locus-tag	class	description
EXW39_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW39_00010	COG0592	DNA-directed DNA polymerase activity
EXW39_00015	COG2501	S4 domain
EXW39_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW39_00025	COG0187	DNA topoisomerase II activity
EXW39_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW39_00065	COG0517	IMP dehydrogenase activity
EXW39_00065	COG0516	GMP reductase activity
EXW39_00070	COG1686	Belongs to the peptidase S11 family
EXW39_00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW39_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW39_00100	COG1428	Deoxynucleoside kinase
EXW39_00105	COG1428	Deoxynucleoside kinase
EXW39_00110	COG1335	isochorismatase
EXW39_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW39_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW39_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW39_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW39_00180	COG1982	Orn Lys Arg decarboxylase major
EXW39_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW39_00190	COG0470	DNA polymerase III
EXW39_00195	COG1774	PSP1 C-terminal conserved region
EXW39_00200	COG4467	Involved in initiation control of chromosome replication
EXW39_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW39_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW39_00220	COG2002	toxin-antitoxin pair type II binding
EXW39_00230	COG0084	hydrolase, TatD family'
EXW39_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW39_00250	COG4466	Protein conserved in bacteria
EXW39_00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW39_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW39_00270	COG0251	oxidation-reduction process
EXW39_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW39_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW39_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW39_00305	COG2002	toxin-antitoxin pair type II binding
EXW39_00310	COG2244	polysaccharide biosynthetic process
EXW39_00315	COG3956	TIGRFAM MazG family protein
EXW39_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW39_00340	COG1098	S1 RNA binding domain
EXW39_00355	COG2208	phosphoserine phosphatase activity
EXW39_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW39_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW39_00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW39_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW39_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW39_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW39_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW39_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW39_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW39_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW39_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW39_00420	COG1396	sequence-specific DNA binding
EXW39_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW39_00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW39_00520	COG3880	PFAM UvrB UvrC protein
EXW39_00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW39_00530	COG0542	response to heat
EXW39_00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW39_00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW39_00545	COG4956	integral membrane protein (PIN domain superfamily)
EXW39_00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW39_00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW39_00565	COG1045	serine acetyltransferase
EXW39_00570	COG0215	cysteine-tRNA ligase activity
EXW39_00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW39_00585	COG3688	RNA-binding protein containing a PIN domain
EXW39_00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW39_00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW39_00605	COG0250	Participates in transcription elongation, termination and antitermination
EXW39_00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW39_00615	COG0081	regulation of translation
EXW39_00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW39_00625	COG0222	ribosome binding
EXW39_00630	COG2813	Specifically methylates the guanine in position
EXW39_00635	COG0085	RNA polymerase activity
EXW39_00640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW39_00645	COG1358	cellular component organization or biogenesis
EXW39_00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW39_00660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW39_00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW39_00670	COG0051	transcription antitermination factor activity, RNA binding
EXW39_00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW39_00680	COG0088	Forms part of the polypeptide exit tunnel
EXW39_00685	COG0089	rRNA binding
EXW39_00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW39_00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW39_00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW39_00715	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW39_00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW39_00730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW39_00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW39_00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW39_00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW39_00765	COG1841	ribosomal large subunit assembly
EXW39_00770	COG0200	Binds to the 23S rRNA
EXW39_00775	COG0201	protein transport
EXW39_00780	COG0563	adenylate kinase activity
EXW39_00785	COG0024	Methionine aminopeptidase
EXW39_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW39_00800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW39_00805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW39_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW39_00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW39_00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW39_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW39_00860	COG0489	protein tyrosine kinase activity
EXW39_00870	COG2194	sulfuric ester hydrolase activity
EXW39_00875	COG0726	polysaccharide deacetylase
EXW39_00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW39_00960	COG4856	YbbR-like protein
EXW39_00965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW39_00980	COG4946	Tricorn protease homolog
EXW39_00980	COG1506	peptidase
EXW39_00980	COG0823	Involved in the tonB-independent uptake of proteins
EXW39_00995	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_01000	COG2011	ABC-type metal ion transport system permease component
EXW39_01010	COG1464	Belongs to the NlpA lipoprotein family
EXW39_01015	COG0604	alcohol dehydrogenase
EXW39_01025	COG0277	FAD linked oxidase domain protein
EXW39_01030	COG2271	Major facilitator Superfamily
EXW39_01040	COG2814	Major facilitator Superfamily
EXW39_01055	COG0601	transmembrane transport
EXW39_01060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW39_01065	COG0444	Belongs to the ABC transporter superfamily
EXW39_01070	COG4608	Belongs to the ABC transporter superfamily
EXW39_01075	COG4166	transmembrane transport
EXW39_01085	COG2207	Transcriptional regulator
EXW39_01100	COG4166	transmembrane transport
EXW39_01105	COG4166	transmembrane transport
EXW39_01110	COG0656	L-ascorbic acid biosynthetic process
EXW39_01115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW39_01130	COG4149	molybdate abc transporter
EXW39_01135	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW39_01140	COG1910	domain protein
EXW39_01155	COG0697	spore germination
EXW39_01170	COG0204	Acyl-transferase
EXW39_01180	COG1609	Transcriptional regulator
EXW39_01190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW39_01205	COG5298	Protein conserved in bacteria
EXW39_01230	COG0488	(ABC) transporter
EXW39_01240	COG0747	negative chemotaxis
EXW39_01250	COG0601	transmembrane transport
EXW39_01255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW39_01260	COG0444	Belongs to the ABC transporter superfamily
EXW39_01265	COG4608	Belongs to the ABC transporter superfamily
EXW39_01270	COG0561	phosphatase activity
EXW39_01295	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW39_01300	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW39_01310	COG2814	Major facilitator Superfamily
EXW39_01320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW39_01330	COG4294	response to UV
EXW39_01335	COG0705	Rhomboid family
EXW39_01340	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW39_01345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW39_01350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW39_01355	COG0864	Transcriptional regulator
EXW39_01360	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW39_01365	COG2183	response to ionizing radiation
EXW39_01465	COG0802	atpase or kinase
EXW39_01470	COG1214	PFAM Peptidase M22, glycoprotease
EXW39_01475	COG0456	acetyltransferase
EXW39_01485	COG0488	(ABC) transporter
EXW39_01490	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW39_01500	COG1266	CAAX protease self-immunity
EXW39_01505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW39_01510	COG0459	protein refolding
EXW39_01515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW39_01515	COG0519	Catalyzes the synthesis of GMP from XMP
EXW39_01520	COG2252	PERMEase
EXW39_01530	COG5002	protein histidine kinase activity
EXW39_01555	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW39_01620	COG2205	protein histidine kinase activity
EXW39_01625	COG0745	RESPONSE REGULATOR receiver
EXW39_01650	COG0697	spore germination
EXW39_01680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW39_01685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW39_01690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW39_01695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW39_01700	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW39_01705	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW39_01710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW39_01715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW39_01720	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW39_01725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW39_01730	COG0138	bifunctional purine biosynthesis protein purh
EXW39_01735	COG0151	Belongs to the GarS family
EXW39_01760	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW39_01765	COG0210	DNA helicase
EXW39_01770	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW39_01775	COG4851	CamS sex pheromone cAM373 precursor
EXW39_01785	COG1012	belongs to the aldehyde dehydrogenase family
EXW39_01790	COG1335	isochorismatase
EXW39_01800	COG2011	ABC-type metal ion transport system permease component
EXW39_01805	COG1464	Belongs to the NlpA lipoprotein family
EXW39_01820	COG0003	Pfam Anion-transporting ATPase
EXW39_01825	COG1846	Transcriptional regulator
EXW39_01830	COG4682	membrane
EXW39_01840	COG0154	amidase activity
EXW39_01845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW39_01850	COG1597	lipid kinase activity
EXW39_01860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW39_01875	COG1012	belongs to the aldehyde dehydrogenase family
EXW39_01880	COG2076	Multidrug Resistance protein
EXW39_01885	COG2309	aminopeptidase activity
EXW39_01900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW39_01910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW39_01915	COG5002	protein histidine kinase activity
EXW39_01920	COG4807	Protein conserved in bacteria
EXW39_01945	COG1757	Na H antiporter
EXW39_01950	COG1473	amidohydrolase
EXW39_01965	COG0450	alkyl hydroperoxide reductase
EXW39_01975	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW39_01985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW39_01990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW39_01995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW39_02005	COG0492	ferredoxin-NADP+ reductase activity
EXW39_02020	COG0166	Belongs to the GPI family
EXW39_02045	COG5002	protein histidine kinase activity
EXW39_02065	COG3541	Predicted nucleotidyltransferase
EXW39_02075	COG2814	Major facilitator Superfamily
EXW39_02080	COG0723	plastoquinol--plastocyanin reductase activity
EXW39_02080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW39_02090	COG0765	amino acid transport
EXW39_02095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW39_02105	COG0840	transmembrane signaling receptor activity
EXW39_02110	COG0277	FAD linked oxidase domain protein
EXW39_02115	COG0366	Alpha amylase catalytic
EXW39_02120	COG2190	(PTS) system
EXW39_02120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW39_02120	COG1263	PTS System
EXW39_02140	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW39_02145	COG0352	thiamine-phosphate diphosphorylase activity
EXW39_02150	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW39_02170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW39_02175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW39_02180	COG1116	anion transmembrane transporter activity
EXW39_02185	COG0488	(ABC) transporter
EXW39_02230	COG2270	Major facilitator Superfamily
EXW39_02260	COG2310	stress, protein
EXW39_02265	COG2310	stress, protein
EXW39_02270	COG2310	stress, protein
EXW39_02275	COG0861	Integral membrane protein TerC family
EXW39_02285	COG3853	Toxic anion resistance protein (TelA)
EXW39_02295	COG4840	Belongs to the UPF0435 family
EXW39_02300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW39_02310	COG1295	ribonuclease BN
EXW39_02315	COG2217	Heavy metal translocating P-type atpase
EXW39_02320	COG0697	spore germination
EXW39_02340	COG0586	Pfam SNARE associated Golgi protein
EXW39_02355	COG3871	stress protein (general stress protein 26)
EXW39_02360	COG0387	Pfam Sodium calcium exchanger
EXW39_02370	COG0535	radical SAM domain protein
EXW39_02390	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW39_02410	COG3829	transcription factor binding
EXW39_02420	COG0833	amino acid
EXW39_02425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW39_02445	COG2066	Belongs to the glutaminase family
EXW39_02455	COG1263	PTS System
EXW39_02455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW39_02460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW39_02475	COG1216	Glycosyl transferase, family 2
EXW39_02485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW39_02485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW39_02490	COG0463	Glycosyl transferase, family 2
EXW39_02505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW39_02510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW39_02525	COG1228	amidohydrolase
EXW39_02530	COG1090	epimerase
EXW39_02535	COG2137	regulation of response to DNA damage stimulus
EXW39_02560	COG1988	membrane-bound metal-dependent
EXW39_02565	COG1194	a g-specific adenine glycosylase
EXW39_02580	COG3557	Belongs to the UPF0374 family
EXW39_02585	COG1132	(ABC) transporter
EXW39_02590	COG4129	membrane
EXW39_02600	COG0067	glutamate synthase
EXW39_02600	COG0069	glutamate synthase activity
EXW39_02600	COG0070	glutamate synthase
EXW39_02605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW39_02610	COG4555	ABC transporter
EXW39_02630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW39_02635	COG0735	belongs to the Fur family
EXW39_02755	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW39_02760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW39_02780	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW39_02790	COG2766	serine protein kinase
EXW39_02795	COG2718	Belongs to the UPF0229 family
EXW39_02805	COG0456	acetyltransferase
EXW39_02810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW39_02820	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW39_02825	COG2268	Band 7 protein
EXW39_02835	COG3290	protein histidine kinase activity
EXW39_02840	COG4565	transcriptional regulatory protein
EXW39_02845	COG2851	Citrate transporter
EXW39_02875	COG3842	ATPase activity
EXW39_02880	COG1175	transmembrane transport
EXW39_02885	COG0395	ABC-type sugar transport system, permease component
EXW39_02895	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW39_02900	COG0745	RESPONSE REGULATOR receiver
EXW39_02905	COG5002	protein histidine kinase activity
EXW39_02915	COG4990	cell redox homeostasis
EXW39_02925	COG3290	protein histidine kinase activity
EXW39_02930	COG4565	transcriptional regulatory protein
EXW39_02935	COG3493	citrate carrier protein
EXW39_02940	COG0281	malic enzyme
EXW39_02950	COG0697	spore germination
EXW39_02955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW39_02965	COG5002	protein histidine kinase activity
EXW39_02970	COG0745	RESPONSE REGULATOR receiver
EXW39_02975	COG0456	acetyltransferase
EXW39_02980	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW39_02985	COG3383	formate dehydrogenase (NAD+) activity
EXW39_02990	COG2427	Protein of unknown function (DUF1641)
EXW39_03005	COG0531	amino acid
EXW39_03015	COG0640	Transcriptional regulator
EXW39_03020	COG2217	Heavy metal translocating P-type atpase
EXW39_03025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW39_03035	COG3227	Zinc metalloprotease (Elastase)
EXW39_03055	COG2720	vancomycin resistance protein
EXW39_03060	COG1316	TRANSCRIPTIONal
EXW39_03065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW39_03070	COG0346	lactoylglutathione lyase activity
EXW39_03075	COG1253	flavin adenine dinucleotide binding
EXW39_03080	COG1027	Aspartate ammonia-lyase
EXW39_03085	COG1620	l-lactate permease
EXW39_03090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW39_03110	COG3104	oligopeptide transport
EXW39_03115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW39_03120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW39_03125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW39_03140	COG0156	8-amino-7-oxononanoate synthase activity
EXW39_03145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW39_03155	COG4548	von Willebrand factor, type A
EXW39_03160	COG0714	Associated with various cellular activities
EXW39_03180	COG0531	amino acid
EXW39_03185	COG2188	Transcriptional regulator
EXW39_03190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW39_03190	COG1263	PTS System
EXW39_03195	COG0366	Alpha amylase catalytic
