locus-tag	class	description
EXW43_00020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW43_00045	COG1404	Belongs to the peptidase S8 family
EXW43_00200	COG1695	Transcriptional regulator
EXW43_00285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW43_00285	COG0551	DNA topoisomerase type I activity
EXW43_00325	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW43_00365	COG0463	Glycosyl transferase, family 2
EXW43_00445	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW43_00450	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW43_00455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW43_00460	COG0438	transferase activity, transferring glycosyl groups
EXW43_00485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW43_00490	COG0438	transferase activity, transferring glycosyl groups
EXW43_00495	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW43_00580	COG3773	Cell wall hydrolase
EXW43_00670	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW43_00680	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW43_00695	COG0714	Associated with various cellular activities
EXW43_00730	COG4166	transmembrane transport
EXW43_00775	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW43_00780	COG0592	DNA-directed DNA polymerase activity
EXW43_00785	COG2501	S4 domain
EXW43_00790	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW43_00795	COG0187	DNA topoisomerase II activity
EXW43_00800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW43_00835	COG0517	IMP dehydrogenase activity
EXW43_00835	COG0516	GMP reductase activity
EXW43_00840	COG1686	Belongs to the peptidase S11 family
EXW43_00845	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW43_00850	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW43_00870	COG1428	Deoxynucleoside kinase
EXW43_00875	COG1428	Deoxynucleoside kinase
EXW43_00880	COG1335	isochorismatase
EXW43_00885	COG0590	tRNA wobble adenosine to inosine editing
EXW43_00895	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW43_00900	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW43_00905	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW43_00950	COG1982	Orn Lys Arg decarboxylase major
EXW43_00955	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW43_00960	COG0470	DNA polymerase III
EXW43_00965	COG1774	PSP1 C-terminal conserved region
EXW43_00970	COG4467	Involved in initiation control of chromosome replication
EXW43_00975	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW43_00985	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW43_00990	COG2002	toxin-antitoxin pair type II binding
EXW43_01000	COG0084	hydrolase, TatD family'
EXW43_01010	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW43_01020	COG4466	Protein conserved in bacteria
EXW43_01030	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW43_01035	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW43_01040	COG0251	oxidation-reduction process
EXW43_01045	COG2088	sporulation resulting in formation of a cellular spore
EXW43_01050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW43_01070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW43_01075	COG2002	toxin-antitoxin pair type II binding
EXW43_01080	COG2244	polysaccharide biosynthetic process
EXW43_01085	COG3956	TIGRFAM MazG family protein
EXW43_01090	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW43_01110	COG1098	S1 RNA binding domain
EXW43_01125	COG2208	phosphoserine phosphatase activity
EXW43_01135	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW43_01140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW43_01145	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW43_01150	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW43_01155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW43_01160	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW43_01165	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW43_01170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW43_01175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW43_01180	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW43_01185	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW43_01190	COG1396	sequence-specific DNA binding
EXW43_01195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW43_01200	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW43_01285	COG3880	PFAM UvrB UvrC protein
EXW43_01290	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW43_01295	COG0542	response to heat
EXW43_01300	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW43_01305	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW43_01310	COG4956	integral membrane protein (PIN domain superfamily)
EXW43_01315	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW43_01325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW43_01330	COG1045	serine acetyltransferase
EXW43_01335	COG0215	cysteine-tRNA ligase activity
EXW43_01345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW43_01350	COG3688	RNA-binding protein containing a PIN domain
EXW43_01360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW43_01365	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW43_01370	COG0250	Participates in transcription elongation, termination and antitermination
EXW43_01375	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW43_01380	COG0081	regulation of translation
EXW43_01385	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW43_01390	COG0222	ribosome binding
EXW43_01395	COG2813	Specifically methylates the guanine in position
EXW43_01400	COG0085	RNA polymerase activity
EXW43_01405	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW43_01410	COG1358	cellular component organization or biogenesis
EXW43_01415	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW43_01425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW43_01430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW43_01435	COG0051	transcription antitermination factor activity, RNA binding
EXW43_01440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW43_01445	COG0088	Forms part of the polypeptide exit tunnel
EXW43_01450	COG0089	rRNA binding
EXW43_01455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW43_01460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW43_01465	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW43_01480	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW43_01485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW43_01495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW43_01500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW43_01510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW43_01520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW43_01530	COG1841	ribosomal large subunit assembly
EXW43_01535	COG0200	Binds to the 23S rRNA
EXW43_01540	COG0201	protein transport
EXW43_01545	COG0563	adenylate kinase activity
EXW43_01550	COG0024	Methionine aminopeptidase
EXW43_01560	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW43_01565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW43_01570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW43_01595	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW43_01605	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW43_01610	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW43_01620	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW43_01625	COG0489	protein tyrosine kinase activity
EXW43_01635	COG2194	sulfuric ester hydrolase activity
EXW43_01640	COG0726	polysaccharide deacetylase
EXW43_01720	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW43_01725	COG4856	YbbR-like protein
EXW43_01730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW43_01760	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_01765	COG2011	ABC-type metal ion transport system permease component
EXW43_01775	COG1464	Belongs to the NlpA lipoprotein family
EXW43_01790	COG0277	FAD linked oxidase domain protein
EXW43_01795	COG2271	Major facilitator Superfamily
EXW43_01805	COG2814	Major facilitator Superfamily
EXW43_01820	COG0601	transmembrane transport
EXW43_01825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW43_01830	COG0444	Belongs to the ABC transporter superfamily
EXW43_01835	COG4608	Belongs to the ABC transporter superfamily
EXW43_01840	COG4166	transmembrane transport
EXW43_01850	COG2207	Transcriptional regulator
EXW43_01865	COG4166	transmembrane transport
EXW43_01870	COG4166	transmembrane transport
EXW43_01875	COG0656	L-ascorbic acid biosynthetic process
EXW43_01880	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW43_01895	COG4149	molybdate abc transporter
EXW43_01900	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW43_01905	COG1910	domain protein
EXW43_01920	COG0697	spore germination
EXW43_01935	COG0204	Acyl-transferase
EXW43_01945	COG1609	Transcriptional regulator
EXW43_01955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW43_01970	COG5298	Protein conserved in bacteria
EXW43_01995	COG0488	(ABC) transporter
EXW43_02000	COG4585	Histidine kinase
EXW43_02005	COG2197	response regulator
EXW43_02010	COG1131	(ABC) transporter
EXW43_02015	COG0842	Transport permease protein
EXW43_02015	COG1511	domain protein
EXW43_02020	COG0842	Transport permease protein
EXW43_02030	COG0747	negative chemotaxis
EXW43_02040	COG0601	transmembrane transport
EXW43_02045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW43_02050	COG0444	Belongs to the ABC transporter superfamily
EXW43_02055	COG4608	Belongs to the ABC transporter superfamily
EXW43_02060	COG0561	phosphatase activity
EXW43_02090	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW43_02095	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW43_02105	COG0531	amino acid
EXW43_02110	COG2814	Major facilitator Superfamily
EXW43_02120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW43_02130	COG4294	response to UV
EXW43_02135	COG0705	Rhomboid family
EXW43_02140	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW43_02145	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW43_02155	COG0864	Transcriptional regulator
EXW43_02160	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW43_02165	COG2183	response to ionizing radiation
EXW43_02265	COG0802	atpase or kinase
EXW43_02270	COG1214	PFAM Peptidase M22, glycoprotease
EXW43_02275	COG0456	acetyltransferase
EXW43_02285	COG0488	(ABC) transporter
EXW43_02290	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW43_02300	COG1266	CAAX protease self-immunity
EXW43_02305	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW43_02310	COG0459	protein refolding
EXW43_02315	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW43_02315	COG0519	Catalyzes the synthesis of GMP from XMP
EXW43_02320	COG2252	PERMEase
EXW43_02330	COG5002	protein histidine kinase activity
EXW43_02355	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW43_02420	COG2205	protein histidine kinase activity
EXW43_02425	COG0745	RESPONSE REGULATOR receiver
EXW43_02450	COG0697	spore germination
EXW43_02480	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW43_02485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW43_02490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW43_02495	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW43_02500	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW43_02505	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW43_02510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW43_02515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW43_02520	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW43_02525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW43_02530	COG0138	bifunctional purine biosynthesis protein purh
EXW43_02535	COG0151	Belongs to the GarS family
EXW43_02555	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW43_02560	COG0210	DNA helicase
EXW43_02565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW43_02570	COG4851	CamS sex pheromone cAM373 precursor
EXW43_02580	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_02585	COG1335	isochorismatase
EXW43_02595	COG2011	ABC-type metal ion transport system permease component
EXW43_02600	COG1464	Belongs to the NlpA lipoprotein family
EXW43_02615	COG0003	Pfam Anion-transporting ATPase
EXW43_02620	COG1846	Transcriptional regulator
EXW43_02625	COG4682	membrane
EXW43_02635	COG0154	amidase activity
EXW43_02640	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW43_02645	COG1597	lipid kinase activity
EXW43_02650	COG0546	phosphoglycolate phosphatase activity
EXW43_02655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW43_02665	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_02670	COG2076	Multidrug Resistance protein
EXW43_02675	COG2309	aminopeptidase activity
EXW43_02690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW43_02700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW43_02705	COG5002	protein histidine kinase activity
EXW43_02710	COG4807	Protein conserved in bacteria
EXW43_02735	COG1757	Na H antiporter
EXW43_02740	COG1473	amidohydrolase
EXW43_02755	COG0450	alkyl hydroperoxide reductase
EXW43_02765	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW43_02775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW43_02780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW43_02785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW43_02795	COG0492	ferredoxin-NADP+ reductase activity
EXW43_02810	COG0166	Belongs to the GPI family
EXW43_02835	COG5002	protein histidine kinase activity
EXW43_02855	COG3541	Predicted nucleotidyltransferase
EXW43_02860	COG2814	Major facilitator Superfamily
EXW43_02865	COG0723	plastoquinol--plastocyanin reductase activity
EXW43_02865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW43_02875	COG0765	amino acid transport
EXW43_02880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW43_02890	COG0840	transmembrane signaling receptor activity
EXW43_02895	COG0277	FAD linked oxidase domain protein
EXW43_02900	COG0366	Alpha amylase catalytic
EXW43_02905	COG1263	PTS System
EXW43_02905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW43_02905	COG2190	(PTS) system
EXW43_02925	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW43_02930	COG0352	thiamine-phosphate diphosphorylase activity
EXW43_02935	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW43_02950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW43_02955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW43_02960	COG1116	anion transmembrane transporter activity
EXW43_02965	COG0488	(ABC) transporter
EXW43_03010	COG2270	Major facilitator Superfamily
EXW43_03040	COG2310	stress, protein
EXW43_03045	COG2310	stress, protein
EXW43_03050	COG2310	stress, protein
EXW43_03055	COG0861	Integral membrane protein TerC family
EXW43_03065	COG3853	Toxic anion resistance protein (TelA)
EXW43_03075	COG4840	Belongs to the UPF0435 family
EXW43_03080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW43_03090	COG1295	ribonuclease BN
EXW43_03095	COG2217	Heavy metal translocating P-type atpase
EXW43_03100	COG0697	spore germination
EXW43_03125	COG0586	Pfam SNARE associated Golgi protein
EXW43_03140	COG3871	stress protein (general stress protein 26)
EXW43_03145	COG0387	Pfam Sodium calcium exchanger
EXW43_03155	COG0535	radical SAM domain protein
EXW43_03175	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW43_03195	COG3829	transcription factor binding
EXW43_03205	COG0833	amino acid
EXW43_03210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW43_03230	COG2066	Belongs to the glutaminase family
EXW43_03240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW43_03240	COG1263	PTS System
EXW43_03245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW43_03260	COG1216	Glycosyl transferase, family 2
EXW43_03270	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW43_03270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW43_03275	COG0463	Glycosyl transferase, family 2
EXW43_03290	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW43_03295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW43_03310	COG1228	amidohydrolase
EXW43_03315	COG1090	epimerase
EXW43_03320	COG2137	regulation of response to DNA damage stimulus
EXW43_03345	COG1988	membrane-bound metal-dependent
EXW43_03350	COG1194	a g-specific adenine glycosylase
EXW43_03365	COG3557	Belongs to the UPF0374 family
EXW43_03370	COG1132	(ABC) transporter
EXW43_03375	COG4129	membrane
EXW43_03385	COG0070	glutamate synthase
EXW43_03385	COG0069	glutamate synthase activity
EXW43_03385	COG0067	glutamate synthase
EXW43_03390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW43_03395	COG4555	ABC transporter
EXW43_03415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW43_03420	COG0735	belongs to the Fur family
EXW43_03535	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW43_03540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW43_03560	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW43_03565	COG1716	ATPase activity
EXW43_03565	COG5001	Diguanylate cyclase
EXW43_03570	COG2766	serine protein kinase
EXW43_03575	COG2718	Belongs to the UPF0229 family
EXW43_03625	COG1132	(ABC) transporter
EXW43_03630	COG1132	(ABC) transporter
EXW43_03635	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW43_03660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW43_03690	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW43_03695	COG2268	Band 7 protein
EXW43_03705	COG3290	protein histidine kinase activity
EXW43_03710	COG4565	transcriptional regulatory protein
EXW43_03715	COG2851	Citrate transporter
EXW43_03740	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW43_03745	COG3842	ATPase activity
EXW43_03750	COG1175	transmembrane transport
EXW43_03755	COG0395	ABC-type sugar transport system, permease component
EXW43_03765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW43_03770	COG0745	RESPONSE REGULATOR receiver
EXW43_03775	COG5002	protein histidine kinase activity
EXW43_03785	COG4990	cell redox homeostasis
EXW43_03795	COG3290	protein histidine kinase activity
EXW43_03800	COG4565	transcriptional regulatory protein
EXW43_03805	COG3493	citrate carrier protein
EXW43_03810	COG0281	malic enzyme
EXW43_03820	COG0697	spore germination
EXW43_03825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW43_03835	COG5002	protein histidine kinase activity
