locus-tag	class	description
EXW42_00010	COG5002	protein histidine kinase activity
EXW42_00015	COG3852	Histidine kinase
EXW42_00020	COG0753	catalase activity
EXW42_00025	COG2267	carboxylic ester hydrolase activity
EXW42_00035	COG1368	sulfuric ester hydrolase activity
EXW42_00045	COG4895	conserved protein (DUF2196)
EXW42_00060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW42_00065	COG1116	anion transmembrane transporter activity
EXW42_00070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW42_00095	COG0494	nUDIX hydrolase
EXW42_00135	COG2076	Multidrug Resistance protein
EXW42_00140	COG2076	Multidrug Resistance protein
EXW42_00145	COG0789	Transcriptional regulator
EXW42_00150	COG1854	S-ribosylhomocysteine lyase activity
EXW42_00160	COG0288	reversible hydration of carbon dioxide
EXW42_00165	COG1271	oxidase subunit
EXW42_00170	COG1294	oxidase, subunit
EXW42_00190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW42_00215	COG1842	Phage shock protein A
EXW42_00240	COG3859	Proton-coupled thiamine transporter YuaJ
EXW42_00245	COG5002	protein histidine kinase activity
EXW42_00250	COG0745	RESPONSE REGULATOR receiver
EXW42_00275	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW42_00280	COG1597	lipid kinase activity
EXW42_00325	COG0586	Pfam SNARE associated Golgi protein
EXW42_00340	COG0577	efflux transmembrane transporter activity
EXW42_00345	COG1136	(ABC) transporter
EXW42_00350	COG2207	Transcriptional regulator
EXW42_00350	COG3708	Transcriptional regulator
EXW42_00360	COG1131	(ABC) transporter
EXW42_00365	COG5658	integral membrane protein
EXW42_00370	COG0640	Transcriptional regulator
EXW42_00375	COG0745	RESPONSE REGULATOR receiver
EXW42_00380	COG2205	protein histidine kinase activity
EXW42_00385	COG0577	efflux transmembrane transporter activity
EXW42_00390	COG0577	efflux transmembrane transporter activity
EXW42_00395	COG1136	(ABC) transporter
EXW42_00400	COG0577	efflux transmembrane transporter activity
EXW42_00415	COG2188	Transcriptional regulator
EXW42_00435	COG3964	amidohydrolase
EXW42_00455	COG4948	Mandelate Racemase Muconate Lactonizing
EXW42_00460	COG0318	PFAM AMP-dependent synthetase and ligase
EXW42_00470	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW42_00480	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW42_00485	COG1169	isochorismate synthase
EXW42_00490	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW42_00495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW42_00500	COG1278	Cold shock
EXW42_00510	COG0789	Transcriptional regulator
EXW42_00520	COG0058	SHG alpha-glucan phosphorylase activity
EXW42_00530	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW42_00540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW42_00700	COG1285	pathogenesis
EXW42_00705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW42_00715	COG0166	Belongs to the GPI family
EXW42_00725	COG2155	Conserved Protein
EXW42_00730	COG1098	S1 RNA binding domain
EXW42_00735	COG0436	Aminotransferase
EXW42_00740	COG1522	sequence-specific DNA binding
EXW42_00745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW42_00750	COG2267	carboxylic ester hydrolase activity
EXW42_00760	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW42_00775	COG5018	Exonuclease
EXW42_00780	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW42_00800	COG2050	protein possibly involved in aromatic compounds catabolism
EXW42_00810	COG1268	BioY protein
EXW42_00820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW42_00825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW42_00835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW42_00840	COG3584	3D domain protein
EXW42_00855	COG1252	NADH dehydrogenase
EXW42_00860	COG0492	ferredoxin-NADP+ reductase activity
EXW42_00865	COG3708	Transcriptional regulator
EXW42_00880	COG1683	Conserved Protein
EXW42_00905	COG0316	Belongs to the HesB IscA family
EXW42_00910	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW42_00915	COG4844	belongs to the
EXW42_00920	COG1252	NADH dehydrogenase
EXW42_00930	COG0390	transport system, permease component
EXW42_00935	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW42_00970	COG4837	Protein of unknown function (DUF1462)
EXW42_00975	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW42_00985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW42_00990	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW42_01005	COG0577	efflux transmembrane transporter activity
EXW42_01005	COG1136	(ABC) transporter
EXW42_01010	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW42_01020	COG0647	UMP catabolic process
EXW42_01030	COG2445	Protein of unknown function DUF86
EXW42_01035	COG1494	fructose-1,6-bisphosphatase
EXW42_01050	COG4470	Protein conserved in bacteria
EXW42_01060	COG0789	Transcriptional regulator
EXW42_01065	COG4377	Putative membrane peptidase family (DUF2324)
EXW42_01085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW42_01090	COG0739	heme binding
EXW42_01100	COG3377	Domain of unknown function (DUF1805)
EXW42_01105	COG0737	Belongs to the 5'-nucleotidase family
EXW42_01110	COG1695	Transcriptional regulator
EXW42_01120	COG0719	Fe-S assembly protein
EXW42_01125	COG0822	iron-sulfur transferase activity
EXW42_01130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW42_01135	COG0719	Fe-S assembly protein
EXW42_01140	COG0396	ATPase activity
EXW42_01145	COG1464	Belongs to the NlpA lipoprotein family
EXW42_01150	COG1464	Belongs to the NlpA lipoprotein family
EXW42_01155	COG2011	ABC-type metal ion transport system permease component
EXW42_01160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW42_01170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW42_01175	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW42_01180	COG0509	glycine decarboxylation via glycine cleavage system
EXW42_01185	COG1393	Belongs to the ArsC family
EXW42_01220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW42_01225	COG1960	acyl-CoA dehydrogenase activity
EXW42_01230	COG0183	Belongs to the thiolase family
EXW42_01235	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW42_01235	COG1024	Enoyl-CoA hydratase
EXW42_01245	COG1686	Belongs to the peptidase S11 family
EXW42_01250	COG0506	proline dehydrogenase activity
EXW42_01260	COG0011	TIGRFAM Protein of
EXW42_01265	COG0840	transmembrane signaling receptor activity
EXW42_01280	COG2814	Major facilitator Superfamily
EXW42_01285	COG0531	amino acid
EXW42_01310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW42_01440	COG0586	Pfam SNARE associated Golgi protein
EXW42_01450	COG1376	ErfK ybiS ycfS ynhG family protein
EXW42_01455	COG0745	RESPONSE REGULATOR receiver
EXW42_01460	COG5002	protein histidine kinase activity
EXW42_01470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW42_01480	COG0840	transmembrane signaling receptor activity
EXW42_01485	COG0840	transmembrane signaling receptor activity
EXW42_01490	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW42_01495	COG3227	Zinc metalloprotease (Elastase)
EXW42_01500	COG1741	Belongs to the pirin family
EXW42_01515	COG0586	Pfam SNARE associated Golgi protein
EXW42_01520	COG0475	glutathione-regulated potassium exporter activity
EXW42_01525	COG0490	domain, Protein
EXW42_01530	COG1115	amino acid carrier protein
EXW42_01535	COG0783	Belongs to the Dps family
EXW42_01545	COG2318	DinB family
EXW42_01550	COG1611	Belongs to the LOG family
EXW42_01560	COG1528	Iron-storage protein
EXW42_01565	COG2311	Membrane
EXW42_01570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW42_01575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW42_01580	COG1115	amino acid carrier protein
EXW42_01585	COG1115	amino acid carrier protein
EXW42_01590	COG2910	NAD(P)H-binding
EXW42_01600	COG0656	L-ascorbic acid biosynthetic process
EXW42_01605	COG2814	Major facilitator Superfamily
EXW42_01610	COG1733	regulation of RNA biosynthetic process
EXW42_01620	COG1252	NADH dehydrogenase
EXW42_01640	COG3290	protein histidine kinase activity
EXW42_01640	COG0840	transmembrane signaling receptor activity
EXW42_01675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW42_01690	COG4224	UPF0291 protein
EXW42_01695	COG1335	isochorismatase
EXW42_01700	COG1522	sequence-specific DNA binding
EXW42_01710	COG1522	sequence-specific DNA binding
EXW42_01715	COG0288	reversible hydration of carbon dioxide
EXW42_01720	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW42_01725	COG2233	PERMEase
EXW42_01770	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW42_01780	COG0557	exoribonuclease II activity
EXW42_01785	COG1647	Serine aminopeptidase, S33
EXW42_01790	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW42_01795	COG1346	cytolysis
EXW42_01810	COG0148	phosphopyruvate hydratase activity
EXW42_01820	COG0149	triose-phosphate isomerase activity
EXW42_01825	COG0126	phosphoglycerate kinase activity
EXW42_01830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW42_01845	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW42_01880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW42_01895	COG2323	membrane
EXW42_01905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW42_01910	COG1481	regulation of sporulation
EXW42_01915	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW42_01920	COG1660	Displays ATPase and GTPase activities
EXW42_01925	COG1051	belongs to the nudix hydrolase family
EXW42_01935	COG0492	ferredoxin-NADP+ reductase activity
EXW42_01940	COG0457	Tetratricopeptide repeat
EXW42_01945	COG0110	maltose O-acetyltransferase activity
EXW42_01950	COG0546	phosphoglycolate phosphatase activity
EXW42_01955	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW42_01960	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW42_01965	COG1950	PFAM Membrane protein of
EXW42_01970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW42_01990	COG0789	Transcriptional regulator
EXW42_02025	COG0583	DNA-binding transcription factor activity
EXW42_02030	COG0789	Transcriptional regulator
EXW42_02035	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW42_02040	COG0488	(ABC) transporter
EXW42_02050	COG1132	(ABC) transporter
EXW42_02055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW42_02060	COG0793	Belongs to the peptidase S41A family
EXW42_02060	COG3409	Peptidoglycan-binding domain 1 protein
EXW42_02065	COG2177	Part of the ABC transporter FtsEX involved in
EXW42_02070	COG2884	Cell division ATP-binding protein ftsE
EXW42_02105	COG1131	(ABC) transporter
EXW42_02140	COG1278	Cold shock
EXW42_02145	COG1040	competence protein
EXW42_02150	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW42_02155	COG0791	NLP P60 protein
EXW42_02155	COG1388	LysM domain
EXW42_02160	COG1733	regulation of RNA biosynthetic process
EXW42_02165	COG1307	EDD domain protein, DegV family
EXW42_02170	COG1739	Uncharacterized protein family UPF0029
EXW42_02175	COG1316	TRANSCRIPTIONal
EXW42_02180	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW42_02185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW42_02190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW42_02200	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW42_02200	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW42_02220	COG1486	melibiose metabolic process