EXW39_03210	COG0697	spore germination
EXW39_03215	COG4585	Histidine kinase
EXW39_03220	COG2197	response regulator
EXW39_03225	COG1404	Belongs to the peptidase S8 family
EXW39_03240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW39_03245	COG1115	amino acid carrier protein
EXW39_03250	COG1126	abc transporter atp-binding protein
EXW39_03255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW39_03260	COG0765	amino acid transport
EXW39_03265	COG0765	amino acid transport
EXW39_03270	COG0833	amino acid
EXW39_03295	COG2378	regulation of single-species biofilm formation
EXW39_03300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW39_03305	COG5002	protein histidine kinase activity
EXW39_03320	COG0659	secondary active sulfate transmembrane transporter activity
EXW39_03345	COG0601	transmembrane transport
EXW39_03350	COG4608	Belongs to the ABC transporter superfamily
EXW39_03360	COG2271	Major facilitator Superfamily
EXW39_03365	COG1846	Transcriptional regulator
EXW39_03370	COG0477	Major facilitator Superfamily
EXW39_03375	COG1609	Transcriptional regulator
EXW39_03380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW39_03385	COG1869	D-ribose catabolic process
EXW39_03395	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW39_03400	COG1879	ABC-type sugar transport system periplasmic component
EXW39_03430	COG1063	alcohol dehydrogenase
EXW39_03445	COG3568	Endonuclease Exonuclease Phosphatase
EXW39_03475	COG0840	transmembrane signaling receptor activity
EXW39_03480	COG3583	domain protein
EXW39_03480	COG3584	3D domain protein
EXW39_03485	COG1476	TRANSCRIPTIONal
EXW39_03505	COG3104	oligopeptide transport
EXW39_03510	COG1114	Component of the transport system for branched-chain amino acids
EXW39_03525	COG1113	amino acid transport
EXW39_03530	COG2252	PERMEase
EXW39_03545	COG2153	protein acetylation
EXW39_03555	COG0569	domain protein
EXW39_03555	COG0475	glutathione-regulated potassium exporter activity
EXW39_03565	COG1845	cytochrome c oxidase, subunit III
EXW39_03570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW39_03580	COG0833	amino acid
EXW39_03585	COG4990	cell redox homeostasis
EXW39_03600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW39_03605	COG0697	spore germination
EXW39_03610	COG0531	amino acid
EXW39_03620	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW39_03625	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW39_03635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW39_03640	COG0573	inorganic phosphate transmembrane transporter activity
EXW39_03645	COG0581	inorganic phosphate transmembrane transporter activity
EXW39_03655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW39_03775	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW39_03790	COG4991	sh3 domain protein
EXW39_03790	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW39_03790	COG3103	Sh3 type 3 domain protein
EXW39_03795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW39_03800	COG1116	anion transmembrane transporter activity
EXW39_03805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW39_03810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW39_03815	COG0352	thiamine-phosphate diphosphorylase activity
EXW39_03820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW39_03825	COG2104	thiamine diphosphate biosynthetic process
EXW39_03835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW39_03840	COG0351	phosphomethylpyrimidine kinase
EXW39_03870	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW39_03875	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW39_03880	COG2205	protein histidine kinase activity
EXW39_03890	COG2252	PERMEase
EXW39_03895	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_03955	COG0778	Nitroreductase
EXW39_03960	COG2719	SpoVR family
EXW39_03965	COG1401	restriction endodeoxyribonuclease activity
EXW39_03990	COG1937	Protein conserved in bacteria
EXW39_03995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW39_03995	COG0425	Belongs to the sulfur carrier protein TusA family
EXW39_04000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW39_04000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW39_04005	COG0425	Belongs to the sulfur carrier protein TusA family
EXW39_04010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW39_04010	COG0425	Belongs to the sulfur carrier protein TusA family
EXW39_04015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW39_04020	COG2210	Belongs to the sulfur carrier protein TusA family
EXW39_04025	COG0730	response to heat
EXW39_04035	COG1316	TRANSCRIPTIONal
EXW39_04040	COG0604	alcohol dehydrogenase
EXW39_04045	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW39_04055	COG2814	Major facilitator Superfamily
EXW39_04070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW39_04070	COG3711	transcriptional antiterminator
EXW39_04075	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW39_04080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW39_04100	COG1388	LysM domain
EXW39_04100	COG3584	3D domain protein
EXW39_04105	COG0577	efflux transmembrane transporter activity
EXW39_04110	COG1136	(ABC) transporter
EXW39_04120	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW39_04130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW39_04135	COG0577	efflux transmembrane transporter activity
EXW39_04140	COG1114	Component of the transport system for branched-chain amino acids
EXW39_04145	COG3546	catalase activity
EXW39_04175	COG0586	Pfam SNARE associated Golgi protein
EXW39_04205	COG0531	amino acid
EXW39_04210	COG0475	glutathione-regulated potassium exporter activity
EXW39_04220	COG1737	Transcriptional regulator
EXW39_04225	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW39_04230	COG1263	PTS System
EXW39_04230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW39_04240	COG2259	Doxx family
EXW39_04265	COG1522	sequence-specific DNA binding
EXW39_04275	COG0300	oxidoreductase activity
EXW39_04290	COG2076	Multidrug Resistance protein
EXW39_04295	COG1309	transcriptional regulator
EXW39_04300	COG2814	Major facilitator Superfamily
EXW39_04305	COG1733	regulation of RNA biosynthetic process
EXW39_04330	COG0693	protein deglycase activity
EXW39_04340	COG0531	amino acid
EXW39_04345	COG1012	belongs to the aldehyde dehydrogenase family
EXW39_04355	COG1132	(ABC) transporter
EXW39_04360	COG1132	(ABC) transporter
EXW39_04365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW39_04370	COG0765	amino acid transport
EXW39_04375	COG1126	abc transporter atp-binding protein
EXW39_04390	COG0189	ligase activity
EXW39_04400	COG4399	Belongs to the UPF0754 family
EXW39_04405	COG3679	Belongs to the UPF0342 family
EXW39_04420	COG0028	Belongs to the TPP enzyme family
EXW39_04425	COG3527	Alpha-acetolactate decarboxylase
EXW39_04430	COG0463	Glycosyl transferase, family 2
EXW39_04435	COG1216	Glycosyl transferase, family 2
EXW39_04440	COG2094	Belongs to the DNA glycosylase MPG family
EXW39_04445	COG0561	phosphatase activity
EXW39_04455	COG3409	Peptidoglycan-binding domain 1 protein
EXW39_04455	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW39_04460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW39_04465	COG0318	PFAM AMP-dependent synthetase and ligase
EXW39_04470	COG0586	Pfam SNARE associated Golgi protein
EXW39_04480	COG0789	Transcriptional regulator
EXW39_04480	COG4978	Transcriptional regulator
EXW39_04490	COG0659	secondary active sulfate transmembrane transporter activity
EXW39_04495	COG2244	polysaccharide biosynthetic process
EXW39_04515	COG1024	Enoyl-CoA hydratase
EXW39_04535	COG1363	Peptidase, m42
EXW39_04555	COG2318	DinB family
EXW39_04575	COG0579	oxidoreductase
EXW39_04615	COG0601	transmembrane transport
EXW39_04620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW39_04625	COG0444	Belongs to the ABC transporter superfamily
EXW39_04630	COG4608	Belongs to the ABC transporter superfamily
EXW39_04650	COG0477	Major facilitator Superfamily
EXW39_04655	COG3290	protein histidine kinase activity
EXW39_04660	COG4565	transcriptional regulatory protein
EXW39_04665	COG3181	Tripartite tricarboxylate transporter family receptor
EXW39_04705	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EXW39_04715	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EXW39_04740	COG1074	ATP-dependent DNA helicase activity
EXW39_04750	COG0210	DNA helicase
EXW39_04780	COG0305	Participates in initiation and elongation during chromosome replication
EXW39_04805	COG0477	Major facilitator Superfamily
EXW39_04855	COG1183	phosphatidylcholine synthase activity
EXW39_04880	COG1136	(ABC) transporter
EXW39_04885	COG0577	efflux transmembrane transporter activity
EXW39_04890	COG0745	RESPONSE REGULATOR receiver
EXW39_04895	COG2205	protein histidine kinase activity
EXW39_04950	COG2814	Major facilitator Superfamily
EXW39_04955	COG0640	Transcriptional regulator
EXW39_04980	COG2376	Dihydroxyacetone kinase
EXW39_05000	COG2376	Dihydroxyacetone kinase
EXW39_05010	COG1959	2 iron, 2 sulfur cluster binding
EXW39_05035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW39_05050	COG0457	Tetratricopeptide repeat
EXW39_05060	COG2720	vancomycin resistance protein
EXW39_05090	COG0596	Alpha beta hydrolase
EXW39_05115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW39_05120	COG1278	Cold shock
EXW39_05145	COG1136	(ABC) transporter
EXW39_05175	COG3237	CsbD-like
EXW39_05195	COG2172	sigma factor antagonist activity
EXW39_05200	COG1191	sigma factor activity
EXW39_05210	COG2208	phosphoserine phosphatase activity
EXW39_05215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW39_05220	COG0784	Response regulator, receiver
EXW39_05220	COG2205	protein histidine kinase activity
EXW39_05220	COG5002	protein histidine kinase activity
EXW39_05250	COG2807	transmembrane transport
EXW39_05265	COG4585	Histidine kinase
EXW39_05270	COG2197	response regulator
EXW39_05300	COG0420	3'-5' exonuclease activity
EXW39_05305	COG4717	serine-type aminopeptidase activity
EXW39_05310	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW39_05355	COG0346	lactoylglutathione lyase activity
EXW39_05360	COG0346	lactoylglutathione lyase activity
EXW39_05365	COG0457	Tetratricopeptide repeat
EXW39_05375	COG2267	carboxylic ester hydrolase activity
EXW39_05400	COG3620	sequence-specific DNA binding
EXW39_05405	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW39_05410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW39_05415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW39_05420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW39_05425	COG1695	Transcriptional regulator
EXW39_05435	COG1595	DNA-templated transcription, initiation
EXW39_05445	COG0772	Belongs to the SEDS family
EXW39_05450	COG3973	AAA domain
EXW39_05455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW39_05480	COG0537	adenosine 5'-monophosphoramidase activity
EXW39_05485	COG1131	(ABC) transporter
EXW39_05490	COG4473	ABC transporter
EXW39_05500	COG0247	lactate metabolic process
EXW39_05505	COG1139	Iron-sulfur cluster binding protein
EXW39_05510	COG1556	Lactate utilization protein
EXW39_05525	COG3402	PFAM membrane-flanked domain
EXW39_05530	COG3428	Bacterial PH domain
EXW39_05570	COG3402	PFAM membrane-flanked domain
EXW39_05575	COG3428	Bacterial PH domain
EXW39_05580	COG2329	Antibiotic biosynthesis monooxygenase
EXW39_05585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW39_05590	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW39_05595	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW39_05600	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW39_05620	COG1309	transcriptional regulator
EXW39_05625	COG1511	domain protein
EXW39_05660	COG1609	Transcriptional regulator
EXW39_05670	COG1234	tRNA 3'-trailer cleavage
EXW39_05675	COG0095	Lipoate-protein ligase
EXW39_05685	COG0318	PFAM AMP-dependent synthetase and ligase
EXW39_05700	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW39_05710	COG4208	sulfate ABC transporter
EXW39_05770	COG1408	metallophosphoesterase
EXW39_05775	COG1078	dGTPase activity
EXW39_05790	COG1595	DNA-templated transcription, initiation
EXW39_05800	COG2207	Transcriptional regulator
EXW39_05800	COG3708	Transcriptional regulator
EXW39_05805	COG2205	protein histidine kinase activity
EXW39_05810	COG0745	RESPONSE REGULATOR receiver
EXW39_05830	COG0501	Belongs to the peptidase M48B family
EXW39_05835	COG0840	transmembrane signaling receptor activity
EXW39_05840	COG0697	spore germination
EXW39_05855	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW39_05860	COG2224	Isocitrate lyase
EXW39_05870	COG1278	Cold shock
EXW39_05905	COG0398	Pfam SNARE associated Golgi protein
EXW39_05915	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW39_05920	COG1074	ATP-dependent DNA helicase activity
EXW39_05970	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW39_05995	COG0367	asparagine synthase
EXW39_06005	COG0753	catalase activity
EXW39_06010	COG0004	ammonium transporteR
EXW39_06020	COG1666	GTP binding
EXW39_06025	COG2996	Protein conserved in bacteria
EXW39_06040	COG1329	Transcriptional regulator
EXW39_06075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW39_06085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW39_06100	COG0561	phosphatase activity
EXW39_06120	COG2267	carboxylic ester hydrolase activity
EXW39_06135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW39_06140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW39_06145	COG5504	Zn-dependent protease
EXW39_06165	COG0180	Tryptophanyl-tRNA synthetase
EXW39_06180	COG4166	transmembrane transport
EXW39_06185	COG0601	transmembrane transport
EXW39_06190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW39_06195	COG0444	Belongs to the ABC transporter superfamily
EXW39_06200	COG4608	Belongs to the ABC transporter superfamily
EXW39_06205	COG0534	Mate efflux family protein
EXW39_06210	COG4166	transmembrane transport
EXW39_06225	COG0861	Integral membrane protein TerC family
EXW39_06230	COG4862	establishment of competence for transformation
EXW39_06235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW39_06245	COG1164	Oligoendopeptidase f
EXW39_06255	COG2346	COG2346, Truncated hemoglobins
EXW39_06260	COG4116	CYTH
EXW39_06270	COG2357	RelA SpoT domain protein
EXW39_06280	COG0564	pseudouridine synthase activity
EXW39_06290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW39_06295	COG0772	Belongs to the SEDS family
EXW39_06300	COG1216	Glycosyl transferase, family 2
EXW39_06320	COG0457	Tetratricopeptide repeat
EXW39_06320	COG0463	Glycosyl transferase, family 2
EXW39_06340	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW39_06355	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW39_06400	COG2153	protein acetylation
EXW39_06405	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW39_06410	COG2382	esterase
EXW39_06435	COG5492	domain, Protein
EXW39_06440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW39_06455	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW39_06455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW39_06460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW39_06465	COG0134	indole-3-glycerol-phosphate synthase activity
EXW39_06470	COG0135	phosphoribosylanthranilate isomerase activity
EXW39_06475	COG0133	tryptophan synthase activity
EXW39_06480	COG0159	tryptophan synthase activity
EXW39_06490	COG1620	l-lactate permease
EXW39_06495	COG5634	Uncharacterized conserved protein (DUF2278)
EXW39_06545	COG2226	methyltransferase
EXW39_06565	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW39_06570	COG0567	Dehydrogenase, E1 component
EXW39_06605	COG4152	abc transporter atp-binding protein
EXW39_06610	COG1668	transmembrane transport
EXW39_06625	COG0582	viral genome integration into host DNA
EXW39_06735	COG1686	Belongs to the peptidase S11 family
EXW39_06740	COG0681	Belongs to the peptidase S26 family
EXW39_06775	COG1012	belongs to the aldehyde dehydrogenase family
EXW39_06785	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW39_06790	COG1177	transmembrane transport
EXW39_06795	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW39_06805	COG2409	Drug exporters of the RND superfamily
EXW39_06815	COG0564	pseudouridine synthase activity
EXW39_06825	COG2340	Cysteine-rich secretory protein family
EXW39_06830	COG0247	lactate metabolic process
EXW39_06835	COG0277	FAD linked oxidase domain protein
EXW39_06840	COG3835	regulator
EXW39_06850	COG0745	RESPONSE REGULATOR receiver
EXW39_06855	COG5002	protein histidine kinase activity
EXW39_06860	COG2186	Transcriptional regulator
EXW39_06865	COG0247	lactate metabolic process
EXW39_06870	COG1139	Iron-sulfur cluster binding protein
EXW39_06875	COG1556	Lactate utilization protein
EXW39_06880	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW39_06890	COG2116	formate transmembrane transporter activity
EXW39_06895	COG0861	Integral membrane protein TerC family
EXW39_06900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW39_06910	COG2030	dehydratase
EXW39_06930	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_06935	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW39_06945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW39_06960	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW39_06965	COG3842	ATPase activity
EXW39_06975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW39_06980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW39_06990	COG1349	DNA-binding transcription factor activity
EXW39_07000	COG0235	Class ii aldolase
EXW39_07010	COG2861	carbohydrate metabolic process
EXW39_07020	COG3852	Histidine kinase
EXW39_07025	COG1846	Transcriptional regulator
EXW39_07035	COG2318	DinB family
EXW39_07040	COG5002	protein histidine kinase activity
EXW39_07045	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW39_07050	COG0720	synthase
EXW39_07060	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW39_07065	COG4873	Protein conserved in bacteria
EXW39_07075	COG0456	acetyltransferase
EXW39_07095	COG1780	Probably involved in ribonucleotide reductase function
EXW39_07110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW39_07115	COG0531	amino acid
EXW39_07120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW39_07135	COG2204	response regulator
