locus-tag	class	description
EXW51_00005	COG1192	Involved in chromosome partitioning
EXW51_00070	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW51_00190	COG0322	excinuclease ABC activity
EXW51_00255	COG1846	Transcriptional regulator
EXW51_00290	COG0823	Involved in the tonB-independent uptake of proteins
EXW51_00360	COG0457	Tetratricopeptide repeat
EXW51_00375	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW51_00380	COG0592	DNA-directed DNA polymerase activity
EXW51_00385	COG2501	S4 domain
EXW51_00390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW51_00395	COG0187	DNA topoisomerase II activity
EXW51_00400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW51_00435	COG0516	GMP reductase activity
EXW51_00435	COG0517	IMP dehydrogenase activity
EXW51_00440	COG1686	Belongs to the peptidase S11 family
EXW51_00445	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW51_00450	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW51_00470	COG1428	Deoxynucleoside kinase
EXW51_00475	COG1428	Deoxynucleoside kinase
EXW51_00480	COG1335	isochorismatase
EXW51_00485	COG0590	tRNA wobble adenosine to inosine editing
EXW51_00495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW51_00500	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW51_00505	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW51_00550	COG1982	Orn Lys Arg decarboxylase major
EXW51_00555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW51_00560	COG0470	DNA polymerase III
EXW51_00565	COG1774	PSP1 C-terminal conserved region
EXW51_00570	COG4467	Involved in initiation control of chromosome replication
EXW51_00575	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW51_00585	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW51_00590	COG2002	toxin-antitoxin pair type II binding
EXW51_00600	COG0084	hydrolase, TatD family'
EXW51_00610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW51_00620	COG4466	Protein conserved in bacteria
EXW51_00630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW51_00635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW51_00640	COG0251	oxidation-reduction process
EXW51_00645	COG2088	sporulation resulting in formation of a cellular spore
EXW51_00650	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW51_00670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW51_00675	COG2002	toxin-antitoxin pair type II binding
EXW51_00680	COG2244	polysaccharide biosynthetic process
EXW51_00685	COG3956	TIGRFAM MazG family protein
EXW51_00690	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW51_00710	COG1098	S1 RNA binding domain
EXW51_00725	COG2208	phosphoserine phosphatase activity
EXW51_00735	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW51_00740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW51_00745	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW51_00750	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW51_00755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW51_00760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW51_00765	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW51_00770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW51_00775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW51_00780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW51_00785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW51_00790	COG1396	sequence-specific DNA binding
EXW51_00795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW51_00800	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW51_00890	COG3880	PFAM UvrB UvrC protein
EXW51_00895	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW51_00900	COG0542	response to heat
EXW51_00905	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW51_00910	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW51_00915	COG4956	integral membrane protein (PIN domain superfamily)
EXW51_00920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW51_00930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW51_00935	COG1045	serine acetyltransferase
EXW51_00940	COG0215	cysteine-tRNA ligase activity
EXW51_00950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW51_00955	COG3688	RNA-binding protein containing a PIN domain
EXW51_00965	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW51_00970	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW51_00975	COG0250	Participates in transcription elongation, termination and antitermination
EXW51_00980	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW51_00985	COG0081	regulation of translation
EXW51_00990	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW51_00995	COG0222	ribosome binding
EXW51_01000	COG2813	Specifically methylates the guanine in position
EXW51_01005	COG0085	RNA polymerase activity
EXW51_01010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW51_01015	COG1358	cellular component organization or biogenesis
EXW51_01020	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW51_01025	COG0049	tRNA binding
EXW51_01030	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW51_01035	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW51_01040	COG0051	transcription antitermination factor activity, RNA binding
EXW51_01045	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW51_01050	COG0088	Forms part of the polypeptide exit tunnel
EXW51_01055	COG0089	rRNA binding
EXW51_01060	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW51_01065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW51_01070	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW51_01080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EXW51_01085	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW51_01090	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW51_01095	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EXW51_01100	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW51_01105	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW51_01115	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW51_01125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW51_01135	COG1841	ribosomal large subunit assembly
EXW51_01140	COG0200	Binds to the 23S rRNA
EXW51_01145	COG0201	protein transport
EXW51_01150	COG0563	adenylate kinase activity
EXW51_01155	COG0024	Methionine aminopeptidase
EXW51_01165	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW51_01170	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW51_01175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW51_01200	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW51_01210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW51_01215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW51_01225	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW51_01230	COG0489	protein tyrosine kinase activity
EXW51_01240	COG2194	sulfuric ester hydrolase activity
EXW51_01245	COG0726	polysaccharide deacetylase
EXW51_01325	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW51_01330	COG4856	YbbR-like protein
EXW51_01335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW51_01365	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_01370	COG2011	ABC-type metal ion transport system permease component
EXW51_01380	COG1464	Belongs to the NlpA lipoprotein family
EXW51_01395	COG0277	FAD linked oxidase domain protein
EXW51_01400	COG2271	Major facilitator Superfamily
EXW51_01410	COG2814	Major facilitator Superfamily
EXW51_01430	COG0601	transmembrane transport
EXW51_01435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW51_01440	COG0444	Belongs to the ABC transporter superfamily
EXW51_01445	COG4608	Belongs to the ABC transporter superfamily
EXW51_01450	COG4166	transmembrane transport
EXW51_01460	COG2207	Transcriptional regulator
EXW51_01475	COG4166	transmembrane transport
EXW51_01480	COG4166	transmembrane transport
EXW51_01485	COG0656	L-ascorbic acid biosynthetic process
EXW51_01490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW51_01505	COG4149	molybdate abc transporter
EXW51_01510	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW51_01515	COG1910	domain protein
EXW51_01530	COG0697	spore germination
EXW51_01545	COG0204	Acyl-transferase
EXW51_01555	COG1609	Transcriptional regulator
EXW51_01565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW51_01580	COG5298	Protein conserved in bacteria
EXW51_01605	COG0488	(ABC) transporter
EXW51_01610	COG4585	Histidine kinase
EXW51_01615	COG2197	response regulator
EXW51_01620	COG1131	(ABC) transporter
EXW51_01625	COG0842	Transport permease protein
EXW51_01625	COG1511	domain protein
EXW51_01630	COG0842	Transport permease protein
EXW51_01640	COG0747	negative chemotaxis
EXW51_01650	COG0601	transmembrane transport
EXW51_01655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW51_01660	COG0444	Belongs to the ABC transporter superfamily
EXW51_01665	COG4608	Belongs to the ABC transporter superfamily
EXW51_01675	COG0561	phosphatase activity
EXW51_01705	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW51_01710	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW51_01720	COG0531	amino acid
EXW51_01725	COG2814	Major facilitator Superfamily
EXW51_01735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW51_01745	COG4294	response to UV
EXW51_01750	COG0705	Rhomboid family
EXW51_01755	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW51_01760	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW51_01765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW51_01770	COG0864	Transcriptional regulator
EXW51_01775	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW51_01780	COG2183	response to ionizing radiation
EXW51_01880	COG0802	atpase or kinase
EXW51_01885	COG1214	PFAM Peptidase M22, glycoprotease
EXW51_01890	COG0456	acetyltransferase
EXW51_01900	COG0488	(ABC) transporter
EXW51_01905	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW51_01915	COG1266	CAAX protease self-immunity
EXW51_01920	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW51_01925	COG0459	protein refolding
EXW51_01930	COG0519	Catalyzes the synthesis of GMP from XMP
EXW51_01930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW51_01935	COG2252	PERMEase
EXW51_01945	COG5002	protein histidine kinase activity
EXW51_01965	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW51_01985	COG0693	protein deglycase activity
EXW51_02025	COG4187	Peptidase family M20/M25/M40
EXW51_02085	COG0697	spore germination
EXW51_02120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW51_02125	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW51_02130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW51_02135	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW51_02140	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW51_02145	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW51_02150	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW51_02155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW51_02165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW51_02170	COG0138	bifunctional purine biosynthesis protein purh
EXW51_02175	COG0151	Belongs to the GarS family
EXW51_02195	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW51_02200	COG0210	DNA helicase
EXW51_02205	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW51_02210	COG4851	CamS sex pheromone cAM373 precursor
EXW51_02220	COG1012	belongs to the aldehyde dehydrogenase family
EXW51_02225	COG1335	isochorismatase
EXW51_02235	COG2011	ABC-type metal ion transport system permease component
EXW51_02240	COG1464	Belongs to the NlpA lipoprotein family
EXW51_02255	COG0003	Pfam Anion-transporting ATPase
EXW51_02260	COG1846	Transcriptional regulator
EXW51_02265	COG4682	membrane
EXW51_02285	COG1597	lipid kinase activity
EXW51_02300	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW51_02315	COG1012	belongs to the aldehyde dehydrogenase family
EXW51_02320	COG2076	Multidrug Resistance protein
EXW51_02330	COG2309	aminopeptidase activity
EXW51_02345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW51_02355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW51_02360	COG5002	protein histidine kinase activity
EXW51_02365	COG4807	Protein conserved in bacteria
EXW51_02390	COG1757	Na H antiporter
EXW51_02395	COG1473	amidohydrolase
EXW51_02410	COG0450	alkyl hydroperoxide reductase
EXW51_02420	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW51_02430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW51_02435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW51_02440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW51_02450	COG0492	ferredoxin-NADP+ reductase activity
EXW51_02465	COG0166	Belongs to the GPI family
EXW51_02490	COG5002	protein histidine kinase activity
EXW51_02510	COG3541	Predicted nucleotidyltransferase
EXW51_02515	COG2814	Major facilitator Superfamily
EXW51_02520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW51_02520	COG0723	plastoquinol--plastocyanin reductase activity
EXW51_02530	COG0765	amino acid transport
EXW51_02535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW51_02545	COG0840	transmembrane signaling receptor activity
EXW51_02570	COG0549	Belongs to the carbamate kinase family
EXW51_02585	COG0277	FAD linked oxidase domain protein
EXW51_02590	COG0366	Alpha amylase catalytic
EXW51_02595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW51_02595	COG1263	PTS System
EXW51_02595	COG2190	(PTS) system
EXW51_02615	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW51_02620	COG0352	thiamine-phosphate diphosphorylase activity
EXW51_02625	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW51_02645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW51_02650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW51_02655	COG1116	anion transmembrane transporter activity
EXW51_02660	COG0488	(ABC) transporter
EXW51_02705	COG2270	Major facilitator Superfamily
EXW51_02735	COG2310	stress, protein
EXW51_02740	COG2310	stress, protein
EXW51_02745	COG2310	stress, protein
EXW51_02750	COG0861	Integral membrane protein TerC family
EXW51_02760	COG3853	Toxic anion resistance protein (TelA)
EXW51_02770	COG4840	Belongs to the UPF0435 family
EXW51_02775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW51_02785	COG1295	ribonuclease BN
EXW51_02790	COG2217	Heavy metal translocating P-type atpase
EXW51_02795	COG0697	spore germination
EXW51_02815	COG0586	Pfam SNARE associated Golgi protein
EXW51_02830	COG3871	stress protein (general stress protein 26)
EXW51_02835	COG0387	Pfam Sodium calcium exchanger
EXW51_02845	COG0535	radical SAM domain protein
EXW51_02865	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW51_02885	COG3829	transcription factor binding
EXW51_02895	COG0833	amino acid
EXW51_02900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW51_02930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW51_02930	COG1263	PTS System
EXW51_02935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW51_02950	COG1216	Glycosyl transferase, family 2
EXW51_02960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW51_02960	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW51_02965	COG0463	Glycosyl transferase, family 2
EXW51_02980	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW51_02985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW51_03000	COG1228	amidohydrolase
EXW51_03005	COG1090	epimerase
EXW51_03010	COG2137	regulation of response to DNA damage stimulus
EXW51_03035	COG1988	membrane-bound metal-dependent
EXW51_03040	COG1194	a g-specific adenine glycosylase
EXW51_03060	COG3557	Belongs to the UPF0374 family
EXW51_03065	COG1132	(ABC) transporter
EXW51_03070	COG4129	membrane
EXW51_03080	COG0069	glutamate synthase activity
EXW51_03080	COG0067	glutamate synthase
EXW51_03080	COG0070	glutamate synthase
EXW51_03085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW51_03090	COG4555	ABC transporter
EXW51_03110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW51_03115	COG0735	belongs to the Fur family
EXW51_03235	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW51_03240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW51_03260	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW51_03270	COG2766	serine protein kinase
EXW51_03275	COG2718	Belongs to the UPF0229 family
EXW51_03290	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW51_03295	COG2268	Band 7 protein
EXW51_03305	COG3290	protein histidine kinase activity
EXW51_03310	COG4565	transcriptional regulatory protein
EXW51_03315	COG2851	Citrate transporter
EXW51_03340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW51_03345	COG0745	RESPONSE REGULATOR receiver
EXW51_03350	COG5002	protein histidine kinase activity
EXW51_03360	COG4990	cell redox homeostasis
EXW51_03370	COG3290	protein histidine kinase activity
EXW51_03375	COG4565	transcriptional regulatory protein
EXW51_03380	COG3493	citrate carrier protein
EXW51_03385	COG0281	malic enzyme
EXW51_03395	COG0697	spore germination
EXW51_03400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW51_03410	COG5002	protein histidine kinase activity
EXW51_03415	COG0745	RESPONSE REGULATOR receiver
EXW51_03420	COG0456	acetyltransferase
EXW51_03425	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW51_03430	COG3383	formate dehydrogenase (NAD+) activity
EXW51_03435	COG2427	Protein of unknown function (DUF1641)
EXW51_03450	COG0531	amino acid
EXW51_03460	COG0640	Transcriptional regulator
EXW51_03465	COG2217	Heavy metal translocating P-type atpase
EXW51_03470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW51_03480	COG3227	Zinc metalloprotease (Elastase)
EXW51_03500	COG2720	vancomycin resistance protein
EXW51_03505	COG1316	TRANSCRIPTIONal
EXW51_03510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW51_03515	COG0346	lactoylglutathione lyase activity
EXW51_03520	COG1253	flavin adenine dinucleotide binding
EXW51_03525	COG1027	Aspartate ammonia-lyase
EXW51_03530	COG1620	l-lactate permease
EXW51_03535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW51_03555	COG3104	oligopeptide transport
EXW51_03560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW51_03565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW51_03570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW51_03585	COG0156	8-amino-7-oxononanoate synthase activity
EXW51_03590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW51_03600	COG4548	von Willebrand factor, type A
EXW51_03605	COG0714	Associated with various cellular activities
EXW51_03630	COG0531	amino acid
EXW51_03635	COG2188	Transcriptional regulator
EXW51_03640	COG1263	PTS System
