locus-tag	class	description
EXW55_00005	COG1802	Transcriptional regulator
EXW55_00005	COG4626	Terminase
EXW55_00015	COG0740	serine-type endopeptidase activity
EXW55_00115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW55_00120	COG5002	protein histidine kinase activity
EXW55_00125	COG4807	Protein conserved in bacteria
EXW55_00150	COG1757	Na H antiporter
EXW55_00155	COG1473	amidohydrolase
EXW55_00170	COG0450	alkyl hydroperoxide reductase
EXW55_00180	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW55_00190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW55_00195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW55_00200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW55_00210	COG0492	ferredoxin-NADP+ reductase activity
EXW55_00225	COG0166	Belongs to the GPI family
EXW55_00250	COG5002	protein histidine kinase activity
EXW55_00270	COG3541	Predicted nucleotidyltransferase
EXW55_00275	COG0723	plastoquinol--plastocyanin reductase activity
EXW55_00275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW55_00285	COG0765	amino acid transport
EXW55_00290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW55_00300	COG0840	transmembrane signaling receptor activity
EXW55_00305	COG0277	FAD linked oxidase domain protein
EXW55_00310	COG0366	Alpha amylase catalytic
EXW55_00315	COG2190	(PTS) system
EXW55_00315	COG1263	PTS System
EXW55_00315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW55_00395	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW55_00405	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW55_00420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW55_00425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW55_00430	COG1116	anion transmembrane transporter activity
EXW55_00435	COG0488	(ABC) transporter
EXW55_00470	COG2270	Major facilitator Superfamily
EXW55_00500	COG2310	stress, protein
EXW55_00505	COG2310	stress, protein
EXW55_00510	COG2310	stress, protein
EXW55_00515	COG0861	Integral membrane protein TerC family
EXW55_00525	COG3853	Toxic anion resistance protein (TelA)
EXW55_00535	COG4840	Belongs to the UPF0435 family
EXW55_00550	COG1295	ribonuclease BN
EXW55_00555	COG2217	Heavy metal translocating P-type atpase
EXW55_00560	COG0697	spore germination
EXW55_00580	COG0586	Pfam SNARE associated Golgi protein
EXW55_00595	COG3871	stress protein (general stress protein 26)
EXW55_00600	COG0387	Pfam Sodium calcium exchanger
EXW55_00610	COG0535	radical SAM domain protein
EXW55_00640	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW55_00660	COG3829	transcription factor binding
EXW55_00670	COG0833	amino acid
EXW55_00675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW55_00695	COG2066	Belongs to the glutaminase family
EXW55_00705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW55_00705	COG1263	PTS System
EXW55_00710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW55_00725	COG1216	Glycosyl transferase, family 2
EXW55_00735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW55_00735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW55_00740	COG0463	Glycosyl transferase, family 2
EXW55_00755	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW55_00760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW55_00775	COG1228	amidohydrolase
EXW55_00780	COG1090	epimerase
EXW55_00785	COG2137	regulation of response to DNA damage stimulus
EXW55_00810	COG1988	membrane-bound metal-dependent
EXW55_00815	COG1194	a g-specific adenine glycosylase
EXW55_00835	COG3557	Belongs to the UPF0374 family
EXW55_00840	COG1132	(ABC) transporter
EXW55_00845	COG4129	membrane
EXW55_00850	COG0067	glutamate synthase
EXW55_00850	COG0069	glutamate synthase activity
EXW55_00850	COG0070	glutamate synthase
EXW55_00855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW55_00860	COG4555	ABC transporter
EXW55_00880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW55_00885	COG0735	belongs to the Fur family
EXW55_00990	COG4974	Belongs to the 'phage' integrase family
EXW55_01080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW55_01085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW55_01105	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW55_01115	COG2766	serine protein kinase
EXW55_01120	COG2718	Belongs to the UPF0229 family
EXW55_01135	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW55_01140	COG2268	Band 7 protein
EXW55_01150	COG3290	protein histidine kinase activity
EXW55_01155	COG4565	transcriptional regulatory protein
EXW55_01160	COG2851	Citrate transporter
EXW55_01185	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW55_01190	COG3842	ATPase activity
EXW55_01195	COG1175	transmembrane transport
EXW55_01200	COG0395	ABC-type sugar transport system, permease component
EXW55_01210	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW55_01215	COG0745	RESPONSE REGULATOR receiver
EXW55_01220	COG5002	protein histidine kinase activity
EXW55_01230	COG4990	cell redox homeostasis
EXW55_01240	COG3290	protein histidine kinase activity
EXW55_01245	COG4565	transcriptional regulatory protein
EXW55_01250	COG3493	citrate carrier protein
EXW55_01255	COG0281	malic enzyme
EXW55_01265	COG0697	spore germination
EXW55_01270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW55_01280	COG5002	protein histidine kinase activity
EXW55_01285	COG0745	RESPONSE REGULATOR receiver
EXW55_01290	COG0456	acetyltransferase
EXW55_01295	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW55_01300	COG3383	formate dehydrogenase (NAD+) activity
EXW55_01305	COG2427	Protein of unknown function (DUF1641)
EXW55_01320	COG0531	amino acid
EXW55_01330	COG0640	Transcriptional regulator
EXW55_01335	COG2217	Heavy metal translocating P-type atpase
EXW55_01340	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW55_01350	COG3227	Zinc metalloprotease (Elastase)
EXW55_01370	COG2720	vancomycin resistance protein
EXW55_01375	COG1316	TRANSCRIPTIONal
EXW55_01380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW55_01385	COG0346	lactoylglutathione lyase activity
EXW55_01390	COG1253	flavin adenine dinucleotide binding
EXW55_01395	COG1027	Aspartate ammonia-lyase
EXW55_01400	COG1620	l-lactate permease
EXW55_01405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW55_01425	COG3104	oligopeptide transport
EXW55_01430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW55_01435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW55_01440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW55_01455	COG0156	8-amino-7-oxononanoate synthase activity
EXW55_01460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW55_01470	COG4548	von Willebrand factor, type A
EXW55_01475	COG0714	Associated with various cellular activities
EXW55_01495	COG0531	amino acid
EXW55_01500	COG2188	Transcriptional regulator
EXW55_01505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW55_01505	COG1263	PTS System
EXW55_01510	COG0366	Alpha amylase catalytic
EXW55_01525	COG0697	spore germination
EXW55_01530	COG4585	Histidine kinase
EXW55_01535	COG2197	response regulator
EXW55_01540	COG1404	Belongs to the peptidase S8 family
EXW55_01555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW55_01560	COG1115	amino acid carrier protein
EXW55_01565	COG1126	abc transporter atp-binding protein
EXW55_01570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW55_01575	COG0765	amino acid transport
EXW55_01580	COG0765	amino acid transport
EXW55_01585	COG0833	amino acid
EXW55_01605	COG2378	regulation of single-species biofilm formation
EXW55_01610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW55_01615	COG5002	protein histidine kinase activity
EXW55_01630	COG0659	secondary active sulfate transmembrane transporter activity
EXW55_01655	COG0601	transmembrane transport
EXW55_01660	COG4608	Belongs to the ABC transporter superfamily
EXW55_01670	COG2271	Major facilitator Superfamily
EXW55_01675	COG1846	Transcriptional regulator
EXW55_01680	COG0477	Major facilitator Superfamily
EXW55_01685	COG1609	Transcriptional regulator
EXW55_01690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW55_01695	COG1869	D-ribose catabolic process
EXW55_01705	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW55_01710	COG1879	ABC-type sugar transport system periplasmic component
EXW55_01740	COG1063	alcohol dehydrogenase
EXW55_01755	COG3568	Endonuclease Exonuclease Phosphatase
EXW55_01785	COG0840	transmembrane signaling receptor activity
EXW55_01790	COG3584	3D domain protein
EXW55_01790	COG3583	domain protein
EXW55_01795	COG1476	TRANSCRIPTIONal
EXW55_01815	COG3104	oligopeptide transport
EXW55_01820	COG1114	Component of the transport system for branched-chain amino acids
EXW55_01835	COG1113	amino acid transport
EXW55_01840	COG2252	PERMEase
EXW55_01855	COG2153	protein acetylation
EXW55_01865	COG0569	domain protein
EXW55_01865	COG0475	glutathione-regulated potassium exporter activity
EXW55_01880	COG1845	cytochrome c oxidase, subunit III
EXW55_01885	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW55_01895	COG0833	amino acid
EXW55_01900	COG4990	cell redox homeostasis
EXW55_01915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW55_01920	COG0697	spore germination
EXW55_01925	COG0531	amino acid
EXW55_01935	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW55_01940	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW55_01950	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW55_01955	COG0573	inorganic phosphate transmembrane transporter activity
EXW55_01960	COG0581	inorganic phosphate transmembrane transporter activity
EXW55_01970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW55_02090	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW55_02105	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW55_02105	COG3103	Sh3 type 3 domain protein
EXW55_02105	COG4991	sh3 domain protein
EXW55_02110	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW55_02115	COG1116	anion transmembrane transporter activity
EXW55_02120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW55_02125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW55_02130	COG0352	thiamine-phosphate diphosphorylase activity
EXW55_02135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW55_02140	COG2104	thiamine diphosphate biosynthetic process
EXW55_02150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW55_02155	COG0351	phosphomethylpyrimidine kinase
EXW55_02185	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW55_02190	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW55_02195	COG2205	protein histidine kinase activity
EXW55_02205	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW55_02210	COG1129	ABC transporter
EXW55_02215	COG1879	ABC-type sugar transport system periplasmic component
EXW55_02220	COG2252	PERMEase
EXW55_02225	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_02285	COG0778	Nitroreductase
EXW55_02290	COG2719	SpoVR family
EXW55_02310	COG1937	Protein conserved in bacteria
EXW55_02315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW55_02315	COG0425	Belongs to the sulfur carrier protein TusA family
EXW55_02320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW55_02320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW55_02325	COG0425	Belongs to the sulfur carrier protein TusA family
EXW55_02330	COG0425	Belongs to the sulfur carrier protein TusA family
EXW55_02330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW55_02335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW55_02340	COG2210	Belongs to the sulfur carrier protein TusA family
EXW55_02345	COG0730	response to heat
EXW55_02355	COG1316	TRANSCRIPTIONal
EXW55_02360	COG0604	alcohol dehydrogenase
EXW55_02365	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW55_02375	COG2814	Major facilitator Superfamily
EXW55_02390	COG3711	transcriptional antiterminator
EXW55_02390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW55_02395	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW55_02400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW55_02420	COG1388	LysM domain
EXW55_02420	COG3584	3D domain protein
EXW55_02425	COG0577	efflux transmembrane transporter activity
EXW55_02430	COG1136	(ABC) transporter
EXW55_02440	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW55_02455	COG0577	efflux transmembrane transporter activity
EXW55_02460	COG1114	Component of the transport system for branched-chain amino acids
EXW55_02465	COG3546	catalase activity
EXW55_02490	COG0586	Pfam SNARE associated Golgi protein
EXW55_02520	COG0531	amino acid
EXW55_02525	COG0475	glutathione-regulated potassium exporter activity
EXW55_02535	COG1737	Transcriptional regulator
EXW55_02540	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW55_02545	COG1263	PTS System
EXW55_02545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW55_02555	COG2259	Doxx family
EXW55_02575	COG0697	spore germination
EXW55_02580	COG1522	sequence-specific DNA binding
EXW55_02605	COG2076	Multidrug Resistance protein
EXW55_02610	COG1309	transcriptional regulator
EXW55_02615	COG2814	Major facilitator Superfamily
EXW55_02620	COG1733	regulation of RNA biosynthetic process
EXW55_02640	COG4533	DNA binding
EXW55_02645	COG2211	Major facilitator Superfamily
EXW55_02655	COG0693	protein deglycase activity
EXW55_02665	COG0531	amino acid
EXW55_02670	COG1012	belongs to the aldehyde dehydrogenase family
EXW55_02685	COG1132	(ABC) transporter
EXW55_02690	COG1132	(ABC) transporter
EXW55_02695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW55_02700	COG0765	amino acid transport
EXW55_02705	COG1126	abc transporter atp-binding protein
EXW55_02720	COG0189	ligase activity
EXW55_02730	COG4399	Belongs to the UPF0754 family
EXW55_02735	COG3679	Belongs to the UPF0342 family
EXW55_02750	COG0028	Belongs to the TPP enzyme family
EXW55_02755	COG3527	Alpha-acetolactate decarboxylase
EXW55_02760	COG0463	Glycosyl transferase, family 2
EXW55_02765	COG1216	Glycosyl transferase, family 2
EXW55_02770	COG2094	Belongs to the DNA glycosylase MPG family
EXW55_02775	COG0561	phosphatase activity
EXW55_02785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW55_02790	COG0318	PFAM AMP-dependent synthetase and ligase
EXW55_02795	COG0586	Pfam SNARE associated Golgi protein
EXW55_02805	COG0789	Transcriptional regulator
EXW55_02805	COG4978	Transcriptional regulator
EXW55_02815	COG0659	secondary active sulfate transmembrane transporter activity
EXW55_02830	COG0653	protein targeting
EXW55_02835	COG2244	polysaccharide biosynthetic process
EXW55_02845	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW55_02865	COG1696	Membrane protein involved in D-alanine export
EXW55_02880	COG1024	Enoyl-CoA hydratase
EXW55_02895	COG1363	Peptidase, m42
EXW55_02910	COG2318	DinB family
EXW55_02930	COG0579	oxidoreductase
EXW55_02965	COG0601	transmembrane transport
EXW55_02970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW55_02975	COG0444	Belongs to the ABC transporter superfamily
EXW55_02980	COG4608	Belongs to the ABC transporter superfamily
EXW55_03010	COG0582	viral genome integration into host DNA
EXW55_03145	COG0477	Major facilitator Superfamily
EXW55_03150	COG3290	protein histidine kinase activity
EXW55_03155	COG4565	transcriptional regulatory protein
EXW55_03160	COG3181	Tripartite tricarboxylate transporter family receptor
EXW55_03165	COG0494	nUDIX hydrolase
EXW55_03215	COG0305	Participates in initiation and elongation during chromosome replication
EXW55_03245	COG1309	transcriptional regulator
EXW55_03250	COG1902	pentaerythritol trinitrate reductase activity
EXW55_03255	COG1073	alpha beta
EXW55_03275	COG1842	Phage shock protein A
EXW55_03285	COG0477	Major facilitator Superfamily
EXW55_03375	COG2732	(Barnase) inhibitor
EXW55_03380	COG2814	Major facilitator Superfamily
EXW55_03385	COG0640	Transcriptional regulator
EXW55_03425	COG2376	Dihydroxyacetone kinase
EXW55_03440	COG2376	Dihydroxyacetone kinase
EXW55_03450	COG1959	2 iron, 2 sulfur cluster binding
EXW55_03470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW55_03485	COG2720	vancomycin resistance protein
EXW55_03530	COG3237	CsbD-like
EXW55_03550	COG2172	sigma factor antagonist activity
EXW55_03555	COG1191	sigma factor activity
EXW55_03565	COG2208	phosphoserine phosphatase activity
EXW55_03570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW55_03575	COG0784	Response regulator, receiver
EXW55_03575	COG2205	protein histidine kinase activity
EXW55_03575	COG5002	protein histidine kinase activity
EXW55_03605	COG2807	transmembrane transport
EXW55_03640	COG0420	3'-5' exonuclease activity
EXW55_03645	COG4717	serine-type aminopeptidase activity
EXW55_03650	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW55_03655	COG0346	lactoylglutathione lyase activity
EXW55_03660	COG0346	lactoylglutathione lyase activity
EXW55_03665	COG0457	Tetratricopeptide repeat
EXW55_03675	COG2267	carboxylic ester hydrolase activity
EXW55_03690	COG3620	sequence-specific DNA binding
EXW55_03715	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW55_03720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW55_03725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW55_03730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW55_03745	COG1595	DNA-templated transcription, initiation
EXW55_03765	COG3973	AAA domain
EXW55_03770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW55_03785	COG1846	Transcriptional regulator
EXW55_03795	COG0537	adenosine 5'-monophosphoramidase activity
EXW55_03800	COG1131	(ABC) transporter
EXW55_03805	COG4473	ABC transporter
EXW55_03815	COG0247	lactate metabolic process
EXW55_03820	COG1139	Iron-sulfur cluster binding protein
EXW55_03825	COG1556	Lactate utilization protein
EXW55_03840	COG3402	PFAM membrane-flanked domain
EXW55_03845	COG3428	Bacterial PH domain
EXW55_03885	COG3402	PFAM membrane-flanked domain
EXW55_03890	COG3428	Bacterial PH domain
EXW55_03895	COG2329	Antibiotic biosynthesis monooxygenase
EXW55_03900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW55_03905	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW55_03910	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW55_03915	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW55_03945	COG1309	transcriptional regulator
EXW55_03950	COG1511	domain protein
EXW55_03985	COG2378	regulation of single-species biofilm formation
EXW55_03990	COG1609	Transcriptional regulator
EXW55_04000	COG1234	tRNA 3'-trailer cleavage
EXW55_04005	COG0095	Lipoate-protein ligase
EXW55_04015	COG0318	PFAM AMP-dependent synthetase and ligase
EXW55_04030	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW55_04040	COG4208	sulfate ABC transporter