EXW42_02225	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW42_02230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW42_02250	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW42_02260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW42_02265	COG1301	dicarboxylic acid transport
EXW42_02285	COG1511	domain protein
EXW42_02290	COG0583	DNA-binding transcription factor activity
EXW42_02295	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW42_02300	COG1271	oxidase subunit
EXW42_02305	COG1294	oxidase, subunit
EXW42_02310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW42_02315	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW42_02320	COG1620	l-lactate permease
EXW42_02330	COG2389	metal-binding protein
EXW42_02340	COG1368	sulfuric ester hydrolase activity
EXW42_02350	COG0791	NLP P60 protein
EXW42_02350	COG1388	LysM domain
EXW42_02355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW42_02365	COG1215	transferase activity, transferring glycosyl groups
EXW42_02370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW42_02380	COG3584	3D domain protein
EXW42_02380	COG1388	LysM domain
EXW42_02390	COG4715	Zinc finger, swim domain protein
EXW42_02395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW42_02435	COG0577	efflux transmembrane transporter activity
EXW42_02440	COG1136	(ABC) transporter
EXW42_02475	COG3850	Histidine kinase
EXW42_02475	COG5002	protein histidine kinase activity
EXW42_02480	COG0745	RESPONSE REGULATOR receiver
EXW42_02490	COG1316	TRANSCRIPTIONal
EXW42_02500	COG0110	maltose O-acetyltransferase activity
EXW42_02520	COG0217	transcriptional regulatory protein
EXW42_02530	COG1215	transferase activity, transferring glycosyl groups
EXW42_02535	COG1045	serine acetyltransferase
EXW42_02540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW42_02545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW42_02550	COG1086	Polysaccharide biosynthesis protein
EXW42_02555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW42_02560	COG4464	protein tyrosine phosphatase activity
EXW42_02565	COG0489	protein tyrosine kinase activity
EXW42_02570	COG3944	biosynthesis protein
EXW42_02575	COG0489	protein tyrosine kinase activity
EXW42_02590	COG1609	Transcriptional regulator
EXW42_02600	COG0739	heme binding
EXW42_02615	COG3279	Response regulator of the LytR AlgR family
EXW42_02620	COG2385	sporulation resulting in formation of a cellular spore
EXW42_02635	COG4836	Membrane
EXW42_02640	COG1007	ATP synthesis coupled electron transport
EXW42_02645	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW42_02650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW42_02655	COG0713	ATP synthesis coupled electron transport
EXW42_02660	COG0839	Belongs to the complex I subunit 6 family
EXW42_02670	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW42_02675	COG0649	NAD binding
EXW42_02680	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW42_02685	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW42_02690	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW42_02695	COG3300	MHYT domain
EXW42_02695	COG5001	Diguanylate cyclase
EXW42_02710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW42_02715	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW42_02720	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW42_02725	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW42_02730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW42_02735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW42_02745	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW42_02770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW42_02780	COG0698	ribose 5-phosphate isomerase
EXW42_02790	COG2190	(PTS) system
EXW42_02795	COG2259	Doxx family
EXW42_02800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW42_02810	COG1971	Probably functions as a manganese efflux pump
EXW42_02815	COG0009	L-threonylcarbamoyladenylate synthase
EXW42_02830	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW42_02835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW42_02840	COG1435	thymidine kinase activity
EXW42_02850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW42_02860	COG1494	fructose-1,6-bisphosphatase
EXW42_02880	COG4821	SIS domain
EXW42_02885	COG0504	CTP synthase activity
EXW42_02890	COG3343	RNA polymerase activity
EXW42_02900	COG1960	acyl-CoA dehydrogenase activity
EXW42_02905	COG1960	acyl-CoA dehydrogenase activity
EXW42_02910	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW42_02915	COG0183	Belongs to the thiolase family
EXW42_02920	COG0247	lactate metabolic process
EXW42_02920	COG2181	nitrate reductase activity
EXW42_02925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW42_02930	COG4294	response to UV
EXW42_02935	COG5001	Diguanylate cyclase
EXW42_02935	COG3300	MHYT domain
EXW42_02950	COG3227	Zinc metalloprotease (Elastase)
EXW42_02955	COG2197	response regulator
EXW42_02960	COG4585	Histidine kinase
EXW42_02965	COG0842	Transport permease protein
EXW42_02970	COG1131	(ABC) transporter
EXW42_02975	COG0024	Methionine aminopeptidase
EXW42_02980	COG2234	aminopeptidase activity
EXW42_02995	COG4506	Protein conserved in bacteria
EXW42_03000	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW42_03015	COG0010	Belongs to the arginase family
EXW42_03020	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW42_03025	COG2814	Major facilitator Superfamily
EXW42_03030	COG0789	Transcriptional regulator
EXW42_03035	COG0584	glycerophosphoryl diester phosphodiesterase
EXW42_03040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW42_03050	COG1994	Peptidase M50
EXW42_03060	COG1078	dGTPase activity
EXW42_03065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW42_03070	COG1120	ATPase activity
EXW42_03075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW42_03080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW42_03085	COG4844	belongs to the
EXW42_03100	COG0280	phosphate acetyltransferase
EXW42_03105	COG3253	May function as heme-dependent peroxidase
EXW42_03115	COG3773	Cell wall hydrolase
EXW42_03125	COG2363	Small membrane protein
EXW42_03140	COG2233	PERMEase
EXW42_03145	COG0561	phosphatase activity
EXW42_03150	COG2814	Major facilitator Superfamily
EXW42_03155	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW42_03160	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW42_03165	COG1131	(ABC) transporter
EXW42_03170	COG2755	lipolytic protein G-D-S-L family
EXW42_03175	COG1609	Transcriptional regulator
EXW42_03185	COG0460	homoserine dehydrogenase
EXW42_03190	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW42_03195	COG2873	o-acetylhomoserine
EXW42_03205	COG1011	Hydrolase
EXW42_03210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW42_03220	COG2197	response regulator
EXW42_03225	COG2203	Gaf domain
EXW42_03225	COG4585	Histidine kinase
EXW42_03230	COG0351	phosphomethylpyrimidine kinase
EXW42_03235	COG3706	GGDEF domain
EXW42_03240	COG2879	small protein
EXW42_03245	COG1966	Carbon starvation protein
EXW42_03250	COG3279	Response regulator of the LytR AlgR family
EXW42_03255	COG0477	Major facilitator Superfamily
EXW42_03280	COG0840	transmembrane signaling receptor activity
EXW42_03290	COG1607	acyl-coa hydrolase
EXW42_03295	COG1216	Glycosyl transferase, family 2
EXW42_03305	COG1216	Glycosyl transferase, family 2
EXW42_03315	COG0488	(ABC) transporter
EXW42_03320	COG1696	Membrane protein involved in D-alanine export
EXW42_03330	COG1309	transcriptional regulator
EXW42_03335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW42_03340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW42_03340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW42_03345	COG0628	permease
EXW42_03355	COG1380	Effector of murein hydrolase LrgA
EXW42_03360	COG3279	Response regulator of the LytR AlgR family
EXW42_03365	COG3275	phosphorelay sensor kinase activity
EXW42_03370	COG2814	Major facilitator Superfamily
EXW42_03375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW42_03380	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW42_03390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW42_03440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW42_03445	COG1272	protein, Hemolysin III
EXW42_03475	COG1164	Oligoendopeptidase f
EXW42_03485	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW42_03495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW42_03500	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW42_03505	COG4853	Protein conserved in bacteria
EXW42_03515	COG5002	protein histidine kinase activity
EXW42_03520	COG0745	RESPONSE REGULATOR receiver
EXW42_03550	COG0305	Participates in initiation and elongation during chromosome replication
EXW42_03555	COG0359	binds to the 23S rRNA
EXW42_03560	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW42_03565	COG4241	membrane
EXW42_03575	COG0629	single-stranded DNA binding
EXW42_03580	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW42_03585	COG0012	GTP binding
EXW42_03590	COG4481	Protein conserved in bacteria
EXW42_03595	COG0668	transmembrane transport
EXW42_03605	COG1475	DNA binding
EXW42_03610	COG1192	Involved in chromosome partitioning
EXW42_03615	COG1475	DNA binding
EXW42_03620	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW42_03625	COG0445	tRNA wobble uridine modification
EXW42_03630	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW42_03635	COG1847	R3H domain protein
EXW42_03640	COG0706	membrane insertase activity
EXW42_03645	COG0594	ribonuclease P activity
EXW42_03650	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW42_03655	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW42_03660	COG0592	DNA-directed DNA polymerase activity
EXW42_03665	COG2501	S4 domain
EXW42_03670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW42_03675	COG0187	DNA topoisomerase II activity
EXW42_03680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW42_03715	COG0516	GMP reductase activity
EXW42_03715	COG0517	IMP dehydrogenase activity
EXW42_03720	COG1686	Belongs to the peptidase S11 family
EXW42_03725	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW42_03730	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW42_03750	COG1428	Deoxynucleoside kinase
EXW42_03755	COG1428	Deoxynucleoside kinase
EXW42_03760	COG1335	isochorismatase
EXW42_03765	COG0590	tRNA wobble adenosine to inosine editing
EXW42_03775	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW42_03780	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW42_03785	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW42_03830	COG1982	Orn Lys Arg decarboxylase major
EXW42_03835	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW42_03840	COG0470	DNA polymerase III
EXW42_03845	COG1774	PSP1 C-terminal conserved region
EXW42_03850	COG4467	Involved in initiation control of chromosome replication
EXW42_03855	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW42_03865	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW42_03870	COG2002	toxin-antitoxin pair type II binding
EXW42_03880	COG0084	hydrolase, TatD family'
