locus-tag	class	description
EXW28_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW28_00010	COG0592	DNA-directed DNA polymerase activity
EXW28_00015	COG2501	S4 domain
EXW28_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW28_00025	COG0187	DNA topoisomerase II activity
EXW28_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW28_00065	COG0517	IMP dehydrogenase activity
EXW28_00065	COG0516	GMP reductase activity
EXW28_00070	COG1686	Belongs to the peptidase S11 family
EXW28_00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW28_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW28_00100	COG1428	Deoxynucleoside kinase
EXW28_00105	COG1428	Deoxynucleoside kinase
EXW28_00110	COG1335	isochorismatase
EXW28_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW28_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW28_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW28_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW28_00180	COG1982	Orn Lys Arg decarboxylase major
EXW28_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW28_00190	COG0470	DNA polymerase III
EXW28_00195	COG1774	PSP1 C-terminal conserved region
EXW28_00200	COG4467	Involved in initiation control of chromosome replication
EXW28_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW28_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW28_00220	COG2002	toxin-antitoxin pair type II binding
EXW28_00230	COG0084	hydrolase, TatD family'
EXW28_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW28_00250	COG4466	Protein conserved in bacteria
EXW28_00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW28_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW28_00270	COG0251	oxidation-reduction process
EXW28_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW28_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW28_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW28_00305	COG2002	toxin-antitoxin pair type II binding
EXW28_00310	COG2244	polysaccharide biosynthetic process
EXW28_00315	COG3956	TIGRFAM MazG family protein
EXW28_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW28_00340	COG1098	S1 RNA binding domain
EXW28_00355	COG2208	phosphoserine phosphatase activity
EXW28_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW28_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW28_00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW28_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW28_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW28_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW28_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW28_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW28_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW28_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW28_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW28_00420	COG1396	sequence-specific DNA binding
EXW28_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW28_00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW28_00520	COG3880	PFAM UvrB UvrC protein
EXW28_00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW28_00530	COG0542	response to heat
EXW28_00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW28_00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW28_00545	COG4956	integral membrane protein (PIN domain superfamily)
EXW28_00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW28_00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW28_00565	COG1045	serine acetyltransferase
EXW28_00570	COG0215	cysteine-tRNA ligase activity
EXW28_00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW28_00585	COG3688	RNA-binding protein containing a PIN domain
EXW28_00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW28_00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW28_00605	COG0250	Participates in transcription elongation, termination and antitermination
EXW28_00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW28_00615	COG0081	regulation of translation
EXW28_00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW28_00625	COG0222	ribosome binding
EXW28_00630	COG2813	Specifically methylates the guanine in position
EXW28_00635	COG0085	RNA polymerase activity
EXW28_00640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW28_00645	COG1358	cellular component organization or biogenesis
EXW28_00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW28_00660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW28_00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW28_00670	COG0051	transcription antitermination factor activity, RNA binding
EXW28_00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW28_00680	COG0088	Forms part of the polypeptide exit tunnel
EXW28_00685	COG0089	rRNA binding
EXW28_00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW28_00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW28_00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW28_00715	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW28_00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW28_00730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW28_00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW28_00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW28_00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW28_00765	COG1841	ribosomal large subunit assembly
EXW28_00770	COG0200	Binds to the 23S rRNA
EXW28_00775	COG0201	protein transport
EXW28_00780	COG0563	adenylate kinase activity
EXW28_00785	COG0024	Methionine aminopeptidase
EXW28_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW28_00800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW28_00805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW28_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW28_00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW28_00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW28_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW28_00860	COG0489	protein tyrosine kinase activity
EXW28_00870	COG2194	sulfuric ester hydrolase activity
EXW28_00875	COG0726	polysaccharide deacetylase
EXW28_00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW28_00960	COG4856	YbbR-like protein
EXW28_00965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW28_01010	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_01015	COG2011	ABC-type metal ion transport system permease component
EXW28_01025	COG1464	Belongs to the NlpA lipoprotein family
EXW28_01040	COG0277	FAD linked oxidase domain protein
EXW28_01045	COG2271	Major facilitator Superfamily
EXW28_01055	COG2814	Major facilitator Superfamily
EXW28_01075	COG0601	transmembrane transport
EXW28_01080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW28_01085	COG0444	Belongs to the ABC transporter superfamily
EXW28_01090	COG4608	Belongs to the ABC transporter superfamily
EXW28_01095	COG4166	transmembrane transport
EXW28_01105	COG2207	Transcriptional regulator
EXW28_01120	COG4166	transmembrane transport
EXW28_01125	COG4166	transmembrane transport
EXW28_01130	COG0656	L-ascorbic acid biosynthetic process
EXW28_01135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW28_01150	COG4149	molybdate abc transporter
EXW28_01155	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW28_01160	COG1910	domain protein
EXW28_01175	COG0697	spore germination
EXW28_01190	COG0204	Acyl-transferase
EXW28_01200	COG1609	Transcriptional regulator
EXW28_01210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW28_01225	COG5298	Protein conserved in bacteria
EXW28_01250	COG0488	(ABC) transporter
EXW28_01260	COG0747	negative chemotaxis
EXW28_01270	COG0601	transmembrane transport
EXW28_01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW28_01280	COG0444	Belongs to the ABC transporter superfamily
EXW28_01285	COG4608	Belongs to the ABC transporter superfamily
EXW28_01290	COG0561	phosphatase activity
EXW28_01320	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW28_01325	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW28_01335	COG0531	amino acid
EXW28_01340	COG2814	Major facilitator Superfamily
EXW28_01350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW28_01360	COG4294	response to UV
EXW28_01365	COG0705	Rhomboid family
EXW28_01370	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW28_01375	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW28_01380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW28_01385	COG0864	Transcriptional regulator
EXW28_01390	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW28_01395	COG2183	response to ionizing radiation
EXW28_01495	COG0802	atpase or kinase
EXW28_01500	COG1214	PFAM Peptidase M22, glycoprotease
EXW28_01505	COG0456	acetyltransferase
EXW28_01515	COG0488	(ABC) transporter
EXW28_01520	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW28_01530	COG1266	CAAX protease self-immunity
EXW28_01535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW28_01540	COG0459	protein refolding
EXW28_01545	COG0519	Catalyzes the synthesis of GMP from XMP
EXW28_01545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW28_01550	COG2252	PERMEase
EXW28_01560	COG5002	protein histidine kinase activity
EXW28_01585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW28_01610	COG0693	protein deglycase activity
EXW28_01650	COG4187	Peptidase family M20/M25/M40
EXW28_01670	COG2205	protein histidine kinase activity
EXW28_01675	COG0745	RESPONSE REGULATOR receiver
EXW28_01700	COG0697	spore germination
EXW28_01725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW28_01730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW28_01735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW28_01740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW28_01745	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW28_01750	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW28_01755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW28_01760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW28_01765	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW28_01770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW28_01775	COG0138	bifunctional purine biosynthesis protein purh
EXW28_01785	COG0151	Belongs to the GarS family
EXW28_01810	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW28_01815	COG0210	DNA helicase
EXW28_01820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW28_01825	COG4851	CamS sex pheromone cAM373 precursor
EXW28_01835	COG1012	belongs to the aldehyde dehydrogenase family
EXW28_01840	COG1335	isochorismatase
EXW28_01850	COG2011	ABC-type metal ion transport system permease component
EXW28_01855	COG1464	Belongs to the NlpA lipoprotein family
EXW28_01870	COG0003	Pfam Anion-transporting ATPase
EXW28_01875	COG1846	Transcriptional regulator
EXW28_01880	COG4682	membrane
EXW28_01890	COG0154	amidase activity
EXW28_01895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW28_01900	COG1597	lipid kinase activity
EXW28_01905	COG0546	phosphoglycolate phosphatase activity
EXW28_01910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW28_01920	COG1012	belongs to the aldehyde dehydrogenase family
EXW28_01925	COG2076	Multidrug Resistance protein
EXW28_01930	COG2309	aminopeptidase activity
EXW28_01945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW28_01955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW28_01960	COG5002	protein histidine kinase activity
EXW28_01965	COG4807	Protein conserved in bacteria
EXW28_01990	COG1757	Na H antiporter
EXW28_01995	COG1473	amidohydrolase
EXW28_02015	COG0450	alkyl hydroperoxide reductase
EXW28_02025	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW28_02035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW28_02040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW28_02045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW28_02050	COG0492	ferredoxin-NADP+ reductase activity
EXW28_02060	COG0166	Belongs to the GPI family
EXW28_02085	COG5002	protein histidine kinase activity
EXW28_02105	COG3541	Predicted nucleotidyltransferase
EXW28_02110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW28_02110	COG0723	plastoquinol--plastocyanin reductase activity
EXW28_02120	COG0765	amino acid transport
EXW28_02125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW28_02135	COG0840	transmembrane signaling receptor activity
EXW28_02160	COG0549	Belongs to the carbamate kinase family
EXW28_02175	COG0277	FAD linked oxidase domain protein
EXW28_02180	COG0366	Alpha amylase catalytic
EXW28_02185	COG2190	(PTS) system
EXW28_02185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW28_02185	COG1263	PTS System
EXW28_02205	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW28_02215	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW28_02235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW28_02240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW28_02245	COG1116	anion transmembrane transporter activity
EXW28_02250	COG0488	(ABC) transporter
EXW28_02295	COG2270	Major facilitator Superfamily
EXW28_02325	COG2310	stress, protein
EXW28_02330	COG2310	stress, protein
EXW28_02335	COG2310	stress, protein
EXW28_02340	COG0861	Integral membrane protein TerC family
EXW28_02350	COG3853	Toxic anion resistance protein (TelA)
EXW28_02360	COG4840	Belongs to the UPF0435 family
EXW28_02375	COG1295	ribonuclease BN
EXW28_02380	COG2217	Heavy metal translocating P-type atpase
EXW28_02385	COG0697	spore germination
EXW28_02410	COG0586	Pfam SNARE associated Golgi protein
EXW28_02425	COG3871	stress protein (general stress protein 26)
EXW28_02430	COG0387	Pfam Sodium calcium exchanger
EXW28_02440	COG0535	radical SAM domain protein
EXW28_02460	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW28_02480	COG3829	transcription factor binding
EXW28_02490	COG0833	amino acid
EXW28_02495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW28_02515	COG2066	Belongs to the glutaminase family
EXW28_02525	COG1263	PTS System
EXW28_02525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW28_02530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW28_02545	COG1216	Glycosyl transferase, family 2
EXW28_02555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW28_02555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW28_02560	COG0463	Glycosyl transferase, family 2
EXW28_02575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW28_02580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW28_02595	COG1228	amidohydrolase
EXW28_02600	COG1090	epimerase
EXW28_02605	COG2137	regulation of response to DNA damage stimulus
EXW28_02630	COG1988	membrane-bound metal-dependent
EXW28_02635	COG1194	a g-specific adenine glycosylase
EXW28_02655	COG3557	Belongs to the UPF0374 family
EXW28_02660	COG1132	(ABC) transporter
EXW28_02665	COG4129	membrane
EXW28_02675	COG0067	glutamate synthase
EXW28_02675	COG0069	glutamate synthase activity
EXW28_02675	COG0070	glutamate synthase
EXW28_02680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW28_02685	COG4555	ABC transporter
EXW28_02705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW28_02710	COG0735	belongs to the Fur family
EXW28_02830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW28_02835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW28_02855	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW28_02865	COG2766	serine protein kinase
EXW28_02870	COG2718	Belongs to the UPF0229 family
EXW28_02875	COG0494	nUDIX hydrolase
EXW28_02880	COG0673	inositol 2-dehydrogenase activity
EXW28_02885	COG2091	lysine biosynthetic process via aminoadipic acid
EXW28_02945	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW28_02950	COG2268	Band 7 protein
EXW28_02965	COG3290	protein histidine kinase activity
EXW28_02970	COG4565	transcriptional regulatory protein
EXW28_02975	COG2851	Citrate transporter
EXW28_03000	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW28_03005	COG3842	ATPase activity
EXW28_03010	COG1175	transmembrane transport
EXW28_03015	COG0395	ABC-type sugar transport system, permease component
EXW28_03025	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW28_03030	COG0745	RESPONSE REGULATOR receiver
EXW28_03035	COG5002	protein histidine kinase activity
EXW28_03045	COG4990	cell redox homeostasis
EXW28_03055	COG3290	protein histidine kinase activity
EXW28_03060	COG4565	transcriptional regulatory protein
EXW28_03065	COG3493	citrate carrier protein
EXW28_03070	COG0281	malic enzyme
EXW28_03080	COG0697	spore germination
EXW28_03085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW28_03095	COG5002	protein histidine kinase activity
EXW28_03100	COG0745	RESPONSE REGULATOR receiver
EXW28_03105	COG0456	acetyltransferase
EXW28_03110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW28_03115	COG3383	formate dehydrogenase (NAD+) activity
EXW28_03120	COG2427	Protein of unknown function (DUF1641)
EXW28_03135	COG0531	amino acid
EXW28_03145	COG0640	Transcriptional regulator
EXW28_03150	COG2217	Heavy metal translocating P-type atpase
EXW28_03155	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW28_03165	COG3227	Zinc metalloprotease (Elastase)
EXW28_03185	COG2720	vancomycin resistance protein
EXW28_03190	COG1316	TRANSCRIPTIONal
EXW28_03195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW28_03200	COG0346	lactoylglutathione lyase activity
EXW28_03205	COG1253	flavin adenine dinucleotide binding
EXW28_03210	COG1027	Aspartate ammonia-lyase
EXW28_03215	COG1620	l-lactate permease
EXW28_03220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW28_03240	COG3104	oligopeptide transport
EXW28_03245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW28_03250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW28_03255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW28_03270	COG0156	8-amino-7-oxononanoate synthase activity
EXW28_03275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW28_03285	COG4548	von Willebrand factor, type A
EXW28_03290	COG0714	Associated with various cellular activities
EXW28_03310	COG0531	amino acid
EXW28_03315	COG2188	Transcriptional regulator
EXW28_03320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW28_03320	COG1263	PTS System
EXW28_03325	COG0366	Alpha amylase catalytic
EXW28_03355	COG1115	amino acid carrier protein