EXW55_04050	COG3209	COG3209 Rhs family protein
EXW55_04080	COG1408	metallophosphoesterase
EXW55_04085	COG1078	dGTPase activity
EXW55_04100	COG1595	DNA-templated transcription, initiation
EXW55_04110	COG2207	Transcriptional regulator
EXW55_04110	COG3708	Transcriptional regulator
EXW55_04115	COG2205	protein histidine kinase activity
EXW55_04120	COG0745	RESPONSE REGULATOR receiver
EXW55_04140	COG0501	Belongs to the peptidase M48B family
EXW55_04145	COG0697	spore germination
EXW55_04175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW55_04180	COG2224	Isocitrate lyase
EXW55_04190	COG1278	Cold shock
EXW55_04205	COG4903	ComK protein
EXW55_04210	COG0398	Pfam SNARE associated Golgi protein
EXW55_04220	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW55_04225	COG1074	ATP-dependent DNA helicase activity
EXW55_04275	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW55_04300	COG0367	asparagine synthase
EXW55_04310	COG0753	catalase activity
EXW55_04315	COG0004	ammonium transporteR
EXW55_04325	COG1666	GTP binding
EXW55_04330	COG2996	Protein conserved in bacteria
EXW55_04335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW55_04345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW55_04360	COG0561	phosphatase activity
EXW55_04380	COG2267	carboxylic ester hydrolase activity
EXW55_04395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW55_04400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW55_04405	COG5504	Zn-dependent protease
EXW55_04415	COG0180	Tryptophanyl-tRNA synthetase
EXW55_04430	COG4166	transmembrane transport
EXW55_04435	COG0601	transmembrane transport
EXW55_04440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW55_04445	COG0444	Belongs to the ABC transporter superfamily
EXW55_04450	COG4608	Belongs to the ABC transporter superfamily
EXW55_04455	COG0534	Mate efflux family protein
EXW55_04460	COG4166	transmembrane transport
EXW55_04480	COG0861	Integral membrane protein TerC family
EXW55_04485	COG4862	establishment of competence for transformation
EXW55_04490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW55_04500	COG1164	Oligoendopeptidase f
EXW55_04510	COG2346	COG2346, Truncated hemoglobins
EXW55_04515	COG4116	CYTH
EXW55_04525	COG2357	RelA SpoT domain protein
EXW55_04535	COG0564	pseudouridine synthase activity
EXW55_04545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW55_04550	COG0772	Belongs to the SEDS family
EXW55_04555	COG1216	Glycosyl transferase, family 2
EXW55_04575	COG0457	Tetratricopeptide repeat
EXW55_04575	COG0463	Glycosyl transferase, family 2
EXW55_04595	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW55_04610	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW55_04655	COG2153	protein acetylation
EXW55_04660	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW55_04665	COG2382	esterase
EXW55_04690	COG5492	domain, Protein
EXW55_04695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW55_04710	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW55_04710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW55_04715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW55_04720	COG0134	indole-3-glycerol-phosphate synthase activity
EXW55_04725	COG0135	phosphoribosylanthranilate isomerase activity
EXW55_04730	COG0133	tryptophan synthase activity
EXW55_04735	COG0159	tryptophan synthase activity
EXW55_04745	COG1620	l-lactate permease
EXW55_04775	COG1396	sequence-specific DNA binding
EXW55_04805	COG1846	Transcriptional regulator
EXW55_04810	COG1484	DNA-dependent DNA replication
EXW55_04845	COG0582	viral genome integration into host DNA
EXW55_04870	COG5484	DNA packaging
EXW55_04950	COG4824	toxin secretion phage lysis holin
EXW55_05030	COG2226	methyltransferase
EXW55_05050	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW55_05055	COG0567	Dehydrogenase, E1 component
EXW55_05060	COG1476	TRANSCRIPTIONal
EXW55_05090	COG4152	abc transporter atp-binding protein
EXW55_05095	COG1668	transmembrane transport
EXW55_05130	COG1686	Belongs to the peptidase S11 family
EXW55_05135	COG0681	Belongs to the peptidase S26 family
EXW55_05170	COG1012	belongs to the aldehyde dehydrogenase family
EXW55_05180	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW55_05185	COG1177	transmembrane transport
EXW55_05190	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW55_05200	COG2409	Drug exporters of the RND superfamily
EXW55_05210	COG0564	pseudouridine synthase activity
EXW55_05220	COG2340	Cysteine-rich secretory protein family
EXW55_05225	COG0247	lactate metabolic process
EXW55_05230	COG0277	FAD linked oxidase domain protein
EXW55_05235	COG3835	regulator
EXW55_05245	COG0745	RESPONSE REGULATOR receiver
EXW55_05250	COG5002	protein histidine kinase activity
EXW55_05255	COG2186	Transcriptional regulator
EXW55_05260	COG0247	lactate metabolic process
EXW55_05265	COG1139	Iron-sulfur cluster binding protein
EXW55_05270	COG1556	Lactate utilization protein
EXW55_05275	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW55_05285	COG2116	formate transmembrane transporter activity
EXW55_05290	COG0861	Integral membrane protein TerC family
EXW55_05295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW55_05305	COG2030	dehydratase
EXW55_05325	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_05330	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW55_05340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW55_05355	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW55_05360	COG3842	ATPase activity
EXW55_05370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW55_05375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW55_05385	COG1349	DNA-binding transcription factor activity
EXW55_05395	COG0235	Class ii aldolase
EXW55_05405	COG2861	carbohydrate metabolic process
EXW55_05415	COG3852	Histidine kinase
EXW55_05420	COG1846	Transcriptional regulator
EXW55_05430	COG2318	DinB family
EXW55_05435	COG5002	protein histidine kinase activity
EXW55_05440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW55_05445	COG0720	synthase
EXW55_05455	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW55_05460	COG4873	Protein conserved in bacteria
EXW55_05470	COG0456	acetyltransferase
EXW55_05490	COG1780	Probably involved in ribonucleotide reductase function
EXW55_05505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW55_05510	COG0531	amino acid
EXW55_05515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW55_05530	COG2204	response regulator
EXW55_05535	COG1012	belongs to the aldehyde dehydrogenase family
EXW55_05545	COG1725	Transcriptional regulator
EXW55_05550	COG1131	(ABC) transporter
EXW55_05560	COG1131	(ABC) transporter
EXW55_05565	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW55_05570	COG1266	CAAX protease self-immunity
EXW55_05580	COG1522	sequence-specific DNA binding
EXW55_05590	COG1335	isochorismatase
EXW55_05600	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW55_05605	COG2070	2-Nitropropane dioxygenase
EXW55_05610	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW55_05615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW55_05620	COG1696	Membrane protein involved in D-alanine export
EXW55_05625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW55_05640	COG0716	FMN binding
EXW55_05665	COG0534	Mate efflux family protein
EXW55_05685	COG1846	Transcriptional regulator
EXW55_05695	COG1301	dicarboxylic acid transport
EXW55_05700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW55_05710	COG3874	Sporulation protein YtfJ
EXW55_05730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW55_05735	COG0028	Belongs to the TPP enzyme family
EXW55_05740	COG0440	acetolactate synthase activity
EXW55_05750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW55_05760	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW55_05770	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW55_05775	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW55_05785	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW55_05790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW55_05795	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW55_05800	COG0107	imidazoleglycerol-phosphate synthase activity
EXW55_05810	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW55_05815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW55_05830	COG1183	phosphatidylcholine synthase activity
EXW55_05835	COG1368	sulfuric ester hydrolase activity
EXW55_05845	COG0019	diaminopimelate decarboxylase activity
EXW55_05855	COG0175	sulfate reduction
EXW55_05860	COG2046	Belongs to the sulfate adenylyltransferase family
EXW55_05865	COG0529	Catalyzes the synthesis of activated sulfate
EXW55_05870	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW55_05890	COG1648	precorrin-2 dehydrogenase activity
EXW55_05895	COG0733	neurotransmitter:sodium symporter activity
EXW55_05915	COG1757	Na H antiporter
EXW55_05935	COG4758	membrane
EXW55_05940	COG4585	Histidine kinase
EXW55_05945	COG2197	response regulator
EXW55_05955	COG1114	Component of the transport system for branched-chain amino acids
EXW55_05965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW55_06010	COG0730	response to heat
EXW55_06015	COG0306	phosphate transporter
EXW55_06020	COG1392	Phosphate transport regulator
EXW55_06025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW55_06035	COG3852	Histidine kinase
EXW55_06040	COG1801	Protein of unknown function DUF72
EXW55_06050	COG0582	viral genome integration into host DNA
EXW55_06055	COG5002	protein histidine kinase activity
EXW55_06070	COG0392	lysyltransferase activity
EXW55_06070	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW55_06085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW55_06090	COG1686	Belongs to the peptidase S11 family
EXW55_06095	COG2715	membrane protein required for spore maturation
EXW55_06100	COG0700	Nucleoside recognition
EXW55_06105	COG1187	pseudouridine synthase activity
EXW55_06115	COG1333	cytochrome c biogenesis protein
EXW55_06120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW55_06125	COG0745	RESPONSE REGULATOR receiver
EXW55_06130	COG5002	protein histidine kinase activity
EXW55_06135	COG2096	Adenosyltransferase
EXW55_06140	COG4942	peptidase
EXW55_06150	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW55_06155	COG1141	Ferredoxin
EXW55_06165	COG4955	Helix-turn-helix domain
EXW55_06170	COG0514	ATP-dependent DNA helicase (RecQ)
EXW55_06175	COG1266	CAAX protease self-immunity
EXW55_06185	COG1408	metallophosphoesterase
EXW55_06200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW55_06220	COG0492	ferredoxin-NADP+ reductase activity
EXW55_06225	COG0252	asparaginase activity
EXW55_06230	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW55_06240	COG1304	FMN binding
EXW55_06270	COG1160	GTP binding
EXW55_06275	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW55_06295	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW55_06305	COG0302	gtp cyclohydrolase
EXW55_06310	COG0142	geranyltranstransferase activity
EXW55_06315	COG2226	methyltransferase
EXW55_06320	COG0142	geranyltranstransferase activity
EXW55_06335	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW55_06345	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW55_06350	COG0457	Tetratricopeptide repeat
EXW55_06355	COG5582	Belongs to the UPF0302 family
EXW55_06370	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW55_06385	COG4347	Protein of unknown function (DUF1405)
EXW55_06400	COG2738	Putative neutral zinc metallopeptidase
EXW55_06410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW55_06415	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW55_06420	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW55_06425	COG1803	Methylglyoxal synthase
EXW55_06430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW55_06435	COG0438	transferase activity, transferring glycosyl groups
EXW55_06440	COG0617	tRNA 3'-terminal CCA addition
EXW55_06450	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW55_06455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW55_06465	COG1199	ATP-dependent helicase activity
EXW55_06465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW55_06485	COG3935	DnaD domain protein
EXW55_06490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW55_06500	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW55_06500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW55_06505	COG3331	DNA recombination
EXW55_06540	COG4474	Belongs to the UPF0398 family
EXW55_06545	COG3599	regulation of cell shape
EXW55_06555	COG0116	Belongs to the methyltransferase superfamily
EXW55_06565	COG1199	ATP-dependent helicase activity
EXW55_06570	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW55_06580	COG0024	Methionine aminopeptidase
EXW55_06585	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW55_06590	COG2233	PERMEase
EXW55_06595	COG2311	Membrane
EXW55_06600	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW55_06610	COG0456	acetyltransferase
EXW55_06620	COG2897	thiosulfate sulfurtransferase activity
EXW55_06660	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW55_06675	COG0454	-acetyltransferase
EXW55_06695	COG0328	RNA-DNA hybrid ribonuclease activity
EXW55_06730	COG3403	YqcI/YcgG family
EXW55_06735	COG1280	lysine exporter protein (LysE YggA)
EXW55_06750	COG3162	membrane
EXW55_06755	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW55_06760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW55_06770	COG0475	glutathione-regulated potassium exporter activity
EXW55_06775	COG0789	Transcriptional regulator
EXW55_06775	COG4978	Transcriptional regulator
EXW55_06785	COG2323	membrane
EXW55_06790	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW55_06820	COG2814	Major facilitator Superfamily
EXW55_06840	COG1923	regulation of RNA biosynthetic process
EXW55_06850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW55_06855	COG1360	Flagellar Motor Protein
EXW55_06860	COG2201	protein-glutamate methylesterase activity
EXW55_06865	COG0643	Histidine kinase
EXW55_06865	COG2198	Histidine kinase
EXW55_06875	COG1776	CheC inhibitor of MCP methylation
EXW55_06875	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW55_06890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW55_06910	COG1256	bacterial-type flagellum assembly
EXW55_06915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW55_06935	COG1815	bacterial-type flagellum-dependent cell motility
EXW55_06940	COG1558	bacterial-type flagellum-dependent cell motility
EXW55_06950	COG1766	The M ring may be actively involved in energy transduction
EXW55_06955	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW55_06965	COG1157	protein secretion by the type III secretion system
EXW55_06985	COG1749	Flagellar hook protein flgE
EXW55_07000	COG0784	Response regulator, receiver
EXW55_07000	COG0835	chemotaxis
EXW55_07025	COG0861	Integral membrane protein TerC family
EXW55_07035	COG3383	formate dehydrogenase (NAD+) activity
EXW55_07040	COG2427	Protein of unknown function (DUF1641)
EXW55_07045	COG5609	conserved protein (DUF2294)
EXW55_07050	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW55_07060	COG2116	formate transmembrane transporter activity
EXW55_07065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW55_07070	COG0303	'Molybdopterin
EXW55_07075	COG0314	molybdopterin synthase activity
EXW55_07080	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW55_07090	COG0489	protein tyrosine kinase activity
EXW55_07095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW55_07100	COG0741	lytic transglycosylase activity
EXW55_07110	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW55_07115	COG1776	CheC inhibitor of MCP methylation
EXW55_07115	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW55_07125	COG1338	Plays a role in the flagellum-specific transport system
EXW55_07130	COG1987	bacterial-type flagellum assembly
EXW55_07140	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW55_07145	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW55_07150	COG1419	protein localization to endoplasmic reticulum
EXW55_07155	COG4786	Flagellar basal body rod
EXW55_07170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW55_07200	COG0412	Dienelactone hydrolase
EXW55_07205	COG2329	Antibiotic biosynthesis monooxygenase
EXW55_07220	COG2814	Major facilitator Superfamily
EXW55_07230	COG0583	DNA-binding transcription factor activity
EXW55_07235	COG3842	ATPase activity
EXW55_07315	COG0367	asparagine synthase
EXW55_07345	COG1802	Transcriptional regulator
EXW55_07350	COG0697	spore germination
EXW55_07355	COG0438	transferase activity, transferring glycosyl groups
EXW55_07355	COG1216	Glycosyl transferase, family 2
EXW55_07360	COG1757	Na H antiporter
EXW55_07370	COG0277	FAD linked oxidase domain protein
EXW55_07390	COG0534	Mate efflux family protein
EXW55_07395	COG3340	Belongs to the peptidase S51 family
EXW55_07415	COG0785	Cytochrome C biogenesis protein
EXW55_07420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW55_07435	COG3048	D-serine ammonia-lyase activity
EXW55_07440	COG2733	membrane
EXW55_07480	COG1131	(ABC) transporter
EXW55_07500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW55_07505	COG0528	UMP kinase activity
EXW55_07515	COG1027	Aspartate ammonia-lyase
EXW55_07520	COG0281	malic enzyme
EXW55_07525	COG4191	Histidine kinase
EXW55_07530	COG0784	Response regulator, receiver
EXW55_07535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW55_07550	COG2502	aspartate--ammonia ligase
EXW55_07555	COG3620	sequence-specific DNA binding
EXW55_07590	COG1051	belongs to the nudix hydrolase family
EXW55_07595	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW55_07605	COG2814	Major facilitator Superfamily
EXW55_07635	COG0477	Major facilitator Superfamily
EXW55_07650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW55_07655	COG2223	nitrite transmembrane transporter activity
EXW55_07660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW55_07675	COG2244	polysaccharide biosynthetic process
EXW55_07680	COG0733	neurotransmitter:sodium symporter activity
EXW55_07690	COG5566	PFAM Mor transcription activator
EXW55_07695	COG2323	membrane
EXW55_07715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW55_07720	COG2132	Multicopper oxidase
EXW55_07730	COG5002	protein histidine kinase activity
EXW55_07735	COG0745	RESPONSE REGULATOR receiver
EXW55_07745	COG0129	dihydroxy-acid dehydratase activity
EXW55_07750	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW55_07775	COG2814	Major facilitator Superfamily
EXW55_07780	COG3384	dioxygenase
EXW55_07820	COG4166	transmembrane transport
