locus-tag	class	description
EXW62_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW62_00010	COG0592	DNA-directed DNA polymerase activity
EXW62_00015	COG2501	S4 domain
EXW62_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW62_00025	COG0187	DNA topoisomerase II activity
EXW62_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW62_00065	COG0516	GMP reductase activity
EXW62_00065	COG0517	IMP dehydrogenase activity
EXW62_00070	COG1686	Belongs to the peptidase S11 family
EXW62_00100	COG1428	Deoxynucleoside kinase
EXW62_00105	COG1428	Deoxynucleoside kinase
EXW62_00110	COG1335	isochorismatase
EXW62_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW62_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW62_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW62_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW62_00180	COG1982	Orn Lys Arg decarboxylase major
EXW62_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW62_00190	COG0470	DNA polymerase III
EXW62_00195	COG1774	PSP1 C-terminal conserved region
EXW62_00200	COG4467	Involved in initiation control of chromosome replication
EXW62_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW62_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW62_00220	COG2002	toxin-antitoxin pair type II binding
EXW62_00230	COG0084	hydrolase, TatD family'
EXW62_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW62_00250	COG4466	Protein conserved in bacteria
EXW62_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW62_00270	COG0251	oxidation-reduction process
EXW62_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW62_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW62_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW62_00305	COG2002	toxin-antitoxin pair type II binding
EXW62_00310	COG2244	polysaccharide biosynthetic process
EXW62_00315	COG3956	TIGRFAM MazG family protein
EXW62_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW62_00340	COG1098	S1 RNA binding domain
EXW62_00355	COG2208	phosphoserine phosphatase activity
EXW62_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW62_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW62_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW62_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW62_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW62_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW62_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW62_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW62_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW62_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW62_00420	COG1396	sequence-specific DNA binding
EXW62_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW62_00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW62_00515	COG3880	PFAM UvrB UvrC protein
EXW62_00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW62_00525	COG0542	response to heat
EXW62_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW62_00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW62_00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW62_00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW62_00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW62_00560	COG1045	serine acetyltransferase
EXW62_00565	COG0215	cysteine-tRNA ligase activity
EXW62_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW62_00580	COG3688	RNA-binding protein containing a PIN domain
EXW62_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW62_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW62_00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW62_00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW62_00610	COG0081	regulation of translation
EXW62_00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW62_00620	COG0222	ribosome binding
EXW62_00625	COG2813	Specifically methylates the guanine in position
EXW62_00630	COG0085	RNA polymerase activity
EXW62_00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW62_00640	COG1358	cellular component organization or biogenesis
EXW62_00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW62_00650	COG0049	tRNA binding
EXW62_00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW62_00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW62_00665	COG0051	transcription antitermination factor activity, RNA binding
EXW62_00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW62_00675	COG0088	Forms part of the polypeptide exit tunnel
EXW62_00680	COG0089	rRNA binding
EXW62_00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW62_00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW62_00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW62_00705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EXW62_00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW62_00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW62_00720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EXW62_00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW62_00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW62_00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW62_00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW62_00760	COG1841	ribosomal large subunit assembly
EXW62_00765	COG0200	Binds to the 23S rRNA
EXW62_00770	COG0201	protein transport
EXW62_00775	COG0563	adenylate kinase activity
EXW62_00780	COG0024	Methionine aminopeptidase
EXW62_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW62_00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW62_00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW62_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW62_00835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW62_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW62_00855	COG0489	protein tyrosine kinase activity
EXW62_00865	COG2194	sulfuric ester hydrolase activity
EXW62_00870	COG0726	polysaccharide deacetylase
EXW62_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW62_00955	COG4856	YbbR-like protein
EXW62_00970	COG0823	Involved in the tonB-independent uptake of proteins
EXW62_00970	COG4946	Tricorn protease homolog
EXW62_00970	COG1506	peptidase
EXW62_00990	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_00995	COG2011	ABC-type metal ion transport system permease component
EXW62_01005	COG1464	Belongs to the NlpA lipoprotein family
EXW62_01010	COG0604	alcohol dehydrogenase
EXW62_01020	COG0277	FAD linked oxidase domain protein
EXW62_01025	COG2271	Major facilitator Superfamily
EXW62_01035	COG2814	Major facilitator Superfamily
EXW62_01050	COG0601	transmembrane transport
EXW62_01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW62_01060	COG0444	Belongs to the ABC transporter superfamily
EXW62_01065	COG4608	Belongs to the ABC transporter superfamily
EXW62_01070	COG4166	transmembrane transport
EXW62_01085	COG4166	transmembrane transport
EXW62_01090	COG4166	transmembrane transport
EXW62_01095	COG0656	L-ascorbic acid biosynthetic process
EXW62_01100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW62_01110	COG4149	molybdate abc transporter
EXW62_01115	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW62_01120	COG1910	domain protein
EXW62_01135	COG0697	spore germination
EXW62_01150	COG0204	Acyl-transferase
EXW62_01160	COG1609	Transcriptional regulator
EXW62_01170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_01185	COG5298	Protein conserved in bacteria
EXW62_01210	COG0488	(ABC) transporter
EXW62_01225	COG0747	negative chemotaxis
EXW62_01235	COG0601	transmembrane transport
EXW62_01240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW62_01245	COG0444	Belongs to the ABC transporter superfamily
EXW62_01250	COG4608	Belongs to the ABC transporter superfamily
EXW62_01255	COG0561	phosphatase activity
EXW62_01285	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW62_01290	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW62_01300	COG0531	amino acid
EXW62_01305	COG2814	Major facilitator Superfamily
EXW62_01315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW62_01325	COG4294	response to UV
EXW62_01330	COG0705	Rhomboid family
EXW62_01335	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW62_01340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW62_01345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW62_01350	COG0864	Transcriptional regulator
EXW62_01355	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW62_01360	COG2183	response to ionizing radiation
EXW62_01465	COG0802	atpase or kinase
EXW62_01470	COG1214	PFAM Peptidase M22, glycoprotease
EXW62_01475	COG0456	acetyltransferase
EXW62_01485	COG0488	(ABC) transporter
EXW62_01490	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW62_01500	COG1266	CAAX protease self-immunity
EXW62_01505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW62_01510	COG0459	protein refolding
EXW62_01515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW62_01515	COG0519	Catalyzes the synthesis of GMP from XMP
EXW62_01520	COG2252	PERMEase
EXW62_01530	COG5002	protein histidine kinase activity
EXW62_01555	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW62_01615	COG2205	protein histidine kinase activity
EXW62_01620	COG0745	RESPONSE REGULATOR receiver
EXW62_01640	COG0697	spore germination
EXW62_01665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW62_01670	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW62_01675	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW62_01680	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW62_01685	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW62_01695	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW62_01700	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW62_01705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW62_01710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW62_01715	COG0138	bifunctional purine biosynthesis protein purh
EXW62_01725	COG0151	Belongs to the GarS family
EXW62_01745	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW62_01750	COG0210	DNA helicase
EXW62_01755	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW62_01760	COG4851	CamS sex pheromone cAM373 precursor
EXW62_01770	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_01775	COG1335	isochorismatase
EXW62_01785	COG2011	ABC-type metal ion transport system permease component
EXW62_01790	COG1464	Belongs to the NlpA lipoprotein family
EXW62_01805	COG0003	Pfam Anion-transporting ATPase
EXW62_01810	COG1846	Transcriptional regulator
EXW62_01815	COG4682	membrane
EXW62_01825	COG0154	amidase activity
EXW62_01830	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW62_01835	COG1597	lipid kinase activity
EXW62_01845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW62_01860	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_01865	COG2076	Multidrug Resistance protein
EXW62_01875	COG2309	aminopeptidase activity
EXW62_01890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_01900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW62_01905	COG5002	protein histidine kinase activity
EXW62_01910	COG4807	Protein conserved in bacteria
EXW62_01935	COG1757	Na H antiporter
EXW62_01940	COG1473	amidohydrolase
EXW62_01955	COG0450	alkyl hydroperoxide reductase
EXW62_01965	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW62_01975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_01980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_01985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_01995	COG0492	ferredoxin-NADP+ reductase activity
EXW62_02010	COG0166	Belongs to the GPI family
EXW62_02035	COG5002	protein histidine kinase activity
EXW62_02050	COG3541	Predicted nucleotidyltransferase
EXW62_02055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW62_02055	COG0723	plastoquinol--plastocyanin reductase activity
EXW62_02065	COG0765	amino acid transport
EXW62_02070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW62_02075	COG1126	abc transporter atp-binding protein
EXW62_02080	COG0840	transmembrane signaling receptor activity
EXW62_02085	COG0277	FAD linked oxidase domain protein
EXW62_02090	COG0366	Alpha amylase catalytic
EXW62_02095	COG1263	PTS System
EXW62_02095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW62_02095	COG2190	(PTS) system
EXW62_02115	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW62_02125	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW62_02145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW62_02155	COG1116	anion transmembrane transporter activity
EXW62_02160	COG0488	(ABC) transporter
EXW62_02205	COG2270	Major facilitator Superfamily
EXW62_02235	COG2310	stress, protein
EXW62_02240	COG2310	stress, protein
EXW62_02245	COG2310	stress, protein
EXW62_02250	COG0861	Integral membrane protein TerC family
EXW62_02260	COG3853	Toxic anion resistance protein (TelA)
EXW62_02270	COG4840	Belongs to the UPF0435 family
EXW62_02275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW62_02285	COG1295	ribonuclease BN
EXW62_02290	COG2217	Heavy metal translocating P-type atpase
EXW62_02295	COG0697	spore germination
EXW62_02315	COG0586	Pfam SNARE associated Golgi protein
EXW62_02330	COG3871	stress protein (general stress protein 26)
EXW62_02335	COG0387	Pfam Sodium calcium exchanger
EXW62_02345	COG0535	radical SAM domain protein
EXW62_02365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW62_02385	COG3829	transcription factor binding
EXW62_02395	COG0833	amino acid
EXW62_02400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW62_02420	COG2066	Belongs to the glutaminase family
EXW62_02430	COG1263	PTS System
EXW62_02430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW62_02435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW62_02450	COG1216	Glycosyl transferase, family 2
EXW62_02460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW62_02460	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW62_02465	COG0463	Glycosyl transferase, family 2
EXW62_02480	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW62_02485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW62_02500	COG1228	amidohydrolase
EXW62_02505	COG1090	epimerase
EXW62_02510	COG2137	regulation of response to DNA damage stimulus
EXW62_02535	COG1988	membrane-bound metal-dependent
EXW62_02540	COG1194	a g-specific adenine glycosylase
EXW62_02555	COG3557	Belongs to the UPF0374 family
EXW62_02560	COG1132	(ABC) transporter
EXW62_02565	COG4129	membrane
EXW62_02575	COG0070	glutamate synthase
EXW62_02575	COG0069	glutamate synthase activity
EXW62_02575	COG0067	glutamate synthase
EXW62_02580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW62_02585	COG4555	ABC transporter
EXW62_02605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW62_02610	COG0735	belongs to the Fur family
EXW62_02725	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW62_02730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW62_02750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW62_02760	COG2766	serine protein kinase
EXW62_02765	COG2718	Belongs to the UPF0229 family
EXW62_02780	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW62_02785	COG2268	Band 7 protein
EXW62_02795	COG3290	protein histidine kinase activity
EXW62_02800	COG4565	transcriptional regulatory protein
EXW62_02805	COG2851	Citrate transporter
EXW62_02830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW62_02835	COG0745	RESPONSE REGULATOR receiver
EXW62_02840	COG5002	protein histidine kinase activity
EXW62_02850	COG4990	cell redox homeostasis
EXW62_02860	COG3290	protein histidine kinase activity
EXW62_02865	COG4565	transcriptional regulatory protein
EXW62_02870	COG3493	citrate carrier protein
EXW62_02875	COG0281	malic enzyme
EXW62_02885	COG0697	spore germination
EXW62_02890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_02900	COG5002	protein histidine kinase activity
EXW62_02905	COG0745	RESPONSE REGULATOR receiver
EXW62_02910	COG0456	acetyltransferase
EXW62_02920	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW62_02925	COG3383	formate dehydrogenase (NAD+) activity
EXW62_02930	COG2427	Protein of unknown function (DUF1641)
EXW62_02945	COG0531	amino acid
EXW62_02955	COG0640	Transcriptional regulator
EXW62_02960	COG2217	Heavy metal translocating P-type atpase
EXW62_02965	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW62_02975	COG3227	Zinc metalloprotease (Elastase)
EXW62_02995	COG2720	vancomycin resistance protein
EXW62_03000	COG1316	TRANSCRIPTIONal
EXW62_03005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_03010	COG0346	lactoylglutathione lyase activity
EXW62_03015	COG1253	flavin adenine dinucleotide binding
EXW62_03020	COG1027	Aspartate ammonia-lyase
EXW62_03025	COG1620	l-lactate permease
EXW62_03040	COG3104	oligopeptide transport
EXW62_03045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_03050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_03055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_03065	COG0500	methyltransferase
EXW62_03070	COG0156	8-amino-7-oxononanoate synthase activity
EXW62_03075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW62_03085	COG4548	von Willebrand factor, type A
