host DNA