EXW28_03360	COG1126	abc transporter atp-binding protein
EXW28_03365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW28_03370	COG0765	amino acid transport
EXW28_03375	COG0765	amino acid transport
EXW28_03380	COG0833	amino acid
EXW28_03405	COG2378	regulation of single-species biofilm formation
EXW28_03410	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW28_03415	COG5002	protein histidine kinase activity
EXW28_03430	COG0659	secondary active sulfate transmembrane transporter activity
EXW28_03455	COG0601	transmembrane transport
EXW28_03460	COG4608	Belongs to the ABC transporter superfamily
EXW28_03470	COG2271	Major facilitator Superfamily
EXW28_03475	COG1846	Transcriptional regulator
EXW28_03480	COG0477	Major facilitator Superfamily
EXW28_03485	COG1609	Transcriptional regulator
EXW28_03490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW28_03495	COG1869	D-ribose catabolic process
EXW28_03505	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW28_03510	COG1879	ABC-type sugar transport system periplasmic component
EXW28_03540	COG1063	alcohol dehydrogenase
EXW28_03585	COG0840	transmembrane signaling receptor activity
EXW28_03590	COG3584	3D domain protein
EXW28_03590	COG3583	domain protein
EXW28_03595	COG1476	TRANSCRIPTIONal
EXW28_03615	COG3104	oligopeptide transport
EXW28_03620	COG1114	Component of the transport system for branched-chain amino acids
EXW28_03635	COG1113	amino acid transport
EXW28_03640	COG2252	PERMEase
EXW28_03645	COG3620	sequence-specific DNA binding
EXW28_03665	COG0569	domain protein
EXW28_03665	COG0475	glutathione-regulated potassium exporter activity
EXW28_03680	COG1845	cytochrome c oxidase, subunit III
EXW28_03685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW28_03695	COG0833	amino acid
EXW28_03700	COG4990	cell redox homeostasis
EXW28_03715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW28_03720	COG0697	spore germination
EXW28_03725	COG0531	amino acid
EXW28_03735	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW28_03740	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW28_03750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW28_03755	COG0573	inorganic phosphate transmembrane transporter activity
EXW28_03760	COG0581	inorganic phosphate transmembrane transporter activity
EXW28_03770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW28_03890	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW28_03910	COG4991	sh3 domain protein
EXW28_03910	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW28_03910	COG3103	Sh3 type 3 domain protein
EXW28_03915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW28_03920	COG1116	anion transmembrane transporter activity
EXW28_03925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW28_03930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW28_03935	COG0352	thiamine-phosphate diphosphorylase activity
EXW28_03940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW28_03945	COG2104	thiamine diphosphate biosynthetic process
EXW28_03950	COG2022	thiamine diphosphate biosynthetic process
EXW28_03955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW28_03960	COG0351	phosphomethylpyrimidine kinase
EXW28_03985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW28_03990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW28_03995	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW28_04000	COG2205	protein histidine kinase activity
EXW28_04005	COG2814	Major facilitator Superfamily
EXW28_04010	COG1846	Transcriptional regulator
EXW28_04030	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW28_04035	COG1129	ABC transporter
EXW28_04040	COG1879	ABC-type sugar transport system periplasmic component
EXW28_04045	COG2252	PERMEase
EXW28_04050	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_04115	COG0778	Nitroreductase
EXW28_04120	COG2719	SpoVR family
EXW28_04145	COG1937	Protein conserved in bacteria
EXW28_04150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW28_04150	COG0425	Belongs to the sulfur carrier protein TusA family
EXW28_04155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW28_04155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW28_04160	COG0425	Belongs to the sulfur carrier protein TusA family
EXW28_04165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW28_04165	COG0425	Belongs to the sulfur carrier protein TusA family
EXW28_04170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW28_04175	COG2210	Belongs to the sulfur carrier protein TusA family
EXW28_04180	COG0730	response to heat
EXW28_04190	COG1316	TRANSCRIPTIONal
EXW28_04210	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW28_04215	COG0604	alcohol dehydrogenase
EXW28_04220	COG2814	Major facilitator Superfamily
EXW28_04235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW28_04235	COG3711	transcriptional antiterminator
EXW28_04240	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW28_04245	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW28_04270	COG3584	3D domain protein
EXW28_04270	COG1388	LysM domain
EXW28_04275	COG0577	efflux transmembrane transporter activity
EXW28_04280	COG1136	(ABC) transporter
EXW28_04290	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW28_04305	COG1114	Component of the transport system for branched-chain amino acids
EXW28_04310	COG3546	catalase activity
EXW28_04340	COG0586	Pfam SNARE associated Golgi protein
EXW28_04370	COG0531	amino acid
EXW28_04375	COG0475	glutathione-regulated potassium exporter activity
EXW28_04385	COG1737	Transcriptional regulator
EXW28_04395	COG1263	PTS System
EXW28_04395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW28_04405	COG2259	Doxx family
EXW28_04430	COG1522	sequence-specific DNA binding
EXW28_04455	COG2076	Multidrug Resistance protein
EXW28_04460	COG1309	transcriptional regulator
EXW28_04465	COG2814	Major facilitator Superfamily
EXW28_04470	COG1733	regulation of RNA biosynthetic process
EXW28_04485	COG4533	DNA binding
EXW28_04490	COG2211	Major facilitator Superfamily
EXW28_04510	COG0531	amino acid
EXW28_04515	COG1012	belongs to the aldehyde dehydrogenase family
EXW28_04530	COG1132	(ABC) transporter
EXW28_04535	COG1132	(ABC) transporter
EXW28_04540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW28_04545	COG0765	amino acid transport
EXW28_04550	COG1126	abc transporter atp-binding protein
EXW28_04565	COG0189	ligase activity
EXW28_04575	COG4399	Belongs to the UPF0754 family
EXW28_04580	COG3679	Belongs to the UPF0342 family
EXW28_04595	COG0028	Belongs to the TPP enzyme family
EXW28_04600	COG3527	Alpha-acetolactate decarboxylase
EXW28_04605	COG0463	Glycosyl transferase, family 2
EXW28_04610	COG1216	Glycosyl transferase, family 2
EXW28_04615	COG2094	Belongs to the DNA glycosylase MPG family
EXW28_04620	COG0561	phosphatase activity
EXW28_04630	COG3409	Peptidoglycan-binding domain 1 protein
EXW28_04630	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW28_04635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW28_04640	COG0318	PFAM AMP-dependent synthetase and ligase
EXW28_04650	COG0659	secondary active sulfate transmembrane transporter activity
EXW28_04655	COG2244	polysaccharide biosynthetic process
EXW28_04675	COG1024	Enoyl-CoA hydratase
EXW28_04705	COG1363	Peptidase, m42
EXW28_04720	COG2318	DinB family
EXW28_04740	COG0579	oxidoreductase
EXW28_04765	COG0601	transmembrane transport
EXW28_04770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW28_04775	COG0444	Belongs to the ABC transporter superfamily
EXW28_04780	COG4608	Belongs to the ABC transporter superfamily
EXW28_04805	COG0477	Major facilitator Superfamily
EXW28_04810	COG3290	protein histidine kinase activity
EXW28_04815	COG4565	transcriptional regulatory protein
EXW28_04880	COG0305	Participates in initiation and elongation during chromosome replication
EXW28_04910	COG1842	Phage shock protein A
EXW28_04920	COG0477	Major facilitator Superfamily
EXW28_04970	COG2814	Major facilitator Superfamily
EXW28_04975	COG0640	Transcriptional regulator
EXW28_05000	COG2376	Dihydroxyacetone kinase
EXW28_05020	COG2376	Dihydroxyacetone kinase
EXW28_05035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW28_05050	COG0457	Tetratricopeptide repeat
EXW28_05060	COG2373	Large extracellular alpha-helical protein
EXW28_05080	COG2211	Major facilitator Superfamily
EXW28_05120	COG0825	malonyl-CoA metabolic process
EXW28_05145	COG2807	transmembrane transport
EXW28_05165	COG4585	Histidine kinase
EXW28_05170	COG2197	response regulator
EXW28_05200	COG0420	3'-5' exonuclease activity
EXW28_05205	COG4717	serine-type aminopeptidase activity
EXW28_05215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW28_05220	COG0346	lactoylglutathione lyase activity
EXW28_05225	COG0346	lactoylglutathione lyase activity
EXW28_05230	COG0457	Tetratricopeptide repeat
EXW28_05245	COG2267	carboxylic ester hydrolase activity
EXW28_05255	COG3620	sequence-specific DNA binding
EXW28_05260	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW28_05265	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW28_05270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW28_05275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW28_05280	COG1695	Transcriptional regulator
EXW28_05300	COG1595	DNA-templated transcription, initiation
EXW28_05315	COG3973	AAA domain
EXW28_05320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW28_05345	COG0537	adenosine 5'-monophosphoramidase activity
EXW28_05350	COG1131	(ABC) transporter
EXW28_05355	COG4473	ABC transporter
EXW28_05365	COG0247	lactate metabolic process
EXW28_05370	COG1139	Iron-sulfur cluster binding protein
EXW28_05375	COG1556	Lactate utilization protein
EXW28_05395	COG3402	PFAM membrane-flanked domain
EXW28_05400	COG3428	Bacterial PH domain
EXW28_05440	COG3402	PFAM membrane-flanked domain
EXW28_05445	COG3428	Bacterial PH domain
EXW28_05450	COG2329	Antibiotic biosynthesis monooxygenase
EXW28_05455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW28_05460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW28_05465	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW28_05470	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW28_05490	COG1309	transcriptional regulator
EXW28_05495	COG1511	domain protein
EXW28_05530	COG1609	Transcriptional regulator
EXW28_05540	COG1234	tRNA 3'-trailer cleavage
EXW28_05545	COG0095	Lipoate-protein ligase
EXW28_05555	COG0318	PFAM AMP-dependent synthetase and ligase
EXW28_05570	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW28_05580	COG4208	sulfate ABC transporter
EXW28_05590	COG3209	COG3209 Rhs family protein
EXW28_05655	COG1408	metallophosphoesterase
EXW28_05660	COG1078	dGTPase activity
EXW28_05675	COG1595	DNA-templated transcription, initiation
EXW28_05685	COG3708	Transcriptional regulator
EXW28_05685	COG2207	Transcriptional regulator
EXW28_05690	COG2205	protein histidine kinase activity
EXW28_05695	COG0745	RESPONSE REGULATOR receiver
EXW28_05715	COG0501	Belongs to the peptidase M48B family
EXW28_05720	COG0840	transmembrane signaling receptor activity
EXW28_05725	COG0697	spore germination
EXW28_05730	COG3693	PFAM glycoside hydrolase, family 10
EXW28_05735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW28_05740	COG2224	Isocitrate lyase
EXW28_05750	COG1278	Cold shock
EXW28_05770	COG4903	ComK protein
EXW28_05775	COG0398	Pfam SNARE associated Golgi protein
EXW28_05785	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW28_05790	COG1074	ATP-dependent DNA helicase activity
EXW28_05840	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW28_05865	COG0367	asparagine synthase
EXW28_05885	COG0753	catalase activity
EXW28_05890	COG0004	ammonium transporteR
EXW28_05900	COG1666	GTP binding
EXW28_05905	COG2996	Protein conserved in bacteria
EXW28_05920	COG1329	Transcriptional regulator
EXW28_05955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW28_05965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW28_05980	COG0561	phosphatase activity
EXW28_06000	COG2267	carboxylic ester hydrolase activity
EXW28_06015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW28_06020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW28_06025	COG5504	Zn-dependent protease
EXW28_06045	COG0180	Tryptophanyl-tRNA synthetase
EXW28_06060	COG4166	transmembrane transport
EXW28_06065	COG0601	transmembrane transport
EXW28_06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW28_06075	COG0444	Belongs to the ABC transporter superfamily
EXW28_06080	COG4608	Belongs to the ABC transporter superfamily
EXW28_06085	COG0534	Mate efflux family protein
EXW28_06090	COG4166	transmembrane transport
EXW28_06110	COG0861	Integral membrane protein TerC family
EXW28_06115	COG4862	establishment of competence for transformation
EXW28_06120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW28_06130	COG1164	Oligoendopeptidase f
EXW28_06140	COG2346	COG2346, Truncated hemoglobins
EXW28_06145	COG4116	CYTH
EXW28_06155	COG2357	RelA SpoT domain protein
EXW28_06165	COG0564	pseudouridine synthase activity
EXW28_06175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW28_06180	COG0772	Belongs to the SEDS family
EXW28_06185	COG1216	Glycosyl transferase, family 2
EXW28_06205	COG0463	Glycosyl transferase, family 2
EXW28_06205	COG0457	Tetratricopeptide repeat
EXW28_06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW28_06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW28_06285	COG2153	protein acetylation
EXW28_06290	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW28_06295	COG2382	esterase
EXW28_06320	COG5492	domain, Protein
EXW28_06325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW28_06340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW28_06340	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW28_06345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW28_06350	COG0134	indole-3-glycerol-phosphate synthase activity
EXW28_06355	COG0135	phosphoribosylanthranilate isomerase activity
EXW28_06360	COG0133	tryptophan synthase activity
EXW28_06365	COG0159	tryptophan synthase activity
EXW28_06375	COG1620	l-lactate permease
EXW28_06380	COG5634	Uncharacterized conserved protein (DUF2278)
EXW28_06440	COG2226	methyltransferase
EXW28_06460	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW28_06465	COG0567	Dehydrogenase, E1 component
EXW28_06470	COG1476	TRANSCRIPTIONal
EXW28_06495	COG4152	abc transporter atp-binding protein
EXW28_06500	COG1668	transmembrane transport
EXW28_06525	COG1686	Belongs to the peptidase S11 family
EXW28_06530	COG0681	Belongs to the peptidase S26 family
EXW28_06565	COG1012	belongs to the aldehyde dehydrogenase family
EXW28_06575	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW28_06580	COG1177	transmembrane transport
EXW28_06585	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW28_06595	COG2409	Drug exporters of the RND superfamily
EXW28_06605	COG0564	pseudouridine synthase activity
EXW28_06615	COG2340	Cysteine-rich secretory protein family
EXW28_06620	COG0247	lactate metabolic process
EXW28_06625	COG0277	FAD linked oxidase domain protein
EXW28_06630	COG3835	regulator
EXW28_06640	COG0745	RESPONSE REGULATOR receiver
EXW28_06645	COG5002	protein histidine kinase activity
EXW28_06650	COG2186	Transcriptional regulator
EXW28_06655	COG0247	lactate metabolic process
EXW28_06660	COG1139	Iron-sulfur cluster binding protein
EXW28_06665	COG1556	Lactate utilization protein
EXW28_06670	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW28_06680	COG2116	formate transmembrane transporter activity
EXW28_06685	COG0861	Integral membrane protein TerC family
EXW28_06690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW28_06700	COG2030	dehydratase
EXW28_06720	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_06725	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW28_06735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW28_06750	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW28_06755	COG3842	ATPase activity
EXW28_06770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW28_06780	COG1349	DNA-binding transcription factor activity
EXW28_06790	COG0235	Class ii aldolase
EXW28_06800	COG2861	carbohydrate metabolic process
EXW28_06810	COG3852	Histidine kinase
EXW28_06815	COG1846	Transcriptional regulator
EXW28_06825	COG2318	DinB family
EXW28_06830	COG5002	protein histidine kinase activity
EXW28_06835	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW28_06840	COG0720	synthase
EXW28_06850	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW28_06855	COG4873	Protein conserved in bacteria
EXW28_06865	COG0456	acetyltransferase
EXW28_06885	COG1780	Probably involved in ribonucleotide reductase function
EXW28_06900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW28_06905	COG0531	amino acid
EXW28_06910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW28_06925	COG2204	response regulator
EXW28_06930	COG1012	belongs to the aldehyde dehydrogenase family
EXW28_06940	COG1725	Transcriptional regulator
EXW28_06945	COG1131	(ABC) transporter
EXW28_06955	COG1131	(ABC) transporter
EXW28_06960	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW28_06965	COG1266	CAAX protease self-immunity
EXW28_06975	COG1522	sequence-specific DNA binding
EXW28_06985	COG1335	isochorismatase
EXW28_06995	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW28_07000	COG2070	2-Nitropropane dioxygenase
EXW28_07005	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW28_07010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW28_07015	COG1696	Membrane protein involved in D-alanine export
EXW28_07020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW28_07035	COG0716	FMN binding
EXW28_07060	COG0534	Mate efflux family protein
EXW28_07085	COG1846	Transcriptional regulator
EXW28_07095	COG1301	dicarboxylic acid transport
EXW28_07100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW28_07110	COG3874	Sporulation protein YtfJ
EXW28_07130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW28_07135	COG0028	Belongs to the TPP enzyme family
EXW28_07140	COG0440	acetolactate synthase activity