EXW51_03640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW51_03645	COG0366	Alpha amylase catalytic
EXW51_03660	COG0697	spore germination
EXW51_03670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW51_03675	COG1115	amino acid carrier protein
EXW51_03680	COG1126	abc transporter atp-binding protein
EXW51_03685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW51_03690	COG0765	amino acid transport
EXW51_03695	COG0765	amino acid transport
EXW51_03700	COG0833	amino acid
EXW51_03730	COG2378	regulation of single-species biofilm formation
EXW51_03735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW51_03740	COG5002	protein histidine kinase activity
EXW51_03755	COG0659	secondary active sulfate transmembrane transporter activity
EXW51_03770	COG2271	Major facilitator Superfamily
EXW51_03775	COG1846	Transcriptional regulator
EXW51_03780	COG0477	Major facilitator Superfamily
EXW51_03785	COG1609	Transcriptional regulator
EXW51_03790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW51_03795	COG1869	D-ribose catabolic process
EXW51_03805	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW51_03810	COG1879	ABC-type sugar transport system periplasmic component
EXW51_03830	COG1063	alcohol dehydrogenase
EXW51_03875	COG0840	transmembrane signaling receptor activity
EXW51_03880	COG3584	3D domain protein
EXW51_03880	COG1388	LysM domain
EXW51_03885	COG1476	TRANSCRIPTIONal
EXW51_03905	COG3104	oligopeptide transport
EXW51_03910	COG1114	Component of the transport system for branched-chain amino acids
EXW51_03925	COG1113	amino acid transport
EXW51_03930	COG2252	PERMEase
EXW51_03945	COG2153	protein acetylation
EXW51_03955	COG0569	domain protein
EXW51_03955	COG0475	glutathione-regulated potassium exporter activity
EXW51_03965	COG1845	cytochrome c oxidase, subunit III
EXW51_03970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW51_03980	COG0833	amino acid
EXW51_03985	COG4990	cell redox homeostasis
EXW51_04000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW51_04005	COG0697	spore germination
EXW51_04010	COG0531	amino acid
EXW51_04020	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW51_04025	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW51_04035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW51_04040	COG0573	inorganic phosphate transmembrane transporter activity
EXW51_04045	COG0581	inorganic phosphate transmembrane transporter activity
EXW51_04055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW51_04175	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW51_04190	COG3103	Sh3 type 3 domain protein
EXW51_04190	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW51_04190	COG4991	sh3 domain protein
EXW51_04195	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW51_04200	COG1116	anion transmembrane transporter activity
EXW51_04205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW51_04210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW51_04215	COG0352	thiamine-phosphate diphosphorylase activity
EXW51_04220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW51_04225	COG2104	thiamine diphosphate biosynthetic process
EXW51_04235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW51_04240	COG0351	phosphomethylpyrimidine kinase
EXW51_04265	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW51_04270	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW51_04275	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW51_04280	COG2205	protein histidine kinase activity
EXW51_04285	COG2814	Major facilitator Superfamily
EXW51_04290	COG1846	Transcriptional regulator
EXW51_04310	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW51_04315	COG1129	ABC transporter
EXW51_04320	COG1879	ABC-type sugar transport system periplasmic component
EXW51_04325	COG2252	PERMEase
EXW51_04330	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_04390	COG0778	Nitroreductase
EXW51_04395	COG2719	SpoVR family
EXW51_04415	COG3591	Belongs to the peptidase S1B family
EXW51_04425	COG1937	Protein conserved in bacteria
EXW51_04430	COG0425	Belongs to the sulfur carrier protein TusA family
EXW51_04430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW51_04435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW51_04435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW51_04440	COG0425	Belongs to the sulfur carrier protein TusA family
EXW51_04445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW51_04445	COG0425	Belongs to the sulfur carrier protein TusA family
EXW51_04450	COG2210	Belongs to the sulfur carrier protein TusA family
EXW51_04455	COG0730	response to heat
EXW51_04465	COG1316	TRANSCRIPTIONal
EXW51_04470	COG0604	alcohol dehydrogenase
EXW51_04475	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW51_04480	COG0604	alcohol dehydrogenase
EXW51_04500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW51_04500	COG3711	transcriptional antiterminator
EXW51_04505	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW51_04510	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW51_04530	COG1388	LysM domain
EXW51_04530	COG3584	3D domain protein
EXW51_04535	COG0577	efflux transmembrane transporter activity
EXW51_04540	COG1136	(ABC) transporter
EXW51_04550	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW51_04565	COG0577	efflux transmembrane transporter activity
EXW51_04570	COG1114	Component of the transport system for branched-chain amino acids
EXW51_04575	COG3546	catalase activity
EXW51_04600	COG0586	Pfam SNARE associated Golgi protein
EXW51_04630	COG0531	amino acid
EXW51_04635	COG0475	glutathione-regulated potassium exporter activity
EXW51_04645	COG1737	Transcriptional regulator
EXW51_04655	COG1263	PTS System
EXW51_04655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW51_04665	COG2259	Doxx family
EXW51_04690	COG1522	sequence-specific DNA binding
EXW51_04715	COG2076	Multidrug Resistance protein
EXW51_04720	COG1309	transcriptional regulator
EXW51_04730	COG2814	Major facilitator Superfamily
EXW51_04735	COG1733	regulation of RNA biosynthetic process
EXW51_04755	COG4533	DNA binding
EXW51_04760	COG2211	Major facilitator Superfamily
EXW51_04775	COG0531	amino acid
EXW51_04780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EXW51_04785	COG1012	belongs to the aldehyde dehydrogenase family
EXW51_04800	COG1132	(ABC) transporter
EXW51_04805	COG1132	(ABC) transporter
EXW51_04810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW51_04815	COG0765	amino acid transport
EXW51_04820	COG1126	abc transporter atp-binding protein
EXW51_04835	COG0189	ligase activity
EXW51_04845	COG4399	Belongs to the UPF0754 family
EXW51_04850	COG3679	Belongs to the UPF0342 family
EXW51_04855	COG0028	Belongs to the TPP enzyme family
EXW51_04860	COG3527	Alpha-acetolactate decarboxylase
EXW51_04865	COG0463	Glycosyl transferase, family 2
EXW51_04870	COG1216	Glycosyl transferase, family 2
EXW51_04875	COG2094	Belongs to the DNA glycosylase MPG family
EXW51_04880	COG0561	phosphatase activity
EXW51_04890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW51_04895	COG0318	PFAM AMP-dependent synthetase and ligase
EXW51_04905	COG0659	secondary active sulfate transmembrane transporter activity
EXW51_04925	COG2244	polysaccharide biosynthetic process
EXW51_04960	COG1696	Membrane protein involved in D-alanine export
EXW51_04975	COG1024	Enoyl-CoA hydratase
EXW51_04990	COG1363	Peptidase, m42
EXW51_05005	COG2318	DinB family
EXW51_05025	COG0579	oxidoreductase
EXW51_05050	COG0601	transmembrane transport
EXW51_05055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW51_05060	COG0444	Belongs to the ABC transporter superfamily
EXW51_05065	COG4608	Belongs to the ABC transporter superfamily
EXW51_05070	COG0322	excinuclease ABC activity
EXW51_05190	COG0477	Major facilitator Superfamily
EXW51_05195	COG3290	protein histidine kinase activity
EXW51_05200	COG4565	transcriptional regulatory protein
EXW51_05205	COG3181	Tripartite tricarboxylate transporter family receptor
EXW51_05220	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EXW51_05250	COG0789	Transcriptional regulator
EXW51_05250	COG4978	Transcriptional regulator
EXW51_05275	COG0305	Participates in initiation and elongation during chromosome replication
EXW51_05310	COG1842	Phage shock protein A
EXW51_05320	COG0477	Major facilitator Superfamily
EXW51_05410	COG2814	Major facilitator Superfamily
EXW51_05415	COG0640	Transcriptional regulator
EXW51_05445	COG2376	Dihydroxyacetone kinase
EXW51_05460	COG2376	Dihydroxyacetone kinase
EXW51_05495	COG0076	glutamate decarboxylase activity
EXW51_05560	COG2807	transmembrane transport
EXW51_05590	COG4585	Histidine kinase
EXW51_05595	COG2197	response regulator
EXW51_05625	COG0420	3'-5' exonuclease activity
EXW51_05630	COG4717	serine-type aminopeptidase activity
EXW51_05635	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW51_05645	COG0346	lactoylglutathione lyase activity
EXW51_05650	COG0346	lactoylglutathione lyase activity
EXW51_05655	COG0457	Tetratricopeptide repeat
EXW51_05665	COG2267	carboxylic ester hydrolase activity
EXW51_05680	COG3620	sequence-specific DNA binding
EXW51_05685	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW51_05690	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW51_05695	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW51_05700	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW51_05705	COG1595	DNA-templated transcription, initiation
EXW51_05720	COG3973	AAA domain
EXW51_05730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW51_05755	COG0537	adenosine 5'-monophosphoramidase activity
EXW51_05760	COG1131	(ABC) transporter
EXW51_05765	COG4473	ABC transporter
EXW51_05775	COG0247	lactate metabolic process
EXW51_05780	COG1139	Iron-sulfur cluster binding protein
EXW51_05785	COG1556	Lactate utilization protein
EXW51_05795	COG1309	transcriptional regulator
EXW51_05800	COG3402	PFAM membrane-flanked domain
EXW51_05805	COG3428	Bacterial PH domain
EXW51_05845	COG3402	PFAM membrane-flanked domain
EXW51_05850	COG3428	Bacterial PH domain
EXW51_05855	COG2329	Antibiotic biosynthesis monooxygenase
EXW51_05860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW51_05865	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW51_05870	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW51_05875	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW51_05905	COG1309	transcriptional regulator
EXW51_05910	COG1511	domain protein
EXW51_05945	COG2378	regulation of single-species biofilm formation
EXW51_05950	COG1609	Transcriptional regulator
EXW51_05960	COG1234	tRNA 3'-trailer cleavage
EXW51_05965	COG0095	Lipoate-protein ligase
EXW51_05975	COG0318	PFAM AMP-dependent synthetase and ligase
EXW51_05990	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW51_05995	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW51_06000	COG4208	sulfate ABC transporter
EXW51_06030	COG1408	metallophosphoesterase
EXW51_06035	COG1078	dGTPase activity
EXW51_06050	COG1595	DNA-templated transcription, initiation
EXW51_06060	COG2207	Transcriptional regulator
EXW51_06060	COG3708	Transcriptional regulator
EXW51_06065	COG2205	protein histidine kinase activity
EXW51_06070	COG0745	RESPONSE REGULATOR receiver
EXW51_06090	COG0501	Belongs to the peptidase M48B family
EXW51_06095	COG0840	transmembrane signaling receptor activity
EXW51_06100	COG0697	spore germination
EXW51_06130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW51_06135	COG2224	Isocitrate lyase
EXW51_06145	COG1278	Cold shock
EXW51_06155	COG4903	ComK protein
EXW51_06165	COG0398	Pfam SNARE associated Golgi protein
EXW51_06175	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW51_06180	COG1074	ATP-dependent DNA helicase activity
EXW51_06230	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW51_06255	COG0367	asparagine synthase
EXW51_06265	COG0753	catalase activity
EXW51_06270	COG0004	ammonium transporteR
EXW51_06280	COG1666	GTP binding
EXW51_06285	COG2996	Protein conserved in bacteria
EXW51_06290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW51_06300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW51_06315	COG0561	phosphatase activity
EXW51_06335	COG2267	carboxylic ester hydrolase activity
EXW51_06350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW51_06355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW51_06360	COG5504	Zn-dependent protease
EXW51_06375	COG0180	Tryptophanyl-tRNA synthetase
EXW51_06390	COG4166	transmembrane transport
EXW51_06395	COG0601	transmembrane transport
EXW51_06400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW51_06405	COG0444	Belongs to the ABC transporter superfamily
EXW51_06410	COG4608	Belongs to the ABC transporter superfamily
EXW51_06415	COG0534	Mate efflux family protein
EXW51_06420	COG4166	transmembrane transport
EXW51_06440	COG0861	Integral membrane protein TerC family
EXW51_06445	COG4862	establishment of competence for transformation
EXW51_06450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW51_06460	COG1164	Oligoendopeptidase f
EXW51_06470	COG2346	COG2346, Truncated hemoglobins
EXW51_06475	COG4116	CYTH
EXW51_06485	COG2357	RelA SpoT domain protein
EXW51_06495	COG0564	pseudouridine synthase activity
EXW51_06505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW51_06515	COG1216	Glycosyl transferase, family 2
EXW51_06535	COG0457	Tetratricopeptide repeat
EXW51_06535	COG0463	Glycosyl transferase, family 2
EXW51_06555	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW51_06570	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW51_06615	COG2153	protein acetylation
EXW51_06620	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW51_06625	COG2382	esterase
EXW51_06650	COG5492	domain, Protein
EXW51_06655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW51_06670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW51_06670	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW51_06675	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW51_06680	COG0134	indole-3-glycerol-phosphate synthase activity
EXW51_06685	COG0135	phosphoribosylanthranilate isomerase activity
EXW51_06690	COG0133	tryptophan synthase activity
EXW51_06695	COG0159	tryptophan synthase activity
EXW51_06705	COG1620	l-lactate permease
EXW51_06710	COG5634	Uncharacterized conserved protein (DUF2278)
EXW51_06745	COG2226	methyltransferase
EXW51_06765	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW51_06770	COG0567	Dehydrogenase, E1 component
EXW51_06800	COG4152	abc transporter atp-binding protein
EXW51_06805	COG1668	transmembrane transport
EXW51_06825	COG1686	Belongs to the peptidase S11 family
EXW51_06830	COG0681	Belongs to the peptidase S26 family
EXW51_06865	COG1012	belongs to the aldehyde dehydrogenase family
EXW51_06875	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW51_06880	COG1177	transmembrane transport
EXW51_06885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW51_06895	COG2409	Drug exporters of the RND superfamily
EXW51_06905	COG0564	pseudouridine synthase activity
EXW51_06915	COG2340	Cysteine-rich secretory protein family
EXW51_06920	COG0247	lactate metabolic process
EXW51_06925	COG0277	FAD linked oxidase domain protein
EXW51_06930	COG3835	regulator
EXW51_06940	COG0745	RESPONSE REGULATOR receiver
EXW51_06945	COG5002	protein histidine kinase activity
EXW51_06950	COG2186	Transcriptional regulator
EXW51_06955	COG0247	lactate metabolic process
EXW51_06960	COG1139	Iron-sulfur cluster binding protein
EXW51_06965	COG1556	Lactate utilization protein
EXW51_06970	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW51_06980	COG2116	formate transmembrane transporter activity
EXW51_06985	COG0861	Integral membrane protein TerC family
EXW51_06990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW51_07000	COG2030	dehydratase
EXW51_07020	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_07025	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW51_07035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW51_07050	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW51_07055	COG3842	ATPase activity
EXW51_07065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW51_07070	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW51_07080	COG1349	DNA-binding transcription factor activity
EXW51_07090	COG0235	Class ii aldolase
EXW51_07100	COG2861	carbohydrate metabolic process
EXW51_07110	COG3852	Histidine kinase
EXW51_07115	COG1846	Transcriptional regulator
EXW51_07125	COG2318	DinB family
EXW51_07130	COG5002	protein histidine kinase activity
EXW51_07135	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW51_07140	COG0720	synthase
EXW51_07150	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW51_07155	COG4873	Protein conserved in bacteria
EXW51_07165	COG0456	acetyltransferase
EXW51_07185	COG1780	Probably involved in ribonucleotide reductase function
EXW51_07200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW51_07205	COG0531	amino acid
EXW51_07220	COG3829	transcription factor binding
EXW51_07220	COG3290	protein histidine kinase activity
EXW51_07225	COG1012	belongs to the aldehyde dehydrogenase family
EXW51_07235	COG1725	Transcriptional regulator
EXW51_07240	COG1131	(ABC) transporter
EXW51_07250	COG1131	(ABC) transporter
EXW51_07255	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW51_07260	COG1266	CAAX protease self-immunity
EXW51_07270	COG1522	sequence-specific DNA binding
EXW51_07280	COG1335	isochorismatase
EXW51_07290	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW51_07295	COG2070	2-Nitropropane dioxygenase
EXW51_07300	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW51_07305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW51_07310	COG1696	Membrane protein involved in D-alanine export
EXW51_07315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW51_07330	COG0716	FMN binding
EXW51_07355	COG0534	Mate efflux family protein
EXW51_07380	COG1846	Transcriptional regulator
EXW51_07395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW51_07405	COG3874	Sporulation protein YtfJ
EXW51_07430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW51_07435	COG0028	Belongs to the TPP enzyme family
EXW51_07440	COG0440	acetolactate synthase activity
EXW51_07450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW51_07460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW51_07470	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW51_07475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW51_07485	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW51_07490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW51_07495	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW51_07500	COG0107	imidazoleglycerol-phosphate synthase activity