EXW43_03840	COG0745	RESPONSE REGULATOR receiver
EXW43_03845	COG0456	acetyltransferase
EXW43_03850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW43_03855	COG3383	formate dehydrogenase (NAD+) activity
EXW43_03860	COG2427	Protein of unknown function (DUF1641)
EXW43_03875	COG0531	amino acid
EXW43_03885	COG0640	Transcriptional regulator
EXW43_03890	COG2217	Heavy metal translocating P-type atpase
EXW43_03895	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW43_03905	COG3227	Zinc metalloprotease (Elastase)
EXW43_03925	COG2720	vancomycin resistance protein
EXW43_03930	COG1316	TRANSCRIPTIONal
EXW43_03935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW43_03940	COG0346	lactoylglutathione lyase activity
EXW43_03945	COG1253	flavin adenine dinucleotide binding
EXW43_03950	COG1027	Aspartate ammonia-lyase
EXW43_03955	COG1620	l-lactate permease
EXW43_03960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW43_03980	COG3104	oligopeptide transport
EXW43_03985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW43_03990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW43_03995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW43_04010	COG0156	8-amino-7-oxononanoate synthase activity
EXW43_04015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW43_04025	COG4548	von Willebrand factor, type A
EXW43_04030	COG0714	Associated with various cellular activities
EXW43_04050	COG0531	amino acid
EXW43_04055	COG2188	Transcriptional regulator
EXW43_04060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW43_04060	COG1263	PTS System
EXW43_04065	COG0366	Alpha amylase catalytic
EXW43_04080	COG0697	spore germination
EXW43_04085	COG4585	Histidine kinase
EXW43_04090	COG2197	response regulator
EXW43_04095	COG1404	Belongs to the peptidase S8 family
EXW43_04110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW43_04115	COG1115	amino acid carrier protein
EXW43_04120	COG1126	abc transporter atp-binding protein
EXW43_04125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW43_04130	COG0765	amino acid transport
EXW43_04135	COG0765	amino acid transport
EXW43_04140	COG0833	amino acid
EXW43_04165	COG2378	regulation of single-species biofilm formation
EXW43_04170	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW43_04175	COG5002	protein histidine kinase activity
EXW43_04190	COG0659	secondary active sulfate transmembrane transporter activity
EXW43_04205	COG2271	Major facilitator Superfamily
EXW43_04210	COG1846	Transcriptional regulator
EXW43_04215	COG0477	Major facilitator Superfamily
EXW43_04220	COG1609	Transcriptional regulator
EXW43_04225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW43_04230	COG1869	D-ribose catabolic process
EXW43_04240	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW43_04245	COG1879	ABC-type sugar transport system periplasmic component
EXW43_04275	COG1063	alcohol dehydrogenase
EXW43_04290	COG3568	Endonuclease Exonuclease Phosphatase
EXW43_04320	COG0840	transmembrane signaling receptor activity
EXW43_04325	COG1388	LysM domain
EXW43_04325	COG3584	3D domain protein
EXW43_04330	COG1476	TRANSCRIPTIONal
EXW43_04350	COG3104	oligopeptide transport
EXW43_04355	COG1114	Component of the transport system for branched-chain amino acids
EXW43_04370	COG1113	amino acid transport
EXW43_04375	COG2252	PERMEase
EXW43_04390	COG2153	protein acetylation
EXW43_04400	COG0569	domain protein
EXW43_04400	COG0475	glutathione-regulated potassium exporter activity
EXW43_04415	COG1845	cytochrome c oxidase, subunit III
EXW43_04420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW43_04430	COG0833	amino acid
EXW43_04435	COG4990	cell redox homeostasis
EXW43_04450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW43_04455	COG0697	spore germination
EXW43_04460	COG0531	amino acid
EXW43_04470	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW43_04475	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW43_04485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW43_04490	COG0573	inorganic phosphate transmembrane transporter activity
EXW43_04495	COG0581	inorganic phosphate transmembrane transporter activity
EXW43_04505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW43_04625	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW43_04640	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW43_04640	COG4991	sh3 domain protein
EXW43_04640	COG3103	Sh3 type 3 domain protein
EXW43_04645	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW43_04650	COG1116	anion transmembrane transporter activity
EXW43_04655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW43_04660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW43_04665	COG0352	thiamine-phosphate diphosphorylase activity
EXW43_04670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW43_04675	COG2104	thiamine diphosphate biosynthetic process
EXW43_04680	COG2022	thiamine diphosphate biosynthetic process
EXW43_04685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW43_04690	COG0351	phosphomethylpyrimidine kinase
EXW43_04715	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW43_04720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW43_04725	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW43_04730	COG2205	protein histidine kinase activity
EXW43_04735	COG2814	Major facilitator Superfamily
EXW43_04740	COG1846	Transcriptional regulator
EXW43_04760	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW43_04765	COG1129	ABC transporter
EXW43_04770	COG1879	ABC-type sugar transport system periplasmic component
EXW43_04775	COG2252	PERMEase
EXW43_04780	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_04795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW43_04800	COG1621	beta-fructofuranosidase activity
EXW43_04805	COG1263	PTS System
EXW43_04805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW43_04810	COG1609	Transcriptional regulator
EXW43_04860	COG0778	Nitroreductase
EXW43_04865	COG2719	SpoVR family
EXW43_04890	COG1937	Protein conserved in bacteria
EXW43_04895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW43_04895	COG0425	Belongs to the sulfur carrier protein TusA family
EXW43_04900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW43_04900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW43_04905	COG0425	Belongs to the sulfur carrier protein TusA family
EXW43_04910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW43_04910	COG0425	Belongs to the sulfur carrier protein TusA family
EXW43_04915	COG2210	Belongs to the sulfur carrier protein TusA family
EXW43_04920	COG0730	response to heat
EXW43_04930	COG1316	TRANSCRIPTIONal
EXW43_04935	COG0604	alcohol dehydrogenase
EXW43_04940	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW43_04945	COG0604	alcohol dehydrogenase
EXW43_04950	COG2814	Major facilitator Superfamily
EXW43_04965	COG3711	transcriptional antiterminator
EXW43_04965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW43_04970	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW43_04975	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW43_05000	COG3584	3D domain protein
EXW43_05000	COG1388	LysM domain
EXW43_05005	COG0577	efflux transmembrane transporter activity
EXW43_05010	COG1136	(ABC) transporter
EXW43_05020	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW43_05035	COG1114	Component of the transport system for branched-chain amino acids
EXW43_05040	COG3546	catalase activity
EXW43_05070	COG0586	Pfam SNARE associated Golgi protein
EXW43_05100	COG0531	amino acid
EXW43_05105	COG0475	glutathione-regulated potassium exporter activity
EXW43_05115	COG1737	Transcriptional regulator
EXW43_05120	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW43_05125	COG1263	PTS System
EXW43_05125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW43_05135	COG2259	Doxx family
EXW43_05155	COG0697	spore germination
EXW43_05160	COG1522	sequence-specific DNA binding
EXW43_05170	COG0300	oxidoreductase activity
EXW43_05185	COG2076	Multidrug Resistance protein
EXW43_05190	COG1309	transcriptional regulator
EXW43_05195	COG2814	Major facilitator Superfamily
EXW43_05200	COG1733	regulation of RNA biosynthetic process
EXW43_05215	COG4533	DNA binding
EXW43_05220	COG2211	Major facilitator Superfamily
EXW43_05230	COG0693	protein deglycase activity
EXW43_05240	COG0531	amino acid
EXW43_05245	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_05260	COG1132	(ABC) transporter
EXW43_05265	COG1132	(ABC) transporter
EXW43_05270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW43_05275	COG0765	amino acid transport
EXW43_05280	COG1126	abc transporter atp-binding protein
EXW43_05295	COG0189	ligase activity
EXW43_05305	COG4399	Belongs to the UPF0754 family
EXW43_05310	COG3679	Belongs to the UPF0342 family
EXW43_05325	COG0028	Belongs to the TPP enzyme family
EXW43_05330	COG3527	Alpha-acetolactate decarboxylase
EXW43_05335	COG0463	Glycosyl transferase, family 2
EXW43_05340	COG1216	Glycosyl transferase, family 2
EXW43_05345	COG2094	Belongs to the DNA glycosylase MPG family
EXW43_05350	COG0561	phosphatase activity
EXW43_05360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW43_05365	COG0318	PFAM AMP-dependent synthetase and ligase
EXW43_05375	COG0659	secondary active sulfate transmembrane transporter activity
EXW43_05385	COG2244	polysaccharide biosynthetic process
EXW43_05405	COG1696	Membrane protein involved in D-alanine export
EXW43_05420	COG1024	Enoyl-CoA hydratase
EXW43_05435	COG1363	Peptidase, m42
EXW43_05450	COG2318	DinB family
EXW43_05470	COG0579	oxidoreductase
EXW43_05505	COG0601	transmembrane transport
EXW43_05510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW43_05515	COG0444	Belongs to the ABC transporter superfamily
EXW43_05520	COG4608	Belongs to the ABC transporter superfamily
EXW43_05575	COG5444	nuclease activity
EXW43_05605	COG0477	Major facilitator Superfamily
EXW43_05610	COG3290	protein histidine kinase activity
EXW43_05615	COG4565	transcriptional regulatory protein
EXW43_05620	COG3181	Tripartite tricarboxylate transporter family receptor
EXW43_05635	COG1074	ATP-dependent DNA helicase activity
EXW43_05715	COG0305	Participates in initiation and elongation during chromosome replication
EXW43_05745	COG0477	Major facilitator Superfamily
EXW43_05835	COG2814	Major facilitator Superfamily
EXW43_05840	COG0640	Transcriptional regulator
EXW43_05860	COG2376	Dihydroxyacetone kinase
EXW43_05875	COG2376	Dihydroxyacetone kinase
EXW43_05890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW43_05905	COG1335	isochorismatase
EXW43_05910	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW43_05930	COG0076	glutamate decarboxylase activity
EXW43_05955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW43_05960	COG1278	Cold shock
EXW43_05970	COG2409	Drug exporters of the RND superfamily
EXW43_05995	COG3237	CsbD-like
EXW43_06015	COG2172	sigma factor antagonist activity
EXW43_06020	COG1191	sigma factor activity
EXW43_06030	COG2208	phosphoserine phosphatase activity
EXW43_06035	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW43_06040	COG0784	Response regulator, receiver
EXW43_06040	COG2205	protein histidine kinase activity
EXW43_06040	COG5002	protein histidine kinase activity
EXW43_06065	COG2807	transmembrane transport
EXW43_06070	COG2186	Transcriptional regulator
EXW43_06075	COG4585	Histidine kinase
EXW43_06080	COG2197	response regulator
EXW43_06110	COG0420	3'-5' exonuclease activity
EXW43_06115	COG4717	serine-type aminopeptidase activity
EXW43_06120	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW43_06130	COG0346	lactoylglutathione lyase activity
EXW43_06135	COG0346	lactoylglutathione lyase activity
EXW43_06150	COG2267	carboxylic ester hydrolase activity
EXW43_06160	COG2140	Oxalate decarboxylase
EXW43_06165	COG3620	sequence-specific DNA binding
EXW43_06170	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW43_06175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW43_06180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW43_06185	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW43_06190	COG1695	Transcriptional regulator
EXW43_06200	COG1595	DNA-templated transcription, initiation
EXW43_06215	COG3973	AAA domain
EXW43_06220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW43_06235	COG1846	Transcriptional regulator
EXW43_06245	COG0537	adenosine 5'-monophosphoramidase activity
EXW43_06250	COG1131	(ABC) transporter
EXW43_06255	COG4473	ABC transporter
EXW43_06265	COG0247	lactate metabolic process
EXW43_06270	COG1139	Iron-sulfur cluster binding protein
EXW43_06275	COG1556	Lactate utilization protein
EXW43_06290	COG3402	PFAM membrane-flanked domain
EXW43_06295	COG3428	Bacterial PH domain
EXW43_06335	COG3402	PFAM membrane-flanked domain
EXW43_06340	COG3428	Bacterial PH domain
EXW43_06345	COG2329	Antibiotic biosynthesis monooxygenase
EXW43_06350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW43_06355	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW43_06360	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW43_06365	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW43_06390	COG1309	transcriptional regulator
EXW43_06395	COG1511	domain protein
EXW43_06430	COG2378	regulation of single-species biofilm formation
EXW43_06435	COG1609	Transcriptional regulator
EXW43_06445	COG1234	tRNA 3'-trailer cleavage
EXW43_06450	COG0095	Lipoate-protein ligase
EXW43_06460	COG0318	PFAM AMP-dependent synthetase and ligase
EXW43_06475	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW43_06480	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW43_06485	COG4208	sulfate ABC transporter
EXW43_06500	COG1408	metallophosphoesterase
EXW43_06505	COG1078	dGTPase activity
EXW43_06520	COG1595	DNA-templated transcription, initiation
EXW43_06530	COG2207	Transcriptional regulator
EXW43_06530	COG3708	Transcriptional regulator
EXW43_06535	COG2205	protein histidine kinase activity
EXW43_06540	COG0745	RESPONSE REGULATOR receiver
EXW43_06560	COG0501	Belongs to the peptidase M48B family
EXW43_06565	COG0697	spore germination
EXW43_06595	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW43_06600	COG2224	Isocitrate lyase
EXW43_06610	COG1278	Cold shock
EXW43_06630	COG4903	ComK protein
EXW43_06635	COG0398	Pfam SNARE associated Golgi protein
EXW43_06645	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW43_06650	COG1074	ATP-dependent DNA helicase activity
EXW43_06700	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW43_06725	COG0367	asparagine synthase
EXW43_06735	COG0753	catalase activity
EXW43_06740	COG0004	ammonium transporteR
EXW43_06750	COG1666	GTP binding
EXW43_06755	COG2996	Protein conserved in bacteria
EXW43_06760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW43_06770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW43_06785	COG0561	phosphatase activity
EXW43_06805	COG2267	carboxylic ester hydrolase activity
EXW43_06820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW43_06825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW43_06830	COG5504	Zn-dependent protease
EXW43_06845	COG0180	Tryptophanyl-tRNA synthetase
EXW43_06860	COG4166	transmembrane transport
EXW43_06865	COG0601	transmembrane transport
EXW43_06870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW43_06875	COG0444	Belongs to the ABC transporter superfamily
EXW43_06880	COG4608	Belongs to the ABC transporter superfamily
EXW43_06885	COG0534	Mate efflux family protein
EXW43_06890	COG4166	transmembrane transport
EXW43_06910	COG0861	Integral membrane protein TerC family
EXW43_06915	COG4862	establishment of competence for transformation
EXW43_06920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW43_06930	COG1164	Oligoendopeptidase f
EXW43_06940	COG2346	COG2346, Truncated hemoglobins
EXW43_06945	COG4116	CYTH
EXW43_06955	COG2357	RelA SpoT domain protein
EXW43_06965	COG0564	pseudouridine synthase activity
EXW43_06975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW43_06980	COG0772	Belongs to the SEDS family
EXW43_06985	COG1216	Glycosyl transferase, family 2
EXW43_07005	COG0463	Glycosyl transferase, family 2
EXW43_07005	COG0457	Tetratricopeptide repeat
EXW43_07025	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW43_07040	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW43_07085	COG2153	protein acetylation
EXW43_07090	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW43_07095	COG2382	esterase
EXW43_07120	COG5492	domain, Protein
EXW43_07125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW43_07140	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW43_07140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW43_07145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW43_07150	COG0134	indole-3-glycerol-phosphate synthase activity
EXW43_07155	COG0135	phosphoribosylanthranilate isomerase activity
EXW43_07160	COG0133	tryptophan synthase activity
EXW43_07165	COG0159	tryptophan synthase activity
EXW43_07175	COG1620	l-lactate permease
EXW43_07180	COG5634	Uncharacterized conserved protein (DUF2278)
EXW43_07235	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW43_07240	COG0567	Dehydrogenase, E1 component
EXW43_07245	COG1476	TRANSCRIPTIONal
EXW43_07305	COG1686	Belongs to the peptidase S11 family
EXW43_07310	COG0681	Belongs to the peptidase S26 family
EXW43_07345	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_07355	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW43_07360	COG1177	transmembrane transport
EXW43_07365	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW43_07375	COG2409	Drug exporters of the RND superfamily
EXW43_07385	COG0564	pseudouridine synthase activity
EXW43_07395	COG2340	Cysteine-rich secretory protein family
EXW43_07400	COG0247	lactate metabolic process
EXW43_07405	COG0277	FAD linked oxidase domain protein
EXW43_07410	COG3835	regulator
EXW43_07420	COG0745	RESPONSE REGULATOR receiver
EXW43_07425	COG5002	protein histidine kinase activity
EXW43_07430	COG2186	Transcriptional regulator
EXW43_07435	COG0247	lactate metabolic process
EXW43_07440	COG1139	Iron-sulfur cluster binding protein
EXW43_07445	COG1556	Lactate utilization protein
EXW43_07450	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW43_07465	COG2211	Major facilitator Superfamily
EXW43_07480	COG4974	Belongs to the 'phage' integrase family