EXW42_03890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW42_03900	COG4466	Protein conserved in bacteria
EXW42_03910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW42_03915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW42_03920	COG0251	oxidation-reduction process
EXW42_03925	COG2088	sporulation resulting in formation of a cellular spore
EXW42_03930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW42_03950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW42_03955	COG2002	toxin-antitoxin pair type II binding
EXW42_03960	COG2244	polysaccharide biosynthetic process
EXW42_03965	COG3956	TIGRFAM MazG family protein
EXW42_03970	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW42_03990	COG1098	S1 RNA binding domain
EXW42_04005	COG2208	phosphoserine phosphatase activity
EXW42_04015	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW42_04020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW42_04025	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW42_04030	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW42_04035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW42_04040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW42_04045	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW42_04050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW42_04055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW42_04060	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW42_04065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW42_04070	COG1396	sequence-specific DNA binding
EXW42_04075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW42_04080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW42_04165	COG3880	PFAM UvrB UvrC protein
EXW42_04170	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW42_04175	COG0542	response to heat
EXW42_04180	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW42_04185	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW42_04190	COG4956	integral membrane protein (PIN domain superfamily)
EXW42_04195	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW42_04205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW42_04210	COG1045	serine acetyltransferase
EXW42_04215	COG0215	cysteine-tRNA ligase activity
EXW42_04225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW42_04230	COG3688	RNA-binding protein containing a PIN domain
EXW42_04240	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW42_04245	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW42_04250	COG0250	Participates in transcription elongation, termination and antitermination
EXW42_04255	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW42_04260	COG0081	regulation of translation
EXW42_04265	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW42_04270	COG0222	ribosome binding
EXW42_04275	COG2813	Specifically methylates the guanine in position
EXW42_04280	COG0085	RNA polymerase activity
EXW42_04285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW42_04290	COG1358	cellular component organization or biogenesis
EXW42_04295	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW42_04305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW42_04310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW42_04315	COG0051	transcription antitermination factor activity, RNA binding
EXW42_04320	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW42_04325	COG0088	Forms part of the polypeptide exit tunnel
EXW42_04330	COG0089	rRNA binding
EXW42_04335	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW42_04340	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW42_04345	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW42_04360	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW42_04365	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW42_04375	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW42_04380	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW42_04390	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW42_04400	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW42_04410	COG1841	ribosomal large subunit assembly
EXW42_04415	COG0200	Binds to the 23S rRNA
EXW42_04420	COG0201	protein transport
EXW42_04425	COG0563	adenylate kinase activity
EXW42_04430	COG0024	Methionine aminopeptidase
EXW42_04440	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW42_04445	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW42_04450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW42_04475	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW42_04485	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW42_04490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW42_04500	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW42_04505	COG0489	protein tyrosine kinase activity
EXW42_04515	COG2194	sulfuric ester hydrolase activity
EXW42_04520	COG0726	polysaccharide deacetylase
EXW42_04600	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW42_04605	COG4856	YbbR-like protein
EXW42_04610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW42_04640	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_04645	COG2011	ABC-type metal ion transport system permease component
EXW42_04655	COG1464	Belongs to the NlpA lipoprotein family
EXW42_04660	COG0604	alcohol dehydrogenase
EXW42_04670	COG0277	FAD linked oxidase domain protein
EXW42_04675	COG2271	Major facilitator Superfamily
EXW42_04685	COG2814	Major facilitator Superfamily
EXW42_04700	COG0601	transmembrane transport
EXW42_04705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW42_04710	COG0444	Belongs to the ABC transporter superfamily
EXW42_04715	COG4608	Belongs to the ABC transporter superfamily
EXW42_04720	COG4166	transmembrane transport
EXW42_04730	COG2207	Transcriptional regulator
EXW42_04745	COG4166	transmembrane transport
EXW42_04750	COG4166	transmembrane transport
EXW42_04755	COG0656	L-ascorbic acid biosynthetic process
EXW42_04760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW42_04775	COG4149	molybdate abc transporter
EXW42_04780	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW42_04785	COG1910	domain protein
EXW42_04800	COG0697	spore germination
EXW42_04815	COG0204	Acyl-transferase
EXW42_04825	COG1609	Transcriptional regulator
EXW42_04835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW42_04850	COG5298	Protein conserved in bacteria
EXW42_04875	COG0488	(ABC) transporter
EXW42_04880	COG4585	Histidine kinase
EXW42_04885	COG2197	response regulator
EXW42_04890	COG1131	(ABC) transporter
EXW42_04895	COG0842	Transport permease protein
EXW42_04895	COG1511	domain protein
EXW42_04900	COG0842	Transport permease protein
EXW42_04910	COG0747	negative chemotaxis
EXW42_04920	COG0601	transmembrane transport
EXW42_04925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW42_04930	COG0444	Belongs to the ABC transporter superfamily
EXW42_04935	COG4608	Belongs to the ABC transporter superfamily
EXW42_04940	COG0561	phosphatase activity
EXW42_04970	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW42_04975	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW42_04985	COG0531	amino acid
EXW42_04990	COG2814	Major facilitator Superfamily
EXW42_05000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW42_05010	COG4294	response to UV
EXW42_05015	COG0705	Rhomboid family
EXW42_05020	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW42_05025	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW42_05035	COG0864	Transcriptional regulator
EXW42_05040	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW42_05045	COG2183	response to ionizing radiation
EXW42_05145	COG0802	atpase or kinase
EXW42_05150	COG1214	PFAM Peptidase M22, glycoprotease
EXW42_05155	COG0456	acetyltransferase
EXW42_05165	COG0488	(ABC) transporter
EXW42_05170	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW42_05180	COG1266	CAAX protease self-immunity
EXW42_05185	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW42_05190	COG0459	protein refolding
EXW42_05195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW42_05195	COG0519	Catalyzes the synthesis of GMP from XMP
EXW42_05200	COG2252	PERMEase
EXW42_05210	COG5002	protein histidine kinase activity
EXW42_05235	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW42_05255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW42_05260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW42_05265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW42_05270	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW42_05275	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW42_05280	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW42_05285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW42_05290	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW42_05295	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW42_05300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW42_05305	COG0138	bifunctional purine biosynthesis protein purh
EXW42_05310	COG0151	Belongs to the GarS family
EXW42_05330	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW42_05335	COG0210	DNA helicase
EXW42_05340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW42_05345	COG4851	CamS sex pheromone cAM373 precursor
EXW42_05355	COG1012	belongs to the aldehyde dehydrogenase family
EXW42_05360	COG1335	isochorismatase
EXW42_05370	COG2011	ABC-type metal ion transport system permease component
EXW42_05375	COG1464	Belongs to the NlpA lipoprotein family
EXW42_05390	COG0003	Pfam Anion-transporting ATPase
EXW42_05395	COG1846	Transcriptional regulator
EXW42_05400	COG4682	membrane
EXW42_05410	COG0154	amidase activity
EXW42_05415	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW42_05420	COG1597	lipid kinase activity
EXW42_05425	COG0546	phosphoglycolate phosphatase activity
EXW42_05430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW42_05440	COG1012	belongs to the aldehyde dehydrogenase family
EXW42_05445	COG2076	Multidrug Resistance protein
EXW42_05450	COG2309	aminopeptidase activity
EXW42_05465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW42_05475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW42_05480	COG5002	protein histidine kinase activity
EXW42_05485	COG4807	Protein conserved in bacteria
EXW42_05510	COG1757	Na H antiporter
EXW42_05515	COG1473	amidohydrolase
EXW42_05530	COG0450	alkyl hydroperoxide reductase
EXW42_05540	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW42_05550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW42_05555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW42_05560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW42_05570	COG0492	ferredoxin-NADP+ reductase activity
EXW42_05585	COG0166	Belongs to the GPI family
EXW42_05610	COG5002	protein histidine kinase activity
EXW42_05630	COG3541	Predicted nucleotidyltransferase
EXW42_05635	COG2814	Major facilitator Superfamily
EXW42_05640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW42_05640	COG0723	plastoquinol--plastocyanin reductase activity
EXW42_05650	COG0765	amino acid transport
EXW42_05655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW42_05665	COG0840	transmembrane signaling receptor activity