EXW28_07150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW28_07160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW28_07170	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW28_07175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW28_07185	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW28_07190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW28_07195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW28_07200	COG0107	imidazoleglycerol-phosphate synthase activity
EXW28_07210	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW28_07215	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW28_07230	COG1183	phosphatidylcholine synthase activity
EXW28_07235	COG1368	sulfuric ester hydrolase activity
EXW28_07245	COG0019	diaminopimelate decarboxylase activity
EXW28_07255	COG0175	sulfate reduction
EXW28_07260	COG2046	Belongs to the sulfate adenylyltransferase family
EXW28_07265	COG0529	Catalyzes the synthesis of activated sulfate
EXW28_07270	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW28_07290	COG1648	precorrin-2 dehydrogenase activity
EXW28_07295	COG0733	neurotransmitter:sodium symporter activity
EXW28_07315	COG1757	Na H antiporter
EXW28_07335	COG4758	membrane
EXW28_07340	COG4585	Histidine kinase
EXW28_07345	COG2197	response regulator
EXW28_07355	COG1114	Component of the transport system for branched-chain amino acids
EXW28_07365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW28_07410	COG0730	response to heat
EXW28_07415	COG0306	phosphate transporter
EXW28_07420	COG1392	Phosphate transport regulator
EXW28_07425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW28_07440	COG3852	Histidine kinase
EXW28_07445	COG1801	Protein of unknown function DUF72
EXW28_07455	COG0582	viral genome integration into host DNA
EXW28_07460	COG5002	protein histidine kinase activity
EXW28_07475	COG0392	lysyltransferase activity
EXW28_07475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW28_07490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW28_07495	COG1686	Belongs to the peptidase S11 family
EXW28_07500	COG2715	membrane protein required for spore maturation
EXW28_07505	COG0700	Nucleoside recognition
EXW28_07510	COG1187	pseudouridine synthase activity
EXW28_07520	COG1333	cytochrome c biogenesis protein
EXW28_07525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW28_07530	COG0745	RESPONSE REGULATOR receiver
EXW28_07535	COG5002	protein histidine kinase activity
EXW28_07540	COG2096	Adenosyltransferase
EXW28_07545	COG4942	peptidase
EXW28_07555	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW28_07560	COG1141	Ferredoxin
EXW28_07570	COG4955	Helix-turn-helix domain
EXW28_07575	COG0514	ATP-dependent DNA helicase (RecQ)
EXW28_07580	COG1266	CAAX protease self-immunity
EXW28_07590	COG1408	metallophosphoesterase
EXW28_07605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW28_07625	COG0492	ferredoxin-NADP+ reductase activity
EXW28_07630	COG0252	asparaginase activity
EXW28_07635	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW28_07645	COG1304	FMN binding
EXW28_07675	COG1160	GTP binding
EXW28_07680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW28_07700	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW28_07750	COG0302	gtp cyclohydrolase
EXW28_07755	COG0142	geranyltranstransferase activity
EXW28_07760	COG2226	methyltransferase
EXW28_07765	COG0142	geranyltranstransferase activity
EXW28_07780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW28_07790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW28_07795	COG0457	Tetratricopeptide repeat
EXW28_07800	COG5582	Belongs to the UPF0302 family
EXW28_07815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW28_07830	COG4347	Protein of unknown function (DUF1405)
EXW28_07845	COG2738	Putative neutral zinc metallopeptidase
EXW28_07855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW28_07860	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW28_07865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW28_07870	COG1803	Methylglyoxal synthase
EXW28_07875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW28_07880	COG0438	transferase activity, transferring glycosyl groups
EXW28_07885	COG0617	tRNA 3'-terminal CCA addition
EXW28_07895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW28_07900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW28_07910	COG1199	ATP-dependent helicase activity
EXW28_07910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW28_07930	COG3935	DnaD domain protein
EXW28_07935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW28_07945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW28_07945	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW28_07950	COG3331	DNA recombination
EXW28_07985	COG4474	Belongs to the UPF0398 family
EXW28_07990	COG3599	regulation of cell shape
EXW28_08000	COG0116	Belongs to the methyltransferase superfamily
EXW28_08010	COG1199	ATP-dependent helicase activity
EXW28_08015	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW28_08025	COG0024	Methionine aminopeptidase
EXW28_08035	COG2233	PERMEase
EXW28_08040	COG2311	Membrane
EXW28_08050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW28_08060	COG0456	acetyltransferase
EXW28_08110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW28_08125	COG0454	-acetyltransferase
EXW28_08145	COG0328	RNA-DNA hybrid ribonuclease activity
EXW28_08180	COG3403	YqcI/YcgG family
EXW28_08185	COG1280	lysine exporter protein (LysE YggA)
EXW28_08200	COG3162	membrane
EXW28_08205	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW28_08210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW28_08220	COG0475	glutathione-regulated potassium exporter activity
EXW28_08225	COG0789	Transcriptional regulator
EXW28_08225	COG4978	Transcriptional regulator
EXW28_08230	COG0534	Mate efflux family protein
EXW28_08235	COG2323	membrane
EXW28_08240	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW28_08265	COG2814	Major facilitator Superfamily
EXW28_08285	COG1923	regulation of RNA biosynthetic process
EXW28_08295	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW28_08300	COG1360	Flagellar Motor Protein
EXW28_08305	COG2201	protein-glutamate methylesterase activity
EXW28_08310	COG0643	Histidine kinase
EXW28_08310	COG2198	Histidine kinase
EXW28_08315	COG1776	CheC inhibitor of MCP methylation
EXW28_08315	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW28_08330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW28_08350	COG1256	bacterial-type flagellum assembly
EXW28_08355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW28_08375	COG1815	bacterial-type flagellum-dependent cell motility
EXW28_08380	COG1558	bacterial-type flagellum-dependent cell motility
EXW28_08390	COG1766	The M ring may be actively involved in energy transduction
EXW28_08395	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW28_08405	COG1157	protein secretion by the type III secretion system
EXW28_08425	COG1749	Flagellar hook protein flgE
EXW28_08440	COG0784	Response regulator, receiver
EXW28_08440	COG0835	chemotaxis
EXW28_08465	COG0861	Integral membrane protein TerC family
EXW28_08475	COG3383	formate dehydrogenase (NAD+) activity
EXW28_08480	COG2427	Protein of unknown function (DUF1641)
EXW28_08485	COG5609	conserved protein (DUF2294)
EXW28_08490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW28_08500	COG2116	formate transmembrane transporter activity
EXW28_08505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW28_08510	COG0303	'Molybdopterin
EXW28_08515	COG0314	molybdopterin synthase activity
EXW28_08520	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW28_08530	COG0489	protein tyrosine kinase activity
EXW28_08535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW28_08540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW28_08545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW28_08550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW28_08555	COG0741	lytic transglycosylase activity
EXW28_08565	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW28_08570	COG1776	CheC inhibitor of MCP methylation
EXW28_08570	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW28_08580	COG1338	Plays a role in the flagellum-specific transport system
EXW28_08585	COG1987	bacterial-type flagellum assembly
EXW28_08595	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW28_08600	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW28_08605	COG1419	protein localization to endoplasmic reticulum
EXW28_08610	COG4786	Flagellar basal body rod
EXW28_08625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW28_08660	COG2329	Antibiotic biosynthesis monooxygenase
EXW28_08675	COG2814	Major facilitator Superfamily
EXW28_08685	COG0583	DNA-binding transcription factor activity
EXW28_08690	COG3842	ATPase activity
EXW28_08740	COG0406	alpha-ribazole phosphatase activity
EXW28_08770	COG0367	asparagine synthase
EXW28_08800	COG1802	Transcriptional regulator
EXW28_08805	COG0697	spore germination
EXW28_08825	COG1216	Glycosyl transferase, family 2
EXW28_08825	COG0438	transferase activity, transferring glycosyl groups
EXW28_08830	COG1757	Na H antiporter
EXW28_08855	COG0534	Mate efflux family protein
EXW28_08860	COG3340	Belongs to the peptidase S51 family
EXW28_08880	COG0785	Cytochrome C biogenesis protein
EXW28_08885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW28_08900	COG3048	D-serine ammonia-lyase activity
EXW28_08905	COG2733	membrane
EXW28_08945	COG1131	(ABC) transporter
EXW28_08965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW28_08970	COG0528	UMP kinase activity
EXW28_08980	COG1027	Aspartate ammonia-lyase
EXW28_08985	COG0281	malic enzyme
EXW28_08990	COG4191	Histidine kinase
EXW28_08995	COG0784	Response regulator, receiver
EXW28_09000	COG1846	Transcriptional regulator
EXW28_09010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW28_09025	COG2502	aspartate--ammonia ligase
EXW28_09030	COG3620	sequence-specific DNA binding
EXW28_09095	COG1695	Transcriptional regulator
EXW28_09110	COG0477	Major facilitator Superfamily
EXW28_09120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW28_09130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW28_09135	COG2223	nitrite transmembrane transporter activity
EXW28_09140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW28_09155	COG2244	polysaccharide biosynthetic process
EXW28_09160	COG0733	neurotransmitter:sodium symporter activity
EXW28_09170	COG5566	PFAM Mor transcription activator
EXW28_09175	COG2323	membrane
EXW28_09195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW28_09200	COG2132	Multicopper oxidase
EXW28_09210	COG5002	protein histidine kinase activity
EXW28_09215	COG0745	RESPONSE REGULATOR receiver
EXW28_09225	COG0129	dihydroxy-acid dehydratase activity
EXW28_09230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW28_09255	COG2814	Major facilitator Superfamily
EXW28_09260	COG3384	dioxygenase
EXW28_09295	COG1073	alpha beta
EXW28_09300	COG4166	transmembrane transport
EXW28_09305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW28_09325	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW28_09330	COG1054	Belongs to the UPF0176 family
EXW28_09340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW28_09345	COG0531	amino acid
EXW28_09380	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW28_09395	COG4257	antibiotic catabolic process
EXW28_09400	COG2390	Transcriptional regulator
EXW28_09410	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW28_09415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW28_09420	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW28_09435	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW28_09450	COG0583	DNA-binding transcription factor activity
EXW28_09465	COG0006	proline dipeptidase activity
EXW28_09470	COG2132	Multicopper oxidase
EXW28_09485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW28_09505	COG1114	Component of the transport system for branched-chain amino acids
EXW28_09515	COG1276	copper resistance
EXW28_09515	COG2372	response to copper ion
EXW28_09520	COG4549	nuclear export factor GLE1
EXW28_09530	COG0697	spore germination
EXW28_09535	COG0583	DNA-binding transcription factor activity
EXW28_09540	COG1959	2 iron, 2 sulfur cluster binding
EXW28_09545	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW28_09550	COG0778	Nitroreductase
EXW28_09560	COG0628	permease
EXW28_09575	COG1231	oxidoreductase activity
EXW28_09580	COG0523	cobalamin synthesis protein
EXW28_09590	COG0411	ABC transporter
EXW28_09610	COG0583	DNA-binding transcription factor activity
EXW28_09620	COG1942	4-Oxalocrotonate Tautomerase
EXW28_09635	COG0346	lactoylglutathione lyase activity
EXW28_09645	COG1271	oxidase subunit
EXW28_09650	COG1294	oxidase, subunit
EXW28_09655	COG4988	ABC transporter
EXW28_09660	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW28_09685	COG1686	Belongs to the peptidase S11 family
EXW28_09700	COG0791	NLP P60 protein
EXW28_09700	COG1388	LysM domain
EXW28_09710	COG1132	(ABC) transporter
EXW28_09715	COG0745	RESPONSE REGULATOR receiver
EXW28_09720	COG5002	protein histidine kinase activity
EXW28_09725	COG0300	oxidoreductase activity
EXW28_09730	COG4122	O-methyltransferase activity
EXW28_09750	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EXW28_09760	COG0460	homoserine dehydrogenase
EXW28_09770	COG0083	homoserine kinase activity
EXW28_09785	COG1316	TRANSCRIPTIONal
EXW28_09800	COG1285	pathogenesis
EXW28_09805	COG1247	-acetyltransferase
EXW28_09825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW28_09835	COG1082	Xylose isomerase domain protein TIM barrel
EXW28_09845	COG2814	Major facilitator Superfamily
EXW28_09850	COG1279	arginine transmembrane transporter activity
EXW28_09855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW28_09865	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW28_09895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW28_09900	COG0577	efflux transmembrane transporter activity
EXW28_09905	COG2002	toxin-antitoxin pair type II binding
EXW28_09910	COG1404	Belongs to the peptidase S8 family
EXW28_09915	COG0640	Transcriptional regulator
EXW28_09920	COG0667	Aldo Keto reductase
EXW28_09965	COG3949	Membrane
EXW28_09970	COG0783	Belongs to the Dps family
EXW28_09985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW28_09995	COG1231	oxidoreductase activity
EXW28_10000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW28_10005	COG4989	oxidoreductase activity
EXW28_10010	COG0523	cobalamin synthesis protein
EXW28_10015	COG0456	acetyltransferase
EXW28_10020	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW28_10045	COG1136	(ABC) transporter
EXW28_10050	COG0577	efflux transmembrane transporter activity
EXW28_10055	COG0745	RESPONSE REGULATOR receiver
EXW28_10060	COG2205	protein histidine kinase activity
EXW28_10065	COG1902	pentaerythritol trinitrate reductase activity
EXW28_10070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW28_10080	COG4166	transmembrane transport
EXW28_10085	COG0346	lactoylglutathione lyase activity
EXW28_10095	COG0406	alpha-ribazole phosphatase activity
EXW28_10105	COG5337	Spore coat protein CotH
EXW28_10110	COG1051	belongs to the nudix hydrolase family
EXW28_10115	COG0586	Pfam SNARE associated Golgi protein
EXW28_10120	COG2244	polysaccharide biosynthetic process
EXW28_10130	COG0701	Predicted permease
EXW28_10135	COG3689	TIGRFAM TIGR03943 family protein
EXW28_10140	COG1607	acyl-coa hydrolase
EXW28_10150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW28_10165	COG0702	epimerase
EXW28_10170	COG2839	Protein conserved in bacteria
EXW28_10175	COG1253	flavin adenine dinucleotide binding
EXW28_10200	COG1114	Component of the transport system for branched-chain amino acids
EXW28_10205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW28_10225	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW28_10240	COG1876	peptidase activity
EXW28_10245	COG0494	nUDIX hydrolase
EXW28_10255	COG2211	Major facilitator Superfamily
EXW28_10270	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW28_10280	COG0561	phosphatase activity
EXW28_10285	COG1846	Transcriptional regulator
EXW28_10290	COG2814	Major facilitator Superfamily
EXW28_10300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW28_10305	COG4106	trans-aconitate 2-methyltransferase activity
EXW28_10320	COG1819	glycosyl
EXW28_10325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW28_10330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW28_10355	COG0456	acetyltransferase
EXW28_10375	COG3874	Sporulation protein YtfJ
EXW28_10400	COG2226	methyltransferase
EXW28_10430	COG0604	alcohol dehydrogenase
EXW28_10435	COG1595	DNA-templated transcription, initiation
EXW28_10460	COG0426	domain, Protein
EXW28_10460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW28_10470	COG0386	Belongs to the glutathione peroxidase family
EXW28_10475	COG1305	Transglutaminase-like
EXW28_10480	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW28_10485	COG0714	Associated with various cellular activities
EXW28_10490	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW28_10495	COG1140	nitrate reductase beta subunit
EXW28_10500	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW28_10505	COG2181	nitrate reductase activity
EXW28_10510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW28_10515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW28_10520	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW28_10525	COG0303	'Molybdopterin
EXW28_10530	COG0314	molybdopterin synthase activity
EXW28_10540	COG2223	nitrite transmembrane transporter activity
EXW28_10560	COG1648	precorrin-2 dehydrogenase activity
EXW28_10570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW28_10570	COG1587	Uroporphyrinogen-III synthase
EXW28_10575	COG2146	nitrite reductase [NAD(P)H] activity
EXW28_10580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW28_10585	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW28_10615	COG2359	stage V sporulation protein S
EXW28_10625	COG2856	Zn peptidase
EXW28_10640	COG0494	nUDIX hydrolase
EXW28_10645	COG0326	Molecular chaperone. Has ATPase activity
EXW28_10650	COG1396	sequence-specific DNA binding
EXW28_10760	COG0582	viral genome integration into host DNA
EXW28_10775	COG5484	DNA packaging
EXW28_10780	COG1783	phage Terminase large subunit
EXW28_10795	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EXW28_10915	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW28_10925	COG1418	mRNA catabolic process