EXW43_07490	COG2116	formate transmembrane transporter activity
EXW43_07495	COG0861	Integral membrane protein TerC family
EXW43_07500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW43_07510	COG2030	dehydratase
EXW43_07530	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_07535	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW43_07545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW43_07560	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW43_07565	COG3842	ATPase activity
EXW43_07575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW43_07580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW43_07590	COG1349	DNA-binding transcription factor activity
EXW43_07600	COG0235	Class ii aldolase
EXW43_07610	COG2861	carbohydrate metabolic process
EXW43_07620	COG3852	Histidine kinase
EXW43_07625	COG1846	Transcriptional regulator
EXW43_07635	COG2318	DinB family
EXW43_07640	COG5002	protein histidine kinase activity
EXW43_07645	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW43_07650	COG0720	synthase
EXW43_07660	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW43_07665	COG4873	Protein conserved in bacteria
EXW43_07675	COG0456	acetyltransferase
EXW43_07695	COG1780	Probably involved in ribonucleotide reductase function
EXW43_07710	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW43_07715	COG0531	amino acid
EXW43_07720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW43_07735	COG2204	response regulator
EXW43_07740	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_07750	COG1725	Transcriptional regulator
EXW43_07755	COG1131	(ABC) transporter
EXW43_07765	COG1131	(ABC) transporter
EXW43_07770	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW43_07775	COG1266	CAAX protease self-immunity
EXW43_07785	COG1522	sequence-specific DNA binding
EXW43_07795	COG1335	isochorismatase
EXW43_07805	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW43_07810	COG2070	2-Nitropropane dioxygenase
EXW43_07815	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW43_07820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW43_07825	COG1696	Membrane protein involved in D-alanine export
EXW43_07845	COG0716	FMN binding
EXW43_07870	COG0534	Mate efflux family protein
EXW43_07875	COG1968	undecaprenyl-diphosphatase activity
EXW43_07895	COG1846	Transcriptional regulator
EXW43_07905	COG1301	dicarboxylic acid transport
EXW43_07910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW43_07920	COG3874	Sporulation protein YtfJ
EXW43_07945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW43_07950	COG0028	Belongs to the TPP enzyme family
EXW43_07955	COG0440	acetolactate synthase activity
EXW43_07965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW43_07975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW43_07985	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW43_07990	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW43_08000	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW43_08005	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW43_08010	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW43_08015	COG0107	imidazoleglycerol-phosphate synthase activity
EXW43_08025	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW43_08030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW43_08045	COG1183	phosphatidylcholine synthase activity
EXW43_08050	COG1368	sulfuric ester hydrolase activity
EXW43_08060	COG0019	diaminopimelate decarboxylase activity
EXW43_08070	COG0175	sulfate reduction
EXW43_08075	COG2046	Belongs to the sulfate adenylyltransferase family
EXW43_08080	COG0529	Catalyzes the synthesis of activated sulfate
EXW43_08085	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW43_08105	COG1648	precorrin-2 dehydrogenase activity
EXW43_08115	COG0733	neurotransmitter:sodium symporter activity
EXW43_08135	COG1757	Na H antiporter
EXW43_08150	COG4758	membrane
EXW43_08155	COG4585	Histidine kinase
EXW43_08160	COG2197	response regulator
EXW43_08170	COG1114	Component of the transport system for branched-chain amino acids
EXW43_08180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW43_08225	COG0730	response to heat
EXW43_08230	COG0306	phosphate transporter
EXW43_08235	COG1392	Phosphate transport regulator
EXW43_08240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW43_08255	COG3852	Histidine kinase
EXW43_08260	COG1801	Protein of unknown function DUF72
EXW43_08270	COG0582	viral genome integration into host DNA
EXW43_08275	COG5002	protein histidine kinase activity
EXW43_08290	COG0392	lysyltransferase activity
EXW43_08290	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW43_08305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW43_08310	COG1686	Belongs to the peptidase S11 family
EXW43_08315	COG2715	membrane protein required for spore maturation
EXW43_08320	COG0700	Nucleoside recognition
EXW43_08325	COG1187	pseudouridine synthase activity
EXW43_08335	COG1333	cytochrome c biogenesis protein
EXW43_08340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW43_08345	COG0745	RESPONSE REGULATOR receiver
EXW43_08350	COG5002	protein histidine kinase activity
EXW43_08355	COG2096	Adenosyltransferase
EXW43_08360	COG4942	peptidase
EXW43_08370	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW43_08375	COG1141	Ferredoxin
EXW43_08385	COG4955	Helix-turn-helix domain
EXW43_08390	COG0514	ATP-dependent DNA helicase (RecQ)
EXW43_08395	COG1266	CAAX protease self-immunity
EXW43_08405	COG1408	metallophosphoesterase
EXW43_08420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW43_08440	COG0492	ferredoxin-NADP+ reductase activity
EXW43_08445	COG0252	asparaginase activity
EXW43_08450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW43_08460	COG1304	FMN binding
EXW43_08495	COG1160	GTP binding
EXW43_08500	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW43_08520	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW43_08530	COG0302	gtp cyclohydrolase
EXW43_08535	COG0142	geranyltranstransferase activity
EXW43_08540	COG2226	methyltransferase
EXW43_08545	COG0142	geranyltranstransferase activity
EXW43_08560	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW43_08570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW43_08575	COG0457	Tetratricopeptide repeat
EXW43_08580	COG5582	Belongs to the UPF0302 family
EXW43_08595	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW43_08615	COG4347	Protein of unknown function (DUF1405)
EXW43_08630	COG2738	Putative neutral zinc metallopeptidase
EXW43_08640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW43_08650	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW43_08655	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW43_08660	COG1803	Methylglyoxal synthase
EXW43_08665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW43_08670	COG0438	transferase activity, transferring glycosyl groups
EXW43_08675	COG0617	tRNA 3'-terminal CCA addition
EXW43_08685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW43_08690	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW43_08700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW43_08700	COG1199	ATP-dependent helicase activity
EXW43_08720	COG3935	DnaD domain protein
EXW43_08725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW43_08735	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW43_08735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW43_08740	COG3331	DNA recombination
EXW43_08775	COG4474	Belongs to the UPF0398 family
EXW43_08780	COG3599	regulation of cell shape
EXW43_08790	COG0116	Belongs to the methyltransferase superfamily
EXW43_08800	COG1199	ATP-dependent helicase activity
EXW43_08805	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW43_08815	COG0024	Methionine aminopeptidase
EXW43_08825	COG2233	PERMEase
EXW43_08830	COG2311	Membrane
EXW43_08835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW43_08845	COG0456	acetyltransferase
EXW43_08855	COG2897	thiosulfate sulfurtransferase activity
EXW43_08895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW43_08920	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW43_08935	COG1215	transferase activity, transferring glycosyl groups
EXW43_08940	COG0438	transferase activity, transferring glycosyl groups
EXW43_08955	COG0454	-acetyltransferase
EXW43_08975	COG0328	RNA-DNA hybrid ribonuclease activity
EXW43_09010	COG3403	YqcI/YcgG family
EXW43_09015	COG1280	lysine exporter protein (LysE YggA)
EXW43_09030	COG3162	membrane
EXW43_09035	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW43_09040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW43_09050	COG0475	glutathione-regulated potassium exporter activity
EXW43_09055	COG0789	Transcriptional regulator
EXW43_09055	COG4978	Transcriptional regulator
EXW43_09065	COG2323	membrane
EXW43_09070	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW43_09100	COG2814	Major facilitator Superfamily
EXW43_09120	COG1923	regulation of RNA biosynthetic process
EXW43_09145	COG0784	Response regulator, receiver
EXW43_09145	COG0835	chemotaxis
EXW43_09165	COG0697	spore germination
EXW43_09180	COG0861	Integral membrane protein TerC family
EXW43_09190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW43_09205	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW43_09210	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW43_09210	COG1776	CheC inhibitor of MCP methylation
EXW43_09220	COG1338	Plays a role in the flagellum-specific transport system
EXW43_09225	COG1987	bacterial-type flagellum assembly
EXW43_09235	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW43_09240	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW43_09245	COG1419	protein localization to endoplasmic reticulum
EXW43_09250	COG4786	Flagellar basal body rod
EXW43_09285	COG0412	Dienelactone hydrolase
EXW43_09290	COG2329	Antibiotic biosynthesis monooxygenase
EXW43_09305	COG2814	Major facilitator Superfamily
EXW43_09315	COG0583	DNA-binding transcription factor activity
EXW43_09320	COG3842	ATPase activity
EXW43_09370	COG0406	alpha-ribazole phosphatase activity
EXW43_09400	COG0367	asparagine synthase
EXW43_09430	COG1802	Transcriptional regulator
EXW43_09435	COG0697	spore germination
EXW43_09450	COG0438	transferase activity, transferring glycosyl groups
EXW43_09450	COG1216	Glycosyl transferase, family 2
EXW43_09455	COG1757	Na H antiporter
EXW43_09465	COG0277	FAD linked oxidase domain protein
EXW43_09485	COG0534	Mate efflux family protein
EXW43_09490	COG3340	Belongs to the peptidase S51 family
EXW43_09510	COG0785	Cytochrome C biogenesis protein
EXW43_09515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW43_09530	COG3048	D-serine ammonia-lyase activity
EXW43_09535	COG2733	membrane
EXW43_09575	COG1131	(ABC) transporter
EXW43_09590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW43_09625	COG0528	UMP kinase activity
EXW43_09635	COG1027	Aspartate ammonia-lyase
EXW43_09640	COG0281	malic enzyme
EXW43_09645	COG4191	Histidine kinase
EXW43_09650	COG0784	Response regulator, receiver
EXW43_09655	COG1846	Transcriptional regulator
EXW43_09665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW43_09680	COG2502	aspartate--ammonia ligase
EXW43_09735	COG1051	belongs to the nudix hydrolase family
EXW43_09740	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW43_09750	COG2814	Major facilitator Superfamily
EXW43_09780	COG0477	Major facilitator Superfamily
EXW43_09785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW43_09795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW43_09800	COG2223	nitrite transmembrane transporter activity
EXW43_09805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW43_09820	COG2244	polysaccharide biosynthetic process
EXW43_09825	COG0733	neurotransmitter:sodium symporter activity
EXW43_09835	COG5566	PFAM Mor transcription activator
EXW43_09840	COG2323	membrane
EXW43_09855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW43_09865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW43_09870	COG0028	Belongs to the TPP enzyme family
EXW43_09885	COG0129	dihydroxy-acid dehydratase activity
EXW43_09890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW43_09915	COG2814	Major facilitator Superfamily
EXW43_09920	COG3384	dioxygenase
EXW43_09945	COG4166	transmembrane transport
EXW43_09950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW43_09960	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW43_09965	COG1054	Belongs to the UPF0176 family
EXW43_09975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW43_09980	COG0531	amino acid
EXW43_10015	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW43_10030	COG4257	antibiotic catabolic process
EXW43_10035	COG2390	Transcriptional regulator
EXW43_10045	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW43_10050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW43_10055	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW43_10070	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW43_10085	COG0583	DNA-binding transcription factor activity
EXW43_10105	COG0006	proline dipeptidase activity
EXW43_10110	COG2132	Multicopper oxidase
EXW43_10125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW43_10145	COG1114	Component of the transport system for branched-chain amino acids
EXW43_10155	COG2372	response to copper ion
EXW43_10155	COG1276	copper resistance
EXW43_10160	COG4549	nuclear export factor GLE1
EXW43_10170	COG0697	spore germination
EXW43_10175	COG0583	DNA-binding transcription factor activity
EXW43_10180	COG1959	2 iron, 2 sulfur cluster binding
EXW43_10185	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW43_10190	COG0778	Nitroreductase
EXW43_10205	COG0628	permease
EXW43_10220	COG1231	oxidoreductase activity
EXW43_10225	COG0523	cobalamin synthesis protein
EXW43_10235	COG0318	PFAM AMP-dependent synthetase and ligase
EXW43_10240	COG2030	dehydratase
EXW43_10245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW43_10260	COG0411	ABC transporter
EXW43_10280	COG0583	DNA-binding transcription factor activity
EXW43_10290	COG1942	4-Oxalocrotonate Tautomerase
EXW43_10305	COG0346	lactoylglutathione lyase activity
EXW43_10315	COG1271	oxidase subunit
EXW43_10320	COG1294	oxidase, subunit
EXW43_10325	COG4988	ABC transporter
EXW43_10330	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW43_10360	COG1686	Belongs to the peptidase S11 family
EXW43_10375	COG0791	NLP P60 protein
EXW43_10375	COG1388	LysM domain
EXW43_10385	COG1132	(ABC) transporter
EXW43_10390	COG0745	RESPONSE REGULATOR receiver
EXW43_10395	COG5002	protein histidine kinase activity
EXW43_10400	COG0300	oxidoreductase activity
EXW43_10405	COG4122	O-methyltransferase activity
EXW43_10435	COG0460	homoserine dehydrogenase
EXW43_10445	COG0083	homoserine kinase activity
EXW43_10460	COG1316	TRANSCRIPTIONal
EXW43_10485	COG1285	pathogenesis
EXW43_10490	COG1247	-acetyltransferase
EXW43_10510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW43_10520	COG1082	Xylose isomerase domain protein TIM barrel
EXW43_10530	COG2814	Major facilitator Superfamily
EXW43_10535	COG1279	arginine transmembrane transporter activity
EXW43_10540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW43_10550	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW43_10580	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW43_10585	COG0577	efflux transmembrane transporter activity
EXW43_10590	COG2002	toxin-antitoxin pair type II binding
EXW43_10595	COG1404	Belongs to the peptidase S8 family
EXW43_10600	COG0640	Transcriptional regulator
EXW43_10605	COG0667	Aldo Keto reductase
EXW43_10650	COG3949	Membrane
EXW43_10655	COG0783	Belongs to the Dps family
EXW43_10670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW43_10680	COG1231	oxidoreductase activity
EXW43_10685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW43_10690	COG4989	oxidoreductase activity
EXW43_10695	COG0523	cobalamin synthesis protein
EXW43_10700	COG0456	acetyltransferase
EXW43_10705	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW43_10730	COG1136	(ABC) transporter
EXW43_10735	COG0577	efflux transmembrane transporter activity
EXW43_10740	COG0745	RESPONSE REGULATOR receiver
EXW43_10745	COG2205	protein histidine kinase activity
EXW43_10750	COG1902	pentaerythritol trinitrate reductase activity
EXW43_10755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW43_10765	COG4166	transmembrane transport
EXW43_10770	COG0346	lactoylglutathione lyase activity
EXW43_10780	COG0406	alpha-ribazole phosphatase activity
EXW43_10790	COG5337	Spore coat protein CotH
EXW43_10795	COG1051	belongs to the nudix hydrolase family
EXW43_10800	COG0586	Pfam SNARE associated Golgi protein
EXW43_10805	COG2244	polysaccharide biosynthetic process
EXW43_10815	COG0701	Predicted permease
EXW43_10820	COG3689	TIGRFAM TIGR03943 family protein
EXW43_10825	COG1607	acyl-coa hydrolase
EXW43_10835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW43_10855	COG0702	epimerase
EXW43_10860	COG2839	Protein conserved in bacteria
EXW43_10865	COG1253	flavin adenine dinucleotide binding
EXW43_10890	COG1114	Component of the transport system for branched-chain amino acids
EXW43_10895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW43_10915	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW43_10930	COG1876	peptidase activity
EXW43_10945	COG2211	Major facilitator Superfamily
EXW43_10960	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW43_10970	COG0561	phosphatase activity
EXW43_10980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW43_11000	COG1819	glycosyl
EXW43_11005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW43_11010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW43_11035	COG0456	acetyltransferase
EXW43_11195	COG3874	Sporulation protein YtfJ
EXW43_11220	COG2226	methyltransferase
EXW43_11250	COG0604	alcohol dehydrogenase
EXW43_11255	COG1595	DNA-templated transcription, initiation
EXW43_11280	COG0426	domain, Protein
EXW43_11280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW43_11290	COG0386	Belongs to the glutathione peroxidase family
EXW43_11295	COG1305	Transglutaminase-like
EXW43_11300	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW43_11305	COG0714	Associated with various cellular activities
EXW43_11310	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW43_11315	COG1140	nitrate reductase beta subunit