EXW51_07510	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW51_07515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW51_07530	COG1183	phosphatidylcholine synthase activity
EXW51_07535	COG1368	sulfuric ester hydrolase activity
EXW51_07545	COG0019	diaminopimelate decarboxylase activity
EXW51_07555	COG0175	sulfate reduction
EXW51_07560	COG2046	Belongs to the sulfate adenylyltransferase family
EXW51_07565	COG0529	Catalyzes the synthesis of activated sulfate
EXW51_07570	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW51_07590	COG1648	precorrin-2 dehydrogenase activity
EXW51_07595	COG0733	neurotransmitter:sodium symporter activity
EXW51_07620	COG1757	Na H antiporter
EXW51_07640	COG4758	membrane
EXW51_07645	COG4585	Histidine kinase
EXW51_07650	COG2197	response regulator
EXW51_07660	COG1114	Component of the transport system for branched-chain amino acids
EXW51_07670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW51_07715	COG0730	response to heat
EXW51_07720	COG0306	phosphate transporter
EXW51_07725	COG1392	Phosphate transport regulator
EXW51_07730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW51_07745	COG3852	Histidine kinase
EXW51_07750	COG1801	Protein of unknown function DUF72
EXW51_07760	COG0582	viral genome integration into host DNA
EXW51_07765	COG5002	protein histidine kinase activity
EXW51_07780	COG0392	lysyltransferase activity
EXW51_07780	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW51_07795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW51_07800	COG1686	Belongs to the peptidase S11 family
EXW51_07805	COG2715	membrane protein required for spore maturation
EXW51_07810	COG0700	Nucleoside recognition
EXW51_07815	COG1187	pseudouridine synthase activity
EXW51_07825	COG1333	cytochrome c biogenesis protein
EXW51_07830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW51_07835	COG0745	RESPONSE REGULATOR receiver
EXW51_07840	COG5002	protein histidine kinase activity
EXW51_07845	COG2096	Adenosyltransferase
EXW51_07850	COG4942	peptidase
EXW51_07860	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW51_07865	COG1141	Ferredoxin
EXW51_07875	COG4955	Helix-turn-helix domain
EXW51_07880	COG0514	ATP-dependent DNA helicase (RecQ)
EXW51_07885	COG1266	CAAX protease self-immunity
EXW51_07895	COG1408	metallophosphoesterase
EXW51_07910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW51_07930	COG0492	ferredoxin-NADP+ reductase activity
EXW51_07935	COG0252	asparaginase activity
EXW51_07940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW51_07950	COG1304	FMN binding
EXW51_07980	COG1160	GTP binding
EXW51_07985	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW51_08005	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW51_08015	COG0302	gtp cyclohydrolase
EXW51_08020	COG0142	geranyltranstransferase activity
EXW51_08025	COG2226	methyltransferase
EXW51_08030	COG0142	geranyltranstransferase activity
EXW51_08045	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW51_08055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW51_08060	COG0457	Tetratricopeptide repeat
EXW51_08065	COG5582	Belongs to the UPF0302 family
EXW51_08080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW51_08095	COG4347	Protein of unknown function (DUF1405)
EXW51_08110	COG2738	Putative neutral zinc metallopeptidase
EXW51_08120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW51_08130	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW51_08135	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW51_08140	COG1803	Methylglyoxal synthase
EXW51_08145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW51_08150	COG0438	transferase activity, transferring glycosyl groups
EXW51_08155	COG0617	tRNA 3'-terminal CCA addition
EXW51_08165	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW51_08170	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW51_08180	COG1199	ATP-dependent helicase activity
EXW51_08180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW51_08200	COG3935	DnaD domain protein
EXW51_08205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW51_08215	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW51_08215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW51_08220	COG3331	DNA recombination
EXW51_08255	COG4474	Belongs to the UPF0398 family
EXW51_08260	COG3599	regulation of cell shape
EXW51_08270	COG0116	Belongs to the methyltransferase superfamily
EXW51_08280	COG1199	ATP-dependent helicase activity
EXW51_08285	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW51_08295	COG0024	Methionine aminopeptidase
EXW51_08305	COG2233	PERMEase
EXW51_08310	COG2311	Membrane
EXW51_08315	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW51_08325	COG0456	acetyltransferase
EXW51_08335	COG2897	thiosulfate sulfurtransferase activity
EXW51_08375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW51_08390	COG0454	-acetyltransferase
EXW51_08410	COG0328	RNA-DNA hybrid ribonuclease activity
EXW51_08445	COG3403	YqcI/YcgG family
EXW51_08450	COG1280	lysine exporter protein (LysE YggA)
EXW51_08465	COG3162	membrane
EXW51_08470	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW51_08475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW51_08485	COG0475	glutathione-regulated potassium exporter activity
EXW51_08490	COG0789	Transcriptional regulator
EXW51_08490	COG4978	Transcriptional regulator
EXW51_08500	COG2323	membrane
EXW51_08505	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW51_08550	COG2814	Major facilitator Superfamily
EXW51_08570	COG1923	regulation of RNA biosynthetic process
EXW51_08580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW51_08585	COG1360	Flagellar Motor Protein
EXW51_08590	COG2201	protein-glutamate methylesterase activity
EXW51_08595	COG2198	Histidine kinase
EXW51_08595	COG0643	Histidine kinase
EXW51_08600	COG1776	CheC inhibitor of MCP methylation
EXW51_08600	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW51_08620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW51_08640	COG1256	bacterial-type flagellum assembly
EXW51_08645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW51_08665	COG1815	bacterial-type flagellum-dependent cell motility
EXW51_08670	COG1558	bacterial-type flagellum-dependent cell motility
EXW51_08680	COG1766	The M ring may be actively involved in energy transduction
EXW51_08685	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW51_08695	COG1157	protein secretion by the type III secretion system
EXW51_08730	COG0835	chemotaxis
EXW51_08730	COG0784	Response regulator, receiver
EXW51_08755	COG0861	Integral membrane protein TerC family
EXW51_08765	COG3383	formate dehydrogenase (NAD+) activity
EXW51_08770	COG2427	Protein of unknown function (DUF1641)
EXW51_08775	COG5609	conserved protein (DUF2294)
EXW51_08780	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW51_08790	COG2116	formate transmembrane transporter activity
EXW51_08795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW51_08800	COG0303	'Molybdopterin
EXW51_08805	COG0314	molybdopterin synthase activity
EXW51_08810	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW51_08820	COG0489	protein tyrosine kinase activity
EXW51_08825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW51_08870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW51_08875	COG0741	lytic transglycosylase activity
EXW51_08885	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW51_08890	COG1776	CheC inhibitor of MCP methylation
EXW51_08890	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW51_08900	COG1338	Plays a role in the flagellum-specific transport system
EXW51_08905	COG1987	bacterial-type flagellum assembly
EXW51_08915	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW51_08920	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW51_08925	COG1419	protein localization to endoplasmic reticulum
EXW51_08930	COG4786	Flagellar basal body rod
EXW51_08975	COG0412	Dienelactone hydrolase
EXW51_08980	COG2329	Antibiotic biosynthesis monooxygenase
EXW51_09005	COG0583	DNA-binding transcription factor activity
EXW51_09010	COG3842	ATPase activity
EXW51_09055	COG1686	Belongs to the peptidase S11 family
EXW51_09090	COG0367	asparagine synthase
EXW51_09120	COG1802	Transcriptional regulator
EXW51_09125	COG0697	spore germination
EXW51_09140	COG0438	transferase activity, transferring glycosyl groups
EXW51_09140	COG1216	Glycosyl transferase, family 2
EXW51_09145	COG1757	Na H antiporter
EXW51_09175	COG0534	Mate efflux family protein
EXW51_09180	COG3340	Belongs to the peptidase S51 family
EXW51_09200	COG0785	Cytochrome C biogenesis protein
EXW51_09205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW51_09220	COG3048	D-serine ammonia-lyase activity
EXW51_09225	COG2733	membrane
EXW51_09265	COG1131	(ABC) transporter
EXW51_09285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW51_09300	COG0528	UMP kinase activity
EXW51_09310	COG1027	Aspartate ammonia-lyase
EXW51_09315	COG0281	malic enzyme
EXW51_09320	COG4191	Histidine kinase
EXW51_09325	COG0784	Response regulator, receiver
EXW51_09330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW51_09345	COG2502	aspartate--ammonia ligase
EXW51_09350	COG3620	sequence-specific DNA binding
EXW51_09410	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW51_09420	COG2814	Major facilitator Superfamily
EXW51_09445	COG1695	Transcriptional regulator
EXW51_09460	COG0477	Major facilitator Superfamily
EXW51_09465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW51_09475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW51_09480	COG2223	nitrite transmembrane transporter activity
EXW51_09485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW51_09500	COG2244	polysaccharide biosynthetic process
EXW51_09505	COG0733	neurotransmitter:sodium symporter activity
EXW51_09515	COG5566	PFAM Mor transcription activator
EXW51_09520	COG2323	membrane
EXW51_09545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW51_09550	COG2132	Multicopper oxidase
EXW51_09560	COG5002	protein histidine kinase activity
EXW51_09565	COG0745	RESPONSE REGULATOR receiver
EXW51_09580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW51_09605	COG2814	Major facilitator Superfamily
EXW51_09610	COG3384	dioxygenase
EXW51_09660	COG4166	transmembrane transport
EXW51_09665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW51_09685	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW51_09690	COG1054	Belongs to the UPF0176 family
EXW51_09700	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW51_09705	COG0531	amino acid
EXW51_09725	COG1280	lysine exporter protein (LysE YggA)
EXW51_09755	COG5002	protein histidine kinase activity
EXW51_09760	COG1136	(ABC) transporter
EXW51_09775	COG2390	Transcriptional regulator
EXW51_09780	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW51_09785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW51_09790	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW51_09805	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW51_09815	COG2267	carboxylic ester hydrolase activity
EXW51_09820	COG0583	DNA-binding transcription factor activity
EXW51_09835	COG0006	proline dipeptidase activity
EXW51_09840	COG2132	Multicopper oxidase
EXW51_09855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW51_09875	COG1114	Component of the transport system for branched-chain amino acids
EXW51_09885	COG4641	Protein conserved in bacteria
EXW51_09895	COG1276	copper resistance
EXW51_09895	COG2372	response to copper ion
EXW51_09900	COG4549	nuclear export factor GLE1
EXW51_09910	COG0697	spore germination
EXW51_09915	COG0583	DNA-binding transcription factor activity
EXW51_09920	COG1959	2 iron, 2 sulfur cluster binding
EXW51_09925	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW51_09930	COG0778	Nitroreductase
EXW51_09945	COG0628	permease
EXW51_09960	COG1231	oxidoreductase activity
EXW51_09965	COG0523	cobalamin synthesis protein
EXW51_09975	COG0411	ABC transporter
EXW51_09995	COG0583	DNA-binding transcription factor activity
EXW51_10005	COG1942	4-Oxalocrotonate Tautomerase
EXW51_10020	COG0346	lactoylglutathione lyase activity
EXW51_10030	COG1271	oxidase subunit
EXW51_10035	COG1294	oxidase, subunit
EXW51_10040	COG4988	ABC transporter
EXW51_10045	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW51_10075	COG1686	Belongs to the peptidase S11 family
EXW51_10090	COG0791	NLP P60 protein
EXW51_10090	COG1388	LysM domain
EXW51_10100	COG1132	(ABC) transporter
EXW51_10105	COG0745	RESPONSE REGULATOR receiver
EXW51_10110	COG5002	protein histidine kinase activity
EXW51_10115	COG0300	oxidoreductase activity
EXW51_10120	COG4122	O-methyltransferase activity
EXW51_10150	COG0460	homoserine dehydrogenase
EXW51_10160	COG0083	homoserine kinase activity
EXW51_10175	COG1316	TRANSCRIPTIONal
EXW51_10195	COG1285	pathogenesis
EXW51_10200	COG1247	-acetyltransferase
EXW51_10220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW51_10230	COG1082	Xylose isomerase domain protein TIM barrel
EXW51_10240	COG2814	Major facilitator Superfamily
EXW51_10245	COG1279	arginine transmembrane transporter activity
EXW51_10250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW51_10260	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW51_10290	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW51_10295	COG0577	efflux transmembrane transporter activity
EXW51_10300	COG2002	toxin-antitoxin pair type II binding
EXW51_10305	COG1404	Belongs to the peptidase S8 family
EXW51_10310	COG0640	Transcriptional regulator
EXW51_10315	COG0667	Aldo Keto reductase
EXW51_10360	COG3949	Membrane
EXW51_10365	COG0783	Belongs to the Dps family
EXW51_10380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW51_10390	COG1231	oxidoreductase activity
EXW51_10395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW51_10400	COG4989	oxidoreductase activity
EXW51_10405	COG0523	cobalamin synthesis protein
EXW51_10420	COG0456	acetyltransferase
EXW51_10425	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW51_10445	COG2814	Major facilitator Superfamily
EXW51_10450	COG1136	(ABC) transporter
EXW51_10455	COG0577	efflux transmembrane transporter activity
EXW51_10460	COG0745	RESPONSE REGULATOR receiver
EXW51_10465	COG2205	protein histidine kinase activity
EXW51_10470	COG1902	pentaerythritol trinitrate reductase activity
EXW51_10475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW51_10485	COG4166	transmembrane transport
EXW51_10490	COG0346	lactoylglutathione lyase activity
EXW51_10500	COG0406	alpha-ribazole phosphatase activity
EXW51_10510	COG5337	Spore coat protein CotH
EXW51_10515	COG1051	belongs to the nudix hydrolase family
EXW51_10520	COG0586	Pfam SNARE associated Golgi protein
EXW51_10525	COG2244	polysaccharide biosynthetic process
EXW51_10535	COG0701	Predicted permease
EXW51_10540	COG3689	TIGRFAM TIGR03943 family protein
EXW51_10545	COG1607	acyl-coa hydrolase
EXW51_10555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW51_10570	COG0702	epimerase
EXW51_10575	COG2839	Protein conserved in bacteria
EXW51_10580	COG1253	flavin adenine dinucleotide binding
EXW51_10605	COG1114	Component of the transport system for branched-chain amino acids
EXW51_10610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW51_10630	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW51_10640	COG1876	peptidase activity
EXW51_10655	COG2211	Major facilitator Superfamily
EXW51_10670	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW51_10680	COG0561	phosphatase activity
EXW51_10685	COG1846	Transcriptional regulator
EXW51_10690	COG2814	Major facilitator Superfamily
EXW51_10700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW51_10720	COG1819	glycosyl
EXW51_10725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW51_10730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW51_10755	COG0456	acetyltransferase
EXW51_10790	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW51_10855	COG3874	Sporulation protein YtfJ
EXW51_10880	COG2226	methyltransferase
EXW51_10905	COG0346	lactoylglutathione lyase activity
EXW51_10915	COG0604	alcohol dehydrogenase
EXW51_10920	COG1595	DNA-templated transcription, initiation
EXW51_10955	COG0386	Belongs to the glutathione peroxidase family
EXW51_10960	COG1305	Transglutaminase-like
EXW51_10965	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW51_10970	COG0714	Associated with various cellular activities
EXW51_10975	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW51_10980	COG1140	nitrate reductase beta subunit
EXW51_10985	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW51_10990	COG2181	nitrate reductase activity
EXW51_10995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW51_11000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW51_11005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW51_11010	COG0303	'Molybdopterin
EXW51_11015	COG0314	molybdopterin synthase activity
EXW51_11025	COG2223	nitrite transmembrane transporter activity
EXW51_11045	COG1648	precorrin-2 dehydrogenase activity
EXW51_11055	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW51_11055	COG1587	Uroporphyrinogen-III synthase
EXW51_11060	COG2146	nitrite reductase [NAD(P)H] activity
EXW51_11065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW51_11070	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW51_11100	COG2359	stage V sporulation protein S
EXW51_11110	COG1418	mRNA catabolic process
EXW51_11115	COG0488	(ABC) transporter
EXW51_11135	COG1413	lyase activity
EXW51_11150	COG2521	methyltransferase
EXW51_11150	COG2136	Putative SAM-dependent methyltransferase
EXW51_11155	COG0018	arginyl-trna synthetase
EXW51_11210	COG0017	Asparaginyl-tRNA synthetase
EXW51_11215	COG0733	neurotransmitter:sodium symporter activity
EXW51_11240	COG2610	gluconate transmembrane transporter activity
EXW51_11250	COG1794	racemase activity, acting on amino acids and derivatives
EXW51_11260	COG0456	acetyltransferase
EXW51_11265	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW51_11275	COG1131	(ABC) transporter
EXW51_11280	COG4473	ABC transporter
EXW51_11290	COG0546	phosphoglycolate phosphatase activity
EXW51_11335	COG0768	penicillin binding
EXW51_11345	COG0204	Acyl-transferase
EXW51_11350	COG1272	protein, Hemolysin III
EXW51_11355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW51_11360	COG0805	protein transport
EXW51_11375	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW51_11380	COG1999	signal sequence binding
EXW51_11385	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW51_11390	COG0367	asparagine synthase