EXW28_10930	COG0488	(ABC) transporter
EXW28_10950	COG1413	lyase activity
EXW28_10965	COG2521	methyltransferase
EXW28_10965	COG2136	Putative SAM-dependent methyltransferase
EXW28_10970	COG0018	arginyl-trna synthetase
EXW28_11025	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW28_11035	COG0017	Asparaginyl-tRNA synthetase
EXW28_11040	COG0733	neurotransmitter:sodium symporter activity
EXW28_11070	COG2610	gluconate transmembrane transporter activity
EXW28_11080	COG1794	racemase activity, acting on amino acids and derivatives
EXW28_11090	COG0456	acetyltransferase
EXW28_11095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW28_11100	COG1131	(ABC) transporter
EXW28_11105	COG4473	ABC transporter
EXW28_11115	COG0546	phosphoglycolate phosphatase activity
EXW28_11170	COG0768	penicillin binding
EXW28_11180	COG0204	Acyl-transferase
EXW28_11185	COG1272	protein, Hemolysin III
EXW28_11190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW28_11195	COG0805	protein transport
EXW28_11210	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW28_11215	COG1999	signal sequence binding
EXW28_11220	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW28_11225	COG0367	asparagine synthase
EXW28_11240	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW28_11250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW28_11270	COG1335	isochorismatase
EXW28_11280	COG0668	transmembrane transport
EXW28_11285	COG4585	Histidine kinase
EXW28_11285	COG2203	Gaf domain
EXW28_11290	COG2197	response regulator
EXW28_11295	COG1737	Transcriptional regulator
EXW28_11300	COG1064	alcohol dehydrogenase
EXW28_11315	COG1070	Carbohydrate kinase
EXW28_11325	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW28_11345	COG1125	glycine betaine transport
EXW28_11345	COG0517	IMP dehydrogenase activity
EXW28_11350	COG1174	glycine betaine transport
EXW28_11385	COG1253	flavin adenine dinucleotide binding
EXW28_11390	COG1012	belongs to the aldehyde dehydrogenase family
EXW28_11395	COG5506	Protein of unknown function (DUF1694)
EXW28_11410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW28_11415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW28_11420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW28_11425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW28_11430	COG0456	acetyltransferase
EXW28_11435	COG3829	transcription factor binding
EXW28_11440	COG1509	lysine 2,3-aminomutase activity
EXW28_11450	COG4479	Belongs to the UPF0346 family
EXW28_11475	COG3064	Membrane
EXW28_11475	COG0515	serine threonine protein kinase
EXW28_11475	COG4991	sh3 domain protein
EXW28_11485	COG0671	phosphoesterase, PA-phosphatase related
EXW28_11490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW28_11495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW28_11555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW28_11580	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_11600	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW28_11600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW28_11610	COG2814	Major facilitator Superfamily
EXW28_11620	COG0372	Belongs to the citrate synthase family
EXW28_11625	COG2079	MmgE PrpD family protein
EXW28_11630	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW28_11635	COG1960	acyl-CoA dehydrogenase activity
EXW28_11640	COG2084	Dehydrogenase
EXW28_11645	COG1012	belongs to the aldehyde dehydrogenase family
EXW28_11650	COG1280	lysine exporter protein (LysE YggA)
EXW28_11655	COG1024	Enoyl-CoA hydratase
EXW28_11670	COG0420	3'-5' exonuclease activity
EXW28_11690	COG2223	nitrite transmembrane transporter activity
EXW28_11695	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_11700	COG1169	isochorismate synthase
EXW28_11705	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW28_11710	COG3433	isochorismatase activity
EXW28_11710	COG1535	isochorismatase
EXW28_11715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW28_11720	COG3251	PFAM MbtH domain protein
EXW28_11725	COG2814	Major facilitator Superfamily
EXW28_11740	COG0776	regulation of translation
EXW28_11750	COG2318	DinB family
EXW28_11755	COG1115	amino acid carrier protein
EXW28_11770	COG2329	Antibiotic biosynthesis monooxygenase
EXW28_11785	COG1187	pseudouridine synthase activity
EXW28_11790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW28_11795	COG3655	Transcriptional regulator
EXW28_11805	COG1136	(ABC) transporter
EXW28_11815	COG0596	Alpha beta hydrolase
EXW28_11835	COG0028	Belongs to the TPP enzyme family
EXW28_11860	COG1253	flavin adenine dinucleotide binding
EXW28_11910	COG1846	Transcriptional regulator
EXW28_11925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW28_11930	COG1309	transcriptional regulator
EXW28_11940	COG0697	spore germination
EXW28_11945	COG0531	amino acid
EXW28_11960	COG1247	-acetyltransferase
EXW28_12000	COG0596	Alpha beta hydrolase
EXW28_12005	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW28_12015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW28_12045	COG0583	DNA-binding transcription factor activity
EXW28_12050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW28_12065	COG0583	DNA-binding transcription factor activity
EXW28_12070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW28_12075	COG2258	MOSC domain
EXW28_12085	COG1132	(ABC) transporter
EXW28_12090	COG1132	(ABC) transporter
EXW28_12110	COG1396	sequence-specific DNA binding
EXW28_12145	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW28_12150	COG1595	DNA-templated transcription, initiation
EXW28_12170	COG1649	PFAM Uncharacterised BCR, COG1649
EXW28_12190	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW28_12195	COG2971	BadF BadG BcrA BcrD
EXW28_12265	COG3615	Tellurite resistance protein tehB
EXW28_12265	COG0500	methyltransferase
EXW28_12275	COG0693	protein deglycase activity
EXW28_12285	COG0588	phosphoglycerate mutase activity
EXW28_12305	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW28_12310	COG0110	maltose O-acetyltransferase activity
EXW28_12325	COG1136	(ABC) transporter
EXW28_12340	COG5002	protein histidine kinase activity
EXW28_12345	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_12355	COG1686	Belongs to the peptidase S11 family
EXW28_12380	COG0768	penicillin binding
EXW28_12385	COG0745	RESPONSE REGULATOR receiver
EXW28_12390	COG2205	protein histidine kinase activity
EXW28_12395	COG1136	(ABC) transporter
EXW28_12400	COG0577	efflux transmembrane transporter activity
EXW28_12410	COG1595	DNA-templated transcription, initiation
EXW28_12420	COG0768	penicillin binding
EXW28_12425	COG0768	penicillin binding
EXW28_12460	COG1252	NADH dehydrogenase
EXW28_12465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW28_12465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW28_12480	COG0697	spore germination
EXW28_12510	COG3397	chitin binding
EXW28_12515	COG0823	Involved in the tonB-independent uptake of proteins
EXW28_12525	COG1408	metallophosphoesterase
EXW28_12535	COG1131	(ABC) transporter
EXW28_12545	COG1309	transcriptional regulator
EXW28_12555	COG1960	acyl-CoA dehydrogenase activity
EXW28_12560	COG0439	Biotin carboxylase
EXW28_12565	COG0511	ligase activity, forming carbon-carbon bonds
EXW28_12570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW28_12575	COG1024	Enoyl-CoA hydratase
EXW28_12580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW28_12585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW28_12635	COG0572	uridine kinase
EXW28_12640	COG2318	DinB family
EXW28_12670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW28_12700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW28_12725	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_12730	COG1733	regulation of RNA biosynthetic process
EXW28_12755	COG1309	transcriptional regulator
EXW28_12770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW28_12785	COG0697	spore germination
EXW28_12790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW28_12820	COG2323	membrane
EXW28_12835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW28_12840	COG0697	spore germination
EXW28_12860	COG0201	protein transport
EXW28_12870	COG0737	Belongs to the 5'-nucleotidase family
EXW28_12880	COG3227	Zinc metalloprotease (Elastase)
EXW28_12885	COG1523	belongs to the glycosyl hydrolase 13 family
EXW28_12900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW28_12905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW28_12910	COG1073	alpha beta
EXW28_12920	COG0577	efflux transmembrane transporter activity
EXW28_12925	COG1136	(ABC) transporter
EXW28_12955	COG5002	protein histidine kinase activity
EXW28_12960	COG0745	RESPONSE REGULATOR receiver
EXW28_12965	COG1011	Hydrolase
EXW28_12990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW28_12995	COG1183	phosphatidylcholine synthase activity
EXW28_13010	COG1132	(ABC) transporter
EXW28_13020	COG3961	Belongs to the TPP enzyme family
EXW28_13040	COG0322	excinuclease ABC activity
EXW28_13065	COG2318	DinB family
EXW28_13080	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW28_13105	COG3878	Protein conserved in bacteria
EXW28_13130	COG1051	belongs to the nudix hydrolase family
EXW28_13135	COG0592	DNA-directed DNA polymerase activity
EXW28_13140	COG2816	NAD+ diphosphatase activity
EXW28_13150	COG2223	nitrite transmembrane transporter activity
EXW28_13155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW28_13165	COG0494	nUDIX hydrolase
EXW28_13185	COG0697	spore germination
EXW28_13190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW28_13205	COG0584	glycerophosphoryl diester phosphodiesterase
EXW28_13220	COG1733	regulation of RNA biosynthetic process
EXW28_13230	COG2814	Major facilitator Superfamily
EXW28_13245	COG1132	(ABC) transporter
EXW28_13245	COG2375	cellular response to nickel ion
EXW28_13250	COG1132	(ABC) transporter
EXW28_13285	COG0768	penicillin binding
EXW28_13290	COG0671	phosphoesterase, PA-phosphatase related
EXW28_13295	COG0604	alcohol dehydrogenase
EXW28_13300	COG5002	protein histidine kinase activity
EXW28_13305	COG0745	RESPONSE REGULATOR receiver
EXW28_13315	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW28_13325	COG2205	protein histidine kinase activity
EXW28_13340	COG1122	ATPase activity
EXW28_13345	COG4720	Psort location CytoplasmicMembrane, score
EXW28_13350	COG1794	racemase activity, acting on amino acids and derivatives
EXW28_13355	COG1819	glycosyl
EXW28_13365	COG0768	penicillin binding
EXW28_13370	COG5002	protein histidine kinase activity
EXW28_13375	COG0561	phosphatase activity
EXW28_13415	COG2124	cytochrome p450
EXW28_13465	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW28_13475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW28_13500	COG0577	efflux transmembrane transporter activity
EXW28_13505	COG1136	(ABC) transporter
EXW28_13520	COG0488	(ABC) transporter
EXW28_13525	COG0667	Aldo Keto reductase
EXW28_13530	COG0583	DNA-binding transcription factor activity
EXW28_13535	COG2205	protein histidine kinase activity
EXW28_13540	COG0745	RESPONSE REGULATOR receiver
EXW28_13550	COG3773	Cell wall hydrolase
EXW28_13555	COG0604	alcohol dehydrogenase
EXW28_13585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW28_13600	COG2959	enzyme of heme biosynthesis
EXW28_13630	COG3483	tryptophan 2,3-dioxygenase activity
EXW28_13635	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW28_13640	COG3844	kynureninase activity
EXW28_13645	COG1309	transcriptional regulator
EXW28_13675	COG1349	DNA-binding transcription factor activity
EXW28_13705	COG2223	nitrite transmembrane transporter activity
EXW28_13715	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_13720	COG0456	acetyltransferase
EXW28_13720	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW28_13755	COG4176	ABC-type proline glycine betaine transport system permease component
EXW28_13760	COG4175	Glycine betaine
EXW28_13760	COG0517	IMP dehydrogenase activity
EXW28_13785	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW28_13790	COG2153	protein acetylation
EXW28_13795	COG3397	chitin binding
EXW28_13805	COG1819	glycosyl
EXW28_13820	COG2205	protein histidine kinase activity
EXW28_13825	COG2315	Protein conserved in bacteria
EXW28_13870	COG3973	AAA domain
EXW28_13885	COG2105	PFAM AIG2 family protein
EXW28_13890	COG0514	ATP-dependent DNA helicase (RecQ)
EXW28_13910	COG4637	Psort location Cytoplasmic, score
EXW28_13930	COG1227	inorganic diphosphatase activity
EXW28_13935	COG3397	chitin binding
EXW28_13940	COG2318	DinB family
EXW28_13955	COG1162	GTPase activity
EXW28_13960	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW28_13965	COG1115	amino acid carrier protein
EXW28_13970	COG1012	belongs to the aldehyde dehydrogenase family
EXW28_13975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW28_13985	COG3938	Belongs to the proline racemase family
EXW28_13990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW28_14040	COG0586	Pfam SNARE associated Golgi protein
EXW28_14055	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW28_14060	COG4166	transmembrane transport
EXW28_14070	COG4948	Mandelate Racemase Muconate Lactonizing
EXW28_14090	COG0667	Aldo Keto reductase
EXW28_14135	COG2936	dipeptidyl-peptidase activity
EXW28_14145	COG0745	RESPONSE REGULATOR receiver
EXW28_14175	COG1164	Oligoendopeptidase f
EXW28_14195	COG1307	EDD domain protein, DegV family
EXW28_14225	COG1335	isochorismatase
EXW28_14240	COG2814	Major facilitator Superfamily
EXW28_14250	COG1664	Polymer-forming cytoskeletal
EXW28_14255	COG0789	Transcriptional regulator
EXW28_14260	COG4533	DNA binding
EXW28_14265	COG0477	Major facilitator Superfamily
EXW28_14265	COG2814	Major facilitator Superfamily
EXW28_14280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW28_14285	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW28_14290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW28_14295	COG0438	transferase activity, transferring glycosyl groups
EXW28_14310	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW28_14315	COG0438	transferase activity, transferring glycosyl groups
EXW28_14320	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW28_14335	COG2261	transglycosylase associated protein
EXW28_14350	COG2226	methyltransferase
EXW28_14385	COG0436	Aminotransferase
EXW28_14390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW28_14415	COG1131	(ABC) transporter
EXW28_14420	COG2188	Transcriptional regulator
EXW28_14465	COG0628	permease
EXW28_14495	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW28_14505	COG0697	spore germination
EXW28_14510	COG2318	DinB family
EXW28_14555	COG2814	Major facilitator Superfamily
EXW28_14560	COG1368	sulfuric ester hydrolase activity
EXW28_14570	COG0488	(ABC) transporter
EXW28_14575	COG2409	Drug exporters of the RND superfamily
EXW28_14575	COG1033	growth of symbiont in host cell
EXW28_14585	COG1309	transcriptional regulator
EXW28_14605	COG0287	Prephenate dehydrogenase
EXW28_14620	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW28_14620	COG1605	Chorismate mutase
EXW28_14670	COG3584	3D domain protein
EXW28_14670	COG1388	LysM domain
EXW28_14680	COG0346	lactoylglutathione lyase activity
EXW28_14715	COG0579	oxidoreductase
EXW28_14725	COG2390	Transcriptional regulator
EXW28_14745	COG1830	Aldolase
EXW28_14750	COG2226	methyltransferase
EXW28_14765	COG0346	lactoylglutathione lyase activity
EXW28_14770	COG2329	Antibiotic biosynthesis monooxygenase
EXW28_14790	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW28_14795	COG2207	Transcriptional regulator
EXW28_14800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW28_14805	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW28_14810	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW28_14815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW28_14820	COG3239	Fatty acid desaturase
EXW28_14840	COG3655	Transcriptional regulator
EXW28_14855	COG4377	Putative membrane peptidase family (DUF2324)
EXW28_14865	COG3279	Response regulator of the LytR AlgR family
EXW28_14880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW28_14885	COG0346	lactoylglutathione lyase activity
EXW28_14920	COG0714	Associated with various cellular activities
EXW28_14940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW28_14945	COG0753	catalase activity
EXW28_14955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW28_14975	COG0778	Nitroreductase
EXW28_14980	COG1846	Transcriptional regulator
EXW28_15000	COG1051	belongs to the nudix hydrolase family
EXW28_15020	COG1725	Transcriptional regulator
EXW28_15055	COG2207	Transcriptional regulator
EXW28_15060	COG0456	acetyltransferase
EXW28_15075	COG0697	spore germination
EXW28_15080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW28_15085	COG1671	Belongs to the UPF0178 family
EXW28_15100	COG0642	Histidine kinase
EXW28_15105	COG0745	RESPONSE REGULATOR receiver
EXW28_15110	COG0596	Alpha beta hydrolase
EXW28_15120	COG0456	acetyltransferase
EXW28_15120	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW28_15145	COG0730	response to heat
EXW28_15155	COG0833	amino acid
EXW28_15165	COG4335	DNA alkylation repair
EXW28_15200	COG0768	penicillin binding
EXW28_15210	COG3104	oligopeptide transport
EXW28_15215	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW28_15230	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW28_15235	COG1984	allophanate hydrolase subunit 2
EXW28_15240	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW28_15245	COG1414	Transcriptional regulator
EXW28_15265	COG1960	acyl-CoA dehydrogenase activity
EXW28_15290	COG0640	Transcriptional regulator
EXW28_15310	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW28_15325	COG0574	Belongs to the PEP-utilizing enzyme family
EXW28_15325	COG3848	Pyruvate phosphate dikinase
EXW28_15350	COG1136	(ABC) transporter
EXW28_15385	COG1073	alpha beta
EXW28_15430	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW28_15450	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW28_15455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW28_15460	COG1121	(ABC) transporter
EXW28_15475	COG1999	signal sequence binding
EXW28_15480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW28_15485	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW28_15510	COG0798	PFAM Bile acid sodium symporter
