locus-tag	class	description
EXW44_00050	COG2205	protein histidine kinase activity
EXW44_00055	COG0745	RESPONSE REGULATOR receiver
EXW44_00080	COG0697	spore germination
EXW44_00110	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW44_00115	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW44_00120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW44_00125	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW44_00130	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW44_00135	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW44_00140	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW44_00145	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW44_00150	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW44_00155	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW44_00160	COG0138	bifunctional purine biosynthesis protein purh
EXW44_00165	COG0151	Belongs to the GarS family
EXW44_00185	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW44_00190	COG0210	DNA helicase
EXW44_00195	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW44_00200	COG4851	CamS sex pheromone cAM373 precursor
EXW44_00210	COG1012	belongs to the aldehyde dehydrogenase family
EXW44_00215	COG1335	isochorismatase
EXW44_00225	COG2011	ABC-type metal ion transport system permease component
EXW44_00230	COG1464	Belongs to the NlpA lipoprotein family
EXW44_00245	COG0003	Pfam Anion-transporting ATPase
EXW44_00250	COG1846	Transcriptional regulator
EXW44_00255	COG4682	membrane
EXW44_00265	COG0154	amidase activity
EXW44_00270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW44_00275	COG1597	lipid kinase activity
EXW44_00280	COG0546	phosphoglycolate phosphatase activity
EXW44_00285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW44_00295	COG1012	belongs to the aldehyde dehydrogenase family
EXW44_00300	COG2076	Multidrug Resistance protein
EXW44_00305	COG2309	aminopeptidase activity
EXW44_00320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW44_00330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW44_00335	COG5002	protein histidine kinase activity
EXW44_00340	COG4807	Protein conserved in bacteria
EXW44_00365	COG1757	Na H antiporter
EXW44_00370	COG1473	amidohydrolase
EXW44_00385	COG0450	alkyl hydroperoxide reductase
EXW44_00395	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW44_00405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW44_00410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW44_00415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW44_00425	COG0492	ferredoxin-NADP+ reductase activity
EXW44_00440	COG0166	Belongs to the GPI family
EXW44_00465	COG5002	protein histidine kinase activity
EXW44_00485	COG3541	Predicted nucleotidyltransferase
EXW44_00495	COG2814	Major facilitator Superfamily
EXW44_00500	COG0723	plastoquinol--plastocyanin reductase activity
EXW44_00500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW44_00510	COG0765	amino acid transport
EXW44_00515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW44_00525	COG3290	protein histidine kinase activity
EXW44_00525	COG0840	transmembrane signaling receptor activity
EXW44_00550	COG0549	Belongs to the carbamate kinase family
EXW44_00565	COG0277	FAD linked oxidase domain protein
EXW44_00570	COG0366	Alpha amylase catalytic
EXW44_00575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW44_00575	COG1263	PTS System
EXW44_00575	COG2190	(PTS) system
EXW44_00595	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW44_00600	COG0352	thiamine-phosphate diphosphorylase activity
EXW44_00605	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW44_00620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW44_00625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW44_00630	COG1116	anion transmembrane transporter activity
EXW44_00635	COG0488	(ABC) transporter
EXW44_00680	COG2270	Major facilitator Superfamily
EXW44_00710	COG2310	stress, protein
EXW44_00715	COG2310	stress, protein
EXW44_00720	COG2310	stress, protein
EXW44_00725	COG0861	Integral membrane protein TerC family
EXW44_00735	COG3853	Toxic anion resistance protein (TelA)
EXW44_00745	COG4840	Belongs to the UPF0435 family
EXW44_00750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW44_00760	COG1295	ribonuclease BN
EXW44_00765	COG2217	Heavy metal translocating P-type atpase
EXW44_00770	COG0697	spore germination
EXW44_00795	COG0586	Pfam SNARE associated Golgi protein
EXW44_00810	COG3871	stress protein (general stress protein 26)
EXW44_00815	COG0387	Pfam Sodium calcium exchanger
EXW44_00825	COG0535	radical SAM domain protein
EXW44_00845	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW44_00865	COG3829	transcription factor binding
EXW44_00875	COG0833	amino acid
EXW44_00880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW44_00900	COG2066	Belongs to the glutaminase family
EXW44_00910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW44_00910	COG1263	PTS System
EXW44_00915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW44_00930	COG1216	Glycosyl transferase, family 2
EXW44_00940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW44_00940	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW44_00945	COG0463	Glycosyl transferase, family 2
EXW44_00960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW44_00965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW44_00980	COG1228	amidohydrolase
EXW44_00985	COG1090	epimerase
EXW44_00990	COG2137	regulation of response to DNA damage stimulus
EXW44_01015	COG1988	membrane-bound metal-dependent
EXW44_01020	COG1194	a g-specific adenine glycosylase
EXW44_01035	COG3557	Belongs to the UPF0374 family
EXW44_01040	COG1132	(ABC) transporter
EXW44_01045	COG4129	membrane
EXW44_01055	COG0067	glutamate synthase
EXW44_01055	COG0070	glutamate synthase
EXW44_01055	COG0069	glutamate synthase activity
EXW44_01060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW44_01065	COG4555	ABC transporter
EXW44_01085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW44_01090	COG0735	belongs to the Fur family
EXW44_01210	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW44_01215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW44_01235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW44_01245	COG2766	serine protein kinase
EXW44_01250	COG2718	Belongs to the UPF0229 family
EXW44_01265	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW44_01270	COG2268	Band 7 protein
EXW44_01280	COG3290	protein histidine kinase activity
EXW44_01285	COG4565	transcriptional regulatory protein
EXW44_01290	COG2851	Citrate transporter
EXW44_01315	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW44_01320	COG3842	ATPase activity
EXW44_01325	COG1175	transmembrane transport
EXW44_01330	COG0395	ABC-type sugar transport system, permease component
EXW44_01340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW44_01345	COG0745	RESPONSE REGULATOR receiver
EXW44_01350	COG5002	protein histidine kinase activity
EXW44_01360	COG4990	cell redox homeostasis
EXW44_01370	COG3290	protein histidine kinase activity
EXW44_01375	COG4565	transcriptional regulatory protein
EXW44_01380	COG3493	citrate carrier protein
EXW44_01385	COG0281	malic enzyme
EXW44_01395	COG0697	spore germination
EXW44_01400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW44_01410	COG5002	protein histidine kinase activity
EXW44_01415	COG0745	RESPONSE REGULATOR receiver
EXW44_01420	COG0456	acetyltransferase
EXW44_01425	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW44_01430	COG3383	formate dehydrogenase (NAD+) activity
EXW44_01435	COG2427	Protein of unknown function (DUF1641)
EXW44_01450	COG0531	amino acid
EXW44_01460	COG0640	Transcriptional regulator
EXW44_01465	COG2217	Heavy metal translocating P-type atpase
EXW44_01470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW44_01480	COG3227	Zinc metalloprotease (Elastase)
EXW44_01500	COG2720	vancomycin resistance protein
EXW44_01505	COG1316	TRANSCRIPTIONal
EXW44_01510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW44_01515	COG0346	lactoylglutathione lyase activity
EXW44_01520	COG1253	flavin adenine dinucleotide binding
EXW44_01525	COG1027	Aspartate ammonia-lyase
EXW44_01530	COG1620	l-lactate permease
EXW44_01535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW44_01555	COG3104	oligopeptide transport
EXW44_01560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW44_01565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW44_01570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW44_01585	COG0156	8-amino-7-oxononanoate synthase activity
EXW44_01590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW44_01600	COG4548	von Willebrand factor, type A
EXW44_01605	COG0714	Associated with various cellular activities
EXW44_01625	COG0531	amino acid
EXW44_01630	COG2188	Transcriptional regulator
EXW44_01635	COG1263	PTS System
EXW44_01635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW44_01640	COG0366	Alpha amylase catalytic
EXW44_01655	COG0697	spore germination
EXW44_01660	COG4585	Histidine kinase
EXW44_01665	COG2197	response regulator
EXW44_01670	COG1404	Belongs to the peptidase S8 family
EXW44_01685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW44_01690	COG1115	amino acid carrier protein
EXW44_01695	COG1126	abc transporter atp-binding protein
EXW44_01700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW44_01705	COG0765	amino acid transport
EXW44_01710	COG0765	amino acid transport
EXW44_01715	COG0833	amino acid
EXW44_01740	COG2378	regulation of single-species biofilm formation
EXW44_01745	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW44_01750	COG5002	protein histidine kinase activity
EXW44_01755	COG0745	RESPONSE REGULATOR receiver
EXW44_01765	COG0659	secondary active sulfate transmembrane transporter activity
EXW44_01780	COG2271	Major facilitator Superfamily
EXW44_01785	COG1846	Transcriptional regulator
EXW44_01790	COG0477	Major facilitator Superfamily
EXW44_01795	COG1609	Transcriptional regulator
EXW44_01800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW44_01805	COG1869	D-ribose catabolic process
EXW44_01815	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW44_01820	COG1879	ABC-type sugar transport system periplasmic component
EXW44_01850	COG1063	alcohol dehydrogenase
EXW44_01865	COG3568	Endonuclease Exonuclease Phosphatase
EXW44_01895	COG0840	transmembrane signaling receptor activity
EXW44_01900	COG3584	3D domain protein
EXW44_01900	COG1388	LysM domain
EXW44_01905	COG1476	TRANSCRIPTIONal
EXW44_01925	COG3104	oligopeptide transport
EXW44_01930	COG1114	Component of the transport system for branched-chain amino acids
EXW44_01945	COG1113	amino acid transport
EXW44_01950	COG2252	PERMEase
EXW44_01965	COG2153	protein acetylation
EXW44_01975	COG0475	glutathione-regulated potassium exporter activity
EXW44_01975	COG0569	domain protein
EXW44_01990	COG1845	cytochrome c oxidase, subunit III
EXW44_01995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW44_02005	COG0833	amino acid
EXW44_02010	COG4990	cell redox homeostasis
EXW44_02025	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW44_02030	COG0697	spore germination
EXW44_02035	COG0531	amino acid
EXW44_02045	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW44_02050	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW44_02060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW44_02065	COG0573	inorganic phosphate transmembrane transporter activity
EXW44_02070	COG0581	inorganic phosphate transmembrane transporter activity
EXW44_02080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW44_02200	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW44_02215	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW44_02215	COG4991	sh3 domain protein
EXW44_02215	COG3103	Sh3 type 3 domain protein
EXW44_02220	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW44_02225	COG1116	anion transmembrane transporter activity
EXW44_02230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW44_02235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW44_02240	COG0352	thiamine-phosphate diphosphorylase activity
EXW44_02245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW44_02250	COG2104	thiamine diphosphate biosynthetic process
EXW44_02255	COG2022	thiamine diphosphate biosynthetic process
EXW44_02260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW44_02265	COG0351	phosphomethylpyrimidine kinase
EXW44_02290	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW44_02295	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW44_02300	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW44_02305	COG2205	protein histidine kinase activity
EXW44_02310	COG2814	Major facilitator Superfamily
EXW44_02315	COG1846	Transcriptional regulator
EXW44_02335	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW44_02340	COG1129	ABC transporter
EXW44_02345	COG1879	ABC-type sugar transport system periplasmic component
EXW44_02350	COG2252	PERMEase
EXW44_02355	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_02370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW44_02375	COG1621	beta-fructofuranosidase activity
EXW44_02380	COG1263	PTS System
EXW44_02380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW44_02385	COG1609	Transcriptional regulator
EXW44_02435	COG0778	Nitroreductase
EXW44_02440	COG2719	SpoVR family
EXW44_02465	COG1937	Protein conserved in bacteria
EXW44_02470	COG0425	Belongs to the sulfur carrier protein TusA family
EXW44_02470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW44_02475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW44_02475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW44_02480	COG0425	Belongs to the sulfur carrier protein TusA family
EXW44_02485	COG0425	Belongs to the sulfur carrier protein TusA family
EXW44_02485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW44_02490	COG2210	Belongs to the sulfur carrier protein TusA family
EXW44_02495	COG0730	response to heat
EXW44_02505	COG1316	TRANSCRIPTIONal
EXW44_02510	COG0604	alcohol dehydrogenase
EXW44_02515	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW44_02525	COG0604	alcohol dehydrogenase
EXW44_02530	COG2814	Major facilitator Superfamily
EXW44_02545	COG3711	transcriptional antiterminator
EXW44_02545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW44_02550	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW44_02555	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW44_02580	COG1388	LysM domain
EXW44_02580	COG3584	3D domain protein
EXW44_02585	COG0577	efflux transmembrane transporter activity
EXW44_02590	COG1136	(ABC) transporter
EXW44_02600	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW44_02615	COG1114	Component of the transport system for branched-chain amino acids
EXW44_02620	COG3546	catalase activity
EXW44_02650	COG0586	Pfam SNARE associated Golgi protein
EXW44_02685	COG0531	amino acid
EXW44_02690	COG0475	glutathione-regulated potassium exporter activity
EXW44_02700	COG1737	Transcriptional regulator
EXW44_02705	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW44_02710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW44_02710	COG1263	PTS System
EXW44_02720	COG2259	Doxx family
EXW44_02740	COG0697	spore germination
EXW44_02745	COG1522	sequence-specific DNA binding
EXW44_02755	COG0300	oxidoreductase activity
EXW44_02770	COG2076	Multidrug Resistance protein
EXW44_02775	COG1309	transcriptional regulator
EXW44_02780	COG2814	Major facilitator Superfamily
EXW44_02785	COG1733	regulation of RNA biosynthetic process
EXW44_02795	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW44_02805	COG4533	DNA binding
EXW44_02810	COG2211	Major facilitator Superfamily
EXW44_02825	COG0531	amino acid
EXW44_02830	COG1012	belongs to the aldehyde dehydrogenase family
EXW44_02845	COG1132	(ABC) transporter
EXW44_02850	COG1132	(ABC) transporter
EXW44_02855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW44_02860	COG0765	amino acid transport
EXW44_02865	COG1126	abc transporter atp-binding protein
EXW44_02880	COG0189	ligase activity
EXW44_02890	COG4399	Belongs to the UPF0754 family
EXW44_02895	COG3679	Belongs to the UPF0342 family
EXW44_02910	COG0028	Belongs to the TPP enzyme family
EXW44_02915	COG3527	Alpha-acetolactate decarboxylase
EXW44_02920	COG0463	Glycosyl transferase, family 2
EXW44_02925	COG1216	Glycosyl transferase, family 2
EXW44_02930	COG2094	Belongs to the DNA glycosylase MPG family
EXW44_02935	COG0561	phosphatase activity
EXW44_02945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW44_02950	COG0318	PFAM AMP-dependent synthetase and ligase
EXW44_02960	COG0659	secondary active sulfate transmembrane transporter activity
EXW44_02975	COG0653	protein targeting
EXW44_02980	COG2244	polysaccharide biosynthetic process
EXW44_02990	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW44_03010	COG1696	Membrane protein involved in D-alanine export
EXW44_03025	COG1024	Enoyl-CoA hydratase
EXW44_03040	COG1363	Peptidase, m42
EXW44_03055	COG2318	DinB family
EXW44_03075	COG0579	oxidoreductase
EXW44_03110	COG0601	transmembrane transport
EXW44_03115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW44_03120	COG0444	Belongs to the ABC transporter superfamily
EXW44_03125	COG4608	Belongs to the ABC transporter superfamily
EXW44_03230	COG0582	viral genome integration into host DNA
EXW44_03335	COG0477	Major facilitator Superfamily
EXW44_03340	COG3290	protein histidine kinase activity
EXW44_03345	COG4565	transcriptional regulatory protein
EXW44_03350	COG3181	Tripartite tricarboxylate transporter family receptor
EXW44_03355	COG0494	nUDIX hydrolase
EXW44_03360	COG0513	Belongs to the DEAD box helicase family
EXW44_03385	COG0326	Molecular chaperone. Has ATPase activity
EXW44_03420	COG1475	DNA binding
EXW44_03430	COG0305	Participates in initiation and elongation during chromosome replication
EXW44_03460	COG0477	Major facilitator Superfamily
EXW44_03550	COG2814	Major facilitator Superfamily
EXW44_03555	COG0640	Transcriptional regulator
EXW44_03575	COG2376	Dihydroxyacetone kinase
EXW44_03590	COG2376	Dihydroxyacetone kinase
EXW44_03605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW44_03620	COG1335	isochorismatase
EXW44_03645	COG0076	glutamate decarboxylase activity
EXW44_03670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW44_03675	COG1278	Cold shock
EXW44_03685	COG3266	domain, Protein
EXW44_03685	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EXW44_03685	COG4932	domain protein