EXW62_03090	COG0714	Associated with various cellular activities
EXW62_03120	COG0531	amino acid
EXW62_03125	COG2188	Transcriptional regulator
EXW62_03130	COG1263	PTS System
EXW62_03130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW62_03135	COG0366	Alpha amylase catalytic
EXW62_03150	COG0697	spore germination
EXW62_03160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW62_03165	COG1115	amino acid carrier protein
EXW62_03175	COG1126	abc transporter atp-binding protein
EXW62_03180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW62_03185	COG0765	amino acid transport
EXW62_03190	COG0765	amino acid transport
EXW62_03195	COG0833	amino acid
EXW62_03230	COG2378	regulation of single-species biofilm formation
EXW62_03235	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW62_03240	COG5002	protein histidine kinase activity
EXW62_03260	COG0659	secondary active sulfate transmembrane transporter activity
EXW62_03275	COG1846	Transcriptional regulator
EXW62_03280	COG0477	Major facilitator Superfamily
EXW62_03285	COG1609	Transcriptional regulator
EXW62_03290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW62_03295	COG1869	D-ribose catabolic process
EXW62_03305	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW62_03310	COG1879	ABC-type sugar transport system periplasmic component
EXW62_03330	COG1063	alcohol dehydrogenase
EXW62_03375	COG0840	transmembrane signaling receptor activity
EXW62_03380	COG3584	3D domain protein
EXW62_03380	COG3583	domain protein
EXW62_03385	COG1476	TRANSCRIPTIONal
EXW62_03405	COG3104	oligopeptide transport
EXW62_03410	COG1114	Component of the transport system for branched-chain amino acids
EXW62_03425	COG1113	amino acid transport
EXW62_03430	COG2252	PERMEase
EXW62_03445	COG2153	protein acetylation
EXW62_03455	COG0475	glutathione-regulated potassium exporter activity
EXW62_03455	COG0569	domain protein
EXW62_03465	COG1845	cytochrome c oxidase, subunit III
EXW62_03470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW62_03475	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EXW62_03480	COG0833	amino acid
EXW62_03485	COG4990	cell redox homeostasis
EXW62_03500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW62_03505	COG0697	spore germination
EXW62_03510	COG0531	amino acid
EXW62_03520	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW62_03525	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW62_03535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW62_03540	COG0573	inorganic phosphate transmembrane transporter activity
EXW62_03545	COG0581	inorganic phosphate transmembrane transporter activity
EXW62_03555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW62_03600	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW62_03680	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW62_03695	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW62_03695	COG4991	sh3 domain protein
EXW62_03695	COG3103	Sh3 type 3 domain protein
EXW62_03700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW62_03705	COG1116	anion transmembrane transporter activity
EXW62_03710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW62_03715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW62_03720	COG0352	thiamine-phosphate diphosphorylase activity
EXW62_03725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW62_03730	COG2104	thiamine diphosphate biosynthetic process
EXW62_03735	COG2022	thiamine diphosphate biosynthetic process
EXW62_03740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW62_03745	COG0351	phosphomethylpyrimidine kinase
EXW62_03765	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW62_03770	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW62_03775	COG2205	protein histidine kinase activity
EXW62_03790	COG2252	PERMEase
EXW62_03795	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_03855	COG0778	Nitroreductase
EXW62_03860	COG2719	SpoVR family
EXW62_03890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW62_03900	COG1937	Protein conserved in bacteria
EXW62_03905	COG0425	Belongs to the sulfur carrier protein TusA family
EXW62_03905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW62_03910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_03910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW62_03915	COG0425	Belongs to the sulfur carrier protein TusA family
EXW62_03920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW62_03925	COG2210	Belongs to the sulfur carrier protein TusA family
EXW62_03930	COG0730	response to heat
EXW62_03940	COG1316	TRANSCRIPTIONal
EXW62_03945	COG0604	alcohol dehydrogenase
EXW62_03950	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW62_03960	COG2814	Major facilitator Superfamily
EXW62_03975	COG3711	transcriptional antiterminator
EXW62_03975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW62_03980	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW62_03985	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW62_04005	COG1388	LysM domain
EXW62_04005	COG3584	3D domain protein
EXW62_04010	COG0577	efflux transmembrane transporter activity
EXW62_04015	COG1136	(ABC) transporter
EXW62_04025	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW62_04040	COG0577	efflux transmembrane transporter activity
EXW62_04045	COG1114	Component of the transport system for branched-chain amino acids
EXW62_04050	COG3546	catalase activity
EXW62_04075	COG0586	Pfam SNARE associated Golgi protein
EXW62_04105	COG0475	glutathione-regulated potassium exporter activity
EXW62_04115	COG1737	Transcriptional regulator
EXW62_04125	COG1263	PTS System
EXW62_04125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW62_04135	COG2259	Doxx family
EXW62_04155	COG0697	spore germination
EXW62_04160	COG1522	sequence-specific DNA binding
EXW62_04185	COG2076	Multidrug Resistance protein
EXW62_04190	COG1309	transcriptional regulator
EXW62_04195	COG2814	Major facilitator Superfamily
EXW62_04200	COG1733	regulation of RNA biosynthetic process
EXW62_04210	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW62_04240	COG4473	ABC transporter
EXW62_04245	COG0531	amino acid
EXW62_04250	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_04265	COG1132	(ABC) transporter
EXW62_04270	COG1132	(ABC) transporter
EXW62_04280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW62_04285	COG0765	amino acid transport
EXW62_04290	COG1126	abc transporter atp-binding protein
EXW62_04305	COG0189	ligase activity
EXW62_04320	COG3679	Belongs to the UPF0342 family
EXW62_04325	COG0028	Belongs to the TPP enzyme family
EXW62_04330	COG3527	Alpha-acetolactate decarboxylase
EXW62_04335	COG0463	Glycosyl transferase, family 2
EXW62_04340	COG1216	Glycosyl transferase, family 2
EXW62_04345	COG2094	Belongs to the DNA glycosylase MPG family
EXW62_04350	COG0561	phosphatase activity
EXW62_04360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW62_04365	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_04375	COG0659	secondary active sulfate transmembrane transporter activity
EXW62_04380	COG2244	polysaccharide biosynthetic process
EXW62_04400	COG1696	Membrane protein involved in D-alanine export
EXW62_04420	COG1024	Enoyl-CoA hydratase
EXW62_04435	COG1363	Peptidase, m42
EXW62_04450	COG2318	DinB family
EXW62_04470	COG0579	oxidoreductase
EXW62_04500	COG0601	transmembrane transport
EXW62_04505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW62_04510	COG0444	Belongs to the ABC transporter superfamily
EXW62_04515	COG4608	Belongs to the ABC transporter superfamily
EXW62_04635	COG0582	viral genome integration into host DNA
EXW62_04720	COG0305	Participates in initiation and elongation during chromosome replication
EXW62_04800	COG2814	Major facilitator Superfamily
EXW62_04805	COG0640	Transcriptional regulator
EXW62_04830	COG2376	Dihydroxyacetone kinase
EXW62_04845	COG2376	Dihydroxyacetone kinase
EXW62_04865	COG2720	vancomycin resistance protein
EXW62_04875	COG1335	isochorismatase
EXW62_04910	COG0076	glutamate decarboxylase activity
EXW62_04965	COG2807	transmembrane transport
EXW62_04970	COG2186	Transcriptional regulator
EXW62_04990	COG4585	Histidine kinase
EXW62_04995	COG2197	response regulator
EXW62_05025	COG0420	3'-5' exonuclease activity
EXW62_05030	COG4717	serine-type aminopeptidase activity
EXW62_05035	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW62_05040	COG0346	lactoylglutathione lyase activity
EXW62_05060	COG2267	carboxylic ester hydrolase activity
EXW62_05070	COG3620	sequence-specific DNA binding
EXW62_05075	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW62_05080	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW62_05085	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW62_05090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW62_05095	COG1595	DNA-templated transcription, initiation
EXW62_05115	COG3973	AAA domain
EXW62_05145	COG0537	adenosine 5'-monophosphoramidase activity
EXW62_05150	COG1131	(ABC) transporter
EXW62_05155	COG4473	ABC transporter
EXW62_05170	COG0247	lactate metabolic process
EXW62_05175	COG1139	Iron-sulfur cluster binding protein
EXW62_05180	COG1556	Lactate utilization protein
EXW62_05195	COG3402	PFAM membrane-flanked domain
EXW62_05200	COG3428	Bacterial PH domain
EXW62_05230	COG3402	PFAM membrane-flanked domain
EXW62_05235	COG3428	Bacterial PH domain
EXW62_05240	COG2329	Antibiotic biosynthesis monooxygenase
EXW62_05245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW62_05250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW62_05255	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW62_05260	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW62_05280	COG1309	transcriptional regulator
EXW62_05285	COG1511	domain protein
EXW62_05330	COG1609	Transcriptional regulator
EXW62_05340	COG1234	tRNA 3'-trailer cleavage
EXW62_05345	COG0095	Lipoate-protein ligase
EXW62_05355	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_05370	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW62_05375	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW62_05380	COG4208	sulfate ABC transporter
EXW62_05415	COG1408	metallophosphoesterase
EXW62_05420	COG1078	dGTPase activity
EXW62_05430	COG1595	DNA-templated transcription, initiation
EXW62_05440	COG2207	Transcriptional regulator
EXW62_05440	COG3708	Transcriptional regulator
EXW62_05445	COG2205	protein histidine kinase activity
EXW62_05450	COG0745	RESPONSE REGULATOR receiver
EXW62_05470	COG0501	Belongs to the peptidase M48B family
EXW62_05475	COG0840	transmembrane signaling receptor activity
EXW62_05480	COG0697	spore germination
EXW62_05505	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW62_05510	COG2224	Isocitrate lyase
EXW62_05520	COG1278	Cold shock
EXW62_05535	COG4903	ComK protein
EXW62_05540	COG0398	Pfam SNARE associated Golgi protein
EXW62_05550	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW62_05555	COG1074	ATP-dependent DNA helicase activity
EXW62_05610	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW62_05635	COG0367	asparagine synthase
EXW62_05645	COG0753	catalase activity
EXW62_05655	COG0004	ammonium transporteR
EXW62_05665	COG1666	GTP binding
EXW62_05670	COG2996	Protein conserved in bacteria
EXW62_05685	COG1329	Transcriptional regulator
EXW62_05720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW62_05730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_05745	COG0561	phosphatase activity
EXW62_05765	COG2267	carboxylic ester hydrolase activity
EXW62_05780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW62_05785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW62_05790	COG5504	Zn-dependent protease
EXW62_05800	COG0180	Tryptophanyl-tRNA synthetase
EXW62_05810	COG4166	transmembrane transport
EXW62_05815	COG0601	transmembrane transport
EXW62_05820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW62_05825	COG0444	Belongs to the ABC transporter superfamily
EXW62_05830	COG4608	Belongs to the ABC transporter superfamily
EXW62_05835	COG0534	Mate efflux family protein
EXW62_05840	COG4166	transmembrane transport
EXW62_05860	COG0861	Integral membrane protein TerC family
EXW62_05865	COG4862	establishment of competence for transformation
EXW62_05870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW62_05880	COG1164	Oligoendopeptidase f
EXW62_05890	COG2346	COG2346, Truncated hemoglobins
EXW62_05895	COG4116	CYTH
EXW62_05905	COG2357	RelA SpoT domain protein
EXW62_05915	COG0564	pseudouridine synthase activity
EXW62_05925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW62_05930	COG0772	Belongs to the SEDS family
EXW62_05935	COG1216	Glycosyl transferase, family 2
EXW62_05955	COG0457	Tetratricopeptide repeat
EXW62_05955	COG0463	Glycosyl transferase, family 2
EXW62_05975	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW62_05990	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW62_06035	COG2153	protein acetylation
EXW62_06045	COG2382	esterase
EXW62_06070	COG5492	domain, Protein
EXW62_06075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW62_06090	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW62_06090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW62_06095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW62_06100	COG0134	indole-3-glycerol-phosphate synthase activity
EXW62_06105	COG0135	phosphoribosylanthranilate isomerase activity
EXW62_06110	COG0133	tryptophan synthase activity
EXW62_06115	COG0159	tryptophan synthase activity
EXW62_06125	COG1620	l-lactate permease
EXW62_06130	COG5634	Uncharacterized conserved protein (DUF2278)
EXW62_06190	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW62_06195	COG0567	Dehydrogenase, E1 component
EXW62_06200	COG1476	TRANSCRIPTIONal
EXW62_06245	COG1686	Belongs to the peptidase S11 family
EXW62_06250	COG0681	Belongs to the peptidase S26 family
EXW62_06285	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_06295	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW62_06300	COG1177	transmembrane transport
EXW62_06305	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW62_06315	COG2409	Drug exporters of the RND superfamily
EXW62_06325	COG0564	pseudouridine synthase activity
EXW62_06335	COG2340	Cysteine-rich secretory protein family
EXW62_06340	COG0247	lactate metabolic process
EXW62_06345	COG0277	FAD linked oxidase domain protein
EXW62_06350	COG3835	regulator
EXW62_06360	COG0745	RESPONSE REGULATOR receiver
EXW62_06365	COG3850	Histidine kinase
EXW62_06365	COG5002	protein histidine kinase activity
EXW62_06370	COG2186	Transcriptional regulator
EXW62_06375	COG0247	lactate metabolic process
EXW62_06380	COG1139	Iron-sulfur cluster binding protein
EXW62_06385	COG1556	Lactate utilization protein
EXW62_06390	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW62_06395	COG2116	formate transmembrane transporter activity
EXW62_06400	COG0861	Integral membrane protein TerC family
EXW62_06405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW62_06415	COG2030	dehydratase
EXW62_06435	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_06440	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW62_06450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW62_06465	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW62_06470	COG3842	ATPase activity
EXW62_06480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW62_06485	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW62_06495	COG1349	DNA-binding transcription factor activity
EXW62_06505	COG0235	Class ii aldolase
EXW62_06515	COG2861	carbohydrate metabolic process
EXW62_06525	COG3852	Histidine kinase
EXW62_06530	COG1846	Transcriptional regulator
EXW62_06540	COG2318	DinB family
EXW62_06545	COG5002	protein histidine kinase activity
EXW62_06555	COG0720	synthase
EXW62_06565	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW62_06570	COG4873	Protein conserved in bacteria
EXW62_06580	COG0456	acetyltransferase
EXW62_06600	COG1780	Probably involved in ribonucleotide reductase function
EXW62_06620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW62_06625	COG0531	amino acid
EXW62_06640	COG2204	response regulator
EXW62_06645	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_06655	COG1725	Transcriptional regulator
EXW62_06660	COG1131	(ABC) transporter
EXW62_06670	COG1131	(ABC) transporter
EXW62_06675	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW62_06690	COG1522	sequence-specific DNA binding
EXW62_06700	COG1335	isochorismatase
EXW62_06710	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW62_06715	COG2070	2-Nitropropane dioxygenase
EXW62_06720	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW62_06725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW62_06730	COG1696	Membrane protein involved in D-alanine export
EXW62_06750	COG0716	FMN binding
EXW62_06760	COG3173	Aminoglycoside phosphotransferase
EXW62_06780	COG1968	undecaprenyl-diphosphatase activity
EXW62_06800	COG1846	Transcriptional regulator
EXW62_06815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW62_06825	COG3874	Sporulation protein YtfJ
EXW62_06850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW62_06855	COG0028	Belongs to the TPP enzyme family
EXW62_06860	COG0440	acetolactate synthase activity
