locus-tag	class	description
JG486_00035	COG1114	Component of the transport system for branched-chain amino acids
JG486_00055	COG4758	membrane
JG486_00070	COG1757	Na H antiporter
JG486_00095	COG0733	neurotransmitter:sodium symporter activity
JG486_00100	COG1648	precorrin-2 dehydrogenase activity
JG486_00120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JG486_00125	COG0529	Catalyzes the synthesis of activated sulfate
JG486_00135	COG0175	sulfate reduction
JG486_00145	COG0019	diaminopimelate decarboxylase activity
JG486_00160	COG1183	phosphatidylcholine synthase activity
JG486_00175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JG486_00180	COG0140	phosphoribosyl-ATP diphosphatase activity
JG486_00190	COG0107	imidazoleglycerol-phosphate synthase activity
JG486_00195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JG486_00200	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JG486_00205	COG0131	Imidazoleglycerol-phosphate dehydratase
JG486_00215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JG486_00220	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JG486_00230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JG486_00240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JG486_00250	COG0440	acetolactate synthase activity
JG486_00255	COG0028	Belongs to the TPP enzyme family
JG486_00260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JG486_00285	COG3874	Sporulation protein YtfJ
JG486_00295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JG486_00300	COG1301	dicarboxylic acid transport
JG486_00310	COG1846	Transcriptional regulator
JG486_00330	COG1968	undecaprenyl-diphosphatase activity
JG486_00335	COG0534	Mate efflux family protein
JG486_00370	COG0716	FMN binding
JG486_00395	COG1696	Membrane protein involved in D-alanine export
JG486_00400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JG486_00405	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JG486_00410	COG2070	2-Nitropropane dioxygenase
JG486_00415	COG1619	proteins homologs of microcin C7 resistance protein MccF
JG486_00425	COG1335	isochorismatase
JG486_00435	COG1522	sequence-specific DNA binding
JG486_00445	COG1266	CAAX protease self-immunity
JG486_00450	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JG486_00455	COG1131	(ABC) transporter
JG486_00470	COG1725	Transcriptional regulator
JG486_00480	COG1012	belongs to the aldehyde dehydrogenase family
JG486_00490	COG2204	response regulator
JG486_00505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JG486_00510	COG0531	amino acid
JG486_00515	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JG486_00530	COG1780	Probably involved in ribonucleotide reductase function
JG486_00560	COG4873	Protein conserved in bacteria
JG486_00565	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JG486_00575	COG0720	synthase
JG486_00580	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JG486_00585	COG5002	protein histidine kinase activity
JG486_00590	COG2318	DinB family
JG486_00600	COG1846	Transcriptional regulator
JG486_00605	COG3852	Histidine kinase
JG486_00615	COG2861	carbohydrate metabolic process
JG486_00625	COG0235	Class ii aldolase
JG486_00645	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JG486_00650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JG486_00665	COG1840	ABC-type Fe3 transport system, periplasmic component
JG486_00680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JG486_00695	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_00715	COG2030	dehydratase
JG486_00725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JG486_00735	COG0861	Integral membrane protein TerC family
JG486_00740	COG2116	formate transmembrane transporter activity
JG486_00750	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JG486_00755	COG1556	Lactate utilization protein
JG486_00760	COG1139	Iron-sulfur cluster binding protein
JG486_00765	COG0247	lactate metabolic process
JG486_00770	COG2186	Transcriptional regulator
JG486_00775	COG5002	protein histidine kinase activity
JG486_00780	COG0745	RESPONSE REGULATOR receiver
JG486_00800	COG0247	lactate metabolic process
JG486_00805	COG2340	Cysteine-rich secretory protein family
JG486_00815	COG0564	pseudouridine synthase activity
JG486_00825	COG2409	Drug exporters of the RND superfamily
JG486_00835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JG486_00840	COG1177	transmembrane transport
JG486_00845	COG1176	ABC-type spermidine putrescine transport system, permease component I
JG486_00855	COG1012	belongs to the aldehyde dehydrogenase family
JG486_00890	COG0681	Belongs to the peptidase S26 family
JG486_00895	COG1686	Belongs to the peptidase S11 family
JG486_00915	COG1668	transmembrane transport
JG486_00920	COG4152	abc transporter atp-binding protein
JG486_00945	COG1476	TRANSCRIPTIONal
JG486_00950	COG0567	Dehydrogenase, E1 component
JG486_00975	COG2226	methyltransferase
JG486_01025	COG1620	l-lactate permease
JG486_01035	COG0159	tryptophan synthase activity
JG486_01045	COG0135	phosphoribosylanthranilate isomerase activity
JG486_01050	COG0134	indole-3-glycerol-phosphate synthase activity
JG486_01055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JG486_01060	COG0512	Glutamine amidotransferase of anthranilate synthase
JG486_01060	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JG486_01070	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JG486_01075	COG5492	domain, Protein
JG486_01080	COG5492	domain, Protein
JG486_01105	COG2382	esterase
JG486_01110	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JG486_01115	COG2153	protein acetylation
JG486_01175	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JG486_01195	COG0463	Glycosyl transferase, family 2
JG486_01195	COG0457	Tetratricopeptide repeat
JG486_01215	COG1216	Glycosyl transferase, family 2
JG486_01225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JG486_01235	COG0564	pseudouridine synthase activity
JG486_01245	COG2357	RelA SpoT domain protein
JG486_01255	COG4116	CYTH
JG486_01260	COG2346	COG2346, Truncated hemoglobins
JG486_01270	COG1164	Oligoendopeptidase f
JG486_01280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JG486_01290	COG0861	Integral membrane protein TerC family
JG486_01305	COG4166	transmembrane transport
JG486_01310	COG0534	Mate efflux family protein
JG486_01315	COG4608	Belongs to the ABC transporter superfamily
JG486_01320	COG0444	Belongs to the ABC transporter superfamily
JG486_01325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JG486_01330	COG0601	transmembrane transport
JG486_01335	COG4166	transmembrane transport
JG486_01345	COG0180	Tryptophanyl-tRNA synthetase
JG486_01360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JG486_01365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JG486_01380	COG2267	carboxylic ester hydrolase activity
JG486_01400	COG0561	phosphatase activity
JG486_01415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JG486_01425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JG486_01430	COG2996	Protein conserved in bacteria
JG486_01435	COG1666	GTP binding
JG486_01450	COG0753	catalase activity
JG486_01485	COG0179	Fumarylacetoacetate (FAA) hydrolase
JG486_01550	COG0398	Pfam SNARE associated Golgi protein
JG486_01555	COG4903	ComK protein
JG486_01565	COG1278	Cold shock
JG486_01575	COG2224	Isocitrate lyase
JG486_01580	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JG486_01605	COG0697	spore germination
JG486_01625	COG0745	RESPONSE REGULATOR receiver
JG486_01630	COG2205	protein histidine kinase activity
JG486_01635	COG2207	Transcriptional regulator
JG486_01635	COG3708	Transcriptional regulator
JG486_01640	COG1595	DNA-templated transcription, initiation
JG486_01650	COG1078	dGTPase activity
JG486_01655	COG1408	metallophosphoesterase
JG486_01685	COG4208	sulfate ABC transporter
JG486_01690	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JG486_01695	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JG486_01710	COG0318	PFAM AMP-dependent synthetase and ligase
JG486_01720	COG0095	Lipoate-protein ligase
JG486_01725	COG1234	tRNA 3'-trailer cleavage
JG486_01735	COG1609	Transcriptional regulator
JG486_01800	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JG486_01805	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JG486_01810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JG486_01815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JG486_01820	COG2329	Antibiotic biosynthesis monooxygenase
JG486_01825	COG3428	Bacterial PH domain
JG486_01830	COG3402	PFAM membrane-flanked domain
JG486_01845	COG3428	Bacterial PH domain
JG486_01850	COG3402	PFAM membrane-flanked domain
JG486_01870	COG1556	Lactate utilization protein
JG486_01880	COG0247	lactate metabolic process
JG486_01895	COG4473	ABC transporter
JG486_01900	COG1131	(ABC) transporter
JG486_01905	COG0537	adenosine 5'-monophosphoramidase activity
JG486_01915	COG1846	Transcriptional regulator
JG486_01930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JG486_01935	COG3973	AAA domain
JG486_01950	COG1595	DNA-templated transcription, initiation
JG486_01955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JG486_01960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JG486_01965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JG486_01970	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JG486_01980	COG2140	Oxalate decarboxylase
JG486_01990	COG2267	carboxylic ester hydrolase activity
JG486_02000	COG0457	Tetratricopeptide repeat
JG486_02005	COG0346	lactoylglutathione lyase activity
JG486_02015	COG3481	metal-dependent phosphohydrolase, HD sub domain
JG486_02025	COG0420	3'-5' exonuclease activity
JG486_02055	COG2197	response regulator
JG486_02075	COG2807	transmembrane transport
JG486_02105	COG5002	protein histidine kinase activity
JG486_02105	COG2205	protein histidine kinase activity
JG486_02105	COG0784	Response regulator, receiver
JG486_02110	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JG486_02115	COG2208	phosphoserine phosphatase activity
JG486_02125	COG1191	sigma factor activity
JG486_02130	COG2172	sigma factor antagonist activity
JG486_02145	COG2261	transglycosylase associated protein
JG486_02150	COG3237	CsbD-like
JG486_02190	COG0662	Cupin 2, conserved barrel domain protein
JG486_02210	COG4085	toxin activity
JG486_02210	COG1525	nuclease
JG486_02210	COG0737	Belongs to the 5'-nucleotidase family
JG486_02230	COG0076	glutamate decarboxylase activity
JG486_02255	COG1335	isochorismatase
JG486_02270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JG486_02285	COG2376	Dihydroxyacetone kinase
JG486_02295	COG2376	Dihydroxyacetone kinase
JG486_02315	COG0640	Transcriptional regulator
JG486_02320	COG2814	Major facilitator Superfamily
JG486_02375	COG1183	phosphatidylcholine synthase activity
JG486_02385	COG0456	acetyltransferase
JG486_02390	COG2723	6-phospho-beta-galactosidase activity
JG486_02395	COG1263	PTS System
JG486_02395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JG486_02395	COG2190	(PTS) system
JG486_02435	COG0477	Major facilitator Superfamily
JG486_02470	COG0305	Participates in initiation and elongation during chromosome replication
JG486_02515	COG1104	cysteine desulfurase activity
JG486_02525	COG0419	ATPase involved in DNA repair
JG486_02570	COG4565	transcriptional regulatory protein
JG486_02575	COG3290	protein histidine kinase activity
JG486_02665	COG0444	Belongs to the ABC transporter superfamily
JG486_02670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JG486_02675	COG0601	transmembrane transport
JG486_02710	COG0579	oxidoreductase
JG486_02730	COG2318	DinB family
JG486_02745	COG1363	Peptidase, m42
JG486_02760	COG1024	Enoyl-CoA hydratase
JG486_02795	COG2244	polysaccharide biosynthetic process
JG486_02800	COG0653	protein targeting
JG486_02805	COG0659	secondary active sulfate transmembrane transporter activity
JG486_02815	COG0318	PFAM AMP-dependent synthetase and ligase
JG486_02820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JG486_02830	COG0561	phosphatase activity
JG486_02835	COG2094	Belongs to the DNA glycosylase MPG family
JG486_02840	COG1216	Glycosyl transferase, family 2
JG486_02845	COG0463	Glycosyl transferase, family 2
JG486_02850	COG3527	Alpha-acetolactate decarboxylase
JG486_02855	COG0028	Belongs to the TPP enzyme family
JG486_02870	COG3679	Belongs to the UPF0342 family
JG486_02875	COG4399	Belongs to the UPF0754 family
JG486_02900	COG1126	abc transporter atp-binding protein
JG486_02905	COG0765	amino acid transport
JG486_02910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JG486_02915	COG1132	(ABC) transporter
JG486_02920	COG1132	(ABC) transporter
JG486_02925	COG1012	belongs to the aldehyde dehydrogenase family
JG486_02930	COG0531	amino acid
JG486_02940	COG0693	protein deglycase activity
JG486_02950	COG2814	Major facilitator Superfamily
JG486_02970	COG1733	regulation of RNA biosynthetic process
JG486_02975	COG2814	Major facilitator Superfamily
JG486_02980	COG1309	transcriptional regulator
JG486_02985	COG2076	Multidrug Resistance protein
JG486_03010	COG1522	sequence-specific DNA binding
JG486_03015	COG0697	spore germination
JG486_03045	COG1263	PTS System
JG486_03045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JG486_03050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JG486_03055	COG1737	Transcriptional regulator
JG486_03065	COG0475	glutathione-regulated potassium exporter activity
JG486_03070	COG0531	amino acid
JG486_03100	COG0586	Pfam SNARE associated Golgi protein
JG486_03130	COG3546	catalase activity
JG486_03135	COG1114	Component of the transport system for branched-chain amino acids
JG486_03150	COG5522	Integral membrane protein (intg_mem_TP0381)
JG486_03160	COG1136	(ABC) transporter
JG486_03165	COG0577	efflux transmembrane transporter activity
JG486_03170	COG3584	3D domain protein
JG486_03170	COG1388	LysM domain
JG486_03195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JG486_03200	COG1447	Phosphotransferase system cellobiose-specific component IIA
JG486_03205	COG3711	transcriptional antiterminator
JG486_03205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JG486_03215	COG2814	Major facilitator Superfamily
JG486_03220	COG0604	alcohol dehydrogenase
JG486_03225	COG1283	sodium-dependent phosphate transmembrane transporter activity
JG486_03235	COG1316	TRANSCRIPTIONal
JG486_03245	COG0730	response to heat
JG486_03250	COG2210	Belongs to the sulfur carrier protein TusA family
JG486_03255	COG0425	Belongs to the sulfur carrier protein TusA family
JG486_03255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JG486_03260	COG0425	Belongs to the sulfur carrier protein TusA family
JG486_03265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JG486_03265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JG486_03270	COG0425	Belongs to the sulfur carrier protein TusA family
JG486_03270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JG486_03275	COG1937	Protein conserved in bacteria
JG486_03300	COG2719	SpoVR family
JG486_03305	COG0778	Nitroreductase
JG486_03355	COG1609	Transcriptional regulator
JG486_03365	COG1621	beta-fructofuranosidase activity
JG486_03370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JG486_03385	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_03390	COG2252	PERMEase
JG486_03395	COG1879	ABC-type sugar transport system periplasmic component
JG486_03400	COG1129	ABC transporter
JG486_03405	COG1172	Belongs to the binding-protein-dependent transport system permease family
JG486_03425	COG1846	Transcriptional regulator
JG486_03430	COG2814	Major facilitator Superfamily
JG486_03435	COG2205	protein histidine kinase activity
JG486_03440	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JG486_03445	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JG486_03450	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JG486_03475	COG0351	phosphomethylpyrimidine kinase
JG486_03480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JG486_03485	COG2022	thiamine diphosphate biosynthetic process
JG486_03490	COG2104	thiamine diphosphate biosynthetic process
JG486_03495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JG486_03500	COG0352	thiamine-phosphate diphosphorylase activity
JG486_03505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JG486_03510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JG486_03515	COG1116	anion transmembrane transporter activity
