locus-tag	class	description
EXW56_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW56_00010	COG0592	DNA-directed DNA polymerase activity
EXW56_00015	COG2501	S4 domain
EXW56_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW56_00025	COG0187	DNA topoisomerase II activity
EXW56_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW56_00065	COG0516	GMP reductase activity
EXW56_00065	COG0517	IMP dehydrogenase activity
EXW56_00070	COG1686	Belongs to the peptidase S11 family
EXW56_00100	COG1428	Deoxynucleoside kinase
EXW56_00105	COG1428	Deoxynucleoside kinase
EXW56_00110	COG1335	isochorismatase
EXW56_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW56_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW56_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW56_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW56_00180	COG1982	Orn Lys Arg decarboxylase major
EXW56_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW56_00190	COG0470	DNA polymerase III
EXW56_00195	COG1774	PSP1 C-terminal conserved region
EXW56_00200	COG4467	Involved in initiation control of chromosome replication
EXW56_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW56_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW56_00220	COG2002	toxin-antitoxin pair type II binding
EXW56_00230	COG0084	hydrolase, TatD family'
EXW56_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW56_00250	COG4466	Protein conserved in bacteria
EXW56_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW56_00270	COG0251	oxidation-reduction process
EXW56_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW56_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW56_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW56_00305	COG2002	toxin-antitoxin pair type II binding
EXW56_00310	COG2244	polysaccharide biosynthetic process
EXW56_00315	COG3956	TIGRFAM MazG family protein
EXW56_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW56_00340	COG1098	S1 RNA binding domain
EXW56_00355	COG2208	phosphoserine phosphatase activity
EXW56_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW56_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW56_00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW56_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW56_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW56_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW56_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW56_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW56_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW56_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW56_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW56_00420	COG1396	sequence-specific DNA binding
EXW56_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW56_00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW56_00515	COG3880	PFAM UvrB UvrC protein
EXW56_00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW56_00525	COG0542	response to heat
EXW56_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW56_00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW56_00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW56_00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW56_00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW56_00560	COG1045	serine acetyltransferase
EXW56_00565	COG0215	cysteine-tRNA ligase activity
EXW56_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW56_00580	COG3688	RNA-binding protein containing a PIN domain
EXW56_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW56_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW56_00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW56_00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW56_00610	COG0081	regulation of translation
EXW56_00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW56_00620	COG0222	ribosome binding
EXW56_00625	COG2813	Specifically methylates the guanine in position
EXW56_00630	COG0085	RNA polymerase activity
EXW56_00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW56_00640	COG1358	cellular component organization or biogenesis
EXW56_00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW56_00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW56_00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW56_00665	COG0051	transcription antitermination factor activity, RNA binding
EXW56_00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW56_00675	COG0088	Forms part of the polypeptide exit tunnel
EXW56_00680	COG0089	rRNA binding
EXW56_00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW56_00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW56_00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW56_00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW56_00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW56_00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW56_00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW56_00760	COG1841	ribosomal large subunit assembly
EXW56_00765	COG0200	Binds to the 23S rRNA
EXW56_00770	COG0201	protein transport
EXW56_00775	COG0563	adenylate kinase activity
EXW56_00780	COG0024	Methionine aminopeptidase
EXW56_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW56_00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW56_00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW56_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW56_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW56_00855	COG0489	protein tyrosine kinase activity
EXW56_00865	COG2194	sulfuric ester hydrolase activity
EXW56_00870	COG0726	polysaccharide deacetylase
EXW56_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW56_00955	COG4856	YbbR-like protein
EXW56_00990	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_00995	COG2011	ABC-type metal ion transport system permease component
EXW56_01005	COG1464	Belongs to the NlpA lipoprotein family
EXW56_01015	COG0277	FAD linked oxidase domain protein
EXW56_01020	COG2271	Major facilitator Superfamily
EXW56_01030	COG2814	Major facilitator Superfamily
EXW56_01050	COG0601	transmembrane transport
EXW56_01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW56_01060	COG0444	Belongs to the ABC transporter superfamily
EXW56_01065	COG4608	Belongs to the ABC transporter superfamily
EXW56_01070	COG4166	transmembrane transport
EXW56_01080	COG2207	Transcriptional regulator
EXW56_01095	COG4166	transmembrane transport
EXW56_01100	COG4166	transmembrane transport
EXW56_01105	COG0656	L-ascorbic acid biosynthetic process
EXW56_01110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW56_01120	COG4149	molybdate abc transporter
EXW56_01125	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW56_01130	COG1910	domain protein
EXW56_01140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW56_01170	COG0697	spore germination
EXW56_01185	COG0204	Acyl-transferase
EXW56_01195	COG1609	Transcriptional regulator
EXW56_01205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW56_01225	COG5298	Protein conserved in bacteria
EXW56_01250	COG0488	(ABC) transporter
EXW56_01255	COG4585	Histidine kinase
EXW56_01260	COG2197	response regulator
EXW56_01265	COG1131	(ABC) transporter
EXW56_01270	COG0842	Transport permease protein
EXW56_01270	COG1511	domain protein
EXW56_01275	COG0842	Transport permease protein
EXW56_01285	COG0747	negative chemotaxis
EXW56_01295	COG0601	transmembrane transport
EXW56_01300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW56_01305	COG0444	Belongs to the ABC transporter superfamily
EXW56_01310	COG4608	Belongs to the ABC transporter superfamily
EXW56_01315	COG0561	phosphatase activity
EXW56_01345	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW56_01350	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW56_01360	COG0531	amino acid
EXW56_01365	COG2814	Major facilitator Superfamily
EXW56_01375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW56_01385	COG4294	response to UV
EXW56_01390	COG0705	Rhomboid family
EXW56_01395	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW56_01400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW56_01405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW56_01410	COG0864	Transcriptional regulator
EXW56_01415	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW56_01420	COG2183	response to ionizing radiation
EXW56_01520	COG0802	atpase or kinase
EXW56_01525	COG1214	PFAM Peptidase M22, glycoprotease
EXW56_01530	COG0456	acetyltransferase
EXW56_01540	COG0488	(ABC) transporter
EXW56_01545	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW56_01555	COG1266	CAAX protease self-immunity
EXW56_01560	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW56_01565	COG0459	protein refolding
EXW56_01595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW56_01595	COG0519	Catalyzes the synthesis of GMP from XMP
EXW56_01600	COG2252	PERMEase
EXW56_01610	COG5002	protein histidine kinase activity
EXW56_01630	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW56_01680	COG4187	Peptidase family M20/M25/M40
EXW56_01715	COG2205	protein histidine kinase activity
EXW56_01745	COG0697	spore germination
EXW56_01770	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW56_01775	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW56_01780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW56_01790	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW56_01795	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW56_01805	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW56_01815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW56_01820	COG0138	bifunctional purine biosynthesis protein purh
EXW56_01825	COG0151	Belongs to the GarS family
EXW56_01845	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW56_01850	COG0210	DNA helicase
EXW56_01855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW56_01860	COG4851	CamS sex pheromone cAM373 precursor
EXW56_01870	COG1012	belongs to the aldehyde dehydrogenase family
EXW56_01875	COG1335	isochorismatase
EXW56_01885	COG2011	ABC-type metal ion transport system permease component
EXW56_01890	COG1464	Belongs to the NlpA lipoprotein family
EXW56_01905	COG0003	Pfam Anion-transporting ATPase
EXW56_01910	COG1846	Transcriptional regulator
EXW56_01915	COG4682	membrane
EXW56_01930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW56_01935	COG1597	lipid kinase activity
EXW56_01950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW56_01965	COG1012	belongs to the aldehyde dehydrogenase family
EXW56_01970	COG2076	Multidrug Resistance protein
EXW56_01980	COG2309	aminopeptidase activity
EXW56_01995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW56_02005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW56_02010	COG5002	protein histidine kinase activity
EXW56_02015	COG4807	Protein conserved in bacteria
EXW56_02040	COG1757	Na H antiporter
EXW56_02045	COG1473	amidohydrolase
EXW56_02060	COG0450	alkyl hydroperoxide reductase
EXW56_02070	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW56_02080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW56_02085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW56_02090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW56_02100	COG0492	ferredoxin-NADP+ reductase activity
EXW56_02115	COG0166	Belongs to the GPI family
EXW56_02140	COG5002	protein histidine kinase activity
EXW56_02155	COG3541	Predicted nucleotidyltransferase
EXW56_02160	COG0723	plastoquinol--plastocyanin reductase activity
EXW56_02160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW56_02170	COG0765	amino acid transport
EXW56_02175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW56_02180	COG1126	abc transporter atp-binding protein
EXW56_02185	COG0840	transmembrane signaling receptor activity
EXW56_02190	COG0277	FAD linked oxidase domain protein
EXW56_02195	COG0366	Alpha amylase catalytic
EXW56_02200	COG1263	PTS System
EXW56_02200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW56_02200	COG2190	(PTS) system
EXW56_02220	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW56_02225	COG0352	thiamine-phosphate diphosphorylase activity
EXW56_02230	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW56_02250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW56_02255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW56_02260	COG1116	anion transmembrane transporter activity
EXW56_02265	COG0488	(ABC) transporter
EXW56_02310	COG2270	Major facilitator Superfamily
EXW56_02340	COG2310	stress, protein
EXW56_02345	COG2310	stress, protein
EXW56_02350	COG2310	stress, protein
EXW56_02355	COG0861	Integral membrane protein TerC family
EXW56_02365	COG3853	Toxic anion resistance protein (TelA)
EXW56_02375	COG4840	Belongs to the UPF0435 family
EXW56_02380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW56_02390	COG1295	ribonuclease BN
EXW56_02395	COG2217	Heavy metal translocating P-type atpase
EXW56_02400	COG0697	spore germination
EXW56_02420	COG0586	Pfam SNARE associated Golgi protein
EXW56_02435	COG3871	stress protein (general stress protein 26)
EXW56_02440	COG0387	Pfam Sodium calcium exchanger
EXW56_02450	COG0535	radical SAM domain protein
EXW56_02470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW56_02490	COG3829	transcription factor binding
EXW56_02500	COG0833	amino acid
EXW56_02510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW56_02535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW56_02535	COG1263	PTS System
EXW56_02540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW56_02560	COG1215	transferase activity, transferring glycosyl groups
EXW56_02570	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW56_02570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW56_02575	COG0463	Glycosyl transferase, family 2
EXW56_02590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW56_02595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW56_02610	COG1228	amidohydrolase
EXW56_02615	COG1090	epimerase
EXW56_02620	COG2137	regulation of response to DNA damage stimulus
EXW56_02645	COG1988	membrane-bound metal-dependent
EXW56_02650	COG1194	a g-specific adenine glycosylase
EXW56_02665	COG3557	Belongs to the UPF0374 family
EXW56_02670	COG1132	(ABC) transporter
EXW56_02675	COG4129	membrane
EXW56_02680	COG0070	glutamate synthase
EXW56_02680	COG0067	glutamate synthase
EXW56_02680	COG0069	glutamate synthase activity
EXW56_02685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW56_02690	COG4555	ABC transporter
EXW56_02710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW56_02715	COG0735	belongs to the Fur family
EXW56_02830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW56_02835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW56_02855	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW56_02865	COG2766	serine protein kinase
EXW56_02870	COG2718	Belongs to the UPF0229 family
EXW56_02885	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW56_02890	COG2268	Band 7 protein
EXW56_02895	COG3290	protein histidine kinase activity
EXW56_02900	COG4565	transcriptional regulatory protein
EXW56_02905	COG2851	Citrate transporter
EXW56_02930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW56_02935	COG0745	RESPONSE REGULATOR receiver
EXW56_02940	COG5002	protein histidine kinase activity
EXW56_02950	COG4990	cell redox homeostasis
EXW56_02955	COG3290	protein histidine kinase activity
EXW56_02960	COG4565	transcriptional regulatory protein
EXW56_02965	COG3493	citrate carrier protein
EXW56_02970	COG0281	malic enzyme
EXW56_02980	COG0697	spore germination
EXW56_02985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW56_02995	COG5002	protein histidine kinase activity
EXW56_03000	COG0745	RESPONSE REGULATOR receiver
EXW56_03005	COG0456	acetyltransferase
EXW56_03010	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW56_03015	COG3383	formate dehydrogenase (NAD+) activity
EXW56_03020	COG2427	Protein of unknown function (DUF1641)
EXW56_03035	COG0531	amino acid
EXW56_03045	COG0640	Transcriptional regulator
EXW56_03050	COG2217	Heavy metal translocating P-type atpase
EXW56_03055	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW56_03065	COG3227	Zinc metalloprotease (Elastase)
EXW56_03085	COG2720	vancomycin resistance protein
EXW56_03090	COG1316	TRANSCRIPTIONal
EXW56_03095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW56_03100	COG0346	lactoylglutathione lyase activity
EXW56_03105	COG1253	flavin adenine dinucleotide binding
EXW56_03110	COG1027	Aspartate ammonia-lyase
EXW56_03115	COG1620	l-lactate permease
EXW56_03120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW56_03140	COG3104	oligopeptide transport
EXW56_03145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW56_03150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW56_03155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW56_03170	COG0156	8-amino-7-oxononanoate synthase activity
EXW56_03175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW56_03180	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EXW56_03190	COG4548	von Willebrand factor, type A
