locus-tag	class	description
EXW36_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW36_00010	COG0592	DNA-directed DNA polymerase activity
EXW36_00015	COG2501	S4 domain
EXW36_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW36_00025	COG0187	DNA topoisomerase II activity
EXW36_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW36_00065	COG0516	GMP reductase activity
EXW36_00065	COG0517	IMP dehydrogenase activity
EXW36_00070	COG1686	Belongs to the peptidase S11 family
EXW36_00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW36_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW36_00100	COG1428	Deoxynucleoside kinase
EXW36_00105	COG1428	Deoxynucleoside kinase
EXW36_00110	COG1335	isochorismatase
EXW36_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW36_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW36_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW36_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW36_00180	COG1982	Orn Lys Arg decarboxylase major
EXW36_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW36_00190	COG0470	DNA polymerase III
EXW36_00195	COG1774	PSP1 C-terminal conserved region
EXW36_00200	COG4467	Involved in initiation control of chromosome replication
EXW36_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW36_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW36_00220	COG2002	toxin-antitoxin pair type II binding
EXW36_00230	COG0084	hydrolase, TatD family'
EXW36_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW36_00250	COG4466	Protein conserved in bacteria
EXW36_00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW36_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW36_00270	COG0251	oxidation-reduction process
EXW36_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW36_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW36_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW36_00305	COG2002	toxin-antitoxin pair type II binding
EXW36_00310	COG2244	polysaccharide biosynthetic process
EXW36_00315	COG3956	TIGRFAM MazG family protein
EXW36_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW36_00340	COG1098	S1 RNA binding domain
EXW36_00355	COG2208	phosphoserine phosphatase activity
EXW36_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW36_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW36_00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW36_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW36_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW36_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW36_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW36_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW36_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW36_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW36_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW36_00420	COG1396	sequence-specific DNA binding
EXW36_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW36_00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW36_00515	COG3880	PFAM UvrB UvrC protein
EXW36_00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW36_00525	COG0542	response to heat
EXW36_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW36_00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW36_00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW36_00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW36_00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW36_00560	COG1045	serine acetyltransferase
EXW36_00565	COG0215	cysteine-tRNA ligase activity
EXW36_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW36_00580	COG3688	RNA-binding protein containing a PIN domain
EXW36_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW36_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW36_00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW36_00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW36_00610	COG0081	regulation of translation
EXW36_00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW36_00620	COG0222	ribosome binding
EXW36_00625	COG2813	Specifically methylates the guanine in position
EXW36_00630	COG0085	RNA polymerase activity
EXW36_00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW36_00640	COG1358	cellular component organization or biogenesis
EXW36_00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW36_00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW36_00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW36_00665	COG0051	transcription antitermination factor activity, RNA binding
EXW36_00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW36_00675	COG0088	Forms part of the polypeptide exit tunnel
EXW36_00680	COG0089	rRNA binding
EXW36_00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW36_00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW36_00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW36_00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW36_00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW36_00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW36_00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW36_00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW36_00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW36_00760	COG1841	ribosomal large subunit assembly
EXW36_00765	COG0200	Binds to the 23S rRNA
EXW36_00770	COG0201	protein transport
EXW36_00775	COG0563	adenylate kinase activity
EXW36_00780	COG0024	Methionine aminopeptidase
EXW36_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW36_00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW36_00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW36_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW36_00835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW36_00840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW36_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW36_00855	COG0489	protein tyrosine kinase activity
EXW36_00865	COG2194	sulfuric ester hydrolase activity
EXW36_00870	COG0726	polysaccharide deacetylase
EXW36_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW36_00955	COG4856	YbbR-like protein
EXW36_00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW36_00975	COG0823	Involved in the tonB-independent uptake of proteins
EXW36_00975	COG4946	Tricorn protease homolog
EXW36_00975	COG1506	peptidase
EXW36_00990	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_00995	COG2011	ABC-type metal ion transport system permease component
EXW36_01005	COG1464	Belongs to the NlpA lipoprotein family
EXW36_01010	COG0604	alcohol dehydrogenase
EXW36_01020	COG0277	FAD linked oxidase domain protein
EXW36_01025	COG2271	Major facilitator Superfamily
EXW36_01035	COG2814	Major facilitator Superfamily
EXW36_01050	COG0601	transmembrane transport
EXW36_01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW36_01060	COG0444	Belongs to the ABC transporter superfamily
EXW36_01065	COG4608	Belongs to the ABC transporter superfamily
EXW36_01070	COG4166	transmembrane transport
EXW36_01080	COG2207	Transcriptional regulator
EXW36_01095	COG4166	transmembrane transport
EXW36_01100	COG4166	transmembrane transport
EXW36_01105	COG0656	L-ascorbic acid biosynthetic process
EXW36_01110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW36_01125	COG4149	molybdate abc transporter
EXW36_01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW36_01135	COG1910	domain protein
EXW36_01150	COG0697	spore germination
EXW36_01165	COG0204	Acyl-transferase
EXW36_01175	COG1609	Transcriptional regulator
EXW36_01185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_01200	COG5298	Protein conserved in bacteria
EXW36_01220	COG0488	(ABC) transporter
EXW36_01225	COG4585	Histidine kinase
EXW36_01230	COG2197	response regulator
EXW36_01235	COG1131	(ABC) transporter
EXW36_01240	COG0842	Transport permease protein
EXW36_01240	COG1511	domain protein
EXW36_01245	COG0842	Transport permease protein
EXW36_01255	COG0747	negative chemotaxis
EXW36_01265	COG0601	transmembrane transport
EXW36_01270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW36_01275	COG0444	Belongs to the ABC transporter superfamily
EXW36_01280	COG4608	Belongs to the ABC transporter superfamily
EXW36_01285	COG0561	phosphatase activity
EXW36_01310	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW36_01315	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW36_01325	COG0531	amino acid
EXW36_01330	COG2814	Major facilitator Superfamily
EXW36_01340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW36_01350	COG4294	response to UV
EXW36_01355	COG0705	Rhomboid family
EXW36_01360	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW36_01365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW36_01375	COG0864	Transcriptional regulator
EXW36_01380	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW36_01385	COG2183	response to ionizing radiation
EXW36_01485	COG0802	atpase or kinase
EXW36_01490	COG1214	PFAM Peptidase M22, glycoprotease
EXW36_01495	COG0456	acetyltransferase
EXW36_01505	COG0488	(ABC) transporter
EXW36_01510	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW36_01520	COG1266	CAAX protease self-immunity
EXW36_01525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW36_01530	COG0459	protein refolding
EXW36_01535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW36_01535	COG0519	Catalyzes the synthesis of GMP from XMP
EXW36_01540	COG2252	PERMEase
EXW36_01550	COG5002	protein histidine kinase activity
EXW36_01570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW36_01630	COG2205	protein histidine kinase activity
EXW36_01635	COG0745	RESPONSE REGULATOR receiver
EXW36_01655	COG0697	spore germination
EXW36_01680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW36_01685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW36_01690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW36_01695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW36_01700	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW36_01705	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW36_01710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW36_01715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW36_01720	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW36_01725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW36_01730	COG0138	bifunctional purine biosynthesis protein purh
EXW36_01735	COG0151	Belongs to the GarS family
EXW36_01755	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW36_01760	COG0210	DNA helicase
EXW36_01765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW36_01770	COG4851	CamS sex pheromone cAM373 precursor
EXW36_01780	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_01785	COG1335	isochorismatase
EXW36_01795	COG2011	ABC-type metal ion transport system permease component
EXW36_01800	COG1464	Belongs to the NlpA lipoprotein family
EXW36_01815	COG0003	Pfam Anion-transporting ATPase
EXW36_01820	COG1846	Transcriptional regulator
EXW36_01825	COG4682	membrane
EXW36_01835	COG0154	amidase activity
EXW36_01840	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW36_01845	COG1597	lipid kinase activity
EXW36_01850	COG0546	phosphoglycolate phosphatase activity
EXW36_01855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW36_01865	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_01870	COG2076	Multidrug Resistance protein
EXW36_01875	COG2309	aminopeptidase activity
EXW36_01890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_01900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW36_01905	COG5002	protein histidine kinase activity
EXW36_01910	COG4807	Protein conserved in bacteria
EXW36_01935	COG1757	Na H antiporter
EXW36_01940	COG1473	amidohydrolase
EXW36_01955	COG0450	alkyl hydroperoxide reductase
EXW36_01965	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW36_01975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_01980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_01985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_01990	COG0492	ferredoxin-NADP+ reductase activity
EXW36_02000	COG0166	Belongs to the GPI family
EXW36_02025	COG5002	protein histidine kinase activity
EXW36_02045	COG3541	Predicted nucleotidyltransferase
EXW36_02050	COG2814	Major facilitator Superfamily
EXW36_02055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW36_02055	COG0723	plastoquinol--plastocyanin reductase activity
EXW36_02065	COG0765	amino acid transport
EXW36_02070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW36_02080	COG0840	transmembrane signaling receptor activity
EXW36_02085	COG0277	FAD linked oxidase domain protein
EXW36_02090	COG0366	Alpha amylase catalytic
EXW36_02095	COG2190	(PTS) system
EXW36_02095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW36_02095	COG1263	PTS System
EXW36_02115	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW36_02120	COG0352	thiamine-phosphate diphosphorylase activity
EXW36_02125	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW36_02140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW36_02145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW36_02150	COG1116	anion transmembrane transporter activity
EXW36_02155	COG0488	(ABC) transporter
EXW36_02200	COG2270	Major facilitator Superfamily
EXW36_02230	COG2310	stress, protein
EXW36_02235	COG2310	stress, protein
EXW36_02240	COG2310	stress, protein
EXW36_02245	COG0861	Integral membrane protein TerC family
EXW36_02255	COG3853	Toxic anion resistance protein (TelA)
EXW36_02265	COG4840	Belongs to the UPF0435 family
EXW36_02270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW36_02280	COG1295	ribonuclease BN
EXW36_02285	COG2217	Heavy metal translocating P-type atpase
EXW36_02290	COG0697	spore germination
EXW36_02310	COG0586	Pfam SNARE associated Golgi protein
EXW36_02325	COG3871	stress protein (general stress protein 26)
EXW36_02330	COG0387	Pfam Sodium calcium exchanger
EXW36_02340	COG0535	radical SAM domain protein
EXW36_02360	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW36_02380	COG3829	transcription factor binding
EXW36_02390	COG0833	amino acid
EXW36_02395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW36_02415	COG2066	Belongs to the glutaminase family
EXW36_02420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW36_02420	COG1263	PTS System
EXW36_02425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW36_02440	COG1216	Glycosyl transferase, family 2
EXW36_02450	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW36_02450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW36_02455	COG0463	Glycosyl transferase, family 2
EXW36_02470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW36_02475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW36_02490	COG1228	amidohydrolase
EXW36_02495	COG1090	epimerase
EXW36_02500	COG2137	regulation of response to DNA damage stimulus
EXW36_02525	COG1988	membrane-bound metal-dependent
EXW36_02530	COG1194	a g-specific adenine glycosylase
EXW36_02550	COG3557	Belongs to the UPF0374 family
EXW36_02555	COG1132	(ABC) transporter
EXW36_02560	COG4129	membrane
EXW36_02565	COG0067	glutamate synthase
EXW36_02565	COG0069	glutamate synthase activity
EXW36_02565	COG0070	glutamate synthase
EXW36_02570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW36_02575	COG4555	ABC transporter
EXW36_02595	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW36_02600	COG0735	belongs to the Fur family
EXW36_02705	COG4974	Belongs to the 'phage' integrase family
EXW36_02785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW36_02790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW36_02810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW36_02820	COG2766	serine protein kinase
EXW36_02825	COG2718	Belongs to the UPF0229 family
EXW36_02840	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW36_02845	COG2268	Band 7 protein
EXW36_02855	COG3290	protein histidine kinase activity
EXW36_02860	COG4565	transcriptional regulatory protein
EXW36_02865	COG2851	Citrate transporter
EXW36_02895	COG3842	ATPase activity
EXW36_02900	COG1175	transmembrane transport
EXW36_02905	COG0395	ABC-type sugar transport system, permease component
EXW36_02915	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW36_02920	COG0745	RESPONSE REGULATOR receiver
EXW36_02925	COG5002	protein histidine kinase activity
EXW36_02935	COG4990	cell redox homeostasis
EXW36_02945	COG3290	protein histidine kinase activity
EXW36_02950	COG4565	transcriptional regulatory protein
EXW36_02955	COG3493	citrate carrier protein
EXW36_02960	COG0281	malic enzyme
EXW36_02970	COG0697	spore germination
EXW36_02975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_02985	COG5002	protein histidine kinase activity
EXW36_02990	COG0745	RESPONSE REGULATOR receiver
EXW36_02995	COG0456	acetyltransferase
EXW36_03000	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW36_03005	COG3383	formate dehydrogenase (NAD+) activity
EXW36_03010	COG2427	Protein of unknown function (DUF1641)
EXW36_03025	COG0531	amino acid
EXW36_03035	COG0640	Transcriptional regulator
EXW36_03040	COG2217	Heavy metal translocating P-type atpase
EXW36_03045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW36_03060	COG3227	Zinc metalloprotease (Elastase)
EXW36_03080	COG2720	vancomycin resistance protein
EXW36_03085	COG1316	TRANSCRIPTIONal
EXW36_03090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_03095	COG0346	lactoylglutathione lyase activity
EXW36_03100	COG1253	flavin adenine dinucleotide binding
EXW36_03105	COG1027	Aspartate ammonia-lyase
EXW36_03110	COG1620	l-lactate permease
EXW36_03115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_03130	COG3104	oligopeptide transport
EXW36_03135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_03145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_03160	COG0156	8-amino-7-oxononanoate synthase activity
EXW36_03165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW36_03175	COG4548	von Willebrand factor, type A
EXW36_03180	COG0714	Associated with various cellular activities
EXW36_03200	COG0531	amino acid
EXW36_03205	COG2188	Transcriptional regulator
EXW36_03210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW36_03210	COG1263	PTS System
EXW36_03215	COG0366	Alpha amylase catalytic
EXW36_03230	COG0697	spore germination
EXW36_03235	COG4585	Histidine kinase
EXW36_03240	COG2197	response regulator