EXW51_11405	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW51_11410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW51_11415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW51_11435	COG1335	isochorismatase
EXW51_11445	COG0668	transmembrane transport
EXW51_11450	COG2203	Gaf domain
EXW51_11450	COG4585	Histidine kinase
EXW51_11455	COG2197	response regulator
EXW51_11460	COG1737	Transcriptional regulator
EXW51_11470	COG4974	Belongs to the 'phage' integrase family
EXW51_11480	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EXW51_11495	COG1064	alcohol dehydrogenase
EXW51_11510	COG1070	Carbohydrate kinase
EXW51_11520	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW51_11540	COG0517	IMP dehydrogenase activity
EXW51_11540	COG1125	glycine betaine transport
EXW51_11545	COG1174	glycine betaine transport
EXW51_11580	COG1253	flavin adenine dinucleotide binding
EXW51_11585	COG1012	belongs to the aldehyde dehydrogenase family
EXW51_11590	COG5506	Protein of unknown function (DUF1694)
EXW51_11605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW51_11610	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW51_11615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW51_11620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW51_11625	COG0456	acetyltransferase
EXW51_11630	COG3829	transcription factor binding
EXW51_11635	COG1509	lysine 2,3-aminomutase activity
EXW51_11645	COG4479	Belongs to the UPF0346 family
EXW51_11670	COG3064	Membrane
EXW51_11670	COG4991	sh3 domain protein
EXW51_11670	COG0515	serine threonine protein kinase
EXW51_11680	COG0671	phosphoesterase, PA-phosphatase related
EXW51_11685	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW51_11690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW51_11755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW51_11785	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_11805	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW51_11805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW51_11815	COG2814	Major facilitator Superfamily
EXW51_11825	COG0372	Belongs to the citrate synthase family
EXW51_11830	COG2079	MmgE PrpD family protein
EXW51_11835	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW51_11840	COG1960	acyl-CoA dehydrogenase activity
EXW51_11845	COG2084	Dehydrogenase
EXW51_11850	COG1012	belongs to the aldehyde dehydrogenase family
EXW51_11855	COG1280	lysine exporter protein (LysE YggA)
EXW51_11860	COG1024	Enoyl-CoA hydratase
EXW51_11875	COG0420	3'-5' exonuclease activity
EXW51_11895	COG2223	nitrite transmembrane transporter activity
EXW51_11900	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_11905	COG1169	isochorismate synthase
EXW51_11910	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW51_11915	COG1535	isochorismatase
EXW51_11915	COG3433	isochorismatase activity
EXW51_11920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW51_11925	COG3251	PFAM MbtH domain protein
EXW51_11930	COG2814	Major facilitator Superfamily
EXW51_11945	COG0776	regulation of translation
EXW51_11955	COG2318	DinB family
EXW51_11960	COG1115	amino acid carrier protein
EXW51_11965	COG2329	Antibiotic biosynthesis monooxygenase
EXW51_11980	COG1187	pseudouridine synthase activity
EXW51_11985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW51_11990	COG3655	Transcriptional regulator
EXW51_12000	COG1136	(ABC) transporter
EXW51_12010	COG0596	Alpha beta hydrolase
EXW51_12025	COG0028	Belongs to the TPP enzyme family
EXW51_12050	COG1253	flavin adenine dinucleotide binding
EXW51_12100	COG1846	Transcriptional regulator
EXW51_12115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW51_12120	COG1309	transcriptional regulator
EXW51_12155	COG1247	-acetyltransferase
EXW51_12190	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW51_12200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW51_12235	COG0583	DNA-binding transcription factor activity
EXW51_12240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW51_12245	COG2258	MOSC domain
EXW51_12260	COG1132	(ABC) transporter
EXW51_12265	COG1132	(ABC) transporter
EXW51_12285	COG1396	sequence-specific DNA binding
EXW51_12325	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW51_12330	COG1595	DNA-templated transcription, initiation
EXW51_12350	COG1649	PFAM Uncharacterised BCR, COG1649
EXW51_12370	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW51_12375	COG2971	BadF BadG BcrA BcrD
EXW51_12440	COG1309	transcriptional regulator
EXW51_12455	COG1136	(ABC) transporter
EXW51_12460	COG3615	Tellurite resistance protein tehB
EXW51_12460	COG0500	methyltransferase
EXW51_12475	COG0588	phosphoglycerate mutase activity
EXW51_12495	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW51_12505	COG0745	RESPONSE REGULATOR receiver
EXW51_12510	COG2205	protein histidine kinase activity
EXW51_12525	COG1136	(ABC) transporter
EXW51_12530	COG0577	efflux transmembrane transporter activity
EXW51_12550	COG1136	(ABC) transporter
EXW51_12580	COG1686	Belongs to the peptidase S11 family
EXW51_12605	COG0768	penicillin binding
EXW51_12610	COG1595	DNA-templated transcription, initiation
EXW51_12620	COG0768	penicillin binding
EXW51_12625	COG0768	penicillin binding
EXW51_12655	COG1252	NADH dehydrogenase
EXW51_12660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW51_12660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW51_12675	COG0697	spore germination
EXW51_12705	COG3397	chitin binding
EXW51_12710	COG0823	Involved in the tonB-independent uptake of proteins
EXW51_12720	COG1408	metallophosphoesterase
EXW51_12730	COG1131	(ABC) transporter
EXW51_12740	COG1309	transcriptional regulator
EXW51_12750	COG1960	acyl-CoA dehydrogenase activity
EXW51_12755	COG0439	Biotin carboxylase
EXW51_12760	COG0511	ligase activity, forming carbon-carbon bonds
EXW51_12765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW51_12770	COG1024	Enoyl-CoA hydratase
EXW51_12775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW51_12780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW51_12815	COG0572	uridine kinase
EXW51_12820	COG0596	Alpha beta hydrolase
EXW51_12825	COG2318	DinB family
EXW51_12830	COG1686	Belongs to the peptidase S11 family
EXW51_12855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW51_12880	COG2801	Transposase and inactivated derivatives
EXW51_12900	COG2207	Transcriptional regulator
EXW51_12960	COG1733	regulation of RNA biosynthetic process
EXW51_12985	COG1309	transcriptional regulator
EXW51_13015	COG0697	spore germination
EXW51_13020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW51_13055	COG2323	membrane
EXW51_13060	COG2132	Multicopper oxidase
EXW51_13075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW51_13080	COG0697	spore germination
EXW51_13085	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW51_13090	COG0201	protein transport
EXW51_13100	COG0737	Belongs to the 5'-nucleotidase family
EXW51_13110	COG3227	Zinc metalloprotease (Elastase)
EXW51_13115	COG1523	belongs to the glycosyl hydrolase 13 family
EXW51_13120	COG1073	alpha beta
EXW51_13130	COG0577	efflux transmembrane transporter activity
EXW51_13135	COG1136	(ABC) transporter
EXW51_13170	COG5002	protein histidine kinase activity
EXW51_13175	COG0745	RESPONSE REGULATOR receiver
EXW51_13180	COG1011	Hydrolase
EXW51_13205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW51_13210	COG1183	phosphatidylcholine synthase activity
EXW51_13220	COG1132	(ABC) transporter
EXW51_13225	COG3961	Belongs to the TPP enzyme family
EXW51_13245	COG0322	excinuclease ABC activity
EXW51_13270	COG2318	DinB family
EXW51_13285	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW51_13310	COG3878	Protein conserved in bacteria
EXW51_13335	COG1051	belongs to the nudix hydrolase family
EXW51_13340	COG0592	DNA-directed DNA polymerase activity
EXW51_13345	COG2816	NAD+ diphosphatase activity
EXW51_13355	COG2223	nitrite transmembrane transporter activity
EXW51_13360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW51_13370	COG0494	nUDIX hydrolase
EXW51_13390	COG0697	spore germination
EXW51_13395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW51_13415	COG0584	glycerophosphoryl diester phosphodiesterase
EXW51_13430	COG1733	regulation of RNA biosynthetic process
EXW51_13475	COG0768	penicillin binding
EXW51_13480	COG0671	phosphoesterase, PA-phosphatase related
EXW51_13485	COG0604	alcohol dehydrogenase
EXW51_13490	COG5002	protein histidine kinase activity
EXW51_13495	COG0745	RESPONSE REGULATOR receiver
EXW51_13505	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW51_13515	COG2205	protein histidine kinase activity
EXW51_13530	COG1122	ATPase activity
EXW51_13535	COG4720	Psort location CytoplasmicMembrane, score
EXW51_13540	COG1794	racemase activity, acting on amino acids and derivatives
EXW51_13545	COG1819	glycosyl
EXW51_13555	COG0768	penicillin binding
EXW51_13560	COG5002	protein histidine kinase activity
EXW51_13565	COG0561	phosphatase activity
EXW51_13605	COG2124	cytochrome p450
EXW51_13665	COG4824	toxin secretion phage lysis holin
EXW51_13785	COG0582	viral genome integration into host DNA
EXW51_13860	COG1484	DNA-dependent DNA replication
EXW51_13880	COG1396	sequence-specific DNA binding
EXW51_13895	COG0582	viral genome integration into host DNA
EXW51_13905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW51_13915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW51_13920	COG0460	homoserine dehydrogenase
EXW51_13940	COG0577	efflux transmembrane transporter activity
EXW51_13945	COG1136	(ABC) transporter
EXW51_13960	COG0488	(ABC) transporter
EXW51_13965	COG0667	Aldo Keto reductase
EXW51_13970	COG0583	DNA-binding transcription factor activity
EXW51_13975	COG2205	protein histidine kinase activity
EXW51_13980	COG0745	RESPONSE REGULATOR receiver
EXW51_13990	COG3773	Cell wall hydrolase
EXW51_13995	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW51_14005	COG3386	PFAM SMP-30 Gluconolaconase
EXW51_14045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW51_14060	COG2959	enzyme of heme biosynthesis
EXW51_14090	COG3483	tryptophan 2,3-dioxygenase activity
EXW51_14095	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW51_14100	COG3844	kynureninase activity
EXW51_14105	COG1309	transcriptional regulator
EXW51_14135	COG1349	DNA-binding transcription factor activity
EXW51_14160	COG1959	2 iron, 2 sulfur cluster binding
EXW51_14190	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_14195	COG0456	acetyltransferase
EXW51_14195	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW51_14225	COG4176	ABC-type proline glycine betaine transport system permease component
EXW51_14230	COG4175	Glycine betaine
EXW51_14230	COG0517	IMP dehydrogenase activity
EXW51_14255	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW51_14260	COG2153	protein acetylation
EXW51_14265	COG3397	chitin binding
EXW51_14275	COG1819	glycosyl
EXW51_14290	COG2205	protein histidine kinase activity
EXW51_14295	COG2315	Protein conserved in bacteria
EXW51_14340	COG3973	AAA domain
EXW51_14355	COG2105	PFAM AIG2 family protein
EXW51_14360	COG0514	ATP-dependent DNA helicase (RecQ)
EXW51_14380	COG4637	Psort location Cytoplasmic, score
EXW51_14390	COG1227	inorganic diphosphatase activity
EXW51_14395	COG3397	chitin binding
EXW51_14400	COG2318	DinB family
EXW51_14415	COG1162	GTPase activity
EXW51_14420	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW51_14425	COG1115	amino acid carrier protein
EXW51_14430	COG1012	belongs to the aldehyde dehydrogenase family
EXW51_14435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW51_14445	COG3938	Belongs to the proline racemase family
EXW51_14450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW51_14500	COG0586	Pfam SNARE associated Golgi protein
EXW51_14515	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW51_14520	COG4166	transmembrane transport
EXW51_14530	COG4948	Mandelate Racemase Muconate Lactonizing
EXW51_14550	COG0667	Aldo Keto reductase
EXW51_14595	COG2936	dipeptidyl-peptidase activity
EXW51_14605	COG0745	RESPONSE REGULATOR receiver
EXW51_14635	COG1164	Oligoendopeptidase f
EXW51_14665	COG1307	EDD domain protein, DegV family
EXW51_14695	COG1335	isochorismatase
EXW51_14710	COG2814	Major facilitator Superfamily
EXW51_14720	COG1664	Polymer-forming cytoskeletal
EXW51_14725	COG0789	Transcriptional regulator
EXW51_14730	COG4533	DNA binding
EXW51_14735	COG0477	Major facilitator Superfamily
EXW51_14735	COG2814	Major facilitator Superfamily
EXW51_14750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW51_14755	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW51_14760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW51_14765	COG0438	transferase activity, transferring glycosyl groups
EXW51_14780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW51_14785	COG0438	transferase activity, transferring glycosyl groups
EXW51_14790	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW51_14805	COG2261	transglycosylase associated protein
EXW51_14820	COG2226	methyltransferase
EXW51_14855	COG0436	Aminotransferase
EXW51_14860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW51_14870	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW51_14890	COG1131	(ABC) transporter
EXW51_14895	COG2188	Transcriptional regulator
EXW51_14940	COG0628	permease
EXW51_14975	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW51_14985	COG0697	spore germination
EXW51_14990	COG2318	DinB family
EXW51_15010	COG4912	Dna alkylation repair
EXW51_15040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW51_15050	COG2814	Major facilitator Superfamily
EXW51_15055	COG1368	sulfuric ester hydrolase activity
EXW51_15065	COG0488	(ABC) transporter
EXW51_15070	COG1033	growth of symbiont in host cell
EXW51_15070	COG2409	Drug exporters of the RND superfamily
EXW51_15080	COG1309	transcriptional regulator
EXW51_15100	COG0287	Prephenate dehydrogenase
EXW51_15115	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW51_15115	COG1605	Chorismate mutase
EXW51_15160	COG3584	3D domain protein
EXW51_15160	COG1388	LysM domain
EXW51_15170	COG0346	lactoylglutathione lyase activity
EXW51_15180	COG0277	FAD linked oxidase domain protein
EXW51_15195	COG1595	DNA-templated transcription, initiation
EXW51_15215	COG0579	oxidoreductase
EXW51_15220	COG1879	ABC-type sugar transport system periplasmic component
EXW51_15230	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW51_15235	COG1129	ABC transporter
EXW51_15240	COG2390	Transcriptional regulator
EXW51_15260	COG2226	methyltransferase
EXW51_15280	COG0346	lactoylglutathione lyase activity
EXW51_15285	COG2329	Antibiotic biosynthesis monooxygenase
EXW51_15305	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW51_15310	COG2207	Transcriptional regulator
EXW51_15315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW51_15320	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW51_15325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW51_15340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW51_15345	COG3239	Fatty acid desaturase
EXW51_15370	COG3655	Transcriptional regulator
EXW51_15385	COG4377	Putative membrane peptidase family (DUF2324)
EXW51_15395	COG3279	Response regulator of the LytR AlgR family
EXW51_15410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW51_15415	COG0346	lactoylglutathione lyase activity
EXW51_15445	COG0714	Associated with various cellular activities
EXW51_15465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW51_15470	COG0753	catalase activity
EXW51_15490	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW51_15510	COG0778	Nitroreductase
EXW51_15515	COG1846	Transcriptional regulator
EXW51_15535	COG0494	nUDIX hydrolase
EXW51_15540	COG2312	Erythromycin esterase
EXW51_15550	COG1136	(ABC) transporter
EXW51_15610	COG0456	acetyltransferase
EXW51_15625	COG0697	spore germination
EXW51_15630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW51_15635	COG1671	Belongs to the UPF0178 family
EXW51_15655	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW51_15655	COG0456	acetyltransferase
EXW51_15680	COG0730	response to heat
EXW51_15690	COG0833	amino acid
EXW51_15700	COG4335	DNA alkylation repair
EXW51_15720	COG0681	Belongs to the peptidase S26 family
EXW51_15725	COG0768	penicillin binding
EXW51_15740	COG3104	oligopeptide transport
EXW51_15745	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW51_15760	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW51_15765	COG1984	allophanate hydrolase subunit 2
EXW51_15770	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW51_15775	COG1414	Transcriptional regulator
EXW51_15795	COG1960	acyl-CoA dehydrogenase activity
EXW51_15835	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW51_15850	COG3848	Pyruvate phosphate dikinase
EXW51_15850	COG0574	Belongs to the PEP-utilizing enzyme family
EXW51_15865	COG0730	response to heat
EXW51_15900	COG5002	protein histidine kinase activity
EXW51_15905	COG0745	RESPONSE REGULATOR receiver
EXW51_15920	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW51_15940	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW51_15945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW51_15950	COG1121	(ABC) transporter
EXW51_15970	COG0798	PFAM Bile acid sodium symporter
EXW51_15975	COG0346	lactoylglutathione lyase activity
EXW51_15980	COG0640	Transcriptional regulator
EXW51_15995	COG1309	transcriptional regulator
EXW51_16000	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_16005	COG1522	sequence-specific DNA binding
EXW51_16020	COG0346	lactoylglutathione lyase activity
EXW51_16035	COG0457	Tetratricopeptide repeat
EXW51_16050	COG0745	RESPONSE REGULATOR receiver
EXW51_16055	COG3850	Histidine kinase
EXW51_16055	COG5002	protein histidine kinase activity
EXW51_16080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW51_16085	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW51_16110	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW51_16125	COG1136	(ABC) transporter
EXW51_16130	COG0577	efflux transmembrane transporter activity
EXW51_16150	COG5002	protein histidine kinase activity
EXW51_16150	COG3850	Histidine kinase
EXW51_16165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW51_16195	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW51_16215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW51_16275	COG2814	Major facilitator Superfamily
EXW51_16385	COG0477	Major facilitator Superfamily
EXW51_16400	COG1846	Transcriptional regulator
EXW51_16405	COG2814	Major facilitator Superfamily
EXW51_16420	COG0384	phenazine biosynthesis protein PhzF
EXW51_16465	COG4187	Peptidase family M20/M25/M40
EXW51_16470	COG1414	Transcriptional regulator