EXW42_05670	COG0277	FAD linked oxidase domain protein
EXW42_05675	COG0366	Alpha amylase catalytic
EXW42_05680	COG1263	PTS System
EXW42_05680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW42_05680	COG2190	(PTS) system
EXW42_05700	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW42_05705	COG0352	thiamine-phosphate diphosphorylase activity
EXW42_05710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW42_05725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW42_05730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW42_05735	COG1116	anion transmembrane transporter activity
EXW42_05740	COG0488	(ABC) transporter
EXW42_05785	COG2270	Major facilitator Superfamily
EXW42_05815	COG2310	stress, protein
EXW42_05820	COG2310	stress, protein
EXW42_05825	COG2310	stress, protein
EXW42_05830	COG0861	Integral membrane protein TerC family
EXW42_05840	COG3853	Toxic anion resistance protein (TelA)
EXW42_05850	COG4840	Belongs to the UPF0435 family
EXW42_05855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW42_05865	COG1295	ribonuclease BN
EXW42_05870	COG2217	Heavy metal translocating P-type atpase
EXW42_05875	COG0697	spore germination
EXW42_05900	COG0586	Pfam SNARE associated Golgi protein
EXW42_05915	COG3871	stress protein (general stress protein 26)
EXW42_05920	COG0387	Pfam Sodium calcium exchanger
EXW42_05930	COG0535	radical SAM domain protein
EXW42_05950	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW42_05970	COG3829	transcription factor binding
EXW42_05980	COG0833	amino acid
EXW42_05985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW42_06005	COG2066	Belongs to the glutaminase family
EXW42_06015	COG1263	PTS System
EXW42_06015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW42_06020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW42_06035	COG1216	Glycosyl transferase, family 2
EXW42_06045	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW42_06045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW42_06050	COG0463	Glycosyl transferase, family 2
EXW42_06065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW42_06070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW42_06085	COG1228	amidohydrolase
EXW42_06090	COG1090	epimerase
EXW42_06095	COG2137	regulation of response to DNA damage stimulus
EXW42_06120	COG1988	membrane-bound metal-dependent
EXW42_06125	COG1194	a g-specific adenine glycosylase
EXW42_06140	COG3557	Belongs to the UPF0374 family
EXW42_06145	COG1132	(ABC) transporter
EXW42_06150	COG4129	membrane
EXW42_06160	COG0069	glutamate synthase activity
EXW42_06160	COG0067	glutamate synthase
EXW42_06160	COG0070	glutamate synthase
EXW42_06165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW42_06170	COG4555	ABC transporter
EXW42_06190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW42_06195	COG0735	belongs to the Fur family
EXW42_06315	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW42_06320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW42_06340	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW42_06350	COG2766	serine protein kinase
EXW42_06355	COG2718	Belongs to the UPF0229 family
EXW42_06370	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW42_06375	COG2268	Band 7 protein
EXW42_06385	COG3290	protein histidine kinase activity
EXW42_06390	COG4565	transcriptional regulatory protein
EXW42_06395	COG2851	Citrate transporter
EXW42_06420	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW42_06425	COG3842	ATPase activity
EXW42_06430	COG1175	transmembrane transport
EXW42_06435	COG0395	ABC-type sugar transport system, permease component
EXW42_06445	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW42_06450	COG0745	RESPONSE REGULATOR receiver
EXW42_06455	COG5002	protein histidine kinase activity
EXW42_06465	COG4990	cell redox homeostasis
EXW42_06475	COG3290	protein histidine kinase activity
EXW42_06480	COG4565	transcriptional regulatory protein
EXW42_06485	COG3493	citrate carrier protein
EXW42_06490	COG0281	malic enzyme
EXW42_06500	COG0697	spore germination
EXW42_06505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW42_06515	COG5002	protein histidine kinase activity
EXW42_06520	COG0745	RESPONSE REGULATOR receiver
EXW42_06525	COG0456	acetyltransferase
EXW42_06530	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW42_06535	COG3383	formate dehydrogenase (NAD+) activity
EXW42_06540	COG2427	Protein of unknown function (DUF1641)
EXW42_06555	COG0531	amino acid
EXW42_06565	COG0640	Transcriptional regulator
EXW42_06570	COG2217	Heavy metal translocating P-type atpase
EXW42_06575	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW42_06590	COG3227	Zinc metalloprotease (Elastase)
EXW42_06610	COG2720	vancomycin resistance protein
EXW42_06615	COG1316	TRANSCRIPTIONal
EXW42_06620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW42_06625	COG0346	lactoylglutathione lyase activity
EXW42_06630	COG1253	flavin adenine dinucleotide binding
EXW42_06635	COG1027	Aspartate ammonia-lyase
EXW42_06640	COG1620	l-lactate permease
EXW42_06645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW42_06665	COG3104	oligopeptide transport
EXW42_06670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW42_06675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW42_06680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW42_06695	COG0156	8-amino-7-oxononanoate synthase activity
EXW42_06700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW42_06710	COG4548	von Willebrand factor, type A
EXW42_06715	COG0714	Associated with various cellular activities
EXW42_06735	COG0531	amino acid
EXW42_06740	COG2188	Transcriptional regulator
EXW42_06745	COG1263	PTS System
EXW42_06745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW42_06750	COG0366	Alpha amylase catalytic
EXW42_06765	COG0697	spore germination
EXW42_06770	COG4585	Histidine kinase
EXW42_06775	COG2197	response regulator
EXW42_06780	COG1404	Belongs to the peptidase S8 family
EXW42_06795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW42_06800	COG1115	amino acid carrier protein
EXW42_06805	COG1126	abc transporter atp-binding protein
EXW42_06810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW42_06815	COG0765	amino acid transport
EXW42_06820	COG0765	amino acid transport
EXW42_06825	COG0833	amino acid
EXW42_06850	COG2378	regulation of single-species biofilm formation
EXW42_06855	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW42_06860	COG5002	protein histidine kinase activity
EXW42_06875	COG0659	secondary active sulfate transmembrane transporter activity
EXW42_06890	COG0747	negative chemotaxis
EXW42_06900	COG0601	transmembrane transport
EXW42_06905	COG4608	Belongs to the ABC transporter superfamily
EXW42_06915	COG2271	Major facilitator Superfamily
EXW42_06920	COG1846	Transcriptional regulator
EXW42_06925	COG0477	Major facilitator Superfamily
EXW42_06930	COG1609	Transcriptional regulator
EXW42_06935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW42_06940	COG1869	D-ribose catabolic process
EXW42_06950	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW42_06955	COG1879	ABC-type sugar transport system periplasmic component
EXW42_06985	COG1063	alcohol dehydrogenase
EXW42_07000	COG3568	Endonuclease Exonuclease Phosphatase
EXW42_07030	COG0840	transmembrane signaling receptor activity
EXW42_07035	COG3583	domain protein
EXW42_07035	COG3584	3D domain protein
EXW42_07040	COG1476	TRANSCRIPTIONal
EXW42_07060	COG3104	oligopeptide transport
EXW42_07065	COG1114	Component of the transport system for branched-chain amino acids
EXW42_07080	COG1113	amino acid transport
EXW42_07085	COG2252	PERMEase
EXW42_07100	COG2153	protein acetylation
EXW42_07110	COG0569	domain protein
EXW42_07110	COG0475	glutathione-regulated potassium exporter activity
EXW42_07125	COG1845	cytochrome c oxidase, subunit III
EXW42_07130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW42_07140	COG0833	amino acid
EXW42_07145	COG4990	cell redox homeostasis
EXW42_07160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW42_07165	COG0697	spore germination
EXW42_07170	COG0531	amino acid
EXW42_07180	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW42_07185	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW42_07195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW42_07200	COG0573	inorganic phosphate transmembrane transporter activity
EXW42_07205	COG0581	inorganic phosphate transmembrane transporter activity
EXW42_07215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW42_07335	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW42_07350	COG3103	Sh3 type 3 domain protein
EXW42_07350	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW42_07350	COG4991	sh3 domain protein
EXW42_07355	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW42_07360	COG1116	anion transmembrane transporter activity
EXW42_07365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW42_07370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW42_07375	COG0352	thiamine-phosphate diphosphorylase activity
EXW42_07380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW42_07385	COG2104	thiamine diphosphate biosynthetic process
EXW42_07390	COG2022	thiamine diphosphate biosynthetic process
EXW42_07395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW42_07400	COG0351	phosphomethylpyrimidine kinase
EXW42_07425	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW42_07430	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW42_07435	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW42_07440	COG2205	protein histidine kinase activity
EXW42_07445	COG2814	Major facilitator Superfamily
EXW42_07450	COG1846	Transcriptional regulator
EXW42_07470	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW42_07475	COG1129	ABC transporter
EXW42_07480	COG1879	ABC-type sugar transport system periplasmic component
EXW42_07485	COG2252	PERMEase
EXW42_07490	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_07550	COG0778	Nitroreductase
EXW42_07555	COG2719	SpoVR family
EXW42_07580	COG1937	Protein conserved in bacteria
EXW42_07585	COG0425	Belongs to the sulfur carrier protein TusA family
EXW42_07585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW42_07590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW42_07590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW42_07595	COG0425	Belongs to the sulfur carrier protein TusA family
EXW42_07600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW42_07600	COG0425	Belongs to the sulfur carrier protein TusA family
EXW42_07605	COG2210	Belongs to the sulfur carrier protein TusA family
EXW42_07610	COG0730	response to heat
EXW42_07620	COG1316	TRANSCRIPTIONal
EXW42_07625	COG0604	alcohol dehydrogenase
EXW42_07630	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW42_07635	COG0604	alcohol dehydrogenase
EXW42_07640	COG2814	Major facilitator Superfamily
EXW42_07655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW42_07655	COG3711	transcriptional antiterminator
EXW42_07660	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW42_07665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW42_07690	COG3584	3D domain protein