EXW55_07845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW55_07865	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW55_07870	COG1054	Belongs to the UPF0176 family
EXW55_07880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW55_07885	COG0531	amino acid
EXW55_07910	COG2390	Transcriptional regulator
EXW55_07920	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW55_07925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW55_07930	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW55_07945	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW55_07965	COG0583	DNA-binding transcription factor activity
EXW55_07985	COG0006	proline dipeptidase activity
EXW55_07990	COG2132	Multicopper oxidase
EXW55_08005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW55_08015	COG0583	DNA-binding transcription factor activity
EXW55_08035	COG1114	Component of the transport system for branched-chain amino acids
EXW55_08045	COG1834	amidinotransferase
EXW55_08055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW55_08070	COG2372	response to copper ion
EXW55_08070	COG1276	copper resistance
EXW55_08075	COG4549	nuclear export factor GLE1
EXW55_08085	COG0697	spore germination
EXW55_08090	COG0583	DNA-binding transcription factor activity
EXW55_08095	COG1959	2 iron, 2 sulfur cluster binding
EXW55_08100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW55_08105	COG0778	Nitroreductase
EXW55_08120	COG0628	permease
EXW55_08135	COG1231	oxidoreductase activity
EXW55_08140	COG0523	cobalamin synthesis protein
EXW55_08150	COG0318	PFAM AMP-dependent synthetase and ligase
EXW55_08155	COG2030	dehydratase
EXW55_08160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW55_08175	COG0411	ABC transporter
EXW55_08195	COG0583	DNA-binding transcription factor activity
EXW55_08205	COG1942	4-Oxalocrotonate Tautomerase
EXW55_08220	COG0346	lactoylglutathione lyase activity
EXW55_08230	COG1271	oxidase subunit
EXW55_08235	COG1294	oxidase, subunit
EXW55_08240	COG4988	ABC transporter
EXW55_08245	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW55_08275	COG1686	Belongs to the peptidase S11 family
EXW55_08290	COG0791	NLP P60 protein
EXW55_08290	COG1388	LysM domain
EXW55_08300	COG1132	(ABC) transporter
EXW55_08305	COG0745	RESPONSE REGULATOR receiver
EXW55_08310	COG5002	protein histidine kinase activity
EXW55_08315	COG0300	oxidoreductase activity
EXW55_08320	COG4122	O-methyltransferase activity
EXW55_08335	COG5658	integral membrane protein
EXW55_08350	COG0460	homoserine dehydrogenase
EXW55_08360	COG0083	homoserine kinase activity
EXW55_08375	COG1316	TRANSCRIPTIONal
EXW55_08385	COG0745	RESPONSE REGULATOR receiver
EXW55_08390	COG5002	protein histidine kinase activity
EXW55_08405	COG1285	pathogenesis
EXW55_08410	COG1247	-acetyltransferase
EXW55_08430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW55_08440	COG1082	Xylose isomerase domain protein TIM barrel
EXW55_08450	COG2814	Major facilitator Superfamily
EXW55_08455	COG1279	arginine transmembrane transporter activity
EXW55_08460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW55_08470	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW55_08500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW55_08505	COG0577	efflux transmembrane transporter activity
EXW55_08510	COG2002	toxin-antitoxin pair type II binding
EXW55_08515	COG1404	Belongs to the peptidase S8 family
EXW55_08520	COG0640	Transcriptional regulator
EXW55_08525	COG0667	Aldo Keto reductase
EXW55_08570	COG3949	Membrane
EXW55_08575	COG0783	Belongs to the Dps family
EXW55_08590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW55_08600	COG1231	oxidoreductase activity
EXW55_08605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW55_08615	COG2267	carboxylic ester hydrolase activity
EXW55_08620	COG2378	regulation of single-species biofilm formation
EXW55_08640	COG4989	oxidoreductase activity
EXW55_08645	COG0523	cobalamin synthesis protein
EXW55_08650	COG0456	acetyltransferase
EXW55_08655	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW55_08670	COG1902	pentaerythritol trinitrate reductase activity
EXW55_08675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW55_08685	COG4166	transmembrane transport
EXW55_08690	COG0346	lactoylglutathione lyase activity
EXW55_08700	COG0406	alpha-ribazole phosphatase activity
EXW55_08710	COG5337	Spore coat protein CotH
EXW55_08715	COG1051	belongs to the nudix hydrolase family
EXW55_08720	COG0586	Pfam SNARE associated Golgi protein
EXW55_08725	COG2244	polysaccharide biosynthetic process
EXW55_08735	COG0701	Predicted permease
EXW55_08740	COG3689	TIGRFAM TIGR03943 family protein
EXW55_08745	COG1607	acyl-coa hydrolase
EXW55_08755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW55_08770	COG0702	epimerase
EXW55_08775	COG2839	Protein conserved in bacteria
EXW55_08780	COG1253	flavin adenine dinucleotide binding
EXW55_08805	COG1114	Component of the transport system for branched-chain amino acids
EXW55_08810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW55_08830	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW55_08845	COG1876	peptidase activity
EXW55_08850	COG0494	nUDIX hydrolase
EXW55_08860	COG2211	Major facilitator Superfamily
EXW55_08875	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW55_08885	COG0561	phosphatase activity
EXW55_08890	COG1846	Transcriptional regulator
EXW55_08895	COG2814	Major facilitator Superfamily
EXW55_08905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW55_08910	COG4106	trans-aconitate 2-methyltransferase activity
EXW55_08925	COG1819	glycosyl
EXW55_08930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW55_08935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW55_08960	COG0456	acetyltransferase
EXW55_08995	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW55_09065	COG3874	Sporulation protein YtfJ
EXW55_09090	COG2226	methyltransferase
EXW55_09110	COG1082	Xylose isomerase domain protein TIM barrel
EXW55_09115	COG0346	lactoylglutathione lyase activity
EXW55_09125	COG0604	alcohol dehydrogenase
EXW55_09130	COG1595	DNA-templated transcription, initiation
EXW55_09155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW55_09155	COG0426	domain, Protein
EXW55_09165	COG0386	Belongs to the glutathione peroxidase family
EXW55_09170	COG1305	Transglutaminase-like
EXW55_09175	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW55_09180	COG0714	Associated with various cellular activities
EXW55_09185	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW55_09190	COG1140	nitrate reductase beta subunit
EXW55_09195	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW55_09200	COG2181	nitrate reductase activity
EXW55_09205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW55_09210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW55_09215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW55_09220	COG0303	'Molybdopterin
EXW55_09225	COG0314	molybdopterin synthase activity
EXW55_09235	COG2223	nitrite transmembrane transporter activity
EXW55_09255	COG1648	precorrin-2 dehydrogenase activity
EXW55_09265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW55_09265	COG1587	Uroporphyrinogen-III synthase
EXW55_09270	COG2146	nitrite reductase [NAD(P)H] activity
EXW55_09275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW55_09280	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW55_09310	COG2359	stage V sporulation protein S
EXW55_09320	COG1418	mRNA catabolic process
EXW55_09325	COG0488	(ABC) transporter
EXW55_09355	COG1413	lyase activity
EXW55_09370	COG2136	Putative SAM-dependent methyltransferase
EXW55_09370	COG2521	methyltransferase
EXW55_09375	COG0018	arginyl-trna synthetase
EXW55_09390	COG2226	methyltransferase
EXW55_09425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW55_09435	COG0017	Asparaginyl-tRNA synthetase
EXW55_09440	COG0733	neurotransmitter:sodium symporter activity
EXW55_09470	COG2610	gluconate transmembrane transporter activity
EXW55_09480	COG1794	racemase activity, acting on amino acids and derivatives
EXW55_09490	COG0456	acetyltransferase
EXW55_09495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW55_09500	COG1131	(ABC) transporter
EXW55_09505	COG4473	ABC transporter
EXW55_09515	COG0546	phosphoglycolate phosphatase activity
EXW55_09550	COG0768	penicillin binding
EXW55_09565	COG1272	protein, Hemolysin III
EXW55_09570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW55_09575	COG0805	protein transport
EXW55_09585	COG1307	EDD domain protein, DegV family
EXW55_09590	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW55_09595	COG1999	signal sequence binding
EXW55_09600	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW55_09605	COG0367	asparagine synthase
EXW55_09620	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW55_09625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW55_09630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW55_09650	COG1335	isochorismatase
EXW55_09655	COG1051	belongs to the nudix hydrolase family
EXW55_09665	COG0668	transmembrane transport
EXW55_09670	COG2203	Gaf domain
EXW55_09670	COG4585	Histidine kinase
EXW55_09675	COG2197	response regulator
EXW55_09685	COG1737	Transcriptional regulator
EXW55_09690	COG1064	alcohol dehydrogenase
EXW55_09710	COG1070	Carbohydrate kinase
EXW55_09720	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW55_09740	COG1125	glycine betaine transport
EXW55_09740	COG0517	IMP dehydrogenase activity
EXW55_09745	COG1174	glycine betaine transport
EXW55_09780	COG1253	flavin adenine dinucleotide binding
EXW55_09785	COG1012	belongs to the aldehyde dehydrogenase family
EXW55_09790	COG5506	Protein of unknown function (DUF1694)
EXW55_09805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW55_09810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW55_09815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW55_09820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW55_09825	COG0456	acetyltransferase
EXW55_09830	COG3829	transcription factor binding
EXW55_09835	COG1509	lysine 2,3-aminomutase activity
EXW55_09845	COG4479	Belongs to the UPF0346 family
EXW55_09870	COG3064	Membrane
EXW55_09870	COG4991	sh3 domain protein
EXW55_09870	COG0515	serine threonine protein kinase
EXW55_09880	COG0671	phosphoesterase, PA-phosphatase related
EXW55_09885	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW55_09890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW55_09945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW55_09970	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_09990	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW55_09990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW55_10000	COG2814	Major facilitator Superfamily
EXW55_10010	COG0372	Belongs to the citrate synthase family
EXW55_10015	COG2079	MmgE PrpD family protein
EXW55_10020	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW55_10025	COG1960	acyl-CoA dehydrogenase activity
EXW55_10030	COG2084	Dehydrogenase
EXW55_10035	COG1012	belongs to the aldehyde dehydrogenase family
EXW55_10040	COG1280	lysine exporter protein (LysE YggA)
EXW55_10045	COG1024	Enoyl-CoA hydratase
EXW55_10060	COG0420	3'-5' exonuclease activity
EXW55_10085	COG2223	nitrite transmembrane transporter activity
EXW55_10090	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_10095	COG1169	isochorismate synthase
EXW55_10100	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW55_10105	COG1535	isochorismatase
EXW55_10105	COG3433	isochorismatase activity
EXW55_10110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW55_10115	COG3251	PFAM MbtH domain protein
EXW55_10120	COG2814	Major facilitator Superfamily
EXW55_10135	COG0776	regulation of translation
EXW55_10145	COG2318	DinB family
EXW55_10150	COG1115	amino acid carrier protein
EXW55_10165	COG2329	Antibiotic biosynthesis monooxygenase
EXW55_10180	COG1187	pseudouridine synthase activity
EXW55_10185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW55_10190	COG3655	Transcriptional regulator
EXW55_10200	COG1136	(ABC) transporter
EXW55_10210	COG0596	Alpha beta hydrolase
EXW55_10225	COG0028	Belongs to the TPP enzyme family
EXW55_10250	COG1253	flavin adenine dinucleotide binding
EXW55_10300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW55_10320	COG1846	Transcriptional regulator
EXW55_10335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW55_10340	COG1309	transcriptional regulator
EXW55_10370	COG1247	-acetyltransferase
EXW55_10400	COG0596	Alpha beta hydrolase
EXW55_10405	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW55_10415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW55_10445	COG0583	DNA-binding transcription factor activity
EXW55_10450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW55_10500	COG3344	reverse transcriptase
EXW55_10515	COG0583	DNA-binding transcription factor activity
EXW55_10520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW55_10525	COG2258	MOSC domain
EXW55_10540	COG1132	(ABC) transporter
EXW55_10545	COG1132	(ABC) transporter
EXW55_10565	COG1396	sequence-specific DNA binding
EXW55_10605	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW55_10610	COG1595	DNA-templated transcription, initiation
EXW55_10630	COG1649	PFAM Uncharacterised BCR, COG1649
EXW55_10650	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW55_10655	COG2971	BadF BadG BcrA BcrD
EXW55_10720	COG1309	transcriptional regulator
EXW55_10735	COG0577	efflux transmembrane transporter activity
EXW55_10735	COG1136	(ABC) transporter
EXW55_10740	COG3615	Tellurite resistance protein tehB
EXW55_10740	COG0500	methyltransferase
EXW55_10750	COG0693	protein deglycase activity
EXW55_10760	COG0588	phosphoglycerate mutase activity
EXW55_10780	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW55_10795	COG0110	maltose O-acetyltransferase activity
EXW55_10810	COG1136	(ABC) transporter
EXW55_10835	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_10845	COG1686	Belongs to the peptidase S11 family
EXW55_10870	COG0768	penicillin binding
EXW55_10875	COG0745	RESPONSE REGULATOR receiver
EXW55_10880	COG2205	protein histidine kinase activity
EXW55_10885	COG1136	(ABC) transporter
EXW55_10890	COG0577	efflux transmembrane transporter activity
EXW55_10900	COG1595	DNA-templated transcription, initiation
EXW55_10910	COG0768	penicillin binding
EXW55_10915	COG0768	penicillin binding
EXW55_10950	COG1252	NADH dehydrogenase
EXW55_10955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW55_10955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW55_10970	COG0697	spore germination
EXW55_10995	COG3397	chitin binding
EXW55_11000	COG0823	Involved in the tonB-independent uptake of proteins
EXW55_11010	COG1408	metallophosphoesterase
EXW55_11020	COG1131	(ABC) transporter
EXW55_11030	COG1309	transcriptional regulator
EXW55_11040	COG1960	acyl-CoA dehydrogenase activity
EXW55_11045	COG0439	Biotin carboxylase
EXW55_11050	COG0511	ligase activity, forming carbon-carbon bonds
EXW55_11055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW55_11060	COG1024	Enoyl-CoA hydratase
EXW55_11065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW55_11070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW55_11105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW55_11110	COG0572	uridine kinase
EXW55_11115	COG2318	DinB family
EXW55_11145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW55_11170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW55_11195	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_11200	COG1733	regulation of RNA biosynthetic process
EXW55_11220	COG1942	4-Oxalocrotonate Tautomerase
EXW55_11225	COG0583	DNA-binding transcription factor activity
EXW55_11235	COG1309	transcriptional regulator
EXW55_11265	COG0697	spore germination
EXW55_11270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW55_11300	COG2323	membrane
EXW55_11305	COG2132	Multicopper oxidase
EXW55_11320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW55_11325	COG0697	spore germination
EXW55_11330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW55_11335	COG0201	protein transport
EXW55_11345	COG0737	Belongs to the 5'-nucleotidase family
EXW55_11350	COG3227	Zinc metalloprotease (Elastase)
EXW55_11355	COG1523	belongs to the glycosyl hydrolase 13 family
EXW55_11370	COG0076	glutamate decarboxylase activity
EXW55_11375	COG0657	acetylesterase activity
EXW55_11380	COG1073	alpha beta
EXW55_11390	COG0577	efflux transmembrane transporter activity
EXW55_11395	COG1136	(ABC) transporter
EXW55_11425	COG5002	protein histidine kinase activity
EXW55_11430	COG0745	RESPONSE REGULATOR receiver
EXW55_11435	COG1011	Hydrolase
EXW55_11460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW55_11465	COG1183	phosphatidylcholine synthase activity
EXW55_11480	COG1132	(ABC) transporter
EXW55_11485	COG3961	Belongs to the TPP enzyme family
EXW55_11505	COG0322	excinuclease ABC activity
EXW55_11530	COG2318	DinB family
EXW55_11545	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW55_11570	COG3878	Protein conserved in bacteria
EXW55_11595	COG1051	belongs to the nudix hydrolase family
EXW55_11600	COG0592	DNA-directed DNA polymerase activity
EXW55_11605	COG2816	NAD+ diphosphatase activity
EXW55_11615	COG2223	nitrite transmembrane transporter activity
EXW55_11650	COG0697	spore germination
EXW55_11655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW55_11670	COG0584	glycerophosphoryl diester phosphodiesterase
EXW55_11695	COG2814	Major facilitator Superfamily
EXW55_11710	COG2375	cellular response to nickel ion
EXW55_11710	COG1132	(ABC) transporter
EXW55_11715	COG1132	(ABC) transporter
EXW55_11750	COG0768	penicillin binding
EXW55_11755	COG0671	phosphoesterase, PA-phosphatase related
EXW55_11760	COG0604	alcohol dehydrogenase
EXW55_11765	COG5002	protein histidine kinase activity
EXW55_11770	COG0745	RESPONSE REGULATOR receiver
EXW55_11780	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW55_11790	COG2205	protein histidine kinase activity
EXW55_11805	COG1122	ATPase activity
EXW55_11810	COG4720	Psort location CytoplasmicMembrane, score
EXW55_11815	COG1794	racemase activity, acting on amino acids and derivatives
EXW55_11820	COG1819	glycosyl
EXW55_11830	COG0768	penicillin binding
EXW55_11835	COG5002	protein histidine kinase activity
EXW55_11840	COG0561	phosphatase activity
EXW55_11890	COG2124	cytochrome p450
EXW55_11940	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW55_11950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW55_11955	COG0460	homoserine dehydrogenase
EXW55_11975	COG0577	efflux transmembrane transporter activity