EXW51_16480	COG0833	amino acid
EXW51_16490	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW51_16495	COG2031	fatty acid transporter
EXW51_16505	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW51_16555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW51_16560	COG2356	endonuclease I
EXW51_16565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW51_16575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW51_16600	COG1785	Belongs to the alkaline phosphatase family
EXW51_16605	COG0778	Nitroreductase
EXW51_16610	COG1733	regulation of RNA biosynthetic process
EXW51_16630	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_16640	COG1131	(ABC) transporter
EXW51_16670	COG1011	Hydrolase
EXW51_16680	COG2365	Tyrosine phosphatase family
EXW51_16705	COG0346	lactoylglutathione lyase activity
EXW51_16710	COG1940	carbohydrate kinase activity
EXW51_16715	COG0738	Major facilitator superfamily
EXW51_16720	COG0110	maltose O-acetyltransferase activity
EXW51_16735	COG0628	permease
EXW51_16740	COG2261	transglycosylase associated protein
EXW51_16770	COG0477	Major facilitator Superfamily
EXW51_16785	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW51_16795	COG1253	flavin adenine dinucleotide binding
EXW51_16800	COG0789	Transcriptional regulator
EXW51_16810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW51_16835	COG0697	spore germination
EXW51_16840	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW51_16845	COG3813	Protein conserved in bacteria
EXW51_16850	COG4702	Belongs to the UPF0303 family
EXW51_16860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW51_16875	COG0494	nUDIX hydrolase
EXW51_16900	COG0318	PFAM AMP-dependent synthetase and ligase
EXW51_16905	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW51_16910	COG1733	regulation of RNA biosynthetic process
EXW51_16925	COG1191	sigma factor activity
EXW51_16950	COG1876	peptidase activity
EXW51_16970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW51_16985	COG0741	lytic transglycosylase activity
EXW51_17060	COG0657	acetylesterase activity
EXW51_17070	COG2814	Major facilitator Superfamily
EXW51_17075	COG1309	transcriptional regulator
EXW51_17090	COG3226	Transcriptional regulator
EXW51_17095	COG1280	lysine exporter protein (LysE YggA)
EXW51_17130	COG0814	amino acid
EXW51_17155	COG1151	hydroxylamine reductase activity
EXW51_17160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW51_17180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW51_17190	COG2072	flavoprotein involved in K transport
EXW51_17235	COG1695	Transcriptional regulator
EXW51_17240	COG0604	alcohol dehydrogenase
EXW51_17245	COG1113	amino acid transport
EXW51_17255	COG2814	Major facilitator Superfamily
EXW51_17275	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW51_17280	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW51_17310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW51_17315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW51_17320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW51_17325	COG3739	integral membrane protein
EXW51_17350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW51_17355	COG0583	DNA-binding transcription factor activity
EXW51_17375	COG1193	negative regulation of DNA recombination
EXW51_17385	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW51_17390	COG1164	Oligoendopeptidase f
EXW51_17395	COG2957	Belongs to the agmatine deiminase family
EXW51_17415	COG3781	membrane
EXW51_17430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW51_17470	COG3973	AAA domain
EXW51_17480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW51_17485	COG0640	Transcriptional regulator
EXW51_17490	COG0604	alcohol dehydrogenase
EXW51_17495	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW51_17505	COG0457	Tetratricopeptide repeat
EXW51_17510	COG2808	Putative FMN-binding domain
EXW51_17520	COG0277	FAD linked oxidase domain protein
EXW51_17540	COG1285	pathogenesis
EXW51_17550	COG2514	catechol 2,3-dioxygenase activity
EXW51_17555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW51_17560	COG1126	abc transporter atp-binding protein
EXW51_17565	COG0765	amino acid transport
EXW51_17570	COG2720	vancomycin resistance protein
EXW51_17595	COG1278	Cold shock
EXW51_17605	COG0716	FMN binding
EXW51_17615	COG0494	nUDIX hydrolase
EXW51_17635	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_17645	COG0165	Argininosuccinate lyase
EXW51_17660	COG4145	pantothenate transmembrane transporter activity
EXW51_17670	COG1012	belongs to the aldehyde dehydrogenase family
EXW51_17675	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_17685	COG1657	PFAM Prenyltransferase squalene oxidase
EXW51_17690	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW51_17695	COG2962	Rard protein
EXW51_17700	COG3326	Membrane
EXW51_17705	COG0531	amino acid
EXW51_17735	COG2226	methyltransferase
EXW51_17740	COG4166	transmembrane transport
EXW51_17745	COG4166	transmembrane transport
EXW51_17750	COG4166	transmembrane transport
EXW51_17755	COG1316	TRANSCRIPTIONal
EXW51_17765	COG1595	DNA-templated transcription, initiation
EXW51_17775	COG1131	(ABC) transporter
EXW51_17800	COG0673	inositol 2-dehydrogenase activity
EXW51_17810	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW51_17815	COG0187	DNA topoisomerase II activity
EXW51_17820	COG1832	CoA-binding protein
EXW51_17825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW51_17830	COG0745	RESPONSE REGULATOR receiver
EXW51_17840	COG1328	CTP reductase activity
EXW51_17840	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW51_17850	COG4841	protein insertion into membrane
EXW51_17855	COG0824	Thioesterase
EXW51_17880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW51_17900	COG2274	protein secretion by the type I secretion system
EXW51_17905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW51_17935	COG2211	Major facilitator Superfamily
EXW51_17945	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW51_17955	COG0457	Tetratricopeptide repeat
EXW51_17960	COG0183	Belongs to the thiolase family
EXW51_17965	COG0318	PFAM AMP-dependent synthetase and ligase
EXW51_17970	COG1268	BioY protein
EXW51_17975	COG0318	PFAM AMP-dependent synthetase and ligase
EXW51_17990	COG1396	sequence-specific DNA binding
EXW51_18015	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EXW51_18035	COG0830	nickel cation binding
EXW51_18075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW51_18090	COG5002	protein histidine kinase activity
EXW51_18100	COG0400	carboxylic ester hydrolase activity
EXW51_18105	COG0346	lactoylglutathione lyase activity
EXW51_18110	COG0069	glutamate synthase activity
EXW51_18115	COG1902	pentaerythritol trinitrate reductase activity
EXW51_18120	COG1329	Transcriptional regulator
EXW51_18125	COG0010	Belongs to the arginase family
EXW51_18135	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW51_18140	COG2986	histidine ammonia-lyase
EXW51_18150	COG2226	methyltransferase
EXW51_18180	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW51_18185	COG0785	Cytochrome C biogenesis protein
EXW51_18200	COG1473	amidohydrolase
EXW51_18205	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW51_18210	COG1131	(ABC) transporter
EXW51_18225	COG0583	DNA-binding transcription factor activity
EXW51_18235	COG1346	cytolysis
EXW51_18250	COG0730	response to heat
EXW51_18260	COG3409	Peptidoglycan-binding domain 1 protein
EXW51_18260	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW51_18280	COG1132	(ABC) transporter
EXW51_18285	COG1132	(ABC) transporter
EXW51_18290	COG3763	UPF0154 protein
EXW51_18310	COG3639	organic phosphonate transmembrane transporter activity
EXW51_18320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW51_18325	COG0737	Belongs to the 5'-nucleotidase family
EXW51_18335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW51_18340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW51_18355	COG1695	Transcriptional regulator
EXW51_18360	COG1132	(ABC) transporter
EXW51_18390	COG0367	asparagine synthase
EXW51_18395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW51_18405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW51_18410	COG3420	alginic acid biosynthetic process
EXW51_18410	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW51_18420	COG1442	glycosyl transferase family 8
EXW51_18425	COG1442	glycosyl transferase family 8
EXW51_18425	COG1216	Glycosyl transferase, family 2
EXW51_18440	COG0438	transferase activity, transferring glycosyl groups
EXW51_18450	COG0438	transferase activity, transferring glycosyl groups
EXW51_18460	COG1215	transferase activity, transferring glycosyl groups
EXW51_18465	COG0438	transferase activity, transferring glycosyl groups
EXW51_18470	COG0438	transferase activity, transferring glycosyl groups
EXW51_18475	COG1086	Polysaccharide biosynthesis protein
EXW51_18480	COG0489	protein tyrosine kinase activity
EXW51_18485	COG3944	biosynthesis protein
EXW51_18490	COG0174	glutamine synthetase
EXW51_18495	COG0789	Transcriptional regulator
EXW51_18500	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW51_18505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW51_18510	COG2860	membrane
EXW51_18515	COG0464	growth
EXW51_18535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW51_18545	COG1388	LysM domain
EXW51_18545	COG3584	3D domain protein
EXW51_18550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW51_18550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW51_18550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW51_18555	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW51_18560	COG1349	DNA-binding transcription factor activity
EXW51_18565	COG1979	alcohol dehydrogenase
EXW51_18570	COG2322	membrane
EXW51_18580	COG1113	amino acid transport
EXW51_18595	COG1473	amidohydrolase
EXW51_18600	COG1408	metallophosphoesterase
EXW51_18605	COG2116	formate transmembrane transporter activity
EXW51_18620	COG2217	Heavy metal translocating P-type atpase
EXW51_18625	COG2608	mercury ion transmembrane transporter activity
EXW51_18630	COG1937	Protein conserved in bacteria
EXW51_18660	COG4566	intracellular signal transduction
EXW51_18665	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW51_18670	COG2819	hydrolase of the alpha beta superfamily
EXW51_18675	COG1120	ATPase activity
EXW51_18680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW51_18685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW51_18690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW51_18695	COG0708	Exodeoxyribonuclease III
EXW51_18700	COG2169	Transcriptional regulator
EXW51_18705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW51_18710	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW51_18720	COG2706	6-phosphogluconolactonase activity
EXW51_18730	COG2364	Membrane
EXW51_18750	COG0346	lactoylglutathione lyase activity
EXW51_18755	COG5001	Diguanylate cyclase
EXW51_18755	COG3300	MHYT domain
EXW51_18795	COG1346	cytolysis
EXW51_18805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW51_18810	COG0596	Alpha beta hydrolase
EXW51_18810	COG2945	thiolester hydrolase activity
EXW51_18815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW51_18825	COG2188	Transcriptional regulator
EXW51_18830	COG2723	6-phospho-beta-galactosidase activity
EXW51_18845	COG1404	Belongs to the peptidase S8 family
EXW51_18850	COG3773	Cell wall hydrolase
EXW51_18865	COG1368	sulfuric ester hydrolase activity
EXW51_18870	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW51_18880	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW51_18890	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW51_18900	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW51_18905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW51_18910	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW51_18915	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW51_18915	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW51_18925	COG2359	stage V sporulation protein S
EXW51_18930	COG1692	metallophosphoesterase
EXW51_18935	COG1418	mRNA catabolic process
EXW51_18940	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW51_18945	COG1058	Belongs to the CinA family
EXW51_18945	COG1546	Belongs to the CinA family
EXW51_18950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW51_18955	COG1426	Protein conserved in bacteria
EXW51_18970	COG0300	oxidoreductase activity
EXW51_18975	COG0612	Peptidase, M16
EXW51_18980	COG0612	Peptidase, M16
EXW51_18985	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW51_18990	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW51_18995	COG3845	ABC transporter
EXW51_19000	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW51_19005	COG2188	Transcriptional regulator
EXW51_19015	COG1674	ftsk spoiiie
EXW51_19025	COG0740	serine-type endopeptidase activity
EXW51_19030	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW51_19040	COG0527	aspartate kinase activity
EXW51_19045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW51_19050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW51_19085	COG4824	toxin secretion phage lysis holin
EXW51_19200	COG0582	viral genome integration into host DNA
EXW51_19235	COG0305	Participates in initiation and elongation during chromosome replication
EXW51_19270	COG3620	sequence-specific DNA binding
EXW51_19305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW51_19310	COG1873	PFAM PRC-barrel domain
EXW51_19315	COG0612	Peptidase, M16
EXW51_19320	COG0726	polysaccharide deacetylase
EXW51_19325	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW51_19335	COG0196	riboflavin kinase activity
EXW51_19345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW51_19350	COG1550	Protein conserved in bacteria
EXW51_19355	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW51_19360	COG1358	cellular component organization or biogenesis
EXW51_19365	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW51_19370	COG0195	Participates in both transcription termination and antitermination
EXW51_19375	COG0779	Required for maturation of 30S ribosomal subunits
EXW51_19385	COG0442	prolyl-tRNA aminoacylation
EXW51_19390	COG0750	zinc metalloprotease
EXW51_19400	COG4589	Belongs to the CDS family
EXW51_19410	COG0233	cytoplasmic translational termination
EXW51_19415	COG0528	UMP kinase activity
EXW51_19420	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW51_19425	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW51_19430	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW51_19435	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW51_19440	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW51_19445	COG4974	Belongs to the 'phage' integrase family
EXW51_19450	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW51_19455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW51_19460	COG0758	DNA mediated transformation
EXW51_19465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW51_19470	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW51_19475	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW51_19490	COG0335	large ribosomal subunit rRNA binding
EXW51_19495	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW51_19500	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW51_19505	COG1837	Belongs to the UPF0109 family
EXW51_19515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW51_19520	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EXW51_19525	COG0552	protein localization to endoplasmic reticulum
EXW51_19530	COG1196	nuclear chromosome segregation
EXW51_19535	COG0571	ribonuclease III activity
EXW51_19540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW51_19545	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_19550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW51_19555	COG0416	fatty acid biosynthetic process
EXW51_19560	COG2050	protein possibly involved in aromatic compounds catabolism
EXW51_19560	COG1349	DNA-binding transcription factor activity
EXW51_19565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW51_19575	COG1461	Dihydroxyacetone kinase
EXW51_19580	COG1302	Protein conserved in bacteria
EXW51_19595	COG1564	THIamine pyrophosphokinase
EXW51_19600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW51_19610	COG0515	serine threonine protein kinase
EXW51_19610	COG2815	serine threonine protein kinase
EXW51_19615	COG0631	protein serine/threonine phosphatase activity
EXW51_19620	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW51_19625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW51_19625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW51_19630	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW51_19635	COG0242	peptide deformylase activity
EXW51_19640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW51_19645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW51_19650	COG1758	RNA polymerase activity
EXW51_19665	COG1561	YicC-like family, N-terminal region
EXW51_19670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW51_19685	COG0006	proline dipeptidase activity
EXW51_19705	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW51_19725	COG0167	dihydroorotate dehydrogenase activity
EXW51_19730	COG0543	2 iron, 2 sulfur cluster binding
EXW51_19735	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW51_19745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW51_19750	COG0540	Belongs to the ATCase OTCase family
EXW51_19760	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW51_19765	COG0564	pseudouridine synthase activity
EXW51_19770	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW51_19780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW51_19785	COG3599	regulation of cell shape
EXW51_19790	COG2302	S4 RNA-binding domain
EXW51_19795	COG0762	integral membrane protein
EXW51_19800	COG1799	cell septum assembly
EXW51_19805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW51_19815	COG1873	PFAM PRC-barrel domain
EXW51_19820	COG1191	sigma factor activity
EXW51_19825	COG1191	sigma factor activity
EXW51_19835	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW51_19840	COG0849	cell division
EXW51_19845	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW51_19860	COG0772	Belongs to the SEDS family
EXW51_19865	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW51_19870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW51_19875	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW51_19880	COG0768	penicillin binding
EXW51_19885	COG0768	penicillin binding
EXW51_19895	COG0275	rRNA processing