EXW28_15515	COG0346	lactoylglutathione lyase activity
EXW28_15520	COG0640	Transcriptional regulator
EXW28_15570	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_15575	COG1522	sequence-specific DNA binding
EXW28_15590	COG0346	lactoylglutathione lyase activity
EXW28_15610	COG2226	methyltransferase
EXW28_15620	COG2814	Major facilitator Superfamily
EXW28_15645	COG0745	RESPONSE REGULATOR receiver
EXW28_15650	COG3850	Histidine kinase
EXW28_15650	COG5002	protein histidine kinase activity
EXW28_15680	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW28_15720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW28_15750	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW28_15770	COG1136	(ABC) transporter
EXW28_15775	COG0577	efflux transmembrane transporter activity
EXW28_15795	COG3850	Histidine kinase
EXW28_15795	COG5002	protein histidine kinase activity
EXW28_15810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW28_15830	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW28_15850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW28_15910	COG2814	Major facilitator Superfamily
EXW28_15930	COG1876	peptidase activity
EXW28_15935	COG2843	Capsule synthesis protein
EXW28_15950	COG0477	Major facilitator Superfamily
EXW28_15965	COG1846	Transcriptional regulator
EXW28_15970	COG2814	Major facilitator Superfamily
EXW28_15985	COG0789	Transcriptional regulator
EXW28_16020	COG1476	TRANSCRIPTIONal
EXW28_16035	COG1288	antiporter activity
EXW28_16040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW28_16155	COG4187	Peptidase family M20/M25/M40
EXW28_16160	COG1414	Transcriptional regulator
EXW28_16170	COG0833	amino acid
EXW28_16185	COG2031	fatty acid transporter
EXW28_16195	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW28_16250	COG2356	endonuclease I
EXW28_16255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW28_16275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW28_16295	COG1785	Belongs to the alkaline phosphatase family
EXW28_16300	COG0778	Nitroreductase
EXW28_16305	COG1733	regulation of RNA biosynthetic process
EXW28_16320	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_16330	COG1131	(ABC) transporter
EXW28_16360	COG1011	Hydrolase
EXW28_16365	COG2365	Tyrosine phosphatase family
EXW28_16390	COG0346	lactoylglutathione lyase activity
EXW28_16395	COG1940	carbohydrate kinase activity
EXW28_16400	COG0738	Major facilitator superfamily
EXW28_16405	COG0110	maltose O-acetyltransferase activity
EXW28_16420	COG0628	permease
EXW28_16425	COG2261	transglycosylase associated protein
EXW28_16455	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW28_16465	COG1253	flavin adenine dinucleotide binding
EXW28_16470	COG0789	Transcriptional regulator
EXW28_16475	COG0697	spore germination
EXW28_16480	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW28_16485	COG3813	Protein conserved in bacteria
EXW28_16490	COG2706	6-phosphogluconolactonase activity
EXW28_16495	COG1070	Carbohydrate kinase
EXW28_16505	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW28_16510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW28_16525	COG0814	amino acid
EXW28_16545	COG1393	Belongs to the ArsC family
EXW28_16555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW28_16570	COG0494	nUDIX hydrolase
EXW28_16595	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_16605	COG0318	PFAM AMP-dependent synthetase and ligase
EXW28_16610	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW28_16615	COG1733	regulation of RNA biosynthetic process
EXW28_16630	COG1191	sigma factor activity
EXW28_16660	COG1876	peptidase activity
EXW28_16685	COG0741	lytic transglycosylase activity
EXW28_16705	COG5002	protein histidine kinase activity
EXW28_16710	COG0745	RESPONSE REGULATOR receiver
EXW28_16730	COG0657	acetylesterase activity
EXW28_16740	COG2814	Major facilitator Superfamily
EXW28_16745	COG1309	transcriptional regulator
EXW28_16755	COG3226	Transcriptional regulator
EXW28_16760	COG1280	lysine exporter protein (LysE YggA)
EXW28_16790	COG0814	amino acid
EXW28_16815	COG1151	hydroxylamine reductase activity
EXW28_16860	COG2072	flavoprotein involved in K transport
EXW28_16905	COG1695	Transcriptional regulator
EXW28_16910	COG0604	alcohol dehydrogenase
EXW28_16915	COG1113	amino acid transport
EXW28_16925	COG2814	Major facilitator Superfamily
EXW28_16955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW28_16960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW28_16980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW28_16985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW28_16990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW28_16995	COG3739	integral membrane protein
EXW28_17020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW28_17025	COG0583	DNA-binding transcription factor activity
EXW28_17050	COG1193	negative regulation of DNA recombination
EXW28_17070	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW28_17075	COG1164	Oligoendopeptidase f
EXW28_17080	COG2957	Belongs to the agmatine deiminase family
EXW28_17100	COG3781	membrane
EXW28_17115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW28_17150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW28_17155	COG0640	Transcriptional regulator
EXW28_17160	COG0604	alcohol dehydrogenase
EXW28_17165	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW28_17175	COG0457	Tetratricopeptide repeat
EXW28_17180	COG2808	Putative FMN-binding domain
EXW28_17190	COG0277	FAD linked oxidase domain protein
EXW28_17210	COG1285	pathogenesis
EXW28_17225	COG2514	catechol 2,3-dioxygenase activity
EXW28_17230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW28_17235	COG1126	abc transporter atp-binding protein
EXW28_17240	COG0765	amino acid transport
EXW28_17245	COG2720	vancomycin resistance protein
EXW28_17270	COG1278	Cold shock
EXW28_17280	COG0716	FMN binding
EXW28_17290	COG0494	nUDIX hydrolase
EXW28_17310	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_17320	COG0165	Argininosuccinate lyase
EXW28_17335	COG4145	pantothenate transmembrane transporter activity
EXW28_17345	COG1012	belongs to the aldehyde dehydrogenase family
EXW28_17350	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_17360	COG1657	PFAM Prenyltransferase squalene oxidase
EXW28_17365	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW28_17370	COG2962	Rard protein
EXW28_17375	COG3326	Membrane
EXW28_17405	COG2226	methyltransferase
EXW28_17410	COG4166	transmembrane transport
EXW28_17415	COG4166	transmembrane transport
EXW28_17420	COG4166	transmembrane transport
EXW28_17430	COG1131	(ABC) transporter
EXW28_17450	COG0673	inositol 2-dehydrogenase activity
EXW28_17455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW28_17460	COG0187	DNA topoisomerase II activity
EXW28_17465	COG1832	CoA-binding protein
EXW28_17470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW28_17475	COG0745	RESPONSE REGULATOR receiver
EXW28_17485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW28_17485	COG1328	CTP reductase activity
EXW28_17495	COG4841	protein insertion into membrane
EXW28_17500	COG0824	Thioesterase
EXW28_17525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW28_17540	COG1266	CAAX protease self-immunity
EXW28_17545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW28_17575	COG2211	Major facilitator Superfamily
EXW28_17585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW28_17600	COG0183	Belongs to the thiolase family
EXW28_17605	COG0318	PFAM AMP-dependent synthetase and ligase
EXW28_17610	COG1268	BioY protein
EXW28_17615	COG0318	PFAM AMP-dependent synthetase and ligase
EXW28_17620	COG1396	sequence-specific DNA binding
EXW28_17660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW28_17675	COG5002	protein histidine kinase activity
EXW28_17685	COG0400	carboxylic ester hydrolase activity
EXW28_17690	COG0346	lactoylglutathione lyase activity
EXW28_17700	COG0069	glutamate synthase activity
EXW28_17705	COG1902	pentaerythritol trinitrate reductase activity
EXW28_17710	COG1329	Transcriptional regulator
EXW28_17715	COG0010	Belongs to the arginase family
EXW28_17725	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW28_17730	COG2986	histidine ammonia-lyase
EXW28_17740	COG2226	methyltransferase
EXW28_17770	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW28_17775	COG0785	Cytochrome C biogenesis protein
EXW28_17790	COG1473	amidohydrolase
EXW28_17795	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW28_17800	COG1131	(ABC) transporter
EXW28_17810	COG0583	DNA-binding transcription factor activity
EXW28_17820	COG1346	cytolysis
EXW28_17835	COG0730	response to heat
EXW28_17845	COG3409	Peptidoglycan-binding domain 1 protein
EXW28_17845	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW28_17865	COG1132	(ABC) transporter
EXW28_17870	COG1132	(ABC) transporter
EXW28_17875	COG3763	UPF0154 protein
EXW28_17895	COG3639	organic phosphonate transmembrane transporter activity
EXW28_17905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW28_17910	COG0737	Belongs to the 5'-nucleotidase family
EXW28_17920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW28_17925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW28_17940	COG1695	Transcriptional regulator
EXW28_17945	COG1132	(ABC) transporter
EXW28_17980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW28_17990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW28_17995	COG3420	alginic acid biosynthetic process
EXW28_17995	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW28_18025	COG1216	Glycosyl transferase, family 2
EXW28_18045	COG0463	Glycosyl transferase, family 2
EXW28_18045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW28_18050	COG0438	transferase activity, transferring glycosyl groups
EXW28_18055	COG0438	transferase activity, transferring glycosyl groups
EXW28_18060	COG1086	Polysaccharide biosynthesis protein
EXW28_18065	COG0489	protein tyrosine kinase activity
EXW28_18070	COG3944	biosynthesis protein
EXW28_18110	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW28_18110	COG1388	LysM domain
EXW28_18110	COG3409	Peptidoglycan-binding domain 1 protein
EXW28_18115	COG4824	toxin secretion phage lysis holin
EXW28_18260	COG1595	DNA-templated transcription, initiation
EXW28_18400	COG0174	glutamine synthetase
EXW28_18405	COG0789	Transcriptional regulator
EXW28_18410	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW28_18415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW28_18420	COG2860	membrane
EXW28_18425	COG0464	growth
EXW28_18445	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW28_18455	COG3584	3D domain protein
EXW28_18455	COG1388	LysM domain
EXW28_18460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW28_18460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW28_18460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW28_18465	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW28_18470	COG1349	DNA-binding transcription factor activity
EXW28_18475	COG1979	alcohol dehydrogenase
EXW28_18480	COG2322	membrane
EXW28_18490	COG1113	amino acid transport
EXW28_18505	COG1473	amidohydrolase
EXW28_18510	COG1408	metallophosphoesterase
EXW28_18515	COG2116	formate transmembrane transporter activity
EXW28_18530	COG2217	Heavy metal translocating P-type atpase
EXW28_18535	COG2608	mercury ion transmembrane transporter activity
EXW28_18540	COG1937	Protein conserved in bacteria
EXW28_18575	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW28_18580	COG2819	hydrolase of the alpha beta superfamily
EXW28_18585	COG1120	ATPase activity
EXW28_18590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW28_18595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW28_18600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW28_18605	COG0708	Exodeoxyribonuclease III
EXW28_18610	COG2169	Transcriptional regulator
EXW28_18615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW28_18620	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW28_18630	COG2706	6-phosphogluconolactonase activity
EXW28_18635	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW28_18640	COG2364	Membrane
EXW28_18660	COG0346	lactoylglutathione lyase activity
EXW28_18665	COG3300	MHYT domain
EXW28_18665	COG5001	Diguanylate cyclase
EXW28_18705	COG1346	cytolysis
EXW28_18715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW28_18720	COG2945	thiolester hydrolase activity
EXW28_18720	COG0596	Alpha beta hydrolase
EXW28_18725	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW28_18735	COG2188	Transcriptional regulator
EXW28_18740	COG2723	6-phospho-beta-galactosidase activity
EXW28_18745	COG0840	transmembrane signaling receptor activity
EXW28_18755	COG3773	Cell wall hydrolase
EXW28_18770	COG1368	sulfuric ester hydrolase activity
EXW28_18775	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW28_18790	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW28_18800	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW28_18805	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW28_18815	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW28_18820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW28_18825	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW28_18830	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW28_18830	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW28_18840	COG2359	stage V sporulation protein S
EXW28_18845	COG1692	metallophosphoesterase
EXW28_18850	COG1418	mRNA catabolic process
EXW28_18855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW28_18860	COG1058	Belongs to the CinA family
EXW28_18860	COG1546	Belongs to the CinA family
EXW28_18865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW28_18870	COG1426	Protein conserved in bacteria
EXW28_18885	COG0300	oxidoreductase activity
EXW28_18890	COG0612	Peptidase, M16
EXW28_18895	COG0612	Peptidase, M16
EXW28_18900	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW28_18905	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW28_18910	COG3845	ABC transporter
EXW28_18915	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW28_18920	COG2188	Transcriptional regulator
EXW28_18925	COG1674	ftsk spoiiie
EXW28_18935	COG0740	serine-type endopeptidase activity
EXW28_18940	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW28_18950	COG0527	aspartate kinase activity
EXW28_18955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW28_18960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW28_18965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW28_18970	COG1873	PFAM PRC-barrel domain
EXW28_18975	COG0612	Peptidase, M16
EXW28_18980	COG0726	polysaccharide deacetylase
EXW28_18985	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW28_18995	COG0196	riboflavin kinase activity
EXW28_19005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW28_19010	COG1550	Protein conserved in bacteria
EXW28_19015	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW28_19020	COG1358	cellular component organization or biogenesis
EXW28_19025	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW28_19030	COG0195	Participates in both transcription termination and antitermination
EXW28_19035	COG0779	Required for maturation of 30S ribosomal subunits
EXW28_19045	COG0442	prolyl-tRNA aminoacylation
EXW28_19050	COG0750	zinc metalloprotease
EXW28_19060	COG4589	Belongs to the CDS family
EXW28_19070	COG0233	cytoplasmic translational termination
EXW28_19075	COG0528	UMP kinase activity
EXW28_19080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW28_19085	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW28_19090	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW28_19095	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW28_19100	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW28_19105	COG4974	Belongs to the 'phage' integrase family
EXW28_19110	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW28_19115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW28_19120	COG0758	DNA mediated transformation
EXW28_19125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW28_19130	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW28_19135	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW28_19150	COG0335	large ribosomal subunit rRNA binding
EXW28_19155	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW28_19160	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW28_19165	COG1837	Belongs to the UPF0109 family
EXW28_19175	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW28_19180	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EXW28_19185	COG0552	protein localization to endoplasmic reticulum
EXW28_19190	COG1196	nuclear chromosome segregation
EXW28_19195	COG0571	ribonuclease III activity
EXW28_19200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW28_19205	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_19210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW28_19215	COG0416	fatty acid biosynthetic process
EXW28_19220	COG2050	protein possibly involved in aromatic compounds catabolism
EXW28_19220	COG1349	DNA-binding transcription factor activity
EXW28_19225	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW28_19235	COG1461	Dihydroxyacetone kinase
EXW28_19240	COG1302	Protein conserved in bacteria
EXW28_19255	COG1564	THIamine pyrophosphokinase
EXW28_19260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW28_19270	COG2815	serine threonine protein kinase
EXW28_19270	COG0515	serine threonine protein kinase
EXW28_19275	COG0631	protein serine/threonine phosphatase activity
EXW28_19280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW28_19285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW28_19285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW28_19290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW28_19295	COG0242	peptide deformylase activity
EXW28_19300	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW28_19305	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW28_19310	COG1758	RNA polymerase activity
EXW28_19325	COG1561	YicC-like family, N-terminal region
EXW28_19330	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW28_19345	COG0006	proline dipeptidase activity