EXW44_03690	COG0737	Belongs to the 5'-nucleotidase family
EXW44_03690	COG1525	nuclease
EXW44_03690	COG4085	toxin activity
EXW44_03705	COG0582	viral genome integration into host DNA
EXW44_03720	COG2378	regulation of single-species biofilm formation
EXW44_03725	COG2318	DinB family
EXW44_03730	COG3266	domain, Protein
EXW44_03730	COG4932	domain protein
EXW44_03730	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EXW44_03740	COG0825	malonyl-CoA metabolic process
EXW44_03760	COG3237	CsbD-like
EXW44_03780	COG2172	sigma factor antagonist activity
EXW44_03785	COG1191	sigma factor activity
EXW44_03795	COG2208	phosphoserine phosphatase activity
EXW44_03800	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW44_03805	COG2205	protein histidine kinase activity
EXW44_03805	COG0784	Response regulator, receiver
EXW44_03805	COG5002	protein histidine kinase activity
EXW44_03845	COG2807	transmembrane transport
EXW44_03850	COG2186	Transcriptional regulator
EXW44_03855	COG4585	Histidine kinase
EXW44_03860	COG2197	response regulator
EXW44_03890	COG0420	3'-5' exonuclease activity
EXW44_03895	COG4717	serine-type aminopeptidase activity
EXW44_03900	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW44_03910	COG0346	lactoylglutathione lyase activity
EXW44_03915	COG0346	lactoylglutathione lyase activity
EXW44_03920	COG0457	Tetratricopeptide repeat
EXW44_03930	COG2267	carboxylic ester hydrolase activity
EXW44_03955	COG3620	sequence-specific DNA binding
EXW44_03960	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW44_03965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW44_03970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW44_03975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW44_03980	COG1595	DNA-templated transcription, initiation
EXW44_03995	COG3973	AAA domain
EXW44_04000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW44_04015	COG1846	Transcriptional regulator
EXW44_04025	COG0537	adenosine 5'-monophosphoramidase activity
EXW44_04030	COG1131	(ABC) transporter
EXW44_04035	COG4473	ABC transporter
EXW44_04050	COG2222	sugar isomerase
EXW44_04060	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW44_04065	COG3715	PTS system
EXW44_04070	COG3716	PTS system mannose fructose sorbose family IID component
EXW44_04075	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW44_04075	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW44_04090	COG3684	Belongs to the aldolase LacD family
EXW44_04095	COG2188	Transcriptional regulator
EXW44_04100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW44_04115	COG0247	lactate metabolic process
EXW44_04120	COG1139	Iron-sulfur cluster binding protein
EXW44_04125	COG1556	Lactate utilization protein
EXW44_04140	COG3402	PFAM membrane-flanked domain
EXW44_04145	COG3428	Bacterial PH domain
EXW44_04175	COG3402	PFAM membrane-flanked domain
EXW44_04180	COG3428	Bacterial PH domain
EXW44_04185	COG2329	Antibiotic biosynthesis monooxygenase
EXW44_04190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW44_04195	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW44_04200	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW44_04205	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW44_04230	COG1309	transcriptional regulator
EXW44_04235	COG1511	domain protein
EXW44_04270	COG2378	regulation of single-species biofilm formation
EXW44_04275	COG1609	Transcriptional regulator
EXW44_04285	COG1234	tRNA 3'-trailer cleavage
EXW44_04290	COG0095	Lipoate-protein ligase
EXW44_04300	COG0318	PFAM AMP-dependent synthetase and ligase
EXW44_04315	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW44_04320	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW44_04325	COG4208	sulfate ABC transporter
EXW44_04340	COG1408	metallophosphoesterase
EXW44_04345	COG1078	dGTPase activity
EXW44_04360	COG1595	DNA-templated transcription, initiation
EXW44_04370	COG3708	Transcriptional regulator
EXW44_04370	COG2207	Transcriptional regulator
EXW44_04375	COG2205	protein histidine kinase activity
EXW44_04380	COG0745	RESPONSE REGULATOR receiver
EXW44_04400	COG0501	Belongs to the peptidase M48B family
EXW44_04405	COG0697	spore germination
EXW44_04435	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW44_04440	COG2224	Isocitrate lyase
EXW44_04450	COG1278	Cold shock
EXW44_04465	COG4903	ComK protein
EXW44_04470	COG0398	Pfam SNARE associated Golgi protein
EXW44_04480	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW44_04485	COG1074	ATP-dependent DNA helicase activity
EXW44_04535	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW44_04560	COG0367	asparagine synthase
EXW44_04570	COG0753	catalase activity
EXW44_04575	COG0004	ammonium transporteR
EXW44_04585	COG1666	GTP binding
EXW44_04590	COG2996	Protein conserved in bacteria
EXW44_04595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW44_04605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW44_04620	COG0561	phosphatase activity
EXW44_04640	COG2267	carboxylic ester hydrolase activity
EXW44_04655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW44_04660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW44_04665	COG5504	Zn-dependent protease
EXW44_04675	COG0180	Tryptophanyl-tRNA synthetase
EXW44_04690	COG4166	transmembrane transport
EXW44_04695	COG0601	transmembrane transport
EXW44_04700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW44_04705	COG0444	Belongs to the ABC transporter superfamily
EXW44_04710	COG4608	Belongs to the ABC transporter superfamily
EXW44_04715	COG0534	Mate efflux family protein
EXW44_04720	COG4166	transmembrane transport
EXW44_04740	COG0861	Integral membrane protein TerC family
EXW44_04745	COG4862	establishment of competence for transformation
EXW44_04750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW44_04760	COG1164	Oligoendopeptidase f
EXW44_04770	COG2346	COG2346, Truncated hemoglobins
EXW44_04775	COG4116	CYTH
EXW44_04785	COG2357	RelA SpoT domain protein
EXW44_04795	COG0564	pseudouridine synthase activity
EXW44_04805	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW44_04810	COG0772	Belongs to the SEDS family
EXW44_04815	COG1216	Glycosyl transferase, family 2
EXW44_04835	COG0457	Tetratricopeptide repeat
EXW44_04835	COG0463	Glycosyl transferase, family 2
EXW44_04855	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW44_04870	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW44_04915	COG2153	protein acetylation
EXW44_04920	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW44_04925	COG2382	esterase
EXW44_04950	COG5492	domain, Protein
EXW44_04955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW44_04970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW44_04970	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW44_04975	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW44_04980	COG0134	indole-3-glycerol-phosphate synthase activity
EXW44_04985	COG0135	phosphoribosylanthranilate isomerase activity
EXW44_04990	COG0133	tryptophan synthase activity
EXW44_04995	COG0159	tryptophan synthase activity
EXW44_05005	COG1620	l-lactate permease
EXW44_05010	COG5634	Uncharacterized conserved protein (DUF2278)
EXW44_05045	COG2226	methyltransferase
EXW44_05065	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW44_05070	COG0567	Dehydrogenase, E1 component
EXW44_05075	COG1476	TRANSCRIPTIONal
EXW44_05135	COG1686	Belongs to the peptidase S11 family
EXW44_05140	COG0681	Belongs to the peptidase S26 family
EXW44_05175	COG1012	belongs to the aldehyde dehydrogenase family
EXW44_05185	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW44_05190	COG1177	transmembrane transport
EXW44_05195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW44_05205	COG2409	Drug exporters of the RND superfamily
EXW44_05215	COG0564	pseudouridine synthase activity
EXW44_05225	COG2340	Cysteine-rich secretory protein family
EXW44_05230	COG0247	lactate metabolic process
EXW44_05235	COG0277	FAD linked oxidase domain protein
EXW44_05240	COG3835	regulator
EXW44_05250	COG0745	RESPONSE REGULATOR receiver
EXW44_05255	COG5002	protein histidine kinase activity
EXW44_05260	COG2186	Transcriptional regulator
EXW44_05265	COG0247	lactate metabolic process
EXW44_05270	COG1139	Iron-sulfur cluster binding protein
EXW44_05275	COG1556	Lactate utilization protein
EXW44_05280	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW44_05290	COG2116	formate transmembrane transporter activity
EXW44_05295	COG0861	Integral membrane protein TerC family
EXW44_05300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW44_05310	COG2030	dehydratase
EXW44_05330	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_05335	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW44_05345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW44_05360	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW44_05365	COG3842	ATPase activity
EXW44_05375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW44_05380	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW44_05390	COG1349	DNA-binding transcription factor activity
EXW44_05400	COG0235	Class ii aldolase
EXW44_05410	COG2861	carbohydrate metabolic process
EXW44_05420	COG3852	Histidine kinase
EXW44_05425	COG1846	Transcriptional regulator
EXW44_05435	COG2318	DinB family
EXW44_05440	COG5002	protein histidine kinase activity
EXW44_05445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW44_05450	COG0720	synthase
EXW44_05460	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW44_05465	COG4873	Protein conserved in bacteria
EXW44_05475	COG0456	acetyltransferase
EXW44_05495	COG1780	Probably involved in ribonucleotide reductase function
EXW44_05510	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW44_05515	COG0531	amino acid
EXW44_05520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW44_05535	COG2204	response regulator
EXW44_05540	COG1012	belongs to the aldehyde dehydrogenase family
EXW44_05550	COG1725	Transcriptional regulator
EXW44_05555	COG1131	(ABC) transporter
EXW44_05565	COG1131	(ABC) transporter
EXW44_05570	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW44_05575	COG1266	CAAX protease self-immunity
EXW44_05585	COG1522	sequence-specific DNA binding
EXW44_05595	COG1335	isochorismatase
EXW44_05605	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW44_05610	COG2070	2-Nitropropane dioxygenase
EXW44_05615	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW44_05620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW44_05625	COG1696	Membrane protein involved in D-alanine export
EXW44_05645	COG0716	FMN binding
EXW44_05695	COG1846	Transcriptional regulator
EXW44_05705	COG1301	dicarboxylic acid transport
EXW44_05710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW44_05720	COG3874	Sporulation protein YtfJ
EXW44_05740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW44_05745	COG0028	Belongs to the TPP enzyme family
EXW44_05750	COG0440	acetolactate synthase activity
EXW44_05760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW44_05770	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW44_05780	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW44_05785	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW44_05795	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW44_05800	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW44_05805	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW44_05810	COG0107	imidazoleglycerol-phosphate synthase activity
EXW44_05820	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW44_05825	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW44_05840	COG1183	phosphatidylcholine synthase activity
EXW44_05845	COG1368	sulfuric ester hydrolase activity
EXW44_05855	COG0019	diaminopimelate decarboxylase activity
EXW44_05865	COG0175	sulfate reduction
EXW44_05870	COG2046	Belongs to the sulfate adenylyltransferase family
EXW44_05875	COG0529	Catalyzes the synthesis of activated sulfate
EXW44_05880	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW44_05900	COG1648	precorrin-2 dehydrogenase activity
EXW44_05910	COG0733	neurotransmitter:sodium symporter activity
EXW44_05930	COG1757	Na H antiporter
EXW44_05945	COG4758	membrane
EXW44_05950	COG4585	Histidine kinase
EXW44_05955	COG2197	response regulator
EXW44_05965	COG1114	Component of the transport system for branched-chain amino acids
EXW44_05975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW44_06020	COG0730	response to heat
EXW44_06025	COG0306	phosphate transporter
EXW44_06030	COG1392	Phosphate transport regulator
EXW44_06035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW44_06050	COG3852	Histidine kinase
EXW44_06055	COG1801	Protein of unknown function DUF72
EXW44_06065	COG0582	viral genome integration into host DNA
EXW44_06070	COG5002	protein histidine kinase activity
EXW44_06085	COG0392	lysyltransferase activity
EXW44_06085	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW44_06100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW44_06105	COG1686	Belongs to the peptidase S11 family
EXW44_06110	COG2715	membrane protein required for spore maturation
EXW44_06115	COG0700	Nucleoside recognition
EXW44_06120	COG1187	pseudouridine synthase activity
EXW44_06130	COG1333	cytochrome c biogenesis protein
EXW44_06135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW44_06140	COG0745	RESPONSE REGULATOR receiver
EXW44_06145	COG5002	protein histidine kinase activity
EXW44_06150	COG2096	Adenosyltransferase
EXW44_06155	COG4942	peptidase
EXW44_06165	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW44_06170	COG1141	Ferredoxin
EXW44_06180	COG4955	Helix-turn-helix domain
EXW44_06185	COG0514	ATP-dependent DNA helicase (RecQ)
EXW44_06190	COG1266	CAAX protease self-immunity
EXW44_06200	COG1408	metallophosphoesterase
EXW44_06215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW44_06235	COG0492	ferredoxin-NADP+ reductase activity
EXW44_06240	COG0252	asparaginase activity
EXW44_06245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW44_06255	COG1304	FMN binding
EXW44_06290	COG1160	GTP binding
EXW44_06295	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW44_06315	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW44_06325	COG0302	gtp cyclohydrolase
EXW44_06330	COG0142	geranyltranstransferase activity
EXW44_06335	COG2226	methyltransferase
EXW44_06340	COG0142	geranyltranstransferase activity
EXW44_06355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW44_06365	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW44_06370	COG0457	Tetratricopeptide repeat
EXW44_06375	COG5582	Belongs to the UPF0302 family
EXW44_06390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW44_06410	COG4347	Protein of unknown function (DUF1405)
EXW44_06425	COG2738	Putative neutral zinc metallopeptidase
EXW44_06435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW44_06440	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW44_06445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW44_06450	COG1803	Methylglyoxal synthase
EXW44_06455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW44_06460	COG0438	transferase activity, transferring glycosyl groups
EXW44_06465	COG0617	tRNA 3'-terminal CCA addition
EXW44_06475	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW44_06480	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW44_06490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW44_06490	COG1199	ATP-dependent helicase activity
EXW44_06510	COG3935	DnaD domain protein
EXW44_06515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW44_06525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW44_06525	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW44_06530	COG3331	DNA recombination
EXW44_06565	COG4474	Belongs to the UPF0398 family
EXW44_06570	COG3599	regulation of cell shape
EXW44_06580	COG0116	Belongs to the methyltransferase superfamily
EXW44_06590	COG1199	ATP-dependent helicase activity
EXW44_06595	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW44_06605	COG0024	Methionine aminopeptidase
EXW44_06615	COG2233	PERMEase
EXW44_06620	COG2311	Membrane
EXW44_06625	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW44_06635	COG0456	acetyltransferase
EXW44_06645	COG2897	thiosulfate sulfurtransferase activity
EXW44_06685	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW44_06700	COG0454	-acetyltransferase
EXW44_06720	COG0328	RNA-DNA hybrid ribonuclease activity
EXW44_06755	COG3403	YqcI/YcgG family
EXW44_06760	COG1280	lysine exporter protein (LysE YggA)
EXW44_06775	COG3162	membrane
EXW44_06780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW44_06785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW44_06795	COG0475	glutathione-regulated potassium exporter activity
EXW44_06800	COG4978	Transcriptional regulator
EXW44_06800	COG0789	Transcriptional regulator
EXW44_06810	COG2323	membrane
EXW44_06815	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW44_06845	COG2814	Major facilitator Superfamily
EXW44_06865	COG1923	regulation of RNA biosynthetic process
EXW44_06875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW44_06880	COG1360	Flagellar Motor Protein
EXW44_06885	COG2201	protein-glutamate methylesterase activity
EXW44_06890	COG2198	Histidine kinase
EXW44_06890	COG0643	Histidine kinase
EXW44_06895	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW44_06895	COG1776	CheC inhibitor of MCP methylation
EXW44_06910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW44_06930	COG1256	bacterial-type flagellum assembly
EXW44_06935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW44_06960	COG1815	bacterial-type flagellum-dependent cell motility
EXW44_06965	COG1558	bacterial-type flagellum-dependent cell motility
EXW44_06975	COG1766	The M ring may be actively involved in energy transduction
EXW44_06980	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW44_06990	COG1157	protein secretion by the type III secretion system
EXW44_07010	COG1749	Flagellar hook protein flgE
EXW44_07025	COG0784	Response regulator, receiver
EXW44_07025	COG0835	chemotaxis
EXW44_07045	COG0861	Integral membrane protein TerC family
EXW44_07055	COG3383	formate dehydrogenase (NAD+) activity
EXW44_07060	COG2427	Protein of unknown function (DUF1641)
EXW44_07065	COG5609	conserved protein (DUF2294)
EXW44_07070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW44_07080	COG2116	formate transmembrane transporter activity
EXW44_07085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW44_07090	COG0303	'Molybdopterin
EXW44_07095	COG0314	molybdopterin synthase activity