EXW62_06870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW62_06890	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW62_06895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW62_06905	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW62_06910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW62_06915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW62_06920	COG0107	imidazoleglycerol-phosphate synthase activity
EXW62_06930	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW62_06935	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW62_06950	COG1183	phosphatidylcholine synthase activity
EXW62_06955	COG1368	sulfuric ester hydrolase activity
EXW62_06965	COG0019	diaminopimelate decarboxylase activity
EXW62_06985	COG0529	Catalyzes the synthesis of activated sulfate
EXW62_06990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW62_07010	COG1648	precorrin-2 dehydrogenase activity
EXW62_07020	COG0733	neurotransmitter:sodium symporter activity
EXW62_07045	COG1757	Na H antiporter
EXW62_07065	COG4758	membrane
EXW62_07070	COG4585	Histidine kinase
EXW62_07075	COG2197	response regulator
EXW62_07085	COG1114	Component of the transport system for branched-chain amino acids
EXW62_07135	COG0730	response to heat
EXW62_07140	COG0306	phosphate transporter
EXW62_07145	COG1392	Phosphate transport regulator
EXW62_07150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW62_07165	COG3852	Histidine kinase
EXW62_07170	COG1801	Protein of unknown function DUF72
EXW62_07180	COG0582	viral genome integration into host DNA
EXW62_07185	COG5002	protein histidine kinase activity
EXW62_07200	COG0392	lysyltransferase activity
EXW62_07200	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW62_07215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW62_07220	COG1686	Belongs to the peptidase S11 family
EXW62_07225	COG2715	membrane protein required for spore maturation
EXW62_07230	COG0700	Nucleoside recognition
EXW62_07235	COG1187	pseudouridine synthase activity
EXW62_07245	COG1333	cytochrome c biogenesis protein
EXW62_07250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW62_07255	COG0745	RESPONSE REGULATOR receiver
EXW62_07260	COG5002	protein histidine kinase activity
EXW62_07265	COG2096	Adenosyltransferase
EXW62_07280	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW62_07285	COG1141	Ferredoxin
EXW62_07295	COG4955	Helix-turn-helix domain
EXW62_07300	COG0514	ATP-dependent DNA helicase (RecQ)
EXW62_07305	COG1266	CAAX protease self-immunity
EXW62_07315	COG1408	metallophosphoesterase
EXW62_07330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW62_07345	COG0492	ferredoxin-NADP+ reductase activity
EXW62_07350	COG0252	asparaginase activity
EXW62_07355	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW62_07365	COG1304	FMN binding
EXW62_07400	COG1160	GTP binding
EXW62_07405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW62_07425	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW62_07440	COG0142	geranyltranstransferase activity
EXW62_07445	COG2226	methyltransferase
EXW62_07450	COG0142	geranyltranstransferase activity
EXW62_07465	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW62_07475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW62_07480	COG0457	Tetratricopeptide repeat
EXW62_07485	COG5582	Belongs to the UPF0302 family
EXW62_07500	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW62_07505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW62_07505	COG2010	Cytochrome c
EXW62_07510	COG4347	Protein of unknown function (DUF1405)
EXW62_07525	COG2738	Putative neutral zinc metallopeptidase
EXW62_07535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_07540	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW62_07545	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW62_07550	COG1803	Methylglyoxal synthase
EXW62_07555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW62_07560	COG0438	transferase activity, transferring glycosyl groups
EXW62_07565	COG0617	tRNA 3'-terminal CCA addition
EXW62_07575	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW62_07580	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW62_07590	COG1199	ATP-dependent helicase activity
EXW62_07590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW62_07610	COG3935	DnaD domain protein
EXW62_07615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW62_07625	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW62_07625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW62_07630	COG3331	DNA recombination
EXW62_07665	COG4474	Belongs to the UPF0398 family
EXW62_07670	COG3599	regulation of cell shape
EXW62_07680	COG0116	Belongs to the methyltransferase superfamily
EXW62_07690	COG1199	ATP-dependent helicase activity
EXW62_07695	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW62_07700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_07705	COG0024	Methionine aminopeptidase
EXW62_07715	COG2233	PERMEase
EXW62_07725	COG2311	Membrane
EXW62_07730	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW62_07740	COG0456	acetyltransferase
EXW62_07790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW62_07805	COG0454	-acetyltransferase
EXW62_07825	COG0328	RNA-DNA hybrid ribonuclease activity
EXW62_07880	COG3403	YqcI/YcgG family
EXW62_07885	COG1280	lysine exporter protein (LysE YggA)
EXW62_07900	COG3162	membrane
EXW62_07905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW62_07910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW62_07920	COG0475	glutathione-regulated potassium exporter activity
EXW62_07925	COG0789	Transcriptional regulator
EXW62_07925	COG4978	Transcriptional regulator
EXW62_07935	COG2323	membrane
EXW62_07940	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW62_07965	COG2814	Major facilitator Superfamily
EXW62_07985	COG1923	regulation of RNA biosynthetic process
EXW62_07995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW62_08000	COG1360	Flagellar Motor Protein
EXW62_08005	COG2201	protein-glutamate methylesterase activity
EXW62_08010	COG0643	Histidine kinase
EXW62_08010	COG2198	Histidine kinase
EXW62_08015	COG1776	CheC inhibitor of MCP methylation
EXW62_08015	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW62_08030	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW62_08050	COG1256	bacterial-type flagellum assembly
EXW62_08055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW62_08080	COG1815	bacterial-type flagellum-dependent cell motility
EXW62_08085	COG1558	bacterial-type flagellum-dependent cell motility
EXW62_08095	COG1766	The M ring may be actively involved in energy transduction
EXW62_08100	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW62_08110	COG1157	protein secretion by the type III secretion system
EXW62_08130	COG1749	Flagellar hook protein flgE
EXW62_08145	COG0835	chemotaxis
EXW62_08145	COG0784	Response regulator, receiver
EXW62_08170	COG0861	Integral membrane protein TerC family
EXW62_08180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW62_08185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW62_08190	COG0741	lytic transglycosylase activity
EXW62_08200	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW62_08205	COG1776	CheC inhibitor of MCP methylation
EXW62_08205	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW62_08215	COG1338	Plays a role in the flagellum-specific transport system
EXW62_08220	COG1987	bacterial-type flagellum assembly
EXW62_08230	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW62_08235	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW62_08240	COG1419	protein localization to endoplasmic reticulum
EXW62_08245	COG4786	Flagellar basal body rod
EXW62_08275	COG0412	Dienelactone hydrolase
EXW62_08280	COG2329	Antibiotic biosynthesis monooxygenase
EXW62_08310	COG2814	Major facilitator Superfamily
EXW62_08320	COG0583	DNA-binding transcription factor activity
EXW62_08325	COG3842	ATPase activity
EXW62_08365	COG1686	Belongs to the peptidase S11 family
EXW62_08400	COG0367	asparagine synthase
EXW62_08430	COG1802	Transcriptional regulator
EXW62_08435	COG0697	spore germination
EXW62_08450	COG0438	transferase activity, transferring glycosyl groups
EXW62_08450	COG1216	Glycosyl transferase, family 2
EXW62_08455	COG1757	Na H antiporter
EXW62_08465	COG0277	FAD linked oxidase domain protein
EXW62_08480	COG0534	Mate efflux family protein
EXW62_08485	COG3340	Belongs to the peptidase S51 family
EXW62_08505	COG0785	Cytochrome C biogenesis protein
EXW62_08525	COG3048	D-serine ammonia-lyase activity
EXW62_08530	COG2733	membrane
EXW62_08570	COG1131	(ABC) transporter
EXW62_08590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW62_08595	COG0528	UMP kinase activity
EXW62_08605	COG1027	Aspartate ammonia-lyase
EXW62_08610	COG0281	malic enzyme
EXW62_08615	COG4191	Histidine kinase
EXW62_08620	COG0784	Response regulator, receiver
EXW62_08625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW62_08640	COG2502	aspartate--ammonia ligase
EXW62_08675	COG1051	belongs to the nudix hydrolase family
EXW62_08680	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW62_08690	COG2814	Major facilitator Superfamily
EXW62_08715	COG1695	Transcriptional regulator
EXW62_08730	COG0477	Major facilitator Superfamily
EXW62_08750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW62_08755	COG2223	nitrite transmembrane transporter activity
EXW62_08760	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW62_08775	COG2244	polysaccharide biosynthetic process
EXW62_08780	COG0733	neurotransmitter:sodium symporter activity
EXW62_08790	COG5566	PFAM Mor transcription activator
EXW62_08795	COG2323	membrane
EXW62_08810	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW62_08820	COG0129	dihydroxy-acid dehydratase activity
EXW62_08825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW62_08850	COG2814	Major facilitator Superfamily
EXW62_08855	COG3384	dioxygenase
EXW62_08880	COG4166	transmembrane transport
EXW62_08885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_08905	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW62_08910	COG1054	Belongs to the UPF0176 family
EXW62_08920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW62_08925	COG0531	amino acid
EXW62_08950	COG2390	Transcriptional regulator
EXW62_08960	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW62_08965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_08970	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW62_08985	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW62_09005	COG0583	DNA-binding transcription factor activity
EXW62_09020	COG0006	proline dipeptidase activity
EXW62_09025	COG2132	Multicopper oxidase
EXW62_09040	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW62_09045	COG2801	Transposase and inactivated derivatives
EXW62_09055	COG1309	transcriptional regulator
EXW62_09060	COG1131	(ABC) transporter
EXW62_09120	COG1114	Component of the transport system for branched-chain amino acids
EXW62_09130	COG1276	copper resistance
EXW62_09130	COG2372	response to copper ion
EXW62_09135	COG4549	nuclear export factor GLE1
EXW62_09145	COG0697	spore germination
EXW62_09150	COG0583	DNA-binding transcription factor activity
EXW62_09155	COG1959	2 iron, 2 sulfur cluster binding
EXW62_09160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW62_09165	COG0778	Nitroreductase
EXW62_09175	COG0628	permease
EXW62_09190	COG1231	oxidoreductase activity
EXW62_09195	COG0523	cobalamin synthesis protein
EXW62_09205	COG0411	ABC transporter
EXW62_09235	COG1942	4-Oxalocrotonate Tautomerase
EXW62_09250	COG0346	lactoylglutathione lyase activity
EXW62_09260	COG1271	oxidase subunit
EXW62_09265	COG1294	oxidase, subunit
EXW62_09270	COG4988	ABC transporter
EXW62_09275	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW62_09305	COG1686	Belongs to the peptidase S11 family
EXW62_09315	COG0791	NLP P60 protein
EXW62_09315	COG1388	LysM domain
EXW62_09325	COG1132	(ABC) transporter
EXW62_09330	COG0745	RESPONSE REGULATOR receiver
EXW62_09335	COG5002	protein histidine kinase activity
EXW62_09340	COG0300	oxidoreductase activity
EXW62_09345	COG4122	O-methyltransferase activity
EXW62_09375	COG0460	homoserine dehydrogenase
EXW62_09385	COG0083	homoserine kinase activity
EXW62_09400	COG1316	TRANSCRIPTIONal
EXW62_09410	COG0745	RESPONSE REGULATOR receiver
EXW62_09415	COG5002	protein histidine kinase activity
EXW62_09430	COG1285	pathogenesis
EXW62_09435	COG1247	-acetyltransferase
EXW62_09455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW62_09465	COG1082	Xylose isomerase domain protein TIM barrel
EXW62_09475	COG2814	Major facilitator Superfamily
EXW62_09480	COG1279	arginine transmembrane transporter activity
EXW62_09485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_09495	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW62_09525	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW62_09530	COG0577	efflux transmembrane transporter activity
EXW62_09535	COG2002	toxin-antitoxin pair type II binding
EXW62_09540	COG1404	Belongs to the peptidase S8 family
EXW62_09545	COG0640	Transcriptional regulator
EXW62_09550	COG0667	Aldo Keto reductase
EXW62_09575	COG0840	transmembrane signaling receptor activity
EXW62_09590	COG3949	Membrane
EXW62_09595	COG0783	Belongs to the Dps family
EXW62_09610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW62_09620	COG1231	oxidoreductase activity
EXW62_09625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_09630	COG4989	oxidoreductase activity
EXW62_09635	COG0523	cobalamin synthesis protein
EXW62_09660	COG0456	acetyltransferase
EXW62_09665	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW62_09675	COG0702	epimerase
EXW62_09685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW62_09695	COG4166	transmembrane transport
EXW62_09710	COG0406	alpha-ribazole phosphatase activity
EXW62_09720	COG5337	Spore coat protein CotH
EXW62_09725	COG1051	belongs to the nudix hydrolase family
EXW62_09730	COG0586	Pfam SNARE associated Golgi protein
EXW62_09735	COG2244	polysaccharide biosynthetic process
EXW62_09745	COG0701	Predicted permease
EXW62_09750	COG3689	TIGRFAM TIGR03943 family protein
EXW62_09755	COG1607	acyl-coa hydrolase
EXW62_09765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW62_09785	COG0702	epimerase
EXW62_09790	COG2839	Protein conserved in bacteria
EXW62_09795	COG1253	flavin adenine dinucleotide binding
EXW62_09810	COG1114	Component of the transport system for branched-chain amino acids
EXW62_09815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW62_09835	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW62_09845	COG1876	peptidase activity
EXW62_09875	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW62_09885	COG0561	phosphatase activity
EXW62_09890	COG1846	Transcriptional regulator
EXW62_09895	COG2814	Major facilitator Superfamily
EXW62_09905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW62_09925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_09930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_09955	COG0456	acetyltransferase
EXW62_09990	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW62_10065	COG3874	Sporulation protein YtfJ
EXW62_10090	COG2226	methyltransferase
EXW62_10115	COG0346	lactoylglutathione lyase activity
EXW62_10130	COG1595	DNA-templated transcription, initiation
EXW62_10150	COG0426	domain, Protein
EXW62_10150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW62_10160	COG0386	Belongs to the glutathione peroxidase family
EXW62_10165	COG1305	Transglutaminase-like
EXW62_10170	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW62_10175	COG0714	Associated with various cellular activities
EXW62_10180	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW62_10185	COG1140	nitrate reductase beta subunit
EXW62_10190	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW62_10195	COG2181	nitrate reductase activity
EXW62_10200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW62_10205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW62_10210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW62_10220	COG0314	molybdopterin synthase activity
EXW62_10230	COG2223	nitrite transmembrane transporter activity
EXW62_10235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW62_10235	COG1648	precorrin-2 dehydrogenase activity
EXW62_10245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW62_10245	COG1587	Uroporphyrinogen-III synthase
EXW62_10250	COG2146	nitrite reductase [NAD(P)H] activity
EXW62_10255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW62_10260	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW62_10285	COG2359	stage V sporulation protein S
EXW62_10295	COG1418	mRNA catabolic process
EXW62_10300	COG0488	(ABC) transporter
EXW62_10335	COG1413	lyase activity
EXW62_10350	COG2521	methyltransferase
EXW62_10350	COG2136	Putative SAM-dependent methyltransferase
EXW62_10355	COG0018	arginyl-trna synthetase
EXW62_10405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW62_10415	COG0017	Asparaginyl-tRNA synthetase
EXW62_10420	COG0733	neurotransmitter:sodium symporter activity
EXW62_10445	COG2610	gluconate transmembrane transporter activity