EXW55_11980	COG1136	(ABC) transporter
EXW55_11995	COG0488	(ABC) transporter
EXW55_12000	COG0667	Aldo Keto reductase
EXW55_12005	COG0583	DNA-binding transcription factor activity
EXW55_12015	COG2205	protein histidine kinase activity
EXW55_12020	COG0745	RESPONSE REGULATOR receiver
EXW55_12035	COG3773	Cell wall hydrolase
EXW55_12040	COG0604	alcohol dehydrogenase
EXW55_12085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW55_12100	COG2959	enzyme of heme biosynthesis
EXW55_12130	COG3483	tryptophan 2,3-dioxygenase activity
EXW55_12135	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW55_12140	COG3844	kynureninase activity
EXW55_12145	COG1309	transcriptional regulator
EXW55_12160	COG3284	Transcriptional regulator
EXW55_12175	COG1349	DNA-binding transcription factor activity
EXW55_12195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW55_12200	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW55_12205	COG0022	dehydrogenase e1 component
EXW55_12210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW55_12230	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_12235	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW55_12235	COG0456	acetyltransferase
EXW55_12270	COG4176	ABC-type proline glycine betaine transport system permease component
EXW55_12275	COG0517	IMP dehydrogenase activity
EXW55_12275	COG4175	Glycine betaine
EXW55_12300	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW55_12305	COG2153	protein acetylation
EXW55_12310	COG3397	chitin binding
EXW55_12320	COG1819	glycosyl
EXW55_12335	COG2205	protein histidine kinase activity
EXW55_12340	COG2315	Protein conserved in bacteria
EXW55_12395	COG3973	AAA domain
EXW55_12410	COG2105	PFAM AIG2 family protein
EXW55_12415	COG0514	ATP-dependent DNA helicase (RecQ)
EXW55_12435	COG4637	Psort location Cytoplasmic, score
EXW55_12450	COG1227	inorganic diphosphatase activity
EXW55_12455	COG3397	chitin binding
EXW55_12460	COG2318	DinB family
EXW55_12475	COG1162	GTPase activity
EXW55_12480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW55_12485	COG1115	amino acid carrier protein
EXW55_12490	COG1012	belongs to the aldehyde dehydrogenase family
EXW55_12495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW55_12505	COG3938	Belongs to the proline racemase family
EXW55_12510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW55_12550	COG0586	Pfam SNARE associated Golgi protein
EXW55_12565	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW55_12570	COG4166	transmembrane transport
EXW55_12580	COG4948	Mandelate Racemase Muconate Lactonizing
EXW55_12600	COG0667	Aldo Keto reductase
EXW55_12645	COG2936	dipeptidyl-peptidase activity
EXW55_12655	COG0745	RESPONSE REGULATOR receiver
EXW55_12675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW55_12680	COG1164	Oligoendopeptidase f
EXW55_12705	COG1307	EDD domain protein, DegV family
EXW55_12735	COG1335	isochorismatase
EXW55_12750	COG2814	Major facilitator Superfamily
EXW55_12760	COG1664	Polymer-forming cytoskeletal
EXW55_12765	COG0789	Transcriptional regulator
EXW55_12770	COG4533	DNA binding
EXW55_12775	COG2814	Major facilitator Superfamily
EXW55_12775	COG0477	Major facilitator Superfamily
EXW55_12790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW55_12795	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW55_12800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW55_12805	COG0438	transferase activity, transferring glycosyl groups
EXW55_12820	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW55_12825	COG0438	transferase activity, transferring glycosyl groups
EXW55_12830	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW55_12845	COG2261	transglycosylase associated protein
EXW55_12860	COG2226	methyltransferase
EXW55_12895	COG0436	Aminotransferase
EXW55_12900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW55_12925	COG1131	(ABC) transporter
EXW55_12930	COG2188	Transcriptional regulator
EXW55_12975	COG0628	permease
EXW55_13005	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW55_13015	COG0697	spore germination
EXW55_13020	COG2318	DinB family
EXW55_13070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW55_13080	COG2814	Major facilitator Superfamily
EXW55_13085	COG1368	sulfuric ester hydrolase activity
EXW55_13100	COG0488	(ABC) transporter
EXW55_13105	COG1033	growth of symbiont in host cell
EXW55_13105	COG2409	Drug exporters of the RND superfamily
EXW55_13115	COG1309	transcriptional regulator
EXW55_13135	COG0287	Prephenate dehydrogenase
EXW55_13150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW55_13150	COG1605	Chorismate mutase
EXW55_13180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EXW55_13195	COG1388	LysM domain
EXW55_13195	COG3584	3D domain protein
EXW55_13205	COG0346	lactoylglutathione lyase activity
EXW55_13215	COG0431	NADPH-dependent FMN reductase
EXW55_13245	COG0579	oxidoreductase
EXW55_13250	COG1879	ABC-type sugar transport system periplasmic component
EXW55_13265	COG1129	ABC transporter
EXW55_13270	COG2390	Transcriptional regulator
EXW55_13285	COG1830	Aldolase
EXW55_13300	COG0346	lactoylglutathione lyase activity
EXW55_13305	COG2329	Antibiotic biosynthesis monooxygenase
EXW55_13330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW55_13340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW55_13345	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW55_13350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW55_13355	COG3239	Fatty acid desaturase
EXW55_13375	COG3655	Transcriptional regulator
EXW55_13420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW55_13425	COG0346	lactoylglutathione lyase activity
EXW55_13455	COG0714	Associated with various cellular activities
EXW55_13475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW55_13480	COG0753	catalase activity
EXW55_13490	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW55_13515	COG0714	Associated with various cellular activities
EXW55_13525	COG0778	Nitroreductase
EXW55_13530	COG1846	Transcriptional regulator
EXW55_13555	COG3831	ATPase activity
EXW55_13555	COG4884	unkown
EXW55_13565	COG1136	(ABC) transporter
EXW55_13595	COG2207	Transcriptional regulator
EXW55_13600	COG0456	acetyltransferase
EXW55_13615	COG0697	spore germination
EXW55_13620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW55_13625	COG1671	Belongs to the UPF0178 family
EXW55_13645	COG0456	acetyltransferase
EXW55_13645	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW55_13670	COG0730	response to heat
EXW55_13680	COG0833	amino acid
EXW55_13690	COG4335	DNA alkylation repair
EXW55_13720	COG0681	Belongs to the peptidase S26 family
EXW55_13725	COG0768	penicillin binding
EXW55_13735	COG3104	oligopeptide transport
EXW55_13740	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW55_13755	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW55_13760	COG1984	allophanate hydrolase subunit 2
EXW55_13765	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW55_13770	COG1414	Transcriptional regulator
EXW55_13800	COG1960	acyl-CoA dehydrogenase activity
EXW55_13815	COG0346	lactoylglutathione lyase activity
EXW55_13825	COG0640	Transcriptional regulator
EXW55_13840	COG3314	Sporulation integral membrane protein YlbJ
EXW55_13865	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW55_13880	COG3848	Pyruvate phosphate dikinase
EXW55_13880	COG0574	Belongs to the PEP-utilizing enzyme family
EXW55_13910	COG1136	(ABC) transporter
EXW55_13945	COG1073	alpha beta
EXW55_13995	COG5002	protein histidine kinase activity
EXW55_14000	COG0745	RESPONSE REGULATOR receiver
EXW55_14015	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW55_14030	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW55_14035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW55_14040	COG1121	(ABC) transporter
EXW55_14055	COG1999	signal sequence binding
EXW55_14060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW55_14065	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW55_14095	COG0798	PFAM Bile acid sodium symporter
EXW55_14100	COG0346	lactoylglutathione lyase activity
EXW55_14105	COG0640	Transcriptional regulator
EXW55_14125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW55_14125	COG3320	Male sterility
EXW55_14130	COG1309	transcriptional regulator
EXW55_14135	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_14140	COG1522	sequence-specific DNA binding
EXW55_14155	COG0346	lactoylglutathione lyase activity
EXW55_14185	COG2226	methyltransferase
EXW55_14195	COG2814	Major facilitator Superfamily
EXW55_14225	COG0745	RESPONSE REGULATOR receiver
EXW55_14230	COG5002	protein histidine kinase activity
EXW55_14230	COG3850	Histidine kinase
EXW55_14260	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW55_14295	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW55_14315	COG1136	(ABC) transporter
EXW55_14320	COG0577	efflux transmembrane transporter activity
EXW55_14340	COG3850	Histidine kinase
EXW55_14340	COG5002	protein histidine kinase activity
EXW55_14355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW55_14375	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW55_14395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW55_14455	COG2814	Major facilitator Superfamily
EXW55_14480	COG5444	nuclease activity
EXW55_14560	COG2849	repeat protein
EXW55_14565	COG5444	nuclease activity
EXW55_14605	COG0477	Major facilitator Superfamily
EXW55_14620	COG1846	Transcriptional regulator
EXW55_14625	COG2814	Major facilitator Superfamily
EXW55_14640	COG0789	Transcriptional regulator
EXW55_14675	COG1476	TRANSCRIPTIONal
EXW55_14690	COG1288	antiporter activity
EXW55_14695	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW55_14740	COG3718	enzyme involved in inositol metabolism
EXW55_14770	COG0673	inositol 2-dehydrogenase activity
EXW55_14775	COG2814	Major facilitator Superfamily
EXW55_14780	COG1609	Transcriptional regulator
EXW55_14910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW55_14975	COG4187	Peptidase family M20/M25/M40
EXW55_14980	COG1414	Transcriptional regulator
EXW55_14990	COG0833	amino acid
EXW55_15005	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW55_15010	COG2031	fatty acid transporter
EXW55_15020	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW55_15075	COG1288	antiporter activity
EXW55_15080	COG2356	endonuclease I
EXW55_15085	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW55_15105	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW55_15130	COG1785	Belongs to the alkaline phosphatase family
EXW55_15135	COG0778	Nitroreductase
EXW55_15140	COG1733	regulation of RNA biosynthetic process
EXW55_15160	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_15170	COG1131	(ABC) transporter
EXW55_15200	COG1595	DNA-templated transcription, initiation
EXW55_15215	COG1011	Hydrolase
EXW55_15220	COG2365	Tyrosine phosphatase family
EXW55_15240	COG0346	lactoylglutathione lyase activity
EXW55_15245	COG1940	carbohydrate kinase activity
EXW55_15250	COG0738	Major facilitator superfamily
EXW55_15255	COG0110	maltose O-acetyltransferase activity
EXW55_15270	COG0628	permease
EXW55_15275	COG2261	transglycosylase associated protein
EXW55_15310	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW55_15320	COG1253	flavin adenine dinucleotide binding
EXW55_15325	COG0789	Transcriptional regulator
EXW55_15330	COG0697	spore germination
EXW55_15340	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW55_15345	COG3813	Protein conserved in bacteria
EXW55_15350	COG2706	6-phosphogluconolactonase activity
EXW55_15355	COG1070	Carbohydrate kinase
EXW55_15365	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW55_15370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW55_15375	COG4702	Belongs to the UPF0303 family
EXW55_15385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW55_15405	COG0384	phenazine biosynthesis protein PhzF
EXW55_15425	COG0318	PFAM AMP-dependent synthetase and ligase
EXW55_15430	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW55_15435	COG1733	regulation of RNA biosynthetic process
EXW55_15450	COG1191	sigma factor activity
EXW55_15480	COG1876	peptidase activity
EXW55_15525	COG0741	lytic transglycosylase activity
EXW55_15555	COG3850	Histidine kinase
EXW55_15555	COG5002	protein histidine kinase activity
EXW55_15560	COG0745	RESPONSE REGULATOR receiver
EXW55_15580	COG0657	acetylesterase activity
EXW55_15590	COG2814	Major facilitator Superfamily
EXW55_15595	COG1309	transcriptional regulator
EXW55_15605	COG3226	Transcriptional regulator
EXW55_15610	COG1280	lysine exporter protein (LysE YggA)
EXW55_15630	COG0814	amino acid
EXW55_15655	COG1151	hydroxylamine reductase activity
EXW55_15685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW55_15695	COG2072	flavoprotein involved in K transport
EXW55_15735	COG0604	alcohol dehydrogenase
EXW55_15740	COG1113	amino acid transport
EXW55_15750	COG2814	Major facilitator Superfamily
EXW55_15765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW55_15770	COG1012	belongs to the aldehyde dehydrogenase family
EXW55_15780	COG0534	Mate efflux family protein
EXW55_15785	COG1012	belongs to the aldehyde dehydrogenase family
EXW55_15790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW55_15805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW55_15810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW55_15830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW55_15835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW55_15840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW55_15845	COG3739	integral membrane protein
EXW55_15865	COG0583	DNA-binding transcription factor activity
EXW55_15890	COG1193	negative regulation of DNA recombination
EXW55_15910	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW55_15915	COG1164	Oligoendopeptidase f
EXW55_15930	COG4978	Transcriptional regulator
EXW55_15930	COG0789	Transcriptional regulator
EXW55_15940	COG3781	membrane
EXW55_15950	COG2957	Belongs to the agmatine deiminase family
EXW55_15955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW55_15995	COG3973	AAA domain
EXW55_16005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW55_16010	COG0640	Transcriptional regulator
EXW55_16015	COG0604	alcohol dehydrogenase
EXW55_16020	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW55_16030	COG0457	Tetratricopeptide repeat
EXW55_16035	COG2808	Putative FMN-binding domain
EXW55_16040	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW55_16050	COG0277	FAD linked oxidase domain protein
EXW55_16060	COG0825	malonyl-CoA metabolic process
EXW55_16090	COG1285	pathogenesis
EXW55_16100	COG2514	catechol 2,3-dioxygenase activity
EXW55_16105	COG2720	vancomycin resistance protein
EXW55_16130	COG1278	Cold shock
EXW55_16140	COG0716	FMN binding
EXW55_16150	COG0494	nUDIX hydrolase
EXW55_16170	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_16180	COG0165	Argininosuccinate lyase
EXW55_16195	COG4145	pantothenate transmembrane transporter activity
EXW55_16205	COG1012	belongs to the aldehyde dehydrogenase family
EXW55_16210	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_16220	COG1657	PFAM Prenyltransferase squalene oxidase
EXW55_16225	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW55_16230	COG2962	Rard protein
EXW55_16235	COG3326	Membrane
EXW55_16265	COG2226	methyltransferase
EXW55_16270	COG4166	transmembrane transport
EXW55_16275	COG4166	transmembrane transport
EXW55_16280	COG4166	transmembrane transport
EXW55_16285	COG1316	TRANSCRIPTIONal
EXW55_16295	COG1595	DNA-templated transcription, initiation
EXW55_16305	COG1131	(ABC) transporter
EXW55_16325	COG0673	inositol 2-dehydrogenase activity
EXW55_16330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW55_16335	COG0187	DNA topoisomerase II activity
EXW55_16340	COG1832	CoA-binding protein
EXW55_16345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW55_16350	COG0745	RESPONSE REGULATOR receiver
EXW55_16360	COG1328	CTP reductase activity
EXW55_16360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW55_16370	COG4841	protein insertion into membrane
EXW55_16375	COG0824	Thioesterase
EXW55_16400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW55_16420	COG1132	(ABC) transporter
EXW55_16425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW55_16455	COG2211	Major facilitator Superfamily
EXW55_16465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW55_16480	COG0183	Belongs to the thiolase family
EXW55_16485	COG0318	PFAM AMP-dependent synthetase and ligase
EXW55_16490	COG1268	BioY protein
EXW55_16495	COG0318	PFAM AMP-dependent synthetase and ligase
EXW55_16510	COG1396	sequence-specific DNA binding
EXW55_16555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW55_16570	COG5002	protein histidine kinase activity
EXW55_16580	COG0400	carboxylic ester hydrolase activity
EXW55_16585	COG0346	lactoylglutathione lyase activity
EXW55_16595	COG0069	glutamate synthase activity
EXW55_16600	COG1902	pentaerythritol trinitrate reductase activity
EXW55_16610	COG1329	Transcriptional regulator
EXW55_16615	COG0010	Belongs to the arginase family
EXW55_16620	COG1228	amidohydrolase
EXW55_16625	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW55_16630	COG2986	histidine ammonia-lyase
EXW55_16640	COG2226	methyltransferase
EXW55_16670	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW55_16675	COG0785	Cytochrome C biogenesis protein
EXW55_16685	COG1473	amidohydrolase
EXW55_16690	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW55_16695	COG1131	(ABC) transporter
EXW55_16715	COG1346	cytolysis
EXW55_16730	COG0730	response to heat
EXW55_16740	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW55_16740	COG3409	Peptidoglycan-binding domain 1 protein
EXW55_16760	COG1132	(ABC) transporter
EXW55_16765	COG1132	(ABC) transporter
EXW55_16770	COG3763	UPF0154 protein
EXW55_16790	COG3639	organic phosphonate transmembrane transporter activity
EXW55_16800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW55_16805	COG0737	Belongs to the 5'-nucleotidase family
EXW55_16815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW55_16820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW55_16835	COG1695	Transcriptional regulator
EXW55_16840	COG1132	(ABC) transporter
EXW55_16870	COG0367	asparagine synthase
EXW55_16875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW55_16885	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW55_16890	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW55_16900	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW55_16900	COG3420	alginic acid biosynthetic process
EXW55_16905	COG1442	glycosyl transferase family 8
EXW55_16905	COG1216	Glycosyl transferase, family 2