JG486_03520	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JG486_03540	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JG486_03655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JG486_03665	COG0581	inorganic phosphate transmembrane transporter activity
JG486_03670	COG0573	inorganic phosphate transmembrane transporter activity
JG486_03675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JG486_03685	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JG486_03690	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JG486_03700	COG0531	amino acid
JG486_03705	COG0697	spore germination
JG486_03710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JG486_03725	COG4990	cell redox homeostasis
JG486_03740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JG486_03745	COG1845	cytochrome c oxidase, subunit III
JG486_03755	COG0569	domain protein
JG486_03755	COG0475	glutathione-regulated potassium exporter activity
JG486_03765	COG2153	protein acetylation
JG486_03780	COG2252	PERMEase
JG486_03785	COG1113	amino acid transport
JG486_03800	COG1114	Component of the transport system for branched-chain amino acids
JG486_03805	COG3104	oligopeptide transport
JG486_03825	COG1476	TRANSCRIPTIONal
JG486_03835	COG0840	transmembrane signaling receptor activity
JG486_03865	COG3568	Endonuclease Exonuclease Phosphatase
JG486_03880	COG1063	alcohol dehydrogenase
JG486_03910	COG1879	ABC-type sugar transport system periplasmic component
JG486_03915	COG1172	Belongs to the binding-protein-dependent transport system permease family
JG486_03925	COG1869	D-ribose catabolic process
JG486_03930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JG486_03935	COG1609	Transcriptional regulator
JG486_03940	COG0477	Major facilitator Superfamily
JG486_03945	COG1846	Transcriptional regulator
JG486_03950	COG2271	Major facilitator Superfamily
JG486_03965	COG0659	secondary active sulfate transmembrane transporter activity
JG486_03980	COG5002	protein histidine kinase activity
JG486_03985	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JG486_03990	COG2378	regulation of single-species biofilm formation
JG486_04000	COG0833	amino acid
JG486_04005	COG0765	amino acid transport
JG486_04010	COG0765	amino acid transport
JG486_04015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JG486_04020	COG1126	abc transporter atp-binding protein
JG486_04030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JG486_04045	COG1404	Belongs to the peptidase S8 family
JG486_04060	COG0697	spore germination
JG486_04080	COG0366	Alpha amylase catalytic
JG486_04085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JG486_04085	COG1263	PTS System
JG486_04090	COG2188	Transcriptional regulator
JG486_04095	COG0531	amino acid
JG486_04115	COG0714	Associated with various cellular activities
JG486_04120	COG4548	von Willebrand factor, type A
JG486_04130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JG486_04135	COG0156	8-amino-7-oxononanoate synthase activity
JG486_04150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG486_04155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG486_04160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JG486_04165	COG3104	oligopeptide transport
JG486_04180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JG486_04185	COG1620	l-lactate permease
JG486_04190	COG1027	Aspartate ammonia-lyase
JG486_04195	COG1253	flavin adenine dinucleotide binding
JG486_04200	COG0346	lactoylglutathione lyase activity
JG486_04205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JG486_04210	COG1316	TRANSCRIPTIONal
JG486_04215	COG2720	vancomycin resistance protein
JG486_04235	COG3227	Zinc metalloprotease (Elastase)
JG486_04255	COG2217	Heavy metal translocating P-type atpase
JG486_04260	COG0640	Transcriptional regulator
JG486_04270	COG0531	amino acid
JG486_04290	COG3383	formate dehydrogenase (NAD+) activity
JG486_04295	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JG486_04300	COG0456	acetyltransferase
JG486_04305	COG0745	RESPONSE REGULATOR receiver
JG486_04320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JG486_04325	COG0697	spore germination
JG486_04335	COG0281	malic enzyme
JG486_04340	COG3493	citrate carrier protein
JG486_04345	COG4565	transcriptional regulatory protein
JG486_04350	COG3290	protein histidine kinase activity
JG486_04370	COG5002	protein histidine kinase activity
JG486_04375	COG0745	RESPONSE REGULATOR receiver
JG486_04380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JG486_04390	COG0395	ABC-type sugar transport system, permease component
JG486_04395	COG1175	transmembrane transport
JG486_04400	COG3842	ATPase activity
JG486_04405	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JG486_04430	COG2851	Citrate transporter
JG486_04435	COG4565	transcriptional regulatory protein
JG486_04440	COG3290	protein histidine kinase activity
JG486_04480	COG2766	serine protein kinase
JG486_04490	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JG486_04510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JG486_04515	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JG486_04635	COG0735	belongs to the Fur family
JG486_04640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JG486_04660	COG4555	ABC transporter
JG486_04665	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JG486_04670	COG0070	glutamate synthase
JG486_04670	COG0069	glutamate synthase activity
JG486_04670	COG0067	glutamate synthase
JG486_04675	COG4129	membrane
JG486_04685	COG3557	Belongs to the UPF0374 family
JG486_04700	COG1194	a g-specific adenine glycosylase
JG486_04730	COG2137	regulation of response to DNA damage stimulus
JG486_04735	COG1090	epimerase
JG486_04740	COG1228	amidohydrolase
JG486_04760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JG486_04775	COG0463	Glycosyl transferase, family 2
JG486_04780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JG486_04780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JG486_04790	COG1216	Glycosyl transferase, family 2
JG486_04810	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JG486_04815	COG1263	PTS System
JG486_04815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JG486_04820	COG2066	Belongs to the glutaminase family
JG486_04840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JG486_04845	COG0833	amino acid
JG486_04855	COG3829	transcription factor binding
JG486_04875	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JG486_04895	COG0535	radical SAM domain protein
JG486_04905	COG0387	Pfam Sodium calcium exchanger
JG486_04925	COG0586	Pfam SNARE associated Golgi protein
JG486_04945	COG0697	spore germination
JG486_04950	COG2217	Heavy metal translocating P-type atpase
JG486_04955	COG1295	ribonuclease BN
JG486_04965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JG486_04970	COG4840	Belongs to the UPF0435 family
JG486_04980	COG3853	Toxic anion resistance protein (TelA)
JG486_04990	COG0861	Integral membrane protein TerC family
JG486_04995	COG2310	stress, protein
JG486_05000	COG2310	stress, protein
JG486_05005	COG2310	stress, protein
JG486_05035	COG2270	Major facilitator Superfamily
JG486_05080	COG0488	(ABC) transporter
JG486_05085	COG1116	anion transmembrane transporter activity
JG486_05090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JG486_05095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JG486_05110	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JG486_05115	COG0352	thiamine-phosphate diphosphorylase activity
JG486_05120	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JG486_05215	COG1263	PTS System
JG486_05215	COG2190	(PTS) system
JG486_05215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JG486_05225	COG0277	FAD linked oxidase domain protein
JG486_05240	COG0549	Belongs to the carbamate kinase family
JG486_05265	COG3290	protein histidine kinase activity
JG486_05265	COG0840	transmembrane signaling receptor activity
JG486_05275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JG486_05280	COG0765	amino acid transport
JG486_05290	COG0723	plastoquinol--plastocyanin reductase activity
JG486_05290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JG486_05300	COG3541	Predicted nucleotidyltransferase
JG486_05320	COG5002	protein histidine kinase activity
JG486_05345	COG0166	Belongs to the GPI family
JG486_05355	COG0492	ferredoxin-NADP+ reductase activity
JG486_05360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JG486_05365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG486_05370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG486_05380	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JG486_05390	COG0450	alkyl hydroperoxide reductase
JG486_05405	COG1473	amidohydrolase
JG486_05410	COG1757	Na H antiporter
JG486_05435	COG4807	Protein conserved in bacteria
JG486_05445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JG486_05455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JG486_05470	COG2309	aminopeptidase activity
JG486_05475	COG2076	Multidrug Resistance protein
JG486_05480	COG1012	belongs to the aldehyde dehydrogenase family
JG486_05490	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JG486_05500	COG1597	lipid kinase activity
JG486_05510	COG0154	amidase activity
JG486_05520	COG4682	membrane
JG486_05525	COG1846	Transcriptional regulator
JG486_05530	COG0003	Pfam Anion-transporting ATPase
JG486_05550	COG2011	ABC-type metal ion transport system permease component
JG486_05560	COG1335	isochorismatase
JG486_05565	COG1012	belongs to the aldehyde dehydrogenase family
JG486_05575	COG4851	CamS sex pheromone cAM373 precursor
JG486_05580	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JG486_05585	COG0210	DNA helicase
JG486_05590	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JG486_05610	COG0151	Belongs to the GarS family
JG486_05615	COG0138	bifunctional purine biosynthesis protein purh
JG486_05620	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JG486_05625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JG486_05630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JG486_05635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JG486_05640	COG0047	phosphoribosylformylglycinamidine synthase activity
JG486_05645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JG486_05650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JG486_05655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JG486_05660	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JG486_05665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JG486_05690	COG0697	spore germination
JG486_05710	COG0745	RESPONSE REGULATOR receiver
JG486_05715	COG2205	protein histidine kinase activity
JG486_05735	COG4187	Peptidase family M20/M25/M40
JG486_05780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JG486_05800	COG5002	protein histidine kinase activity
JG486_05810	COG2252	PERMEase
JG486_05815	COG0519	Catalyzes the synthesis of GMP from XMP
JG486_05815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JG486_05820	COG0459	protein refolding
JG486_05825	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JG486_05830	COG1266	CAAX protease self-immunity
JG486_05840	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JG486_05845	COG0488	(ABC) transporter
JG486_05855	COG0456	acetyltransferase
JG486_05860	COG1214	PFAM Peptidase M22, glycoprotease
JG486_05865	COG0802	atpase or kinase
JG486_05970	COG2337	Toxic component of a toxin-antitoxin (TA) module
JG486_05975	COG0864	Transcriptional regulator
JG486_05985	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JG486_05990	COG0736	holo-[acyl-carrier-protein] synthase activity
JG486_05995	COG0705	Rhomboid family
JG486_06010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JG486_06025	COG0531	amino acid
JG486_06035	COG0179	Fumarylacetoacetate (FAA) hydrolase
JG486_06040	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JG486_06065	COG0561	phosphatase activity
JG486_06070	COG4608	Belongs to the ABC transporter superfamily
JG486_06075	COG0444	Belongs to the ABC transporter superfamily
JG486_06080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JG486_06085	COG0601	transmembrane transport
JG486_06095	COG0747	negative chemotaxis
JG486_06110	COG0842	Transport permease protein
JG486_06110	COG1511	domain protein
JG486_06115	COG1131	(ABC) transporter
JG486_06120	COG2197	response regulator
JG486_06125	COG4585	Histidine kinase
JG486_06130	COG0488	(ABC) transporter
JG486_06165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JG486_06175	COG1609	Transcriptional regulator
JG486_06185	COG0204	Acyl-transferase
JG486_06200	COG0697	spore germination
JG486_06215	COG1910	domain protein
JG486_06220	COG0725	ABC transporter, periplasmic molybdate-binding protein
JG486_06225	COG4149	molybdate abc transporter
JG486_06245	COG0656	L-ascorbic acid biosynthetic process
JG486_06250	COG4166	transmembrane transport
JG486_06255	COG4166	transmembrane transport
JG486_06270	COG2207	Transcriptional regulator
JG486_06285	COG4608	Belongs to the ABC transporter superfamily
JG486_06290	COG0444	Belongs to the ABC transporter superfamily
JG486_06295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JG486_06300	COG0601	transmembrane transport
JG486_06315	COG2814	Major facilitator Superfamily
JG486_06325	COG2271	Major facilitator Superfamily
JG486_06330	COG0277	FAD linked oxidase domain protein
JG486_06340	COG0604	alcohol dehydrogenase
JG486_06345	COG1464	Belongs to the NlpA lipoprotein family
JG486_06355	COG2011	ABC-type metal ion transport system permease component
JG486_06385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JG486_06395	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JG486_06475	COG0726	polysaccharide deacetylase
JG486_06480	COG2194	sulfuric ester hydrolase activity
JG486_06490	COG0489	protein tyrosine kinase activity
JG486_06495	COG0860	N-Acetylmuramoyl-L-alanine amidase
JG486_06505	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JG486_06510	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JG486_06520	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JG486_06545	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JG486_06550	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JG486_06555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JG486_06565	COG0024	Methionine aminopeptidase
JG486_06570	COG0563	adenylate kinase activity
JG486_06580	COG0200	Binds to the 23S rRNA
JG486_06585	COG1841	ribosomal large subunit assembly
JG486_06595	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JG486_06605	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JG486_06615	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JG486_06620	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JG486_06630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JG486_06635	COG0255	Belongs to the universal ribosomal protein uL29 family
JG486_06650	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JG486_06655	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JG486_06660	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JG486_06670	COG0088	Forms part of the polypeptide exit tunnel
JG486_06675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JG486_06680	COG0051	transcription antitermination factor activity, RNA binding
JG486_06685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JG486_06700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JG486_06705	COG1358	cellular component organization or biogenesis
JG486_06710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JG486_06715	COG0085	RNA polymerase activity
JG486_06720	COG2813	Specifically methylates the guanine in position
JG486_06725	COG0222	ribosome binding
JG486_06730	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JG486_06735	COG0081	regulation of translation
JG486_06740	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JG486_06745	COG0250	Participates in transcription elongation, termination and antitermination
JG486_06750	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JG486_06755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JG486_06765	COG3688	RNA-binding protein containing a PIN domain
JG486_06770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JG486_06780	COG0215	cysteine-tRNA ligase activity
JG486_06785	COG1045	serine acetyltransferase