EXW39_07140	COG1012	belongs to the aldehyde dehydrogenase family
EXW39_07150	COG1725	Transcriptional regulator
EXW39_07155	COG1131	(ABC) transporter
EXW39_07165	COG1131	(ABC) transporter
EXW39_07170	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW39_07175	COG1266	CAAX protease self-immunity
EXW39_07185	COG1522	sequence-specific DNA binding
EXW39_07195	COG1335	isochorismatase
EXW39_07205	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW39_07210	COG2070	2-Nitropropane dioxygenase
EXW39_07215	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW39_07220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW39_07225	COG1696	Membrane protein involved in D-alanine export
EXW39_07230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW39_07270	COG0534	Mate efflux family protein
EXW39_07290	COG1846	Transcriptional regulator
EXW39_07300	COG1301	dicarboxylic acid transport
EXW39_07305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW39_07315	COG3874	Sporulation protein YtfJ
EXW39_07335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW39_07340	COG0028	Belongs to the TPP enzyme family
EXW39_07345	COG0440	acetolactate synthase activity
EXW39_07355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW39_07365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW39_07375	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW39_07380	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW39_07390	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW39_07395	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW39_07400	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW39_07405	COG0107	imidazoleglycerol-phosphate synthase activity
EXW39_07415	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW39_07420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW39_07435	COG1183	phosphatidylcholine synthase activity
EXW39_07440	COG1368	sulfuric ester hydrolase activity
EXW39_07450	COG0019	diaminopimelate decarboxylase activity
EXW39_07460	COG0175	sulfate reduction
EXW39_07465	COG2046	Belongs to the sulfate adenylyltransferase family
EXW39_07470	COG0529	Catalyzes the synthesis of activated sulfate
EXW39_07475	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW39_07495	COG1648	precorrin-2 dehydrogenase activity
EXW39_07500	COG0733	neurotransmitter:sodium symporter activity
EXW39_07520	COG1757	Na H antiporter
EXW39_07540	COG4758	membrane
EXW39_07545	COG4585	Histidine kinase
EXW39_07550	COG2197	response regulator
EXW39_07560	COG1114	Component of the transport system for branched-chain amino acids
EXW39_07570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW39_07615	COG0730	response to heat
EXW39_07620	COG0306	phosphate transporter
EXW39_07625	COG1392	Phosphate transport regulator
EXW39_07630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW39_07645	COG3852	Histidine kinase
EXW39_07650	COG1801	Protein of unknown function DUF72
EXW39_07660	COG0582	viral genome integration into host DNA
EXW39_07665	COG5002	protein histidine kinase activity
EXW39_07680	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW39_07680	COG0392	lysyltransferase activity
EXW39_07695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW39_07700	COG1686	Belongs to the peptidase S11 family
EXW39_07705	COG2715	membrane protein required for spore maturation
EXW39_07710	COG0700	Nucleoside recognition
EXW39_07715	COG1187	pseudouridine synthase activity
EXW39_07725	COG1333	cytochrome c biogenesis protein
EXW39_07730	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW39_07735	COG0745	RESPONSE REGULATOR receiver
EXW39_07740	COG5002	protein histidine kinase activity
EXW39_07745	COG2096	Adenosyltransferase
EXW39_07750	COG4942	peptidase
EXW39_07760	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW39_07765	COG1141	Ferredoxin
EXW39_07775	COG4955	Helix-turn-helix domain
EXW39_07780	COG0514	ATP-dependent DNA helicase (RecQ)
EXW39_07785	COG1266	CAAX protease self-immunity
EXW39_07795	COG1408	metallophosphoesterase
EXW39_07810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW39_07830	COG0492	ferredoxin-NADP+ reductase activity
EXW39_07835	COG0252	asparaginase activity
EXW39_07840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW39_07850	COG1304	FMN binding
EXW39_07880	COG1160	GTP binding
EXW39_07885	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW39_07905	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW39_07915	COG0302	gtp cyclohydrolase
EXW39_07920	COG0142	geranyltranstransferase activity
EXW39_07925	COG2226	methyltransferase
EXW39_07930	COG0142	geranyltranstransferase activity
EXW39_07945	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW39_07955	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW39_07960	COG0457	Tetratricopeptide repeat
EXW39_07965	COG5582	Belongs to the UPF0302 family
EXW39_07980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW39_07995	COG4347	Protein of unknown function (DUF1405)
EXW39_08010	COG2738	Putative neutral zinc metallopeptidase
EXW39_08020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW39_08025	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW39_08030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW39_08035	COG1803	Methylglyoxal synthase
EXW39_08040	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW39_08045	COG0438	transferase activity, transferring glycosyl groups
EXW39_08050	COG0617	tRNA 3'-terminal CCA addition
EXW39_08060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW39_08065	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW39_08075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW39_08075	COG1199	ATP-dependent helicase activity
EXW39_08095	COG3935	DnaD domain protein
EXW39_08100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW39_08110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW39_08110	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW39_08115	COG3331	DNA recombination
EXW39_08150	COG4474	Belongs to the UPF0398 family
EXW39_08155	COG3599	regulation of cell shape
EXW39_08165	COG0116	Belongs to the methyltransferase superfamily
EXW39_08175	COG1199	ATP-dependent helicase activity
EXW39_08180	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW39_08190	COG0024	Methionine aminopeptidase
EXW39_08195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW39_08200	COG2233	PERMEase
EXW39_08205	COG2311	Membrane
EXW39_08210	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW39_08220	COG0456	acetyltransferase
EXW39_08230	COG2897	thiosulfate sulfurtransferase activity
EXW39_08270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW39_08290	COG3800	Transcriptional regulator
EXW39_08290	COG1396	sequence-specific DNA binding
EXW39_08305	COG3646	Phage regulatory protein
EXW39_08380	COG0582	viral genome integration into host DNA
EXW39_08400	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW39_08440	COG1802	Transcriptional regulator
EXW39_08440	COG4626	Terminase
EXW39_08450	COG0740	serine-type endopeptidase activity
EXW39_08515	COG4824	toxin secretion phage lysis holin
EXW39_08520	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW39_08520	COG3409	Peptidoglycan-binding domain 1 protein
EXW39_08520	COG1388	LysM domain
EXW39_08580	COG0454	-acetyltransferase
EXW39_08600	COG0328	RNA-DNA hybrid ribonuclease activity
EXW39_08635	COG3403	YqcI/YcgG family
EXW39_08640	COG1280	lysine exporter protein (LysE YggA)
EXW39_08655	COG3162	membrane
EXW39_08660	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW39_08665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW39_08675	COG0475	glutathione-regulated potassium exporter activity
EXW39_08680	COG4978	Transcriptional regulator
EXW39_08680	COG0789	Transcriptional regulator
EXW39_08690	COG2323	membrane
EXW39_08695	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW39_08750	COG1923	regulation of RNA biosynthetic process
EXW39_08760	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW39_08765	COG1360	Flagellar Motor Protein
EXW39_08770	COG2201	protein-glutamate methylesterase activity
EXW39_08775	COG0643	Histidine kinase
EXW39_08775	COG2198	Histidine kinase
EXW39_08780	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW39_08780	COG1776	CheC inhibitor of MCP methylation
EXW39_08795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW39_08815	COG1256	bacterial-type flagellum assembly
EXW39_08820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW39_08840	COG1815	bacterial-type flagellum-dependent cell motility
EXW39_08845	COG1558	bacterial-type flagellum-dependent cell motility
EXW39_08855	COG1766	The M ring may be actively involved in energy transduction
EXW39_08860	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW39_08870	COG1157	protein secretion by the type III secretion system
EXW39_08890	COG1749	Flagellar hook protein flgE
EXW39_08905	COG0784	Response regulator, receiver
EXW39_08905	COG0835	chemotaxis
EXW39_08930	COG0861	Integral membrane protein TerC family
EXW39_08940	COG3383	formate dehydrogenase (NAD+) activity
EXW39_08945	COG2427	Protein of unknown function (DUF1641)
EXW39_08950	COG5609	conserved protein (DUF2294)
EXW39_08955	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW39_08965	COG2116	formate transmembrane transporter activity
EXW39_08970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW39_08975	COG0303	'Molybdopterin
EXW39_08980	COG0314	molybdopterin synthase activity
EXW39_08985	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW39_08995	COG0489	protein tyrosine kinase activity
EXW39_09000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW39_09005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW39_09010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW39_09015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW39_09020	COG0741	lytic transglycosylase activity
EXW39_09030	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW39_09035	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW39_09035	COG1776	CheC inhibitor of MCP methylation
EXW39_09045	COG1338	Plays a role in the flagellum-specific transport system
EXW39_09050	COG1987	bacterial-type flagellum assembly
EXW39_09060	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW39_09065	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW39_09070	COG1419	protein localization to endoplasmic reticulum
EXW39_09075	COG4786	Flagellar basal body rod
EXW39_09080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW39_09110	COG0412	Dienelactone hydrolase
EXW39_09115	COG2329	Antibiotic biosynthesis monooxygenase
EXW39_09130	COG2814	Major facilitator Superfamily
EXW39_09140	COG0583	DNA-binding transcription factor activity
EXW39_09145	COG3842	ATPase activity
EXW39_09195	COG0406	alpha-ribazole phosphatase activity
EXW39_09225	COG0367	asparagine synthase
EXW39_09255	COG1802	Transcriptional regulator
EXW39_09260	COG0697	spore germination
EXW39_09265	COG0438	transferase activity, transferring glycosyl groups
EXW39_09265	COG1216	Glycosyl transferase, family 2
EXW39_09270	COG1757	Na H antiporter
EXW39_09300	COG0534	Mate efflux family protein
EXW39_09305	COG3340	Belongs to the peptidase S51 family
EXW39_09325	COG0785	Cytochrome C biogenesis protein
EXW39_09330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW39_09345	COG3048	D-serine ammonia-lyase activity
EXW39_09350	COG2733	membrane
EXW39_09390	COG1131	(ABC) transporter
EXW39_09405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW39_09410	COG0528	UMP kinase activity
EXW39_09420	COG1027	Aspartate ammonia-lyase
EXW39_09425	COG0281	malic enzyme
EXW39_09430	COG4191	Histidine kinase
EXW39_09435	COG0784	Response regulator, receiver
EXW39_09455	COG2502	aspartate--ammonia ligase
EXW39_09460	COG3620	sequence-specific DNA binding
EXW39_09500	COG2814	Major facilitator Superfamily
EXW39_09525	COG1695	Transcriptional regulator
EXW39_09540	COG0477	Major facilitator Superfamily
EXW39_09560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW39_09565	COG2223	nitrite transmembrane transporter activity
EXW39_09570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW39_09585	COG2244	polysaccharide biosynthetic process
EXW39_09590	COG0733	neurotransmitter:sodium symporter activity
EXW39_09600	COG5566	PFAM Mor transcription activator
EXW39_09605	COG2323	membrane
EXW39_09625	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW39_09635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW39_09640	COG0028	Belongs to the TPP enzyme family
EXW39_09655	COG0129	dihydroxy-acid dehydratase activity
EXW39_09660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW39_09685	COG2814	Major facilitator Superfamily
EXW39_09690	COG3384	dioxygenase
EXW39_09715	COG4166	transmembrane transport
EXW39_09745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW39_09765	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW39_09770	COG1054	Belongs to the UPF0176 family
EXW39_09780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW39_09785	COG0531	amino acid
EXW39_09820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW39_09835	COG4257	antibiotic catabolic process
EXW39_09840	COG2390	Transcriptional regulator
EXW39_09850	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW39_09855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW39_09860	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW39_09875	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW39_09905	COG0006	proline dipeptidase activity
EXW39_09910	COG2132	Multicopper oxidase
EXW39_09925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW39_09935	COG0583	DNA-binding transcription factor activity
EXW39_09955	COG1114	Component of the transport system for branched-chain amino acids
EXW39_09965	COG1834	amidinotransferase
EXW39_09975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW39_10020	COG2372	response to copper ion
EXW39_10020	COG1276	copper resistance
EXW39_10025	COG4549	nuclear export factor GLE1
EXW39_10035	COG0697	spore germination
EXW39_10040	COG0583	DNA-binding transcription factor activity
EXW39_10045	COG1959	2 iron, 2 sulfur cluster binding
EXW39_10050	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW39_10055	COG0778	Nitroreductase
EXW39_10070	COG0628	permease
EXW39_10085	COG1231	oxidoreductase activity
EXW39_10090	COG0523	cobalamin synthesis protein
EXW39_10100	COG0411	ABC transporter
EXW39_10120	COG0583	DNA-binding transcription factor activity
EXW39_10130	COG1942	4-Oxalocrotonate Tautomerase
EXW39_10145	COG0346	lactoylglutathione lyase activity
EXW39_10155	COG1271	oxidase subunit
EXW39_10160	COG1294	oxidase, subunit
EXW39_10165	COG4988	ABC transporter
EXW39_10170	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW39_10200	COG1686	Belongs to the peptidase S11 family
EXW39_10215	COG0791	NLP P60 protein
EXW39_10215	COG1388	LysM domain
EXW39_10225	COG1132	(ABC) transporter
EXW39_10230	COG0745	RESPONSE REGULATOR receiver
EXW39_10235	COG5002	protein histidine kinase activity
EXW39_10240	COG0300	oxidoreductase activity
EXW39_10245	COG4122	O-methyltransferase activity
EXW39_10275	COG0460	homoserine dehydrogenase
EXW39_10285	COG0083	homoserine kinase activity
EXW39_10300	COG1316	TRANSCRIPTIONal
EXW39_10310	COG0745	RESPONSE REGULATOR receiver
EXW39_10315	COG5002	protein histidine kinase activity
EXW39_10340	COG1285	pathogenesis
EXW39_10345	COG1247	-acetyltransferase
EXW39_10365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW39_10375	COG1082	Xylose isomerase domain protein TIM barrel
EXW39_10385	COG2814	Major facilitator Superfamily
EXW39_10390	COG1279	arginine transmembrane transporter activity
EXW39_10395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW39_10405	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW39_10435	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW39_10440	COG0577	efflux transmembrane transporter activity
EXW39_10445	COG2002	toxin-antitoxin pair type II binding
EXW39_10450	COG1404	Belongs to the peptidase S8 family
EXW39_10455	COG0640	Transcriptional regulator
EXW39_10460	COG0667	Aldo Keto reductase
EXW39_10490	COG0840	transmembrane signaling receptor activity
EXW39_10505	COG3949	Membrane
EXW39_10510	COG0783	Belongs to the Dps family
EXW39_10525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW39_10535	COG1231	oxidoreductase activity
EXW39_10540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW39_10545	COG4989	oxidoreductase activity
EXW39_10550	COG0523	cobalamin synthesis protein
EXW39_10565	COG0456	acetyltransferase
EXW39_10570	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW39_10585	COG1902	pentaerythritol trinitrate reductase activity
EXW39_10590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW39_10600	COG4166	transmembrane transport
EXW39_10605	COG0346	lactoylglutathione lyase activity
EXW39_10615	COG0406	alpha-ribazole phosphatase activity
EXW39_10625	COG5337	Spore coat protein CotH
EXW39_10630	COG1051	belongs to the nudix hydrolase family
EXW39_10635	COG0586	Pfam SNARE associated Golgi protein
EXW39_10640	COG2244	polysaccharide biosynthetic process
EXW39_10650	COG0701	Predicted permease
EXW39_10655	COG3689	TIGRFAM TIGR03943 family protein
EXW39_10660	COG1607	acyl-coa hydrolase
EXW39_10670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW39_10690	COG0702	epimerase
EXW39_10695	COG2839	Protein conserved in bacteria
EXW39_10700	COG1253	flavin adenine dinucleotide binding
EXW39_10715	COG1114	Component of the transport system for branched-chain amino acids
EXW39_10720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW39_10740	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW39_10755	COG1876	peptidase activity
EXW39_10760	COG0494	nUDIX hydrolase
EXW39_10785	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW39_10795	COG0561	phosphatase activity
EXW39_10805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW39_10810	COG4106	trans-aconitate 2-methyltransferase activity
EXW39_10825	COG1819	glycosyl
EXW39_10830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW39_10835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW39_10860	COG0456	acetyltransferase
EXW39_10880	COG3874	Sporulation protein YtfJ
EXW39_10905	COG2226	methyltransferase
EXW39_10945	COG0604	alcohol dehydrogenase