EXW43_11320	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW43_11325	COG2181	nitrate reductase activity
EXW43_11330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW43_11335	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW43_11340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW43_11345	COG0303	'Molybdopterin
EXW43_11350	COG0314	molybdopterin synthase activity
EXW43_11360	COG2223	nitrite transmembrane transporter activity
EXW43_11385	COG1648	precorrin-2 dehydrogenase activity
EXW43_11395	COG1587	Uroporphyrinogen-III synthase
EXW43_11395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW43_11400	COG2146	nitrite reductase [NAD(P)H] activity
EXW43_11405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW43_11410	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW43_11440	COG2359	stage V sporulation protein S
EXW43_11450	COG1418	mRNA catabolic process
EXW43_11455	COG0488	(ABC) transporter
EXW43_11475	COG1413	lyase activity
EXW43_11490	COG2521	methyltransferase
EXW43_11490	COG2136	Putative SAM-dependent methyltransferase
EXW43_11555	COG0017	Asparaginyl-tRNA synthetase
EXW43_11560	COG0733	neurotransmitter:sodium symporter activity
EXW43_11585	COG2610	gluconate transmembrane transporter activity
EXW43_11595	COG1794	racemase activity, acting on amino acids and derivatives
EXW43_11605	COG0456	acetyltransferase
EXW43_11610	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW43_11620	COG1131	(ABC) transporter
EXW43_11625	COG4473	ABC transporter
EXW43_11635	COG0546	phosphoglycolate phosphatase activity
EXW43_11650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW43_11665	COG0768	penicillin binding
EXW43_11675	COG0204	Acyl-transferase
EXW43_11680	COG1272	protein, Hemolysin III
EXW43_11685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW43_11690	COG0805	protein transport
EXW43_11705	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW43_11710	COG1999	signal sequence binding
EXW43_11715	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW43_11720	COG0367	asparagine synthase
EXW43_11735	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW43_11740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW43_11745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW43_11765	COG1335	isochorismatase
EXW43_11775	COG0668	transmembrane transport
EXW43_11780	COG4585	Histidine kinase
EXW43_11780	COG2203	Gaf domain
EXW43_11785	COG2197	response regulator
EXW43_11790	COG1737	Transcriptional regulator
EXW43_11795	COG1064	alcohol dehydrogenase
EXW43_11810	COG1070	Carbohydrate kinase
EXW43_11820	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW43_11840	COG0517	IMP dehydrogenase activity
EXW43_11840	COG1125	glycine betaine transport
EXW43_11845	COG1174	glycine betaine transport
EXW43_11880	COG1253	flavin adenine dinucleotide binding
EXW43_11885	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_11890	COG5506	Protein of unknown function (DUF1694)
EXW43_11905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW43_11910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW43_11915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW43_11920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW43_11925	COG0456	acetyltransferase
EXW43_11930	COG3829	transcription factor binding
EXW43_11935	COG1509	lysine 2,3-aminomutase activity
EXW43_11945	COG4479	Belongs to the UPF0346 family
EXW43_11970	COG0515	serine threonine protein kinase
EXW43_11970	COG3064	Membrane
EXW43_11970	COG4991	sh3 domain protein
EXW43_11980	COG0671	phosphoesterase, PA-phosphatase related
EXW43_11985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW43_11990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW43_12040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW43_12070	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_12090	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW43_12090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW43_12100	COG2814	Major facilitator Superfamily
EXW43_12110	COG0372	Belongs to the citrate synthase family
EXW43_12115	COG2079	MmgE PrpD family protein
EXW43_12120	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW43_12125	COG1960	acyl-CoA dehydrogenase activity
EXW43_12130	COG2084	Dehydrogenase
EXW43_12135	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_12140	COG1280	lysine exporter protein (LysE YggA)
EXW43_12145	COG1024	Enoyl-CoA hydratase
EXW43_12160	COG0420	3'-5' exonuclease activity
EXW43_12180	COG2223	nitrite transmembrane transporter activity
EXW43_12185	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_12190	COG1169	isochorismate synthase
EXW43_12195	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW43_12200	COG3433	isochorismatase activity
EXW43_12200	COG1535	isochorismatase
EXW43_12205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW43_12210	COG3251	PFAM MbtH domain protein
EXW43_12215	COG2814	Major facilitator Superfamily
EXW43_12230	COG0776	regulation of translation
EXW43_12240	COG2318	DinB family
EXW43_12245	COG1115	amino acid carrier protein
EXW43_12260	COG2329	Antibiotic biosynthesis monooxygenase
EXW43_12275	COG1187	pseudouridine synthase activity
EXW43_12280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW43_12285	COG3655	Transcriptional regulator
EXW43_12295	COG1136	(ABC) transporter
EXW43_12305	COG0596	Alpha beta hydrolase
EXW43_12325	COG0028	Belongs to the TPP enzyme family
EXW43_12350	COG1253	flavin adenine dinucleotide binding
EXW43_12380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW43_12400	COG1846	Transcriptional regulator
EXW43_12410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW43_12415	COG1309	transcriptional regulator
EXW43_12445	COG1247	-acetyltransferase
EXW43_12485	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW43_12495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW43_12525	COG0583	DNA-binding transcription factor activity
EXW43_12530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW43_12545	COG0583	DNA-binding transcription factor activity
EXW43_12550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW43_12555	COG2258	MOSC domain
EXW43_12570	COG1132	(ABC) transporter
EXW43_12575	COG1132	(ABC) transporter
EXW43_12615	COG1396	sequence-specific DNA binding
EXW43_12645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW43_12655	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW43_12660	COG1595	DNA-templated transcription, initiation
EXW43_12735	COG1649	PFAM Uncharacterised BCR, COG1649
EXW43_12755	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW43_12760	COG2971	BadF BadG BcrA BcrD
EXW43_12770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW43_12875	COG3645	SOS response
EXW43_12875	COG3646	Phage regulatory protein
EXW43_12930	COG0582	viral genome integration into host DNA
EXW43_12950	COG1136	(ABC) transporter
EXW43_12955	COG3615	Tellurite resistance protein tehB
EXW43_12955	COG0500	methyltransferase
EXW43_12965	COG0693	protein deglycase activity
EXW43_12975	COG0588	phosphoglycerate mutase activity
EXW43_12995	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW43_13000	COG0110	maltose O-acetyltransferase activity
EXW43_13015	COG1136	(ABC) transporter
EXW43_13045	COG1686	Belongs to the peptidase S11 family
EXW43_13070	COG0768	penicillin binding
EXW43_13075	COG0745	RESPONSE REGULATOR receiver
EXW43_13080	COG2205	protein histidine kinase activity
EXW43_13085	COG1136	(ABC) transporter
EXW43_13090	COG0577	efflux transmembrane transporter activity
EXW43_13100	COG1595	DNA-templated transcription, initiation
EXW43_13110	COG0768	penicillin binding
EXW43_13115	COG0768	penicillin binding
EXW43_13135	COG1252	NADH dehydrogenase
EXW43_13140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW43_13140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW43_13165	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW43_13165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW43_13190	COG1136	(ABC) transporter
EXW43_13195	COG0577	efflux transmembrane transporter activity
EXW43_13215	COG1136	(ABC) transporter
EXW43_13315	COG1114	Component of the transport system for branched-chain amino acids
EXW43_13325	COG2239	Acts as a magnesium transporter
EXW43_13360	COG0697	spore germination
EXW43_13385	COG3397	chitin binding
EXW43_13390	COG0823	Involved in the tonB-independent uptake of proteins
EXW43_13400	COG1408	metallophosphoesterase
EXW43_13410	COG1131	(ABC) transporter
EXW43_13420	COG1309	transcriptional regulator
EXW43_13430	COG1960	acyl-CoA dehydrogenase activity
EXW43_13435	COG0439	Biotin carboxylase
EXW43_13440	COG0511	ligase activity, forming carbon-carbon bonds
EXW43_13445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW43_13450	COG1024	Enoyl-CoA hydratase
EXW43_13455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW43_13460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW43_13500	COG0572	uridine kinase
EXW43_13535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW43_13560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW43_13585	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_13590	COG1733	regulation of RNA biosynthetic process
EXW43_13615	COG1309	transcriptional regulator
EXW43_13645	COG0697	spore germination
EXW43_13650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW43_13680	COG2323	membrane
EXW43_13695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW43_13700	COG0697	spore germination
EXW43_13720	COG0201	protein transport
EXW43_13730	COG0737	Belongs to the 5'-nucleotidase family
EXW43_13735	COG3227	Zinc metalloprotease (Elastase)
EXW43_13740	COG1523	belongs to the glycosyl hydrolase 13 family
EXW43_13755	COG0076	glutamate decarboxylase activity
EXW43_13760	COG0657	acetylesterase activity
EXW43_13780	COG0577	efflux transmembrane transporter activity
EXW43_13785	COG1136	(ABC) transporter
EXW43_13800	COG5002	protein histidine kinase activity
EXW43_13805	COG0745	RESPONSE REGULATOR receiver
EXW43_13810	COG1011	Hydrolase
EXW43_13835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW43_13840	COG1183	phosphatidylcholine synthase activity
EXW43_13855	COG1132	(ABC) transporter
EXW43_13890	COG0322	excinuclease ABC activity
EXW43_13915	COG2318	DinB family
EXW43_13930	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW43_13955	COG3878	Protein conserved in bacteria
EXW43_13980	COG1051	belongs to the nudix hydrolase family
EXW43_13985	COG0592	DNA-directed DNA polymerase activity
EXW43_13990	COG2816	NAD+ diphosphatase activity
EXW43_14000	COG2223	nitrite transmembrane transporter activity
EXW43_14005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW43_14015	COG0494	nUDIX hydrolase
EXW43_14035	COG0697	spore germination
EXW43_14040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW43_14055	COG0584	glycerophosphoryl diester phosphodiesterase
EXW43_14070	COG2814	Major facilitator Superfamily
EXW43_14110	COG0768	penicillin binding
EXW43_14115	COG0671	phosphoesterase, PA-phosphatase related
EXW43_14120	COG0604	alcohol dehydrogenase
EXW43_14125	COG5002	protein histidine kinase activity
EXW43_14130	COG0745	RESPONSE REGULATOR receiver
EXW43_14140	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW43_14150	COG2205	protein histidine kinase activity
EXW43_14165	COG1122	ATPase activity
EXW43_14170	COG4720	Psort location CytoplasmicMembrane, score
EXW43_14175	COG1794	racemase activity, acting on amino acids and derivatives
EXW43_14180	COG1819	glycosyl
EXW43_14190	COG0768	penicillin binding
EXW43_14195	COG5002	protein histidine kinase activity
EXW43_14200	COG0561	phosphatase activity
EXW43_14255	COG2124	cytochrome p450
EXW43_14300	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW43_14310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW43_14315	COG0460	homoserine dehydrogenase
EXW43_14335	COG0577	efflux transmembrane transporter activity
EXW43_14340	COG1136	(ABC) transporter
EXW43_14350	COG0488	(ABC) transporter
EXW43_14355	COG0667	Aldo Keto reductase
EXW43_14360	COG0583	DNA-binding transcription factor activity
EXW43_14365	COG2205	protein histidine kinase activity
EXW43_14370	COG0745	RESPONSE REGULATOR receiver
EXW43_14380	COG3773	Cell wall hydrolase
EXW43_14385	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW43_14395	COG3386	PFAM SMP-30 Gluconolaconase
EXW43_14435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW43_14450	COG2959	enzyme of heme biosynthesis
EXW43_14475	COG3483	tryptophan 2,3-dioxygenase activity
EXW43_14480	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW43_14485	COG3844	kynureninase activity
EXW43_14490	COG1309	transcriptional regulator
EXW43_14505	COG3284	Transcriptional regulator
EXW43_14520	COG1349	DNA-binding transcription factor activity
EXW43_14540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW43_14545	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW43_14550	COG0022	dehydrogenase e1 component
EXW43_14555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW43_14575	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_14580	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW43_14580	COG0456	acetyltransferase
EXW43_14610	COG4176	ABC-type proline glycine betaine transport system permease component
EXW43_14615	COG0517	IMP dehydrogenase activity
EXW43_14615	COG4175	Glycine betaine
EXW43_14640	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW43_14645	COG2153	protein acetylation
EXW43_14650	COG3397	chitin binding
EXW43_14660	COG1819	glycosyl
EXW43_14680	COG2205	protein histidine kinase activity
EXW43_14685	COG2226	methyltransferase
EXW43_14690	COG2315	Protein conserved in bacteria
EXW43_14745	COG3973	AAA domain
EXW43_14760	COG0514	ATP-dependent DNA helicase (RecQ)
EXW43_14780	COG4637	Psort location Cytoplasmic, score
EXW43_14790	COG1227	inorganic diphosphatase activity
EXW43_14795	COG3397	chitin binding
EXW43_14800	COG2318	DinB family
EXW43_14820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW43_14825	COG1115	amino acid carrier protein
EXW43_14830	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_14835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW43_14845	COG3938	Belongs to the proline racemase family
EXW43_14850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW43_14890	COG0586	Pfam SNARE associated Golgi protein
EXW43_14905	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW43_14910	COG4166	transmembrane transport
EXW43_14920	COG4948	Mandelate Racemase Muconate Lactonizing
EXW43_14940	COG0667	Aldo Keto reductase
EXW43_14980	COG2936	dipeptidyl-peptidase activity
EXW43_14990	COG0745	RESPONSE REGULATOR receiver
EXW43_15010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW43_15015	COG1164	Oligoendopeptidase f
EXW43_15030	COG1307	EDD domain protein, DegV family
EXW43_15060	COG1335	isochorismatase
EXW43_15075	COG2814	Major facilitator Superfamily
EXW43_15085	COG1664	Polymer-forming cytoskeletal
EXW43_15090	COG0789	Transcriptional regulator
EXW43_15095	COG4533	DNA binding
EXW43_15100	COG2814	Major facilitator Superfamily
EXW43_15100	COG0477	Major facilitator Superfamily
EXW43_15120	COG2261	transglycosylase associated protein
EXW43_15135	COG2226	methyltransferase
EXW43_15170	COG0436	Aminotransferase
EXW43_15175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW43_15200	COG1131	(ABC) transporter
EXW43_15205	COG2188	Transcriptional regulator
EXW43_15245	COG0628	permease
EXW43_15290	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW43_15300	COG0697	spore germination
EXW43_15305	COG2318	DinB family
EXW43_15355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW43_15365	COG2814	Major facilitator Superfamily
EXW43_15370	COG1368	sulfuric ester hydrolase activity
EXW43_15385	COG0488	(ABC) transporter
EXW43_15390	COG2409	Drug exporters of the RND superfamily
EXW43_15390	COG1033	growth of symbiont in host cell
EXW43_15400	COG1309	transcriptional regulator
EXW43_15420	COG0287	Prephenate dehydrogenase
EXW43_15435	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW43_15435	COG1605	Chorismate mutase
EXW43_15475	COG3584	3D domain protein
EXW43_15475	COG1388	LysM domain
EXW43_15485	COG0346	lactoylglutathione lyase activity
EXW43_15495	COG0431	NADPH-dependent FMN reductase
EXW43_15525	COG0579	oxidoreductase
EXW43_15530	COG1879	ABC-type sugar transport system periplasmic component
EXW43_15540	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW43_15545	COG1129	ABC transporter
EXW43_15550	COG2390	Transcriptional regulator
EXW43_15570	COG2226	methyltransferase
EXW43_15595	COG2329	Antibiotic biosynthesis monooxygenase
EXW43_15620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW43_15625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW43_15630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW43_15635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW43_15640	COG3239	Fatty acid desaturase
EXW43_15660	COG3842	ATPase activity
EXW43_15685	COG1175	transmembrane transport
EXW43_15690	COG1349	DNA-binding transcription factor activity
EXW43_15700	COG3655	Transcriptional regulator
EXW43_15715	COG4377	Putative membrane peptidase family (DUF2324)
EXW43_15725	COG3279	Response regulator of the LytR AlgR family
EXW43_15740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW43_15745	COG0346	lactoylglutathione lyase activity
EXW43_15780	COG0714	Associated with various cellular activities
EXW43_15800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW43_15805	COG0753	catalase activity
EXW43_15815	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW43_15835	COG0778	Nitroreductase
EXW43_15840	COG1846	Transcriptional regulator
EXW43_15865	COG3831	ATPase activity
EXW43_15865	COG4884	unkown
EXW43_15885	COG2207	Transcriptional regulator
EXW43_15890	COG0456	acetyltransferase
EXW43_15905	COG0697	spore germination
EXW43_15910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW43_15940	COG0814	amino acid
EXW43_15945	COG0697	spore germination
EXW43_15955	COG0642	Histidine kinase
EXW43_15960	COG0745	RESPONSE REGULATOR receiver
EXW43_15965	COG0596	Alpha beta hydrolase
EXW43_15975	COG0456	acetyltransferase
EXW43_15975	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW43_16000	COG0730	response to heat
EXW43_16015	COG0833	amino acid
EXW43_16025	COG4335	DNA alkylation repair
EXW43_16055	COG0681	Belongs to the peptidase S26 family