EXW36_03245	COG1404	Belongs to the peptidase S8 family
EXW36_03260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW36_03265	COG1115	amino acid carrier protein
EXW36_03270	COG1126	abc transporter atp-binding protein
EXW36_03275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW36_03280	COG0765	amino acid transport
EXW36_03285	COG0765	amino acid transport
EXW36_03290	COG0833	amino acid
EXW36_03305	COG2378	regulation of single-species biofilm formation
EXW36_03310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW36_03315	COG5002	protein histidine kinase activity
EXW36_03330	COG0659	secondary active sulfate transmembrane transporter activity
EXW36_03345	COG0747	negative chemotaxis
EXW36_03355	COG0601	transmembrane transport
EXW36_03360	COG4608	Belongs to the ABC transporter superfamily
EXW36_03370	COG2271	Major facilitator Superfamily
EXW36_03375	COG1846	Transcriptional regulator
EXW36_03380	COG0477	Major facilitator Superfamily
EXW36_03385	COG1609	Transcriptional regulator
EXW36_03390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW36_03395	COG1869	D-ribose catabolic process
EXW36_03405	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW36_03410	COG1879	ABC-type sugar transport system periplasmic component
EXW36_03440	COG1063	alcohol dehydrogenase
EXW36_03455	COG3568	Endonuclease Exonuclease Phosphatase
EXW36_03485	COG0840	transmembrane signaling receptor activity
EXW36_03490	COG3583	domain protein
EXW36_03490	COG3584	3D domain protein
EXW36_03495	COG1476	TRANSCRIPTIONal
EXW36_03515	COG3104	oligopeptide transport
EXW36_03520	COG1114	Component of the transport system for branched-chain amino acids
EXW36_03535	COG1113	amino acid transport
EXW36_03540	COG2252	PERMEase
EXW36_03565	COG0475	glutathione-regulated potassium exporter activity
EXW36_03565	COG0569	domain protein
EXW36_03575	COG1845	cytochrome c oxidase, subunit III
EXW36_03580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW36_03590	COG0833	amino acid
EXW36_03595	COG4990	cell redox homeostasis
EXW36_03610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW36_03615	COG0697	spore germination
EXW36_03620	COG0531	amino acid
EXW36_03630	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW36_03635	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW36_03645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW36_03650	COG0573	inorganic phosphate transmembrane transporter activity
EXW36_03655	COG0581	inorganic phosphate transmembrane transporter activity
EXW36_03665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW36_03785	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW36_03800	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW36_03800	COG3103	Sh3 type 3 domain protein
EXW36_03800	COG4991	sh3 domain protein
EXW36_03805	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW36_03810	COG1116	anion transmembrane transporter activity
EXW36_03815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW36_03820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW36_03825	COG0352	thiamine-phosphate diphosphorylase activity
EXW36_03830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW36_03835	COG2104	thiamine diphosphate biosynthetic process
EXW36_03840	COG2022	thiamine diphosphate biosynthetic process
EXW36_03845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW36_03850	COG0351	phosphomethylpyrimidine kinase
EXW36_03875	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW36_03880	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW36_03885	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW36_03890	COG2205	protein histidine kinase activity
EXW36_03895	COG2814	Major facilitator Superfamily
EXW36_03900	COG1846	Transcriptional regulator
EXW36_03920	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW36_03925	COG1129	ABC transporter
EXW36_03930	COG1879	ABC-type sugar transport system periplasmic component
EXW36_03935	COG2252	PERMEase
EXW36_03940	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_03955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW36_03960	COG1621	beta-fructofuranosidase activity
EXW36_03965	COG1263	PTS System
EXW36_03965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW36_03970	COG1609	Transcriptional regulator
EXW36_04020	COG0778	Nitroreductase
EXW36_04025	COG2719	SpoVR family
EXW36_04050	COG1937	Protein conserved in bacteria
EXW36_04055	COG0425	Belongs to the sulfur carrier protein TusA family
EXW36_04055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW36_04060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_04060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW36_04065	COG0425	Belongs to the sulfur carrier protein TusA family
EXW36_04070	COG0425	Belongs to the sulfur carrier protein TusA family
EXW36_04070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW36_04075	COG2210	Belongs to the sulfur carrier protein TusA family
EXW36_04080	COG0730	response to heat
EXW36_04090	COG1316	TRANSCRIPTIONal
EXW36_04095	COG0604	alcohol dehydrogenase
EXW36_04100	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW36_04105	COG0604	alcohol dehydrogenase
EXW36_04110	COG2814	Major facilitator Superfamily
EXW36_04120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW36_04120	COG3711	transcriptional antiterminator
EXW36_04125	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW36_04130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW36_04155	COG1388	LysM domain
EXW36_04155	COG3584	3D domain protein
EXW36_04160	COG0577	efflux transmembrane transporter activity
EXW36_04165	COG1136	(ABC) transporter
EXW36_04175	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW36_04190	COG1114	Component of the transport system for branched-chain amino acids
EXW36_04195	COG3546	catalase activity
EXW36_04225	COG0586	Pfam SNARE associated Golgi protein
EXW36_04255	COG0531	amino acid
EXW36_04260	COG0475	glutathione-regulated potassium exporter activity
EXW36_04270	COG1737	Transcriptional regulator
EXW36_04275	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW36_04280	COG1263	PTS System
EXW36_04280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW36_04290	COG2259	Doxx family
EXW36_04310	COG0697	spore germination
EXW36_04315	COG1522	sequence-specific DNA binding
EXW36_04325	COG0300	oxidoreductase activity
EXW36_04340	COG2076	Multidrug Resistance protein
EXW36_04345	COG1309	transcriptional regulator
EXW36_04350	COG2814	Major facilitator Superfamily
EXW36_04355	COG1733	regulation of RNA biosynthetic process
EXW36_04365	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW36_04375	COG4533	DNA binding
EXW36_04380	COG2211	Major facilitator Superfamily
EXW36_04395	COG0531	amino acid
EXW36_04400	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_04405	COG1132	(ABC) transporter
EXW36_04410	COG1132	(ABC) transporter
EXW36_04415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW36_04420	COG0765	amino acid transport
EXW36_04425	COG1126	abc transporter atp-binding protein
EXW36_04440	COG0189	ligase activity
EXW36_04450	COG4399	Belongs to the UPF0754 family
EXW36_04455	COG3679	Belongs to the UPF0342 family
EXW36_04470	COG0028	Belongs to the TPP enzyme family
EXW36_04475	COG3527	Alpha-acetolactate decarboxylase
EXW36_04480	COG0463	Glycosyl transferase, family 2
EXW36_04485	COG1216	Glycosyl transferase, family 2
EXW36_04490	COG2094	Belongs to the DNA glycosylase MPG family
EXW36_04495	COG0561	phosphatase activity
EXW36_04505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW36_04510	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_04520	COG0659	secondary active sulfate transmembrane transporter activity
EXW36_04525	COG0653	protein targeting
EXW36_04530	COG2244	polysaccharide biosynthetic process
EXW36_04550	COG1696	Membrane protein involved in D-alanine export
EXW36_04565	COG1024	Enoyl-CoA hydratase
EXW36_04580	COG1363	Peptidase, m42
EXW36_04595	COG2318	DinB family
EXW36_04615	COG0579	oxidoreductase
EXW36_04645	COG0601	transmembrane transport
EXW36_04650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW36_04655	COG0444	Belongs to the ABC transporter superfamily
EXW36_04660	COG4608	Belongs to the ABC transporter superfamily
EXW36_04755	COG0477	Major facilitator Superfamily
EXW36_04760	COG3290	protein histidine kinase activity
EXW36_04765	COG4565	transcriptional regulatory protein
EXW36_04770	COG3181	Tripartite tricarboxylate transporter family receptor
EXW36_04795	COG0789	Transcriptional regulator
EXW36_04795	COG4978	Transcriptional regulator
EXW36_04810	COG0305	Participates in initiation and elongation during chromosome replication
EXW36_04840	COG0477	Major facilitator Superfamily
EXW36_04925	COG2814	Major facilitator Superfamily
EXW36_04930	COG0640	Transcriptional regulator
EXW36_04950	COG2376	Dihydroxyacetone kinase
EXW36_04960	COG2376	Dihydroxyacetone kinase
EXW36_04975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW36_05015	COG0076	glutamate decarboxylase activity
EXW36_05040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW36_05045	COG1278	Cold shock
EXW36_05055	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EXW36_05055	COG3266	domain, Protein
EXW36_05055	COG4932	domain protein
EXW36_05065	COG2409	Drug exporters of the RND superfamily
EXW36_05090	COG4085	toxin activity
EXW36_05090	COG0737	Belongs to the 5'-nucleotidase family
EXW36_05090	COG1525	nuclease
EXW36_05110	COG1309	transcriptional regulator
EXW36_05115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW36_05120	COG4974	Belongs to the 'phage' integrase family
EXW36_05125	COG2814	Major facilitator Superfamily
EXW36_05130	COG0583	DNA-binding transcription factor activity
EXW36_05150	COG0825	malonyl-CoA metabolic process
EXW36_05170	COG3237	CsbD-like
EXW36_05190	COG2172	sigma factor antagonist activity
EXW36_05195	COG1191	sigma factor activity
EXW36_05205	COG2208	phosphoserine phosphatase activity
EXW36_05210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW36_05215	COG0784	Response regulator, receiver
EXW36_05215	COG2205	protein histidine kinase activity
EXW36_05215	COG5002	protein histidine kinase activity
EXW36_05260	COG2807	transmembrane transport
EXW36_05265	COG2186	Transcriptional regulator
EXW36_05270	COG4585	Histidine kinase
EXW36_05275	COG2197	response regulator
EXW36_05305	COG0420	3'-5' exonuclease activity
EXW36_05310	COG4717	serine-type aminopeptidase activity
EXW36_05315	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW36_05325	COG0346	lactoylglutathione lyase activity
EXW36_05340	COG2267	carboxylic ester hydrolase activity
EXW36_05355	COG3620	sequence-specific DNA binding
EXW36_05360	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW36_05365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW36_05370	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW36_05375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW36_05380	COG1595	DNA-templated transcription, initiation
EXW36_05395	COG3973	AAA domain
EXW36_05400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW36_05415	COG1846	Transcriptional regulator
EXW36_05425	COG0537	adenosine 5'-monophosphoramidase activity
EXW36_05430	COG1131	(ABC) transporter
EXW36_05435	COG4473	ABC transporter
EXW36_05450	COG0247	lactate metabolic process
EXW36_05455	COG1139	Iron-sulfur cluster binding protein
EXW36_05460	COG1556	Lactate utilization protein
EXW36_05480	COG3402	PFAM membrane-flanked domain
EXW36_05485	COG3428	Bacterial PH domain
EXW36_05515	COG3402	PFAM membrane-flanked domain
EXW36_05520	COG3428	Bacterial PH domain
EXW36_05525	COG2329	Antibiotic biosynthesis monooxygenase
EXW36_05530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW36_05535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW36_05540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW36_05545	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW36_05565	COG1309	transcriptional regulator
EXW36_05570	COG1511	domain protein
EXW36_05605	COG2378	regulation of single-species biofilm formation
EXW36_05610	COG1609	Transcriptional regulator
EXW36_05620	COG1234	tRNA 3'-trailer cleavage
EXW36_05625	COG0095	Lipoate-protein ligase
EXW36_05635	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_05650	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW36_05660	COG4208	sulfate ABC transporter
EXW36_05675	COG1408	metallophosphoesterase
EXW36_05680	COG1078	dGTPase activity
EXW36_05700	COG3708	Transcriptional regulator
EXW36_05700	COG2207	Transcriptional regulator
EXW36_05705	COG2205	protein histidine kinase activity
EXW36_05710	COG0745	RESPONSE REGULATOR receiver
EXW36_05725	COG0501	Belongs to the peptidase M48B family
EXW36_05730	COG0697	spore germination
EXW36_05755	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW36_05760	COG2224	Isocitrate lyase
EXW36_05770	COG1278	Cold shock
EXW36_05780	COG4903	ComK protein
EXW36_05785	COG0398	Pfam SNARE associated Golgi protein
EXW36_05795	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW36_05800	COG1074	ATP-dependent DNA helicase activity
EXW36_05850	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW36_05875	COG0367	asparagine synthase
EXW36_05885	COG0753	catalase activity
EXW36_05890	COG0004	ammonium transporteR
EXW36_05900	COG1666	GTP binding
EXW36_05905	COG2996	Protein conserved in bacteria
EXW36_05910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW36_05920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_05935	COG0561	phosphatase activity
EXW36_05955	COG2267	carboxylic ester hydrolase activity
EXW36_05970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW36_05975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW36_05980	COG5504	Zn-dependent protease
EXW36_05990	COG0180	Tryptophanyl-tRNA synthetase
EXW36_06000	COG4166	transmembrane transport
EXW36_06005	COG0601	transmembrane transport
EXW36_06010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW36_06015	COG0444	Belongs to the ABC transporter superfamily
EXW36_06020	COG4608	Belongs to the ABC transporter superfamily
EXW36_06025	COG0534	Mate efflux family protein
EXW36_06030	COG4166	transmembrane transport
EXW36_06045	COG0861	Integral membrane protein TerC family
EXW36_06050	COG4862	establishment of competence for transformation
EXW36_06055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW36_06065	COG1164	Oligoendopeptidase f
EXW36_06080	COG2346	COG2346, Truncated hemoglobins
EXW36_06085	COG4116	CYTH
EXW36_06095	COG2357	RelA SpoT domain protein
EXW36_06105	COG0564	pseudouridine synthase activity
EXW36_06115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW36_06120	COG0772	Belongs to the SEDS family
EXW36_06125	COG1216	Glycosyl transferase, family 2
EXW36_06145	COG0457	Tetratricopeptide repeat
EXW36_06145	COG0463	Glycosyl transferase, family 2
EXW36_06165	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW36_06180	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW36_06225	COG2153	protein acetylation
EXW36_06230	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW36_06235	COG2382	esterase
EXW36_06260	COG5492	domain, Protein
EXW36_06265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW36_06275	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW36_06275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW36_06280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW36_06285	COG0134	indole-3-glycerol-phosphate synthase activity
EXW36_06290	COG0135	phosphoribosylanthranilate isomerase activity
EXW36_06295	COG0133	tryptophan synthase activity
EXW36_06300	COG0159	tryptophan synthase activity
EXW36_06310	COG1620	l-lactate permease
EXW36_06315	COG5634	Uncharacterized conserved protein (DUF2278)
EXW36_06360	COG2226	methyltransferase
EXW36_06380	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW36_06385	COG0567	Dehydrogenase, E1 component
EXW36_06390	COG1476	TRANSCRIPTIONal
EXW36_06430	COG0582	viral genome integration into host DNA
EXW36_06510	COG0457	Tetratricopeptide repeat
EXW36_06550	COG1686	Belongs to the peptidase S11 family
EXW36_06555	COG0681	Belongs to the peptidase S26 family
EXW36_06590	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_06600	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW36_06605	COG1177	transmembrane transport
EXW36_06610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW36_06620	COG2409	Drug exporters of the RND superfamily
EXW36_06630	COG0564	pseudouridine synthase activity
EXW36_06640	COG2340	Cysteine-rich secretory protein family
EXW36_06645	COG0247	lactate metabolic process
EXW36_06650	COG0277	FAD linked oxidase domain protein
EXW36_06655	COG3835	regulator
EXW36_06665	COG0745	RESPONSE REGULATOR receiver
EXW36_06670	COG5002	protein histidine kinase activity
EXW36_06675	COG2186	Transcriptional regulator
EXW36_06680	COG0247	lactate metabolic process
EXW36_06685	COG1139	Iron-sulfur cluster binding protein
EXW36_06690	COG1556	Lactate utilization protein
EXW36_06695	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW36_06705	COG2116	formate transmembrane transporter activity
EXW36_06710	COG0861	Integral membrane protein TerC family
EXW36_06715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW36_06725	COG2030	dehydratase
EXW36_06745	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_06750	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW36_06760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW36_06775	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW36_06780	COG3842	ATPase activity
EXW36_06790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW36_06795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW36_06805	COG1349	DNA-binding transcription factor activity
EXW36_06815	COG0235	Class ii aldolase
EXW36_06825	COG2861	carbohydrate metabolic process
EXW36_06835	COG3852	Histidine kinase
EXW36_06840	COG1846	Transcriptional regulator
EXW36_06850	COG2318	DinB family
EXW36_06855	COG5002	protein histidine kinase activity
EXW36_06860	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW36_06865	COG0720	synthase
EXW36_06875	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW36_06880	COG4873	Protein conserved in bacteria
EXW36_06895	COG0456	acetyltransferase
EXW36_06910	COG1780	Probably involved in ribonucleotide reductase function
EXW36_06925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW36_06930	COG0531	amino acid
EXW36_06935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW36_06950	COG2204	response regulator