EXW55_16930	COG0438	transferase activity, transferring glycosyl groups
EXW55_16940	COG1215	transferase activity, transferring glycosyl groups
EXW55_16945	COG0438	transferase activity, transferring glycosyl groups
EXW55_16950	COG0438	transferase activity, transferring glycosyl groups
EXW55_16955	COG1086	Polysaccharide biosynthesis protein
EXW55_16960	COG0489	protein tyrosine kinase activity
EXW55_16965	COG3944	biosynthesis protein
EXW55_16970	COG0174	glutamine synthetase
EXW55_16975	COG0789	Transcriptional regulator
EXW55_16980	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW55_16985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW55_16990	COG2860	membrane
EXW55_16995	COG0464	growth
EXW55_17015	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW55_17025	COG1388	LysM domain
EXW55_17025	COG3584	3D domain protein
EXW55_17030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW55_17030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW55_17030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW55_17035	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW55_17040	COG1349	DNA-binding transcription factor activity
EXW55_17045	COG1979	alcohol dehydrogenase
EXW55_17050	COG2322	membrane
EXW55_17060	COG1113	amino acid transport
EXW55_17075	COG1473	amidohydrolase
EXW55_17080	COG1408	metallophosphoesterase
EXW55_17085	COG2116	formate transmembrane transporter activity
EXW55_17100	COG2217	Heavy metal translocating P-type atpase
EXW55_17105	COG2608	mercury ion transmembrane transporter activity
EXW55_17110	COG1937	Protein conserved in bacteria
EXW55_17130	COG2819	hydrolase of the alpha beta superfamily
EXW55_17135	COG1120	ATPase activity
EXW55_17140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW55_17145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW55_17150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW55_17155	COG0708	Exodeoxyribonuclease III
EXW55_17160	COG2169	Transcriptional regulator
EXW55_17165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW55_17170	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW55_17175	COG2706	6-phosphogluconolactonase activity
EXW55_17180	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW55_17185	COG2364	Membrane
EXW55_17195	COG0346	lactoylglutathione lyase activity
EXW55_17200	COG3300	MHYT domain
EXW55_17200	COG5001	Diguanylate cyclase
EXW55_17220	COG1086	Polysaccharide biosynthesis protein
EXW55_17240	COG1346	cytolysis
EXW55_17250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW55_17255	COG0596	Alpha beta hydrolase
EXW55_17255	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW55_17260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW55_17275	COG2188	Transcriptional regulator
EXW55_17280	COG2723	6-phospho-beta-galactosidase activity
EXW55_17285	COG0840	transmembrane signaling receptor activity
EXW55_17295	COG3773	Cell wall hydrolase
EXW55_17305	COG1368	sulfuric ester hydrolase activity
EXW55_17310	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW55_17320	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW55_17330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW55_17335	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW55_17345	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW55_17350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW55_17355	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW55_17360	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW55_17360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW55_17370	COG2359	stage V sporulation protein S
EXW55_17375	COG1692	metallophosphoesterase
EXW55_17380	COG1418	mRNA catabolic process
EXW55_17385	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW55_17390	COG1546	Belongs to the CinA family
EXW55_17390	COG1058	Belongs to the CinA family
EXW55_17395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW55_17400	COG1426	Protein conserved in bacteria
EXW55_17415	COG0300	oxidoreductase activity
EXW55_17420	COG0612	Peptidase, M16
EXW55_17425	COG0612	Peptidase, M16
EXW55_17430	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW55_17435	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW55_17440	COG3845	ABC transporter
EXW55_17445	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW55_17450	COG2188	Transcriptional regulator
EXW55_17455	COG1674	ftsk spoiiie
EXW55_17465	COG0740	serine-type endopeptidase activity
EXW55_17470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW55_17480	COG0527	aspartate kinase activity
EXW55_17485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW55_17490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW55_17620	COG0582	viral genome integration into host DNA
EXW55_17675	COG0305	Participates in initiation and elongation during chromosome replication
EXW55_17725	COG2856	Zn peptidase
EXW55_17740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW55_17745	COG1873	PFAM PRC-barrel domain
EXW55_17750	COG0612	Peptidase, M16
EXW55_17755	COG0726	polysaccharide deacetylase
EXW55_17760	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW55_17770	COG0196	riboflavin kinase activity
EXW55_17780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW55_17785	COG1550	Protein conserved in bacteria
EXW55_17790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW55_17795	COG1358	cellular component organization or biogenesis
EXW55_17800	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW55_17805	COG0195	Participates in both transcription termination and antitermination
EXW55_17810	COG0779	Required for maturation of 30S ribosomal subunits
EXW55_17820	COG0442	prolyl-tRNA aminoacylation
EXW55_17825	COG0750	zinc metalloprotease
EXW55_17835	COG4589	Belongs to the CDS family
EXW55_17845	COG0233	cytoplasmic translational termination
EXW55_17850	COG0528	UMP kinase activity
EXW55_17855	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW55_17860	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW55_17865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW55_17870	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW55_17875	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW55_17880	COG4974	Belongs to the 'phage' integrase family
EXW55_17885	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW55_17890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW55_17895	COG0758	DNA mediated transformation
EXW55_17900	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW55_17905	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW55_17910	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW55_17925	COG0335	large ribosomal subunit rRNA binding
EXW55_17930	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW55_17935	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW55_17940	COG1837	Belongs to the UPF0109 family
EXW55_17950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW55_17955	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EXW55_17960	COG0552	protein localization to endoplasmic reticulum
EXW55_17965	COG1196	nuclear chromosome segregation
EXW55_17970	COG0571	ribonuclease III activity
EXW55_17975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW55_17980	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_17985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW55_17990	COG0416	fatty acid biosynthetic process
EXW55_17995	COG2050	protein possibly involved in aromatic compounds catabolism
EXW55_17995	COG1349	DNA-binding transcription factor activity
EXW55_18000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW55_18005	COG1461	Dihydroxyacetone kinase
EXW55_18010	COG1302	Protein conserved in bacteria
EXW55_18025	COG1564	THIamine pyrophosphokinase
EXW55_18030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW55_18040	COG0515	serine threonine protein kinase
EXW55_18040	COG2815	serine threonine protein kinase
EXW55_18045	COG0631	protein serine/threonine phosphatase activity
EXW55_18050	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW55_18055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW55_18055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW55_18060	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW55_18065	COG0242	peptide deformylase activity
EXW55_18070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW55_18075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW55_18080	COG1758	RNA polymerase activity
EXW55_18095	COG1561	YicC-like family, N-terminal region
EXW55_18100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW55_18115	COG0006	proline dipeptidase activity
EXW55_18135	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW55_18155	COG0167	dihydroorotate dehydrogenase activity
EXW55_18160	COG0543	2 iron, 2 sulfur cluster binding
EXW55_18165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW55_18175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW55_18180	COG0540	Belongs to the ATCase OTCase family
EXW55_18190	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW55_18195	COG0564	pseudouridine synthase activity
EXW55_18200	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW55_18210	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW55_18215	COG3599	regulation of cell shape
EXW55_18220	COG2302	S4 RNA-binding domain
EXW55_18225	COG0762	integral membrane protein
EXW55_18230	COG1799	cell septum assembly
EXW55_18235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW55_18245	COG1873	PFAM PRC-barrel domain
EXW55_18250	COG1191	sigma factor activity
EXW55_18255	COG1191	sigma factor activity
EXW55_18265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW55_18270	COG0849	cell division
EXW55_18275	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW55_18290	COG0772	Belongs to the SEDS family
EXW55_18295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW55_18300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW55_18305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW55_18310	COG0768	penicillin binding
EXW55_18315	COG0768	penicillin binding
EXW55_18325	COG0275	rRNA processing
EXW55_18330	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW55_18335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW55_18340	COG0454	-acetyltransferase
EXW55_18350	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW55_18355	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW55_18465	COG0740	serine-type endopeptidase activity
EXW55_18475	COG4626	Terminase
EXW55_18475	COG1802	Transcriptional regulator
EXW55_18525	COG0582	viral genome integration into host DNA
EXW55_18585	COG2002	toxin-antitoxin pair type II binding
EXW55_18595	COG1484	DNA-dependent DNA replication
EXW55_18615	COG3620	sequence-specific DNA binding
EXW55_18635	COG1396	sequence-specific DNA binding
EXW55_18650	COG0582	viral genome integration into host DNA
EXW55_18655	COG1323	Belongs to the UPF0348 family
EXW55_18660	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW55_18665	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW55_18670	COG3314	Sporulation integral membrane protein YlbJ
EXW55_18680	COG0742	ribosomal rna small subunit methyltransferase
EXW55_18690	COG4471	UPF0298 protein
EXW55_18695	COG3679	Belongs to the UPF0342 family
EXW55_18700	COG0406	alpha-ribazole phosphatase activity
EXW55_18715	COG2340	Cysteine-rich secretory protein family
EXW55_18725	COG3336	cytochrome c oxidase
EXW55_18750	COG0109	protoheme IX farnesyltransferase activity
EXW55_18755	COG1612	heme a metabolic process
EXW55_18760	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW55_18770	COG0772	Belongs to the SEDS family
EXW55_18775	COG4838	Belongs to the UPF0358 family
EXW55_18780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW55_18785	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW55_18795	COG4896	Protein conserved in bacteria
EXW55_18810	COG1217	gtp-binding protein TYPA
EXW55_18820	COG0483	inositol monophosphate 1-phosphatase activity
EXW55_18830	COG4493	Belongs to the UPF0637 family
EXW55_18835	COG4476	Belongs to the UPF0223 family
EXW55_18845	COG1982	Orn Lys Arg decarboxylase major
EXW55_18890	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW55_18895	COG0022	dehydrogenase e1 component
EXW55_18900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW55_18915	COG0561	phosphatase activity
EXW55_18925	COG5503	Protein of unknown function (DUF1447)
EXW55_18930	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW55_18935	COG0569	domain protein
EXW55_18945	COG1473	amidohydrolase
EXW55_18950	COG2171	N-acyltransferase activity
EXW55_18955	COG0583	DNA-binding transcription factor activity
EXW55_18960	COG0517	IMP dehydrogenase activity
EXW55_18970	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW55_18980	COG4703	Protein of unknown function (DUF1797)
EXW55_18995	COG2200	EAL domain
EXW55_19000	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_19005	COG1408	metallophosphoesterase
EXW55_19050	COG2814	Major facilitator Superfamily
EXW55_19060	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW55_19070	COG3209	COG3209 Rhs family protein
EXW55_19080	COG2205	protein histidine kinase activity
EXW55_19090	COG0436	Aminotransferase
EXW55_19095	COG1609	Transcriptional regulator
EXW55_19100	COG3833	ABC-type maltose transport systems, permease component
EXW55_19105	COG1175	transmembrane transport
EXW55_19110	COG2182	Extracellular solute-binding protein
EXW55_19120	COG0366	Alpha amylase catalytic
EXW55_19125	COG3842	ATPase activity
EXW55_19170	COG0183	Belongs to the thiolase family
EXW55_19205	COG1695	Transcriptional regulator
EXW55_19210	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_19220	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW55_19225	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW55_19230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW55_19235	COG0436	Aminotransferase
EXW55_19240	COG1850	ribulose-bisphosphate carboxylase activity
EXW55_19245	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW55_19250	COG0235	Class ii aldolase
EXW55_19255	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW55_19270	COG2084	Dehydrogenase
EXW55_19280	COG2199	diguanylate cyclase activity
EXW55_19285	COG0778	Nitroreductase
EXW55_19310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW55_19310	COG1263	PTS System
EXW55_19310	COG2190	(PTS) system
EXW55_19315	COG3711	transcriptional antiterminator
EXW55_19325	COG2188	Transcriptional regulator
EXW55_19330	COG0363	glucosamine-6-phosphate deaminase activity
EXW55_19335	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW55_19345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW55_19355	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW55_19365	COG1547	Domain of unknown function (DUF309)
EXW55_19375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW55_19380	COG4086	secreted protein
EXW55_19385	COG0561	phosphatase activity
EXW55_19390	COG0697	spore germination
EXW55_19405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW55_19430	COG0733	neurotransmitter:sodium symporter activity
EXW55_19450	COG1686	Belongs to the peptidase S11 family
EXW55_19460	COG1725	Transcriptional regulator
EXW55_19465	COG1131	(ABC) transporter
EXW55_19485	COG1846	Transcriptional regulator
EXW55_19500	COG0598	Magnesium transport protein CorA
EXW55_19515	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW55_19525	COG4974	Belongs to the 'phage' integrase family
EXW55_19535	COG0735	belongs to the Fur family
EXW55_19540	COG1300	Membrane
EXW55_19560	COG0667	Aldo Keto reductase
EXW55_19565	COG0656	L-ascorbic acid biosynthetic process
EXW55_19570	COG0456	acetyltransferase
EXW55_19570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW55_19580	COG4085	toxin activity
EXW55_19580	COG1525	nuclease
EXW55_19580	COG0737	Belongs to the 5'-nucleotidase family
EXW55_19585	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW55_19595	COG0596	Alpha beta hydrolase
EXW55_19600	COG2056	Na+-H+ antiporter family
EXW55_19605	COG1609	Transcriptional regulator
EXW55_19610	COG0456	acetyltransferase
EXW55_19615	COG1073	alpha beta
EXW55_19635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW55_19635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW55_19640	COG0307	riboflavin synthase, alpha
EXW55_19645	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW55_19645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW55_19660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW55_19665	COG4106	trans-aconitate 2-methyltransferase activity
EXW55_19670	COG1073	alpha beta
EXW55_19670	COG2226	methyltransferase
EXW55_19675	COG0156	8-amino-7-oxononanoate synthase activity
EXW55_19685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW55_19695	COG1757	Na H antiporter
EXW55_19700	COG0737	Belongs to the 5'-nucleotidase family
EXW55_19710	COG1522	sequence-specific DNA binding
EXW55_19745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW55_19755	COG0300	oxidoreductase activity
EXW55_19760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW55_19765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW55_19770	COG1760	l-serine dehydratase
EXW55_19775	COG1760	l-serine dehydratase
EXW55_19785	COG1234	tRNA 3'-trailer cleavage
EXW55_19810	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW55_19815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW55_19825	COG1376	ErfK ybiS ycfS ynhG family protein
EXW55_19830	COG4129	membrane
EXW55_19835	COG1126	abc transporter atp-binding protein
EXW55_19840	COG0765	amino acid transport
EXW55_19845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW55_19860	COG2816	NAD+ diphosphatase activity
EXW55_19865	COG2323	membrane
EXW55_19870	COG0772	Belongs to the SEDS family
EXW55_19880	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW55_19885	COG0022	dehydrogenase e1 component
EXW55_19890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW55_19895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW55_19900	COG3426	butyrate kinase activity
EXW55_19910	COG0280	phosphate acetyltransferase
EXW55_19920	COG3290	protein histidine kinase activity
EXW55_19920	COG3829	transcription factor binding
EXW55_19930	COG0584	glycerophosphoryl diester phosphodiesterase
EXW55_19935	COG3093	addiction module antidote protein HigA
EXW55_19975	COG0745	RESPONSE REGULATOR receiver
EXW55_19985	COG0750	zinc metalloprotease
EXW55_19990	COG0497	DNA recombination
EXW55_19995	COG1438	arginine binding
EXW55_20000	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW55_20005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW55_20010	COG0142	geranyltranstransferase activity