EXW56_03195	COG0714	Associated with various cellular activities
EXW56_03220	COG0531	amino acid
EXW56_03225	COG2188	Transcriptional regulator
EXW56_03230	COG1263	PTS System
EXW56_03230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW56_03235	COG0366	Alpha amylase catalytic
EXW56_03255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW56_03260	COG1115	amino acid carrier protein
EXW56_03265	COG1126	abc transporter atp-binding protein
EXW56_03270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW56_03275	COG0765	amino acid transport
EXW56_03280	COG0765	amino acid transport
EXW56_03285	COG0833	amino acid
EXW56_03310	COG2378	regulation of single-species biofilm formation
EXW56_03315	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW56_03320	COG5002	protein histidine kinase activity
EXW56_03335	COG0659	secondary active sulfate transmembrane transporter activity
EXW56_03350	COG2271	Major facilitator Superfamily
EXW56_03355	COG1846	Transcriptional regulator
EXW56_03360	COG0477	Major facilitator Superfamily
EXW56_03365	COG1609	Transcriptional regulator
EXW56_03370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW56_03375	COG1869	D-ribose catabolic process
EXW56_03385	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW56_03390	COG1879	ABC-type sugar transport system periplasmic component
EXW56_03420	COG1063	alcohol dehydrogenase
EXW56_03470	COG0840	transmembrane signaling receptor activity
EXW56_03475	COG3584	3D domain protein
EXW56_03475	COG3583	domain protein
EXW56_03480	COG1476	TRANSCRIPTIONal
EXW56_03500	COG3104	oligopeptide transport
EXW56_03505	COG1114	Component of the transport system for branched-chain amino acids
EXW56_03520	COG1113	amino acid transport
EXW56_03525	COG2252	PERMEase
EXW56_03540	COG2153	protein acetylation
EXW56_03550	COG0569	domain protein
EXW56_03550	COG0475	glutathione-regulated potassium exporter activity
EXW56_03560	COG1845	cytochrome c oxidase, subunit III
EXW56_03565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW56_03570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EXW56_03575	COG0833	amino acid
EXW56_03580	COG4990	cell redox homeostasis
EXW56_03595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW56_03600	COG0697	spore germination
EXW56_03605	COG0531	amino acid
EXW56_03615	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW56_03620	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW56_03630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW56_03635	COG0573	inorganic phosphate transmembrane transporter activity
EXW56_03640	COG0581	inorganic phosphate transmembrane transporter activity
EXW56_03650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW56_03695	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW56_03775	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW56_03790	COG4991	sh3 domain protein
EXW56_03790	COG3103	Sh3 type 3 domain protein
EXW56_03790	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW56_03795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW56_03800	COG1116	anion transmembrane transporter activity
EXW56_03805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW56_03810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW56_03815	COG0352	thiamine-phosphate diphosphorylase activity
EXW56_03820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW56_03825	COG2104	thiamine diphosphate biosynthetic process
EXW56_03830	COG2022	thiamine diphosphate biosynthetic process
EXW56_03835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW56_03840	COG0351	phosphomethylpyrimidine kinase
EXW56_03870	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW56_03875	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW56_03880	COG2205	protein histidine kinase activity
EXW56_03915	COG1136	(ABC) transporter
EXW56_03925	COG2252	PERMEase
EXW56_03930	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_03990	COG0778	Nitroreductase
EXW56_03995	COG2719	SpoVR family
EXW56_04020	COG1937	Protein conserved in bacteria
EXW56_04025	COG0425	Belongs to the sulfur carrier protein TusA family
EXW56_04025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW56_04030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW56_04030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW56_04035	COG0425	Belongs to the sulfur carrier protein TusA family
EXW56_04040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW56_04045	COG2210	Belongs to the sulfur carrier protein TusA family
EXW56_04050	COG0730	response to heat
EXW56_04060	COG1316	TRANSCRIPTIONal
EXW56_04065	COG0604	alcohol dehydrogenase
EXW56_04070	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW56_04095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW56_04095	COG3711	transcriptional antiterminator
EXW56_04100	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW56_04105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW56_04130	COG1388	LysM domain
EXW56_04130	COG3584	3D domain protein
EXW56_04135	COG0577	efflux transmembrane transporter activity
EXW56_04140	COG1136	(ABC) transporter
EXW56_04150	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW56_04165	COG1114	Component of the transport system for branched-chain amino acids
EXW56_04170	COG3546	catalase activity
EXW56_04215	COG0586	Pfam SNARE associated Golgi protein
EXW56_04245	COG0531	amino acid
EXW56_04250	COG0475	glutathione-regulated potassium exporter activity
EXW56_04260	COG1737	Transcriptional regulator
EXW56_04270	COG1263	PTS System
EXW56_04270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW56_04280	COG2259	Doxx family
EXW56_04305	COG1522	sequence-specific DNA binding
EXW56_04315	COG0300	oxidoreductase activity
EXW56_04330	COG2076	Multidrug Resistance protein
EXW56_04335	COG1309	transcriptional regulator
EXW56_04345	COG2814	Major facilitator Superfamily
EXW56_04350	COG1733	regulation of RNA biosynthetic process
EXW56_04360	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW56_04370	COG4533	DNA binding
EXW56_04375	COG2211	Major facilitator Superfamily
EXW56_04385	COG4473	ABC transporter
EXW56_04390	COG0531	amino acid
EXW56_04395	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EXW56_04400	COG1012	belongs to the aldehyde dehydrogenase family
EXW56_04415	COG1132	(ABC) transporter
EXW56_04420	COG1132	(ABC) transporter
EXW56_04425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW56_04430	COG0765	amino acid transport
EXW56_04435	COG1126	abc transporter atp-binding protein
EXW56_04450	COG0189	ligase activity
EXW56_04460	COG4399	Belongs to the UPF0754 family
EXW56_04465	COG3679	Belongs to the UPF0342 family
EXW56_04470	COG0463	Glycosyl transferase, family 2
EXW56_04475	COG1216	Glycosyl transferase, family 2
EXW56_04480	COG2094	Belongs to the DNA glycosylase MPG family
EXW56_04485	COG0561	phosphatase activity
EXW56_04490	COG3409	Peptidoglycan-binding domain 1 protein
EXW56_04490	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW56_04495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW56_04510	COG0586	Pfam SNARE associated Golgi protein
EXW56_04520	COG4978	Transcriptional regulator
EXW56_04520	COG0789	Transcriptional regulator
EXW56_04530	COG0659	secondary active sulfate transmembrane transporter activity
EXW56_04535	COG2244	polysaccharide biosynthetic process
EXW56_04555	COG1024	Enoyl-CoA hydratase
EXW56_04575	COG1363	Peptidase, m42
EXW56_04600	COG1113	amino acid transport
EXW56_04605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW56_04625	COG0579	oxidoreductase
EXW56_04630	COG2226	methyltransferase
EXW56_04635	COG3829	transcription factor binding
EXW56_04635	COG3290	protein histidine kinase activity
EXW56_04665	COG1160	GTP binding
EXW56_04675	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW56_04705	COG0601	transmembrane transport
EXW56_04710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW56_04715	COG0444	Belongs to the ABC transporter superfamily
EXW56_04720	COG4608	Belongs to the ABC transporter superfamily
EXW56_04860	COG0514	ATP-dependent DNA helicase (RecQ)
EXW56_04865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW56_04885	COG0305	Participates in initiation and elongation during chromosome replication
EXW56_04920	COG0477	Major facilitator Superfamily
EXW56_04980	COG1183	phosphatidylcholine synthase activity
EXW56_04985	COG0586	Pfam SNARE associated Golgi protein
EXW56_05000	COG2814	Major facilitator Superfamily
EXW56_05005	COG0640	Transcriptional regulator
EXW56_05035	COG2376	Dihydroxyacetone kinase
EXW56_05055	COG2376	Dihydroxyacetone kinase
EXW56_05080	COG2755	lipolytic protein G-D-S-L family
EXW56_05080	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW56_05095	COG1335	isochorismatase
EXW56_05100	COG2373	Large extracellular alpha-helical protein
EXW56_05105	COG0596	Alpha beta hydrolase
EXW56_05135	COG2807	transmembrane transport
EXW56_05140	COG2186	Transcriptional regulator
EXW56_05160	COG4585	Histidine kinase
EXW56_05165	COG2197	response regulator
EXW56_05190	COG0420	3'-5' exonuclease activity
EXW56_05195	COG4717	serine-type aminopeptidase activity
EXW56_05200	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW56_05205	COG0346	lactoylglutathione lyase activity
EXW56_05210	COG2267	carboxylic ester hydrolase activity
EXW56_05225	COG3620	sequence-specific DNA binding
EXW56_05230	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW56_05235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW56_05240	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW56_05245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW56_05260	COG1309	transcriptional regulator
EXW56_05265	COG2814	Major facilitator Superfamily
EXW56_05270	COG3973	AAA domain
EXW56_05305	COG0464	growth
EXW56_05335	COG0537	adenosine 5'-monophosphoramidase activity
EXW56_05340	COG1131	(ABC) transporter
EXW56_05345	COG4473	ABC transporter
EXW56_05370	COG4978	Transcriptional regulator
EXW56_05370	COG0789	Transcriptional regulator
EXW56_05395	COG0247	lactate metabolic process
EXW56_05400	COG1139	Iron-sulfur cluster binding protein
EXW56_05405	COG1556	Lactate utilization protein
EXW56_05420	COG3402	PFAM membrane-flanked domain
EXW56_05425	COG3428	Bacterial PH domain
EXW56_05450	COG3402	PFAM membrane-flanked domain
EXW56_05455	COG3428	Bacterial PH domain
EXW56_05460	COG2329	Antibiotic biosynthesis monooxygenase
EXW56_05465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW56_05475	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW56_05480	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW56_05515	COG1309	transcriptional regulator
EXW56_05520	COG1511	domain protein
EXW56_05525	COG0438	transferase activity, transferring glycosyl groups
EXW56_05525	COG1216	Glycosyl transferase, family 2
EXW56_05565	COG2378	regulation of single-species biofilm formation
EXW56_05570	COG1609	Transcriptional regulator
EXW56_05580	COG1234	tRNA 3'-trailer cleavage
EXW56_05585	COG0095	Lipoate-protein ligase
EXW56_05595	COG0318	PFAM AMP-dependent synthetase and ligase
EXW56_05605	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW56_05610	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW56_05615	COG4208	sulfate ABC transporter
EXW56_05725	COG1408	metallophosphoesterase
EXW56_05730	COG1078	dGTPase activity
EXW56_05745	COG1595	DNA-templated transcription, initiation
EXW56_05750	COG2207	Transcriptional regulator
EXW56_05750	COG3708	Transcriptional regulator
EXW56_05765	COG2205	protein histidine kinase activity
EXW56_05770	COG0745	RESPONSE REGULATOR receiver
EXW56_05795	COG0501	Belongs to the peptidase M48B family
EXW56_05800	COG0697	spore germination
EXW56_05815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW56_05820	COG2224	Isocitrate lyase
EXW56_05830	COG1278	Cold shock
EXW56_05840	COG4903	ComK protein
EXW56_05845	COG0398	Pfam SNARE associated Golgi protein
EXW56_05855	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW56_05860	COG1074	ATP-dependent DNA helicase activity
EXW56_05915	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW56_05940	COG0367	asparagine synthase
EXW56_05955	COG0753	catalase activity
EXW56_05960	COG0004	ammonium transporteR
EXW56_05980	COG2996	Protein conserved in bacteria
EXW56_05985	COG3209	COG3209 Rhs family protein
EXW56_06050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW56_06060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW56_06075	COG0561	phosphatase activity
EXW56_06095	COG2267	carboxylic ester hydrolase activity
EXW56_06110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW56_06115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW56_06120	COG5504	Zn-dependent protease
EXW56_06140	COG0180	Tryptophanyl-tRNA synthetase
EXW56_06155	COG4166	transmembrane transport
EXW56_06160	COG0601	transmembrane transport
EXW56_06165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW56_06170	COG0444	Belongs to the ABC transporter superfamily
EXW56_06175	COG4608	Belongs to the ABC transporter superfamily
EXW56_06180	COG0534	Mate efflux family protein
EXW56_06185	COG4166	transmembrane transport
EXW56_06200	COG0861	Integral membrane protein TerC family
EXW56_06205	COG4862	establishment of competence for transformation
EXW56_06210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW56_06220	COG1164	Oligoendopeptidase f
EXW56_06230	COG2346	COG2346, Truncated hemoglobins
EXW56_06235	COG4116	CYTH
EXW56_06245	COG2357	RelA SpoT domain protein
EXW56_06255	COG0564	pseudouridine synthase activity
EXW56_06265	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW56_06270	COG0772	Belongs to the SEDS family
EXW56_06280	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW56_06295	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW56_06340	COG2153	protein acetylation
EXW56_06345	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW56_06350	COG2382	esterase
EXW56_06375	COG5492	domain, Protein
EXW56_06380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW56_06395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW56_06395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW56_06400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW56_06405	COG0134	indole-3-glycerol-phosphate synthase activity
EXW56_06410	COG0135	phosphoribosylanthranilate isomerase activity
EXW56_06415	COG0133	tryptophan synthase activity
EXW56_06420	COG0159	tryptophan synthase activity
EXW56_06430	COG1620	l-lactate permease
EXW56_06440	COG5634	Uncharacterized conserved protein (DUF2278)
EXW56_06475	COG2226	methyltransferase
EXW56_06495	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW56_06500	COG0567	Dehydrogenase, E1 component
EXW56_06505	COG1476	TRANSCRIPTIONal
EXW56_06550	COG1686	Belongs to the peptidase S11 family
EXW56_06555	COG0681	Belongs to the peptidase S26 family
EXW56_06590	COG1012	belongs to the aldehyde dehydrogenase family
EXW56_06600	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW56_06605	COG1177	transmembrane transport
EXW56_06610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW56_06620	COG2409	Drug exporters of the RND superfamily
EXW56_06630	COG0564	pseudouridine synthase activity
EXW56_06640	COG2340	Cysteine-rich secretory protein family
EXW56_06645	COG0247	lactate metabolic process
EXW56_06650	COG0277	FAD linked oxidase domain protein
EXW56_06655	COG3835	regulator
EXW56_06665	COG0745	RESPONSE REGULATOR receiver
EXW56_06670	COG3850	Histidine kinase
EXW56_06670	COG5002	protein histidine kinase activity
EXW56_06675	COG2186	Transcriptional regulator
EXW56_06690	COG1556	Lactate utilization protein
EXW56_06695	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW56_06710	COG0583	DNA-binding transcription factor activity
EXW56_06720	COG0825	malonyl-CoA metabolic process
EXW56_06740	COG2116	formate transmembrane transporter activity
EXW56_06745	COG0861	Integral membrane protein TerC family
EXW56_06750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW56_06760	COG2030	dehydratase
EXW56_06780	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_06785	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW56_06795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW56_06810	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW56_06815	COG3842	ATPase activity
EXW56_06825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW56_06830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW56_06840	COG1349	DNA-binding transcription factor activity
EXW56_06850	COG0235	Class ii aldolase
EXW56_06860	COG2861	carbohydrate metabolic process
EXW56_06870	COG3852	Histidine kinase
EXW56_06875	COG1846	Transcriptional regulator
EXW56_06885	COG2318	DinB family
EXW56_06890	COG5002	protein histidine kinase activity
EXW56_06900	COG0720	synthase
EXW56_06915	COG4873	Protein conserved in bacteria
EXW56_06925	COG0456	acetyltransferase
EXW56_06945	COG1780	Probably involved in ribonucleotide reductase function
EXW56_06960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW56_06965	COG0531	amino acid
EXW56_06985	COG2204	response regulator
EXW56_06990	COG1012	belongs to the aldehyde dehydrogenase family
EXW56_07000	COG1725	Transcriptional regulator