EXW43_16060	COG0768	penicillin binding
EXW43_16075	COG3104	oligopeptide transport
EXW43_16080	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW43_16095	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW43_16100	COG1984	allophanate hydrolase subunit 2
EXW43_16105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW43_16110	COG1414	Transcriptional regulator
EXW43_16120	COG3142	Participates in the control of copper homeostasis
EXW43_16130	COG1960	acyl-CoA dehydrogenase activity
EXW43_16155	COG0640	Transcriptional regulator
EXW43_16165	COG3314	Sporulation integral membrane protein YlbJ
EXW43_16185	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW43_16190	COG0577	efflux transmembrane transporter activity
EXW43_16195	COG0577	efflux transmembrane transporter activity
EXW43_16200	COG1136	(ABC) transporter
EXW43_16230	COG3848	Pyruvate phosphate dikinase
EXW43_16230	COG0574	Belongs to the PEP-utilizing enzyme family
EXW43_16240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW43_16265	COG5002	protein histidine kinase activity
EXW43_16270	COG0745	RESPONSE REGULATOR receiver
EXW43_16280	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW43_16310	COG0798	PFAM Bile acid sodium symporter
EXW43_16315	COG0346	lactoylglutathione lyase activity
EXW43_16320	COG0640	Transcriptional regulator
EXW43_16370	COG1522	sequence-specific DNA binding
EXW43_16390	COG0346	lactoylglutathione lyase activity
EXW43_16420	COG0745	RESPONSE REGULATOR receiver
EXW43_16425	COG3850	Histidine kinase
EXW43_16425	COG5002	protein histidine kinase activity
EXW43_16460	COG1073	alpha beta
EXW43_16470	COG0814	amino acid
EXW43_16475	COG1760	l-serine dehydratase
EXW43_16480	COG1760	l-serine dehydratase
EXW43_16490	COG5002	protein histidine kinase activity
EXW43_16495	COG0745	RESPONSE REGULATOR receiver
EXW43_16505	COG5002	protein histidine kinase activity
EXW43_16530	COG4977	sequence-specific DNA binding
EXW43_16570	COG2814	Major facilitator Superfamily
EXW43_16585	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW43_16610	COG1522	sequence-specific DNA binding
EXW43_16620	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW43_16635	COG1136	(ABC) transporter
EXW43_16640	COG0577	efflux transmembrane transporter activity
EXW43_16660	COG5002	protein histidine kinase activity
EXW43_16660	COG3850	Histidine kinase
EXW43_16670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW43_16700	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW43_16720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW43_16765	COG2814	Major facilitator Superfamily
EXW43_16800	COG5444	nuclease activity
EXW43_16840	COG0477	Major facilitator Superfamily
EXW43_16855	COG1846	Transcriptional regulator
EXW43_16860	COG2814	Major facilitator Superfamily
EXW43_16885	COG0640	Transcriptional regulator
EXW43_16915	COG1329	Transcriptional regulator
EXW43_16970	COG5002	protein histidine kinase activity
EXW43_16985	COG1136	(ABC) transporter
EXW43_17000	COG1131	(ABC) transporter
EXW43_17095	COG4187	Peptidase family M20/M25/M40
EXW43_17110	COG2031	fatty acid transporter
EXW43_17120	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW43_17170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW43_17175	COG1288	antiporter activity
EXW43_17180	COG2356	endonuclease I
EXW43_17185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW43_17210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW43_17230	COG1785	Belongs to the alkaline phosphatase family
EXW43_17235	COG0778	Nitroreductase
EXW43_17240	COG1733	regulation of RNA biosynthetic process
EXW43_17255	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_17265	COG1131	(ABC) transporter
EXW43_17295	COG1011	Hydrolase
EXW43_17300	COG2365	Tyrosine phosphatase family
EXW43_17325	COG0346	lactoylglutathione lyase activity
EXW43_17330	COG1940	carbohydrate kinase activity
EXW43_17335	COG0738	Major facilitator superfamily
EXW43_17340	COG0110	maltose O-acetyltransferase activity
EXW43_17355	COG0628	permease
EXW43_17360	COG2261	transglycosylase associated protein
EXW43_17370	COG1720	tRNA m6t6A37 methyltransferase activity
EXW43_17375	COG0500	methyltransferase
EXW43_17385	COG0477	Major facilitator Superfamily
EXW43_17400	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW43_17410	COG1253	flavin adenine dinucleotide binding
EXW43_17415	COG0789	Transcriptional regulator
EXW43_17425	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW43_17450	COG0697	spore germination
EXW43_17460	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW43_17465	COG3813	Protein conserved in bacteria
EXW43_17470	COG2706	6-phosphogluconolactonase activity
EXW43_17475	COG1070	Carbohydrate kinase
EXW43_17485	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW43_17490	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW43_17505	COG0814	amino acid
EXW43_17525	COG1393	Belongs to the ArsC family
EXW43_17535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW43_17550	COG0494	nUDIX hydrolase
EXW43_17565	COG0384	phenazine biosynthesis protein PhzF
EXW43_17575	COG0318	PFAM AMP-dependent synthetase and ligase
EXW43_17580	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW43_17585	COG1733	regulation of RNA biosynthetic process
EXW43_17600	COG1191	sigma factor activity
EXW43_17615	COG1876	peptidase activity
EXW43_17660	COG0741	lytic transglycosylase activity
EXW43_17680	COG2197	response regulator
EXW43_17685	COG4585	Histidine kinase
EXW43_17730	COG5002	protein histidine kinase activity
EXW43_17735	COG0745	RESPONSE REGULATOR receiver
EXW43_17780	COG0814	amino acid
EXW43_17805	COG1151	hydroxylamine reductase activity
EXW43_17830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW43_17840	COG2072	flavoprotein involved in K transport
EXW43_17880	COG0604	alcohol dehydrogenase
EXW43_17885	COG1113	amino acid transport
EXW43_17895	COG2814	Major facilitator Superfamily
EXW43_17905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW43_17910	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_17920	COG0534	Mate efflux family protein
EXW43_17925	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_17930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW43_17945	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW43_17950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW43_17970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW43_17975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW43_17980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW43_17985	COG3739	integral membrane protein
EXW43_18005	COG0583	DNA-binding transcription factor activity
EXW43_18030	COG1193	negative regulation of DNA recombination
EXW43_18050	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW43_18055	COG1164	Oligoendopeptidase f
EXW43_18060	COG2957	Belongs to the agmatine deiminase family
EXW43_18080	COG3781	membrane
EXW43_18095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW43_18130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW43_18135	COG0640	Transcriptional regulator
EXW43_18140	COG0604	alcohol dehydrogenase
EXW43_18145	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW43_18150	COG0457	Tetratricopeptide repeat
EXW43_18165	COG2808	Putative FMN-binding domain
EXW43_18170	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW43_18180	COG0277	FAD linked oxidase domain protein
EXW43_18200	COG1285	pathogenesis
EXW43_18210	COG2514	catechol 2,3-dioxygenase activity
EXW43_18215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW43_18220	COG1126	abc transporter atp-binding protein
EXW43_18225	COG0765	amino acid transport
EXW43_18230	COG2720	vancomycin resistance protein
EXW43_18255	COG1278	Cold shock
EXW43_18265	COG0716	FMN binding
EXW43_18275	COG0494	nUDIX hydrolase
EXW43_18295	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_18305	COG0165	Argininosuccinate lyase
EXW43_18320	COG4145	pantothenate transmembrane transporter activity
EXW43_18330	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_18335	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_18345	COG1657	PFAM Prenyltransferase squalene oxidase
EXW43_18350	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW43_18355	COG2962	Rard protein
EXW43_18360	COG3326	Membrane
EXW43_18365	COG0531	amino acid
EXW43_18400	COG2226	methyltransferase
EXW43_18405	COG4166	transmembrane transport
EXW43_18410	COG4166	transmembrane transport
EXW43_18415	COG4166	transmembrane transport
EXW43_18420	COG1316	TRANSCRIPTIONal
EXW43_18430	COG1595	DNA-templated transcription, initiation
EXW43_18440	COG1131	(ABC) transporter
EXW43_18460	COG0673	inositol 2-dehydrogenase activity
EXW43_18470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW43_18475	COG0187	DNA topoisomerase II activity
EXW43_18480	COG1832	CoA-binding protein
EXW43_18485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW43_18490	COG0745	RESPONSE REGULATOR receiver
EXW43_18500	COG1328	CTP reductase activity
EXW43_18510	COG4841	protein insertion into membrane
EXW43_18515	COG0824	Thioesterase
EXW43_18540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW43_18560	COG1132	(ABC) transporter
EXW43_18565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW43_18595	COG2211	Major facilitator Superfamily
EXW43_18605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW43_18620	COG0183	Belongs to the thiolase family
EXW43_18625	COG0318	PFAM AMP-dependent synthetase and ligase
EXW43_18630	COG1268	BioY protein
EXW43_18635	COG0318	PFAM AMP-dependent synthetase and ligase
EXW43_18640	COG1396	sequence-specific DNA binding
EXW43_18660	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EXW43_18680	COG0830	nickel cation binding
EXW43_18720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW43_18735	COG5002	protein histidine kinase activity
EXW43_18745	COG0400	carboxylic ester hydrolase activity
EXW43_18750	COG0346	lactoylglutathione lyase activity
EXW43_18755	COG0069	glutamate synthase activity
EXW43_18760	COG1902	pentaerythritol trinitrate reductase activity
EXW43_18770	COG1329	Transcriptional regulator
EXW43_18775	COG0010	Belongs to the arginase family
EXW43_18785	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW43_18790	COG2986	histidine ammonia-lyase
EXW43_18800	COG2226	methyltransferase
EXW43_18830	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW43_18835	COG0785	Cytochrome C biogenesis protein
EXW43_18855	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW43_18860	COG1131	(ABC) transporter
EXW43_18870	COG0583	DNA-binding transcription factor activity
EXW43_18880	COG1346	cytolysis
EXW43_18895	COG0730	response to heat
EXW43_18905	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW43_18905	COG3409	Peptidoglycan-binding domain 1 protein
EXW43_18925	COG1132	(ABC) transporter
EXW43_18930	COG1132	(ABC) transporter
EXW43_18935	COG3763	UPF0154 protein
EXW43_18955	COG3639	organic phosphonate transmembrane transporter activity
EXW43_18965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW43_18970	COG0737	Belongs to the 5'-nucleotidase family
EXW43_18980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW43_18985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW43_19000	COG1695	Transcriptional regulator
EXW43_19005	COG0174	glutamine synthetase
EXW43_19010	COG0789	Transcriptional regulator
EXW43_19015	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW43_19020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW43_19025	COG2860	membrane
EXW43_19030	COG0464	growth
EXW43_19050	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW43_19060	COG3584	3D domain protein
EXW43_19060	COG1388	LysM domain
EXW43_19065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW43_19065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW43_19065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW43_19070	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW43_19075	COG1349	DNA-binding transcription factor activity
EXW43_19080	COG1979	alcohol dehydrogenase
EXW43_19085	COG2322	membrane
EXW43_19095	COG1113	amino acid transport
EXW43_19115	COG1408	metallophosphoesterase
EXW43_19120	COG2116	formate transmembrane transporter activity
EXW43_19135	COG2217	Heavy metal translocating P-type atpase
EXW43_19140	COG2608	mercury ion transmembrane transporter activity
EXW43_19145	COG1937	Protein conserved in bacteria
EXW43_19175	COG4566	intracellular signal transduction
EXW43_19180	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW43_19185	COG2819	hydrolase of the alpha beta superfamily
EXW43_19190	COG1120	ATPase activity
EXW43_19195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW43_19200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW43_19205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW43_19210	COG0708	Exodeoxyribonuclease III
EXW43_19215	COG2169	Transcriptional regulator
EXW43_19220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW43_19225	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW43_19230	COG2706	6-phosphogluconolactonase activity
EXW43_19235	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW43_19240	COG2364	Membrane
EXW43_19250	COG0346	lactoylglutathione lyase activity
EXW43_19255	COG3300	MHYT domain
EXW43_19255	COG5001	Diguanylate cyclase
EXW43_19295	COG1346	cytolysis
EXW43_19305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW43_19310	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW43_19310	COG0596	Alpha beta hydrolase
EXW43_19315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW43_19330	COG2188	Transcriptional regulator
EXW43_19335	COG2723	6-phospho-beta-galactosidase activity
EXW43_19340	COG0823	Involved in the tonB-independent uptake of proteins
EXW43_19345	COG3773	Cell wall hydrolase
EXW43_19355	COG1368	sulfuric ester hydrolase activity
EXW43_19360	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW43_19370	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW43_19375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW43_19380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW43_19390	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW43_19395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW43_19400	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW43_19405	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW43_19405	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW43_19415	COG2359	stage V sporulation protein S
EXW43_19420	COG1692	metallophosphoesterase
EXW43_19425	COG1418	mRNA catabolic process
EXW43_19430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW43_19435	COG1058	Belongs to the CinA family
EXW43_19435	COG1546	Belongs to the CinA family
EXW43_19440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW43_19445	COG1426	Protein conserved in bacteria
EXW43_19460	COG0300	oxidoreductase activity
EXW43_19465	COG0612	Peptidase, M16
EXW43_19470	COG0612	Peptidase, M16
EXW43_19475	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW43_19480	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW43_19485	COG3845	ABC transporter
EXW43_19490	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW43_19495	COG2188	Transcriptional regulator
EXW43_19505	COG1674	ftsk spoiiie
EXW43_19515	COG0740	serine-type endopeptidase activity
EXW43_19520	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW43_19530	COG0527	aspartate kinase activity
EXW43_19535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW43_19540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW43_19545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW43_19550	COG1873	PFAM PRC-barrel domain
EXW43_19555	COG0612	Peptidase, M16
EXW43_19560	COG0726	polysaccharide deacetylase
EXW43_19565	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW43_19575	COG0196	riboflavin kinase activity
EXW43_19585	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW43_19590	COG1550	Protein conserved in bacteria
EXW43_19595	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW43_19600	COG1358	cellular component organization or biogenesis
EXW43_19605	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW43_19610	COG0195	Participates in both transcription termination and antitermination
EXW43_19615	COG0779	Required for maturation of 30S ribosomal subunits
EXW43_19625	COG0442	prolyl-tRNA aminoacylation
EXW43_19630	COG0750	zinc metalloprotease
EXW43_19640	COG4589	Belongs to the CDS family
EXW43_19650	COG0233	cytoplasmic translational termination
EXW43_19655	COG0528	UMP kinase activity
EXW43_19660	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW43_19670	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW43_19675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW43_19680	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW43_19685	COG4974	Belongs to the 'phage' integrase family
EXW43_19690	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW43_19695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW43_19700	COG0758	DNA mediated transformation
EXW43_19705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW43_19710	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW43_19715	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW43_19730	COG0335	large ribosomal subunit rRNA binding
EXW43_19735	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW43_19740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW43_19745	COG1837	Belongs to the UPF0109 family
EXW43_19755	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW43_19765	COG0552	protein localization to endoplasmic reticulum
EXW43_19770	COG1196	nuclear chromosome segregation
EXW43_19775	COG0571	ribonuclease III activity
EXW43_19780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW43_19785	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_19790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW43_19795	COG0416	fatty acid biosynthetic process
EXW43_19800	COG2050	protein possibly involved in aromatic compounds catabolism
EXW43_19800	COG1349	DNA-binding transcription factor activity
EXW43_19805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW43_19810	COG1461	Dihydroxyacetone kinase
EXW43_19815	COG1302	Protein conserved in bacteria
EXW43_19830	COG1564	THIamine pyrophosphokinase
EXW43_19835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW43_19845	COG2815	serine threonine protein kinase
EXW43_19845	COG0515	serine threonine protein kinase