EXW55_20015	COG1722	exodeoxyribonuclease VII activity
EXW55_20020	COG1570	exodeoxyribonuclease VII activity
EXW55_20025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW55_20030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW55_20035	COG1302	Protein conserved in bacteria
EXW55_20040	COG0439	Biotin carboxylase
EXW55_20045	COG0511	ligase activity, forming carbon-carbon bonds
EXW55_20090	COG3854	ATPases associated with a variety of cellular activities
EXW55_20110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW55_20115	COG0006	proline dipeptidase activity
EXW55_20120	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW55_20130	COG3872	metal-dependent enzyme
EXW55_20140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW55_20145	COG1321	iron dependent repressor
EXW55_20175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW55_20185	COG1609	Transcriptional regulator
EXW55_20195	COG2076	Multidrug Resistance protein
EXW55_20200	COG2076	Multidrug Resistance protein
EXW55_20235	COG1725	Transcriptional regulator
EXW55_20250	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW55_20255	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW55_20260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW55_20265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW55_20295	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW55_20320	COG4970	Tfp pilus assembly protein FimT
EXW55_20330	COG1459	type II secretion system
EXW55_20335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW55_20390	COG1410	methionine synthase
EXW55_20390	COG0646	methionine synthase
EXW55_20395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW55_20395	COG0646	methionine synthase
EXW55_20400	COG0626	cystathionine gamma-synthase activity
EXW55_20405	COG0626	cystathionine gamma-synthase activity
EXW55_20420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW55_20430	COG1940	carbohydrate kinase activity
EXW55_20435	COG4483	Protein conserved in bacteria
EXW55_20440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW55_20445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW55_20450	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW55_20455	COG0704	Plays a role in the regulation of phosphate uptake
EXW55_20465	COG0581	inorganic phosphate transmembrane transporter activity
EXW55_20470	COG0573	inorganic phosphate transmembrane transporter activity
EXW55_20475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW55_20480	COG0768	penicillin binding
EXW55_20485	COG0477	Major facilitator Superfamily
EXW55_20490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW55_20515	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW55_20520	COG0735	belongs to the Fur family
EXW55_20525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW55_20530	COG1121	(ABC) transporter
EXW55_20535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW55_20545	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW55_20560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW55_20565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW55_20570	COG2384	SAM-dependent methyltransferase
EXW55_20580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW55_20585	COG0358	DNA primase activity
EXW55_20595	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW55_20600	COG0517	IMP dehydrogenase activity
EXW55_20605	COG1381	Involved in DNA repair and RecF pathway recombination
EXW55_20615	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW55_20620	COG0295	cytidine deaminase activity
EXW55_20625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW55_20630	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW55_20635	COG1480	7TM receptor with intracellular HD hydrolase
EXW55_20640	COG1702	phosphate starvation-inducible protein PhoH
EXW55_20655	COG1610	YqeY-like protein
EXW55_20660	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW55_20665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW55_20670	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW55_20680	COG0484	heat shock protein binding
EXW55_20685	COG0443	Heat shock 70 kDa protein
EXW55_20695	COG1420	regulation of RNA biosynthetic process
EXW55_20700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW55_20705	COG1733	regulation of RNA biosynthetic process
EXW55_20710	COG0481	GTPase activity
EXW55_20720	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW55_20725	COG0268	Binds directly to 16S ribosomal RNA
EXW55_20730	COG1466	dna polymerase III delta subunit
EXW55_20740	COG2333	competence protein COMEC
EXW55_20740	COG0658	competence protein
EXW55_20745	COG2131	deaminase
EXW55_20750	COG1555	photosystem II stabilization
EXW55_20750	COG1596	polysaccharide export
EXW55_20755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW55_20760	COG2226	methyltransferase
EXW55_20765	COG0799	negative regulation of ribosome biogenesis
EXW55_20770	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW55_20775	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW55_20780	COG1534	Rna-binding protein
EXW55_20785	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW55_20790	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW55_20795	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW55_20805	COG0688	phosphatidylethanolamine metabolic process
EXW55_20815	COG1595	DNA-templated transcription, initiation
EXW55_20820	COG2357	RelA SpoT domain protein
EXW55_20830	COG1785	Belongs to the alkaline phosphatase family
EXW55_20840	COG2267	carboxylic ester hydrolase activity
EXW55_20875	COG1404	Belongs to the peptidase S8 family
EXW55_20880	COG3186	Phenylalanine-4-hydroxylase
EXW55_20885	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW55_20890	COG2514	catechol 2,3-dioxygenase activity
EXW55_20895	COG2259	Doxx family
EXW55_20935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW55_20945	COG1012	belongs to the aldehyde dehydrogenase family
EXW55_20945	COG1454	alcohol dehydrogenase
EXW55_20950	COG0626	cystathionine gamma-synthase activity
EXW55_20955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW55_20960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW55_20965	COG2226	methyltransferase
EXW55_20980	COG0768	penicillin binding
EXW55_20985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW55_20990	COG0572	uridine kinase
EXW55_20995	COG0826	peptidase U32
EXW55_21000	COG0826	peptidase U32
EXW55_21005	COG4122	O-methyltransferase activity
EXW55_21010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW55_21020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW55_21025	COG4472	Bacterial protein of unknown function (DUF965)
EXW55_21030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW55_21040	COG0628	permease
EXW55_21060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW55_21070	COG0482	sulfurtransferase activity
EXW55_21075	COG1104	cysteine desulfurase activity
EXW55_21080	COG1959	2 iron, 2 sulfur cluster binding
EXW55_21085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW55_21095	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW55_21100	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW55_21110	COG1490	D-aminoacyl-tRNA deacylase activity
EXW55_21115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW55_21120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW55_21125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW55_21125	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW55_21130	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW55_21135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW55_21135	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW55_21145	COG2244	polysaccharide biosynthetic process
EXW55_21150	COG2323	membrane
EXW55_21160	COG1862	Preprotein translocase
EXW55_21165	COG0343	queuine tRNA-ribosyltransferase activity
EXW55_21170	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW55_21180	COG2255	four-way junction helicase activity
EXW55_21185	COG0632	four-way junction helicase activity
EXW55_21190	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW55_21220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW55_21225	COG0157	Belongs to the NadC ModD family
EXW55_21230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW55_21235	COG1104	cysteine desulfurase activity
EXW55_21240	COG1827	regulation of RNA biosynthetic process
EXW55_21245	COG2258	MOSC domain
EXW55_21250	COG0077	Prephenate dehydratase
EXW55_21255	COG0577	efflux transmembrane transporter activity
EXW55_21260	COG0577	efflux transmembrane transporter activity
EXW55_21265	COG1136	(ABC) transporter
EXW55_21270	COG5002	protein histidine kinase activity
EXW55_21275	COG0745	RESPONSE REGULATOR receiver
EXW55_21280	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW55_21285	COG3290	protein histidine kinase activity
EXW55_21295	COG2868	ribosomal protein
EXW55_21305	COG1530	ribonuclease E activity
EXW55_21310	COG1994	Peptidase M50
EXW55_21315	COG0739	heme binding
EXW55_21320	COG2894	cell division
EXW55_21325	COG0850	regulation of cytokinetic process
EXW55_21340	COG1077	Cell shape determining protein MreB Mrl
EXW55_21345	COG2003	Belongs to the UPF0758 family
EXW55_21350	COG0424	maF-like protein
EXW55_21365	COG0285	dihydrofolate synthase activity
EXW55_21380	COG1388	LysM domain
EXW55_21385	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW55_21390	COG0113	porphobilinogen synthase activity
EXW55_21395	COG1587	Uroporphyrinogen-III synthase
EXW55_21400	COG0181	hydroxymethylbilane synthase activity
EXW55_21405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW55_21410	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW55_21415	COG1846	Transcriptional regulator
EXW55_21420	COG1764	response to oxidative stress
EXW55_21425	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW55_21435	COG1067	ATP-dependent peptidase activity
EXW55_21435	COG0470	DNA polymerase III
EXW55_21445	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW55_21505	COG0582	viral genome integration into host DNA
EXW55_21570	COG0622	Phosphoesterase
EXW55_21580	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW55_21585	COG5401	PFAM Sporulation and spore germination
EXW55_21595	COG2197	response regulator
EXW55_21600	COG2233	PERMEase
EXW55_21605	COG0402	S-adenosylhomocysteine deaminase activity
EXW55_21610	COG1983	PspC domain protein
EXW55_21615	COG1396	sequence-specific DNA binding
EXW55_21620	COG0697	spore germination
EXW55_21630	COG1959	2 iron, 2 sulfur cluster binding
EXW55_21635	COG1668	transmembrane transport
EXW55_21640	COG4152	abc transporter atp-binding protein
EXW55_21645	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW55_21650	COG1360	Flagellar Motor Protein
EXW55_21655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW55_21665	COG1876	peptidase activity
EXW55_21670	COG0824	Thioesterase
EXW55_21675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW55_21680	COG1053	succinate dehydrogenase
EXW55_21685	COG2009	succinate dehydrogenase
EXW55_21690	COG1719	4-vinyl reductase, 4VR
EXW55_21695	COG0322	excinuclease ABC activity
EXW55_21700	COG3118	belongs to the thioredoxin family
EXW55_21705	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW55_21710	COG2086	electron transfer activity
EXW55_21715	COG1024	Enoyl-CoA hydratase
EXW55_21720	COG1309	transcriptional regulator
EXW55_21725	COG0318	PFAM AMP-dependent synthetase and ligase
EXW55_21750	COG2318	DinB family
EXW55_21770	COG1131	(ABC) transporter
EXW55_21775	COG2205	protein histidine kinase activity
EXW55_21780	COG0745	RESPONSE REGULATOR receiver
EXW55_21785	COG4895	conserved protein (DUF2196)
EXW55_21790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW55_21800	COG2329	Antibiotic biosynthesis monooxygenase
EXW55_21805	COG4509	Sortase family
EXW55_21810	COG1120	ATPase activity
EXW55_21825	COG5386	Cell surface protein
EXW55_21835	COG5386	Cell surface protein
EXW55_21840	COG1114	Component of the transport system for branched-chain amino acids
EXW55_21850	COG1193	negative regulation of DNA recombination
EXW55_21855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW55_21855	COG1796	DNA polymerase
EXW55_21860	COG1286	toxin biosynthetic process
EXW55_21865	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW55_21870	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW55_21905	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW55_21910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW55_21925	COG1418	mRNA catabolic process
EXW55_21955	COG2814	Major facilitator Superfamily
EXW55_21960	COG1566	PFAM secretion protein HlyD family protein
EXW55_21965	COG1309	transcriptional regulator
EXW55_21970	COG1363	Peptidase, m42
EXW55_21980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW55_21995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW55_22005	COG1484	DNA-dependent DNA replication
EXW55_22010	COG3611	Membrane attachment protein
EXW55_22015	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW55_22020	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW55_22025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW55_22030	COG0237	dephospho-CoA kinase activity
EXW55_22035	COG1971	Probably functions as a manganese efflux pump
EXW55_22045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW55_22045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW55_22050	COG5002	protein histidine kinase activity
EXW55_22055	COG0745	RESPONSE REGULATOR receiver
EXW55_22070	COG0039	L-malate dehydrogenase activity
EXW55_22075	COG0538	isocitrate dehydrogenase activity
EXW55_22080	COG0372	Belongs to the citrate synthase family
EXW55_22100	COG0628	permease
EXW55_22105	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW55_22115	COG0205	6-phosphofructokinase activity
EXW55_22125	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW55_22130	COG1725	Transcriptional regulator
EXW55_22135	COG0281	malic enzyme
EXW55_22140	COG0587	DNA-directed DNA polymerase activity
EXW55_22155	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW55_22175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW55_22185	COG4109	DRTGG domain
EXW55_22190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW55_22195	COG0006	proline dipeptidase activity
EXW55_22220	COG0662	Cupin 2, conserved barrel domain protein
EXW55_22230	COG1476	TRANSCRIPTIONal
EXW55_22245	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_22250	COG0589	response to stress
EXW55_22265	COG0165	Argininosuccinate lyase
EXW55_22270	COG0137	argininosuccinate synthase activity
EXW55_22285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW55_22305	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW55_22310	COG0827	DNA restriction-modification system
EXW55_22315	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW55_22320	COG3874	Sporulation protein YtfJ
EXW55_22335	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW55_22345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW55_22360	COG1104	cysteine desulfurase activity
EXW55_22365	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW55_22375	COG1309	transcriptional regulator
EXW55_22380	COG1956	GAF domain-containing protein
EXW55_22385	COG0626	cystathionine gamma-synthase activity
EXW55_22390	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW55_22430	COG1595	DNA-templated transcription, initiation
EXW55_22440	COG0110	maltose O-acetyltransferase activity
EXW55_22445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW55_22450	COG0454	-acetyltransferase
EXW55_22455	COG0517	IMP dehydrogenase activity
EXW55_22460	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW55_22475	COG0745	RESPONSE REGULATOR receiver
EXW55_22485	COG0666	response to abiotic stimulus
EXW55_22495	COG1970	mechanosensitive ion channel activity
EXW55_22520	COG1609	Transcriptional regulator
EXW55_22525	COG1605	Chorismate mutase
EXW55_22525	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW55_22530	COG1605	Chorismate mutase
EXW55_22530	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW55_22535	COG4851	CamS sex pheromone cAM373 precursor
EXW55_22540	COG3118	belongs to the thioredoxin family
EXW55_22550	COG2309	aminopeptidase activity
EXW55_22570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW55_22575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW55_22585	COG1674	ftsk spoiiie
EXW55_22600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW55_22605	COG4848	Belongs to the UPF0354 family
EXW55_22610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW55_22615	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW55_22620	COG1363	Peptidase, m42
EXW55_22630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW55_22635	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW55_22645	COG0510	thiamine kinase activity
EXW55_22650	COG1523	belongs to the glycosyl hydrolase 13 family
EXW55_22660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW55_22665	COG1349	DNA-binding transcription factor activity
EXW55_22670	COG1187	pseudouridine synthase activity
EXW55_22675	COG2244	polysaccharide biosynthetic process
EXW55_22680	COG2081	HI0933 family
EXW55_22685	COG2814	Major facilitator Superfamily
EXW55_22695	COG3832	glyoxalase III activity
EXW55_22715	COG1329	Transcriptional regulator
EXW55_22740	COG0314	molybdopterin synthase activity
EXW55_22745	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW55_22750	COG0303	'Molybdopterin
EXW55_22755	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW55_22760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW55_22765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW55_22790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW55_22800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW55_22840	COG0495	leucyl-tRNA aminoacylation
EXW55_22845	COG2814	Major facilitator Superfamily
EXW55_22850	COG0475	glutathione-regulated potassium exporter activity
EXW55_22855	COG0490	domain, Protein
EXW55_22860	COG0582	viral genome integration into host DNA
EXW55_22875	COG1136	(ABC) transporter
EXW55_22895	COG1242	4 iron, 4 sulfur cluster binding
EXW55_22900	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW55_22920	COG2267	carboxylic ester hydrolase activity
EXW55_22925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW55_22930	COG0671	phosphoesterase, PA-phosphatase related
EXW55_22935	COG0438	transferase activity, transferring glycosyl groups
EXW55_22940	COG0746	molybdenum cofactor guanylyltransferase activity
EXW55_22960	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW55_22965	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW55_23005	COG5002	protein histidine kinase activity