EXW39_10950	COG1595	DNA-templated transcription, initiation
EXW39_10970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW39_10970	COG0426	domain, Protein
EXW39_10980	COG0386	Belongs to the glutathione peroxidase family
EXW39_10985	COG1305	Transglutaminase-like
EXW39_10990	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW39_10995	COG0714	Associated with various cellular activities
EXW39_11000	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW39_11005	COG1140	nitrate reductase beta subunit
EXW39_11010	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW39_11015	COG2181	nitrate reductase activity
EXW39_11020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW39_11025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW39_11030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW39_11035	COG0303	'Molybdopterin
EXW39_11040	COG0314	molybdopterin synthase activity
EXW39_11050	COG2223	nitrite transmembrane transporter activity
EXW39_11070	COG1648	precorrin-2 dehydrogenase activity
EXW39_11080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW39_11080	COG1587	Uroporphyrinogen-III synthase
EXW39_11085	COG2146	nitrite reductase [NAD(P)H] activity
EXW39_11090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW39_11095	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW39_11130	COG2359	stage V sporulation protein S
EXW39_11175	COG0582	viral genome integration into host DNA
EXW39_11220	COG1418	mRNA catabolic process
EXW39_11225	COG0488	(ABC) transporter
EXW39_11245	COG1413	lyase activity
EXW39_11260	COG2521	methyltransferase
EXW39_11260	COG2136	Putative SAM-dependent methyltransferase
EXW39_11265	COG0018	arginyl-trna synthetase
EXW39_11315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW39_11325	COG0017	Asparaginyl-tRNA synthetase
EXW39_11345	COG1674	ftsk spoiiie
EXW39_11410	COG0733	neurotransmitter:sodium symporter activity
EXW39_11440	COG2610	gluconate transmembrane transporter activity
EXW39_11450	COG1794	racemase activity, acting on amino acids and derivatives
EXW39_11460	COG0456	acetyltransferase
EXW39_11465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW39_11470	COG1131	(ABC) transporter
EXW39_11475	COG4473	ABC transporter
EXW39_11485	COG0546	phosphoglycolate phosphatase activity
EXW39_11545	COG0768	penicillin binding
EXW39_11560	COG1272	protein, Hemolysin III
EXW39_11570	COG0805	protein transport
EXW39_11580	COG1307	EDD domain protein, DegV family
EXW39_11585	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW39_11590	COG1999	signal sequence binding
EXW39_11595	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW39_11600	COG0367	asparagine synthase
EXW39_11615	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW39_11620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW39_11625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW39_11645	COG1335	isochorismatase
EXW39_11655	COG0668	transmembrane transport
EXW39_11660	COG4585	Histidine kinase
EXW39_11660	COG2203	Gaf domain
EXW39_11665	COG2197	response regulator
EXW39_11670	COG1737	Transcriptional regulator
EXW39_11675	COG1064	alcohol dehydrogenase
EXW39_11690	COG1070	Carbohydrate kinase
EXW39_11700	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW39_11720	COG0517	IMP dehydrogenase activity
EXW39_11720	COG1125	glycine betaine transport
EXW39_11725	COG1174	glycine betaine transport
EXW39_11760	COG1253	flavin adenine dinucleotide binding
EXW39_11765	COG1012	belongs to the aldehyde dehydrogenase family
EXW39_11770	COG5506	Protein of unknown function (DUF1694)
EXW39_11785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW39_11790	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW39_11795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW39_11800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW39_11805	COG0456	acetyltransferase
EXW39_11810	COG3829	transcription factor binding
EXW39_11815	COG1509	lysine 2,3-aminomutase activity
EXW39_11825	COG4479	Belongs to the UPF0346 family
EXW39_11850	COG0515	serine threonine protein kinase
EXW39_11850	COG3064	Membrane
EXW39_11850	COG4991	sh3 domain protein
EXW39_11860	COG0671	phosphoesterase, PA-phosphatase related
EXW39_11865	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW39_11870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW39_11930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW39_11955	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_11975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW39_11975	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW39_11985	COG2814	Major facilitator Superfamily
EXW39_11995	COG0372	Belongs to the citrate synthase family
EXW39_12000	COG2079	MmgE PrpD family protein
EXW39_12005	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW39_12010	COG1960	acyl-CoA dehydrogenase activity
EXW39_12015	COG2084	Dehydrogenase
EXW39_12020	COG1012	belongs to the aldehyde dehydrogenase family
EXW39_12025	COG1280	lysine exporter protein (LysE YggA)
EXW39_12030	COG1024	Enoyl-CoA hydratase
EXW39_12045	COG0420	3'-5' exonuclease activity
EXW39_12055	COG3397	chitin binding
EXW39_12060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW39_12075	COG2223	nitrite transmembrane transporter activity
EXW39_12085	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_12090	COG1169	isochorismate synthase
EXW39_12095	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW39_12100	COG1535	isochorismatase
EXW39_12100	COG3433	isochorismatase activity
EXW39_12105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW39_12110	COG3251	PFAM MbtH domain protein
EXW39_12115	COG2814	Major facilitator Superfamily
EXW39_12130	COG0776	regulation of translation
EXW39_12140	COG2318	DinB family
EXW39_12145	COG1115	amino acid carrier protein
EXW39_12160	COG2329	Antibiotic biosynthesis monooxygenase
EXW39_12175	COG1187	pseudouridine synthase activity
EXW39_12180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW39_12185	COG3655	Transcriptional regulator
EXW39_12195	COG1136	(ABC) transporter
EXW39_12205	COG0596	Alpha beta hydrolase
EXW39_12220	COG0028	Belongs to the TPP enzyme family
EXW39_12235	COG1253	flavin adenine dinucleotide binding
EXW39_12265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW39_12285	COG1846	Transcriptional regulator
EXW39_12300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW39_12305	COG1309	transcriptional regulator
EXW39_12315	COG0697	spore germination
EXW39_12320	COG0531	amino acid
EXW39_12340	COG1247	-acetyltransferase
EXW39_12370	COG0596	Alpha beta hydrolase
EXW39_12375	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW39_12385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW39_12415	COG0583	DNA-binding transcription factor activity
EXW39_12420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW39_12435	COG0583	DNA-binding transcription factor activity
EXW39_12440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW39_12445	COG2258	MOSC domain
EXW39_12460	COG1132	(ABC) transporter
EXW39_12465	COG1132	(ABC) transporter
EXW39_12480	COG0189	ligase activity
EXW39_12500	COG1396	sequence-specific DNA binding
EXW39_12530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW39_12540	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW39_12545	COG1595	DNA-templated transcription, initiation
EXW39_12565	COG1649	PFAM Uncharacterised BCR, COG1649
EXW39_12585	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW39_12590	COG2971	BadF BadG BcrA BcrD
EXW39_12600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW39_12655	COG1309	transcriptional regulator
EXW39_12670	COG1136	(ABC) transporter
EXW39_12670	COG0577	efflux transmembrane transporter activity
EXW39_12685	COG0693	protein deglycase activity
EXW39_12695	COG0588	phosphoglycerate mutase activity
EXW39_12715	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW39_12730	COG0110	maltose O-acetyltransferase activity
EXW39_12745	COG1136	(ABC) transporter
EXW39_12780	COG1686	Belongs to the peptidase S11 family
EXW39_12805	COG0768	penicillin binding
EXW39_12810	COG0745	RESPONSE REGULATOR receiver
EXW39_12815	COG2205	protein histidine kinase activity
EXW39_12820	COG1136	(ABC) transporter
EXW39_12825	COG0577	efflux transmembrane transporter activity
EXW39_12835	COG1595	DNA-templated transcription, initiation
EXW39_12845	COG0768	penicillin binding
EXW39_12850	COG0768	penicillin binding
EXW39_12885	COG1404	Belongs to the peptidase S8 family
EXW39_12895	COG1252	NADH dehydrogenase
EXW39_12900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW39_12900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW39_12915	COG0697	spore germination
EXW39_12945	COG3397	chitin binding
EXW39_12950	COG0823	Involved in the tonB-independent uptake of proteins
EXW39_12960	COG1408	metallophosphoesterase
EXW39_12970	COG1131	(ABC) transporter
EXW39_12980	COG1309	transcriptional regulator
EXW39_12990	COG1960	acyl-CoA dehydrogenase activity
EXW39_12995	COG0439	Biotin carboxylase
EXW39_13000	COG0511	ligase activity, forming carbon-carbon bonds
EXW39_13005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW39_13010	COG1024	Enoyl-CoA hydratase
EXW39_13015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW39_13020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW39_13065	COG2318	DinB family
EXW39_13070	COG1686	Belongs to the peptidase S11 family
EXW39_13095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW39_13120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW39_13145	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_13150	COG1733	regulation of RNA biosynthetic process
EXW39_13190	COG0697	spore germination
EXW39_13195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW39_13230	COG2323	membrane
EXW39_13245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW39_13250	COG0697	spore germination
EXW39_13255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW39_13260	COG0201	protein transport
EXW39_13270	COG0737	Belongs to the 5'-nucleotidase family
EXW39_13275	COG3227	Zinc metalloprotease (Elastase)
EXW39_13280	COG1523	belongs to the glycosyl hydrolase 13 family
EXW39_13295	COG0076	glutamate decarboxylase activity
EXW39_13300	COG0657	acetylesterase activity
EXW39_13310	COG1073	alpha beta
EXW39_13320	COG0577	efflux transmembrane transporter activity
EXW39_13325	COG1136	(ABC) transporter
EXW39_13340	COG5002	protein histidine kinase activity
EXW39_13345	COG0745	RESPONSE REGULATOR receiver
EXW39_13350	COG1011	Hydrolase
EXW39_13375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW39_13380	COG1183	phosphatidylcholine synthase activity
EXW39_13395	COG3961	Belongs to the TPP enzyme family
EXW39_13415	COG0322	excinuclease ABC activity
EXW39_13440	COG2318	DinB family
EXW39_13455	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW39_13480	COG3878	Protein conserved in bacteria
EXW39_13505	COG1051	belongs to the nudix hydrolase family
EXW39_13510	COG0592	DNA-directed DNA polymerase activity
EXW39_13515	COG2816	NAD+ diphosphatase activity
EXW39_13525	COG2223	nitrite transmembrane transporter activity
EXW39_13530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW39_13540	COG0494	nUDIX hydrolase
EXW39_13560	COG0697	spore germination
EXW39_13565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW39_13580	COG0584	glycerophosphoryl diester phosphodiesterase
EXW39_13595	COG1733	regulation of RNA biosynthetic process
EXW39_13605	COG2814	Major facilitator Superfamily
EXW39_13650	COG0768	penicillin binding
EXW39_13655	COG0671	phosphoesterase, PA-phosphatase related
EXW39_13660	COG0604	alcohol dehydrogenase
EXW39_13665	COG5002	protein histidine kinase activity
EXW39_13670	COG0745	RESPONSE REGULATOR receiver
EXW39_13680	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW39_13690	COG2205	protein histidine kinase activity
EXW39_13705	COG1122	ATPase activity
EXW39_13710	COG4720	Psort location CytoplasmicMembrane, score
EXW39_13715	COG1794	racemase activity, acting on amino acids and derivatives
EXW39_13720	COG1819	glycosyl
EXW39_13730	COG0768	penicillin binding
EXW39_13735	COG5002	protein histidine kinase activity
EXW39_13740	COG0561	phosphatase activity
EXW39_13790	COG2124	cytochrome p450
EXW39_13840	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW39_13850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW39_13855	COG0460	homoserine dehydrogenase
EXW39_13875	COG0577	efflux transmembrane transporter activity
EXW39_13880	COG1136	(ABC) transporter
EXW39_13895	COG0488	(ABC) transporter
EXW39_13900	COG0667	Aldo Keto reductase
EXW39_13905	COG0583	DNA-binding transcription factor activity
EXW39_13915	COG2205	protein histidine kinase activity
EXW39_13920	COG0745	RESPONSE REGULATOR receiver
EXW39_13930	COG3773	Cell wall hydrolase
EXW39_13935	COG0604	alcohol dehydrogenase
EXW39_13965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW39_13980	COG2959	enzyme of heme biosynthesis
EXW39_14010	COG3483	tryptophan 2,3-dioxygenase activity
EXW39_14015	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW39_14020	COG3844	kynureninase activity
EXW39_14025	COG1309	transcriptional regulator
EXW39_14040	COG3284	Transcriptional regulator
EXW39_14055	COG1349	DNA-binding transcription factor activity
EXW39_14075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW39_14080	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW39_14085	COG0022	dehydrogenase e1 component
EXW39_14090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW39_14100	COG2223	nitrite transmembrane transporter activity
EXW39_14110	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_14115	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW39_14115	COG0456	acetyltransferase
EXW39_14150	COG4176	ABC-type proline glycine betaine transport system permease component
EXW39_14155	COG0517	IMP dehydrogenase activity
EXW39_14155	COG4175	Glycine betaine
EXW39_14180	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW39_14185	COG2153	protein acetylation
EXW39_14190	COG3397	chitin binding
EXW39_14200	COG1819	glycosyl
EXW39_14215	COG2205	protein histidine kinase activity
EXW39_14220	COG2315	Protein conserved in bacteria
EXW39_14270	COG3973	AAA domain
EXW39_14280	COG2105	PFAM AIG2 family protein
EXW39_14285	COG0514	ATP-dependent DNA helicase (RecQ)
EXW39_14305	COG4637	Psort location Cytoplasmic, score
EXW39_14320	COG1227	inorganic diphosphatase activity
EXW39_14325	COG3397	chitin binding
EXW39_14330	COG2318	DinB family
EXW39_14350	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW39_14355	COG1115	amino acid carrier protein
EXW39_14360	COG1012	belongs to the aldehyde dehydrogenase family
EXW39_14365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW39_14375	COG3938	Belongs to the proline racemase family
EXW39_14380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW39_14425	COG0586	Pfam SNARE associated Golgi protein
EXW39_14440	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW39_14445	COG4166	transmembrane transport
EXW39_14455	COG4948	Mandelate Racemase Muconate Lactonizing
EXW39_14475	COG0667	Aldo Keto reductase
EXW39_14520	COG2936	dipeptidyl-peptidase activity
EXW39_14530	COG0745	RESPONSE REGULATOR receiver
EXW39_14550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW39_14555	COG1164	Oligoendopeptidase f
EXW39_14565	COG1307	EDD domain protein, DegV family
EXW39_14595	COG1335	isochorismatase
EXW39_14610	COG2814	Major facilitator Superfamily
EXW39_14620	COG1664	Polymer-forming cytoskeletal
EXW39_14625	COG0789	Transcriptional regulator
EXW39_14630	COG4533	DNA binding
EXW39_14635	COG0477	Major facilitator Superfamily
EXW39_14635	COG2814	Major facilitator Superfamily
EXW39_14655	COG2261	transglycosylase associated protein
EXW39_14670	COG2226	methyltransferase
EXW39_14705	COG0436	Aminotransferase
EXW39_14710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW39_14735	COG1131	(ABC) transporter
EXW39_14740	COG2188	Transcriptional regulator
EXW39_14785	COG0628	permease
EXW39_14815	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW39_14825	COG0697	spore germination
EXW39_14875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW39_14885	COG2814	Major facilitator Superfamily
EXW39_14890	COG1368	sulfuric ester hydrolase activity
EXW39_14905	COG0488	(ABC) transporter
EXW39_14910	COG1033	growth of symbiont in host cell
EXW39_14910	COG2409	Drug exporters of the RND superfamily
EXW39_14915	COG1309	transcriptional regulator
EXW39_14940	COG0287	Prephenate dehydrogenase
EXW39_14955	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW39_14955	COG1605	Chorismate mutase
EXW39_14995	COG1388	LysM domain
EXW39_14995	COG3584	3D domain protein
EXW39_15005	COG0346	lactoylglutathione lyase activity
EXW39_15015	COG0431	NADPH-dependent FMN reductase
EXW39_15045	COG0579	oxidoreductase
EXW39_15050	COG1879	ABC-type sugar transport system periplasmic component
EXW39_15065	COG1129	ABC transporter
EXW39_15070	COG2390	Transcriptional regulator
EXW39_15105	COG0346	lactoylglutathione lyase activity
EXW39_15110	COG2329	Antibiotic biosynthesis monooxygenase
EXW39_15130	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW39_15135	COG2207	Transcriptional regulator
EXW39_15140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW39_15145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW39_15150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW39_15155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW39_15160	COG3239	Fatty acid desaturase
EXW39_15180	COG3655	Transcriptional regulator
EXW39_15225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW39_15230	COG0346	lactoylglutathione lyase activity
EXW39_15255	COG0714	Associated with various cellular activities
EXW39_15275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW39_15280	COG0753	catalase activity
EXW39_15290	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW39_15315	COG0714	Associated with various cellular activities
EXW39_15325	COG0778	Nitroreductase
EXW39_15330	COG1846	Transcriptional regulator
EXW39_15350	COG1051	belongs to the nudix hydrolase family
EXW39_15355	COG3831	ATPase activity
EXW39_15355	COG4884	unkown
EXW39_15380	COG2207	Transcriptional regulator
EXW39_15385	COG0456	acetyltransferase
EXW39_15400	COG0697	spore germination