JG486_06790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JG486_06800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JG486_06805	COG4956	integral membrane protein (PIN domain superfamily)
JG486_06810	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JG486_06815	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JG486_06820	COG0542	response to heat
JG486_06825	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JG486_06830	COG3880	PFAM UvrB UvrC protein
JG486_06915	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JG486_06920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JG486_06925	COG1396	sequence-specific DNA binding
JG486_06930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JG486_06935	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JG486_06940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JG486_06945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JG486_06950	COG0512	Glutamine amidotransferase of anthranilate synthase
JG486_06955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JG486_06965	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JG486_06970	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JG486_06975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JG486_06980	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JG486_06990	COG2208	phosphoserine phosphatase activity
JG486_07005	COG1098	S1 RNA binding domain
JG486_07025	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JG486_07030	COG3956	TIGRFAM MazG family protein
JG486_07035	COG2244	polysaccharide biosynthetic process
JG486_07040	COG2002	toxin-antitoxin pair type II binding
JG486_07045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JG486_07065	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JG486_07070	COG2088	sporulation resulting in formation of a cellular spore
JG486_07075	COG0251	oxidation-reduction process
JG486_07085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JG486_07105	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JG486_07115	COG0084	hydrolase, TatD family'
JG486_07125	COG2002	toxin-antitoxin pair type II binding
JG486_07130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JG486_07140	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JG486_07145	COG4467	Involved in initiation control of chromosome replication
JG486_07150	COG1774	PSP1 C-terminal conserved region
JG486_07160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JG486_07165	COG1982	Orn Lys Arg decarboxylase major
JG486_07210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JG486_07215	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JG486_07220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JG486_07235	COG1335	isochorismatase
JG486_07240	COG1428	Deoxynucleoside kinase
JG486_07265	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JG486_07270	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JG486_07275	COG1686	Belongs to the peptidase S11 family
JG486_07280	COG0516	GMP reductase activity
JG486_07280	COG0517	IMP dehydrogenase activity
JG486_07315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JG486_07320	COG0187	DNA topoisomerase II activity
JG486_07330	COG2501	S4 domain
JG486_07335	COG0592	DNA-directed DNA polymerase activity
JG486_07345	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JG486_07350	COG0594	ribonuclease P activity
JG486_07355	COG0706	membrane insertase activity
JG486_07360	COG1847	R3H domain protein
JG486_07375	COG0357	Ribosomal RNA small subunit methyltransferase G
JG486_07385	COG1192	Involved in chromosome partitioning
JG486_07390	COG1475	DNA binding
JG486_07400	COG0668	transmembrane transport
JG486_07405	COG4481	Protein conserved in bacteria
JG486_07415	COG0360	Binds together with S18 to 16S ribosomal RNA
JG486_07420	COG0629	single-stranded DNA binding
JG486_07430	COG4241	membrane
JG486_07435	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JG486_07440	COG0359	binds to the 23S rRNA
JG486_07475	COG0745	RESPONSE REGULATOR receiver
JG486_07480	COG5002	protein histidine kinase activity
JG486_07495	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JG486_07500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JG486_07510	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JG486_07520	COG1164	Oligoendopeptidase f
JG486_07545	COG1272	protein, Hemolysin III
JG486_07550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JG486_07600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JG486_07605	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JG486_07610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JG486_07615	COG2814	Major facilitator Superfamily
JG486_07620	COG3275	phosphorelay sensor kinase activity
JG486_07625	COG3279	Response regulator of the LytR AlgR family
JG486_07630	COG1380	Effector of murein hydrolase LrgA
JG486_07640	COG0628	permease
JG486_07645	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JG486_07645	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JG486_07650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JG486_07655	COG1309	transcriptional regulator
JG486_07665	COG1309	transcriptional regulator
JG486_07675	COG0463	Glycosyl transferase, family 2
JG486_07680	COG4485	Bacterial membrane protein, YfhO
JG486_07690	COG1216	Glycosyl transferase, family 2
JG486_07700	COG1216	Glycosyl transferase, family 2
JG486_07705	COG1607	acyl-coa hydrolase
JG486_07715	COG0840	transmembrane signaling receptor activity
JG486_07740	COG0477	Major facilitator Superfamily
JG486_07745	COG3279	Response regulator of the LytR AlgR family
JG486_07750	COG1966	Carbon starvation protein
JG486_07755	COG2879	small protein
JG486_07760	COG3706	GGDEF domain
JG486_07770	COG2203	Gaf domain
JG486_07770	COG4585	Histidine kinase
JG486_07790	COG2873	o-acetylhomoserine
JG486_07800	COG0460	homoserine dehydrogenase
JG486_07810	COG1609	Transcriptional regulator
JG486_07815	COG2755	lipolytic protein G-D-S-L family
JG486_07820	COG1131	(ABC) transporter
JG486_07825	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JG486_07830	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JG486_07835	COG2814	Major facilitator Superfamily
JG486_07840	COG0561	phosphatase activity
JG486_07845	COG2233	PERMEase
JG486_07860	COG2363	Small membrane protein
JG486_07870	COG3773	Cell wall hydrolase
JG486_07880	COG3253	May function as heme-dependent peroxidase
JG486_07885	COG0280	phosphate acetyltransferase
JG486_07900	COG4844	belongs to the
JG486_07905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG486_07910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG486_07915	COG1120	ATPase activity
JG486_07920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JG486_07925	COG1078	dGTPase activity
JG486_07935	COG1994	Peptidase M50
JG486_07950	COG0584	glycerophosphoryl diester phosphodiesterase
JG486_07955	COG0789	Transcriptional regulator
JG486_07960	COG2814	Major facilitator Superfamily
JG486_07965	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JG486_07985	COG1619	proteins homologs of microcin C7 resistance protein MccF
JG486_07990	COG4506	Protein conserved in bacteria
JG486_08005	COG2234	aminopeptidase activity
JG486_08010	COG0024	Methionine aminopeptidase
JG486_08015	COG1131	(ABC) transporter
JG486_08020	COG0842	Transport permease protein
JG486_08025	COG4585	Histidine kinase
JG486_08030	COG2197	response regulator
JG486_08035	COG3227	Zinc metalloprotease (Elastase)
JG486_08050	COG3300	MHYT domain
JG486_08050	COG5001	Diguanylate cyclase
JG486_08055	COG4294	response to UV
JG486_08065	COG0247	lactate metabolic process
JG486_08065	COG2181	nitrate reductase activity
JG486_08070	COG0183	Belongs to the thiolase family
JG486_08075	COG1250	3-hydroxyacyl-CoA dehydrogenase
JG486_08080	COG1960	acyl-CoA dehydrogenase activity
JG486_08085	COG1960	acyl-CoA dehydrogenase activity
JG486_08095	COG3343	RNA polymerase activity
JG486_08100	COG0504	CTP synthase activity
JG486_08105	COG4821	SIS domain
JG486_08125	COG1494	fructose-1,6-bisphosphatase
JG486_08130	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JG486_08145	COG1435	thymidine kinase activity
JG486_08150	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JG486_08155	COG2890	protein-(glutamine-N5) methyltransferase activity
JG486_08170	COG0009	L-threonylcarbamoyladenylate synthase
JG486_08175	COG1971	Probably functions as a manganese efflux pump
JG486_08185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JG486_08190	COG2259	Doxx family
JG486_08195	COG2190	(PTS) system
JG486_08205	COG0698	ribose 5-phosphate isomerase
JG486_08215	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JG486_08240	COG0356	it plays a direct role in the translocation of protons across the membrane
JG486_08250	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JG486_08255	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JG486_08260	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JG486_08265	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JG486_08270	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JG486_08275	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JG486_08295	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JG486_08305	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JG486_08310	COG0649	NAD binding
JG486_08315	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JG486_08325	COG0839	Belongs to the complex I subunit 6 family
JG486_08330	COG0713	ATP synthesis coupled electron transport
JG486_08335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JG486_08340	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JG486_08345	COG1007	ATP synthesis coupled electron transport
JG486_08350	COG4836	Membrane
JG486_08365	COG2385	sporulation resulting in formation of a cellular spore
JG486_08370	COG3279	Response regulator of the LytR AlgR family
JG486_08385	COG0739	heme binding
JG486_08395	COG1609	Transcriptional regulator
JG486_08410	COG0489	protein tyrosine kinase activity
JG486_08415	COG3944	biosynthesis protein
JG486_08420	COG0489	protein tyrosine kinase activity
JG486_08425	COG4464	protein tyrosine phosphatase activity
JG486_08430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JG486_08455	COG0438	transferase activity, transferring glycosyl groups
JG486_08460	COG1215	transferase activity, transferring glycosyl groups
JG486_08465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JG486_08475	COG1316	TRANSCRIPTIONal
JG486_08485	COG0745	RESPONSE REGULATOR receiver
JG486_08490	COG3850	Histidine kinase
JG486_08490	COG5002	protein histidine kinase activity
JG486_08515	COG1136	(ABC) transporter
JG486_08560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JG486_08565	COG4715	Zinc finger, swim domain protein
JG486_08575	COG3584	3D domain protein
JG486_08575	COG1388	LysM domain
JG486_08580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JG486_08585	COG1215	transferase activity, transferring glycosyl groups
JG486_08595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JG486_08600	COG0791	NLP P60 protein
JG486_08600	COG1388	LysM domain
JG486_08610	COG1368	sulfuric ester hydrolase activity
JG486_08620	COG2389	metal-binding protein
JG486_08630	COG1620	l-lactate permease
JG486_08635	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JG486_08640	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JG486_08645	COG1294	oxidase, subunit
JG486_08660	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JG486_08665	COG0583	DNA-binding transcription factor activity
JG486_08685	COG1301	dicarboxylic acid transport
JG486_08690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JG486_08720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JG486_08725	COG1447	Phosphotransferase system cellobiose-specific component IIA
JG486_08730	COG1486	melibiose metabolic process
JG486_08760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JG486_08770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JG486_08780	COG1739	Uncharacterized protein family UPF0029
JG486_08785	COG1307	EDD domain protein, DegV family
JG486_08790	COG1733	regulation of RNA biosynthetic process
JG486_08795	COG0791	NLP P60 protein
JG486_08795	COG1388	LysM domain
JG486_08800	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JG486_08810	COG1278	Cold shock
JG486_08845	COG1131	(ABC) transporter
JG486_08870	COG2884	Cell division ATP-binding protein ftsE
JG486_08875	COG2177	Part of the ABC transporter FtsEX involved in
JG486_08880	COG0793	Belongs to the peptidase S41A family
JG486_08880	COG3409	Peptidoglycan-binding domain 1 protein
JG486_08885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JG486_08890	COG1132	(ABC) transporter
JG486_08900	COG0488	(ABC) transporter
JG486_08905	COG0655	NAD(P)H dehydrogenase (quinone) activity
JG486_08910	COG0789	Transcriptional regulator
JG486_08915	COG0583	DNA-binding transcription factor activity
JG486_08975	COG1950	PFAM Membrane protein of
JG486_08980	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JG486_08985	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JG486_08990	COG0546	phosphoglycolate phosphatase activity
JG486_08995	COG0110	maltose O-acetyltransferase activity
JG486_09000	COG0457	Tetratricopeptide repeat
JG486_09015	COG1051	belongs to the nudix hydrolase family
JG486_09020	COG1660	Displays ATPase and GTPase activities
JG486_09025	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JG486_09030	COG1481	regulation of sporulation
JG486_09035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JG486_09095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JG486_09110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JG486_09115	COG0126	phosphoglycerate kinase activity
JG486_09120	COG0149	triose-phosphate isomerase activity
JG486_09130	COG0148	phosphopyruvate hydratase activity
JG486_09150	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JG486_09155	COG1647	Serine aminopeptidase, S33
JG486_09160	COG0557	exoribonuclease II activity
JG486_09165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JG486_09185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JG486_09210	COG2233	PERMEase
JG486_09215	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
JG486_09220	COG0288	reversible hydration of carbon dioxide
JG486_09225	COG1522	sequence-specific DNA binding
JG486_09240	COG1335	isochorismatase
JG486_09245	COG4224	UPF0291 protein
JG486_09250	COG0778	Nitroreductase
JG486_09255	COG1733	regulation of RNA biosynthetic process
JG486_09265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JG486_09270	COG0488	(ABC) transporter
JG486_09300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JG486_09330	COG1252	NADH dehydrogenase
JG486_09340	COG1733	regulation of RNA biosynthetic process
JG486_09345	COG2814	Major facilitator Superfamily
JG486_09350	COG0656	L-ascorbic acid biosynthetic process
JG486_09360	COG2910	NAD(P)H-binding
JG486_09365	COG1115	amino acid carrier protein
JG486_09370	COG1115	amino acid carrier protein
JG486_09375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JG486_09380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JG486_09385	COG2311	Membrane
JG486_09390	COG1528	Iron-storage protein
JG486_09400	COG1611	Belongs to the LOG family
JG486_09405	COG2318	DinB family
JG486_09415	COG0783	Belongs to the Dps family
JG486_09420	COG1115	amino acid carrier protein
JG486_09425	COG0490	domain, Protein
JG486_09430	COG0475	glutathione-regulated potassium exporter activity
JG486_09435	COG0586	Pfam SNARE associated Golgi protein
JG486_09450	COG1741	Belongs to the pirin family
JG486_09455	COG3227	Zinc metalloprotease (Elastase)
JG486_09460	COG2151	metal-sulfur cluster biosynthetic enzyme
JG486_09465	COG0840	transmembrane signaling receptor activity
JG486_09480	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JG486_09490	COG5002	protein histidine kinase activity
JG486_09500	COG1376	ErfK ybiS ycfS ynhG family protein
JG486_09510	COG0586	Pfam SNARE associated Golgi protein
JG486_09540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JG486_09570	COG0531	amino acid
JG486_09595	COG0011	TIGRFAM Protein of
JG486_09605	COG0506	proline dehydrogenase activity
JG486_09610	COG1686	Belongs to the peptidase S11 family
JG486_09620	COG1250	3-hydroxyacyl-CoA dehydrogenase
JG486_09620	COG1024	Enoyl-CoA hydratase
JG486_09625	COG0183	Belongs to the thiolase family