EXW55_23010	COG3852	Histidine kinase
EXW55_23015	COG0753	catalase activity
EXW55_23020	COG2267	carboxylic ester hydrolase activity
EXW55_23030	COG1368	sulfuric ester hydrolase activity
EXW55_23040	COG4895	conserved protein (DUF2196)
EXW55_23055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW55_23060	COG1116	anion transmembrane transporter activity
EXW55_23065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW55_23085	COG0494	nUDIX hydrolase
EXW55_23125	COG2076	Multidrug Resistance protein
EXW55_23130	COG2076	Multidrug Resistance protein
EXW55_23135	COG0789	Transcriptional regulator
EXW55_23140	COG1854	S-ribosylhomocysteine lyase activity
EXW55_23150	COG0288	reversible hydration of carbon dioxide
EXW55_23155	COG1271	oxidase subunit
EXW55_23160	COG1294	oxidase, subunit
EXW55_23185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW55_23210	COG1842	Phage shock protein A
EXW55_23235	COG3859	Proton-coupled thiamine transporter YuaJ
EXW55_23240	COG5002	protein histidine kinase activity
EXW55_23245	COG0745	RESPONSE REGULATOR receiver
EXW55_23270	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW55_23275	COG1597	lipid kinase activity
EXW55_23315	COG5002	protein histidine kinase activity
EXW55_23325	COG0586	Pfam SNARE associated Golgi protein
EXW55_23340	COG0577	efflux transmembrane transporter activity
EXW55_23345	COG1136	(ABC) transporter
EXW55_23350	COG2207	Transcriptional regulator
EXW55_23350	COG3708	Transcriptional regulator
EXW55_23360	COG1131	(ABC) transporter
EXW55_23365	COG5658	integral membrane protein
EXW55_23370	COG0640	Transcriptional regulator
EXW55_23375	COG0745	RESPONSE REGULATOR receiver
EXW55_23380	COG2205	protein histidine kinase activity
EXW55_23385	COG0577	efflux transmembrane transporter activity
EXW55_23390	COG0577	efflux transmembrane transporter activity
EXW55_23395	COG1136	(ABC) transporter
EXW55_23400	COG0577	efflux transmembrane transporter activity
EXW55_23415	COG2188	Transcriptional regulator
EXW55_23435	COG3964	amidohydrolase
EXW55_23455	COG4948	Mandelate Racemase Muconate Lactonizing
EXW55_23460	COG0318	PFAM AMP-dependent synthetase and ligase
EXW55_23465	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW55_23470	COG0596	Alpha beta hydrolase
EXW55_23475	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW55_23480	COG1169	isochorismate synthase
EXW55_23485	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW55_23490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW55_23495	COG1278	Cold shock
EXW55_23505	COG0789	Transcriptional regulator
EXW55_23520	COG0058	SHG alpha-glucan phosphorylase activity
EXW55_23530	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW55_23535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW55_23540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW55_23550	COG1404	Belongs to the peptidase S8 family
EXW55_23690	COG1285	pathogenesis
EXW55_23695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW55_23705	COG0166	Belongs to the GPI family
EXW55_23715	COG2155	Conserved Protein
EXW55_23720	COG1098	S1 RNA binding domain
EXW55_23725	COG0436	Aminotransferase
EXW55_23730	COG1522	sequence-specific DNA binding
EXW55_23735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW55_23740	COG2267	carboxylic ester hydrolase activity
EXW55_23750	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW55_23765	COG5018	Exonuclease
EXW55_23770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW55_23790	COG2050	protein possibly involved in aromatic compounds catabolism
EXW55_23800	COG1268	BioY protein
EXW55_23805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW55_23810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW55_23820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW55_23825	COG3584	3D domain protein
EXW55_23840	COG1252	NADH dehydrogenase
EXW55_23845	COG0492	ferredoxin-NADP+ reductase activity
EXW55_23850	COG3708	Transcriptional regulator
EXW55_23865	COG1683	Conserved Protein
EXW55_23890	COG0316	Belongs to the HesB IscA family
EXW55_23895	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW55_23900	COG4844	belongs to the
EXW55_23905	COG1252	NADH dehydrogenase
EXW55_23915	COG0390	transport system, permease component
EXW55_23920	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW55_23960	COG4837	Protein of unknown function (DUF1462)
EXW55_23965	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW55_23975	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW55_23980	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW55_23995	COG1136	(ABC) transporter
EXW55_23995	COG0577	efflux transmembrane transporter activity
EXW55_24000	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW55_24010	COG0647	UMP catabolic process
EXW55_24020	COG2445	Protein of unknown function DUF86
EXW55_24025	COG1494	fructose-1,6-bisphosphatase
EXW55_24040	COG4470	Protein conserved in bacteria
EXW55_24050	COG0789	Transcriptional regulator
EXW55_24055	COG4377	Putative membrane peptidase family (DUF2324)
EXW55_24075	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW55_24080	COG0739	heme binding
EXW55_24090	COG3377	Domain of unknown function (DUF1805)
EXW55_24095	COG0737	Belongs to the 5'-nucleotidase family
EXW55_24105	COG0719	Fe-S assembly protein
EXW55_24110	COG0822	iron-sulfur transferase activity
EXW55_24115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW55_24120	COG0719	Fe-S assembly protein
EXW55_24125	COG0396	ATPase activity
EXW55_24130	COG1464	Belongs to the NlpA lipoprotein family
EXW55_24135	COG1464	Belongs to the NlpA lipoprotein family
EXW55_24140	COG2011	ABC-type metal ion transport system permease component
EXW55_24155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW55_24160	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW55_24170	COG0509	glycine decarboxylation via glycine cleavage system
EXW55_24175	COG1393	Belongs to the ArsC family
EXW55_24210	COG1309	transcriptional regulator
EXW55_24215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW55_24220	COG1960	acyl-CoA dehydrogenase activity
EXW55_24225	COG0183	Belongs to the thiolase family
EXW55_24230	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW55_24230	COG1024	Enoyl-CoA hydratase
EXW55_24240	COG1686	Belongs to the peptidase S11 family
EXW55_24245	COG0506	proline dehydrogenase activity
EXW55_24255	COG0011	TIGRFAM Protein of
EXW55_24260	COG0840	transmembrane signaling receptor activity
EXW55_24275	COG2814	Major facilitator Superfamily
EXW55_24280	COG0531	amino acid
EXW55_24310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW55_24370	COG0586	Pfam SNARE associated Golgi protein
EXW55_24380	COG1376	ErfK ybiS ycfS ynhG family protein
EXW55_24385	COG0745	RESPONSE REGULATOR receiver
EXW55_24390	COG5002	protein histidine kinase activity
EXW55_24400	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW55_24410	COG0840	transmembrane signaling receptor activity
EXW55_24415	COG0840	transmembrane signaling receptor activity
EXW55_24420	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW55_24425	COG3227	Zinc metalloprotease (Elastase)
EXW55_24430	COG1741	Belongs to the pirin family
EXW55_24450	COG0475	glutathione-regulated potassium exporter activity
EXW55_24455	COG0490	domain, Protein
EXW55_24460	COG1115	amino acid carrier protein
EXW55_24465	COG0783	Belongs to the Dps family
EXW55_24475	COG2318	DinB family
EXW55_24480	COG1611	Belongs to the LOG family
EXW55_24490	COG1528	Iron-storage protein
EXW55_24495	COG2311	Membrane
EXW55_24500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW55_24505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW55_24510	COG1115	amino acid carrier protein
EXW55_24515	COG1115	amino acid carrier protein
EXW55_24520	COG2910	NAD(P)H-binding
EXW55_24550	COG0656	L-ascorbic acid biosynthetic process
EXW55_24555	COG2814	Major facilitator Superfamily
EXW55_24560	COG1733	regulation of RNA biosynthetic process
EXW55_24570	COG1252	NADH dehydrogenase
EXW55_24590	COG3290	protein histidine kinase activity
EXW55_24590	COG0840	transmembrane signaling receptor activity
EXW55_24615	COG3655	Transcriptional regulator
EXW55_24630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW55_24640	COG1733	regulation of RNA biosynthetic process
EXW55_24645	COG0778	Nitroreductase
EXW55_24650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW55_24655	COG4224	UPF0291 protein
EXW55_24660	COG1522	sequence-specific DNA binding
EXW55_24665	COG0288	reversible hydration of carbon dioxide
EXW55_24670	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW55_24675	COG2233	PERMEase
EXW55_24720	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW55_24730	COG0557	exoribonuclease II activity
EXW55_24735	COG1647	Serine aminopeptidase, S33
EXW55_24740	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW55_24745	COG1346	cytolysis
EXW55_24760	COG0148	phosphopyruvate hydratase activity
EXW55_24770	COG0149	triose-phosphate isomerase activity
EXW55_24775	COG0126	phosphoglycerate kinase activity
EXW55_24780	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW55_24795	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW55_24820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW55_24835	COG2323	membrane
EXW55_24845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW55_24850	COG1481	regulation of sporulation
EXW55_24855	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW55_24860	COG1660	Displays ATPase and GTPase activities
EXW55_24865	COG1051	belongs to the nudix hydrolase family
EXW55_24875	COG0492	ferredoxin-NADP+ reductase activity
EXW55_24880	COG0457	Tetratricopeptide repeat
EXW55_24885	COG0110	maltose O-acetyltransferase activity
EXW55_24890	COG0546	phosphoglycolate phosphatase activity
EXW55_24895	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW55_24900	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW55_24905	COG1950	PFAM Membrane protein of
EXW55_24915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW55_24935	COG0789	Transcriptional regulator
EXW55_24970	COG0583	DNA-binding transcription factor activity
EXW55_24975	COG0789	Transcriptional regulator
EXW55_24980	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW55_24985	COG0488	(ABC) transporter
EXW55_25000	COG1132	(ABC) transporter
EXW55_25005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW55_25010	COG3409	Peptidoglycan-binding domain 1 protein
EXW55_25010	COG0793	Belongs to the peptidase S41A family
EXW55_25015	COG2177	Part of the ABC transporter FtsEX involved in
EXW55_25020	COG2884	Cell division ATP-binding protein ftsE
EXW55_25055	COG1131	(ABC) transporter
EXW55_25090	COG1278	Cold shock
EXW55_25095	COG1040	competence protein
EXW55_25100	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW55_25105	COG0791	NLP P60 protein
EXW55_25105	COG1388	LysM domain
EXW55_25110	COG1733	regulation of RNA biosynthetic process
EXW55_25115	COG1307	EDD domain protein, DegV family
EXW55_25120	COG1739	Uncharacterized protein family UPF0029
EXW55_25125	COG1316	TRANSCRIPTIONal
EXW55_25130	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW55_25135	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW55_25140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW55_25150	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW55_25150	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW55_25170	COG1486	melibiose metabolic process
EXW55_25175	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW55_25180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW55_25200	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW55_25210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW55_25215	COG1301	dicarboxylic acid transport
EXW55_25230	COG1511	domain protein
EXW55_25235	COG0583	DNA-binding transcription factor activity
EXW55_25240	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW55_25245	COG1271	oxidase subunit
EXW55_25250	COG1294	oxidase, subunit
EXW55_25255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW55_25260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW55_25265	COG1620	l-lactate permease
EXW55_25275	COG2389	metal-binding protein
EXW55_25290	COG1368	sulfuric ester hydrolase activity
EXW55_25300	COG0791	NLP P60 protein
EXW55_25300	COG1388	LysM domain
EXW55_25305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW55_25315	COG1215	transferase activity, transferring glycosyl groups
EXW55_25320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW55_25330	COG3584	3D domain protein
EXW55_25330	COG1388	LysM domain
EXW55_25355	COG4715	Zinc finger, swim domain protein
EXW55_25360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW55_25400	COG0577	efflux transmembrane transporter activity
EXW55_25405	COG1136	(ABC) transporter
EXW55_25440	COG5002	protein histidine kinase activity
EXW55_25440	COG3850	Histidine kinase
EXW55_25445	COG0745	RESPONSE REGULATOR receiver
EXW55_25455	COG1316	TRANSCRIPTIONal
EXW55_25460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW55_25465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW55_25470	COG1215	transferase activity, transferring glycosyl groups
EXW55_25475	COG0438	transferase activity, transferring glycosyl groups
EXW55_25495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW55_25500	COG4464	protein tyrosine phosphatase activity
EXW55_25505	COG0489	protein tyrosine kinase activity
EXW55_25510	COG3944	biosynthesis protein
EXW55_25515	COG0489	protein tyrosine kinase activity
EXW55_25530	COG1609	Transcriptional regulator
EXW55_25540	COG0739	heme binding
EXW55_25555	COG3279	Response regulator of the LytR AlgR family
EXW55_25560	COG2385	sporulation resulting in formation of a cellular spore
EXW55_25575	COG4836	Membrane
EXW55_25580	COG1007	ATP synthesis coupled electron transport
EXW55_25585	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW55_25590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW55_25595	COG0713	ATP synthesis coupled electron transport
EXW55_25600	COG0839	Belongs to the complex I subunit 6 family
EXW55_25610	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW55_25615	COG0649	NAD binding
EXW55_25620	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW55_25625	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW55_25630	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW55_25635	COG5001	Diguanylate cyclase
EXW55_25635	COG3300	MHYT domain
EXW55_25650	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW55_25655	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW55_25660	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW55_25665	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW55_25670	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW55_25675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW55_25685	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW55_25710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW55_25720	COG0698	ribose 5-phosphate isomerase
EXW55_25730	COG2190	(PTS) system
EXW55_25735	COG2259	Doxx family
EXW55_25740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW55_25750	COG1971	Probably functions as a manganese efflux pump
EXW55_25755	COG0009	L-threonylcarbamoyladenylate synthase
EXW55_25770	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW55_25775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW55_25780	COG1435	thymidine kinase activity
EXW55_25790	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW55_25800	COG1494	fructose-1,6-bisphosphatase
EXW55_25820	COG4821	SIS domain
EXW55_25825	COG0504	CTP synthase activity
EXW55_25830	COG3343	RNA polymerase activity
EXW55_25840	COG1960	acyl-CoA dehydrogenase activity
EXW55_25845	COG1960	acyl-CoA dehydrogenase activity
EXW55_25850	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW55_25855	COG0183	Belongs to the thiolase family
EXW55_25860	COG2181	nitrate reductase activity
EXW55_25860	COG0247	lactate metabolic process
EXW55_25865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW55_25870	COG4294	response to UV
EXW55_25875	COG5001	Diguanylate cyclase
EXW55_25875	COG3300	MHYT domain
EXW55_25890	COG3227	Zinc metalloprotease (Elastase)
EXW55_25895	COG2197	response regulator
EXW55_25900	COG4585	Histidine kinase
EXW55_25905	COG0842	Transport permease protein
EXW55_25910	COG1131	(ABC) transporter
EXW55_25915	COG0024	Methionine aminopeptidase
EXW55_25945	COG2234	aminopeptidase activity
EXW55_25960	COG4506	Protein conserved in bacteria
EXW55_25965	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW55_25980	COG0010	Belongs to the arginase family
EXW55_25985	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW55_25990	COG2814	Major facilitator Superfamily
EXW55_25995	COG0789	Transcriptional regulator
EXW55_26000	COG0584	glycerophosphoryl diester phosphodiesterase
EXW55_26005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW55_26015	COG1994	Peptidase M50
EXW55_26025	COG1078	dGTPase activity
EXW55_26030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW55_26035	COG1120	ATPase activity
EXW55_26040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW55_26045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW55_26050	COG4844	belongs to the
EXW55_26065	COG0280	phosphate acetyltransferase
EXW55_26070	COG3253	May function as heme-dependent peroxidase
EXW55_26080	COG3773	Cell wall hydrolase
EXW55_26090	COG2363	Small membrane protein
EXW55_26105	COG2233	PERMEase
EXW55_26110	COG0561	phosphatase activity
EXW55_26115	COG2814	Major facilitator Superfamily
EXW55_26120	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW55_26125	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW55_26130	COG1131	(ABC) transporter
EXW55_26135	COG2755	lipolytic protein G-D-S-L family
EXW55_26140	COG1609	Transcriptional regulator
EXW55_26150	COG0460	homoserine dehydrogenase
EXW55_26155	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW55_26160	COG2873	o-acetylhomoserine
EXW55_26175	COG2197	response regulator
EXW55_26180	COG4585	Histidine kinase
EXW55_26180	COG2203	Gaf domain
EXW55_26185	COG0351	phosphomethylpyrimidine kinase
EXW55_26190	COG3706	GGDEF domain
EXW55_26195	COG2879	small protein
EXW55_26200	COG1966	Carbon starvation protein
EXW55_26205	COG3279	Response regulator of the LytR AlgR family
EXW55_26210	COG0477	Major facilitator Superfamily
EXW55_26240	COG0840	transmembrane signaling receptor activity
EXW55_26250	COG1607	acyl-coa hydrolase
EXW55_26255	COG1216	Glycosyl transferase, family 2
EXW55_26270	COG1216	Glycosyl transferase, family 2
EXW55_26280	COG0488	(ABC) transporter
EXW55_26285	COG1309	transcriptional regulator