EXW44_07100	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW44_07110	COG0489	protein tyrosine kinase activity
EXW44_07115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW44_07120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW44_07125	COG0741	lytic transglycosylase activity
EXW44_07135	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW44_07140	COG1776	CheC inhibitor of MCP methylation
EXW44_07140	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW44_07150	COG1338	Plays a role in the flagellum-specific transport system
EXW44_07155	COG1987	bacterial-type flagellum assembly
EXW44_07165	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW44_07170	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW44_07175	COG1419	protein localization to endoplasmic reticulum
EXW44_07180	COG4786	Flagellar basal body rod
EXW44_07185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW44_07215	COG0412	Dienelactone hydrolase
EXW44_07220	COG2329	Antibiotic biosynthesis monooxygenase
EXW44_07235	COG2814	Major facilitator Superfamily
EXW44_07245	COG0583	DNA-binding transcription factor activity
EXW44_07250	COG3842	ATPase activity
EXW44_07300	COG0406	alpha-ribazole phosphatase activity
EXW44_07330	COG0367	asparagine synthase
EXW44_07360	COG1802	Transcriptional regulator
EXW44_07365	COG0697	spore germination
EXW44_07380	COG0438	transferase activity, transferring glycosyl groups
EXW44_07380	COG1216	Glycosyl transferase, family 2
EXW44_07385	COG1757	Na H antiporter
EXW44_07395	COG0277	FAD linked oxidase domain protein
EXW44_07415	COG0534	Mate efflux family protein
EXW44_07420	COG3340	Belongs to the peptidase S51 family
EXW44_07440	COG0785	Cytochrome C biogenesis protein
EXW44_07445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW44_07460	COG3048	D-serine ammonia-lyase activity
EXW44_07465	COG2733	membrane
EXW44_07505	COG1131	(ABC) transporter
EXW44_07520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW44_07555	COG0528	UMP kinase activity
EXW44_07565	COG1027	Aspartate ammonia-lyase
EXW44_07570	COG0281	malic enzyme
EXW44_07575	COG4191	Histidine kinase
EXW44_07580	COG0784	Response regulator, receiver
EXW44_07585	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW44_07600	COG2502	aspartate--ammonia ligase
EXW44_07640	COG1051	belongs to the nudix hydrolase family
EXW44_07645	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW44_07655	COG2814	Major facilitator Superfamily
EXW44_07685	COG0477	Major facilitator Superfamily
EXW44_07690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW44_07700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW44_07705	COG2223	nitrite transmembrane transporter activity
EXW44_07710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW44_07725	COG2244	polysaccharide biosynthetic process
EXW44_07730	COG0733	neurotransmitter:sodium symporter activity
EXW44_07740	COG5566	PFAM Mor transcription activator
EXW44_07745	COG2323	membrane
EXW44_07760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW44_07770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW44_07775	COG0028	Belongs to the TPP enzyme family
EXW44_07790	COG0129	dihydroxy-acid dehydratase activity
EXW44_07795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW44_07820	COG2814	Major facilitator Superfamily
EXW44_07825	COG3384	dioxygenase
EXW44_07850	COG4166	transmembrane transport
EXW44_07885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW44_07905	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW44_07910	COG1054	Belongs to the UPF0176 family
EXW44_07920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW44_07925	COG0531	amino acid
EXW44_07960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW44_07975	COG4257	antibiotic catabolic process
EXW44_07980	COG2390	Transcriptional regulator
EXW44_07990	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW44_07995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW44_08000	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW44_08015	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW44_08030	COG0583	DNA-binding transcription factor activity
EXW44_08050	COG0006	proline dipeptidase activity
EXW44_08055	COG2132	Multicopper oxidase
EXW44_08070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW44_08090	COG1114	Component of the transport system for branched-chain amino acids
EXW44_08100	COG4641	Protein conserved in bacteria
EXW44_08115	COG2372	response to copper ion
EXW44_08115	COG1276	copper resistance
EXW44_08120	COG4549	nuclear export factor GLE1
EXW44_08130	COG0697	spore germination
EXW44_08135	COG0583	DNA-binding transcription factor activity
EXW44_08140	COG1959	2 iron, 2 sulfur cluster binding
EXW44_08145	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW44_08150	COG0778	Nitroreductase
EXW44_08160	COG0628	permease
EXW44_08175	COG1231	oxidoreductase activity
EXW44_08180	COG0523	cobalamin synthesis protein
EXW44_08190	COG0318	PFAM AMP-dependent synthetase and ligase
EXW44_08195	COG2030	dehydratase
EXW44_08200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW44_08215	COG0411	ABC transporter
EXW44_08235	COG0583	DNA-binding transcription factor activity
EXW44_08245	COG1942	4-Oxalocrotonate Tautomerase
EXW44_08260	COG0346	lactoylglutathione lyase activity
EXW44_08270	COG1271	oxidase subunit
EXW44_08275	COG1294	oxidase, subunit
EXW44_08280	COG4988	ABC transporter
EXW44_08285	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW44_08315	COG1686	Belongs to the peptidase S11 family
EXW44_08330	COG1388	LysM domain
EXW44_08330	COG0791	NLP P60 protein
EXW44_08340	COG1132	(ABC) transporter
EXW44_08345	COG0745	RESPONSE REGULATOR receiver
EXW44_08350	COG5002	protein histidine kinase activity
EXW44_08355	COG0300	oxidoreductase activity
EXW44_08360	COG4122	O-methyltransferase activity
EXW44_08390	COG0460	homoserine dehydrogenase
EXW44_08400	COG0083	homoserine kinase activity
EXW44_08415	COG1316	TRANSCRIPTIONal
EXW44_08440	COG1285	pathogenesis
EXW44_08445	COG1247	-acetyltransferase
EXW44_08465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW44_08475	COG1082	Xylose isomerase domain protein TIM barrel
EXW44_08485	COG2814	Major facilitator Superfamily
EXW44_08490	COG1279	arginine transmembrane transporter activity
EXW44_08495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW44_08505	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW44_08535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW44_08540	COG0577	efflux transmembrane transporter activity
EXW44_08545	COG2002	toxin-antitoxin pair type II binding
EXW44_08550	COG1404	Belongs to the peptidase S8 family
EXW44_08560	COG3842	ATPase activity
EXW44_08565	COG2508	Transcriptional regulator
EXW44_08575	COG1653	transport
EXW44_08580	COG1175	transmembrane transport
EXW44_08585	COG0395	ABC-type sugar transport system, permease component
EXW44_08590	COG5426	von Willebrand factor, type A
EXW44_08595	COG1940	carbohydrate kinase activity
EXW44_08600	COG2222	sugar isomerase
EXW44_08610	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW44_08615	COG3684	Belongs to the aldolase LacD family
EXW44_08620	COG0366	Alpha amylase catalytic
EXW44_08625	COG0366	Alpha amylase catalytic
EXW44_08630	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW44_08635	COG0640	Transcriptional regulator
EXW44_08640	COG0667	Aldo Keto reductase
EXW44_08685	COG3949	Membrane
EXW44_08690	COG0783	Belongs to the Dps family
EXW44_08705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW44_08715	COG1231	oxidoreductase activity
EXW44_08720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW44_08725	COG4989	oxidoreductase activity
EXW44_08730	COG0523	cobalamin synthesis protein
EXW44_08735	COG0456	acetyltransferase
EXW44_08740	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW44_08755	COG1902	pentaerythritol trinitrate reductase activity
EXW44_08760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW44_08770	COG4166	transmembrane transport
EXW44_08775	COG0346	lactoylglutathione lyase activity
EXW44_08785	COG0406	alpha-ribazole phosphatase activity
EXW44_08795	COG5337	Spore coat protein CotH
EXW44_08800	COG1051	belongs to the nudix hydrolase family
EXW44_08805	COG0586	Pfam SNARE associated Golgi protein
EXW44_08810	COG2244	polysaccharide biosynthetic process
EXW44_08820	COG0701	Predicted permease
EXW44_08825	COG3689	TIGRFAM TIGR03943 family protein
EXW44_08830	COG1607	acyl-coa hydrolase
EXW44_08840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW44_08860	COG0702	epimerase
EXW44_08865	COG2839	Protein conserved in bacteria
EXW44_08870	COG1253	flavin adenine dinucleotide binding
EXW44_08885	COG1114	Component of the transport system for branched-chain amino acids
EXW44_08890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW44_08910	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW44_08925	COG1876	peptidase activity
EXW44_08940	COG2211	Major facilitator Superfamily
EXW44_08955	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW44_08965	COG0561	phosphatase activity
EXW44_08975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW44_08995	COG1819	glycosyl
EXW44_09000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW44_09005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW44_09030	COG0456	acetyltransferase
EXW44_09065	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW44_09155	COG3874	Sporulation protein YtfJ
EXW44_09180	COG2226	methyltransferase
EXW44_09200	COG1082	Xylose isomerase domain protein TIM barrel
EXW44_09205	COG0346	lactoylglutathione lyase activity
EXW44_09215	COG0604	alcohol dehydrogenase
EXW44_09220	COG1595	DNA-templated transcription, initiation
EXW44_09245	COG0426	domain, Protein
EXW44_09245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW44_09255	COG0386	Belongs to the glutathione peroxidase family
EXW44_09260	COG1305	Transglutaminase-like
EXW44_09265	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW44_09270	COG0714	Associated with various cellular activities
EXW44_09275	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW44_09305	COG2359	stage V sporulation protein S
EXW44_09315	COG2856	Zn peptidase
EXW44_09345	COG1396	sequence-specific DNA binding
EXW44_09395	COG3344	reverse transcriptase
EXW44_09425	COG0582	viral genome integration into host DNA
EXW44_09430	COG2267	carboxylic ester hydrolase activity
EXW44_09450	COG0582	viral genome integration into host DNA
EXW44_09465	COG5484	DNA packaging
EXW44_09470	COG1783	phage Terminase large subunit
EXW44_09485	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EXW44_09490	COG4653	Phage capsid family
EXW44_09620	COG1418	mRNA catabolic process
EXW44_09625	COG0488	(ABC) transporter
EXW44_09645	COG1413	lyase activity
EXW44_09660	COG2521	methyltransferase
EXW44_09660	COG2136	Putative SAM-dependent methyltransferase
EXW44_09665	COG0018	arginyl-trna synthetase
EXW44_09725	COG0017	Asparaginyl-tRNA synthetase
EXW44_09730	COG0733	neurotransmitter:sodium symporter activity
EXW44_09755	COG2610	gluconate transmembrane transporter activity
EXW44_09765	COG1794	racemase activity, acting on amino acids and derivatives
EXW44_09775	COG0456	acetyltransferase
EXW44_09780	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW44_09790	COG1131	(ABC) transporter
EXW44_09795	COG4473	ABC transporter
EXW44_09805	COG0546	phosphoglycolate phosphatase activity
EXW44_09820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW44_09835	COG0768	penicillin binding
EXW44_09845	COG0204	Acyl-transferase
EXW44_09850	COG1272	protein, Hemolysin III
EXW44_09855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW44_09860	COG0805	protein transport
EXW44_09875	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW44_09880	COG1999	signal sequence binding
EXW44_09885	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW44_09890	COG0367	asparagine synthase
EXW44_09905	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW44_09910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW44_09915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW44_09935	COG1335	isochorismatase
EXW44_09945	COG0668	transmembrane transport
EXW44_09950	COG2203	Gaf domain
EXW44_09950	COG4585	Histidine kinase
EXW44_09955	COG2197	response regulator
EXW44_09960	COG1737	Transcriptional regulator
EXW44_09965	COG1064	alcohol dehydrogenase
EXW44_09980	COG1070	Carbohydrate kinase
EXW44_09990	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW44_10010	COG1125	glycine betaine transport
EXW44_10010	COG0517	IMP dehydrogenase activity
EXW44_10015	COG1174	glycine betaine transport
EXW44_10050	COG1253	flavin adenine dinucleotide binding
EXW44_10055	COG1012	belongs to the aldehyde dehydrogenase family
EXW44_10060	COG5506	Protein of unknown function (DUF1694)
EXW44_10075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW44_10080	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW44_10085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW44_10090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW44_10095	COG0456	acetyltransferase
EXW44_10100	COG3829	transcription factor binding
EXW44_10105	COG1509	lysine 2,3-aminomutase activity
EXW44_10115	COG4479	Belongs to the UPF0346 family
EXW44_10140	COG0515	serine threonine protein kinase
EXW44_10140	COG3064	Membrane
EXW44_10140	COG4991	sh3 domain protein
EXW44_10150	COG0671	phosphoesterase, PA-phosphatase related
EXW44_10155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW44_10160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW44_10215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW44_10245	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_10265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW44_10265	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW44_10285	COG0372	Belongs to the citrate synthase family
EXW44_10290	COG2079	MmgE PrpD family protein
EXW44_10295	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW44_10300	COG1960	acyl-CoA dehydrogenase activity
EXW44_10305	COG2084	Dehydrogenase
EXW44_10310	COG1012	belongs to the aldehyde dehydrogenase family
EXW44_10315	COG1280	lysine exporter protein (LysE YggA)
EXW44_10320	COG1024	Enoyl-CoA hydratase
EXW44_10335	COG0420	3'-5' exonuclease activity
EXW44_10355	COG2223	nitrite transmembrane transporter activity
EXW44_10360	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_10365	COG1169	isochorismate synthase
EXW44_10370	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW44_10375	COG1535	isochorismatase
EXW44_10375	COG3433	isochorismatase activity
EXW44_10380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW44_10385	COG3251	PFAM MbtH domain protein
EXW44_10390	COG2814	Major facilitator Superfamily
EXW44_10405	COG0776	regulation of translation
EXW44_10415	COG2318	DinB family
EXW44_10420	COG1115	amino acid carrier protein
EXW44_10435	COG2329	Antibiotic biosynthesis monooxygenase
EXW44_10450	COG1187	pseudouridine synthase activity
EXW44_10455	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW44_10460	COG3655	Transcriptional regulator
EXW44_10470	COG1136	(ABC) transporter
EXW44_10480	COG0596	Alpha beta hydrolase
EXW44_10495	COG0028	Belongs to the TPP enzyme family
EXW44_10520	COG1253	flavin adenine dinucleotide binding
EXW44_10550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW44_10570	COG1846	Transcriptional regulator
EXW44_10580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW44_10585	COG1309	transcriptional regulator
EXW44_10615	COG1247	-acetyltransferase
EXW44_10655	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW44_10665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW44_10695	COG0583	DNA-binding transcription factor activity
EXW44_10700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW44_10715	COG0583	DNA-binding transcription factor activity
EXW44_10720	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW44_10725	COG2258	MOSC domain
EXW44_10740	COG1132	(ABC) transporter
EXW44_10745	COG1132	(ABC) transporter
EXW44_10760	COG0189	ligase activity
EXW44_10770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW44_10780	COG4974	Belongs to the 'phage' integrase family
EXW44_10805	COG1396	sequence-specific DNA binding
EXW44_10840	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW44_10845	COG1595	DNA-templated transcription, initiation
EXW44_10925	COG2755	lipolytic protein G-D-S-L family
EXW44_10925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW44_10935	COG2169	Transcriptional regulator
EXW44_10945	COG0673	inositol 2-dehydrogenase activity
EXW44_10985	COG1649	PFAM Uncharacterised BCR, COG1649
EXW44_11005	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW44_11010	COG2971	BadF BadG BcrA BcrD
EXW44_11020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW44_11070	COG1309	transcriptional regulator
EXW44_11085	COG1136	(ABC) transporter
EXW44_11085	COG0577	efflux transmembrane transporter activity
EXW44_11090	COG0500	methyltransferase
EXW44_11090	COG3615	Tellurite resistance protein tehB
EXW44_11100	COG0693	protein deglycase activity
EXW44_11110	COG0588	phosphoglycerate mutase activity
EXW44_11130	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW44_11135	COG0110	maltose O-acetyltransferase activity
EXW44_11150	COG1136	(ABC) transporter
EXW44_11180	COG1136	(ABC) transporter
EXW44_11185	COG0577	efflux transmembrane transporter activity
EXW44_11210	COG1686	Belongs to the peptidase S11 family
EXW44_11235	COG0768	penicillin binding
EXW44_11240	COG0745	RESPONSE REGULATOR receiver
EXW44_11245	COG2205	protein histidine kinase activity
EXW44_11250	COG1136	(ABC) transporter
EXW44_11255	COG0577	efflux transmembrane transporter activity
EXW44_11265	COG1595	DNA-templated transcription, initiation
EXW44_11275	COG0768	penicillin binding
EXW44_11280	COG0768	penicillin binding
EXW44_11315	COG1252	NADH dehydrogenase
EXW44_11320	COG0425	Belongs to the sulfur carrier protein TusA family
EXW44_11320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW44_11335	COG0697	spore germination
EXW44_11360	COG3397	chitin binding
EXW44_11365	COG0823	Involved in the tonB-independent uptake of proteins
EXW44_11375	COG1408	metallophosphoesterase
EXW44_11385	COG1131	(ABC) transporter
EXW44_11395	COG1309	transcriptional regulator
EXW44_11405	COG1960	acyl-CoA dehydrogenase activity
EXW44_11410	COG0439	Biotin carboxylase
EXW44_11415	COG0511	ligase activity, forming carbon-carbon bonds
EXW44_11420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW44_11425	COG1024	Enoyl-CoA hydratase