EXW56_07005	COG1131	(ABC) transporter
EXW56_07015	COG1131	(ABC) transporter
EXW56_07020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW56_07025	COG1266	CAAX protease self-immunity
EXW56_07035	COG1522	sequence-specific DNA binding
EXW56_07045	COG1335	isochorismatase
EXW56_07055	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW56_07060	COG2070	2-Nitropropane dioxygenase
EXW56_07065	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW56_07070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW56_07075	COG1696	Membrane protein involved in D-alanine export
EXW56_07095	COG0716	FMN binding
EXW56_07105	COG3173	Aminoglycoside phosphotransferase
EXW56_07120	COG0534	Mate efflux family protein
EXW56_07145	COG1846	Transcriptional regulator
EXW56_07160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW56_07170	COG3874	Sporulation protein YtfJ
EXW56_07190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW56_07195	COG0028	Belongs to the TPP enzyme family
EXW56_07200	COG0440	acetolactate synthase activity
EXW56_07210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW56_07230	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW56_07235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW56_07245	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW56_07250	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW56_07255	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW56_07260	COG0107	imidazoleglycerol-phosphate synthase activity
EXW56_07275	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW56_07290	COG1183	phosphatidylcholine synthase activity
EXW56_07295	COG1368	sulfuric ester hydrolase activity
EXW56_07305	COG0019	diaminopimelate decarboxylase activity
EXW56_07320	COG2046	Belongs to the sulfate adenylyltransferase family
EXW56_07325	COG0529	Catalyzes the synthesis of activated sulfate
EXW56_07330	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW56_07350	COG1648	precorrin-2 dehydrogenase activity
EXW56_07355	COG0733	neurotransmitter:sodium symporter activity
EXW56_07375	COG1757	Na H antiporter
EXW56_07390	COG4758	membrane
EXW56_07395	COG4585	Histidine kinase
EXW56_07400	COG2197	response regulator
EXW56_07410	COG1114	Component of the transport system for branched-chain amino acids
EXW56_07465	COG0730	response to heat
EXW56_07470	COG0306	phosphate transporter
EXW56_07475	COG1392	Phosphate transport regulator
EXW56_07480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW56_07495	COG3852	Histidine kinase
EXW56_07500	COG1801	Protein of unknown function DUF72
EXW56_07510	COG0582	viral genome integration into host DNA
EXW56_07515	COG5002	protein histidine kinase activity
EXW56_07530	COG0392	lysyltransferase activity
EXW56_07530	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW56_07545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW56_07550	COG1686	Belongs to the peptidase S11 family
EXW56_07555	COG2715	membrane protein required for spore maturation
EXW56_07560	COG0700	Nucleoside recognition
EXW56_07565	COG1187	pseudouridine synthase activity
EXW56_07575	COG1333	cytochrome c biogenesis protein
EXW56_07580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW56_07585	COG0745	RESPONSE REGULATOR receiver
EXW56_07590	COG5002	protein histidine kinase activity
EXW56_07595	COG2096	Adenosyltransferase
EXW56_07600	COG4942	peptidase
EXW56_07610	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW56_07615	COG1141	Ferredoxin
EXW56_07625	COG4955	Helix-turn-helix domain
EXW56_07630	COG0514	ATP-dependent DNA helicase (RecQ)
EXW56_07635	COG1266	CAAX protease self-immunity
EXW56_07645	COG1408	metallophosphoesterase
EXW56_07660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW56_07675	COG0492	ferredoxin-NADP+ reductase activity
EXW56_07680	COG0252	asparaginase activity
EXW56_07690	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW56_07700	COG1304	FMN binding
EXW56_07735	COG1160	GTP binding
EXW56_07760	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW56_07775	COG0142	geranyltranstransferase activity
EXW56_07780	COG2226	methyltransferase
EXW56_07785	COG0142	geranyltranstransferase activity
EXW56_07800	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW56_07810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW56_07815	COG0457	Tetratricopeptide repeat
EXW56_07820	COG5582	Belongs to the UPF0302 family
EXW56_07835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW56_07840	COG2010	Cytochrome c
EXW56_07840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW56_07850	COG4347	Protein of unknown function (DUF1405)
EXW56_07865	COG2738	Putative neutral zinc metallopeptidase
EXW56_07875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW56_07885	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW56_07890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW56_07895	COG1803	Methylglyoxal synthase
EXW56_07900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW56_07905	COG0438	transferase activity, transferring glycosyl groups
EXW56_07910	COG0617	tRNA 3'-terminal CCA addition
EXW56_07920	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW56_07925	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW56_07935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW56_07935	COG1199	ATP-dependent helicase activity
EXW56_07955	COG3935	DnaD domain protein
EXW56_07960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW56_07970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW56_07970	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW56_07975	COG3331	DNA recombination
EXW56_08010	COG4474	Belongs to the UPF0398 family
EXW56_08015	COG3599	regulation of cell shape
EXW56_08025	COG0116	Belongs to the methyltransferase superfamily
EXW56_08035	COG1199	ATP-dependent helicase activity
EXW56_08040	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW56_08050	COG0024	Methionine aminopeptidase
EXW56_08060	COG2233	PERMEase
EXW56_08065	COG2311	Membrane
EXW56_08070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW56_08080	COG0456	acetyltransferase
EXW56_08090	COG2897	thiosulfate sulfurtransferase activity
EXW56_08130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW56_08150	COG0454	-acetyltransferase
EXW56_08170	COG0328	RNA-DNA hybrid ribonuclease activity
EXW56_08205	COG3403	YqcI/YcgG family
EXW56_08210	COG1280	lysine exporter protein (LysE YggA)
EXW56_08225	COG3162	membrane
EXW56_08230	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW56_08235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW56_08245	COG0475	glutathione-regulated potassium exporter activity
EXW56_08250	COG0789	Transcriptional regulator
EXW56_08250	COG4978	Transcriptional regulator
EXW56_08255	COG0534	Mate efflux family protein
EXW56_08260	COG2323	membrane
EXW56_08265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW56_08285	COG1609	Transcriptional regulator
EXW56_08295	COG1175	transmembrane transport
EXW56_08300	COG0395	ABC-type sugar transport system, permease component
EXW56_08305	COG5578	integral membrane protein
EXW56_08315	COG1486	melibiose metabolic process
EXW56_08330	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EXW56_08335	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW56_08340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW56_08380	COG1923	regulation of RNA biosynthetic process
EXW56_08390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW56_08395	COG1360	Flagellar Motor Protein
EXW56_08400	COG2201	protein-glutamate methylesterase activity
EXW56_08405	COG2198	Histidine kinase
EXW56_08405	COG0643	Histidine kinase
EXW56_08410	COG1776	CheC inhibitor of MCP methylation
EXW56_08410	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW56_08425	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW56_08445	COG1256	bacterial-type flagellum assembly
EXW56_08450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW56_08470	COG1815	bacterial-type flagellum-dependent cell motility
EXW56_08475	COG1558	bacterial-type flagellum-dependent cell motility
EXW56_08485	COG1766	The M ring may be actively involved in energy transduction
EXW56_08490	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW56_08500	COG1157	protein secretion by the type III secretion system
EXW56_08520	COG1749	Flagellar hook protein flgE
EXW56_08535	COG0784	Response regulator, receiver
EXW56_08535	COG0835	chemotaxis
EXW56_08545	COG0861	Integral membrane protein TerC family
EXW56_08555	COG3383	formate dehydrogenase (NAD+) activity
EXW56_08560	COG2427	Protein of unknown function (DUF1641)
EXW56_08565	COG5609	conserved protein (DUF2294)
EXW56_08570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW56_08580	COG2116	formate transmembrane transporter activity
EXW56_08585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW56_08590	COG0303	'Molybdopterin
EXW56_08595	COG0314	molybdopterin synthase activity
EXW56_08610	COG0489	protein tyrosine kinase activity
EXW56_08615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW56_08615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW56_08620	COG0741	lytic transglycosylase activity
EXW56_08630	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW56_08635	COG1776	CheC inhibitor of MCP methylation
EXW56_08635	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW56_08645	COG1338	Plays a role in the flagellum-specific transport system
EXW56_08650	COG1987	bacterial-type flagellum assembly
EXW56_08660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW56_08665	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW56_08670	COG1419	protein localization to endoplasmic reticulum
EXW56_08675	COG4786	Flagellar basal body rod
EXW56_08710	COG0412	Dienelactone hydrolase
EXW56_08715	COG2329	Antibiotic biosynthesis monooxygenase
EXW56_08730	COG3764	Sortase (surface protein transpeptidase)
EXW56_08735	COG3764	Sortase (surface protein transpeptidase)
EXW56_08760	COG0583	DNA-binding transcription factor activity
EXW56_08765	COG3842	ATPase activity
EXW56_08825	COG1846	Transcriptional regulator
EXW56_08835	COG0367	asparagine synthase
EXW56_08865	COG1757	Na H antiporter
EXW56_08875	COG0277	FAD linked oxidase domain protein
EXW56_08890	COG0534	Mate efflux family protein
EXW56_08895	COG3340	Belongs to the peptidase S51 family
EXW56_08915	COG0785	Cytochrome C biogenesis protein
EXW56_08935	COG3048	D-serine ammonia-lyase activity
EXW56_08940	COG2733	membrane
EXW56_08985	COG1131	(ABC) transporter
EXW56_09005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW56_09015	COG0457	Tetratricopeptide repeat
EXW56_09025	COG3157	Type VI secretion system effector, Hcp
EXW56_09045	COG0528	UMP kinase activity
EXW56_09055	COG1027	Aspartate ammonia-lyase
EXW56_09060	COG0281	malic enzyme
EXW56_09065	COG4191	Histidine kinase
EXW56_09070	COG0784	Response regulator, receiver
EXW56_09075	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW56_09090	COG2502	aspartate--ammonia ligase
EXW56_09130	COG2814	Major facilitator Superfamily
EXW56_09155	COG1695	Transcriptional regulator
EXW56_09170	COG0477	Major facilitator Superfamily
EXW56_09185	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW56_09190	COG2223	nitrite transmembrane transporter activity
EXW56_09195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW56_09210	COG2244	polysaccharide biosynthetic process
EXW56_09215	COG0733	neurotransmitter:sodium symporter activity
EXW56_09225	COG5566	PFAM Mor transcription activator
EXW56_09230	COG2323	membrane
EXW56_09250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW56_09265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW56_09280	COG1811	Na channel or pump
EXW56_09290	COG2814	Major facilitator Superfamily
EXW56_09295	COG3384	dioxygenase
EXW56_09350	COG4166	transmembrane transport
EXW56_09355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW56_09375	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW56_09380	COG1054	Belongs to the UPF0176 family
EXW56_09390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW56_09395	COG0531	amino acid
EXW56_09415	COG1280	lysine exporter protein (LysE YggA)
EXW56_09425	COG2390	Transcriptional regulator
EXW56_09430	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW56_09435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW56_09440	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW56_09455	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW56_09465	COG0006	proline dipeptidase activity
EXW56_09470	COG2132	Multicopper oxidase
EXW56_09485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW56_09495	COG0583	DNA-binding transcription factor activity
EXW56_09515	COG1114	Component of the transport system for branched-chain amino acids
EXW56_09525	COG1276	copper resistance
EXW56_09525	COG2372	response to copper ion
EXW56_09530	COG4549	nuclear export factor GLE1
EXW56_09535	COG0697	spore germination
EXW56_09540	COG0583	DNA-binding transcription factor activity
EXW56_09545	COG1959	2 iron, 2 sulfur cluster binding
EXW56_09550	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW56_09555	COG0778	Nitroreductase
EXW56_09565	COG0628	permease
EXW56_09580	COG1231	oxidoreductase activity
EXW56_09585	COG0523	cobalamin synthesis protein
EXW56_09600	COG2030	dehydratase
EXW56_09605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW56_09620	COG0411	ABC transporter
EXW56_09640	COG0583	DNA-binding transcription factor activity
EXW56_09650	COG1942	4-Oxalocrotonate Tautomerase
EXW56_09665	COG0346	lactoylglutathione lyase activity
EXW56_09675	COG1271	oxidase subunit
EXW56_09680	COG1294	oxidase, subunit
EXW56_09685	COG4988	ABC transporter
EXW56_09690	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW56_09720	COG1686	Belongs to the peptidase S11 family
EXW56_09735	COG0791	NLP P60 protein
EXW56_09735	COG1388	LysM domain
EXW56_09745	COG1132	(ABC) transporter
EXW56_09750	COG0745	RESPONSE REGULATOR receiver
EXW56_09755	COG5002	protein histidine kinase activity
EXW56_09765	COG0300	oxidoreductase activity
EXW56_09795	COG0460	homoserine dehydrogenase
EXW56_09805	COG0083	homoserine kinase activity
EXW56_09820	COG1316	TRANSCRIPTIONal
EXW56_09835	COG1285	pathogenesis
EXW56_09840	COG1247	-acetyltransferase
EXW56_09860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW56_09870	COG1082	Xylose isomerase domain protein TIM barrel
EXW56_09880	COG2814	Major facilitator Superfamily
EXW56_09885	COG1279	arginine transmembrane transporter activity
EXW56_09890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW56_09900	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW56_09935	COG0577	efflux transmembrane transporter activity
EXW56_09940	COG2002	toxin-antitoxin pair type II binding
EXW56_09945	COG1404	Belongs to the peptidase S8 family
EXW56_09955	COG3842	ATPase activity
EXW56_09960	COG2508	Transcriptional regulator
EXW56_09970	COG1653	transport
EXW56_09975	COG1175	transmembrane transport
EXW56_09980	COG0395	ABC-type sugar transport system, permease component
EXW56_09985	COG5426	von Willebrand factor, type A
EXW56_09990	COG1940	carbohydrate kinase activity
EXW56_09995	COG2222	sugar isomerase
EXW56_10005	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW56_10010	COG3684	Belongs to the aldolase LacD family
EXW56_10015	COG0366	Alpha amylase catalytic
EXW56_10020	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW56_10065	COG3949	Membrane
EXW56_10070	COG0783	Belongs to the Dps family
EXW56_10085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW56_10095	COG1231	oxidoreductase activity
EXW56_10100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW56_10105	COG4989	oxidoreductase activity
EXW56_10110	COG0523	cobalamin synthesis protein
EXW56_10115	COG0456	acetyltransferase
EXW56_10120	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW56_10125	COG0702	epimerase
EXW56_10135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW56_10145	COG4166	transmembrane transport
EXW56_10150	COG0346	lactoylglutathione lyase activity
EXW56_10160	COG0406	alpha-ribazole phosphatase activity
EXW56_10170	COG5337	Spore coat protein CotH
EXW56_10175	COG1051	belongs to the nudix hydrolase family
EXW56_10180	COG0586	Pfam SNARE associated Golgi protein
EXW56_10185	COG2244	polysaccharide biosynthetic process
EXW56_10195	COG0701	Predicted permease
EXW56_10200	COG3689	TIGRFAM TIGR03943 family protein
EXW56_10205	COG1607	acyl-coa hydrolase
EXW56_10215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW56_10230	COG0702	epimerase
EXW56_10235	COG2839	Protein conserved in bacteria
EXW56_10240	COG1253	flavin adenine dinucleotide binding
EXW56_10255	COG1114	Component of the transport system for branched-chain amino acids
EXW56_10260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW56_10280	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW56_10290	COG1876	peptidase activity
EXW56_10320	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW56_10330	COG0561	phosphatase activity
EXW56_10340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW56_10360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW56_10365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW56_10390	COG0456	acetyltransferase