EXW39_15405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW39_15410	COG1671	Belongs to the UPF0178 family
EXW39_15430	COG0456	acetyltransferase
EXW39_15430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW39_15455	COG0730	response to heat
EXW39_15465	COG0833	amino acid
EXW39_15510	COG0768	penicillin binding
EXW39_15520	COG3104	oligopeptide transport
EXW39_15525	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW39_15540	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW39_15545	COG1984	allophanate hydrolase subunit 2
EXW39_15550	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW39_15555	COG1414	Transcriptional regulator
EXW39_15575	COG1960	acyl-CoA dehydrogenase activity
EXW39_15600	COG0640	Transcriptional regulator
EXW39_15610	COG3314	Sporulation integral membrane protein YlbJ
EXW39_15630	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW39_15635	COG0577	efflux transmembrane transporter activity
EXW39_15640	COG0577	efflux transmembrane transporter activity
EXW39_15645	COG1136	(ABC) transporter
EXW39_15675	COG0574	Belongs to the PEP-utilizing enzyme family
EXW39_15675	COG3848	Pyruvate phosphate dikinase
EXW39_15690	COG1131	(ABC) transporter
EXW39_15695	COG1131	(ABC) transporter
EXW39_15700	COG1309	transcriptional regulator
EXW39_15705	COG2357	RelA SpoT domain protein
EXW39_15735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW39_15760	COG1131	(ABC) transporter
EXW39_15770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW39_15785	COG1073	alpha beta
EXW39_15835	COG5002	protein histidine kinase activity
EXW39_15840	COG0745	RESPONSE REGULATOR receiver
EXW39_15850	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW39_15880	COG0798	PFAM Bile acid sodium symporter
EXW39_15885	COG0346	lactoylglutathione lyase activity
EXW39_15890	COG0640	Transcriptional regulator
EXW39_15915	COG3320	Male sterility
EXW39_15915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW39_15920	COG1309	transcriptional regulator
EXW39_15925	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_15930	COG1522	sequence-specific DNA binding
EXW39_15945	COG0346	lactoylglutathione lyase activity
EXW39_15980	COG2814	Major facilitator Superfamily
EXW39_16010	COG0745	RESPONSE REGULATOR receiver
EXW39_16015	COG5002	protein histidine kinase activity
EXW39_16015	COG3850	Histidine kinase
EXW39_16045	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW39_16065	COG2309	aminopeptidase activity
EXW39_16070	COG2226	methyltransferase
EXW39_16090	COG1690	Belongs to the RtcB family
EXW39_16105	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW39_16125	COG1136	(ABC) transporter
EXW39_16130	COG0577	efflux transmembrane transporter activity
EXW39_16150	COG3850	Histidine kinase
EXW39_16150	COG5002	protein histidine kinase activity
EXW39_16165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW39_16195	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW39_16215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW39_16245	COG0814	amino acid
EXW39_16250	COG1760	l-serine dehydratase
EXW39_16255	COG1760	l-serine dehydratase
EXW39_16265	COG5002	protein histidine kinase activity
EXW39_16270	COG0745	RESPONSE REGULATOR receiver
EXW39_16280	COG5002	protein histidine kinase activity
EXW39_16295	COG0814	amino acid
EXW39_16300	COG0697	spore germination
EXW39_16325	COG4977	sequence-specific DNA binding
EXW39_16380	COG2814	Major facilitator Superfamily
EXW39_16400	COG1876	peptidase activity
EXW39_16405	COG2843	Capsule synthesis protein
EXW39_16420	COG0477	Major facilitator Superfamily
EXW39_16435	COG1846	Transcriptional regulator
EXW39_16440	COG2814	Major facilitator Superfamily
EXW39_16455	COG0789	Transcriptional regulator
EXW39_16490	COG1476	TRANSCRIPTIONal
EXW39_16505	COG1288	antiporter activity
EXW39_16510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW39_16555	COG3718	enzyme involved in inositol metabolism
EXW39_16585	COG0673	inositol 2-dehydrogenase activity
EXW39_16590	COG2814	Major facilitator Superfamily
EXW39_16600	COG1609	Transcriptional regulator
EXW39_16680	COG0494	nUDIX hydrolase
EXW39_16720	COG2002	toxin-antitoxin pair type II binding
EXW39_16745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW39_16755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW39_16805	COG4187	Peptidase family M20/M25/M40
EXW39_16810	COG1414	Transcriptional regulator
EXW39_16820	COG0833	amino acid
EXW39_16835	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW39_16840	COG2031	fatty acid transporter
EXW39_16850	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW39_16915	COG1288	antiporter activity
EXW39_16920	COG2356	endonuclease I
EXW39_16925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW39_16940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW39_16960	COG1785	Belongs to the alkaline phosphatase family
EXW39_16965	COG0778	Nitroreductase
EXW39_16970	COG1733	regulation of RNA biosynthetic process
EXW39_16985	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_16995	COG1131	(ABC) transporter
EXW39_17025	COG1595	DNA-templated transcription, initiation
EXW39_17040	COG1011	Hydrolase
EXW39_17045	COG2365	Tyrosine phosphatase family
EXW39_17075	COG0628	permease
EXW39_17080	COG2261	transglycosylase associated protein
EXW39_17100	COG0500	methyltransferase
EXW39_17125	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW39_17135	COG1253	flavin adenine dinucleotide binding
EXW39_17140	COG0789	Transcriptional regulator
EXW39_17145	COG0697	spore germination
EXW39_17155	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW39_17160	COG3813	Protein conserved in bacteria
EXW39_17165	COG4702	Belongs to the UPF0303 family
EXW39_17175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW39_17195	COG0384	phenazine biosynthesis protein PhzF
EXW39_17205	COG0318	PFAM AMP-dependent synthetase and ligase
EXW39_17210	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW39_17215	COG1733	regulation of RNA biosynthetic process
EXW39_17230	COG1191	sigma factor activity
EXW39_17255	COG1876	peptidase activity
EXW39_17280	COG0741	lytic transglycosylase activity
EXW39_17315	COG0745	RESPONSE REGULATOR receiver
EXW39_17335	COG0657	acetylesterase activity
EXW39_17345	COG2814	Major facilitator Superfamily
EXW39_17350	COG1309	transcriptional regulator
EXW39_17380	COG0814	amino acid
EXW39_17405	COG1151	hydroxylamine reductase activity
EXW39_17435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW39_17445	COG2072	flavoprotein involved in K transport
EXW39_17485	COG0604	alcohol dehydrogenase
EXW39_17490	COG1113	amino acid transport
EXW39_17500	COG2814	Major facilitator Superfamily
EXW39_17515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW39_17520	COG1012	belongs to the aldehyde dehydrogenase family
EXW39_17530	COG0534	Mate efflux family protein
EXW39_17535	COG1012	belongs to the aldehyde dehydrogenase family
EXW39_17540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW39_17555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW39_17560	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW39_17580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW39_17585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW39_17590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW39_17595	COG3739	integral membrane protein
EXW39_17615	COG0583	DNA-binding transcription factor activity
EXW39_17640	COG1193	negative regulation of DNA recombination
EXW39_17660	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW39_17665	COG1164	Oligoendopeptidase f
EXW39_17680	COG0789	Transcriptional regulator
EXW39_17680	COG4978	Transcriptional regulator
EXW39_17690	COG3781	membrane
EXW39_17705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW39_17770	COG0640	Transcriptional regulator
EXW39_17775	COG0604	alcohol dehydrogenase
EXW39_17780	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW39_17785	COG0457	Tetratricopeptide repeat
EXW39_17795	COG2808	Putative FMN-binding domain
EXW39_17800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW39_17810	COG0277	FAD linked oxidase domain protein
EXW39_17825	COG0825	malonyl-CoA metabolic process
EXW39_17860	COG1285	pathogenesis
EXW39_17870	COG2514	catechol 2,3-dioxygenase activity
EXW39_17875	COG2720	vancomycin resistance protein
EXW39_17900	COG1278	Cold shock
EXW39_17910	COG0716	FMN binding
EXW39_17920	COG0494	nUDIX hydrolase
EXW39_17940	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_17950	COG0165	Argininosuccinate lyase
EXW39_17965	COG4145	pantothenate transmembrane transporter activity
EXW39_17975	COG1012	belongs to the aldehyde dehydrogenase family
EXW39_17980	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_17990	COG1657	PFAM Prenyltransferase squalene oxidase
EXW39_17995	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW39_18000	COG2962	Rard protein
EXW39_18005	COG3326	Membrane
EXW39_18035	COG2226	methyltransferase
EXW39_18040	COG4166	transmembrane transport
EXW39_18045	COG4166	transmembrane transport
EXW39_18050	COG4166	transmembrane transport
EXW39_18060	COG1131	(ABC) transporter
EXW39_18080	COG0673	inositol 2-dehydrogenase activity
EXW39_18090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW39_18095	COG0187	DNA topoisomerase II activity
EXW39_18100	COG1832	CoA-binding protein
EXW39_18105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW39_18110	COG0745	RESPONSE REGULATOR receiver
EXW39_18120	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW39_18120	COG1328	CTP reductase activity
EXW39_18130	COG4841	protein insertion into membrane
EXW39_18135	COG0824	Thioesterase
EXW39_18160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW39_18180	COG1132	(ABC) transporter
EXW39_18185	COG1266	CAAX protease self-immunity
EXW39_18190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW39_18220	COG2211	Major facilitator Superfamily
EXW39_18230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW39_18245	COG0183	Belongs to the thiolase family
EXW39_18250	COG0318	PFAM AMP-dependent synthetase and ligase
EXW39_18255	COG1268	BioY protein
EXW39_18260	COG0318	PFAM AMP-dependent synthetase and ligase
EXW39_18275	COG1396	sequence-specific DNA binding
EXW39_18320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW39_18335	COG5002	protein histidine kinase activity
EXW39_18345	COG0400	carboxylic ester hydrolase activity
EXW39_18350	COG0346	lactoylglutathione lyase activity
EXW39_18355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW39_18360	COG0069	glutamate synthase activity
EXW39_18365	COG1902	pentaerythritol trinitrate reductase activity
EXW39_18375	COG1329	Transcriptional regulator
EXW39_18380	COG0010	Belongs to the arginase family
EXW39_18390	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW39_18395	COG2986	histidine ammonia-lyase
EXW39_18405	COG2226	methyltransferase
EXW39_18435	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW39_18440	COG0785	Cytochrome C biogenesis protein
EXW39_18455	COG1473	amidohydrolase
EXW39_18460	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW39_18465	COG1131	(ABC) transporter
EXW39_18475	COG0583	DNA-binding transcription factor activity
EXW39_18485	COG1346	cytolysis
EXW39_18490	COG1051	belongs to the nudix hydrolase family
EXW39_18500	COG0730	response to heat
EXW39_18510	COG3409	Peptidoglycan-binding domain 1 protein
EXW39_18510	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW39_18530	COG1132	(ABC) transporter
EXW39_18535	COG1132	(ABC) transporter
EXW39_18540	COG3763	UPF0154 protein
EXW39_18560	COG3639	organic phosphonate transmembrane transporter activity
EXW39_18570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW39_18575	COG0737	Belongs to the 5'-nucleotidase family
EXW39_18585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW39_18590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW39_18605	COG1695	Transcriptional regulator
EXW39_18610	COG1132	(ABC) transporter
EXW39_18645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW39_18655	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW39_18660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW39_18665	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW39_18665	COG3420	alginic acid biosynthetic process
EXW39_18690	COG0438	transferase activity, transferring glycosyl groups
EXW39_18700	COG0463	Glycosyl transferase, family 2
EXW39_18700	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW39_18705	COG0438	transferase activity, transferring glycosyl groups
EXW39_18710	COG0438	transferase activity, transferring glycosyl groups
EXW39_18715	COG1086	Polysaccharide biosynthesis protein
EXW39_18720	COG0489	protein tyrosine kinase activity
EXW39_18725	COG3944	biosynthesis protein
EXW39_18730	COG0174	glutamine synthetase
EXW39_18735	COG0789	Transcriptional regulator
EXW39_18740	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW39_18745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW39_18750	COG2860	membrane
EXW39_18755	COG0464	growth
EXW39_18775	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW39_18785	COG3584	3D domain protein
EXW39_18785	COG1388	LysM domain
EXW39_18790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW39_18790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW39_18790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW39_18795	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW39_18800	COG1349	DNA-binding transcription factor activity
EXW39_18805	COG1979	alcohol dehydrogenase
EXW39_18810	COG2322	membrane
EXW39_18820	COG1113	amino acid transport
EXW39_18835	COG1473	amidohydrolase
EXW39_18840	COG1408	metallophosphoesterase
EXW39_18845	COG2116	formate transmembrane transporter activity
EXW39_18860	COG2217	Heavy metal translocating P-type atpase
EXW39_18865	COG2608	mercury ion transmembrane transporter activity
EXW39_18870	COG1937	Protein conserved in bacteria
EXW39_18890	COG2819	hydrolase of the alpha beta superfamily
EXW39_18895	COG1120	ATPase activity
EXW39_18900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW39_18905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW39_18910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW39_18915	COG0708	Exodeoxyribonuclease III
EXW39_18920	COG2169	Transcriptional regulator
EXW39_18925	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW39_18930	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW39_18935	COG2706	6-phosphogluconolactonase activity
EXW39_18940	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW39_18945	COG2364	Membrane
EXW39_18955	COG0346	lactoylglutathione lyase activity
EXW39_18960	COG3300	MHYT domain
EXW39_18960	COG5001	Diguanylate cyclase
EXW39_19000	COG1346	cytolysis
EXW39_19010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW39_19015	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW39_19015	COG0596	Alpha beta hydrolase
EXW39_19020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW39_19035	COG2188	Transcriptional regulator
EXW39_19040	COG2723	6-phospho-beta-galactosidase activity
EXW39_19050	COG3773	Cell wall hydrolase
EXW39_19060	COG1368	sulfuric ester hydrolase activity
EXW39_19065	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW39_19075	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW39_19085	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW39_19090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW39_19100	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW39_19105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW39_19110	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW39_19115	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW39_19115	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW39_19125	COG2359	stage V sporulation protein S
EXW39_19130	COG1692	metallophosphoesterase
EXW39_19135	COG1418	mRNA catabolic process
EXW39_19140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW39_19145	COG1058	Belongs to the CinA family
EXW39_19145	COG1546	Belongs to the CinA family
EXW39_19150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW39_19155	COG1426	Protein conserved in bacteria
EXW39_19170	COG0300	oxidoreductase activity
EXW39_19175	COG0612	Peptidase, M16
EXW39_19180	COG0612	Peptidase, M16
EXW39_19185	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW39_19190	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW39_19195	COG3845	ABC transporter
EXW39_19200	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW39_19205	COG2188	Transcriptional regulator
EXW39_19210	COG1674	ftsk spoiiie
EXW39_19220	COG0740	serine-type endopeptidase activity
EXW39_19225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW39_19235	COG0527	aspartate kinase activity
EXW39_19240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW39_19245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW39_19250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW39_19255	COG1873	PFAM PRC-barrel domain
EXW39_19260	COG0612	Peptidase, M16
EXW39_19265	COG0726	polysaccharide deacetylase
EXW39_19270	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW39_19280	COG0196	riboflavin kinase activity
EXW39_19290	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW39_19295	COG1550	Protein conserved in bacteria
EXW39_19300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW39_19305	COG1358	cellular component organization or biogenesis
EXW39_19310	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW39_19315	COG0195	Participates in both transcription termination and antitermination
EXW39_19320	COG0779	Required for maturation of 30S ribosomal subunits
EXW39_19330	COG0442	prolyl-tRNA aminoacylation
EXW39_19335	COG0750	zinc metalloprotease
EXW39_19345	COG4589	Belongs to the CDS family
EXW39_19355	COG0233	cytoplasmic translational termination
EXW39_19360	COG0528	UMP kinase activity
EXW39_19365	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW39_19370	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW39_19375	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW39_19380	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW39_19385	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW39_19390	COG4974	Belongs to the 'phage' integrase family
EXW39_19395	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW39_19400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW39_19405	COG0758	DNA mediated transformation