EXW44_11430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW44_11435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW44_11450	COG3344	reverse transcriptase
EXW44_11485	COG2318	DinB family
EXW44_11515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW44_11545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW44_11575	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_11580	COG1733	regulation of RNA biosynthetic process
EXW44_11605	COG1309	transcriptional regulator
EXW44_11635	COG0697	spore germination
EXW44_11640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW44_11675	COG2323	membrane
EXW44_11690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW44_11695	COG0697	spore germination
EXW44_11715	COG0201	protein transport
EXW44_11725	COG0737	Belongs to the 5'-nucleotidase family
EXW44_11730	COG3227	Zinc metalloprotease (Elastase)
EXW44_11735	COG1523	belongs to the glycosyl hydrolase 13 family
EXW44_11750	COG0076	glutamate decarboxylase activity
EXW44_11755	COG0657	acetylesterase activity
EXW44_11765	COG1073	alpha beta
EXW44_11775	COG0577	efflux transmembrane transporter activity
EXW44_11780	COG1136	(ABC) transporter
EXW44_11795	COG5002	protein histidine kinase activity
EXW44_11800	COG0745	RESPONSE REGULATOR receiver
EXW44_11830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW44_11835	COG1183	phosphatidylcholine synthase activity
EXW44_11850	COG1132	(ABC) transporter
EXW44_11860	COG3961	Belongs to the TPP enzyme family
EXW44_11880	COG0322	excinuclease ABC activity
EXW44_11905	COG2318	DinB family
EXW44_11920	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW44_11970	COG1051	belongs to the nudix hydrolase family
EXW44_11975	COG0592	DNA-directed DNA polymerase activity
EXW44_11980	COG2816	NAD+ diphosphatase activity
EXW44_11990	COG2223	nitrite transmembrane transporter activity
EXW44_11995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW44_12005	COG0494	nUDIX hydrolase
EXW44_12030	COG0697	spore germination
EXW44_12050	COG0584	glycerophosphoryl diester phosphodiesterase
EXW44_12065	COG2814	Major facilitator Superfamily
EXW44_12105	COG0768	penicillin binding
EXW44_12110	COG0671	phosphoesterase, PA-phosphatase related
EXW44_12115	COG0604	alcohol dehydrogenase
EXW44_12120	COG5002	protein histidine kinase activity
EXW44_12125	COG0745	RESPONSE REGULATOR receiver
EXW44_12135	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW44_12145	COG2205	protein histidine kinase activity
EXW44_12160	COG1122	ATPase activity
EXW44_12165	COG4720	Psort location CytoplasmicMembrane, score
EXW44_12170	COG1794	racemase activity, acting on amino acids and derivatives
EXW44_12175	COG1819	glycosyl
EXW44_12185	COG0768	penicillin binding
EXW44_12190	COG5002	protein histidine kinase activity
EXW44_12195	COG0561	phosphatase activity
EXW44_12245	COG2124	cytochrome p450
EXW44_12290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW44_12300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW44_12305	COG0460	homoserine dehydrogenase
EXW44_12325	COG0577	efflux transmembrane transporter activity
EXW44_12330	COG1136	(ABC) transporter
EXW44_12340	COG0488	(ABC) transporter
EXW44_12345	COG0667	Aldo Keto reductase
EXW44_12350	COG0583	DNA-binding transcription factor activity
EXW44_12355	COG2205	protein histidine kinase activity
EXW44_12360	COG0745	RESPONSE REGULATOR receiver
EXW44_12375	COG3773	Cell wall hydrolase
EXW44_12380	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW44_12390	COG3386	PFAM SMP-30 Gluconolaconase
EXW44_12430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW44_12445	COG2959	enzyme of heme biosynthesis
EXW44_12475	COG3483	tryptophan 2,3-dioxygenase activity
EXW44_12480	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW44_12485	COG3844	kynureninase activity
EXW44_12490	COG1309	transcriptional regulator
EXW44_12505	COG3284	Transcriptional regulator
EXW44_12520	COG1349	DNA-binding transcription factor activity
EXW44_12540	COG1959	2 iron, 2 sulfur cluster binding
EXW44_12555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW44_12560	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW44_12565	COG0022	dehydrogenase e1 component
EXW44_12570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW44_12590	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_12595	COG0456	acetyltransferase
EXW44_12595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW44_12625	COG4176	ABC-type proline glycine betaine transport system permease component
EXW44_12630	COG4175	Glycine betaine
EXW44_12630	COG0517	IMP dehydrogenase activity
EXW44_12655	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW44_12660	COG2153	protein acetylation
EXW44_12665	COG3397	chitin binding
EXW44_12675	COG1819	glycosyl
EXW44_12690	COG2205	protein histidine kinase activity
EXW44_12695	COG2315	Protein conserved in bacteria
EXW44_12740	COG3973	AAA domain
EXW44_12750	COG2105	PFAM AIG2 family protein
EXW44_12755	COG0514	ATP-dependent DNA helicase (RecQ)
EXW44_12775	COG4637	Psort location Cytoplasmic, score
EXW44_12785	COG1227	inorganic diphosphatase activity
EXW44_12790	COG3397	chitin binding
EXW44_12795	COG2318	DinB family
EXW44_12815	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW44_12820	COG1115	amino acid carrier protein
EXW44_12825	COG1012	belongs to the aldehyde dehydrogenase family
EXW44_12830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW44_12840	COG3938	Belongs to the proline racemase family
EXW44_12845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW44_12885	COG0586	Pfam SNARE associated Golgi protein
EXW44_12900	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW44_12905	COG4166	transmembrane transport
EXW44_12915	COG4948	Mandelate Racemase Muconate Lactonizing
EXW44_12935	COG0667	Aldo Keto reductase
EXW44_12975	COG2936	dipeptidyl-peptidase activity
EXW44_12985	COG0745	RESPONSE REGULATOR receiver
EXW44_13015	COG1164	Oligoendopeptidase f
EXW44_13020	COG0531	amino acid
EXW44_13025	COG1522	sequence-specific DNA binding
EXW44_13040	COG1307	EDD domain protein, DegV family
EXW44_13070	COG1335	isochorismatase
EXW44_13085	COG2814	Major facilitator Superfamily
EXW44_13095	COG1664	Polymer-forming cytoskeletal
EXW44_13100	COG0789	Transcriptional regulator
EXW44_13105	COG4533	DNA binding
EXW44_13110	COG0477	Major facilitator Superfamily
EXW44_13110	COG2814	Major facilitator Superfamily
EXW44_13130	COG2261	transglycosylase associated protein
EXW44_13145	COG2226	methyltransferase
EXW44_13180	COG0436	Aminotransferase
EXW44_13185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW44_13210	COG1131	(ABC) transporter
EXW44_13215	COG2188	Transcriptional regulator
EXW44_13260	COG0628	permease
EXW44_13305	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW44_13315	COG0697	spore germination
EXW44_13320	COG2318	DinB family
EXW44_13370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW44_13380	COG2814	Major facilitator Superfamily
EXW44_13385	COG1368	sulfuric ester hydrolase activity
EXW44_13400	COG0488	(ABC) transporter
EXW44_13405	COG2409	Drug exporters of the RND superfamily
EXW44_13405	COG1033	growth of symbiont in host cell
EXW44_13415	COG1309	transcriptional regulator
EXW44_13435	COG0287	Prephenate dehydrogenase
EXW44_13450	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW44_13450	COG1605	Chorismate mutase
EXW44_13495	COG3584	3D domain protein
EXW44_13495	COG1388	LysM domain
EXW44_13505	COG0346	lactoylglutathione lyase activity
EXW44_13515	COG0431	NADPH-dependent FMN reductase
EXW44_13545	COG0579	oxidoreductase
EXW44_13550	COG1879	ABC-type sugar transport system periplasmic component
EXW44_13565	COG1129	ABC transporter
EXW44_13570	COG2390	Transcriptional regulator
EXW44_13590	COG2226	methyltransferase
EXW44_13610	COG2329	Antibiotic biosynthesis monooxygenase
EXW44_13635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW44_13640	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW44_13645	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW44_13650	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW44_13655	COG3239	Fatty acid desaturase
EXW44_13675	COG3842	ATPase activity
EXW44_13700	COG1175	transmembrane transport
EXW44_13705	COG1349	DNA-binding transcription factor activity
EXW44_13715	COG3655	Transcriptional regulator
EXW44_13730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW44_13735	COG0346	lactoylglutathione lyase activity
EXW44_13770	COG0714	Associated with various cellular activities
EXW44_13790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW44_13795	COG0753	catalase activity
EXW44_13805	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW44_13830	COG0714	Associated with various cellular activities
EXW44_13840	COG0778	Nitroreductase
EXW44_13845	COG1846	Transcriptional regulator
EXW44_13980	COG0740	serine-type endopeptidase activity
EXW44_13990	COG4626	Terminase
EXW44_13990	COG1802	Transcriptional regulator
EXW44_14025	COG0582	viral genome integration into host DNA
EXW44_14065	COG2002	toxin-antitoxin pair type II binding
EXW44_14075	COG1484	DNA-dependent DNA replication
EXW44_14095	COG1396	sequence-specific DNA binding
EXW44_14120	COG0582	viral genome integration into host DNA
EXW44_14130	COG4884	unkown
EXW44_14130	COG3831	ATPase activity
EXW44_14150	COG2207	Transcriptional regulator
EXW44_14155	COG0456	acetyltransferase
EXW44_14170	COG0697	spore germination
EXW44_14175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW44_14205	COG0814	amino acid
EXW44_14210	COG0697	spore germination
EXW44_14220	COG0642	Histidine kinase
EXW44_14225	COG0745	RESPONSE REGULATOR receiver
EXW44_14230	COG0596	Alpha beta hydrolase
EXW44_14240	COG0456	acetyltransferase
EXW44_14240	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW44_14265	COG0730	response to heat
EXW44_14275	COG0833	amino acid
EXW44_14285	COG4335	DNA alkylation repair
EXW44_14315	COG0681	Belongs to the peptidase S26 family
EXW44_14320	COG0768	penicillin binding
EXW44_14335	COG3104	oligopeptide transport
EXW44_14340	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW44_14355	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW44_14360	COG1984	allophanate hydrolase subunit 2
EXW44_14365	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW44_14370	COG1414	Transcriptional regulator
EXW44_14390	COG1960	acyl-CoA dehydrogenase activity
EXW44_14415	COG0640	Transcriptional regulator
EXW44_14425	COG3314	Sporulation integral membrane protein YlbJ
EXW44_14445	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW44_14450	COG0577	efflux transmembrane transporter activity
EXW44_14455	COG0577	efflux transmembrane transporter activity
EXW44_14460	COG1136	(ABC) transporter
EXW44_14495	COG0574	Belongs to the PEP-utilizing enzyme family
EXW44_14495	COG3848	Pyruvate phosphate dikinase
EXW44_14505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW44_14525	COG0697	spore germination
EXW44_14550	COG1288	antiporter activity
EXW44_14565	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_14565	COG3347	Dehydrogenase
EXW44_14575	COG1070	Carbohydrate kinase
EXW44_14580	COG0235	Class ii aldolase
EXW44_14590	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW44_14600	COG4154	Belongs to the RbsD FucU family
EXW44_14615	COG0798	PFAM Bile acid sodium symporter
EXW44_14620	COG0346	lactoylglutathione lyase activity
EXW44_14625	COG0640	Transcriptional regulator
EXW44_14640	COG1309	transcriptional regulator
EXW44_14650	COG1522	sequence-specific DNA binding
EXW44_14670	COG0346	lactoylglutathione lyase activity
EXW44_14700	COG0745	RESPONSE REGULATOR receiver
EXW44_14705	COG5002	protein histidine kinase activity
EXW44_14705	COG3850	Histidine kinase
EXW44_14740	COG1073	alpha beta
EXW44_14750	COG0814	amino acid
EXW44_14760	COG1760	l-serine dehydratase
EXW44_14770	COG5002	protein histidine kinase activity
EXW44_14775	COG0745	RESPONSE REGULATOR receiver
EXW44_14785	COG5002	protein histidine kinase activity
EXW44_14810	COG4977	sequence-specific DNA binding
EXW44_14850	COG2814	Major facilitator Superfamily
EXW44_14865	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW44_14875	COG2309	aminopeptidase activity
EXW44_14885	COG1690	Belongs to the RtcB family
EXW44_14910	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW44_14930	COG1136	(ABC) transporter
EXW44_14935	COG0577	efflux transmembrane transporter activity
EXW44_14955	COG3850	Histidine kinase
EXW44_14955	COG5002	protein histidine kinase activity
EXW44_14965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW44_14980	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW44_15000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW44_15045	COG2814	Major facilitator Superfamily
EXW44_15080	COG2849	repeat protein
EXW44_15085	COG5444	nuclease activity
EXW44_15100	COG5444	nuclease activity
EXW44_15215	COG0477	Major facilitator Superfamily
EXW44_15230	COG1846	Transcriptional regulator
EXW44_15235	COG2814	Major facilitator Superfamily
EXW44_15255	COG2211	Major facilitator Superfamily
EXW44_15285	COG0640	Transcriptional regulator
EXW44_15315	COG1329	Transcriptional regulator
EXW44_15370	COG5002	protein histidine kinase activity
EXW44_15385	COG1136	(ABC) transporter
EXW44_15400	COG1131	(ABC) transporter
EXW44_15510	COG4187	Peptidase family M20/M25/M40
EXW44_15525	COG2031	fatty acid transporter
EXW44_15535	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW44_15585	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW44_15590	COG1288	antiporter activity
EXW44_15595	COG2356	endonuclease I
EXW44_15600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW44_15605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW44_15635	COG1785	Belongs to the alkaline phosphatase family
EXW44_15640	COG0778	Nitroreductase
EXW44_15645	COG1733	regulation of RNA biosynthetic process
EXW44_15665	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_15675	COG1131	(ABC) transporter
EXW44_15705	COG1595	DNA-templated transcription, initiation
EXW44_15720	COG1011	Hydrolase
EXW44_15725	COG2365	Tyrosine phosphatase family
EXW44_15750	COG0346	lactoylglutathione lyase activity
EXW44_15755	COG1940	carbohydrate kinase activity
EXW44_15760	COG0738	Major facilitator superfamily
EXW44_15765	COG0110	maltose O-acetyltransferase activity
EXW44_15780	COG0628	permease
EXW44_15785	COG2261	transglycosylase associated protein
EXW44_15815	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW44_15825	COG1253	flavin adenine dinucleotide binding
EXW44_15830	COG0789	Transcriptional regulator
EXW44_15840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW44_15865	COG0697	spore germination
EXW44_15870	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW44_15875	COG3813	Protein conserved in bacteria
EXW44_15880	COG2706	6-phosphogluconolactonase activity
EXW44_15885	COG1070	Carbohydrate kinase
EXW44_15895	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW44_15900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW44_15915	COG0814	amino acid
EXW44_15935	COG1393	Belongs to the ArsC family
EXW44_15945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW44_15960	COG0494	nUDIX hydrolase
EXW44_15975	COG0384	phenazine biosynthesis protein PhzF
EXW44_15985	COG0318	PFAM AMP-dependent synthetase and ligase
EXW44_15990	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW44_15995	COG1733	regulation of RNA biosynthetic process
EXW44_16010	COG1191	sigma factor activity
EXW44_16025	COG1876	peptidase activity
EXW44_16065	COG0741	lytic transglycosylase activity
EXW44_16090	COG5002	protein histidine kinase activity
EXW44_16140	COG0814	amino acid
EXW44_16165	COG1151	hydroxylamine reductase activity
EXW44_16190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW44_16200	COG2072	flavoprotein involved in K transport
EXW44_16245	COG1695	Transcriptional regulator
EXW44_16250	COG0604	alcohol dehydrogenase
EXW44_16255	COG1113	amino acid transport
EXW44_16265	COG2814	Major facilitator Superfamily
EXW44_16275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW44_16280	COG1012	belongs to the aldehyde dehydrogenase family
EXW44_16290	COG0534	Mate efflux family protein
EXW44_16295	COG1012	belongs to the aldehyde dehydrogenase family
EXW44_16300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW44_16315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW44_16320	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW44_16340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW44_16345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW44_16350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW44_16355	COG3739	integral membrane protein
EXW44_16375	COG0583	DNA-binding transcription factor activity
EXW44_16400	COG1193	negative regulation of DNA recombination
EXW44_16420	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW44_16425	COG1164	Oligoendopeptidase f
EXW44_16450	COG3781	membrane
EXW44_16465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW44_16500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW44_16505	COG0640	Transcriptional regulator
EXW44_16510	COG0604	alcohol dehydrogenase
EXW44_16515	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW44_16520	COG0457	Tetratricopeptide repeat
EXW44_16535	COG2808	Putative FMN-binding domain
EXW44_16540	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW44_16550	COG0277	FAD linked oxidase domain protein
EXW44_16570	COG1285	pathogenesis
EXW44_16580	COG2514	catechol 2,3-dioxygenase activity
EXW44_16585	COG2720	vancomycin resistance protein
EXW44_16610	COG1278	Cold shock
EXW44_16620	COG0716	FMN binding
EXW44_16630	COG0494	nUDIX hydrolase
EXW44_16650	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_16660	COG0165	Argininosuccinate lyase
EXW44_16675	COG4145	pantothenate transmembrane transporter activity
EXW44_16685	COG1012	belongs to the aldehyde dehydrogenase family
EXW44_16690	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_16700	COG1657	PFAM Prenyltransferase squalene oxidase
EXW44_16705	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW44_16710	COG2962	Rard protein
EXW44_16715	COG3326	Membrane
EXW44_16720	COG0531	amino acid
EXW44_16755	COG2226	methyltransferase
EXW44_16760	COG4166	transmembrane transport
EXW44_16765	COG4166	transmembrane transport
EXW44_16770	COG4166	transmembrane transport
EXW44_16775	COG1316	TRANSCRIPTIONal
EXW44_16785	COG1595	DNA-templated transcription, initiation
EXW44_16795	COG1131	(ABC) transporter
EXW44_16815	COG0673	inositol 2-dehydrogenase activity
EXW44_16820	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW44_16825	COG0187	DNA topoisomerase II activity