EXW36_06955	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_06965	COG1725	Transcriptional regulator
EXW36_06970	COG1131	(ABC) transporter
EXW36_06980	COG1131	(ABC) transporter
EXW36_06985	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW36_06990	COG1266	CAAX protease self-immunity
EXW36_07000	COG1522	sequence-specific DNA binding
EXW36_07010	COG1335	isochorismatase
EXW36_07020	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW36_07025	COG2070	2-Nitropropane dioxygenase
EXW36_07030	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW36_07035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW36_07040	COG1696	Membrane protein involved in D-alanine export
EXW36_07065	COG0716	FMN binding
EXW36_07100	COG0534	Mate efflux family protein
EXW36_07105	COG1968	undecaprenyl-diphosphatase activity
EXW36_07125	COG1846	Transcriptional regulator
EXW36_07135	COG1301	dicarboxylic acid transport
EXW36_07140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW36_07150	COG3874	Sporulation protein YtfJ
EXW36_07175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW36_07180	COG0028	Belongs to the TPP enzyme family
EXW36_07185	COG0440	acetolactate synthase activity
EXW36_07195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW36_07205	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW36_07215	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW36_07220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW36_07230	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW36_07235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW36_07240	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW36_07245	COG0107	imidazoleglycerol-phosphate synthase activity
EXW36_07255	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW36_07260	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW36_07275	COG1183	phosphatidylcholine synthase activity
EXW36_07280	COG1368	sulfuric ester hydrolase activity
EXW36_07290	COG0019	diaminopimelate decarboxylase activity
EXW36_07300	COG0175	sulfate reduction
EXW36_07305	COG2046	Belongs to the sulfate adenylyltransferase family
EXW36_07310	COG0529	Catalyzes the synthesis of activated sulfate
EXW36_07315	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW36_07335	COG1648	precorrin-2 dehydrogenase activity
EXW36_07340	COG0733	neurotransmitter:sodium symporter activity
EXW36_07365	COG1757	Na H antiporter
EXW36_07380	COG4758	membrane
EXW36_07385	COG4585	Histidine kinase
EXW36_07390	COG2197	response regulator
EXW36_07400	COG1114	Component of the transport system for branched-chain amino acids
EXW36_07410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW36_07450	COG0730	response to heat
EXW36_07455	COG0306	phosphate transporter
EXW36_07460	COG1392	Phosphate transport regulator
EXW36_07465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW36_07480	COG3852	Histidine kinase
EXW36_07485	COG1801	Protein of unknown function DUF72
EXW36_07495	COG0582	viral genome integration into host DNA
EXW36_07500	COG5002	protein histidine kinase activity
EXW36_07515	COG0392	lysyltransferase activity
EXW36_07515	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW36_07530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW36_07535	COG1686	Belongs to the peptidase S11 family
EXW36_07540	COG2715	membrane protein required for spore maturation
EXW36_07545	COG0700	Nucleoside recognition
EXW36_07550	COG1187	pseudouridine synthase activity
EXW36_07560	COG1333	cytochrome c biogenesis protein
EXW36_07565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW36_07570	COG0745	RESPONSE REGULATOR receiver
EXW36_07575	COG5002	protein histidine kinase activity
EXW36_07580	COG2096	Adenosyltransferase
EXW36_07585	COG4942	peptidase
EXW36_07595	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW36_07600	COG1141	Ferredoxin
EXW36_07605	COG4955	Helix-turn-helix domain
EXW36_07610	COG0514	ATP-dependent DNA helicase (RecQ)
EXW36_07615	COG1266	CAAX protease self-immunity
EXW36_07625	COG1408	metallophosphoesterase
EXW36_07640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW36_07660	COG0492	ferredoxin-NADP+ reductase activity
EXW36_07665	COG0252	asparaginase activity
EXW36_07675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW36_07685	COG1304	FMN binding
EXW36_07715	COG1160	GTP binding
EXW36_07720	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW36_07740	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW36_07750	COG0302	gtp cyclohydrolase
EXW36_07755	COG0142	geranyltranstransferase activity
EXW36_07760	COG2226	methyltransferase
EXW36_07765	COG0142	geranyltranstransferase activity
EXW36_07780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW36_07790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW36_07795	COG0457	Tetratricopeptide repeat
EXW36_07800	COG5582	Belongs to the UPF0302 family
EXW36_07815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW36_07830	COG4347	Protein of unknown function (DUF1405)
EXW36_07845	COG2738	Putative neutral zinc metallopeptidase
EXW36_07855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_07860	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW36_07865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW36_07870	COG1803	Methylglyoxal synthase
EXW36_07875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW36_07880	COG0438	transferase activity, transferring glycosyl groups
EXW36_07885	COG0617	tRNA 3'-terminal CCA addition
EXW36_07895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW36_07900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW36_07910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW36_07910	COG1199	ATP-dependent helicase activity
EXW36_07930	COG3935	DnaD domain protein
EXW36_07935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW36_07945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW36_07945	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW36_07950	COG3331	DNA recombination
EXW36_07985	COG4474	Belongs to the UPF0398 family
EXW36_07990	COG3599	regulation of cell shape
EXW36_08000	COG0116	Belongs to the methyltransferase superfamily
EXW36_08010	COG1199	ATP-dependent helicase activity
EXW36_08015	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW36_08025	COG0024	Methionine aminopeptidase
EXW36_08035	COG2233	PERMEase
EXW36_08040	COG2311	Membrane
EXW36_08050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW36_08060	COG0456	acetyltransferase
EXW36_08070	COG2897	thiosulfate sulfurtransferase activity
EXW36_08110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW36_08135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW36_08150	COG1215	transferase activity, transferring glycosyl groups
EXW36_08155	COG0438	transferase activity, transferring glycosyl groups
EXW36_08170	COG0454	-acetyltransferase
EXW36_08190	COG0328	RNA-DNA hybrid ribonuclease activity
EXW36_08225	COG3403	YqcI/YcgG family
EXW36_08230	COG1280	lysine exporter protein (LysE YggA)
EXW36_08245	COG3162	membrane
EXW36_08250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW36_08255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW36_08265	COG0475	glutathione-regulated potassium exporter activity
EXW36_08270	COG4978	Transcriptional regulator
EXW36_08270	COG0789	Transcriptional regulator
EXW36_08280	COG2323	membrane
EXW36_08285	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW36_08315	COG2814	Major facilitator Superfamily
EXW36_08335	COG1923	regulation of RNA biosynthetic process
EXW36_08360	COG0835	chemotaxis
EXW36_08360	COG0784	Response regulator, receiver
EXW36_08375	COG0697	spore germination
EXW36_08390	COG0861	Integral membrane protein TerC family
EXW36_08400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW36_08420	COG1776	CheC inhibitor of MCP methylation
EXW36_08420	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW36_08430	COG1338	Plays a role in the flagellum-specific transport system
EXW36_08435	COG1987	bacterial-type flagellum assembly
EXW36_08445	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW36_08450	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW36_08455	COG1419	protein localization to endoplasmic reticulum
EXW36_08460	COG4786	Flagellar basal body rod
EXW36_08465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW36_08495	COG0412	Dienelactone hydrolase
EXW36_08500	COG2329	Antibiotic biosynthesis monooxygenase
EXW36_08515	COG2814	Major facilitator Superfamily
EXW36_08525	COG0583	DNA-binding transcription factor activity
EXW36_08530	COG3842	ATPase activity
EXW36_08580	COG0406	alpha-ribazole phosphatase activity
EXW36_08610	COG0367	asparagine synthase
EXW36_08640	COG1802	Transcriptional regulator
EXW36_08645	COG0697	spore germination
EXW36_08655	COG0438	transferase activity, transferring glycosyl groups
EXW36_08655	COG1216	Glycosyl transferase, family 2
EXW36_08660	COG1757	Na H antiporter
EXW36_08690	COG0534	Mate efflux family protein
EXW36_08695	COG3340	Belongs to the peptidase S51 family
EXW36_08715	COG0785	Cytochrome C biogenesis protein
EXW36_08720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_08735	COG3048	D-serine ammonia-lyase activity
EXW36_08740	COG2733	membrane
EXW36_08775	COG1131	(ABC) transporter
EXW36_08790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW36_08825	COG0528	UMP kinase activity
EXW36_08835	COG1027	Aspartate ammonia-lyase
EXW36_08840	COG0281	malic enzyme
EXW36_08845	COG4191	Histidine kinase
EXW36_08850	COG0784	Response regulator, receiver
EXW36_08855	COG1846	Transcriptional regulator
EXW36_08865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW36_08875	COG2502	aspartate--ammonia ligase
EXW36_08910	COG1051	belongs to the nudix hydrolase family
EXW36_08915	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW36_08925	COG2814	Major facilitator Superfamily
EXW36_08955	COG0477	Major facilitator Superfamily
EXW36_08960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW36_08970	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW36_08975	COG2223	nitrite transmembrane transporter activity
EXW36_08980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW36_08995	COG2244	polysaccharide biosynthetic process
EXW36_09000	COG0733	neurotransmitter:sodium symporter activity
EXW36_09010	COG5566	PFAM Mor transcription activator
EXW36_09015	COG2323	membrane
EXW36_09030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW36_09040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW36_09045	COG0028	Belongs to the TPP enzyme family
EXW36_09060	COG0129	dihydroxy-acid dehydratase activity
EXW36_09065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW36_09090	COG2814	Major facilitator Superfamily
EXW36_09095	COG3384	dioxygenase
EXW36_09120	COG4166	transmembrane transport
EXW36_09125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_09135	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW36_09140	COG1054	Belongs to the UPF0176 family
EXW36_09150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW36_09155	COG0531	amino acid
EXW36_09190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW36_09205	COG4257	antibiotic catabolic process
EXW36_09210	COG2390	Transcriptional regulator
EXW36_09220	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW36_09225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_09230	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW36_09245	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW36_09260	COG0583	DNA-binding transcription factor activity
EXW36_09275	COG0006	proline dipeptidase activity
EXW36_09280	COG2132	Multicopper oxidase
EXW36_09290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW36_09310	COG1114	Component of the transport system for branched-chain amino acids
EXW36_09320	COG1276	copper resistance
EXW36_09320	COG2372	response to copper ion
EXW36_09325	COG4549	nuclear export factor GLE1
EXW36_09335	COG0697	spore germination
EXW36_09340	COG0583	DNA-binding transcription factor activity
EXW36_09345	COG1959	2 iron, 2 sulfur cluster binding
EXW36_09350	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW36_09355	COG0778	Nitroreductase
EXW36_09370	COG0628	permease
EXW36_09385	COG1231	oxidoreductase activity
EXW36_09390	COG0523	cobalamin synthesis protein
EXW36_09400	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_09405	COG2030	dehydratase
EXW36_09410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW36_09425	COG0411	ABC transporter
EXW36_09445	COG0583	DNA-binding transcription factor activity
EXW36_09455	COG1942	4-Oxalocrotonate Tautomerase
EXW36_09470	COG0346	lactoylglutathione lyase activity
EXW36_09480	COG1271	oxidase subunit
EXW36_09485	COG1294	oxidase, subunit
EXW36_09490	COG4988	ABC transporter
EXW36_09495	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW36_09525	COG1686	Belongs to the peptidase S11 family
EXW36_09540	COG1388	LysM domain
EXW36_09540	COG0791	NLP P60 protein
EXW36_09550	COG1132	(ABC) transporter
EXW36_09555	COG0745	RESPONSE REGULATOR receiver
EXW36_09560	COG5002	protein histidine kinase activity
EXW36_09565	COG0300	oxidoreductase activity
EXW36_09570	COG4122	O-methyltransferase activity
EXW36_09600	COG0460	homoserine dehydrogenase
EXW36_09610	COG0083	homoserine kinase activity
EXW36_09625	COG1316	TRANSCRIPTIONal
EXW36_09645	COG1285	pathogenesis
EXW36_09650	COG1247	-acetyltransferase
EXW36_09670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW36_09680	COG1082	Xylose isomerase domain protein TIM barrel
EXW36_09690	COG2814	Major facilitator Superfamily
EXW36_09695	COG1279	arginine transmembrane transporter activity
EXW36_09700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_09710	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW36_09740	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW36_09745	COG0577	efflux transmembrane transporter activity
EXW36_09750	COG2002	toxin-antitoxin pair type II binding
EXW36_09755	COG1404	Belongs to the peptidase S8 family
EXW36_09760	COG0640	Transcriptional regulator
EXW36_09765	COG0667	Aldo Keto reductase
EXW36_09810	COG3949	Membrane
EXW36_09815	COG0783	Belongs to the Dps family
EXW36_09830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW36_09840	COG1231	oxidoreductase activity
EXW36_09845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_09850	COG4989	oxidoreductase activity
EXW36_09855	COG0523	cobalamin synthesis protein
EXW36_09860	COG0456	acetyltransferase
EXW36_09865	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW36_09890	COG1136	(ABC) transporter
EXW36_09895	COG0577	efflux transmembrane transporter activity
EXW36_09900	COG0745	RESPONSE REGULATOR receiver
EXW36_09905	COG2205	protein histidine kinase activity
EXW36_09910	COG1902	pentaerythritol trinitrate reductase activity
EXW36_09915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW36_09925	COG4166	transmembrane transport
EXW36_09930	COG0346	lactoylglutathione lyase activity
EXW36_09940	COG0406	alpha-ribazole phosphatase activity
EXW36_09950	COG5337	Spore coat protein CotH
EXW36_09955	COG1051	belongs to the nudix hydrolase family
EXW36_09960	COG0586	Pfam SNARE associated Golgi protein
EXW36_09965	COG2244	polysaccharide biosynthetic process
EXW36_09975	COG0701	Predicted permease
EXW36_09980	COG3689	TIGRFAM TIGR03943 family protein
EXW36_09985	COG1607	acyl-coa hydrolase
EXW36_09995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW36_10010	COG0702	epimerase
EXW36_10015	COG2839	Protein conserved in bacteria
EXW36_10020	COG1253	flavin adenine dinucleotide binding
EXW36_10045	COG1114	Component of the transport system for branched-chain amino acids
EXW36_10050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW36_10065	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW36_10075	COG1876	peptidase activity
EXW36_10080	COG0494	nUDIX hydrolase
EXW36_10090	COG2211	Major facilitator Superfamily
EXW36_10105	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW36_10115	COG0561	phosphatase activity
EXW36_10120	COG1846	Transcriptional regulator
EXW36_10125	COG2814	Major facilitator Superfamily
EXW36_10135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW36_10150	COG1819	glycosyl
EXW36_10155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_10160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_10185	COG0456	acetyltransferase
EXW36_10205	COG3874	Sporulation protein YtfJ
EXW36_10230	COG2226	methyltransferase
EXW36_10260	COG0604	alcohol dehydrogenase
EXW36_10265	COG1595	DNA-templated transcription, initiation
EXW36_10290	COG0426	domain, Protein
EXW36_10290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW36_10300	COG0386	Belongs to the glutathione peroxidase family
EXW36_10305	COG1305	Transglutaminase-like
EXW36_10310	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW36_10315	COG0714	Associated with various cellular activities
EXW36_10330	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW36_10335	COG1140	nitrate reductase beta subunit
EXW36_10340	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW36_10345	COG2181	nitrate reductase activity
EXW36_10350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW36_10355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW36_10360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW36_10365	COG0303	'Molybdopterin
EXW36_10370	COG0314	molybdopterin synthase activity
EXW36_10380	COG2223	nitrite transmembrane transporter activity
EXW36_10405	COG1648	precorrin-2 dehydrogenase activity
EXW36_10415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW36_10415	COG1587	Uroporphyrinogen-III synthase
EXW36_10420	COG2146	nitrite reductase [NAD(P)H] activity
EXW36_10425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW36_10440	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW36_10470	COG2359	stage V sporulation protein S
EXW36_10480	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW36_10490	COG5444	nuclease activity
EXW36_10500	COG1418	mRNA catabolic process
EXW36_10505	COG0488	(ABC) transporter
EXW36_10540	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EXW36_10555	COG0515	serine threonine protein kinase
EXW36_10555	COG2815	serine threonine protein kinase
EXW36_10565	COG1413	lyase activity
EXW36_10580	COG2136	Putative SAM-dependent methyltransferase
EXW36_10580	COG2521	methyltransferase
EXW36_10585	COG0018	arginyl-trna synthetase
EXW36_10635	COG0017	Asparaginyl-tRNA synthetase
EXW36_10640	COG0733	neurotransmitter:sodium symporter activity