EXW56_10425	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW56_10525	COG3874	Sporulation protein YtfJ
EXW56_10550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW56_10570	COG0346	lactoylglutathione lyase activity
EXW56_10580	COG0604	alcohol dehydrogenase
EXW56_10585	COG1595	DNA-templated transcription, initiation
EXW56_10600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW56_10600	COG0426	domain, Protein
EXW56_10610	COG0386	Belongs to the glutathione peroxidase family
EXW56_10615	COG1305	Transglutaminase-like
EXW56_10620	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW56_10625	COG0714	Associated with various cellular activities
EXW56_10635	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW56_10640	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW56_10670	COG2359	stage V sporulation protein S
EXW56_10695	COG4824	toxin secretion phage lysis holin
EXW56_10710	COG0457	Tetratricopeptide repeat
EXW56_10735	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW56_10745	COG1418	mRNA catabolic process
EXW56_10750	COG0488	(ABC) transporter
EXW56_10765	COG0629	single-stranded DNA binding
EXW56_10785	COG1413	lyase activity
EXW56_10800	COG2521	methyltransferase
EXW56_10800	COG2136	Putative SAM-dependent methyltransferase
EXW56_10805	COG0018	arginyl-trna synthetase
EXW56_10860	COG0017	Asparaginyl-tRNA synthetase
EXW56_10865	COG0733	neurotransmitter:sodium symporter activity
EXW56_10895	COG2610	gluconate transmembrane transporter activity
EXW56_10915	COG0456	acetyltransferase
EXW56_10920	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW56_10925	COG1131	(ABC) transporter
EXW56_10930	COG4473	ABC transporter
EXW56_10940	COG0546	phosphoglycolate phosphatase activity
EXW56_10965	COG0671	phosphoesterase, PA-phosphatase related
EXW56_10985	COG0768	penicillin binding
EXW56_11000	COG1272	protein, Hemolysin III
EXW56_11005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW56_11010	COG0805	protein transport
EXW56_11020	COG1307	EDD domain protein, DegV family
EXW56_11025	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW56_11030	COG1999	signal sequence binding
EXW56_11035	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW56_11040	COG0367	asparagine synthase
EXW56_11055	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW56_11060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW56_11065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW56_11085	COG1335	isochorismatase
EXW56_11090	COG1051	belongs to the nudix hydrolase family
EXW56_11095	COG0668	transmembrane transport
EXW56_11100	COG2203	Gaf domain
EXW56_11100	COG4585	Histidine kinase
EXW56_11105	COG2197	response regulator
EXW56_11110	COG1737	Transcriptional regulator
EXW56_11115	COG1064	alcohol dehydrogenase
EXW56_11130	COG1070	Carbohydrate kinase
EXW56_11140	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW56_11160	COG1125	glycine betaine transport
EXW56_11160	COG0517	IMP dehydrogenase activity
EXW56_11165	COG1174	glycine betaine transport
EXW56_11200	COG1253	flavin adenine dinucleotide binding
EXW56_11205	COG1012	belongs to the aldehyde dehydrogenase family
EXW56_11210	COG5506	Protein of unknown function (DUF1694)
EXW56_11225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW56_11230	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW56_11235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW56_11240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW56_11245	COG0456	acetyltransferase
EXW56_11250	COG3829	transcription factor binding
EXW56_11255	COG1509	lysine 2,3-aminomutase activity
EXW56_11265	COG4479	Belongs to the UPF0346 family
EXW56_11290	COG4991	sh3 domain protein
EXW56_11290	COG0515	serine threonine protein kinase
EXW56_11290	COG3064	Membrane
EXW56_11300	COG0671	phosphoesterase, PA-phosphatase related
EXW56_11305	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW56_11310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW56_11330	COG5377	YqaJ viral recombinase family
EXW56_11375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW56_11405	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_11425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW56_11425	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW56_11435	COG2814	Major facilitator Superfamily
EXW56_11440	COG0372	Belongs to the citrate synthase family
EXW56_11445	COG2079	MmgE PrpD family protein
EXW56_11450	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW56_11455	COG1960	acyl-CoA dehydrogenase activity
EXW56_11460	COG2084	Dehydrogenase
EXW56_11465	COG1012	belongs to the aldehyde dehydrogenase family
EXW56_11470	COG1280	lysine exporter protein (LysE YggA)
EXW56_11475	COG1024	Enoyl-CoA hydratase
EXW56_11490	COG0420	3'-5' exonuclease activity
EXW56_11510	COG2223	nitrite transmembrane transporter activity
EXW56_11520	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_11525	COG1169	isochorismate synthase
EXW56_11530	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW56_11535	COG1535	isochorismatase
EXW56_11535	COG3433	isochorismatase activity
EXW56_11540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW56_11545	COG3251	PFAM MbtH domain protein
EXW56_11550	COG2814	Major facilitator Superfamily
EXW56_11565	COG0776	regulation of translation
EXW56_11575	COG2318	DinB family
EXW56_11580	COG1115	amino acid carrier protein
EXW56_11595	COG2329	Antibiotic biosynthesis monooxygenase
EXW56_11610	COG1187	pseudouridine synthase activity
EXW56_11615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW56_11630	COG1136	(ABC) transporter
EXW56_11640	COG0596	Alpha beta hydrolase
EXW56_11660	COG0028	Belongs to the TPP enzyme family
EXW56_11670	COG2226	methyltransferase
EXW56_11690	COG1253	flavin adenine dinucleotide binding
EXW56_11715	COG2267	carboxylic ester hydrolase activity
EXW56_11735	COG1846	Transcriptional regulator
EXW56_11745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW56_11750	COG1309	transcriptional regulator
EXW56_11760	COG0697	spore germination
EXW56_11765	COG0531	amino acid
EXW56_11785	COG1247	-acetyltransferase
EXW56_11825	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW56_11845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW56_11870	COG0561	phosphatase activity
EXW56_11880	COG0583	DNA-binding transcription factor activity
EXW56_11885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW56_11930	COG0583	DNA-binding transcription factor activity
EXW56_11935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW56_11940	COG2258	MOSC domain
EXW56_11955	COG1132	(ABC) transporter
EXW56_11960	COG1132	(ABC) transporter
EXW56_11965	COG0582	viral genome integration into host DNA
EXW56_11975	COG0189	ligase activity
EXW56_11995	COG1396	sequence-specific DNA binding
EXW56_12080	COG0500	methyltransferase
EXW56_12080	COG3615	Tellurite resistance protein tehB
EXW56_12090	COG0693	protein deglycase activity
EXW56_12100	COG0588	phosphoglycerate mutase activity
EXW56_12115	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW56_12150	COG1686	Belongs to the peptidase S11 family
EXW56_12195	COG0768	penicillin binding
EXW56_12200	COG1595	DNA-templated transcription, initiation
EXW56_12210	COG0768	penicillin binding
EXW56_12215	COG0768	penicillin binding
EXW56_12235	COG0697	spore germination
EXW56_12240	COG1408	metallophosphoesterase
EXW56_12250	COG1131	(ABC) transporter
EXW56_12260	COG1309	transcriptional regulator
EXW56_12265	COG1960	acyl-CoA dehydrogenase activity
EXW56_12270	COG0439	Biotin carboxylase
EXW56_12275	COG0511	ligase activity, forming carbon-carbon bonds
EXW56_12280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW56_12285	COG1024	Enoyl-CoA hydratase
EXW56_12290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW56_12295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW56_12360	COG2318	DinB family
EXW56_12365	COG1686	Belongs to the peptidase S11 family
EXW56_12405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW56_12435	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW56_12460	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_12465	COG1733	regulation of RNA biosynthetic process
EXW56_12490	COG1309	transcriptional regulator
EXW56_12520	COG0697	spore germination
EXW56_12525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW56_12560	COG2323	membrane
EXW56_12565	COG2132	Multicopper oxidase
EXW56_12580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW56_12585	COG0697	spore germination
EXW56_12590	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW56_12595	COG0201	protein transport
EXW56_12605	COG0737	Belongs to the 5'-nucleotidase family
EXW56_12615	COG1073	alpha beta
EXW56_12625	COG0577	efflux transmembrane transporter activity
EXW56_12630	COG1136	(ABC) transporter
EXW56_12650	COG5002	protein histidine kinase activity
EXW56_12655	COG0745	RESPONSE REGULATOR receiver
EXW56_12660	COG1011	Hydrolase
EXW56_12685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW56_12690	COG1183	phosphatidylcholine synthase activity
EXW56_12695	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW56_12710	COG1132	(ABC) transporter
EXW56_12725	COG3961	Belongs to the TPP enzyme family
EXW56_12745	COG0322	excinuclease ABC activity
EXW56_12770	COG2318	DinB family
EXW56_12785	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW56_12815	COG0406	alpha-ribazole phosphatase activity
EXW56_12840	COG0592	DNA-directed DNA polymerase activity
EXW56_12855	COG2223	nitrite transmembrane transporter activity
EXW56_12860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW56_12870	COG0494	nUDIX hydrolase
EXW56_12885	COG0697	spore germination
EXW56_12900	COG0584	glycerophosphoryl diester phosphodiesterase
EXW56_12915	COG2814	Major facilitator Superfamily
EXW56_12960	COG0768	penicillin binding
EXW56_12965	COG0671	phosphoesterase, PA-phosphatase related
EXW56_12970	COG0604	alcohol dehydrogenase
EXW56_12975	COG5002	protein histidine kinase activity
EXW56_12980	COG0745	RESPONSE REGULATOR receiver
EXW56_12990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW56_13000	COG2205	protein histidine kinase activity
EXW56_13020	COG4720	Psort location CytoplasmicMembrane, score
EXW56_13025	COG1794	racemase activity, acting on amino acids and derivatives
EXW56_13030	COG1819	glycosyl
EXW56_13040	COG0768	penicillin binding
EXW56_13045	COG5002	protein histidine kinase activity
EXW56_13050	COG0561	phosphatase activity
EXW56_13090	COG2124	cytochrome p450
EXW56_13120	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW56_13130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW56_13135	COG0460	homoserine dehydrogenase
EXW56_13155	COG0577	efflux transmembrane transporter activity
EXW56_13160	COG1136	(ABC) transporter
EXW56_13175	COG0488	(ABC) transporter
EXW56_13180	COG0667	Aldo Keto reductase
EXW56_13185	COG0583	DNA-binding transcription factor activity
EXW56_13190	COG2205	protein histidine kinase activity
EXW56_13195	COG0745	RESPONSE REGULATOR receiver
EXW56_13205	COG3773	Cell wall hydrolase
EXW56_13210	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW56_13220	COG3386	PFAM SMP-30 Gluconolaconase
EXW56_13230	COG0604	alcohol dehydrogenase
EXW56_13260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW56_13275	COG2959	enzyme of heme biosynthesis
EXW56_13300	COG3483	tryptophan 2,3-dioxygenase activity
EXW56_13310	COG3844	kynureninase activity
EXW56_13315	COG1309	transcriptional regulator
EXW56_13330	COG3284	Transcriptional regulator
EXW56_13345	COG1349	DNA-binding transcription factor activity
EXW56_13375	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_13385	COG0494	nUDIX hydrolase
EXW56_13415	COG4176	ABC-type proline glycine betaine transport system permease component
EXW56_13420	COG0517	IMP dehydrogenase activity
EXW56_13420	COG4175	Glycine betaine
EXW56_13445	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW56_13450	COG2153	protein acetylation
EXW56_13455	COG1132	(ABC) transporter
EXW56_13460	COG1819	glycosyl
EXW56_13480	COG2205	protein histidine kinase activity
EXW56_13485	COG2315	Protein conserved in bacteria
EXW56_13540	COG3973	AAA domain
EXW56_13545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW56_13565	COG0514	ATP-dependent DNA helicase (RecQ)
EXW56_13595	COG4637	Psort location Cytoplasmic, score
EXW56_13605	COG1227	inorganic diphosphatase activity
EXW56_13610	COG2318	DinB family
EXW56_13625	COG1162	GTPase activity
EXW56_13630	COG1115	amino acid carrier protein
EXW56_13635	COG1012	belongs to the aldehyde dehydrogenase family
EXW56_13640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW56_13650	COG3938	Belongs to the proline racemase family
EXW56_13655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW56_13695	COG0586	Pfam SNARE associated Golgi protein
EXW56_13710	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW56_13715	COG4166	transmembrane transport
EXW56_13725	COG4948	Mandelate Racemase Muconate Lactonizing
EXW56_13740	COG0667	Aldo Keto reductase
EXW56_13785	COG2936	dipeptidyl-peptidase activity
EXW56_13790	COG5002	protein histidine kinase activity
EXW56_13795	COG0745	RESPONSE REGULATOR receiver
EXW56_13835	COG1164	Oligoendopeptidase f
EXW56_13860	COG1307	EDD domain protein, DegV family
EXW56_13900	COG2814	Major facilitator Superfamily
EXW56_13910	COG1664	Polymer-forming cytoskeletal
EXW56_13915	COG0789	Transcriptional regulator
EXW56_13920	COG4533	DNA binding
EXW56_13925	COG0477	Major facilitator Superfamily
EXW56_13925	COG2814	Major facilitator Superfamily
EXW56_13945	COG2261	transglycosylase associated protein
EXW56_13960	COG2226	methyltransferase
EXW56_14000	COG0436	Aminotransferase
EXW56_14005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW56_14015	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW56_14035	COG1131	(ABC) transporter
EXW56_14075	COG0628	permease
EXW56_14100	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW56_14115	COG0697	spore germination
EXW56_14135	COG4912	Dna alkylation repair
EXW56_14160	COG2814	Major facilitator Superfamily
EXW56_14165	COG1368	sulfuric ester hydrolase activity
EXW56_14175	COG0488	(ABC) transporter
EXW56_14180	COG2409	Drug exporters of the RND superfamily
EXW56_14180	COG1033	growth of symbiont in host cell
EXW56_14185	COG1309	transcriptional regulator
EXW56_14195	COG2153	protein acetylation
EXW56_14205	COG0287	Prephenate dehydrogenase
EXW56_14220	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW56_14220	COG1605	Chorismate mutase
EXW56_14255	COG3584	3D domain protein
EXW56_14255	COG1388	LysM domain
EXW56_14265	COG0346	lactoylglutathione lyase activity
EXW56_14275	COG0277	FAD linked oxidase domain protein
EXW56_14295	COG2610	gluconate transmembrane transporter activity
EXW56_14300	COG1024	Enoyl-CoA hydratase
EXW56_14310	COG3829	transcription factor binding
EXW56_14310	COG3290	protein histidine kinase activity
EXW56_14320	COG0579	oxidoreductase
EXW56_14325	COG1879	ABC-type sugar transport system periplasmic component
EXW56_14335	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW56_14340	COG1129	ABC transporter
EXW56_14345	COG2390	Transcriptional regulator
EXW56_14350	COG1070	Carbohydrate kinase
EXW56_14365	COG2226	methyltransferase
EXW56_14390	COG0346	lactoylglutathione lyase activity
EXW56_14395	COG2329	Antibiotic biosynthesis monooxygenase
EXW56_14415	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW56_14420	COG2207	Transcriptional regulator
EXW56_14425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW56_14430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW56_14435	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW56_14440	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW56_14445	COG3239	Fatty acid desaturase
EXW56_14470	COG3842	ATPase activity
EXW56_14495	COG1175	transmembrane transport
EXW56_14500	COG1349	DNA-binding transcription factor activity
EXW56_14510	COG3655	Transcriptional regulator
EXW56_14525	COG4377	Putative membrane peptidase family (DUF2324)
EXW56_14535	COG3279	Response regulator of the LytR AlgR family
EXW56_14550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW56_14555	COG0346	lactoylglutathione lyase activity
EXW56_14585	COG0714	Associated with various cellular activities
EXW56_14605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW56_14610	COG0753	catalase activity
EXW56_14625	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW56_14640	COG0714	Associated with various cellular activities
EXW56_14715	COG0778	Nitroreductase
EXW56_14720	COG1846	Transcriptional regulator
EXW56_14750	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW56_14760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW56_14765	COG0824	Thioesterase
EXW56_14770	COG0318	PFAM AMP-dependent synthetase and ligase
EXW56_14775	COG0183	Belongs to the thiolase family
EXW56_14780	COG1024	Enoyl-CoA hydratase
EXW56_14785	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW56_14790	COG2723	6-phospho-beta-galactosidase activity