JG486_09630	COG1960	acyl-CoA dehydrogenase activity
JG486_09645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JG486_09685	COG1393	Belongs to the ArsC family
JG486_09690	COG0509	glycine decarboxylation via glycine cleavage system
JG486_09695	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JG486_09700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JG486_09710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JG486_09715	COG2011	ABC-type metal ion transport system permease component
JG486_09720	COG1464	Belongs to the NlpA lipoprotein family
JG486_09725	COG1464	Belongs to the NlpA lipoprotein family
JG486_09730	COG0396	ATPase activity
JG486_09735	COG0719	Fe-S assembly protein
JG486_09740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JG486_09745	COG0822	iron-sulfur transferase activity
JG486_09750	COG0719	Fe-S assembly protein
JG486_09760	COG1695	Transcriptional regulator
JG486_09765	COG0737	Belongs to the 5'-nucleotidase family
JG486_09770	COG3377	Domain of unknown function (DUF1805)
JG486_09780	COG0739	heme binding
JG486_09785	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JG486_09805	COG4377	Putative membrane peptidase family (DUF2324)
JG486_09810	COG0789	Transcriptional regulator
JG486_09820	COG4470	Protein conserved in bacteria
JG486_09835	COG1494	fructose-1,6-bisphosphatase
JG486_09840	COG2445	Protein of unknown function DUF86
JG486_09850	COG0647	UMP catabolic process
JG486_09860	COG2249	NAD(P)H dehydrogenase (quinone) activity
JG486_09865	COG0577	efflux transmembrane transporter activity
JG486_09865	COG1136	(ABC) transporter
JG486_09880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JG486_09885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JG486_09895	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JG486_09900	COG4837	Protein of unknown function (DUF1462)
JG486_09930	COG2824	Alkylphosphonate utilization operon protein PhnA
JG486_09935	COG0390	transport system, permease component
JG486_09945	COG1252	NADH dehydrogenase
JG486_09950	COG4844	belongs to the
JG486_09955	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JG486_09980	COG1683	Conserved Protein
JG486_09995	COG3708	Transcriptional regulator
JG486_10000	COG0492	ferredoxin-NADP+ reductase activity
JG486_10005	COG1252	NADH dehydrogenase
JG486_10020	COG3584	3D domain protein
JG486_10025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JG486_10035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JG486_10040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JG486_10050	COG1268	BioY protein
JG486_10060	COG2050	protein possibly involved in aromatic compounds catabolism
JG486_10080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JG486_10085	COG5018	Exonuclease
JG486_10105	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JG486_10115	COG2267	carboxylic ester hydrolase activity
JG486_10120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JG486_10125	COG1522	sequence-specific DNA binding
JG486_10135	COG1098	S1 RNA binding domain
JG486_10140	COG2155	Conserved Protein
JG486_10155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JG486_10160	COG1285	pathogenesis
JG486_10310	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JG486_10325	COG0058	SHG alpha-glucan phosphorylase activity
JG486_10345	COG1278	Cold shock
JG486_10350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JG486_10355	COG1575	Belongs to the MenA family. Type 1 subfamily
JG486_10360	COG1169	isochorismate synthase
JG486_10365	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JG486_10375	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JG486_10385	COG4948	Mandelate Racemase Muconate Lactonizing
JG486_10405	COG3964	amidohydrolase
JG486_10425	COG2188	Transcriptional regulator
JG486_10445	COG1136	(ABC) transporter
JG486_10450	COG0577	efflux transmembrane transporter activity
JG486_10455	COG0577	efflux transmembrane transporter activity
JG486_10460	COG2205	protein histidine kinase activity
JG486_10465	COG0745	RESPONSE REGULATOR receiver
JG486_10470	COG0640	Transcriptional regulator
JG486_10475	COG5658	integral membrane protein
JG486_10485	COG1131	(ABC) transporter
JG486_10495	COG3708	Transcriptional regulator
JG486_10495	COG2207	Transcriptional regulator
JG486_10500	COG1136	(ABC) transporter
JG486_10505	COG0577	efflux transmembrane transporter activity
JG486_10520	COG0586	Pfam SNARE associated Golgi protein
JG486_10560	COG1136	(ABC) transporter
JG486_10595	COG1597	lipid kinase activity
JG486_10600	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JG486_10625	COG0745	RESPONSE REGULATOR receiver
JG486_10635	COG3859	Proton-coupled thiamine transporter YuaJ
JG486_10660	COG1842	Phage shock protein A
JG486_10685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JG486_10715	COG0288	reversible hydration of carbon dioxide
JG486_10725	COG1854	S-ribosylhomocysteine lyase activity
JG486_10730	COG0789	Transcriptional regulator
JG486_10775	COG0494	nUDIX hydrolase
JG486_10800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JG486_10805	COG1116	anion transmembrane transporter activity
JG486_10810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JG486_10845	COG2267	carboxylic ester hydrolase activity
JG486_10855	COG3852	Histidine kinase
JG486_10860	COG5002	protein histidine kinase activity
JG486_10890	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JG486_10895	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JG486_10915	COG0746	molybdenum cofactor guanylyltransferase activity
JG486_10940	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JG486_10945	COG2267	carboxylic ester hydrolase activity
JG486_10970	COG1131	(ABC) transporter
JG486_10975	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JG486_10980	COG1242	4 iron, 4 sulfur cluster binding
JG486_10995	COG1136	(ABC) transporter
JG486_11005	COG0582	viral genome integration into host DNA
JG486_11010	COG0490	domain, Protein
JG486_11015	COG0475	glutathione-regulated potassium exporter activity
JG486_11020	COG2814	Major facilitator Superfamily
JG486_11025	COG0495	leucyl-tRNA aminoacylation
JG486_11065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JG486_11075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JG486_11095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JG486_11100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JG486_11110	COG0303	'Molybdopterin
JG486_11115	COG1763	Mo-molybdopterin cofactor biosynthetic process
JG486_11120	COG0314	molybdopterin synthase activity
JG486_11145	COG1329	Transcriptional regulator
JG486_11165	COG3832	glyoxalase III activity
JG486_11175	COG2814	Major facilitator Superfamily
JG486_11190	COG1187	pseudouridine synthase activity
JG486_11195	COG1349	DNA-binding transcription factor activity
JG486_11200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JG486_11215	COG0510	thiamine kinase activity
JG486_11225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JG486_11230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JG486_11245	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
JG486_11250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JG486_11255	COG4848	Belongs to the UPF0354 family
JG486_11260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JG486_11285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JG486_11290	COG0789	Transcriptional regulator
JG486_11295	COG0697	spore germination
JG486_11325	COG2309	aminopeptidase activity
JG486_11335	COG3118	belongs to the thioredoxin family
JG486_11340	COG4851	CamS sex pheromone cAM373 precursor
JG486_11345	COG1605	Chorismate mutase
JG486_11345	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JG486_11355	COG1609	Transcriptional regulator
JG486_11375	COG1970	mechanosensitive ion channel activity
JG486_11385	COG0666	response to abiotic stimulus
JG486_11395	COG0745	RESPONSE REGULATOR receiver
JG486_11410	COG0123	including yeast histone deacetylase and acetoin utilization protein
JG486_11415	COG0517	IMP dehydrogenase activity
JG486_11420	COG0454	-acetyltransferase
JG486_11425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JG486_11430	COG0456	acetyltransferase
JG486_11435	COG0110	maltose O-acetyltransferase activity
JG486_11445	COG1595	DNA-templated transcription, initiation
JG486_11470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JG486_11475	COG0626	cystathionine gamma-synthase activity
JG486_11480	COG1956	GAF domain-containing protein
JG486_11485	COG1309	transcriptional regulator
JG486_11500	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JG486_11505	COG1104	cysteine desulfurase activity
JG486_11520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JG486_11530	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JG486_11545	COG3874	Sporulation protein YtfJ
JG486_11550	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JG486_11555	COG0827	DNA restriction-modification system
JG486_11560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JG486_11580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JG486_11595	COG0137	argininosuccinate synthase activity
JG486_11600	COG0165	Argininosuccinate lyase
JG486_11620	COG0589	response to stress
JG486_11625	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_11640	COG1476	TRANSCRIPTIONal
JG486_11685	COG0006	proline dipeptidase activity
JG486_11700	COG4109	DRTGG domain
JG486_11715	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JG486_11730	COG0587	DNA-directed DNA polymerase activity
JG486_11735	COG0281	malic enzyme
JG486_11740	COG1725	Transcriptional regulator
JG486_11745	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JG486_11765	COG3030	protein affecting phage T7 exclusion by the F plasmid
JG486_11770	COG0628	permease
JG486_11780	COG0372	Belongs to the citrate synthase family
JG486_11785	COG0538	isocitrate dehydrogenase activity
JG486_11790	COG0039	L-malate dehydrogenase activity
JG486_11805	COG0745	RESPONSE REGULATOR receiver
JG486_11815	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JG486_11815	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JG486_11825	COG1971	Probably functions as a manganese efflux pump
JG486_11830	COG0237	dephospho-CoA kinase activity
JG486_11835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JG486_11840	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JG486_11845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JG486_11850	COG3611	Membrane attachment protein
JG486_11855	COG1484	DNA-dependent DNA replication
JG486_11880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JG486_11890	COG1363	Peptidase, m42
JG486_11895	COG1309	transcriptional regulator
JG486_11900	COG1566	PFAM secretion protein HlyD family protein
JG486_11905	COG2814	Major facilitator Superfamily
JG486_11925	COG1418	mRNA catabolic process
JG486_11935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JG486_11940	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JG486_11965	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JG486_11970	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JG486_11975	COG1286	toxin biosynthetic process
JG486_11980	COG1796	DNA polymerase
JG486_11980	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JG486_11985	COG1193	negative regulation of DNA recombination
JG486_11995	COG1114	Component of the transport system for branched-chain amino acids
JG486_12000	COG5386	Cell surface protein
JG486_12010	COG5386	Cell surface protein
JG486_12030	COG1120	ATPase activity
JG486_12035	COG4509	Sortase family
JG486_12045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JG486_12050	COG4895	conserved protein (DUF2196)
JG486_12060	COG0745	RESPONSE REGULATOR receiver
JG486_12065	COG2205	protein histidine kinase activity
JG486_12070	COG1131	(ABC) transporter
JG486_12095	COG2318	DinB family
JG486_12135	COG0318	PFAM AMP-dependent synthetase and ligase
JG486_12140	COG1309	transcriptional regulator
JG486_12145	COG1024	Enoyl-CoA hydratase
JG486_12150	COG2086	electron transfer activity
JG486_12155	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JG486_12160	COG3118	belongs to the thioredoxin family
JG486_12165	COG0322	excinuclease ABC activity
JG486_12170	COG1719	4-vinyl reductase, 4VR
JG486_12175	COG2009	succinate dehydrogenase
JG486_12180	COG1053	succinate dehydrogenase
JG486_12185	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JG486_12190	COG0824	Thioesterase
JG486_12195	COG1876	peptidase activity
JG486_12210	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JG486_12215	COG4152	abc transporter atp-binding protein
JG486_12225	COG1959	2 iron, 2 sulfur cluster binding
JG486_12240	COG1396	sequence-specific DNA binding
JG486_12250	COG0402	S-adenosylhomocysteine deaminase activity
JG486_12255	COG2233	PERMEase
JG486_12260	COG2197	response regulator
JG486_12275	COG5401	PFAM Sporulation and spore germination
JG486_12280	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JG486_12290	COG0622	Phosphoesterase
JG486_12395	COG0544	peptidyl-prolyl cis-trans isomerase activity
JG486_12405	COG0470	DNA polymerase III
JG486_12405	COG1067	ATP-dependent peptidase activity
JG486_12415	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JG486_12420	COG1764	response to oxidative stress
JG486_12425	COG1846	Transcriptional regulator
JG486_12430	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JG486_12435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JG486_12440	COG0181	hydroxymethylbilane synthase activity
JG486_12450	COG0113	porphobilinogen synthase activity
JG486_12460	COG1388	LysM domain
JG486_12475	COG0285	dihydrofolate synthase activity
JG486_12485	COG0424	maF-like protein
JG486_12495	COG1077	Cell shape determining protein MreB Mrl
JG486_12510	COG0850	regulation of cytokinetic process
JG486_12520	COG0739	heme binding
JG486_12530	COG1530	ribonuclease E activity
JG486_12540	COG2868	ribosomal protein
JG486_12555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JG486_12560	COG0745	RESPONSE REGULATOR receiver
JG486_12565	COG5002	protein histidine kinase activity
JG486_12570	COG1136	(ABC) transporter
JG486_12590	COG2258	MOSC domain
JG486_12595	COG1827	regulation of RNA biosynthetic process
JG486_12600	COG1104	cysteine desulfurase activity
JG486_12605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JG486_12610	COG0157	Belongs to the NadC ModD family
JG486_12615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JG486_12645	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JG486_12650	COG0632	four-way junction helicase activity
JG486_12655	COG2255	four-way junction helicase activity
JG486_12665	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JG486_12670	COG0343	queuine tRNA-ribosyltransferase activity
JG486_12675	COG1862	Preprotein translocase
JG486_12685	COG2323	membrane
JG486_12690	COG2244	polysaccharide biosynthetic process
JG486_12700	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JG486_12700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JG486_12710	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JG486_12710	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JG486_12715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JG486_12720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JG486_12725	COG1490	D-aminoacyl-tRNA deacylase activity
JG486_12745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JG486_12755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JG486_12760	COG1959	2 iron, 2 sulfur cluster binding
JG486_12765	COG1104	cysteine desulfurase activity
JG486_12770	COG0482	sulfurtransferase activity
JG486_12800	COG0628	permease
JG486_12810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JG486_12815	COG4472	Bacterial protein of unknown function (DUF965)
JG486_12820	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JG486_12830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JG486_12835	COG4122	O-methyltransferase activity
JG486_12840	COG0826	peptidase U32
JG486_12845	COG0826	peptidase U32
JG486_12850	COG0572	uridine kinase
JG486_12855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JG486_12860	COG0768	penicillin binding
JG486_12875	COG2226	methyltransferase
JG486_12880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JG486_12890	COG0626	cystathionine gamma-synthase activity
JG486_12895	COG1454	alcohol dehydrogenase
JG486_12895	COG1012	belongs to the aldehyde dehydrogenase family