EXW44_16830	COG1832	CoA-binding protein
EXW44_16835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW44_16840	COG0745	RESPONSE REGULATOR receiver
EXW44_16850	COG1328	CTP reductase activity
EXW44_16860	COG4841	protein insertion into membrane
EXW44_16865	COG0824	Thioesterase
EXW44_16890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW44_16910	COG1132	(ABC) transporter
EXW44_16915	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW44_16945	COG2211	Major facilitator Superfamily
EXW44_16955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW44_16970	COG0183	Belongs to the thiolase family
EXW44_16975	COG0318	PFAM AMP-dependent synthetase and ligase
EXW44_16980	COG1268	BioY protein
EXW44_16985	COG0318	PFAM AMP-dependent synthetase and ligase
EXW44_16990	COG1396	sequence-specific DNA binding
EXW44_17035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW44_17050	COG5002	protein histidine kinase activity
EXW44_17060	COG0400	carboxylic ester hydrolase activity
EXW44_17065	COG0346	lactoylglutathione lyase activity
EXW44_17070	COG0069	glutamate synthase activity
EXW44_17075	COG1902	pentaerythritol trinitrate reductase activity
EXW44_17085	COG1329	Transcriptional regulator
EXW44_17090	COG0010	Belongs to the arginase family
EXW44_17100	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW44_17105	COG2986	histidine ammonia-lyase
EXW44_17115	COG2226	methyltransferase
EXW44_17145	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW44_17150	COG0785	Cytochrome C biogenesis protein
EXW44_17165	COG1473	amidohydrolase
EXW44_17170	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW44_17175	COG1131	(ABC) transporter
EXW44_17185	COG0583	DNA-binding transcription factor activity
EXW44_17195	COG1346	cytolysis
EXW44_17210	COG0730	response to heat
EXW44_17220	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW44_17220	COG3409	Peptidoglycan-binding domain 1 protein
EXW44_17240	COG1132	(ABC) transporter
EXW44_17245	COG1132	(ABC) transporter
EXW44_17250	COG3763	UPF0154 protein
EXW44_17270	COG3639	organic phosphonate transmembrane transporter activity
EXW44_17280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW44_17285	COG0737	Belongs to the 5'-nucleotidase family
EXW44_17295	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW44_17300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW44_17315	COG1695	Transcriptional regulator
EXW44_17320	COG1132	(ABC) transporter
EXW44_17350	COG0367	asparagine synthase
EXW44_17355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW44_17365	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW44_17370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW44_17375	COG3420	alginic acid biosynthetic process
EXW44_17375	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW44_17400	COG0438	transferase activity, transferring glycosyl groups
EXW44_17410	COG0463	Glycosyl transferase, family 2
EXW44_17410	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW44_17415	COG0438	transferase activity, transferring glycosyl groups
EXW44_17420	COG0438	transferase activity, transferring glycosyl groups
EXW44_17425	COG1086	Polysaccharide biosynthesis protein
EXW44_17430	COG0489	protein tyrosine kinase activity
EXW44_17435	COG3944	biosynthesis protein
EXW44_17440	COG0174	glutamine synthetase
EXW44_17445	COG0789	Transcriptional regulator
EXW44_17450	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW44_17455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW44_17460	COG2860	membrane
EXW44_17465	COG0464	growth
EXW44_17485	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW44_17495	COG3584	3D domain protein
EXW44_17495	COG1388	LysM domain
EXW44_17500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW44_17500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW44_17500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW44_17505	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW44_17510	COG1349	DNA-binding transcription factor activity
EXW44_17515	COG1979	alcohol dehydrogenase
EXW44_17520	COG2322	membrane
EXW44_17530	COG1113	amino acid transport
EXW44_17545	COG1473	amidohydrolase
EXW44_17550	COG1408	metallophosphoesterase
EXW44_17555	COG2116	formate transmembrane transporter activity
EXW44_17570	COG2217	Heavy metal translocating P-type atpase
EXW44_17575	COG2608	mercury ion transmembrane transporter activity
EXW44_17580	COG1937	Protein conserved in bacteria
EXW44_17610	COG4566	intracellular signal transduction
EXW44_17620	COG2819	hydrolase of the alpha beta superfamily
EXW44_17625	COG1120	ATPase activity
EXW44_17630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW44_17635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW44_17640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW44_17645	COG0708	Exodeoxyribonuclease III
EXW44_17650	COG2169	Transcriptional regulator
EXW44_17655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW44_17660	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW44_17665	COG2706	6-phosphogluconolactonase activity
EXW44_17670	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW44_17675	COG2364	Membrane
EXW44_17685	COG0346	lactoylglutathione lyase activity
EXW44_17690	COG5001	Diguanylate cyclase
EXW44_17690	COG3300	MHYT domain
EXW44_17730	COG1346	cytolysis
EXW44_17740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW44_17745	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW44_17745	COG0596	Alpha beta hydrolase
EXW44_17750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW44_17765	COG2188	Transcriptional regulator
EXW44_17770	COG2723	6-phospho-beta-galactosidase activity
EXW44_17775	COG0823	Involved in the tonB-independent uptake of proteins
EXW44_17780	COG3773	Cell wall hydrolase
EXW44_17790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW44_17800	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW44_17805	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW44_17810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW44_17820	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW44_17825	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW44_17830	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW44_17835	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW44_17835	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW44_17845	COG2359	stage V sporulation protein S
EXW44_17850	COG1692	metallophosphoesterase
EXW44_17855	COG1418	mRNA catabolic process
EXW44_17860	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW44_17865	COG1546	Belongs to the CinA family
EXW44_17865	COG1058	Belongs to the CinA family
EXW44_17870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW44_17875	COG1426	Protein conserved in bacteria
EXW44_17890	COG0300	oxidoreductase activity
EXW44_17895	COG0612	Peptidase, M16
EXW44_17900	COG0612	Peptidase, M16
EXW44_17905	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW44_17910	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW44_17915	COG3845	ABC transporter
EXW44_17920	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW44_17925	COG2188	Transcriptional regulator
EXW44_17935	COG1674	ftsk spoiiie
EXW44_17945	COG0740	serine-type endopeptidase activity
EXW44_17950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW44_17960	COG0527	aspartate kinase activity
EXW44_17965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW44_17970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW44_17975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW44_17980	COG1873	PFAM PRC-barrel domain
EXW44_17985	COG0612	Peptidase, M16
EXW44_17990	COG0726	polysaccharide deacetylase
EXW44_17995	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW44_18005	COG0196	riboflavin kinase activity
EXW44_18015	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW44_18020	COG1550	Protein conserved in bacteria
EXW44_18025	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW44_18030	COG1358	cellular component organization or biogenesis
EXW44_18035	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW44_18040	COG0195	Participates in both transcription termination and antitermination
EXW44_18045	COG0779	Required for maturation of 30S ribosomal subunits
EXW44_18055	COG0442	prolyl-tRNA aminoacylation
EXW44_18060	COG0750	zinc metalloprotease
EXW44_18070	COG4589	Belongs to the CDS family
EXW44_18080	COG0233	cytoplasmic translational termination
EXW44_18085	COG0528	UMP kinase activity
EXW44_18090	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW44_18100	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW44_18105	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW44_18110	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW44_18115	COG4974	Belongs to the 'phage' integrase family
EXW44_18120	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW44_18125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW44_18130	COG0758	DNA mediated transformation
EXW44_18135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW44_18140	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW44_18145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW44_18160	COG0335	large ribosomal subunit rRNA binding
EXW44_18165	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW44_18170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW44_18175	COG1837	Belongs to the UPF0109 family
EXW44_18185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW44_18195	COG0552	protein localization to endoplasmic reticulum
EXW44_18200	COG1196	nuclear chromosome segregation
EXW44_18205	COG0571	ribonuclease III activity
EXW44_18210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW44_18215	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_18220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW44_18225	COG0416	fatty acid biosynthetic process
EXW44_18230	COG2050	protein possibly involved in aromatic compounds catabolism
EXW44_18230	COG1349	DNA-binding transcription factor activity
EXW44_18235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW44_18240	COG1461	Dihydroxyacetone kinase
EXW44_18245	COG1302	Protein conserved in bacteria
EXW44_18260	COG1564	THIamine pyrophosphokinase
EXW44_18265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW44_18275	COG2815	serine threonine protein kinase
EXW44_18275	COG0515	serine threonine protein kinase
EXW44_18280	COG0631	protein serine/threonine phosphatase activity
EXW44_18285	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW44_18290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW44_18290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW44_18295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW44_18300	COG0242	peptide deformylase activity
EXW44_18305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW44_18310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW44_18315	COG1758	RNA polymerase activity
EXW44_18330	COG1561	YicC-like family, N-terminal region
EXW44_18335	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW44_18345	COG0006	proline dipeptidase activity
EXW44_18365	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW44_18375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EXW44_18385	COG0167	dihydroorotate dehydrogenase activity
EXW44_18390	COG0543	2 iron, 2 sulfur cluster binding
EXW44_18395	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW44_18405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW44_18410	COG0540	Belongs to the ATCase OTCase family
EXW44_18420	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW44_18425	COG0564	pseudouridine synthase activity
EXW44_18430	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW44_18440	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW44_18445	COG3599	regulation of cell shape
EXW44_18450	COG2302	S4 RNA-binding domain
EXW44_18455	COG0762	integral membrane protein
EXW44_18460	COG1799	cell septum assembly
EXW44_18465	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW44_18475	COG1873	PFAM PRC-barrel domain
EXW44_18480	COG1191	sigma factor activity
EXW44_18485	COG1191	sigma factor activity
EXW44_18495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW44_18500	COG0849	cell division
EXW44_18505	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW44_18520	COG0772	Belongs to the SEDS family
EXW44_18525	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW44_18530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW44_18535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW44_18540	COG0768	penicillin binding
EXW44_18545	COG0768	penicillin binding
EXW44_18555	COG0275	rRNA processing
EXW44_18560	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW44_18565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW44_18570	COG0454	-acetyltransferase
EXW44_18580	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW44_18585	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW44_18590	COG1323	Belongs to the UPF0348 family
EXW44_18595	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW44_18600	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW44_18605	COG3314	Sporulation integral membrane protein YlbJ
EXW44_18615	COG0742	ribosomal rna small subunit methyltransferase
EXW44_18625	COG4471	UPF0298 protein
EXW44_18630	COG3679	Belongs to the UPF0342 family
EXW44_18635	COG0406	alpha-ribazole phosphatase activity
EXW44_18650	COG2340	Cysteine-rich secretory protein family
EXW44_18660	COG3336	cytochrome c oxidase
EXW44_18685	COG0109	protoheme IX farnesyltransferase activity
EXW44_18690	COG1612	heme a metabolic process
EXW44_18695	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW44_18705	COG0772	Belongs to the SEDS family
EXW44_18710	COG4838	Belongs to the UPF0358 family
EXW44_18715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW44_18720	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW44_18730	COG4896	Protein conserved in bacteria
EXW44_18745	COG1217	gtp-binding protein TYPA
EXW44_18755	COG0483	inositol monophosphate 1-phosphatase activity
EXW44_18765	COG4493	Belongs to the UPF0637 family
EXW44_18770	COG4476	Belongs to the UPF0223 family
EXW44_18775	COG1982	Orn Lys Arg decarboxylase major
EXW44_18820	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW44_18825	COG0022	dehydrogenase e1 component
EXW44_18830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW44_18845	COG0561	phosphatase activity
EXW44_18855	COG5503	Protein of unknown function (DUF1447)
EXW44_18860	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW44_18865	COG0569	domain protein
EXW44_18875	COG1473	amidohydrolase
EXW44_18880	COG2171	N-acyltransferase activity
EXW44_18885	COG0583	DNA-binding transcription factor activity
EXW44_18890	COG0517	IMP dehydrogenase activity
EXW44_18900	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW44_18910	COG4703	Protein of unknown function (DUF1797)
EXW44_18925	COG2200	EAL domain
EXW44_18930	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_18935	COG1408	metallophosphoesterase
EXW44_18980	COG2814	Major facilitator Superfamily
EXW44_18990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW44_19000	COG3209	COG3209 Rhs family protein
EXW44_19010	COG2205	protein histidine kinase activity
EXW44_19020	COG0436	Aminotransferase
EXW44_19025	COG1609	Transcriptional regulator
EXW44_19030	COG3833	ABC-type maltose transport systems, permease component
EXW44_19035	COG1175	transmembrane transport
EXW44_19040	COG2182	Extracellular solute-binding protein
EXW44_19050	COG0366	Alpha amylase catalytic
EXW44_19055	COG3842	ATPase activity
EXW44_19100	COG0183	Belongs to the thiolase family
EXW44_19135	COG1695	Transcriptional regulator
EXW44_19140	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_19150	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW44_19155	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW44_19160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW44_19165	COG0436	Aminotransferase
EXW44_19170	COG1850	ribulose-bisphosphate carboxylase activity
EXW44_19175	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW44_19180	COG0235	Class ii aldolase
EXW44_19185	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW44_19200	COG2084	Dehydrogenase
EXW44_19210	COG2199	diguanylate cyclase activity
EXW44_19215	COG0778	Nitroreductase
EXW44_19240	COG2190	(PTS) system
EXW44_19240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW44_19240	COG1263	PTS System
EXW44_19245	COG3711	transcriptional antiterminator
EXW44_19255	COG2188	Transcriptional regulator
EXW44_19260	COG0363	glucosamine-6-phosphate deaminase activity
EXW44_19265	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW44_19275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW44_19285	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW44_19295	COG1547	Domain of unknown function (DUF309)
EXW44_19305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW44_19310	COG4086	secreted protein
EXW44_19315	COG0561	phosphatase activity
EXW44_19320	COG0697	spore germination
EXW44_19335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW44_19375	COG1686	Belongs to the peptidase S11 family
EXW44_19380	COG1725	Transcriptional regulator
EXW44_19385	COG1131	(ABC) transporter
EXW44_19410	COG1846	Transcriptional regulator
EXW44_19425	COG0598	Magnesium transport protein CorA
EXW44_19440	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW44_19450	COG4974	Belongs to the 'phage' integrase family
EXW44_19460	COG0735	belongs to the Fur family
EXW44_19465	COG1300	Membrane
EXW44_19485	COG0667	Aldo Keto reductase
EXW44_19490	COG0656	L-ascorbic acid biosynthetic process
EXW44_19495	COG0456	acetyltransferase
EXW44_19495	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW44_19505	COG4085	toxin activity
EXW44_19505	COG1525	nuclease
EXW44_19505	COG0737	Belongs to the 5'-nucleotidase family
EXW44_19510	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW44_19520	COG0596	Alpha beta hydrolase
EXW44_19525	COG2056	Na+-H+ antiporter family
EXW44_19530	COG1609	Transcriptional regulator
EXW44_19535	COG0456	acetyltransferase
EXW44_19540	COG1073	alpha beta
EXW44_19555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW44_19555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW44_19560	COG0307	riboflavin synthase, alpha
EXW44_19565	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW44_19565	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW44_19580	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW44_19585	COG4106	trans-aconitate 2-methyltransferase activity
EXW44_19590	COG1073	alpha beta