EXW51_19900	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW51_19905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW51_19910	COG0454	-acetyltransferase
EXW51_19920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW51_19925	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW51_19930	COG1323	Belongs to the UPF0348 family
EXW51_19935	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW51_19940	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW51_19945	COG3314	Sporulation integral membrane protein YlbJ
EXW51_19950	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EXW51_19955	COG0742	ribosomal rna small subunit methyltransferase
EXW51_19965	COG4471	UPF0298 protein
EXW51_19970	COG3679	Belongs to the UPF0342 family
EXW51_19975	COG0406	alpha-ribazole phosphatase activity
EXW51_19990	COG2340	Cysteine-rich secretory protein family
EXW51_20000	COG3336	cytochrome c oxidase
EXW51_20025	COG0109	protoheme IX farnesyltransferase activity
EXW51_20030	COG1612	heme a metabolic process
EXW51_20035	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW51_20045	COG0772	Belongs to the SEDS family
EXW51_20050	COG4838	Belongs to the UPF0358 family
EXW51_20055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW51_20060	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW51_20070	COG4896	Protein conserved in bacteria
EXW51_20085	COG1217	gtp-binding protein TYPA
EXW51_20095	COG0483	inositol monophosphate 1-phosphatase activity
EXW51_20105	COG4493	Belongs to the UPF0637 family
EXW51_20110	COG4476	Belongs to the UPF0223 family
EXW51_20115	COG1982	Orn Lys Arg decarboxylase major
EXW51_20160	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW51_20165	COG0022	dehydrogenase e1 component
EXW51_20170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW51_20185	COG0561	phosphatase activity
EXW51_20195	COG5503	Protein of unknown function (DUF1447)
EXW51_20200	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW51_20205	COG0569	domain protein
EXW51_20215	COG1473	amidohydrolase
EXW51_20220	COG2171	N-acyltransferase activity
EXW51_20225	COG0583	DNA-binding transcription factor activity
EXW51_20230	COG0517	IMP dehydrogenase activity
EXW51_20240	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW51_20250	COG4703	Protein of unknown function (DUF1797)
EXW51_20265	COG2200	EAL domain
EXW51_20270	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_20275	COG1408	metallophosphoesterase
EXW51_20320	COG2814	Major facilitator Superfamily
EXW51_20330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW51_20340	COG3209	COG3209 Rhs family protein
EXW51_20350	COG2205	protein histidine kinase activity
EXW51_20360	COG0436	Aminotransferase
EXW51_20365	COG1609	Transcriptional regulator
EXW51_20370	COG3833	ABC-type maltose transport systems, permease component
EXW51_20375	COG1175	transmembrane transport
EXW51_20380	COG2182	Extracellular solute-binding protein
EXW51_20390	COG0366	Alpha amylase catalytic
EXW51_20395	COG3842	ATPase activity
EXW51_20435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW51_20440	COG0183	Belongs to the thiolase family
EXW51_20480	COG1695	Transcriptional regulator
EXW51_20485	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_20495	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW51_20500	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW51_20505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW51_20510	COG0436	Aminotransferase
EXW51_20515	COG1850	ribulose-bisphosphate carboxylase activity
EXW51_20520	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW51_20525	COG0235	Class ii aldolase
EXW51_20530	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW51_20545	COG2084	Dehydrogenase
EXW51_20555	COG2199	diguanylate cyclase activity
EXW51_20560	COG0778	Nitroreductase
EXW51_20585	COG1263	PTS System
EXW51_20585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW51_20585	COG2190	(PTS) system
EXW51_20590	COG3711	transcriptional antiterminator
EXW51_20600	COG2188	Transcriptional regulator
EXW51_20605	COG0363	glucosamine-6-phosphate deaminase activity
EXW51_20610	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW51_20620	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW51_20630	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW51_20640	COG1547	Domain of unknown function (DUF309)
EXW51_20650	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW51_20655	COG4086	secreted protein
EXW51_20660	COG0561	phosphatase activity
EXW51_20665	COG0697	spore germination
EXW51_20680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW51_20720	COG1686	Belongs to the peptidase S11 family
EXW51_20725	COG1725	Transcriptional regulator
EXW51_20730	COG1131	(ABC) transporter
EXW51_20750	COG1846	Transcriptional regulator
EXW51_20765	COG0598	Magnesium transport protein CorA
EXW51_20780	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW51_20790	COG4974	Belongs to the 'phage' integrase family
EXW51_20800	COG0735	belongs to the Fur family
EXW51_20805	COG1300	Membrane
EXW51_20825	COG0667	Aldo Keto reductase
EXW51_20830	COG0656	L-ascorbic acid biosynthetic process
EXW51_20835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW51_20835	COG0456	acetyltransferase
EXW51_20845	COG0737	Belongs to the 5'-nucleotidase family
EXW51_20845	COG1525	nuclease
EXW51_20845	COG4085	toxin activity
EXW51_20850	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW51_20860	COG0596	Alpha beta hydrolase
EXW51_20865	COG2056	Na+-H+ antiporter family
EXW51_20870	COG1609	Transcriptional regulator
EXW51_20875	COG0456	acetyltransferase
EXW51_20880	COG1073	alpha beta
EXW51_20895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW51_20895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW51_20900	COG0307	riboflavin synthase, alpha
EXW51_20905	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW51_20905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW51_20920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW51_20925	COG4106	trans-aconitate 2-methyltransferase activity
EXW51_20930	COG2226	methyltransferase
EXW51_20930	COG1073	alpha beta
EXW51_20935	COG0156	8-amino-7-oxononanoate synthase activity
EXW51_20945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW51_20960	COG1757	Na H antiporter
EXW51_20965	COG0737	Belongs to the 5'-nucleotidase family
EXW51_20975	COG1522	sequence-specific DNA binding
EXW51_21010	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW51_21020	COG0300	oxidoreductase activity
EXW51_21025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW51_21030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW51_21035	COG1760	l-serine dehydratase
EXW51_21040	COG1760	l-serine dehydratase
EXW51_21050	COG1234	tRNA 3'-trailer cleavage
EXW51_21085	COG1131	(ABC) transporter
EXW51_21105	COG1285	pathogenesis
EXW51_21120	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW51_21125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW51_21135	COG1376	ErfK ybiS ycfS ynhG family protein
EXW51_21140	COG4129	membrane
EXW51_21145	COG1126	abc transporter atp-binding protein
EXW51_21150	COG0765	amino acid transport
EXW51_21155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW51_21170	COG2816	NAD+ diphosphatase activity
EXW51_21175	COG2323	membrane
EXW51_21180	COG0772	Belongs to the SEDS family
EXW51_21190	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW51_21195	COG0022	dehydrogenase e1 component
EXW51_21200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW51_21205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW51_21210	COG3426	butyrate kinase activity
EXW51_21220	COG0280	phosphate acetyltransferase
EXW51_21230	COG3290	protein histidine kinase activity
EXW51_21230	COG3829	transcription factor binding
EXW51_21240	COG0584	glycerophosphoryl diester phosphodiesterase
EXW51_21245	COG3093	addiction module antidote protein HigA
EXW51_21275	COG0745	RESPONSE REGULATOR receiver
EXW51_21285	COG0750	zinc metalloprotease
EXW51_21290	COG0497	DNA recombination
EXW51_21295	COG1438	arginine binding
EXW51_21300	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW51_21305	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW51_21310	COG0142	geranyltranstransferase activity
EXW51_21315	COG1722	exodeoxyribonuclease VII activity
EXW51_21320	COG1570	exodeoxyribonuclease VII activity
EXW51_21325	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW51_21330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW51_21335	COG1302	Protein conserved in bacteria
EXW51_21340	COG0439	Biotin carboxylase
EXW51_21345	COG0511	ligase activity, forming carbon-carbon bonds
EXW51_21390	COG3854	ATPases associated with a variety of cellular activities
EXW51_21410	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW51_21415	COG0006	proline dipeptidase activity
EXW51_21420	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW51_21430	COG3872	metal-dependent enzyme
EXW51_21440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW51_21445	COG1321	iron dependent repressor
EXW51_21480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW51_21490	COG1609	Transcriptional regulator
EXW51_21500	COG2076	Multidrug Resistance protein
EXW51_21505	COG2076	Multidrug Resistance protein
EXW51_21540	COG1725	Transcriptional regulator
EXW51_21560	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW51_21565	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW51_21570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW51_21575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW51_21605	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW51_21630	COG4970	Tfp pilus assembly protein FimT
EXW51_21640	COG1459	type II secretion system
EXW51_21645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW51_21700	COG1410	methionine synthase
EXW51_21700	COG0646	methionine synthase
EXW51_21705	COG0646	methionine synthase
EXW51_21705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW51_21710	COG0626	cystathionine gamma-synthase activity
EXW51_21715	COG0626	cystathionine gamma-synthase activity
EXW51_21730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW51_21740	COG1940	carbohydrate kinase activity
EXW51_21745	COG4483	Protein conserved in bacteria
EXW51_21750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW51_21755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW51_21760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW51_21765	COG0704	Plays a role in the regulation of phosphate uptake
EXW51_21775	COG0581	inorganic phosphate transmembrane transporter activity
EXW51_21780	COG0573	inorganic phosphate transmembrane transporter activity
EXW51_21785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW51_21790	COG0768	penicillin binding
EXW51_21795	COG0477	Major facilitator Superfamily
EXW51_21800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW51_21820	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW51_21825	COG0735	belongs to the Fur family
EXW51_21830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW51_21835	COG1121	(ABC) transporter
EXW51_21840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW51_21850	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW51_21865	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW51_21870	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW51_21875	COG2384	SAM-dependent methyltransferase
EXW51_21885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW51_21890	COG0358	DNA primase activity
EXW51_21900	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW51_21905	COG0517	IMP dehydrogenase activity
EXW51_21910	COG1381	Involved in DNA repair and RecF pathway recombination
EXW51_21920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW51_21925	COG0295	cytidine deaminase activity
EXW51_21930	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW51_21935	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW51_21940	COG1480	7TM receptor with intracellular HD hydrolase
EXW51_21945	COG1702	phosphate starvation-inducible protein PhoH
EXW51_21960	COG1610	YqeY-like protein
EXW51_21965	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW51_21970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW51_21975	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW51_21985	COG0484	heat shock protein binding
EXW51_21990	COG0443	Heat shock 70 kDa protein
EXW51_22000	COG1420	regulation of RNA biosynthetic process
EXW51_22005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW51_22010	COG1733	regulation of RNA biosynthetic process
EXW51_22015	COG0481	GTPase activity
EXW51_22025	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW51_22030	COG0268	Binds directly to 16S ribosomal RNA
EXW51_22035	COG1466	dna polymerase III delta subunit
EXW51_22045	COG0658	competence protein
EXW51_22045	COG2333	competence protein COMEC
EXW51_22050	COG2131	deaminase
EXW51_22055	COG1555	photosystem II stabilization
EXW51_22055	COG1596	polysaccharide export
EXW51_22060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW51_22065	COG2226	methyltransferase
EXW51_22070	COG0799	negative regulation of ribosome biogenesis
EXW51_22075	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW51_22080	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW51_22085	COG1534	Rna-binding protein
EXW51_22090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW51_22095	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW51_22100	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW51_22110	COG0688	phosphatidylethanolamine metabolic process
EXW51_22130	COG2357	RelA SpoT domain protein
EXW51_22140	COG1785	Belongs to the alkaline phosphatase family
EXW51_22150	COG2267	carboxylic ester hydrolase activity
EXW51_22190	COG1404	Belongs to the peptidase S8 family
EXW51_22200	COG3186	Phenylalanine-4-hydroxylase
EXW51_22210	COG2514	catechol 2,3-dioxygenase activity
EXW51_22215	COG2259	Doxx family
EXW51_22255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW51_22265	COG1012	belongs to the aldehyde dehydrogenase family
EXW51_22265	COG1454	alcohol dehydrogenase
EXW51_22270	COG0626	cystathionine gamma-synthase activity
EXW51_22275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW51_22280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW51_22285	COG2226	methyltransferase
EXW51_22300	COG0768	penicillin binding
EXW51_22305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW51_22310	COG0572	uridine kinase
EXW51_22315	COG0826	peptidase U32
EXW51_22320	COG0826	peptidase U32
EXW51_22325	COG4122	O-methyltransferase activity
EXW51_22330	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW51_22340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW51_22345	COG4472	Bacterial protein of unknown function (DUF965)
EXW51_22350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW51_22355	COG0628	permease
EXW51_22375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW51_22385	COG0482	sulfurtransferase activity
EXW51_22390	COG1104	cysteine desulfurase activity
EXW51_22395	COG1959	2 iron, 2 sulfur cluster binding
EXW51_22400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW51_22410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW51_22415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW51_22425	COG1490	D-aminoacyl-tRNA deacylase activity
EXW51_22430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW51_22435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW51_22440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW51_22440	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW51_22445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW51_22450	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW51_22450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW51_22460	COG2244	polysaccharide biosynthetic process
EXW51_22465	COG2323	membrane
EXW51_22475	COG1862	Preprotein translocase
EXW51_22480	COG0343	queuine tRNA-ribosyltransferase activity
EXW51_22485	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW51_22495	COG2255	four-way junction helicase activity
EXW51_22500	COG0632	four-way junction helicase activity
EXW51_22505	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW51_22535	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW51_22540	COG0157	Belongs to the NadC ModD family
EXW51_22545	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW51_22550	COG1104	cysteine desulfurase activity
EXW51_22555	COG1827	regulation of RNA biosynthetic process
EXW51_22560	COG2258	MOSC domain
EXW51_22565	COG0077	Prephenate dehydratase
EXW51_22570	COG0577	efflux transmembrane transporter activity
EXW51_22575	COG0577	efflux transmembrane transporter activity
EXW51_22580	COG1136	(ABC) transporter
EXW51_22585	COG5002	protein histidine kinase activity
EXW51_22590	COG0745	RESPONSE REGULATOR receiver
EXW51_22595	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW51_22600	COG3290	protein histidine kinase activity
EXW51_22610	COG2868	ribosomal protein
EXW51_22620	COG1530	ribonuclease E activity
EXW51_22625	COG1994	Peptidase M50
EXW51_22630	COG0739	heme binding
EXW51_22635	COG2894	cell division
EXW51_22640	COG0850	regulation of cytokinetic process
EXW51_22655	COG1077	Cell shape determining protein MreB Mrl
EXW51_22660	COG2003	Belongs to the UPF0758 family
EXW51_22665	COG0424	maF-like protein
EXW51_22680	COG0285	dihydrofolate synthase activity
EXW51_22695	COG1388	LysM domain
EXW51_22700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW51_22705	COG0113	porphobilinogen synthase activity
EXW51_22710	COG1587	Uroporphyrinogen-III synthase
EXW51_22715	COG0181	hydroxymethylbilane synthase activity
EXW51_22720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW51_22725	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW51_22730	COG1846	Transcriptional regulator
EXW51_22735	COG1764	response to oxidative stress
EXW51_22740	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW51_22750	COG0470	DNA polymerase III
EXW51_22750	COG1067	ATP-dependent peptidase activity
EXW51_22760	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW51_22790	COG0622	Phosphoesterase
EXW51_22800	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW51_22805	COG5401	PFAM Sporulation and spore germination
EXW51_22825	COG2197	response regulator
EXW51_22830	COG2233	PERMEase
EXW51_22835	COG0402	S-adenosylhomocysteine deaminase activity
EXW51_22840	COG1983	PspC domain protein
EXW51_22845	COG1396	sequence-specific DNA binding
EXW51_22850	COG0697	spore germination
EXW51_22860	COG1959	2 iron, 2 sulfur cluster binding
EXW51_22865	COG1668	transmembrane transport
EXW51_22870	COG4152	abc transporter atp-binding protein
EXW51_22875	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW51_22880	COG1360	Flagellar Motor Protein