EXW43_19850	COG0631	protein serine/threonine phosphatase activity
EXW43_19855	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW43_19860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW43_19860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW43_19865	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW43_19870	COG0242	peptide deformylase activity
EXW43_19875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW43_19880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW43_19885	COG1758	RNA polymerase activity
EXW43_19900	COG1561	YicC-like family, N-terminal region
EXW43_19905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW43_19915	COG0006	proline dipeptidase activity
EXW43_19935	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW43_19960	COG0167	dihydroorotate dehydrogenase activity
EXW43_19965	COG0543	2 iron, 2 sulfur cluster binding
EXW43_19970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW43_19980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW43_19985	COG0540	Belongs to the ATCase OTCase family
EXW43_19995	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW43_20000	COG0564	pseudouridine synthase activity
EXW43_20005	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW43_20015	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW43_20020	COG3599	regulation of cell shape
EXW43_20025	COG2302	S4 RNA-binding domain
EXW43_20030	COG0762	integral membrane protein
EXW43_20035	COG1799	cell septum assembly
EXW43_20040	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW43_20050	COG1873	PFAM PRC-barrel domain
EXW43_20055	COG1191	sigma factor activity
EXW43_20060	COG1191	sigma factor activity
EXW43_20070	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW43_20075	COG0849	cell division
EXW43_20080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW43_20095	COG0772	Belongs to the SEDS family
EXW43_20100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW43_20105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW43_20110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW43_20115	COG0768	penicillin binding
EXW43_20120	COG0768	penicillin binding
EXW43_20130	COG0275	rRNA processing
EXW43_20135	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW43_20140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW43_20145	COG0454	-acetyltransferase
EXW43_20155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW43_20160	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW43_20165	COG1323	Belongs to the UPF0348 family
EXW43_20170	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW43_20175	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW43_20180	COG3314	Sporulation integral membrane protein YlbJ
EXW43_20190	COG0742	ribosomal rna small subunit methyltransferase
EXW43_20200	COG4471	UPF0298 protein
EXW43_20205	COG3679	Belongs to the UPF0342 family
EXW43_20210	COG0406	alpha-ribazole phosphatase activity
EXW43_20225	COG2340	Cysteine-rich secretory protein family
EXW43_20235	COG3336	cytochrome c oxidase
EXW43_20260	COG0109	protoheme IX farnesyltransferase activity
EXW43_20265	COG1612	heme a metabolic process
EXW43_20270	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW43_20280	COG0772	Belongs to the SEDS family
EXW43_20285	COG4838	Belongs to the UPF0358 family
EXW43_20290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW43_20295	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW43_20305	COG4896	Protein conserved in bacteria
EXW43_20320	COG1217	gtp-binding protein TYPA
EXW43_20330	COG0483	inositol monophosphate 1-phosphatase activity
EXW43_20340	COG4493	Belongs to the UPF0637 family
EXW43_20345	COG4476	Belongs to the UPF0223 family
EXW43_20350	COG1982	Orn Lys Arg decarboxylase major
EXW43_20395	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW43_20400	COG0022	dehydrogenase e1 component
EXW43_20405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW43_20420	COG0561	phosphatase activity
EXW43_20430	COG5503	Protein of unknown function (DUF1447)
EXW43_20435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW43_20440	COG0569	domain protein
EXW43_20450	COG1473	amidohydrolase
EXW43_20455	COG2171	N-acyltransferase activity
EXW43_20460	COG0583	DNA-binding transcription factor activity
EXW43_20465	COG0517	IMP dehydrogenase activity
EXW43_20475	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW43_20485	COG4703	Protein of unknown function (DUF1797)
EXW43_20500	COG2200	EAL domain
EXW43_20505	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_20510	COG1408	metallophosphoesterase
EXW43_20555	COG2814	Major facilitator Superfamily
EXW43_20565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW43_20575	COG3209	COG3209 Rhs family protein
EXW43_20585	COG2205	protein histidine kinase activity
EXW43_20595	COG0436	Aminotransferase
EXW43_20600	COG1609	Transcriptional regulator
EXW43_20605	COG3833	ABC-type maltose transport systems, permease component
EXW43_20610	COG1175	transmembrane transport
EXW43_20615	COG2182	Extracellular solute-binding protein
EXW43_20625	COG0366	Alpha amylase catalytic
EXW43_20630	COG3842	ATPase activity
EXW43_20675	COG0183	Belongs to the thiolase family
EXW43_20715	COG1695	Transcriptional regulator
EXW43_20720	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_20730	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW43_20735	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW43_20740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW43_20745	COG0436	Aminotransferase
EXW43_20750	COG1850	ribulose-bisphosphate carboxylase activity
EXW43_20755	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW43_20760	COG0235	Class ii aldolase
EXW43_20765	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW43_20780	COG2084	Dehydrogenase
EXW43_20790	COG2199	diguanylate cyclase activity
EXW43_20795	COG0778	Nitroreductase
EXW43_20820	COG2190	(PTS) system
EXW43_20820	COG1263	PTS System
EXW43_20820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW43_20825	COG3711	transcriptional antiterminator
EXW43_20835	COG2188	Transcriptional regulator
EXW43_20840	COG0363	glucosamine-6-phosphate deaminase activity
EXW43_20845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW43_20855	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW43_20865	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW43_20875	COG1547	Domain of unknown function (DUF309)
EXW43_20885	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW43_20890	COG4086	secreted protein
EXW43_20895	COG0561	phosphatase activity
EXW43_20900	COG0697	spore germination
EXW43_20915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW43_20940	COG0733	neurotransmitter:sodium symporter activity
EXW43_20960	COG1686	Belongs to the peptidase S11 family
EXW43_20965	COG1725	Transcriptional regulator
EXW43_20970	COG1131	(ABC) transporter
EXW43_20995	COG1846	Transcriptional regulator
EXW43_21010	COG0598	Magnesium transport protein CorA
EXW43_21025	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW43_21035	COG4974	Belongs to the 'phage' integrase family
EXW43_21045	COG0735	belongs to the Fur family
EXW43_21050	COG1300	Membrane
EXW43_21070	COG0667	Aldo Keto reductase
EXW43_21075	COG0656	L-ascorbic acid biosynthetic process
EXW43_21080	COG0456	acetyltransferase
EXW43_21080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW43_21090	COG0737	Belongs to the 5'-nucleotidase family
EXW43_21090	COG1525	nuclease
EXW43_21090	COG4085	toxin activity
EXW43_21095	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW43_21105	COG0596	Alpha beta hydrolase
EXW43_21110	COG2056	Na+-H+ antiporter family
EXW43_21115	COG1609	Transcriptional regulator
EXW43_21120	COG0456	acetyltransferase
EXW43_21125	COG1073	alpha beta
EXW43_21140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW43_21140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW43_21145	COG0307	riboflavin synthase, alpha
EXW43_21150	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW43_21150	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW43_21165	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW43_21170	COG4106	trans-aconitate 2-methyltransferase activity
EXW43_21175	COG1073	alpha beta
EXW43_21175	COG2226	methyltransferase
EXW43_21180	COG0156	8-amino-7-oxononanoate synthase activity
EXW43_21190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW43_21200	COG1757	Na H antiporter
EXW43_21205	COG0737	Belongs to the 5'-nucleotidase family
EXW43_21215	COG1522	sequence-specific DNA binding
EXW43_21250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW43_21260	COG0300	oxidoreductase activity
EXW43_21265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW43_21270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW43_21275	COG1760	l-serine dehydratase
EXW43_21280	COG1760	l-serine dehydratase
EXW43_21290	COG1234	tRNA 3'-trailer cleavage
EXW43_21315	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW43_21320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW43_21330	COG1376	ErfK ybiS ycfS ynhG family protein
EXW43_21335	COG4129	membrane
EXW43_21340	COG1126	abc transporter atp-binding protein
EXW43_21345	COG0765	amino acid transport
EXW43_21350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW43_21365	COG2816	NAD+ diphosphatase activity
EXW43_21370	COG2323	membrane
EXW43_21375	COG0772	Belongs to the SEDS family
EXW43_21385	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW43_21390	COG0022	dehydrogenase e1 component
EXW43_21395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW43_21400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW43_21405	COG3426	butyrate kinase activity
EXW43_21415	COG0280	phosphate acetyltransferase
EXW43_21425	COG3829	transcription factor binding
EXW43_21425	COG3290	protein histidine kinase activity
EXW43_21435	COG0584	glycerophosphoryl diester phosphodiesterase
EXW43_21440	COG3093	addiction module antidote protein HigA
EXW43_21450	COG0745	RESPONSE REGULATOR receiver
EXW43_21460	COG0750	zinc metalloprotease
EXW43_21465	COG0497	DNA recombination
EXW43_21470	COG1438	arginine binding
EXW43_21475	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW43_21480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW43_21485	COG0142	geranyltranstransferase activity
EXW43_21490	COG1722	exodeoxyribonuclease VII activity
EXW43_21495	COG1570	exodeoxyribonuclease VII activity
EXW43_21500	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW43_21505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW43_21510	COG1302	Protein conserved in bacteria
EXW43_21515	COG0439	Biotin carboxylase
EXW43_21520	COG0511	ligase activity, forming carbon-carbon bonds
EXW43_21565	COG3854	ATPases associated with a variety of cellular activities
EXW43_21585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW43_21590	COG0006	proline dipeptidase activity
EXW43_21595	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW43_21605	COG3872	metal-dependent enzyme
EXW43_21615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW43_21650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW43_21660	COG1609	Transcriptional regulator
EXW43_21670	COG2076	Multidrug Resistance protein
EXW43_21675	COG2076	Multidrug Resistance protein
EXW43_21720	COG1725	Transcriptional regulator
EXW43_21735	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW43_21740	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW43_21745	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW43_21750	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW43_21780	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW43_21805	COG4970	Tfp pilus assembly protein FimT
EXW43_21815	COG1459	type II secretion system
EXW43_21820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW43_21875	COG1410	methionine synthase
EXW43_21875	COG0646	methionine synthase
EXW43_21880	COG0646	methionine synthase
EXW43_21880	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW43_21885	COG0626	cystathionine gamma-synthase activity
EXW43_21890	COG0626	cystathionine gamma-synthase activity
EXW43_21905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW43_21915	COG1940	carbohydrate kinase activity
EXW43_21920	COG4483	Protein conserved in bacteria
EXW43_21925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW43_21930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW43_21935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW43_21940	COG0704	Plays a role in the regulation of phosphate uptake
EXW43_21950	COG0581	inorganic phosphate transmembrane transporter activity
EXW43_21955	COG0573	inorganic phosphate transmembrane transporter activity
EXW43_21960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW43_21965	COG0768	penicillin binding
EXW43_21970	COG0477	Major facilitator Superfamily
EXW43_21975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW43_21995	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW43_22000	COG0735	belongs to the Fur family
EXW43_22005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW43_22010	COG1121	(ABC) transporter
EXW43_22015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW43_22025	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW43_22040	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW43_22045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW43_22050	COG2384	SAM-dependent methyltransferase
EXW43_22055	COG2010	Cytochrome c
EXW43_22060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW43_22065	COG0358	DNA primase activity
EXW43_22075	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW43_22080	COG0517	IMP dehydrogenase activity
EXW43_22085	COG1381	Involved in DNA repair and RecF pathway recombination
EXW43_22095	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW43_22100	COG0295	cytidine deaminase activity
EXW43_22105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW43_22110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW43_22115	COG1480	7TM receptor with intracellular HD hydrolase
EXW43_22120	COG1702	phosphate starvation-inducible protein PhoH
EXW43_22135	COG1610	YqeY-like protein
EXW43_22140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW43_22145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW43_22150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW43_22160	COG0484	heat shock protein binding
EXW43_22165	COG0443	Heat shock 70 kDa protein
EXW43_22175	COG1420	regulation of RNA biosynthetic process
EXW43_22180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW43_22185	COG1733	regulation of RNA biosynthetic process
EXW43_22190	COG0481	GTPase activity
EXW43_22200	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW43_22205	COG0268	Binds directly to 16S ribosomal RNA
EXW43_22210	COG1466	dna polymerase III delta subunit
EXW43_22220	COG0658	competence protein
EXW43_22220	COG2333	competence protein COMEC
EXW43_22225	COG2131	deaminase
EXW43_22230	COG1555	photosystem II stabilization
EXW43_22230	COG1596	polysaccharide export
EXW43_22235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW43_22240	COG2226	methyltransferase
EXW43_22245	COG0799	negative regulation of ribosome biogenesis
EXW43_22250	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW43_22255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW43_22260	COG1534	Rna-binding protein
EXW43_22265	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW43_22270	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW43_22275	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW43_22285	COG0688	phosphatidylethanolamine metabolic process
EXW43_22295	COG1595	DNA-templated transcription, initiation
EXW43_22300	COG2357	RelA SpoT domain protein
EXW43_22310	COG1785	Belongs to the alkaline phosphatase family
EXW43_22320	COG2267	carboxylic ester hydrolase activity
EXW43_22360	COG3186	Phenylalanine-4-hydroxylase
EXW43_22365	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW43_22370	COG2514	catechol 2,3-dioxygenase activity
EXW43_22375	COG2259	Doxx family
EXW43_22415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW43_22425	COG1454	alcohol dehydrogenase
EXW43_22425	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_22430	COG0626	cystathionine gamma-synthase activity
EXW43_22435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW43_22440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW43_22445	COG2226	methyltransferase
EXW43_22460	COG0768	penicillin binding
EXW43_22465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW43_22470	COG0572	uridine kinase
EXW43_22475	COG0826	peptidase U32
EXW43_22480	COG0826	peptidase U32
EXW43_22485	COG4122	O-methyltransferase activity
EXW43_22490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW43_22500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW43_22505	COG4472	Bacterial protein of unknown function (DUF965)
EXW43_22510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW43_22520	COG0628	permease
EXW43_22540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW43_22550	COG0482	sulfurtransferase activity
EXW43_22555	COG1104	cysteine desulfurase activity
EXW43_22560	COG1959	2 iron, 2 sulfur cluster binding
EXW43_22565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW43_22575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW43_22580	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW43_22590	COG1490	D-aminoacyl-tRNA deacylase activity
EXW43_22595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW43_22600	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW43_22605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW43_22605	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW43_22610	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW43_22615	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW43_22615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW43_22625	COG2244	polysaccharide biosynthetic process
EXW43_22630	COG2323	membrane
EXW43_22640	COG1862	Preprotein translocase
EXW43_22645	COG0343	queuine tRNA-ribosyltransferase activity
EXW43_22650	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW43_22660	COG2255	four-way junction helicase activity
EXW43_22665	COG0632	four-way junction helicase activity
EXW43_22670	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW43_22695	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW43_22700	COG0157	Belongs to the NadC ModD family