JG486_12905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JG486_12945	COG2259	Doxx family
JG486_12950	COG2514	catechol 2,3-dioxygenase activity
JG486_12955	COG2154	pterin-4-alpha-carbinolamine dehydratase
JG486_12965	COG1404	Belongs to the peptidase S8 family
JG486_13000	COG2267	carboxylic ester hydrolase activity
JG486_13020	COG2357	RelA SpoT domain protein
JG486_13025	COG1595	DNA-templated transcription, initiation
JG486_13045	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JG486_13050	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JG486_13055	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JG486_13060	COG1534	Rna-binding protein
JG486_13065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JG486_13070	COG1713	HD superfamily hydrolase involved in NAD metabolism
JG486_13075	COG0799	negative regulation of ribosome biogenesis
JG486_13080	COG2226	methyltransferase
JG486_13085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JG486_13095	COG2131	deaminase
JG486_13115	COG0268	Binds directly to 16S ribosomal RNA
JG486_13120	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JG486_13130	COG0481	GTPase activity
JG486_13135	COG1733	regulation of RNA biosynthetic process
JG486_13140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JG486_13145	COG1420	regulation of RNA biosynthetic process
JG486_13170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JG486_13175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JG486_13180	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JG486_13185	COG1610	YqeY-like protein
JG486_13200	COG1702	phosphate starvation-inducible protein PhoH
JG486_13205	COG1480	7TM receptor with intracellular HD hydrolase
JG486_13210	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JG486_13215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JG486_13220	COG0295	cytidine deaminase activity
JG486_13225	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JG486_13235	COG1381	Involved in DNA repair and RecF pathway recombination
JG486_13240	COG0517	IMP dehydrogenase activity
JG486_13245	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JG486_13260	COG0358	DNA primase activity
JG486_13265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JG486_13270	COG2010	Cytochrome c
JG486_13275	COG2384	SAM-dependent methyltransferase
JG486_13280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JG486_13285	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JG486_13300	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JG486_13310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JG486_13315	COG1121	(ABC) transporter
JG486_13325	COG0735	belongs to the Fur family
JG486_13330	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JG486_13355	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JG486_13370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JG486_13375	COG0573	inorganic phosphate transmembrane transporter activity
JG486_13380	COG0581	inorganic phosphate transmembrane transporter activity
JG486_13390	COG0704	Plays a role in the regulation of phosphate uptake
JG486_13395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JG486_13400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JG486_13405	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JG486_13410	COG4483	Protein conserved in bacteria
JG486_13415	COG1940	carbohydrate kinase activity
JG486_13425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JG486_13445	COG0626	cystathionine gamma-synthase activity
JG486_13450	COG0626	cystathionine gamma-synthase activity
JG486_13455	COG0646	methionine synthase
JG486_13455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JG486_13460	COG0646	methionine synthase
JG486_13460	COG1410	methionine synthase
JG486_13515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JG486_13520	COG1459	type II secretion system
JG486_13530	COG4970	Tfp pilus assembly protein FimT
JG486_13555	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JG486_13580	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JG486_13585	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JG486_13595	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JG486_13610	COG1725	Transcriptional regulator
JG486_13650	COG2076	Multidrug Resistance protein
JG486_13655	COG2076	Multidrug Resistance protein
JG486_13665	COG1609	Transcriptional regulator
JG486_13675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JG486_13715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JG486_13725	COG3872	metal-dependent enzyme
JG486_13735	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JG486_13740	COG0006	proline dipeptidase activity
JG486_13765	COG3854	ATPases associated with a variety of cellular activities
JG486_13810	COG0511	ligase activity, forming carbon-carbon bonds
JG486_13815	COG0439	Biotin carboxylase
JG486_13820	COG1302	Protein conserved in bacteria
JG486_13825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JG486_13830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JG486_13840	COG1722	exodeoxyribonuclease VII activity
JG486_13845	COG0142	geranyltranstransferase activity
JG486_13850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JG486_13855	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JG486_13860	COG1438	arginine binding
JG486_13865	COG0497	DNA recombination
JG486_13870	COG0750	zinc metalloprotease
JG486_13875	COG0745	RESPONSE REGULATOR receiver
JG486_13885	COG3093	addiction module antidote protein HigA
JG486_13890	COG0584	glycerophosphoryl diester phosphodiesterase
JG486_13900	COG3829	transcription factor binding
JG486_13900	COG3290	protein histidine kinase activity
JG486_13905	COG0280	phosphate acetyltransferase
JG486_13915	COG3426	butyrate kinase activity
JG486_13920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JG486_13925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JG486_13930	COG0022	dehydrogenase e1 component
JG486_13935	COG0508	dehydrogenase complex catalyzes the overall conversion of
JG486_13940	COG0772	Belongs to the SEDS family
JG486_13945	COG2323	membrane
JG486_13950	COG2816	NAD+ diphosphatase activity
JG486_13960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JG486_13965	COG0765	amino acid transport
JG486_13970	COG1126	abc transporter atp-binding protein
JG486_13975	COG4129	membrane
JG486_13980	COG1376	ErfK ybiS ycfS ynhG family protein
JG486_13995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JG486_14000	COG2195	Cleaves the N-terminal amino acid of tripeptides
JG486_14015	COG1285	pathogenesis
JG486_14025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JG486_14035	COG1234	tRNA 3'-trailer cleavage
JG486_14045	COG1760	l-serine dehydratase
JG486_14050	COG1760	l-serine dehydratase
JG486_14055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JG486_14060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JG486_14065	COG0300	oxidoreductase activity
JG486_14075	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JG486_14110	COG1522	sequence-specific DNA binding
JG486_14125	COG1757	Na H antiporter
JG486_14135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JG486_14145	COG0156	8-amino-7-oxononanoate synthase activity
JG486_14155	COG4106	trans-aconitate 2-methyltransferase activity
JG486_14160	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JG486_14175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JG486_14175	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JG486_14180	COG0307	riboflavin synthase, alpha
JG486_14185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JG486_14185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JG486_14200	COG1073	alpha beta
JG486_14205	COG0456	acetyltransferase
JG486_14210	COG1609	Transcriptional regulator
JG486_14215	COG2056	Na+-H+ antiporter family
JG486_14230	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JG486_14235	COG0737	Belongs to the 5'-nucleotidase family
JG486_14235	COG1525	nuclease
JG486_14235	COG4085	toxin activity
JG486_14245	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JG486_14245	COG0456	acetyltransferase
JG486_14250	COG0656	L-ascorbic acid biosynthetic process
JG486_14275	COG1300	Membrane
JG486_14280	COG0735	belongs to the Fur family
JG486_14290	COG4974	Belongs to the 'phage' integrase family
JG486_14300	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JG486_14330	COG1846	Transcriptional regulator
JG486_14355	COG1725	Transcriptional regulator
JG486_14360	COG1686	Belongs to the peptidase S11 family
JG486_14405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JG486_14420	COG0697	spore germination
JG486_14425	COG0561	phosphatase activity
JG486_14430	COG4086	secreted protein
JG486_14435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JG486_14445	COG1547	Domain of unknown function (DUF309)
JG486_14455	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JG486_14460	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JG486_14475	COG0363	glucosamine-6-phosphate deaminase activity
JG486_14480	COG2188	Transcriptional regulator
JG486_14490	COG3711	transcriptional antiterminator
JG486_14495	COG1263	PTS System
JG486_14495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JG486_14495	COG2190	(PTS) system
JG486_14525	COG2199	diguanylate cyclase activity
JG486_14535	COG2084	Dehydrogenase
JG486_14550	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JG486_14555	COG0235	Class ii aldolase
JG486_14560	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JG486_14570	COG0436	Aminotransferase
JG486_14575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JG486_14580	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JG486_14585	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JG486_14595	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_14600	COG1695	Transcriptional regulator
JG486_14630	COG0183	Belongs to the thiolase family
JG486_14670	COG3842	ATPase activity
JG486_14675	COG0366	Alpha amylase catalytic
JG486_14685	COG2182	Extracellular solute-binding protein
JG486_14690	COG1175	transmembrane transport
JG486_14695	COG3833	ABC-type maltose transport systems, permease component
JG486_14700	COG1609	Transcriptional regulator
JG486_14705	COG0436	Aminotransferase
JG486_14715	COG2205	protein histidine kinase activity
JG486_14725	COG3209	COG3209 Rhs family protein
JG486_14735	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JG486_14745	COG2814	Major facilitator Superfamily
JG486_14790	COG1408	metallophosphoesterase
JG486_14795	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_14800	COG2200	EAL domain
JG486_14815	COG4703	Protein of unknown function (DUF1797)
JG486_14825	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JG486_14835	COG0517	IMP dehydrogenase activity
JG486_14840	COG0583	DNA-binding transcription factor activity
JG486_14845	COG2171	N-acyltransferase activity
JG486_14850	COG1473	amidohydrolase
JG486_14860	COG0569	domain protein
JG486_14865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JG486_14870	COG5503	Protein of unknown function (DUF1447)
JG486_14875	COG0561	phosphatase activity
JG486_14890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JG486_14895	COG0022	dehydrogenase e1 component
JG486_14900	COG0508	dehydrogenase complex catalyzes the overall conversion of
JG486_14945	COG1982	Orn Lys Arg decarboxylase major
JG486_14950	COG4476	Belongs to the UPF0223 family
JG486_14965	COG0483	inositol monophosphate 1-phosphatase activity
JG486_14975	COG1217	gtp-binding protein TYPA
JG486_14990	COG4896	Protein conserved in bacteria
JG486_15000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JG486_15005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JG486_15010	COG4838	Belongs to the UPF0358 family
JG486_15015	COG0772	Belongs to the SEDS family
JG486_15020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JG486_15025	COG1612	heme a metabolic process
JG486_15030	COG0109	protoheme IX farnesyltransferase activity
JG486_15055	COG3336	cytochrome c oxidase
JG486_15065	COG2340	Cysteine-rich secretory protein family
JG486_15080	COG0406	alpha-ribazole phosphatase activity
JG486_15090	COG4471	UPF0298 protein
JG486_15100	COG0742	ribosomal rna small subunit methyltransferase
JG486_15110	COG3314	Sporulation integral membrane protein YlbJ
JG486_15115	COG1752	Esterase of the alpha-beta hydrolase superfamily
JG486_15125	COG1323	Belongs to the UPF0348 family
JG486_15130	COG1399	metal-binding, possibly nucleic acid-binding protein
JG486_15135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JG486_15145	COG0454	-acetyltransferase
JG486_15160	COG0275	rRNA processing
JG486_15175	COG0768	penicillin binding
JG486_15180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JG486_15185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JG486_15190	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JG486_15195	COG0772	Belongs to the SEDS family
JG486_15210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JG486_15215	COG0849	cell division
JG486_15220	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JG486_15230	COG1191	sigma factor activity
JG486_15240	COG1873	PFAM PRC-barrel domain
JG486_15250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JG486_15255	COG1799	cell septum assembly
JG486_15260	COG0762	integral membrane protein
JG486_15265	COG2302	S4 RNA-binding domain
JG486_15270	COG3599	regulation of cell shape
JG486_15285	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JG486_15290	COG0564	pseudouridine synthase activity
JG486_15295	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JG486_15305	COG0540	Belongs to the ATCase OTCase family
JG486_15310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JG486_15320	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JG486_15325	COG0543	2 iron, 2 sulfur cluster binding
JG486_15330	COG0167	dihydroorotate dehydrogenase activity
JG486_15345	COG0546	phosphoglycolate phosphatase activity
JG486_15355	COG3069	C4-dicarboxylate transmembrane transporter activity
JG486_15375	COG0006	proline dipeptidase activity
JG486_15385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JG486_15390	COG1561	YicC-like family, N-terminal region
JG486_15405	COG1758	RNA polymerase activity
JG486_15410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JG486_15415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JG486_15420	COG0242	peptide deformylase activity
JG486_15425	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JG486_15430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JG486_15430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JG486_15435	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JG486_15440	COG0631	protein serine/threonine phosphatase activity
JG486_15445	COG0515	serine threonine protein kinase
JG486_15445	COG2815	serine threonine protein kinase
JG486_15455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JG486_15460	COG1564	THIamine pyrophosphokinase
JG486_15475	COG1302	Protein conserved in bacteria
JG486_15480	COG1461	Dihydroxyacetone kinase
JG486_15485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JG486_15490	COG1349	DNA-binding transcription factor activity
JG486_15490	COG2050	protein possibly involved in aromatic compounds catabolism
JG486_15495	COG0416	fatty acid biosynthetic process
JG486_15500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JG486_15505	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_15510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JG486_15515	COG0571	ribonuclease III activity
JG486_15520	COG1196	nuclear chromosome segregation
JG486_15525	COG0552	protein localization to endoplasmic reticulum
JG486_15545	COG1837	Belongs to the UPF0109 family
JG486_15550	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JG486_15555	COG0336	Belongs to the RNA methyltransferase TrmD family
JG486_15560	COG0335	large ribosomal subunit rRNA binding
JG486_15580	COG0045	succinate-CoA ligase (ADP-forming) activity
JG486_15585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JG486_15590	COG0758	DNA mediated transformation
JG486_15595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JG486_15600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JG486_15605	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JG486_15610	COG4974	Belongs to the 'phage' integrase family
