locus-tag	class	description
EXW50_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW50_00010	COG0592	DNA-directed DNA polymerase activity
EXW50_00015	COG2501	S4 domain
EXW50_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW50_00025	COG0187	DNA topoisomerase II activity
EXW50_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW50_00065	COG0517	IMP dehydrogenase activity
EXW50_00065	COG0516	GMP reductase activity
EXW50_00070	COG1686	Belongs to the peptidase S11 family
EXW50_00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW50_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW50_00100	COG1428	Deoxynucleoside kinase
EXW50_00105	COG1428	Deoxynucleoside kinase
EXW50_00110	COG1335	isochorismatase
EXW50_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW50_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW50_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW50_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW50_00180	COG1982	Orn Lys Arg decarboxylase major
EXW50_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW50_00190	COG0470	DNA polymerase III
EXW50_00195	COG1774	PSP1 C-terminal conserved region
EXW50_00200	COG4467	Involved in initiation control of chromosome replication
EXW50_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW50_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW50_00220	COG2002	toxin-antitoxin pair type II binding
EXW50_00230	COG0084	hydrolase, TatD family'
EXW50_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW50_00250	COG4466	Protein conserved in bacteria
EXW50_00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW50_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW50_00270	COG0251	oxidation-reduction process
EXW50_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW50_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW50_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW50_00305	COG2002	toxin-antitoxin pair type II binding
EXW50_00310	COG2244	polysaccharide biosynthetic process
EXW50_00315	COG3956	TIGRFAM MazG family protein
EXW50_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW50_00340	COG1098	S1 RNA binding domain
EXW50_00355	COG2208	phosphoserine phosphatase activity
EXW50_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW50_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW50_00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW50_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW50_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW50_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW50_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW50_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW50_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW50_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW50_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW50_00420	COG1396	sequence-specific DNA binding
EXW50_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW50_00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW50_00520	COG3880	PFAM UvrB UvrC protein
EXW50_00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW50_00530	COG0542	response to heat
EXW50_00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW50_00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW50_00545	COG4956	integral membrane protein (PIN domain superfamily)
EXW50_00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW50_00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW50_00565	COG1045	serine acetyltransferase
EXW50_00570	COG0215	cysteine-tRNA ligase activity
EXW50_00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW50_00585	COG3688	RNA-binding protein containing a PIN domain
EXW50_00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW50_00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW50_00605	COG0250	Participates in transcription elongation, termination and antitermination
EXW50_00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW50_00615	COG0081	regulation of translation
EXW50_00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW50_00625	COG0222	ribosome binding
EXW50_00630	COG2813	Specifically methylates the guanine in position
EXW50_00635	COG0085	RNA polymerase activity
EXW50_00640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW50_00645	COG1358	cellular component organization or biogenesis
EXW50_00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW50_00660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW50_00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW50_00670	COG0051	transcription antitermination factor activity, RNA binding
EXW50_00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW50_00680	COG0088	Forms part of the polypeptide exit tunnel
EXW50_00685	COG0089	rRNA binding
EXW50_00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW50_00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW50_00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW50_00715	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW50_00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW50_00730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW50_00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW50_00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW50_00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW50_00765	COG1841	ribosomal large subunit assembly
EXW50_00770	COG0200	Binds to the 23S rRNA
EXW50_00775	COG0201	protein transport
EXW50_00780	COG0563	adenylate kinase activity
EXW50_00785	COG0024	Methionine aminopeptidase
EXW50_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW50_00800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW50_00805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW50_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW50_00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW50_00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW50_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW50_00860	COG0489	protein tyrosine kinase activity
EXW50_00870	COG2194	sulfuric ester hydrolase activity
EXW50_00875	COG0726	polysaccharide deacetylase
EXW50_00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW50_00960	COG4856	YbbR-like protein
EXW50_00965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW50_00985	COG4946	Tricorn protease homolog
EXW50_00985	COG1506	peptidase
EXW50_00985	COG0823	Involved in the tonB-independent uptake of proteins
EXW50_01010	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_01015	COG2011	ABC-type metal ion transport system permease component
EXW50_01025	COG1464	Belongs to the NlpA lipoprotein family
EXW50_01040	COG0277	FAD linked oxidase domain protein
EXW50_01045	COG2271	Major facilitator Superfamily
EXW50_01055	COG2814	Major facilitator Superfamily
EXW50_01075	COG0601	transmembrane transport
EXW50_01080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW50_01085	COG0444	Belongs to the ABC transporter superfamily
EXW50_01090	COG4608	Belongs to the ABC transporter superfamily
EXW50_01095	COG4166	transmembrane transport
EXW50_01105	COG2207	Transcriptional regulator
EXW50_01120	COG4166	transmembrane transport
EXW50_01125	COG4166	transmembrane transport
EXW50_01130	COG0656	L-ascorbic acid biosynthetic process
EXW50_01135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW50_01150	COG4149	molybdate abc transporter
EXW50_01155	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW50_01160	COG1910	domain protein
EXW50_01175	COG0697	spore germination
EXW50_01190	COG0204	Acyl-transferase
EXW50_01200	COG1609	Transcriptional regulator
EXW50_01210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW50_01230	COG5298	Protein conserved in bacteria
EXW50_01255	COG0488	(ABC) transporter
EXW50_01265	COG0747	negative chemotaxis
EXW50_01275	COG0601	transmembrane transport
EXW50_01280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW50_01285	COG0444	Belongs to the ABC transporter superfamily
EXW50_01290	COG4608	Belongs to the ABC transporter superfamily
EXW50_01295	COG0561	phosphatase activity
EXW50_01325	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW50_01330	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW50_01340	COG0531	amino acid
EXW50_01345	COG2814	Major facilitator Superfamily
EXW50_01355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW50_01365	COG4294	response to UV
EXW50_01370	COG0705	Rhomboid family
EXW50_01375	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW50_01380	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW50_01385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW50_01390	COG0864	Transcriptional regulator
EXW50_01395	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW50_01400	COG2183	response to ionizing radiation
EXW50_01500	COG0802	atpase or kinase
EXW50_01505	COG1214	PFAM Peptidase M22, glycoprotease
EXW50_01510	COG0456	acetyltransferase
EXW50_01520	COG0488	(ABC) transporter
EXW50_01525	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW50_01535	COG1266	CAAX protease self-immunity
EXW50_01540	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW50_01545	COG0459	protein refolding
EXW50_01550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW50_01550	COG0519	Catalyzes the synthesis of GMP from XMP
EXW50_01555	COG2252	PERMEase
EXW50_01565	COG5002	protein histidine kinase activity
EXW50_01590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW50_01615	COG0693	protein deglycase activity
EXW50_01670	COG2205	protein histidine kinase activity
EXW50_01675	COG0745	RESPONSE REGULATOR receiver
EXW50_01700	COG0697	spore germination
EXW50_01725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW50_01730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW50_01735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW50_01740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW50_01745	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW50_01750	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW50_01755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW50_01760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW50_01765	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW50_01770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW50_01775	COG0138	bifunctional purine biosynthesis protein purh
EXW50_01780	COG0151	Belongs to the GarS family
EXW50_01805	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW50_01810	COG0210	DNA helicase
EXW50_01815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW50_01820	COG4851	CamS sex pheromone cAM373 precursor
EXW50_01830	COG1012	belongs to the aldehyde dehydrogenase family
EXW50_01835	COG1335	isochorismatase
EXW50_01845	COG2011	ABC-type metal ion transport system permease component
EXW50_01850	COG1464	Belongs to the NlpA lipoprotein family
EXW50_01865	COG0003	Pfam Anion-transporting ATPase
EXW50_01870	COG1846	Transcriptional regulator
EXW50_01875	COG4682	membrane
EXW50_01885	COG0154	amidase activity
EXW50_01890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW50_01895	COG1597	lipid kinase activity
EXW50_01900	COG0546	phosphoglycolate phosphatase activity
EXW50_01905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW50_01915	COG1012	belongs to the aldehyde dehydrogenase family
EXW50_01920	COG2076	Multidrug Resistance protein
EXW50_01925	COG2309	aminopeptidase activity
EXW50_01940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW50_01950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW50_01955	COG5002	protein histidine kinase activity
EXW50_01960	COG4807	Protein conserved in bacteria
EXW50_01985	COG1757	Na H antiporter
EXW50_01990	COG1473	amidohydrolase
EXW50_02010	COG0450	alkyl hydroperoxide reductase
EXW50_02020	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW50_02030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW50_02035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW50_02040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW50_02045	COG0492	ferredoxin-NADP+ reductase activity
EXW50_02055	COG0166	Belongs to the GPI family
EXW50_02080	COG5002	protein histidine kinase activity
EXW50_02100	COG3541	Predicted nucleotidyltransferase
EXW50_02105	COG0723	plastoquinol--plastocyanin reductase activity
EXW50_02105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW50_02115	COG0765	amino acid transport
EXW50_02120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW50_02130	COG0840	transmembrane signaling receptor activity
EXW50_02155	COG0549	Belongs to the carbamate kinase family
EXW50_02170	COG0277	FAD linked oxidase domain protein
EXW50_02175	COG0366	Alpha amylase catalytic
EXW50_02180	COG2190	(PTS) system
EXW50_02180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW50_02180	COG1263	PTS System
EXW50_02200	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW50_02210	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW50_02230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW50_02235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW50_02240	COG1116	anion transmembrane transporter activity
EXW50_02245	COG0488	(ABC) transporter
EXW50_02295	COG2270	Major facilitator Superfamily
EXW50_02325	COG2310	stress, protein
EXW50_02330	COG2310	stress, protein
EXW50_02335	COG2310	stress, protein
EXW50_02340	COG0861	Integral membrane protein TerC family
EXW50_02350	COG3853	Toxic anion resistance protein (TelA)
EXW50_02360	COG4840	Belongs to the UPF0435 family
EXW50_02370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW50_02380	COG1295	ribonuclease BN
EXW50_02385	COG2217	Heavy metal translocating P-type atpase
EXW50_02390	COG0697	spore germination
EXW50_02415	COG0586	Pfam SNARE associated Golgi protein
EXW50_02430	COG3871	stress protein (general stress protein 26)
EXW50_02435	COG0387	Pfam Sodium calcium exchanger
EXW50_02445	COG0535	radical SAM domain protein
EXW50_02465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW50_02485	COG3829	transcription factor binding
EXW50_02495	COG0833	amino acid
EXW50_02500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW50_02520	COG2066	Belongs to the glutaminase family
EXW50_02530	COG1263	PTS System
EXW50_02530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW50_02535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW50_02550	COG1216	Glycosyl transferase, family 2
EXW50_02560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW50_02560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW50_02565	COG0463	Glycosyl transferase, family 2
EXW50_02580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW50_02585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW50_02600	COG1228	amidohydrolase
EXW50_02605	COG1090	epimerase
EXW50_02610	COG2137	regulation of response to DNA damage stimulus
EXW50_02635	COG1988	membrane-bound metal-dependent
EXW50_02640	COG1194	a g-specific adenine glycosylase
EXW50_02660	COG3557	Belongs to the UPF0374 family
EXW50_02665	COG1132	(ABC) transporter
EXW50_02670	COG4129	membrane
EXW50_02680	COG0070	glutamate synthase
EXW50_02680	COG0069	glutamate synthase activity
EXW50_02680	COG0067	glutamate synthase
EXW50_02685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW50_02690	COG4555	ABC transporter
EXW50_02710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW50_02715	COG0735	belongs to the Fur family
EXW50_02840	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW50_02845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW50_02865	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW50_02875	COG2766	serine protein kinase
EXW50_02880	COG2718	Belongs to the UPF0229 family
EXW50_02895	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW50_02900	COG2268	Band 7 protein
EXW50_02915	COG3290	protein histidine kinase activity
EXW50_02920	COG4565	transcriptional regulatory protein
EXW50_02925	COG2851	Citrate transporter
EXW50_02950	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW50_02955	COG3842	ATPase activity
EXW50_02960	COG1175	transmembrane transport
EXW50_02965	COG0395	ABC-type sugar transport system, permease component
EXW50_02975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW50_02980	COG0745	RESPONSE REGULATOR receiver
EXW50_02985	COG5002	protein histidine kinase activity
EXW50_02995	COG4990	cell redox homeostasis
EXW50_03005	COG3290	protein histidine kinase activity
EXW50_03010	COG4565	transcriptional regulatory protein
EXW50_03015	COG3493	citrate carrier protein
EXW50_03020	COG0281	malic enzyme
EXW50_03030	COG0697	spore germination
EXW50_03035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW50_03045	COG5002	protein histidine kinase activity
EXW50_03050	COG0745	RESPONSE REGULATOR receiver
EXW50_03055	COG0456	acetyltransferase
EXW50_03060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW50_03065	COG3383	formate dehydrogenase (NAD+) activity
EXW50_03070	COG2427	Protein of unknown function (DUF1641)
EXW50_03085	COG0531	amino acid
EXW50_03095	COG0640	Transcriptional regulator
EXW50_03100	COG2217	Heavy metal translocating P-type atpase
EXW50_03105	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW50_03115	COG3227	Zinc metalloprotease (Elastase)
EXW50_03135	COG2720	vancomycin resistance protein
EXW50_03140	COG1316	TRANSCRIPTIONal
EXW50_03145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW50_03150	COG0346	lactoylglutathione lyase activity
EXW50_03155	COG1253	flavin adenine dinucleotide binding
EXW50_03160	COG1027	Aspartate ammonia-lyase
EXW50_03165	COG1620	l-lactate permease
EXW50_03170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW50_03190	COG3104	oligopeptide transport
EXW50_03195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW50_03200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW50_03205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW50_03220	COG0156	8-amino-7-oxononanoate synthase activity
EXW50_03225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW50_03235	COG4548	von Willebrand factor, type A
EXW50_03240	COG0714	Associated with various cellular activities
EXW50_03260	COG0531	amino acid
EXW50_03265	COG2188	Transcriptional regulator
EXW50_03270	COG1263	PTS System
EXW50_03270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW50_03275	COG0366	Alpha amylase catalytic
EXW50_03290	COG0697	spore germination
EXW50_03300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW50_03305	COG1115	amino acid carrier protein