EXW51_22885	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW51_22895	COG1876	peptidase activity
EXW51_22900	COG0824	Thioesterase
EXW51_22905	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW51_22910	COG1053	succinate dehydrogenase
EXW51_22915	COG2009	succinate dehydrogenase
EXW51_22920	COG1719	4-vinyl reductase, 4VR
EXW51_22925	COG0322	excinuclease ABC activity
EXW51_22930	COG3118	belongs to the thioredoxin family
EXW51_22935	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW51_22940	COG2086	electron transfer activity
EXW51_22945	COG1024	Enoyl-CoA hydratase
EXW51_22950	COG1309	transcriptional regulator
EXW51_22955	COG0318	PFAM AMP-dependent synthetase and ligase
EXW51_22970	COG2318	DinB family
EXW51_22995	COG1131	(ABC) transporter
EXW51_23000	COG2205	protein histidine kinase activity
EXW51_23005	COG0745	RESPONSE REGULATOR receiver
EXW51_23010	COG4895	conserved protein (DUF2196)
EXW51_23015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW51_23025	COG2329	Antibiotic biosynthesis monooxygenase
EXW51_23030	COG4509	Sortase family
EXW51_23035	COG1120	ATPase activity
EXW51_23050	COG5386	Cell surface protein
EXW51_23060	COG5386	Cell surface protein
EXW51_23065	COG1114	Component of the transport system for branched-chain amino acids
EXW51_23075	COG1193	negative regulation of DNA recombination
EXW51_23080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW51_23080	COG1796	DNA polymerase
EXW51_23085	COG1286	toxin biosynthetic process
EXW51_23090	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW51_23095	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW51_23130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW51_23135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW51_23150	COG1418	mRNA catabolic process
EXW51_23170	COG2814	Major facilitator Superfamily
EXW51_23175	COG1566	PFAM secretion protein HlyD family protein
EXW51_23180	COG1309	transcriptional regulator
EXW51_23185	COG1363	Peptidase, m42
EXW51_23195	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW51_23210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW51_23225	COG1484	DNA-dependent DNA replication
EXW51_23230	COG3611	Membrane attachment protein
EXW51_23235	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW51_23240	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW51_23245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW51_23250	COG0237	dephospho-CoA kinase activity
EXW51_23255	COG1971	Probably functions as a manganese efflux pump
EXW51_23265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW51_23265	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW51_23270	COG5002	protein histidine kinase activity
EXW51_23275	COG0745	RESPONSE REGULATOR receiver
EXW51_23295	COG0538	isocitrate dehydrogenase activity
EXW51_23300	COG0372	Belongs to the citrate synthase family
EXW51_23315	COG0628	permease
EXW51_23320	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW51_23330	COG0205	6-phosphofructokinase activity
EXW51_23340	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW51_23345	COG1725	Transcriptional regulator
EXW51_23350	COG0281	malic enzyme
EXW51_23355	COG0587	DNA-directed DNA polymerase activity
EXW51_23370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW51_23390	COG4109	DRTGG domain
EXW51_23395	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW51_23400	COG0006	proline dipeptidase activity
EXW51_23430	COG0662	Cupin 2, conserved barrel domain protein
EXW51_23440	COG1476	TRANSCRIPTIONal
EXW51_23455	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_23460	COG0589	response to stress
EXW51_23490	COG0137	argininosuccinate synthase activity
EXW51_23505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW51_23520	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW51_23525	COG0827	DNA restriction-modification system
EXW51_23530	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW51_23535	COG3874	Sporulation protein YtfJ
EXW51_23550	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW51_23560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW51_23575	COG1104	cysteine desulfurase activity
EXW51_23580	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW51_23595	COG1309	transcriptional regulator
EXW51_23600	COG1956	GAF domain-containing protein
EXW51_23605	COG0626	cystathionine gamma-synthase activity
EXW51_23610	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW51_23640	COG1595	DNA-templated transcription, initiation
EXW51_23650	COG0110	maltose O-acetyltransferase activity
EXW51_23660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW51_23665	COG0454	-acetyltransferase
EXW51_23670	COG0517	IMP dehydrogenase activity
EXW51_23675	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW51_23695	COG1970	mechanosensitive ion channel activity
EXW51_23715	COG1609	Transcriptional regulator
EXW51_23720	COG1605	Chorismate mutase
EXW51_23720	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW51_23725	COG1605	Chorismate mutase
EXW51_23725	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW51_23730	COG4851	CamS sex pheromone cAM373 precursor
EXW51_23735	COG3118	belongs to the thioredoxin family
EXW51_23745	COG2309	aminopeptidase activity
EXW51_23765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW51_23770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW51_23780	COG1674	ftsk spoiiie
EXW51_23795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW51_23800	COG4848	Belongs to the UPF0354 family
EXW51_23805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW51_23810	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW51_23815	COG1363	Peptidase, m42
EXW51_23825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW51_23830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW51_23840	COG0510	thiamine kinase activity
EXW51_23845	COG1523	belongs to the glycosyl hydrolase 13 family
EXW51_23860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW51_23865	COG1349	DNA-binding transcription factor activity
EXW51_23870	COG1187	pseudouridine synthase activity
EXW51_23875	COG2244	polysaccharide biosynthetic process
EXW51_23880	COG2081	HI0933 family
EXW51_23885	COG2814	Major facilitator Superfamily
EXW51_23895	COG3832	glyoxalase III activity
EXW51_23915	COG1329	Transcriptional regulator
EXW51_23940	COG0314	molybdopterin synthase activity
EXW51_23945	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW51_23950	COG0303	'Molybdopterin
EXW51_23955	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW51_23960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW51_23965	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW51_23985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW51_23995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW51_24040	COG2814	Major facilitator Superfamily
EXW51_24045	COG0475	glutathione-regulated potassium exporter activity
EXW51_24050	COG0490	domain, Protein
EXW51_24055	COG0582	viral genome integration into host DNA
EXW51_24070	COG1136	(ABC) transporter
EXW51_24090	COG1242	4 iron, 4 sulfur cluster binding
EXW51_24095	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW51_24100	COG1131	(ABC) transporter
EXW51_24110	COG1794	racemase activity, acting on amino acids and derivatives
EXW51_24130	COG2267	carboxylic ester hydrolase activity
EXW51_24135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW51_24140	COG0671	phosphoesterase, PA-phosphatase related
EXW51_24145	COG0438	transferase activity, transferring glycosyl groups
EXW51_24155	COG1404	Belongs to the peptidase S8 family
EXW51_24160	COG1404	Belongs to the peptidase S8 family
EXW51_24170	COG4585	Histidine kinase
EXW51_24175	COG0746	molybdenum cofactor guanylyltransferase activity
EXW51_24195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW51_24200	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW51_24230	COG5002	protein histidine kinase activity
EXW51_24235	COG3852	Histidine kinase
EXW51_24240	COG0753	catalase activity
EXW51_24245	COG2267	carboxylic ester hydrolase activity
EXW51_24255	COG1368	sulfuric ester hydrolase activity
EXW51_24265	COG4895	conserved protein (DUF2196)
EXW51_24280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW51_24285	COG1116	anion transmembrane transporter activity
EXW51_24290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW51_24315	COG0494	nUDIX hydrolase
EXW51_24345	COG1854	S-ribosylhomocysteine lyase activity
EXW51_24355	COG0288	reversible hydration of carbon dioxide
EXW51_24360	COG1271	oxidase subunit
EXW51_24365	COG1294	oxidase, subunit
EXW51_24385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW51_24410	COG1842	Phage shock protein A
EXW51_24435	COG3859	Proton-coupled thiamine transporter YuaJ
EXW51_24440	COG5002	protein histidine kinase activity
EXW51_24445	COG0745	RESPONSE REGULATOR receiver
EXW51_24470	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW51_24475	COG1597	lipid kinase activity
EXW51_24490	COG1136	(ABC) transporter
EXW51_24505	COG5002	protein histidine kinase activity
EXW51_24515	COG0586	Pfam SNARE associated Golgi protein
EXW51_24525	COG0577	efflux transmembrane transporter activity
EXW51_24530	COG1136	(ABC) transporter
EXW51_24535	COG2207	Transcriptional regulator
EXW51_24535	COG3708	Transcriptional regulator
EXW51_24545	COG1131	(ABC) transporter
EXW51_24555	COG5658	integral membrane protein
EXW51_24560	COG0640	Transcriptional regulator
EXW51_24565	COG0745	RESPONSE REGULATOR receiver
EXW51_24570	COG2205	protein histidine kinase activity
EXW51_24575	COG0577	efflux transmembrane transporter activity
EXW51_24580	COG0577	efflux transmembrane transporter activity
EXW51_24585	COG1136	(ABC) transporter
EXW51_24590	COG0577	efflux transmembrane transporter activity
EXW51_24605	COG2188	Transcriptional regulator
EXW51_24625	COG3964	amidohydrolase
EXW51_24645	COG4948	Mandelate Racemase Muconate Lactonizing
EXW51_24650	COG0318	PFAM AMP-dependent synthetase and ligase
EXW51_24655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW51_24660	COG0596	Alpha beta hydrolase
EXW51_24665	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW51_24670	COG1169	isochorismate synthase
EXW51_24675	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW51_24680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW51_24685	COG1278	Cold shock
EXW51_24695	COG0789	Transcriptional regulator
EXW51_24705	COG0058	SHG alpha-glucan phosphorylase activity
EXW51_24715	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW51_24720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW51_24725	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW51_24740	COG1309	transcriptional regulator
EXW51_24875	COG1285	pathogenesis
EXW51_24880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW51_24890	COG0166	Belongs to the GPI family
EXW51_24900	COG2155	Conserved Protein
EXW51_24905	COG1098	S1 RNA binding domain
EXW51_24910	COG0436	Aminotransferase
EXW51_24915	COG1522	sequence-specific DNA binding
EXW51_24920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW51_24925	COG2267	carboxylic ester hydrolase activity
EXW51_24935	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW51_24950	COG5018	Exonuclease
EXW51_24955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW51_24975	COG2050	protein possibly involved in aromatic compounds catabolism
EXW51_24985	COG1268	BioY protein
EXW51_24995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW51_25000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW51_25010	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW51_25015	COG3584	3D domain protein
EXW51_25040	COG1252	NADH dehydrogenase
EXW51_25045	COG0492	ferredoxin-NADP+ reductase activity
EXW51_25050	COG3708	Transcriptional regulator
EXW51_25065	COG1683	Conserved Protein
EXW51_25075	COG0316	Belongs to the HesB IscA family
EXW51_25080	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW51_25085	COG4844	belongs to the
EXW51_25090	COG1252	NADH dehydrogenase
EXW51_25100	COG0390	transport system, permease component
EXW51_25105	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW51_25140	COG4837	Protein of unknown function (DUF1462)
EXW51_25145	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW51_25155	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW51_25160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW51_25195	COG1136	(ABC) transporter
EXW51_25215	COG1132	(ABC) transporter
EXW51_25235	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW51_25245	COG0647	UMP catabolic process
EXW51_25255	COG2445	Protein of unknown function DUF86
EXW51_25260	COG1494	fructose-1,6-bisphosphatase
EXW51_25280	COG4470	Protein conserved in bacteria
EXW51_25290	COG0789	Transcriptional regulator
EXW51_25295	COG4377	Putative membrane peptidase family (DUF2324)
EXW51_25315	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW51_25320	COG0739	heme binding
EXW51_25330	COG3377	Domain of unknown function (DUF1805)
EXW51_25335	COG0737	Belongs to the 5'-nucleotidase family
EXW51_25340	COG0719	Fe-S assembly protein
EXW51_25345	COG0822	iron-sulfur transferase activity
EXW51_25350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW51_25355	COG0719	Fe-S assembly protein
EXW51_25360	COG0396	ATPase activity
EXW51_25365	COG1464	Belongs to the NlpA lipoprotein family
EXW51_25370	COG1464	Belongs to the NlpA lipoprotein family
EXW51_25375	COG2011	ABC-type metal ion transport system permease component
EXW51_25395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW51_25400	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW51_25405	COG0509	glycine decarboxylation via glycine cleavage system
EXW51_25410	COG1393	Belongs to the ArsC family
EXW51_25445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW51_25460	COG1960	acyl-CoA dehydrogenase activity
EXW51_25465	COG0183	Belongs to the thiolase family
EXW51_25470	COG1024	Enoyl-CoA hydratase
EXW51_25470	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW51_25480	COG1686	Belongs to the peptidase S11 family
EXW51_25485	COG0506	proline dehydrogenase activity
EXW51_25495	COG0011	TIGRFAM Protein of
EXW51_25500	COG0840	transmembrane signaling receptor activity
EXW51_25510	COG2814	Major facilitator Superfamily
EXW51_25515	COG0531	amino acid
EXW51_25535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW51_25565	COG0586	Pfam SNARE associated Golgi protein
EXW51_25575	COG1376	ErfK ybiS ycfS ynhG family protein
EXW51_25580	COG0745	RESPONSE REGULATOR receiver
EXW51_25585	COG5002	protein histidine kinase activity
EXW51_25595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW51_25605	COG0840	transmembrane signaling receptor activity
EXW51_25610	COG0840	transmembrane signaling receptor activity
EXW51_25615	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW51_25620	COG3227	Zinc metalloprotease (Elastase)
EXW51_25625	COG1741	Belongs to the pirin family
EXW51_25640	COG0586	Pfam SNARE associated Golgi protein
EXW51_25645	COG0475	glutathione-regulated potassium exporter activity
EXW51_25650	COG0490	domain, Protein
EXW51_25655	COG1115	amino acid carrier protein
EXW51_25660	COG0783	Belongs to the Dps family
EXW51_25670	COG2318	DinB family
EXW51_25680	COG1611	Belongs to the LOG family
EXW51_25690	COG1528	Iron-storage protein
EXW51_25695	COG2311	Membrane
EXW51_25705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW51_25710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW51_25715	COG1115	amino acid carrier protein
EXW51_25720	COG2910	NAD(P)H-binding
EXW51_25735	COG0656	L-ascorbic acid biosynthetic process
EXW51_25740	COG2814	Major facilitator Superfamily
EXW51_25745	COG1733	regulation of RNA biosynthetic process
EXW51_25755	COG1252	NADH dehydrogenase
EXW51_25760	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EXW51_25775	COG0840	transmembrane signaling receptor activity
EXW51_25775	COG3290	protein histidine kinase activity
EXW51_25810	COG0488	(ABC) transporter
EXW51_25815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW51_25840	COG1522	sequence-specific DNA binding
EXW51_25845	COG0288	reversible hydration of carbon dioxide
EXW51_25850	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW51_25855	COG2233	PERMEase
EXW51_25880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW51_25920	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW51_25930	COG0557	exoribonuclease II activity
EXW51_25935	COG1647	Serine aminopeptidase, S33
EXW51_25940	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW51_25945	COG1346	cytolysis
EXW51_25960	COG0148	phosphopyruvate hydratase activity
EXW51_25970	COG0149	triose-phosphate isomerase activity
EXW51_25975	COG0126	phosphoglycerate kinase activity
EXW51_25980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW51_25995	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW51_26020	COG5294	Protein conserved in bacteria
EXW51_26040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW51_26055	COG2323	membrane
EXW51_26070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW51_26075	COG1481	regulation of sporulation
EXW51_26080	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW51_26085	COG1660	Displays ATPase and GTPase activities
EXW51_26090	COG1051	belongs to the nudix hydrolase family
EXW51_26100	COG0492	ferredoxin-NADP+ reductase activity
EXW51_26105	COG0457	Tetratricopeptide repeat
EXW51_26110	COG0110	maltose O-acetyltransferase activity
EXW51_26115	COG0546	phosphoglycolate phosphatase activity
EXW51_26120	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW51_26125	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW51_26130	COG1950	PFAM Membrane protein of
EXW51_26135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW51_26155	COG0789	Transcriptional regulator
EXW51_26190	COG0583	DNA-binding transcription factor activity
EXW51_26195	COG0789	Transcriptional regulator
EXW51_26200	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW51_26205	COG0488	(ABC) transporter
EXW51_26215	COG1132	(ABC) transporter
EXW51_26220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW51_26225	COG3409	Peptidoglycan-binding domain 1 protein
EXW51_26225	COG0793	Belongs to the peptidase S41A family
EXW51_26230	COG2177	Part of the ABC transporter FtsEX involved in
EXW51_26235	COG2884	Cell division ATP-binding protein ftsE
EXW51_26275	COG1278	Cold shock
EXW51_26280	COG1040	competence protein
EXW51_26285	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW51_26290	COG1388	LysM domain
EXW51_26290	COG0791	NLP P60 protein
EXW51_26295	COG1733	regulation of RNA biosynthetic process
EXW51_26300	COG1307	EDD domain protein, DegV family