EXW62_10450	COG1454	alcohol dehydrogenase
EXW62_10460	COG0456	acetyltransferase
EXW62_10465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW62_10470	COG1131	(ABC) transporter
EXW62_10475	COG4473	ABC transporter
EXW62_10485	COG0546	phosphoglycolate phosphatase activity
EXW62_10535	COG0768	penicillin binding
EXW62_10550	COG1272	protein, Hemolysin III
EXW62_10555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW62_10560	COG0805	protein transport
EXW62_10570	COG1307	EDD domain protein, DegV family
EXW62_10575	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW62_10580	COG1999	signal sequence binding
EXW62_10585	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW62_10590	COG0367	asparagine synthase
EXW62_10605	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW62_10610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_10615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW62_10635	COG1335	isochorismatase
EXW62_10640	COG1051	belongs to the nudix hydrolase family
EXW62_10645	COG0668	transmembrane transport
EXW62_10650	COG2203	Gaf domain
EXW62_10650	COG4585	Histidine kinase
EXW62_10655	COG2197	response regulator
EXW62_10660	COG1737	Transcriptional regulator
EXW62_10665	COG1064	alcohol dehydrogenase
EXW62_10680	COG1070	Carbohydrate kinase
EXW62_10690	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW62_10710	COG1125	glycine betaine transport
EXW62_10710	COG0517	IMP dehydrogenase activity
EXW62_10715	COG1174	glycine betaine transport
EXW62_10750	COG1253	flavin adenine dinucleotide binding
EXW62_10755	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_10760	COG5506	Protein of unknown function (DUF1694)
EXW62_10775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW62_10780	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW62_10785	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW62_10790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW62_10795	COG0456	acetyltransferase
EXW62_10800	COG3829	transcription factor binding
EXW62_10805	COG1509	lysine 2,3-aminomutase activity
EXW62_10815	COG4479	Belongs to the UPF0346 family
EXW62_10840	COG4991	sh3 domain protein
EXW62_10840	COG0515	serine threonine protein kinase
EXW62_10840	COG3064	Membrane
EXW62_10850	COG0671	phosphoesterase, PA-phosphatase related
EXW62_10855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW62_10860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW62_10910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW62_10930	COG4221	oxidoreductase activity
EXW62_10950	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW62_10950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW62_10960	COG2814	Major facilitator Superfamily
EXW62_10970	COG0372	Belongs to the citrate synthase family
EXW62_10975	COG2079	MmgE PrpD family protein
EXW62_10980	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW62_10990	COG1960	acyl-CoA dehydrogenase activity
EXW62_10995	COG2084	Dehydrogenase
EXW62_11000	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_11005	COG1280	lysine exporter protein (LysE YggA)
EXW62_11010	COG1024	Enoyl-CoA hydratase
EXW62_11025	COG0420	3'-5' exonuclease activity
EXW62_11030	COG0419	ATPase involved in DNA repair
EXW62_11035	COG3397	chitin binding
EXW62_11040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW62_11055	COG2223	nitrite transmembrane transporter activity
EXW62_11060	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_11065	COG1169	isochorismate synthase
EXW62_11070	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW62_11075	COG1535	isochorismatase
EXW62_11075	COG3433	isochorismatase activity
EXW62_11080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW62_11085	COG3251	PFAM MbtH domain protein
EXW62_11090	COG2814	Major facilitator Superfamily
EXW62_11105	COG0776	regulation of translation
EXW62_11115	COG1115	amino acid carrier protein
EXW62_11120	COG2329	Antibiotic biosynthesis monooxygenase
EXW62_11135	COG1187	pseudouridine synthase activity
EXW62_11140	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW62_11145	COG3655	Transcriptional regulator
EXW62_11155	COG1136	(ABC) transporter
EXW62_11165	COG0596	Alpha beta hydrolase
EXW62_11180	COG0028	Belongs to the TPP enzyme family
EXW62_11205	COG4974	Belongs to the 'phage' integrase family
EXW62_11225	COG1253	flavin adenine dinucleotide binding
EXW62_11260	COG2267	carboxylic ester hydrolase activity
EXW62_11270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_11305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_11310	COG1309	transcriptional regulator
EXW62_11320	COG0697	spore germination
EXW62_11325	COG0531	amino acid
EXW62_11340	COG1247	-acetyltransferase
EXW62_11380	COG0596	Alpha beta hydrolase
EXW62_11385	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW62_11395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_11420	COG0561	phosphatase activity
EXW62_11430	COG0583	DNA-binding transcription factor activity
EXW62_11435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW62_11445	COG0583	DNA-binding transcription factor activity
EXW62_11450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW62_11455	COG2258	MOSC domain
EXW62_11470	COG1132	(ABC) transporter
EXW62_11475	COG1132	(ABC) transporter
EXW62_11515	COG1396	sequence-specific DNA binding
EXW62_11545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW62_11555	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW62_11560	COG1595	DNA-templated transcription, initiation
EXW62_11580	COG1649	PFAM Uncharacterised BCR, COG1649
EXW62_11600	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW62_11605	COG2971	BadF BadG BcrA BcrD
EXW62_11625	COG1846	Transcriptional regulator
EXW62_11675	COG3615	Tellurite resistance protein tehB
EXW62_11675	COG0500	methyltransferase
EXW62_11685	COG0693	protein deglycase activity
EXW62_11695	COG0588	phosphoglycerate mutase activity
EXW62_11715	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW62_11725	COG0110	maltose O-acetyltransferase activity
EXW62_11730	COG1136	(ABC) transporter
EXW62_11760	COG1686	Belongs to the peptidase S11 family
EXW62_11820	COG0768	penicillin binding
EXW62_11825	COG1595	DNA-templated transcription, initiation
EXW62_11835	COG0768	penicillin binding
EXW62_11840	COG0768	penicillin binding
EXW62_11880	COG1252	NADH dehydrogenase
EXW62_11885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_11885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW62_11900	COG0697	spore germination
EXW62_11935	COG3397	chitin binding
EXW62_11940	COG0823	Involved in the tonB-independent uptake of proteins
EXW62_11950	COG1408	metallophosphoesterase
EXW62_11960	COG1131	(ABC) transporter
EXW62_11970	COG1309	transcriptional regulator
EXW62_11980	COG1960	acyl-CoA dehydrogenase activity
EXW62_11985	COG0439	Biotin carboxylase
EXW62_11990	COG0511	ligase activity, forming carbon-carbon bonds
EXW62_11995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW62_12000	COG1024	Enoyl-CoA hydratase
EXW62_12005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW62_12010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW62_12025	COG3344	reverse transcriptase
EXW62_12070	COG1686	Belongs to the peptidase S11 family
EXW62_12095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW62_12120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW62_12150	COG1733	regulation of RNA biosynthetic process
EXW62_12170	COG1942	4-Oxalocrotonate Tautomerase
EXW62_12175	COG0583	DNA-binding transcription factor activity
EXW62_12185	COG1309	transcriptional regulator
EXW62_12215	COG0697	spore germination
EXW62_12220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_12255	COG2323	membrane
EXW62_12275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_12280	COG0697	spore germination
EXW62_12285	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW62_12290	COG0201	protein transport
EXW62_12300	COG0737	Belongs to the 5'-nucleotidase family
EXW62_12305	COG3227	Zinc metalloprotease (Elastase)
EXW62_12310	COG1523	belongs to the glycosyl hydrolase 13 family
EXW62_12330	COG1073	alpha beta
EXW62_12340	COG0577	efflux transmembrane transporter activity
EXW62_12345	COG1136	(ABC) transporter
EXW62_12365	COG5002	protein histidine kinase activity
EXW62_12370	COG0745	RESPONSE REGULATOR receiver
EXW62_12375	COG1011	Hydrolase
EXW62_12395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW62_12400	COG1183	phosphatidylcholine synthase activity
EXW62_12410	COG1132	(ABC) transporter
EXW62_12420	COG3961	Belongs to the TPP enzyme family
EXW62_12440	COG0322	excinuclease ABC activity
EXW62_12465	COG2318	DinB family
EXW62_12480	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW62_12505	COG3878	Protein conserved in bacteria
EXW62_12545	COG0592	DNA-directed DNA polymerase activity
EXW62_12550	COG2816	NAD+ diphosphatase activity
EXW62_12560	COG2223	nitrite transmembrane transporter activity
EXW62_12565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW62_12605	COG0584	glycerophosphoryl diester phosphodiesterase
EXW62_12620	COG2814	Major facilitator Superfamily
EXW62_12630	COG1132	(ABC) transporter
EXW62_12630	COG2375	cellular response to nickel ion
EXW62_12635	COG1132	(ABC) transporter
EXW62_12670	COG0768	penicillin binding
EXW62_12675	COG0671	phosphoesterase, PA-phosphatase related
EXW62_12680	COG0604	alcohol dehydrogenase
EXW62_12685	COG5002	protein histidine kinase activity
EXW62_12690	COG0745	RESPONSE REGULATOR receiver
EXW62_12700	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW62_12710	COG2205	protein histidine kinase activity
EXW62_12725	COG1122	ATPase activity
EXW62_12730	COG4720	Psort location CytoplasmicMembrane, score
EXW62_12735	COG1794	racemase activity, acting on amino acids and derivatives
EXW62_12745	COG1819	glycosyl
EXW62_12755	COG0768	penicillin binding
EXW62_12760	COG5002	protein histidine kinase activity
EXW62_12765	COG0561	phosphatase activity
EXW62_12805	COG2124	cytochrome p450
EXW62_12835	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW62_12845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_12850	COG0460	homoserine dehydrogenase
EXW62_12870	COG0577	efflux transmembrane transporter activity
EXW62_12875	COG1136	(ABC) transporter
EXW62_12895	COG0488	(ABC) transporter
EXW62_12900	COG0667	Aldo Keto reductase
EXW62_12910	COG2205	protein histidine kinase activity
EXW62_12915	COG0745	RESPONSE REGULATOR receiver
EXW62_12925	COG3773	Cell wall hydrolase
EXW62_12960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_12975	COG2959	enzyme of heme biosynthesis
EXW62_12995	COG3483	tryptophan 2,3-dioxygenase activity
EXW62_13005	COG3844	kynureninase activity
EXW62_13010	COG1309	transcriptional regulator
EXW62_13035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_13040	COG1349	DNA-binding transcription factor activity
EXW62_13080	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_13085	COG0456	acetyltransferase
EXW62_13085	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW62_13120	COG4176	ABC-type proline glycine betaine transport system permease component
EXW62_13125	COG0517	IMP dehydrogenase activity
EXW62_13125	COG4175	Glycine betaine
EXW62_13150	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW62_13155	COG2153	protein acetylation
EXW62_13165	COG1819	glycosyl
EXW62_13180	COG2205	protein histidine kinase activity
EXW62_13185	COG2315	Protein conserved in bacteria
EXW62_13240	COG3973	AAA domain
EXW62_13255	COG0514	ATP-dependent DNA helicase (RecQ)
EXW62_13280	COG4637	Psort location Cytoplasmic, score
EXW62_13300	COG1227	inorganic diphosphatase activity
EXW62_13305	COG2318	DinB family
EXW62_13330	COG1162	GTPase activity
EXW62_13335	COG1115	amino acid carrier protein
EXW62_13340	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_13345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW62_13355	COG3938	Belongs to the proline racemase family
EXW62_13360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW62_13400	COG3214	Protein conserved in bacteria
EXW62_13405	COG2318	DinB family
EXW62_13415	COG0586	Pfam SNARE associated Golgi protein
EXW62_13425	COG4166	transmembrane transport
EXW62_13435	COG4948	Mandelate Racemase Muconate Lactonizing
EXW62_13455	COG0667	Aldo Keto reductase
EXW62_13500	COG2936	dipeptidyl-peptidase activity
EXW62_13510	COG0745	RESPONSE REGULATOR receiver
EXW62_13530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW62_13560	COG1307	EDD domain protein, DegV family
EXW62_13590	COG1335	isochorismatase
EXW62_13605	COG2814	Major facilitator Superfamily
EXW62_13615	COG1664	Polymer-forming cytoskeletal
EXW62_13620	COG0789	Transcriptional regulator
EXW62_13625	COG4533	DNA binding
EXW62_13630	COG2814	Major facilitator Superfamily
EXW62_13630	COG0477	Major facilitator Superfamily
EXW62_13645	COG2261	transglycosylase associated protein
EXW62_13660	COG2226	methyltransferase
EXW62_13695	COG0436	Aminotransferase
EXW62_13700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW62_13725	COG1131	(ABC) transporter
EXW62_13770	COG0628	permease
EXW62_13795	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW62_13815	COG0697	spore germination
EXW62_13835	COG4912	Dna alkylation repair
EXW62_13865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW62_13875	COG2814	Major facilitator Superfamily
EXW62_13880	COG1368	sulfuric ester hydrolase activity
EXW62_13890	COG0488	(ABC) transporter
EXW62_13900	COG1309	transcriptional regulator
EXW62_13915	COG0287	Prephenate dehydrogenase
EXW62_13930	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW62_13930	COG1605	Chorismate mutase
EXW62_13965	COG1388	LysM domain
EXW62_13965	COG3584	3D domain protein
EXW62_13975	COG0346	lactoylglutathione lyase activity
EXW62_13985	COG0431	NADPH-dependent FMN reductase
EXW62_13995	COG1595	DNA-templated transcription, initiation
EXW62_14015	COG0579	oxidoreductase
EXW62_14025	COG2390	Transcriptional regulator
EXW62_14030	COG1070	Carbohydrate kinase
EXW62_14050	COG0346	lactoylglutathione lyase activity
EXW62_14055	COG2329	Antibiotic biosynthesis monooxygenase
EXW62_14075	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW62_14080	COG2207	Transcriptional regulator
EXW62_14095	COG2207	Transcriptional regulator
EXW62_14110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_14115	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW62_14120	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW62_14125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW62_14130	COG3239	Fatty acid desaturase
EXW62_14145	COG3842	ATPase activity
EXW62_14170	COG1175	transmembrane transport
EXW62_14175	COG1349	DNA-binding transcription factor activity
EXW62_14185	COG3655	Transcriptional regulator
EXW62_14210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_14215	COG0346	lactoylglutathione lyase activity
EXW62_14250	COG0714	Associated with various cellular activities
EXW62_14270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW62_14275	COG0753	catalase activity
EXW62_14290	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW62_14315	COG0714	Associated with various cellular activities
EXW62_14325	COG0778	Nitroreductase
EXW62_14330	COG1846	Transcriptional regulator
EXW62_14365	COG2814	Major facilitator Superfamily
EXW62_14395	COG0456	acetyltransferase
EXW62_14410	COG0697	spore germination
EXW62_14415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_14440	COG0814	amino acid
EXW62_14445	COG0697	spore germination
EXW62_14475	COG5002	protein histidine kinase activity
EXW62_14485	COG0642	Histidine kinase
EXW62_14490	COG0745	RESPONSE REGULATOR receiver
EXW62_14495	COG0596	Alpha beta hydrolase
EXW62_14505	COG0456	acetyltransferase
EXW62_14505	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW62_14530	COG0730	response to heat
EXW62_14540	COG0833	amino acid
EXW62_14550	COG4335	DNA alkylation repair
EXW62_14575	COG0768	penicillin binding
EXW62_14585	COG3104	oligopeptide transport
EXW62_14590	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW62_14605	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW62_14610	COG1984	allophanate hydrolase subunit 2
EXW62_14615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW62_14620	COG1414	Transcriptional regulator
EXW62_14640	COG1960	acyl-CoA dehydrogenase activity
EXW62_14665	COG0640	Transcriptional regulator
EXW62_14685	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW62_14710	COG0574	Belongs to the PEP-utilizing enzyme family
EXW62_14710	COG3848	Pyruvate phosphate dikinase
EXW62_14725	COG0730	response to heat
EXW62_14740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW62_14770	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_14770	COG3347	Dehydrogenase
EXW62_14780	COG1070	Carbohydrate kinase
EXW62_14785	COG0235	Class ii aldolase
EXW62_14795	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW62_14805	COG4154	Belongs to the RbsD FucU family
EXW62_14825	COG0798	PFAM Bile acid sodium symporter
EXW62_14830	COG0346	lactoylglutathione lyase activity
EXW62_14835	COG0640	Transcriptional regulator
EXW62_14840	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_14845	COG1522	sequence-specific DNA binding
EXW62_14860	COG0346	lactoylglutathione lyase activity