EXW50_03310	COG1126	abc transporter atp-binding protein
EXW50_03315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW50_03320	COG0765	amino acid transport
EXW50_03325	COG0765	amino acid transport
EXW50_03330	COG0833	amino acid
EXW50_03355	COG2378	regulation of single-species biofilm formation
EXW50_03360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW50_03365	COG5002	protein histidine kinase activity
EXW50_03380	COG0659	secondary active sulfate transmembrane transporter activity
EXW50_03405	COG0601	transmembrane transport
EXW50_03410	COG4608	Belongs to the ABC transporter superfamily
EXW50_03420	COG2271	Major facilitator Superfamily
EXW50_03425	COG1846	Transcriptional regulator
EXW50_03430	COG0477	Major facilitator Superfamily
EXW50_03435	COG1609	Transcriptional regulator
EXW50_03440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW50_03445	COG1869	D-ribose catabolic process
EXW50_03455	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW50_03460	COG1879	ABC-type sugar transport system periplasmic component
EXW50_03490	COG1063	alcohol dehydrogenase
EXW50_03535	COG0840	transmembrane signaling receptor activity
EXW50_03540	COG3583	domain protein
EXW50_03540	COG3584	3D domain protein
EXW50_03545	COG1476	TRANSCRIPTIONal
EXW50_03565	COG3104	oligopeptide transport
EXW50_03570	COG1114	Component of the transport system for branched-chain amino acids
EXW50_03585	COG1113	amino acid transport
EXW50_03590	COG2252	PERMEase
EXW50_03595	COG3620	sequence-specific DNA binding
EXW50_03615	COG0569	domain protein
EXW50_03615	COG0475	glutathione-regulated potassium exporter activity
EXW50_03630	COG1845	cytochrome c oxidase, subunit III
EXW50_03635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW50_03645	COG0833	amino acid
EXW50_03650	COG4990	cell redox homeostasis
EXW50_03665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW50_03670	COG0697	spore germination
EXW50_03675	COG0531	amino acid
EXW50_03685	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW50_03690	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW50_03700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW50_03705	COG0573	inorganic phosphate transmembrane transporter activity
EXW50_03710	COG0581	inorganic phosphate transmembrane transporter activity
EXW50_03720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW50_03840	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW50_03860	COG3103	Sh3 type 3 domain protein
EXW50_03860	COG4991	sh3 domain protein
EXW50_03860	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW50_03865	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW50_03870	COG1116	anion transmembrane transporter activity
EXW50_03875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW50_03880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW50_03885	COG0352	thiamine-phosphate diphosphorylase activity
EXW50_03890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW50_03895	COG2104	thiamine diphosphate biosynthetic process
EXW50_03900	COG2022	thiamine diphosphate biosynthetic process
EXW50_03905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW50_03910	COG0351	phosphomethylpyrimidine kinase
EXW50_03930	COG1136	(ABC) transporter
EXW50_03960	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW50_03965	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW50_03970	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW50_03975	COG2205	protein histidine kinase activity
EXW50_03980	COG2814	Major facilitator Superfamily
EXW50_03985	COG1846	Transcriptional regulator
EXW50_04005	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW50_04010	COG1129	ABC transporter
EXW50_04015	COG1879	ABC-type sugar transport system periplasmic component
EXW50_04020	COG2252	PERMEase
EXW50_04025	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_04085	COG0778	Nitroreductase
EXW50_04090	COG2719	SpoVR family
EXW50_04115	COG1937	Protein conserved in bacteria
EXW50_04120	COG0425	Belongs to the sulfur carrier protein TusA family
EXW50_04120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW50_04125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW50_04125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW50_04130	COG0425	Belongs to the sulfur carrier protein TusA family
EXW50_04135	COG0425	Belongs to the sulfur carrier protein TusA family
EXW50_04135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW50_04140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW50_04145	COG2210	Belongs to the sulfur carrier protein TusA family
EXW50_04150	COG0730	response to heat
EXW50_04160	COG1316	TRANSCRIPTIONal
EXW50_04180	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW50_04185	COG0604	alcohol dehydrogenase
EXW50_04190	COG2814	Major facilitator Superfamily
EXW50_04205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW50_04205	COG3711	transcriptional antiterminator
EXW50_04210	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW50_04215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW50_04240	COG1388	LysM domain
EXW50_04240	COG3584	3D domain protein
EXW50_04245	COG0577	efflux transmembrane transporter activity
EXW50_04250	COG1136	(ABC) transporter
EXW50_04260	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW50_04275	COG1114	Component of the transport system for branched-chain amino acids
EXW50_04280	COG3546	catalase activity
EXW50_04310	COG0586	Pfam SNARE associated Golgi protein
EXW50_04340	COG0531	amino acid
EXW50_04345	COG0475	glutathione-regulated potassium exporter activity
EXW50_04355	COG1737	Transcriptional regulator
EXW50_04365	COG1263	PTS System
EXW50_04365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW50_04375	COG2259	Doxx family
EXW50_04400	COG1522	sequence-specific DNA binding
EXW50_04425	COG2076	Multidrug Resistance protein
EXW50_04430	COG1309	transcriptional regulator
EXW50_04435	COG2814	Major facilitator Superfamily
EXW50_04440	COG1733	regulation of RNA biosynthetic process
EXW50_04455	COG4533	DNA binding
EXW50_04460	COG2211	Major facilitator Superfamily
EXW50_04480	COG0531	amino acid
EXW50_04485	COG1012	belongs to the aldehyde dehydrogenase family
EXW50_04500	COG1132	(ABC) transporter
EXW50_04505	COG1132	(ABC) transporter
EXW50_04510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW50_04515	COG0765	amino acid transport
EXW50_04520	COG1126	abc transporter atp-binding protein
EXW50_04535	COG0189	ligase activity
EXW50_04545	COG4399	Belongs to the UPF0754 family
EXW50_04550	COG3679	Belongs to the UPF0342 family
EXW50_04565	COG0028	Belongs to the TPP enzyme family
EXW50_04570	COG3527	Alpha-acetolactate decarboxylase
EXW50_04575	COG0463	Glycosyl transferase, family 2
EXW50_04580	COG1216	Glycosyl transferase, family 2
EXW50_04585	COG2094	Belongs to the DNA glycosylase MPG family
EXW50_04590	COG0561	phosphatase activity
EXW50_04600	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW50_04600	COG3409	Peptidoglycan-binding domain 1 protein
EXW50_04605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW50_04610	COG0318	PFAM AMP-dependent synthetase and ligase
EXW50_04620	COG0659	secondary active sulfate transmembrane transporter activity
EXW50_04625	COG2244	polysaccharide biosynthetic process
EXW50_04645	COG1024	Enoyl-CoA hydratase
EXW50_04675	COG1363	Peptidase, m42
EXW50_04690	COG2318	DinB family
EXW50_04710	COG0579	oxidoreductase
EXW50_04730	COG2197	response regulator
EXW50_04755	COG0601	transmembrane transport
EXW50_04760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW50_04765	COG0444	Belongs to the ABC transporter superfamily
EXW50_04770	COG4608	Belongs to the ABC transporter superfamily
EXW50_04795	COG0477	Major facilitator Superfamily
EXW50_04800	COG3290	protein histidine kinase activity
EXW50_04805	COG4565	transcriptional regulatory protein
EXW50_04810	COG3181	Tripartite tricarboxylate transporter family receptor
EXW50_04855	COG4978	Transcriptional regulator
EXW50_04855	COG0789	Transcriptional regulator
EXW50_04870	COG0305	Participates in initiation and elongation during chromosome replication
EXW50_04905	COG1842	Phage shock protein A
EXW50_04915	COG0477	Major facilitator Superfamily
EXW50_04965	COG2814	Major facilitator Superfamily
EXW50_04970	COG0640	Transcriptional regulator
EXW50_04995	COG2376	Dihydroxyacetone kinase
EXW50_05015	COG2376	Dihydroxyacetone kinase
EXW50_05030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW50_05035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW50_05075	COG1959	2 iron, 2 sulfur cluster binding
EXW50_05095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW50_05110	COG0457	Tetratricopeptide repeat
EXW50_05120	COG2373	Large extracellular alpha-helical protein
EXW50_05175	COG0825	malonyl-CoA metabolic process
EXW50_05200	COG2807	transmembrane transport
EXW50_05205	COG2186	Transcriptional regulator
EXW50_05220	COG4585	Histidine kinase
EXW50_05225	COG2197	response regulator
EXW50_05255	COG0420	3'-5' exonuclease activity
EXW50_05260	COG4717	serine-type aminopeptidase activity
EXW50_05265	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW50_05275	COG0346	lactoylglutathione lyase activity
EXW50_05280	COG0346	lactoylglutathione lyase activity
EXW50_05285	COG0457	Tetratricopeptide repeat
EXW50_05295	COG2267	carboxylic ester hydrolase activity
EXW50_05305	COG3620	sequence-specific DNA binding
EXW50_05310	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW50_05315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW50_05320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW50_05325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW50_05330	COG1695	Transcriptional regulator
EXW50_05350	COG1595	DNA-templated transcription, initiation
EXW50_05365	COG3973	AAA domain
EXW50_05370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW50_05395	COG0537	adenosine 5'-monophosphoramidase activity
EXW50_05400	COG1131	(ABC) transporter
EXW50_05405	COG4473	ABC transporter
EXW50_05415	COG0247	lactate metabolic process
EXW50_05420	COG1139	Iron-sulfur cluster binding protein
EXW50_05425	COG1556	Lactate utilization protein
EXW50_05445	COG3402	PFAM membrane-flanked domain
EXW50_05450	COG3428	Bacterial PH domain
EXW50_05490	COG3402	PFAM membrane-flanked domain
EXW50_05495	COG3428	Bacterial PH domain
EXW50_05500	COG2329	Antibiotic biosynthesis monooxygenase
EXW50_05505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW50_05510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW50_05515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW50_05520	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW50_05540	COG1309	transcriptional regulator
EXW50_05545	COG1511	domain protein
EXW50_05580	COG1609	Transcriptional regulator
EXW50_05590	COG1234	tRNA 3'-trailer cleavage
EXW50_05595	COG0095	Lipoate-protein ligase
EXW50_05605	COG0318	PFAM AMP-dependent synthetase and ligase
EXW50_05620	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW50_05630	COG4208	sulfate ABC transporter
EXW50_05645	COG1408	metallophosphoesterase
EXW50_05650	COG1078	dGTPase activity
EXW50_05665	COG1595	DNA-templated transcription, initiation
EXW50_05675	COG3708	Transcriptional regulator
EXW50_05675	COG2207	Transcriptional regulator
EXW50_05680	COG2205	protein histidine kinase activity
EXW50_05685	COG0745	RESPONSE REGULATOR receiver
EXW50_05705	COG0501	Belongs to the peptidase M48B family
EXW50_05710	COG0840	transmembrane signaling receptor activity
EXW50_05715	COG0697	spore germination
EXW50_05720	COG3693	PFAM glycoside hydrolase, family 10
EXW50_05725	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW50_05730	COG2224	Isocitrate lyase
EXW50_05740	COG1278	Cold shock
EXW50_05760	COG4903	ComK protein
EXW50_05765	COG0398	Pfam SNARE associated Golgi protein
EXW50_05775	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW50_05780	COG1074	ATP-dependent DNA helicase activity
EXW50_05830	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW50_05855	COG0367	asparagine synthase
EXW50_05875	COG0753	catalase activity
EXW50_05880	COG0004	ammonium transporteR
EXW50_05890	COG1666	GTP binding
EXW50_05895	COG2996	Protein conserved in bacteria
EXW50_05910	COG1329	Transcriptional regulator
EXW50_05945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW50_05955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW50_05970	COG0561	phosphatase activity
EXW50_05990	COG2267	carboxylic ester hydrolase activity
EXW50_06005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW50_06010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW50_06015	COG5504	Zn-dependent protease
EXW50_06035	COG0180	Tryptophanyl-tRNA synthetase
EXW50_06050	COG4166	transmembrane transport
EXW50_06055	COG0601	transmembrane transport
EXW50_06060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW50_06065	COG0444	Belongs to the ABC transporter superfamily
EXW50_06070	COG4608	Belongs to the ABC transporter superfamily
EXW50_06075	COG0534	Mate efflux family protein
EXW50_06080	COG4166	transmembrane transport
EXW50_06100	COG0861	Integral membrane protein TerC family
EXW50_06105	COG4862	establishment of competence for transformation
EXW50_06110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW50_06120	COG1164	Oligoendopeptidase f
EXW50_06130	COG2346	COG2346, Truncated hemoglobins
EXW50_06135	COG4116	CYTH
EXW50_06145	COG2357	RelA SpoT domain protein
EXW50_06155	COG0564	pseudouridine synthase activity
EXW50_06170	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW50_06175	COG0772	Belongs to the SEDS family
EXW50_06180	COG1216	Glycosyl transferase, family 2
EXW50_06200	COG0457	Tetratricopeptide repeat
EXW50_06200	COG0463	Glycosyl transferase, family 2
EXW50_06220	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW50_06235	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW50_06280	COG2153	protein acetylation
EXW50_06285	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW50_06290	COG2382	esterase
EXW50_06315	COG5492	domain, Protein
EXW50_06320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW50_06335	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW50_06335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW50_06340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW50_06345	COG0134	indole-3-glycerol-phosphate synthase activity
EXW50_06350	COG0135	phosphoribosylanthranilate isomerase activity
EXW50_06355	COG0133	tryptophan synthase activity
EXW50_06360	COG0159	tryptophan synthase activity
EXW50_06370	COG1620	l-lactate permease
EXW50_06375	COG5634	Uncharacterized conserved protein (DUF2278)
EXW50_06435	COG2226	methyltransferase
EXW50_06455	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW50_06460	COG0567	Dehydrogenase, E1 component
EXW50_06465	COG1476	TRANSCRIPTIONal
EXW50_06490	COG4152	abc transporter atp-binding protein
EXW50_06495	COG1668	transmembrane transport
EXW50_06535	COG0582	viral genome integration into host DNA
EXW50_06575	COG1686	Belongs to the peptidase S11 family
EXW50_06580	COG0681	Belongs to the peptidase S26 family
EXW50_06615	COG1012	belongs to the aldehyde dehydrogenase family
EXW50_06625	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW50_06630	COG1177	transmembrane transport
EXW50_06635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW50_06645	COG2409	Drug exporters of the RND superfamily
EXW50_06655	COG0564	pseudouridine synthase activity
EXW50_06665	COG2340	Cysteine-rich secretory protein family
EXW50_06670	COG0247	lactate metabolic process
EXW50_06675	COG0277	FAD linked oxidase domain protein
EXW50_06680	COG3835	regulator
EXW50_06690	COG0745	RESPONSE REGULATOR receiver
EXW50_06695	COG5002	protein histidine kinase activity
EXW50_06700	COG2186	Transcriptional regulator
EXW50_06705	COG0247	lactate metabolic process
EXW50_06710	COG1139	Iron-sulfur cluster binding protein
EXW50_06715	COG1556	Lactate utilization protein
EXW50_06720	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW50_06730	COG2116	formate transmembrane transporter activity
EXW50_06735	COG0861	Integral membrane protein TerC family
EXW50_06740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW50_06750	COG2030	dehydratase
EXW50_06770	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_06775	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW50_06785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW50_06800	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW50_06805	COG3842	ATPase activity
EXW50_06820	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW50_06830	COG1349	DNA-binding transcription factor activity
EXW50_06840	COG0235	Class ii aldolase
EXW50_06850	COG2861	carbohydrate metabolic process
EXW50_06860	COG3852	Histidine kinase
EXW50_06865	COG1846	Transcriptional regulator
EXW50_06875	COG2318	DinB family
EXW50_06880	COG5002	protein histidine kinase activity
EXW50_06885	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW50_06890	COG0720	synthase
EXW50_06900	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW50_06905	COG4873	Protein conserved in bacteria
EXW50_06915	COG0456	acetyltransferase
EXW50_06935	COG1780	Probably involved in ribonucleotide reductase function
EXW50_06950	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW50_06955	COG0531	amino acid
EXW50_06960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW50_06975	COG2204	response regulator
EXW50_06980	COG1012	belongs to the aldehyde dehydrogenase family
EXW50_06990	COG1725	Transcriptional regulator
EXW50_06995	COG1131	(ABC) transporter
EXW50_07005	COG1131	(ABC) transporter
EXW50_07010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW50_07015	COG1266	CAAX protease self-immunity
EXW50_07025	COG1522	sequence-specific DNA binding
EXW50_07035	COG1335	isochorismatase
EXW50_07045	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW50_07050	COG2070	2-Nitropropane dioxygenase
EXW50_07055	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW50_07060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW50_07065	COG1696	Membrane protein involved in D-alanine export
EXW50_07070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW50_07085	COG0716	FMN binding
EXW50_07110	COG0534	Mate efflux family protein
EXW50_07135	COG1846	Transcriptional regulator
EXW50_07145	COG1301	dicarboxylic acid transport
EXW50_07150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW50_07160	COG3874	Sporulation protein YtfJ