EXW42_07690	COG1388	LysM domain
EXW42_07695	COG0577	efflux transmembrane transporter activity
EXW42_07700	COG1136	(ABC) transporter
EXW42_07710	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW42_07725	COG1114	Component of the transport system for branched-chain amino acids
EXW42_07730	COG3546	catalase activity
EXW42_07760	COG0586	Pfam SNARE associated Golgi protein
EXW42_07795	COG0531	amino acid
EXW42_07800	COG0475	glutathione-regulated potassium exporter activity
EXW42_07810	COG1737	Transcriptional regulator
EXW42_07815	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW42_07820	COG1263	PTS System
EXW42_07820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW42_07830	COG2259	Doxx family
EXW42_07850	COG0697	spore germination
EXW42_07855	COG1522	sequence-specific DNA binding
EXW42_07865	COG0300	oxidoreductase activity
EXW42_07880	COG2076	Multidrug Resistance protein
EXW42_07885	COG1309	transcriptional regulator
EXW42_07890	COG2814	Major facilitator Superfamily
EXW42_07895	COG1733	regulation of RNA biosynthetic process
EXW42_07910	COG4533	DNA binding
EXW42_07915	COG2211	Major facilitator Superfamily
EXW42_07925	COG0693	protein deglycase activity
EXW42_07935	COG0531	amino acid
EXW42_07940	COG1012	belongs to the aldehyde dehydrogenase family
EXW42_07955	COG1132	(ABC) transporter
EXW42_07960	COG1132	(ABC) transporter
EXW42_07965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW42_07970	COG0765	amino acid transport
EXW42_07975	COG1126	abc transporter atp-binding protein
EXW42_07990	COG0189	ligase activity
EXW42_08000	COG4399	Belongs to the UPF0754 family
EXW42_08005	COG3679	Belongs to the UPF0342 family
EXW42_08020	COG0028	Belongs to the TPP enzyme family
EXW42_08025	COG3527	Alpha-acetolactate decarboxylase
EXW42_08030	COG0463	Glycosyl transferase, family 2
EXW42_08035	COG1216	Glycosyl transferase, family 2
EXW42_08040	COG2094	Belongs to the DNA glycosylase MPG family
EXW42_08045	COG0561	phosphatase activity
EXW42_08055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW42_08060	COG0318	PFAM AMP-dependent synthetase and ligase
EXW42_08070	COG0659	secondary active sulfate transmembrane transporter activity
EXW42_08085	COG0653	protein targeting
EXW42_08090	COG2244	polysaccharide biosynthetic process
EXW42_08105	COG4196	transglutaminase domain protein
EXW42_08130	COG1024	Enoyl-CoA hydratase
EXW42_08145	COG1363	Peptidase, m42
EXW42_08160	COG2318	DinB family
EXW42_08180	COG0579	oxidoreductase
EXW42_08215	COG0601	transmembrane transport
EXW42_08220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW42_08225	COG0444	Belongs to the ABC transporter superfamily
EXW42_08230	COG4608	Belongs to the ABC transporter superfamily
EXW42_08380	COG0477	Major facilitator Superfamily
EXW42_08385	COG3290	protein histidine kinase activity
EXW42_08390	COG4565	transcriptional regulatory protein
EXW42_08395	COG3181	Tripartite tricarboxylate transporter family receptor
EXW42_08445	COG0210	DNA helicase
EXW42_08510	COG0305	Participates in initiation and elongation during chromosome replication
EXW42_08540	COG0477	Major facilitator Superfamily
EXW42_08630	COG2814	Major facilitator Superfamily
EXW42_08635	COG0640	Transcriptional regulator
EXW42_08655	COG2376	Dihydroxyacetone kinase
EXW42_08670	COG2376	Dihydroxyacetone kinase
EXW42_08690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW42_08705	COG1335	isochorismatase
EXW42_08730	COG0076	glutamate decarboxylase activity
EXW42_08755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW42_08760	COG1278	Cold shock
EXW42_08765	COG1309	transcriptional regulator
EXW42_08785	COG3237	CsbD-like
EXW42_08805	COG2172	sigma factor antagonist activity
EXW42_08810	COG1191	sigma factor activity
EXW42_08820	COG2208	phosphoserine phosphatase activity
EXW42_08825	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW42_08870	COG2807	transmembrane transport
EXW42_08875	COG2186	Transcriptional regulator
EXW42_08890	COG4585	Histidine kinase
EXW42_08895	COG2197	response regulator
EXW42_08925	COG0420	3'-5' exonuclease activity
EXW42_08930	COG4717	serine-type aminopeptidase activity
EXW42_08935	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW42_08945	COG0346	lactoylglutathione lyase activity
EXW42_08950	COG0457	Tetratricopeptide repeat
EXW42_08960	COG2267	carboxylic ester hydrolase activity
EXW42_08975	COG3620	sequence-specific DNA binding
EXW42_08980	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW42_08985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW42_08990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW42_08995	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW42_09000	COG1695	Transcriptional regulator
EXW42_09010	COG1595	DNA-templated transcription, initiation
EXW42_09025	COG3973	AAA domain
EXW42_09030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW42_09045	COG1846	Transcriptional regulator
EXW42_09055	COG0537	adenosine 5'-monophosphoramidase activity
EXW42_09060	COG1131	(ABC) transporter
EXW42_09065	COG4473	ABC transporter
EXW42_09075	COG0247	lactate metabolic process
EXW42_09080	COG1139	Iron-sulfur cluster binding protein
EXW42_09085	COG1556	Lactate utilization protein
EXW42_09100	COG3402	PFAM membrane-flanked domain
EXW42_09105	COG3428	Bacterial PH domain
EXW42_09145	COG3402	PFAM membrane-flanked domain
EXW42_09150	COG3428	Bacterial PH domain
EXW42_09155	COG2329	Antibiotic biosynthesis monooxygenase
EXW42_09160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW42_09165	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW42_09170	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW42_09175	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW42_09195	COG1309	transcriptional regulator
EXW42_09200	COG1511	domain protein
EXW42_09235	COG2378	regulation of single-species biofilm formation
EXW42_09240	COG1609	Transcriptional regulator
EXW42_09250	COG1234	tRNA 3'-trailer cleavage
EXW42_09255	COG0095	Lipoate-protein ligase
EXW42_09265	COG0318	PFAM AMP-dependent synthetase and ligase
EXW42_09280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW42_09285	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW42_09290	COG4208	sulfate ABC transporter
EXW42_09305	COG1408	metallophosphoesterase
EXW42_09310	COG1078	dGTPase activity
EXW42_09325	COG1595	DNA-templated transcription, initiation
EXW42_09335	COG3708	Transcriptional regulator
EXW42_09335	COG2207	Transcriptional regulator
EXW42_09340	COG2205	protein histidine kinase activity
EXW42_09345	COG0745	RESPONSE REGULATOR receiver
EXW42_09365	COG0501	Belongs to the peptidase M48B family
EXW42_09370	COG0697	spore germination
EXW42_09400	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW42_09405	COG2224	Isocitrate lyase
EXW42_09415	COG1278	Cold shock
EXW42_09435	COG4903	ComK protein
EXW42_09440	COG0398	Pfam SNARE associated Golgi protein
EXW42_09450	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW42_09455	COG1074	ATP-dependent DNA helicase activity
EXW42_09505	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW42_09530	COG0367	asparagine synthase
EXW42_09540	COG0753	catalase activity
EXW42_09545	COG0004	ammonium transporteR
EXW42_09555	COG1666	GTP binding
EXW42_09560	COG2996	Protein conserved in bacteria
EXW42_09565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW42_09575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW42_09590	COG0561	phosphatase activity
EXW42_09610	COG2267	carboxylic ester hydrolase activity
EXW42_09625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW42_09630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW42_09635	COG5504	Zn-dependent protease
EXW42_09650	COG0180	Tryptophanyl-tRNA synthetase
EXW42_09665	COG4166	transmembrane transport
EXW42_09670	COG0601	transmembrane transport
EXW42_09675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW42_09680	COG0444	Belongs to the ABC transporter superfamily
EXW42_09685	COG4608	Belongs to the ABC transporter superfamily
EXW42_09690	COG0534	Mate efflux family protein
EXW42_09695	COG4166	transmembrane transport
EXW42_09715	COG0861	Integral membrane protein TerC family
EXW42_09720	COG4862	establishment of competence for transformation
EXW42_09725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW42_09735	COG1164	Oligoendopeptidase f
EXW42_09745	COG2346	COG2346, Truncated hemoglobins
EXW42_09750	COG4116	CYTH
EXW42_09760	COG2357	RelA SpoT domain protein
EXW42_09770	COG0564	pseudouridine synthase activity
EXW42_09780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW42_09785	COG0772	Belongs to the SEDS family
EXW42_09790	COG1216	Glycosyl transferase, family 2
EXW42_09810	COG0457	Tetratricopeptide repeat
EXW42_09810	COG0463	Glycosyl transferase, family 2
EXW42_09830	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW42_09845	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW42_09890	COG2153	protein acetylation
EXW42_09895	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW42_09900	COG2382	esterase
EXW42_09925	COG5492	domain, Protein
EXW42_09930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW42_09945	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW42_09945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW42_09950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW42_09955	COG0134	indole-3-glycerol-phosphate synthase activity
EXW42_09960	COG0135	phosphoribosylanthranilate isomerase activity
EXW42_09965	COG0133	tryptophan synthase activity
EXW42_09970	COG0159	tryptophan synthase activity
EXW42_09980	COG1620	l-lactate permease
EXW42_09985	COG5634	Uncharacterized conserved protein (DUF2278)
EXW42_10045	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW42_10050	COG0567	Dehydrogenase, E1 component
EXW42_10055	COG1476	TRANSCRIPTIONal
EXW42_10165	COG0582	viral genome integration into host DNA
EXW42_10185	COG1686	Belongs to the peptidase S11 family
EXW42_10190	COG0681	Belongs to the peptidase S26 family
EXW42_10225	COG1012	belongs to the aldehyde dehydrogenase family
EXW42_10235	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW42_10240	COG1177	transmembrane transport
EXW42_10245	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW42_10255	COG2409	Drug exporters of the RND superfamily
EXW42_10265	COG0564	pseudouridine synthase activity
EXW42_10275	COG2340	Cysteine-rich secretory protein family
EXW42_10280	COG0247	lactate metabolic process
EXW42_10285	COG0277	FAD linked oxidase domain protein
EXW42_10290	COG3835	regulator
EXW42_10300	COG0745	RESPONSE REGULATOR receiver
EXW42_10305	COG5002	protein histidine kinase activity
EXW42_10310	COG2186	Transcriptional regulator
EXW42_10315	COG0247	lactate metabolic process
EXW42_10320	COG1139	Iron-sulfur cluster binding protein
EXW42_10325	COG1556	Lactate utilization protein
EXW42_10330	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW42_10340	COG2116	formate transmembrane transporter activity
EXW42_10345	COG0861	Integral membrane protein TerC family
EXW42_10350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW42_10360	COG2030	dehydratase