EXW39_19410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW39_19415	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW39_19420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW39_19435	COG0335	large ribosomal subunit rRNA binding
EXW39_19440	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW39_19445	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW39_19450	COG1837	Belongs to the UPF0109 family
EXW39_19460	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW39_19465	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EXW39_19470	COG0552	protein localization to endoplasmic reticulum
EXW39_19475	COG1196	nuclear chromosome segregation
EXW39_19480	COG0571	ribonuclease III activity
EXW39_19485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW39_19490	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_19495	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW39_19500	COG0416	fatty acid biosynthetic process
EXW39_19505	COG1349	DNA-binding transcription factor activity
EXW39_19505	COG2050	protein possibly involved in aromatic compounds catabolism
EXW39_19510	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW39_19515	COG1461	Dihydroxyacetone kinase
EXW39_19520	COG1302	Protein conserved in bacteria
EXW39_19535	COG1564	THIamine pyrophosphokinase
EXW39_19540	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW39_19550	COG0515	serine threonine protein kinase
EXW39_19550	COG2815	serine threonine protein kinase
EXW39_19555	COG0631	protein serine/threonine phosphatase activity
EXW39_19560	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW39_19565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW39_19565	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW39_19570	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW39_19575	COG0242	peptide deformylase activity
EXW39_19580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW39_19585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW39_19590	COG1758	RNA polymerase activity
EXW39_19605	COG1561	YicC-like family, N-terminal region
EXW39_19610	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW39_19620	COG0006	proline dipeptidase activity
EXW39_19655	COG4824	toxin secretion phage lysis holin
EXW39_19675	COG0167	dihydroorotate dehydrogenase activity
EXW39_19680	COG0543	2 iron, 2 sulfur cluster binding
EXW39_19685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW39_19695	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW39_19700	COG0540	Belongs to the ATCase OTCase family
EXW39_19710	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW39_19715	COG0564	pseudouridine synthase activity
EXW39_19720	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW39_19730	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW39_19735	COG3599	regulation of cell shape
EXW39_19740	COG2302	S4 RNA-binding domain
EXW39_19745	COG0762	integral membrane protein
EXW39_19750	COG1799	cell septum assembly
EXW39_19755	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW39_19765	COG1873	PFAM PRC-barrel domain
EXW39_19770	COG1191	sigma factor activity
EXW39_19775	COG1191	sigma factor activity
EXW39_19785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW39_19790	COG0849	cell division
EXW39_19795	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW39_19810	COG0772	Belongs to the SEDS family
EXW39_19815	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW39_19820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW39_19825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW39_19830	COG0768	penicillin binding
EXW39_19835	COG0768	penicillin binding
EXW39_19845	COG0275	rRNA processing
EXW39_19850	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW39_19855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW39_19860	COG0454	-acetyltransferase
EXW39_19870	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW39_19875	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW39_19880	COG1323	Belongs to the UPF0348 family
EXW39_19885	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW39_19890	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW39_19895	COG3314	Sporulation integral membrane protein YlbJ
EXW39_19900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EXW39_19905	COG0742	ribosomal rna small subunit methyltransferase
EXW39_19915	COG4471	UPF0298 protein
EXW39_19920	COG3679	Belongs to the UPF0342 family
EXW39_19925	COG0406	alpha-ribazole phosphatase activity
EXW39_19940	COG2340	Cysteine-rich secretory protein family
EXW39_19950	COG3336	cytochrome c oxidase
EXW39_19975	COG0109	protoheme IX farnesyltransferase activity
EXW39_19980	COG1612	heme a metabolic process
EXW39_19985	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW39_19995	COG0772	Belongs to the SEDS family
EXW39_20000	COG4838	Belongs to the UPF0358 family
EXW39_20005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW39_20010	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW39_20020	COG4896	Protein conserved in bacteria
EXW39_20035	COG1217	gtp-binding protein TYPA
EXW39_20045	COG0483	inositol monophosphate 1-phosphatase activity
EXW39_20055	COG4493	Belongs to the UPF0637 family
EXW39_20060	COG4476	Belongs to the UPF0223 family
EXW39_20070	COG1982	Orn Lys Arg decarboxylase major
EXW39_20115	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW39_20120	COG0022	dehydrogenase e1 component
EXW39_20125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW39_20140	COG0561	phosphatase activity
EXW39_20150	COG5503	Protein of unknown function (DUF1447)
EXW39_20155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW39_20160	COG0569	domain protein
EXW39_20170	COG1473	amidohydrolase
EXW39_20175	COG2171	N-acyltransferase activity
EXW39_20180	COG0583	DNA-binding transcription factor activity
EXW39_20185	COG0517	IMP dehydrogenase activity
EXW39_20195	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW39_20205	COG4703	Protein of unknown function (DUF1797)
EXW39_20220	COG2200	EAL domain
EXW39_20225	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_20230	COG1408	metallophosphoesterase
EXW39_20275	COG2814	Major facilitator Superfamily
EXW39_20285	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW39_20295	COG3209	COG3209 Rhs family protein
EXW39_20305	COG2205	protein histidine kinase activity
EXW39_20315	COG0436	Aminotransferase
EXW39_20320	COG1609	Transcriptional regulator
EXW39_20325	COG3833	ABC-type maltose transport systems, permease component
EXW39_20330	COG1175	transmembrane transport
EXW39_20335	COG2182	Extracellular solute-binding protein
EXW39_20345	COG0366	Alpha amylase catalytic
EXW39_20350	COG3842	ATPase activity
EXW39_20390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW39_20395	COG0183	Belongs to the thiolase family
EXW39_20435	COG1695	Transcriptional regulator
EXW39_20440	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_20450	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW39_20455	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW39_20460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW39_20465	COG0436	Aminotransferase
EXW39_20470	COG1850	ribulose-bisphosphate carboxylase activity
EXW39_20475	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW39_20480	COG0235	Class ii aldolase
EXW39_20485	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW39_20500	COG2084	Dehydrogenase
EXW39_20510	COG2199	diguanylate cyclase activity
EXW39_20515	COG0778	Nitroreductase
EXW39_20540	COG1263	PTS System
EXW39_20540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW39_20540	COG2190	(PTS) system
EXW39_20545	COG3711	transcriptional antiterminator
EXW39_20555	COG2188	Transcriptional regulator
EXW39_20560	COG0363	glucosamine-6-phosphate deaminase activity
EXW39_20565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW39_20575	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW39_20585	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW39_20595	COG1547	Domain of unknown function (DUF309)
EXW39_20605	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW39_20610	COG4086	secreted protein
EXW39_20615	COG0561	phosphatase activity
EXW39_20620	COG0697	spore germination
EXW39_20635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW39_20660	COG0733	neurotransmitter:sodium symporter activity
EXW39_20680	COG1686	Belongs to the peptidase S11 family
EXW39_20685	COG1725	Transcriptional regulator
EXW39_20690	COG1131	(ABC) transporter
EXW39_20710	COG1846	Transcriptional regulator
EXW39_20725	COG0598	Magnesium transport protein CorA
EXW39_20740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW39_20750	COG4974	Belongs to the 'phage' integrase family
EXW39_20760	COG0735	belongs to the Fur family
EXW39_20765	COG1300	Membrane
EXW39_20785	COG0667	Aldo Keto reductase
EXW39_20790	COG0656	L-ascorbic acid biosynthetic process
EXW39_20795	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW39_20795	COG0456	acetyltransferase
EXW39_20805	COG1525	nuclease
EXW39_20805	COG4085	toxin activity
EXW39_20805	COG0737	Belongs to the 5'-nucleotidase family
EXW39_20815	COG0596	Alpha beta hydrolase
EXW39_20820	COG2056	Na+-H+ antiporter family
EXW39_20825	COG1609	Transcriptional regulator
EXW39_20830	COG0456	acetyltransferase
EXW39_20835	COG1073	alpha beta
EXW39_20850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW39_20850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW39_20855	COG0307	riboflavin synthase, alpha
EXW39_20860	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW39_20860	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW39_20875	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW39_20880	COG4106	trans-aconitate 2-methyltransferase activity
EXW39_20885	COG1073	alpha beta
EXW39_20885	COG2226	methyltransferase
EXW39_20890	COG0156	8-amino-7-oxononanoate synthase activity
EXW39_20900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW39_20915	COG1757	Na H antiporter
EXW39_20920	COG0737	Belongs to the 5'-nucleotidase family
EXW39_20930	COG1522	sequence-specific DNA binding
EXW39_20965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW39_20975	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW39_20985	COG0300	oxidoreductase activity
EXW39_20990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW39_20995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW39_21000	COG1760	l-serine dehydratase
EXW39_21005	COG1760	l-serine dehydratase
EXW39_21015	COG1234	tRNA 3'-trailer cleavage
EXW39_21050	COG1131	(ABC) transporter
EXW39_21075	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW39_21080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW39_21090	COG1376	ErfK ybiS ycfS ynhG family protein
EXW39_21095	COG4129	membrane
EXW39_21100	COG1126	abc transporter atp-binding protein
EXW39_21105	COG0765	amino acid transport
EXW39_21110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW39_21120	COG2816	NAD+ diphosphatase activity
EXW39_21125	COG2323	membrane
EXW39_21130	COG0772	Belongs to the SEDS family
EXW39_21140	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW39_21145	COG0022	dehydrogenase e1 component
EXW39_21150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW39_21155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW39_21160	COG3426	butyrate kinase activity
EXW39_21170	COG0280	phosphate acetyltransferase
EXW39_21180	COG3829	transcription factor binding
EXW39_21180	COG3290	protein histidine kinase activity
EXW39_21190	COG0584	glycerophosphoryl diester phosphodiesterase
EXW39_21195	COG3093	addiction module antidote protein HigA
EXW39_21255	COG0745	RESPONSE REGULATOR receiver
EXW39_21265	COG0750	zinc metalloprotease
EXW39_21270	COG0497	DNA recombination
EXW39_21275	COG1438	arginine binding
EXW39_21280	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW39_21285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW39_21290	COG0142	geranyltranstransferase activity
EXW39_21295	COG1722	exodeoxyribonuclease VII activity
EXW39_21300	COG1570	exodeoxyribonuclease VII activity
EXW39_21305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW39_21310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW39_21315	COG1302	Protein conserved in bacteria
EXW39_21320	COG0439	Biotin carboxylase
EXW39_21325	COG0511	ligase activity, forming carbon-carbon bonds
EXW39_21370	COG3854	ATPases associated with a variety of cellular activities
EXW39_21390	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW39_21395	COG0006	proline dipeptidase activity
EXW39_21400	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW39_21410	COG3872	metal-dependent enzyme
EXW39_21420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW39_21425	COG1321	iron dependent repressor
EXW39_21455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW39_21465	COG1609	Transcriptional regulator
EXW39_21475	COG2076	Multidrug Resistance protein
EXW39_21480	COG2076	Multidrug Resistance protein
EXW39_21510	COG1131	(ABC) transporter
EXW39_21515	COG1725	Transcriptional regulator
EXW39_21530	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW39_21535	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW39_21540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW39_21545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW39_21575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW39_21600	COG4970	Tfp pilus assembly protein FimT
EXW39_21610	COG1459	type II secretion system
EXW39_21670	COG0646	methionine synthase
EXW39_21670	COG1410	methionine synthase
EXW39_21675	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW39_21675	COG0646	methionine synthase
EXW39_21680	COG0626	cystathionine gamma-synthase activity
EXW39_21685	COG0626	cystathionine gamma-synthase activity
EXW39_21700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW39_21710	COG1940	carbohydrate kinase activity
EXW39_21715	COG4483	Protein conserved in bacteria
EXW39_21720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW39_21725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW39_21730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW39_21735	COG0704	Plays a role in the regulation of phosphate uptake
EXW39_21745	COG0581	inorganic phosphate transmembrane transporter activity
EXW39_21750	COG0573	inorganic phosphate transmembrane transporter activity
EXW39_21755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW39_21760	COG0768	penicillin binding
EXW39_21765	COG0477	Major facilitator Superfamily
EXW39_21770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW39_21790	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW39_21795	COG0735	belongs to the Fur family
EXW39_21800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW39_21805	COG1121	(ABC) transporter
EXW39_21810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW39_21820	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW39_21835	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW39_21840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW39_21845	COG2384	SAM-dependent methyltransferase
EXW39_21855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW39_21860	COG0358	DNA primase activity
EXW39_21870	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW39_21875	COG0517	IMP dehydrogenase activity
EXW39_21880	COG1381	Involved in DNA repair and RecF pathway recombination
EXW39_21890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW39_21895	COG0295	cytidine deaminase activity
EXW39_21900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW39_21905	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW39_21910	COG1480	7TM receptor with intracellular HD hydrolase
EXW39_21915	COG1702	phosphate starvation-inducible protein PhoH
EXW39_21930	COG1610	YqeY-like protein
EXW39_21935	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW39_21940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW39_21945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW39_21955	COG0484	heat shock protein binding
EXW39_21960	COG0443	Heat shock 70 kDa protein
EXW39_21970	COG1420	regulation of RNA biosynthetic process
EXW39_21975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW39_21980	COG1733	regulation of RNA biosynthetic process
EXW39_21985	COG0481	GTPase activity
EXW39_21995	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW39_22000	COG0268	Binds directly to 16S ribosomal RNA
EXW39_22005	COG1466	dna polymerase III delta subunit
EXW39_22015	COG0658	competence protein
EXW39_22015	COG2333	competence protein COMEC
EXW39_22020	COG2131	deaminase
EXW39_22025	COG1596	polysaccharide export
EXW39_22025	COG1555	photosystem II stabilization
EXW39_22030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW39_22035	COG2226	methyltransferase
EXW39_22040	COG0799	negative regulation of ribosome biogenesis
EXW39_22045	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW39_22050	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW39_22055	COG1534	Rna-binding protein
EXW39_22060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW39_22065	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW39_22070	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW39_22080	COG0688	phosphatidylethanolamine metabolic process
EXW39_22090	COG1595	DNA-templated transcription, initiation
EXW39_22095	COG2357	RelA SpoT domain protein
EXW39_22105	COG1785	Belongs to the alkaline phosphatase family
EXW39_22115	COG2267	carboxylic ester hydrolase activity
EXW39_22150	COG1404	Belongs to the peptidase S8 family
EXW39_22155	COG3186	Phenylalanine-4-hydroxylase
EXW39_22160	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW39_22165	COG2514	catechol 2,3-dioxygenase activity
EXW39_22170	COG2259	Doxx family
EXW39_22210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW39_22220	COG1454	alcohol dehydrogenase
EXW39_22220	COG1012	belongs to the aldehyde dehydrogenase family
EXW39_22225	COG0626	cystathionine gamma-synthase activity
EXW39_22230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW39_22235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW39_22240	COG2226	methyltransferase
EXW39_22255	COG0768	penicillin binding
EXW39_22260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW39_22265	COG0572	uridine kinase