EXW50_07180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW50_07185	COG0028	Belongs to the TPP enzyme family
EXW50_07190	COG0440	acetolactate synthase activity
EXW50_07200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW50_07210	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW50_07220	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW50_07225	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW50_07235	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW50_07240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW50_07245	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW50_07250	COG0107	imidazoleglycerol-phosphate synthase activity
EXW50_07260	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW50_07265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW50_07280	COG1183	phosphatidylcholine synthase activity
EXW50_07285	COG1368	sulfuric ester hydrolase activity
EXW50_07295	COG0019	diaminopimelate decarboxylase activity
EXW50_07305	COG0175	sulfate reduction
EXW50_07310	COG2046	Belongs to the sulfate adenylyltransferase family
EXW50_07315	COG0529	Catalyzes the synthesis of activated sulfate
EXW50_07320	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW50_07340	COG1648	precorrin-2 dehydrogenase activity
EXW50_07345	COG0733	neurotransmitter:sodium symporter activity
EXW50_07365	COG1757	Na H antiporter
EXW50_07385	COG4758	membrane
EXW50_07390	COG4585	Histidine kinase
EXW50_07395	COG2197	response regulator
EXW50_07405	COG1114	Component of the transport system for branched-chain amino acids
EXW50_07415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW50_07460	COG0730	response to heat
EXW50_07465	COG0306	phosphate transporter
EXW50_07470	COG1392	Phosphate transport regulator
EXW50_07475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW50_07490	COG3852	Histidine kinase
EXW50_07495	COG1801	Protein of unknown function DUF72
EXW50_07505	COG0582	viral genome integration into host DNA
EXW50_07510	COG5002	protein histidine kinase activity
EXW50_07525	COG0392	lysyltransferase activity
EXW50_07525	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW50_07540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW50_07545	COG1686	Belongs to the peptidase S11 family
EXW50_07550	COG2715	membrane protein required for spore maturation
EXW50_07555	COG0700	Nucleoside recognition
EXW50_07560	COG1187	pseudouridine synthase activity
EXW50_07570	COG1333	cytochrome c biogenesis protein
EXW50_07575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW50_07580	COG0745	RESPONSE REGULATOR receiver
EXW50_07585	COG5002	protein histidine kinase activity
EXW50_07590	COG2096	Adenosyltransferase
EXW50_07595	COG4942	peptidase
EXW50_07605	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW50_07610	COG1141	Ferredoxin
EXW50_07620	COG4955	Helix-turn-helix domain
EXW50_07625	COG0514	ATP-dependent DNA helicase (RecQ)
EXW50_07630	COG1266	CAAX protease self-immunity
EXW50_07640	COG1408	metallophosphoesterase
EXW50_07655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW50_07675	COG0492	ferredoxin-NADP+ reductase activity
EXW50_07680	COG0252	asparaginase activity
EXW50_07685	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW50_07695	COG1304	FMN binding
EXW50_07725	COG1160	GTP binding
EXW50_07730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW50_07750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW50_07760	COG0302	gtp cyclohydrolase
EXW50_07765	COG0142	geranyltranstransferase activity
EXW50_07770	COG2226	methyltransferase
EXW50_07775	COG0142	geranyltranstransferase activity
EXW50_07790	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW50_07800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW50_07805	COG0457	Tetratricopeptide repeat
EXW50_07810	COG5582	Belongs to the UPF0302 family
EXW50_07825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW50_07840	COG4347	Protein of unknown function (DUF1405)
EXW50_07855	COG2738	Putative neutral zinc metallopeptidase
EXW50_07865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW50_07870	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW50_07875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW50_07880	COG1803	Methylglyoxal synthase
EXW50_07885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW50_07890	COG0438	transferase activity, transferring glycosyl groups
EXW50_07895	COG0617	tRNA 3'-terminal CCA addition
EXW50_07905	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW50_07910	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW50_07920	COG1199	ATP-dependent helicase activity
EXW50_07920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW50_07940	COG3935	DnaD domain protein
EXW50_07945	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW50_07955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW50_07955	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW50_07960	COG3331	DNA recombination
EXW50_07995	COG4474	Belongs to the UPF0398 family
EXW50_08000	COG3599	regulation of cell shape
EXW50_08010	COG0116	Belongs to the methyltransferase superfamily
EXW50_08020	COG1199	ATP-dependent helicase activity
EXW50_08025	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW50_08035	COG0024	Methionine aminopeptidase
EXW50_08045	COG2233	PERMEase
EXW50_08050	COG2311	Membrane
EXW50_08060	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW50_08070	COG0456	acetyltransferase
EXW50_08120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW50_08135	COG0454	-acetyltransferase
EXW50_08155	COG0328	RNA-DNA hybrid ribonuclease activity
EXW50_08190	COG3403	YqcI/YcgG family
EXW50_08195	COG1280	lysine exporter protein (LysE YggA)
EXW50_08210	COG3162	membrane
EXW50_08215	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW50_08220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW50_08230	COG0475	glutathione-regulated potassium exporter activity
EXW50_08235	COG0789	Transcriptional regulator
EXW50_08235	COG4978	Transcriptional regulator
EXW50_08240	COG0534	Mate efflux family protein
EXW50_08245	COG2323	membrane
EXW50_08250	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW50_08275	COG2814	Major facilitator Superfamily
EXW50_08295	COG1923	regulation of RNA biosynthetic process
EXW50_08305	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW50_08310	COG1360	Flagellar Motor Protein
EXW50_08315	COG2201	protein-glutamate methylesterase activity
EXW50_08320	COG2198	Histidine kinase
EXW50_08320	COG0643	Histidine kinase
EXW50_08325	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW50_08325	COG1776	CheC inhibitor of MCP methylation
EXW50_08340	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW50_08360	COG1256	bacterial-type flagellum assembly
EXW50_08365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW50_08385	COG1815	bacterial-type flagellum-dependent cell motility
EXW50_08390	COG1558	bacterial-type flagellum-dependent cell motility
EXW50_08400	COG1766	The M ring may be actively involved in energy transduction
EXW50_08405	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW50_08415	COG1157	protein secretion by the type III secretion system
EXW50_08435	COG1749	Flagellar hook protein flgE
EXW50_08450	COG0784	Response regulator, receiver
EXW50_08450	COG0835	chemotaxis
EXW50_08475	COG0861	Integral membrane protein TerC family
EXW50_08485	COG3383	formate dehydrogenase (NAD+) activity
EXW50_08490	COG2427	Protein of unknown function (DUF1641)
EXW50_08495	COG5609	conserved protein (DUF2294)
EXW50_08500	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW50_08510	COG2116	formate transmembrane transporter activity
EXW50_08515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW50_08520	COG0303	'Molybdopterin
EXW50_08525	COG0314	molybdopterin synthase activity
EXW50_08540	COG0489	protein tyrosine kinase activity
EXW50_08545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW50_08595	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW50_08600	COG0741	lytic transglycosylase activity
EXW50_08610	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW50_08615	COG1776	CheC inhibitor of MCP methylation
EXW50_08615	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW50_08625	COG1338	Plays a role in the flagellum-specific transport system
EXW50_08630	COG1987	bacterial-type flagellum assembly
EXW50_08640	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW50_08645	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW50_08650	COG1419	protein localization to endoplasmic reticulum
EXW50_08655	COG4786	Flagellar basal body rod
EXW50_08670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW50_08710	COG0412	Dienelactone hydrolase
EXW50_08715	COG2329	Antibiotic biosynthesis monooxygenase
EXW50_08740	COG0583	DNA-binding transcription factor activity
EXW50_08745	COG3842	ATPase activity
EXW50_08795	COG0406	alpha-ribazole phosphatase activity
EXW50_08825	COG0367	asparagine synthase
EXW50_08855	COG1802	Transcriptional regulator
EXW50_08860	COG0697	spore germination
EXW50_08865	COG0438	transferase activity, transferring glycosyl groups
EXW50_08865	COG1216	Glycosyl transferase, family 2
EXW50_08870	COG1757	Na H antiporter
EXW50_08895	COG0534	Mate efflux family protein
EXW50_08900	COG3340	Belongs to the peptidase S51 family
EXW50_08920	COG0785	Cytochrome C biogenesis protein
EXW50_08925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW50_08940	COG3048	D-serine ammonia-lyase activity
EXW50_08945	COG2733	membrane
EXW50_08985	COG1131	(ABC) transporter
EXW50_09005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW50_09010	COG0528	UMP kinase activity
EXW50_09020	COG1027	Aspartate ammonia-lyase
EXW50_09025	COG0281	malic enzyme
EXW50_09030	COG4191	Histidine kinase
EXW50_09035	COG0784	Response regulator, receiver
EXW50_09040	COG1846	Transcriptional regulator
EXW50_09050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW50_09065	COG2502	aspartate--ammonia ligase
EXW50_09070	COG3620	sequence-specific DNA binding
EXW50_09135	COG1695	Transcriptional regulator
EXW50_09150	COG0477	Major facilitator Superfamily
EXW50_09160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW50_09170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW50_09175	COG2223	nitrite transmembrane transporter activity
EXW50_09180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW50_09195	COG2244	polysaccharide biosynthetic process
EXW50_09200	COG0733	neurotransmitter:sodium symporter activity
EXW50_09210	COG5566	PFAM Mor transcription activator
EXW50_09215	COG2323	membrane
EXW50_09235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW50_09240	COG2132	Multicopper oxidase
EXW50_09250	COG5002	protein histidine kinase activity
EXW50_09255	COG0745	RESPONSE REGULATOR receiver
EXW50_09265	COG0129	dihydroxy-acid dehydratase activity
EXW50_09270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW50_09295	COG2814	Major facilitator Superfamily
EXW50_09300	COG3384	dioxygenase
EXW50_09335	COG1073	alpha beta
EXW50_09340	COG4166	transmembrane transport
EXW50_09345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW50_09350	COG0745	RESPONSE REGULATOR receiver
EXW50_09365	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW50_09370	COG1054	Belongs to the UPF0176 family
EXW50_09380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW50_09385	COG0531	amino acid
EXW50_09420	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW50_09435	COG4257	antibiotic catabolic process
EXW50_09440	COG2390	Transcriptional regulator
EXW50_09450	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW50_09455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW50_09460	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW50_09475	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW50_09490	COG0583	DNA-binding transcription factor activity
EXW50_09505	COG0006	proline dipeptidase activity
EXW50_09510	COG2132	Multicopper oxidase
EXW50_09525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW50_09545	COG1114	Component of the transport system for branched-chain amino acids
EXW50_09555	COG1276	copper resistance
EXW50_09555	COG2372	response to copper ion
EXW50_09560	COG4549	nuclear export factor GLE1
EXW50_09570	COG0697	spore germination
EXW50_09575	COG0583	DNA-binding transcription factor activity
EXW50_09580	COG1959	2 iron, 2 sulfur cluster binding
EXW50_09585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW50_09590	COG0778	Nitroreductase
EXW50_09600	COG0628	permease
EXW50_09615	COG1231	oxidoreductase activity
EXW50_09620	COG0523	cobalamin synthesis protein
EXW50_09630	COG0411	ABC transporter
EXW50_09650	COG0583	DNA-binding transcription factor activity
EXW50_09660	COG1942	4-Oxalocrotonate Tautomerase
EXW50_09675	COG0346	lactoylglutathione lyase activity
EXW50_09685	COG1271	oxidase subunit
EXW50_09690	COG1294	oxidase, subunit
EXW50_09695	COG4988	ABC transporter
EXW50_09700	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW50_09725	COG1686	Belongs to the peptidase S11 family
EXW50_09740	COG0791	NLP P60 protein
EXW50_09740	COG1388	LysM domain
EXW50_09750	COG1132	(ABC) transporter
EXW50_09755	COG0745	RESPONSE REGULATOR receiver
EXW50_09760	COG5002	protein histidine kinase activity
EXW50_09765	COG0300	oxidoreductase activity
EXW50_09770	COG4122	O-methyltransferase activity
EXW50_09790	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EXW50_09800	COG0460	homoserine dehydrogenase
EXW50_09810	COG0083	homoserine kinase activity
EXW50_09825	COG1316	TRANSCRIPTIONal
EXW50_09840	COG1285	pathogenesis
EXW50_09845	COG1247	-acetyltransferase
EXW50_09865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW50_09875	COG1082	Xylose isomerase domain protein TIM barrel
EXW50_09885	COG2814	Major facilitator Superfamily
EXW50_09890	COG1279	arginine transmembrane transporter activity
EXW50_09895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW50_09905	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW50_09935	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW50_09940	COG0577	efflux transmembrane transporter activity
EXW50_09945	COG2002	toxin-antitoxin pair type II binding
EXW50_09950	COG1404	Belongs to the peptidase S8 family
EXW50_09955	COG0640	Transcriptional regulator
EXW50_09960	COG0667	Aldo Keto reductase
EXW50_10005	COG3949	Membrane
EXW50_10010	COG0783	Belongs to the Dps family
EXW50_10025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW50_10035	COG1231	oxidoreductase activity
EXW50_10040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW50_10045	COG4989	oxidoreductase activity
EXW50_10050	COG0523	cobalamin synthesis protein
EXW50_10055	COG0456	acetyltransferase
EXW50_10060	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW50_10085	COG1136	(ABC) transporter
EXW50_10090	COG0577	efflux transmembrane transporter activity
EXW50_10095	COG0745	RESPONSE REGULATOR receiver
EXW50_10100	COG2205	protein histidine kinase activity
EXW50_10105	COG1902	pentaerythritol trinitrate reductase activity
EXW50_10110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW50_10120	COG4166	transmembrane transport
EXW50_10125	COG0346	lactoylglutathione lyase activity
EXW50_10135	COG0406	alpha-ribazole phosphatase activity
EXW50_10145	COG5337	Spore coat protein CotH
EXW50_10150	COG1051	belongs to the nudix hydrolase family
EXW50_10155	COG0586	Pfam SNARE associated Golgi protein
EXW50_10160	COG2244	polysaccharide biosynthetic process
EXW50_10170	COG0701	Predicted permease
EXW50_10175	COG3689	TIGRFAM TIGR03943 family protein
EXW50_10180	COG1607	acyl-coa hydrolase
EXW50_10190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW50_10205	COG0702	epimerase
EXW50_10210	COG2839	Protein conserved in bacteria
EXW50_10215	COG1253	flavin adenine dinucleotide binding
EXW50_10240	COG1114	Component of the transport system for branched-chain amino acids
EXW50_10245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW50_10265	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW50_10280	COG1876	peptidase activity
EXW50_10285	COG0494	nUDIX hydrolase
EXW50_10295	COG2211	Major facilitator Superfamily
EXW50_10310	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW50_10320	COG0561	phosphatase activity
EXW50_10325	COG1846	Transcriptional regulator
EXW50_10330	COG2814	Major facilitator Superfamily
EXW50_10340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW50_10345	COG4106	trans-aconitate 2-methyltransferase activity
EXW50_10360	COG1819	glycosyl
EXW50_10365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW50_10370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW50_10395	COG0456	acetyltransferase
EXW50_10415	COG3874	Sporulation protein YtfJ
EXW50_10440	COG2226	methyltransferase
EXW50_10460	COG1082	Xylose isomerase domain protein TIM barrel
EXW50_10465	COG0346	lactoylglutathione lyase activity
EXW50_10475	COG0604	alcohol dehydrogenase
EXW50_10480	COG1595	DNA-templated transcription, initiation
EXW50_10505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW50_10505	COG0426	domain, Protein
EXW50_10515	COG0386	Belongs to the glutathione peroxidase family
EXW50_10520	COG1305	Transglutaminase-like
EXW50_10525	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW50_10530	COG0714	Associated with various cellular activities
EXW50_10535	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW50_10540	COG1140	nitrate reductase beta subunit
EXW50_10545	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW50_10550	COG2181	nitrate reductase activity
EXW50_10555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW50_10560	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW50_10565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW50_10570	COG0303	'Molybdopterin
EXW50_10575	COG0314	molybdopterin synthase activity
EXW50_10585	COG2223	nitrite transmembrane transporter activity
EXW50_10605	COG1648	precorrin-2 dehydrogenase activity
EXW50_10615	COG1587	Uroporphyrinogen-III synthase
EXW50_10615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW50_10620	COG2146	nitrite reductase [NAD(P)H] activity
EXW50_10625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW50_10630	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW50_10655	COG2359	stage V sporulation protein S
EXW50_10665	COG2856	Zn peptidase
EXW50_10750	COG0582	viral genome integration into host DNA
EXW50_10775	COG0582	viral genome integration into host DNA
EXW50_10795	COG5484	DNA packaging
EXW50_10800	COG1783	phage Terminase large subunit