EXW42_10380	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_10385	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW42_10395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW42_10410	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW42_10415	COG3842	ATPase activity
EXW42_10425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW42_10430	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW42_10440	COG1349	DNA-binding transcription factor activity
EXW42_10450	COG0235	Class ii aldolase
EXW42_10460	COG2861	carbohydrate metabolic process
EXW42_10470	COG3852	Histidine kinase
EXW42_10475	COG1846	Transcriptional regulator
EXW42_10485	COG2318	DinB family
EXW42_10490	COG5002	protein histidine kinase activity
EXW42_10495	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW42_10500	COG0720	synthase
EXW42_10510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW42_10515	COG4873	Protein conserved in bacteria
EXW42_10525	COG0456	acetyltransferase
EXW42_10545	COG1780	Probably involved in ribonucleotide reductase function
EXW42_10560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW42_10565	COG0531	amino acid
EXW42_10570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW42_10585	COG2204	response regulator
EXW42_10590	COG1012	belongs to the aldehyde dehydrogenase family
EXW42_10600	COG1725	Transcriptional regulator
EXW42_10605	COG1131	(ABC) transporter
EXW42_10615	COG1131	(ABC) transporter
EXW42_10620	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW42_10625	COG1266	CAAX protease self-immunity
EXW42_10635	COG1522	sequence-specific DNA binding
EXW42_10645	COG1335	isochorismatase
EXW42_10655	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW42_10660	COG2070	2-Nitropropane dioxygenase
EXW42_10665	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW42_10670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW42_10675	COG1696	Membrane protein involved in D-alanine export
EXW42_10695	COG0716	FMN binding
EXW42_10720	COG0534	Mate efflux family protein
EXW42_10725	COG1968	undecaprenyl-diphosphatase activity
EXW42_10745	COG1846	Transcriptional regulator
EXW42_10755	COG1301	dicarboxylic acid transport
EXW42_10760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW42_10770	COG3874	Sporulation protein YtfJ
EXW42_10790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW42_10795	COG0028	Belongs to the TPP enzyme family
EXW42_10800	COG0440	acetolactate synthase activity
EXW42_10810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW42_10820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW42_10830	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW42_10835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW42_10845	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW42_10850	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW42_10855	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW42_10860	COG0107	imidazoleglycerol-phosphate synthase activity
EXW42_10870	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW42_10875	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW42_10890	COG1183	phosphatidylcholine synthase activity
EXW42_10895	COG1368	sulfuric ester hydrolase activity
EXW42_10905	COG0019	diaminopimelate decarboxylase activity
EXW42_10915	COG0175	sulfate reduction
EXW42_10920	COG2046	Belongs to the sulfate adenylyltransferase family
EXW42_10925	COG0529	Catalyzes the synthesis of activated sulfate
EXW42_10930	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW42_10950	COG1648	precorrin-2 dehydrogenase activity
EXW42_10960	COG0733	neurotransmitter:sodium symporter activity
EXW42_10980	COG1757	Na H antiporter
EXW42_10995	COG4758	membrane
EXW42_11000	COG4585	Histidine kinase
EXW42_11005	COG2197	response regulator
EXW42_11015	COG1114	Component of the transport system for branched-chain amino acids
EXW42_11025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW42_11070	COG0730	response to heat
EXW42_11075	COG0306	phosphate transporter
EXW42_11080	COG1392	Phosphate transport regulator
EXW42_11085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW42_11100	COG3852	Histidine kinase
EXW42_11105	COG1801	Protein of unknown function DUF72
EXW42_11115	COG0582	viral genome integration into host DNA
EXW42_11120	COG5002	protein histidine kinase activity
EXW42_11135	COG0392	lysyltransferase activity
EXW42_11135	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW42_11150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW42_11155	COG1686	Belongs to the peptidase S11 family
EXW42_11160	COG2715	membrane protein required for spore maturation
EXW42_11165	COG0700	Nucleoside recognition
EXW42_11170	COG1187	pseudouridine synthase activity
EXW42_11180	COG1333	cytochrome c biogenesis protein
EXW42_11185	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW42_11190	COG0745	RESPONSE REGULATOR receiver
EXW42_11195	COG5002	protein histidine kinase activity
EXW42_11200	COG2096	Adenosyltransferase
EXW42_11205	COG4942	peptidase
EXW42_11215	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW42_11220	COG1141	Ferredoxin
EXW42_11230	COG4955	Helix-turn-helix domain
EXW42_11235	COG0514	ATP-dependent DNA helicase (RecQ)
EXW42_11240	COG1266	CAAX protease self-immunity
EXW42_11250	COG1408	metallophosphoesterase
EXW42_11265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW42_11285	COG0492	ferredoxin-NADP+ reductase activity
EXW42_11290	COG0252	asparaginase activity
EXW42_11295	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW42_11305	COG1304	FMN binding
EXW42_11340	COG1160	GTP binding
EXW42_11345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW42_11365	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW42_11375	COG0302	gtp cyclohydrolase
EXW42_11380	COG0142	geranyltranstransferase activity
EXW42_11385	COG2226	methyltransferase
EXW42_11390	COG0142	geranyltranstransferase activity
EXW42_11405	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW42_11415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW42_11420	COG0457	Tetratricopeptide repeat
EXW42_11425	COG5582	Belongs to the UPF0302 family
EXW42_11440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW42_11460	COG4347	Protein of unknown function (DUF1405)
EXW42_11475	COG2738	Putative neutral zinc metallopeptidase
EXW42_11485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW42_11495	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW42_11500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW42_11505	COG1803	Methylglyoxal synthase
EXW42_11510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW42_11515	COG0438	transferase activity, transferring glycosyl groups
EXW42_11520	COG0617	tRNA 3'-terminal CCA addition
EXW42_11530	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW42_11535	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW42_11545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW42_11545	COG1199	ATP-dependent helicase activity
EXW42_11565	COG3935	DnaD domain protein
EXW42_11570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW42_11580	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW42_11580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW42_11585	COG3331	DNA recombination
EXW42_11620	COG4474	Belongs to the UPF0398 family
EXW42_11625	COG3599	regulation of cell shape
EXW42_11635	COG0116	Belongs to the methyltransferase superfamily
EXW42_11645	COG1199	ATP-dependent helicase activity
EXW42_11650	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW42_11660	COG0024	Methionine aminopeptidase
EXW42_11665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW42_11670	COG2233	PERMEase
EXW42_11675	COG2311	Membrane
EXW42_11680	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW42_11690	COG0456	acetyltransferase
EXW42_11700	COG2897	thiosulfate sulfurtransferase activity
EXW42_11740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW42_11755	COG0454	-acetyltransferase
EXW42_11775	COG0328	RNA-DNA hybrid ribonuclease activity
EXW42_11810	COG3403	YqcI/YcgG family
EXW42_11815	COG1280	lysine exporter protein (LysE YggA)
EXW42_11830	COG3162	membrane
EXW42_11835	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW42_11840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW42_11850	COG0475	glutathione-regulated potassium exporter activity
EXW42_11855	COG0789	Transcriptional regulator
EXW42_11855	COG4978	Transcriptional regulator
EXW42_11865	COG2323	membrane
EXW42_11870	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW42_11900	COG2814	Major facilitator Superfamily
EXW42_11920	COG1923	regulation of RNA biosynthetic process
EXW42_11930	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW42_11935	COG1360	Flagellar Motor Protein
EXW42_11940	COG2201	protein-glutamate methylesterase activity
EXW42_11945	COG0643	Histidine kinase
EXW42_11945	COG2198	Histidine kinase
EXW42_11950	COG1776	CheC inhibitor of MCP methylation
EXW42_11950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW42_11965	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW42_11985	COG1256	bacterial-type flagellum assembly
EXW42_11990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW42_12015	COG1815	bacterial-type flagellum-dependent cell motility
EXW42_12020	COG1558	bacterial-type flagellum-dependent cell motility
EXW42_12030	COG1766	The M ring may be actively involved in energy transduction
EXW42_12035	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW42_12045	COG1157	protein secretion by the type III secretion system
EXW42_12065	COG1749	Flagellar hook protein flgE
EXW42_12080	COG0835	chemotaxis
EXW42_12080	COG0784	Response regulator, receiver
EXW42_12105	COG0861	Integral membrane protein TerC family
EXW42_12115	COG3383	formate dehydrogenase (NAD+) activity
EXW42_12120	COG2427	Protein of unknown function (DUF1641)
EXW42_12125	COG5609	conserved protein (DUF2294)
EXW42_12130	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW42_12140	COG2116	formate transmembrane transporter activity
EXW42_12145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW42_12150	COG0303	'Molybdopterin
EXW42_12155	COG0314	molybdopterin synthase activity
EXW42_12160	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW42_12170	COG0489	protein tyrosine kinase activity
EXW42_12185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW42_12190	COG0741	lytic transglycosylase activity
EXW42_12200	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW42_12205	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW42_12205	COG1776	CheC inhibitor of MCP methylation
EXW42_12215	COG1338	Plays a role in the flagellum-specific transport system
EXW42_12220	COG1987	bacterial-type flagellum assembly
EXW42_12230	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW42_12235	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW42_12240	COG1419	protein localization to endoplasmic reticulum
EXW42_12245	COG4786	Flagellar basal body rod
EXW42_12250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW42_12280	COG0412	Dienelactone hydrolase
EXW42_12285	COG2329	Antibiotic biosynthesis monooxygenase
EXW42_12300	COG2814	Major facilitator Superfamily
EXW42_12310	COG0583	DNA-binding transcription factor activity
EXW42_12315	COG3842	ATPase activity
EXW42_12360	COG1686	Belongs to the peptidase S11 family