EXW55_26290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW55_26295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW55_26295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW55_26300	COG0628	permease
EXW55_26310	COG1380	Effector of murein hydrolase LrgA
EXW55_26315	COG3279	Response regulator of the LytR AlgR family
EXW55_26320	COG3275	phosphorelay sensor kinase activity
EXW55_26325	COG2814	Major facilitator Superfamily
EXW55_26330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW55_26335	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW55_26345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW55_26395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW55_26400	COG1272	protein, Hemolysin III
EXW55_26425	COG1164	Oligoendopeptidase f
EXW55_26440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW55_26450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW55_26455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW55_26460	COG4853	Protein conserved in bacteria
EXW55_26470	COG5002	protein histidine kinase activity
EXW55_26475	COG0745	RESPONSE REGULATOR receiver
EXW55_26505	COG0305	Participates in initiation and elongation during chromosome replication
EXW55_26510	COG0359	binds to the 23S rRNA
EXW55_26515	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW55_26520	COG4241	membrane
EXW55_26530	COG0629	single-stranded DNA binding
EXW55_26535	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW55_26540	COG0012	GTP binding
EXW55_26545	COG4481	Protein conserved in bacteria
EXW55_26550	COG0668	transmembrane transport
EXW55_26560	COG1475	DNA binding
EXW55_26565	COG1192	Involved in chromosome partitioning
EXW55_26570	COG1475	DNA binding
EXW55_26575	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW55_26580	COG0445	tRNA wobble uridine modification
EXW55_26585	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW55_26590	COG1847	R3H domain protein
EXW55_26595	COG0706	membrane insertase activity
EXW55_26600	COG0594	ribonuclease P activity
EXW55_26605	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW55_26610	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW55_26615	COG0592	DNA-directed DNA polymerase activity
EXW55_26620	COG2501	S4 domain
EXW55_26625	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW55_26630	COG0187	DNA topoisomerase II activity
EXW55_26635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW55_26670	COG0517	IMP dehydrogenase activity
EXW55_26670	COG0516	GMP reductase activity
EXW55_26675	COG1686	Belongs to the peptidase S11 family
EXW55_26680	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW55_26685	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW55_26705	COG1428	Deoxynucleoside kinase
EXW55_26710	COG1428	Deoxynucleoside kinase
EXW55_26715	COG1335	isochorismatase
EXW55_26720	COG0590	tRNA wobble adenosine to inosine editing
EXW55_26730	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW55_26735	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW55_26740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW55_26785	COG1982	Orn Lys Arg decarboxylase major
EXW55_26790	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW55_26795	COG0470	DNA polymerase III
EXW55_26800	COG1774	PSP1 C-terminal conserved region
EXW55_26805	COG4467	Involved in initiation control of chromosome replication
EXW55_26810	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW55_26820	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW55_26825	COG2002	toxin-antitoxin pair type II binding
EXW55_26835	COG0084	hydrolase, TatD family'
EXW55_26845	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW55_26855	COG4466	Protein conserved in bacteria
EXW55_26865	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW55_26870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW55_26875	COG0251	oxidation-reduction process
EXW55_26880	COG2088	sporulation resulting in formation of a cellular spore
EXW55_26885	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW55_26905	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW55_26910	COG2002	toxin-antitoxin pair type II binding
EXW55_26915	COG2244	polysaccharide biosynthetic process
EXW55_26920	COG3956	TIGRFAM MazG family protein
EXW55_26925	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW55_26945	COG1098	S1 RNA binding domain
EXW55_26960	COG2208	phosphoserine phosphatase activity
EXW55_26970	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW55_26975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW55_26980	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW55_26985	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW55_26990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW55_26995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW55_27000	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW55_27005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW55_27010	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW55_27015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW55_27020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW55_27025	COG1396	sequence-specific DNA binding
EXW55_27030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW55_27035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW55_27125	COG3880	PFAM UvrB UvrC protein
EXW55_27130	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW55_27135	COG0542	response to heat
EXW55_27140	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW55_27145	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW55_27150	COG4956	integral membrane protein (PIN domain superfamily)
EXW55_27155	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW55_27165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW55_27170	COG1045	serine acetyltransferase
EXW55_27175	COG0215	cysteine-tRNA ligase activity
EXW55_27185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW55_27190	COG3688	RNA-binding protein containing a PIN domain
EXW55_27200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW55_27205	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW55_27210	COG0250	Participates in transcription elongation, termination and antitermination
EXW55_27215	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW55_27220	COG0081	regulation of translation
EXW55_27225	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW55_27230	COG0222	ribosome binding
EXW55_27235	COG2813	Specifically methylates the guanine in position
EXW55_27240	COG0085	RNA polymerase activity
EXW55_27245	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW55_27250	COG1358	cellular component organization or biogenesis
EXW55_27255	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW55_27265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW55_27270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW55_27275	COG0051	transcription antitermination factor activity, RNA binding
EXW55_27280	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW55_27285	COG0088	Forms part of the polypeptide exit tunnel
EXW55_27290	COG0089	rRNA binding
EXW55_27295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW55_27300	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW55_27305	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW55_27320	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW55_27325	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW55_27335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW55_27340	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW55_27350	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW55_27360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW55_27370	COG1841	ribosomal large subunit assembly
EXW55_27375	COG0200	Binds to the 23S rRNA
EXW55_27380	COG0201	protein transport
EXW55_27385	COG0563	adenylate kinase activity
EXW55_27390	COG0024	Methionine aminopeptidase
EXW55_27400	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW55_27405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW55_27410	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW55_27435	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW55_27445	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW55_27450	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW55_27460	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW55_27465	COG0489	protein tyrosine kinase activity
EXW55_27475	COG2194	sulfuric ester hydrolase activity
EXW55_27490	COG0726	polysaccharide deacetylase
EXW55_27570	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW55_27575	COG4856	YbbR-like protein
EXW55_27580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW55_27595	COG0823	Involved in the tonB-independent uptake of proteins
EXW55_27595	COG4946	Tricorn protease homolog
EXW55_27595	COG1506	peptidase
EXW55_27605	COG1028	Short-chain dehydrogenase reductase Sdr
EXW55_27610	COG2011	ABC-type metal ion transport system permease component
EXW55_27620	COG1464	Belongs to the NlpA lipoprotein family
EXW55_27625	COG0604	alcohol dehydrogenase
EXW55_27635	COG0277	FAD linked oxidase domain protein
EXW55_27640	COG2271	Major facilitator Superfamily
EXW55_27650	COG2814	Major facilitator Superfamily
EXW55_27665	COG0601	transmembrane transport
EXW55_27670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW55_27675	COG0444	Belongs to the ABC transporter superfamily
EXW55_27680	COG4608	Belongs to the ABC transporter superfamily
EXW55_27685	COG4166	transmembrane transport
EXW55_27695	COG2207	Transcriptional regulator
EXW55_27710	COG4166	transmembrane transport
EXW55_27715	COG4166	transmembrane transport
EXW55_27720	COG0656	L-ascorbic acid biosynthetic process
EXW55_27725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW55_27740	COG4149	molybdate abc transporter
EXW55_27745	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW55_27750	COG1910	domain protein
EXW55_27765	COG0697	spore germination
EXW55_27780	COG0204	Acyl-transferase
EXW55_27790	COG1609	Transcriptional regulator
EXW55_27800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW55_27815	COG5298	Protein conserved in bacteria
EXW55_27840	COG0488	(ABC) transporter
EXW55_27850	COG0747	negative chemotaxis
EXW55_27860	COG0601	transmembrane transport
EXW55_27865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW55_27870	COG0444	Belongs to the ABC transporter superfamily
EXW55_27875	COG4608	Belongs to the ABC transporter superfamily
EXW55_27880	COG0561	phosphatase activity
EXW55_27910	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW55_27915	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW55_27925	COG0531	amino acid
EXW55_27930	COG2814	Major facilitator Superfamily
EXW55_27940	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW55_27950	COG4294	response to UV
EXW55_27955	COG0705	Rhomboid family
EXW55_27960	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW55_27965	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW55_27970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW55_27975	COG0864	Transcriptional regulator
EXW55_27980	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW55_27985	COG2183	response to ionizing radiation
EXW55_28085	COG0802	atpase or kinase
EXW55_28090	COG1214	PFAM Peptidase M22, glycoprotease
EXW55_28095	COG0456	acetyltransferase
EXW55_28105	COG0488	(ABC) transporter
EXW55_28110	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW55_28120	COG1266	CAAX protease self-immunity
EXW55_28125	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW55_28130	COG0459	protein refolding
EXW55_28135	COG0519	Catalyzes the synthesis of GMP from XMP
EXW55_28135	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW55_28140	COG2252	PERMEase
EXW55_28150	COG5002	protein histidine kinase activity
EXW55_28180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW55_28210	COG2226	methyltransferase
EXW55_28230	COG1215	transferase activity, transferring glycosyl groups
EXW55_28255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW55_28260	COG0506	proline dehydrogenase activity
EXW55_28285	COG0697	spore germination
EXW55_28315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW55_28320	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW55_28325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW55_28330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW55_28335	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW55_28340	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW55_28345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW55_28350	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW55_28355	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW55_28360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW55_28365	COG0138	bifunctional purine biosynthesis protein purh
EXW55_28370	COG0151	Belongs to the GarS family
EXW55_28395	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW55_28400	COG0210	DNA helicase
EXW55_28405	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW55_28410	COG4851	CamS sex pheromone cAM373 precursor
EXW55_28420	COG1012	belongs to the aldehyde dehydrogenase family
EXW55_28425	COG1335	isochorismatase
EXW55_28435	COG2011	ABC-type metal ion transport system permease component
EXW55_28440	COG1464	Belongs to the NlpA lipoprotein family
EXW55_28455	COG0003	Pfam Anion-transporting ATPase
EXW55_28460	COG1846	Transcriptional regulator
EXW55_28465	COG4682	membrane
EXW55_28475	COG0154	amidase activity
EXW55_28480	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW55_28485	COG1597	lipid kinase activity
EXW55_28495	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW55_28510	COG1012	belongs to the aldehyde dehydrogenase family
EXW55_28515	COG2076	Multidrug Resistance protein
EXW55_28520	COG2309	aminopeptidase activity
EXW55_28535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW55_28545	COG0582	viral genome integration into host DNA
EXW55_28620	COG2002	toxin-antitoxin pair type II binding
EXW55_28685	COG0582	viral genome integration into host DNA
EXW55_28830	COG0457	Tetratricopeptide repeat
EXW55_28915	COG0741	lytic transglycosylase activity
EXW55_28915	COG0791	NLP P60 protein
EXW55_28950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW55_28950	COG0551	DNA topoisomerase type I activity
EXW55_29020	COG4974	Belongs to the 'phage' integrase family
EXW55_29045	COG2002	toxin-antitoxin pair type II binding
EXW55_29050	COG1923	regulation of RNA biosynthetic process
EXW55_29130	COG2002	toxin-antitoxin pair type II binding
EXW55_29170	COG2311	Membrane
EXW55_29390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW55_29465	COG4712	double-strand break repair protein
EXW55_29470	COG0592	DNA-directed DNA polymerase activity
EXW55_29670	COG0457	Tetratricopeptide repeat
EXW55_29675	COG1361	Conserved repeat domain
EXW55_29680	COG1361	Conserved repeat domain
EXW55_29685	COG1361	Conserved repeat domain
EXW55_29710	COG4974	Belongs to the 'phage' integrase family
EXW55_29785	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW55_29800	COG4166	transmembrane transport
EXW55_29810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW55_29855	COG0457	Tetratricopeptide repeat
EXW55_29865	COG0582	viral genome integration into host DNA
EXW55_29885	COG0791	NLP P60 protein
EXW55_29885	COG0741	lytic transglycosylase activity
EXW55_29900	COG0433	COG0433 Predicted ATPase
EXW55_29990	COG2873	o-acetylhomoserine
EXW55_30010	COG2368	4-hydroxyphenylacetate
EXW55_30030	COG1923	regulation of RNA biosynthetic process
EXW55_30120	COG1278	Cold shock
EXW55_30210	COG1192	Involved in chromosome partitioning
EXW55_30310	COG0823	Involved in the tonB-independent uptake of proteins
EXW55_30380	COG0745	RESPONSE REGULATOR receiver
EXW55_30390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW55_30400	COG0577	efflux transmembrane transporter activity
EXW55_30405	COG1136	(ABC) transporter
EXW55_30415	COG0582	viral genome integration into host DNA
EXW55_30455	COG2002	toxin-antitoxin pair type II binding
EXW55_30545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW55_30555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW55_30560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW55_30565	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW55_30570	COG0697	spore germination
EXW55_30580	COG2002	toxin-antitoxin pair type II binding
EXW55_30585	COG1923	regulation of RNA biosynthetic process
EXW55_30615	COG1114	Component of the transport system for branched-chain amino acids
EXW55_30625	COG1115	amino acid carrier protein
EXW55_30670	COG3209	COG3209 Rhs family protein
EXW55_30775	COG2002	toxin-antitoxin pair type II binding
EXW55_30780	COG1923	regulation of RNA biosynthetic process
EXW55_30845	COG1121	(ABC) transporter
EXW55_30865	COG1136	(ABC) transporter
EXW55_30870	COG0577	efflux transmembrane transporter activity
EXW55_30955	COG5002	protein histidine kinase activity
EXW55_30960	COG0745	RESPONSE REGULATOR receiver
EXW55_31015	COG0697	spore germination
EXW55_31155	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW55_31180	COG0741	lytic transglycosylase activity
EXW55_31180	COG0791	NLP P60 protein
EXW55_31185	COG5644	endopeptidase inhibitor activity
EXW55_31195	COG0433	COG0433 Predicted ATPase
EXW55_31295	COG0457	Tetratricopeptide repeat
EXW55_31305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW55_31310	COG0785	Cytochrome C biogenesis protein
EXW55_31320	COG0582	viral genome integration into host DNA
EXW55_31515	COG0791	NLP P60 protein
EXW55_31515	COG0741	lytic transglycosylase activity
EXW55_31610	COG0551	DNA topoisomerase type I activity
EXW55_31610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW55_31635	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EXW55_31650	COG4974	Belongs to the 'phage' integrase family
EXW55_31690	COG4974	Belongs to the 'phage' integrase family
EXW55_31715	COG0277	FAD linked oxidase domain protein
EXW55_31720	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW55_31730	COG2226	methyltransferase
EXW55_31775	COG0457	Tetratricopeptide repeat
EXW55_31785	COG4166	transmembrane transport
EXW55_31820	COG1192	Involved in chromosome partitioning
EXW55_31835	COG0457	Tetratricopeptide repeat
EXW55_31960	COG0791	NLP P60 protein
EXW55_31960	COG0741	lytic transglycosylase activity
EXW55_32040	COG2002	toxin-antitoxin pair type II binding
EXW55_32045	COG1923	regulation of RNA biosynthetic process
EXW55_32090	COG0823	Involved in the tonB-independent uptake of proteins
EXW55_32130	COG0659	secondary active sulfate transmembrane transporter activity
EXW55_32135	COG0288	reversible hydration of carbon dioxide
EXW55_32295	COG1396	sequence-specific DNA binding