EXW39_22270	COG0826	peptidase U32
EXW39_22275	COG0826	peptidase U32
EXW39_22280	COG4122	O-methyltransferase activity
EXW39_22285	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW39_22295	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW39_22300	COG4472	Bacterial protein of unknown function (DUF965)
EXW39_22305	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW39_22315	COG0628	permease
EXW39_22335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW39_22345	COG0482	sulfurtransferase activity
EXW39_22350	COG1104	cysteine desulfurase activity
EXW39_22355	COG1959	2 iron, 2 sulfur cluster binding
EXW39_22360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW39_22370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW39_22375	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW39_22390	COG1490	D-aminoacyl-tRNA deacylase activity
EXW39_22395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW39_22400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW39_22405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW39_22405	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW39_22410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW39_22415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW39_22415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW39_22425	COG2244	polysaccharide biosynthetic process
EXW39_22430	COG2323	membrane
EXW39_22440	COG1862	Preprotein translocase
EXW39_22445	COG0343	queuine tRNA-ribosyltransferase activity
EXW39_22460	COG2255	four-way junction helicase activity
EXW39_22465	COG0632	four-way junction helicase activity
EXW39_22470	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW39_22495	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW39_22500	COG0157	Belongs to the NadC ModD family
EXW39_22505	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW39_22510	COG1104	cysteine desulfurase activity
EXW39_22515	COG1827	regulation of RNA biosynthetic process
EXW39_22520	COG2258	MOSC domain
EXW39_22525	COG0077	Prephenate dehydratase
EXW39_22530	COG0577	efflux transmembrane transporter activity
EXW39_22535	COG0577	efflux transmembrane transporter activity
EXW39_22540	COG1136	(ABC) transporter
EXW39_22545	COG5002	protein histidine kinase activity
EXW39_22550	COG0745	RESPONSE REGULATOR receiver
EXW39_22555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW39_22560	COG3290	protein histidine kinase activity
EXW39_22570	COG2868	ribosomal protein
EXW39_22580	COG1530	ribonuclease E activity
EXW39_22585	COG1994	Peptidase M50
EXW39_22590	COG0739	heme binding
EXW39_22595	COG2894	cell division
EXW39_22600	COG0850	regulation of cytokinetic process
EXW39_22615	COG1077	Cell shape determining protein MreB Mrl
EXW39_22620	COG2003	Belongs to the UPF0758 family
EXW39_22625	COG0424	maF-like protein
EXW39_22640	COG0285	dihydrofolate synthase activity
EXW39_22655	COG1388	LysM domain
EXW39_22660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW39_22665	COG0113	porphobilinogen synthase activity
EXW39_22675	COG1587	Uroporphyrinogen-III synthase
EXW39_22680	COG0181	hydroxymethylbilane synthase activity
EXW39_22685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW39_22690	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW39_22695	COG1846	Transcriptional regulator
EXW39_22700	COG1764	response to oxidative stress
EXW39_22705	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW39_22715	COG0470	DNA polymerase III
EXW39_22715	COG1067	ATP-dependent peptidase activity
EXW39_22725	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW39_22755	COG0622	Phosphoesterase
EXW39_22765	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW39_22770	COG5401	PFAM Sporulation and spore germination
EXW39_22780	COG2197	response regulator
EXW39_22785	COG2233	PERMEase
EXW39_22790	COG0402	S-adenosylhomocysteine deaminase activity
EXW39_22795	COG1983	PspC domain protein
EXW39_22800	COG1396	sequence-specific DNA binding
EXW39_22805	COG0697	spore germination
EXW39_22815	COG1959	2 iron, 2 sulfur cluster binding
EXW39_22820	COG1668	transmembrane transport
EXW39_22825	COG4152	abc transporter atp-binding protein
EXW39_22830	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW39_22835	COG1360	Flagellar Motor Protein
EXW39_22840	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW39_22850	COG1876	peptidase activity
EXW39_22855	COG0824	Thioesterase
EXW39_22860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW39_22865	COG1053	succinate dehydrogenase
EXW39_22870	COG2009	succinate dehydrogenase
EXW39_22875	COG1719	4-vinyl reductase, 4VR
EXW39_22880	COG0322	excinuclease ABC activity
EXW39_22885	COG3118	belongs to the thioredoxin family
EXW39_22890	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW39_22895	COG2086	electron transfer activity
EXW39_22900	COG1024	Enoyl-CoA hydratase
EXW39_22905	COG1309	transcriptional regulator
EXW39_22910	COG0318	PFAM AMP-dependent synthetase and ligase
EXW39_22930	COG2318	DinB family
EXW39_22950	COG1131	(ABC) transporter
EXW39_22955	COG2205	protein histidine kinase activity
EXW39_22960	COG0745	RESPONSE REGULATOR receiver
EXW39_22965	COG4895	conserved protein (DUF2196)
EXW39_22970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW39_22980	COG2329	Antibiotic biosynthesis monooxygenase
EXW39_22985	COG4509	Sortase family
EXW39_22990	COG1120	ATPase activity
EXW39_23005	COG5386	Cell surface protein
EXW39_23010	COG5386	Cell surface protein
EXW39_23015	COG1114	Component of the transport system for branched-chain amino acids
EXW39_23025	COG1193	negative regulation of DNA recombination
EXW39_23030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW39_23030	COG1796	DNA polymerase
EXW39_23035	COG1286	toxin biosynthetic process
EXW39_23040	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW39_23045	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW39_23070	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW39_23075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW39_23085	COG1418	mRNA catabolic process
EXW39_23105	COG2814	Major facilitator Superfamily
EXW39_23110	COG1566	PFAM secretion protein HlyD family protein
EXW39_23115	COG1309	transcriptional regulator
EXW39_23120	COG1363	Peptidase, m42
EXW39_23130	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW39_23145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW39_23155	COG1484	DNA-dependent DNA replication
EXW39_23160	COG3611	Membrane attachment protein
EXW39_23165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW39_23170	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW39_23175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW39_23180	COG0237	dephospho-CoA kinase activity
EXW39_23185	COG1971	Probably functions as a manganese efflux pump
EXW39_23195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW39_23195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW39_23200	COG5002	protein histidine kinase activity
EXW39_23205	COG0745	RESPONSE REGULATOR receiver
EXW39_23220	COG0039	L-malate dehydrogenase activity
EXW39_23225	COG0538	isocitrate dehydrogenase activity
EXW39_23230	COG0372	Belongs to the citrate synthase family
EXW39_23245	COG0628	permease
EXW39_23250	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW39_23260	COG0205	6-phosphofructokinase activity
EXW39_23270	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW39_23275	COG1725	Transcriptional regulator
EXW39_23280	COG0281	malic enzyme
EXW39_23285	COG0587	DNA-directed DNA polymerase activity
EXW39_23300	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW39_23320	COG4109	DRTGG domain
EXW39_23325	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW39_23330	COG0006	proline dipeptidase activity
EXW39_23355	COG0662	Cupin 2, conserved barrel domain protein
EXW39_23365	COG1476	TRANSCRIPTIONal
EXW39_23380	COG1028	Short-chain dehydrogenase reductase Sdr
EXW39_23385	COG0589	response to stress
EXW39_23410	COG0165	Argininosuccinate lyase
EXW39_23415	COG0137	argininosuccinate synthase activity
EXW39_23430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW39_23450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW39_23455	COG0827	DNA restriction-modification system
EXW39_23460	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW39_23465	COG3874	Sporulation protein YtfJ
EXW39_23480	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW39_23490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW39_23505	COG1104	cysteine desulfurase activity
EXW39_23510	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW39_23520	COG1309	transcriptional regulator
EXW39_23525	COG1956	GAF domain-containing protein
EXW39_23530	COG0626	cystathionine gamma-synthase activity
EXW39_23535	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW39_23560	COG1595	DNA-templated transcription, initiation
EXW39_23570	COG0110	maltose O-acetyltransferase activity
EXW39_23575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW39_23580	COG0454	-acetyltransferase
EXW39_23585	COG0517	IMP dehydrogenase activity
EXW39_23590	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW39_23605	COG0745	RESPONSE REGULATOR receiver
EXW39_23615	COG0666	response to abiotic stimulus
EXW39_23625	COG1970	mechanosensitive ion channel activity
EXW39_23650	COG1609	Transcriptional regulator
EXW39_23655	COG1605	Chorismate mutase
EXW39_23655	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW39_23660	COG1605	Chorismate mutase
EXW39_23660	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW39_23665	COG4851	CamS sex pheromone cAM373 precursor
EXW39_23670	COG3118	belongs to the thioredoxin family
EXW39_23680	COG2309	aminopeptidase activity
EXW39_23705	COG1695	Transcriptional regulator
EXW39_23715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW39_23725	COG1674	ftsk spoiiie
EXW39_23740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW39_23745	COG4848	Belongs to the UPF0354 family
EXW39_23750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW39_23755	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW39_23760	COG1363	Peptidase, m42
EXW39_23770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW39_23775	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW39_23785	COG0510	thiamine kinase activity
EXW39_23790	COG1523	belongs to the glycosyl hydrolase 13 family
EXW39_23800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW39_23805	COG1349	DNA-binding transcription factor activity
EXW39_23810	COG1187	pseudouridine synthase activity
EXW39_23815	COG2244	polysaccharide biosynthetic process
EXW39_23820	COG2081	HI0933 family
EXW39_23825	COG2814	Major facilitator Superfamily
EXW39_23835	COG3832	glyoxalase III activity
EXW39_23855	COG1329	Transcriptional regulator
EXW39_23880	COG0314	molybdopterin synthase activity
EXW39_23885	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW39_23890	COG0303	'Molybdopterin
EXW39_23895	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW39_23900	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW39_23905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW39_23930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW39_23940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW39_23980	COG0495	leucyl-tRNA aminoacylation
EXW39_23985	COG2814	Major facilitator Superfamily
EXW39_23990	COG0475	glutathione-regulated potassium exporter activity
EXW39_23995	COG0490	domain, Protein
EXW39_24000	COG0582	viral genome integration into host DNA
EXW39_24015	COG1136	(ABC) transporter
EXW39_24035	COG1242	4 iron, 4 sulfur cluster binding
EXW39_24040	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW39_24045	COG1794	racemase activity, acting on amino acids and derivatives
EXW39_24065	COG2267	carboxylic ester hydrolase activity
EXW39_24070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW39_24075	COG0671	phosphoesterase, PA-phosphatase related
EXW39_24080	COG0438	transferase activity, transferring glycosyl groups
EXW39_24085	COG0746	molybdenum cofactor guanylyltransferase activity
EXW39_24105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW39_24110	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW39_24155	COG5002	protein histidine kinase activity
EXW39_24160	COG3852	Histidine kinase
EXW39_24165	COG0753	catalase activity
EXW39_24170	COG2267	carboxylic ester hydrolase activity
EXW39_24180	COG1368	sulfuric ester hydrolase activity
EXW39_24190	COG4895	conserved protein (DUF2196)
EXW39_24205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW39_24210	COG1116	anion transmembrane transporter activity
EXW39_24215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW39_24235	COG0494	nUDIX hydrolase
EXW39_24280	COG2076	Multidrug Resistance protein
EXW39_24285	COG2076	Multidrug Resistance protein
EXW39_24290	COG0789	Transcriptional regulator
EXW39_24295	COG1854	S-ribosylhomocysteine lyase activity
EXW39_24305	COG0288	reversible hydration of carbon dioxide
EXW39_24310	COG1271	oxidase subunit
EXW39_24330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW39_24350	COG1842	Phage shock protein A
EXW39_24375	COG3859	Proton-coupled thiamine transporter YuaJ
EXW39_24380	COG5002	protein histidine kinase activity
EXW39_24385	COG0745	RESPONSE REGULATOR receiver
EXW39_24410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW39_24415	COG1597	lipid kinase activity
EXW39_24425	COG0577	efflux transmembrane transporter activity
EXW39_24430	COG1136	(ABC) transporter
EXW39_24435	COG2207	Transcriptional regulator
EXW39_24435	COG3708	Transcriptional regulator
EXW39_24445	COG1131	(ABC) transporter
EXW39_24455	COG5658	integral membrane protein
EXW39_24460	COG0640	Transcriptional regulator
EXW39_24465	COG0745	RESPONSE REGULATOR receiver
EXW39_24470	COG2205	protein histidine kinase activity
EXW39_24475	COG0577	efflux transmembrane transporter activity
EXW39_24480	COG0577	efflux transmembrane transporter activity
EXW39_24485	COG1136	(ABC) transporter
EXW39_24490	COG0577	efflux transmembrane transporter activity
EXW39_24505	COG2188	Transcriptional regulator
EXW39_24525	COG3964	amidohydrolase
EXW39_24545	COG4948	Mandelate Racemase Muconate Lactonizing
EXW39_24550	COG0318	PFAM AMP-dependent synthetase and ligase
EXW39_24555	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW39_24560	COG0596	Alpha beta hydrolase
EXW39_24565	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW39_24570	COG1169	isochorismate synthase
EXW39_24575	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW39_24580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW39_24585	COG1278	Cold shock
EXW39_24595	COG0789	Transcriptional regulator
EXW39_24610	COG0058	SHG alpha-glucan phosphorylase activity
EXW39_24620	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW39_24625	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW39_24630	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW39_24640	COG1404	Belongs to the peptidase S8 family
EXW39_24780	COG1285	pathogenesis
EXW39_24785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW39_24795	COG0166	Belongs to the GPI family
EXW39_24805	COG2155	Conserved Protein
EXW39_24810	COG1098	S1 RNA binding domain
EXW39_24815	COG0436	Aminotransferase
EXW39_24820	COG1522	sequence-specific DNA binding
EXW39_24825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW39_24830	COG2267	carboxylic ester hydrolase activity
EXW39_24840	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW39_24855	COG5018	Exonuclease
EXW39_24860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW39_24880	COG2050	protein possibly involved in aromatic compounds catabolism
EXW39_24890	COG1268	BioY protein
EXW39_24895	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW39_24900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW39_24910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW39_24915	COG3584	3D domain protein
EXW39_24930	COG1252	NADH dehydrogenase
EXW39_24935	COG0492	ferredoxin-NADP+ reductase activity
EXW39_24940	COG3708	Transcriptional regulator
EXW39_24955	COG1683	Conserved Protein
EXW39_24975	COG0316	Belongs to the HesB IscA family
EXW39_24980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW39_24985	COG4844	belongs to the
EXW39_24990	COG1252	NADH dehydrogenase
EXW39_24995	COG2274	protein secretion by the type I secretion system
EXW39_25000	COG0390	transport system, permease component
EXW39_25005	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW39_25045	COG4837	Protein of unknown function (DUF1462)
EXW39_25050	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW39_25060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW39_25065	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW39_25080	COG1136	(ABC) transporter
EXW39_25080	COG0577	efflux transmembrane transporter activity
EXW39_25085	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW39_25095	COG0647	UMP catabolic process
EXW39_25105	COG2445	Protein of unknown function DUF86
EXW39_25110	COG1494	fructose-1,6-bisphosphatase
EXW39_25125	COG4470	Protein conserved in bacteria
EXW39_25135	COG0789	Transcriptional regulator
EXW39_25140	COG4377	Putative membrane peptidase family (DUF2324)
EXW39_25160	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW39_25165	COG0739	heme binding
EXW39_25175	COG3377	Domain of unknown function (DUF1805)
EXW39_25180	COG0737	Belongs to the 5'-nucleotidase family
EXW39_25185	COG1695	Transcriptional regulator
EXW39_25195	COG0719	Fe-S assembly protein
EXW39_25200	COG0822	iron-sulfur transferase activity
EXW39_25205	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW39_25210	COG0719	Fe-S assembly protein
EXW39_25215	COG0396	ATPase activity
EXW39_25220	COG1464	Belongs to the NlpA lipoprotein family
EXW39_25225	COG1464	Belongs to the NlpA lipoprotein family
EXW39_25230	COG2011	ABC-type metal ion transport system permease component
EXW39_25245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW39_25250	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW39_25255	COG0509	glycine decarboxylation via glycine cleavage system
EXW39_25260	COG1393	Belongs to the ArsC family
EXW39_25330	COG1309	transcriptional regulator
EXW39_25335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW39_25340	COG1960	acyl-CoA dehydrogenase activity