EXW62_14890	COG0745	RESPONSE REGULATOR receiver
EXW62_14895	COG3850	Histidine kinase
EXW62_14895	COG5002	protein histidine kinase activity
EXW62_14925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW62_14930	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW62_14945	COG2309	aminopeptidase activity
EXW62_14955	COG1690	Belongs to the RtcB family
EXW62_14975	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW62_14990	COG1136	(ABC) transporter
EXW62_14995	COG0577	efflux transmembrane transporter activity
EXW62_15015	COG3850	Histidine kinase
EXW62_15015	COG5002	protein histidine kinase activity
EXW62_15030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_15035	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW62_15050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW62_15110	COG2814	Major facilitator Superfamily
EXW62_15160	COG2849	repeat protein
EXW62_15165	COG5444	nuclease activity
EXW62_15190	COG1876	peptidase activity
EXW62_15195	COG2843	Capsule synthesis protein
EXW62_15210	COG0477	Major facilitator Superfamily
EXW62_15225	COG1846	Transcriptional regulator
EXW62_15230	COG2814	Major facilitator Superfamily
EXW62_15295	COG4257	antibiotic catabolic process
EXW62_15300	COG4187	Peptidase family M20/M25/M40
EXW62_15305	COG1414	Transcriptional regulator
EXW62_15315	COG0833	amino acid
EXW62_15330	COG2031	fatty acid transporter
EXW62_15340	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW62_15390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW62_15395	COG2356	endonuclease I
EXW62_15400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW62_15405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW62_15425	COG1785	Belongs to the alkaline phosphatase family
EXW62_15430	COG0778	Nitroreductase
EXW62_15435	COG1733	regulation of RNA biosynthetic process
EXW62_15450	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_15460	COG1131	(ABC) transporter
EXW62_15485	COG1011	Hydrolase
EXW62_15490	COG2365	Tyrosine phosphatase family
EXW62_15520	COG0628	permease
EXW62_15525	COG2261	transglycosylase associated protein
EXW62_15540	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW62_15550	COG1253	flavin adenine dinucleotide binding
EXW62_15555	COG0789	Transcriptional regulator
EXW62_15565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW62_15590	COG0697	spore germination
EXW62_15595	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW62_15600	COG3813	Protein conserved in bacteria
EXW62_15605	COG4702	Belongs to the UPF0303 family
EXW62_15615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_15630	COG0494	nUDIX hydrolase
EXW62_15645	COG0384	phenazine biosynthesis protein PhzF
EXW62_15655	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_15665	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_15670	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW62_15675	COG1733	regulation of RNA biosynthetic process
EXW62_15680	COG0577	efflux transmembrane transporter activity
EXW62_15685	COG1136	(ABC) transporter
EXW62_15695	COG0745	RESPONSE REGULATOR receiver
EXW62_15700	COG5002	protein histidine kinase activity
EXW62_15700	COG3850	Histidine kinase
EXW62_15715	COG1191	sigma factor activity
EXW62_15750	COG1876	peptidase activity
EXW62_15775	COG0741	lytic transglycosylase activity
EXW62_15835	COG0657	acetylesterase activity
EXW62_15845	COG2814	Major facilitator Superfamily
EXW62_15850	COG1309	transcriptional regulator
EXW62_15860	COG0384	phenazine biosynthesis protein PhzF
EXW62_15880	COG2224	Isocitrate lyase
EXW62_15910	COG0814	amino acid
EXW62_15940	COG1151	hydroxylamine reductase activity
EXW62_16015	COG1695	Transcriptional regulator
EXW62_16020	COG0604	alcohol dehydrogenase
EXW62_16025	COG1113	amino acid transport
EXW62_16115	COG0745	RESPONSE REGULATOR receiver
EXW62_16120	COG5002	protein histidine kinase activity
EXW62_16125	COG2814	Major facilitator Superfamily
EXW62_16135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW62_16140	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_16150	COG0534	Mate efflux family protein
EXW62_16155	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_16160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW62_16175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW62_16180	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW62_16205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_16210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_16215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_16220	COG3739	integral membrane protein
EXW62_16240	COG0583	DNA-binding transcription factor activity
EXW62_16270	COG1193	negative regulation of DNA recombination
EXW62_16290	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW62_16295	COG1164	Oligoendopeptidase f
EXW62_16300	COG2957	Belongs to the agmatine deiminase family
EXW62_16320	COG3781	membrane
EXW62_16335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW62_16370	COG3973	AAA domain
EXW62_16380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW62_16385	COG0640	Transcriptional regulator
EXW62_16390	COG0604	alcohol dehydrogenase
EXW62_16395	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW62_16420	COG2808	Putative FMN-binding domain
EXW62_16430	COG0277	FAD linked oxidase domain protein
EXW62_16460	COG2514	catechol 2,3-dioxygenase activity
EXW62_16465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW62_16470	COG1126	abc transporter atp-binding protein
EXW62_16475	COG0765	amino acid transport
EXW62_16480	COG2720	vancomycin resistance protein
EXW62_16495	COG0110	maltose O-acetyltransferase activity
EXW62_16505	COG1278	Cold shock
EXW62_16515	COG0716	FMN binding
EXW62_16550	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_16560	COG0165	Argininosuccinate lyase
EXW62_16575	COG4145	pantothenate transmembrane transporter activity
EXW62_16585	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_16590	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_16600	COG1657	PFAM Prenyltransferase squalene oxidase
EXW62_16605	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW62_16610	COG2962	Rard protein
EXW62_16615	COG3326	Membrane
EXW62_16620	COG0531	amino acid
EXW62_16655	COG2226	methyltransferase
EXW62_16660	COG4166	transmembrane transport
EXW62_16665	COG4166	transmembrane transport
EXW62_16670	COG4166	transmembrane transport
EXW62_16680	COG1131	(ABC) transporter
EXW62_16690	COG0673	inositol 2-dehydrogenase activity
EXW62_16695	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW62_16700	COG0187	DNA topoisomerase II activity
EXW62_16705	COG1832	CoA-binding protein
EXW62_16710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW62_16715	COG0745	RESPONSE REGULATOR receiver
EXW62_16725	COG1328	CTP reductase activity
EXW62_16735	COG4841	protein insertion into membrane
EXW62_16740	COG0824	Thioesterase
EXW62_16765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW62_16785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW62_16815	COG2211	Major facilitator Superfamily
EXW62_16825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW62_16835	COG0183	Belongs to the thiolase family
EXW62_16840	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_16845	COG1268	BioY protein
EXW62_16850	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_16860	COG1131	(ABC) transporter
EXW62_16865	COG1396	sequence-specific DNA binding
EXW62_16900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_16910	COG5002	protein histidine kinase activity
EXW62_16920	COG0400	carboxylic ester hydrolase activity
EXW62_16930	COG0069	glutamate synthase activity
EXW62_16935	COG1902	pentaerythritol trinitrate reductase activity
EXW62_16940	COG1329	Transcriptional regulator
EXW62_16945	COG0010	Belongs to the arginase family
EXW62_16955	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW62_16960	COG2986	histidine ammonia-lyase
EXW62_16970	COG2226	methyltransferase
EXW62_17000	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW62_17005	COG0785	Cytochrome C biogenesis protein
EXW62_17030	COG1473	amidohydrolase
EXW62_17035	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW62_17040	COG1131	(ABC) transporter
EXW62_17050	COG0583	DNA-binding transcription factor activity
EXW62_17060	COG1346	cytolysis
EXW62_17080	COG3409	Peptidoglycan-binding domain 1 protein
EXW62_17080	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW62_17100	COG1132	(ABC) transporter
EXW62_17105	COG1132	(ABC) transporter
EXW62_17110	COG3763	UPF0154 protein
EXW62_17125	COG3639	organic phosphonate transmembrane transporter activity
EXW62_17130	COG3639	organic phosphonate transmembrane transporter activity
EXW62_17140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW62_17145	COG0737	Belongs to the 5'-nucleotidase family
EXW62_17155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW62_17160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW62_17175	COG1695	Transcriptional regulator
EXW62_17180	COG1132	(ABC) transporter
EXW62_17210	COG0367	asparagine synthase
EXW62_17215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW62_17225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW62_17235	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW62_17235	COG3420	alginic acid biosynthetic process
EXW62_17245	COG1442	glycosyl transferase family 8
EXW62_17250	COG1216	Glycosyl transferase, family 2
EXW62_17250	COG1442	glycosyl transferase family 8
EXW62_17265	COG0297	glycogen (starch) synthase activity
EXW62_17275	COG0438	transferase activity, transferring glycosyl groups
EXW62_17285	COG1215	transferase activity, transferring glycosyl groups
EXW62_17290	COG0438	transferase activity, transferring glycosyl groups
EXW62_17295	COG0438	transferase activity, transferring glycosyl groups
EXW62_17300	COG1086	Polysaccharide biosynthesis protein
EXW62_17305	COG0489	protein tyrosine kinase activity
EXW62_17310	COG3944	biosynthesis protein
EXW62_17315	COG0174	glutamine synthetase
EXW62_17320	COG0789	Transcriptional regulator
EXW62_17325	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW62_17330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW62_17335	COG2860	membrane
EXW62_17340	COG0464	growth
EXW62_17360	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW62_17370	COG1388	LysM domain
EXW62_17370	COG3584	3D domain protein
EXW62_17375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW62_17375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW62_17375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW62_17380	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW62_17385	COG1349	DNA-binding transcription factor activity
EXW62_17390	COG1979	alcohol dehydrogenase
EXW62_17395	COG2322	membrane
EXW62_17410	COG1473	amidohydrolase
EXW62_17415	COG1408	metallophosphoesterase
EXW62_17430	COG2217	Heavy metal translocating P-type atpase
EXW62_17435	COG2608	mercury ion transmembrane transporter activity
EXW62_17440	COG1937	Protein conserved in bacteria
EXW62_17475	COG4566	intracellular signal transduction
EXW62_17485	COG2819	hydrolase of the alpha beta superfamily
EXW62_17490	COG1120	ATPase activity
EXW62_17495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_17500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_17505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_17510	COG0708	Exodeoxyribonuclease III
EXW62_17515	COG2169	Transcriptional regulator
EXW62_17520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW62_17525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW62_17530	COG2706	6-phosphogluconolactonase activity
EXW62_17535	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW62_17540	COG2364	Membrane
EXW62_17560	COG0346	lactoylglutathione lyase activity
EXW62_17565	COG3300	MHYT domain
EXW62_17565	COG5001	Diguanylate cyclase
EXW62_17605	COG1346	cytolysis
EXW62_17615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_17620	COG0596	Alpha beta hydrolase
EXW62_17620	COG2945	thiolester hydrolase activity
EXW62_17625	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW62_17635	COG2188	Transcriptional regulator
EXW62_17640	COG2723	6-phospho-beta-galactosidase activity
EXW62_17645	COG0823	Involved in the tonB-independent uptake of proteins
EXW62_17650	COG3773	Cell wall hydrolase
EXW62_17660	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW62_17680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW62_17690	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW62_17695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW62_17700	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW62_17705	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW62_17705	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW62_17715	COG2359	stage V sporulation protein S
EXW62_17720	COG1692	metallophosphoesterase
EXW62_17725	COG1418	mRNA catabolic process
EXW62_17730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW62_17735	COG1058	Belongs to the CinA family
EXW62_17735	COG1546	Belongs to the CinA family
EXW62_17740	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW62_17745	COG1426	Protein conserved in bacteria
EXW62_17760	COG0300	oxidoreductase activity
EXW62_17765	COG0612	Peptidase, M16
EXW62_17770	COG0612	Peptidase, M16
EXW62_17775	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW62_17780	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW62_17785	COG3845	ABC transporter
EXW62_17790	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW62_17795	COG2188	Transcriptional regulator
EXW62_17805	COG1674	ftsk spoiiie
EXW62_17815	COG0740	serine-type endopeptidase activity
EXW62_17820	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW62_17830	COG0527	aspartate kinase activity
EXW62_17835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW62_17840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW62_17845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW62_17850	COG1873	PFAM PRC-barrel domain
EXW62_17855	COG0612	Peptidase, M16
EXW62_17860	COG0726	polysaccharide deacetylase
EXW62_17865	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW62_17875	COG0196	riboflavin kinase activity
EXW62_17885	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW62_17890	COG1550	Protein conserved in bacteria
EXW62_17895	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW62_17900	COG1358	cellular component organization or biogenesis
EXW62_17905	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW62_17910	COG0195	Participates in both transcription termination and antitermination
EXW62_17940	COG0442	prolyl-tRNA aminoacylation
EXW62_17945	COG0750	zinc metalloprotease
EXW62_17955	COG4589	Belongs to the CDS family
EXW62_17965	COG0233	cytoplasmic translational termination
EXW62_17970	COG0528	UMP kinase activity
EXW62_17975	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW62_17980	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW62_17985	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW62_17990	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW62_17995	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW62_18000	COG4974	Belongs to the 'phage' integrase family
EXW62_18005	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW62_18010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW62_18015	COG0758	DNA mediated transformation
EXW62_18020	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW62_18025	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW62_18030	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW62_18045	COG0335	large ribosomal subunit rRNA binding
EXW62_18050	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW62_18055	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW62_18060	COG1837	Belongs to the UPF0109 family
EXW62_18070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW62_18080	COG0552	protein localization to endoplasmic reticulum
EXW62_18085	COG1196	nuclear chromosome segregation
EXW62_18090	COG0571	ribonuclease III activity
EXW62_18095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW62_18100	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_18105	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW62_18110	COG0416	fatty acid biosynthetic process
EXW62_18115	COG2050	protein possibly involved in aromatic compounds catabolism
EXW62_18115	COG1349	DNA-binding transcription factor activity
EXW62_18120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW62_18125	COG1461	Dihydroxyacetone kinase
EXW62_18130	COG1302	Protein conserved in bacteria
EXW62_18145	COG1564	THIamine pyrophosphokinase
EXW62_18150	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW62_18160	COG0515	serine threonine protein kinase
EXW62_18160	COG2815	serine threonine protein kinase
EXW62_18165	COG0631	protein serine/threonine phosphatase activity
EXW62_18170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW62_18175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW62_18175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW62_18180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW62_18185	COG0242	peptide deformylase activity
EXW62_18190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW62_18195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW62_18200	COG1758	RNA polymerase activity