EXW43_22705	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW43_22710	COG1104	cysteine desulfurase activity
EXW43_22715	COG1827	regulation of RNA biosynthetic process
EXW43_22720	COG2258	MOSC domain
EXW43_22725	COG0077	Prephenate dehydratase
EXW43_22730	COG0577	efflux transmembrane transporter activity
EXW43_22735	COG0577	efflux transmembrane transporter activity
EXW43_22740	COG1136	(ABC) transporter
EXW43_22745	COG5002	protein histidine kinase activity
EXW43_22750	COG0745	RESPONSE REGULATOR receiver
EXW43_22755	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW43_22760	COG3290	protein histidine kinase activity
EXW43_22770	COG2868	ribosomal protein
EXW43_22780	COG1530	ribonuclease E activity
EXW43_22785	COG1994	Peptidase M50
EXW43_22790	COG0739	heme binding
EXW43_22795	COG2894	cell division
EXW43_22800	COG0850	regulation of cytokinetic process
EXW43_22815	COG1077	Cell shape determining protein MreB Mrl
EXW43_22820	COG2003	Belongs to the UPF0758 family
EXW43_22825	COG0424	maF-like protein
EXW43_22840	COG0285	dihydrofolate synthase activity
EXW43_22855	COG1388	LysM domain
EXW43_22860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW43_22865	COG0113	porphobilinogen synthase activity
EXW43_22870	COG1587	Uroporphyrinogen-III synthase
EXW43_22875	COG0181	hydroxymethylbilane synthase activity
EXW43_22880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW43_22885	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW43_22890	COG1846	Transcriptional regulator
EXW43_22895	COG1764	response to oxidative stress
EXW43_22900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW43_22910	COG0470	DNA polymerase III
EXW43_22910	COG1067	ATP-dependent peptidase activity
EXW43_22920	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW43_22950	COG0622	Phosphoesterase
EXW43_22960	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW43_22965	COG5401	PFAM Sporulation and spore germination
EXW43_22975	COG0477	Major facilitator Superfamily
EXW43_22980	COG2197	response regulator
EXW43_22985	COG2233	PERMEase
EXW43_22990	COG0402	S-adenosylhomocysteine deaminase activity
EXW43_22995	COG1983	PspC domain protein
EXW43_23000	COG1396	sequence-specific DNA binding
EXW43_23005	COG0697	spore germination
EXW43_23015	COG1959	2 iron, 2 sulfur cluster binding
EXW43_23020	COG1668	transmembrane transport
EXW43_23025	COG4152	abc transporter atp-binding protein
EXW43_23030	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW43_23035	COG1360	Flagellar Motor Protein
EXW43_23040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW43_23045	COG1876	peptidase activity
EXW43_23050	COG0824	Thioesterase
EXW43_23055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW43_23060	COG1053	succinate dehydrogenase
EXW43_23065	COG2009	succinate dehydrogenase
EXW43_23070	COG1719	4-vinyl reductase, 4VR
EXW43_23075	COG0322	excinuclease ABC activity
EXW43_23080	COG3118	belongs to the thioredoxin family
EXW43_23085	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW43_23090	COG2086	electron transfer activity
EXW43_23095	COG1024	Enoyl-CoA hydratase
EXW43_23100	COG1309	transcriptional regulator
EXW43_23105	COG0318	PFAM AMP-dependent synthetase and ligase
EXW43_23125	COG2318	DinB family
EXW43_23145	COG1131	(ABC) transporter
EXW43_23150	COG2205	protein histidine kinase activity
EXW43_23155	COG0745	RESPONSE REGULATOR receiver
EXW43_23160	COG4895	conserved protein (DUF2196)
EXW43_23165	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW43_23175	COG4509	Sortase family
EXW43_23180	COG1120	ATPase activity
EXW43_23195	COG5386	Cell surface protein
EXW43_23205	COG5386	Cell surface protein
EXW43_23210	COG1114	Component of the transport system for branched-chain amino acids
EXW43_23220	COG1193	negative regulation of DNA recombination
EXW43_23225	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW43_23225	COG1796	DNA polymerase
EXW43_23230	COG1286	toxin biosynthetic process
EXW43_23235	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW43_23240	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW43_23265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW43_23270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW43_23280	COG1418	mRNA catabolic process
EXW43_23310	COG2814	Major facilitator Superfamily
EXW43_23315	COG1566	PFAM secretion protein HlyD family protein
EXW43_23320	COG1309	transcriptional regulator
EXW43_23325	COG1363	Peptidase, m42
EXW43_23335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW43_23350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW43_23360	COG1484	DNA-dependent DNA replication
EXW43_23365	COG3611	Membrane attachment protein
EXW43_23370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW43_23375	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW43_23380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW43_23385	COG0237	dephospho-CoA kinase activity
EXW43_23390	COG1971	Probably functions as a manganese efflux pump
EXW43_23400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW43_23400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW43_23405	COG5002	protein histidine kinase activity
EXW43_23410	COG0745	RESPONSE REGULATOR receiver
EXW43_23425	COG0039	L-malate dehydrogenase activity
EXW43_23430	COG0538	isocitrate dehydrogenase activity
EXW43_23435	COG0372	Belongs to the citrate synthase family
EXW43_23450	COG0628	permease
EXW43_23455	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW43_23465	COG0205	6-phosphofructokinase activity
EXW43_23475	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW43_23480	COG1725	Transcriptional regulator
EXW43_23485	COG0281	malic enzyme
EXW43_23490	COG0587	DNA-directed DNA polymerase activity
EXW43_23505	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW43_23525	COG4109	DRTGG domain
EXW43_23535	COG0006	proline dipeptidase activity
EXW43_23565	COG0662	Cupin 2, conserved barrel domain protein
EXW43_23575	COG1476	TRANSCRIPTIONal
EXW43_23590	COG1028	Short-chain dehydrogenase reductase Sdr
EXW43_23595	COG0589	response to stress
EXW43_23615	COG0165	Argininosuccinate lyase
EXW43_23635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW43_23655	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW43_23660	COG0827	DNA restriction-modification system
EXW43_23665	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW43_23670	COG3874	Sporulation protein YtfJ
EXW43_23685	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW43_23695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW43_23710	COG1104	cysteine desulfurase activity
EXW43_23715	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW43_23730	COG1309	transcriptional regulator
EXW43_23735	COG1956	GAF domain-containing protein
EXW43_23740	COG0626	cystathionine gamma-synthase activity
EXW43_23745	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW43_23770	COG1595	DNA-templated transcription, initiation
EXW43_23780	COG0110	maltose O-acetyltransferase activity
EXW43_23785	COG0456	acetyltransferase
EXW43_23790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW43_23795	COG0454	-acetyltransferase
EXW43_23800	COG0517	IMP dehydrogenase activity
EXW43_23805	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW43_23810	COG2267	carboxylic ester hydrolase activity
EXW43_23820	COG0745	RESPONSE REGULATOR receiver
EXW43_23825	COG5002	protein histidine kinase activity
EXW43_23830	COG0666	response to abiotic stimulus
EXW43_23840	COG1970	mechanosensitive ion channel activity
EXW43_23860	COG1609	Transcriptional regulator
EXW43_23870	COG1605	Chorismate mutase
EXW43_23870	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW43_23875	COG4851	CamS sex pheromone cAM373 precursor
EXW43_23880	COG3118	belongs to the thioredoxin family
EXW43_23890	COG2309	aminopeptidase activity
EXW43_23920	COG0697	spore germination
EXW43_23925	COG0789	Transcriptional regulator
EXW43_23930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW43_23940	COG1674	ftsk spoiiie
EXW43_23955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW43_23960	COG4848	Belongs to the UPF0354 family
EXW43_23965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW43_23970	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW43_23975	COG1363	Peptidase, m42
EXW43_23985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW43_23990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW43_24000	COG0510	thiamine kinase activity
EXW43_24005	COG1523	belongs to the glycosyl hydrolase 13 family
EXW43_24015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW43_24020	COG1349	DNA-binding transcription factor activity
EXW43_24025	COG1187	pseudouridine synthase activity
EXW43_24030	COG2244	polysaccharide biosynthetic process
EXW43_24035	COG2081	HI0933 family
EXW43_24040	COG2814	Major facilitator Superfamily
EXW43_24050	COG3832	glyoxalase III activity
EXW43_24070	COG1329	Transcriptional regulator
EXW43_24095	COG0314	molybdopterin synthase activity
EXW43_24100	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW43_24105	COG0303	'Molybdopterin
EXW43_24110	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW43_24115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW43_24120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW43_24145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW43_24155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW43_24195	COG0495	leucyl-tRNA aminoacylation
EXW43_24200	COG2814	Major facilitator Superfamily
EXW43_24205	COG0475	glutathione-regulated potassium exporter activity
EXW43_24210	COG0490	domain, Protein
EXW43_24215	COG0582	viral genome integration into host DNA
EXW43_24230	COG1136	(ABC) transporter
EXW43_24245	COG1242	4 iron, 4 sulfur cluster binding
EXW43_24250	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW43_24260	COG1131	(ABC) transporter
EXW43_24270	COG1794	racemase activity, acting on amino acids and derivatives
EXW43_24290	COG2267	carboxylic ester hydrolase activity
EXW43_24295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW43_24300	COG0671	phosphoesterase, PA-phosphatase related
EXW43_24305	COG0438	transferase activity, transferring glycosyl groups
EXW43_24320	COG0746	molybdenum cofactor guanylyltransferase activity
EXW43_24340	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW43_24345	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW43_24385	COG5002	protein histidine kinase activity
EXW43_24390	COG3852	Histidine kinase
EXW43_24395	COG0753	catalase activity
EXW43_24400	COG2267	carboxylic ester hydrolase activity
EXW43_24410	COG1368	sulfuric ester hydrolase activity
EXW43_24420	COG4895	conserved protein (DUF2196)
EXW43_24435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW43_24440	COG1116	anion transmembrane transporter activity
EXW43_24445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW43_24470	COG0494	nUDIX hydrolase
EXW43_24510	COG2076	Multidrug Resistance protein
EXW43_24515	COG2076	Multidrug Resistance protein
EXW43_24520	COG0789	Transcriptional regulator
EXW43_24525	COG1854	S-ribosylhomocysteine lyase activity
EXW43_24535	COG0288	reversible hydration of carbon dioxide
EXW43_24540	COG1271	oxidase subunit
EXW43_24545	COG1294	oxidase, subunit
EXW43_24565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW43_24590	COG1842	Phage shock protein A
EXW43_24615	COG3859	Proton-coupled thiamine transporter YuaJ
EXW43_24620	COG5002	protein histidine kinase activity
EXW43_24625	COG0745	RESPONSE REGULATOR receiver
EXW43_24650	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW43_24655	COG1597	lipid kinase activity
EXW43_24690	COG1136	(ABC) transporter
EXW43_24720	COG5002	protein histidine kinase activity
EXW43_24730	COG0586	Pfam SNARE associated Golgi protein
EXW43_24745	COG0577	efflux transmembrane transporter activity
EXW43_24750	COG1136	(ABC) transporter
EXW43_24755	COG2207	Transcriptional regulator
EXW43_24755	COG3708	Transcriptional regulator
EXW43_24765	COG1131	(ABC) transporter
EXW43_24775	COG5658	integral membrane protein
EXW43_24780	COG0640	Transcriptional regulator
EXW43_24785	COG0745	RESPONSE REGULATOR receiver
EXW43_24790	COG2205	protein histidine kinase activity
EXW43_24795	COG0577	efflux transmembrane transporter activity
EXW43_24800	COG0577	efflux transmembrane transporter activity
EXW43_24805	COG1136	(ABC) transporter
EXW43_24810	COG0577	efflux transmembrane transporter activity
EXW43_24825	COG2188	Transcriptional regulator
EXW43_24845	COG3964	amidohydrolase
EXW43_24865	COG4948	Mandelate Racemase Muconate Lactonizing
EXW43_24870	COG0318	PFAM AMP-dependent synthetase and ligase
EXW43_24875	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW43_24885	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW43_24890	COG1169	isochorismate synthase
EXW43_24895	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW43_24900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW43_24905	COG1278	Cold shock
EXW43_24915	COG0789	Transcriptional regulator
EXW43_24925	COG0058	SHG alpha-glucan phosphorylase activity
EXW43_24935	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW43_24940	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW43_24945	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW43_25105	COG1285	pathogenesis
EXW43_25110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW43_25120	COG0166	Belongs to the GPI family
EXW43_25130	COG2155	Conserved Protein
EXW43_25135	COG1098	S1 RNA binding domain
EXW43_25140	COG0436	Aminotransferase
EXW43_25145	COG1522	sequence-specific DNA binding
EXW43_25150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW43_25160	COG2267	carboxylic ester hydrolase activity
EXW43_25170	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW43_25185	COG5018	Exonuclease
EXW43_25190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW43_25215	COG2050	protein possibly involved in aromatic compounds catabolism
EXW43_25225	COG1268	BioY protein
EXW43_25230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW43_25235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW43_25245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW43_25250	COG3584	3D domain protein
EXW43_25265	COG1252	NADH dehydrogenase
EXW43_25270	COG0492	ferredoxin-NADP+ reductase activity
EXW43_25275	COG3708	Transcriptional regulator
EXW43_25290	COG1683	Conserved Protein
EXW43_25310	COG0316	Belongs to the HesB IscA family
EXW43_25315	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW43_25320	COG4844	belongs to the
EXW43_25325	COG1252	NADH dehydrogenase
EXW43_25335	COG0390	transport system, permease component
EXW43_25340	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW43_25375	COG4837	Protein of unknown function (DUF1462)
EXW43_25380	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW43_25390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW43_25395	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW43_25410	COG0577	efflux transmembrane transporter activity
EXW43_25410	COG1136	(ABC) transporter
EXW43_25415	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW43_25430	COG0647	UMP catabolic process
EXW43_25440	COG2445	Protein of unknown function DUF86
EXW43_25445	COG1494	fructose-1,6-bisphosphatase
EXW43_25465	COG4470	Protein conserved in bacteria
EXW43_25475	COG0789	Transcriptional regulator
EXW43_25480	COG4377	Putative membrane peptidase family (DUF2324)
EXW43_25500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW43_25505	COG0739	heme binding
EXW43_25515	COG3377	Domain of unknown function (DUF1805)
EXW43_25520	COG0737	Belongs to the 5'-nucleotidase family
EXW43_25525	COG1695	Transcriptional regulator
EXW43_25535	COG0719	Fe-S assembly protein
EXW43_25540	COG0822	iron-sulfur transferase activity
EXW43_25545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW43_25550	COG0719	Fe-S assembly protein
EXW43_25555	COG0396	ATPase activity
EXW43_25560	COG1464	Belongs to the NlpA lipoprotein family
EXW43_25565	COG1464	Belongs to the NlpA lipoprotein family
EXW43_25570	COG2011	ABC-type metal ion transport system permease component
EXW43_25575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW43_25585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW43_25590	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW43_25595	COG0509	glycine decarboxylation via glycine cleavage system
EXW43_25600	COG1393	Belongs to the ArsC family
EXW43_25640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW43_25655	COG1960	acyl-CoA dehydrogenase activity
EXW43_25660	COG0183	Belongs to the thiolase family
EXW43_25665	COG1024	Enoyl-CoA hydratase
EXW43_25665	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW43_25675	COG1686	Belongs to the peptidase S11 family
EXW43_25680	COG0506	proline dehydrogenase activity
EXW43_25690	COG0011	TIGRFAM Protein of
EXW43_25695	COG0840	transmembrane signaling receptor activity
EXW43_25710	COG2814	Major facilitator Superfamily
EXW43_25715	COG0531	amino acid
EXW43_25740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW43_25775	COG0586	Pfam SNARE associated Golgi protein
EXW43_25785	COG1376	ErfK ybiS ycfS ynhG family protein
EXW43_25790	COG0745	RESPONSE REGULATOR receiver
EXW43_25795	COG5002	protein histidine kinase activity
EXW43_25805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW43_25815	COG0840	transmembrane signaling receptor activity
EXW43_25820	COG0840	transmembrane signaling receptor activity
EXW43_25825	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW43_25830	COG3227	Zinc metalloprotease (Elastase)
EXW43_25835	COG1741	Belongs to the pirin family
EXW43_25850	COG0586	Pfam SNARE associated Golgi protein
EXW43_25855	COG0475	glutathione-regulated potassium exporter activity
EXW43_25860	COG0490	domain, Protein
EXW43_25865	COG1115	amino acid carrier protein
EXW43_25870	COG0783	Belongs to the Dps family
EXW43_25880	COG2318	DinB family
EXW43_25885	COG1611	Belongs to the LOG family
EXW43_25895	COG1528	Iron-storage protein
EXW43_25900	COG2311	Membrane
EXW43_25905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW43_25910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW43_25915	COG1115	amino acid carrier protein
EXW43_25920	COG1115	amino acid carrier protein
EXW43_25925	COG2910	NAD(P)H-binding
EXW43_25935	COG0656	L-ascorbic acid biosynthetic process