EXW28_19405	COG0167	dihydroorotate dehydrogenase activity
EXW28_19410	COG0543	2 iron, 2 sulfur cluster binding
EXW28_19415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW28_19425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW28_19430	COG0540	Belongs to the ATCase OTCase family
EXW28_19440	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW28_19445	COG0564	pseudouridine synthase activity
EXW28_19450	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW28_19460	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW28_19465	COG3599	regulation of cell shape
EXW28_19470	COG2302	S4 RNA-binding domain
EXW28_19475	COG0762	integral membrane protein
EXW28_19480	COG1799	cell septum assembly
EXW28_19485	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW28_19495	COG1873	PFAM PRC-barrel domain
EXW28_19500	COG1191	sigma factor activity
EXW28_19505	COG1191	sigma factor activity
EXW28_19515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW28_19520	COG0849	cell division
EXW28_19525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW28_19540	COG0772	Belongs to the SEDS family
EXW28_19545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW28_19550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW28_19555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW28_19560	COG0768	penicillin binding
EXW28_19565	COG0768	penicillin binding
EXW28_19575	COG0275	rRNA processing
EXW28_19580	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW28_19585	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW28_19590	COG0454	-acetyltransferase
EXW28_19600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW28_19605	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW28_19610	COG1323	Belongs to the UPF0348 family
EXW28_19615	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW28_19620	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW28_19625	COG3314	Sporulation integral membrane protein YlbJ
EXW28_19630	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EXW28_19635	COG0742	ribosomal rna small subunit methyltransferase
EXW28_19645	COG4471	UPF0298 protein
EXW28_19650	COG3679	Belongs to the UPF0342 family
EXW28_19655	COG0406	alpha-ribazole phosphatase activity
EXW28_19670	COG2340	Cysteine-rich secretory protein family
EXW28_19680	COG3336	cytochrome c oxidase
EXW28_19705	COG0109	protoheme IX farnesyltransferase activity
EXW28_19710	COG1612	heme a metabolic process
EXW28_19715	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW28_19725	COG0772	Belongs to the SEDS family
EXW28_19730	COG4838	Belongs to the UPF0358 family
EXW28_19735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW28_19740	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW28_19750	COG4896	Protein conserved in bacteria
EXW28_19765	COG1217	gtp-binding protein TYPA
EXW28_19775	COG0483	inositol monophosphate 1-phosphatase activity
EXW28_19785	COG4493	Belongs to the UPF0637 family
EXW28_19790	COG4476	Belongs to the UPF0223 family
EXW28_19800	COG1982	Orn Lys Arg decarboxylase major
EXW28_19845	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW28_19850	COG0022	dehydrogenase e1 component
EXW28_19855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW28_19870	COG0561	phosphatase activity
EXW28_19880	COG5503	Protein of unknown function (DUF1447)
EXW28_19885	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW28_19890	COG0569	domain protein
EXW28_19900	COG1473	amidohydrolase
EXW28_19905	COG2171	N-acyltransferase activity
EXW28_19910	COG0583	DNA-binding transcription factor activity
EXW28_19915	COG0517	IMP dehydrogenase activity
EXW28_19925	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW28_19935	COG4703	Protein of unknown function (DUF1797)
EXW28_19950	COG2200	EAL domain
EXW28_19955	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_19960	COG1408	metallophosphoesterase
EXW28_20005	COG2814	Major facilitator Superfamily
EXW28_20015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW28_20025	COG3209	COG3209 Rhs family protein
EXW28_20035	COG2205	protein histidine kinase activity
EXW28_20045	COG0436	Aminotransferase
EXW28_20050	COG1609	Transcriptional regulator
EXW28_20055	COG3833	ABC-type maltose transport systems, permease component
EXW28_20060	COG1175	transmembrane transport
EXW28_20065	COG2182	Extracellular solute-binding protein
EXW28_20075	COG0366	Alpha amylase catalytic
EXW28_20080	COG3842	ATPase activity
EXW28_20125	COG0183	Belongs to the thiolase family
EXW28_20160	COG1695	Transcriptional regulator
EXW28_20165	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_20175	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW28_20180	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW28_20185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW28_20190	COG0436	Aminotransferase
EXW28_20195	COG1850	ribulose-bisphosphate carboxylase activity
EXW28_20200	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW28_20205	COG0235	Class ii aldolase
EXW28_20210	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW28_20225	COG2084	Dehydrogenase
EXW28_20235	COG2199	diguanylate cyclase activity
EXW28_20240	COG0778	Nitroreductase
EXW28_20265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW28_20265	COG2190	(PTS) system
EXW28_20265	COG1263	PTS System
EXW28_20270	COG3711	transcriptional antiterminator
EXW28_20280	COG2188	Transcriptional regulator
EXW28_20285	COG0363	glucosamine-6-phosphate deaminase activity
EXW28_20300	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW28_20310	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW28_20320	COG1547	Domain of unknown function (DUF309)
EXW28_20330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW28_20335	COG4086	secreted protein
EXW28_20340	COG0561	phosphatase activity
EXW28_20345	COG0697	spore germination
EXW28_20360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW28_20385	COG0733	neurotransmitter:sodium symporter activity
EXW28_20405	COG1686	Belongs to the peptidase S11 family
EXW28_20410	COG1725	Transcriptional regulator
EXW28_20415	COG1131	(ABC) transporter
EXW28_20435	COG1846	Transcriptional regulator
EXW28_20450	COG0598	Magnesium transport protein CorA
EXW28_20465	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW28_20475	COG4974	Belongs to the 'phage' integrase family
EXW28_20485	COG0735	belongs to the Fur family
EXW28_20490	COG1300	Membrane
EXW28_20510	COG0667	Aldo Keto reductase
EXW28_20515	COG0656	L-ascorbic acid biosynthetic process
EXW28_20520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW28_20520	COG0456	acetyltransferase
EXW28_20530	COG0737	Belongs to the 5'-nucleotidase family
EXW28_20530	COG1525	nuclease
EXW28_20530	COG4085	toxin activity
EXW28_20535	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW28_20545	COG0596	Alpha beta hydrolase
EXW28_20550	COG2056	Na+-H+ antiporter family
EXW28_20555	COG1609	Transcriptional regulator
EXW28_20560	COG0456	acetyltransferase
EXW28_20565	COG1073	alpha beta
EXW28_20580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW28_20580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW28_20585	COG0307	riboflavin synthase, alpha
EXW28_20590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW28_20590	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW28_20605	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW28_20610	COG4106	trans-aconitate 2-methyltransferase activity
EXW28_20615	COG2226	methyltransferase
EXW28_20615	COG1073	alpha beta
EXW28_20620	COG0156	8-amino-7-oxononanoate synthase activity
EXW28_20630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW28_20645	COG1757	Na H antiporter
EXW28_20650	COG0737	Belongs to the 5'-nucleotidase family
EXW28_20660	COG1522	sequence-specific DNA binding
EXW28_20685	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW28_20695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW28_20710	COG0300	oxidoreductase activity
EXW28_20715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW28_20720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW28_20725	COG1760	l-serine dehydratase
EXW28_20730	COG1760	l-serine dehydratase
EXW28_20740	COG1234	tRNA 3'-trailer cleavage
EXW28_20775	COG1131	(ABC) transporter
EXW28_20800	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW28_20805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW28_20815	COG1376	ErfK ybiS ycfS ynhG family protein
EXW28_20820	COG4129	membrane
EXW28_20825	COG1126	abc transporter atp-binding protein
EXW28_20830	COG0765	amino acid transport
EXW28_20835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW28_20850	COG2323	membrane
EXW28_20855	COG0772	Belongs to the SEDS family
EXW28_20865	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW28_20870	COG0022	dehydrogenase e1 component
EXW28_20875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW28_20880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW28_20885	COG3426	butyrate kinase activity
EXW28_20895	COG0280	phosphate acetyltransferase
EXW28_20905	COG3290	protein histidine kinase activity
EXW28_20905	COG3829	transcription factor binding
EXW28_20915	COG0584	glycerophosphoryl diester phosphodiesterase
EXW28_20920	COG3093	addiction module antidote protein HigA
EXW28_20930	COG0745	RESPONSE REGULATOR receiver
EXW28_20940	COG0750	zinc metalloprotease
EXW28_20945	COG0497	DNA recombination
EXW28_20950	COG1438	arginine binding
EXW28_20955	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW28_20960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW28_20965	COG0142	geranyltranstransferase activity
EXW28_20970	COG1722	exodeoxyribonuclease VII activity
EXW28_20975	COG1570	exodeoxyribonuclease VII activity
EXW28_20980	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW28_20985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW28_20990	COG1302	Protein conserved in bacteria
EXW28_20995	COG0439	Biotin carboxylase
EXW28_21000	COG0511	ligase activity, forming carbon-carbon bonds
EXW28_21045	COG3854	ATPases associated with a variety of cellular activities
EXW28_21065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW28_21070	COG0006	proline dipeptidase activity
EXW28_21075	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW28_21085	COG3872	metal-dependent enzyme
EXW28_21095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW28_21100	COG1321	iron dependent repressor
EXW28_21130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW28_21140	COG1609	Transcriptional regulator
EXW28_21150	COG2076	Multidrug Resistance protein
EXW28_21155	COG2076	Multidrug Resistance protein
EXW28_21190	COG1725	Transcriptional regulator
EXW28_21205	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW28_21210	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW28_21215	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW28_21220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW28_21250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW28_21275	COG4970	Tfp pilus assembly protein FimT
EXW28_21285	COG1459	type II secretion system
EXW28_21290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW28_21345	COG0646	methionine synthase
EXW28_21345	COG1410	methionine synthase
EXW28_21350	COG0646	methionine synthase
EXW28_21350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW28_21355	COG0626	cystathionine gamma-synthase activity
EXW28_21360	COG0626	cystathionine gamma-synthase activity
EXW28_21375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW28_21385	COG1940	carbohydrate kinase activity
EXW28_21390	COG4483	Protein conserved in bacteria
EXW28_21395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW28_21400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW28_21405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW28_21410	COG0704	Plays a role in the regulation of phosphate uptake
EXW28_21425	COG0581	inorganic phosphate transmembrane transporter activity
EXW28_21430	COG0573	inorganic phosphate transmembrane transporter activity
EXW28_21435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW28_21440	COG0768	penicillin binding
EXW28_21445	COG0477	Major facilitator Superfamily
EXW28_21450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW28_21475	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW28_21480	COG0735	belongs to the Fur family
EXW28_21485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW28_21490	COG1121	(ABC) transporter
EXW28_21495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW28_21505	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW28_21520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW28_21525	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW28_21530	COG2384	SAM-dependent methyltransferase
EXW28_21540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW28_21545	COG0358	DNA primase activity
EXW28_21555	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW28_21560	COG0517	IMP dehydrogenase activity
EXW28_21565	COG1381	Involved in DNA repair and RecF pathway recombination
EXW28_21575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW28_21580	COG0295	cytidine deaminase activity
EXW28_21585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW28_21590	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW28_21595	COG1480	7TM receptor with intracellular HD hydrolase
EXW28_21600	COG1702	phosphate starvation-inducible protein PhoH
EXW28_21615	COG1610	YqeY-like protein
EXW28_21620	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW28_21625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW28_21630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW28_21640	COG0484	heat shock protein binding
EXW28_21645	COG0443	Heat shock 70 kDa protein
EXW28_21655	COG1420	regulation of RNA biosynthetic process
EXW28_21660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW28_21665	COG1733	regulation of RNA biosynthetic process
EXW28_21670	COG0481	GTPase activity
EXW28_21680	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW28_21685	COG0268	Binds directly to 16S ribosomal RNA
EXW28_21690	COG1466	dna polymerase III delta subunit
EXW28_21700	COG2333	competence protein COMEC
EXW28_21700	COG0658	competence protein
EXW28_21705	COG2131	deaminase
EXW28_21710	COG1555	photosystem II stabilization
EXW28_21710	COG1596	polysaccharide export
EXW28_21715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW28_21720	COG2226	methyltransferase
EXW28_21725	COG0799	negative regulation of ribosome biogenesis
EXW28_21730	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW28_21735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW28_21740	COG1534	Rna-binding protein
EXW28_21745	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW28_21750	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW28_21755	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW28_21765	COG0688	phosphatidylethanolamine metabolic process
EXW28_21775	COG1595	DNA-templated transcription, initiation
EXW28_21780	COG2357	RelA SpoT domain protein
EXW28_21790	COG1785	Belongs to the alkaline phosphatase family
EXW28_21800	COG2267	carboxylic ester hydrolase activity
EXW28_21835	COG1404	Belongs to the peptidase S8 family
EXW28_21840	COG3186	Phenylalanine-4-hydroxylase
EXW28_21845	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW28_21850	COG2514	catechol 2,3-dioxygenase activity
EXW28_21855	COG2259	Doxx family
EXW28_21895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW28_21905	COG1012	belongs to the aldehyde dehydrogenase family
EXW28_21905	COG1454	alcohol dehydrogenase
EXW28_21910	COG0626	cystathionine gamma-synthase activity
EXW28_21915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW28_21920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW28_21925	COG2226	methyltransferase
EXW28_21940	COG0768	penicillin binding
EXW28_21945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW28_21950	COG0572	uridine kinase
EXW28_21955	COG0826	peptidase U32
EXW28_21960	COG0826	peptidase U32
EXW28_21965	COG4122	O-methyltransferase activity
EXW28_21970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW28_21980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW28_21985	COG4472	Bacterial protein of unknown function (DUF965)
EXW28_21990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW28_22000	COG0628	permease
EXW28_22020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW28_22030	COG0482	sulfurtransferase activity
EXW28_22035	COG1104	cysteine desulfurase activity
EXW28_22040	COG1959	2 iron, 2 sulfur cluster binding
EXW28_22045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW28_22060	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW28_22065	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW28_22075	COG1490	D-aminoacyl-tRNA deacylase activity
EXW28_22080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW28_22085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW28_22090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW28_22090	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW28_22095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW28_22100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW28_22100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW28_22110	COG2244	polysaccharide biosynthetic process
EXW28_22115	COG2323	membrane
EXW28_22125	COG1862	Preprotein translocase
EXW28_22130	COG0343	queuine tRNA-ribosyltransferase activity
EXW28_22135	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW28_22145	COG2255	four-way junction helicase activity
EXW28_22150	COG0632	four-way junction helicase activity
EXW28_22155	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW28_22180	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW28_22185	COG0157	Belongs to the NadC ModD family
EXW28_22190	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW28_22195	COG1104	cysteine desulfurase activity
EXW28_22200	COG1827	regulation of RNA biosynthetic process
EXW28_22205	COG2258	MOSC domain
EXW28_22210	COG0077	Prephenate dehydratase
EXW28_22215	COG0577	efflux transmembrane transporter activity
EXW28_22220	COG0577	efflux transmembrane transporter activity
EXW28_22225	COG1136	(ABC) transporter
EXW28_22230	COG5002	protein histidine kinase activity
EXW28_22235	COG0745	RESPONSE REGULATOR receiver
EXW28_22240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW28_22245	COG3290	protein histidine kinase activity