EXW62_18215	COG1561	YicC-like family, N-terminal region
EXW62_18220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW62_18230	COG0006	proline dipeptidase activity
EXW62_18245	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW62_18265	COG0167	dihydroorotate dehydrogenase activity
EXW62_18270	COG0543	2 iron, 2 sulfur cluster binding
EXW62_18275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW62_18285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW62_18290	COG0540	Belongs to the ATCase OTCase family
EXW62_18300	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW62_18305	COG0564	pseudouridine synthase activity
EXW62_18325	COG3599	regulation of cell shape
EXW62_18330	COG2302	S4 RNA-binding domain
EXW62_18335	COG0762	integral membrane protein
EXW62_18340	COG1799	cell septum assembly
EXW62_18345	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW62_18355	COG1873	PFAM PRC-barrel domain
EXW62_18360	COG1191	sigma factor activity
EXW62_18365	COG1191	sigma factor activity
EXW62_18375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW62_18380	COG0849	cell division
EXW62_18385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW62_18400	COG0772	Belongs to the SEDS family
EXW62_18405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW62_18410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW62_18415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW62_18420	COG0768	penicillin binding
EXW62_18425	COG0768	penicillin binding
EXW62_18435	COG0275	rRNA processing
EXW62_18440	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW62_18445	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW62_18450	COG0454	-acetyltransferase
EXW62_18460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW62_18465	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW62_18470	COG1323	Belongs to the UPF0348 family
EXW62_18475	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW62_18480	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW62_18485	COG3314	Sporulation integral membrane protein YlbJ
EXW62_18495	COG0742	ribosomal rna small subunit methyltransferase
EXW62_18505	COG4471	UPF0298 protein
EXW62_18510	COG3679	Belongs to the UPF0342 family
EXW62_18515	COG0406	alpha-ribazole phosphatase activity
EXW62_18530	COG2340	Cysteine-rich secretory protein family
EXW62_18540	COG3336	cytochrome c oxidase
EXW62_18565	COG0109	protoheme IX farnesyltransferase activity
EXW62_18570	COG1612	heme a metabolic process
EXW62_18575	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW62_18585	COG0772	Belongs to the SEDS family
EXW62_18590	COG4838	Belongs to the UPF0358 family
EXW62_18595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW62_18600	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW62_18610	COG4896	Protein conserved in bacteria
EXW62_18625	COG1217	gtp-binding protein TYPA
EXW62_18635	COG0483	inositol monophosphate 1-phosphatase activity
EXW62_18645	COG4493	Belongs to the UPF0637 family
EXW62_18650	COG4476	Belongs to the UPF0223 family
EXW62_18655	COG1982	Orn Lys Arg decarboxylase major
EXW62_18715	COG0022	dehydrogenase e1 component
EXW62_18720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW62_18730	COG0242	peptide deformylase activity
EXW62_18735	COG0561	phosphatase activity
EXW62_18745	COG5503	Protein of unknown function (DUF1447)
EXW62_18750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW62_18755	COG0569	domain protein
EXW62_18765	COG1473	amidohydrolase
EXW62_18770	COG2171	N-acyltransferase activity
EXW62_18775	COG0583	DNA-binding transcription factor activity
EXW62_18780	COG0517	IMP dehydrogenase activity
EXW62_18790	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW62_18800	COG4703	Protein of unknown function (DUF1797)
EXW62_18815	COG2200	EAL domain
EXW62_18820	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_18825	COG1408	metallophosphoesterase
EXW62_18870	COG2814	Major facilitator Superfamily
EXW62_18880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW62_18890	COG3209	COG3209 Rhs family protein
EXW62_18900	COG2205	protein histidine kinase activity
EXW62_18910	COG0436	Aminotransferase
EXW62_18915	COG1609	Transcriptional regulator
EXW62_18920	COG3833	ABC-type maltose transport systems, permease component
EXW62_18925	COG1175	transmembrane transport
EXW62_18930	COG2182	Extracellular solute-binding protein
EXW62_18940	COG0366	Alpha amylase catalytic
EXW62_18945	COG3842	ATPase activity
EXW62_18990	COG0183	Belongs to the thiolase family
EXW62_19030	COG1695	Transcriptional regulator
EXW62_19035	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_19045	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW62_19055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW62_19060	COG0436	Aminotransferase
EXW62_19065	COG1850	ribulose-bisphosphate carboxylase activity
EXW62_19070	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW62_19075	COG0235	Class ii aldolase
EXW62_19080	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW62_19095	COG2084	Dehydrogenase
EXW62_19105	COG2199	diguanylate cyclase activity
EXW62_19110	COG0778	Nitroreductase
EXW62_19135	COG1263	PTS System
EXW62_19135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW62_19135	COG2190	(PTS) system
EXW62_19140	COG3711	transcriptional antiterminator
EXW62_19150	COG2188	Transcriptional regulator
EXW62_19155	COG0363	glucosamine-6-phosphate deaminase activity
EXW62_19160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW62_19170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW62_19180	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW62_19190	COG1547	Domain of unknown function (DUF309)
EXW62_19200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW62_19205	COG4086	secreted protein
EXW62_19210	COG0561	phosphatase activity
EXW62_19215	COG0697	spore germination
EXW62_19230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW62_19270	COG1686	Belongs to the peptidase S11 family
EXW62_19280	COG1725	Transcriptional regulator
EXW62_19285	COG1131	(ABC) transporter
EXW62_19305	COG1846	Transcriptional regulator
EXW62_19320	COG0598	Magnesium transport protein CorA
EXW62_19335	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW62_19345	COG4974	Belongs to the 'phage' integrase family
EXW62_19355	COG0735	belongs to the Fur family
EXW62_19360	COG1300	Membrane
EXW62_19385	COG0667	Aldo Keto reductase
EXW62_19390	COG0656	L-ascorbic acid biosynthetic process
EXW62_19395	COG0456	acetyltransferase
EXW62_19395	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW62_19405	COG0737	Belongs to the 5'-nucleotidase family
EXW62_19405	COG1525	nuclease
EXW62_19405	COG4085	toxin activity
EXW62_19410	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW62_19420	COG0596	Alpha beta hydrolase
EXW62_19425	COG2056	Na+-H+ antiporter family
EXW62_19430	COG1609	Transcriptional regulator
EXW62_19435	COG0456	acetyltransferase
EXW62_19440	COG1073	alpha beta
EXW62_19460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW62_19460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW62_19465	COG0307	riboflavin synthase, alpha
EXW62_19470	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW62_19470	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW62_19485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW62_19490	COG4106	trans-aconitate 2-methyltransferase activity
EXW62_19495	COG1073	alpha beta
EXW62_19495	COG2226	methyltransferase
EXW62_19500	COG0156	8-amino-7-oxononanoate synthase activity
EXW62_19510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW62_19525	COG1757	Na H antiporter
EXW62_19530	COG0737	Belongs to the 5'-nucleotidase family
EXW62_19540	COG1522	sequence-specific DNA binding
EXW62_19560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW62_19565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW62_19575	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW62_19585	COG0300	oxidoreductase activity
EXW62_19590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_19595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW62_19600	COG1760	l-serine dehydratase
EXW62_19605	COG1760	l-serine dehydratase
EXW62_19615	COG1234	tRNA 3'-trailer cleavage
EXW62_19630	COG1285	pathogenesis
EXW62_19645	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW62_19650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_19660	COG1376	ErfK ybiS ycfS ynhG family protein
EXW62_19665	COG4129	membrane
EXW62_19670	COG1126	abc transporter atp-binding protein
EXW62_19675	COG0765	amino acid transport
EXW62_19680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW62_19695	COG2816	NAD+ diphosphatase activity
EXW62_19700	COG2323	membrane
EXW62_19705	COG0772	Belongs to the SEDS family
EXW62_19715	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW62_19720	COG0022	dehydrogenase e1 component
EXW62_19725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW62_19730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW62_19735	COG3426	butyrate kinase activity
EXW62_19745	COG0280	phosphate acetyltransferase
EXW62_19755	COG3290	protein histidine kinase activity
EXW62_19755	COG3829	transcription factor binding
EXW62_19765	COG0584	glycerophosphoryl diester phosphodiesterase
EXW62_19770	COG3093	addiction module antidote protein HigA
EXW62_19820	COG0582	viral genome integration into host DNA
EXW62_19870	COG0745	RESPONSE REGULATOR receiver
EXW62_19880	COG0750	zinc metalloprotease
EXW62_19885	COG0497	DNA recombination
EXW62_19890	COG1438	arginine binding
EXW62_19895	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW62_19900	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW62_19905	COG0142	geranyltranstransferase activity
EXW62_19910	COG1722	exodeoxyribonuclease VII activity
EXW62_19920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW62_19925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW62_19930	COG1302	Protein conserved in bacteria
EXW62_19935	COG0439	Biotin carboxylase
EXW62_19940	COG0511	ligase activity, forming carbon-carbon bonds
EXW62_19985	COG3854	ATPases associated with a variety of cellular activities
EXW62_20005	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW62_20010	COG0006	proline dipeptidase activity
EXW62_20025	COG3872	metal-dependent enzyme
EXW62_20035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW62_20070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW62_20080	COG1609	Transcriptional regulator
EXW62_20090	COG2076	Multidrug Resistance protein
EXW62_20095	COG2076	Multidrug Resistance protein
EXW62_20130	COG1725	Transcriptional regulator
EXW62_20145	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW62_20155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW62_20160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW62_20190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW62_20220	COG4970	Tfp pilus assembly protein FimT
EXW62_20225	COG4537	Required for transformation and DNA binding
EXW62_20230	COG1459	type II secretion system
EXW62_20235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW62_20290	COG0646	methionine synthase
EXW62_20290	COG1410	methionine synthase
EXW62_20295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW62_20295	COG0646	methionine synthase
EXW62_20300	COG0626	cystathionine gamma-synthase activity
EXW62_20305	COG0626	cystathionine gamma-synthase activity
EXW62_20325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_20335	COG1940	carbohydrate kinase activity
EXW62_20340	COG4483	Protein conserved in bacteria
EXW62_20345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW62_20350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW62_20355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW62_20360	COG0704	Plays a role in the regulation of phosphate uptake
EXW62_20370	COG0581	inorganic phosphate transmembrane transporter activity
EXW62_20375	COG0573	inorganic phosphate transmembrane transporter activity
EXW62_20380	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW62_20385	COG0768	penicillin binding
EXW62_20390	COG0477	Major facilitator Superfamily
EXW62_20395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW62_20415	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW62_20420	COG0735	belongs to the Fur family
EXW62_20425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW62_20430	COG1121	(ABC) transporter
EXW62_20435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_20460	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW62_20465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW62_20470	COG2384	SAM-dependent methyltransferase
EXW62_20480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW62_20485	COG0358	DNA primase activity
EXW62_20495	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW62_20500	COG0517	IMP dehydrogenase activity
EXW62_20505	COG1381	Involved in DNA repair and RecF pathway recombination
EXW62_20515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW62_20520	COG0295	cytidine deaminase activity
EXW62_20525	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW62_20530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW62_20535	COG1480	7TM receptor with intracellular HD hydrolase
EXW62_20540	COG1702	phosphate starvation-inducible protein PhoH
EXW62_20555	COG1610	YqeY-like protein
EXW62_20560	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW62_20565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW62_20570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW62_20580	COG0484	heat shock protein binding
EXW62_20585	COG0443	Heat shock 70 kDa protein
EXW62_20595	COG1420	regulation of RNA biosynthetic process
EXW62_20600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW62_20605	COG1733	regulation of RNA biosynthetic process
EXW62_20610	COG0481	GTPase activity
EXW62_20620	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW62_20625	COG0268	Binds directly to 16S ribosomal RNA
EXW62_20630	COG1466	dna polymerase III delta subunit
EXW62_20640	COG0658	competence protein
EXW62_20640	COG2333	competence protein COMEC
EXW62_20645	COG2131	deaminase
EXW62_20650	COG1596	polysaccharide export
EXW62_20650	COG1555	photosystem II stabilization
EXW62_20655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW62_20660	COG2226	methyltransferase
EXW62_20665	COG0799	negative regulation of ribosome biogenesis
EXW62_20670	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW62_20675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW62_20680	COG1534	Rna-binding protein
EXW62_20685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW62_20690	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW62_20695	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW62_20705	COG0688	phosphatidylethanolamine metabolic process
EXW62_20725	COG2357	RelA SpoT domain protein
EXW62_20735	COG1785	Belongs to the alkaline phosphatase family
EXW62_20745	COG2267	carboxylic ester hydrolase activity
EXW62_20780	COG1404	Belongs to the peptidase S8 family
EXW62_20785	COG3186	Phenylalanine-4-hydroxylase
EXW62_20790	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW62_20795	COG2514	catechol 2,3-dioxygenase activity
EXW62_20800	COG2259	Doxx family
EXW62_20840	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW62_20850	COG1454	alcohol dehydrogenase
EXW62_20850	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_20855	COG0626	cystathionine gamma-synthase activity
EXW62_20860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW62_20865	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW62_20870	COG2226	methyltransferase
EXW62_20885	COG0768	penicillin binding
EXW62_20890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW62_20895	COG0572	uridine kinase
EXW62_20900	COG0826	peptidase U32
EXW62_20905	COG0826	peptidase U32
EXW62_20910	COG4122	O-methyltransferase activity
EXW62_20915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW62_20925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW62_20935	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW62_20940	COG0628	permease
EXW62_20960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW62_20970	COG0482	sulfurtransferase activity
EXW62_20975	COG1104	cysteine desulfurase activity
EXW62_20980	COG1959	2 iron, 2 sulfur cluster binding
EXW62_20985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW62_20995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW62_21000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW62_21010	COG1490	D-aminoacyl-tRNA deacylase activity
EXW62_21015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW62_21020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW62_21025	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW62_21025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW62_21030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW62_21035	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW62_21035	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW62_21045	COG2244	polysaccharide biosynthetic process
EXW62_21050	COG2323	membrane
EXW62_21060	COG1862	Preprotein translocase