EXW51_26305	COG1739	Uncharacterized protein family UPF0029
EXW51_26310	COG1316	TRANSCRIPTIONal
EXW51_26315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW51_26320	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW51_26325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW51_26340	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW51_26340	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW51_26360	COG1486	melibiose metabolic process
EXW51_26365	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW51_26370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW51_26390	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW51_26400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW51_26405	COG1301	dicarboxylic acid transport
EXW51_26425	COG1511	domain protein
EXW51_26430	COG0583	DNA-binding transcription factor activity
EXW51_26435	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW51_26440	COG1271	oxidase subunit
EXW51_26445	COG1294	oxidase, subunit
EXW51_26450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW51_26455	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW51_26460	COG1620	l-lactate permease
EXW51_26470	COG2389	metal-binding protein
EXW51_26480	COG1368	sulfuric ester hydrolase activity
EXW51_26490	COG0791	NLP P60 protein
EXW51_26490	COG1388	LysM domain
EXW51_26495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW51_26505	COG1215	transferase activity, transferring glycosyl groups
EXW51_26510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW51_26520	COG1388	LysM domain
EXW51_26520	COG3584	3D domain protein
EXW51_26545	COG4715	Zinc finger, swim domain protein
EXW51_26550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW51_26595	COG0577	efflux transmembrane transporter activity
EXW51_26600	COG1136	(ABC) transporter
EXW51_26635	COG3850	Histidine kinase
EXW51_26635	COG5002	protein histidine kinase activity
EXW51_26640	COG0745	RESPONSE REGULATOR receiver
EXW51_26660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW51_26665	COG1134	teichoic acid transport
EXW51_26670	COG1682	transport, permease protein
EXW51_26675	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW51_26680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW51_26690	COG0438	transferase activity, transferring glycosyl groups
EXW51_26695	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW51_26700	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW51_26705	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EXW51_26715	COG1609	Transcriptional regulator
EXW51_26720	COG0726	polysaccharide deacetylase
EXW51_26735	COG0739	heme binding
EXW51_26750	COG3279	Response regulator of the LytR AlgR family
EXW51_26755	COG2385	sporulation resulting in formation of a cellular spore
EXW51_26770	COG4836	Membrane
EXW51_26775	COG1007	ATP synthesis coupled electron transport
EXW51_26780	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW51_26785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW51_26790	COG0713	ATP synthesis coupled electron transport
EXW51_26795	COG0839	Belongs to the complex I subunit 6 family
EXW51_26805	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW51_26810	COG0649	NAD binding
EXW51_26815	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW51_26820	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW51_26825	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW51_26830	COG3300	MHYT domain
EXW51_26830	COG5001	Diguanylate cyclase
EXW51_26845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW51_26850	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW51_26855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW51_26860	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW51_26865	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW51_26870	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW51_26880	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW51_26905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW51_26915	COG0698	ribose 5-phosphate isomerase
EXW51_26925	COG2190	(PTS) system
EXW51_26930	COG2259	Doxx family
EXW51_26935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW51_26945	COG1971	Probably functions as a manganese efflux pump
EXW51_26950	COG0009	L-threonylcarbamoyladenylate synthase
EXW51_26965	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW51_26970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW51_26975	COG1435	thymidine kinase activity
EXW51_26985	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW51_26990	COG1494	fructose-1,6-bisphosphatase
EXW51_27010	COG4821	SIS domain
EXW51_27015	COG0504	CTP synthase activity
EXW51_27020	COG3343	RNA polymerase activity
EXW51_27030	COG1960	acyl-CoA dehydrogenase activity
EXW51_27035	COG1960	acyl-CoA dehydrogenase activity
EXW51_27040	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW51_27045	COG0183	Belongs to the thiolase family
EXW51_27050	COG0247	lactate metabolic process
EXW51_27050	COG2181	nitrate reductase activity
EXW51_27055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW51_27060	COG4294	response to UV
EXW51_27065	COG5001	Diguanylate cyclase
EXW51_27065	COG3300	MHYT domain
EXW51_27080	COG3227	Zinc metalloprotease (Elastase)
EXW51_27085	COG2197	response regulator
EXW51_27090	COG4585	Histidine kinase
EXW51_27095	COG0842	Transport permease protein
EXW51_27100	COG1131	(ABC) transporter
EXW51_27105	COG0024	Methionine aminopeptidase
EXW51_27115	COG2234	aminopeptidase activity
EXW51_27135	COG4506	Protein conserved in bacteria
EXW51_27140	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW51_27155	COG0010	Belongs to the arginase family
EXW51_27160	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW51_27165	COG2814	Major facilitator Superfamily
EXW51_27170	COG0789	Transcriptional regulator
EXW51_27175	COG0584	glycerophosphoryl diester phosphodiesterase
EXW51_27180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW51_27190	COG1994	Peptidase M50
EXW51_27200	COG1078	dGTPase activity
EXW51_27205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW51_27210	COG1120	ATPase activity
EXW51_27215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW51_27220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW51_27225	COG4844	belongs to the
EXW51_27240	COG0280	phosphate acetyltransferase
EXW51_27245	COG3253	May function as heme-dependent peroxidase
EXW51_27255	COG3773	Cell wall hydrolase
EXW51_27265	COG2363	Small membrane protein
EXW51_27280	COG2233	PERMEase
EXW51_27285	COG0561	phosphatase activity
EXW51_27290	COG2814	Major facilitator Superfamily
EXW51_27295	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW51_27300	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW51_27305	COG1131	(ABC) transporter
EXW51_27310	COG2755	lipolytic protein G-D-S-L family
EXW51_27315	COG1609	Transcriptional regulator
EXW51_27325	COG0460	homoserine dehydrogenase
EXW51_27330	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW51_27335	COG2873	o-acetylhomoserine
EXW51_27350	COG2197	response regulator
EXW51_27355	COG2203	Gaf domain
EXW51_27355	COG4585	Histidine kinase
EXW51_27360	COG0351	phosphomethylpyrimidine kinase
EXW51_27365	COG3706	GGDEF domain
EXW51_27370	COG2879	small protein
EXW51_27375	COG1966	Carbon starvation protein
EXW51_27380	COG3279	Response regulator of the LytR AlgR family
EXW51_27385	COG0477	Major facilitator Superfamily
EXW51_27415	COG0840	transmembrane signaling receptor activity
EXW51_27425	COG1607	acyl-coa hydrolase
EXW51_27430	COG1216	Glycosyl transferase, family 2
EXW51_27440	COG1216	Glycosyl transferase, family 2
EXW51_27450	COG4485	Bacterial membrane protein, YfhO
EXW51_27455	COG0463	Glycosyl transferase, family 2
EXW51_27465	COG1309	transcriptional regulator
EXW51_27470	COG0488	(ABC) transporter
EXW51_27475	COG1309	transcriptional regulator
EXW51_27480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW51_27485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW51_27485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW51_27490	COG0628	permease
EXW51_27500	COG1380	Effector of murein hydrolase LrgA
EXW51_27505	COG3279	Response regulator of the LytR AlgR family
EXW51_27510	COG3275	phosphorelay sensor kinase activity
EXW51_27515	COG2814	Major facilitator Superfamily
EXW51_27520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW51_27525	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW51_27535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW51_27570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW51_27575	COG1272	protein, Hemolysin III
EXW51_27600	COG1164	Oligoendopeptidase f
EXW51_27610	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW51_27620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW51_27625	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW51_27630	COG4853	Protein conserved in bacteria
EXW51_27640	COG5002	protein histidine kinase activity
EXW51_27645	COG0745	RESPONSE REGULATOR receiver
EXW51_27675	COG0305	Participates in initiation and elongation during chromosome replication
EXW51_27680	COG0359	binds to the 23S rRNA
EXW51_27685	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW51_27690	COG4241	membrane
EXW51_27700	COG0629	single-stranded DNA binding
EXW51_27705	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW51_27710	COG0012	GTP binding
EXW51_27715	COG4481	Protein conserved in bacteria
EXW51_27720	COG0668	transmembrane transport
EXW51_27730	COG1475	DNA binding
EXW51_27735	COG1192	Involved in chromosome partitioning
EXW51_27740	COG1475	DNA binding
EXW51_27745	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW51_27750	COG0445	tRNA wobble uridine modification
EXW51_27755	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW51_27760	COG1847	R3H domain protein
EXW51_27765	COG0706	membrane insertase activity
EXW51_27770	COG0594	ribonuclease P activity
EXW51_27775	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW51_27790	COG1454	alcohol dehydrogenase
EXW51_27790	COG1012	belongs to the aldehyde dehydrogenase family
EXW51_27800	COG0535	radical SAM domain protein
EXW51_27810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW51_27810	COG1328	CTP reductase activity
EXW51_27825	COG0426	domain, Protein
EXW51_27830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW51_27835	COG1773	rubredoxin
EXW51_27845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW51_27860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW51_27865	COG2116	formate transmembrane transporter activity
EXW51_27880	COG0531	amino acid
EXW51_27895	COG0531	amino acid
EXW51_27925	COG2070	2-Nitropropane dioxygenase
EXW51_27935	COG0823	Involved in the tonB-independent uptake of proteins
EXW51_27955	COG3979	chitinase
EXW51_27965	COG3829	transcription factor binding
EXW51_27965	COG3290	protein histidine kinase activity
EXW51_27970	COG3604	Transcriptional regulator
EXW51_27980	COG2376	Dihydroxyacetone kinase
EXW51_27995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW51_28000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW51_28010	COG0517	IMP dehydrogenase activity
EXW51_28010	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EXW51_28015	COG1486	melibiose metabolic process
EXW51_28025	COG3715	PTS system
EXW51_28030	COG3716	PTS system mannose fructose sorbose family IID component
EXW51_28075	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW51_28075	COG0456	acetyltransferase
EXW51_28085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW51_28090	COG1621	beta-fructofuranosidase activity
EXW51_28095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW51_28095	COG1263	PTS System
EXW51_28100	COG1609	Transcriptional regulator
EXW51_28125	COG3842	ATPase activity
EXW51_28130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW51_28135	COG0395	ABC-type sugar transport system, permease component
EXW51_28140	COG1175	transmembrane transport
EXW51_28145	COG1653	transport
EXW51_28150	COG1609	Transcriptional regulator
EXW51_28160	COG1554	hydrolase, family 65, central catalytic
EXW51_28190	COG3754	Rhamnan synthesis protein F
EXW51_28195	COG1131	(ABC) transporter
EXW51_28200	COG0842	Transport permease protein
EXW51_28215	COG1028	Short-chain dehydrogenase reductase Sdr
EXW51_28225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW51_28240	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW51_28245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW51_28265	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW51_28280	COG1131	(ABC) transporter
EXW51_28295	COG1132	(ABC) transporter
EXW51_28315	COG1482	cell wall glycoprotein biosynthetic process
EXW51_28320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW51_28320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW51_28320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW51_28325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW51_28325	COG3711	transcriptional antiterminator
EXW51_28335	COG0584	glycerophosphoryl diester phosphodiesterase
EXW51_28395	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW51_28445	COG0659	secondary active sulfate transmembrane transporter activity
EXW51_28460	COG1923	regulation of RNA biosynthetic process
EXW51_28475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW51_28480	COG1733	regulation of RNA biosynthetic process
EXW51_28515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW51_28555	COG0582	viral genome integration into host DNA
EXW51_28565	COG1164	Oligoendopeptidase f
EXW51_28580	COG1923	regulation of RNA biosynthetic process
EXW51_28650	COG0791	NLP P60 protein
EXW51_28650	COG3883	PFAM NLP P60 protein
EXW51_28705	COG5002	protein histidine kinase activity
EXW51_28745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW51_28765	COG0697	spore germination
EXW51_28770	COG0814	amino acid
EXW51_28805	COG1674	ftsk spoiiie
EXW51_28815	COG0741	lytic transglycosylase activity
EXW51_28820	COG5002	protein histidine kinase activity
EXW51_28825	COG0745	RESPONSE REGULATOR receiver
EXW51_28835	COG0577	efflux transmembrane transporter activity
EXW51_28840	COG1136	(ABC) transporter
EXW51_28875	COG1404	Belongs to the peptidase S8 family
EXW51_28930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW51_28935	COG5002	protein histidine kinase activity
EXW51_28940	COG0745	RESPONSE REGULATOR receiver
EXW51_29050	COG0741	lytic transglycosylase activity
EXW51_29050	COG0739	heme binding
EXW51_29050	COG1196	nuclear chromosome segregation
EXW51_29220	COG1609	Transcriptional regulator
EXW51_29225	COG2814	Major facilitator Superfamily
EXW51_29235	COG0673	inositol 2-dehydrogenase activity
EXW51_29260	COG1609	Transcriptional regulator
EXW51_29270	COG3718	enzyme involved in inositol metabolism
EXW51_29280	COG2222	sugar isomerase
EXW51_29290	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW51_29295	COG3715	PTS system
EXW51_29300	COG3716	PTS system mannose fructose sorbose family IID component
EXW51_29305	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW51_29305	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW51_29320	COG3684	Belongs to the aldolase LacD family
EXW51_29325	COG2188	Transcriptional regulator
EXW51_29350	COG2312	Erythromycin esterase
EXW51_29380	COG2267	carboxylic ester hydrolase activity
EXW51_29410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW51_29415	COG1595	DNA-templated transcription, initiation
EXW51_29450	COG1846	Transcriptional regulator
EXW51_29470	COG0745	RESPONSE REGULATOR receiver
EXW51_29475	COG5002	protein histidine kinase activity
EXW51_29570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW51_29570	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW51_29580	COG0776	regulation of translation
EXW51_29595	COG0577	efflux transmembrane transporter activity
EXW51_29600	COG1136	(ABC) transporter
EXW51_29605	COG0745	RESPONSE REGULATOR receiver
EXW51_29695	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW51_29720	COG0531	amino acid
EXW51_29725	COG2076	Multidrug Resistance protein
EXW51_29730	COG2076	Multidrug Resistance protein
EXW51_29770	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW51_29775	COG1760	l-serine dehydratase
EXW51_29780	COG1760	l-serine dehydratase
EXW51_29785	COG0814	amino acid
EXW51_29795	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW51_29805	COG0737	Belongs to the 5'-nucleotidase family
EXW51_29810	COG1073	alpha beta
EXW51_29815	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW51_29820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW51_29825	COG0772	Belongs to the SEDS family
EXW51_29830	COG2239	Acts as a magnesium transporter
EXW51_29840	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW51_29860	COG4974	Belongs to the 'phage' integrase family
EXW51_29890	COG0658	competence protein
EXW51_29890	COG2333	competence protein COMEC
EXW51_29925	COG2814	Major facilitator Superfamily
EXW51_29950	COG3655	Transcriptional regulator
EXW51_29990	COG0546	phosphoglycolate phosphatase activity
EXW51_29995	COG1349	DNA-binding transcription factor activity
EXW51_30035	COG2040	homocysteine
EXW51_30040	COG0833	amino acid
EXW51_30045	COG0697	spore germination
EXW51_30060	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW51_30070	COG2239	Acts as a magnesium transporter
EXW51_30080	COG0657	acetylesterase activity
EXW51_30080	COG2755	lipolytic protein G-D-S-L family
EXW51_30100	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW51_30110	COG2211	Major facilitator Superfamily
EXW51_30130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW51_30165	COG2373	Large extracellular alpha-helical protein
EXW51_30195	COG0789	Transcriptional regulator
EXW51_30260	COG0789	Transcriptional regulator
EXW51_30285	COG1329	Transcriptional regulator
EXW51_30305	COG0384	phenazine biosynthesis protein PhzF
EXW51_30365	COG0367	asparagine synthase
EXW51_30405	COG3711	transcriptional antiterminator
EXW51_30410	COG0823	Involved in the tonB-independent uptake of proteins
EXW51_30425	COG1114	Component of the transport system for branched-chain amino acids
EXW51_30480	COG0577	efflux transmembrane transporter activity
EXW51_30485	COG1136	(ABC) transporter
EXW51_30510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW51_30515	COG0577	efflux transmembrane transporter activity
EXW51_30520	COG1136	(ABC) transporter
EXW51_30530	COG0745	RESPONSE REGULATOR receiver
EXW51_30535	COG3850	Histidine kinase
EXW51_30535	COG5002	protein histidine kinase activity
EXW51_30555	COG1695	Transcriptional regulator
EXW51_30570	COG0456	acetyltransferase
EXW51_30660	COG3883	PFAM NLP P60 protein
EXW51_30660	COG0791	NLP P60 protein
EXW51_30780	COG2186	Transcriptional regulator