EXW50_10815	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EXW50_10820	COG4653	Phage capsid family
EXW50_10950	COG1418	mRNA catabolic process
EXW50_10955	COG0488	(ABC) transporter
EXW50_10975	COG1413	lyase activity
EXW50_10990	COG2136	Putative SAM-dependent methyltransferase
EXW50_10990	COG2521	methyltransferase
EXW50_10995	COG0018	arginyl-trna synthetase
EXW50_11050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW50_11060	COG0017	Asparaginyl-tRNA synthetase
EXW50_11065	COG0733	neurotransmitter:sodium symporter activity
EXW50_11095	COG2610	gluconate transmembrane transporter activity
EXW50_11105	COG1794	racemase activity, acting on amino acids and derivatives
EXW50_11115	COG0456	acetyltransferase
EXW50_11120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW50_11125	COG1131	(ABC) transporter
EXW50_11130	COG4473	ABC transporter
EXW50_11140	COG0546	phosphoglycolate phosphatase activity
EXW50_11195	COG0768	penicillin binding
EXW50_11205	COG0204	Acyl-transferase
EXW50_11210	COG1272	protein, Hemolysin III
EXW50_11215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW50_11220	COG0805	protein transport
EXW50_11235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW50_11240	COG1999	signal sequence binding
EXW50_11245	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW50_11250	COG0367	asparagine synthase
EXW50_11265	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW50_11270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW50_11275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW50_11295	COG1335	isochorismatase
EXW50_11305	COG0668	transmembrane transport
EXW50_11310	COG2203	Gaf domain
EXW50_11310	COG4585	Histidine kinase
EXW50_11315	COG2197	response regulator
EXW50_11320	COG1737	Transcriptional regulator
EXW50_11325	COG1064	alcohol dehydrogenase
EXW50_11340	COG1070	Carbohydrate kinase
EXW50_11350	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW50_11370	COG0517	IMP dehydrogenase activity
EXW50_11370	COG1125	glycine betaine transport
EXW50_11375	COG1174	glycine betaine transport
EXW50_11410	COG1253	flavin adenine dinucleotide binding
EXW50_11415	COG1012	belongs to the aldehyde dehydrogenase family
EXW50_11420	COG5506	Protein of unknown function (DUF1694)
EXW50_11435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW50_11440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW50_11445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW50_11450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW50_11455	COG0456	acetyltransferase
EXW50_11460	COG3829	transcription factor binding
EXW50_11465	COG1509	lysine 2,3-aminomutase activity
EXW50_11475	COG4479	Belongs to the UPF0346 family
EXW50_11480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW50_11540	COG5293	efflux transmembrane transporter activity
EXW50_11570	COG0515	serine threonine protein kinase
EXW50_11570	COG3064	Membrane
EXW50_11570	COG4991	sh3 domain protein
EXW50_11580	COG0671	phosphoesterase, PA-phosphatase related
EXW50_11585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW50_11590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW50_11650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW50_11675	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_11695	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW50_11695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW50_11705	COG2814	Major facilitator Superfamily
EXW50_11715	COG0372	Belongs to the citrate synthase family
EXW50_11720	COG2079	MmgE PrpD family protein
EXW50_11725	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW50_11730	COG1960	acyl-CoA dehydrogenase activity
EXW50_11735	COG2084	Dehydrogenase
EXW50_11740	COG1012	belongs to the aldehyde dehydrogenase family
EXW50_11745	COG1280	lysine exporter protein (LysE YggA)
EXW50_11750	COG1024	Enoyl-CoA hydratase
EXW50_11765	COG0420	3'-5' exonuclease activity
EXW50_11785	COG2223	nitrite transmembrane transporter activity
EXW50_11790	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_11795	COG1169	isochorismate synthase
EXW50_11800	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW50_11805	COG3433	isochorismatase activity
EXW50_11805	COG1535	isochorismatase
EXW50_11810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW50_11815	COG3251	PFAM MbtH domain protein
EXW50_11820	COG2814	Major facilitator Superfamily
EXW50_11835	COG0776	regulation of translation
EXW50_11845	COG2318	DinB family
EXW50_11850	COG1115	amino acid carrier protein
EXW50_11865	COG2329	Antibiotic biosynthesis monooxygenase
EXW50_11880	COG1187	pseudouridine synthase activity
EXW50_11885	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW50_11890	COG3655	Transcriptional regulator
EXW50_11900	COG1136	(ABC) transporter
EXW50_11910	COG0596	Alpha beta hydrolase
EXW50_11925	COG0028	Belongs to the TPP enzyme family
EXW50_11950	COG1253	flavin adenine dinucleotide binding
EXW50_12000	COG1846	Transcriptional regulator
EXW50_12010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW50_12015	COG1309	transcriptional regulator
EXW50_12025	COG0697	spore germination
EXW50_12030	COG0531	amino acid
EXW50_12045	COG1247	-acetyltransferase
EXW50_12085	COG0596	Alpha beta hydrolase
EXW50_12090	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW50_12100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW50_12130	COG0583	DNA-binding transcription factor activity
EXW50_12135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW50_12150	COG0583	DNA-binding transcription factor activity
EXW50_12155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW50_12160	COG2258	MOSC domain
EXW50_12170	COG1132	(ABC) transporter
EXW50_12175	COG1132	(ABC) transporter
EXW50_12195	COG1396	sequence-specific DNA binding
EXW50_12230	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW50_12235	COG1595	DNA-templated transcription, initiation
EXW50_12255	COG1649	PFAM Uncharacterised BCR, COG1649
EXW50_12275	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW50_12280	COG2971	BadF BadG BcrA BcrD
EXW50_12350	COG0500	methyltransferase
EXW50_12350	COG3615	Tellurite resistance protein tehB
EXW50_12360	COG0693	protein deglycase activity
EXW50_12370	COG0588	phosphoglycerate mutase activity
EXW50_12390	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW50_12395	COG0110	maltose O-acetyltransferase activity
EXW50_12410	COG1136	(ABC) transporter
EXW50_12425	COG5002	protein histidine kinase activity
EXW50_12430	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_12440	COG1686	Belongs to the peptidase S11 family
EXW50_12465	COG0768	penicillin binding
EXW50_12470	COG0745	RESPONSE REGULATOR receiver
EXW50_12475	COG2205	protein histidine kinase activity
EXW50_12480	COG1136	(ABC) transporter
EXW50_12485	COG0577	efflux transmembrane transporter activity
EXW50_12495	COG1595	DNA-templated transcription, initiation
EXW50_12505	COG0768	penicillin binding
EXW50_12510	COG0768	penicillin binding
EXW50_12545	COG1252	NADH dehydrogenase
EXW50_12550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW50_12550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW50_12565	COG0697	spore germination
EXW50_12595	COG3397	chitin binding
EXW50_12600	COG0823	Involved in the tonB-independent uptake of proteins
EXW50_12610	COG1408	metallophosphoesterase
EXW50_12620	COG1131	(ABC) transporter
EXW50_12630	COG1309	transcriptional regulator
EXW50_12640	COG1960	acyl-CoA dehydrogenase activity
EXW50_12645	COG0439	Biotin carboxylase
EXW50_12650	COG0511	ligase activity, forming carbon-carbon bonds
EXW50_12655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW50_12660	COG1024	Enoyl-CoA hydratase
EXW50_12665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW50_12670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW50_12710	COG0572	uridine kinase
EXW50_12715	COG2318	DinB family
EXW50_12745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW50_12775	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW50_12800	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_12805	COG1733	regulation of RNA biosynthetic process
EXW50_12830	COG1309	transcriptional regulator
EXW50_12860	COG0697	spore germination
EXW50_12865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW50_12895	COG2323	membrane
EXW50_12910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW50_12915	COG0697	spore germination
EXW50_12935	COG0201	protein transport
EXW50_12945	COG0737	Belongs to the 5'-nucleotidase family
EXW50_12955	COG3227	Zinc metalloprotease (Elastase)
EXW50_12960	COG1523	belongs to the glycosyl hydrolase 13 family
EXW50_12975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW50_12980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW50_12985	COG1073	alpha beta
EXW50_12995	COG0577	efflux transmembrane transporter activity
EXW50_13000	COG1136	(ABC) transporter
EXW50_13030	COG5002	protein histidine kinase activity
EXW50_13035	COG0745	RESPONSE REGULATOR receiver
EXW50_13040	COG1011	Hydrolase
EXW50_13065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW50_13070	COG1183	phosphatidylcholine synthase activity
EXW50_13085	COG1132	(ABC) transporter
EXW50_13095	COG3961	Belongs to the TPP enzyme family
EXW50_13115	COG0322	excinuclease ABC activity
EXW50_13140	COG2318	DinB family
EXW50_13155	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW50_13180	COG3878	Protein conserved in bacteria
EXW50_13205	COG1051	belongs to the nudix hydrolase family
EXW50_13210	COG0592	DNA-directed DNA polymerase activity
EXW50_13215	COG2816	NAD+ diphosphatase activity
EXW50_13225	COG2223	nitrite transmembrane transporter activity
EXW50_13230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW50_13240	COG0494	nUDIX hydrolase
EXW50_13260	COG0697	spore germination
EXW50_13265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW50_13280	COG0584	glycerophosphoryl diester phosphodiesterase
EXW50_13295	COG1733	regulation of RNA biosynthetic process
EXW50_13305	COG2814	Major facilitator Superfamily
EXW50_13320	COG2375	cellular response to nickel ion
EXW50_13320	COG1132	(ABC) transporter
EXW50_13325	COG1132	(ABC) transporter
EXW50_13360	COG0768	penicillin binding
EXW50_13365	COG0671	phosphoesterase, PA-phosphatase related
EXW50_13370	COG0604	alcohol dehydrogenase
EXW50_13375	COG5002	protein histidine kinase activity
EXW50_13380	COG0745	RESPONSE REGULATOR receiver
EXW50_13390	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW50_13400	COG2205	protein histidine kinase activity
EXW50_13415	COG1122	ATPase activity
EXW50_13420	COG4720	Psort location CytoplasmicMembrane, score
EXW50_13425	COG1794	racemase activity, acting on amino acids and derivatives
EXW50_13430	COG1819	glycosyl
EXW50_13440	COG0768	penicillin binding
EXW50_13445	COG5002	protein histidine kinase activity
EXW50_13480	COG0561	phosphatase activity
EXW50_13530	COG2124	cytochrome p450
EXW50_13580	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW50_13590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW50_13595	COG0460	homoserine dehydrogenase
EXW50_13615	COG0577	efflux transmembrane transporter activity
EXW50_13620	COG1136	(ABC) transporter
EXW50_13630	COG0488	(ABC) transporter
EXW50_13635	COG0667	Aldo Keto reductase
EXW50_13640	COG0583	DNA-binding transcription factor activity
EXW50_13645	COG2205	protein histidine kinase activity
EXW50_13650	COG0745	RESPONSE REGULATOR receiver
EXW50_13660	COG3773	Cell wall hydrolase
EXW50_13665	COG0604	alcohol dehydrogenase
EXW50_13695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW50_13710	COG2959	enzyme of heme biosynthesis
EXW50_13740	COG3483	tryptophan 2,3-dioxygenase activity
EXW50_13745	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW50_13750	COG3844	kynureninase activity
EXW50_13755	COG1309	transcriptional regulator
EXW50_13785	COG1349	DNA-binding transcription factor activity
EXW50_13815	COG2223	nitrite transmembrane transporter activity
EXW50_13825	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_13830	COG0456	acetyltransferase
EXW50_13830	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW50_13865	COG4176	ABC-type proline glycine betaine transport system permease component
EXW50_13870	COG0517	IMP dehydrogenase activity
EXW50_13870	COG4175	Glycine betaine
EXW50_13895	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW50_13900	COG2153	protein acetylation
EXW50_13905	COG3397	chitin binding
EXW50_13915	COG1819	glycosyl
EXW50_13930	COG2205	protein histidine kinase activity
EXW50_13935	COG2315	Protein conserved in bacteria
EXW50_13980	COG3973	AAA domain
EXW50_13995	COG2105	PFAM AIG2 family protein
EXW50_14000	COG0514	ATP-dependent DNA helicase (RecQ)
EXW50_14020	COG4637	Psort location Cytoplasmic, score
EXW50_14040	COG1227	inorganic diphosphatase activity
EXW50_14045	COG3397	chitin binding
EXW50_14050	COG2318	DinB family
EXW50_14070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW50_14075	COG1115	amino acid carrier protein
EXW50_14080	COG1012	belongs to the aldehyde dehydrogenase family
EXW50_14085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW50_14095	COG3938	Belongs to the proline racemase family
EXW50_14100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW50_14150	COG0586	Pfam SNARE associated Golgi protein
EXW50_14165	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW50_14170	COG4166	transmembrane transport
EXW50_14180	COG4948	Mandelate Racemase Muconate Lactonizing
EXW50_14200	COG0667	Aldo Keto reductase
EXW50_14245	COG2936	dipeptidyl-peptidase activity
EXW50_14250	COG5002	protein histidine kinase activity
EXW50_14255	COG0745	RESPONSE REGULATOR receiver
EXW50_14285	COG1164	Oligoendopeptidase f
EXW50_14305	COG1307	EDD domain protein, DegV family
EXW50_14335	COG1335	isochorismatase
EXW50_14350	COG2814	Major facilitator Superfamily
EXW50_14360	COG1664	Polymer-forming cytoskeletal
EXW50_14365	COG0789	Transcriptional regulator
EXW50_14370	COG4533	DNA binding
EXW50_14375	COG2814	Major facilitator Superfamily
EXW50_14375	COG0477	Major facilitator Superfamily
EXW50_14390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW50_14395	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW50_14400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW50_14405	COG0438	transferase activity, transferring glycosyl groups
EXW50_14420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW50_14425	COG0438	transferase activity, transferring glycosyl groups
EXW50_14430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW50_14445	COG2261	transglycosylase associated protein
EXW50_14460	COG2226	methyltransferase
EXW50_14495	COG0436	Aminotransferase
EXW50_14500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW50_14525	COG1131	(ABC) transporter
EXW50_14530	COG2188	Transcriptional regulator
EXW50_14575	COG0628	permease
EXW50_14605	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW50_14615	COG0697	spore germination
EXW50_14620	COG2318	DinB family
EXW50_14650	COG0346	lactoylglutathione lyase activity
EXW50_14655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW50_14685	COG2814	Major facilitator Superfamily
EXW50_14690	COG1368	sulfuric ester hydrolase activity
EXW50_14705	COG0488	(ABC) transporter
EXW50_14710	COG1033	growth of symbiont in host cell
EXW50_14710	COG2409	Drug exporters of the RND superfamily
EXW50_14715	COG1309	transcriptional regulator
EXW50_14735	COG0287	Prephenate dehydrogenase
EXW50_14750	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW50_14750	COG1605	Chorismate mutase
EXW50_14800	COG1388	LysM domain
EXW50_14800	COG3584	3D domain protein
EXW50_14810	COG0346	lactoylglutathione lyase activity
EXW50_14845	COG0579	oxidoreductase
EXW50_14875	COG1830	Aldolase
EXW50_14880	COG2226	methyltransferase
EXW50_14895	COG0346	lactoylglutathione lyase activity
EXW50_14900	COG2329	Antibiotic biosynthesis monooxygenase
EXW50_14920	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW50_14925	COG2207	Transcriptional regulator
EXW50_14930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW50_14935	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW50_14940	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW50_14945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW50_14950	COG3239	Fatty acid desaturase
EXW50_14970	COG3655	Transcriptional regulator
EXW50_14985	COG4377	Putative membrane peptidase family (DUF2324)
EXW50_14995	COG3279	Response regulator of the LytR AlgR family
EXW50_15010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW50_15015	COG0346	lactoylglutathione lyase activity
EXW50_15050	COG0714	Associated with various cellular activities
EXW50_15070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW50_15075	COG0753	catalase activity
EXW50_15085	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW50_15105	COG0778	Nitroreductase
EXW50_15110	COG1846	Transcriptional regulator
EXW50_15130	COG0494	nUDIX hydrolase
EXW50_15150	COG1725	Transcriptional regulator
EXW50_15180	COG2207	Transcriptional regulator
EXW50_15185	COG0456	acetyltransferase
EXW50_15200	COG0697	spore germination
EXW50_15205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW50_15210	COG1671	Belongs to the UPF0178 family
EXW50_15230	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW50_15230	COG0456	acetyltransferase
EXW50_15255	COG0730	response to heat
EXW50_15265	COG0833	amino acid
EXW50_15275	COG4335	DNA alkylation repair
EXW50_15310	COG0768	penicillin binding
EXW50_15320	COG3104	oligopeptide transport
EXW50_15325	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW50_15340	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW50_15345	COG1984	allophanate hydrolase subunit 2
EXW50_15350	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW50_15355	COG1414	Transcriptional regulator
EXW50_15375	COG1960	acyl-CoA dehydrogenase activity
EXW50_15400	COG0640	Transcriptional regulator
EXW50_15420	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW50_15435	COG0574	Belongs to the PEP-utilizing enzyme family
EXW50_15435	COG3848	Pyruvate phosphate dikinase
EXW50_15460	COG1136	(ABC) transporter
EXW50_15495	COG1073	alpha beta
EXW50_15540	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW50_15560	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW50_15565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW50_15570	COG1121	(ABC) transporter
EXW50_15585	COG1999	signal sequence binding