EXW28_22255	COG2868	ribosomal protein
EXW28_22265	COG1530	ribonuclease E activity
EXW28_22270	COG1994	Peptidase M50
EXW28_22275	COG0739	heme binding
EXW28_22280	COG2894	cell division
EXW28_22285	COG0850	regulation of cytokinetic process
EXW28_22300	COG1077	Cell shape determining protein MreB Mrl
EXW28_22335	COG2003	Belongs to the UPF0758 family
EXW28_22340	COG0424	maF-like protein
EXW28_22355	COG0285	dihydrofolate synthase activity
EXW28_22370	COG1388	LysM domain
EXW28_22375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW28_22380	COG0113	porphobilinogen synthase activity
EXW28_22385	COG1587	Uroporphyrinogen-III synthase
EXW28_22390	COG0181	hydroxymethylbilane synthase activity
EXW28_22395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW28_22400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW28_22405	COG1846	Transcriptional regulator
EXW28_22410	COG1764	response to oxidative stress
EXW28_22415	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW28_22425	COG1067	ATP-dependent peptidase activity
EXW28_22425	COG0470	DNA polymerase III
EXW28_22435	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW28_22465	COG0622	Phosphoesterase
EXW28_22475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW28_22480	COG5401	PFAM Sporulation and spore germination
EXW28_22490	COG0477	Major facilitator Superfamily
EXW28_22500	COG1309	transcriptional regulator
EXW28_22510	COG2197	response regulator
EXW28_22515	COG2233	PERMEase
EXW28_22520	COG0402	S-adenosylhomocysteine deaminase activity
EXW28_22525	COG1983	PspC domain protein
EXW28_22530	COG1396	sequence-specific DNA binding
EXW28_22535	COG0697	spore germination
EXW28_22545	COG1959	2 iron, 2 sulfur cluster binding
EXW28_22550	COG1668	transmembrane transport
EXW28_22555	COG4152	abc transporter atp-binding protein
EXW28_22560	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW28_22565	COG1360	Flagellar Motor Protein
EXW28_22570	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW28_22580	COG1876	peptidase activity
EXW28_22585	COG0824	Thioesterase
EXW28_22590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW28_22595	COG1053	succinate dehydrogenase
EXW28_22600	COG2009	succinate dehydrogenase
EXW28_22605	COG1719	4-vinyl reductase, 4VR
EXW28_22610	COG0322	excinuclease ABC activity
EXW28_22615	COG3118	belongs to the thioredoxin family
EXW28_22620	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW28_22625	COG2086	electron transfer activity
EXW28_22630	COG1024	Enoyl-CoA hydratase
EXW28_22635	COG1309	transcriptional regulator
EXW28_22640	COG0318	PFAM AMP-dependent synthetase and ligase
EXW28_22670	COG2318	DinB family
EXW28_22695	COG1131	(ABC) transporter
EXW28_22700	COG2205	protein histidine kinase activity
EXW28_22705	COG0745	RESPONSE REGULATOR receiver
EXW28_22710	COG4895	conserved protein (DUF2196)
EXW28_22715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW28_22720	COG2329	Antibiotic biosynthesis monooxygenase
EXW28_22725	COG4509	Sortase family
EXW28_22730	COG1120	ATPase activity
EXW28_22745	COG5386	Cell surface protein
EXW28_22755	COG5386	Cell surface protein
EXW28_22760	COG1114	Component of the transport system for branched-chain amino acids
EXW28_22770	COG1193	negative regulation of DNA recombination
EXW28_22775	COG1796	DNA polymerase
EXW28_22775	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW28_22780	COG1286	toxin biosynthetic process
EXW28_22785	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW28_22790	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW28_22815	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW28_22820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW28_22835	COG1418	mRNA catabolic process
EXW28_22865	COG2814	Major facilitator Superfamily
EXW28_22870	COG1566	PFAM secretion protein HlyD family protein
EXW28_22875	COG1309	transcriptional regulator
EXW28_22880	COG1363	Peptidase, m42
EXW28_22890	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW28_22905	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW28_22915	COG1484	DNA-dependent DNA replication
EXW28_22920	COG3611	Membrane attachment protein
EXW28_22925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW28_22930	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW28_22935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW28_22940	COG0237	dephospho-CoA kinase activity
EXW28_22945	COG1971	Probably functions as a manganese efflux pump
EXW28_22955	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW28_22955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW28_22960	COG5002	protein histidine kinase activity
EXW28_22965	COG0745	RESPONSE REGULATOR receiver
EXW28_22980	COG0039	L-malate dehydrogenase activity
EXW28_22985	COG0538	isocitrate dehydrogenase activity
EXW28_22990	COG0372	Belongs to the citrate synthase family
EXW28_23005	COG0628	permease
EXW28_23010	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW28_23020	COG0205	6-phosphofructokinase activity
EXW28_23030	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW28_23035	COG1725	Transcriptional regulator
EXW28_23040	COG0281	malic enzyme
EXW28_23045	COG0587	DNA-directed DNA polymerase activity
EXW28_23060	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW28_23080	COG4109	DRTGG domain
EXW28_23085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW28_23090	COG0006	proline dipeptidase activity
EXW28_23120	COG0662	Cupin 2, conserved barrel domain protein
EXW28_23125	COG1476	TRANSCRIPTIONal
EXW28_23140	COG1028	Short-chain dehydrogenase reductase Sdr
EXW28_23145	COG0589	response to stress
EXW28_23165	COG0165	Argininosuccinate lyase
EXW28_23170	COG0137	argininosuccinate synthase activity
EXW28_23185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW28_23200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW28_23205	COG0827	DNA restriction-modification system
EXW28_23210	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW28_23215	COG3874	Sporulation protein YtfJ
EXW28_23230	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW28_23240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW28_23255	COG1104	cysteine desulfurase activity
EXW28_23260	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW28_23275	COG1309	transcriptional regulator
EXW28_23280	COG1956	GAF domain-containing protein
EXW28_23285	COG0626	cystathionine gamma-synthase activity
EXW28_23290	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW28_23315	COG1595	DNA-templated transcription, initiation
EXW28_23325	COG0110	maltose O-acetyltransferase activity
EXW28_23330	COG0456	acetyltransferase
EXW28_23335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW28_23340	COG0454	-acetyltransferase
EXW28_23345	COG0517	IMP dehydrogenase activity
EXW28_23350	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW28_23365	COG0745	RESPONSE REGULATOR receiver
EXW28_23370	COG5002	protein histidine kinase activity
EXW28_23375	COG0666	response to abiotic stimulus
EXW28_23385	COG1970	mechanosensitive ion channel activity
EXW28_23405	COG1609	Transcriptional regulator
EXW28_23415	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW28_23415	COG1605	Chorismate mutase
EXW28_23420	COG4851	CamS sex pheromone cAM373 precursor
EXW28_23425	COG3118	belongs to the thioredoxin family
EXW28_23460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW28_23470	COG1674	ftsk spoiiie
EXW28_23485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW28_23490	COG4848	Belongs to the UPF0354 family
EXW28_23495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW28_23500	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW28_23505	COG1363	Peptidase, m42
EXW28_23515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW28_23520	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW28_23530	COG0510	thiamine kinase activity
EXW28_23535	COG1523	belongs to the glycosyl hydrolase 13 family
EXW28_23545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW28_23550	COG1349	DNA-binding transcription factor activity
EXW28_23555	COG1187	pseudouridine synthase activity
EXW28_23560	COG2244	polysaccharide biosynthetic process
EXW28_23565	COG2081	HI0933 family
EXW28_23570	COG2814	Major facilitator Superfamily
EXW28_23580	COG3832	glyoxalase III activity
EXW28_23600	COG1329	Transcriptional regulator
EXW28_23625	COG0314	molybdopterin synthase activity
EXW28_23630	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW28_23635	COG0303	'Molybdopterin
EXW28_23640	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW28_23645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW28_23650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW28_23675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW28_23685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW28_23725	COG0495	leucyl-tRNA aminoacylation
EXW28_23730	COG2814	Major facilitator Superfamily
EXW28_23735	COG0475	glutathione-regulated potassium exporter activity
EXW28_23740	COG0490	domain, Protein
EXW28_23745	COG0582	viral genome integration into host DNA
EXW28_23760	COG1136	(ABC) transporter
EXW28_23785	COG1242	4 iron, 4 sulfur cluster binding
EXW28_23790	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW28_23800	COG1794	racemase activity, acting on amino acids and derivatives
EXW28_23815	COG2267	carboxylic ester hydrolase activity
EXW28_23820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW28_23825	COG0671	phosphoesterase, PA-phosphatase related
EXW28_23830	COG0438	transferase activity, transferring glycosyl groups
EXW28_23855	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW28_23860	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW28_23885	COG5002	protein histidine kinase activity
EXW28_23890	COG3852	Histidine kinase
EXW28_23895	COG0753	catalase activity
EXW28_23900	COG2267	carboxylic ester hydrolase activity
EXW28_23905	COG1368	sulfuric ester hydrolase activity
EXW28_23910	COG4895	conserved protein (DUF2196)
EXW28_23925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW28_23930	COG1116	anion transmembrane transporter activity
EXW28_23935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW28_23960	COG0494	nUDIX hydrolase
EXW28_24005	COG2076	Multidrug Resistance protein
EXW28_24010	COG2076	Multidrug Resistance protein
EXW28_24015	COG0789	Transcriptional regulator
EXW28_24020	COG1854	S-ribosylhomocysteine lyase activity
EXW28_24030	COG0288	reversible hydration of carbon dioxide
EXW28_24035	COG1271	oxidase subunit
EXW28_24040	COG1294	oxidase, subunit
EXW28_24060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW28_24085	COG1842	Phage shock protein A
EXW28_24115	COG5002	protein histidine kinase activity
EXW28_24120	COG0745	RESPONSE REGULATOR receiver
EXW28_24145	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW28_24150	COG1597	lipid kinase activity
EXW28_24165	COG1136	(ABC) transporter
EXW28_24195	COG5002	protein histidine kinase activity
EXW28_24205	COG0586	Pfam SNARE associated Golgi protein
EXW28_24220	COG0577	efflux transmembrane transporter activity
EXW28_24225	COG1136	(ABC) transporter
EXW28_24230	COG2207	Transcriptional regulator
EXW28_24230	COG3708	Transcriptional regulator
EXW28_24240	COG1131	(ABC) transporter
EXW28_24245	COG5658	integral membrane protein
EXW28_24250	COG0640	Transcriptional regulator
EXW28_24255	COG0745	RESPONSE REGULATOR receiver
EXW28_24260	COG2205	protein histidine kinase activity
EXW28_24265	COG0577	efflux transmembrane transporter activity
EXW28_24270	COG0577	efflux transmembrane transporter activity
EXW28_24275	COG1136	(ABC) transporter
EXW28_24280	COG0577	efflux transmembrane transporter activity
EXW28_24295	COG2188	Transcriptional regulator
EXW28_24315	COG3964	amidohydrolase
EXW28_24335	COG4948	Mandelate Racemase Muconate Lactonizing
EXW28_24340	COG0318	PFAM AMP-dependent synthetase and ligase
EXW28_24345	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW28_24350	COG0596	Alpha beta hydrolase
EXW28_24355	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW28_24360	COG1169	isochorismate synthase
EXW28_24365	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW28_24370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW28_24375	COG1278	Cold shock
EXW28_24395	COG0058	SHG alpha-glucan phosphorylase activity
EXW28_24405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW28_24410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW28_24415	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW28_24430	COG1309	transcriptional regulator
EXW28_24565	COG1285	pathogenesis
EXW28_24570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW28_24580	COG0166	Belongs to the GPI family
EXW28_24590	COG2155	Conserved Protein
EXW28_24595	COG1098	S1 RNA binding domain
EXW28_24600	COG0436	Aminotransferase
EXW28_24605	COG1522	sequence-specific DNA binding
EXW28_24610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW28_24615	COG2267	carboxylic ester hydrolase activity
EXW28_24625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW28_24640	COG5018	Exonuclease
EXW28_24645	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW28_24665	COG2050	protein possibly involved in aromatic compounds catabolism
EXW28_24675	COG1268	BioY protein
EXW28_24680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW28_24685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW28_24695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW28_24700	COG3584	3D domain protein
EXW28_24715	COG1252	NADH dehydrogenase
EXW28_24720	COG0492	ferredoxin-NADP+ reductase activity
EXW28_24740	COG1683	Conserved Protein
EXW28_24765	COG0316	Belongs to the HesB IscA family
EXW28_24770	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW28_24775	COG4844	belongs to the
EXW28_24780	COG1252	NADH dehydrogenase
EXW28_24790	COG0390	transport system, permease component
EXW28_24795	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW28_24835	COG4837	Protein of unknown function (DUF1462)
EXW28_24840	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW28_24850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW28_24855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW28_24880	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW28_24890	COG0647	UMP catabolic process
EXW28_24900	COG2445	Protein of unknown function DUF86
EXW28_24905	COG1494	fructose-1,6-bisphosphatase
EXW28_24920	COG4470	Protein conserved in bacteria
EXW28_24930	COG0789	Transcriptional regulator
EXW28_24935	COG4377	Putative membrane peptidase family (DUF2324)
EXW28_24955	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW28_24960	COG0739	heme binding
EXW28_24970	COG3377	Domain of unknown function (DUF1805)
EXW28_24975	COG0737	Belongs to the 5'-nucleotidase family
EXW28_24980	COG1695	Transcriptional regulator
EXW28_24990	COG0719	Fe-S assembly protein
EXW28_24995	COG0822	iron-sulfur transferase activity
EXW28_25000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW28_25005	COG0719	Fe-S assembly protein
EXW28_25010	COG0396	ATPase activity
EXW28_25015	COG1464	Belongs to the NlpA lipoprotein family
EXW28_25020	COG1464	Belongs to the NlpA lipoprotein family
EXW28_25025	COG2011	ABC-type metal ion transport system permease component
EXW28_25030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW28_25040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW28_25045	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW28_25050	COG0509	glycine decarboxylation via glycine cleavage system
EXW28_25055	COG1393	Belongs to the ArsC family
EXW28_25100	COG1309	transcriptional regulator
EXW28_25105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW28_25110	COG1960	acyl-CoA dehydrogenase activity
EXW28_25115	COG0183	Belongs to the thiolase family
EXW28_25120	COG1024	Enoyl-CoA hydratase
EXW28_25120	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW28_25130	COG1686	Belongs to the peptidase S11 family
EXW28_25135	COG0506	proline dehydrogenase activity
EXW28_25145	COG0011	TIGRFAM Protein of
EXW28_25150	COG0840	transmembrane signaling receptor activity
EXW28_25165	COG2814	Major facilitator Superfamily
EXW28_25170	COG0531	amino acid
EXW28_25195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW28_25230	COG0586	Pfam SNARE associated Golgi protein
EXW28_25240	COG1376	ErfK ybiS ycfS ynhG family protein
EXW28_25245	COG0745	RESPONSE REGULATOR receiver
EXW28_25250	COG5002	protein histidine kinase activity
EXW28_25260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW28_25270	COG0840	transmembrane signaling receptor activity
EXW28_25275	COG0840	transmembrane signaling receptor activity
EXW28_25280	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW28_25285	COG3227	Zinc metalloprotease (Elastase)
EXW28_25290	COG1741	Belongs to the pirin family
EXW28_25305	COG0586	Pfam SNARE associated Golgi protein
EXW28_25310	COG0475	glutathione-regulated potassium exporter activity
EXW28_25315	COG0490	domain, Protein
EXW28_25320	COG1115	amino acid carrier protein
EXW28_25325	COG0783	Belongs to the Dps family
EXW28_25335	COG2318	DinB family
EXW28_25345	COG1611	Belongs to the LOG family
EXW28_25355	COG1528	Iron-storage protein
EXW28_25360	COG2311	Membrane
EXW28_25365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW28_25370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW28_25375	COG1115	amino acid carrier protein
EXW28_25380	COG2910	NAD(P)H-binding
EXW28_25395	COG0656	L-ascorbic acid biosynthetic process
EXW28_25400	COG2814	Major facilitator Superfamily
EXW28_25405	COG1733	regulation of RNA biosynthetic process
EXW28_25415	COG1252	NADH dehydrogenase
EXW28_25435	COG0840	transmembrane signaling receptor activity
EXW28_25435	COG3290	protein histidine kinase activity
EXW28_25470	COG0488	(ABC) transporter
EXW28_25475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW28_25485	COG1733	regulation of RNA biosynthetic process
EXW28_25490	COG0778	Nitroreductase
EXW28_25495	COG4224	UPF0291 protein
EXW28_25500	COG1335	isochorismatase
EXW28_25505	COG1522	sequence-specific DNA binding
EXW28_25515	COG1522	sequence-specific DNA binding
EXW28_25520	COG0288	reversible hydration of carbon dioxide
EXW28_25525	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW28_25530	COG2233	PERMEase