EXW56_14795	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW56_14800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW56_14815	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW56_14825	COG2508	Transcriptional regulator
EXW56_14830	COG2814	Major facilitator Superfamily
EXW56_14845	COG4884	unkown
EXW56_14845	COG3831	ATPase activity
EXW56_14865	COG2814	Major facilitator Superfamily
EXW56_14870	COG1136	(ABC) transporter
EXW56_14870	COG0577	efflux transmembrane transporter activity
EXW56_14885	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_14890	COG1309	transcriptional regulator
EXW56_14910	COG0456	acetyltransferase
EXW56_14925	COG0697	spore germination
EXW56_14930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW56_14950	COG0642	Histidine kinase
EXW56_14955	COG0745	RESPONSE REGULATOR receiver
EXW56_14960	COG0596	Alpha beta hydrolase
EXW56_14990	COG0730	response to heat
EXW56_15000	COG0833	amino acid
EXW56_15010	COG4335	DNA alkylation repair
EXW56_15035	COG0768	penicillin binding
EXW56_15050	COG3104	oligopeptide transport
EXW56_15065	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW56_15080	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW56_15085	COG1984	allophanate hydrolase subunit 2
EXW56_15090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW56_15095	COG1414	Transcriptional regulator
EXW56_15110	COG1960	acyl-CoA dehydrogenase activity
EXW56_15145	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW56_15165	COG3848	Pyruvate phosphate dikinase
EXW56_15165	COG0574	Belongs to the PEP-utilizing enzyme family
EXW56_15225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW56_15235	COG0798	PFAM Bile acid sodium symporter
EXW56_15240	COG0346	lactoylglutathione lyase activity
EXW56_15245	COG0640	Transcriptional regulator
EXW56_15260	COG0346	lactoylglutathione lyase activity
EXW56_15315	COG0745	RESPONSE REGULATOR receiver
EXW56_15320	COG3850	Histidine kinase
EXW56_15320	COG5002	protein histidine kinase activity
EXW56_15350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW56_15355	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW56_15375	COG2226	methyltransferase
EXW56_15390	COG1690	Belongs to the RtcB family
EXW56_15415	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW56_15430	COG1136	(ABC) transporter
EXW56_15435	COG0577	efflux transmembrane transporter activity
EXW56_15450	COG5002	protein histidine kinase activity
EXW56_15450	COG3850	Histidine kinase
EXW56_15460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW56_15505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW56_15525	COG1595	DNA-templated transcription, initiation
EXW56_15575	COG2814	Major facilitator Superfamily
EXW56_15765	COG1876	peptidase activity
EXW56_15770	COG2843	Capsule synthesis protein
EXW56_15785	COG0477	Major facilitator Superfamily
EXW56_15800	COG1846	Transcriptional regulator
EXW56_15805	COG2814	Major facilitator Superfamily
EXW56_15820	COG0076	glutamate decarboxylase activity
EXW56_15830	COG0561	phosphatase activity
EXW56_15920	COG1696	Membrane protein involved in D-alanine export
EXW56_15955	COG1329	Transcriptional regulator
EXW56_15995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW56_16015	COG2155	Conserved Protein
EXW56_16160	COG4187	Peptidase family M20/M25/M40
EXW56_16165	COG1414	Transcriptional regulator
EXW56_16175	COG0833	amino acid
EXW56_16190	COG2031	fatty acid transporter
EXW56_16200	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW56_16260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW56_16265	COG2356	endonuclease I
EXW56_16270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW56_16275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW56_16285	COG2197	response regulator
EXW56_16305	COG1785	Belongs to the alkaline phosphatase family
EXW56_16320	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_16330	COG1131	(ABC) transporter
EXW56_16350	COG0494	nUDIX hydrolase
EXW56_16360	COG1011	Hydrolase
EXW56_16365	COG2365	Tyrosine phosphatase family
EXW56_16395	COG0628	permease
EXW56_16410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW56_16415	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW56_16425	COG1253	flavin adenine dinucleotide binding
EXW56_16430	COG0789	Transcriptional regulator
EXW56_16435	COG0697	spore germination
EXW56_16445	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW56_16450	COG3813	Protein conserved in bacteria
EXW56_16455	COG4702	Belongs to the UPF0303 family
EXW56_16465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW56_16480	COG0494	nUDIX hydrolase
EXW56_16485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW56_16495	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_16505	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW56_16510	COG1733	regulation of RNA biosynthetic process
EXW56_16525	COG1191	sigma factor activity
EXW56_16570	COG0814	amino acid
EXW56_16600	COG1151	hydroxylamine reductase activity
EXW56_16605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW56_16630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW56_16640	COG2072	flavoprotein involved in K transport
EXW56_16690	COG1695	Transcriptional regulator
EXW56_16695	COG0604	alcohol dehydrogenase
EXW56_16700	COG1113	amino acid transport
EXW56_16720	COG5002	protein histidine kinase activity
EXW56_16725	COG0745	RESPONSE REGULATOR receiver
EXW56_16730	COG5002	protein histidine kinase activity
EXW56_16740	COG2814	Major facilitator Superfamily
EXW56_16755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW56_16760	COG1012	belongs to the aldehyde dehydrogenase family
EXW56_16770	COG0534	Mate efflux family protein
EXW56_16775	COG1012	belongs to the aldehyde dehydrogenase family
EXW56_16780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW56_16795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW56_16800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW56_16820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW56_16825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW56_16830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW56_16835	COG3739	integral membrane protein
EXW56_16855	COG0583	DNA-binding transcription factor activity
EXW56_16875	COG1193	negative regulation of DNA recombination
EXW56_16885	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW56_16890	COG1164	Oligoendopeptidase f
EXW56_16915	COG3781	membrane
EXW56_16930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW56_16955	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW56_16960	COG0457	Tetratricopeptide repeat
EXW56_16975	COG2808	Putative FMN-binding domain
EXW56_16980	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW56_16990	COG0277	FAD linked oxidase domain protein
EXW56_17015	COG2514	catechol 2,3-dioxygenase activity
EXW56_17020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW56_17025	COG1126	abc transporter atp-binding protein
EXW56_17030	COG0765	amino acid transport
EXW56_17035	COG2720	vancomycin resistance protein
EXW56_17060	COG0110	maltose O-acetyltransferase activity
EXW56_17070	COG1278	Cold shock
EXW56_17080	COG0716	FMN binding
EXW56_17090	COG1051	belongs to the nudix hydrolase family
EXW56_17110	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_17120	COG0165	Argininosuccinate lyase
EXW56_17135	COG4145	pantothenate transmembrane transporter activity
EXW56_17145	COG1012	belongs to the aldehyde dehydrogenase family
EXW56_17150	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_17160	COG1657	PFAM Prenyltransferase squalene oxidase
EXW56_17165	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW56_17170	COG2962	Rard protein
EXW56_17175	COG3326	Membrane
EXW56_17180	COG0531	amino acid
EXW56_17205	COG1737	Transcriptional regulator
EXW56_17210	COG2971	BadF BadG BcrA BcrD
EXW56_17220	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW56_17225	COG1486	melibiose metabolic process
EXW56_17235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW56_17260	COG2226	methyltransferase
EXW56_17265	COG4166	transmembrane transport
EXW56_17270	COG4166	transmembrane transport
EXW56_17275	COG4166	transmembrane transport
EXW56_17285	COG1131	(ABC) transporter
EXW56_17295	COG0673	inositol 2-dehydrogenase activity
EXW56_17300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW56_17305	COG0187	DNA topoisomerase II activity
EXW56_17310	COG1832	CoA-binding protein
EXW56_17315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW56_17320	COG0745	RESPONSE REGULATOR receiver
EXW56_17330	COG1328	CTP reductase activity
EXW56_17330	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW56_17340	COG4841	protein insertion into membrane
EXW56_17345	COG0824	Thioesterase
EXW56_17370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW56_17390	COG1132	(ABC) transporter
EXW56_17395	COG1266	CAAX protease self-immunity
EXW56_17400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW56_17430	COG2211	Major facilitator Superfamily
EXW56_17440	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW56_17455	COG0183	Belongs to the thiolase family
EXW56_17460	COG0318	PFAM AMP-dependent synthetase and ligase
EXW56_17465	COG1268	BioY protein
EXW56_17470	COG0318	PFAM AMP-dependent synthetase and ligase
EXW56_17510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW56_17520	COG5002	protein histidine kinase activity
EXW56_17530	COG0400	carboxylic ester hydrolase activity
EXW56_17540	COG0069	glutamate synthase activity
EXW56_17545	COG1902	pentaerythritol trinitrate reductase activity
EXW56_17550	COG1329	Transcriptional regulator
EXW56_17555	COG0010	Belongs to the arginase family
EXW56_17565	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW56_17570	COG2986	histidine ammonia-lyase
EXW56_17580	COG2226	methyltransferase
EXW56_17610	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW56_17615	COG0785	Cytochrome C biogenesis protein
EXW56_17630	COG1473	amidohydrolase
EXW56_17640	COG1131	(ABC) transporter
EXW56_17655	COG0583	DNA-binding transcription factor activity
EXW56_17665	COG1346	cytolysis
EXW56_17700	COG1132	(ABC) transporter
EXW56_17705	COG1132	(ABC) transporter
EXW56_17710	COG3763	UPF0154 protein
EXW56_17725	COG3639	organic phosphonate transmembrane transporter activity
EXW56_17730	COG3639	organic phosphonate transmembrane transporter activity
EXW56_17740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW56_17745	COG0737	Belongs to the 5'-nucleotidase family
EXW56_17755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW56_17760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW56_17775	COG1695	Transcriptional regulator
EXW56_17780	COG1132	(ABC) transporter
EXW56_17815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW56_17820	COG0110	maltose O-acetyltransferase activity
EXW56_17825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW56_17835	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW56_17835	COG3420	alginic acid biosynthetic process
EXW56_17840	COG1216	Glycosyl transferase, family 2
EXW56_17840	COG1442	glycosyl transferase family 8
EXW56_17845	COG0438	transferase activity, transferring glycosyl groups
EXW56_17875	COG1216	Glycosyl transferase, family 2
EXW56_17895	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW56_17895	COG0463	Glycosyl transferase, family 2
EXW56_17900	COG0438	transferase activity, transferring glycosyl groups
EXW56_17905	COG0438	transferase activity, transferring glycosyl groups
EXW56_17910	COG1086	Polysaccharide biosynthesis protein
EXW56_17915	COG0489	protein tyrosine kinase activity
EXW56_17920	COG3944	biosynthesis protein
EXW56_17925	COG0174	glutamine synthetase
EXW56_17930	COG0789	Transcriptional regulator
EXW56_17935	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW56_17940	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW56_17945	COG2860	membrane
EXW56_17950	COG0464	growth
EXW56_17970	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW56_17980	COG3584	3D domain protein
EXW56_17980	COG1388	LysM domain
EXW56_17985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW56_17985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW56_17985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW56_17990	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW56_17995	COG1349	DNA-binding transcription factor activity
EXW56_18000	COG1979	alcohol dehydrogenase
EXW56_18010	COG2322	membrane
EXW56_18020	COG1473	amidohydrolase
EXW56_18025	COG1408	metallophosphoesterase
EXW56_18030	COG2116	formate transmembrane transporter activity
EXW56_18045	COG2217	Heavy metal translocating P-type atpase
EXW56_18050	COG2608	mercury ion transmembrane transporter activity
EXW56_18055	COG1937	Protein conserved in bacteria
EXW56_18085	COG2819	hydrolase of the alpha beta superfamily
EXW56_18090	COG1120	ATPase activity
EXW56_18095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW56_18100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW56_18105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW56_18110	COG0708	Exodeoxyribonuclease III
EXW56_18115	COG2169	Transcriptional regulator
EXW56_18120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW56_18125	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW56_18130	COG2706	6-phosphogluconolactonase activity
EXW56_18135	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW56_18150	COG0346	lactoylglutathione lyase activity
EXW56_18155	COG3300	MHYT domain
EXW56_18155	COG5001	Diguanylate cyclase
EXW56_18195	COG1346	cytolysis
EXW56_18205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW56_18210	COG0596	Alpha beta hydrolase
EXW56_18210	COG2945	thiolester hydrolase activity
EXW56_18215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW56_18225	COG2188	Transcriptional regulator
EXW56_18230	COG2723	6-phospho-beta-galactosidase activity
EXW56_18240	COG3773	Cell wall hydrolase
EXW56_18250	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW56_18275	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW56_18280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW56_18285	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW56_18290	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW56_18290	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW56_18300	COG2359	stage V sporulation protein S
EXW56_18305	COG1692	metallophosphoesterase
EXW56_18310	COG1418	mRNA catabolic process
EXW56_18315	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW56_18320	COG1546	Belongs to the CinA family
EXW56_18320	COG1058	Belongs to the CinA family
EXW56_18325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW56_18330	COG1426	Protein conserved in bacteria
EXW56_18345	COG0300	oxidoreductase activity
EXW56_18350	COG0612	Peptidase, M16
EXW56_18355	COG0612	Peptidase, M16
EXW56_18360	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW56_18365	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW56_18370	COG3845	ABC transporter
EXW56_18375	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW56_18380	COG2188	Transcriptional regulator
EXW56_18390	COG1674	ftsk spoiiie
EXW56_18400	COG0740	serine-type endopeptidase activity
EXW56_18405	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW56_18415	COG0527	aspartate kinase activity
EXW56_18420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW56_18425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW56_18430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW56_18435	COG1873	PFAM PRC-barrel domain
EXW56_18440	COG0612	Peptidase, M16
EXW56_18445	COG0726	polysaccharide deacetylase
EXW56_18450	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW56_18460	COG0196	riboflavin kinase activity
EXW56_18470	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW56_18475	COG1550	Protein conserved in bacteria
EXW56_18480	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW56_18485	COG1358	cellular component organization or biogenesis
EXW56_18490	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW56_18495	COG0195	Participates in both transcription termination and antitermination
EXW56_18510	COG0442	prolyl-tRNA aminoacylation
EXW56_18515	COG0750	zinc metalloprotease
EXW56_18525	COG4589	Belongs to the CDS family
EXW56_18535	COG0233	cytoplasmic translational termination
EXW56_18540	COG0528	UMP kinase activity
EXW56_18545	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW56_18555	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW56_18560	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW56_18565	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW56_18570	COG4974	Belongs to the 'phage' integrase family
EXW56_18575	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW56_18580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW56_18585	COG0758	DNA mediated transformation
EXW56_18590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW56_18595	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW56_18600	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW56_18615	COG0335	large ribosomal subunit rRNA binding
EXW56_18620	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW56_18625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW56_18630	COG1837	Belongs to the UPF0109 family