EXW50_15590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW50_15595	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW50_15620	COG0798	PFAM Bile acid sodium symporter
EXW50_15625	COG0346	lactoylglutathione lyase activity
EXW50_15630	COG0640	Transcriptional regulator
EXW50_15685	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_15690	COG1522	sequence-specific DNA binding
EXW50_15705	COG0346	lactoylglutathione lyase activity
EXW50_15725	COG2226	methyltransferase
EXW50_15735	COG2814	Major facilitator Superfamily
EXW50_15760	COG0745	RESPONSE REGULATOR receiver
EXW50_15765	COG5002	protein histidine kinase activity
EXW50_15765	COG3850	Histidine kinase
EXW50_15795	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW50_15835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW50_15845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW50_15865	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW50_15885	COG1136	(ABC) transporter
EXW50_15890	COG0577	efflux transmembrane transporter activity
EXW50_15910	COG5002	protein histidine kinase activity
EXW50_15910	COG3850	Histidine kinase
EXW50_15925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW50_15945	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW50_15965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW50_16030	COG2814	Major facilitator Superfamily
EXW50_16050	COG1876	peptidase activity
EXW50_16055	COG2843	Capsule synthesis protein
EXW50_16070	COG0477	Major facilitator Superfamily
EXW50_16085	COG1846	Transcriptional regulator
EXW50_16090	COG2814	Major facilitator Superfamily
EXW50_16105	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EXW50_16115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW50_16125	COG0789	Transcriptional regulator
EXW50_16160	COG1476	TRANSCRIPTIONal
EXW50_16175	COG1288	antiporter activity
EXW50_16180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW50_16225	COG3718	enzyme involved in inositol metabolism
EXW50_16230	COG0191	fructose-bisphosphate aldolase activity
EXW50_16255	COG0673	inositol 2-dehydrogenase activity
EXW50_16260	COG2814	Major facilitator Superfamily
EXW50_16265	COG1609	Transcriptional regulator
EXW50_16270	COG2003	Belongs to the UPF0758 family
EXW50_16325	COG0494	nUDIX hydrolase
EXW50_16355	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW50_16385	COG0739	heme binding
EXW50_16435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW50_16490	COG4187	Peptidase family M20/M25/M40
EXW50_16505	COG2031	fatty acid transporter
EXW50_16515	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW50_16560	COG1122	ATPase activity
EXW50_16580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW50_16585	COG1288	antiporter activity
EXW50_16590	COG2356	endonuclease I
EXW50_16595	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW50_16620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW50_16640	COG1785	Belongs to the alkaline phosphatase family
EXW50_16645	COG0778	Nitroreductase
EXW50_16650	COG1733	regulation of RNA biosynthetic process
EXW50_16670	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_16680	COG1131	(ABC) transporter
EXW50_16700	COG0494	nUDIX hydrolase
EXW50_16715	COG1011	Hydrolase
EXW50_16720	COG2365	Tyrosine phosphatase family
EXW50_16745	COG0346	lactoylglutathione lyase activity
EXW50_16750	COG1940	carbohydrate kinase activity
EXW50_16755	COG0738	Major facilitator superfamily
EXW50_16760	COG0110	maltose O-acetyltransferase activity
EXW50_16775	COG0628	permease
EXW50_16780	COG2261	transglycosylase associated protein
EXW50_16815	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW50_16825	COG1253	flavin adenine dinucleotide binding
EXW50_16830	COG0789	Transcriptional regulator
EXW50_16835	COG0697	spore germination
EXW50_16840	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW50_16845	COG3813	Protein conserved in bacteria
EXW50_16850	COG2706	6-phosphogluconolactonase activity
EXW50_16855	COG1070	Carbohydrate kinase
EXW50_16865	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW50_16870	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW50_16885	COG0814	amino acid
EXW50_16905	COG1393	Belongs to the ArsC family
EXW50_16915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW50_16930	COG0494	nUDIX hydrolase
EXW50_16955	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_16965	COG0318	PFAM AMP-dependent synthetase and ligase
EXW50_16970	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW50_16975	COG1733	regulation of RNA biosynthetic process
EXW50_16990	COG1191	sigma factor activity
EXW50_17020	COG1876	peptidase activity
EXW50_17040	COG0741	lytic transglycosylase activity
EXW50_17060	COG5002	protein histidine kinase activity
EXW50_17065	COG0745	RESPONSE REGULATOR receiver
EXW50_17085	COG0657	acetylesterase activity
EXW50_17095	COG2814	Major facilitator Superfamily
EXW50_17100	COG1309	transcriptional regulator
EXW50_17110	COG3226	Transcriptional regulator
EXW50_17115	COG1280	lysine exporter protein (LysE YggA)
EXW50_17145	COG0814	amino acid
EXW50_17170	COG1151	hydroxylamine reductase activity
EXW50_17215	COG2072	flavoprotein involved in K transport
EXW50_17260	COG1695	Transcriptional regulator
EXW50_17265	COG0604	alcohol dehydrogenase
EXW50_17270	COG1113	amino acid transport
EXW50_17280	COG2814	Major facilitator Superfamily
EXW50_17310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW50_17315	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW50_17335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW50_17340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW50_17345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW50_17350	COG3739	integral membrane protein
EXW50_17375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW50_17380	COG0583	DNA-binding transcription factor activity
EXW50_17405	COG1193	negative regulation of DNA recombination
EXW50_17425	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW50_17430	COG1164	Oligoendopeptidase f
EXW50_17435	COG2957	Belongs to the agmatine deiminase family
EXW50_17455	COG3781	membrane
EXW50_17470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW50_17505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW50_17510	COG0640	Transcriptional regulator
EXW50_17515	COG0604	alcohol dehydrogenase
EXW50_17520	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW50_17530	COG0457	Tetratricopeptide repeat
EXW50_17535	COG2808	Putative FMN-binding domain
EXW50_17545	COG0277	FAD linked oxidase domain protein
EXW50_17565	COG1285	pathogenesis
EXW50_17580	COG2514	catechol 2,3-dioxygenase activity
EXW50_17585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW50_17590	COG1126	abc transporter atp-binding protein
EXW50_17595	COG0765	amino acid transport
EXW50_17600	COG2720	vancomycin resistance protein
EXW50_17630	COG1278	Cold shock
EXW50_17640	COG0716	FMN binding
EXW50_17650	COG0494	nUDIX hydrolase
EXW50_17670	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_17680	COG0165	Argininosuccinate lyase
EXW50_17695	COG4145	pantothenate transmembrane transporter activity
EXW50_17705	COG1012	belongs to the aldehyde dehydrogenase family
EXW50_17710	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_17720	COG1657	PFAM Prenyltransferase squalene oxidase
EXW50_17725	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW50_17730	COG2962	Rard protein
EXW50_17735	COG3326	Membrane
EXW50_17740	COG0531	amino acid
EXW50_17770	COG2226	methyltransferase
EXW50_17775	COG4166	transmembrane transport
EXW50_17780	COG4166	transmembrane transport
EXW50_17785	COG4166	transmembrane transport
EXW50_17795	COG1131	(ABC) transporter
EXW50_17815	COG0673	inositol 2-dehydrogenase activity
EXW50_17820	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW50_17825	COG0187	DNA topoisomerase II activity
EXW50_17830	COG1832	CoA-binding protein
EXW50_17835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW50_17840	COG0745	RESPONSE REGULATOR receiver
EXW50_17850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW50_17850	COG1328	CTP reductase activity
EXW50_17860	COG4841	protein insertion into membrane
EXW50_17865	COG0824	Thioesterase
EXW50_17890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW50_17905	COG1266	CAAX protease self-immunity
EXW50_17910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW50_17940	COG2211	Major facilitator Superfamily
EXW50_17950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW50_17965	COG0183	Belongs to the thiolase family
EXW50_17970	COG0318	PFAM AMP-dependent synthetase and ligase
EXW50_17975	COG1268	BioY protein
EXW50_17980	COG0318	PFAM AMP-dependent synthetase and ligase
EXW50_17985	COG1396	sequence-specific DNA binding
EXW50_18025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW50_18040	COG5002	protein histidine kinase activity
EXW50_18050	COG0400	carboxylic ester hydrolase activity
EXW50_18055	COG0346	lactoylglutathione lyase activity
EXW50_18065	COG0069	glutamate synthase activity
EXW50_18070	COG1902	pentaerythritol trinitrate reductase activity
EXW50_18075	COG1329	Transcriptional regulator
EXW50_18080	COG0010	Belongs to the arginase family
EXW50_18090	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW50_18095	COG2986	histidine ammonia-lyase
EXW50_18105	COG2226	methyltransferase
EXW50_18135	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW50_18140	COG0785	Cytochrome C biogenesis protein
EXW50_18155	COG1473	amidohydrolase
EXW50_18160	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW50_18165	COG1131	(ABC) transporter
EXW50_18175	COG0583	DNA-binding transcription factor activity
EXW50_18185	COG1346	cytolysis
EXW50_18200	COG0730	response to heat
EXW50_18210	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW50_18210	COG3409	Peptidoglycan-binding domain 1 protein
EXW50_18230	COG1132	(ABC) transporter
EXW50_18235	COG1132	(ABC) transporter
EXW50_18255	COG4886	Leucine-rich repeat (LRR) protein
EXW50_18255	COG4932	domain protein
EXW50_18325	COG3763	UPF0154 protein
EXW50_18345	COG3639	organic phosphonate transmembrane transporter activity
EXW50_18355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW50_18360	COG0737	Belongs to the 5'-nucleotidase family
EXW50_18370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW50_18375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW50_18390	COG1695	Transcriptional regulator
EXW50_18395	COG1132	(ABC) transporter
EXW50_18430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW50_18440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW50_18445	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW50_18445	COG3420	alginic acid biosynthetic process
EXW50_18475	COG1216	Glycosyl transferase, family 2
EXW50_18495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW50_18495	COG0463	Glycosyl transferase, family 2
EXW50_18500	COG0438	transferase activity, transferring glycosyl groups
EXW50_18505	COG0438	transferase activity, transferring glycosyl groups
EXW50_18510	COG1086	Polysaccharide biosynthesis protein
EXW50_18515	COG0489	protein tyrosine kinase activity
EXW50_18520	COG3944	biosynthesis protein
EXW50_18525	COG0174	glutamine synthetase
EXW50_18530	COG0789	Transcriptional regulator
EXW50_18535	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW50_18540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW50_18545	COG2860	membrane
EXW50_18550	COG0464	growth
EXW50_18570	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW50_18580	COG1388	LysM domain
EXW50_18580	COG3584	3D domain protein
EXW50_18585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW50_18585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW50_18585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW50_18590	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW50_18595	COG1349	DNA-binding transcription factor activity
EXW50_18600	COG1979	alcohol dehydrogenase
EXW50_18605	COG2322	membrane
EXW50_18615	COG1113	amino acid transport
EXW50_18630	COG1473	amidohydrolase
EXW50_18635	COG1408	metallophosphoesterase
EXW50_18640	COG2116	formate transmembrane transporter activity
EXW50_18655	COG2217	Heavy metal translocating P-type atpase
EXW50_18660	COG2608	mercury ion transmembrane transporter activity
EXW50_18665	COG1937	Protein conserved in bacteria
EXW50_18695	COG4566	intracellular signal transduction
EXW50_18700	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW50_18705	COG2819	hydrolase of the alpha beta superfamily
EXW50_18710	COG1120	ATPase activity
EXW50_18715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW50_18720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW50_18725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW50_18730	COG0708	Exodeoxyribonuclease III
EXW50_18735	COG2169	Transcriptional regulator
EXW50_18740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW50_18745	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW50_18755	COG2706	6-phosphogluconolactonase activity
EXW50_18760	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW50_18765	COG2364	Membrane
EXW50_18785	COG0346	lactoylglutathione lyase activity
EXW50_18790	COG3300	MHYT domain
EXW50_18790	COG5001	Diguanylate cyclase
EXW50_18830	COG1346	cytolysis
EXW50_18840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW50_18845	COG2945	thiolester hydrolase activity
EXW50_18845	COG0596	Alpha beta hydrolase
EXW50_18850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW50_18860	COG2188	Transcriptional regulator
EXW50_18865	COG2723	6-phospho-beta-galactosidase activity
EXW50_18870	COG0840	transmembrane signaling receptor activity
EXW50_18880	COG3773	Cell wall hydrolase
EXW50_18895	COG1368	sulfuric ester hydrolase activity
EXW50_18900	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW50_18915	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW50_18925	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW50_18930	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW50_18940	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW50_18945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW50_18950	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW50_18955	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW50_18955	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW50_18965	COG2359	stage V sporulation protein S
EXW50_18970	COG1692	metallophosphoesterase
EXW50_18975	COG1418	mRNA catabolic process
EXW50_18980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW50_18985	COG1058	Belongs to the CinA family
EXW50_18985	COG1546	Belongs to the CinA family
EXW50_18990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW50_18995	COG1426	Protein conserved in bacteria
EXW50_19010	COG0300	oxidoreductase activity
EXW50_19015	COG0612	Peptidase, M16
EXW50_19020	COG0612	Peptidase, M16
EXW50_19025	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW50_19030	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW50_19035	COG3845	ABC transporter
EXW50_19040	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW50_19045	COG2188	Transcriptional regulator
EXW50_19050	COG1674	ftsk spoiiie
EXW50_19060	COG0740	serine-type endopeptidase activity
EXW50_19065	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW50_19075	COG0527	aspartate kinase activity
EXW50_19080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW50_19085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW50_19090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW50_19095	COG1873	PFAM PRC-barrel domain
EXW50_19100	COG0612	Peptidase, M16
EXW50_19105	COG0726	polysaccharide deacetylase
EXW50_19110	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW50_19120	COG0196	riboflavin kinase activity
EXW50_19130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW50_19135	COG1550	Protein conserved in bacteria
EXW50_19140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW50_19145	COG1358	cellular component organization or biogenesis
EXW50_19150	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW50_19155	COG0195	Participates in both transcription termination and antitermination
EXW50_19160	COG0779	Required for maturation of 30S ribosomal subunits
EXW50_19170	COG0442	prolyl-tRNA aminoacylation
EXW50_19175	COG0750	zinc metalloprotease
EXW50_19185	COG4589	Belongs to the CDS family
EXW50_19195	COG0233	cytoplasmic translational termination
EXW50_19200	COG0528	UMP kinase activity
EXW50_19205	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW50_19210	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW50_19215	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW50_19220	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW50_19225	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW50_19230	COG4974	Belongs to the 'phage' integrase family
EXW50_19235	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW50_19240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW50_19245	COG0758	DNA mediated transformation
EXW50_19250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW50_19255	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW50_19260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW50_19275	COG0335	large ribosomal subunit rRNA binding
EXW50_19280	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW50_19285	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW50_19290	COG1837	Belongs to the UPF0109 family
EXW50_19300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW50_19305	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EXW50_19310	COG0552	protein localization to endoplasmic reticulum
EXW50_19315	COG1196	nuclear chromosome segregation
EXW50_19320	COG0571	ribonuclease III activity
EXW50_19325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW50_19330	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_19335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW50_19340	COG0416	fatty acid biosynthetic process
EXW50_19345	COG1349	DNA-binding transcription factor activity
EXW50_19345	COG2050	protein possibly involved in aromatic compounds catabolism
EXW50_19350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW50_19355	COG1461	Dihydroxyacetone kinase
EXW50_19360	COG1302	Protein conserved in bacteria
EXW50_19375	COG1564	THIamine pyrophosphokinase
EXW50_19380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW50_19390	COG2815	serine threonine protein kinase
EXW50_19390	COG0515	serine threonine protein kinase