EXW43_25940	COG2814	Major facilitator Superfamily
EXW43_25945	COG1733	regulation of RNA biosynthetic process
EXW43_25955	COG1252	NADH dehydrogenase
EXW43_25975	COG0840	transmembrane signaling receptor activity
EXW43_25975	COG3290	protein histidine kinase activity
EXW43_26010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW43_26025	COG4224	UPF0291 protein
EXW43_26030	COG1335	isochorismatase
EXW43_26035	COG1522	sequence-specific DNA binding
EXW43_26045	COG1522	sequence-specific DNA binding
EXW43_26050	COG0288	reversible hydration of carbon dioxide
EXW43_26055	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW43_26060	COG2233	PERMEase
EXW43_26085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW43_26105	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW43_26115	COG0557	exoribonuclease II activity
EXW43_26120	COG1647	Serine aminopeptidase, S33
EXW43_26125	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW43_26130	COG1346	cytolysis
EXW43_26145	COG0148	phosphopyruvate hydratase activity
EXW43_26155	COG0149	triose-phosphate isomerase activity
EXW43_26160	COG0126	phosphoglycerate kinase activity
EXW43_26165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW43_26180	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW43_26215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW43_26230	COG2323	membrane
EXW43_26240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW43_26245	COG1481	regulation of sporulation
EXW43_26250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW43_26255	COG1660	Displays ATPase and GTPase activities
EXW43_26260	COG1051	belongs to the nudix hydrolase family
EXW43_26270	COG0492	ferredoxin-NADP+ reductase activity
EXW43_26275	COG0457	Tetratricopeptide repeat
EXW43_26280	COG0110	maltose O-acetyltransferase activity
EXW43_26285	COG0546	phosphoglycolate phosphatase activity
EXW43_26290	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW43_26295	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW43_26300	COG1950	PFAM Membrane protein of
EXW43_26305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW43_26325	COG0789	Transcriptional regulator
EXW43_26360	COG0583	DNA-binding transcription factor activity
EXW43_26365	COG0789	Transcriptional regulator
EXW43_26370	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW43_26375	COG0488	(ABC) transporter
EXW43_26385	COG1132	(ABC) transporter
EXW43_26390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW43_26395	COG3409	Peptidoglycan-binding domain 1 protein
EXW43_26395	COG0793	Belongs to the peptidase S41A family
EXW43_26400	COG2177	Part of the ABC transporter FtsEX involved in
EXW43_26405	COG2884	Cell division ATP-binding protein ftsE
EXW43_26440	COG1131	(ABC) transporter
EXW43_26475	COG1278	Cold shock
EXW43_26480	COG1040	competence protein
EXW43_26485	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW43_26490	COG1388	LysM domain
EXW43_26490	COG0791	NLP P60 protein
EXW43_26495	COG1733	regulation of RNA biosynthetic process
EXW43_26500	COG1307	EDD domain protein, DegV family
EXW43_26505	COG1739	Uncharacterized protein family UPF0029
EXW43_26510	COG1316	TRANSCRIPTIONal
EXW43_26515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW43_26520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW43_26525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW43_26535	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW43_26535	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW43_26555	COG1486	melibiose metabolic process
EXW43_26560	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW43_26565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW43_26585	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW43_26595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW43_26600	COG1301	dicarboxylic acid transport
EXW43_26620	COG1511	domain protein
EXW43_26625	COG0583	DNA-binding transcription factor activity
EXW43_26630	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW43_26635	COG1271	oxidase subunit
EXW43_26640	COG1294	oxidase, subunit
EXW43_26645	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW43_26650	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW43_26655	COG1620	l-lactate permease
EXW43_26665	COG2389	metal-binding protein
EXW43_26680	COG1368	sulfuric ester hydrolase activity
EXW43_26690	COG0791	NLP P60 protein
EXW43_26690	COG1388	LysM domain
EXW43_26695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW43_26705	COG1215	transferase activity, transferring glycosyl groups
EXW43_26710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW43_26715	COG1388	LysM domain
EXW43_26715	COG3584	3D domain protein
EXW43_26730	COG4715	Zinc finger, swim domain protein
EXW43_26735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW43_26795	COG0577	efflux transmembrane transporter activity
EXW43_26800	COG1136	(ABC) transporter
EXW43_26825	COG3850	Histidine kinase
EXW43_26825	COG5002	protein histidine kinase activity
EXW43_26830	COG0745	RESPONSE REGULATOR receiver
EXW43_26835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW43_26840	COG1316	TRANSCRIPTIONal
EXW43_26850	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW43_26860	COG1215	transferase activity, transferring glycosyl groups
EXW43_26890	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW43_26895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW43_26900	COG1086	Polysaccharide biosynthesis protein
EXW43_26905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW43_26910	COG4464	protein tyrosine phosphatase activity
EXW43_26915	COG0489	protein tyrosine kinase activity
EXW43_26920	COG3944	biosynthesis protein
EXW43_26930	COG1132	(ABC) transporter
EXW43_26960	COG0367	asparagine synthase
EXW43_26965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW43_26975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW43_26985	COG1216	Glycosyl transferase, family 2
EXW43_27020	COG1215	transferase activity, transferring glycosyl groups
EXW43_27040	COG0463	Glycosyl transferase, family 2
EXW43_27040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW43_27050	COG0438	transferase activity, transferring glycosyl groups
EXW43_27055	COG0438	transferase activity, transferring glycosyl groups
EXW43_27060	COG1086	Polysaccharide biosynthesis protein
EXW43_27065	COG0489	protein tyrosine kinase activity
EXW43_27070	COG3944	biosynthesis protein
EXW43_27075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW43_27080	COG0438	transferase activity, transferring glycosyl groups
EXW43_27085	COG1215	transferase activity, transferring glycosyl groups
EXW43_27085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW43_27095	COG1134	teichoic acid transport
EXW43_27100	COG1682	transport, permease protein
EXW43_27105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW43_27110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW43_27115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EXW43_27125	COG1609	Transcriptional regulator
EXW43_27135	COG0739	heme binding
EXW43_27150	COG3279	Response regulator of the LytR AlgR family
EXW43_27155	COG2385	sporulation resulting in formation of a cellular spore
EXW43_27170	COG4836	Membrane
EXW43_27175	COG1007	ATP synthesis coupled electron transport
EXW43_27180	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW43_27185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW43_27190	COG0713	ATP synthesis coupled electron transport
EXW43_27195	COG0839	Belongs to the complex I subunit 6 family
EXW43_27205	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW43_27210	COG0649	NAD binding
EXW43_27215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW43_27220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW43_27225	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW43_27230	COG5001	Diguanylate cyclase
EXW43_27230	COG3300	MHYT domain
EXW43_27245	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW43_27250	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW43_27255	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW43_27260	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW43_27265	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW43_27270	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW43_27280	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW43_27315	COG0698	ribose 5-phosphate isomerase
EXW43_27325	COG2190	(PTS) system
EXW43_27330	COG2259	Doxx family
EXW43_27335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW43_27345	COG1971	Probably functions as a manganese efflux pump
EXW43_27350	COG0009	L-threonylcarbamoyladenylate synthase
EXW43_27365	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW43_27370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW43_27375	COG1435	thymidine kinase activity
EXW43_27385	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW43_27390	COG1494	fructose-1,6-bisphosphatase
EXW43_27410	COG4821	SIS domain
EXW43_27415	COG0504	CTP synthase activity
EXW43_27420	COG3343	RNA polymerase activity
EXW43_27430	COG1960	acyl-CoA dehydrogenase activity
EXW43_27435	COG1960	acyl-CoA dehydrogenase activity
EXW43_27440	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW43_27445	COG0183	Belongs to the thiolase family
EXW43_27450	COG0247	lactate metabolic process
EXW43_27450	COG2181	nitrate reductase activity
EXW43_27455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW43_27460	COG4294	response to UV
EXW43_27465	COG5001	Diguanylate cyclase
EXW43_27465	COG3300	MHYT domain
EXW43_27490	COG2197	response regulator
EXW43_27495	COG4585	Histidine kinase
EXW43_27500	COG0842	Transport permease protein
EXW43_27505	COG1131	(ABC) transporter
EXW43_27510	COG0024	Methionine aminopeptidase
EXW43_27515	COG2234	aminopeptidase activity
EXW43_27535	COG4506	Protein conserved in bacteria
EXW43_27540	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW43_27555	COG0010	Belongs to the arginase family
EXW43_27560	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW43_27565	COG2814	Major facilitator Superfamily
EXW43_27570	COG0789	Transcriptional regulator
EXW43_27575	COG0584	glycerophosphoryl diester phosphodiesterase
EXW43_27580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW43_27590	COG1994	Peptidase M50
EXW43_27600	COG1078	dGTPase activity
EXW43_27605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW43_27610	COG1120	ATPase activity
EXW43_27615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW43_27620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW43_27625	COG4844	belongs to the
EXW43_27640	COG0280	phosphate acetyltransferase
EXW43_27645	COG3253	May function as heme-dependent peroxidase
EXW43_27655	COG3773	Cell wall hydrolase
EXW43_27665	COG2363	Small membrane protein
EXW43_27680	COG2233	PERMEase
EXW43_27685	COG0561	phosphatase activity
EXW43_27690	COG2814	Major facilitator Superfamily
EXW43_27695	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW43_27700	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW43_27705	COG1131	(ABC) transporter
EXW43_27710	COG2755	lipolytic protein G-D-S-L family
EXW43_27715	COG1609	Transcriptional regulator
EXW43_27725	COG0460	homoserine dehydrogenase
EXW43_27730	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW43_27735	COG2873	o-acetylhomoserine
EXW43_27750	COG2197	response regulator
EXW43_27755	COG4585	Histidine kinase
EXW43_27755	COG2203	Gaf domain
EXW43_27760	COG0351	phosphomethylpyrimidine kinase
EXW43_27765	COG3706	GGDEF domain
EXW43_27770	COG2879	small protein
EXW43_27775	COG1966	Carbon starvation protein
EXW43_27780	COG3279	Response regulator of the LytR AlgR family
EXW43_27785	COG0477	Major facilitator Superfamily
EXW43_27825	COG1607	acyl-coa hydrolase
EXW43_27830	COG1216	Glycosyl transferase, family 2
EXW43_27840	COG1216	Glycosyl transferase, family 2
EXW43_27850	COG4485	Bacterial membrane protein, YfhO
EXW43_27855	COG0463	Glycosyl transferase, family 2
EXW43_27870	COG1309	transcriptional regulator
EXW43_27875	COG0488	(ABC) transporter
EXW43_27880	COG1309	transcriptional regulator
EXW43_27885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW43_27890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW43_27890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW43_27895	COG0628	permease
EXW43_27905	COG1380	Effector of murein hydrolase LrgA
EXW43_27910	COG3279	Response regulator of the LytR AlgR family
EXW43_27915	COG3275	phosphorelay sensor kinase activity
EXW43_27920	COG2814	Major facilitator Superfamily
EXW43_27925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW43_27930	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW43_27940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW43_27965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW43_27970	COG1272	protein, Hemolysin III
EXW43_27995	COG1164	Oligoendopeptidase f
EXW43_28005	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW43_28015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW43_28020	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW43_28025	COG4853	Protein conserved in bacteria
EXW43_28035	COG5002	protein histidine kinase activity
EXW43_28040	COG0745	RESPONSE REGULATOR receiver
EXW43_28070	COG0305	Participates in initiation and elongation during chromosome replication
EXW43_28075	COG0359	binds to the 23S rRNA
EXW43_28080	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW43_28085	COG4241	membrane
EXW43_28095	COG0629	single-stranded DNA binding
EXW43_28100	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW43_28105	COG0012	GTP binding
EXW43_28110	COG4481	Protein conserved in bacteria
EXW43_28115	COG0668	transmembrane transport
EXW43_28125	COG1475	DNA binding
EXW43_28130	COG1192	Involved in chromosome partitioning
EXW43_28135	COG1475	DNA binding
EXW43_28140	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW43_28145	COG0445	tRNA wobble uridine modification
EXW43_28150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW43_28155	COG1847	R3H domain protein
EXW43_28160	COG0706	membrane insertase activity
EXW43_28165	COG0594	ribonuclease P activity
EXW43_28170	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW43_28220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW43_28255	COG0582	viral genome integration into host DNA
EXW43_28285	COG4974	Belongs to the 'phage' integrase family
EXW43_28360	COG4974	Belongs to the 'phage' integrase family
EXW43_28370	COG0768	penicillin binding
EXW43_28400	COG2732	(Barnase) inhibitor
EXW43_28490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW43_28500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW43_28570	COG0582	viral genome integration into host DNA
EXW43_28580	COG0772	Belongs to the SEDS family
EXW43_28590	COG0741	lytic transglycosylase activity
EXW43_28605	COG0577	efflux transmembrane transporter activity
EXW43_28610	COG1136	(ABC) transporter
EXW43_28660	COG1595	DNA-templated transcription, initiation
EXW43_28715	COG2002	toxin-antitoxin pair type II binding
EXW43_28775	COG2732	(Barnase) inhibitor
EXW43_28815	COG0531	amino acid
EXW43_28855	COG2226	methyltransferase
EXW43_28870	COG4555	ABC transporter
EXW43_28890	COG0720	synthase
EXW43_28900	COG0302	gtp cyclohydrolase
EXW43_28960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW43_29070	COG1454	alcohol dehydrogenase
EXW43_29070	COG1012	belongs to the aldehyde dehydrogenase family
EXW43_29095	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW43_29105	COG2707	UPF0756 membrane protein
EXW43_29110	COG0596	Alpha beta hydrolase
EXW43_29115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW43_29140	COG1388	LysM domain
EXW43_29160	COG0494	nUDIX hydrolase
EXW43_29165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW43_29170	COG5566	PFAM Mor transcription activator
EXW43_29260	COG0791	NLP P60 protein
EXW43_29260	COG3883	PFAM NLP P60 protein
EXW43_29380	COG1192	Involved in chromosome partitioning
EXW43_29535	COG3773	Cell wall hydrolase
EXW43_29555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW43_29570	COG1674	ftsk spoiiie
EXW43_29585	COG2002	toxin-antitoxin pair type II binding
EXW43_29610	COG0741	lytic transglycosylase activity
EXW43_29635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW43_29655	COG2002	toxin-antitoxin pair type II binding
EXW43_29695	COG0457	Tetratricopeptide repeat
EXW43_29790	COG3331	DNA recombination
EXW43_29800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW43_29800	COG2755	lipolytic protein G-D-S-L family
EXW43_29855	COG0583	DNA-binding transcription factor activity
EXW43_29860	COG1942	4-Oxalocrotonate Tautomerase
EXW43_29870	COG1073	alpha beta
EXW43_29950	COG0577	efflux transmembrane transporter activity
EXW43_29955	COG1136	(ABC) transporter
EXW43_29960	COG0745	RESPONSE REGULATOR receiver
EXW43_30035	COG2814	Major facilitator Superfamily
EXW43_30060	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW43_30075	COG2002	toxin-antitoxin pair type II binding
EXW43_30105	COG0582	viral genome integration into host DNA
EXW43_30265	COG4974	Belongs to the 'phage' integrase family
EXW43_30350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW43_30405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW43_30420	COG2002	toxin-antitoxin pair type II binding
EXW43_30450	COG2333	competence protein COMEC
EXW43_30450	COG0658	competence protein
EXW43_30505	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW43_30505	COG3409	Peptidoglycan-binding domain 1 protein
EXW43_30580	COG0577	efflux transmembrane transporter activity
EXW43_30585	COG1136	(ABC) transporter
EXW43_30610	COG3227	Zinc metalloprotease (Elastase)
EXW43_30615	COG2373	Large extracellular alpha-helical protein
EXW43_30620	COG3409	Peptidoglycan-binding domain 1 protein
EXW43_30620	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW43_30655	COG2312	Erythromycin esterase
EXW43_30705	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW43_30765	COG5444	nuclease activity
EXW43_30780	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW43_30810	COG0443	Heat shock 70 kDa protein
EXW43_30860	COG1136	(ABC) transporter
EXW43_30860	COG0577	efflux transmembrane transporter activity
EXW43_30885	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW43_31205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW43_31250	COG0582	viral genome integration into host DNA