EXW36_10665	COG2610	gluconate transmembrane transporter activity
EXW36_10675	COG1794	racemase activity, acting on amino acids and derivatives
EXW36_10685	COG0456	acetyltransferase
EXW36_10690	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW36_10700	COG1131	(ABC) transporter
EXW36_10705	COG4473	ABC transporter
EXW36_10715	COG0546	phosphoglycolate phosphatase activity
EXW36_10730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW36_10745	COG0768	penicillin binding
EXW36_10755	COG0204	Acyl-transferase
EXW36_10760	COG1272	protein, Hemolysin III
EXW36_10765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW36_10770	COG0805	protein transport
EXW36_10790	COG1999	signal sequence binding
EXW36_10795	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW36_10800	COG0367	asparagine synthase
EXW36_10815	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW36_10820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_10825	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW36_10845	COG1335	isochorismatase
EXW36_10855	COG0668	transmembrane transport
EXW36_10860	COG2203	Gaf domain
EXW36_10860	COG4585	Histidine kinase
EXW36_10865	COG2197	response regulator
EXW36_10870	COG1737	Transcriptional regulator
EXW36_10875	COG1064	alcohol dehydrogenase
EXW36_10890	COG1070	Carbohydrate kinase
EXW36_10900	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW36_10920	COG1125	glycine betaine transport
EXW36_10920	COG0517	IMP dehydrogenase activity
EXW36_10925	COG1174	glycine betaine transport
EXW36_10960	COG1253	flavin adenine dinucleotide binding
EXW36_10965	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_10970	COG5506	Protein of unknown function (DUF1694)
EXW36_10985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW36_10990	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW36_10995	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW36_11000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW36_11005	COG0456	acetyltransferase
EXW36_11010	COG3829	transcription factor binding
EXW36_11015	COG1509	lysine 2,3-aminomutase activity
EXW36_11025	COG4479	Belongs to the UPF0346 family
EXW36_11050	COG0515	serine threonine protein kinase
EXW36_11050	COG4991	sh3 domain protein
EXW36_11050	COG3064	Membrane
EXW36_11060	COG0671	phosphoesterase, PA-phosphatase related
EXW36_11065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW36_11070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_11125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW36_11150	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_11170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW36_11170	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW36_11180	COG2814	Major facilitator Superfamily
EXW36_11190	COG0372	Belongs to the citrate synthase family
EXW36_11195	COG2079	MmgE PrpD family protein
EXW36_11200	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW36_11205	COG1960	acyl-CoA dehydrogenase activity
EXW36_11210	COG2084	Dehydrogenase
EXW36_11215	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_11220	COG1280	lysine exporter protein (LysE YggA)
EXW36_11225	COG1024	Enoyl-CoA hydratase
EXW36_11240	COG0420	3'-5' exonuclease activity
EXW36_11265	COG2223	nitrite transmembrane transporter activity
EXW36_11270	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_11275	COG1169	isochorismate synthase
EXW36_11280	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW36_11285	COG3433	isochorismatase activity
EXW36_11285	COG1535	isochorismatase
EXW36_11290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW36_11295	COG3251	PFAM MbtH domain protein
EXW36_11300	COG2814	Major facilitator Superfamily
EXW36_11315	COG0776	regulation of translation
EXW36_11325	COG2318	DinB family
EXW36_11330	COG1115	amino acid carrier protein
EXW36_11345	COG2329	Antibiotic biosynthesis monooxygenase
EXW36_11355	COG1187	pseudouridine synthase activity
EXW36_11360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW36_11365	COG3655	Transcriptional regulator
EXW36_11375	COG1136	(ABC) transporter
EXW36_11385	COG0596	Alpha beta hydrolase
EXW36_11400	COG0028	Belongs to the TPP enzyme family
EXW36_11410	COG2226	methyltransferase
EXW36_11420	COG1253	flavin adenine dinucleotide binding
EXW36_11450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW36_11470	COG1846	Transcriptional regulator
EXW36_11480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_11485	COG1309	transcriptional regulator
EXW36_11515	COG1247	-acetyltransferase
EXW36_11545	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW36_11555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_11755	COG2002	toxin-antitoxin pair type II binding
EXW36_11785	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW36_11930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW36_11995	COG0561	phosphatase activity
EXW36_12005	COG0583	DNA-binding transcription factor activity
EXW36_12010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW36_12020	COG0583	DNA-binding transcription factor activity
EXW36_12025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW36_12030	COG2258	MOSC domain
EXW36_12045	COG1132	(ABC) transporter
EXW36_12050	COG1132	(ABC) transporter
EXW36_12065	COG0189	ligase activity
EXW36_12090	COG1396	sequence-specific DNA binding
EXW36_12125	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW36_12130	COG1595	DNA-templated transcription, initiation
EXW36_12155	COG1649	PFAM Uncharacterised BCR, COG1649
EXW36_12175	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW36_12180	COG2971	BadF BadG BcrA BcrD
EXW36_12190	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW36_12230	COG1309	transcriptional regulator
EXW36_12245	COG1136	(ABC) transporter
EXW36_12250	COG3615	Tellurite resistance protein tehB
EXW36_12250	COG0500	methyltransferase
EXW36_12260	COG0693	protein deglycase activity
EXW36_12270	COG0588	phosphoglycerate mutase activity
EXW36_12295	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW36_12305	COG0110	maltose O-acetyltransferase activity
EXW36_12310	COG1136	(ABC) transporter
EXW36_12335	COG1686	Belongs to the peptidase S11 family
EXW36_12360	COG0768	penicillin binding
EXW36_12365	COG0745	RESPONSE REGULATOR receiver
EXW36_12370	COG2205	protein histidine kinase activity
EXW36_12375	COG1136	(ABC) transporter
EXW36_12380	COG0577	efflux transmembrane transporter activity
EXW36_12390	COG1595	DNA-templated transcription, initiation
EXW36_12400	COG0768	penicillin binding
EXW36_12405	COG0768	penicillin binding
EXW36_12440	COG1252	NADH dehydrogenase
EXW36_12445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW36_12445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_12460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW36_12460	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW36_12480	COG1136	(ABC) transporter
EXW36_12485	COG0577	efflux transmembrane transporter activity
EXW36_12505	COG1136	(ABC) transporter
EXW36_12525	COG2723	6-phospho-beta-galactosidase activity
EXW36_12600	COG1114	Component of the transport system for branched-chain amino acids
EXW36_12610	COG2239	Acts as a magnesium transporter
EXW36_12625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW36_12640	COG0697	spore germination
EXW36_12665	COG3397	chitin binding
EXW36_12670	COG0823	Involved in the tonB-independent uptake of proteins
EXW36_12680	COG1408	metallophosphoesterase
EXW36_12690	COG1131	(ABC) transporter
EXW36_12700	COG1309	transcriptional regulator
EXW36_12710	COG1960	acyl-CoA dehydrogenase activity
EXW36_12715	COG0439	Biotin carboxylase
EXW36_12720	COG0511	ligase activity, forming carbon-carbon bonds
EXW36_12725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW36_12730	COG1024	Enoyl-CoA hydratase
EXW36_12735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW36_12740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW36_12785	COG0572	uridine kinase
EXW36_12790	COG2318	DinB family
EXW36_12820	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW36_12850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW36_12875	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_12880	COG1733	regulation of RNA biosynthetic process
EXW36_12905	COG1309	transcriptional regulator
EXW36_12920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW36_12935	COG0697	spore germination
EXW36_12940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_12970	COG2323	membrane
EXW36_12985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_12990	COG0697	spore germination
EXW36_13010	COG0201	protein transport
EXW36_13020	COG0737	Belongs to the 5'-nucleotidase family
EXW36_13025	COG3227	Zinc metalloprotease (Elastase)
EXW36_13030	COG1523	belongs to the glycosyl hydrolase 13 family
EXW36_13045	COG0076	glutamate decarboxylase activity
EXW36_13050	COG0657	acetylesterase activity
EXW36_13055	COG1073	alpha beta
EXW36_13065	COG0577	efflux transmembrane transporter activity
EXW36_13070	COG1136	(ABC) transporter
EXW36_13100	COG5002	protein histidine kinase activity
EXW36_13105	COG0745	RESPONSE REGULATOR receiver
EXW36_13110	COG1011	Hydrolase
EXW36_13130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW36_13135	COG1183	phosphatidylcholine synthase activity
EXW36_13145	COG1132	(ABC) transporter
EXW36_13155	COG3961	Belongs to the TPP enzyme family
EXW36_13175	COG0322	excinuclease ABC activity
EXW36_13200	COG2318	DinB family
EXW36_13215	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW36_13240	COG3878	Protein conserved in bacteria
EXW36_13265	COG1051	belongs to the nudix hydrolase family
EXW36_13270	COG0592	DNA-directed DNA polymerase activity
EXW36_13275	COG2816	NAD+ diphosphatase activity
EXW36_13285	COG2223	nitrite transmembrane transporter activity
EXW36_13295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW36_13305	COG0494	nUDIX hydrolase
EXW36_13325	COG0697	spore germination
EXW36_13330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_13340	COG0584	glycerophosphoryl diester phosphodiesterase
EXW36_13355	COG2814	Major facilitator Superfamily
EXW36_13395	COG0768	penicillin binding
EXW36_13400	COG0671	phosphoesterase, PA-phosphatase related
EXW36_13405	COG0604	alcohol dehydrogenase
EXW36_13410	COG5002	protein histidine kinase activity
EXW36_13415	COG0745	RESPONSE REGULATOR receiver
EXW36_13425	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW36_13435	COG2205	protein histidine kinase activity
EXW36_13450	COG1122	ATPase activity
EXW36_13455	COG4720	Psort location CytoplasmicMembrane, score
EXW36_13460	COG1794	racemase activity, acting on amino acids and derivatives
EXW36_13465	COG1819	glycosyl
EXW36_13475	COG0768	penicillin binding
EXW36_13480	COG5002	protein histidine kinase activity
EXW36_13485	COG0561	phosphatase activity
EXW36_13530	COG2124	cytochrome p450
EXW36_13575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW36_13585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_13590	COG0460	homoserine dehydrogenase
EXW36_13610	COG0577	efflux transmembrane transporter activity
EXW36_13615	COG1136	(ABC) transporter
EXW36_13625	COG0488	(ABC) transporter
EXW36_13630	COG0667	Aldo Keto reductase
EXW36_13635	COG0583	DNA-binding transcription factor activity
EXW36_13640	COG2205	protein histidine kinase activity
EXW36_13645	COG0745	RESPONSE REGULATOR receiver
EXW36_13655	COG3773	Cell wall hydrolase
EXW36_13660	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW36_13670	COG3386	PFAM SMP-30 Gluconolaconase
EXW36_13710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_13725	COG2959	enzyme of heme biosynthesis
EXW36_13750	COG3483	tryptophan 2,3-dioxygenase activity
EXW36_13755	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW36_13760	COG3844	kynureninase activity
EXW36_13765	COG1309	transcriptional regulator
EXW36_13780	COG3284	Transcriptional regulator
EXW36_13795	COG1349	DNA-binding transcription factor activity
EXW36_13825	COG1959	2 iron, 2 sulfur cluster binding
EXW36_13840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW36_13845	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW36_13850	COG0022	dehydrogenase e1 component
EXW36_13855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW36_13875	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_13880	COG0456	acetyltransferase
EXW36_13880	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW36_13910	COG4176	ABC-type proline glycine betaine transport system permease component
EXW36_13915	COG4175	Glycine betaine
EXW36_13915	COG0517	IMP dehydrogenase activity
EXW36_13940	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW36_13945	COG2153	protein acetylation
EXW36_13950	COG3397	chitin binding
EXW36_13960	COG1819	glycosyl
EXW36_13975	COG2205	protein histidine kinase activity
EXW36_13980	COG2315	Protein conserved in bacteria
EXW36_14025	COG3973	AAA domain
EXW36_14035	COG2105	PFAM AIG2 family protein
EXW36_14040	COG0514	ATP-dependent DNA helicase (RecQ)
EXW36_14065	COG4637	Psort location Cytoplasmic, score
EXW36_14075	COG1227	inorganic diphosphatase activity
EXW36_14080	COG3397	chitin binding
EXW36_14085	COG2318	DinB family
EXW36_14105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW36_14110	COG1115	amino acid carrier protein
EXW36_14115	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_14120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW36_14130	COG3938	Belongs to the proline racemase family
EXW36_14135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW36_14175	COG0586	Pfam SNARE associated Golgi protein
EXW36_14190	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW36_14195	COG4166	transmembrane transport
EXW36_14205	COG4948	Mandelate Racemase Muconate Lactonizing
EXW36_14225	COG0667	Aldo Keto reductase
EXW36_14265	COG2936	dipeptidyl-peptidase activity
EXW36_14275	COG0745	RESPONSE REGULATOR receiver
EXW36_14305	COG1164	Oligoendopeptidase f
EXW36_14310	COG0531	amino acid
EXW36_14315	COG1522	sequence-specific DNA binding
EXW36_14330	COG1307	EDD domain protein, DegV family
EXW36_14355	COG1335	isochorismatase
EXW36_14370	COG2814	Major facilitator Superfamily
EXW36_14380	COG1664	Polymer-forming cytoskeletal
EXW36_14385	COG0789	Transcriptional regulator
EXW36_14390	COG4533	DNA binding
EXW36_14395	COG2814	Major facilitator Superfamily
EXW36_14395	COG0477	Major facilitator Superfamily
EXW36_14415	COG2261	transglycosylase associated protein
EXW36_14430	COG2226	methyltransferase
EXW36_14465	COG0436	Aminotransferase
EXW36_14470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW36_14495	COG1131	(ABC) transporter
EXW36_14500	COG2188	Transcriptional regulator
EXW36_14545	COG0628	permease
EXW36_14590	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW36_14600	COG0697	spore germination
EXW36_14605	COG2318	DinB family
EXW36_14655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW36_14665	COG2814	Major facilitator Superfamily
EXW36_14670	COG1368	sulfuric ester hydrolase activity
EXW36_14685	COG0488	(ABC) transporter
EXW36_14690	COG1033	growth of symbiont in host cell
EXW36_14690	COG2409	Drug exporters of the RND superfamily
EXW36_14695	COG1309	transcriptional regulator
EXW36_14700	COG0494	nUDIX hydrolase
EXW36_14720	COG0287	Prephenate dehydrogenase
EXW36_14735	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW36_14735	COG1605	Chorismate mutase
EXW36_14770	COG1388	LysM domain
EXW36_14770	COG3584	3D domain protein
EXW36_14780	COG0346	lactoylglutathione lyase activity
EXW36_14790	COG0431	NADPH-dependent FMN reductase
EXW36_14820	COG0579	oxidoreductase
EXW36_14825	COG1879	ABC-type sugar transport system periplasmic component
EXW36_14840	COG1129	ABC transporter
EXW36_14845	COG2390	Transcriptional regulator
EXW36_14865	COG2226	methyltransferase
EXW36_14885	COG2329	Antibiotic biosynthesis monooxygenase
EXW36_14910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_14915	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW36_14920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW36_14925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW36_14930	COG3239	Fatty acid desaturase
EXW36_14955	COG3842	ATPase activity
EXW36_14980	COG1175	transmembrane transport
EXW36_14985	COG1349	DNA-binding transcription factor activity
EXW36_14995	COG3655	Transcriptional regulator
EXW36_15020	COG3279	Response regulator of the LytR AlgR family
EXW36_15035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_15040	COG0346	lactoylglutathione lyase activity
EXW36_15065	COG0714	Associated with various cellular activities
EXW36_15085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW36_15090	COG0753	catalase activity
EXW36_15100	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW36_15125	COG0714	Associated with various cellular activities
EXW36_15135	COG0778	Nitroreductase
EXW36_15140	COG1846	Transcriptional regulator
EXW36_15155	COG0494	nUDIX hydrolase
EXW36_15175	COG1725	Transcriptional regulator
EXW36_15205	COG2207	Transcriptional regulator
EXW36_15210	COG0456	acetyltransferase
EXW36_15225	COG0697	spore germination
EXW36_15230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_15235	COG1671	Belongs to the UPF0178 family
EXW36_15255	COG0814	amino acid
EXW36_15260	COG0697	spore germination
EXW36_15275	COG0642	Histidine kinase
EXW36_15280	COG0745	RESPONSE REGULATOR receiver
EXW36_15285	COG0596	Alpha beta hydrolase
EXW36_15295	COG0456	acetyltransferase
EXW36_15295	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW36_15320	COG0730	response to heat
EXW36_15330	COG0833	amino acid
EXW36_15340	COG4335	DNA alkylation repair
EXW36_15365	COG0681	Belongs to the peptidase S26 family
EXW36_15370	COG0768	penicillin binding
EXW36_15385	COG3104	oligopeptide transport
EXW36_15390	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW36_15405	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW36_15410	COG1984	allophanate hydrolase subunit 2
EXW36_15415	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW36_15420	COG1414	Transcriptional regulator
EXW36_15435	COG1960	acyl-CoA dehydrogenase activity
EXW36_15460	COG0640	Transcriptional regulator
EXW36_15470	COG3314	Sporulation integral membrane protein YlbJ
EXW36_15490	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW36_15495	COG0577	efflux transmembrane transporter activity
EXW36_15500	COG0577	efflux transmembrane transporter activity
EXW36_15505	COG1136	(ABC) transporter
EXW36_15540	COG3848	Pyruvate phosphate dikinase