EXW50_19395	COG0631	protein serine/threonine phosphatase activity
EXW50_19400	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW50_19405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW50_19405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW50_19410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW50_19415	COG0242	peptide deformylase activity
EXW50_19420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW50_19425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW50_19430	COG1758	RNA polymerase activity
EXW50_19445	COG1561	YicC-like family, N-terminal region
EXW50_19450	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW50_19465	COG0006	proline dipeptidase activity
EXW50_19525	COG0167	dihydroorotate dehydrogenase activity
EXW50_19530	COG0543	2 iron, 2 sulfur cluster binding
EXW50_19535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW50_19545	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW50_19550	COG0540	Belongs to the ATCase OTCase family
EXW50_19560	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW50_19565	COG0564	pseudouridine synthase activity
EXW50_19570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW50_19580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW50_19585	COG3599	regulation of cell shape
EXW50_19590	COG2302	S4 RNA-binding domain
EXW50_19595	COG0762	integral membrane protein
EXW50_19600	COG1799	cell septum assembly
EXW50_19605	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW50_19615	COG1873	PFAM PRC-barrel domain
EXW50_19620	COG1191	sigma factor activity
EXW50_19625	COG1191	sigma factor activity
EXW50_19635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW50_19640	COG0849	cell division
EXW50_19645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW50_19660	COG0772	Belongs to the SEDS family
EXW50_19665	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW50_19670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW50_19675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW50_19680	COG0768	penicillin binding
EXW50_19685	COG0768	penicillin binding
EXW50_19695	COG0275	rRNA processing
EXW50_19700	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW50_19705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW50_19710	COG0454	-acetyltransferase
EXW50_19720	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW50_19725	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW50_19730	COG1323	Belongs to the UPF0348 family
EXW50_19735	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW50_19740	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW50_19745	COG3314	Sporulation integral membrane protein YlbJ
EXW50_19750	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EXW50_19755	COG0742	ribosomal rna small subunit methyltransferase
EXW50_19765	COG4471	UPF0298 protein
EXW50_19770	COG3679	Belongs to the UPF0342 family
EXW50_19775	COG0406	alpha-ribazole phosphatase activity
EXW50_19790	COG2340	Cysteine-rich secretory protein family
EXW50_19800	COG3336	cytochrome c oxidase
EXW50_19825	COG0109	protoheme IX farnesyltransferase activity
EXW50_19830	COG1612	heme a metabolic process
EXW50_19835	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW50_19845	COG0772	Belongs to the SEDS family
EXW50_19850	COG4838	Belongs to the UPF0358 family
EXW50_19855	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW50_19860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW50_19870	COG4896	Protein conserved in bacteria
EXW50_19885	COG1217	gtp-binding protein TYPA
EXW50_19895	COG0483	inositol monophosphate 1-phosphatase activity
EXW50_19905	COG4493	Belongs to the UPF0637 family
EXW50_19910	COG4476	Belongs to the UPF0223 family
EXW50_19920	COG1982	Orn Lys Arg decarboxylase major
EXW50_19965	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW50_19970	COG0022	dehydrogenase e1 component
EXW50_19975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW50_19990	COG0561	phosphatase activity
EXW50_20000	COG5503	Protein of unknown function (DUF1447)
EXW50_20005	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW50_20010	COG0569	domain protein
EXW50_20020	COG1473	amidohydrolase
EXW50_20025	COG2171	N-acyltransferase activity
EXW50_20030	COG0583	DNA-binding transcription factor activity
EXW50_20035	COG0517	IMP dehydrogenase activity
EXW50_20045	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW50_20055	COG4703	Protein of unknown function (DUF1797)
EXW50_20070	COG2200	EAL domain
EXW50_20075	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_20080	COG1408	metallophosphoesterase
EXW50_20125	COG2814	Major facilitator Superfamily
EXW50_20135	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW50_20145	COG3209	COG3209 Rhs family protein
EXW50_20155	COG2205	protein histidine kinase activity
EXW50_20165	COG0436	Aminotransferase
EXW50_20170	COG1609	Transcriptional regulator
EXW50_20175	COG3833	ABC-type maltose transport systems, permease component
EXW50_20180	COG1175	transmembrane transport
EXW50_20185	COG2182	Extracellular solute-binding protein
EXW50_20195	COG0366	Alpha amylase catalytic
EXW50_20200	COG3842	ATPase activity
EXW50_20245	COG0183	Belongs to the thiolase family
EXW50_20280	COG1695	Transcriptional regulator
EXW50_20285	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_20295	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW50_20300	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW50_20305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW50_20310	COG0436	Aminotransferase
EXW50_20315	COG1850	ribulose-bisphosphate carboxylase activity
EXW50_20320	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW50_20325	COG0235	Class ii aldolase
EXW50_20330	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW50_20345	COG2084	Dehydrogenase
EXW50_20355	COG2199	diguanylate cyclase activity
EXW50_20360	COG0778	Nitroreductase
EXW50_20385	COG1263	PTS System
EXW50_20385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW50_20385	COG2190	(PTS) system
EXW50_20390	COG3711	transcriptional antiterminator
EXW50_20400	COG2188	Transcriptional regulator
EXW50_20405	COG0363	glucosamine-6-phosphate deaminase activity
EXW50_20410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW50_20420	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW50_20430	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW50_20440	COG1547	Domain of unknown function (DUF309)
EXW50_20450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW50_20455	COG4086	secreted protein
EXW50_20460	COG0561	phosphatase activity
EXW50_20465	COG0697	spore germination
EXW50_20480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW50_20505	COG0733	neurotransmitter:sodium symporter activity
EXW50_20525	COG1686	Belongs to the peptidase S11 family
EXW50_20530	COG1725	Transcriptional regulator
EXW50_20535	COG1131	(ABC) transporter
EXW50_20555	COG1846	Transcriptional regulator
EXW50_20570	COG0598	Magnesium transport protein CorA
EXW50_20585	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW50_20595	COG4974	Belongs to the 'phage' integrase family
EXW50_20605	COG0735	belongs to the Fur family
EXW50_20610	COG1300	Membrane
EXW50_20630	COG0667	Aldo Keto reductase
EXW50_20635	COG0656	L-ascorbic acid biosynthetic process
EXW50_20640	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW50_20640	COG0456	acetyltransferase
EXW50_20650	COG4085	toxin activity
EXW50_20650	COG1525	nuclease
EXW50_20650	COG0737	Belongs to the 5'-nucleotidase family
EXW50_20655	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW50_20665	COG0596	Alpha beta hydrolase
EXW50_20670	COG2056	Na+-H+ antiporter family
EXW50_20675	COG1609	Transcriptional regulator
EXW50_20680	COG0456	acetyltransferase
EXW50_20685	COG1073	alpha beta
EXW50_20700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW50_20700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW50_20705	COG0307	riboflavin synthase, alpha
EXW50_20710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW50_20710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW50_20725	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW50_20730	COG4106	trans-aconitate 2-methyltransferase activity
EXW50_20735	COG2226	methyltransferase
EXW50_20735	COG1073	alpha beta
EXW50_20740	COG0156	8-amino-7-oxononanoate synthase activity
EXW50_20750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW50_20760	COG1757	Na H antiporter
EXW50_20765	COG0737	Belongs to the 5'-nucleotidase family
EXW50_20775	COG1522	sequence-specific DNA binding
EXW50_20800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW50_20810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW50_20825	COG0300	oxidoreductase activity
EXW50_20830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW50_20835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW50_20840	COG1760	l-serine dehydratase
EXW50_20845	COG1760	l-serine dehydratase
EXW50_20855	COG1234	tRNA 3'-trailer cleavage
EXW50_20890	COG1131	(ABC) transporter
EXW50_20915	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW50_20920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW50_20930	COG1376	ErfK ybiS ycfS ynhG family protein
EXW50_20935	COG4129	membrane
EXW50_20940	COG1126	abc transporter atp-binding protein
EXW50_20945	COG0765	amino acid transport
EXW50_20950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW50_20965	COG2323	membrane
EXW50_20970	COG0772	Belongs to the SEDS family
EXW50_20980	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW50_20985	COG0022	dehydrogenase e1 component
EXW50_20990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW50_20995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW50_21000	COG3426	butyrate kinase activity
EXW50_21010	COG0280	phosphate acetyltransferase
EXW50_21020	COG3290	protein histidine kinase activity
EXW50_21020	COG3829	transcription factor binding
EXW50_21030	COG0584	glycerophosphoryl diester phosphodiesterase
EXW50_21035	COG3093	addiction module antidote protein HigA
EXW50_21045	COG0745	RESPONSE REGULATOR receiver
EXW50_21055	COG0750	zinc metalloprotease
EXW50_21060	COG0497	DNA recombination
EXW50_21065	COG1438	arginine binding
EXW50_21070	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW50_21075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW50_21080	COG0142	geranyltranstransferase activity
EXW50_21085	COG1722	exodeoxyribonuclease VII activity
EXW50_21090	COG1570	exodeoxyribonuclease VII activity
EXW50_21095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW50_21100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW50_21105	COG1302	Protein conserved in bacteria
EXW50_21110	COG0439	Biotin carboxylase
EXW50_21115	COG0511	ligase activity, forming carbon-carbon bonds
EXW50_21160	COG3854	ATPases associated with a variety of cellular activities
EXW50_21180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW50_21185	COG0006	proline dipeptidase activity
EXW50_21190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW50_21200	COG3872	metal-dependent enzyme
EXW50_21210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW50_21215	COG1321	iron dependent repressor
EXW50_21245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW50_21255	COG1609	Transcriptional regulator
EXW50_21265	COG2076	Multidrug Resistance protein
EXW50_21270	COG2076	Multidrug Resistance protein
EXW50_21305	COG1725	Transcriptional regulator
EXW50_21320	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW50_21325	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW50_21330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW50_21335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW50_21365	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW50_21390	COG4970	Tfp pilus assembly protein FimT
EXW50_21400	COG1459	type II secretion system
EXW50_21405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW50_21460	COG1410	methionine synthase
EXW50_21460	COG0646	methionine synthase
EXW50_21465	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW50_21465	COG0646	methionine synthase
EXW50_21470	COG0626	cystathionine gamma-synthase activity
EXW50_21475	COG0626	cystathionine gamma-synthase activity
EXW50_21490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW50_21500	COG1940	carbohydrate kinase activity
EXW50_21505	COG4483	Protein conserved in bacteria
EXW50_21510	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW50_21515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW50_21520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW50_21525	COG0704	Plays a role in the regulation of phosphate uptake
EXW50_21540	COG0581	inorganic phosphate transmembrane transporter activity
EXW50_21545	COG0573	inorganic phosphate transmembrane transporter activity
EXW50_21550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW50_21555	COG0768	penicillin binding
EXW50_21560	COG0477	Major facilitator Superfamily
EXW50_21565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW50_21585	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW50_21590	COG0735	belongs to the Fur family
EXW50_21595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW50_21600	COG1121	(ABC) transporter
EXW50_21605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW50_21615	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW50_21630	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW50_21635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW50_21640	COG2384	SAM-dependent methyltransferase
EXW50_21650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW50_21655	COG0358	DNA primase activity
EXW50_21665	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW50_21670	COG0517	IMP dehydrogenase activity
EXW50_21675	COG1381	Involved in DNA repair and RecF pathway recombination
EXW50_21685	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW50_21690	COG0295	cytidine deaminase activity
EXW50_21695	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW50_21700	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW50_21705	COG1480	7TM receptor with intracellular HD hydrolase
EXW50_21710	COG1702	phosphate starvation-inducible protein PhoH
EXW50_21725	COG1610	YqeY-like protein
EXW50_21730	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW50_21735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW50_21740	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW50_21750	COG0484	heat shock protein binding
EXW50_21755	COG0443	Heat shock 70 kDa protein
EXW50_21765	COG1420	regulation of RNA biosynthetic process
EXW50_21770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW50_21775	COG1733	regulation of RNA biosynthetic process
EXW50_21780	COG0481	GTPase activity
EXW50_21790	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW50_21795	COG0268	Binds directly to 16S ribosomal RNA
EXW50_21800	COG1466	dna polymerase III delta subunit
EXW50_21810	COG0658	competence protein
EXW50_21810	COG2333	competence protein COMEC
EXW50_21815	COG2131	deaminase
EXW50_21820	COG1555	photosystem II stabilization
EXW50_21820	COG1596	polysaccharide export
EXW50_21825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW50_21830	COG2226	methyltransferase
EXW50_21835	COG0799	negative regulation of ribosome biogenesis
EXW50_21840	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW50_21845	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW50_21850	COG1534	Rna-binding protein
EXW50_21855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW50_21860	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW50_21865	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW50_21875	COG0688	phosphatidylethanolamine metabolic process
EXW50_21885	COG1595	DNA-templated transcription, initiation
EXW50_21890	COG2357	RelA SpoT domain protein
EXW50_21900	COG1785	Belongs to the alkaline phosphatase family
EXW50_21910	COG2267	carboxylic ester hydrolase activity
EXW50_21945	COG1404	Belongs to the peptidase S8 family
EXW50_21950	COG3186	Phenylalanine-4-hydroxylase
EXW50_21955	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW50_21960	COG2514	catechol 2,3-dioxygenase activity
EXW50_21965	COG2259	Doxx family
EXW50_22005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW50_22015	COG1012	belongs to the aldehyde dehydrogenase family
EXW50_22015	COG1454	alcohol dehydrogenase
EXW50_22020	COG0626	cystathionine gamma-synthase activity
EXW50_22025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW50_22030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW50_22035	COG2226	methyltransferase
EXW50_22050	COG0768	penicillin binding
EXW50_22055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW50_22060	COG0572	uridine kinase
EXW50_22065	COG0826	peptidase U32
EXW50_22070	COG0826	peptidase U32
EXW50_22075	COG4122	O-methyltransferase activity
EXW50_22080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW50_22090	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW50_22095	COG4472	Bacterial protein of unknown function (DUF965)
EXW50_22100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW50_22110	COG0628	permease
EXW50_22130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW50_22140	COG0482	sulfurtransferase activity
EXW50_22145	COG1104	cysteine desulfurase activity
EXW50_22150	COG1959	2 iron, 2 sulfur cluster binding
EXW50_22155	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW50_22170	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW50_22175	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW50_22185	COG1490	D-aminoacyl-tRNA deacylase activity
EXW50_22190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW50_22195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW50_22200	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW50_22200	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW50_22205	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW50_22210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW50_22210	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW50_22220	COG2244	polysaccharide biosynthetic process
EXW50_22225	COG2323	membrane
EXW50_22235	COG1862	Preprotein translocase
EXW50_22240	COG0343	queuine tRNA-ribosyltransferase activity
EXW50_22245	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW50_22255	COG2255	four-way junction helicase activity
EXW50_22260	COG0632	four-way junction helicase activity