JG486_15615	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JG486_15620	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JG486_15625	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JG486_15635	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JG486_15640	COG0528	UMP kinase activity
JG486_15645	COG0233	cytoplasmic translational termination
JG486_15655	COG4589	Belongs to the CDS family
JG486_15665	COG0750	zinc metalloprotease
JG486_15670	COG0442	prolyl-tRNA aminoacylation
JG486_15680	COG0779	Required for maturation of 30S ribosomal subunits
JG486_15685	COG0195	Participates in both transcription termination and antitermination
JG486_15690	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JG486_15695	COG1358	cellular component organization or biogenesis
JG486_15700	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JG486_15705	COG1550	Protein conserved in bacteria
JG486_15710	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JG486_15720	COG0196	riboflavin kinase activity
JG486_15730	COG1185	polyribonucleotide nucleotidyltransferase activity
JG486_15735	COG0726	polysaccharide deacetylase
JG486_15745	COG1873	PFAM PRC-barrel domain
JG486_15760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JG486_15765	COG0527	aspartate kinase activity
JG486_15775	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JG486_15780	COG0740	serine-type endopeptidase activity
JG486_15790	COG1674	ftsk spoiiie
JG486_15800	COG2188	Transcriptional regulator
JG486_15805	COG1744	ABC transporter substrate-binding protein PnrA-like
JG486_15810	COG3845	ABC transporter
JG486_15815	COG4603	Belongs to the binding-protein-dependent transport system permease family
JG486_15820	COG1079	Belongs to the binding-protein-dependent transport system permease family
JG486_15825	COG0612	Peptidase, M16
JG486_15830	COG0612	Peptidase, M16
JG486_15835	COG0300	oxidoreductase activity
JG486_15855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JG486_15865	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JG486_15870	COG1418	mRNA catabolic process
JG486_15875	COG1692	metallophosphoesterase
JG486_15880	COG2359	stage V sporulation protein S
JG486_15890	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JG486_15890	COG0674	pyruvate-flavodoxin oxidoreductase activity
JG486_15895	COG1013	pyruvate-flavodoxin oxidoreductase activity
JG486_15900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JG486_15905	COG4550	Control of competence regulator ComK, YlbF/YmcA
JG486_15915	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JG486_15920	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JG486_15925	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JG486_15935	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JG486_15945	COG3773	Cell wall hydrolase
JG486_15955	COG2723	6-phospho-beta-galactosidase activity
JG486_15960	COG2188	Transcriptional regulator
JG486_15970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JG486_15975	COG0596	Alpha beta hydrolase
JG486_15975	COG0508	dehydrogenase complex catalyzes the overall conversion of
JG486_15980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JG486_16035	COG0346	lactoylglutathione lyase activity
JG486_16050	COG2195	Cleaves the N-terminal amino acid of tripeptides
JG486_16055	COG2706	6-phosphogluconolactonase activity
JG486_16060	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JG486_16065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JG486_16070	COG2169	Transcriptional regulator
JG486_16075	COG0708	Exodeoxyribonuclease III
JG486_16085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG486_16090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG486_16095	COG1120	ATPase activity
JG486_16100	COG2819	hydrolase of the alpha beta superfamily
JG486_16110	COG4566	intracellular signal transduction
JG486_16140	COG1937	Protein conserved in bacteria
JG486_16145	COG2608	mercury ion transmembrane transporter activity
JG486_16150	COG2217	Heavy metal translocating P-type atpase
JG486_16165	COG2116	formate transmembrane transporter activity
JG486_16185	COG1113	amino acid transport
JG486_16195	COG2322	membrane
JG486_16200	COG1979	alcohol dehydrogenase
JG486_16205	COG1349	DNA-binding transcription factor activity
JG486_16210	COG1105	Belongs to the carbohydrate kinase PfkB family
JG486_16220	COG3584	3D domain protein
JG486_16220	COG1388	LysM domain
JG486_16230	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JG486_16250	COG0464	growth
JG486_16260	COG2860	membrane
JG486_16265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JG486_16270	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JG486_16275	COG0789	Transcriptional regulator
JG486_16280	COG0174	glutamine synthetase
JG486_16295	COG1086	Polysaccharide biosynthesis protein
JG486_16310	COG0463	Glycosyl transferase, family 2
JG486_16310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JG486_16345	COG5434	Belongs to the glycosyl hydrolase 28 family
JG486_16345	COG3420	alginic acid biosynthetic process
JG486_16350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JG486_16355	COG1181	Belongs to the D-alanine--D-alanine ligase family
JG486_16365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JG486_16370	COG0367	asparagine synthase
JG486_16400	COG1132	(ABC) transporter
JG486_16405	COG1695	Transcriptional regulator
JG486_16420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JG486_16425	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JG486_16450	COG3639	organic phosphonate transmembrane transporter activity
JG486_16470	COG3763	UPF0154 protein
JG486_16475	COG1132	(ABC) transporter
JG486_16510	COG0730	response to heat
JG486_16525	COG1346	cytolysis
JG486_16535	COG0583	DNA-binding transcription factor activity
JG486_16545	COG1131	(ABC) transporter
JG486_16565	COG0785	Cytochrome C biogenesis protein
JG486_16570	COG4846	Membrane protein involved in cytochrome C biogenesis
JG486_16595	COG2226	methyltransferase
JG486_16605	COG2986	histidine ammonia-lyase
JG486_16620	COG0010	Belongs to the arginase family
JG486_16635	COG1902	pentaerythritol trinitrate reductase activity
JG486_16640	COG0069	glutamate synthase activity
JG486_16645	COG0346	lactoylglutathione lyase activity
JG486_16650	COG0400	carboxylic ester hydrolase activity
JG486_16660	COG5002	protein histidine kinase activity
JG486_16705	COG0830	nickel cation binding
JG486_16725	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JG486_16750	COG0318	PFAM AMP-dependent synthetase and ligase
JG486_16755	COG1268	BioY protein
JG486_16760	COG0318	PFAM AMP-dependent synthetase and ligase
JG486_16765	COG0183	Belongs to the thiolase family
JG486_16780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JG486_16820	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JG486_16845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JG486_16870	COG0824	Thioesterase
JG486_16875	COG4841	protein insertion into membrane
JG486_16895	COG0745	RESPONSE REGULATOR receiver
JG486_16905	COG1832	CoA-binding protein
JG486_16910	COG0187	DNA topoisomerase II activity
JG486_16915	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JG486_16920	COG0673	inositol 2-dehydrogenase activity
JG486_16940	COG1131	(ABC) transporter
JG486_16955	COG1595	DNA-templated transcription, initiation
JG486_16965	COG1316	TRANSCRIPTIONal
JG486_16970	COG4166	transmembrane transport
JG486_16980	COG4166	transmembrane transport
JG486_16985	COG2226	methyltransferase
JG486_17020	COG0531	amino acid
JG486_17025	COG3326	Membrane
JG486_17030	COG2962	Rard protein
JG486_17035	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JG486_17040	COG1657	PFAM Prenyltransferase squalene oxidase
JG486_17050	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_17055	COG1012	belongs to the aldehyde dehydrogenase family
JG486_17090	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_17110	COG0494	nUDIX hydrolase
JG486_17120	COG0716	FMN binding
JG486_17130	COG1278	Cold shock
JG486_17165	COG0765	amino acid transport
JG486_17170	COG1126	abc transporter atp-binding protein
JG486_17175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JG486_17180	COG2514	catechol 2,3-dioxygenase activity
JG486_17190	COG1285	pathogenesis
JG486_17210	COG0277	FAD linked oxidase domain protein
JG486_17225	COG2808	Putative FMN-binding domain
JG486_17240	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JG486_17245	COG0604	alcohol dehydrogenase
JG486_17250	COG0640	Transcriptional regulator
JG486_17255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JG486_17305	COG3781	membrane
JG486_17325	COG2957	Belongs to the agmatine deiminase family
JG486_17330	COG1164	Oligoendopeptidase f
JG486_17335	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JG486_17345	COG1193	negative regulation of DNA recombination
JG486_17395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG486_17400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG486_17410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JG486_17430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JG486_17435	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JG486_17450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JG486_17455	COG1012	belongs to the aldehyde dehydrogenase family
JG486_17460	COG0534	Mate efflux family protein
JG486_17470	COG1012	belongs to the aldehyde dehydrogenase family
JG486_17485	COG2814	Major facilitator Superfamily
JG486_17495	COG1113	amino acid transport
JG486_17500	COG0604	alcohol dehydrogenase
JG486_17505	COG1695	Transcriptional regulator
JG486_17560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JG486_17585	COG1151	hydroxylamine reductase activity
JG486_17610	COG0814	amino acid
JG486_17655	COG5002	protein histidine kinase activity
JG486_17675	COG2197	response regulator
JG486_17680	COG4585	Histidine kinase
JG486_17705	COG0741	lytic transglycosylase activity
JG486_17745	COG1876	peptidase activity
JG486_17760	COG1191	sigma factor activity
JG486_17775	COG1733	regulation of RNA biosynthetic process
JG486_17785	COG0318	PFAM AMP-dependent synthetase and ligase
JG486_17795	COG0384	phenazine biosynthesis protein PhzF
JG486_17810	COG0494	nUDIX hydrolase
JG486_17835	COG1393	Belongs to the ArsC family
JG486_17855	COG0814	amino acid
JG486_17870	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JG486_17875	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JG486_17885	COG1070	Carbohydrate kinase
JG486_17890	COG2706	6-phosphogluconolactonase activity
JG486_17895	COG3813	Protein conserved in bacteria
JG486_17900	COG1357	PFAM Pentapeptide repeats (8 copies)
JG486_17935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JG486_17945	COG0789	Transcriptional regulator
JG486_17950	COG1253	flavin adenine dinucleotide binding
JG486_17960	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JG486_17975	COG0477	Major facilitator Superfamily
JG486_17985	COG0500	methyltransferase
JG486_17990	COG1720	tRNA m6t6A37 methyltransferase activity
JG486_18005	COG2261	transglycosylase associated protein
JG486_18010	COG0628	permease
JG486_18025	COG0110	maltose O-acetyltransferase activity
JG486_18030	COG0738	Major facilitator superfamily
JG486_18035	COG1940	carbohydrate kinase activity
JG486_18065	COG2365	Tyrosine phosphatase family
JG486_18070	COG1011	Hydrolase
JG486_18085	COG1595	DNA-templated transcription, initiation
JG486_18125	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_18145	COG1733	regulation of RNA biosynthetic process
JG486_18150	COG0778	Nitroreductase
JG486_18155	COG1785	Belongs to the alkaline phosphatase family
JG486_18175	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JG486_18195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JG486_18200	COG2356	endonuclease I
JG486_18205	COG1288	antiporter activity
JG486_18210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JG486_18260	COG2249	NAD(P)H dehydrogenase (quinone) activity
JG486_18270	COG2031	fatty acid transporter
JG486_18285	COG4187	Peptidase family M20/M25/M40
JG486_18410	COG1131	(ABC) transporter
JG486_18425	COG1136	(ABC) transporter
JG486_18515	COG0640	Transcriptional regulator
JG486_18535	COG2814	Major facilitator Superfamily
JG486_18540	COG1846	Transcriptional regulator
JG486_18555	COG0477	Major facilitator Superfamily
JG486_18645	COG5444	nuclease activity
JG486_18710	COG2814	Major facilitator Superfamily
JG486_18745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JG486_18765	COG1619	proteins homologs of microcin C7 resistance protein MccF
JG486_18785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JG486_18795	COG5002	protein histidine kinase activity
JG486_18795	COG3850	Histidine kinase
JG486_18815	COG0577	efflux transmembrane transporter activity
JG486_18820	COG1136	(ABC) transporter
JG486_18835	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JG486_18865	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JG486_18880	COG2814	Major facilitator Superfamily
JG486_18920	COG4977	sequence-specific DNA binding
JG486_18945	COG5002	protein histidine kinase activity
JG486_18975	COG1760	l-serine dehydratase
JG486_18980	COG0814	amino acid
JG486_18990	COG1073	alpha beta
JG486_19020	COG3850	Histidine kinase
JG486_19020	COG5002	protein histidine kinase activity
JG486_19025	COG0745	RESPONSE REGULATOR receiver
JG486_19050	COG0346	lactoylglutathione lyase activity
JG486_19070	COG1522	sequence-specific DNA binding
JG486_19080	COG1309	transcriptional regulator
JG486_19095	COG0640	Transcriptional regulator
JG486_19100	COG0346	lactoylglutathione lyase activity
JG486_19105	COG0798	PFAM Bile acid sodium symporter
JG486_19125	COG1121	(ABC) transporter
JG486_19130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JG486_19135	COG0803	Belongs to the bacterial solute-binding protein 9 family
JG486_19155	COG1575	Belongs to the MenA family. Type 1 subfamily
JG486_19165	COG0745	RESPONSE REGULATOR receiver
JG486_19195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JG486_19205	COG0574	Belongs to the PEP-utilizing enzyme family
JG486_19205	COG3848	Pyruvate phosphate dikinase
JG486_19220	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JG486_19240	COG3314	Sporulation integral membrane protein YlbJ
JG486_19275	COG1960	acyl-CoA dehydrogenase activity
JG486_19295	COG1414	Transcriptional regulator
JG486_19300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JG486_19305	COG1984	allophanate hydrolase subunit 2
JG486_19310	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JG486_19325	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JG486_19330	COG3104	oligopeptide transport
JG486_19345	COG0768	penicillin binding
JG486_19350	COG0681	Belongs to the peptidase S26 family
JG486_19385	COG0833	amino acid
JG486_19395	COG0730	response to heat
JG486_19420	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JG486_19420	COG0456	acetyltransferase
JG486_19500	COG0456	acetyltransferase
JG486_19505	COG2207	Transcriptional regulator
JG486_19535	COG1725	Transcriptional regulator
JG486_19555	COG0494	nUDIX hydrolase
JG486_19570	COG1846	Transcriptional regulator
JG486_19575	COG0778	Nitroreductase
JG486_19610	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JG486_19620	COG0753	catalase activity
JG486_19625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JG486_19645	COG0714	Associated with various cellular activities
JG486_19675	COG0346	lactoylglutathione lyase activity
JG486_19680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JG486_19695	COG3655	Transcriptional regulator
JG486_19705	COG1349	DNA-binding transcription factor activity
JG486_19710	COG1175	transmembrane transport
JG486_19735	COG3842	ATPase activity
JG486_19755	COG3239	Fatty acid desaturase
JG486_19760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JG486_19765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JG486_19775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JG486_19800	COG2329	Antibiotic biosynthesis monooxygenase
JG486_19820	COG2226	methyltransferase
JG486_19840	COG2390	Transcriptional regulator
JG486_19850	COG0579	oxidoreductase
JG486_19880	COG0431	NADPH-dependent FMN reductase
JG486_19890	COG0346	lactoylglutathione lyase activity
JG486_19945	COG1605	Chorismate mutase
JG486_19945	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JG486_19960	COG0287	Prephenate dehydrogenase
JG486_19985	COG1309	transcriptional regulator
JG486_19990	COG1033	growth of symbiont in host cell