EXW36_15540	COG0574	Belongs to the PEP-utilizing enzyme family
EXW36_15550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW36_15575	COG5002	protein histidine kinase activity
EXW36_15580	COG0745	RESPONSE REGULATOR receiver
EXW36_15590	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW36_15610	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW36_15615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW36_15620	COG1121	(ABC) transporter
EXW36_15640	COG0798	PFAM Bile acid sodium symporter
EXW36_15645	COG0346	lactoylglutathione lyase activity
EXW36_15650	COG0640	Transcriptional regulator
EXW36_15665	COG1309	transcriptional regulator
EXW36_15670	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_15675	COG1522	sequence-specific DNA binding
EXW36_15690	COG0346	lactoylglutathione lyase activity
EXW36_15720	COG0745	RESPONSE REGULATOR receiver
EXW36_15725	COG3850	Histidine kinase
EXW36_15725	COG5002	protein histidine kinase activity
EXW36_15755	COG1073	alpha beta
EXW36_15760	COG0814	amino acid
EXW36_15765	COG1760	l-serine dehydratase
EXW36_15770	COG1760	l-serine dehydratase
EXW36_15780	COG5002	protein histidine kinase activity
EXW36_15785	COG0745	RESPONSE REGULATOR receiver
EXW36_15795	COG5002	protein histidine kinase activity
EXW36_15820	COG4977	sequence-specific DNA binding
EXW36_15860	COG2814	Major facilitator Superfamily
EXW36_15875	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW36_15900	COG1522	sequence-specific DNA binding
EXW36_15910	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW36_15925	COG1136	(ABC) transporter
EXW36_15930	COG0577	efflux transmembrane transporter activity
EXW36_15950	COG5002	protein histidine kinase activity
EXW36_15950	COG3850	Histidine kinase
EXW36_15960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_15990	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW36_16010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW36_16045	COG2814	Major facilitator Superfamily
EXW36_16130	COG2849	repeat protein
EXW36_16230	COG0477	Major facilitator Superfamily
EXW36_16245	COG1846	Transcriptional regulator
EXW36_16250	COG2814	Major facilitator Superfamily
EXW36_16270	COG0640	Transcriptional regulator
EXW36_16295	COG1329	Transcriptional regulator
EXW36_16350	COG5002	protein histidine kinase activity
EXW36_16365	COG1136	(ABC) transporter
EXW36_16380	COG1131	(ABC) transporter
EXW36_16455	COG0789	Transcriptional regulator
EXW36_16515	COG4187	Peptidase family M20/M25/M40
EXW36_16530	COG2031	fatty acid transporter
EXW36_16540	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW36_16590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW36_16595	COG1288	antiporter activity
EXW36_16600	COG2356	endonuclease I
EXW36_16605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW36_16625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW36_16645	COG1785	Belongs to the alkaline phosphatase family
EXW36_16650	COG0778	Nitroreductase
EXW36_16655	COG1733	regulation of RNA biosynthetic process
EXW36_16675	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_16685	COG1131	(ABC) transporter
EXW36_16715	COG1595	DNA-templated transcription, initiation
EXW36_16730	COG1011	Hydrolase
EXW36_16735	COG2365	Tyrosine phosphatase family
EXW36_16760	COG0346	lactoylglutathione lyase activity
EXW36_16765	COG1940	carbohydrate kinase activity
EXW36_16770	COG0738	Major facilitator superfamily
EXW36_16775	COG0110	maltose O-acetyltransferase activity
EXW36_16790	COG0628	permease
EXW36_16795	COG2261	transglycosylase associated protein
EXW36_16810	COG1720	tRNA m6t6A37 methyltransferase activity
EXW36_16830	COG0477	Major facilitator Superfamily
EXW36_16845	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW36_16855	COG1253	flavin adenine dinucleotide binding
EXW36_16860	COG0789	Transcriptional regulator
EXW36_16870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW36_16905	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW36_16910	COG3813	Protein conserved in bacteria
EXW36_16915	COG2706	6-phosphogluconolactonase activity
EXW36_16920	COG1070	Carbohydrate kinase
EXW36_16930	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW36_16935	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW36_16950	COG0814	amino acid
EXW36_16975	COG1151	hydroxylamine reductase activity
EXW36_17005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW36_17015	COG2072	flavoprotein involved in K transport
EXW36_17060	COG1695	Transcriptional regulator
EXW36_17065	COG0604	alcohol dehydrogenase
EXW36_17070	COG1113	amino acid transport
EXW36_17080	COG2814	Major facilitator Superfamily
EXW36_17090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW36_17095	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_17105	COG0534	Mate efflux family protein
EXW36_17110	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_17115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW36_17130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW36_17135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW36_17155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_17160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_17165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_17190	COG0583	DNA-binding transcription factor activity
EXW36_17215	COG1193	negative regulation of DNA recombination
EXW36_17225	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW36_17230	COG1164	Oligoendopeptidase f
EXW36_17235	COG2957	Belongs to the agmatine deiminase family
EXW36_17255	COG3781	membrane
EXW36_17270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW36_17305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW36_17310	COG0640	Transcriptional regulator
EXW36_17315	COG0604	alcohol dehydrogenase
EXW36_17320	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW36_17335	COG2808	Putative FMN-binding domain
EXW36_17340	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW36_17350	COG0277	FAD linked oxidase domain protein
EXW36_17370	COG1285	pathogenesis
EXW36_17380	COG2514	catechol 2,3-dioxygenase activity
EXW36_17385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW36_17390	COG1126	abc transporter atp-binding protein
EXW36_17395	COG0765	amino acid transport
EXW36_17400	COG2720	vancomycin resistance protein
EXW36_17425	COG1278	Cold shock
EXW36_17435	COG0716	FMN binding
EXW36_17445	COG0494	nUDIX hydrolase
EXW36_17465	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_17475	COG0165	Argininosuccinate lyase
EXW36_17490	COG4145	pantothenate transmembrane transporter activity
EXW36_17500	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_17505	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_17515	COG1657	PFAM Prenyltransferase squalene oxidase
EXW36_17520	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW36_17525	COG2962	Rard protein
EXW36_17530	COG3326	Membrane
EXW36_17535	COG0531	amino acid
EXW36_17570	COG2226	methyltransferase
EXW36_17575	COG4166	transmembrane transport
EXW36_17580	COG4166	transmembrane transport
EXW36_17585	COG4166	transmembrane transport
EXW36_17590	COG1316	TRANSCRIPTIONal
EXW36_17600	COG1595	DNA-templated transcription, initiation
EXW36_17610	COG1131	(ABC) transporter
EXW36_17630	COG0673	inositol 2-dehydrogenase activity
EXW36_17635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW36_17640	COG0187	DNA topoisomerase II activity
EXW36_17645	COG1832	CoA-binding protein
EXW36_17650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW36_17655	COG0745	RESPONSE REGULATOR receiver
EXW36_17665	COG1328	CTP reductase activity
EXW36_17675	COG4841	protein insertion into membrane
EXW36_17680	COG0824	Thioesterase
EXW36_17705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_17725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW36_17755	COG2211	Major facilitator Superfamily
EXW36_17765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW36_17780	COG0183	Belongs to the thiolase family
EXW36_17785	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_17790	COG1268	BioY protein
EXW36_17795	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_17800	COG1396	sequence-specific DNA binding
EXW36_17820	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EXW36_17840	COG0830	nickel cation binding
EXW36_17880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_17890	COG5002	protein histidine kinase activity
EXW36_17900	COG0400	carboxylic ester hydrolase activity
EXW36_17905	COG0346	lactoylglutathione lyase activity
EXW36_17910	COG0069	glutamate synthase activity
EXW36_17915	COG1902	pentaerythritol trinitrate reductase activity
EXW36_17925	COG1329	Transcriptional regulator
EXW36_17930	COG0010	Belongs to the arginase family
EXW36_17940	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW36_17945	COG2986	histidine ammonia-lyase
EXW36_17955	COG2226	methyltransferase
EXW36_17980	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW36_17985	COG0785	Cytochrome C biogenesis protein
EXW36_18000	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW36_18005	COG1131	(ABC) transporter
EXW36_18015	COG0583	DNA-binding transcription factor activity
EXW36_18025	COG1346	cytolysis
EXW36_18040	COG0730	response to heat
EXW36_18050	COG3409	Peptidoglycan-binding domain 1 protein
EXW36_18050	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW36_18070	COG1132	(ABC) transporter
EXW36_18075	COG1132	(ABC) transporter
EXW36_18080	COG3763	UPF0154 protein
EXW36_18100	COG3639	organic phosphonate transmembrane transporter activity
EXW36_18110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW36_18115	COG0737	Belongs to the 5'-nucleotidase family
EXW36_18125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW36_18130	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW36_18145	COG1695	Transcriptional regulator
EXW36_18150	COG0174	glutamine synthetase
EXW36_18155	COG0789	Transcriptional regulator
EXW36_18160	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW36_18165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW36_18170	COG2860	membrane
EXW36_18180	COG0464	growth
EXW36_18200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW36_18210	COG3584	3D domain protein
EXW36_18210	COG1388	LysM domain
EXW36_18215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW36_18215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW36_18215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW36_18220	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW36_18225	COG1349	DNA-binding transcription factor activity
EXW36_18230	COG1979	alcohol dehydrogenase
EXW36_18235	COG2322	membrane
EXW36_18245	COG1113	amino acid transport
EXW36_18260	COG1408	metallophosphoesterase
EXW36_18265	COG2116	formate transmembrane transporter activity
EXW36_18280	COG2217	Heavy metal translocating P-type atpase
EXW36_18285	COG2608	mercury ion transmembrane transporter activity
EXW36_18290	COG1937	Protein conserved in bacteria
EXW36_18320	COG4566	intracellular signal transduction
EXW36_18325	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW36_18330	COG2819	hydrolase of the alpha beta superfamily
EXW36_18335	COG1120	ATPase activity
EXW36_18340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_18345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_18350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_18355	COG0708	Exodeoxyribonuclease III
EXW36_18360	COG2169	Transcriptional regulator
EXW36_18365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW36_18370	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW36_18375	COG2706	6-phosphogluconolactonase activity
EXW36_18380	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW36_18385	COG2364	Membrane
EXW36_18395	COG0346	lactoylglutathione lyase activity
EXW36_18400	COG5001	Diguanylate cyclase
EXW36_18400	COG3300	MHYT domain
EXW36_18440	COG1346	cytolysis
EXW36_18450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_18455	COG0596	Alpha beta hydrolase
EXW36_18455	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW36_18460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW36_18470	COG2188	Transcriptional regulator
EXW36_18475	COG2723	6-phospho-beta-galactosidase activity
EXW36_18480	COG0823	Involved in the tonB-independent uptake of proteins
EXW36_18485	COG3773	Cell wall hydrolase
EXW36_18500	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW36_18510	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW36_18515	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW36_18520	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW36_18530	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW36_18535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW36_18540	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW36_18545	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW36_18545	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW36_18555	COG2359	stage V sporulation protein S
EXW36_18560	COG1692	metallophosphoesterase
EXW36_18565	COG1418	mRNA catabolic process
EXW36_18570	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW36_18575	COG1058	Belongs to the CinA family
EXW36_18575	COG1546	Belongs to the CinA family
EXW36_18580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW36_18585	COG1426	Protein conserved in bacteria
EXW36_18600	COG0300	oxidoreductase activity
EXW36_18605	COG0612	Peptidase, M16
EXW36_18610	COG0612	Peptidase, M16
EXW36_18615	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW36_18620	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW36_18625	COG3845	ABC transporter
EXW36_18630	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW36_18635	COG2188	Transcriptional regulator
EXW36_18645	COG1674	ftsk spoiiie
EXW36_18655	COG0740	serine-type endopeptidase activity
EXW36_18660	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW36_18670	COG0527	aspartate kinase activity
EXW36_18675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW36_18680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW36_18685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW36_18690	COG1873	PFAM PRC-barrel domain
EXW36_18695	COG0612	Peptidase, M16
EXW36_18700	COG0726	polysaccharide deacetylase
EXW36_18705	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW36_18715	COG0196	riboflavin kinase activity
EXW36_18725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW36_18730	COG1550	Protein conserved in bacteria
EXW36_18735	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW36_18740	COG1358	cellular component organization or biogenesis
EXW36_18745	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW36_18750	COG0195	Participates in both transcription termination and antitermination
EXW36_18755	COG0779	Required for maturation of 30S ribosomal subunits
EXW36_18765	COG0442	prolyl-tRNA aminoacylation
EXW36_18770	COG0750	zinc metalloprotease
EXW36_18780	COG4589	Belongs to the CDS family
EXW36_18790	COG0233	cytoplasmic translational termination
EXW36_18795	COG0528	UMP kinase activity
EXW36_18800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW36_18810	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW36_18815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW36_18820	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW36_18825	COG4974	Belongs to the 'phage' integrase family
EXW36_18830	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW36_18835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW36_18840	COG0758	DNA mediated transformation
EXW36_18845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW36_18850	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW36_18855	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW36_18870	COG0335	large ribosomal subunit rRNA binding
EXW36_18875	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW36_18880	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW36_18885	COG1837	Belongs to the UPF0109 family
EXW36_18895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW36_18905	COG0552	protein localization to endoplasmic reticulum
EXW36_18910	COG1196	nuclear chromosome segregation
EXW36_18915	COG0571	ribonuclease III activity
EXW36_18920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW36_18925	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_18930	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW36_18935	COG0416	fatty acid biosynthetic process
EXW36_18940	COG2050	protein possibly involved in aromatic compounds catabolism
EXW36_18940	COG1349	DNA-binding transcription factor activity
EXW36_18945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW36_18950	COG1461	Dihydroxyacetone kinase
EXW36_18955	COG1302	Protein conserved in bacteria
EXW36_18970	COG1564	THIamine pyrophosphokinase
EXW36_18975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW36_18985	COG0515	serine threonine protein kinase
EXW36_18985	COG2815	serine threonine protein kinase
EXW36_18990	COG0631	protein serine/threonine phosphatase activity
EXW36_18995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW36_19000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW36_19000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW36_19005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW36_19010	COG0242	peptide deformylase activity
EXW36_19015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW36_19020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW36_19025	COG1758	RNA polymerase activity
EXW36_19040	COG1561	YicC-like family, N-terminal region
EXW36_19045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW36_19055	COG0006	proline dipeptidase activity
EXW36_19075	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW36_19100	COG0167	dihydroorotate dehydrogenase activity
EXW36_19105	COG0543	2 iron, 2 sulfur cluster binding
EXW36_19110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW36_19120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW36_19125	COG0540	Belongs to the ATCase OTCase family
EXW36_19135	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW36_19140	COG0564	pseudouridine synthase activity
EXW36_19145	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW36_19155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW36_19160	COG3599	regulation of cell shape
EXW36_19165	COG2302	S4 RNA-binding domain
EXW36_19170	COG0762	integral membrane protein
EXW36_19175	COG1799	cell septum assembly
EXW36_19180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW36_19190	COG1873	PFAM PRC-barrel domain