EXW44_19590	COG2226	methyltransferase
EXW44_19595	COG0156	8-amino-7-oxononanoate synthase activity
EXW44_19605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW44_19615	COG1757	Na H antiporter
EXW44_19620	COG0737	Belongs to the 5'-nucleotidase family
EXW44_19630	COG1522	sequence-specific DNA binding
EXW44_19665	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW44_19675	COG0300	oxidoreductase activity
EXW44_19680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW44_19685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW44_19690	COG1760	l-serine dehydratase
EXW44_19695	COG1760	l-serine dehydratase
EXW44_19705	COG1234	tRNA 3'-trailer cleavage
EXW44_19730	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW44_19735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW44_19745	COG1376	ErfK ybiS ycfS ynhG family protein
EXW44_19750	COG4129	membrane
EXW44_19755	COG1126	abc transporter atp-binding protein
EXW44_19760	COG0765	amino acid transport
EXW44_19765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW44_19780	COG2816	NAD+ diphosphatase activity
EXW44_19785	COG2323	membrane
EXW44_19790	COG0772	Belongs to the SEDS family
EXW44_19800	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW44_19805	COG0022	dehydrogenase e1 component
EXW44_19810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW44_19815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW44_19820	COG3426	butyrate kinase activity
EXW44_19830	COG0280	phosphate acetyltransferase
EXW44_19840	COG3290	protein histidine kinase activity
EXW44_19840	COG3829	transcription factor binding
EXW44_19850	COG0584	glycerophosphoryl diester phosphodiesterase
EXW44_19855	COG3093	addiction module antidote protein HigA
EXW44_19865	COG0745	RESPONSE REGULATOR receiver
EXW44_19875	COG0750	zinc metalloprotease
EXW44_19880	COG0497	DNA recombination
EXW44_19885	COG1438	arginine binding
EXW44_19890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW44_19895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW44_19900	COG0142	geranyltranstransferase activity
EXW44_19905	COG1722	exodeoxyribonuclease VII activity
EXW44_19910	COG1570	exodeoxyribonuclease VII activity
EXW44_19915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW44_19920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW44_19925	COG1302	Protein conserved in bacteria
EXW44_19930	COG0439	Biotin carboxylase
EXW44_19935	COG0511	ligase activity, forming carbon-carbon bonds
EXW44_19980	COG3854	ATPases associated with a variety of cellular activities
EXW44_20000	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW44_20005	COG0006	proline dipeptidase activity
EXW44_20010	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW44_20020	COG3872	metal-dependent enzyme
EXW44_20030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW44_20065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW44_20075	COG1609	Transcriptional regulator
EXW44_20085	COG2076	Multidrug Resistance protein
EXW44_20090	COG2076	Multidrug Resistance protein
EXW44_20130	COG1725	Transcriptional regulator
EXW44_20145	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW44_20150	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW44_20155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW44_20160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW44_20190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW44_20215	COG4970	Tfp pilus assembly protein FimT
EXW44_20225	COG1459	type II secretion system
EXW44_20230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW44_20285	COG0646	methionine synthase
EXW44_20285	COG1410	methionine synthase
EXW44_20290	COG0646	methionine synthase
EXW44_20290	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW44_20295	COG0626	cystathionine gamma-synthase activity
EXW44_20300	COG0626	cystathionine gamma-synthase activity
EXW44_20320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW44_20330	COG1940	carbohydrate kinase activity
EXW44_20335	COG4483	Protein conserved in bacteria
EXW44_20340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW44_20345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW44_20350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW44_20355	COG0704	Plays a role in the regulation of phosphate uptake
EXW44_20365	COG0581	inorganic phosphate transmembrane transporter activity
EXW44_20370	COG0573	inorganic phosphate transmembrane transporter activity
EXW44_20375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW44_20380	COG0768	penicillin binding
EXW44_20385	COG0477	Major facilitator Superfamily
EXW44_20390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW44_20410	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW44_20415	COG0735	belongs to the Fur family
EXW44_20420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW44_20425	COG1121	(ABC) transporter
EXW44_20430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW44_20440	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW44_20455	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW44_20460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW44_20465	COG2384	SAM-dependent methyltransferase
EXW44_20470	COG2010	Cytochrome c
EXW44_20475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW44_20480	COG0358	DNA primase activity
EXW44_20490	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW44_20495	COG0517	IMP dehydrogenase activity
EXW44_20500	COG1381	Involved in DNA repair and RecF pathway recombination
EXW44_20510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW44_20515	COG0295	cytidine deaminase activity
EXW44_20520	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW44_20525	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW44_20530	COG1480	7TM receptor with intracellular HD hydrolase
EXW44_20535	COG1702	phosphate starvation-inducible protein PhoH
EXW44_20550	COG1610	YqeY-like protein
EXW44_20555	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW44_20560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW44_20565	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW44_20575	COG0484	heat shock protein binding
EXW44_20585	COG0443	Heat shock 70 kDa protein
EXW44_20595	COG1420	regulation of RNA biosynthetic process
EXW44_20600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW44_20605	COG1733	regulation of RNA biosynthetic process
EXW44_20610	COG0481	GTPase activity
EXW44_20620	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW44_20625	COG0268	Binds directly to 16S ribosomal RNA
EXW44_20630	COG1466	dna polymerase III delta subunit
EXW44_20640	COG0658	competence protein
EXW44_20640	COG2333	competence protein COMEC
EXW44_20645	COG2131	deaminase
EXW44_20650	COG1555	photosystem II stabilization
EXW44_20650	COG1596	polysaccharide export
EXW44_20655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW44_20660	COG2226	methyltransferase
EXW44_20665	COG0799	negative regulation of ribosome biogenesis
EXW44_20670	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW44_20675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW44_20680	COG1534	Rna-binding protein
EXW44_20685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW44_20690	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW44_20695	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW44_20705	COG0688	phosphatidylethanolamine metabolic process
EXW44_20715	COG1595	DNA-templated transcription, initiation
EXW44_20720	COG2357	RelA SpoT domain protein
EXW44_20730	COG1785	Belongs to the alkaline phosphatase family
EXW44_20740	COG2267	carboxylic ester hydrolase activity
EXW44_20775	COG1404	Belongs to the peptidase S8 family
EXW44_20780	COG3186	Phenylalanine-4-hydroxylase
EXW44_20785	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW44_20790	COG2514	catechol 2,3-dioxygenase activity
EXW44_20795	COG2259	Doxx family
EXW44_20835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW44_20845	COG1012	belongs to the aldehyde dehydrogenase family
EXW44_20845	COG1454	alcohol dehydrogenase
EXW44_20850	COG0626	cystathionine gamma-synthase activity
EXW44_20855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW44_20860	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW44_20865	COG2226	methyltransferase
EXW44_20880	COG0768	penicillin binding
EXW44_20885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW44_20890	COG0572	uridine kinase
EXW44_20895	COG0826	peptidase U32
EXW44_20900	COG0826	peptidase U32
EXW44_20905	COG4122	O-methyltransferase activity
EXW44_20910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW44_20920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW44_20925	COG4472	Bacterial protein of unknown function (DUF965)
EXW44_20930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW44_20940	COG0628	permease
EXW44_20960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW44_20970	COG0482	sulfurtransferase activity
EXW44_20975	COG1104	cysteine desulfurase activity
EXW44_20980	COG1959	2 iron, 2 sulfur cluster binding
EXW44_20985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW44_20995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW44_21000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW44_21010	COG1490	D-aminoacyl-tRNA deacylase activity
EXW44_21015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW44_21020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW44_21025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW44_21025	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW44_21030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW44_21035	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW44_21035	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW44_21045	COG2244	polysaccharide biosynthetic process
EXW44_21050	COG2323	membrane
EXW44_21060	COG1862	Preprotein translocase
EXW44_21065	COG0343	queuine tRNA-ribosyltransferase activity
EXW44_21070	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW44_21080	COG2255	four-way junction helicase activity
EXW44_21085	COG0632	four-way junction helicase activity
EXW44_21090	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW44_21115	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW44_21120	COG0157	Belongs to the NadC ModD family
EXW44_21125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW44_21130	COG1104	cysteine desulfurase activity
EXW44_21135	COG1827	regulation of RNA biosynthetic process
EXW44_21140	COG2258	MOSC domain
EXW44_21145	COG0077	Prephenate dehydratase
EXW44_21150	COG0577	efflux transmembrane transporter activity
EXW44_21155	COG0577	efflux transmembrane transporter activity
EXW44_21160	COG1136	(ABC) transporter
EXW44_21165	COG5002	protein histidine kinase activity
EXW44_21170	COG0745	RESPONSE REGULATOR receiver
EXW44_21175	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW44_21180	COG3290	protein histidine kinase activity
EXW44_21190	COG2868	ribosomal protein
EXW44_21200	COG1530	ribonuclease E activity
EXW44_21205	COG1994	Peptidase M50
EXW44_21210	COG0739	heme binding
EXW44_21215	COG2894	cell division
EXW44_21220	COG0850	regulation of cytokinetic process
EXW44_21235	COG1077	Cell shape determining protein MreB Mrl
EXW44_21240	COG2003	Belongs to the UPF0758 family
EXW44_21245	COG0424	maF-like protein
EXW44_21260	COG0285	dihydrofolate synthase activity
EXW44_21275	COG1388	LysM domain
EXW44_21280	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW44_21285	COG0113	porphobilinogen synthase activity
EXW44_21290	COG1587	Uroporphyrinogen-III synthase
EXW44_21295	COG0181	hydroxymethylbilane synthase activity
EXW44_21300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW44_21305	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW44_21310	COG1846	Transcriptional regulator
EXW44_21315	COG1764	response to oxidative stress
EXW44_21320	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW44_21330	COG1067	ATP-dependent peptidase activity
EXW44_21330	COG0470	DNA polymerase III
EXW44_21340	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW44_21370	COG0622	Phosphoesterase
EXW44_21380	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW44_21385	COG5401	PFAM Sporulation and spore germination
EXW44_21395	COG0477	Major facilitator Superfamily
EXW44_21400	COG2197	response regulator
EXW44_21405	COG2233	PERMEase
EXW44_21410	COG0402	S-adenosylhomocysteine deaminase activity
EXW44_21415	COG1983	PspC domain protein
EXW44_21420	COG1396	sequence-specific DNA binding
EXW44_21425	COG0697	spore germination
EXW44_21435	COG1959	2 iron, 2 sulfur cluster binding
EXW44_21440	COG1668	transmembrane transport
EXW44_21445	COG4152	abc transporter atp-binding protein
EXW44_21450	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW44_21455	COG1360	Flagellar Motor Protein
EXW44_21460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW44_21470	COG1876	peptidase activity
EXW44_21475	COG0824	Thioesterase
EXW44_21480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW44_21485	COG1053	succinate dehydrogenase
EXW44_21490	COG2009	succinate dehydrogenase
EXW44_21495	COG1719	4-vinyl reductase, 4VR
EXW44_21500	COG0322	excinuclease ABC activity
EXW44_21505	COG3118	belongs to the thioredoxin family
EXW44_21510	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW44_21515	COG2086	electron transfer activity
EXW44_21520	COG1024	Enoyl-CoA hydratase
EXW44_21525	COG1309	transcriptional regulator
EXW44_21530	COG0318	PFAM AMP-dependent synthetase and ligase
EXW44_21555	COG2318	DinB family
EXW44_21575	COG1131	(ABC) transporter
EXW44_21580	COG2205	protein histidine kinase activity
EXW44_21585	COG0745	RESPONSE REGULATOR receiver
EXW44_21590	COG4895	conserved protein (DUF2196)
EXW44_21595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW44_21605	COG4509	Sortase family
EXW44_21610	COG1120	ATPase activity
EXW44_21625	COG5386	Cell surface protein
EXW44_21635	COG5386	Cell surface protein
EXW44_21640	COG1114	Component of the transport system for branched-chain amino acids
EXW44_21650	COG1193	negative regulation of DNA recombination
EXW44_21655	COG1796	DNA polymerase
EXW44_21655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW44_21660	COG1286	toxin biosynthetic process
EXW44_21665	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW44_21670	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW44_21695	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW44_21700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW44_21710	COG1418	mRNA catabolic process
EXW44_21740	COG2814	Major facilitator Superfamily
EXW44_21745	COG1566	PFAM secretion protein HlyD family protein
EXW44_21750	COG1309	transcriptional regulator
EXW44_21755	COG1363	Peptidase, m42
EXW44_21765	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW44_21780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW44_21790	COG1484	DNA-dependent DNA replication
EXW44_21795	COG3611	Membrane attachment protein
EXW44_21800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW44_21805	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW44_21810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW44_21815	COG0237	dephospho-CoA kinase activity
EXW44_21820	COG1971	Probably functions as a manganese efflux pump
EXW44_21830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW44_21830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW44_21835	COG5002	protein histidine kinase activity
EXW44_21840	COG0745	RESPONSE REGULATOR receiver
EXW44_21855	COG0039	L-malate dehydrogenase activity
EXW44_21860	COG0538	isocitrate dehydrogenase activity
EXW44_21865	COG0372	Belongs to the citrate synthase family
EXW44_21880	COG0628	permease
EXW44_21885	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW44_21895	COG0205	6-phosphofructokinase activity
EXW44_21905	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW44_21910	COG1725	Transcriptional regulator
EXW44_21915	COG0281	malic enzyme
EXW44_21920	COG0587	DNA-directed DNA polymerase activity
EXW44_21935	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW44_21955	COG4109	DRTGG domain
EXW44_21965	COG0006	proline dipeptidase activity
EXW44_21995	COG0662	Cupin 2, conserved barrel domain protein
EXW44_22005	COG1476	TRANSCRIPTIONal
EXW44_22020	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_22025	COG0589	response to stress
EXW44_22055	COG0137	argininosuccinate synthase activity
EXW44_22070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW44_22090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW44_22095	COG0827	DNA restriction-modification system
EXW44_22100	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW44_22105	COG3874	Sporulation protein YtfJ
EXW44_22120	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW44_22130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW44_22145	COG1104	cysteine desulfurase activity
EXW44_22150	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW44_22165	COG1309	transcriptional regulator
EXW44_22170	COG1956	GAF domain-containing protein
EXW44_22175	COG0626	cystathionine gamma-synthase activity
EXW44_22180	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW44_22205	COG1595	DNA-templated transcription, initiation
EXW44_22215	COG0110	maltose O-acetyltransferase activity
EXW44_22220	COG0456	acetyltransferase
EXW44_22225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW44_22230	COG0454	-acetyltransferase
EXW44_22235	COG0517	IMP dehydrogenase activity
EXW44_22240	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW44_22255	COG0745	RESPONSE REGULATOR receiver
EXW44_22260	COG5002	protein histidine kinase activity
EXW44_22275	COG1970	mechanosensitive ion channel activity
EXW44_22295	COG1609	Transcriptional regulator
EXW44_22305	COG1605	Chorismate mutase
EXW44_22305	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW44_22310	COG4851	CamS sex pheromone cAM373 precursor
EXW44_22315	COG3118	belongs to the thioredoxin family
EXW44_22325	COG2309	aminopeptidase activity
EXW44_22355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW44_22365	COG1674	ftsk spoiiie
EXW44_22380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW44_22385	COG4848	Belongs to the UPF0354 family
EXW44_22390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW44_22395	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW44_22400	COG1363	Peptidase, m42
EXW44_22410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW44_22415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW44_22425	COG0510	thiamine kinase activity
EXW44_22430	COG1523	belongs to the glycosyl hydrolase 13 family