EXW28_25570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW28_25575	COG0557	exoribonuclease II activity
EXW28_25580	COG1647	Serine aminopeptidase, S33
EXW28_25585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW28_25590	COG1346	cytolysis
EXW28_25605	COG0148	phosphopyruvate hydratase activity
EXW28_25615	COG0149	triose-phosphate isomerase activity
EXW28_25620	COG0126	phosphoglycerate kinase activity
EXW28_25625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW28_25640	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW28_25670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW28_25685	COG2323	membrane
EXW28_25700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW28_25705	COG1481	regulation of sporulation
EXW28_25710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW28_25715	COG1660	Displays ATPase and GTPase activities
EXW28_25720	COG1051	belongs to the nudix hydrolase family
EXW28_25730	COG0492	ferredoxin-NADP+ reductase activity
EXW28_25735	COG0457	Tetratricopeptide repeat
EXW28_25740	COG0110	maltose O-acetyltransferase activity
EXW28_25745	COG0546	phosphoglycolate phosphatase activity
EXW28_25750	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW28_25755	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW28_25760	COG1950	PFAM Membrane protein of
EXW28_25765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW28_25770	COG0556	nucleotide-excision repair
EXW28_25785	COG0789	Transcriptional regulator
EXW28_25820	COG0583	DNA-binding transcription factor activity
EXW28_25825	COG0789	Transcriptional regulator
EXW28_25830	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW28_25835	COG0488	(ABC) transporter
EXW28_25845	COG1132	(ABC) transporter
EXW28_25850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW28_25855	COG0793	Belongs to the peptidase S41A family
EXW28_25855	COG3409	Peptidoglycan-binding domain 1 protein
EXW28_25860	COG2177	Part of the ABC transporter FtsEX involved in
EXW28_25865	COG2884	Cell division ATP-binding protein ftsE
EXW28_25900	COG1131	(ABC) transporter
EXW28_25930	COG1278	Cold shock
EXW28_25935	COG1040	competence protein
EXW28_25940	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW28_25945	COG1388	LysM domain
EXW28_25945	COG0791	NLP P60 protein
EXW28_25950	COG1733	regulation of RNA biosynthetic process
EXW28_25955	COG1307	EDD domain protein, DegV family
EXW28_25960	COG1739	Uncharacterized protein family UPF0029
EXW28_25965	COG1316	TRANSCRIPTIONal
EXW28_25970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW28_25975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW28_25980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW28_25990	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW28_25990	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW28_26010	COG1486	melibiose metabolic process
EXW28_26015	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW28_26020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW28_26040	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW28_26050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW28_26055	COG1301	dicarboxylic acid transport
EXW28_26070	COG1511	domain protein
EXW28_26075	COG0583	DNA-binding transcription factor activity
EXW28_26080	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW28_26085	COG1271	oxidase subunit
EXW28_26090	COG1294	oxidase, subunit
EXW28_26095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW28_26100	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW28_26105	COG1620	l-lactate permease
EXW28_26115	COG2389	metal-binding protein
EXW28_26130	COG1368	sulfuric ester hydrolase activity
EXW28_26140	COG1388	LysM domain
EXW28_26140	COG0791	NLP P60 protein
EXW28_26145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW28_26155	COG1215	transferase activity, transferring glycosyl groups
EXW28_26160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW28_26170	COG3584	3D domain protein
EXW28_26170	COG1388	LysM domain
EXW28_26195	COG4715	Zinc finger, swim domain protein
EXW28_26200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW28_26240	COG0577	efflux transmembrane transporter activity
EXW28_26245	COG1136	(ABC) transporter
EXW28_26280	COG3850	Histidine kinase
EXW28_26280	COG5002	protein histidine kinase activity
EXW28_26285	COG0745	RESPONSE REGULATOR receiver
EXW28_26290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW28_26305	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW28_26320	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW28_26350	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW28_26365	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW28_26380	COG0110	maltose O-acetyltransferase activity
EXW28_26405	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW28_26410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW28_26415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW28_26420	COG4464	protein tyrosine phosphatase activity
EXW28_26425	COG0489	protein tyrosine kinase activity
EXW28_26430	COG3944	biosynthesis protein
EXW28_26435	COG0489	protein tyrosine kinase activity
EXW28_26450	COG1609	Transcriptional regulator
EXW28_26460	COG0739	heme binding
EXW28_26475	COG3279	Response regulator of the LytR AlgR family
EXW28_26480	COG2385	sporulation resulting in formation of a cellular spore
EXW28_26495	COG4836	Membrane
EXW28_26500	COG1007	ATP synthesis coupled electron transport
EXW28_26505	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW28_26510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW28_26515	COG0713	ATP synthesis coupled electron transport
EXW28_26520	COG0839	Belongs to the complex I subunit 6 family
EXW28_26530	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW28_26535	COG0649	NAD binding
EXW28_26540	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW28_26545	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW28_26550	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW28_26555	COG5001	Diguanylate cyclase
EXW28_26555	COG3300	MHYT domain
EXW28_26570	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW28_26575	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW28_26580	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW28_26585	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW28_26590	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW28_26595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW28_26605	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW28_26630	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW28_26640	COG0698	ribose 5-phosphate isomerase
EXW28_26650	COG2190	(PTS) system
EXW28_26655	COG2259	Doxx family
EXW28_26660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW28_26670	COG1971	Probably functions as a manganese efflux pump
EXW28_26675	COG0009	L-threonylcarbamoyladenylate synthase
EXW28_26690	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW28_26695	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW28_26705	COG1435	thymidine kinase activity
EXW28_26720	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW28_26730	COG1494	fructose-1,6-bisphosphatase
EXW28_26750	COG4821	SIS domain
EXW28_26755	COG0504	CTP synthase activity
EXW28_26760	COG3343	RNA polymerase activity
EXW28_26770	COG1960	acyl-CoA dehydrogenase activity
EXW28_26775	COG1960	acyl-CoA dehydrogenase activity
EXW28_26780	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW28_26785	COG0183	Belongs to the thiolase family
EXW28_26790	COG2181	nitrate reductase activity
EXW28_26790	COG0247	lactate metabolic process
EXW28_26795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW28_26800	COG4294	response to UV
EXW28_26805	COG5001	Diguanylate cyclase
EXW28_26805	COG3300	MHYT domain
EXW28_26830	COG2197	response regulator
EXW28_26835	COG4585	Histidine kinase
EXW28_26840	COG0842	Transport permease protein
EXW28_26845	COG1131	(ABC) transporter
EXW28_26850	COG0024	Methionine aminopeptidase
EXW28_26860	COG2234	aminopeptidase activity
EXW28_26875	COG4506	Protein conserved in bacteria
EXW28_26880	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW28_26900	COG0010	Belongs to the arginase family
EXW28_26905	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW28_26910	COG2814	Major facilitator Superfamily
EXW28_26915	COG0789	Transcriptional regulator
EXW28_26920	COG0584	glycerophosphoryl diester phosphodiesterase
EXW28_26925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW28_26935	COG1994	Peptidase M50
EXW28_26945	COG1078	dGTPase activity
EXW28_26950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW28_26955	COG1120	ATPase activity
EXW28_26960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW28_26965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW28_26970	COG4844	belongs to the
EXW28_26990	COG0280	phosphate acetyltransferase
EXW28_26995	COG3253	May function as heme-dependent peroxidase
EXW28_27005	COG3773	Cell wall hydrolase
EXW28_27015	COG2363	Small membrane protein
EXW28_27030	COG2233	PERMEase
EXW28_27035	COG0561	phosphatase activity
EXW28_27040	COG2814	Major facilitator Superfamily
EXW28_27045	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW28_27050	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW28_27055	COG1131	(ABC) transporter
EXW28_27060	COG2755	lipolytic protein G-D-S-L family
EXW28_27065	COG1609	Transcriptional regulator
EXW28_27075	COG0460	homoserine dehydrogenase
EXW28_27080	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW28_27085	COG2873	o-acetylhomoserine
EXW28_27100	COG2197	response regulator
EXW28_27105	COG4585	Histidine kinase
EXW28_27105	COG2203	Gaf domain
EXW28_27110	COG0351	phosphomethylpyrimidine kinase
EXW28_27115	COG3706	GGDEF domain
EXW28_27120	COG2879	small protein
EXW28_27125	COG1966	Carbon starvation protein
EXW28_27130	COG3279	Response regulator of the LytR AlgR family
EXW28_27135	COG0477	Major facilitator Superfamily
EXW28_27165	COG0840	transmembrane signaling receptor activity
EXW28_27175	COG1607	acyl-coa hydrolase
EXW28_27185	COG1216	Glycosyl transferase, family 2
EXW28_27190	COG0488	(ABC) transporter
EXW28_27205	COG0463	Glycosyl transferase, family 2
EXW28_27210	COG1309	transcriptional regulator
EXW28_27215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW28_27220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW28_27220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW28_27225	COG0628	permease
EXW28_27235	COG1380	Effector of murein hydrolase LrgA
EXW28_27240	COG3279	Response regulator of the LytR AlgR family
EXW28_27245	COG3275	phosphorelay sensor kinase activity
EXW28_27250	COG2814	Major facilitator Superfamily
EXW28_27255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW28_27260	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW28_27270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW28_27320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW28_27325	COG1272	protein, Hemolysin III
EXW28_27350	COG1164	Oligoendopeptidase f
EXW28_27360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW28_27370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW28_27375	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW28_27380	COG4853	Protein conserved in bacteria
EXW28_27390	COG5002	protein histidine kinase activity
EXW28_27395	COG0745	RESPONSE REGULATOR receiver
EXW28_27425	COG0305	Participates in initiation and elongation during chromosome replication
EXW28_27430	COG0359	binds to the 23S rRNA
EXW28_27435	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW28_27440	COG4241	membrane
EXW28_27450	COG0629	single-stranded DNA binding
EXW28_27455	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW28_27460	COG0012	GTP binding
EXW28_27465	COG4481	Protein conserved in bacteria
EXW28_27470	COG0668	transmembrane transport
EXW28_27480	COG1475	DNA binding
EXW28_27485	COG1192	Involved in chromosome partitioning
EXW28_27490	COG1475	DNA binding
EXW28_27495	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW28_27500	COG0445	tRNA wobble uridine modification
EXW28_27505	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW28_27510	COG1847	R3H domain protein
EXW28_27515	COG0706	membrane insertase activity
EXW28_27520	COG0594	ribonuclease P activity
EXW28_27525	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW28_27585	COG1192	Involved in chromosome partitioning
EXW28_27605	COG0577	efflux transmembrane transporter activity
EXW28_27610	COG1136	(ABC) transporter
EXW28_27625	COG3402	PFAM membrane-flanked domain
EXW28_27710	COG1923	regulation of RNA biosynthetic process
EXW28_27725	COG2188	Transcriptional regulator
EXW28_27745	COG1674	ftsk spoiiie
EXW28_27805	COG0457	Tetratricopeptide repeat
EXW28_27840	COG1396	sequence-specific DNA binding
EXW28_27930	COG0791	NLP P60 protein
EXW28_27930	COG3883	PFAM NLP P60 protein
EXW28_28045	COG1780	Probably involved in ribonucleotide reductase function
EXW28_28065	COG0582	viral genome integration into host DNA
EXW28_28110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW28_28165	COG5002	protein histidine kinase activity
EXW28_28200	COG0778	Nitroreductase
EXW28_28225	COG0384	phenazine biosynthesis protein PhzF
EXW28_28230	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EXW28_28250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW28_28265	COG1674	ftsk spoiiie
EXW28_28280	COG0741	lytic transglycosylase activity
EXW28_28285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW28_28420	COG0367	asparagine synthase
EXW28_28445	COG0463	Glycosyl transferase, family 2
EXW28_28450	COG0463	Glycosyl transferase, family 2
EXW28_28455	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW28_28460	COG1086	Polysaccharide biosynthesis protein
EXW28_28465	COG1088	dTDP-glucose 4,6-dehydratase activity
EXW28_28470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW28_28475	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW28_28490	COG2089	acid synthase
EXW28_28495	COG4641	Protein conserved in bacteria
EXW28_28575	COG0745	RESPONSE REGULATOR receiver
EXW28_28580	COG2205	protein histidine kinase activity
EXW28_28595	COG1136	(ABC) transporter
EXW28_28600	COG0577	efflux transmembrane transporter activity
EXW28_28610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW28_28610	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW28_28635	COG1136	(ABC) transporter
EXW28_28700	COG1115	amino acid carrier protein
EXW28_28710	COG1114	Component of the transport system for branched-chain amino acids
EXW28_28715	COG3409	Peptidoglycan-binding domain 1 protein
EXW28_28715	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW28_28720	COG2239	Acts as a magnesium transporter
EXW28_28725	COG0772	Belongs to the SEDS family
EXW28_28735	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW28_28750	COG0697	spore germination
EXW28_28760	COG1252	NADH dehydrogenase
EXW28_28765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW28_28765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW28_28770	COG2002	toxin-antitoxin pair type II binding
EXW28_28780	COG1923	regulation of RNA biosynthetic process
EXW28_28835	COG2814	Major facilitator Superfamily
EXW28_28860	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW28_28870	COG2002	toxin-antitoxin pair type II binding
EXW28_28925	COG2031	fatty acid transporter
EXW28_28935	COG2312	Erythromycin esterase
EXW28_28965	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW28_28990	COG1388	LysM domain
EXW28_28990	COG3103	Sh3 type 3 domain protein
EXW28_28990	COG0791	NLP P60 protein
EXW28_29010	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW28_29025	COG0583	DNA-binding transcription factor activity
EXW28_29030	COG0768	penicillin binding
EXW28_29040	COG4990	cell redox homeostasis
EXW28_29045	COG0745	RESPONSE REGULATOR receiver
EXW28_29050	COG5002	protein histidine kinase activity
EXW28_29065	COG0745	RESPONSE REGULATOR receiver
EXW28_29095	COG0833	amino acid
EXW28_29100	COG1285	pathogenesis
EXW28_29110	COG2267	carboxylic ester hydrolase activity
EXW28_29125	COG0840	transmembrane signaling receptor activity
EXW28_29165	COG0083	homoserine kinase activity
EXW28_29195	COG4974	Belongs to the 'phage' integrase family
EXW28_29210	COG2333	competence protein COMEC
EXW28_29210	COG0658	competence protein
EXW28_29265	COG2423	ornithine cyclodeaminase activity
EXW28_29275	COG2175	clavaminate synthase activity
EXW28_29280	COG0137	argininosuccinate synthase activity
EXW28_29295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW28_29300	COG0251	oxidation-reduction process
EXW28_29310	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW28_29315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW28_29320	COG1960	acyl-CoA dehydrogenase activity
EXW28_29345	COG0556	nucleotide-excision repair
EXW28_29350	COG0039	L-malate dehydrogenase activity
EXW28_29370	COG0436	Aminotransferase
EXW28_29410	COG0492	ferredoxin-NADP+ reductase activity
EXW28_29425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW28_29425	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EXW28_29435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW28_29440	COG1960	acyl-CoA dehydrogenase activity
EXW28_29455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW28_29465	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EXW28_29495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW28_29505	COG0438	transferase activity, transferring glycosyl groups
EXW28_29510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW28_29515	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW28_29530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW28_29540	COG1131	(ABC) transporter
EXW28_29555	COG2378	regulation of single-species biofilm formation
EXW28_29595	COG2002	toxin-antitoxin pair type II binding
EXW28_29665	COG2814	Major facilitator Superfamily
EXW28_29670	COG0583	DNA-binding transcription factor activity
EXW28_29745	COG2357	RelA SpoT domain protein
EXW28_29750	COG2814	Major facilitator Superfamily
EXW28_29760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW28_29840	COG1725	Transcriptional regulator
EXW28_29845	COG1131	(ABC) transporter
EXW28_29885	COG1329	Transcriptional regulator
EXW28_29920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW28_29925	COG4974	Belongs to the 'phage' integrase family
EXW28_29930	COG0024	Methionine aminopeptidase