EXW50_22265	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW50_22290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW50_22295	COG0157	Belongs to the NadC ModD family
EXW50_22300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW50_22305	COG1104	cysteine desulfurase activity
EXW50_22310	COG1827	regulation of RNA biosynthetic process
EXW50_22315	COG2258	MOSC domain
EXW50_22320	COG0077	Prephenate dehydratase
EXW50_22325	COG0577	efflux transmembrane transporter activity
EXW50_22330	COG0577	efflux transmembrane transporter activity
EXW50_22335	COG1136	(ABC) transporter
EXW50_22340	COG5002	protein histidine kinase activity
EXW50_22345	COG0745	RESPONSE REGULATOR receiver
EXW50_22350	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW50_22355	COG3290	protein histidine kinase activity
EXW50_22365	COG2868	ribosomal protein
EXW50_22375	COG1530	ribonuclease E activity
EXW50_22380	COG1994	Peptidase M50
EXW50_22385	COG0739	heme binding
EXW50_22390	COG2894	cell division
EXW50_22395	COG0850	regulation of cytokinetic process
EXW50_22410	COG1077	Cell shape determining protein MreB Mrl
EXW50_22415	COG2003	Belongs to the UPF0758 family
EXW50_22420	COG0424	maF-like protein
EXW50_22435	COG0285	dihydrofolate synthase activity
EXW50_22450	COG1388	LysM domain
EXW50_22455	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW50_22460	COG0113	porphobilinogen synthase activity
EXW50_22465	COG1587	Uroporphyrinogen-III synthase
EXW50_22470	COG0181	hydroxymethylbilane synthase activity
EXW50_22475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW50_22480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW50_22485	COG1846	Transcriptional regulator
EXW50_22490	COG1764	response to oxidative stress
EXW50_22495	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW50_22505	COG1067	ATP-dependent peptidase activity
EXW50_22505	COG0470	DNA polymerase III
EXW50_22515	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW50_22545	COG0622	Phosphoesterase
EXW50_22555	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW50_22560	COG5401	PFAM Sporulation and spore germination
EXW50_22570	COG0477	Major facilitator Superfamily
EXW50_22580	COG1309	transcriptional regulator
EXW50_22590	COG2197	response regulator
EXW50_22595	COG2233	PERMEase
EXW50_22600	COG0402	S-adenosylhomocysteine deaminase activity
EXW50_22605	COG1983	PspC domain protein
EXW50_22610	COG1396	sequence-specific DNA binding
EXW50_22615	COG0697	spore germination
EXW50_22625	COG1959	2 iron, 2 sulfur cluster binding
EXW50_22630	COG1668	transmembrane transport
EXW50_22635	COG4152	abc transporter atp-binding protein
EXW50_22640	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW50_22645	COG1360	Flagellar Motor Protein
EXW50_22650	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW50_22660	COG1876	peptidase activity
EXW50_22665	COG0824	Thioesterase
EXW50_22670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW50_22675	COG1053	succinate dehydrogenase
EXW50_22680	COG2009	succinate dehydrogenase
EXW50_22685	COG1719	4-vinyl reductase, 4VR
EXW50_22690	COG0322	excinuclease ABC activity
EXW50_22695	COG3118	belongs to the thioredoxin family
EXW50_22700	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW50_22705	COG2086	electron transfer activity
EXW50_22710	COG1024	Enoyl-CoA hydratase
EXW50_22715	COG1309	transcriptional regulator
EXW50_22720	COG0318	PFAM AMP-dependent synthetase and ligase
EXW50_22745	COG2318	DinB family
EXW50_22770	COG1131	(ABC) transporter
EXW50_22775	COG2205	protein histidine kinase activity
EXW50_22780	COG0745	RESPONSE REGULATOR receiver
EXW50_22785	COG4895	conserved protein (DUF2196)
EXW50_22790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW50_22795	COG2329	Antibiotic biosynthesis monooxygenase
EXW50_22800	COG4509	Sortase family
EXW50_22805	COG1120	ATPase activity
EXW50_22820	COG5386	Cell surface protein
EXW50_22830	COG5386	Cell surface protein
EXW50_22835	COG1114	Component of the transport system for branched-chain amino acids
EXW50_22845	COG1193	negative regulation of DNA recombination
EXW50_22850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW50_22850	COG1796	DNA polymerase
EXW50_22855	COG1286	toxin biosynthetic process
EXW50_22860	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW50_22865	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW50_22890	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW50_22895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW50_22910	COG1418	mRNA catabolic process
EXW50_22940	COG2814	Major facilitator Superfamily
EXW50_22945	COG1566	PFAM secretion protein HlyD family protein
EXW50_22950	COG1309	transcriptional regulator
EXW50_22955	COG1363	Peptidase, m42
EXW50_22965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW50_22980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW50_22990	COG1484	DNA-dependent DNA replication
EXW50_22995	COG3611	Membrane attachment protein
EXW50_23000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW50_23005	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW50_23010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW50_23015	COG0237	dephospho-CoA kinase activity
EXW50_23020	COG1971	Probably functions as a manganese efflux pump
EXW50_23030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW50_23030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW50_23035	COG5002	protein histidine kinase activity
EXW50_23040	COG0745	RESPONSE REGULATOR receiver
EXW50_23055	COG0039	L-malate dehydrogenase activity
EXW50_23060	COG0538	isocitrate dehydrogenase activity
EXW50_23065	COG0372	Belongs to the citrate synthase family
EXW50_23090	COG0628	permease
EXW50_23095	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW50_23105	COG0205	6-phosphofructokinase activity
EXW50_23115	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW50_23120	COG1725	Transcriptional regulator
EXW50_23125	COG0281	malic enzyme
EXW50_23130	COG0587	DNA-directed DNA polymerase activity
EXW50_23145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW50_23165	COG4109	DRTGG domain
EXW50_23170	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW50_23175	COG0006	proline dipeptidase activity
EXW50_23220	COG0662	Cupin 2, conserved barrel domain protein
EXW50_23230	COG1476	TRANSCRIPTIONal
EXW50_23245	COG1028	Short-chain dehydrogenase reductase Sdr
EXW50_23250	COG0589	response to stress
EXW50_23270	COG0165	Argininosuccinate lyase
EXW50_23275	COG0137	argininosuccinate synthase activity
EXW50_23290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW50_23305	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW50_23310	COG0827	DNA restriction-modification system
EXW50_23315	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW50_23320	COG3874	Sporulation protein YtfJ
EXW50_23335	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW50_23345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW50_23360	COG1104	cysteine desulfurase activity
EXW50_23365	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW50_23380	COG1309	transcriptional regulator
EXW50_23385	COG1956	GAF domain-containing protein
EXW50_23390	COG0626	cystathionine gamma-synthase activity
EXW50_23395	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW50_23420	COG1595	DNA-templated transcription, initiation
EXW50_23430	COG0110	maltose O-acetyltransferase activity
EXW50_23435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW50_23440	COG0454	-acetyltransferase
EXW50_23445	COG0517	IMP dehydrogenase activity
EXW50_23450	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW50_23465	COG0745	RESPONSE REGULATOR receiver
EXW50_23470	COG5002	protein histidine kinase activity
EXW50_23475	COG0666	response to abiotic stimulus
EXW50_23485	COG1970	mechanosensitive ion channel activity
EXW50_23510	COG1609	Transcriptional regulator
EXW50_23515	COG1605	Chorismate mutase
EXW50_23515	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW50_23520	COG1605	Chorismate mutase
EXW50_23520	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW50_23525	COG4851	CamS sex pheromone cAM373 precursor
EXW50_23530	COG3118	belongs to the thioredoxin family
EXW50_23540	COG2309	aminopeptidase activity
EXW50_23565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW50_23570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW50_23580	COG1674	ftsk spoiiie
EXW50_23595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW50_23600	COG4848	Belongs to the UPF0354 family
EXW50_23605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW50_23610	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW50_23615	COG1363	Peptidase, m42
EXW50_23625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW50_23630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW50_23640	COG0510	thiamine kinase activity
EXW50_23645	COG1523	belongs to the glycosyl hydrolase 13 family
EXW50_23655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW50_23660	COG1349	DNA-binding transcription factor activity
EXW50_23665	COG1187	pseudouridine synthase activity
EXW50_23670	COG2244	polysaccharide biosynthetic process
EXW50_23675	COG2081	HI0933 family
EXW50_23680	COG2814	Major facilitator Superfamily
EXW50_23690	COG3832	glyoxalase III activity
EXW50_23710	COG1329	Transcriptional regulator
EXW50_23735	COG0314	molybdopterin synthase activity
EXW50_23740	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW50_23745	COG0303	'Molybdopterin
EXW50_23750	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW50_23755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW50_23760	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW50_23785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW50_23795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW50_23835	COG0495	leucyl-tRNA aminoacylation
EXW50_23840	COG2814	Major facilitator Superfamily
EXW50_23845	COG0475	glutathione-regulated potassium exporter activity
EXW50_23850	COG0490	domain, Protein
EXW50_23855	COG0582	viral genome integration into host DNA
EXW50_23870	COG1136	(ABC) transporter
EXW50_23890	COG1242	4 iron, 4 sulfur cluster binding
EXW50_23895	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW50_23905	COG1794	racemase activity, acting on amino acids and derivatives
EXW50_23920	COG2267	carboxylic ester hydrolase activity
EXW50_23925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW50_23930	COG0671	phosphoesterase, PA-phosphatase related
EXW50_23935	COG0438	transferase activity, transferring glycosyl groups
EXW50_23960	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW50_23965	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW50_23990	COG5002	protein histidine kinase activity
EXW50_23995	COG3852	Histidine kinase
EXW50_24000	COG0753	catalase activity
EXW50_24005	COG2267	carboxylic ester hydrolase activity
EXW50_24010	COG1368	sulfuric ester hydrolase activity
EXW50_24015	COG4895	conserved protein (DUF2196)
EXW50_24030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW50_24035	COG1116	anion transmembrane transporter activity
EXW50_24040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW50_24065	COG0494	nUDIX hydrolase
EXW50_24110	COG2076	Multidrug Resistance protein
EXW50_24115	COG2076	Multidrug Resistance protein
EXW50_24120	COG0789	Transcriptional regulator
EXW50_24125	COG1854	S-ribosylhomocysteine lyase activity
EXW50_24135	COG0288	reversible hydration of carbon dioxide
EXW50_24140	COG1271	oxidase subunit
EXW50_24145	COG1294	oxidase, subunit
EXW50_24165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW50_24190	COG1842	Phage shock protein A
EXW50_24220	COG5002	protein histidine kinase activity
EXW50_24225	COG0745	RESPONSE REGULATOR receiver
EXW50_24250	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW50_24255	COG1597	lipid kinase activity
EXW50_24270	COG1136	(ABC) transporter
EXW50_24300	COG5002	protein histidine kinase activity
EXW50_24310	COG0586	Pfam SNARE associated Golgi protein
EXW50_24325	COG0577	efflux transmembrane transporter activity
EXW50_24330	COG1136	(ABC) transporter
EXW50_24335	COG3708	Transcriptional regulator
EXW50_24335	COG2207	Transcriptional regulator
EXW50_24345	COG1131	(ABC) transporter
EXW50_24350	COG5658	integral membrane protein
EXW50_24355	COG0640	Transcriptional regulator
EXW50_24360	COG0745	RESPONSE REGULATOR receiver
EXW50_24365	COG2205	protein histidine kinase activity
EXW50_24370	COG0577	efflux transmembrane transporter activity
EXW50_24375	COG0577	efflux transmembrane transporter activity
EXW50_24380	COG1136	(ABC) transporter
EXW50_24385	COG0577	efflux transmembrane transporter activity
EXW50_24400	COG2188	Transcriptional regulator
EXW50_24420	COG3964	amidohydrolase
EXW50_24440	COG4948	Mandelate Racemase Muconate Lactonizing
EXW50_24445	COG0318	PFAM AMP-dependent synthetase and ligase
EXW50_24450	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW50_24455	COG0596	Alpha beta hydrolase
EXW50_24460	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW50_24465	COG1169	isochorismate synthase
EXW50_24470	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW50_24475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW50_24480	COG1278	Cold shock
EXW50_24500	COG0058	SHG alpha-glucan phosphorylase activity
EXW50_24510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW50_24515	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW50_24520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW50_24535	COG1309	transcriptional regulator
EXW50_24670	COG1285	pathogenesis
EXW50_24675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW50_24685	COG0166	Belongs to the GPI family
EXW50_24695	COG2155	Conserved Protein
EXW50_24700	COG1098	S1 RNA binding domain
EXW50_24705	COG0436	Aminotransferase
EXW50_24710	COG1522	sequence-specific DNA binding
EXW50_24715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW50_24720	COG2267	carboxylic ester hydrolase activity
EXW50_24730	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW50_24745	COG5018	Exonuclease
EXW50_24750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW50_24770	COG2050	protein possibly involved in aromatic compounds catabolism
EXW50_24780	COG1268	BioY protein
EXW50_24785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW50_24790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW50_24800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW50_24805	COG3584	3D domain protein
EXW50_24820	COG1252	NADH dehydrogenase
EXW50_24825	COG0492	ferredoxin-NADP+ reductase activity
EXW50_24845	COG1683	Conserved Protein
EXW50_24870	COG0316	Belongs to the HesB IscA family
EXW50_24875	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW50_24880	COG4844	belongs to the
EXW50_24885	COG1252	NADH dehydrogenase
EXW50_24895	COG0390	transport system, permease component
EXW50_24900	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW50_24935	COG4837	Protein of unknown function (DUF1462)
EXW50_24940	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW50_24950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW50_24955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW50_24980	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW50_24990	COG0647	UMP catabolic process
EXW50_25000	COG2445	Protein of unknown function DUF86
EXW50_25005	COG1494	fructose-1,6-bisphosphatase
EXW50_25020	COG4470	Protein conserved in bacteria
EXW50_25030	COG0789	Transcriptional regulator
EXW50_25035	COG4377	Putative membrane peptidase family (DUF2324)
EXW50_25055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW50_25060	COG0739	heme binding
EXW50_25070	COG3377	Domain of unknown function (DUF1805)
EXW50_25075	COG0737	Belongs to the 5'-nucleotidase family
EXW50_25080	COG1695	Transcriptional regulator
EXW50_25090	COG0719	Fe-S assembly protein
EXW50_25095	COG0822	iron-sulfur transferase activity
EXW50_25100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW50_25105	COG0719	Fe-S assembly protein
EXW50_25110	COG0396	ATPase activity
EXW50_25115	COG1464	Belongs to the NlpA lipoprotein family
EXW50_25120	COG1464	Belongs to the NlpA lipoprotein family
EXW50_25125	COG2011	ABC-type metal ion transport system permease component
EXW50_25130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW50_25140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW50_25145	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW50_25150	COG0509	glycine decarboxylation via glycine cleavage system
EXW50_25155	COG1393	Belongs to the ArsC family
EXW50_25200	COG1309	transcriptional regulator
EXW50_25205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW50_25210	COG1960	acyl-CoA dehydrogenase activity
EXW50_25215	COG0183	Belongs to the thiolase family
EXW50_25220	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW50_25220	COG1024	Enoyl-CoA hydratase
EXW50_25230	COG1686	Belongs to the peptidase S11 family
EXW50_25235	COG0506	proline dehydrogenase activity
EXW50_25245	COG0011	TIGRFAM Protein of
EXW50_25250	COG0840	transmembrane signaling receptor activity
EXW50_25265	COG2814	Major facilitator Superfamily
EXW50_25270	COG0531	amino acid
EXW50_25295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW50_25325	COG0586	Pfam SNARE associated Golgi protein
EXW50_25335	COG1376	ErfK ybiS ycfS ynhG family protein
EXW50_25340	COG0745	RESPONSE REGULATOR receiver
EXW50_25345	COG5002	protein histidine kinase activity
EXW50_25355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW50_25365	COG0840	transmembrane signaling receptor activity
EXW50_25370	COG0840	transmembrane signaling receptor activity
EXW50_25375	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW50_25380	COG3227	Zinc metalloprotease (Elastase)
EXW50_25385	COG1741	Belongs to the pirin family
EXW50_25400	COG0586	Pfam SNARE associated Golgi protein
EXW50_25405	COG0475	glutathione-regulated potassium exporter activity
EXW50_25410	COG0490	domain, Protein
EXW50_25415	COG1115	amino acid carrier protein
EXW50_25425	COG0783	Belongs to the Dps family
EXW50_25435	COG2318	DinB family
EXW50_25445	COG1611	Belongs to the LOG family
EXW50_25455	COG1528	Iron-storage protein
EXW50_25460	COG2311	Membrane
EXW50_25465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW50_25470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW50_25475	COG1115	amino acid carrier protein
EXW50_25480	COG1115	amino acid carrier protein
EXW50_25485	COG2910	NAD(P)H-binding
EXW50_25505	COG0656	L-ascorbic acid biosynthetic process
EXW50_25510	COG2814	Major facilitator Superfamily