EXW36_19195	COG1191	sigma factor activity
EXW36_19200	COG1191	sigma factor activity
EXW36_19210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW36_19215	COG0849	cell division
EXW36_19220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW36_19235	COG0772	Belongs to the SEDS family
EXW36_19240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW36_19245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW36_19250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW36_19255	COG0768	penicillin binding
EXW36_19260	COG0768	penicillin binding
EXW36_19270	COG0275	rRNA processing
EXW36_19275	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW36_19280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW36_19285	COG0454	-acetyltransferase
EXW36_19295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW36_19300	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW36_19305	COG1323	Belongs to the UPF0348 family
EXW36_19310	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW36_19315	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW36_19320	COG3314	Sporulation integral membrane protein YlbJ
EXW36_19330	COG0742	ribosomal rna small subunit methyltransferase
EXW36_19340	COG4471	UPF0298 protein
EXW36_19345	COG3679	Belongs to the UPF0342 family
EXW36_19350	COG0406	alpha-ribazole phosphatase activity
EXW36_19365	COG2340	Cysteine-rich secretory protein family
EXW36_19375	COG3336	cytochrome c oxidase
EXW36_19400	COG0109	protoheme IX farnesyltransferase activity
EXW36_19405	COG1612	heme a metabolic process
EXW36_19410	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW36_19415	COG0772	Belongs to the SEDS family
EXW36_19420	COG4838	Belongs to the UPF0358 family
EXW36_19425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW36_19430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW36_19440	COG4896	Protein conserved in bacteria
EXW36_19455	COG1217	gtp-binding protein TYPA
EXW36_19465	COG0483	inositol monophosphate 1-phosphatase activity
EXW36_19475	COG4493	Belongs to the UPF0637 family
EXW36_19480	COG4476	Belongs to the UPF0223 family
EXW36_19485	COG1982	Orn Lys Arg decarboxylase major
EXW36_19530	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW36_19535	COG0022	dehydrogenase e1 component
EXW36_19540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW36_19555	COG0561	phosphatase activity
EXW36_19560	COG5503	Protein of unknown function (DUF1447)
EXW36_19565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW36_19570	COG0569	domain protein
EXW36_19580	COG1473	amidohydrolase
EXW36_19585	COG2171	N-acyltransferase activity
EXW36_19590	COG0583	DNA-binding transcription factor activity
EXW36_19595	COG0517	IMP dehydrogenase activity
EXW36_19605	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW36_19615	COG4703	Protein of unknown function (DUF1797)
EXW36_19630	COG2200	EAL domain
EXW36_19635	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_19640	COG1408	metallophosphoesterase
EXW36_19685	COG2814	Major facilitator Superfamily
EXW36_19695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW36_19705	COG3209	COG3209 Rhs family protein
EXW36_19715	COG2205	protein histidine kinase activity
EXW36_19725	COG0436	Aminotransferase
EXW36_19730	COG1609	Transcriptional regulator
EXW36_19735	COG3833	ABC-type maltose transport systems, permease component
EXW36_19740	COG1175	transmembrane transport
EXW36_19745	COG2182	Extracellular solute-binding protein
EXW36_19755	COG0366	Alpha amylase catalytic
EXW36_19760	COG3842	ATPase activity
EXW36_19800	COG0183	Belongs to the thiolase family
EXW36_19835	COG1695	Transcriptional regulator
EXW36_19840	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_19850	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW36_19855	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW36_19860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW36_19865	COG0436	Aminotransferase
EXW36_19870	COG1850	ribulose-bisphosphate carboxylase activity
EXW36_19875	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW36_19880	COG0235	Class ii aldolase
EXW36_19885	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW36_19900	COG2084	Dehydrogenase
EXW36_19910	COG2199	diguanylate cyclase activity
EXW36_19915	COG0778	Nitroreductase
EXW36_19940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW36_19940	COG2190	(PTS) system
EXW36_19940	COG1263	PTS System
EXW36_19945	COG3711	transcriptional antiterminator
EXW36_19955	COG2188	Transcriptional regulator
EXW36_19960	COG0363	glucosamine-6-phosphate deaminase activity
EXW36_19965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW36_19975	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW36_19980	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW36_19990	COG1547	Domain of unknown function (DUF309)
EXW36_20000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW36_20005	COG4086	secreted protein
EXW36_20010	COG0561	phosphatase activity
EXW36_20015	COG0697	spore germination
EXW36_20030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW36_20055	COG0733	neurotransmitter:sodium symporter activity
EXW36_20075	COG1686	Belongs to the peptidase S11 family
EXW36_20080	COG1725	Transcriptional regulator
EXW36_20085	COG1131	(ABC) transporter
EXW36_20110	COG1846	Transcriptional regulator
EXW36_20125	COG0598	Magnesium transport protein CorA
EXW36_20140	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW36_20150	COG4974	Belongs to the 'phage' integrase family
EXW36_20160	COG0735	belongs to the Fur family
EXW36_20165	COG1300	Membrane
EXW36_20185	COG0667	Aldo Keto reductase
EXW36_20190	COG0656	L-ascorbic acid biosynthetic process
EXW36_20195	COG0456	acetyltransferase
EXW36_20195	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW36_20205	COG4085	toxin activity
EXW36_20205	COG1525	nuclease
EXW36_20205	COG0737	Belongs to the 5'-nucleotidase family
EXW36_20210	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW36_20220	COG0596	Alpha beta hydrolase
EXW36_20225	COG2056	Na+-H+ antiporter family
EXW36_20230	COG1609	Transcriptional regulator
EXW36_20235	COG0456	acetyltransferase
EXW36_20240	COG1073	alpha beta
EXW36_20255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW36_20255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW36_20260	COG0307	riboflavin synthase, alpha
EXW36_20265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW36_20265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW36_20280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW36_20285	COG4106	trans-aconitate 2-methyltransferase activity
EXW36_20290	COG1073	alpha beta
EXW36_20290	COG2226	methyltransferase
EXW36_20295	COG0156	8-amino-7-oxononanoate synthase activity
EXW36_20305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW36_20315	COG1757	Na H antiporter
EXW36_20320	COG0737	Belongs to the 5'-nucleotidase family
EXW36_20330	COG1522	sequence-specific DNA binding
EXW36_20365	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW36_20375	COG0300	oxidoreductase activity
EXW36_20380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_20385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW36_20390	COG1760	l-serine dehydratase
EXW36_20395	COG1760	l-serine dehydratase
EXW36_20405	COG1234	tRNA 3'-trailer cleavage
EXW36_20420	COG1285	pathogenesis
EXW36_20435	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW36_20440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_20455	COG1376	ErfK ybiS ycfS ynhG family protein
EXW36_20460	COG4129	membrane
EXW36_20465	COG1126	abc transporter atp-binding protein
EXW36_20470	COG0765	amino acid transport
EXW36_20475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW36_20490	COG2816	NAD+ diphosphatase activity
EXW36_20495	COG2323	membrane
EXW36_20500	COG0772	Belongs to the SEDS family
EXW36_20505	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW36_20510	COG0022	dehydrogenase e1 component
EXW36_20515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW36_20520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW36_20525	COG3426	butyrate kinase activity
EXW36_20535	COG0280	phosphate acetyltransferase
EXW36_20540	COG3290	protein histidine kinase activity
EXW36_20540	COG3829	transcription factor binding
EXW36_20550	COG0584	glycerophosphoryl diester phosphodiesterase
EXW36_20555	COG3093	addiction module antidote protein HigA
EXW36_20595	COG0745	RESPONSE REGULATOR receiver
EXW36_20600	COG0750	zinc metalloprotease
EXW36_20605	COG0497	DNA recombination
EXW36_20610	COG1438	arginine binding
EXW36_20615	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW36_20620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW36_20625	COG0142	geranyltranstransferase activity
EXW36_20630	COG1722	exodeoxyribonuclease VII activity
EXW36_20635	COG1570	exodeoxyribonuclease VII activity
EXW36_20640	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW36_20645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW36_20650	COG1302	Protein conserved in bacteria
EXW36_20655	COG0439	Biotin carboxylase
EXW36_20660	COG0511	ligase activity, forming carbon-carbon bonds
EXW36_20705	COG3854	ATPases associated with a variety of cellular activities
EXW36_20725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW36_20730	COG0006	proline dipeptidase activity
EXW36_20735	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW36_20745	COG3872	metal-dependent enzyme
EXW36_20755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW36_20790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW36_20800	COG1609	Transcriptional regulator
EXW36_20810	COG2076	Multidrug Resistance protein
EXW36_20815	COG2076	Multidrug Resistance protein
EXW36_20850	COG1725	Transcriptional regulator
EXW36_20865	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW36_20870	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW36_20875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW36_20880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW36_20905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW36_20930	COG4970	Tfp pilus assembly protein FimT
EXW36_20940	COG1459	type II secretion system
EXW36_20945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW36_21000	COG1410	methionine synthase
EXW36_21000	COG0646	methionine synthase
EXW36_21005	COG0646	methionine synthase
EXW36_21005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW36_21010	COG0626	cystathionine gamma-synthase activity
EXW36_21015	COG0626	cystathionine gamma-synthase activity
EXW36_21030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_21040	COG1940	carbohydrate kinase activity
EXW36_21045	COG4483	Protein conserved in bacteria
EXW36_21050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW36_21055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW36_21060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW36_21065	COG0704	Plays a role in the regulation of phosphate uptake
EXW36_21075	COG0581	inorganic phosphate transmembrane transporter activity
EXW36_21080	COG0573	inorganic phosphate transmembrane transporter activity
EXW36_21085	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW36_21090	COG0768	penicillin binding
EXW36_21095	COG0477	Major facilitator Superfamily
EXW36_21100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW36_21120	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW36_21125	COG0735	belongs to the Fur family
EXW36_21130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW36_21135	COG1121	(ABC) transporter
EXW36_21140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_21150	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW36_21165	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW36_21170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW36_21175	COG2384	SAM-dependent methyltransferase
EXW36_21180	COG2010	Cytochrome c
EXW36_21185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW36_21190	COG0358	DNA primase activity
EXW36_21200	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW36_21205	COG0517	IMP dehydrogenase activity
EXW36_21210	COG1381	Involved in DNA repair and RecF pathway recombination
EXW36_21220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW36_21225	COG0295	cytidine deaminase activity
EXW36_21230	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW36_21235	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW36_21240	COG1480	7TM receptor with intracellular HD hydrolase
EXW36_21245	COG1702	phosphate starvation-inducible protein PhoH
EXW36_21260	COG1610	YqeY-like protein
EXW36_21265	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW36_21270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW36_21275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW36_21285	COG0484	heat shock protein binding
EXW36_21290	COG0443	Heat shock 70 kDa protein
EXW36_21300	COG1420	regulation of RNA biosynthetic process
EXW36_21305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW36_21310	COG1733	regulation of RNA biosynthetic process
EXW36_21315	COG0481	GTPase activity
EXW36_21325	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW36_21330	COG0268	Binds directly to 16S ribosomal RNA
EXW36_21335	COG1466	dna polymerase III delta subunit
EXW36_21345	COG0658	competence protein
EXW36_21345	COG2333	competence protein COMEC
EXW36_21350	COG2131	deaminase
EXW36_21355	COG1555	photosystem II stabilization
EXW36_21355	COG1596	polysaccharide export
EXW36_21360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW36_21365	COG2226	methyltransferase
EXW36_21370	COG0799	negative regulation of ribosome biogenesis
EXW36_21375	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW36_21380	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW36_21385	COG1534	Rna-binding protein
EXW36_21390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW36_21395	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW36_21400	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW36_21410	COG0688	phosphatidylethanolamine metabolic process
EXW36_21420	COG1595	DNA-templated transcription, initiation
EXW36_21425	COG2357	RelA SpoT domain protein
EXW36_21435	COG1785	Belongs to the alkaline phosphatase family
EXW36_21445	COG2267	carboxylic ester hydrolase activity
EXW36_21485	COG3186	Phenylalanine-4-hydroxylase
EXW36_21490	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW36_21495	COG2514	catechol 2,3-dioxygenase activity
EXW36_21500	COG2259	Doxx family
EXW36_21540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_21550	COG1454	alcohol dehydrogenase
EXW36_21550	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_21555	COG0626	cystathionine gamma-synthase activity
EXW36_21560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW36_21565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW36_21570	COG2226	methyltransferase
EXW36_21585	COG0768	penicillin binding
EXW36_21590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW36_21595	COG0572	uridine kinase
EXW36_21600	COG0826	peptidase U32
EXW36_21605	COG0826	peptidase U32
EXW36_21610	COG4122	O-methyltransferase activity
EXW36_21615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW36_21625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW36_21630	COG4472	Bacterial protein of unknown function (DUF965)
EXW36_21635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW36_21645	COG0628	permease
EXW36_21665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW36_21675	COG0482	sulfurtransferase activity
EXW36_21680	COG1104	cysteine desulfurase activity
EXW36_21685	COG1959	2 iron, 2 sulfur cluster binding
EXW36_21690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW36_21700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW36_21705	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW36_21720	COG1490	D-aminoacyl-tRNA deacylase activity
EXW36_21725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW36_21730	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW36_21735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW36_21735	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW36_21740	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW36_21745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW36_21745	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW36_21755	COG2244	polysaccharide biosynthetic process
EXW36_21760	COG2323	membrane
EXW36_21770	COG1862	Preprotein translocase
EXW36_21775	COG0343	queuine tRNA-ribosyltransferase activity
EXW36_21780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW36_21790	COG2255	four-way junction helicase activity
EXW36_21795	COG0632	four-way junction helicase activity
EXW36_21800	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW36_21825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW36_21830	COG0157	Belongs to the NadC ModD family
EXW36_21835	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW36_21840	COG1104	cysteine desulfurase activity
EXW36_21845	COG1827	regulation of RNA biosynthetic process
EXW36_21850	COG2258	MOSC domain
EXW36_21855	COG0077	Prephenate dehydratase
EXW36_21860	COG0577	efflux transmembrane transporter activity
EXW36_21865	COG0577	efflux transmembrane transporter activity
EXW36_21870	COG1136	(ABC) transporter
EXW36_21875	COG5002	protein histidine kinase activity
EXW36_21880	COG0745	RESPONSE REGULATOR receiver
EXW36_21885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW36_21890	COG3290	protein histidine kinase activity
EXW36_21900	COG2868	ribosomal protein
EXW36_21910	COG1530	ribonuclease E activity
EXW36_21915	COG1994	Peptidase M50
EXW36_21920	COG0739	heme binding
EXW36_21925	COG2894	cell division
EXW36_21930	COG0850	regulation of cytokinetic process
EXW36_21945	COG1077	Cell shape determining protein MreB Mrl
EXW36_21950	COG2003	Belongs to the UPF0758 family
EXW36_21955	COG0424	maF-like protein
EXW36_21965	COG0285	dihydrofolate synthase activity
EXW36_21980	COG1388	LysM domain
EXW36_21985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW36_21990	COG0113	porphobilinogen synthase activity
EXW36_21995	COG1587	Uroporphyrinogen-III synthase
EXW36_22000	COG0181	hydroxymethylbilane synthase activity
EXW36_22005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW36_22010	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW36_22015	COG1846	Transcriptional regulator
EXW36_22020	COG1764	response to oxidative stress