JG486_19990	COG2409	Drug exporters of the RND superfamily
JG486_19995	COG0488	(ABC) transporter
JG486_20010	COG1368	sulfuric ester hydrolase activity
JG486_20015	COG2814	Major facilitator Superfamily
JG486_20025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JG486_20075	COG2318	DinB family
JG486_20080	COG0697	spore germination
JG486_20090	COG2746	aminoglycoside 3-N-acetyltransferase activity
JG486_20135	COG0628	permease
JG486_20210	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JG486_20250	COG2226	methyltransferase
JG486_20265	COG2261	transglycosylase associated protein
JG486_20285	COG2814	Major facilitator Superfamily
JG486_20285	COG0477	Major facilitator Superfamily
JG486_20290	COG4533	DNA binding
JG486_20295	COG0789	Transcriptional regulator
JG486_20300	COG1664	Polymer-forming cytoskeletal
JG486_20310	COG2814	Major facilitator Superfamily
JG486_20325	COG1335	isochorismatase
JG486_20350	COG1307	EDD domain protein, DegV family
JG486_20365	COG1522	sequence-specific DNA binding
JG486_20400	COG0745	RESPONSE REGULATOR receiver
JG486_20450	COG0667	Aldo Keto reductase
JG486_20470	COG4948	Mandelate Racemase Muconate Lactonizing
JG486_20480	COG4166	transmembrane transport
JG486_20500	COG0586	Pfam SNARE associated Golgi protein
JG486_20540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JG486_20545	COG3938	Belongs to the proline racemase family
JG486_20555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JG486_20560	COG1012	belongs to the aldehyde dehydrogenase family
JG486_20570	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JG486_20590	COG2318	DinB family
JG486_20595	COG3397	chitin binding
JG486_20610	COG4637	Psort location Cytoplasmic, score
JG486_20635	COG0514	ATP-dependent DNA helicase (RecQ)
JG486_20640	COG2105	PFAM AIG2 family protein
JG486_20705	COG2205	protein histidine kinase activity
JG486_20735	COG3397	chitin binding
JG486_20740	COG2153	protein acetylation
JG486_20745	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JG486_20770	COG0517	IMP dehydrogenase activity
JG486_20770	COG4175	Glycine betaine
JG486_20775	COG4176	ABC-type proline glycine betaine transport system permease component
JG486_20810	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_20830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JG486_20835	COG0022	dehydrogenase e1 component
JG486_20840	COG0508	dehydrogenase complex catalyzes the overall conversion of
JG486_20845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JG486_20860	COG1959	2 iron, 2 sulfur cluster binding
JG486_20880	COG1349	DNA-binding transcription factor activity
JG486_20895	COG3284	Transcriptional regulator
JG486_20910	COG1309	transcriptional regulator
JG486_20915	COG3844	kynureninase activity
JG486_20920	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JG486_20950	COG2959	enzyme of heme biosynthesis
JG486_20965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JG486_21005	COG3386	PFAM SMP-30 Gluconolaconase
JG486_21015	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
JG486_21020	COG3773	Cell wall hydrolase
JG486_21030	COG0745	RESPONSE REGULATOR receiver
JG486_21035	COG2205	protein histidine kinase activity
JG486_21040	COG0583	DNA-binding transcription factor activity
JG486_21045	COG0667	Aldo Keto reductase
JG486_21050	COG0488	(ABC) transporter
JG486_21065	COG0577	efflux transmembrane transporter activity
JG486_21085	COG0460	homoserine dehydrogenase
JG486_21090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JG486_21100	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JG486_21200	COG5002	protein histidine kinase activity
JG486_21220	COG1819	glycosyl
JG486_21225	COG1794	racemase activity, acting on amino acids and derivatives
JG486_21230	COG4720	Psort location CytoplasmicMembrane, score
JG486_21235	COG1122	ATPase activity
JG486_21250	COG2205	protein histidine kinase activity
JG486_21270	COG0745	RESPONSE REGULATOR receiver
JG486_21275	COG5002	protein histidine kinase activity
JG486_21280	COG0604	alcohol dehydrogenase
JG486_21285	COG0671	phosphoesterase, PA-phosphatase related
JG486_21290	COG0768	penicillin binding
JG486_21345	COG0584	glycerophosphoryl diester phosphodiesterase
JG486_21360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JG486_21365	COG0697	spore germination
JG486_21385	COG0494	nUDIX hydrolase
JG486_21395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JG486_21405	COG2223	nitrite transmembrane transporter activity
JG486_21420	COG0592	DNA-directed DNA polymerase activity
JG486_21425	COG1051	belongs to the nudix hydrolase family
JG486_21475	COG4667	esterase of the alpha-beta hydrolase superfamily
JG486_21490	COG2318	DinB family
JG486_21515	COG0322	excinuclease ABC activity
JG486_21540	COG1132	(ABC) transporter
JG486_21550	COG1183	phosphatidylcholine synthase activity
JG486_21555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JG486_21585	COG0745	RESPONSE REGULATOR receiver
JG486_21590	COG5002	protein histidine kinase activity
JG486_21625	COG0577	efflux transmembrane transporter activity
JG486_21640	COG0657	acetylesterase activity
JG486_21645	COG0076	glutamate decarboxylase activity
JG486_21660	COG1523	belongs to the glycosyl hydrolase 13 family
JG486_21665	COG3227	Zinc metalloprotease (Elastase)
JG486_21670	COG0737	Belongs to the 5'-nucleotidase family
JG486_21680	COG0201	protein transport
JG486_21700	COG0697	spore germination
JG486_21705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JG486_21720	COG2323	membrane
JG486_21750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JG486_21755	COG0697	spore germination
JG486_21785	COG1309	transcriptional regulator
JG486_21810	COG1733	regulation of RNA biosynthetic process
JG486_21815	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_21840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JG486_21870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JG486_21900	COG2318	DinB family
JG486_21960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JG486_21965	COG1024	Enoyl-CoA hydratase
JG486_21970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JG486_21975	COG0511	ligase activity, forming carbon-carbon bonds
JG486_21980	COG0439	Biotin carboxylase
JG486_21985	COG1960	acyl-CoA dehydrogenase activity
JG486_21995	COG1309	transcriptional regulator
JG486_22025	COG0823	Involved in the tonB-independent uptake of proteins
JG486_22030	COG3397	chitin binding
JG486_22060	COG0697	spore germination
JG486_22075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JG486_22090	COG2239	Acts as a magnesium transporter
JG486_22155	COG2723	6-phospho-beta-galactosidase activity
JG486_22200	COG1136	(ABC) transporter
JG486_22250	COG1252	NADH dehydrogenase
JG486_22285	COG0768	penicillin binding
JG486_22290	COG0768	penicillin binding
JG486_22300	COG1595	DNA-templated transcription, initiation
JG486_22315	COG1136	(ABC) transporter
JG486_22320	COG2205	protein histidine kinase activity
JG486_22325	COG0745	RESPONSE REGULATOR receiver
JG486_22355	COG1686	Belongs to the peptidase S11 family
JG486_22380	COG1136	(ABC) transporter
JG486_22395	COG2195	Cleaves the N-terminal amino acid of tripeptides
JG486_22430	COG0693	protein deglycase activity
JG486_22445	COG1136	(ABC) transporter
JG486_22460	COG1309	transcriptional regulator
JG486_22520	COG2971	BadF BadG BcrA BcrD
JG486_22525	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JG486_22545	COG1649	PFAM Uncharacterised BCR, COG1649
JG486_22570	COG1595	DNA-templated transcription, initiation
JG486_22575	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
JG486_22610	COG1278	Cold shock
JG486_22720	COG1396	sequence-specific DNA binding
JG486_22745	COG4974	Belongs to the 'phage' integrase family
JG486_22755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JG486_22780	COG1132	(ABC) transporter
JG486_22800	COG2258	MOSC domain
JG486_22805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JG486_22810	COG0583	DNA-binding transcription factor activity
JG486_22825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JG486_22860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JG486_22900	COG1247	-acetyltransferase
JG486_22930	COG1309	transcriptional regulator
JG486_22935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JG486_22945	COG1846	Transcriptional regulator
JG486_23000	COG1253	flavin adenine dinucleotide binding
JG486_23020	COG2226	methyltransferase
JG486_23030	COG0028	Belongs to the TPP enzyme family
JG486_23045	COG0596	Alpha beta hydrolase
JG486_23055	COG1136	(ABC) transporter
JG486_23065	COG3655	Transcriptional regulator
JG486_23070	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JG486_23075	COG1187	pseudouridine synthase activity
JG486_23085	COG2329	Antibiotic biosynthesis monooxygenase
JG486_23100	COG1115	amino acid carrier protein
JG486_23105	COG2318	DinB family
JG486_23115	COG0776	regulation of translation
JG486_23130	COG2814	Major facilitator Superfamily
JG486_23135	COG3251	PFAM MbtH domain protein
JG486_23140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JG486_23145	COG1535	isochorismatase
JG486_23145	COG3433	isochorismatase activity
JG486_23150	COG1021	2,3-dihydroxybenzoate-AMP ligase
JG486_23160	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_23165	COG2223	nitrite transmembrane transporter activity
JG486_23190	COG0420	3'-5' exonuclease activity
JG486_23205	COG1024	Enoyl-CoA hydratase
JG486_23210	COG1280	lysine exporter protein (LysE YggA)
JG486_23215	COG1012	belongs to the aldehyde dehydrogenase family
JG486_23220	COG2084	Dehydrogenase
JG486_23225	COG1960	acyl-CoA dehydrogenase activity
JG486_23230	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JG486_23235	COG2079	MmgE PrpD family protein
JG486_23240	COG0372	Belongs to the citrate synthase family
JG486_23250	COG2814	Major facilitator Superfamily
JG486_23280	COG1028	Short-chain dehydrogenase reductase Sdr
JG486_23305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JG486_23360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JG486_23365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JG486_23370	COG0671	phosphoesterase, PA-phosphatase related
JG486_23380	COG0515	serine threonine protein kinase
JG486_23380	COG4991	sh3 domain protein
JG486_23380	COG3064	Membrane
JG486_23405	COG4479	Belongs to the UPF0346 family
JG486_23415	COG1509	lysine 2,3-aminomutase activity
JG486_23425	COG0456	acetyltransferase
JG486_23430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JG486_23435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JG486_23440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JG486_23445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JG486_23460	COG5506	Protein of unknown function (DUF1694)
JG486_23465	COG1012	belongs to the aldehyde dehydrogenase family
JG486_23470	COG1253	flavin adenine dinucleotide binding
JG486_23530	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JG486_23540	COG1070	Carbohydrate kinase
JG486_23555	COG1064	alcohol dehydrogenase
JG486_23560	COG1737	Transcriptional regulator
JG486_23565	COG2197	response regulator
JG486_23575	COG0668	transmembrane transport
JG486_23585	COG1335	isochorismatase
JG486_23600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JG486_23605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JG486_23610	COG0860	N-Acetylmuramoyl-L-alanine amidase
JG486_23625	COG0367	asparagine synthase
JG486_23630	COG0071	Belongs to the small heat shock protein (HSP20) family
JG486_23635	COG1999	signal sequence binding
JG486_23640	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JG486_23655	COG0805	protein transport
JG486_23660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JG486_23665	COG1272	protein, Hemolysin III
JG486_23670	COG0204	Acyl-transferase
JG486_23680	COG0768	penicillin binding
JG486_23695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JG486_23710	COG0546	phosphoglycolate phosphatase activity
JG486_23720	COG4473	ABC transporter
JG486_23725	COG1131	(ABC) transporter
JG486_23735	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JG486_23740	COG0456	acetyltransferase
JG486_23790	COG0017	Asparaginyl-tRNA synthetase
JG486_23840	COG0018	arginyl-trna synthetase
JG486_23845	COG2136	Putative SAM-dependent methyltransferase
JG486_23845	COG2521	methyltransferase
JG486_23880	COG0488	(ABC) transporter
JG486_23885	COG1418	mRNA catabolic process
JG486_23905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JG486_23910	COG0582	viral genome integration into host DNA
JG486_23955	COG2359	stage V sporulation protein S
JG486_23990	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
JG486_23995	COG0714	Associated with various cellular activities
JG486_24000	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JG486_24010	COG0386	Belongs to the glutathione peroxidase family
JG486_24020	COG0426	domain, Protein
JG486_24020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JG486_24045	COG1595	DNA-templated transcription, initiation
JG486_24050	COG0604	alcohol dehydrogenase
JG486_24060	COG0346	lactoylglutathione lyase activity
JG486_24085	COG2226	methyltransferase
JG486_24110	COG3874	Sporulation protein YtfJ
JG486_24195	COG4499	WXG100 protein secretion system (Wss), protein YukC
JG486_24255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JG486_24260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JG486_24265	COG1819	glycosyl
JG486_24290	COG0561	phosphatase activity
JG486_24300	COG0860	N-Acetylmuramoyl-L-alanine amidase
JG486_24315	COG2211	Major facilitator Superfamily
JG486_24330	COG1876	peptidase activity
JG486_24340	COG0860	N-Acetylmuramoyl-L-alanine amidase
JG486_24360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JG486_24365	COG1114	Component of the transport system for branched-chain amino acids
JG486_24390	COG1253	flavin adenine dinucleotide binding
JG486_24395	COG2839	Protein conserved in bacteria
JG486_24400	COG0702	epimerase
JG486_24415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JG486_24425	COG1607	acyl-coa hydrolase
JG486_24430	COG3689	TIGRFAM TIGR03943 family protein
JG486_24445	COG2244	polysaccharide biosynthetic process
JG486_24450	COG0586	Pfam SNARE associated Golgi protein
JG486_24455	COG1051	belongs to the nudix hydrolase family
JG486_24470	COG0406	alpha-ribazole phosphatase activity
JG486_24480	COG0346	lactoylglutathione lyase activity
JG486_24485	COG4166	transmembrane transport
JG486_24495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JG486_24500	COG1902	pentaerythritol trinitrate reductase activity
JG486_24510	COG0745	RESPONSE REGULATOR receiver
JG486_24515	COG0577	efflux transmembrane transporter activity
JG486_24520	COG1136	(ABC) transporter
JG486_24525	COG2814	Major facilitator Superfamily
JG486_24545	COG0803	Belongs to the bacterial solute-binding protein 9 family
JG486_24550	COG0456	acetyltransferase
JG486_24565	COG0523	cobalamin synthesis protein
JG486_24570	COG4989	oxidoreductase activity
JG486_24575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JG486_24590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JG486_24605	COG0783	Belongs to the Dps family
JG486_24610	COG3949	Membrane
JG486_24615	COG3949	Membrane
JG486_24655	COG2814	Major facilitator Superfamily
JG486_24660	COG0667	Aldo Keto reductase
JG486_24665	COG0640	Transcriptional regulator
JG486_24670	COG1404	Belongs to the peptidase S8 family
JG486_24675	COG2002	toxin-antitoxin pair type II binding
JG486_24680	COG0577	efflux transmembrane transporter activity
JG486_24685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JG486_24725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JG486_24730	COG1279	arginine transmembrane transporter activity
JG486_24735	COG2814	Major facilitator Superfamily
JG486_24745	COG1082	Xylose isomerase domain protein TIM barrel
JG486_24755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JG486_24775	COG1247	-acetyltransferase
JG486_24780	COG1285	pathogenesis
JG486_24800	COG1316	TRANSCRIPTIONal
JG486_24815	COG0083	homoserine kinase activity
JG486_24825	COG0460	homoserine dehydrogenase
JG486_24835	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JG486_24855	COG4122	O-methyltransferase activity
JG486_24860	COG0300	oxidoreductase activity
JG486_24865	COG5002	protein histidine kinase activity
JG486_24870	COG0745	RESPONSE REGULATOR receiver
JG486_24875	COG1132	(ABC) transporter