EXW62_21065	COG0343	queuine tRNA-ribosyltransferase activity
EXW62_21080	COG2255	four-way junction helicase activity
EXW62_21085	COG0632	four-way junction helicase activity
EXW62_21090	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW62_21115	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW62_21120	COG0157	Belongs to the NadC ModD family
EXW62_21125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW62_21130	COG1104	cysteine desulfurase activity
EXW62_21135	COG1827	regulation of RNA biosynthetic process
EXW62_21145	COG2258	MOSC domain
EXW62_21155	COG0077	Prephenate dehydratase
EXW62_21160	COG0577	efflux transmembrane transporter activity
EXW62_21165	COG0577	efflux transmembrane transporter activity
EXW62_21170	COG1136	(ABC) transporter
EXW62_21175	COG5002	protein histidine kinase activity
EXW62_21180	COG0745	RESPONSE REGULATOR receiver
EXW62_21185	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW62_21190	COG3290	protein histidine kinase activity
EXW62_21200	COG2868	ribosomal protein
EXW62_21210	COG1530	ribonuclease E activity
EXW62_21215	COG1994	Peptidase M50
EXW62_21220	COG0739	heme binding
EXW62_21225	COG2894	cell division
EXW62_21230	COG0850	regulation of cytokinetic process
EXW62_21240	COG1792	Involved in formation and maintenance of cell shape
EXW62_21245	COG1077	Cell shape determining protein MreB Mrl
EXW62_21250	COG2003	Belongs to the UPF0758 family
EXW62_21255	COG0424	maF-like protein
EXW62_21270	COG0285	dihydrofolate synthase activity
EXW62_21300	COG1388	LysM domain
EXW62_21305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW62_21310	COG0113	porphobilinogen synthase activity
EXW62_21315	COG1587	Uroporphyrinogen-III synthase
EXW62_21320	COG0181	hydroxymethylbilane synthase activity
EXW62_21325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW62_21330	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW62_21335	COG1846	Transcriptional regulator
EXW62_21340	COG1764	response to oxidative stress
EXW62_21345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW62_21355	COG0470	DNA polymerase III
EXW62_21355	COG1067	ATP-dependent peptidase activity
EXW62_21365	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW62_21395	COG0622	Phosphoesterase
EXW62_21405	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW62_21410	COG5401	PFAM Sporulation and spore germination
EXW62_21420	COG2197	response regulator
EXW62_21425	COG2233	PERMEase
EXW62_21430	COG0402	S-adenosylhomocysteine deaminase activity
EXW62_21435	COG1983	PspC domain protein
EXW62_21440	COG1396	sequence-specific DNA binding
EXW62_21445	COG0697	spore germination
EXW62_21455	COG1959	2 iron, 2 sulfur cluster binding
EXW62_21460	COG1668	transmembrane transport
EXW62_21465	COG4152	abc transporter atp-binding protein
EXW62_21470	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW62_21475	COG1360	Flagellar Motor Protein
EXW62_21480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW62_21490	COG1876	peptidase activity
EXW62_21495	COG0824	Thioesterase
EXW62_21500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW62_21505	COG1053	succinate dehydrogenase
EXW62_21510	COG2009	succinate dehydrogenase
EXW62_21515	COG1719	4-vinyl reductase, 4VR
EXW62_21520	COG0322	excinuclease ABC activity
EXW62_21525	COG3118	belongs to the thioredoxin family
EXW62_21530	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW62_21535	COG2086	electron transfer activity
EXW62_21540	COG1024	Enoyl-CoA hydratase
EXW62_21545	COG1309	transcriptional regulator
EXW62_21550	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_21570	COG2318	DinB family
EXW62_21595	COG1131	(ABC) transporter
EXW62_21600	COG2205	protein histidine kinase activity
EXW62_21605	COG0745	RESPONSE REGULATOR receiver
EXW62_21610	COG4895	conserved protein (DUF2196)
EXW62_21615	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW62_21625	COG4509	Sortase family
EXW62_21630	COG1120	ATPase activity
EXW62_21645	COG5386	Cell surface protein
EXW62_21655	COG5386	Cell surface protein
EXW62_21660	COG1114	Component of the transport system for branched-chain amino acids
EXW62_21665	COG1187	pseudouridine synthase activity
EXW62_21670	COG1193	negative regulation of DNA recombination
EXW62_21675	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW62_21675	COG1796	DNA polymerase
EXW62_21680	COG1286	toxin biosynthetic process
EXW62_21685	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW62_21690	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW62_21715	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW62_21720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW62_21730	COG1418	mRNA catabolic process
EXW62_21740	COG2814	Major facilitator Superfamily
EXW62_21745	COG1566	PFAM secretion protein HlyD family protein
EXW62_21750	COG1309	transcriptional regulator
EXW62_21755	COG1363	Peptidase, m42
EXW62_21765	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW62_21780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW62_21790	COG1484	DNA-dependent DNA replication
EXW62_21795	COG3611	Membrane attachment protein
EXW62_21800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW62_21805	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW62_21810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW62_21820	COG1971	Probably functions as a manganese efflux pump
EXW62_21830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW62_21830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW62_21835	COG5002	protein histidine kinase activity
EXW62_21840	COG0745	RESPONSE REGULATOR receiver
EXW62_21860	COG0538	isocitrate dehydrogenase activity
EXW62_21865	COG0372	Belongs to the citrate synthase family
EXW62_21880	COG0628	permease
EXW62_21885	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW62_21895	COG0205	6-phosphofructokinase activity
EXW62_21910	COG1725	Transcriptional regulator
EXW62_21915	COG0281	malic enzyme
EXW62_21920	COG0587	DNA-directed DNA polymerase activity
EXW62_21935	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW62_21955	COG4109	DRTGG domain
EXW62_21960	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW62_21965	COG0006	proline dipeptidase activity
EXW62_22000	COG1476	TRANSCRIPTIONal
EXW62_22015	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_22020	COG0589	response to stress
EXW62_22040	COG0165	Argininosuccinate lyase
EXW62_22045	COG0137	argininosuccinate synthase activity
EXW62_22060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_22075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW62_22080	COG0827	DNA restriction-modification system
EXW62_22085	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW62_22090	COG3874	Sporulation protein YtfJ
EXW62_22105	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW62_22115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW62_22130	COG1104	cysteine desulfurase activity
EXW62_22135	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW62_22150	COG1309	transcriptional regulator
EXW62_22155	COG1956	GAF domain-containing protein
EXW62_22160	COG0626	cystathionine gamma-synthase activity
EXW62_22165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW62_22195	COG1595	DNA-templated transcription, initiation
EXW62_22205	COG0110	maltose O-acetyltransferase activity
EXW62_22210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW62_22215	COG0454	-acetyltransferase
EXW62_22220	COG0517	IMP dehydrogenase activity
EXW62_22225	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW62_22250	COG5002	protein histidine kinase activity
EXW62_22255	COG0666	response to abiotic stimulus
EXW62_22265	COG1970	mechanosensitive ion channel activity
EXW62_22285	COG1609	Transcriptional regulator
EXW62_22290	COG4851	CamS sex pheromone cAM373 precursor
EXW62_22295	COG3118	belongs to the thioredoxin family
EXW62_22305	COG2309	aminopeptidase activity
EXW62_22325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_22330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW62_22340	COG1674	ftsk spoiiie
EXW62_22355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW62_22360	COG4848	Belongs to the UPF0354 family
EXW62_22365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW62_22370	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW62_22375	COG1363	Peptidase, m42
EXW62_22385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_22390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW62_22400	COG0510	thiamine kinase activity
EXW62_22405	COG1523	belongs to the glycosyl hydrolase 13 family
EXW62_22415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW62_22420	COG1349	DNA-binding transcription factor activity
EXW62_22425	COG1187	pseudouridine synthase activity
EXW62_22430	COG2244	polysaccharide biosynthetic process
EXW62_22435	COG2081	HI0933 family
EXW62_22440	COG2814	Major facilitator Superfamily
EXW62_22450	COG3832	glyoxalase III activity
EXW62_22470	COG1329	Transcriptional regulator
EXW62_22495	COG0314	molybdopterin synthase activity
EXW62_22500	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW62_22505	COG0303	'Molybdopterin
EXW62_22510	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW62_22515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW62_22520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW62_22545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW62_22555	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW62_22595	COG0495	leucyl-tRNA aminoacylation
EXW62_22600	COG2814	Major facilitator Superfamily
EXW62_22605	COG0475	glutathione-regulated potassium exporter activity
EXW62_22610	COG0490	domain, Protein
EXW62_22615	COG0582	viral genome integration into host DNA
EXW62_22630	COG1136	(ABC) transporter
EXW62_22650	COG1242	4 iron, 4 sulfur cluster binding
EXW62_22655	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW62_22665	COG1794	racemase activity, acting on amino acids and derivatives
EXW62_22680	COG2267	carboxylic ester hydrolase activity
EXW62_22685	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW62_22690	COG0671	phosphoesterase, PA-phosphatase related
EXW62_22695	COG0438	transferase activity, transferring glycosyl groups
EXW62_22705	COG1404	Belongs to the peptidase S8 family
EXW62_22710	COG2197	response regulator
EXW62_22715	COG4585	Histidine kinase
EXW62_22720	COG0746	molybdenum cofactor guanylyltransferase activity
EXW62_22740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW62_22745	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW62_22775	COG5002	protein histidine kinase activity
EXW62_22780	COG3852	Histidine kinase
EXW62_22785	COG0753	catalase activity
EXW62_22790	COG2267	carboxylic ester hydrolase activity
EXW62_22795	COG1368	sulfuric ester hydrolase activity
EXW62_22840	COG1278	Cold shock
EXW62_22855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW62_22860	COG1116	anion transmembrane transporter activity
EXW62_22865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW62_22885	COG0494	nUDIX hydrolase
EXW62_22935	COG0288	reversible hydration of carbon dioxide
EXW62_22940	COG1271	oxidase subunit
EXW62_22945	COG1294	oxidase, subunit
EXW62_22960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_22990	COG1842	Phage shock protein A
EXW62_23015	COG3859	Proton-coupled thiamine transporter YuaJ
EXW62_23020	COG5002	protein histidine kinase activity
EXW62_23025	COG0745	RESPONSE REGULATOR receiver
EXW62_23055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW62_23060	COG1597	lipid kinase activity
EXW62_23100	COG1136	(ABC) transporter
EXW62_23130	COG5002	protein histidine kinase activity
EXW62_23155	COG0577	efflux transmembrane transporter activity
EXW62_23160	COG1136	(ABC) transporter
EXW62_23165	COG3708	Transcriptional regulator
EXW62_23165	COG2207	Transcriptional regulator
EXW62_23175	COG1131	(ABC) transporter
EXW62_23180	COG5658	integral membrane protein
EXW62_23185	COG0640	Transcriptional regulator
EXW62_23190	COG0745	RESPONSE REGULATOR receiver
EXW62_23195	COG2205	protein histidine kinase activity
EXW62_23200	COG0577	efflux transmembrane transporter activity
EXW62_23205	COG0577	efflux transmembrane transporter activity
EXW62_23210	COG1136	(ABC) transporter
EXW62_23215	COG0577	efflux transmembrane transporter activity
EXW62_23230	COG2188	Transcriptional regulator
EXW62_23250	COG3964	amidohydrolase
EXW62_23270	COG4948	Mandelate Racemase Muconate Lactonizing
EXW62_23275	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_23280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW62_23285	COG0596	Alpha beta hydrolase
EXW62_23290	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW62_23295	COG1169	isochorismate synthase
EXW62_23300	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW62_23305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW62_23310	COG1278	Cold shock
EXW62_23330	COG0058	SHG alpha-glucan phosphorylase activity
EXW62_23340	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW62_23345	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW62_23350	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW62_23505	COG1285	pathogenesis
EXW62_23510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW62_23520	COG0166	Belongs to the GPI family
EXW62_23530	COG2155	Conserved Protein
EXW62_23535	COG1098	S1 RNA binding domain
EXW62_23540	COG0436	Aminotransferase
EXW62_23545	COG1522	sequence-specific DNA binding
EXW62_23550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW62_23555	COG2267	carboxylic ester hydrolase activity
EXW62_23565	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW62_23580	COG5018	Exonuclease
EXW62_23585	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW62_23605	COG2050	protein possibly involved in aromatic compounds catabolism
EXW62_23615	COG1268	BioY protein
EXW62_23620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW62_23625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW62_23635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW62_23640	COG3584	3D domain protein
EXW62_23655	COG1252	NADH dehydrogenase
EXW62_23660	COG0492	ferredoxin-NADP+ reductase activity
EXW62_23665	COG3708	Transcriptional regulator
EXW62_23680	COG1683	Conserved Protein
EXW62_23695	COG0316	Belongs to the HesB IscA family
EXW62_23700	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW62_23705	COG4844	belongs to the
EXW62_23710	COG1252	NADH dehydrogenase
EXW62_23720	COG2274	protein secretion by the type I secretion system
EXW62_23725	COG0390	transport system, permease component
EXW62_23730	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW62_23760	COG4837	Protein of unknown function (DUF1462)
EXW62_23765	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW62_23780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW62_23785	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW62_23800	COG0647	UMP catabolic process
EXW62_23810	COG2445	Protein of unknown function DUF86
EXW62_23815	COG1494	fructose-1,6-bisphosphatase
EXW62_23835	COG4470	Protein conserved in bacteria
EXW62_23845	COG0789	Transcriptional regulator
EXW62_23850	COG4377	Putative membrane peptidase family (DUF2324)
EXW62_23875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW62_23880	COG0739	heme binding
EXW62_23890	COG3377	Domain of unknown function (DUF1805)
EXW62_23895	COG0737	Belongs to the 5'-nucleotidase family
EXW62_23905	COG0719	Fe-S assembly protein
EXW62_23910	COG0822	iron-sulfur transferase activity
EXW62_23915	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW62_23920	COG0719	Fe-S assembly protein
EXW62_23925	COG0396	ATPase activity
EXW62_23930	COG1464	Belongs to the NlpA lipoprotein family
EXW62_23935	COG1464	Belongs to the NlpA lipoprotein family
EXW62_23940	COG2011	ABC-type metal ion transport system permease component
EXW62_23955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW62_23960	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW62_23965	COG0509	glycine decarboxylation via glycine cleavage system
EXW62_23970	COG1393	Belongs to the ArsC family
EXW62_24005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_24010	COG1960	acyl-CoA dehydrogenase activity
EXW62_24015	COG0183	Belongs to the thiolase family
EXW62_24020	COG1024	Enoyl-CoA hydratase
EXW62_24020	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW62_24030	COG1686	Belongs to the peptidase S11 family
EXW62_24035	COG0506	proline dehydrogenase activity
EXW62_24045	COG0011	TIGRFAM Protein of
EXW62_24050	COG0840	transmembrane signaling receptor activity
EXW62_24065	COG2814	Major facilitator Superfamily
EXW62_24070	COG0531	amino acid
EXW62_24095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_24135	COG0586	Pfam SNARE associated Golgi protein
EXW62_24145	COG1376	ErfK ybiS ycfS ynhG family protein
EXW62_24150	COG0745	RESPONSE REGULATOR receiver
EXW62_24155	COG5002	protein histidine kinase activity
EXW62_24165	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW62_24175	COG0840	transmembrane signaling receptor activity
EXW62_24185	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW62_24190	COG3227	Zinc metalloprotease (Elastase)
EXW62_24210	COG0586	Pfam SNARE associated Golgi protein
EXW62_24215	COG0475	glutathione-regulated potassium exporter activity