EXW42_12365	COG0406	alpha-ribazole phosphatase activity
EXW42_12395	COG0367	asparagine synthase
EXW42_12425	COG1802	Transcriptional regulator
EXW42_12430	COG0697	spore germination
EXW42_12445	COG1216	Glycosyl transferase, family 2
EXW42_12445	COG0438	transferase activity, transferring glycosyl groups
EXW42_12450	COG1757	Na H antiporter
EXW42_12460	COG0277	FAD linked oxidase domain protein
EXW42_12480	COG0534	Mate efflux family protein
EXW42_12485	COG3340	Belongs to the peptidase S51 family
EXW42_12505	COG0785	Cytochrome C biogenesis protein
EXW42_12510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW42_12525	COG3048	D-serine ammonia-lyase activity
EXW42_12530	COG2733	membrane
EXW42_12570	COG1131	(ABC) transporter
EXW42_12585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW42_12620	COG0528	UMP kinase activity
EXW42_12630	COG1027	Aspartate ammonia-lyase
EXW42_12635	COG0281	malic enzyme
EXW42_12640	COG4191	Histidine kinase
EXW42_12645	COG0784	Response regulator, receiver
EXW42_12650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW42_12665	COG2502	aspartate--ammonia ligase
EXW42_12720	COG2816	NAD+ diphosphatase activity
EXW42_12735	COG2814	Major facilitator Superfamily
EXW42_12765	COG0477	Major facilitator Superfamily
EXW42_12770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW42_12780	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW42_12785	COG2223	nitrite transmembrane transporter activity
EXW42_12790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW42_12800	COG2244	polysaccharide biosynthetic process
EXW42_12805	COG0733	neurotransmitter:sodium symporter activity
EXW42_12815	COG5566	PFAM Mor transcription activator
EXW42_12820	COG2323	membrane
EXW42_12835	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW42_12845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW42_12850	COG0028	Belongs to the TPP enzyme family
EXW42_12865	COG0129	dihydroxy-acid dehydratase activity
EXW42_12870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW42_12895	COG2814	Major facilitator Superfamily
EXW42_12900	COG3384	dioxygenase
EXW42_12940	COG4166	transmembrane transport
EXW42_12975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW42_12995	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW42_13000	COG1054	Belongs to the UPF0176 family
EXW42_13010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW42_13015	COG0531	amino acid
EXW42_13050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW42_13065	COG4257	antibiotic catabolic process
EXW42_13070	COG2390	Transcriptional regulator
EXW42_13080	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW42_13085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW42_13090	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW42_13105	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW42_13120	COG0583	DNA-binding transcription factor activity
EXW42_13140	COG0006	proline dipeptidase activity
EXW42_13145	COG2132	Multicopper oxidase
EXW42_13160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW42_13170	COG0583	DNA-binding transcription factor activity
EXW42_13190	COG1114	Component of the transport system for branched-chain amino acids
EXW42_13200	COG4641	Protein conserved in bacteria
EXW42_13215	COG1276	copper resistance
EXW42_13215	COG2372	response to copper ion
EXW42_13220	COG4549	nuclear export factor GLE1
EXW42_13230	COG0697	spore germination
EXW42_13235	COG0583	DNA-binding transcription factor activity
EXW42_13240	COG1959	2 iron, 2 sulfur cluster binding
EXW42_13245	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW42_13250	COG0778	Nitroreductase
EXW42_13260	COG0628	permease
EXW42_13275	COG1231	oxidoreductase activity
EXW42_13280	COG0523	cobalamin synthesis protein
EXW42_13290	COG0318	PFAM AMP-dependent synthetase and ligase
EXW42_13295	COG2030	dehydratase
EXW42_13300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW42_13315	COG0411	ABC transporter
EXW42_13335	COG0583	DNA-binding transcription factor activity
EXW42_13345	COG1942	4-Oxalocrotonate Tautomerase
EXW42_13360	COG0346	lactoylglutathione lyase activity
EXW42_13370	COG1271	oxidase subunit
EXW42_13375	COG1294	oxidase, subunit
EXW42_13380	COG4988	ABC transporter
EXW42_13385	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW42_13415	COG1686	Belongs to the peptidase S11 family
EXW42_13430	COG0791	NLP P60 protein
EXW42_13430	COG1388	LysM domain
EXW42_13440	COG1132	(ABC) transporter
EXW42_13445	COG0745	RESPONSE REGULATOR receiver
EXW42_13450	COG5002	protein histidine kinase activity
EXW42_13455	COG0300	oxidoreductase activity
EXW42_13460	COG4122	O-methyltransferase activity
EXW42_13480	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EXW42_13490	COG0460	homoserine dehydrogenase
EXW42_13500	COG0083	homoserine kinase activity
EXW42_13515	COG1316	TRANSCRIPTIONal
EXW42_13540	COG1285	pathogenesis
EXW42_13545	COG1247	-acetyltransferase
EXW42_13565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW42_13575	COG1082	Xylose isomerase domain protein TIM barrel
EXW42_13585	COG2814	Major facilitator Superfamily
EXW42_13590	COG1279	arginine transmembrane transporter activity
EXW42_13595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW42_13605	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW42_13635	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW42_13640	COG0577	efflux transmembrane transporter activity
EXW42_13645	COG2002	toxin-antitoxin pair type II binding
EXW42_13650	COG1404	Belongs to the peptidase S8 family
EXW42_13655	COG0640	Transcriptional regulator
EXW42_13660	COG0667	Aldo Keto reductase
EXW42_13665	COG2814	Major facilitator Superfamily
EXW42_13710	COG3949	Membrane
EXW42_13715	COG0783	Belongs to the Dps family
EXW42_13730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW42_13740	COG1231	oxidoreductase activity
EXW42_13745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW42_13750	COG4989	oxidoreductase activity
EXW42_13755	COG0523	cobalamin synthesis protein
EXW42_13760	COG0456	acetyltransferase
EXW42_13765	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW42_13785	COG2814	Major facilitator Superfamily
EXW42_13790	COG1136	(ABC) transporter
EXW42_13795	COG0577	efflux transmembrane transporter activity
EXW42_13800	COG0745	RESPONSE REGULATOR receiver
EXW42_13805	COG2205	protein histidine kinase activity
EXW42_13810	COG1902	pentaerythritol trinitrate reductase activity
EXW42_13815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW42_13825	COG4166	transmembrane transport
EXW42_13830	COG0346	lactoylglutathione lyase activity
EXW42_13840	COG0406	alpha-ribazole phosphatase activity
EXW42_13850	COG5337	Spore coat protein CotH
EXW42_13855	COG1051	belongs to the nudix hydrolase family
EXW42_13860	COG0586	Pfam SNARE associated Golgi protein
EXW42_13865	COG2244	polysaccharide biosynthetic process
EXW42_13875	COG0701	Predicted permease
EXW42_13880	COG3689	TIGRFAM TIGR03943 family protein
EXW42_13885	COG1607	acyl-coa hydrolase
EXW42_13895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW42_13915	COG0702	epimerase
EXW42_13920	COG2839	Protein conserved in bacteria
EXW42_13925	COG1253	flavin adenine dinucleotide binding
EXW42_13940	COG1114	Component of the transport system for branched-chain amino acids
EXW42_13945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW42_13965	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW42_13980	COG1876	peptidase activity
EXW42_13990	COG2211	Major facilitator Superfamily
EXW42_14005	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW42_14015	COG0561	phosphatase activity
EXW42_14025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW42_14045	COG1819	glycosyl
EXW42_14050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW42_14055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW42_14080	COG0456	acetyltransferase
EXW42_14115	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW42_14285	COG4974	Belongs to the 'phage' integrase family
EXW42_14295	COG3874	Sporulation protein YtfJ
EXW42_14320	COG2226	methyltransferase
EXW42_14350	COG0604	alcohol dehydrogenase
EXW42_14355	COG1595	DNA-templated transcription, initiation
EXW42_14390	COG0386	Belongs to the glutathione peroxidase family
EXW42_14395	COG1305	Transglutaminase-like
EXW42_14400	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW42_14405	COG0714	Associated with various cellular activities
EXW42_14410	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW42_14415	COG1140	nitrate reductase beta subunit
EXW42_14420	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW42_14425	COG2181	nitrate reductase activity
EXW42_14430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW42_14435	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW42_14440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW42_14445	COG0303	'Molybdopterin
EXW42_14450	COG0314	molybdopterin synthase activity
EXW42_14460	COG2223	nitrite transmembrane transporter activity
EXW42_14480	COG1648	precorrin-2 dehydrogenase activity
EXW42_14490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW42_14490	COG1587	Uroporphyrinogen-III synthase
EXW42_14495	COG2146	nitrite reductase [NAD(P)H] activity
EXW42_14500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW42_14505	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW42_14535	COG2359	stage V sporulation protein S
EXW42_14595	COG0582	viral genome integration into host DNA
EXW42_14600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW42_14625	COG1418	mRNA catabolic process
EXW42_14630	COG0488	(ABC) transporter
EXW42_14650	COG1413	lyase activity
EXW42_14665	COG2521	methyltransferase
EXW42_14665	COG2136	Putative SAM-dependent methyltransferase
EXW42_14730	COG0017	Asparaginyl-tRNA synthetase
EXW42_14735	COG0733	neurotransmitter:sodium symporter activity
EXW42_14760	COG2610	gluconate transmembrane transporter activity
EXW42_14770	COG1794	racemase activity, acting on amino acids and derivatives
EXW42_14780	COG0456	acetyltransferase
EXW42_14785	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW42_14795	COG1131	(ABC) transporter
EXW42_14800	COG4473	ABC transporter
EXW42_14810	COG0546	phosphoglycolate phosphatase activity
EXW42_14825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW42_14840	COG0768	penicillin binding
EXW42_14850	COG0204	Acyl-transferase
EXW42_14855	COG1272	protein, Hemolysin III
EXW42_14860	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW42_14865	COG0805	protein transport
EXW42_14880	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW42_14885	COG1999	signal sequence binding
EXW42_14890	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW42_14895	COG0367	asparagine synthase
EXW42_14910	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW42_14915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW42_14920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW42_14940	COG1335	isochorismatase
EXW42_14950	COG0668	transmembrane transport
EXW42_14955	COG2203	Gaf domain
EXW42_14955	COG4585	Histidine kinase
EXW42_14960	COG2197	response regulator
EXW42_14965	COG1737	Transcriptional regulator