JG486_24885	COG1388	LysM domain
JG486_24885	COG0791	NLP P60 protein
JG486_24900	COG1686	Belongs to the peptidase S11 family
JG486_24930	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JG486_24935	COG4988	ABC transporter
JG486_24940	COG1294	oxidase, subunit
JG486_24945	COG1271	oxidase subunit
JG486_24955	COG0346	lactoylglutathione lyase activity
JG486_24980	COG0583	DNA-binding transcription factor activity
JG486_25000	COG0411	ABC transporter
JG486_25015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JG486_25020	COG2030	dehydratase
JG486_25025	COG0318	PFAM AMP-dependent synthetase and ligase
JG486_25035	COG0523	cobalamin synthesis protein
JG486_25040	COG1231	oxidoreductase activity
JG486_25055	COG0628	permease
JG486_25065	COG0778	Nitroreductase
JG486_25070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JG486_25075	COG1959	2 iron, 2 sulfur cluster binding
JG486_25080	COG0583	DNA-binding transcription factor activity
JG486_25085	COG0697	spore germination
JG486_25095	COG4549	nuclear export factor GLE1
JG486_25100	COG2372	response to copper ion
JG486_25100	COG1276	copper resistance
JG486_25110	COG4641	Protein conserved in bacteria
JG486_25120	COG1114	Component of the transport system for branched-chain amino acids
JG486_25155	COG0006	proline dipeptidase activity
JG486_25175	COG0583	DNA-binding transcription factor activity
JG486_25190	COG4846	Membrane protein involved in cytochrome C biogenesis
JG486_25205	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JG486_25210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JG486_25215	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JG486_25225	COG2390	Transcriptional regulator
JG486_25230	COG4257	antibiotic catabolic process
JG486_25245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JG486_25280	COG0531	amino acid
JG486_25285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JG486_25300	COG1914	H( )-stimulated, divalent metal cation uptake system
JG486_25310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JG486_25345	COG2814	Major facilitator Superfamily
JG486_25370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JG486_25390	COG0028	Belongs to the TPP enzyme family
JG486_25395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JG486_25405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JG486_25420	COG2323	membrane
JG486_25425	COG5566	PFAM Mor transcription activator
JG486_25435	COG0733	neurotransmitter:sodium symporter activity
JG486_25440	COG2244	polysaccharide biosynthetic process
JG486_25450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JG486_25455	COG2223	nitrite transmembrane transporter activity
JG486_25460	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JG486_25475	COG0477	Major facilitator Superfamily
JG486_25480	COG0640	Transcriptional regulator
JG486_25485	COG2814	Major facilitator Superfamily
JG486_25495	COG1695	Transcriptional regulator
JG486_25520	COG2814	Major facilitator Superfamily
JG486_25530	COG0860	N-Acetylmuramoyl-L-alanine amidase
JG486_25595	COG1846	Transcriptional regulator
JG486_25600	COG0784	Response regulator, receiver
JG486_25605	COG4191	Histidine kinase
JG486_25610	COG0281	malic enzyme
JG486_25615	COG1027	Aspartate ammonia-lyase
JG486_25625	COG0528	UMP kinase activity
JG486_25650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JG486_25670	COG1131	(ABC) transporter
JG486_25705	COG2733	membrane
JG486_25725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JG486_25730	COG0785	Cytochrome C biogenesis protein
JG486_25750	COG3340	Belongs to the peptidase S51 family
JG486_25755	COG0534	Mate efflux family protein
JG486_25775	COG0277	FAD linked oxidase domain protein
JG486_25785	COG1757	Na H antiporter
JG486_25790	COG0438	transferase activity, transferring glycosyl groups
JG486_25790	COG1216	Glycosyl transferase, family 2
JG486_25805	COG0697	spore germination
JG486_25810	COG1802	Transcriptional regulator
JG486_25840	COG0367	asparagine synthase
JG486_25920	COG3842	ATPase activity
JG486_25925	COG0583	DNA-binding transcription factor activity
JG486_25935	COG2814	Major facilitator Superfamily
JG486_25950	COG2329	Antibiotic biosynthesis monooxygenase
JG486_25955	COG0412	Dienelactone hydrolase
JG486_25985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JG486_25990	COG4786	Flagellar basal body rod
JG486_25995	COG1419	protein localization to endoplasmic reticulum
JG486_26000	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JG486_26015	COG1987	bacterial-type flagellum assembly
JG486_26020	COG1338	Plays a role in the flagellum-specific transport system
JG486_26030	COG1776	CheC inhibitor of MCP methylation
JG486_26030	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JG486_26035	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JG486_26050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JG486_26060	COG0489	protein tyrosine kinase activity
JG486_26075	COG0314	molybdopterin synthase activity
JG486_26080	COG0303	'Molybdopterin
JG486_26085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JG486_26090	COG2116	formate transmembrane transporter activity
JG486_26100	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JG486_26105	COG5609	conserved protein (DUF2294)
JG486_26110	COG2427	Protein of unknown function (DUF1641)
JG486_26115	COG3383	formate dehydrogenase (NAD+) activity
JG486_26125	COG0861	Integral membrane protein TerC family
JG486_26145	COG0835	chemotaxis
JG486_26145	COG0784	Response regulator, receiver
JG486_26160	COG1749	Flagellar hook protein flgE
JG486_26190	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JG486_26195	COG1766	The M ring may be actively involved in energy transduction
JG486_26205	COG1558	bacterial-type flagellum-dependent cell motility
JG486_26210	COG1815	bacterial-type flagellum-dependent cell motility
JG486_26230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JG486_26255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JG486_26270	COG1776	CheC inhibitor of MCP methylation
JG486_26270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JG486_26280	COG2201	protein-glutamate methylesterase activity
JG486_26285	COG1360	Flagellar Motor Protein
JG486_26300	COG1923	regulation of RNA biosynthetic process
JG486_26320	COG2814	Major facilitator Superfamily
JG486_26360	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JG486_26365	COG2323	membrane
JG486_26375	COG0789	Transcriptional regulator
JG486_26375	COG4978	Transcriptional regulator
JG486_26380	COG0475	glutathione-regulated potassium exporter activity
JG486_26390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JG486_26415	COG1280	lysine exporter protein (LysE YggA)
JG486_26420	COG3403	YqcI/YcgG family
JG486_26455	COG0328	RNA-DNA hybrid ribonuclease activity
JG486_26475	COG0454	-acetyltransferase
JG486_26490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JG486_26530	COG2897	thiosulfate sulfurtransferase activity
JG486_26540	COG0456	acetyltransferase
JG486_26560	COG2311	Membrane
JG486_26565	COG2233	PERMEase
JG486_26575	COG0024	Methionine aminopeptidase
JG486_26590	COG1199	ATP-dependent helicase activity
JG486_26600	COG0116	Belongs to the methyltransferase superfamily
JG486_26610	COG3599	regulation of cell shape
JG486_26650	COG3331	DNA recombination
JG486_26655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JG486_26655	COG4499	WXG100 protein secretion system (Wss), protein YukC
JG486_26665	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JG486_26670	COG3935	DnaD domain protein
JG486_26690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JG486_26690	COG1199	ATP-dependent helicase activity
JG486_26700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JG486_26715	COG0617	tRNA 3'-terminal CCA addition
JG486_26720	COG0438	transferase activity, transferring glycosyl groups
JG486_26735	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JG486_26740	COG1694	Mazg nucleotide pyrophosphohydrolase
JG486_26745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JG486_26755	COG2738	Putative neutral zinc metallopeptidase
JG486_26770	COG4347	Protein of unknown function (DUF1405)
JG486_26785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JG486_26800	COG5582	Belongs to the UPF0302 family
JG486_26805	COG0457	Tetratricopeptide repeat
JG486_26810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JG486_26820	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JG486_26835	COG0142	geranyltranstransferase activity
JG486_26840	COG2226	methyltransferase
JG486_26845	COG0142	geranyltranstransferase activity
JG486_26850	COG0302	gtp cyclohydrolase
JG486_26860	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JG486_26880	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JG486_26885	COG1160	GTP binding
JG486_26915	COG1304	FMN binding
JG486_26935	COG0252	asparaginase activity
JG486_26940	COG0492	ferredoxin-NADP+ reductase activity
JG486_26960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JG486_26975	COG1408	metallophosphoesterase
JG486_26985	COG1266	CAAX protease self-immunity
JG486_26990	COG0514	ATP-dependent DNA helicase (RecQ)
JG486_27000	COG1141	Ferredoxin
JG486_27005	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JG486_27020	COG4942	peptidase
JG486_27025	COG2096	Adenosyltransferase
JG486_27030	COG5002	protein histidine kinase activity
JG486_27035	COG0745	RESPONSE REGULATOR receiver
JG486_27040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JG486_27045	COG1333	cytochrome c biogenesis protein
JG486_27055	COG1187	pseudouridine synthase activity
JG486_27060	COG0700	Nucleoside recognition
JG486_27070	COG1686	Belongs to the peptidase S11 family
JG486_27075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JG486_27110	COG0582	viral genome integration into host DNA
JG486_27120	COG1801	Protein of unknown function DUF72
JG486_27125	COG3852	Histidine kinase
JG486_27140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JG486_27145	COG1392	Phosphate transport regulator
JG486_27150	COG0306	phosphate transporter
JG486_27155	COG0730	response to heat
JG486_27275	COG0673	inositol 2-dehydrogenase activity
JG486_27280	COG0673	inositol 2-dehydrogenase activity
JG486_27285	COG2169	Transcriptional regulator
JG486_27310	COG1476	TRANSCRIPTIONal
JG486_27490	COG0463	Glycosyl transferase, family 2
JG486_27500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JG486_27505	COG1086	Polysaccharide biosynthesis protein
JG486_27510	COG1088	dTDP-glucose 4,6-dehydratase activity
JG486_27515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JG486_27520	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JG486_27535	COG2089	acid synthase
JG486_27540	COG4641	Protein conserved in bacteria
JG486_27610	COG1136	(ABC) transporter
JG486_27615	COG0577	efflux transmembrane transporter activity
JG486_27625	COG0582	viral genome integration into host DNA
JG486_27635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JG486_27705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JG486_27795	COG0024	Methionine aminopeptidase
JG486_27805	COG2002	toxin-antitoxin pair type II binding
JG486_27815	COG1923	regulation of RNA biosynthetic process
JG486_27885	COG2814	Major facilitator Superfamily
JG486_27910	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JG486_27925	COG2002	toxin-antitoxin pair type II binding
JG486_27965	COG0582	viral genome integration into host DNA
JG486_28005	COG2031	fatty acid transporter
JG486_28025	COG2312	Erythromycin esterase
JG486_28055	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JG486_28105	COG1396	sequence-specific DNA binding
JG486_28130	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JG486_28165	COG0745	RESPONSE REGULATOR receiver
JG486_28200	COG0833	amino acid
JG486_28205	COG1285	pathogenesis
JG486_28210	COG2267	carboxylic ester hydrolase activity
JG486_28245	COG1136	(ABC) transporter
JG486_28270	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JG486_28275	COG0772	Belongs to the SEDS family
JG486_28280	COG2239	Acts as a magnesium transporter
JG486_28290	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JG486_28300	COG4974	Belongs to the 'phage' integrase family
JG486_28350	COG1329	Transcriptional regulator
JG486_28390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JG486_28405	COG2155	Conserved Protein
JG486_28440	COG4176	ABC-type proline glycine betaine transport system permease component
JG486_28445	COG4175	Glycine betaine
JG486_28445	COG0517	IMP dehydrogenase activity
JG486_28540	COG2357	RelA SpoT domain protein
JG486_28545	COG2814	Major facilitator Superfamily
JG486_28560	COG0745	RESPONSE REGULATOR receiver
JG486_28590	COG2040	homocysteine
JG486_28595	COG0833	amino acid
JG486_28610	COG1942	4-Oxalocrotonate Tautomerase
JG486_28615	COG0583	DNA-binding transcription factor activity
JG486_28625	COG1846	Transcriptional regulator
JG486_28635	COG1136	(ABC) transporter
JG486_28640	COG0577	efflux transmembrane transporter activity
JG486_28650	COG0741	lytic transglycosylase activity
JG486_28685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JG486_28695	COG1819	glycosyl
JG486_28700	COG0457	Tetratricopeptide repeat
JG486_28745	COG1819	glycosyl
JG486_28750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JG486_28755	COG2357	RelA SpoT domain protein
JG486_28760	COG1309	transcriptional regulator
JG486_28780	COG2814	Major facilitator Superfamily
JG486_28790	COG2002	toxin-antitoxin pair type II binding
JG486_28805	COG0582	viral genome integration into host DNA
JG486_28855	COG2140	Oxalate decarboxylase
JG486_28865	COG0024	Methionine aminopeptidase
JG486_28870	COG0384	phenazine biosynthesis protein PhzF
JG486_28995	COG1073	alpha beta
JG486_29000	COG0456	acetyltransferase
JG486_29010	COG0457	Tetratricopeptide repeat
JG486_29020	COG3718	enzyme involved in inositol metabolism
JG486_29025	COG0191	fructose-bisphosphate aldolase activity
JG486_29050	COG0673	inositol 2-dehydrogenase activity
JG486_29055	COG2814	Major facilitator Superfamily
JG486_29150	COG3391	amine dehydrogenase activity
JG486_29165	COG1396	sequence-specific DNA binding
JG486_29270	COG0457	Tetratricopeptide repeat
JG486_29290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JG486_29330	COG0367	asparagine synthase
JG486_29380	COG5632	N-Acetylmuramoyl-L-alanine amidase
JG486_29400	COG0739	heme binding
JG486_29410	COG0741	lytic transglycosylase activity
JG486_29495	COG0542	response to heat
JG486_29620	COG1404	Belongs to the peptidase S8 family
JG486_29645	COG2234	aminopeptidase activity
JG486_29655	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JG486_29670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JG486_29675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JG486_29680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JG486_29690	COG0456	acetyltransferase
JG486_29775	COG0592	DNA-directed DNA polymerase activity
JG486_29905	COG1518	maintenance of DNA repeat elements
JG486_29910	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JG486_30025	COG2755	lipolytic protein G-D-S-L family
JG486_30025	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JG486_30030	COG1476	TRANSCRIPTIONal
JG486_30055	COG2124	cytochrome p450
JG486_30070	COG0686	Belongs to the AlaDH PNT family
JG486_30165	COG0457	Tetratricopeptide repeat
JG486_30215	COG1074	ATP-dependent DNA helicase activity
JG486_30220	COG4974	Belongs to the 'phage' integrase family
JG486_30250	COG1956	GAF domain-containing protein
JG486_30305	COG4974	Belongs to the 'phage' integrase family
JG486_30325	COG4166	transmembrane transport
JG486_30395	COG0840	transmembrane signaling receptor activity
JG486_30415	COG0789	Transcriptional regulator
JG486_30425	COG2318	DinB family
JG486_30430	COG2378	regulation of single-species biofilm formation
JG486_30475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JG486_30565	COG1388	LysM domain
JG486_30570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JG486_30610	COG1278	Cold shock
JG486_30615	COG1476	TRANSCRIPTIONal
JG486_30775	COG4962	Type ii secretion system protein e
JG486_30850	COG1192	Involved in chromosome partitioning
JG486_30875	COG2732	(Barnase) inhibitor
JG486_30890	COG1674	ftsk spoiiie
JG486_30970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JG486_30980	COG0833	amino acid
JG486_31000	COG0697	spore germination
JG486_31045	COG3173	Aminoglycoside phosphotransferase