EXW56_18640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW56_18650	COG0552	protein localization to endoplasmic reticulum
EXW56_18655	COG1196	nuclear chromosome segregation
EXW56_18660	COG0571	ribonuclease III activity
EXW56_18665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW56_18670	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_18675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW56_18680	COG0416	fatty acid biosynthetic process
EXW56_18690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW56_18695	COG1461	Dihydroxyacetone kinase
EXW56_18700	COG1302	Protein conserved in bacteria
EXW56_18715	COG1564	THIamine pyrophosphokinase
EXW56_18720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW56_18730	COG0515	serine threonine protein kinase
EXW56_18730	COG2815	serine threonine protein kinase
EXW56_18735	COG0631	protein serine/threonine phosphatase activity
EXW56_18740	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW56_18745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW56_18745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW56_18750	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW56_18755	COG0242	peptide deformylase activity
EXW56_18760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW56_18765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW56_18770	COG1758	RNA polymerase activity
EXW56_18785	COG1561	YicC-like family, N-terminal region
EXW56_18790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW56_18805	COG0006	proline dipeptidase activity
EXW56_18825	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW56_18850	COG0167	dihydroorotate dehydrogenase activity
EXW56_18855	COG0543	2 iron, 2 sulfur cluster binding
EXW56_18860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW56_18870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW56_18875	COG0540	Belongs to the ATCase OTCase family
EXW56_18885	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW56_18890	COG0564	pseudouridine synthase activity
EXW56_18910	COG3599	regulation of cell shape
EXW56_18915	COG2302	S4 RNA-binding domain
EXW56_18920	COG0762	integral membrane protein
EXW56_18925	COG1799	cell septum assembly
EXW56_18930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW56_18940	COG1873	PFAM PRC-barrel domain
EXW56_18945	COG1191	sigma factor activity
EXW56_18950	COG1191	sigma factor activity
EXW56_18960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW56_18965	COG0849	cell division
EXW56_18970	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW56_18985	COG0772	Belongs to the SEDS family
EXW56_18990	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW56_18995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW56_19000	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW56_19005	COG0768	penicillin binding
EXW56_19010	COG0768	penicillin binding
EXW56_19020	COG0275	rRNA processing
EXW56_19025	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW56_19030	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW56_19035	COG0454	-acetyltransferase
EXW56_19045	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW56_19050	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW56_19055	COG1323	Belongs to the UPF0348 family
EXW56_19060	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW56_19065	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW56_19070	COG3314	Sporulation integral membrane protein YlbJ
EXW56_19080	COG0742	ribosomal rna small subunit methyltransferase
EXW56_19090	COG4471	UPF0298 protein
EXW56_19095	COG3679	Belongs to the UPF0342 family
EXW56_19100	COG0406	alpha-ribazole phosphatase activity
EXW56_19115	COG2340	Cysteine-rich secretory protein family
EXW56_19125	COG3336	cytochrome c oxidase
EXW56_19150	COG0109	protoheme IX farnesyltransferase activity
EXW56_19155	COG1612	heme a metabolic process
EXW56_19160	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW56_19170	COG0772	Belongs to the SEDS family
EXW56_19175	COG4838	Belongs to the UPF0358 family
EXW56_19180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW56_19185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW56_19195	COG4896	Protein conserved in bacteria
EXW56_19210	COG1217	gtp-binding protein TYPA
EXW56_19220	COG0483	inositol monophosphate 1-phosphatase activity
EXW56_19230	COG4493	Belongs to the UPF0637 family
EXW56_19235	COG4476	Belongs to the UPF0223 family
EXW56_19240	COG1982	Orn Lys Arg decarboxylase major
EXW56_19295	COG0022	dehydrogenase e1 component
EXW56_19300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW56_19315	COG0561	phosphatase activity
EXW56_19325	COG5503	Protein of unknown function (DUF1447)
EXW56_19330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW56_19335	COG0569	domain protein
EXW56_19345	COG1473	amidohydrolase
EXW56_19350	COG2171	N-acyltransferase activity
EXW56_19355	COG0583	DNA-binding transcription factor activity
EXW56_19360	COG0517	IMP dehydrogenase activity
EXW56_19370	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW56_19380	COG4703	Protein of unknown function (DUF1797)
EXW56_19395	COG2200	EAL domain
EXW56_19400	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_19405	COG1408	metallophosphoesterase
EXW56_19450	COG2814	Major facilitator Superfamily
EXW56_19460	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW56_19470	COG3209	COG3209 Rhs family protein
EXW56_19480	COG2205	protein histidine kinase activity
EXW56_19490	COG0436	Aminotransferase
EXW56_19495	COG1609	Transcriptional regulator
EXW56_19500	COG3833	ABC-type maltose transport systems, permease component
EXW56_19505	COG1175	transmembrane transport
EXW56_19510	COG2182	Extracellular solute-binding protein
EXW56_19525	COG0366	Alpha amylase catalytic
EXW56_19530	COG3842	ATPase activity
EXW56_19575	COG0183	Belongs to the thiolase family
EXW56_19610	COG1695	Transcriptional regulator
EXW56_19615	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_19625	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW56_19630	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW56_19635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW56_19640	COG0436	Aminotransferase
EXW56_19645	COG1850	ribulose-bisphosphate carboxylase activity
EXW56_19650	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW56_19655	COG0235	Class ii aldolase
EXW56_19660	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW56_19675	COG2084	Dehydrogenase
EXW56_19685	COG2199	diguanylate cyclase activity
EXW56_19690	COG0778	Nitroreductase
EXW56_19715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW56_19715	COG2190	(PTS) system
EXW56_19715	COG1263	PTS System
EXW56_19720	COG3711	transcriptional antiterminator
EXW56_19730	COG2188	Transcriptional regulator
EXW56_19735	COG0363	glucosamine-6-phosphate deaminase activity
EXW56_19740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW56_19750	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW56_19760	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW56_19770	COG1547	Domain of unknown function (DUF309)
EXW56_19780	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW56_19785	COG4086	secreted protein
EXW56_19790	COG0561	phosphatase activity
EXW56_19795	COG0697	spore germination
EXW56_19810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW56_19850	COG1686	Belongs to the peptidase S11 family
EXW56_19860	COG1725	Transcriptional regulator
EXW56_19865	COG1131	(ABC) transporter
EXW56_19890	COG1846	Transcriptional regulator
EXW56_19905	COG0598	Magnesium transport protein CorA
EXW56_19930	COG4974	Belongs to the 'phage' integrase family
EXW56_19940	COG0735	belongs to the Fur family
EXW56_19945	COG1300	Membrane
EXW56_19965	COG0667	Aldo Keto reductase
EXW56_19970	COG0656	L-ascorbic acid biosynthetic process
EXW56_19975	COG0456	acetyltransferase
EXW56_19975	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW56_19985	COG0737	Belongs to the 5'-nucleotidase family
EXW56_19985	COG1525	nuclease
EXW56_19985	COG4085	toxin activity
EXW56_19990	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW56_20000	COG0596	Alpha beta hydrolase
EXW56_20005	COG2056	Na+-H+ antiporter family
EXW56_20010	COG1609	Transcriptional regulator
EXW56_20015	COG0456	acetyltransferase
EXW56_20020	COG1073	alpha beta
EXW56_20035	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW56_20035	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW56_20040	COG0307	riboflavin synthase, alpha
EXW56_20045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW56_20045	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW56_20060	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW56_20070	COG2226	methyltransferase
EXW56_20070	COG1073	alpha beta
EXW56_20075	COG0156	8-amino-7-oxononanoate synthase activity
EXW56_20085	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW56_20100	COG1757	Na H antiporter
EXW56_20105	COG0737	Belongs to the 5'-nucleotidase family
EXW56_20115	COG1522	sequence-specific DNA binding
EXW56_20135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW56_20140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW56_20150	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW56_20160	COG0300	oxidoreductase activity
EXW56_20165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW56_20170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW56_20175	COG1760	l-serine dehydratase
EXW56_20180	COG1760	l-serine dehydratase
EXW56_20190	COG1234	tRNA 3'-trailer cleavage
EXW56_20220	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW56_20225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW56_20235	COG1376	ErfK ybiS ycfS ynhG family protein
EXW56_20240	COG4129	membrane
EXW56_20245	COG1126	abc transporter atp-binding protein
EXW56_20250	COG0765	amino acid transport
EXW56_20255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW56_20270	COG2816	NAD+ diphosphatase activity
EXW56_20275	COG2323	membrane
EXW56_20280	COG0772	Belongs to the SEDS family
EXW56_20285	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW56_20290	COG0022	dehydrogenase e1 component
EXW56_20295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW56_20300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW56_20305	COG3426	butyrate kinase activity
EXW56_20315	COG0280	phosphate acetyltransferase
EXW56_20325	COG3829	transcription factor binding
EXW56_20325	COG3290	protein histidine kinase activity
EXW56_20335	COG0584	glycerophosphoryl diester phosphodiesterase
EXW56_20340	COG3093	addiction module antidote protein HigA
EXW56_20350	COG0745	RESPONSE REGULATOR receiver
EXW56_20360	COG0750	zinc metalloprotease
EXW56_20365	COG0497	DNA recombination
EXW56_20370	COG1438	arginine binding
EXW56_20375	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW56_20380	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW56_20385	COG0142	geranyltranstransferase activity
EXW56_20390	COG1722	exodeoxyribonuclease VII activity
EXW56_20400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW56_20405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW56_20410	COG1302	Protein conserved in bacteria
EXW56_20415	COG0439	Biotin carboxylase
EXW56_20420	COG0511	ligase activity, forming carbon-carbon bonds
EXW56_20465	COG3854	ATPases associated with a variety of cellular activities
EXW56_20480	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW56_20485	COG0006	proline dipeptidase activity
EXW56_20500	COG3872	metal-dependent enzyme
EXW56_20510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW56_20545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW56_20555	COG1609	Transcriptional regulator
EXW56_20565	COG2076	Multidrug Resistance protein
EXW56_20570	COG2076	Multidrug Resistance protein
EXW56_20610	COG1725	Transcriptional regulator
EXW56_20625	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW56_20630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW56_20635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW56_20640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW56_20670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW56_20695	COG4970	Tfp pilus assembly protein FimT
EXW56_20700	COG4537	Required for transformation and DNA binding
EXW56_20705	COG1459	type II secretion system
EXW56_20710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW56_20770	COG0646	methionine synthase
EXW56_20770	COG1410	methionine synthase
EXW56_20775	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW56_20775	COG0646	methionine synthase
EXW56_20780	COG0626	cystathionine gamma-synthase activity
EXW56_20785	COG0626	cystathionine gamma-synthase activity
EXW56_20805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW56_20815	COG1940	carbohydrate kinase activity
EXW56_20820	COG4483	Protein conserved in bacteria
EXW56_20825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW56_20830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW56_20835	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW56_20840	COG0704	Plays a role in the regulation of phosphate uptake
EXW56_20850	COG0581	inorganic phosphate transmembrane transporter activity
EXW56_20855	COG0573	inorganic phosphate transmembrane transporter activity
EXW56_20860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW56_20865	COG0768	penicillin binding
EXW56_20870	COG0477	Major facilitator Superfamily
EXW56_20875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW56_20895	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW56_20900	COG0735	belongs to the Fur family
EXW56_20905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW56_20910	COG1121	(ABC) transporter
EXW56_20915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW56_20925	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW56_20945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW56_20950	COG2384	SAM-dependent methyltransferase
EXW56_20955	COG2010	Cytochrome c
EXW56_20960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW56_20965	COG0358	DNA primase activity
EXW56_20975	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW56_20980	COG0517	IMP dehydrogenase activity
EXW56_20985	COG1381	Involved in DNA repair and RecF pathway recombination
EXW56_20995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW56_21000	COG0295	cytidine deaminase activity
EXW56_21005	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW56_21010	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW56_21015	COG1480	7TM receptor with intracellular HD hydrolase
EXW56_21020	COG1702	phosphate starvation-inducible protein PhoH
EXW56_21035	COG1610	YqeY-like protein
EXW56_21040	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW56_21050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW56_21055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW56_21065	COG0484	heat shock protein binding
EXW56_21070	COG0443	Heat shock 70 kDa protein
EXW56_21080	COG1420	regulation of RNA biosynthetic process
EXW56_21085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW56_21090	COG1733	regulation of RNA biosynthetic process
EXW56_21095	COG0481	GTPase activity
EXW56_21105	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW56_21110	COG0268	Binds directly to 16S ribosomal RNA
EXW56_21115	COG1466	dna polymerase III delta subunit
EXW56_21125	COG2333	competence protein COMEC
EXW56_21125	COG0658	competence protein
EXW56_21130	COG2131	deaminase
EXW56_21135	COG1555	photosystem II stabilization
EXW56_21135	COG1596	polysaccharide export
EXW56_21140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW56_21145	COG2226	methyltransferase
EXW56_21150	COG0799	negative regulation of ribosome biogenesis
EXW56_21155	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW56_21160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW56_21165	COG1534	Rna-binding protein
EXW56_21170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW56_21175	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW56_21180	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW56_21190	COG0688	phosphatidylethanolamine metabolic process
EXW56_21210	COG2357	RelA SpoT domain protein
EXW56_21220	COG1785	Belongs to the alkaline phosphatase family
EXW56_21230	COG2267	carboxylic ester hydrolase activity
EXW56_21265	COG1404	Belongs to the peptidase S8 family
EXW56_21270	COG3186	Phenylalanine-4-hydroxylase
EXW56_21280	COG2514	catechol 2,3-dioxygenase activity
EXW56_21285	COG2259	Doxx family
EXW56_21325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW56_21340	COG1012	belongs to the aldehyde dehydrogenase family
EXW56_21340	COG1454	alcohol dehydrogenase
EXW56_21345	COG0626	cystathionine gamma-synthase activity
EXW56_21350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW56_21355	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW56_21360	COG2226	methyltransferase
EXW56_21375	COG0768	penicillin binding
EXW56_21380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW56_21385	COG0572	uridine kinase
EXW56_21390	COG0826	peptidase U32
EXW56_21395	COG0826	peptidase U32