EXW44_22440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW44_22445	COG1349	DNA-binding transcription factor activity
EXW44_22450	COG1187	pseudouridine synthase activity
EXW44_22455	COG2244	polysaccharide biosynthetic process
EXW44_22460	COG2081	HI0933 family
EXW44_22465	COG2814	Major facilitator Superfamily
EXW44_22475	COG3832	glyoxalase III activity
EXW44_22495	COG1329	Transcriptional regulator
EXW44_22520	COG0314	molybdopterin synthase activity
EXW44_22525	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW44_22530	COG0303	'Molybdopterin
EXW44_22535	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW44_22540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW44_22545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW44_22570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW44_22580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW44_22620	COG0495	leucyl-tRNA aminoacylation
EXW44_22625	COG2814	Major facilitator Superfamily
EXW44_22630	COG0475	glutathione-regulated potassium exporter activity
EXW44_22635	COG0490	domain, Protein
EXW44_22640	COG0582	viral genome integration into host DNA
EXW44_22655	COG1136	(ABC) transporter
EXW44_22670	COG1242	4 iron, 4 sulfur cluster binding
EXW44_22675	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW44_22685	COG1131	(ABC) transporter
EXW44_22695	COG1794	racemase activity, acting on amino acids and derivatives
EXW44_22715	COG2267	carboxylic ester hydrolase activity
EXW44_22720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW44_22725	COG0671	phosphoesterase, PA-phosphatase related
EXW44_22730	COG0438	transferase activity, transferring glycosyl groups
EXW44_22740	COG0521	Mo-molybdopterin cofactor biosynthetic process
EXW44_22760	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW44_22765	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW44_22805	COG5002	protein histidine kinase activity
EXW44_22810	COG3852	Histidine kinase
EXW44_22815	COG0753	catalase activity
EXW44_22820	COG2267	carboxylic ester hydrolase activity
EXW44_22830	COG1368	sulfuric ester hydrolase activity
EXW44_22840	COG4895	conserved protein (DUF2196)
EXW44_22855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW44_22860	COG1116	anion transmembrane transporter activity
EXW44_22865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW44_22890	COG0494	nUDIX hydrolase
EXW44_22930	COG2076	Multidrug Resistance protein
EXW44_22935	COG2076	Multidrug Resistance protein
EXW44_22940	COG0789	Transcriptional regulator
EXW44_22945	COG1854	S-ribosylhomocysteine lyase activity
EXW44_22955	COG0288	reversible hydration of carbon dioxide
EXW44_22960	COG1271	oxidase subunit
EXW44_22965	COG1294	oxidase, subunit
EXW44_22985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW44_23010	COG1842	Phage shock protein A
EXW44_23035	COG3859	Proton-coupled thiamine transporter YuaJ
EXW44_23040	COG5002	protein histidine kinase activity
EXW44_23045	COG0745	RESPONSE REGULATOR receiver
EXW44_23070	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW44_23075	COG1597	lipid kinase activity
EXW44_23110	COG1136	(ABC) transporter
EXW44_23140	COG5002	protein histidine kinase activity
EXW44_23150	COG0586	Pfam SNARE associated Golgi protein
EXW44_23165	COG0577	efflux transmembrane transporter activity
EXW44_23170	COG1136	(ABC) transporter
EXW44_23175	COG2207	Transcriptional regulator
EXW44_23175	COG3708	Transcriptional regulator
EXW44_23185	COG1131	(ABC) transporter
EXW44_23195	COG5658	integral membrane protein
EXW44_23200	COG0640	Transcriptional regulator
EXW44_23205	COG0745	RESPONSE REGULATOR receiver
EXW44_23210	COG2205	protein histidine kinase activity
EXW44_23215	COG0577	efflux transmembrane transporter activity
EXW44_23220	COG0577	efflux transmembrane transporter activity
EXW44_23225	COG1136	(ABC) transporter
EXW44_23230	COG0577	efflux transmembrane transporter activity
EXW44_23245	COG2188	Transcriptional regulator
EXW44_23265	COG3964	amidohydrolase
EXW44_23285	COG4948	Mandelate Racemase Muconate Lactonizing
EXW44_23290	COG0318	PFAM AMP-dependent synthetase and ligase
EXW44_23300	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW44_23310	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW44_23315	COG1169	isochorismate synthase
EXW44_23320	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW44_23325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW44_23330	COG1278	Cold shock
EXW44_23340	COG0789	Transcriptional regulator
EXW44_23350	COG0058	SHG alpha-glucan phosphorylase activity
EXW44_23360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW44_23365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW44_23370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW44_23405	COG1595	DNA-templated transcription, initiation
EXW44_23540	COG1285	pathogenesis
EXW44_23545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW44_23555	COG0166	Belongs to the GPI family
EXW44_23565	COG2155	Conserved Protein
EXW44_23570	COG1098	S1 RNA binding domain
EXW44_23575	COG0436	Aminotransferase
EXW44_23580	COG1522	sequence-specific DNA binding
EXW44_23585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW44_23590	COG2267	carboxylic ester hydrolase activity
EXW44_23600	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW44_23615	COG5018	Exonuclease
EXW44_23620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW44_23640	COG2050	protein possibly involved in aromatic compounds catabolism
EXW44_23650	COG1268	BioY protein
EXW44_23660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW44_23665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW44_23675	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW44_23680	COG3584	3D domain protein
EXW44_23695	COG1252	NADH dehydrogenase
EXW44_23700	COG0492	ferredoxin-NADP+ reductase activity
EXW44_23705	COG3708	Transcriptional regulator
EXW44_23720	COG1683	Conserved Protein
EXW44_23745	COG0316	Belongs to the HesB IscA family
EXW44_23750	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW44_23755	COG4844	belongs to the
EXW44_23760	COG1252	NADH dehydrogenase
EXW44_23770	COG0390	transport system, permease component
EXW44_23775	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW44_23810	COG4837	Protein of unknown function (DUF1462)
EXW44_23815	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW44_23825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW44_23830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW44_23845	COG1136	(ABC) transporter
EXW44_23845	COG0577	efflux transmembrane transporter activity
EXW44_23850	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW44_23860	COG0647	UMP catabolic process
EXW44_23870	COG2445	Protein of unknown function DUF86
EXW44_23875	COG1494	fructose-1,6-bisphosphatase
EXW44_23890	COG4470	Protein conserved in bacteria
EXW44_23900	COG0789	Transcriptional regulator
EXW44_23905	COG4377	Putative membrane peptidase family (DUF2324)
EXW44_23925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW44_23930	COG0739	heme binding
EXW44_23940	COG3377	Domain of unknown function (DUF1805)
EXW44_23945	COG0737	Belongs to the 5'-nucleotidase family
EXW44_23950	COG1695	Transcriptional regulator
EXW44_23960	COG0719	Fe-S assembly protein
EXW44_23965	COG0822	iron-sulfur transferase activity
EXW44_23970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW44_23975	COG0719	Fe-S assembly protein
EXW44_23980	COG0396	ATPase activity
EXW44_23985	COG1464	Belongs to the NlpA lipoprotein family
EXW44_23990	COG1464	Belongs to the NlpA lipoprotein family
EXW44_23995	COG2011	ABC-type metal ion transport system permease component
EXW44_24000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW44_24010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW44_24015	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW44_24020	COG0509	glycine decarboxylation via glycine cleavage system
EXW44_24025	COG1393	Belongs to the ArsC family
EXW44_24060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW44_24065	COG1960	acyl-CoA dehydrogenase activity
EXW44_24070	COG0183	Belongs to the thiolase family
EXW44_24075	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW44_24075	COG1024	Enoyl-CoA hydratase
EXW44_24085	COG1686	Belongs to the peptidase S11 family
EXW44_24090	COG0506	proline dehydrogenase activity
EXW44_24100	COG0011	TIGRFAM Protein of
EXW44_24105	COG0840	transmembrane signaling receptor activity
EXW44_24115	COG2814	Major facilitator Superfamily
EXW44_24120	COG0531	amino acid
EXW44_24145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW44_24195	COG0586	Pfam SNARE associated Golgi protein
EXW44_24205	COG1376	ErfK ybiS ycfS ynhG family protein
EXW44_24210	COG0745	RESPONSE REGULATOR receiver
EXW44_24215	COG5002	protein histidine kinase activity
EXW44_24225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW44_24240	COG0840	transmembrane signaling receptor activity
EXW44_24245	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW44_24250	COG3227	Zinc metalloprotease (Elastase)
EXW44_24255	COG1741	Belongs to the pirin family
EXW44_24270	COG0586	Pfam SNARE associated Golgi protein
EXW44_24275	COG0475	glutathione-regulated potassium exporter activity
EXW44_24280	COG0490	domain, Protein
EXW44_24285	COG1115	amino acid carrier protein
EXW44_24290	COG0783	Belongs to the Dps family
EXW44_24300	COG2318	DinB family
EXW44_24305	COG1611	Belongs to the LOG family
EXW44_24315	COG1528	Iron-storage protein
EXW44_24320	COG2311	Membrane
EXW44_24325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW44_24330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW44_24335	COG1115	amino acid carrier protein
EXW44_24340	COG2910	NAD(P)H-binding
EXW44_24355	COG0656	L-ascorbic acid biosynthetic process
EXW44_24360	COG2814	Major facilitator Superfamily
EXW44_24365	COG1733	regulation of RNA biosynthetic process
EXW44_24375	COG1252	NADH dehydrogenase
EXW44_24395	COG3290	protein histidine kinase activity
EXW44_24395	COG0840	transmembrane signaling receptor activity
EXW44_24430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW44_24445	COG4224	UPF0291 protein
EXW44_24450	COG1335	isochorismatase
EXW44_24455	COG1522	sequence-specific DNA binding
EXW44_24465	COG1522	sequence-specific DNA binding
EXW44_24470	COG0288	reversible hydration of carbon dioxide
EXW44_24475	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW44_24480	COG2233	PERMEase
EXW44_24520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW44_24525	COG0557	exoribonuclease II activity
EXW44_24530	COG1647	Serine aminopeptidase, S33
EXW44_24535	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW44_24540	COG1346	cytolysis
EXW44_24555	COG0148	phosphopyruvate hydratase activity
EXW44_24565	COG0149	triose-phosphate isomerase activity
EXW44_24570	COG0126	phosphoglycerate kinase activity
EXW44_24575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW44_24590	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW44_24625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW44_24640	COG2323	membrane
EXW44_24650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW44_24655	COG1481	regulation of sporulation
EXW44_24660	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW44_24665	COG1660	Displays ATPase and GTPase activities
EXW44_24670	COG1051	belongs to the nudix hydrolase family
EXW44_24680	COG0492	ferredoxin-NADP+ reductase activity
EXW44_24685	COG0457	Tetratricopeptide repeat
EXW44_24690	COG0110	maltose O-acetyltransferase activity
EXW44_24695	COG0546	phosphoglycolate phosphatase activity
EXW44_24700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW44_24705	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW44_24710	COG1950	PFAM Membrane protein of
EXW44_24715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW44_24735	COG0789	Transcriptional regulator
EXW44_24770	COG0583	DNA-binding transcription factor activity
EXW44_24775	COG0789	Transcriptional regulator
EXW44_24780	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW44_24785	COG0488	(ABC) transporter
EXW44_24795	COG1132	(ABC) transporter
EXW44_24800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW44_24805	COG3409	Peptidoglycan-binding domain 1 protein
EXW44_24805	COG0793	Belongs to the peptidase S41A family
EXW44_24810	COG2177	Part of the ABC transporter FtsEX involved in
EXW44_24815	COG2884	Cell division ATP-binding protein ftsE
EXW44_24850	COG1131	(ABC) transporter
EXW44_24885	COG1278	Cold shock
EXW44_24890	COG1040	competence protein
EXW44_24895	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW44_24900	COG0791	NLP P60 protein
EXW44_24900	COG1388	LysM domain
EXW44_24905	COG1733	regulation of RNA biosynthetic process
EXW44_24910	COG1307	EDD domain protein, DegV family
EXW44_24915	COG1739	Uncharacterized protein family UPF0029
EXW44_24920	COG1316	TRANSCRIPTIONal
EXW44_24925	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW44_24930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW44_24935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW44_24945	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW44_24945	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW44_24965	COG1486	melibiose metabolic process
EXW44_24970	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW44_24975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW44_25000	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW44_25010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW44_25015	COG1301	dicarboxylic acid transport
EXW44_25035	COG1511	domain protein
EXW44_25040	COG0583	DNA-binding transcription factor activity
EXW44_25045	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW44_25050	COG1271	oxidase subunit
EXW44_25055	COG1294	oxidase, subunit
EXW44_25060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW44_25065	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW44_25070	COG1620	l-lactate permease
EXW44_25080	COG2389	metal-binding protein
EXW44_25090	COG1368	sulfuric ester hydrolase activity
EXW44_25100	COG0791	NLP P60 protein
EXW44_25100	COG1388	LysM domain
EXW44_25105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW44_25115	COG1215	transferase activity, transferring glycosyl groups
EXW44_25120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW44_25130	COG3584	3D domain protein
EXW44_25130	COG1388	LysM domain
EXW44_25155	COG4715	Zinc finger, swim domain protein
EXW44_25160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW44_25200	COG0577	efflux transmembrane transporter activity
EXW44_25205	COG1136	(ABC) transporter
EXW44_25240	COG3850	Histidine kinase
EXW44_25240	COG5002	protein histidine kinase activity
EXW44_25245	COG0745	RESPONSE REGULATOR receiver
EXW44_25255	COG1316	TRANSCRIPTIONal
EXW44_25265	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW44_25285	COG0438	transferase activity, transferring glycosyl groups
EXW44_25295	COG1215	transferase activity, transferring glycosyl groups
EXW44_25305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW44_25310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW44_25315	COG1086	Polysaccharide biosynthesis protein
EXW44_25320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW44_25325	COG4464	protein tyrosine phosphatase activity
EXW44_25330	COG0489	protein tyrosine kinase activity
EXW44_25335	COG3944	biosynthesis protein
EXW44_25340	COG0489	protein tyrosine kinase activity
EXW44_25355	COG1609	Transcriptional regulator
EXW44_25365	COG0739	heme binding
EXW44_25380	COG3279	Response regulator of the LytR AlgR family
EXW44_25385	COG2385	sporulation resulting in formation of a cellular spore
EXW44_25400	COG4836	Membrane
EXW44_25405	COG1007	ATP synthesis coupled electron transport
EXW44_25410	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW44_25415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW44_25420	COG0713	ATP synthesis coupled electron transport
EXW44_25425	COG0839	Belongs to the complex I subunit 6 family
EXW44_25435	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW44_25440	COG0649	NAD binding
EXW44_25445	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW44_25450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW44_25455	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW44_25460	COG5001	Diguanylate cyclase
EXW44_25460	COG3300	MHYT domain
EXW44_25475	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW44_25480	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW44_25485	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW44_25490	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW44_25495	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW44_25500	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW44_25510	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW44_25535	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW44_25545	COG0698	ribose 5-phosphate isomerase
EXW44_25555	COG2190	(PTS) system
EXW44_25560	COG2259	Doxx family
EXW44_25565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW44_25580	COG1971	Probably functions as a manganese efflux pump
EXW44_25585	COG0009	L-threonylcarbamoyladenylate synthase
EXW44_25600	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW44_25605	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW44_25610	COG1435	thymidine kinase activity
EXW44_25620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW44_25630	COG1494	fructose-1,6-bisphosphatase
EXW44_25650	COG4821	SIS domain
EXW44_25655	COG0504	CTP synthase activity
EXW44_25660	COG3343	RNA polymerase activity
EXW44_25670	COG1960	acyl-CoA dehydrogenase activity
EXW44_25675	COG1960	acyl-CoA dehydrogenase activity
EXW44_25680	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW44_25685	COG0183	Belongs to the thiolase family
EXW44_25690	COG2181	nitrate reductase activity
EXW44_25690	COG0247	lactate metabolic process
EXW44_25695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW44_25700	COG4294	response to UV
EXW44_25705	COG3300	MHYT domain
EXW44_25705	COG5001	Diguanylate cyclase
EXW44_25720	COG3227	Zinc metalloprotease (Elastase)
EXW44_25725	COG2197	response regulator
EXW44_25730	COG4585	Histidine kinase
EXW44_25735	COG0842	Transport permease protein
EXW44_25740	COG1131	(ABC) transporter
EXW44_25745	COG0024	Methionine aminopeptidase
EXW44_25750	COG2234	aminopeptidase activity
EXW44_25765	COG4506	Protein conserved in bacteria
EXW44_25770	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW44_25785	COG0010	Belongs to the arginase family
EXW44_25790	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW44_25795	COG2814	Major facilitator Superfamily