EXW36_22025	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW36_22035	COG0470	DNA polymerase III
EXW36_22035	COG1067	ATP-dependent peptidase activity
EXW36_22045	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW36_22075	COG0622	Phosphoesterase
EXW36_22085	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW36_22090	COG5401	PFAM Sporulation and spore germination
EXW36_22100	COG0477	Major facilitator Superfamily
EXW36_22105	COG2197	response regulator
EXW36_22110	COG2233	PERMEase
EXW36_22115	COG0402	S-adenosylhomocysteine deaminase activity
EXW36_22120	COG1983	PspC domain protein
EXW36_22125	COG1396	sequence-specific DNA binding
EXW36_22130	COG0697	spore germination
EXW36_22140	COG1959	2 iron, 2 sulfur cluster binding
EXW36_22145	COG1668	transmembrane transport
EXW36_22150	COG4152	abc transporter atp-binding protein
EXW36_22155	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW36_22160	COG1360	Flagellar Motor Protein
EXW36_22165	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW36_22170	COG1876	peptidase activity
EXW36_22175	COG0824	Thioesterase
EXW36_22180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW36_22185	COG1053	succinate dehydrogenase
EXW36_22190	COG2009	succinate dehydrogenase
EXW36_22195	COG1719	4-vinyl reductase, 4VR
EXW36_22200	COG0322	excinuclease ABC activity
EXW36_22205	COG3118	belongs to the thioredoxin family
EXW36_22210	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW36_22215	COG2086	electron transfer activity
EXW36_22220	COG1024	Enoyl-CoA hydratase
EXW36_22225	COG1309	transcriptional regulator
EXW36_22230	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_22250	COG2318	DinB family
EXW36_22275	COG1131	(ABC) transporter
EXW36_22280	COG2205	protein histidine kinase activity
EXW36_22285	COG0745	RESPONSE REGULATOR receiver
EXW36_22295	COG4895	conserved protein (DUF2196)
EXW36_22300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW36_22310	COG4509	Sortase family
EXW36_22315	COG1120	ATPase activity
EXW36_22330	COG5386	Cell surface protein
EXW36_22340	COG5386	Cell surface protein
EXW36_22345	COG1114	Component of the transport system for branched-chain amino acids
EXW36_22355	COG1193	negative regulation of DNA recombination
EXW36_22360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW36_22360	COG1796	DNA polymerase
EXW36_22365	COG1286	toxin biosynthetic process
EXW36_22370	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW36_22375	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW36_22400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW36_22405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW36_22415	COG1418	mRNA catabolic process
EXW36_22445	COG2814	Major facilitator Superfamily
EXW36_22450	COG1566	PFAM secretion protein HlyD family protein
EXW36_22455	COG1309	transcriptional regulator
EXW36_22460	COG1363	Peptidase, m42
EXW36_22470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW36_22485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW36_22495	COG1484	DNA-dependent DNA replication
EXW36_22500	COG3611	Membrane attachment protein
EXW36_22505	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW36_22510	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW36_22515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW36_22520	COG0237	dephospho-CoA kinase activity
EXW36_22525	COG1971	Probably functions as a manganese efflux pump
EXW36_22535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW36_22535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW36_22540	COG5002	protein histidine kinase activity
EXW36_22545	COG0745	RESPONSE REGULATOR receiver
EXW36_22560	COG0039	L-malate dehydrogenase activity
EXW36_22565	COG0538	isocitrate dehydrogenase activity
EXW36_22570	COG0372	Belongs to the citrate synthase family
EXW36_22580	COG0628	permease
EXW36_22585	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW36_22595	COG0205	6-phosphofructokinase activity
EXW36_22605	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW36_22610	COG1725	Transcriptional regulator
EXW36_22615	COG0281	malic enzyme
EXW36_22620	COG0587	DNA-directed DNA polymerase activity
EXW36_22635	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW36_22650	COG4109	DRTGG domain
EXW36_22665	COG0006	proline dipeptidase activity
EXW36_22695	COG0662	Cupin 2, conserved barrel domain protein
EXW36_22705	COG1476	TRANSCRIPTIONal
EXW36_22720	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_22725	COG0589	response to stress
EXW36_22745	COG0165	Argininosuccinate lyase
EXW36_22750	COG0137	argininosuccinate synthase activity
EXW36_22765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_22785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW36_22790	COG0827	DNA restriction-modification system
EXW36_22795	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW36_22800	COG3874	Sporulation protein YtfJ
EXW36_22815	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW36_22825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW36_22840	COG1104	cysteine desulfurase activity
EXW36_22845	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW36_22860	COG1309	transcriptional regulator
EXW36_22865	COG1956	GAF domain-containing protein
EXW36_22870	COG0626	cystathionine gamma-synthase activity
EXW36_22875	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW36_22900	COG1595	DNA-templated transcription, initiation
EXW36_22910	COG0110	maltose O-acetyltransferase activity
EXW36_22915	COG0456	acetyltransferase
EXW36_22920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW36_22925	COG0454	-acetyltransferase
EXW36_22930	COG0517	IMP dehydrogenase activity
EXW36_22935	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW36_22940	COG2267	carboxylic ester hydrolase activity
EXW36_22950	COG0745	RESPONSE REGULATOR receiver
EXW36_22955	COG5002	protein histidine kinase activity
EXW36_22960	COG0666	response to abiotic stimulus
EXW36_22970	COG1970	mechanosensitive ion channel activity
EXW36_22990	COG1609	Transcriptional regulator
EXW36_23000	COG1605	Chorismate mutase
EXW36_23000	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW36_23005	COG4851	CamS sex pheromone cAM373 precursor
EXW36_23010	COG3118	belongs to the thioredoxin family
EXW36_23020	COG2309	aminopeptidase activity
EXW36_23050	COG0697	spore germination
EXW36_23055	COG0789	Transcriptional regulator
EXW36_23060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW36_23070	COG1674	ftsk spoiiie
EXW36_23085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW36_23090	COG4848	Belongs to the UPF0354 family
EXW36_23095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_23100	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW36_23105	COG1363	Peptidase, m42
EXW36_23115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_23120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW36_23130	COG0510	thiamine kinase activity
EXW36_23135	COG1523	belongs to the glycosyl hydrolase 13 family
EXW36_23145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW36_23150	COG1349	DNA-binding transcription factor activity
EXW36_23155	COG1187	pseudouridine synthase activity
EXW36_23160	COG2244	polysaccharide biosynthetic process
EXW36_23165	COG2081	HI0933 family
EXW36_23170	COG2814	Major facilitator Superfamily
EXW36_23180	COG3832	glyoxalase III activity
EXW36_23200	COG1329	Transcriptional regulator
EXW36_23225	COG0314	molybdopterin synthase activity
EXW36_23230	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW36_23235	COG0303	'Molybdopterin
EXW36_23240	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW36_23245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW36_23250	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW36_23270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW36_23280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW36_23320	COG0495	leucyl-tRNA aminoacylation
EXW36_23325	COG2814	Major facilitator Superfamily
EXW36_23330	COG0475	glutathione-regulated potassium exporter activity
EXW36_23335	COG0490	domain, Protein
EXW36_23340	COG0582	viral genome integration into host DNA
EXW36_23350	COG1136	(ABC) transporter
EXW36_23365	COG1242	4 iron, 4 sulfur cluster binding
EXW36_23370	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW36_23375	COG1131	(ABC) transporter
EXW36_23385	COG1794	racemase activity, acting on amino acids and derivatives
EXW36_23400	COG2267	carboxylic ester hydrolase activity
EXW36_23405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW36_23410	COG0671	phosphoesterase, PA-phosphatase related
EXW36_23415	COG0438	transferase activity, transferring glycosyl groups
EXW36_23430	COG0746	molybdenum cofactor guanylyltransferase activity
EXW36_23450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW36_23455	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW36_23495	COG5002	protein histidine kinase activity
EXW36_23500	COG3852	Histidine kinase
EXW36_23505	COG0753	catalase activity
EXW36_23510	COG2267	carboxylic ester hydrolase activity
EXW36_23520	COG1368	sulfuric ester hydrolase activity
EXW36_23530	COG4895	conserved protein (DUF2196)
EXW36_23545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW36_23550	COG1116	anion transmembrane transporter activity
EXW36_23555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW36_23580	COG0494	nUDIX hydrolase
EXW36_23615	COG2076	Multidrug Resistance protein
EXW36_23620	COG2076	Multidrug Resistance protein
EXW36_23625	COG0789	Transcriptional regulator
EXW36_23630	COG1854	S-ribosylhomocysteine lyase activity
EXW36_23640	COG0288	reversible hydration of carbon dioxide
EXW36_23645	COG1271	oxidase subunit
EXW36_23650	COG1294	oxidase, subunit
EXW36_23670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_23695	COG1842	Phage shock protein A
EXW36_23720	COG3859	Proton-coupled thiamine transporter YuaJ
EXW36_23725	COG5002	protein histidine kinase activity
EXW36_23730	COG0745	RESPONSE REGULATOR receiver
EXW36_23755	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW36_23760	COG1597	lipid kinase activity
EXW36_23790	COG1136	(ABC) transporter
EXW36_23820	COG5002	protein histidine kinase activity
EXW36_23830	COG0586	Pfam SNARE associated Golgi protein
EXW36_23845	COG0577	efflux transmembrane transporter activity
EXW36_23850	COG1136	(ABC) transporter
EXW36_23855	COG2207	Transcriptional regulator
EXW36_23855	COG3708	Transcriptional regulator
EXW36_23865	COG1131	(ABC) transporter
EXW36_23875	COG5658	integral membrane protein
EXW36_23880	COG0640	Transcriptional regulator
EXW36_23885	COG0745	RESPONSE REGULATOR receiver
EXW36_23890	COG2205	protein histidine kinase activity
EXW36_23895	COG0577	efflux transmembrane transporter activity
EXW36_23900	COG0577	efflux transmembrane transporter activity
EXW36_23905	COG1136	(ABC) transporter
EXW36_23910	COG0577	efflux transmembrane transporter activity
EXW36_23925	COG2188	Transcriptional regulator
EXW36_23945	COG3964	amidohydrolase
EXW36_23965	COG4948	Mandelate Racemase Muconate Lactonizing
EXW36_23970	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_23980	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW36_23990	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW36_23995	COG1169	isochorismate synthase
EXW36_24000	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW36_24005	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW36_24010	COG1278	Cold shock
EXW36_24020	COG0789	Transcriptional regulator
EXW36_24030	COG0058	SHG alpha-glucan phosphorylase activity
EXW36_24040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW36_24045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW36_24050	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW36_24200	COG1285	pathogenesis
EXW36_24205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW36_24215	COG0166	Belongs to the GPI family
EXW36_24220	COG2155	Conserved Protein
EXW36_24225	COG1098	S1 RNA binding domain
EXW36_24230	COG0436	Aminotransferase
EXW36_24235	COG1522	sequence-specific DNA binding
EXW36_24240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW36_24245	COG2267	carboxylic ester hydrolase activity
EXW36_24255	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW36_24275	COG5018	Exonuclease
EXW36_24280	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW36_24300	COG2050	protein possibly involved in aromatic compounds catabolism
EXW36_24310	COG1268	BioY protein
EXW36_24315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW36_24320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW36_24330	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW36_24335	COG3584	3D domain protein
EXW36_24350	COG1252	NADH dehydrogenase
EXW36_24355	COG0492	ferredoxin-NADP+ reductase activity
EXW36_24360	COG3708	Transcriptional regulator
EXW36_24375	COG1683	Conserved Protein
EXW36_24395	COG0316	Belongs to the HesB IscA family
EXW36_24400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW36_24405	COG4844	belongs to the
EXW36_24410	COG1252	NADH dehydrogenase
EXW36_24420	COG0390	transport system, permease component
EXW36_24425	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW36_24455	COG4837	Protein of unknown function (DUF1462)
EXW36_24460	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW36_24470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW36_24475	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW36_24490	COG0577	efflux transmembrane transporter activity
EXW36_24490	COG1136	(ABC) transporter
EXW36_24495	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW36_24505	COG0647	UMP catabolic process
EXW36_24515	COG2445	Protein of unknown function DUF86
EXW36_24520	COG1494	fructose-1,6-bisphosphatase
EXW36_24535	COG4470	Protein conserved in bacteria
EXW36_24545	COG0789	Transcriptional regulator
EXW36_24550	COG4377	Putative membrane peptidase family (DUF2324)
EXW36_24570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW36_24575	COG0739	heme binding
EXW36_24585	COG3377	Domain of unknown function (DUF1805)
EXW36_24590	COG0737	Belongs to the 5'-nucleotidase family
EXW36_24595	COG1695	Transcriptional regulator
EXW36_24605	COG0719	Fe-S assembly protein
EXW36_24610	COG0822	iron-sulfur transferase activity
EXW36_24615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW36_24620	COG0719	Fe-S assembly protein
EXW36_24625	COG0396	ATPase activity
EXW36_24630	COG1464	Belongs to the NlpA lipoprotein family
EXW36_24635	COG1464	Belongs to the NlpA lipoprotein family
EXW36_24640	COG2011	ABC-type metal ion transport system permease component
EXW36_24645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW36_24655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_24660	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW36_24665	COG0509	glycine decarboxylation via glycine cleavage system
EXW36_24670	COG1393	Belongs to the ArsC family
EXW36_24710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_24725	COG1960	acyl-CoA dehydrogenase activity
EXW36_24730	COG0183	Belongs to the thiolase family
EXW36_24735	COG1024	Enoyl-CoA hydratase
EXW36_24735	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW36_24745	COG1686	Belongs to the peptidase S11 family
EXW36_24750	COG0506	proline dehydrogenase activity
EXW36_24760	COG0011	TIGRFAM Protein of
EXW36_24765	COG0840	transmembrane signaling receptor activity
EXW36_24780	COG2814	Major facilitator Superfamily
EXW36_24785	COG0531	amino acid
EXW36_24810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_24840	COG0586	Pfam SNARE associated Golgi protein
EXW36_24850	COG1376	ErfK ybiS ycfS ynhG family protein
EXW36_24855	COG0745	RESPONSE REGULATOR receiver
EXW36_24860	COG5002	protein histidine kinase activity
EXW36_24870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW36_24880	COG0840	transmembrane signaling receptor activity
EXW36_24885	COG0840	transmembrane signaling receptor activity
EXW36_24890	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW36_24895	COG3227	Zinc metalloprotease (Elastase)
EXW36_24900	COG1741	Belongs to the pirin family
EXW36_24915	COG0586	Pfam SNARE associated Golgi protein
EXW36_24920	COG0475	glutathione-regulated potassium exporter activity
EXW36_24925	COG0490	domain, Protein
EXW36_24930	COG1115	amino acid carrier protein
EXW36_24935	COG0783	Belongs to the Dps family
EXW36_24945	COG2318	DinB family
EXW36_24955	COG1611	Belongs to the LOG family
EXW36_24965	COG1528	Iron-storage protein
EXW36_24975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_24980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_24985	COG1115	amino acid carrier protein
EXW36_24990	COG1115	amino acid carrier protein
EXW36_24995	COG2910	NAD(P)H-binding
EXW36_25005	COG0656	L-ascorbic acid biosynthetic process
EXW36_25010	COG2814	Major facilitator Superfamily
EXW36_25015	COG1733	regulation of RNA biosynthetic process
EXW36_25025	COG1252	NADH dehydrogenase
EXW36_25045	COG0840	transmembrane signaling receptor activity
EXW36_25045	COG3290	protein histidine kinase activity
EXW36_25055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW36_25075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_25090	COG4224	UPF0291 protein
EXW36_25095	COG1335	isochorismatase
EXW36_25100	COG1522	sequence-specific DNA binding
EXW36_25110	COG1522	sequence-specific DNA binding
EXW36_25115	COG0288	reversible hydration of carbon dioxide
EXW36_25120	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW36_25125	COG2233	PERMEase
EXW36_25150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_25170	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW36_25175	COG0557	exoribonuclease II activity
EXW36_25180	COG1647	Serine aminopeptidase, S33
EXW36_25185	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW36_25190	COG1346	cytolysis
EXW36_25205	COG0148	phosphopyruvate hydratase activity
EXW36_25215	COG0149	triose-phosphate isomerase activity
EXW36_25220	COG0126	phosphoglycerate kinase activity
EXW36_25225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW36_25240	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW36_25275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW36_25290	COG2323	membrane
EXW36_25300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW36_25305	COG1481	regulation of sporulation
EXW36_25310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW36_25315	COG1660	Displays ATPase and GTPase activities
EXW36_25320	COG1051	belongs to the nudix hydrolase family
EXW36_25330	COG0492	ferredoxin-NADP+ reductase activity