EXW39_25345	COG0183	Belongs to the thiolase family
EXW39_25350	COG1024	Enoyl-CoA hydratase
EXW39_25350	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW39_25360	COG1686	Belongs to the peptidase S11 family
EXW39_25365	COG0506	proline dehydrogenase activity
EXW39_25375	COG0011	TIGRFAM Protein of
EXW39_25380	COG0840	transmembrane signaling receptor activity
EXW39_25395	COG2814	Major facilitator Superfamily
EXW39_25400	COG0531	amino acid
EXW39_25420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW39_25465	COG0586	Pfam SNARE associated Golgi protein
EXW39_25475	COG1376	ErfK ybiS ycfS ynhG family protein
EXW39_25480	COG0745	RESPONSE REGULATOR receiver
EXW39_25485	COG5002	protein histidine kinase activity
EXW39_25495	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW39_25505	COG0840	transmembrane signaling receptor activity
EXW39_25510	COG0840	transmembrane signaling receptor activity
EXW39_25515	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW39_25520	COG3227	Zinc metalloprotease (Elastase)
EXW39_25525	COG1741	Belongs to the pirin family
EXW39_25545	COG0475	glutathione-regulated potassium exporter activity
EXW39_25550	COG0490	domain, Protein
EXW39_25555	COG1115	amino acid carrier protein
EXW39_25560	COG0783	Belongs to the Dps family
EXW39_25570	COG2318	DinB family
EXW39_25575	COG1611	Belongs to the LOG family
EXW39_25585	COG1528	Iron-storage protein
EXW39_25590	COG2311	Membrane
EXW39_25595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW39_25600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW39_25605	COG1115	amino acid carrier protein
EXW39_25610	COG1115	amino acid carrier protein
EXW39_25615	COG2910	NAD(P)H-binding
EXW39_25645	COG0656	L-ascorbic acid biosynthetic process
EXW39_25650	COG2814	Major facilitator Superfamily
EXW39_25655	COG1733	regulation of RNA biosynthetic process
EXW39_25665	COG1252	NADH dehydrogenase
EXW39_25685	COG3290	protein histidine kinase activity
EXW39_25685	COG0840	transmembrane signaling receptor activity
EXW39_25720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW39_25730	COG1733	regulation of RNA biosynthetic process
EXW39_25735	COG0778	Nitroreductase
EXW39_25740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW39_25745	COG4224	UPF0291 protein
EXW39_25750	COG1522	sequence-specific DNA binding
EXW39_25755	COG0288	reversible hydration of carbon dioxide
EXW39_25760	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW39_25765	COG2233	PERMEase
EXW39_25810	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW39_25825	COG0557	exoribonuclease II activity
EXW39_25830	COG1647	Serine aminopeptidase, S33
EXW39_25835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW39_25840	COG1346	cytolysis
EXW39_25855	COG0148	phosphopyruvate hydratase activity
EXW39_25865	COG0149	triose-phosphate isomerase activity
EXW39_25870	COG0126	phosphoglycerate kinase activity
EXW39_25875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW39_25890	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW39_25920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW39_25935	COG2323	membrane
EXW39_25945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW39_25950	COG1481	regulation of sporulation
EXW39_25955	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW39_25960	COG1660	Displays ATPase and GTPase activities
EXW39_25965	COG1051	belongs to the nudix hydrolase family
EXW39_25975	COG0492	ferredoxin-NADP+ reductase activity
EXW39_25980	COG0457	Tetratricopeptide repeat
EXW39_25985	COG0110	maltose O-acetyltransferase activity
EXW39_25990	COG0546	phosphoglycolate phosphatase activity
EXW39_25995	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW39_26000	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW39_26005	COG1950	PFAM Membrane protein of
EXW39_26015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW39_26035	COG0789	Transcriptional regulator
EXW39_26070	COG0583	DNA-binding transcription factor activity
EXW39_26075	COG0789	Transcriptional regulator
EXW39_26080	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW39_26085	COG0488	(ABC) transporter
EXW39_26100	COG1132	(ABC) transporter
EXW39_26105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW39_26110	COG0793	Belongs to the peptidase S41A family
EXW39_26110	COG3409	Peptidoglycan-binding domain 1 protein
EXW39_26115	COG2177	Part of the ABC transporter FtsEX involved in
EXW39_26120	COG2884	Cell division ATP-binding protein ftsE
EXW39_26160	COG1278	Cold shock
EXW39_26165	COG1040	competence protein
EXW39_26170	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW39_26175	COG0791	NLP P60 protein
EXW39_26175	COG1388	LysM domain
EXW39_26180	COG1733	regulation of RNA biosynthetic process
EXW39_26185	COG1307	EDD domain protein, DegV family
EXW39_26190	COG1739	Uncharacterized protein family UPF0029
EXW39_26195	COG1316	TRANSCRIPTIONal
EXW39_26200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW39_26205	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW39_26210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW39_26220	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW39_26220	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW39_26240	COG1486	melibiose metabolic process
EXW39_26245	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW39_26250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW39_26255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW39_26270	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW39_26280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW39_26285	COG1301	dicarboxylic acid transport
EXW39_26305	COG1511	domain protein
EXW39_26310	COG0583	DNA-binding transcription factor activity
EXW39_26315	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW39_26320	COG1271	oxidase subunit
EXW39_26325	COG1294	oxidase, subunit
EXW39_26330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW39_26335	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW39_26340	COG1620	l-lactate permease
EXW39_26350	COG2389	metal-binding protein
EXW39_26365	COG1368	sulfuric ester hydrolase activity
EXW39_26375	COG0791	NLP P60 protein
EXW39_26375	COG1388	LysM domain
EXW39_26380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW39_26390	COG1215	transferase activity, transferring glycosyl groups
EXW39_26395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW39_26405	COG1388	LysM domain
EXW39_26405	COG3584	3D domain protein
EXW39_26430	COG4715	Zinc finger, swim domain protein
EXW39_26435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW39_26475	COG0577	efflux transmembrane transporter activity
EXW39_26480	COG1136	(ABC) transporter
EXW39_26515	COG5002	protein histidine kinase activity
EXW39_26515	COG3850	Histidine kinase
EXW39_26520	COG0745	RESPONSE REGULATOR receiver
EXW39_26565	COG0728	peptidoglycan biosynthetic process
EXW39_26590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW39_26595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW39_26600	COG4464	protein tyrosine phosphatase activity
EXW39_26605	COG0489	protein tyrosine kinase activity
EXW39_26610	COG3944	biosynthesis protein
EXW39_26615	COG0489	protein tyrosine kinase activity
EXW39_26630	COG1609	Transcriptional regulator
EXW39_26645	COG0739	heme binding
EXW39_26660	COG3279	Response regulator of the LytR AlgR family
EXW39_26665	COG2385	sporulation resulting in formation of a cellular spore
EXW39_26680	COG4836	Membrane
EXW39_26685	COG1007	ATP synthesis coupled electron transport
EXW39_26690	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW39_26695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW39_26700	COG0713	ATP synthesis coupled electron transport
EXW39_26705	COG0839	Belongs to the complex I subunit 6 family
EXW39_26715	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW39_26720	COG0649	NAD binding
EXW39_26725	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW39_26730	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW39_26735	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW39_26740	COG3300	MHYT domain
EXW39_26740	COG5001	Diguanylate cyclase
EXW39_26755	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW39_26760	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW39_26765	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW39_26770	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW39_26775	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW39_26780	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW39_26790	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW39_26815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW39_26825	COG0698	ribose 5-phosphate isomerase
EXW39_26835	COG2190	(PTS) system
EXW39_26840	COG2259	Doxx family
EXW39_26845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW39_26860	COG1971	Probably functions as a manganese efflux pump
EXW39_26865	COG0009	L-threonylcarbamoyladenylate synthase
EXW39_26880	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW39_26885	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW39_26890	COG1435	thymidine kinase activity
EXW39_26905	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW39_26915	COG1494	fructose-1,6-bisphosphatase
EXW39_26935	COG4821	SIS domain
EXW39_26940	COG0504	CTP synthase activity
EXW39_26945	COG3343	RNA polymerase activity
EXW39_26955	COG1960	acyl-CoA dehydrogenase activity
EXW39_26960	COG1960	acyl-CoA dehydrogenase activity
EXW39_26965	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW39_26970	COG0183	Belongs to the thiolase family
EXW39_26975	COG0247	lactate metabolic process
EXW39_26975	COG2181	nitrate reductase activity
EXW39_26985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW39_26990	COG4294	response to UV
EXW39_26995	COG3300	MHYT domain
EXW39_26995	COG5001	Diguanylate cyclase
EXW39_27010	COG3227	Zinc metalloprotease (Elastase)
EXW39_27015	COG2197	response regulator
EXW39_27020	COG4585	Histidine kinase
EXW39_27025	COG0842	Transport permease protein
EXW39_27030	COG1131	(ABC) transporter
EXW39_27035	COG0024	Methionine aminopeptidase
EXW39_27045	COG2234	aminopeptidase activity
EXW39_27065	COG4506	Protein conserved in bacteria
EXW39_27070	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW39_27090	COG0010	Belongs to the arginase family
EXW39_27095	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW39_27100	COG2814	Major facilitator Superfamily
EXW39_27105	COG0789	Transcriptional regulator
EXW39_27110	COG0584	glycerophosphoryl diester phosphodiesterase
EXW39_27115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW39_27125	COG1994	Peptidase M50
EXW39_27135	COG1078	dGTPase activity
EXW39_27140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW39_27145	COG1120	ATPase activity
EXW39_27150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW39_27155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW39_27160	COG4844	belongs to the
EXW39_27175	COG0280	phosphate acetyltransferase
EXW39_27180	COG3253	May function as heme-dependent peroxidase
EXW39_27190	COG3773	Cell wall hydrolase
EXW39_27200	COG2363	Small membrane protein
EXW39_27215	COG2233	PERMEase
EXW39_27220	COG0561	phosphatase activity
EXW39_27225	COG2814	Major facilitator Superfamily
EXW39_27230	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW39_27235	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW39_27240	COG1131	(ABC) transporter
EXW39_27245	COG2755	lipolytic protein G-D-S-L family
EXW39_27250	COG1609	Transcriptional regulator
EXW39_27260	COG0460	homoserine dehydrogenase
EXW39_27265	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW39_27270	COG2873	o-acetylhomoserine
EXW39_27280	COG1011	Hydrolase
EXW39_27285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW39_27295	COG2197	response regulator
EXW39_27300	COG2203	Gaf domain
EXW39_27300	COG4585	Histidine kinase
EXW39_27305	COG0351	phosphomethylpyrimidine kinase
EXW39_27310	COG3706	GGDEF domain
EXW39_27315	COG2879	small protein
EXW39_27320	COG1966	Carbon starvation protein
EXW39_27325	COG3279	Response regulator of the LytR AlgR family
EXW39_27330	COG0477	Major facilitator Superfamily
EXW39_27360	COG0840	transmembrane signaling receptor activity
EXW39_27370	COG1607	acyl-coa hydrolase
EXW39_27375	COG1216	Glycosyl transferase, family 2
EXW39_27385	COG1216	Glycosyl transferase, family 2
EXW39_27395	COG4485	Bacterial membrane protein, YfhO
EXW39_27400	COG0463	Glycosyl transferase, family 2
EXW39_27410	COG1309	transcriptional regulator
EXW39_27415	COG0488	(ABC) transporter
EXW39_27420	COG1309	transcriptional regulator
EXW39_27425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW39_27430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW39_27430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW39_27435	COG0628	permease
EXW39_27445	COG1380	Effector of murein hydrolase LrgA
EXW39_27450	COG3279	Response regulator of the LytR AlgR family
EXW39_27455	COG3275	phosphorelay sensor kinase activity
EXW39_27460	COG2814	Major facilitator Superfamily
EXW39_27465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW39_27470	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW39_27480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW39_27505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW39_27510	COG1272	protein, Hemolysin III
EXW39_27535	COG1164	Oligoendopeptidase f
EXW39_27545	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW39_27555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW39_27560	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW39_27565	COG4853	Protein conserved in bacteria
EXW39_27575	COG5002	protein histidine kinase activity
EXW39_27580	COG0745	RESPONSE REGULATOR receiver
EXW39_27610	COG0305	Participates in initiation and elongation during chromosome replication
EXW39_27615	COG0359	binds to the 23S rRNA
EXW39_27620	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW39_27625	COG4241	membrane
EXW39_27635	COG0629	single-stranded DNA binding
EXW39_27640	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW39_27645	COG0012	GTP binding
EXW39_27650	COG4481	Protein conserved in bacteria
EXW39_27655	COG0668	transmembrane transport
EXW39_27665	COG1475	DNA binding
EXW39_27670	COG1192	Involved in chromosome partitioning
EXW39_27675	COG1475	DNA binding
EXW39_27680	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW39_27685	COG0445	tRNA wobble uridine modification
EXW39_27690	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW39_27695	COG1847	R3H domain protein
EXW39_27700	COG0706	membrane insertase activity
EXW39_27705	COG0594	ribonuclease P activity
EXW39_27710	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW39_27750	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW39_27850	COG5484	DNA packaging
EXW39_27915	COG0756	dUTP diphosphatase activity
EXW39_27995	COG0419	ATPase involved in DNA repair
EXW39_28010	COG3646	Phage regulatory protein
EXW39_28060	COG1278	Cold shock
EXW39_28090	COG0582	viral genome integration into host DNA
EXW39_28135	COG1404	Belongs to the peptidase S8 family
EXW39_28210	COG4712	double-strand break repair protein
EXW39_28255	COG0673	inositol 2-dehydrogenase activity
EXW39_28260	COG0673	inositol 2-dehydrogenase activity
EXW39_28265	COG2169	Transcriptional regulator
EXW39_28330	COG2801	Transposase and inactivated derivatives
EXW39_28580	COG3344	reverse transcriptase
EXW39_28595	COG2311	Membrane
EXW39_28675	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW39_28680	COG0302	gtp cyclohydrolase
EXW39_28705	COG2226	methyltransferase
EXW39_28735	COG0277	FAD linked oxidase domain protein
EXW39_28740	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW39_28820	COG1923	regulation of RNA biosynthetic process
EXW39_28850	COG3621	Patatin-like phospholipase
EXW39_28880	COG4974	Belongs to the 'phage' integrase family
EXW39_28915	COG1196	nuclear chromosome segregation
EXW39_28930	COG0457	Tetratricopeptide repeat
EXW39_29040	COG0697	spore germination
EXW39_29065	COG2814	Major facilitator Superfamily
EXW39_29070	COG2234	aminopeptidase activity
EXW39_29080	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW39_29095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW39_29100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW39_29105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW39_29115	COG0456	acetyltransferase
EXW39_29205	COG0823	Involved in the tonB-independent uptake of proteins
EXW39_29270	COG5002	protein histidine kinase activity
EXW39_29275	COG0745	RESPONSE REGULATOR receiver
EXW39_29295	COG0577	efflux transmembrane transporter activity
EXW39_29300	COG1136	(ABC) transporter
EXW39_29310	COG0582	viral genome integration into host DNA
EXW39_29325	COG0475	glutathione-regulated potassium exporter activity
EXW39_29355	COG2002	toxin-antitoxin pair type II binding
EXW39_29385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW39_29420	COG2002	toxin-antitoxin pair type II binding
EXW39_29485	COG2801	Transposase and inactivated derivatives
EXW39_29515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW39_29525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW39_29530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW39_29535	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW39_29550	COG2002	toxin-antitoxin pair type II binding
EXW39_29585	COG1114	Component of the transport system for branched-chain amino acids
EXW39_29590	COG1115	amino acid carrier protein
EXW39_29640	COG0288	reversible hydration of carbon dioxide
EXW39_29645	COG0659	secondary active sulfate transmembrane transporter activity
EXW39_29680	COG2801	Transposase and inactivated derivatives
EXW39_29765	COG2002	toxin-antitoxin pair type II binding
EXW39_29820	COG2801	Transposase and inactivated derivatives
EXW39_29835	COG2002	toxin-antitoxin pair type II binding
EXW39_29840	COG1923	regulation of RNA biosynthetic process
EXW39_29970	COG0534	Mate efflux family protein
EXW39_29980	COG0582	viral genome integration into host DNA
EXW39_30075	COG1136	(ABC) transporter
EXW39_30095	COG0823	Involved in the tonB-independent uptake of proteins
EXW39_30170	COG0697	spore germination
EXW39_30270	COG1192	Involved in chromosome partitioning
EXW39_30310	COG2868	ribosomal protein