EXW50_25515	COG1733	regulation of RNA biosynthetic process
EXW50_25525	COG1252	NADH dehydrogenase
EXW50_25545	COG3290	protein histidine kinase activity
EXW50_25545	COG0840	transmembrane signaling receptor activity
EXW50_25560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW50_25580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW50_25595	COG4224	UPF0291 protein
EXW50_25600	COG1335	isochorismatase
EXW50_25605	COG1522	sequence-specific DNA binding
EXW50_25615	COG1522	sequence-specific DNA binding
EXW50_25620	COG0288	reversible hydration of carbon dioxide
EXW50_25625	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW50_25630	COG2233	PERMEase
EXW50_25670	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW50_25680	COG0557	exoribonuclease II activity
EXW50_25685	COG1647	Serine aminopeptidase, S33
EXW50_25690	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW50_25695	COG1346	cytolysis
EXW50_25710	COG0148	phosphopyruvate hydratase activity
EXW50_25720	COG0149	triose-phosphate isomerase activity
EXW50_25725	COG0126	phosphoglycerate kinase activity
EXW50_25730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW50_25745	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW50_25775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW50_25790	COG2323	membrane
EXW50_25805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW50_25810	COG1481	regulation of sporulation
EXW50_25815	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW50_25820	COG1660	Displays ATPase and GTPase activities
EXW50_25825	COG1051	belongs to the nudix hydrolase family
EXW50_25835	COG0492	ferredoxin-NADP+ reductase activity
EXW50_25840	COG0457	Tetratricopeptide repeat
EXW50_25845	COG0110	maltose O-acetyltransferase activity
EXW50_25850	COG0546	phosphoglycolate phosphatase activity
EXW50_25855	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW50_25860	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW50_25865	COG1950	PFAM Membrane protein of
EXW50_25870	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW50_25890	COG0789	Transcriptional regulator
EXW50_25925	COG0583	DNA-binding transcription factor activity
EXW50_25930	COG0789	Transcriptional regulator
EXW50_25935	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW50_25940	COG0488	(ABC) transporter
EXW50_25950	COG1132	(ABC) transporter
EXW50_25955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW50_25960	COG0793	Belongs to the peptidase S41A family
EXW50_25960	COG3409	Peptidoglycan-binding domain 1 protein
EXW50_25965	COG2177	Part of the ABC transporter FtsEX involved in
EXW50_25970	COG2884	Cell division ATP-binding protein ftsE
EXW50_26005	COG1131	(ABC) transporter
EXW50_26040	COG1278	Cold shock
EXW50_26045	COG1040	competence protein
EXW50_26050	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW50_26055	COG1388	LysM domain
EXW50_26055	COG0791	NLP P60 protein
EXW50_26060	COG1733	regulation of RNA biosynthetic process
EXW50_26065	COG1307	EDD domain protein, DegV family
EXW50_26070	COG1739	Uncharacterized protein family UPF0029
EXW50_26075	COG1316	TRANSCRIPTIONal
EXW50_26080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW50_26085	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW50_26090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW50_26100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW50_26100	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW50_26120	COG1486	melibiose metabolic process
EXW50_26125	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW50_26130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW50_26140	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW50_26150	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW50_26160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW50_26165	COG1301	dicarboxylic acid transport
EXW50_26180	COG1511	domain protein
EXW50_26185	COG0583	DNA-binding transcription factor activity
EXW50_26190	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW50_26195	COG1271	oxidase subunit
EXW50_26200	COG1294	oxidase, subunit
EXW50_26205	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW50_26210	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW50_26215	COG1620	l-lactate permease
EXW50_26225	COG2389	metal-binding protein
EXW50_26240	COG1368	sulfuric ester hydrolase activity
EXW50_26250	COG1388	LysM domain
EXW50_26250	COG0791	NLP P60 protein
EXW50_26255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW50_26265	COG1215	transferase activity, transferring glycosyl groups
EXW50_26270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW50_26280	COG1388	LysM domain
EXW50_26280	COG3584	3D domain protein
EXW50_26305	COG4715	Zinc finger, swim domain protein
EXW50_26310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW50_26355	COG0577	efflux transmembrane transporter activity
EXW50_26360	COG1136	(ABC) transporter
EXW50_26380	COG2271	Major facilitator Superfamily
EXW50_26395	COG5002	protein histidine kinase activity
EXW50_26395	COG3850	Histidine kinase
EXW50_26400	COG0745	RESPONSE REGULATOR receiver
EXW50_26405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW50_26420	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW50_26435	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW50_26460	COG1316	TRANSCRIPTIONal
EXW50_26470	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EXW50_26480	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EXW50_26485	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW50_26505	COG0438	transferase activity, transferring glycosyl groups
EXW50_26515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW50_26525	COG1086	Polysaccharide biosynthesis protein
EXW50_26535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW50_26540	COG1086	Polysaccharide biosynthesis protein
EXW50_26545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW50_26550	COG4464	protein tyrosine phosphatase activity
EXW50_26555	COG0489	protein tyrosine kinase activity
EXW50_26560	COG3944	biosynthesis protein
EXW50_26565	COG0489	protein tyrosine kinase activity
EXW50_26580	COG1609	Transcriptional regulator
EXW50_26595	COG0739	heme binding
EXW50_26610	COG3279	Response regulator of the LytR AlgR family
EXW50_26615	COG2385	sporulation resulting in formation of a cellular spore
EXW50_26630	COG4836	Membrane
EXW50_26635	COG1007	ATP synthesis coupled electron transport
EXW50_26640	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW50_26645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW50_26650	COG0713	ATP synthesis coupled electron transport
EXW50_26655	COG0839	Belongs to the complex I subunit 6 family
EXW50_26665	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW50_26670	COG0649	NAD binding
EXW50_26675	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW50_26680	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW50_26685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW50_26690	COG3300	MHYT domain
EXW50_26690	COG5001	Diguanylate cyclase
EXW50_26705	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW50_26710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW50_26715	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW50_26720	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW50_26725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW50_26730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW50_26740	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW50_26765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW50_26775	COG0698	ribose 5-phosphate isomerase
EXW50_26785	COG2190	(PTS) system
EXW50_26790	COG2259	Doxx family
EXW50_26795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW50_26805	COG1971	Probably functions as a manganese efflux pump
EXW50_26810	COG0009	L-threonylcarbamoyladenylate synthase
EXW50_26825	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW50_26830	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW50_26840	COG1435	thymidine kinase activity
EXW50_26850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW50_26855	COG1494	fructose-1,6-bisphosphatase
EXW50_26875	COG4821	SIS domain
EXW50_26880	COG0504	CTP synthase activity
EXW50_26885	COG3343	RNA polymerase activity
EXW50_26895	COG1960	acyl-CoA dehydrogenase activity
EXW50_26900	COG1960	acyl-CoA dehydrogenase activity
EXW50_26905	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW50_26910	COG0183	Belongs to the thiolase family
EXW50_26915	COG0247	lactate metabolic process
EXW50_26915	COG2181	nitrate reductase activity
EXW50_26920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW50_26925	COG4294	response to UV
EXW50_26930	COG5001	Diguanylate cyclase
EXW50_26930	COG3300	MHYT domain
EXW50_26955	COG2197	response regulator
EXW50_26960	COG4585	Histidine kinase
EXW50_26965	COG0842	Transport permease protein
EXW50_26970	COG1131	(ABC) transporter
EXW50_26975	COG0024	Methionine aminopeptidase
EXW50_26985	COG2234	aminopeptidase activity
EXW50_27000	COG4506	Protein conserved in bacteria
EXW50_27005	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW50_27025	COG0010	Belongs to the arginase family
EXW50_27030	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW50_27035	COG2814	Major facilitator Superfamily
EXW50_27040	COG0789	Transcriptional regulator
EXW50_27045	COG0584	glycerophosphoryl diester phosphodiesterase
EXW50_27050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW50_27060	COG1994	Peptidase M50
EXW50_27070	COG1078	dGTPase activity
EXW50_27075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW50_27080	COG1120	ATPase activity
EXW50_27085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW50_27090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW50_27095	COG4844	belongs to the
EXW50_27115	COG0280	phosphate acetyltransferase
EXW50_27120	COG3253	May function as heme-dependent peroxidase
EXW50_27130	COG3773	Cell wall hydrolase
EXW50_27140	COG2363	Small membrane protein
EXW50_27155	COG2233	PERMEase
EXW50_27160	COG0561	phosphatase activity
EXW50_27165	COG2814	Major facilitator Superfamily
EXW50_27170	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW50_27175	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW50_27180	COG1131	(ABC) transporter
EXW50_27185	COG2755	lipolytic protein G-D-S-L family
EXW50_27190	COG1609	Transcriptional regulator
EXW50_27200	COG0460	homoserine dehydrogenase
EXW50_27205	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW50_27210	COG2873	o-acetylhomoserine
EXW50_27225	COG2197	response regulator
EXW50_27230	COG4585	Histidine kinase
EXW50_27230	COG2203	Gaf domain
EXW50_27235	COG0351	phosphomethylpyrimidine kinase
EXW50_27240	COG3706	GGDEF domain
EXW50_27245	COG2879	small protein
EXW50_27250	COG1966	Carbon starvation protein
EXW50_27255	COG3279	Response regulator of the LytR AlgR family
EXW50_27260	COG0477	Major facilitator Superfamily
EXW50_27290	COG0840	transmembrane signaling receptor activity
EXW50_27300	COG1607	acyl-coa hydrolase
EXW50_27310	COG1216	Glycosyl transferase, family 2
EXW50_27315	COG0488	(ABC) transporter
EXW50_27330	COG0463	Glycosyl transferase, family 2
EXW50_27335	COG1309	transcriptional regulator
EXW50_27340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW50_27345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW50_27345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW50_27350	COG0628	permease
EXW50_27360	COG1380	Effector of murein hydrolase LrgA
EXW50_27365	COG3279	Response regulator of the LytR AlgR family
EXW50_27370	COG3275	phosphorelay sensor kinase activity
EXW50_27375	COG2814	Major facilitator Superfamily
EXW50_27380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW50_27385	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW50_27395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW50_27445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW50_27450	COG1272	protein, Hemolysin III
EXW50_27480	COG1164	Oligoendopeptidase f
EXW50_27490	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW50_27500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW50_27505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW50_27510	COG4853	Protein conserved in bacteria
EXW50_27520	COG5002	protein histidine kinase activity
EXW50_27525	COG0745	RESPONSE REGULATOR receiver
EXW50_27555	COG0305	Participates in initiation and elongation during chromosome replication
EXW50_27560	COG0359	binds to the 23S rRNA
EXW50_27565	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW50_27570	COG4241	membrane
EXW50_27580	COG0629	single-stranded DNA binding
EXW50_27585	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW50_27590	COG0012	GTP binding
EXW50_27595	COG4481	Protein conserved in bacteria
EXW50_27600	COG0668	transmembrane transport
EXW50_27610	COG1475	DNA binding
EXW50_27615	COG1192	Involved in chromosome partitioning
EXW50_27620	COG1475	DNA binding
EXW50_27625	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW50_27630	COG0445	tRNA wobble uridine modification
EXW50_27635	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW50_27640	COG1847	R3H domain protein
EXW50_27645	COG0706	membrane insertase activity
EXW50_27650	COG0594	ribonuclease P activity
EXW50_27655	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW50_27675	COG5002	protein histidine kinase activity
EXW50_27710	COG0778	Nitroreductase
EXW50_27735	COG0384	phenazine biosynthesis protein PhzF
EXW50_27740	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EXW50_27760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW50_27775	COG1674	ftsk spoiiie
EXW50_27900	COG0367	asparagine synthase
EXW50_28075	COG1396	sequence-specific DNA binding
EXW50_28140	COG0463	Glycosyl transferase, family 2
EXW50_28145	COG0463	Glycosyl transferase, family 2
EXW50_28150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW50_28155	COG1086	Polysaccharide biosynthesis protein
EXW50_28160	COG1088	dTDP-glucose 4,6-dehydratase activity
EXW50_28165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW50_28170	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW50_28185	COG2089	acid synthase
EXW50_28190	COG4641	Protein conserved in bacteria
EXW50_28230	COG2720	vancomycin resistance protein
EXW50_28265	COG2755	lipolytic protein G-D-S-L family
EXW50_28265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW50_28285	COG0756	dUTP diphosphatase activity
EXW50_28330	COG2002	toxin-antitoxin pair type II binding
EXW50_28340	COG1923	regulation of RNA biosynthetic process
EXW50_28375	COG2814	Major facilitator Superfamily
EXW50_28400	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW50_28410	COG2002	toxin-antitoxin pair type II binding
EXW50_28445	COG0582	viral genome integration into host DNA
EXW50_28480	COG1696	Membrane protein involved in D-alanine export
EXW50_28490	COG2814	Major facilitator Superfamily
EXW50_28510	COG3344	reverse transcriptase
EXW50_28550	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW50_28575	COG3103	Sh3 type 3 domain protein
EXW50_28575	COG0791	NLP P60 protein
EXW50_28575	COG1388	LysM domain
EXW50_28595	COG4974	Belongs to the 'phage' integrase family
EXW50_28640	COG0083	homoserine kinase activity
EXW50_28680	COG0840	transmembrane signaling receptor activity
EXW50_28700	COG2267	carboxylic ester hydrolase activity
EXW50_28710	COG1285	pathogenesis
EXW50_28715	COG0833	amino acid
EXW50_28745	COG0745	RESPONSE REGULATOR receiver
EXW50_28770	COG3344	reverse transcriptase
EXW50_28795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW50_28805	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EXW50_28810	COG5002	protein histidine kinase activity
EXW50_28815	COG0745	RESPONSE REGULATOR receiver
EXW50_28820	COG4990	cell redox homeostasis
EXW50_28830	COG0768	penicillin binding
EXW50_28835	COG0583	DNA-binding transcription factor activity
EXW50_28850	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW50_28870	COG2333	competence protein COMEC
EXW50_28870	COG0658	competence protein
EXW50_28925	COG2423	ornithine cyclodeaminase activity
EXW50_28935	COG2175	clavaminate synthase activity
EXW50_28940	COG0137	argininosuccinate synthase activity
EXW50_28955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW50_28960	COG0251	oxidation-reduction process
EXW50_28970	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW50_28975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW50_28980	COG1960	acyl-CoA dehydrogenase activity
EXW50_29005	COG0556	nucleotide-excision repair
EXW50_29010	COG0039	L-malate dehydrogenase activity
EXW50_29030	COG0436	Aminotransferase
EXW50_29070	COG0492	ferredoxin-NADP+ reductase activity
EXW50_29085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW50_29085	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EXW50_29095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW50_29100	COG1960	acyl-CoA dehydrogenase activity
EXW50_29115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW50_29125	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EXW50_29155	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW50_29165	COG0438	transferase activity, transferring glycosyl groups
EXW50_29170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW50_29175	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW50_29190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW50_29200	COG1131	(ABC) transporter
EXW50_29215	COG2378	regulation of single-species biofilm formation
EXW50_29255	COG2002	toxin-antitoxin pair type II binding
EXW50_29325	COG2814	Major facilitator Superfamily
EXW50_29330	COG0583	DNA-binding transcription factor activity
EXW50_29410	COG2357	RelA SpoT domain protein
EXW50_29415	COG2814	Major facilitator Superfamily
EXW50_29425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW50_29535	COG3344	reverse transcriptase
EXW50_29585	COG1725	Transcriptional regulator
EXW50_29590	COG1131	(ABC) transporter
EXW50_29630	COG1329	Transcriptional regulator
EXW50_29645	COG1923	regulation of RNA biosynthetic process
EXW50_29665	COG0582	viral genome integration into host DNA
EXW50_29690	COG1695	Transcriptional regulator
EXW50_29770	COG0791	NLP P60 protein
EXW50_29770	COG3883	PFAM NLP P60 protein
EXW50_29850	COG1396	sequence-specific DNA binding
EXW50_29885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW50_29890	COG4974	Belongs to the 'phage' integrase family
EXW50_29895	COG0024	Methionine aminopeptidase