EXW36_25335	COG0457	Tetratricopeptide repeat
EXW36_25340	COG0110	maltose O-acetyltransferase activity
EXW36_25345	COG0546	phosphoglycolate phosphatase activity
EXW36_25350	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW36_25355	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW36_25360	COG1950	PFAM Membrane protein of
EXW36_25365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW36_25385	COG0789	Transcriptional regulator
EXW36_25420	COG0583	DNA-binding transcription factor activity
EXW36_25425	COG0789	Transcriptional regulator
EXW36_25430	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW36_25435	COG0488	(ABC) transporter
EXW36_25445	COG1132	(ABC) transporter
EXW36_25450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW36_25455	COG0793	Belongs to the peptidase S41A family
EXW36_25455	COG3409	Peptidoglycan-binding domain 1 protein
EXW36_25460	COG2177	Part of the ABC transporter FtsEX involved in
EXW36_25465	COG2884	Cell division ATP-binding protein ftsE
EXW36_25490	COG1131	(ABC) transporter
EXW36_25525	COG1278	Cold shock
EXW36_25530	COG1040	competence protein
EXW36_25535	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW36_25540	COG0791	NLP P60 protein
EXW36_25540	COG1388	LysM domain
EXW36_25545	COG1733	regulation of RNA biosynthetic process
EXW36_25550	COG1307	EDD domain protein, DegV family
EXW36_25555	COG1739	Uncharacterized protein family UPF0029
EXW36_25560	COG1316	TRANSCRIPTIONal
EXW36_25565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW36_25570	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW36_25575	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW36_25585	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW36_25585	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW36_25605	COG1486	melibiose metabolic process
EXW36_25610	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW36_25615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW36_25635	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW36_25645	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW36_25650	COG1301	dicarboxylic acid transport
EXW36_25665	COG1511	domain protein
EXW36_25670	COG0583	DNA-binding transcription factor activity
EXW36_25675	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW36_25685	COG1271	oxidase subunit
EXW36_25690	COG1294	oxidase, subunit
EXW36_25695	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW36_25700	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW36_25705	COG1620	l-lactate permease
EXW36_25715	COG2389	metal-binding protein
EXW36_25725	COG1368	sulfuric ester hydrolase activity
EXW36_25735	COG0791	NLP P60 protein
EXW36_25735	COG1388	LysM domain
EXW36_25740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_25750	COG1215	transferase activity, transferring glycosyl groups
EXW36_25755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW36_25760	COG1388	LysM domain
EXW36_25760	COG3584	3D domain protein
EXW36_25775	COG4715	Zinc finger, swim domain protein
EXW36_25780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW36_25820	COG0577	efflux transmembrane transporter activity
EXW36_25825	COG1136	(ABC) transporter
EXW36_25855	COG5002	protein histidine kinase activity
EXW36_25855	COG3850	Histidine kinase
EXW36_25860	COG0745	RESPONSE REGULATOR receiver
EXW36_25865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW36_25875	COG1316	TRANSCRIPTIONal
EXW36_25880	COG3764	Sortase (surface protein transpeptidase)
EXW36_25915	COG0438	transferase activity, transferring glycosyl groups
EXW36_25930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW36_25935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW36_25940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW36_25945	COG4464	protein tyrosine phosphatase activity
EXW36_25950	COG0489	protein tyrosine kinase activity
EXW36_25955	COG3944	biosynthesis protein
EXW36_25965	COG1132	(ABC) transporter
EXW36_25995	COG0367	asparagine synthase
EXW36_26000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW36_26010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW36_26020	COG1216	Glycosyl transferase, family 2
EXW36_26055	COG1215	transferase activity, transferring glycosyl groups
EXW36_26075	COG0463	Glycosyl transferase, family 2
EXW36_26075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW36_26085	COG0438	transferase activity, transferring glycosyl groups
EXW36_26090	COG0438	transferase activity, transferring glycosyl groups
EXW36_26095	COG1086	Polysaccharide biosynthesis protein
EXW36_26100	COG0489	protein tyrosine kinase activity
EXW36_26105	COG3944	biosynthesis protein
EXW36_26110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW36_26115	COG0438	transferase activity, transferring glycosyl groups
EXW36_26120	COG1215	transferase activity, transferring glycosyl groups
EXW36_26120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW36_26130	COG1134	teichoic acid transport
EXW36_26135	COG1682	transport, permease protein
EXW36_26140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW36_26145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW36_26150	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EXW36_26160	COG1609	Transcriptional regulator
EXW36_26170	COG0739	heme binding
EXW36_26185	COG4555	ABC transporter
EXW36_26190	COG2385	sporulation resulting in formation of a cellular spore
EXW36_26205	COG4836	Membrane
EXW36_26210	COG1007	ATP synthesis coupled electron transport
EXW36_26215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW36_26220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW36_26225	COG0713	ATP synthesis coupled electron transport
EXW36_26230	COG0839	Belongs to the complex I subunit 6 family
EXW36_26240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW36_26245	COG0649	NAD binding
EXW36_26250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW36_26255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW36_26260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW36_26265	COG5001	Diguanylate cyclase
EXW36_26265	COG3300	MHYT domain
EXW36_26280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW36_26285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW36_26290	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW36_26295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW36_26300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW36_26305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW36_26315	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW36_26340	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW36_26350	COG0698	ribose 5-phosphate isomerase
EXW36_26360	COG2190	(PTS) system
EXW36_26365	COG2259	Doxx family
EXW36_26370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW36_26380	COG1971	Probably functions as a manganese efflux pump
EXW36_26385	COG0009	L-threonylcarbamoyladenylate synthase
EXW36_26400	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW36_26405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW36_26410	COG1435	thymidine kinase activity
EXW36_26420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW36_26425	COG1494	fructose-1,6-bisphosphatase
EXW36_26445	COG4821	SIS domain
EXW36_26450	COG0504	CTP synthase activity
EXW36_26465	COG1960	acyl-CoA dehydrogenase activity
EXW36_26470	COG1960	acyl-CoA dehydrogenase activity
EXW36_26475	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW36_26480	COG0183	Belongs to the thiolase family
EXW36_26485	COG0247	lactate metabolic process
EXW36_26485	COG2181	nitrate reductase activity
EXW36_26490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW36_26495	COG4294	response to UV
EXW36_26500	COG3300	MHYT domain
EXW36_26500	COG5001	Diguanylate cyclase
EXW36_26520	COG2197	response regulator
EXW36_26525	COG4585	Histidine kinase
EXW36_26530	COG0842	Transport permease protein
EXW36_26535	COG1131	(ABC) transporter
EXW36_26540	COG0024	Methionine aminopeptidase
EXW36_26545	COG2234	aminopeptidase activity
EXW36_26565	COG4506	Protein conserved in bacteria
EXW36_26570	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW36_26585	COG0010	Belongs to the arginase family
EXW36_26590	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW36_26595	COG2814	Major facilitator Superfamily
EXW36_26600	COG0789	Transcriptional regulator
EXW36_26605	COG0584	glycerophosphoryl diester phosphodiesterase
EXW36_26610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW36_26620	COG1994	Peptidase M50
EXW36_26630	COG1078	dGTPase activity
EXW36_26635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_26640	COG1120	ATPase activity
EXW36_26645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_26650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_26655	COG4844	belongs to the
EXW36_26670	COG0280	phosphate acetyltransferase
EXW36_26675	COG3253	May function as heme-dependent peroxidase
EXW36_26685	COG3773	Cell wall hydrolase
EXW36_26695	COG2363	Small membrane protein
EXW36_26710	COG2233	PERMEase
EXW36_26715	COG0561	phosphatase activity
EXW36_26720	COG2814	Major facilitator Superfamily
EXW36_26725	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW36_26730	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW36_26735	COG1131	(ABC) transporter
EXW36_26740	COG2755	lipolytic protein G-D-S-L family
EXW36_26745	COG1609	Transcriptional regulator
EXW36_26755	COG0460	homoserine dehydrogenase
EXW36_26760	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW36_26765	COG2873	o-acetylhomoserine
EXW36_26780	COG2197	response regulator
EXW36_26785	COG2203	Gaf domain
EXW36_26785	COG4585	Histidine kinase
EXW36_26790	COG0351	phosphomethylpyrimidine kinase
EXW36_26800	COG2879	small protein
EXW36_26805	COG1966	Carbon starvation protein
EXW36_26810	COG3279	Response regulator of the LytR AlgR family
EXW36_26815	COG0477	Major facilitator Superfamily
EXW36_26850	COG1607	acyl-coa hydrolase
EXW36_26855	COG1216	Glycosyl transferase, family 2
EXW36_26865	COG1216	Glycosyl transferase, family 2
EXW36_26875	COG4485	Bacterial membrane protein, YfhO
EXW36_26880	COG0463	Glycosyl transferase, family 2
EXW36_26895	COG1309	transcriptional regulator
EXW36_26900	COG0488	(ABC) transporter
EXW36_26905	COG1309	transcriptional regulator
EXW36_26910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW36_26915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW36_26915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW36_26920	COG0628	permease
EXW36_26930	COG1380	Effector of murein hydrolase LrgA
EXW36_26935	COG3279	Response regulator of the LytR AlgR family
EXW36_26940	COG3275	phosphorelay sensor kinase activity
EXW36_26945	COG2814	Major facilitator Superfamily
EXW36_26950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW36_26955	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW36_26960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW36_26985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW36_26990	COG1272	protein, Hemolysin III
EXW36_27015	COG1164	Oligoendopeptidase f
EXW36_27025	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW36_27035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW36_27040	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW36_27045	COG4853	Protein conserved in bacteria
EXW36_27055	COG5002	protein histidine kinase activity
EXW36_27060	COG0745	RESPONSE REGULATOR receiver
EXW36_27090	COG0305	Participates in initiation and elongation during chromosome replication
EXW36_27095	COG0359	binds to the 23S rRNA
EXW36_27100	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW36_27105	COG4241	membrane
EXW36_27115	COG0629	single-stranded DNA binding
EXW36_27120	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW36_27125	COG0012	GTP binding
EXW36_27130	COG4481	Protein conserved in bacteria
EXW36_27135	COG0668	transmembrane transport
EXW36_27145	COG1475	DNA binding
EXW36_27150	COG1192	Involved in chromosome partitioning
EXW36_27155	COG1475	DNA binding
EXW36_27160	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW36_27165	COG0445	tRNA wobble uridine modification
EXW36_27170	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW36_27175	COG1847	R3H domain protein
EXW36_27180	COG0706	membrane insertase activity
EXW36_27185	COG0594	ribonuclease P activity
EXW36_27190	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW36_27265	COG3344	reverse transcriptase
EXW36_27270	COG0741	lytic transglycosylase activity
EXW36_27270	COG0791	NLP P60 protein
EXW36_27285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW36_27300	COG0596	Alpha beta hydrolase
EXW36_27380	COG3773	Cell wall hydrolase
EXW36_27420	COG1999	signal sequence binding
EXW36_27425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW36_27430	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW36_27445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW36_27460	COG1674	ftsk spoiiie
EXW36_27475	COG2002	toxin-antitoxin pair type II binding
EXW36_27500	COG0741	lytic transglycosylase activity
EXW36_27525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_27545	COG2002	toxin-antitoxin pair type II binding
EXW36_27585	COG0457	Tetratricopeptide repeat
EXW36_28015	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW36_28150	COG3409	Peptidoglycan-binding domain 1 protein
EXW36_28150	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW36_28155	COG2373	Large extracellular alpha-helical protein
EXW36_28160	COG3227	Zinc metalloprotease (Elastase)
EXW36_28180	COG1136	(ABC) transporter
EXW36_28185	COG0577	efflux transmembrane transporter activity
EXW36_28245	COG3409	Peptidoglycan-binding domain 1 protein
EXW36_28245	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW36_28310	COG2333	competence protein COMEC
EXW36_28310	COG0658	competence protein
EXW36_28335	COG2002	toxin-antitoxin pair type II binding
EXW36_28350	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW36_28405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW36_28485	COG4974	Belongs to the 'phage' integrase family
EXW36_28630	COG0582	viral genome integration into host DNA
EXW36_28660	COG2002	toxin-antitoxin pair type II binding
EXW36_28675	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW36_28700	COG2814	Major facilitator Superfamily
EXW36_28745	COG1136	(ABC) transporter
EXW36_28750	COG0577	efflux transmembrane transporter activity
EXW36_28790	COG0519	Catalyzes the synthesis of GMP from XMP
EXW36_28820	COG0640	Transcriptional regulator
EXW36_28860	COG4641	Protein conserved in bacteria
EXW36_28865	COG2089	acid synthase
EXW36_28880	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW36_28885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW36_28890	COG1088	dTDP-glucose 4,6-dehydratase activity
EXW36_28895	COG1086	Polysaccharide biosynthesis protein
EXW36_28900	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW36_28905	COG0463	Glycosyl transferase, family 2
EXW36_28910	COG0463	Glycosyl transferase, family 2
EXW36_28940	COG3331	DNA recombination
EXW36_28965	COG0756	dUTP diphosphatase activity
EXW36_28985	COG2755	lipolytic protein G-D-S-L family
EXW36_28985	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW36_29015	COG2720	vancomycin resistance protein
EXW36_29060	COG1073	alpha beta
EXW36_29070	COG1942	4-Oxalocrotonate Tautomerase
EXW36_29075	COG0583	DNA-binding transcription factor activity
EXW36_29125	COG2801	Transposase and inactivated derivatives
EXW36_29140	COG0577	efflux transmembrane transporter activity
EXW36_29145	COG0577	efflux transmembrane transporter activity
EXW36_29155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW36_29155	COG2755	lipolytic protein G-D-S-L family
EXW36_29165	COG3331	DNA recombination
EXW36_29245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW36_29335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW36_29380	COG4974	Belongs to the 'phage' integrase family
EXW36_29390	COG0768	penicillin binding
EXW36_29435	COG2732	(Barnase) inhibitor
EXW36_29540	COG0582	viral genome integration into host DNA
EXW36_29555	COG2378	regulation of single-species biofilm formation
EXW36_29560	COG2318	DinB family
EXW36_29580	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW36_29590	COG1595	DNA-templated transcription, initiation
EXW36_29615	COG2002	toxin-antitoxin pair type II binding
EXW36_29710	COG3271	cysteine-type peptidase activity
EXW36_29710	COG2274	protein secretion by the type I secretion system
EXW36_29715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_29720	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW36_29740	COG3209	COG3209 Rhs family protein
EXW36_29780	COG0531	amino acid
EXW36_29820	COG2226	methyltransferase
EXW36_29830	COG4555	ABC transporter
EXW36_29850	COG0720	synthase
EXW36_29860	COG0302	gtp cyclohydrolase
EXW36_29915	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_29970	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW36_29980	COG2707	UPF0756 membrane protein
EXW36_29985	COG0596	Alpha beta hydrolase
EXW36_29990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW36_30010	COG2267	carboxylic ester hydrolase activity
EXW36_30015	COG1309	transcriptional regulator
EXW36_30030	COG1285	pathogenesis
EXW36_30035	COG0833	amino acid
EXW36_30055	COG0494	nUDIX hydrolase
EXW36_30140	COG3883	PFAM NLP P60 protein
EXW36_30140	COG0791	NLP P60 protein
EXW36_30270	COG1192	Involved in chromosome partitioning
EXW36_30365	COG0551	DNA topoisomerase type I activity
EXW36_30365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW36_30400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW36_30440	COG0463	Glycosyl transferase, family 2
EXW36_30465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW36_30470	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW36_30475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW36_30480	COG0438	transferase activity, transferring glycosyl groups
EXW36_30495	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW36_30500	COG0438	transferase activity, transferring glycosyl groups
EXW36_30505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW36_30595	COG3773	Cell wall hydrolase
EXW36_30675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW36_30700	COG4166	transmembrane transport
EXW36_30725	COG1192	Involved in chromosome partitioning
EXW36_30825	COG0582	viral genome integration into host DNA
EXW36_30855	COG2323	membrane
EXW36_30890	COG0662	Cupin 2, conserved barrel domain protein