EXW44_25800	COG0789	Transcriptional regulator
EXW44_25805	COG0584	glycerophosphoryl diester phosphodiesterase
EXW44_25810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW44_25820	COG1994	Peptidase M50
EXW44_25830	COG1078	dGTPase activity
EXW44_25835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW44_25840	COG1120	ATPase activity
EXW44_25845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW44_25850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW44_25855	COG4844	belongs to the
EXW44_25870	COG0280	phosphate acetyltransferase
EXW44_25875	COG3253	May function as heme-dependent peroxidase
EXW44_25885	COG3773	Cell wall hydrolase
EXW44_25895	COG2363	Small membrane protein
EXW44_25910	COG2233	PERMEase
EXW44_25915	COG0561	phosphatase activity
EXW44_25920	COG2814	Major facilitator Superfamily
EXW44_25925	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW44_25930	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW44_25935	COG1131	(ABC) transporter
EXW44_25940	COG2755	lipolytic protein G-D-S-L family
EXW44_25945	COG1609	Transcriptional regulator
EXW44_25955	COG0460	homoserine dehydrogenase
EXW44_25960	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW44_25965	COG2873	o-acetylhomoserine
EXW44_25985	COG2197	response regulator
EXW44_25990	COG2203	Gaf domain
EXW44_25990	COG4585	Histidine kinase
EXW44_25995	COG0351	phosphomethylpyrimidine kinase
EXW44_26000	COG3706	GGDEF domain
EXW44_26005	COG2879	small protein
EXW44_26010	COG1966	Carbon starvation protein
EXW44_26015	COG3279	Response regulator of the LytR AlgR family
EXW44_26020	COG0477	Major facilitator Superfamily
EXW44_26045	COG0840	transmembrane signaling receptor activity
EXW44_26055	COG1607	acyl-coa hydrolase
EXW44_26060	COG1216	Glycosyl transferase, family 2
EXW44_26070	COG1216	Glycosyl transferase, family 2
EXW44_26080	COG4485	Bacterial membrane protein, YfhO
EXW44_26085	COG0463	Glycosyl transferase, family 2
EXW44_26095	COG1309	transcriptional regulator
EXW44_26100	COG0488	(ABC) transporter
EXW44_26105	COG1309	transcriptional regulator
EXW44_26110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW44_26115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW44_26115	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW44_26120	COG0628	permease
EXW44_26130	COG1380	Effector of murein hydrolase LrgA
EXW44_26135	COG3279	Response regulator of the LytR AlgR family
EXW44_26140	COG3275	phosphorelay sensor kinase activity
EXW44_26145	COG2814	Major facilitator Superfamily
EXW44_26150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW44_26155	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW44_26165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW44_26215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW44_26220	COG1272	protein, Hemolysin III
EXW44_26245	COG1164	Oligoendopeptidase f
EXW44_26255	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW44_26265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW44_26270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW44_26275	COG4853	Protein conserved in bacteria
EXW44_26285	COG5002	protein histidine kinase activity
EXW44_26290	COG0745	RESPONSE REGULATOR receiver
EXW44_26320	COG0305	Participates in initiation and elongation during chromosome replication
EXW44_26325	COG0359	binds to the 23S rRNA
EXW44_26330	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW44_26335	COG4241	membrane
EXW44_26345	COG0629	single-stranded DNA binding
EXW44_26350	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW44_26355	COG0012	GTP binding
EXW44_26360	COG4481	Protein conserved in bacteria
EXW44_26365	COG0668	transmembrane transport
EXW44_26375	COG1475	DNA binding
EXW44_26380	COG1192	Involved in chromosome partitioning
EXW44_26385	COG1475	DNA binding
EXW44_26390	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW44_26395	COG0445	tRNA wobble uridine modification
EXW44_26400	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW44_26405	COG1847	R3H domain protein
EXW44_26410	COG0706	membrane insertase activity
EXW44_26415	COG0594	ribonuclease P activity
EXW44_26420	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW44_26425	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW44_26430	COG0592	DNA-directed DNA polymerase activity
EXW44_26435	COG2501	S4 domain
EXW44_26440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW44_26445	COG0187	DNA topoisomerase II activity
EXW44_26450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW44_26485	COG0517	IMP dehydrogenase activity
EXW44_26485	COG0516	GMP reductase activity
EXW44_26490	COG1686	Belongs to the peptidase S11 family
EXW44_26495	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW44_26500	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW44_26520	COG1428	Deoxynucleoside kinase
EXW44_26525	COG1428	Deoxynucleoside kinase
EXW44_26530	COG1335	isochorismatase
EXW44_26535	COG0590	tRNA wobble adenosine to inosine editing
EXW44_26545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW44_26550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW44_26555	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW44_26600	COG1982	Orn Lys Arg decarboxylase major
EXW44_26605	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW44_26610	COG0470	DNA polymerase III
EXW44_26615	COG1774	PSP1 C-terminal conserved region
EXW44_26620	COG4467	Involved in initiation control of chromosome replication
EXW44_26625	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW44_26635	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW44_26640	COG2002	toxin-antitoxin pair type II binding
EXW44_26650	COG0084	hydrolase, TatD family'
EXW44_26660	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW44_26670	COG4466	Protein conserved in bacteria
EXW44_26680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW44_26685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW44_26690	COG0251	oxidation-reduction process
EXW44_26695	COG2088	sporulation resulting in formation of a cellular spore
EXW44_26700	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW44_26720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW44_26725	COG2002	toxin-antitoxin pair type II binding
EXW44_26730	COG2244	polysaccharide biosynthetic process
EXW44_26735	COG3956	TIGRFAM MazG family protein
EXW44_26740	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW44_26760	COG1098	S1 RNA binding domain
EXW44_26775	COG2208	phosphoserine phosphatase activity
EXW44_26785	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW44_26790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW44_26795	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW44_26800	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW44_26805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW44_26810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW44_26815	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW44_26820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW44_26825	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW44_26830	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW44_26835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW44_26840	COG1396	sequence-specific DNA binding
EXW44_26845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW44_26850	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW44_26935	COG3880	PFAM UvrB UvrC protein
EXW44_26940	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW44_26945	COG0542	response to heat
EXW44_26950	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW44_26955	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW44_26960	COG4956	integral membrane protein (PIN domain superfamily)
EXW44_26965	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW44_26975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW44_26980	COG1045	serine acetyltransferase
EXW44_26985	COG0215	cysteine-tRNA ligase activity
EXW44_26995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW44_27000	COG3688	RNA-binding protein containing a PIN domain
EXW44_27010	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW44_27015	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW44_27020	COG0250	Participates in transcription elongation, termination and antitermination
EXW44_27025	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW44_27030	COG0081	regulation of translation
EXW44_27035	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW44_27040	COG0222	ribosome binding
EXW44_27045	COG2813	Specifically methylates the guanine in position
EXW44_27050	COG0085	RNA polymerase activity
EXW44_27055	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW44_27060	COG1358	cellular component organization or biogenesis
EXW44_27065	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW44_27075	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW44_27080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW44_27085	COG0051	transcription antitermination factor activity, RNA binding
EXW44_27090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW44_27095	COG0088	Forms part of the polypeptide exit tunnel
EXW44_27100	COG0089	rRNA binding
EXW44_27105	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW44_27110	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW44_27115	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW44_27130	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW44_27135	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW44_27145	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW44_27150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW44_27160	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW44_27170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW44_27180	COG1841	ribosomal large subunit assembly
EXW44_27185	COG0200	Binds to the 23S rRNA
EXW44_27190	COG0201	protein transport
EXW44_27195	COG0563	adenylate kinase activity
EXW44_27200	COG0024	Methionine aminopeptidase
EXW44_27210	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW44_27215	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW44_27220	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW44_27245	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW44_27255	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW44_27260	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW44_27270	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW44_27275	COG0489	protein tyrosine kinase activity
EXW44_27285	COG2194	sulfuric ester hydrolase activity
EXW44_27290	COG0726	polysaccharide deacetylase
EXW44_27370	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW44_27375	COG4856	YbbR-like protein
EXW44_27380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW44_27410	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_27415	COG2011	ABC-type metal ion transport system permease component
EXW44_27425	COG1464	Belongs to the NlpA lipoprotein family
EXW44_27430	COG0604	alcohol dehydrogenase
EXW44_27440	COG0277	FAD linked oxidase domain protein
EXW44_27445	COG2271	Major facilitator Superfamily
EXW44_27455	COG2814	Major facilitator Superfamily
EXW44_27470	COG0601	transmembrane transport
EXW44_27475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW44_27480	COG0444	Belongs to the ABC transporter superfamily
EXW44_27485	COG4608	Belongs to the ABC transporter superfamily
EXW44_27490	COG4166	transmembrane transport
EXW44_27515	COG4166	transmembrane transport
EXW44_27520	COG4166	transmembrane transport
EXW44_27525	COG0656	L-ascorbic acid biosynthetic process
EXW44_27545	COG4149	molybdate abc transporter
EXW44_27550	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW44_27555	COG1910	domain protein
EXW44_27570	COG0697	spore germination
EXW44_27585	COG0204	Acyl-transferase
EXW44_27595	COG1609	Transcriptional regulator
EXW44_27605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW44_27620	COG5298	Protein conserved in bacteria
EXW44_27645	COG0488	(ABC) transporter
EXW44_27650	COG4585	Histidine kinase
EXW44_27655	COG2197	response regulator
EXW44_27660	COG1131	(ABC) transporter
EXW44_27665	COG0842	Transport permease protein
EXW44_27665	COG1511	domain protein
EXW44_27670	COG0842	Transport permease protein
EXW44_27680	COG0747	negative chemotaxis
EXW44_27690	COG0601	transmembrane transport
EXW44_27695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW44_27700	COG0444	Belongs to the ABC transporter superfamily
EXW44_27705	COG4608	Belongs to the ABC transporter superfamily
EXW44_27710	COG0561	phosphatase activity
EXW44_27740	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW44_27745	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW44_27755	COG0531	amino acid
EXW44_27760	COG2814	Major facilitator Superfamily
EXW44_27770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW44_27780	COG4294	response to UV
EXW44_27785	COG0705	Rhomboid family
EXW44_27790	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW44_27795	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW44_27805	COG0864	Transcriptional regulator
EXW44_27810	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW44_27815	COG2183	response to ionizing radiation
EXW44_27915	COG0802	atpase or kinase
EXW44_27920	COG1214	PFAM Peptidase M22, glycoprotease
EXW44_27925	COG0456	acetyltransferase
EXW44_27935	COG0488	(ABC) transporter
EXW44_27940	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW44_27950	COG1266	CAAX protease self-immunity
EXW44_27955	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW44_27960	COG0459	protein refolding
EXW44_27965	COG0519	Catalyzes the synthesis of GMP from XMP
EXW44_27965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW44_27970	COG2252	PERMEase
EXW44_27980	COG5002	protein histidine kinase activity
EXW44_28000	COG1028	Short-chain dehydrogenase reductase Sdr
EXW44_28055	COG0673	inositol 2-dehydrogenase activity
EXW44_28060	COG0673	inositol 2-dehydrogenase activity
EXW44_28065	COG2169	Transcriptional regulator
EXW44_28310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW44_28320	COG0662	Cupin 2, conserved barrel domain protein
EXW44_28320	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EXW44_28385	COG3344	reverse transcriptase
EXW44_28410	COG2311	Membrane
EXW44_28445	COG1696	Membrane protein involved in D-alanine export
EXW44_28465	COG0745	RESPONSE REGULATOR receiver
EXW44_28490	COG1279	arginine transmembrane transporter activity
EXW44_28495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW44_28500	COG1175	transmembrane transport
EXW44_28505	COG0395	ABC-type sugar transport system, permease component
EXW44_28530	COG3842	ATPase activity
EXW44_28535	COG5002	protein histidine kinase activity
EXW44_28545	COG1136	(ABC) transporter
EXW44_28560	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW44_28570	COG2707	UPF0756 membrane protein
EXW44_28580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW44_28715	COG2814	Major facilitator Superfamily
EXW44_28845	COG4977	sequence-specific DNA binding
EXW44_28860	COG0083	homoserine kinase activity
EXW44_28880	COG1309	transcriptional regulator
EXW44_28885	COG2814	Major facilitator Superfamily
EXW44_28895	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW44_28895	COG2508	Transcriptional regulator
EXW44_28900	COG0686	Belongs to the AlaDH PNT family
EXW44_28970	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW44_29025	COG1396	sequence-specific DNA binding
EXW44_29045	COG0840	transmembrane signaling receptor activity
EXW44_29050	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW44_29070	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW44_29075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW44_29080	COG0772	Belongs to the SEDS family
EXW44_29085	COG2239	Acts as a magnesium transporter
EXW44_29095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW44_29110	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW44_29115	COG0519	Catalyzes the synthesis of GMP from XMP
EXW44_29125	COG1278	Cold shock
EXW44_29145	COG0024	Methionine aminopeptidase
EXW44_29180	COG4974	Belongs to the 'phage' integrase family
EXW44_29275	COG2357	RelA SpoT domain protein
EXW44_29280	COG2814	Major facilitator Superfamily
EXW44_29335	COG0776	regulation of translation
EXW44_29375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW44_29395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW44_29425	COG3344	reverse transcriptase
EXW44_29475	COG0640	Transcriptional regulator
EXW44_29490	COG0457	Tetratricopeptide repeat
EXW44_29540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW44_29550	COG2040	homocysteine
EXW44_29555	COG0833	amino acid
EXW44_29655	COG1725	Transcriptional regulator
EXW44_29660	COG1131	(ABC) transporter
EXW44_29705	COG1329	Transcriptional regulator
EXW44_29775	COG0457	Tetratricopeptide repeat
EXW44_29805	COG1132	(ABC) transporter
EXW44_29855	COG1396	sequence-specific DNA binding
EXW44_29905	COG0653	protein targeting
EXW44_30020	COG0367	asparagine synthase
EXW44_30110	COG0542	response to heat
EXW44_30120	COG3397	chitin binding
EXW44_30195	COG1132	(ABC) transporter
EXW44_30250	COG1404	Belongs to the peptidase S8 family
EXW44_30260	COG2814	Major facilitator Superfamily
EXW44_30265	COG2234	aminopeptidase activity
EXW44_30275	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW44_30290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW44_30295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW44_30300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW44_30310	COG0456	acetyltransferase
EXW44_30350	COG1956	GAF domain-containing protein
EXW44_30435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW44_30435	COG0551	DNA topoisomerase type I activity
EXW44_30505	COG1388	LysM domain
EXW44_30560	COG0463	Glycosyl transferase, family 2
EXW44_30585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW44_30590	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW44_30595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW44_30600	COG0438	transferase activity, transferring glycosyl groups
EXW44_30620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW44_30625	COG0438	transferase activity, transferring glycosyl groups
EXW44_30630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW44_30715	COG3773	Cell wall hydrolase
EXW44_30795	COG4166	transmembrane transport
EXW44_30860	COG0582	viral genome integration into host DNA
EXW44_30870	COG3620	sequence-specific DNA binding
EXW44_30890	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis