locus-tag	class	description
EXW47_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW47_00010	COG0592	DNA-directed DNA polymerase activity
EXW47_00015	COG2501	S4 domain
EXW47_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW47_00025	COG0187	DNA topoisomerase II activity
EXW47_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW47_00065	COG0516	GMP reductase activity
EXW47_00065	COG0517	IMP dehydrogenase activity
EXW47_00070	COG1686	Belongs to the peptidase S11 family
EXW47_00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW47_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW47_00100	COG1428	Deoxynucleoside kinase
EXW47_00105	COG1428	Deoxynucleoside kinase
EXW47_00110	COG1335	isochorismatase
EXW47_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW47_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW47_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW47_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW47_00180	COG1982	Orn Lys Arg decarboxylase major
EXW47_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW47_00190	COG0470	DNA polymerase III
EXW47_00195	COG1774	PSP1 C-terminal conserved region
EXW47_00200	COG4467	Involved in initiation control of chromosome replication
EXW47_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW47_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW47_00220	COG2002	toxin-antitoxin pair type II binding
EXW47_00230	COG0084	hydrolase, TatD family'
EXW47_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW47_00250	COG4466	Protein conserved in bacteria
EXW47_00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW47_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW47_00270	COG0251	oxidation-reduction process
EXW47_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW47_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW47_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW47_00305	COG2002	toxin-antitoxin pair type II binding
EXW47_00310	COG2244	polysaccharide biosynthetic process
EXW47_00315	COG3956	TIGRFAM MazG family protein
EXW47_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW47_00340	COG1098	S1 RNA binding domain
EXW47_00355	COG2208	phosphoserine phosphatase activity
EXW47_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW47_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW47_00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW47_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW47_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW47_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW47_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW47_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW47_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW47_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW47_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW47_00420	COG1396	sequence-specific DNA binding
EXW47_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW47_00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW47_00515	COG3880	PFAM UvrB UvrC protein
EXW47_00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW47_00525	COG0542	response to heat
EXW47_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW47_00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW47_00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW47_00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW47_00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW47_00560	COG1045	serine acetyltransferase
EXW47_00565	COG0215	cysteine-tRNA ligase activity
EXW47_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW47_00580	COG3688	RNA-binding protein containing a PIN domain
EXW47_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW47_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW47_00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW47_00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW47_00610	COG0081	regulation of translation
EXW47_00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW47_00620	COG0222	ribosome binding
EXW47_00625	COG2813	Specifically methylates the guanine in position
EXW47_00630	COG0085	RNA polymerase activity
EXW47_00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW47_00640	COG1358	cellular component organization or biogenesis
EXW47_00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW47_00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW47_00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW47_00665	COG0051	transcription antitermination factor activity, RNA binding
EXW47_00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW47_00675	COG0088	Forms part of the polypeptide exit tunnel
EXW47_00680	COG0089	rRNA binding
EXW47_00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW47_00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW47_00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW47_00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW47_00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW47_00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW47_00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW47_00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW47_00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW47_00760	COG1841	ribosomal large subunit assembly
EXW47_00765	COG0200	Binds to the 23S rRNA
EXW47_00770	COG0201	protein transport
EXW47_00775	COG0563	adenylate kinase activity
EXW47_00780	COG0024	Methionine aminopeptidase
EXW47_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW47_00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW47_00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW47_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW47_00835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW47_00840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW47_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW47_00855	COG0489	protein tyrosine kinase activity
EXW47_00865	COG2194	sulfuric ester hydrolase activity
EXW47_00870	COG0726	polysaccharide deacetylase
EXW47_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW47_00955	COG4856	YbbR-like protein
EXW47_00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW47_00990	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_00995	COG2011	ABC-type metal ion transport system permease component
EXW47_01005	COG1464	Belongs to the NlpA lipoprotein family
EXW47_01010	COG0604	alcohol dehydrogenase
EXW47_01020	COG0277	FAD linked oxidase domain protein
EXW47_01025	COG2271	Major facilitator Superfamily
EXW47_01035	COG2814	Major facilitator Superfamily
EXW47_01050	COG0601	transmembrane transport
EXW47_01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW47_01060	COG0444	Belongs to the ABC transporter superfamily
EXW47_01065	COG4608	Belongs to the ABC transporter superfamily
EXW47_01070	COG4166	transmembrane transport
EXW47_01080	COG2207	Transcriptional regulator
EXW47_01095	COG4166	transmembrane transport
EXW47_01100	COG4166	transmembrane transport
EXW47_01105	COG0656	L-ascorbic acid biosynthetic process
EXW47_01110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW47_01125	COG4149	molybdate abc transporter
EXW47_01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW47_01135	COG1910	domain protein
EXW47_01150	COG0697	spore germination
EXW47_01165	COG0204	Acyl-transferase
EXW47_01175	COG1609	Transcriptional regulator
EXW47_01185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW47_01200	COG5298	Protein conserved in bacteria
EXW47_01225	COG0488	(ABC) transporter
EXW47_01230	COG4585	Histidine kinase
EXW47_01235	COG2197	response regulator
EXW47_01240	COG1131	(ABC) transporter
EXW47_01245	COG0842	Transport permease protein
EXW47_01245	COG1511	domain protein
EXW47_01250	COG0842	Transport permease protein
EXW47_01260	COG0747	negative chemotaxis
EXW47_01270	COG0601	transmembrane transport
EXW47_01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW47_01280	COG0444	Belongs to the ABC transporter superfamily
EXW47_01285	COG4608	Belongs to the ABC transporter superfamily
EXW47_01290	COG0561	phosphatase activity
EXW47_01320	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW47_01325	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW47_01335	COG0531	amino acid
EXW47_01340	COG2814	Major facilitator Superfamily
EXW47_01350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW47_01360	COG4294	response to UV
EXW47_01365	COG0705	Rhomboid family
EXW47_01370	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW47_01375	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW47_01385	COG0864	Transcriptional regulator
EXW47_01390	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW47_01395	COG2183	response to ionizing radiation
EXW47_01495	COG0802	atpase or kinase
EXW47_01500	COG1214	PFAM Peptidase M22, glycoprotease
EXW47_01505	COG0456	acetyltransferase
EXW47_01515	COG0488	(ABC) transporter
EXW47_01520	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW47_01530	COG1266	CAAX protease self-immunity
EXW47_01535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW47_01540	COG0459	protein refolding
EXW47_01545	COG0519	Catalyzes the synthesis of GMP from XMP
EXW47_01545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW47_01550	COG2252	PERMEase
EXW47_01560	COG5002	protein histidine kinase activity
EXW47_01585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW47_01650	COG2205	protein histidine kinase activity
EXW47_01655	COG0745	RESPONSE REGULATOR receiver
EXW47_01680	COG0697	spore germination
EXW47_01710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW47_01715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW47_01720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW47_01725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW47_01730	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW47_01735	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW47_01740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW47_01745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW47_01750	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW47_01755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW47_01760	COG0138	bifunctional purine biosynthesis protein purh
EXW47_01765	COG0151	Belongs to the GarS family
EXW47_01785	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW47_01790	COG0210	DNA helicase
EXW47_01795	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW47_01800	COG4851	CamS sex pheromone cAM373 precursor
EXW47_01810	COG1012	belongs to the aldehyde dehydrogenase family
EXW47_01815	COG1335	isochorismatase
EXW47_01825	COG2011	ABC-type metal ion transport system permease component
EXW47_01830	COG1464	Belongs to the NlpA lipoprotein family
EXW47_01845	COG0003	Pfam Anion-transporting ATPase
EXW47_01850	COG1846	Transcriptional regulator
EXW47_01855	COG4682	membrane
EXW47_01865	COG0154	amidase activity
EXW47_01870	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW47_01875	COG1597	lipid kinase activity
EXW47_01880	COG0546	phosphoglycolate phosphatase activity
EXW47_01885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW47_01895	COG1012	belongs to the aldehyde dehydrogenase family
EXW47_01900	COG2076	Multidrug Resistance protein
EXW47_01905	COG2309	aminopeptidase activity
EXW47_01920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW47_01930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW47_01935	COG5002	protein histidine kinase activity
EXW47_01940	COG4807	Protein conserved in bacteria
EXW47_01965	COG1757	Na H antiporter
EXW47_01970	COG1473	amidohydrolase
EXW47_01985	COG0450	alkyl hydroperoxide reductase
EXW47_01995	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW47_02005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW47_02010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW47_02015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW47_02025	COG0492	ferredoxin-NADP+ reductase activity
EXW47_02040	COG0166	Belongs to the GPI family
EXW47_02065	COG5002	protein histidine kinase activity
EXW47_02085	COG3541	Predicted nucleotidyltransferase
EXW47_02090	COG2814	Major facilitator Superfamily
EXW47_02095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW47_02095	COG0723	plastoquinol--plastocyanin reductase activity
EXW47_02105	COG0765	amino acid transport
EXW47_02110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW47_02120	COG0840	transmembrane signaling receptor activity
EXW47_02125	COG0277	FAD linked oxidase domain protein
EXW47_02130	COG0366	Alpha amylase catalytic
EXW47_02135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW47_02135	COG2190	(PTS) system
EXW47_02135	COG1263	PTS System
EXW47_02155	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW47_02160	COG0352	thiamine-phosphate diphosphorylase activity
EXW47_02165	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW47_02180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW47_02185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW47_02190	COG1116	anion transmembrane transporter activity
EXW47_02195	COG0488	(ABC) transporter
EXW47_02240	COG2270	Major facilitator Superfamily
EXW47_02270	COG2310	stress, protein
EXW47_02275	COG2310	stress, protein
EXW47_02280	COG2310	stress, protein
EXW47_02285	COG0861	Integral membrane protein TerC family
EXW47_02295	COG3853	Toxic anion resistance protein (TelA)
EXW47_02305	COG4840	Belongs to the UPF0435 family
EXW47_02310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW47_02320	COG1295	ribonuclease BN
EXW47_02325	COG2217	Heavy metal translocating P-type atpase
EXW47_02330	COG0697	spore germination
EXW47_02355	COG0586	Pfam SNARE associated Golgi protein
EXW47_02370	COG3871	stress protein (general stress protein 26)
EXW47_02375	COG0387	Pfam Sodium calcium exchanger
EXW47_02385	COG0535	radical SAM domain protein
EXW47_02405	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW47_02425	COG3829	transcription factor binding
EXW47_02435	COG0833	amino acid
EXW47_02440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW47_02460	COG2066	Belongs to the glutaminase family
EXW47_02470	COG1263	PTS System
EXW47_02470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW47_02475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW47_02490	COG1216	Glycosyl transferase, family 2
EXW47_02500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW47_02500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW47_02505	COG0463	Glycosyl transferase, family 2
EXW47_02520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW47_02525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW47_02540	COG1228	amidohydrolase
EXW47_02545	COG1090	epimerase
EXW47_02550	COG2137	regulation of response to DNA damage stimulus
EXW47_02575	COG1988	membrane-bound metal-dependent
EXW47_02580	COG1194	a g-specific adenine glycosylase
EXW47_02595	COG3557	Belongs to the UPF0374 family
EXW47_02600	COG1132	(ABC) transporter
EXW47_02605	COG4129	membrane
EXW47_02615	COG0069	glutamate synthase activity
EXW47_02615	COG0070	glutamate synthase
EXW47_02615	COG0067	glutamate synthase
EXW47_02620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW47_02625	COG4555	ABC transporter
EXW47_02645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW47_02650	COG0735	belongs to the Fur family
EXW47_02770	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW47_02775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW47_02795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW47_02805	COG2766	serine protein kinase
EXW47_02810	COG2718	Belongs to the UPF0229 family
EXW47_02825	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW47_02830	COG2268	Band 7 protein
EXW47_02840	COG3290	protein histidine kinase activity
EXW47_02845	COG4565	transcriptional regulatory protein
EXW47_02850	COG2851	Citrate transporter
EXW47_02875	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW47_02880	COG3842	ATPase activity
EXW47_02885	COG1175	transmembrane transport
EXW47_02890	COG0395	ABC-type sugar transport system, permease component
EXW47_02900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW47_02905	COG0745	RESPONSE REGULATOR receiver
EXW47_02910	COG5002	protein histidine kinase activity
EXW47_02920	COG4990	cell redox homeostasis
EXW47_02930	COG3290	protein histidine kinase activity
EXW47_02935	COG4565	transcriptional regulatory protein
EXW47_02940	COG3493	citrate carrier protein
EXW47_02945	COG0281	malic enzyme
EXW47_02955	COG0697	spore germination
EXW47_02960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW47_02970	COG5002	protein histidine kinase activity
EXW47_02975	COG0745	RESPONSE REGULATOR receiver
EXW47_02980	COG0456	acetyltransferase
EXW47_02985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW47_02990	COG3383	formate dehydrogenase (NAD+) activity
EXW47_02995	COG2427	Protein of unknown function (DUF1641)
EXW47_03010	COG0531	amino acid
EXW47_03020	COG0640	Transcriptional regulator
EXW47_03025	COG2217	Heavy metal translocating P-type atpase
EXW47_03030	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW47_03045	COG3227	Zinc metalloprotease (Elastase)
EXW47_03065	COG2720	vancomycin resistance protein
EXW47_03070	COG1316	TRANSCRIPTIONal
EXW47_03075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW47_03080	COG0346	lactoylglutathione lyase activity
EXW47_03085	COG1253	flavin adenine dinucleotide binding
EXW47_03090	COG1027	Aspartate ammonia-lyase
EXW47_03095	COG1620	l-lactate permease
EXW47_03100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW47_03120	COG3104	oligopeptide transport
EXW47_03125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW47_03130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW47_03135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW47_03150	COG0156	8-amino-7-oxononanoate synthase activity
EXW47_03155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW47_03165	COG4548	von Willebrand factor, type A
EXW47_03170	COG0714	Associated with various cellular activities
EXW47_03190	COG0531	amino acid
EXW47_03195	COG2188	Transcriptional regulator
EXW47_03200	COG1263	PTS System
EXW47_03200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW47_03205	COG0366	Alpha amylase catalytic
EXW47_03220	COG0697	spore germination
EXW47_03225	COG4585	Histidine kinase
EXW47_03230	COG2197	response regulator
EXW47_03235	COG1404	Belongs to the peptidase S8 family
EXW47_03250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW47_03255	COG1115	amino acid carrier protein
EXW47_03260	COG1126	abc transporter atp-binding protein
EXW47_03265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW47_03270	COG0765	amino acid transport
EXW47_03275	COG0765	amino acid transport
EXW47_03280	COG0833	amino acid
EXW47_03305	COG2378	regulation of single-species biofilm formation
EXW47_03310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW47_03315	COG5002	protein histidine kinase activity
EXW47_03330	COG0659	secondary active sulfate transmembrane transporter activity
EXW47_03345	COG0747	negative chemotaxis
EXW47_03355	COG0601	transmembrane transport
EXW47_03360	COG4608	Belongs to the ABC transporter superfamily
EXW47_03370	COG2271	Major facilitator Superfamily
EXW47_03375	COG1846	Transcriptional regulator
EXW47_03380	COG0477	Major facilitator Superfamily
EXW47_03385	COG1609	Transcriptional regulator
EXW47_03390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW47_03395	COG1869	D-ribose catabolic process
EXW47_03405	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW47_03410	COG1879	ABC-type sugar transport system periplasmic component
EXW47_03440	COG1063	alcohol dehydrogenase
EXW47_03455	COG3568	Endonuclease Exonuclease Phosphatase
EXW47_03485	COG0840	transmembrane signaling receptor activity
EXW47_03490	COG3583	domain protein
EXW47_03490	COG3584	3D domain protein
EXW47_03495	COG1476	TRANSCRIPTIONal
EXW47_03515	COG3104	oligopeptide transport
EXW47_03520	COG1114	Component of the transport system for branched-chain amino acids
EXW47_03535	COG1113	amino acid transport
EXW47_03540	COG2252	PERMEase
EXW47_03555	COG2153	protein acetylation
EXW47_03565	COG0475	glutathione-regulated potassium exporter activity
EXW47_03565	COG0569	domain protein
EXW47_03580	COG1845	cytochrome c oxidase, subunit III
EXW47_03585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW47_03595	COG0833	amino acid
EXW47_03600	COG4990	cell redox homeostasis
EXW47_03615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW47_03620	COG0697	spore germination
EXW47_03625	COG0531	amino acid
EXW47_03635	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW47_03640	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW47_03650	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW47_03655	COG0573	inorganic phosphate transmembrane transporter activity
EXW47_03660	COG0581	inorganic phosphate transmembrane transporter activity
EXW47_03670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW47_03790	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW47_03805	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW47_03805	COG3103	Sh3 type 3 domain protein
EXW47_03805	COG4991	sh3 domain protein
EXW47_03810	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW47_03815	COG1116	anion transmembrane transporter activity
EXW47_03820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW47_03825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW47_03830	COG0352	thiamine-phosphate diphosphorylase activity
EXW47_03835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW47_03840	COG2104	thiamine diphosphate biosynthetic process
EXW47_03845	COG2022	thiamine diphosphate biosynthetic process
EXW47_03850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW47_03855	COG0351	phosphomethylpyrimidine kinase
EXW47_03880	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW47_03885	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW47_03890	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW47_03895	COG2205	protein histidine kinase activity
EXW47_03900	COG2814	Major facilitator Superfamily
EXW47_03905	COG1846	Transcriptional regulator
EXW47_03925	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW47_03930	COG1129	ABC transporter
EXW47_03935	COG1879	ABC-type sugar transport system periplasmic component
EXW47_03940	COG2252	PERMEase
EXW47_03945	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_04005	COG0778	Nitroreductase
EXW47_04010	COG2719	SpoVR family
EXW47_04035	COG1937	Protein conserved in bacteria
EXW47_04040	COG0425	Belongs to the sulfur carrier protein TusA family
EXW47_04040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW47_04045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW47_04045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW47_04050	COG0425	Belongs to the sulfur carrier protein TusA family
EXW47_04055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW47_04055	COG0425	Belongs to the sulfur carrier protein TusA family
EXW47_04060	COG2210	Belongs to the sulfur carrier protein TusA family
EXW47_04065	COG0730	response to heat
EXW47_04075	COG1316	TRANSCRIPTIONal
EXW47_04080	COG0604	alcohol dehydrogenase
EXW47_04085	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW47_04090	COG0604	alcohol dehydrogenase
EXW47_04095	COG2814	Major facilitator Superfamily
EXW47_04110	COG3711	transcriptional antiterminator
EXW47_04110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW47_04115	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW47_04120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW47_04145	COG1388	LysM domain
EXW47_04145	COG3584	3D domain protein
EXW47_04150	COG0577	efflux transmembrane transporter activity
EXW47_04155	COG1136	(ABC) transporter
EXW47_04165	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW47_04180	COG1114	Component of the transport system for branched-chain amino acids
EXW47_04185	COG3546	catalase activity
EXW47_04215	COG0586	Pfam SNARE associated Golgi protein
EXW47_04250	COG0531	amino acid
EXW47_04255	COG0475	glutathione-regulated potassium exporter activity
EXW47_04265	COG1737	Transcriptional regulator
EXW47_04270	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW47_04275	COG1263	PTS System
EXW47_04275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW47_04285	COG2259	Doxx family
EXW47_04305	COG0697	spore germination
EXW47_04310	COG1522	sequence-specific DNA binding
EXW47_04320	COG0300	oxidoreductase activity
EXW47_04335	COG2076	Multidrug Resistance protein
EXW47_04340	COG1309	transcriptional regulator
EXW47_04345	COG2814	Major facilitator Superfamily
EXW47_04350	COG1733	regulation of RNA biosynthetic process
EXW47_04365	COG4533	DNA binding
EXW47_04370	COG2211	Major facilitator Superfamily
EXW47_04380	COG0693	protein deglycase activity
EXW47_04390	COG0531	amino acid
EXW47_04395	COG1012	belongs to the aldehyde dehydrogenase family
EXW47_04410	COG1132	(ABC) transporter
EXW47_04415	COG1132	(ABC) transporter
EXW47_04420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW47_04425	COG0765	amino acid transport
EXW47_04430	COG1126	abc transporter atp-binding protein
EXW47_04445	COG0189	ligase activity
EXW47_04455	COG4399	Belongs to the UPF0754 family
EXW47_04460	COG3679	Belongs to the UPF0342 family
EXW47_04475	COG0028	Belongs to the TPP enzyme family
EXW47_04480	COG3527	Alpha-acetolactate decarboxylase
EXW47_04485	COG0463	Glycosyl transferase, family 2
EXW47_04490	COG1216	Glycosyl transferase, family 2
EXW47_04495	COG2094	Belongs to the DNA glycosylase MPG family
EXW47_04500	COG0561	phosphatase activity
EXW47_04510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW47_04515	COG0318	PFAM AMP-dependent synthetase and ligase
EXW47_04525	COG0659	secondary active sulfate transmembrane transporter activity
EXW47_04540	COG0653	protein targeting
EXW47_04545	COG2244	polysaccharide biosynthetic process
EXW47_04560	COG4196	transglutaminase domain protein
EXW47_04585	COG1024	Enoyl-CoA hydratase
EXW47_04600	COG1363	Peptidase, m42
EXW47_04615	COG2318	DinB family
EXW47_04635	COG0579	oxidoreductase
EXW47_04670	COG0601	transmembrane transport
EXW47_04675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW47_04680	COG0444	Belongs to the ABC transporter superfamily
EXW47_04685	COG4608	Belongs to the ABC transporter superfamily
EXW47_04835	COG0477	Major facilitator Superfamily
EXW47_04840	COG3290	protein histidine kinase activity
EXW47_04845	COG4565	transcriptional regulatory protein
EXW47_04850	COG3181	Tripartite tricarboxylate transporter family receptor
EXW47_04855	COG0494	nUDIX hydrolase
EXW47_04905	COG0305	Participates in initiation and elongation during chromosome replication
EXW47_04935	COG0477	Major facilitator Superfamily
EXW47_05025	COG2814	Major facilitator Superfamily
EXW47_05030	COG0640	Transcriptional regulator
EXW47_05050	COG2376	Dihydroxyacetone kinase
EXW47_05065	COG2376	Dihydroxyacetone kinase
EXW47_05085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW47_05100	COG1335	isochorismatase
EXW47_05125	COG0076	glutamate decarboxylase activity
EXW47_05150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW47_05155	COG1278	Cold shock
EXW47_05165	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EXW47_05165	COG3266	domain, Protein
EXW47_05165	COG4932	domain protein
EXW47_05175	COG2409	Drug exporters of the RND superfamily
EXW47_05200	COG3237	CsbD-like
EXW47_05220	COG2172	sigma factor antagonist activity
EXW47_05225	COG1191	sigma factor activity
EXW47_05235	COG2208	phosphoserine phosphatase activity
EXW47_05240	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW47_05245	COG2205	protein histidine kinase activity
EXW47_05245	COG5002	protein histidine kinase activity
EXW47_05245	COG0784	Response regulator, receiver
EXW47_05275	COG2807	transmembrane transport
EXW47_05280	COG2186	Transcriptional regulator
EXW47_05285	COG4585	Histidine kinase
EXW47_05290	COG2197	response regulator
EXW47_05320	COG0420	3'-5' exonuclease activity
EXW47_05325	COG4717	serine-type aminopeptidase activity
EXW47_05330	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW47_05340	COG0346	lactoylglutathione lyase activity
EXW47_05345	COG0457	Tetratricopeptide repeat
EXW47_05355	COG2267	carboxylic ester hydrolase activity
EXW47_05370	COG3620	sequence-specific DNA binding
EXW47_05375	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW47_05380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW47_05385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW47_05390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW47_05395	COG1695	Transcriptional regulator
EXW47_05405	COG1595	DNA-templated transcription, initiation
EXW47_05420	COG3973	AAA domain
EXW47_05425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW47_05440	COG1846	Transcriptional regulator
EXW47_05450	COG0537	adenosine 5'-monophosphoramidase activity
EXW47_05455	COG1131	(ABC) transporter
EXW47_05460	COG4473	ABC transporter
EXW47_05470	COG0247	lactate metabolic process
EXW47_05475	COG1139	Iron-sulfur cluster binding protein
EXW47_05480	COG1556	Lactate utilization protein
EXW47_05495	COG3402	PFAM membrane-flanked domain
EXW47_05500	COG3428	Bacterial PH domain
EXW47_05540	COG3402	PFAM membrane-flanked domain
EXW47_05545	COG3428	Bacterial PH domain
EXW47_05550	COG2329	Antibiotic biosynthesis monooxygenase
EXW47_05555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW47_05560	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW47_05565	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW47_05570	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW47_05590	COG1309	transcriptional regulator
EXW47_05595	COG1511	domain protein
EXW47_05630	COG2378	regulation of single-species biofilm formation
EXW47_05635	COG1609	Transcriptional regulator
EXW47_05645	COG1234	tRNA 3'-trailer cleavage
EXW47_05650	COG0095	Lipoate-protein ligase
EXW47_05660	COG0318	PFAM AMP-dependent synthetase and ligase
EXW47_05675	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW47_05680	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW47_05685	COG4208	sulfate ABC transporter
EXW47_05700	COG1408	metallophosphoesterase
EXW47_05705	COG1078	dGTPase activity
EXW47_05720	COG1595	DNA-templated transcription, initiation
EXW47_05730	COG2207	Transcriptional regulator
EXW47_05730	COG3708	Transcriptional regulator
EXW47_05735	COG2205	protein histidine kinase activity
EXW47_05740	COG0745	RESPONSE REGULATOR receiver
EXW47_05760	COG0501	Belongs to the peptidase M48B family
EXW47_05765	COG0697	spore germination
EXW47_05795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW47_05800	COG2224	Isocitrate lyase
EXW47_05810	COG1278	Cold shock
EXW47_05830	COG4903	ComK protein
EXW47_05835	COG0398	Pfam SNARE associated Golgi protein
EXW47_05845	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW47_05850	COG1074	ATP-dependent DNA helicase activity
EXW47_05900	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW47_05925	COG0367	asparagine synthase
EXW47_05935	COG0753	catalase activity
EXW47_05940	COG0004	ammonium transporteR
EXW47_05950	COG1666	GTP binding
EXW47_05955	COG2996	Protein conserved in bacteria
EXW47_05960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW47_05970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW47_05985	COG0561	phosphatase activity
EXW47_06005	COG2267	carboxylic ester hydrolase activity
EXW47_06020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW47_06025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW47_06030	COG5504	Zn-dependent protease
EXW47_06045	COG0180	Tryptophanyl-tRNA synthetase
EXW47_06060	COG4166	transmembrane transport
EXW47_06065	COG0601	transmembrane transport
EXW47_06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW47_06075	COG0444	Belongs to the ABC transporter superfamily
EXW47_06080	COG4608	Belongs to the ABC transporter superfamily
EXW47_06085	COG0534	Mate efflux family protein
EXW47_06090	COG4166	transmembrane transport
EXW47_06110	COG0861	Integral membrane protein TerC family
EXW47_06115	COG4862	establishment of competence for transformation
EXW47_06120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW47_06130	COG1164	Oligoendopeptidase f
EXW47_06140	COG2346	COG2346, Truncated hemoglobins
EXW47_06145	COG4116	CYTH
EXW47_06155	COG2357	RelA SpoT domain protein
EXW47_06165	COG0564	pseudouridine synthase activity
EXW47_06175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW47_06180	COG0772	Belongs to the SEDS family
EXW47_06185	COG1216	Glycosyl transferase, family 2
EXW47_06205	COG0457	Tetratricopeptide repeat
EXW47_06205	COG0463	Glycosyl transferase, family 2
EXW47_06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW47_06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW47_06285	COG2153	protein acetylation
EXW47_06290	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW47_06295	COG2382	esterase
EXW47_06320	COG5492	domain, Protein
EXW47_06325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW47_06340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW47_06340	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW47_06345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW47_06350	COG0134	indole-3-glycerol-phosphate synthase activity
EXW47_06355	COG0135	phosphoribosylanthranilate isomerase activity
EXW47_06360	COG0133	tryptophan synthase activity
EXW47_06365	COG0159	tryptophan synthase activity
EXW47_06375	COG1620	l-lactate permease
EXW47_06380	COG5634	Uncharacterized conserved protein (DUF2278)
EXW47_06440	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW47_06445	COG0567	Dehydrogenase, E1 component
EXW47_06450	COG1476	TRANSCRIPTIONal
EXW47_06520	COG0322	excinuclease ABC activity
EXW47_06575	COG1686	Belongs to the peptidase S11 family
EXW47_06580	COG0681	Belongs to the peptidase S26 family
EXW47_06615	COG1012	belongs to the aldehyde dehydrogenase family
EXW47_06625	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW47_06630	COG1177	transmembrane transport
EXW47_06635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW47_06645	COG2409	Drug exporters of the RND superfamily
EXW47_06655	COG0564	pseudouridine synthase activity
EXW47_06665	COG2340	Cysteine-rich secretory protein family
EXW47_06670	COG0247	lactate metabolic process
EXW47_06675	COG0277	FAD linked oxidase domain protein
EXW47_06680	COG3835	regulator
EXW47_06690	COG0745	RESPONSE REGULATOR receiver
EXW47_06695	COG5002	protein histidine kinase activity
EXW47_06700	COG2186	Transcriptional regulator
EXW47_06705	COG0247	lactate metabolic process
EXW47_06710	COG1139	Iron-sulfur cluster binding protein
EXW47_06715	COG1556	Lactate utilization protein
EXW47_06720	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW47_06730	COG2116	formate transmembrane transporter activity
EXW47_06735	COG0861	Integral membrane protein TerC family
EXW47_06740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW47_06750	COG2030	dehydratase
EXW47_06770	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_06775	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW47_06785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW47_06800	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW47_06805	COG3842	ATPase activity
EXW47_06815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW47_06820	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW47_06830	COG1349	DNA-binding transcription factor activity
EXW47_06840	COG0235	Class ii aldolase
EXW47_06850	COG2861	carbohydrate metabolic process
EXW47_06860	COG3852	Histidine kinase
EXW47_06865	COG1846	Transcriptional regulator
EXW47_06875	COG2318	DinB family
EXW47_06880	COG5002	protein histidine kinase activity
EXW47_06885	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW47_06890	COG0720	synthase
EXW47_06900	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW47_06905	COG4873	Protein conserved in bacteria
EXW47_06915	COG0456	acetyltransferase
EXW47_06935	COG1780	Probably involved in ribonucleotide reductase function
EXW47_06950	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW47_06955	COG0531	amino acid
EXW47_06960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW47_06975	COG2204	response regulator
EXW47_06980	COG1012	belongs to the aldehyde dehydrogenase family
EXW47_06990	COG1725	Transcriptional regulator
EXW47_06995	COG1131	(ABC) transporter
EXW47_07005	COG1131	(ABC) transporter
EXW47_07010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW47_07015	COG1266	CAAX protease self-immunity
EXW47_07025	COG1522	sequence-specific DNA binding
EXW47_07035	COG1335	isochorismatase
EXW47_07045	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW47_07050	COG2070	2-Nitropropane dioxygenase
EXW47_07055	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW47_07060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW47_07065	COG1696	Membrane protein involved in D-alanine export
EXW47_07085	COG0716	FMN binding
EXW47_07110	COG0534	Mate efflux family protein
EXW47_07115	COG1968	undecaprenyl-diphosphatase activity
EXW47_07135	COG1846	Transcriptional regulator
EXW47_07145	COG1301	dicarboxylic acid transport
EXW47_07150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW47_07160	COG3874	Sporulation protein YtfJ
EXW47_07180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW47_07185	COG0028	Belongs to the TPP enzyme family
EXW47_07190	COG0440	acetolactate synthase activity
EXW47_07200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW47_07210	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW47_07220	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW47_07225	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW47_07235	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW47_07240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW47_07245	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW47_07250	COG0107	imidazoleglycerol-phosphate synthase activity
EXW47_07260	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW47_07265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW47_07280	COG1183	phosphatidylcholine synthase activity
EXW47_07285	COG1368	sulfuric ester hydrolase activity
EXW47_07295	COG0019	diaminopimelate decarboxylase activity
EXW47_07305	COG0175	sulfate reduction
EXW47_07310	COG2046	Belongs to the sulfate adenylyltransferase family
EXW47_07315	COG0529	Catalyzes the synthesis of activated sulfate
EXW47_07320	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW47_07340	COG1648	precorrin-2 dehydrogenase activity
EXW47_07350	COG0733	neurotransmitter:sodium symporter activity
EXW47_07370	COG1757	Na H antiporter
EXW47_07385	COG4758	membrane
EXW47_07390	COG4585	Histidine kinase
EXW47_07395	COG2197	response regulator
EXW47_07405	COG1114	Component of the transport system for branched-chain amino acids
EXW47_07415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW47_07455	COG0730	response to heat
EXW47_07460	COG0306	phosphate transporter
EXW47_07465	COG1392	Phosphate transport regulator
EXW47_07470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW47_07485	COG3852	Histidine kinase
EXW47_07490	COG1801	Protein of unknown function DUF72
EXW47_07500	COG0582	viral genome integration into host DNA
EXW47_07505	COG5002	protein histidine kinase activity
EXW47_07520	COG0392	lysyltransferase activity
EXW47_07520	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW47_07535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW47_07540	COG1686	Belongs to the peptidase S11 family
EXW47_07545	COG2715	membrane protein required for spore maturation
EXW47_07550	COG0700	Nucleoside recognition
EXW47_07555	COG1187	pseudouridine synthase activity
EXW47_07565	COG1333	cytochrome c biogenesis protein
EXW47_07570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW47_07575	COG0745	RESPONSE REGULATOR receiver
EXW47_07580	COG5002	protein histidine kinase activity
EXW47_07585	COG2096	Adenosyltransferase
EXW47_07590	COG4942	peptidase
EXW47_07600	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW47_07605	COG1141	Ferredoxin
EXW47_07615	COG4955	Helix-turn-helix domain
EXW47_07620	COG0514	ATP-dependent DNA helicase (RecQ)
EXW47_07625	COG1266	CAAX protease self-immunity
EXW47_07635	COG1408	metallophosphoesterase
EXW47_07650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW47_07670	COG0492	ferredoxin-NADP+ reductase activity
EXW47_07675	COG0252	asparaginase activity
EXW47_07680	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW47_07690	COG1304	FMN binding
EXW47_07725	COG1160	GTP binding
EXW47_07730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW47_07750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW47_07760	COG0302	gtp cyclohydrolase
EXW47_07765	COG0142	geranyltranstransferase activity
EXW47_07770	COG2226	methyltransferase
EXW47_07775	COG0142	geranyltranstransferase activity
EXW47_07790	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW47_07800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW47_07805	COG0457	Tetratricopeptide repeat
EXW47_07810	COG5582	Belongs to the UPF0302 family
EXW47_07825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW47_07845	COG4347	Protein of unknown function (DUF1405)
EXW47_07860	COG2738	Putative neutral zinc metallopeptidase
EXW47_07870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW47_07880	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW47_07885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW47_07890	COG1803	Methylglyoxal synthase
EXW47_07895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW47_07900	COG0438	transferase activity, transferring glycosyl groups
EXW47_07905	COG0617	tRNA 3'-terminal CCA addition
EXW47_07915	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW47_07920	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW47_07930	COG1199	ATP-dependent helicase activity
EXW47_07930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW47_07950	COG3935	DnaD domain protein
EXW47_07955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW47_07965	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW47_07965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW47_07970	COG3331	DNA recombination
EXW47_08005	COG4474	Belongs to the UPF0398 family
EXW47_08010	COG3599	regulation of cell shape
EXW47_08020	COG0116	Belongs to the methyltransferase superfamily
EXW47_08030	COG1199	ATP-dependent helicase activity
EXW47_08035	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW47_08045	COG0024	Methionine aminopeptidase
EXW47_08050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW47_08055	COG2233	PERMEase
EXW47_08060	COG2311	Membrane
EXW47_08065	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW47_08075	COG0456	acetyltransferase
EXW47_08085	COG2897	thiosulfate sulfurtransferase activity
EXW47_08125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW47_08140	COG0454	-acetyltransferase
EXW47_08160	COG0328	RNA-DNA hybrid ribonuclease activity
EXW47_08195	COG3403	YqcI/YcgG family
EXW47_08200	COG1280	lysine exporter protein (LysE YggA)
EXW47_08215	COG3162	membrane
EXW47_08220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW47_08225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW47_08235	COG0475	glutathione-regulated potassium exporter activity
EXW47_08240	COG0789	Transcriptional regulator
EXW47_08240	COG4978	Transcriptional regulator
EXW47_08250	COG2323	membrane
EXW47_08255	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW47_08285	COG2814	Major facilitator Superfamily
EXW47_08305	COG1923	regulation of RNA biosynthetic process
EXW47_08315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW47_08320	COG1360	Flagellar Motor Protein
EXW47_08325	COG2201	protein-glutamate methylesterase activity
EXW47_08330	COG2198	Histidine kinase
EXW47_08330	COG0643	Histidine kinase
EXW47_08335	COG1776	CheC inhibitor of MCP methylation
EXW47_08335	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW47_08350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW47_08370	COG1256	bacterial-type flagellum assembly
EXW47_08375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW47_08400	COG1815	bacterial-type flagellum-dependent cell motility
EXW47_08405	COG1558	bacterial-type flagellum-dependent cell motility
EXW47_08415	COG1766	The M ring may be actively involved in energy transduction
EXW47_08420	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW47_08430	COG1157	protein secretion by the type III secretion system
EXW47_08450	COG1749	Flagellar hook protein flgE
EXW47_08465	COG0784	Response regulator, receiver
EXW47_08465	COG0835	chemotaxis
EXW47_08490	COG0861	Integral membrane protein TerC family
EXW47_08500	COG3383	formate dehydrogenase (NAD+) activity
EXW47_08505	COG2427	Protein of unknown function (DUF1641)
EXW47_08510	COG5609	conserved protein (DUF2294)
EXW47_08515	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW47_08525	COG2116	formate transmembrane transporter activity
EXW47_08530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW47_08535	COG0303	'Molybdopterin
EXW47_08540	COG0314	molybdopterin synthase activity
EXW47_08545	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW47_08555	COG0489	protein tyrosine kinase activity
EXW47_08570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW47_08575	COG0741	lytic transglycosylase activity
EXW47_08585	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW47_08590	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW47_08590	COG1776	CheC inhibitor of MCP methylation
EXW47_08600	COG1338	Plays a role in the flagellum-specific transport system
EXW47_08605	COG1987	bacterial-type flagellum assembly
EXW47_08615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW47_08620	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW47_08625	COG1419	protein localization to endoplasmic reticulum
EXW47_08630	COG4786	Flagellar basal body rod
EXW47_08635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW47_08665	COG0412	Dienelactone hydrolase
EXW47_08670	COG2329	Antibiotic biosynthesis monooxygenase
EXW47_08685	COG2814	Major facilitator Superfamily
EXW47_08695	COG0583	DNA-binding transcription factor activity
EXW47_08700	COG3842	ATPase activity
EXW47_08745	COG1686	Belongs to the peptidase S11 family
EXW47_08750	COG0406	alpha-ribazole phosphatase activity
EXW47_08780	COG0367	asparagine synthase
EXW47_08810	COG1802	Transcriptional regulator
EXW47_08815	COG0697	spore germination
EXW47_08830	COG0438	transferase activity, transferring glycosyl groups
EXW47_08830	COG1216	Glycosyl transferase, family 2
EXW47_08835	COG1757	Na H antiporter
EXW47_08845	COG0277	FAD linked oxidase domain protein
EXW47_08865	COG0534	Mate efflux family protein
EXW47_08870	COG3340	Belongs to the peptidase S51 family
EXW47_08890	COG0785	Cytochrome C biogenesis protein
EXW47_08895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW47_08910	COG3048	D-serine ammonia-lyase activity
EXW47_08915	COG2733	membrane
EXW47_08955	COG1131	(ABC) transporter
EXW47_08970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW47_09005	COG0528	UMP kinase activity
EXW47_09015	COG1027	Aspartate ammonia-lyase
EXW47_09020	COG0281	malic enzyme
EXW47_09025	COG4191	Histidine kinase
EXW47_09030	COG0784	Response regulator, receiver
EXW47_09035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW47_09050	COG2502	aspartate--ammonia ligase
EXW47_09105	COG2816	NAD+ diphosphatase activity
EXW47_09120	COG2814	Major facilitator Superfamily
EXW47_09150	COG0477	Major facilitator Superfamily
EXW47_09155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW47_09165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW47_09170	COG2223	nitrite transmembrane transporter activity
EXW47_09175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW47_09185	COG2244	polysaccharide biosynthetic process
EXW47_09190	COG0733	neurotransmitter:sodium symporter activity
EXW47_09200	COG5566	PFAM Mor transcription activator
EXW47_09205	COG2323	membrane
EXW47_09220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW47_09230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW47_09235	COG0028	Belongs to the TPP enzyme family
EXW47_09250	COG0129	dihydroxy-acid dehydratase activity
EXW47_09255	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW47_09280	COG2814	Major facilitator Superfamily
EXW47_09285	COG3384	dioxygenase
EXW47_09325	COG4166	transmembrane transport
EXW47_09360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW47_09380	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW47_09385	COG1054	Belongs to the UPF0176 family
EXW47_09395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW47_09400	COG0531	amino acid
EXW47_09435	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW47_09450	COG4257	antibiotic catabolic process
EXW47_09455	COG2390	Transcriptional regulator
EXW47_09465	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW47_09470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW47_09475	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW47_09490	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW47_09505	COG0583	DNA-binding transcription factor activity
EXW47_09525	COG0006	proline dipeptidase activity
EXW47_09530	COG2132	Multicopper oxidase
EXW47_09545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW47_09555	COG0583	DNA-binding transcription factor activity
EXW47_09575	COG1114	Component of the transport system for branched-chain amino acids
EXW47_09585	COG4641	Protein conserved in bacteria
EXW47_09600	COG2372	response to copper ion
EXW47_09600	COG1276	copper resistance
EXW47_09605	COG4549	nuclear export factor GLE1
EXW47_09615	COG0697	spore germination
EXW47_09620	COG0583	DNA-binding transcription factor activity
EXW47_09625	COG1959	2 iron, 2 sulfur cluster binding
EXW47_09630	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW47_09635	COG0778	Nitroreductase
EXW47_09645	COG0628	permease
EXW47_09660	COG1231	oxidoreductase activity
EXW47_09665	COG0523	cobalamin synthesis protein
EXW47_09675	COG0318	PFAM AMP-dependent synthetase and ligase
EXW47_09680	COG2030	dehydratase
EXW47_09685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW47_09700	COG0411	ABC transporter
EXW47_09720	COG0583	DNA-binding transcription factor activity
EXW47_09730	COG1942	4-Oxalocrotonate Tautomerase
EXW47_09745	COG0346	lactoylglutathione lyase activity
EXW47_09755	COG1271	oxidase subunit
EXW47_09760	COG1294	oxidase, subunit
EXW47_09765	COG4988	ABC transporter
EXW47_09770	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW47_09800	COG1686	Belongs to the peptidase S11 family
EXW47_09815	COG1388	LysM domain
EXW47_09815	COG0791	NLP P60 protein
EXW47_09825	COG1132	(ABC) transporter
EXW47_09830	COG0745	RESPONSE REGULATOR receiver
EXW47_09835	COG5002	protein histidine kinase activity
EXW47_09840	COG0300	oxidoreductase activity
EXW47_09845	COG4122	O-methyltransferase activity
EXW47_09865	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EXW47_09875	COG0460	homoserine dehydrogenase
EXW47_09885	COG0083	homoserine kinase activity
EXW47_09900	COG1316	TRANSCRIPTIONal
EXW47_09925	COG1285	pathogenesis
EXW47_09930	COG1247	-acetyltransferase
EXW47_09950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW47_09960	COG1082	Xylose isomerase domain protein TIM barrel
EXW47_09970	COG2814	Major facilitator Superfamily
EXW47_09975	COG1279	arginine transmembrane transporter activity
EXW47_09980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW47_09990	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW47_10020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW47_10025	COG0577	efflux transmembrane transporter activity
EXW47_10030	COG2002	toxin-antitoxin pair type II binding
EXW47_10035	COG1404	Belongs to the peptidase S8 family
EXW47_10040	COG0640	Transcriptional regulator
EXW47_10045	COG0667	Aldo Keto reductase
EXW47_10050	COG2814	Major facilitator Superfamily
EXW47_10095	COG3949	Membrane
EXW47_10100	COG0783	Belongs to the Dps family
EXW47_10115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW47_10125	COG1231	oxidoreductase activity
EXW47_10130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW47_10135	COG4989	oxidoreductase activity
EXW47_10140	COG0523	cobalamin synthesis protein
EXW47_10145	COG0456	acetyltransferase
EXW47_10150	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW47_10170	COG2814	Major facilitator Superfamily
EXW47_10175	COG1136	(ABC) transporter
EXW47_10180	COG0577	efflux transmembrane transporter activity
EXW47_10185	COG0745	RESPONSE REGULATOR receiver
EXW47_10190	COG2205	protein histidine kinase activity
EXW47_10195	COG1902	pentaerythritol trinitrate reductase activity
EXW47_10200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW47_10210	COG4166	transmembrane transport
EXW47_10215	COG0346	lactoylglutathione lyase activity
EXW47_10225	COG0406	alpha-ribazole phosphatase activity
EXW47_10235	COG5337	Spore coat protein CotH
EXW47_10240	COG1051	belongs to the nudix hydrolase family
EXW47_10245	COG0586	Pfam SNARE associated Golgi protein
EXW47_10250	COG2244	polysaccharide biosynthetic process
EXW47_10260	COG0701	Predicted permease
EXW47_10265	COG3689	TIGRFAM TIGR03943 family protein
EXW47_10270	COG1607	acyl-coa hydrolase
EXW47_10280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW47_10300	COG0702	epimerase
EXW47_10305	COG2839	Protein conserved in bacteria
EXW47_10310	COG1253	flavin adenine dinucleotide binding
EXW47_10325	COG1114	Component of the transport system for branched-chain amino acids
EXW47_10330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW47_10350	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW47_10365	COG1876	peptidase activity
EXW47_10375	COG2211	Major facilitator Superfamily
EXW47_10390	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW47_10400	COG0561	phosphatase activity
EXW47_10410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW47_10430	COG1819	glycosyl
EXW47_10435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW47_10440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW47_10465	COG0456	acetyltransferase
EXW47_10500	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW47_10575	COG3874	Sporulation protein YtfJ
EXW47_10600	COG2226	methyltransferase
EXW47_10630	COG0604	alcohol dehydrogenase
EXW47_10635	COG1595	DNA-templated transcription, initiation
EXW47_10670	COG0386	Belongs to the glutathione peroxidase family
EXW47_10675	COG1305	Transglutaminase-like
EXW47_10680	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW47_10685	COG0714	Associated with various cellular activities
EXW47_10690	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW47_10695	COG1140	nitrate reductase beta subunit
EXW47_10700	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW47_10705	COG2181	nitrate reductase activity
EXW47_10710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW47_10715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW47_10720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW47_10725	COG0303	'Molybdopterin
EXW47_10730	COG0314	molybdopterin synthase activity
EXW47_10740	COG2223	nitrite transmembrane transporter activity
EXW47_10760	COG1648	precorrin-2 dehydrogenase activity
EXW47_10770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW47_10770	COG1587	Uroporphyrinogen-III synthase
EXW47_10775	COG2146	nitrite reductase [NAD(P)H] activity
EXW47_10780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW47_10785	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW47_10815	COG2359	stage V sporulation protein S
EXW47_10875	COG0582	viral genome integration into host DNA
EXW47_10880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW47_10905	COG1418	mRNA catabolic process
EXW47_10910	COG0488	(ABC) transporter
EXW47_10930	COG1413	lyase activity
EXW47_10945	COG2521	methyltransferase
EXW47_10945	COG2136	Putative SAM-dependent methyltransferase
EXW47_11010	COG0017	Asparaginyl-tRNA synthetase
EXW47_11015	COG0733	neurotransmitter:sodium symporter activity
EXW47_11040	COG2610	gluconate transmembrane transporter activity
EXW47_11050	COG1794	racemase activity, acting on amino acids and derivatives
EXW47_11060	COG0456	acetyltransferase
EXW47_11065	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW47_11075	COG1131	(ABC) transporter
EXW47_11080	COG4473	ABC transporter
EXW47_11090	COG0546	phosphoglycolate phosphatase activity
EXW47_11105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW47_11120	COG0768	penicillin binding
EXW47_11130	COG0204	Acyl-transferase
EXW47_11135	COG1272	protein, Hemolysin III
EXW47_11140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW47_11145	COG0805	protein transport
EXW47_11160	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW47_11165	COG1999	signal sequence binding
EXW47_11170	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW47_11175	COG0367	asparagine synthase
EXW47_11190	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW47_11195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW47_11200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW47_11220	COG1335	isochorismatase
EXW47_11230	COG0668	transmembrane transport
EXW47_11235	COG2203	Gaf domain
EXW47_11235	COG4585	Histidine kinase
EXW47_11240	COG2197	response regulator
EXW47_11245	COG1737	Transcriptional regulator
EXW47_11250	COG1064	alcohol dehydrogenase
EXW47_11265	COG1070	Carbohydrate kinase
EXW47_11275	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW47_11295	COG0517	IMP dehydrogenase activity
EXW47_11295	COG1125	glycine betaine transport
EXW47_11300	COG1174	glycine betaine transport
EXW47_11335	COG1253	flavin adenine dinucleotide binding
EXW47_11340	COG1012	belongs to the aldehyde dehydrogenase family
EXW47_11345	COG5506	Protein of unknown function (DUF1694)
EXW47_11360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW47_11365	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW47_11370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW47_11375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW47_11380	COG0456	acetyltransferase
EXW47_11385	COG3829	transcription factor binding
EXW47_11390	COG1509	lysine 2,3-aminomutase activity
EXW47_11400	COG4479	Belongs to the UPF0346 family
EXW47_11425	COG3064	Membrane
EXW47_11425	COG4991	sh3 domain protein
EXW47_11425	COG0515	serine threonine protein kinase
EXW47_11435	COG0671	phosphoesterase, PA-phosphatase related
EXW47_11440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW47_11445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW47_11500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW47_11530	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_11550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW47_11550	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW47_11560	COG2814	Major facilitator Superfamily
EXW47_11570	COG0372	Belongs to the citrate synthase family
EXW47_11575	COG2079	MmgE PrpD family protein
EXW47_11580	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW47_11585	COG1960	acyl-CoA dehydrogenase activity
EXW47_11590	COG2084	Dehydrogenase
EXW47_11595	COG1012	belongs to the aldehyde dehydrogenase family
EXW47_11600	COG1280	lysine exporter protein (LysE YggA)
EXW47_11605	COG1024	Enoyl-CoA hydratase
EXW47_11620	COG0420	3'-5' exonuclease activity
EXW47_11640	COG2223	nitrite transmembrane transporter activity
EXW47_11645	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_11650	COG1169	isochorismate synthase
EXW47_11655	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW47_11660	COG1535	isochorismatase
EXW47_11660	COG3433	isochorismatase activity
EXW47_11665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW47_11670	COG3251	PFAM MbtH domain protein
EXW47_11675	COG2814	Major facilitator Superfamily
EXW47_11690	COG0776	regulation of translation
EXW47_11700	COG2318	DinB family
EXW47_11705	COG1115	amino acid carrier protein
EXW47_11720	COG2329	Antibiotic biosynthesis monooxygenase
EXW47_11735	COG1187	pseudouridine synthase activity
EXW47_11740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW47_11745	COG3655	Transcriptional regulator
EXW47_11755	COG1136	(ABC) transporter
EXW47_11765	COG0596	Alpha beta hydrolase
EXW47_11780	COG0028	Belongs to the TPP enzyme family
EXW47_11805	COG1253	flavin adenine dinucleotide binding
EXW47_11835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW47_11855	COG1846	Transcriptional regulator
EXW47_11865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW47_11870	COG1309	transcriptional regulator
EXW47_11900	COG1247	-acetyltransferase
EXW47_11940	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW47_11950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW47_11980	COG0583	DNA-binding transcription factor activity
EXW47_11985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW47_12000	COG0583	DNA-binding transcription factor activity
EXW47_12005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW47_12010	COG2258	MOSC domain
EXW47_12025	COG1132	(ABC) transporter
EXW47_12030	COG1132	(ABC) transporter
EXW47_12045	COG0189	ligase activity
EXW47_12070	COG1396	sequence-specific DNA binding
EXW47_12105	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW47_12110	COG1595	DNA-templated transcription, initiation
EXW47_12210	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW47_12215	COG2971	BadF BadG BcrA BcrD
EXW47_12225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW47_12275	COG1309	transcriptional regulator
EXW47_12290	COG1136	(ABC) transporter
EXW47_12295	COG3615	Tellurite resistance protein tehB
EXW47_12295	COG0500	methyltransferase
EXW47_12305	COG0693	protein deglycase activity
EXW47_12315	COG0588	phosphoglycerate mutase activity
EXW47_12335	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW47_12340	COG0110	maltose O-acetyltransferase activity
EXW47_12355	COG1136	(ABC) transporter
EXW47_12385	COG1686	Belongs to the peptidase S11 family
EXW47_12410	COG0768	penicillin binding
EXW47_12415	COG0745	RESPONSE REGULATOR receiver
EXW47_12420	COG2205	protein histidine kinase activity
EXW47_12425	COG1136	(ABC) transporter
EXW47_12430	COG0577	efflux transmembrane transporter activity
EXW47_12440	COG1595	DNA-templated transcription, initiation
EXW47_12450	COG0768	penicillin binding
EXW47_12455	COG0768	penicillin binding
EXW47_12475	COG1252	NADH dehydrogenase
EXW47_12480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW47_12480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW47_12505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW47_12505	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW47_12530	COG1136	(ABC) transporter
EXW47_12535	COG0577	efflux transmembrane transporter activity
EXW47_12555	COG1136	(ABC) transporter
EXW47_12575	COG2723	6-phospho-beta-galactosidase activity
EXW47_12655	COG1114	Component of the transport system for branched-chain amino acids
EXW47_12665	COG2239	Acts as a magnesium transporter
EXW47_12700	COG0697	spore germination
EXW47_12725	COG3397	chitin binding
EXW47_12730	COG0823	Involved in the tonB-independent uptake of proteins
EXW47_12740	COG1408	metallophosphoesterase
EXW47_12750	COG1131	(ABC) transporter
EXW47_12760	COG1309	transcriptional regulator
EXW47_12770	COG1960	acyl-CoA dehydrogenase activity
EXW47_12775	COG0439	Biotin carboxylase
EXW47_12780	COG0511	ligase activity, forming carbon-carbon bonds
EXW47_12785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW47_12790	COG1024	Enoyl-CoA hydratase
EXW47_12795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW47_12800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW47_12815	COG3344	reverse transcriptase
EXW47_12845	COG0572	uridine kinase
EXW47_12850	COG2318	DinB family
EXW47_12880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW47_12910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW47_12935	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_12940	COG1733	regulation of RNA biosynthetic process
EXW47_12965	COG1309	transcriptional regulator
EXW47_12995	COG0697	spore germination
EXW47_13000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW47_13030	COG2323	membrane
EXW47_13045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW47_13050	COG0697	spore germination
EXW47_13070	COG0201	protein transport
EXW47_13080	COG0737	Belongs to the 5'-nucleotidase family
EXW47_13085	COG3227	Zinc metalloprotease (Elastase)
EXW47_13090	COG1523	belongs to the glycosyl hydrolase 13 family
EXW47_13105	COG0076	glutamate decarboxylase activity
EXW47_13110	COG0657	acetylesterase activity
EXW47_13120	COG1073	alpha beta
EXW47_13130	COG0577	efflux transmembrane transporter activity
EXW47_13135	COG1136	(ABC) transporter
EXW47_13150	COG5002	protein histidine kinase activity
EXW47_13155	COG0745	RESPONSE REGULATOR receiver
EXW47_13160	COG1011	Hydrolase
EXW47_13185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW47_13190	COG1183	phosphatidylcholine synthase activity
EXW47_13205	COG1132	(ABC) transporter
EXW47_13215	COG3961	Belongs to the TPP enzyme family
EXW47_13235	COG0322	excinuclease ABC activity
EXW47_13260	COG2318	DinB family
EXW47_13275	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW47_13300	COG3878	Protein conserved in bacteria
EXW47_13325	COG1051	belongs to the nudix hydrolase family
EXW47_13330	COG0592	DNA-directed DNA polymerase activity
EXW47_13335	COG2816	NAD+ diphosphatase activity
EXW47_13345	COG2223	nitrite transmembrane transporter activity
EXW47_13350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW47_13360	COG0494	nUDIX hydrolase
EXW47_13380	COG0697	spore germination
EXW47_13385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW47_13400	COG0584	glycerophosphoryl diester phosphodiesterase
EXW47_13415	COG2814	Major facilitator Superfamily
EXW47_13455	COG0768	penicillin binding
EXW47_13460	COG0671	phosphoesterase, PA-phosphatase related
EXW47_13465	COG0604	alcohol dehydrogenase
EXW47_13470	COG5002	protein histidine kinase activity
EXW47_13475	COG0745	RESPONSE REGULATOR receiver
EXW47_13485	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW47_13495	COG2205	protein histidine kinase activity
EXW47_13510	COG1122	ATPase activity
EXW47_13515	COG4720	Psort location CytoplasmicMembrane, score
EXW47_13520	COG1794	racemase activity, acting on amino acids and derivatives
EXW47_13525	COG1819	glycosyl
EXW47_13535	COG0768	penicillin binding
EXW47_13540	COG5002	protein histidine kinase activity
EXW47_13545	COG0561	phosphatase activity
EXW47_13595	COG2124	cytochrome p450
EXW47_13725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW47_13735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW47_13740	COG0460	homoserine dehydrogenase
EXW47_13760	COG0577	efflux transmembrane transporter activity
EXW47_13765	COG1136	(ABC) transporter
EXW47_13775	COG0488	(ABC) transporter
EXW47_13780	COG0667	Aldo Keto reductase
EXW47_13785	COG0583	DNA-binding transcription factor activity
EXW47_13790	COG2205	protein histidine kinase activity
EXW47_13795	COG0745	RESPONSE REGULATOR receiver
EXW47_13810	COG3773	Cell wall hydrolase
EXW47_13815	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW47_13825	COG3386	PFAM SMP-30 Gluconolaconase
EXW47_13865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW47_13880	COG2959	enzyme of heme biosynthesis
EXW47_13910	COG3483	tryptophan 2,3-dioxygenase activity
EXW47_13915	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW47_13920	COG3844	kynureninase activity
EXW47_13925	COG1309	transcriptional regulator
EXW47_13940	COG3284	Transcriptional regulator
EXW47_13955	COG1349	DNA-binding transcription factor activity
EXW47_13975	COG1959	2 iron, 2 sulfur cluster binding
EXW47_13990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW47_13995	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW47_14000	COG0022	dehydrogenase e1 component
EXW47_14005	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW47_14020	COG2207	Transcriptional regulator
EXW47_14025	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_14030	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW47_14030	COG0456	acetyltransferase
EXW47_14065	COG4176	ABC-type proline glycine betaine transport system permease component
EXW47_14070	COG0517	IMP dehydrogenase activity
EXW47_14070	COG4175	Glycine betaine
EXW47_14095	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW47_14100	COG2153	protein acetylation
EXW47_14105	COG3397	chitin binding
EXW47_14115	COG1819	glycosyl
EXW47_14130	COG2205	protein histidine kinase activity
EXW47_14135	COG2315	Protein conserved in bacteria
EXW47_14190	COG3973	AAA domain
EXW47_14200	COG2105	PFAM AIG2 family protein
EXW47_14205	COG0514	ATP-dependent DNA helicase (RecQ)
EXW47_14225	COG4637	Psort location Cytoplasmic, score
EXW47_14235	COG1227	inorganic diphosphatase activity
EXW47_14240	COG3397	chitin binding
EXW47_14245	COG2318	DinB family
EXW47_14265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW47_14270	COG1115	amino acid carrier protein
EXW47_14275	COG1012	belongs to the aldehyde dehydrogenase family
EXW47_14280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW47_14290	COG3938	Belongs to the proline racemase family
EXW47_14295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW47_14335	COG0586	Pfam SNARE associated Golgi protein
EXW47_14350	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW47_14355	COG4166	transmembrane transport
EXW47_14365	COG4948	Mandelate Racemase Muconate Lactonizing
EXW47_14385	COG0667	Aldo Keto reductase
EXW47_14425	COG2936	dipeptidyl-peptidase activity
EXW47_14435	COG0745	RESPONSE REGULATOR receiver
EXW47_14455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW47_14460	COG1164	Oligoendopeptidase f
EXW47_14475	COG1307	EDD domain protein, DegV family
EXW47_14505	COG1335	isochorismatase
EXW47_14520	COG2814	Major facilitator Superfamily
EXW47_14530	COG1664	Polymer-forming cytoskeletal
EXW47_14535	COG0789	Transcriptional regulator
EXW47_14540	COG4533	DNA binding
EXW47_14545	COG2814	Major facilitator Superfamily
EXW47_14545	COG0477	Major facilitator Superfamily
EXW47_14565	COG2261	transglycosylase associated protein
EXW47_14580	COG2226	methyltransferase
EXW47_14615	COG0436	Aminotransferase
EXW47_14620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW47_14645	COG1131	(ABC) transporter
EXW47_14650	COG2188	Transcriptional regulator
EXW47_14695	COG0628	permease
EXW47_14740	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW47_14750	COG0697	spore germination
EXW47_14755	COG2318	DinB family
EXW47_14800	COG2814	Major facilitator Superfamily
EXW47_14805	COG1368	sulfuric ester hydrolase activity
EXW47_14820	COG0488	(ABC) transporter
EXW47_14825	COG2409	Drug exporters of the RND superfamily
EXW47_14825	COG1033	growth of symbiont in host cell
EXW47_14830	COG1309	transcriptional regulator
EXW47_14850	COG0287	Prephenate dehydrogenase
EXW47_14865	COG1605	Chorismate mutase
EXW47_14865	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW47_14915	COG1388	LysM domain
EXW47_14915	COG3584	3D domain protein
EXW47_14925	COG0346	lactoylglutathione lyase activity
EXW47_14935	COG0431	NADPH-dependent FMN reductase
EXW47_14965	COG0579	oxidoreductase
EXW47_14970	COG1879	ABC-type sugar transport system periplasmic component
EXW47_14980	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW47_14985	COG1129	ABC transporter
EXW47_14990	COG2390	Transcriptional regulator
EXW47_15010	COG2226	methyltransferase
EXW47_15030	COG2329	Antibiotic biosynthesis monooxygenase
EXW47_15055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW47_15060	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW47_15065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW47_15070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW47_15075	COG3239	Fatty acid desaturase
EXW47_15095	COG3842	ATPase activity
EXW47_15120	COG1175	transmembrane transport
EXW47_15125	COG1349	DNA-binding transcription factor activity
EXW47_15135	COG3655	Transcriptional regulator
EXW47_15155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW47_15160	COG0346	lactoylglutathione lyase activity
EXW47_15195	COG0714	Associated with various cellular activities
EXW47_15215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW47_15220	COG0753	catalase activity
EXW47_15230	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW47_15255	COG0714	Associated with various cellular activities
EXW47_15265	COG0778	Nitroreductase
EXW47_15270	COG1846	Transcriptional regulator
EXW47_15295	COG4884	unkown
EXW47_15295	COG3831	ATPase activity
EXW47_15315	COG2207	Transcriptional regulator
EXW47_15320	COG0456	acetyltransferase
EXW47_15335	COG0697	spore germination
EXW47_15340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW47_15370	COG0814	amino acid
EXW47_15375	COG0697	spore germination
EXW47_15385	COG0642	Histidine kinase
EXW47_15390	COG0745	RESPONSE REGULATOR receiver
EXW47_15395	COG0596	Alpha beta hydrolase
EXW47_15405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW47_15405	COG0456	acetyltransferase
EXW47_15430	COG0730	response to heat
EXW47_15440	COG0833	amino acid
EXW47_15450	COG4335	DNA alkylation repair
EXW47_15480	COG0681	Belongs to the peptidase S26 family
EXW47_15485	COG0768	penicillin binding
EXW47_15500	COG3104	oligopeptide transport
EXW47_15505	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW47_15520	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW47_15525	COG1984	allophanate hydrolase subunit 2
EXW47_15530	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW47_15535	COG1414	Transcriptional regulator
EXW47_15555	COG1960	acyl-CoA dehydrogenase activity
EXW47_15580	COG0640	Transcriptional regulator
EXW47_15590	COG3314	Sporulation integral membrane protein YlbJ
EXW47_15610	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW47_15615	COG0577	efflux transmembrane transporter activity
EXW47_15620	COG0577	efflux transmembrane transporter activity
EXW47_15625	COG1136	(ABC) transporter
EXW47_15660	COG0574	Belongs to the PEP-utilizing enzyme family
EXW47_15660	COG3848	Pyruvate phosphate dikinase
EXW47_15670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW47_15695	COG5002	protein histidine kinase activity
EXW47_15700	COG0745	RESPONSE REGULATOR receiver
EXW47_15710	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW47_15730	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW47_15735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW47_15740	COG1121	(ABC) transporter
EXW47_15765	COG0798	PFAM Bile acid sodium symporter
EXW47_15770	COG0346	lactoylglutathione lyase activity
EXW47_15775	COG0640	Transcriptional regulator
EXW47_15790	COG1309	transcriptional regulator
EXW47_15800	COG1522	sequence-specific DNA binding
EXW47_15820	COG0346	lactoylglutathione lyase activity
EXW47_15850	COG0745	RESPONSE REGULATOR receiver
EXW47_15855	COG3850	Histidine kinase
EXW47_15855	COG5002	protein histidine kinase activity
EXW47_15890	COG1073	alpha beta
EXW47_15900	COG0814	amino acid
EXW47_15905	COG1760	l-serine dehydratase
EXW47_15910	COG1760	l-serine dehydratase
EXW47_15920	COG5002	protein histidine kinase activity
EXW47_15925	COG0745	RESPONSE REGULATOR receiver
EXW47_15935	COG5002	protein histidine kinase activity
EXW47_15960	COG4977	sequence-specific DNA binding
EXW47_16000	COG2814	Major facilitator Superfamily
EXW47_16015	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW47_16025	COG2309	aminopeptidase activity
EXW47_16035	COG1690	Belongs to the RtcB family
EXW47_16060	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW47_16080	COG1136	(ABC) transporter
EXW47_16085	COG0577	efflux transmembrane transporter activity
EXW47_16105	COG3850	Histidine kinase
EXW47_16105	COG5002	protein histidine kinase activity
EXW47_16115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW47_16130	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW47_16150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW47_16195	COG2814	Major facilitator Superfamily
EXW47_16230	COG2849	repeat protein
EXW47_16235	COG5444	nuclease activity
EXW47_16250	COG5444	nuclease activity
EXW47_16365	COG0477	Major facilitator Superfamily
EXW47_16380	COG1846	Transcriptional regulator
EXW47_16385	COG2814	Major facilitator Superfamily
EXW47_16405	COG2211	Major facilitator Superfamily
EXW47_16435	COG0640	Transcriptional regulator
EXW47_16465	COG1329	Transcriptional regulator
EXW47_16520	COG5002	protein histidine kinase activity
EXW47_16535	COG1136	(ABC) transporter
EXW47_16550	COG1131	(ABC) transporter
EXW47_16650	COG4187	Peptidase family M20/M25/M40
EXW47_16665	COG2031	fatty acid transporter
EXW47_16675	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW47_16725	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW47_16730	COG1288	antiporter activity
EXW47_16735	COG2356	endonuclease I
EXW47_16740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW47_16745	COG3620	sequence-specific DNA binding
EXW47_16765	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW47_16785	COG1785	Belongs to the alkaline phosphatase family
EXW47_16790	COG0778	Nitroreductase
EXW47_16795	COG1733	regulation of RNA biosynthetic process
EXW47_16815	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_16825	COG1131	(ABC) transporter
EXW47_16855	COG1011	Hydrolase
EXW47_16860	COG2365	Tyrosine phosphatase family
EXW47_16885	COG0346	lactoylglutathione lyase activity
EXW47_16890	COG1940	carbohydrate kinase activity
EXW47_16895	COG0738	Major facilitator superfamily
EXW47_16900	COG0110	maltose O-acetyltransferase activity
EXW47_16915	COG0628	permease
EXW47_16920	COG2261	transglycosylase associated protein
EXW47_16950	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW47_16960	COG1253	flavin adenine dinucleotide binding
EXW47_16965	COG0789	Transcriptional regulator
EXW47_16975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW47_17000	COG0697	spore germination
EXW47_17010	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW47_17015	COG3813	Protein conserved in bacteria
EXW47_17020	COG2706	6-phosphogluconolactonase activity
EXW47_17025	COG1070	Carbohydrate kinase
EXW47_17035	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW47_17040	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW47_17055	COG0814	amino acid
EXW47_17075	COG1393	Belongs to the ArsC family
EXW47_17085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW47_17100	COG0494	nUDIX hydrolase
EXW47_17115	COG0384	phenazine biosynthesis protein PhzF
EXW47_17125	COG0318	PFAM AMP-dependent synthetase and ligase
EXW47_17130	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW47_17135	COG1733	regulation of RNA biosynthetic process
EXW47_17150	COG1191	sigma factor activity
EXW47_17165	COG1876	peptidase activity
EXW47_17205	COG0741	lytic transglycosylase activity
EXW47_17230	COG5002	protein histidine kinase activity
EXW47_17280	COG0814	amino acid
EXW47_17305	COG1151	hydroxylamine reductase activity
EXW47_17335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW47_17345	COG2072	flavoprotein involved in K transport
EXW47_17390	COG1695	Transcriptional regulator
EXW47_17395	COG0604	alcohol dehydrogenase
EXW47_17400	COG1113	amino acid transport
EXW47_17410	COG2814	Major facilitator Superfamily
EXW47_17420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW47_17425	COG1012	belongs to the aldehyde dehydrogenase family
EXW47_17435	COG0534	Mate efflux family protein
EXW47_17440	COG1012	belongs to the aldehyde dehydrogenase family
EXW47_17445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW47_17460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW47_17465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW47_17485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW47_17490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW47_17495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW47_17500	COG3739	integral membrane protein
EXW47_17520	COG0583	DNA-binding transcription factor activity
EXW47_17545	COG1193	negative regulation of DNA recombination
EXW47_17565	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW47_17570	COG1164	Oligoendopeptidase f
EXW47_17575	COG2957	Belongs to the agmatine deiminase family
EXW47_17595	COG3781	membrane
EXW47_17610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW47_17645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW47_17650	COG0640	Transcriptional regulator
EXW47_17655	COG0604	alcohol dehydrogenase
EXW47_17660	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW47_17670	COG0457	Tetratricopeptide repeat
EXW47_17675	COG2808	Putative FMN-binding domain
EXW47_17685	COG0277	FAD linked oxidase domain protein
EXW47_17705	COG1285	pathogenesis
EXW47_17720	COG2514	catechol 2,3-dioxygenase activity
EXW47_17725	COG2720	vancomycin resistance protein
EXW47_17750	COG1278	Cold shock
EXW47_17760	COG0716	FMN binding
EXW47_17770	COG0494	nUDIX hydrolase
EXW47_17790	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_17800	COG0165	Argininosuccinate lyase
EXW47_17815	COG4145	pantothenate transmembrane transporter activity
EXW47_17825	COG1012	belongs to the aldehyde dehydrogenase family
EXW47_17830	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_17840	COG1657	PFAM Prenyltransferase squalene oxidase
EXW47_17845	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW47_17850	COG2962	Rard protein
EXW47_17855	COG3326	Membrane
EXW47_17860	COG0531	amino acid
EXW47_17895	COG2226	methyltransferase
EXW47_17900	COG4166	transmembrane transport
EXW47_17905	COG4166	transmembrane transport
EXW47_17910	COG4166	transmembrane transport
EXW47_17915	COG1316	TRANSCRIPTIONal
EXW47_17925	COG1595	DNA-templated transcription, initiation
EXW47_17935	COG1131	(ABC) transporter
EXW47_17955	COG0673	inositol 2-dehydrogenase activity
EXW47_17960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW47_17965	COG0187	DNA topoisomerase II activity
EXW47_17970	COG1832	CoA-binding protein
EXW47_17975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW47_17980	COG0745	RESPONSE REGULATOR receiver
EXW47_17990	COG1328	CTP reductase activity
EXW47_18000	COG4841	protein insertion into membrane
EXW47_18005	COG0824	Thioesterase
EXW47_18030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW47_18050	COG1132	(ABC) transporter
EXW47_18055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW47_18085	COG2211	Major facilitator Superfamily
EXW47_18095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW47_18110	COG0183	Belongs to the thiolase family
EXW47_18115	COG0318	PFAM AMP-dependent synthetase and ligase
EXW47_18120	COG1268	BioY protein
EXW47_18125	COG0318	PFAM AMP-dependent synthetase and ligase
EXW47_18130	COG1396	sequence-specific DNA binding
EXW47_18175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW47_18190	COG5002	protein histidine kinase activity
EXW47_18200	COG0400	carboxylic ester hydrolase activity
EXW47_18205	COG0346	lactoylglutathione lyase activity
EXW47_18210	COG0069	glutamate synthase activity
EXW47_18215	COG1902	pentaerythritol trinitrate reductase activity
EXW47_18225	COG1329	Transcriptional regulator
EXW47_18230	COG0010	Belongs to the arginase family
EXW47_18240	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW47_18245	COG2986	histidine ammonia-lyase
EXW47_18255	COG2226	methyltransferase
EXW47_18285	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW47_18290	COG0785	Cytochrome C biogenesis protein
EXW47_18305	COG1473	amidohydrolase
EXW47_18310	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW47_18315	COG1131	(ABC) transporter
EXW47_18325	COG0583	DNA-binding transcription factor activity
EXW47_18335	COG1346	cytolysis
EXW47_18350	COG0730	response to heat
EXW47_18360	COG3409	Peptidoglycan-binding domain 1 protein
EXW47_18360	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW47_18380	COG1132	(ABC) transporter
EXW47_18385	COG1132	(ABC) transporter
EXW47_18390	COG3763	UPF0154 protein
EXW47_18410	COG3639	organic phosphonate transmembrane transporter activity
EXW47_18420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW47_18425	COG0737	Belongs to the 5'-nucleotidase family
EXW47_18435	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW47_18440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW47_18455	COG1695	Transcriptional regulator
EXW47_18460	COG1132	(ABC) transporter
EXW47_18490	COG0367	asparagine synthase
EXW47_18495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW47_18505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW47_18515	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW47_18515	COG3420	alginic acid biosynthetic process
EXW47_18525	COG1442	glycosyl transferase family 8
EXW47_18530	COG1216	Glycosyl transferase, family 2
EXW47_18530	COG1442	glycosyl transferase family 8
EXW47_18545	COG0297	glycogen (starch) synthase activity
EXW47_18555	COG0438	transferase activity, transferring glycosyl groups
EXW47_18565	COG1216	Glycosyl transferase, family 2
EXW47_18570	COG0438	transferase activity, transferring glycosyl groups
EXW47_18575	COG0438	transferase activity, transferring glycosyl groups
EXW47_18580	COG1086	Polysaccharide biosynthesis protein
EXW47_18585	COG0489	protein tyrosine kinase activity
EXW47_18590	COG3944	biosynthesis protein
EXW47_18595	COG0174	glutamine synthetase
EXW47_18600	COG0789	Transcriptional regulator
EXW47_18605	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW47_18610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW47_18615	COG2860	membrane
EXW47_18620	COG0464	growth
EXW47_18640	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW47_18650	COG1388	LysM domain
EXW47_18650	COG3584	3D domain protein
EXW47_18655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW47_18655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW47_18655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW47_18660	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW47_18665	COG1349	DNA-binding transcription factor activity
EXW47_18670	COG1979	alcohol dehydrogenase
EXW47_18675	COG2322	membrane
EXW47_18685	COG1113	amino acid transport
EXW47_18700	COG1473	amidohydrolase
EXW47_18705	COG1408	metallophosphoesterase
EXW47_18710	COG2116	formate transmembrane transporter activity
EXW47_18725	COG2217	Heavy metal translocating P-type atpase
EXW47_18730	COG2608	mercury ion transmembrane transporter activity
EXW47_18735	COG1937	Protein conserved in bacteria
EXW47_18765	COG4566	intracellular signal transduction
EXW47_18775	COG2819	hydrolase of the alpha beta superfamily
EXW47_18780	COG1120	ATPase activity
EXW47_18785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW47_18790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW47_18795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW47_18800	COG0708	Exodeoxyribonuclease III
EXW47_18805	COG2169	Transcriptional regulator
EXW47_18810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW47_18815	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW47_18820	COG2706	6-phosphogluconolactonase activity
EXW47_18825	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW47_18830	COG2364	Membrane
EXW47_18840	COG0346	lactoylglutathione lyase activity
EXW47_18845	COG3300	MHYT domain
EXW47_18845	COG5001	Diguanylate cyclase
EXW47_18885	COG1346	cytolysis
EXW47_18895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW47_18900	COG0596	Alpha beta hydrolase
EXW47_18900	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW47_18905	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW47_18920	COG2188	Transcriptional regulator
EXW47_18925	COG2723	6-phospho-beta-galactosidase activity
EXW47_18930	COG0823	Involved in the tonB-independent uptake of proteins
EXW47_18935	COG3773	Cell wall hydrolase
EXW47_18945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW47_18955	COG1131	(ABC) transporter
EXW47_18990	COG1131	(ABC) transporter
EXW47_19005	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW47_19010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW47_19020	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW47_19025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW47_19030	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW47_19035	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW47_19035	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW47_19045	COG2359	stage V sporulation protein S
EXW47_19050	COG1692	metallophosphoesterase
EXW47_19055	COG1418	mRNA catabolic process
EXW47_19060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW47_19065	COG1058	Belongs to the CinA family
EXW47_19065	COG1546	Belongs to the CinA family
EXW47_19070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW47_19075	COG1426	Protein conserved in bacteria
EXW47_19090	COG0300	oxidoreductase activity
EXW47_19095	COG0612	Peptidase, M16
EXW47_19100	COG0612	Peptidase, M16
EXW47_19105	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW47_19110	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW47_19115	COG3845	ABC transporter
EXW47_19120	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW47_19125	COG2188	Transcriptional regulator
EXW47_19130	COG1674	ftsk spoiiie
EXW47_19140	COG0740	serine-type endopeptidase activity
EXW47_19145	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW47_19155	COG0527	aspartate kinase activity
EXW47_19160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW47_19165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW47_19170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW47_19175	COG1873	PFAM PRC-barrel domain
EXW47_19180	COG0612	Peptidase, M16
EXW47_19185	COG0726	polysaccharide deacetylase
EXW47_19190	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW47_19200	COG0196	riboflavin kinase activity
EXW47_19210	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW47_19215	COG1550	Protein conserved in bacteria
EXW47_19220	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW47_19225	COG1358	cellular component organization or biogenesis
EXW47_19230	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW47_19235	COG0195	Participates in both transcription termination and antitermination
EXW47_19240	COG0779	Required for maturation of 30S ribosomal subunits
EXW47_19250	COG0442	prolyl-tRNA aminoacylation
EXW47_19255	COG0750	zinc metalloprotease
EXW47_19265	COG4589	Belongs to the CDS family
EXW47_19275	COG0233	cytoplasmic translational termination
EXW47_19280	COG0528	UMP kinase activity
EXW47_19285	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW47_19295	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW47_19300	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW47_19305	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW47_19310	COG4974	Belongs to the 'phage' integrase family
EXW47_19315	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW47_19320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW47_19325	COG0758	DNA mediated transformation
EXW47_19330	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW47_19335	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW47_19340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW47_19355	COG0335	large ribosomal subunit rRNA binding
EXW47_19360	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW47_19365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW47_19370	COG1837	Belongs to the UPF0109 family
EXW47_19380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW47_19390	COG0552	protein localization to endoplasmic reticulum
EXW47_19395	COG1196	nuclear chromosome segregation
EXW47_19400	COG0571	ribonuclease III activity
EXW47_19405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW47_19410	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_19415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW47_19420	COG0416	fatty acid biosynthetic process
EXW47_19425	COG1349	DNA-binding transcription factor activity
EXW47_19425	COG2050	protein possibly involved in aromatic compounds catabolism
EXW47_19430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW47_19435	COG1461	Dihydroxyacetone kinase
EXW47_19440	COG1302	Protein conserved in bacteria
EXW47_19455	COG1564	THIamine pyrophosphokinase
EXW47_19460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW47_19470	COG0515	serine threonine protein kinase
EXW47_19470	COG2815	serine threonine protein kinase
EXW47_19475	COG0631	protein serine/threonine phosphatase activity
EXW47_19480	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW47_19485	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW47_19485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW47_19490	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW47_19495	COG0242	peptide deformylase activity
EXW47_19500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW47_19505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW47_19510	COG1758	RNA polymerase activity
EXW47_19525	COG1561	YicC-like family, N-terminal region
EXW47_19530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW47_19540	COG0006	proline dipeptidase activity
EXW47_19560	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW47_19575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EXW47_19585	COG0167	dihydroorotate dehydrogenase activity
EXW47_19590	COG0543	2 iron, 2 sulfur cluster binding
EXW47_19595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW47_19605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW47_19610	COG0540	Belongs to the ATCase OTCase family
EXW47_19620	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW47_19625	COG0564	pseudouridine synthase activity
EXW47_19630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW47_19640	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW47_19645	COG3599	regulation of cell shape
EXW47_19650	COG2302	S4 RNA-binding domain
EXW47_19655	COG0762	integral membrane protein
EXW47_19660	COG1799	cell septum assembly
EXW47_19665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW47_19675	COG1873	PFAM PRC-barrel domain
EXW47_19680	COG1191	sigma factor activity
EXW47_19685	COG1191	sigma factor activity
EXW47_19695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW47_19700	COG0849	cell division
EXW47_19705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW47_19720	COG0772	Belongs to the SEDS family
EXW47_19725	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW47_19730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW47_19735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW47_19740	COG0768	penicillin binding
EXW47_19745	COG0768	penicillin binding
EXW47_19755	COG0275	rRNA processing
EXW47_19760	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW47_19765	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW47_19770	COG0454	-acetyltransferase
EXW47_19780	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW47_19785	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW47_19790	COG1323	Belongs to the UPF0348 family
EXW47_19795	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW47_19800	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW47_19805	COG3314	Sporulation integral membrane protein YlbJ
EXW47_19815	COG0742	ribosomal rna small subunit methyltransferase
EXW47_19825	COG4471	UPF0298 protein
EXW47_19830	COG3679	Belongs to the UPF0342 family
EXW47_19835	COG0406	alpha-ribazole phosphatase activity
EXW47_19850	COG2340	Cysteine-rich secretory protein family
EXW47_19860	COG3336	cytochrome c oxidase
EXW47_19885	COG0109	protoheme IX farnesyltransferase activity
EXW47_19890	COG1612	heme a metabolic process
EXW47_19895	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW47_19905	COG0772	Belongs to the SEDS family
EXW47_19910	COG4838	Belongs to the UPF0358 family
EXW47_19915	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW47_19920	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW47_19930	COG4896	Protein conserved in bacteria
EXW47_19945	COG1217	gtp-binding protein TYPA
EXW47_19955	COG0483	inositol monophosphate 1-phosphatase activity
EXW47_19965	COG4493	Belongs to the UPF0637 family
EXW47_19970	COG4476	Belongs to the UPF0223 family
EXW47_19975	COG1982	Orn Lys Arg decarboxylase major
EXW47_20020	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW47_20025	COG0022	dehydrogenase e1 component
EXW47_20030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW47_20045	COG0561	phosphatase activity
EXW47_20055	COG5503	Protein of unknown function (DUF1447)
EXW47_20060	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW47_20065	COG0569	domain protein
EXW47_20075	COG1473	amidohydrolase
EXW47_20080	COG2171	N-acyltransferase activity
EXW47_20085	COG0583	DNA-binding transcription factor activity
EXW47_20090	COG0517	IMP dehydrogenase activity
EXW47_20100	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW47_20110	COG4703	Protein of unknown function (DUF1797)
EXW47_20125	COG2200	EAL domain
EXW47_20130	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_20135	COG1408	metallophosphoesterase
EXW47_20180	COG2814	Major facilitator Superfamily
EXW47_20190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW47_20200	COG3209	COG3209 Rhs family protein
EXW47_20210	COG2205	protein histidine kinase activity
EXW47_20220	COG0436	Aminotransferase
EXW47_20225	COG1609	Transcriptional regulator
EXW47_20230	COG3833	ABC-type maltose transport systems, permease component
EXW47_20235	COG1175	transmembrane transport
EXW47_20240	COG2182	Extracellular solute-binding protein
EXW47_20250	COG0366	Alpha amylase catalytic
EXW47_20255	COG3842	ATPase activity
EXW47_20300	COG0183	Belongs to the thiolase family
EXW47_20335	COG1695	Transcriptional regulator
EXW47_20340	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_20350	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW47_20355	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW47_20360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW47_20365	COG0436	Aminotransferase
EXW47_20370	COG1850	ribulose-bisphosphate carboxylase activity
EXW47_20375	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW47_20380	COG0235	Class ii aldolase
EXW47_20385	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW47_20400	COG2084	Dehydrogenase
EXW47_20410	COG2199	diguanylate cyclase activity
EXW47_20415	COG0778	Nitroreductase
EXW47_20440	COG1263	PTS System
EXW47_20440	COG2190	(PTS) system
EXW47_20440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW47_20445	COG3711	transcriptional antiterminator
EXW47_20455	COG2188	Transcriptional regulator
EXW47_20460	COG0363	glucosamine-6-phosphate deaminase activity
EXW47_20465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW47_20475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW47_20485	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW47_20495	COG1547	Domain of unknown function (DUF309)
EXW47_20505	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW47_20510	COG4086	secreted protein
EXW47_20515	COG0561	phosphatase activity
EXW47_20520	COG0697	spore germination
EXW47_20535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW47_20560	COG0733	neurotransmitter:sodium symporter activity
EXW47_20580	COG1686	Belongs to the peptidase S11 family
EXW47_20585	COG1725	Transcriptional regulator
EXW47_20590	COG1131	(ABC) transporter
EXW47_20610	COG1846	Transcriptional regulator
EXW47_20625	COG0598	Magnesium transport protein CorA
EXW47_20640	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW47_20650	COG4974	Belongs to the 'phage' integrase family
EXW47_20660	COG0735	belongs to the Fur family
EXW47_20665	COG1300	Membrane
EXW47_20685	COG0667	Aldo Keto reductase
EXW47_20690	COG0656	L-ascorbic acid biosynthetic process
EXW47_20695	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW47_20695	COG0456	acetyltransferase
EXW47_20705	COG4085	toxin activity
EXW47_20705	COG0737	Belongs to the 5'-nucleotidase family
EXW47_20705	COG1525	nuclease
EXW47_20710	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW47_20720	COG0596	Alpha beta hydrolase
EXW47_20725	COG2056	Na+-H+ antiporter family
EXW47_20730	COG1609	Transcriptional regulator
EXW47_20735	COG0456	acetyltransferase
EXW47_20740	COG1073	alpha beta
EXW47_20755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW47_20755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW47_20760	COG0307	riboflavin synthase, alpha
EXW47_20765	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW47_20765	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW47_20780	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW47_20785	COG4106	trans-aconitate 2-methyltransferase activity
EXW47_20790	COG1073	alpha beta
EXW47_20790	COG2226	methyltransferase
EXW47_20795	COG0156	8-amino-7-oxononanoate synthase activity
EXW47_20805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW47_20815	COG1757	Na H antiporter
EXW47_20820	COG0737	Belongs to the 5'-nucleotidase family
EXW47_20830	COG1522	sequence-specific DNA binding
EXW47_20865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW47_20875	COG0300	oxidoreductase activity
EXW47_20880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW47_20885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW47_20890	COG1760	l-serine dehydratase
EXW47_20895	COG1760	l-serine dehydratase
EXW47_20905	COG1234	tRNA 3'-trailer cleavage
EXW47_20930	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW47_20935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW47_20945	COG1376	ErfK ybiS ycfS ynhG family protein
EXW47_20950	COG4129	membrane
EXW47_20955	COG1126	abc transporter atp-binding protein
EXW47_20960	COG0765	amino acid transport
EXW47_20965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW47_20980	COG2816	NAD+ diphosphatase activity
EXW47_20985	COG2323	membrane
EXW47_20990	COG0772	Belongs to the SEDS family
EXW47_21000	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW47_21005	COG0022	dehydrogenase e1 component
EXW47_21010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW47_21015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW47_21020	COG3426	butyrate kinase activity
EXW47_21030	COG0280	phosphate acetyltransferase
EXW47_21040	COG3829	transcription factor binding
EXW47_21040	COG3290	protein histidine kinase activity
EXW47_21050	COG0584	glycerophosphoryl diester phosphodiesterase
EXW47_21055	COG3093	addiction module antidote protein HigA
EXW47_21085	COG0745	RESPONSE REGULATOR receiver
EXW47_21095	COG0750	zinc metalloprotease
EXW47_21100	COG0497	DNA recombination
EXW47_21105	COG1438	arginine binding
EXW47_21110	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW47_21115	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW47_21120	COG0142	geranyltranstransferase activity
EXW47_21125	COG1722	exodeoxyribonuclease VII activity
EXW47_21130	COG1570	exodeoxyribonuclease VII activity
EXW47_21135	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW47_21140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW47_21145	COG1302	Protein conserved in bacteria
EXW47_21150	COG0439	Biotin carboxylase
EXW47_21155	COG0511	ligase activity, forming carbon-carbon bonds
EXW47_21200	COG3854	ATPases associated with a variety of cellular activities
EXW47_21220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW47_21225	COG0006	proline dipeptidase activity
EXW47_21230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW47_21240	COG3872	metal-dependent enzyme
EXW47_21250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW47_21285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW47_21295	COG1609	Transcriptional regulator
EXW47_21305	COG2076	Multidrug Resistance protein
EXW47_21310	COG2076	Multidrug Resistance protein
EXW47_21350	COG1725	Transcriptional regulator
EXW47_21365	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW47_21370	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW47_21375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW47_21380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW47_21410	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW47_21435	COG4970	Tfp pilus assembly protein FimT
EXW47_21445	COG1459	type II secretion system
EXW47_21450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW47_21505	COG0646	methionine synthase
EXW47_21505	COG1410	methionine synthase
EXW47_21510	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW47_21510	COG0646	methionine synthase
EXW47_21515	COG0626	cystathionine gamma-synthase activity
EXW47_21520	COG0626	cystathionine gamma-synthase activity
EXW47_21540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW47_21550	COG1940	carbohydrate kinase activity
EXW47_21555	COG4483	Protein conserved in bacteria
EXW47_21560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW47_21565	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW47_21570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW47_21575	COG0704	Plays a role in the regulation of phosphate uptake
EXW47_21585	COG0581	inorganic phosphate transmembrane transporter activity
EXW47_21590	COG0573	inorganic phosphate transmembrane transporter activity
EXW47_21595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW47_21600	COG0768	penicillin binding
EXW47_21605	COG0477	Major facilitator Superfamily
EXW47_21610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW47_21630	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW47_21635	COG0735	belongs to the Fur family
EXW47_21640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW47_21645	COG1121	(ABC) transporter
EXW47_21650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW47_21660	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW47_21675	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW47_21680	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW47_21685	COG2384	SAM-dependent methyltransferase
EXW47_21690	COG2010	Cytochrome c
EXW47_21695	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW47_21700	COG0358	DNA primase activity
EXW47_21710	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW47_21715	COG0517	IMP dehydrogenase activity
EXW47_21720	COG1381	Involved in DNA repair and RecF pathway recombination
EXW47_21730	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW47_21735	COG0295	cytidine deaminase activity
EXW47_21740	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW47_21745	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW47_21750	COG1480	7TM receptor with intracellular HD hydrolase
EXW47_21755	COG1702	phosphate starvation-inducible protein PhoH
EXW47_21770	COG1610	YqeY-like protein
EXW47_21775	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW47_21780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW47_21785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW47_21795	COG0484	heat shock protein binding
EXW47_21800	COG0443	Heat shock 70 kDa protein
EXW47_21810	COG1420	regulation of RNA biosynthetic process
EXW47_21815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW47_21820	COG1733	regulation of RNA biosynthetic process
EXW47_21825	COG0481	GTPase activity
EXW47_21835	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW47_21840	COG0268	Binds directly to 16S ribosomal RNA
EXW47_21845	COG1466	dna polymerase III delta subunit
EXW47_21855	COG0658	competence protein
EXW47_21855	COG2333	competence protein COMEC
EXW47_21860	COG2131	deaminase
EXW47_21865	COG1596	polysaccharide export
EXW47_21865	COG1555	photosystem II stabilization
EXW47_21870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW47_21875	COG2226	methyltransferase
EXW47_21880	COG0799	negative regulation of ribosome biogenesis
EXW47_21885	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW47_21890	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW47_21895	COG1534	Rna-binding protein
EXW47_21900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW47_21905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW47_21910	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW47_21920	COG0688	phosphatidylethanolamine metabolic process
EXW47_21930	COG1595	DNA-templated transcription, initiation
EXW47_21935	COG2357	RelA SpoT domain protein
EXW47_21945	COG1785	Belongs to the alkaline phosphatase family
EXW47_21955	COG2267	carboxylic ester hydrolase activity
EXW47_21990	COG1404	Belongs to the peptidase S8 family
EXW47_21995	COG3186	Phenylalanine-4-hydroxylase
EXW47_22000	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW47_22005	COG2514	catechol 2,3-dioxygenase activity
EXW47_22010	COG2259	Doxx family
EXW47_22050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW47_22060	COG1012	belongs to the aldehyde dehydrogenase family
EXW47_22060	COG1454	alcohol dehydrogenase
EXW47_22065	COG0626	cystathionine gamma-synthase activity
EXW47_22070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW47_22075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW47_22080	COG2226	methyltransferase
EXW47_22095	COG0768	penicillin binding
EXW47_22100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW47_22105	COG0572	uridine kinase
EXW47_22110	COG0826	peptidase U32
EXW47_22115	COG0826	peptidase U32
EXW47_22120	COG4122	O-methyltransferase activity
EXW47_22125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW47_22135	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW47_22140	COG4472	Bacterial protein of unknown function (DUF965)
EXW47_22145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW47_22155	COG0628	permease
EXW47_22175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW47_22185	COG0482	sulfurtransferase activity
EXW47_22190	COG1104	cysteine desulfurase activity
EXW47_22195	COG1959	2 iron, 2 sulfur cluster binding
EXW47_22200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW47_22210	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW47_22215	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW47_22225	COG1490	D-aminoacyl-tRNA deacylase activity
EXW47_22230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW47_22235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW47_22240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW47_22240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW47_22245	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW47_22250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW47_22250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW47_22260	COG2244	polysaccharide biosynthetic process
EXW47_22265	COG2323	membrane
EXW47_22275	COG1862	Preprotein translocase
EXW47_22280	COG0343	queuine tRNA-ribosyltransferase activity
EXW47_22285	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW47_22295	COG2255	four-way junction helicase activity
EXW47_22300	COG0632	four-way junction helicase activity
EXW47_22305	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW47_22330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW47_22335	COG0157	Belongs to the NadC ModD family
EXW47_22340	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW47_22345	COG1104	cysteine desulfurase activity
EXW47_22350	COG1827	regulation of RNA biosynthetic process
EXW47_22355	COG2258	MOSC domain
EXW47_22360	COG0077	Prephenate dehydratase
EXW47_22365	COG0577	efflux transmembrane transporter activity
EXW47_22370	COG0577	efflux transmembrane transporter activity
EXW47_22375	COG1136	(ABC) transporter
EXW47_22380	COG5002	protein histidine kinase activity
EXW47_22385	COG0745	RESPONSE REGULATOR receiver
EXW47_22390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW47_22395	COG3290	protein histidine kinase activity
EXW47_22405	COG2868	ribosomal protein
EXW47_22415	COG1530	ribonuclease E activity
EXW47_22420	COG1994	Peptidase M50
EXW47_22425	COG0739	heme binding
EXW47_22430	COG2894	cell division
EXW47_22435	COG0850	regulation of cytokinetic process
EXW47_22450	COG1077	Cell shape determining protein MreB Mrl
EXW47_22455	COG2003	Belongs to the UPF0758 family
EXW47_22460	COG0424	maF-like protein
EXW47_22475	COG0285	dihydrofolate synthase activity
EXW47_22490	COG1388	LysM domain
EXW47_22495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW47_22500	COG0113	porphobilinogen synthase activity
EXW47_22505	COG1587	Uroporphyrinogen-III synthase
EXW47_22510	COG0181	hydroxymethylbilane synthase activity
EXW47_22515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW47_22520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW47_22525	COG1846	Transcriptional regulator
EXW47_22530	COG1764	response to oxidative stress
EXW47_22535	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW47_22545	COG0470	DNA polymerase III
EXW47_22545	COG1067	ATP-dependent peptidase activity
EXW47_22555	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW47_22630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW47_22680	COG0622	Phosphoesterase
EXW47_22690	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW47_22695	COG5401	PFAM Sporulation and spore germination
EXW47_22705	COG0477	Major facilitator Superfamily
EXW47_22710	COG2197	response regulator
EXW47_22715	COG2233	PERMEase
EXW47_22720	COG0402	S-adenosylhomocysteine deaminase activity
EXW47_22725	COG1983	PspC domain protein
EXW47_22730	COG1396	sequence-specific DNA binding
EXW47_22735	COG0697	spore germination
EXW47_22745	COG1959	2 iron, 2 sulfur cluster binding
EXW47_22750	COG1668	transmembrane transport
EXW47_22755	COG4152	abc transporter atp-binding protein
EXW47_22760	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW47_22765	COG1360	Flagellar Motor Protein
EXW47_22770	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW47_22780	COG1876	peptidase activity
EXW47_22785	COG0824	Thioesterase
EXW47_22790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW47_22795	COG1053	succinate dehydrogenase
EXW47_22800	COG2009	succinate dehydrogenase
EXW47_22805	COG1719	4-vinyl reductase, 4VR
EXW47_22810	COG0322	excinuclease ABC activity
EXW47_22815	COG3118	belongs to the thioredoxin family
EXW47_22820	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW47_22825	COG2086	electron transfer activity
EXW47_22830	COG1024	Enoyl-CoA hydratase
EXW47_22835	COG1309	transcriptional regulator
EXW47_22840	COG0318	PFAM AMP-dependent synthetase and ligase
EXW47_22865	COG2318	DinB family
EXW47_22890	COG1131	(ABC) transporter
EXW47_22895	COG2205	protein histidine kinase activity
EXW47_22900	COG0745	RESPONSE REGULATOR receiver
EXW47_22905	COG4895	conserved protein (DUF2196)
EXW47_22910	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW47_22915	COG2329	Antibiotic biosynthesis monooxygenase
EXW47_22920	COG4509	Sortase family
EXW47_22925	COG1120	ATPase activity
EXW47_22940	COG5386	Cell surface protein
EXW47_22950	COG5386	Cell surface protein
EXW47_22955	COG1114	Component of the transport system for branched-chain amino acids
EXW47_22960	COG1187	pseudouridine synthase activity
EXW47_22965	COG1193	negative regulation of DNA recombination
EXW47_22970	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW47_22970	COG1796	DNA polymerase
EXW47_22975	COG1286	toxin biosynthetic process
EXW47_22980	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW47_22985	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW47_23010	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW47_23015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW47_23025	COG1418	mRNA catabolic process
EXW47_23055	COG2814	Major facilitator Superfamily
EXW47_23060	COG1566	PFAM secretion protein HlyD family protein
EXW47_23065	COG1309	transcriptional regulator
EXW47_23070	COG1363	Peptidase, m42
EXW47_23080	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW47_23095	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW47_23105	COG1484	DNA-dependent DNA replication
EXW47_23110	COG3611	Membrane attachment protein
EXW47_23115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW47_23120	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW47_23125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW47_23130	COG0237	dephospho-CoA kinase activity
EXW47_23135	COG1971	Probably functions as a manganese efflux pump
EXW47_23145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW47_23145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW47_23150	COG5002	protein histidine kinase activity
EXW47_23155	COG0745	RESPONSE REGULATOR receiver
EXW47_23170	COG0039	L-malate dehydrogenase activity
EXW47_23175	COG0538	isocitrate dehydrogenase activity
EXW47_23180	COG0372	Belongs to the citrate synthase family
EXW47_23195	COG0628	permease
EXW47_23200	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW47_23210	COG0205	6-phosphofructokinase activity
EXW47_23220	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW47_23225	COG1725	Transcriptional regulator
EXW47_23230	COG0281	malic enzyme
EXW47_23235	COG0587	DNA-directed DNA polymerase activity
EXW47_23250	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW47_23270	COG4109	DRTGG domain
EXW47_23280	COG0006	proline dipeptidase activity
EXW47_23310	COG0662	Cupin 2, conserved barrel domain protein
EXW47_23320	COG1476	TRANSCRIPTIONal
EXW47_23335	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_23340	COG0589	response to stress
EXW47_23370	COG0137	argininosuccinate synthase activity
EXW47_23385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW47_23405	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW47_23410	COG0827	DNA restriction-modification system
EXW47_23415	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW47_23420	COG3874	Sporulation protein YtfJ
EXW47_23435	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW47_23445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW47_23460	COG1104	cysteine desulfurase activity
EXW47_23465	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW47_23480	COG1309	transcriptional regulator
EXW47_23485	COG1956	GAF domain-containing protein
EXW47_23490	COG0626	cystathionine gamma-synthase activity
EXW47_23495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW47_23520	COG1595	DNA-templated transcription, initiation
EXW47_23530	COG0110	maltose O-acetyltransferase activity
EXW47_23535	COG0456	acetyltransferase
EXW47_23540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW47_23545	COG0454	-acetyltransferase
EXW47_23550	COG0517	IMP dehydrogenase activity
EXW47_23555	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW47_23560	COG2267	carboxylic ester hydrolase activity
EXW47_23570	COG0745	RESPONSE REGULATOR receiver
EXW47_23575	COG5002	protein histidine kinase activity
EXW47_23580	COG0666	response to abiotic stimulus
EXW47_23590	COG1970	mechanosensitive ion channel activity
EXW47_23615	COG1609	Transcriptional regulator
EXW47_23625	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW47_23625	COG1605	Chorismate mutase
EXW47_23630	COG4851	CamS sex pheromone cAM373 precursor
EXW47_23635	COG3118	belongs to the thioredoxin family
EXW47_23645	COG2309	aminopeptidase activity
EXW47_23675	COG0697	spore germination
EXW47_23680	COG0789	Transcriptional regulator
EXW47_23685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW47_23695	COG1674	ftsk spoiiie
EXW47_23710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW47_23715	COG4848	Belongs to the UPF0354 family
EXW47_23720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW47_23725	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW47_23730	COG1363	Peptidase, m42
EXW47_23740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW47_23745	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW47_23755	COG0510	thiamine kinase activity
EXW47_23760	COG1523	belongs to the glycosyl hydrolase 13 family
EXW47_23770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW47_23775	COG1349	DNA-binding transcription factor activity
EXW47_23780	COG1187	pseudouridine synthase activity
EXW47_23785	COG2244	polysaccharide biosynthetic process
EXW47_23790	COG2081	HI0933 family
EXW47_23795	COG2814	Major facilitator Superfamily
EXW47_23805	COG3832	glyoxalase III activity
EXW47_23825	COG1329	Transcriptional regulator
EXW47_23850	COG0314	molybdopterin synthase activity
EXW47_23855	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW47_23860	COG0303	'Molybdopterin
EXW47_23865	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW47_23870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW47_23875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW47_23900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW47_23910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW47_23950	COG0495	leucyl-tRNA aminoacylation
EXW47_23955	COG2814	Major facilitator Superfamily
EXW47_23960	COG0475	glutathione-regulated potassium exporter activity
EXW47_23965	COG0490	domain, Protein
EXW47_23970	COG0582	viral genome integration into host DNA
EXW47_23985	COG1136	(ABC) transporter
EXW47_24000	COG1242	4 iron, 4 sulfur cluster binding
EXW47_24005	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW47_24015	COG1131	(ABC) transporter
EXW47_24025	COG1794	racemase activity, acting on amino acids and derivatives
EXW47_24045	COG2267	carboxylic ester hydrolase activity
EXW47_24050	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW47_24055	COG0671	phosphoesterase, PA-phosphatase related
EXW47_24060	COG0438	transferase activity, transferring glycosyl groups
EXW47_24075	COG0746	molybdenum cofactor guanylyltransferase activity
EXW47_24095	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW47_24100	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW47_24140	COG5002	protein histidine kinase activity
EXW47_24145	COG3852	Histidine kinase
EXW47_24150	COG0753	catalase activity
EXW47_24155	COG2267	carboxylic ester hydrolase activity
EXW47_24165	COG1368	sulfuric ester hydrolase activity
EXW47_24175	COG4895	conserved protein (DUF2196)
EXW47_24190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW47_24195	COG1116	anion transmembrane transporter activity
EXW47_24200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW47_24225	COG0494	nUDIX hydrolase
EXW47_24265	COG2076	Multidrug Resistance protein
EXW47_24270	COG2076	Multidrug Resistance protein
EXW47_24275	COG0789	Transcriptional regulator
EXW47_24280	COG1854	S-ribosylhomocysteine lyase activity
EXW47_24290	COG0288	reversible hydration of carbon dioxide
EXW47_24295	COG1271	oxidase subunit
EXW47_24300	COG1294	oxidase, subunit
EXW47_24320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW47_24345	COG1842	Phage shock protein A
EXW47_24370	COG3859	Proton-coupled thiamine transporter YuaJ
EXW47_24375	COG5002	protein histidine kinase activity
EXW47_24380	COG0745	RESPONSE REGULATOR receiver
EXW47_24405	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW47_24410	COG1597	lipid kinase activity
EXW47_24455	COG0586	Pfam SNARE associated Golgi protein
EXW47_24460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW47_24470	COG0577	efflux transmembrane transporter activity
EXW47_24475	COG1136	(ABC) transporter
EXW47_24480	COG3708	Transcriptional regulator
EXW47_24480	COG2207	Transcriptional regulator
EXW47_24490	COG1131	(ABC) transporter
EXW47_24495	COG5658	integral membrane protein
EXW47_24500	COG0640	Transcriptional regulator
EXW47_24505	COG0745	RESPONSE REGULATOR receiver
EXW47_24510	COG2205	protein histidine kinase activity
EXW47_24515	COG0577	efflux transmembrane transporter activity
EXW47_24520	COG0577	efflux transmembrane transporter activity
EXW47_24525	COG1136	(ABC) transporter
EXW47_24530	COG0577	efflux transmembrane transporter activity
EXW47_24545	COG2188	Transcriptional regulator
EXW47_24565	COG3964	amidohydrolase
EXW47_24585	COG4948	Mandelate Racemase Muconate Lactonizing
EXW47_24590	COG0318	PFAM AMP-dependent synthetase and ligase
EXW47_24600	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW47_24610	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW47_24615	COG1169	isochorismate synthase
EXW47_24620	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW47_24625	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW47_24630	COG1278	Cold shock
EXW47_24640	COG0789	Transcriptional regulator
EXW47_24650	COG0058	SHG alpha-glucan phosphorylase activity
EXW47_24660	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW47_24670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW47_24830	COG1285	pathogenesis
EXW47_24835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW47_24845	COG0166	Belongs to the GPI family
EXW47_24855	COG2155	Conserved Protein
EXW47_24860	COG1098	S1 RNA binding domain
EXW47_24865	COG0436	Aminotransferase
EXW47_24870	COG1522	sequence-specific DNA binding
EXW47_24875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW47_24880	COG2267	carboxylic ester hydrolase activity
EXW47_24890	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW47_24905	COG5018	Exonuclease
EXW47_24910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW47_24930	COG2050	protein possibly involved in aromatic compounds catabolism
EXW47_24940	COG1268	BioY protein
EXW47_24950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW47_24955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW47_24965	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW47_24970	COG3584	3D domain protein
EXW47_24985	COG1252	NADH dehydrogenase
EXW47_24990	COG0492	ferredoxin-NADP+ reductase activity
EXW47_24995	COG3708	Transcriptional regulator
EXW47_25010	COG1683	Conserved Protein
EXW47_25035	COG0316	Belongs to the HesB IscA family
EXW47_25040	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW47_25045	COG4844	belongs to the
EXW47_25050	COG1252	NADH dehydrogenase
EXW47_25060	COG0390	transport system, permease component
EXW47_25065	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW47_25100	COG4837	Protein of unknown function (DUF1462)
EXW47_25105	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW47_25115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW47_25120	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW47_25135	COG1136	(ABC) transporter
EXW47_25135	COG0577	efflux transmembrane transporter activity
EXW47_25140	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW47_25150	COG0647	UMP catabolic process
EXW47_25160	COG2445	Protein of unknown function DUF86
EXW47_25165	COG1494	fructose-1,6-bisphosphatase
EXW47_25180	COG4470	Protein conserved in bacteria
EXW47_25190	COG0789	Transcriptional regulator
EXW47_25195	COG4377	Putative membrane peptidase family (DUF2324)
EXW47_25215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW47_25220	COG0739	heme binding
EXW47_25230	COG3377	Domain of unknown function (DUF1805)
EXW47_25235	COG0737	Belongs to the 5'-nucleotidase family
EXW47_25240	COG0719	Fe-S assembly protein
EXW47_25245	COG0822	iron-sulfur transferase activity
EXW47_25250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW47_25255	COG0719	Fe-S assembly protein
EXW47_25260	COG0396	ATPase activity
EXW47_25265	COG1464	Belongs to the NlpA lipoprotein family
EXW47_25270	COG1464	Belongs to the NlpA lipoprotein family
EXW47_25275	COG2011	ABC-type metal ion transport system permease component
EXW47_25280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW47_25290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW47_25295	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW47_25300	COG0509	glycine decarboxylation via glycine cleavage system
EXW47_25305	COG1393	Belongs to the ArsC family
EXW47_25350	COG1309	transcriptional regulator
EXW47_25355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW47_25360	COG1960	acyl-CoA dehydrogenase activity
EXW47_25365	COG0183	Belongs to the thiolase family
EXW47_25370	COG1024	Enoyl-CoA hydratase
EXW47_25370	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW47_25380	COG1686	Belongs to the peptidase S11 family
EXW47_25385	COG0506	proline dehydrogenase activity
EXW47_25395	COG0011	TIGRFAM Protein of
EXW47_25400	COG0840	transmembrane signaling receptor activity
EXW47_25415	COG2814	Major facilitator Superfamily
EXW47_25420	COG0531	amino acid
EXW47_25445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW47_25575	COG0586	Pfam SNARE associated Golgi protein
EXW47_25585	COG1376	ErfK ybiS ycfS ynhG family protein
EXW47_25590	COG0745	RESPONSE REGULATOR receiver
EXW47_25595	COG5002	protein histidine kinase activity
EXW47_25605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW47_25615	COG0840	transmembrane signaling receptor activity
EXW47_25620	COG0840	transmembrane signaling receptor activity
EXW47_25625	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW47_25630	COG3227	Zinc metalloprotease (Elastase)
EXW47_25635	COG1741	Belongs to the pirin family
EXW47_25650	COG0586	Pfam SNARE associated Golgi protein
EXW47_25655	COG0475	glutathione-regulated potassium exporter activity
EXW47_25660	COG0490	domain, Protein
EXW47_25665	COG1115	amino acid carrier protein
EXW47_25670	COG0783	Belongs to the Dps family
EXW47_25680	COG2318	DinB family
EXW47_25685	COG1611	Belongs to the LOG family
EXW47_25695	COG1528	Iron-storage protein
EXW47_25700	COG2311	Membrane
EXW47_25705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW47_25710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW47_25715	COG1115	amino acid carrier protein
EXW47_25720	COG1115	amino acid carrier protein
EXW47_25725	COG2910	NAD(P)H-binding
EXW47_25735	COG0656	L-ascorbic acid biosynthetic process
EXW47_25740	COG2814	Major facilitator Superfamily
EXW47_25745	COG1733	regulation of RNA biosynthetic process
EXW47_25755	COG1252	NADH dehydrogenase
EXW47_25775	COG0840	transmembrane signaling receptor activity
EXW47_25775	COG3290	protein histidine kinase activity
EXW47_25810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW47_25825	COG4224	UPF0291 protein
EXW47_25830	COG1335	isochorismatase
EXW47_25835	COG1522	sequence-specific DNA binding
EXW47_25845	COG1522	sequence-specific DNA binding
EXW47_25850	COG0288	reversible hydration of carbon dioxide
EXW47_25855	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW47_25860	COG2233	PERMEase
EXW47_25905	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW47_25915	COG0557	exoribonuclease II activity
EXW47_25920	COG1647	Serine aminopeptidase, S33
EXW47_25925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW47_25930	COG1346	cytolysis
EXW47_25945	COG0148	phosphopyruvate hydratase activity
EXW47_25955	COG0149	triose-phosphate isomerase activity
EXW47_25960	COG0126	phosphoglycerate kinase activity
EXW47_25965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW47_25980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW47_26015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW47_26030	COG2323	membrane
EXW47_26040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW47_26045	COG1481	regulation of sporulation
EXW47_26050	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW47_26055	COG1660	Displays ATPase and GTPase activities
EXW47_26060	COG1051	belongs to the nudix hydrolase family
EXW47_26070	COG0492	ferredoxin-NADP+ reductase activity
EXW47_26075	COG0457	Tetratricopeptide repeat
EXW47_26080	COG0110	maltose O-acetyltransferase activity
EXW47_26085	COG0546	phosphoglycolate phosphatase activity
EXW47_26090	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW47_26095	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW47_26100	COG1950	PFAM Membrane protein of
EXW47_26105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW47_26125	COG0789	Transcriptional regulator
EXW47_26160	COG0583	DNA-binding transcription factor activity
EXW47_26165	COG0789	Transcriptional regulator
EXW47_26170	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW47_26175	COG0488	(ABC) transporter
EXW47_26185	COG1132	(ABC) transporter
EXW47_26190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW47_26195	COG0793	Belongs to the peptidase S41A family
EXW47_26195	COG3409	Peptidoglycan-binding domain 1 protein
EXW47_26200	COG2177	Part of the ABC transporter FtsEX involved in
EXW47_26205	COG2884	Cell division ATP-binding protein ftsE
EXW47_26240	COG1131	(ABC) transporter
EXW47_26275	COG1278	Cold shock
EXW47_26280	COG1040	competence protein
EXW47_26285	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW47_26290	COG0791	NLP P60 protein
EXW47_26290	COG1388	LysM domain
EXW47_26295	COG1733	regulation of RNA biosynthetic process
EXW47_26300	COG1307	EDD domain protein, DegV family
EXW47_26305	COG1739	Uncharacterized protein family UPF0029
EXW47_26310	COG1316	TRANSCRIPTIONal
EXW47_26315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW47_26320	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW47_26325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW47_26335	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW47_26335	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW47_26355	COG1486	melibiose metabolic process
EXW47_26360	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW47_26365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW47_26385	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW47_26395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW47_26400	COG1301	dicarboxylic acid transport
EXW47_26420	COG1511	domain protein
EXW47_26425	COG0583	DNA-binding transcription factor activity
EXW47_26430	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW47_26435	COG1271	oxidase subunit
EXW47_26440	COG1294	oxidase, subunit
EXW47_26445	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW47_26450	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW47_26455	COG1620	l-lactate permease
EXW47_26465	COG2389	metal-binding protein
EXW47_26475	COG1368	sulfuric ester hydrolase activity
EXW47_26485	COG0791	NLP P60 protein
EXW47_26485	COG1388	LysM domain
EXW47_26490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW47_26500	COG1215	transferase activity, transferring glycosyl groups
EXW47_26505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW47_26515	COG1388	LysM domain
EXW47_26515	COG3584	3D domain protein
EXW47_26540	COG4715	Zinc finger, swim domain protein
EXW47_26545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW47_26585	COG0577	efflux transmembrane transporter activity
EXW47_26590	COG1136	(ABC) transporter
EXW47_26625	COG3850	Histidine kinase
EXW47_26625	COG5002	protein histidine kinase activity
EXW47_26630	COG0745	RESPONSE REGULATOR receiver
EXW47_26635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW47_26645	COG1316	TRANSCRIPTIONal
EXW47_26655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW47_26660	COG2244	polysaccharide biosynthetic process
EXW47_26685	COG0438	transferase activity, transferring glycosyl groups
EXW47_26690	COG1045	serine acetyltransferase
EXW47_26695	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW47_26700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW47_26705	COG1086	Polysaccharide biosynthesis protein
EXW47_26710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW47_26715	COG4464	protein tyrosine phosphatase activity
EXW47_26720	COG0489	protein tyrosine kinase activity
EXW47_26725	COG3944	biosynthesis protein
EXW47_26730	COG0489	protein tyrosine kinase activity
EXW47_26745	COG1609	Transcriptional regulator
EXW47_26755	COG0739	heme binding
EXW47_26770	COG3279	Response regulator of the LytR AlgR family
EXW47_26775	COG2385	sporulation resulting in formation of a cellular spore
EXW47_26790	COG4836	Membrane
EXW47_26795	COG1007	ATP synthesis coupled electron transport
EXW47_26800	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW47_26805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW47_26810	COG0713	ATP synthesis coupled electron transport
EXW47_26815	COG0839	Belongs to the complex I subunit 6 family
EXW47_26825	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW47_26830	COG0649	NAD binding
EXW47_26835	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW47_26840	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW47_26845	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW47_26850	COG3300	MHYT domain
EXW47_26850	COG5001	Diguanylate cyclase
EXW47_26865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW47_26870	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW47_26875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW47_26880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW47_26885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW47_26890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW47_26900	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW47_26925	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW47_26935	COG0698	ribose 5-phosphate isomerase
EXW47_26945	COG2190	(PTS) system
EXW47_26950	COG2259	Doxx family
EXW47_26955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW47_26970	COG1971	Probably functions as a manganese efflux pump
EXW47_26975	COG0009	L-threonylcarbamoyladenylate synthase
EXW47_26990	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW47_26995	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW47_27000	COG1435	thymidine kinase activity
EXW47_27010	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW47_27020	COG1494	fructose-1,6-bisphosphatase
EXW47_27040	COG4821	SIS domain
EXW47_27045	COG0504	CTP synthase activity
EXW47_27050	COG3343	RNA polymerase activity
EXW47_27060	COG1960	acyl-CoA dehydrogenase activity
EXW47_27065	COG1960	acyl-CoA dehydrogenase activity
EXW47_27070	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW47_27075	COG0183	Belongs to the thiolase family
EXW47_27080	COG0247	lactate metabolic process
EXW47_27080	COG2181	nitrate reductase activity
EXW47_27085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW47_27090	COG4294	response to UV
EXW47_27095	COG3300	MHYT domain
EXW47_27095	COG5001	Diguanylate cyclase
EXW47_27110	COG3227	Zinc metalloprotease (Elastase)
EXW47_27115	COG2197	response regulator
EXW47_27120	COG4585	Histidine kinase
EXW47_27125	COG0842	Transport permease protein
EXW47_27130	COG1131	(ABC) transporter
EXW47_27135	COG0024	Methionine aminopeptidase
EXW47_27140	COG2234	aminopeptidase activity
EXW47_27155	COG4506	Protein conserved in bacteria
EXW47_27160	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW47_27175	COG0010	Belongs to the arginase family
EXW47_27180	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW47_27185	COG2814	Major facilitator Superfamily
EXW47_27190	COG0789	Transcriptional regulator
EXW47_27195	COG0584	glycerophosphoryl diester phosphodiesterase
EXW47_27200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW47_27210	COG1994	Peptidase M50
EXW47_27220	COG1078	dGTPase activity
EXW47_27225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW47_27230	COG1120	ATPase activity
EXW47_27235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW47_27240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW47_27245	COG4844	belongs to the
EXW47_27260	COG0280	phosphate acetyltransferase
EXW47_27265	COG3253	May function as heme-dependent peroxidase
EXW47_27275	COG3773	Cell wall hydrolase
EXW47_27285	COG2363	Small membrane protein
EXW47_27300	COG2233	PERMEase
EXW47_27305	COG0561	phosphatase activity
EXW47_27310	COG2814	Major facilitator Superfamily
EXW47_27315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW47_27320	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW47_27325	COG1131	(ABC) transporter
EXW47_27330	COG2755	lipolytic protein G-D-S-L family
EXW47_27335	COG1609	Transcriptional regulator
EXW47_27345	COG0460	homoserine dehydrogenase
EXW47_27350	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW47_27355	COG2873	o-acetylhomoserine
EXW47_27375	COG2197	response regulator
EXW47_27380	COG4585	Histidine kinase
EXW47_27380	COG2203	Gaf domain
EXW47_27385	COG0351	phosphomethylpyrimidine kinase
EXW47_27390	COG3706	GGDEF domain
EXW47_27395	COG2879	small protein
EXW47_27400	COG1966	Carbon starvation protein
EXW47_27405	COG3279	Response regulator of the LytR AlgR family
EXW47_27410	COG0477	Major facilitator Superfamily
EXW47_27435	COG0840	transmembrane signaling receptor activity
EXW47_27445	COG1607	acyl-coa hydrolase
EXW47_27450	COG1216	Glycosyl transferase, family 2
EXW47_27460	COG1216	Glycosyl transferase, family 2
EXW47_27470	COG0488	(ABC) transporter
EXW47_27475	COG1696	Membrane protein involved in D-alanine export
EXW47_27485	COG1309	transcriptional regulator
EXW47_27490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW47_27495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW47_27495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW47_27500	COG0628	permease
EXW47_27510	COG1380	Effector of murein hydrolase LrgA
EXW47_27515	COG3279	Response regulator of the LytR AlgR family
EXW47_27520	COG3275	phosphorelay sensor kinase activity
EXW47_27525	COG2814	Major facilitator Superfamily
EXW47_27530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW47_27535	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW47_27545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW47_27595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW47_27600	COG1272	protein, Hemolysin III
EXW47_27630	COG1164	Oligoendopeptidase f
EXW47_27640	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW47_27650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW47_27655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW47_27660	COG4853	Protein conserved in bacteria
EXW47_27670	COG5002	protein histidine kinase activity
EXW47_27675	COG0745	RESPONSE REGULATOR receiver
EXW47_27705	COG0305	Participates in initiation and elongation during chromosome replication
EXW47_27710	COG0359	binds to the 23S rRNA
EXW47_27715	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW47_27720	COG4241	membrane
EXW47_27730	COG0629	single-stranded DNA binding
EXW47_27735	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW47_27740	COG0012	GTP binding
EXW47_27745	COG4481	Protein conserved in bacteria
EXW47_27750	COG0668	transmembrane transport
EXW47_27760	COG1475	DNA binding
EXW47_27765	COG1192	Involved in chromosome partitioning
EXW47_27770	COG1475	DNA binding
EXW47_27775	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW47_27780	COG0445	tRNA wobble uridine modification
EXW47_27785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW47_27790	COG1847	R3H domain protein
EXW47_27795	COG0706	membrane insertase activity
EXW47_27800	COG0594	ribonuclease P activity
EXW47_27805	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW47_27825	COG1028	Short-chain dehydrogenase reductase Sdr
EXW47_27880	COG0673	inositol 2-dehydrogenase activity
EXW47_27885	COG0673	inositol 2-dehydrogenase activity
EXW47_27890	COG2169	Transcriptional regulator
EXW47_28140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW47_28150	COG0662	Cupin 2, conserved barrel domain protein
EXW47_28150	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EXW47_28215	COG3344	reverse transcriptase
EXW47_28240	COG2311	Membrane
EXW47_28275	COG1696	Membrane protein involved in D-alanine export
EXW47_28295	COG0745	RESPONSE REGULATOR receiver
EXW47_28320	COG1279	arginine transmembrane transporter activity
EXW47_28325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW47_28330	COG1175	transmembrane transport
EXW47_28335	COG0395	ABC-type sugar transport system, permease component
EXW47_28360	COG3842	ATPase activity
EXW47_28365	COG5002	protein histidine kinase activity
EXW47_28375	COG1136	(ABC) transporter
EXW47_28390	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW47_28400	COG2707	UPF0756 membrane protein
EXW47_28410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW47_28545	COG2814	Major facilitator Superfamily
EXW47_28600	COG0640	Transcriptional regulator
EXW47_28630	COG5658	integral membrane protein
EXW47_28640	COG1733	regulation of RNA biosynthetic process
EXW47_28650	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EXW47_28660	COG2918	glutathione biosynthetic process
EXW47_28660	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW47_28670	COG0583	DNA-binding transcription factor activity
EXW47_28780	COG4977	sequence-specific DNA binding
EXW47_28795	COG0083	homoserine kinase activity
EXW47_28815	COG1309	transcriptional regulator
EXW47_28820	COG2814	Major facilitator Superfamily
EXW47_28830	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW47_28830	COG2508	Transcriptional regulator
EXW47_28835	COG0686	Belongs to the AlaDH PNT family
EXW47_28905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW47_28960	COG1396	sequence-specific DNA binding
EXW47_28980	COG0840	transmembrane signaling receptor activity
EXW47_28985	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW47_29005	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW47_29010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW47_29015	COG0772	Belongs to the SEDS family
EXW47_29020	COG2239	Acts as a magnesium transporter
EXW47_29030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW47_29045	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW47_29050	COG0519	Catalyzes the synthesis of GMP from XMP
EXW47_29060	COG1278	Cold shock
EXW47_29080	COG0024	Methionine aminopeptidase
EXW47_29115	COG4974	Belongs to the 'phage' integrase family
EXW47_29215	COG2357	RelA SpoT domain protein
EXW47_29220	COG2814	Major facilitator Superfamily
EXW47_29275	COG0776	regulation of translation
EXW47_29315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW47_29335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW47_29360	COG3344	reverse transcriptase
EXW47_29410	COG0640	Transcriptional regulator
EXW47_29425	COG0457	Tetratricopeptide repeat
EXW47_29475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW47_29485	COG2040	homocysteine
EXW47_29490	COG0833	amino acid
EXW47_29590	COG1725	Transcriptional regulator
EXW47_29595	COG1131	(ABC) transporter
EXW47_29640	COG1329	Transcriptional regulator
EXW47_29710	COG0457	Tetratricopeptide repeat
EXW47_29740	COG1132	(ABC) transporter
EXW47_29785	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW47_29795	COG0494	nUDIX hydrolase
EXW47_29815	COG1396	sequence-specific DNA binding
EXW47_29845	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW47_29910	COG0457	Tetratricopeptide repeat
EXW47_29980	COG0367	asparagine synthase
EXW47_30070	COG0542	response to heat
EXW47_30080	COG3397	chitin binding
EXW47_30155	COG1132	(ABC) transporter
EXW47_30210	COG1404	Belongs to the peptidase S8 family
EXW47_30220	COG2814	Major facilitator Superfamily
EXW47_30225	COG2234	aminopeptidase activity
EXW47_30235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW47_30250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW47_30255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW47_30260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW47_30270	COG0456	acetyltransferase