EXW56_21400	COG4122	O-methyltransferase activity
EXW56_21405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW56_21415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW56_21425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW56_21430	COG0628	permease
EXW56_21450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW56_21460	COG0482	sulfurtransferase activity
EXW56_21465	COG1104	cysteine desulfurase activity
EXW56_21470	COG1959	2 iron, 2 sulfur cluster binding
EXW56_21475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW56_21485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW56_21490	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW56_21500	COG1490	D-aminoacyl-tRNA deacylase activity
EXW56_21505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW56_21510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW56_21515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW56_21515	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW56_21520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW56_21525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW56_21525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW56_21535	COG2244	polysaccharide biosynthetic process
EXW56_21540	COG2323	membrane
EXW56_21550	COG1862	Preprotein translocase
EXW56_21555	COG0343	queuine tRNA-ribosyltransferase activity
EXW56_21560	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW56_21570	COG2255	four-way junction helicase activity
EXW56_21575	COG0632	four-way junction helicase activity
EXW56_21580	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW56_21605	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW56_21610	COG0157	Belongs to the NadC ModD family
EXW56_21615	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW56_21620	COG1104	cysteine desulfurase activity
EXW56_21625	COG1827	regulation of RNA biosynthetic process
EXW56_21630	COG2258	MOSC domain
EXW56_21635	COG0077	Prephenate dehydratase
EXW56_21640	COG0577	efflux transmembrane transporter activity
EXW56_21645	COG0577	efflux transmembrane transporter activity
EXW56_21650	COG1136	(ABC) transporter
EXW56_21655	COG5002	protein histidine kinase activity
EXW56_21660	COG0745	RESPONSE REGULATOR receiver
EXW56_21665	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW56_21670	COG3290	protein histidine kinase activity
EXW56_21680	COG2868	ribosomal protein
EXW56_21690	COG1530	ribonuclease E activity
EXW56_21695	COG1994	Peptidase M50
EXW56_21700	COG0739	heme binding
EXW56_21705	COG2894	cell division
EXW56_21710	COG0850	regulation of cytokinetic process
EXW56_21725	COG1077	Cell shape determining protein MreB Mrl
EXW56_21730	COG2003	Belongs to the UPF0758 family
EXW56_21735	COG0424	maF-like protein
EXW56_21750	COG0285	dihydrofolate synthase activity
EXW56_21765	COG1388	LysM domain
EXW56_21770	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW56_21775	COG0113	porphobilinogen synthase activity
EXW56_21780	COG1587	Uroporphyrinogen-III synthase
EXW56_21785	COG0181	hydroxymethylbilane synthase activity
EXW56_21790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW56_21795	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW56_21800	COG1846	Transcriptional regulator
EXW56_21805	COG1764	response to oxidative stress
EXW56_21810	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW56_21820	COG1067	ATP-dependent peptidase activity
EXW56_21820	COG0470	DNA polymerase III
EXW56_21830	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW56_21865	COG0622	Phosphoesterase
EXW56_21875	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW56_21880	COG5401	PFAM Sporulation and spore germination
EXW56_21895	COG2197	response regulator
EXW56_21900	COG2233	PERMEase
EXW56_21905	COG0402	S-adenosylhomocysteine deaminase activity
EXW56_21910	COG1983	PspC domain protein
EXW56_21915	COG1396	sequence-specific DNA binding
EXW56_21920	COG0697	spore germination
EXW56_21930	COG1959	2 iron, 2 sulfur cluster binding
EXW56_21935	COG1668	transmembrane transport
EXW56_21940	COG4152	abc transporter atp-binding protein
EXW56_21945	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW56_21950	COG1360	Flagellar Motor Protein
EXW56_21955	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW56_21960	COG1876	peptidase activity
EXW56_21965	COG0824	Thioesterase
EXW56_21970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW56_21975	COG1053	succinate dehydrogenase
EXW56_21980	COG2009	succinate dehydrogenase
EXW56_21985	COG1719	4-vinyl reductase, 4VR
EXW56_21990	COG0322	excinuclease ABC activity
EXW56_21995	COG3118	belongs to the thioredoxin family
EXW56_22000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW56_22005	COG2086	electron transfer activity
EXW56_22010	COG1024	Enoyl-CoA hydratase
EXW56_22015	COG1309	transcriptional regulator
EXW56_22020	COG0318	PFAM AMP-dependent synthetase and ligase
EXW56_22055	COG1131	(ABC) transporter
EXW56_22060	COG2205	protein histidine kinase activity
EXW56_22065	COG0745	RESPONSE REGULATOR receiver
EXW56_22070	COG4895	conserved protein (DUF2196)
EXW56_22075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW56_22085	COG4509	Sortase family
EXW56_22090	COG1120	ATPase activity
EXW56_22105	COG5386	Cell surface protein
EXW56_22115	COG5386	Cell surface protein
EXW56_22120	COG1114	Component of the transport system for branched-chain amino acids
EXW56_22125	COG1187	pseudouridine synthase activity
EXW56_22130	COG1193	negative regulation of DNA recombination
EXW56_22135	COG1796	DNA polymerase
EXW56_22135	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW56_22140	COG1286	toxin biosynthetic process
EXW56_22145	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW56_22150	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW56_22180	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW56_22185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW56_22195	COG1418	mRNA catabolic process
EXW56_22215	COG2814	Major facilitator Superfamily
EXW56_22220	COG1566	PFAM secretion protein HlyD family protein
EXW56_22225	COG1309	transcriptional regulator
EXW56_22230	COG1363	Peptidase, m42
EXW56_22240	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW56_22255	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW56_22270	COG1484	DNA-dependent DNA replication
EXW56_22275	COG3611	Membrane attachment protein
EXW56_22280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW56_22285	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW56_22290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW56_22295	COG0237	dephospho-CoA kinase activity
EXW56_22300	COG1971	Probably functions as a manganese efflux pump
EXW56_22310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW56_22310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW56_22315	COG5002	protein histidine kinase activity
EXW56_22320	COG0745	RESPONSE REGULATOR receiver
EXW56_22340	COG0538	isocitrate dehydrogenase activity
EXW56_22345	COG0372	Belongs to the citrate synthase family
EXW56_22360	COG0628	permease
EXW56_22365	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW56_22375	COG0205	6-phosphofructokinase activity
EXW56_22390	COG1725	Transcriptional regulator
EXW56_22395	COG0281	malic enzyme
EXW56_22400	COG0587	DNA-directed DNA polymerase activity
EXW56_22415	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW56_22435	COG4109	DRTGG domain
EXW56_22440	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW56_22445	COG0006	proline dipeptidase activity
EXW56_22480	COG0662	Cupin 2, conserved barrel domain protein
EXW56_22490	COG1476	TRANSCRIPTIONal
EXW56_22505	COG1028	Short-chain dehydrogenase reductase Sdr
EXW56_22510	COG0589	response to stress
EXW56_22530	COG0165	Argininosuccinate lyase
EXW56_22535	COG0137	argininosuccinate synthase activity
EXW56_22555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW56_22575	COG0827	DNA restriction-modification system
EXW56_22580	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW56_22585	COG3874	Sporulation protein YtfJ
EXW56_22600	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW56_22610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW56_22625	COG1104	cysteine desulfurase activity
EXW56_22630	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW56_22635	COG0583	DNA-binding transcription factor activity
EXW56_22640	COG0697	spore germination
EXW56_22645	COG1309	transcriptional regulator
EXW56_22650	COG1956	GAF domain-containing protein
EXW56_22655	COG0626	cystathionine gamma-synthase activity
EXW56_22660	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW56_22670	COG5444	nuclease activity
EXW56_22705	COG1595	DNA-templated transcription, initiation
EXW56_22715	COG0110	maltose O-acetyltransferase activity
EXW56_22720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW56_22725	COG0454	-acetyltransferase
EXW56_22730	COG0517	IMP dehydrogenase activity
EXW56_22735	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW56_22750	COG0745	RESPONSE REGULATOR receiver
EXW56_22755	COG5002	protein histidine kinase activity
EXW56_22760	COG0666	response to abiotic stimulus
EXW56_22770	COG1970	mechanosensitive ion channel activity
EXW56_22790	COG1609	Transcriptional regulator
EXW56_22795	COG4851	CamS sex pheromone cAM373 precursor
EXW56_22810	COG2309	aminopeptidase activity
EXW56_22835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW56_22845	COG1674	ftsk spoiiie
EXW56_22860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW56_22865	COG4848	Belongs to the UPF0354 family
EXW56_22870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW56_22875	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW56_22880	COG1363	Peptidase, m42
EXW56_22890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW56_22895	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW56_22905	COG0510	thiamine kinase activity
EXW56_22910	COG1523	belongs to the glycosyl hydrolase 13 family
EXW56_22920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW56_22925	COG1349	DNA-binding transcription factor activity
EXW56_22930	COG1187	pseudouridine synthase activity
EXW56_22935	COG2244	polysaccharide biosynthetic process
EXW56_22940	COG2081	HI0933 family
EXW56_22945	COG2814	Major facilitator Superfamily
EXW56_22955	COG3832	glyoxalase III activity
EXW56_22980	COG1329	Transcriptional regulator
EXW56_22995	COG0314	molybdopterin synthase activity
EXW56_23000	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW56_23005	COG0303	'Molybdopterin
EXW56_23010	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW56_23015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW56_23020	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW56_23040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW56_23050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW56_23090	COG0495	leucyl-tRNA aminoacylation
EXW56_23095	COG2814	Major facilitator Superfamily
EXW56_23100	COG0475	glutathione-regulated potassium exporter activity
EXW56_23105	COG0490	domain, Protein
EXW56_23110	COG0582	viral genome integration into host DNA
EXW56_23125	COG1136	(ABC) transporter
EXW56_23140	COG1242	4 iron, 4 sulfur cluster binding
EXW56_23145	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW56_23185	COG2267	carboxylic ester hydrolase activity
EXW56_23190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW56_23195	COG0671	phosphoesterase, PA-phosphatase related
EXW56_23200	COG0438	transferase activity, transferring glycosyl groups
EXW56_23210	COG1404	Belongs to the peptidase S8 family
EXW56_23215	COG2197	response regulator
EXW56_23220	COG4585	Histidine kinase
EXW56_23245	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW56_23250	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW56_23290	COG5002	protein histidine kinase activity
EXW56_23295	COG3852	Histidine kinase
EXW56_23300	COG0753	catalase activity
EXW56_23305	COG2267	carboxylic ester hydrolase activity
EXW56_23310	COG1368	sulfuric ester hydrolase activity
EXW56_23320	COG4895	conserved protein (DUF2196)
EXW56_23335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW56_23340	COG1116	anion transmembrane transporter activity
EXW56_23345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW56_23360	COG0546	phosphoglycolate phosphatase activity
EXW56_23365	COG0494	nUDIX hydrolase
EXW56_23405	COG1854	S-ribosylhomocysteine lyase activity
EXW56_23415	COG0288	reversible hydration of carbon dioxide
EXW56_23420	COG1271	oxidase subunit
EXW56_23425	COG1294	oxidase, subunit
EXW56_23440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW56_23465	COG1842	Phage shock protein A
EXW56_23490	COG3859	Proton-coupled thiamine transporter YuaJ
EXW56_23495	COG5002	protein histidine kinase activity
EXW56_23500	COG0745	RESPONSE REGULATOR receiver
EXW56_23525	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW56_23530	COG1597	lipid kinase activity
EXW56_23560	COG1136	(ABC) transporter
EXW56_23575	COG5002	protein histidine kinase activity
EXW56_23585	COG0586	Pfam SNARE associated Golgi protein
EXW56_23595	COG0577	efflux transmembrane transporter activity
EXW56_23600	COG1136	(ABC) transporter
EXW56_23605	COG3708	Transcriptional regulator
EXW56_23605	COG2207	Transcriptional regulator
EXW56_23615	COG1131	(ABC) transporter
EXW56_23620	COG5658	integral membrane protein
EXW56_23625	COG5658	integral membrane protein
EXW56_23630	COG0640	Transcriptional regulator
EXW56_23635	COG0745	RESPONSE REGULATOR receiver
EXW56_23640	COG2205	protein histidine kinase activity
EXW56_23645	COG0577	efflux transmembrane transporter activity
EXW56_23650	COG0577	efflux transmembrane transporter activity
EXW56_23655	COG1136	(ABC) transporter
EXW56_23660	COG0577	efflux transmembrane transporter activity
EXW56_23670	COG2188	Transcriptional regulator
EXW56_23690	COG3964	amidohydrolase
EXW56_23720	COG4948	Mandelate Racemase Muconate Lactonizing
EXW56_23725	COG0318	PFAM AMP-dependent synthetase and ligase
EXW56_23730	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW56_23735	COG0596	Alpha beta hydrolase
EXW56_23740	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW56_23745	COG1169	isochorismate synthase
EXW56_23750	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW56_23755	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW56_23760	COG1278	Cold shock
EXW56_23775	COG1051	belongs to the nudix hydrolase family
EXW56_23790	COG0058	SHG alpha-glucan phosphorylase activity
EXW56_23800	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW56_23805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW56_23810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW56_23915	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW56_23950	COG1285	pathogenesis
EXW56_23955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW56_23965	COG0166	Belongs to the GPI family
EXW56_23975	COG2155	Conserved Protein
EXW56_23980	COG1098	S1 RNA binding domain
EXW56_23985	COG0436	Aminotransferase
EXW56_23990	COG1522	sequence-specific DNA binding
EXW56_23995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW56_24000	COG2267	carboxylic ester hydrolase activity
EXW56_24010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW56_24025	COG5018	Exonuclease
EXW56_24030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW56_24050	COG2050	protein possibly involved in aromatic compounds catabolism
EXW56_24060	COG1268	BioY protein
EXW56_24065	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW56_24070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW56_24080	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW56_24095	COG2076	Multidrug Resistance protein
EXW56_24100	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EXW56_24105	COG3584	3D domain protein
EXW56_24120	COG1252	NADH dehydrogenase
EXW56_24125	COG0492	ferredoxin-NADP+ reductase activity
EXW56_24130	COG3708	Transcriptional regulator
EXW56_24145	COG1683	Conserved Protein
EXW56_24155	COG0316	Belongs to the HesB IscA family
EXW56_24160	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW56_24165	COG4844	belongs to the
EXW56_24170	COG1252	NADH dehydrogenase
EXW56_24180	COG2274	protein secretion by the type I secretion system
EXW56_24185	COG0390	transport system, permease component
EXW56_24190	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW56_24210	COG4837	Protein of unknown function (DUF1462)
EXW56_24215	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW56_24225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW56_24230	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW56_24245	COG1136	(ABC) transporter
EXW56_24245	COG0577	efflux transmembrane transporter activity
EXW56_24250	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW56_24260	COG0647	UMP catabolic process
EXW56_24270	COG2445	Protein of unknown function DUF86
EXW56_24275	COG1494	fructose-1,6-bisphosphatase
EXW56_24300	COG4470	Protein conserved in bacteria
EXW56_24310	COG0789	Transcriptional regulator
EXW56_24315	COG4377	Putative membrane peptidase family (DUF2324)
EXW56_24340	COG0739	heme binding
EXW56_24350	COG3377	Domain of unknown function (DUF1805)