EXW62_24220	COG0490	domain, Protein
EXW62_24225	COG1115	amino acid carrier protein
EXW62_24230	COG0783	Belongs to the Dps family
EXW62_24245	COG2318	DinB family
EXW62_24250	COG1611	Belongs to the LOG family
EXW62_24260	COG1528	Iron-storage protein
EXW62_24265	COG2311	Membrane
EXW62_24270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_24275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_24280	COG1115	amino acid carrier protein
EXW62_24285	COG2910	NAD(P)H-binding
EXW62_24295	COG0656	L-ascorbic acid biosynthetic process
EXW62_24300	COG2814	Major facilitator Superfamily
EXW62_24305	COG1733	regulation of RNA biosynthetic process
EXW62_24315	COG1252	NADH dehydrogenase
EXW62_24335	COG0840	transmembrane signaling receptor activity
EXW62_24335	COG3290	protein histidine kinase activity
EXW62_24345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW62_24365	COG3655	Transcriptional regulator
EXW62_24380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_24395	COG1522	sequence-specific DNA binding
EXW62_24400	COG0288	reversible hydration of carbon dioxide
EXW62_24405	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW62_24410	COG2233	PERMEase
EXW62_24435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_24450	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW62_24455	COG0557	exoribonuclease II activity
EXW62_24460	COG1647	Serine aminopeptidase, S33
EXW62_24465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW62_24470	COG1346	cytolysis
EXW62_24495	COG0149	triose-phosphate isomerase activity
EXW62_24500	COG0126	phosphoglycerate kinase activity
EXW62_24505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW62_24520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW62_24545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW62_24560	COG2323	membrane
EXW62_24575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW62_24580	COG1481	regulation of sporulation
EXW62_24585	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW62_24590	COG1660	Displays ATPase and GTPase activities
EXW62_24595	COG1051	belongs to the nudix hydrolase family
EXW62_24605	COG0492	ferredoxin-NADP+ reductase activity
EXW62_24610	COG0457	Tetratricopeptide repeat
EXW62_24615	COG0110	maltose O-acetyltransferase activity
EXW62_24620	COG0546	phosphoglycolate phosphatase activity
EXW62_24625	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW62_24630	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW62_24635	COG1950	PFAM Membrane protein of
EXW62_24640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW62_24655	COG0789	Transcriptional regulator
EXW62_24690	COG0583	DNA-binding transcription factor activity
EXW62_24695	COG0789	Transcriptional regulator
EXW62_24700	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW62_24705	COG0488	(ABC) transporter
EXW62_24715	COG1132	(ABC) transporter
EXW62_24720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW62_24725	COG0793	Belongs to the peptidase S41A family
EXW62_24725	COG3409	Peptidoglycan-binding domain 1 protein
EXW62_24730	COG2177	Part of the ABC transporter FtsEX involved in
EXW62_24735	COG2884	Cell division ATP-binding protein ftsE
EXW62_24770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EXW62_24775	COG1278	Cold shock
EXW62_24780	COG1040	competence protein
EXW62_24785	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW62_24790	COG1388	LysM domain
EXW62_24790	COG0791	NLP P60 protein
EXW62_24795	COG1733	regulation of RNA biosynthetic process
EXW62_24800	COG1307	EDD domain protein, DegV family
EXW62_24810	COG1739	Uncharacterized protein family UPF0029
EXW62_24815	COG1316	TRANSCRIPTIONal
EXW62_24820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW62_24825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW62_24830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW62_24840	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW62_24840	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW62_24860	COG1486	melibiose metabolic process
EXW62_24865	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW62_24870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW62_24880	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW62_24895	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW62_24905	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW62_24910	COG1301	dicarboxylic acid transport
EXW62_24925	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW62_24930	COG1271	oxidase subunit
EXW62_24935	COG1294	oxidase, subunit
EXW62_24940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW62_24945	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW62_24950	COG1620	l-lactate permease
EXW62_24960	COG2389	metal-binding protein
EXW62_24975	COG1368	sulfuric ester hydrolase activity
EXW62_24985	COG1388	LysM domain
EXW62_24985	COG0791	NLP P60 protein
EXW62_24990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_25000	COG1215	transferase activity, transferring glycosyl groups
EXW62_25005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW62_25015	COG3584	3D domain protein
EXW62_25015	COG1388	LysM domain
EXW62_25040	COG4715	Zinc finger, swim domain protein
EXW62_25045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW62_25090	COG0577	efflux transmembrane transporter activity
EXW62_25095	COG1136	(ABC) transporter
EXW62_25120	COG5002	protein histidine kinase activity
EXW62_25120	COG3850	Histidine kinase
EXW62_25125	COG0745	RESPONSE REGULATOR receiver
EXW62_25130	COG1482	cell wall glycoprotein biosynthetic process
EXW62_25135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW62_25135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW62_25135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW62_25140	COG3711	transcriptional antiterminator
EXW62_25140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW62_25145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW62_25160	COG1482	cell wall glycoprotein biosynthetic process
EXW62_25185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW62_25190	COG2244	polysaccharide biosynthetic process
EXW62_25195	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EXW62_25200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW62_25205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW62_25210	COG4464	protein tyrosine phosphatase activity
EXW62_25215	COG0489	protein tyrosine kinase activity
EXW62_25220	COG3944	biosynthesis protein
EXW62_25225	COG0489	protein tyrosine kinase activity
EXW62_25240	COG1609	Transcriptional regulator
EXW62_25250	COG0739	heme binding
EXW62_25265	COG3279	Response regulator of the LytR AlgR family
EXW62_25270	COG2385	sporulation resulting in formation of a cellular spore
EXW62_25285	COG4836	Membrane
EXW62_25290	COG1007	ATP synthesis coupled electron transport
EXW62_25300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW62_25305	COG0713	ATP synthesis coupled electron transport
EXW62_25310	COG0839	Belongs to the complex I subunit 6 family
EXW62_25320	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW62_25325	COG0649	NAD binding
EXW62_25330	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW62_25335	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW62_25340	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW62_25345	COG5001	Diguanylate cyclase
EXW62_25345	COG3300	MHYT domain
EXW62_25360	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW62_25365	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW62_25370	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW62_25380	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW62_25385	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW62_25395	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW62_25430	COG0698	ribose 5-phosphate isomerase
EXW62_25440	COG2190	(PTS) system
EXW62_25445	COG2259	Doxx family
EXW62_25450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW62_25460	COG1971	Probably functions as a manganese efflux pump
EXW62_25465	COG0009	L-threonylcarbamoyladenylate synthase
EXW62_25480	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW62_25485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW62_25490	COG1435	thymidine kinase activity
EXW62_25500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW62_25505	COG1494	fructose-1,6-bisphosphatase
EXW62_25525	COG4821	SIS domain
EXW62_25530	COG0504	CTP synthase activity
EXW62_25535	COG3343	RNA polymerase activity
EXW62_25545	COG1960	acyl-CoA dehydrogenase activity
EXW62_25550	COG1960	acyl-CoA dehydrogenase activity
EXW62_25555	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW62_25560	COG0183	Belongs to the thiolase family
EXW62_25565	COG0247	lactate metabolic process
EXW62_25565	COG2181	nitrate reductase activity
EXW62_25570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW62_25575	COG4294	response to UV
EXW62_25580	COG5001	Diguanylate cyclase
EXW62_25580	COG3300	MHYT domain
EXW62_25595	COG3227	Zinc metalloprotease (Elastase)
EXW62_25600	COG2197	response regulator
EXW62_25605	COG4585	Histidine kinase
EXW62_25610	COG0842	Transport permease protein
EXW62_25615	COG1131	(ABC) transporter
EXW62_25620	COG0024	Methionine aminopeptidase
EXW62_25630	COG2234	aminopeptidase activity
EXW62_25645	COG4506	Protein conserved in bacteria
EXW62_25650	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW62_25675	COG2814	Major facilitator Superfamily
EXW62_25680	COG0789	Transcriptional regulator
EXW62_25685	COG0584	glycerophosphoryl diester phosphodiesterase
EXW62_25690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW62_25700	COG1994	Peptidase M50
EXW62_25710	COG1078	dGTPase activity
EXW62_25715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_25720	COG1120	ATPase activity
EXW62_25725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_25730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_25750	COG0280	phosphate acetyltransferase
EXW62_25755	COG3253	May function as heme-dependent peroxidase
EXW62_25765	COG3773	Cell wall hydrolase
EXW62_25775	COG2363	Small membrane protein
EXW62_25790	COG2233	PERMEase
EXW62_25795	COG0561	phosphatase activity
EXW62_25800	COG2814	Major facilitator Superfamily
EXW62_25805	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW62_25810	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW62_25815	COG1131	(ABC) transporter
EXW62_25820	COG2755	lipolytic protein G-D-S-L family
EXW62_25825	COG1609	Transcriptional regulator
EXW62_25835	COG0460	homoserine dehydrogenase
EXW62_25840	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW62_25845	COG2873	o-acetylhomoserine
EXW62_25860	COG2197	response regulator
EXW62_25865	COG2203	Gaf domain
EXW62_25865	COG4585	Histidine kinase
EXW62_25870	COG0351	phosphomethylpyrimidine kinase
EXW62_25875	COG3706	GGDEF domain
EXW62_25880	COG2879	small protein
EXW62_25885	COG1966	Carbon starvation protein
EXW62_25890	COG3279	Response regulator of the LytR AlgR family
EXW62_25895	COG0477	Major facilitator Superfamily
EXW62_25925	COG0840	transmembrane signaling receptor activity
EXW62_25935	COG1607	acyl-coa hydrolase
EXW62_25940	COG1216	Glycosyl transferase, family 2
EXW62_25950	COG1216	Glycosyl transferase, family 2
EXW62_25960	COG4485	Bacterial membrane protein, YfhO
EXW62_25965	COG0463	Glycosyl transferase, family 2
EXW62_25975	COG1309	transcriptional regulator
EXW62_25980	COG0488	(ABC) transporter
EXW62_25985	COG1309	transcriptional regulator
EXW62_25990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW62_25995	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW62_25995	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW62_26000	COG0628	permease
EXW62_26010	COG3279	Response regulator of the LytR AlgR family
EXW62_26015	COG3275	phosphorelay sensor kinase activity
EXW62_26025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW62_26030	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW62_26080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW62_26085	COG1272	protein, Hemolysin III
EXW62_26110	COG1164	Oligoendopeptidase f
EXW62_26125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW62_26135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW62_26140	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW62_26145	COG4853	Protein conserved in bacteria
EXW62_26155	COG5002	protein histidine kinase activity
EXW62_26160	COG0745	RESPONSE REGULATOR receiver
EXW62_26190	COG0305	Participates in initiation and elongation during chromosome replication
EXW62_26200	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW62_26205	COG4241	membrane
EXW62_26215	COG0629	single-stranded DNA binding
EXW62_26220	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW62_26225	COG0012	GTP binding
EXW62_26230	COG4481	Protein conserved in bacteria
EXW62_26235	COG0668	transmembrane transport
EXW62_26245	COG1475	DNA binding
EXW62_26250	COG1192	Involved in chromosome partitioning
EXW62_26255	COG1475	DNA binding
EXW62_26265	COG0445	tRNA wobble uridine modification
EXW62_26270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW62_26275	COG1847	R3H domain protein
EXW62_26280	COG0706	membrane insertase activity
EXW62_26285	COG0594	ribonuclease P activity
EXW62_26290	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW62_26365	COG1278	Cold shock
EXW62_26455	COG0551	DNA topoisomerase type I activity
EXW62_26455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW62_26515	COG0463	Glycosyl transferase, family 2
EXW62_26545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW62_26550	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW62_26555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW62_26560	COG0438	transferase activity, transferring glycosyl groups
EXW62_26580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW62_26585	COG0438	transferase activity, transferring glycosyl groups
EXW62_26590	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW62_26685	COG3773	Cell wall hydrolase
EXW62_26780	COG4974	Belongs to the 'phage' integrase family
EXW62_26805	COG1388	LysM domain
EXW62_26835	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW62_26855	COG0825	malonyl-CoA metabolic process
EXW62_26870	COG1846	Transcriptional regulator
EXW62_26885	COG4166	transmembrane transport
EXW62_26905	COG1192	Involved in chromosome partitioning
EXW62_26930	COG5002	protein histidine kinase activity
EXW62_27000	COG3344	reverse transcriptase
EXW62_27010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW62_27055	COG0737	Belongs to the 5'-nucleotidase family
EXW62_27160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_27220	COG0739	heme binding
EXW62_27250	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW62_27320	COG1595	DNA-templated transcription, initiation
EXW62_27325	COG1403	HNH endonuclease
EXW62_27505	COG1609	Transcriptional regulator
EXW62_27510	COG2814	Major facilitator Superfamily
EXW62_27520	COG0673	inositol 2-dehydrogenase activity
EXW62_27550	COG0191	fructose-bisphosphate aldolase activity
EXW62_27555	COG3718	enzyme involved in inositol metabolism
EXW62_27580	COG2304	oxidoreductase activity
EXW62_27605	COG1923	regulation of RNA biosynthetic process
EXW62_27620	COG1132	(ABC) transporter
EXW62_27645	COG1595	DNA-templated transcription, initiation
EXW62_27690	COG2207	Transcriptional regulator
EXW62_27735	COG2207	Transcriptional regulator
EXW62_27805	COG3338	carbonate dehydratase activity
EXW62_27815	COG5002	protein histidine kinase activity
EXW62_27845	COG4974	Belongs to the 'phage' integrase family
EXW62_27860	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW62_27870	COG0814	amino acid
EXW62_27875	COG1760	l-serine dehydratase
EXW62_27880	COG1760	l-serine dehydratase
EXW62_27895	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EXW62_27910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EXW62_27975	COG0840	transmembrane signaling receptor activity
EXW62_28000	COG0457	Tetratricopeptide repeat
EXW62_28005	COG3227	Zinc metalloprotease (Elastase)
EXW62_28070	COG1136	(ABC) transporter
EXW62_28075	COG5002	protein histidine kinase activity
EXW62_28080	COG0745	RESPONSE REGULATOR receiver
EXW62_28100	COG2378	regulation of single-species biofilm formation
EXW62_28105	COG2318	DinB family
EXW62_28115	COG4689	acetoacetate decarboxylase
EXW62_28120	COG0583	DNA-binding transcription factor activity
EXW62_28140	COG0825	malonyl-CoA metabolic process
EXW62_28175	COG1309	transcriptional regulator
EXW62_28195	COG1525	nuclease
EXW62_28250	COG4565	transcriptional regulatory protein
EXW62_28255	COG3290	protein histidine kinase activity
EXW62_28300	COG0753	catalase activity
EXW62_28410	COG0686	Belongs to the AlaDH PNT family
EXW62_28415	COG2508	Transcriptional regulator
EXW62_28415	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW62_28450	COG0083	homoserine kinase activity
EXW62_28470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW62_28480	COG2707	UPF0756 membrane protein
EXW62_28490	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW62_28505	COG2002	toxin-antitoxin pair type II binding
EXW62_28565	COG0791	NLP P60 protein
EXW62_28565	COG3883	PFAM NLP P60 protein
EXW62_28730	COG0582	viral genome integration into host DNA