EXW56_24355	COG0737	Belongs to the 5'-nucleotidase family
EXW56_24370	COG0719	Fe-S assembly protein
EXW56_24375	COG0822	iron-sulfur transferase activity
EXW56_24380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW56_24385	COG0719	Fe-S assembly protein
EXW56_24390	COG0396	ATPase activity
EXW56_24395	COG1464	Belongs to the NlpA lipoprotein family
EXW56_24400	COG1464	Belongs to the NlpA lipoprotein family
EXW56_24405	COG2011	ABC-type metal ion transport system permease component
EXW56_24425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW56_24430	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW56_24435	COG0509	glycine decarboxylation via glycine cleavage system
EXW56_24440	COG1393	Belongs to the ArsC family
EXW56_24475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW56_24480	COG1960	acyl-CoA dehydrogenase activity
EXW56_24485	COG0183	Belongs to the thiolase family
EXW56_24490	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW56_24490	COG1024	Enoyl-CoA hydratase
EXW56_24500	COG1686	Belongs to the peptidase S11 family
EXW56_24505	COG0506	proline dehydrogenase activity
EXW56_24515	COG0011	TIGRFAM Protein of
EXW56_24520	COG0840	transmembrane signaling receptor activity
EXW56_24535	COG2814	Major facilitator Superfamily
EXW56_24540	COG0531	amino acid
EXW56_24560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW56_24590	COG0586	Pfam SNARE associated Golgi protein
EXW56_24600	COG1376	ErfK ybiS ycfS ynhG family protein
EXW56_24605	COG0745	RESPONSE REGULATOR receiver
EXW56_24610	COG5002	protein histidine kinase activity
EXW56_24625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW56_24635	COG0840	transmembrane signaling receptor activity
EXW56_24640	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW56_24645	COG3227	Zinc metalloprotease (Elastase)
EXW56_24665	COG0586	Pfam SNARE associated Golgi protein
EXW56_24670	COG0475	glutathione-regulated potassium exporter activity
EXW56_24675	COG0490	domain, Protein
EXW56_24680	COG1115	amino acid carrier protein
EXW56_24685	COG0783	Belongs to the Dps family
EXW56_24700	COG2318	DinB family
EXW56_24710	COG1611	Belongs to the LOG family
EXW56_24720	COG1528	Iron-storage protein
EXW56_24725	COG2311	Membrane
EXW56_24730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW56_24735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW56_24740	COG1115	amino acid carrier protein
EXW56_24745	COG1115	amino acid carrier protein
EXW56_24750	COG2910	NAD(P)H-binding
EXW56_24760	COG0656	L-ascorbic acid biosynthetic process
EXW56_24765	COG2814	Major facilitator Superfamily
EXW56_24770	COG1733	regulation of RNA biosynthetic process
EXW56_24780	COG1252	NADH dehydrogenase
EXW56_24805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW56_24825	COG3655	Transcriptional regulator
EXW56_24840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW56_24850	COG1733	regulation of RNA biosynthetic process
EXW56_24855	COG1522	sequence-specific DNA binding
EXW56_24860	COG0288	reversible hydration of carbon dioxide
EXW56_24865	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW56_24870	COG2233	PERMEase
EXW56_24910	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW56_24920	COG0557	exoribonuclease II activity
EXW56_24925	COG1647	Serine aminopeptidase, S33
EXW56_24930	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW56_24935	COG1346	cytolysis
EXW56_24960	COG0149	triose-phosphate isomerase activity
EXW56_24965	COG0126	phosphoglycerate kinase activity
EXW56_24970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW56_24985	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW56_25010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW56_25025	COG2323	membrane
EXW56_25035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW56_25040	COG1481	regulation of sporulation
EXW56_25045	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW56_25050	COG1660	Displays ATPase and GTPase activities
EXW56_25055	COG1051	belongs to the nudix hydrolase family
EXW56_25065	COG0492	ferredoxin-NADP+ reductase activity
EXW56_25070	COG0457	Tetratricopeptide repeat
EXW56_25075	COG0110	maltose O-acetyltransferase activity
EXW56_25080	COG0546	phosphoglycolate phosphatase activity
EXW56_25085	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW56_25090	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW56_25095	COG1950	PFAM Membrane protein of
EXW56_25100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW56_25120	COG0789	Transcriptional regulator
EXW56_25150	COG0583	DNA-binding transcription factor activity
EXW56_25155	COG0789	Transcriptional regulator
EXW56_25160	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW56_25165	COG0488	(ABC) transporter
EXW56_25175	COG1132	(ABC) transporter
EXW56_25180	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW56_25185	COG0583	DNA-binding transcription factor activity
EXW56_25190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW56_25195	COG3409	Peptidoglycan-binding domain 1 protein
EXW56_25195	COG0793	Belongs to the peptidase S41A family
EXW56_25200	COG2177	Part of the ABC transporter FtsEX involved in
EXW56_25205	COG2884	Cell division ATP-binding protein ftsE
EXW56_25245	COG1278	Cold shock
EXW56_25250	COG1040	competence protein
EXW56_25255	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW56_25260	COG0791	NLP P60 protein
EXW56_25260	COG1388	LysM domain
EXW56_25265	COG1733	regulation of RNA biosynthetic process
EXW56_25270	COG1307	EDD domain protein, DegV family
EXW56_25275	COG1739	Uncharacterized protein family UPF0029
EXW56_25280	COG1316	TRANSCRIPTIONal
EXW56_25285	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW56_25290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW56_25295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW56_25305	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW56_25305	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW56_25325	COG1486	melibiose metabolic process
EXW56_25330	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW56_25335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW56_25345	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW56_25355	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW56_25365	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW56_25370	COG1301	dicarboxylic acid transport
EXW56_25385	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW56_25390	COG1271	oxidase subunit
EXW56_25395	COG1294	oxidase, subunit
EXW56_25400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW56_25405	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW56_25410	COG1620	l-lactate permease
EXW56_25420	COG2389	metal-binding protein
EXW56_25435	COG1368	sulfuric ester hydrolase activity
EXW56_25450	COG0791	NLP P60 protein
EXW56_25450	COG1388	LysM domain
EXW56_25455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW56_25465	COG1215	transferase activity, transferring glycosyl groups
EXW56_25470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW56_25480	COG3584	3D domain protein
EXW56_25480	COG1388	LysM domain
EXW56_25495	COG4715	Zinc finger, swim domain protein
EXW56_25500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW56_25545	COG0577	efflux transmembrane transporter activity
EXW56_25550	COG1136	(ABC) transporter
EXW56_25575	COG3850	Histidine kinase
EXW56_25575	COG5002	protein histidine kinase activity
EXW56_25580	COG0745	RESPONSE REGULATOR receiver
EXW56_25585	COG1482	cell wall glycoprotein biosynthetic process
EXW56_25590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW56_25590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW56_25590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW56_25595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW56_25595	COG3711	transcriptional antiterminator
EXW56_25600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW56_25610	COG1316	TRANSCRIPTIONal
EXW56_25615	COG1482	cell wall glycoprotein biosynthetic process
EXW56_25620	COG0662	Cupin 2, conserved barrel domain protein
EXW56_25620	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EXW56_25640	COG0438	transferase activity, transferring glycosyl groups
EXW56_25645	COG1215	transferase activity, transferring glycosyl groups
EXW56_25650	COG2244	polysaccharide biosynthetic process
EXW56_25675	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW56_25680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW56_25685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW56_25690	COG4464	protein tyrosine phosphatase activity
EXW56_25695	COG0489	protein tyrosine kinase activity
EXW56_25700	COG3944	biosynthesis protein
EXW56_25705	COG0489	protein tyrosine kinase activity
EXW56_25720	COG1609	Transcriptional regulator
EXW56_25730	COG0739	heme binding
EXW56_25745	COG3279	Response regulator of the LytR AlgR family
EXW56_25750	COG2385	sporulation resulting in formation of a cellular spore
EXW56_25765	COG4836	Membrane
EXW56_25770	COG1007	ATP synthesis coupled electron transport
EXW56_25775	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW56_25780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW56_25785	COG0713	ATP synthesis coupled electron transport
EXW56_25790	COG0839	Belongs to the complex I subunit 6 family
EXW56_25800	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW56_25805	COG0649	NAD binding
EXW56_25810	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW56_25815	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW56_25820	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW56_25825	COG5001	Diguanylate cyclase
EXW56_25825	COG3300	MHYT domain
EXW56_25840	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW56_25845	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW56_25855	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW56_25865	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW56_25875	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW56_25900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW56_25910	COG0698	ribose 5-phosphate isomerase
EXW56_25920	COG2190	(PTS) system
EXW56_25925	COG2259	Doxx family
EXW56_25930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW56_25940	COG1971	Probably functions as a manganese efflux pump
EXW56_25945	COG0009	L-threonylcarbamoyladenylate synthase
EXW56_25980	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW56_25985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW56_25990	COG1435	thymidine kinase activity
EXW56_26000	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW56_26005	COG1494	fructose-1,6-bisphosphatase
EXW56_26025	COG4821	SIS domain
EXW56_26030	COG0504	CTP synthase activity
EXW56_26045	COG1960	acyl-CoA dehydrogenase activity
EXW56_26050	COG1960	acyl-CoA dehydrogenase activity
EXW56_26055	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW56_26060	COG0183	Belongs to the thiolase family
EXW56_26065	COG0247	lactate metabolic process
EXW56_26065	COG2181	nitrate reductase activity
EXW56_26070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW56_26075	COG4294	response to UV
EXW56_26080	COG5001	Diguanylate cyclase
EXW56_26080	COG3300	MHYT domain
EXW56_26100	COG2197	response regulator
EXW56_26105	COG4585	Histidine kinase
EXW56_26110	COG0842	Transport permease protein
EXW56_26115	COG1131	(ABC) transporter
EXW56_26120	COG0024	Methionine aminopeptidase
EXW56_26125	COG2234	aminopeptidase activity
EXW56_26140	COG4506	Protein conserved in bacteria
EXW56_26145	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW56_26160	COG0010	Belongs to the arginase family
EXW56_26170	COG2814	Major facilitator Superfamily
EXW56_26175	COG0789	Transcriptional regulator
EXW56_26180	COG0584	glycerophosphoryl diester phosphodiesterase
EXW56_26185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW56_26195	COG1994	Peptidase M50
EXW56_26205	COG1078	dGTPase activity
EXW56_26210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW56_26215	COG1120	ATPase activity
EXW56_26220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW56_26225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW56_26230	COG4844	belongs to the
EXW56_26245	COG0280	phosphate acetyltransferase
EXW56_26250	COG3253	May function as heme-dependent peroxidase
EXW56_26260	COG3773	Cell wall hydrolase
EXW56_26270	COG2363	Small membrane protein
EXW56_26280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW56_26285	COG2233	PERMEase
EXW56_26290	COG0561	phosphatase activity
EXW56_26295	COG2814	Major facilitator Superfamily
EXW56_26300	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW56_26305	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW56_26310	COG1131	(ABC) transporter
EXW56_26315	COG2755	lipolytic protein G-D-S-L family
EXW56_26320	COG1609	Transcriptional regulator
EXW56_26330	COG0460	homoserine dehydrogenase
EXW56_26335	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW56_26340	COG2873	o-acetylhomoserine
EXW56_26350	COG1011	Hydrolase
EXW56_26355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW56_26365	COG2197	response regulator
EXW56_26370	COG2203	Gaf domain
EXW56_26370	COG4585	Histidine kinase
EXW56_26375	COG0351	phosphomethylpyrimidine kinase
EXW56_26380	COG3706	GGDEF domain
EXW56_26385	COG2879	small protein
EXW56_26390	COG1966	Carbon starvation protein
EXW56_26395	COG3279	Response regulator of the LytR AlgR family
EXW56_26400	COG0477	Major facilitator Superfamily
EXW56_26430	COG0840	transmembrane signaling receptor activity
EXW56_26440	COG1607	acyl-coa hydrolase
EXW56_26445	COG1216	Glycosyl transferase, family 2
EXW56_26455	COG1216	Glycosyl transferase, family 2
EXW56_26470	COG1309	transcriptional regulator
EXW56_26475	COG0488	(ABC) transporter
EXW56_26480	COG1309	transcriptional regulator
EXW56_26485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW56_26490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW56_26490	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW56_26495	COG0628	permease
EXW56_26505	COG1380	Effector of murein hydrolase LrgA
EXW56_26510	COG3279	Response regulator of the LytR AlgR family
EXW56_26515	COG3275	phosphorelay sensor kinase activity
EXW56_26520	COG2814	Major facilitator Superfamily
EXW56_26525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW56_26530	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW56_26575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW56_26580	COG1272	protein, Hemolysin III
EXW56_26605	COG1164	Oligoendopeptidase f
EXW56_26620	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW56_26630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW56_26635	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW56_26640	COG4853	Protein conserved in bacteria
EXW56_26650	COG5002	protein histidine kinase activity
EXW56_26655	COG0745	RESPONSE REGULATOR receiver
EXW56_26685	COG0305	Participates in initiation and elongation during chromosome replication
EXW56_26695	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW56_26700	COG4241	membrane
EXW56_26710	COG0629	single-stranded DNA binding
EXW56_26720	COG0012	GTP binding
EXW56_26725	COG4481	Protein conserved in bacteria
EXW56_26730	COG0668	transmembrane transport
EXW56_26740	COG1475	DNA binding
EXW56_26745	COG1192	Involved in chromosome partitioning
EXW56_26750	COG1475	DNA binding
EXW56_26760	COG0445	tRNA wobble uridine modification
EXW56_26765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW56_26770	COG1847	R3H domain protein
EXW56_26775	COG0706	membrane insertase activity
EXW56_26780	COG0594	ribonuclease P activity
EXW56_26785	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW56_26820	COG0577	efflux transmembrane transporter activity
EXW56_26820	COG1136	(ABC) transporter
EXW56_26825	COG0582	viral genome integration into host DNA
EXW56_26840	COG1484	DNA-dependent DNA replication
EXW56_26985	COG0322	excinuclease ABC activity
EXW56_26995	COG5484	DNA packaging
EXW56_27085	COG4824	toxin secretion phage lysis holin
EXW56_27140	COG1396	sequence-specific DNA binding
EXW56_27330	COG2732	(Barnase) inhibitor
EXW56_27415	COG5002	protein histidine kinase activity
EXW56_27430	COG1279	arginine transmembrane transporter activity
EXW56_27435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW56_27460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW56_27490	COG0531	amino acid
EXW56_27500	COG3338	carbonate dehydratase activity
EXW56_27510	COG5002	protein histidine kinase activity
EXW56_27530	COG5002	protein histidine kinase activity
EXW56_27590	COG4565	transcriptional regulatory protein
EXW56_27595	COG3290	protein histidine kinase activity
EXW56_27600	COG3227	Zinc metalloprotease (Elastase)
EXW56_27655	COG1595	DNA-templated transcription, initiation
EXW56_27680	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EXW56_27735	COG1476	TRANSCRIPTIONal
EXW56_27805	COG0745	RESPONSE REGULATOR receiver
EXW56_27810	COG5002	protein histidine kinase activity
EXW56_27865	COG0697	spore germination
EXW56_27870	COG0814	amino acid
EXW56_27905	COG1329	Transcriptional regulator
EXW56_27955	COG0494	nUDIX hydrolase
EXW56_28050	COG1192	Involved in chromosome partitioning