EXW42_14970	COG1064	alcohol dehydrogenase
EXW42_14985	COG1070	Carbohydrate kinase
EXW42_14995	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW42_15015	COG0517	IMP dehydrogenase activity
EXW42_15015	COG1125	glycine betaine transport
EXW42_15020	COG1174	glycine betaine transport
EXW42_15055	COG1253	flavin adenine dinucleotide binding
EXW42_15060	COG1012	belongs to the aldehyde dehydrogenase family
EXW42_15065	COG5506	Protein of unknown function (DUF1694)
EXW42_15080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW42_15085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW42_15090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW42_15095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW42_15100	COG0456	acetyltransferase
EXW42_15105	COG3829	transcription factor binding
EXW42_15110	COG1509	lysine 2,3-aminomutase activity
EXW42_15120	COG4479	Belongs to the UPF0346 family
EXW42_15145	COG3064	Membrane
EXW42_15145	COG0515	serine threonine protein kinase
EXW42_15145	COG4991	sh3 domain protein
EXW42_15155	COG0671	phosphoesterase, PA-phosphatase related
EXW42_15160	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW42_15165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW42_15220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW42_15250	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_15270	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW42_15270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW42_15280	COG2814	Major facilitator Superfamily
EXW42_15290	COG0372	Belongs to the citrate synthase family
EXW42_15295	COG2079	MmgE PrpD family protein
EXW42_15300	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW42_15305	COG1960	acyl-CoA dehydrogenase activity
EXW42_15310	COG2084	Dehydrogenase
EXW42_15315	COG1012	belongs to the aldehyde dehydrogenase family
EXW42_15320	COG1280	lysine exporter protein (LysE YggA)
EXW42_15325	COG1024	Enoyl-CoA hydratase
EXW42_15340	COG0420	3'-5' exonuclease activity
EXW42_15360	COG2223	nitrite transmembrane transporter activity
EXW42_15365	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_15370	COG1169	isochorismate synthase
EXW42_15375	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW42_15380	COG1535	isochorismatase
EXW42_15380	COG3433	isochorismatase activity
EXW42_15385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW42_15390	COG3251	PFAM MbtH domain protein
EXW42_15395	COG2814	Major facilitator Superfamily
EXW42_15410	COG0776	regulation of translation
EXW42_15420	COG2318	DinB family
EXW42_15425	COG1115	amino acid carrier protein
EXW42_15440	COG2329	Antibiotic biosynthesis monooxygenase
EXW42_15455	COG1187	pseudouridine synthase activity
EXW42_15460	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW42_15465	COG3655	Transcriptional regulator
EXW42_15475	COG1136	(ABC) transporter
EXW42_15485	COG0596	Alpha beta hydrolase
EXW42_15500	COG0028	Belongs to the TPP enzyme family
EXW42_15525	COG1253	flavin adenine dinucleotide binding
EXW42_15555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW42_15575	COG1846	Transcriptional regulator
EXW42_15585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW42_15590	COG1309	transcriptional regulator
EXW42_15620	COG1247	-acetyltransferase
EXW42_15660	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW42_15670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW42_15700	COG0583	DNA-binding transcription factor activity
EXW42_15705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW42_15720	COG0583	DNA-binding transcription factor activity
EXW42_15725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW42_15730	COG2258	MOSC domain
EXW42_15745	COG1132	(ABC) transporter
EXW42_15750	COG1132	(ABC) transporter
EXW42_15765	COG0189	ligase activity
EXW42_15790	COG1396	sequence-specific DNA binding
EXW42_15825	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW42_15830	COG1595	DNA-templated transcription, initiation
EXW42_15930	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW42_15935	COG2971	BadF BadG BcrA BcrD
EXW42_15945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW42_15995	COG1309	transcriptional regulator
EXW42_16010	COG1136	(ABC) transporter
EXW42_16010	COG0577	efflux transmembrane transporter activity
EXW42_16015	COG0500	methyltransferase
EXW42_16015	COG3615	Tellurite resistance protein tehB
EXW42_16025	COG0693	protein deglycase activity
EXW42_16035	COG0588	phosphoglycerate mutase activity
EXW42_16055	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW42_16060	COG0110	maltose O-acetyltransferase activity
EXW42_16075	COG1136	(ABC) transporter
EXW42_16105	COG1686	Belongs to the peptidase S11 family
EXW42_16130	COG0768	penicillin binding
EXW42_16135	COG0745	RESPONSE REGULATOR receiver
EXW42_16140	COG2205	protein histidine kinase activity
EXW42_16145	COG1136	(ABC) transporter
EXW42_16150	COG0577	efflux transmembrane transporter activity
EXW42_16160	COG1595	DNA-templated transcription, initiation
EXW42_16170	COG0768	penicillin binding
EXW42_16175	COG0768	penicillin binding
EXW42_16195	COG1252	NADH dehydrogenase
EXW42_16200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW42_16200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW42_16225	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW42_16225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW42_16250	COG1136	(ABC) transporter
EXW42_16255	COG0577	efflux transmembrane transporter activity
EXW42_16275	COG1136	(ABC) transporter
EXW42_16295	COG2723	6-phospho-beta-galactosidase activity
EXW42_16375	COG1114	Component of the transport system for branched-chain amino acids
EXW42_16385	COG2239	Acts as a magnesium transporter
EXW42_16420	COG0697	spore germination
EXW42_16445	COG3397	chitin binding
EXW42_16450	COG0823	Involved in the tonB-independent uptake of proteins
EXW42_16460	COG1408	metallophosphoesterase
EXW42_16470	COG1131	(ABC) transporter
EXW42_16480	COG1309	transcriptional regulator
EXW42_16490	COG1960	acyl-CoA dehydrogenase activity
EXW42_16495	COG0439	Biotin carboxylase
EXW42_16500	COG0511	ligase activity, forming carbon-carbon bonds
EXW42_16505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW42_16510	COG1024	Enoyl-CoA hydratase
EXW42_16515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW42_16520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW42_16535	COG3344	reverse transcriptase
EXW42_16565	COG0572	uridine kinase
EXW42_16570	COG2318	DinB family
EXW42_16600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW42_16630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW42_16655	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_16660	COG1733	regulation of RNA biosynthetic process
EXW42_16685	COG1309	transcriptional regulator
EXW42_16715	COG0697	spore germination
EXW42_16720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW42_16750	COG2323	membrane
EXW42_16765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW42_16770	COG0697	spore germination
EXW42_16790	COG0201	protein transport
EXW42_16800	COG0737	Belongs to the 5'-nucleotidase family
EXW42_16805	COG3227	Zinc metalloprotease (Elastase)
EXW42_16810	COG1523	belongs to the glycosyl hydrolase 13 family
EXW42_16825	COG0076	glutamate decarboxylase activity
EXW42_16830	COG0657	acetylesterase activity
EXW42_16840	COG1073	alpha beta
EXW42_16850	COG0577	efflux transmembrane transporter activity
EXW42_16855	COG1136	(ABC) transporter
EXW42_16870	COG5002	protein histidine kinase activity
EXW42_16875	COG0745	RESPONSE REGULATOR receiver
EXW42_16880	COG1011	Hydrolase
EXW42_16905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW42_16910	COG1183	phosphatidylcholine synthase activity
EXW42_16925	COG1132	(ABC) transporter
EXW42_16935	COG3961	Belongs to the TPP enzyme family
EXW42_16955	COG0322	excinuclease ABC activity
EXW42_16980	COG2318	DinB family
EXW42_16995	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW42_17020	COG3878	Protein conserved in bacteria
EXW42_17045	COG1051	belongs to the nudix hydrolase family
EXW42_17050	COG0592	DNA-directed DNA polymerase activity
EXW42_17055	COG2816	NAD+ diphosphatase activity
EXW42_17065	COG2223	nitrite transmembrane transporter activity
EXW42_17070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW42_17080	COG0494	nUDIX hydrolase
EXW42_17100	COG0697	spore germination
EXW42_17105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW42_17120	COG0584	glycerophosphoryl diester phosphodiesterase
EXW42_17135	COG2814	Major facilitator Superfamily
EXW42_17175	COG0768	penicillin binding
EXW42_17180	COG0671	phosphoesterase, PA-phosphatase related
EXW42_17185	COG0604	alcohol dehydrogenase
EXW42_17190	COG5002	protein histidine kinase activity
EXW42_17195	COG0745	RESPONSE REGULATOR receiver
EXW42_17205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW42_17215	COG2205	protein histidine kinase activity
EXW42_17230	COG1122	ATPase activity
EXW42_17235	COG4720	Psort location CytoplasmicMembrane, score
EXW42_17240	COG1794	racemase activity, acting on amino acids and derivatives
EXW42_17245	COG1819	glycosyl
EXW42_17255	COG0768	penicillin binding
EXW42_17260	COG5002	protein histidine kinase activity
EXW42_17265	COG0561	phosphatase activity
EXW42_17315	COG2124	cytochrome p450
EXW42_17445	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW42_17455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW42_17460	COG0460	homoserine dehydrogenase
EXW42_17480	COG0577	efflux transmembrane transporter activity
EXW42_17485	COG1136	(ABC) transporter
EXW42_17495	COG0488	(ABC) transporter
EXW42_17500	COG0667	Aldo Keto reductase
EXW42_17505	COG0583	DNA-binding transcription factor activity
EXW42_17515	COG0745	RESPONSE REGULATOR receiver
EXW42_17530	COG3773	Cell wall hydrolase
EXW42_17535	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW42_17585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW42_17600	COG2959	enzyme of heme biosynthesis
EXW42_17630	COG3483	tryptophan 2,3-dioxygenase activity
EXW42_17635	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW42_17640	COG3844	kynureninase activity
EXW42_17645	COG1309	transcriptional regulator
EXW42_17660	COG3284	Transcriptional regulator
EXW42_17675	COG1349	DNA-binding transcription factor activity
EXW42_17695	COG1959	2 iron, 2 sulfur cluster binding
EXW42_17710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW42_17715	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW42_17720	COG0022	dehydrogenase e1 component
EXW42_17725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW42_17740	COG2207	Transcriptional regulator
EXW42_17745	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_17750	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW42_17750	COG0456	acetyltransferase
EXW42_17785	COG4176	ABC-type proline glycine betaine transport system permease component
EXW42_17790	COG0517	IMP dehydrogenase activity
EXW42_17790	COG4175	Glycine betaine
EXW42_17815	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW42_17820	COG2153	protein acetylation
EXW42_17825	COG3397	chitin binding
EXW42_17835	COG1819	glycosyl
EXW42_17850	COG2205	protein histidine kinase activity
EXW42_17855	COG2315	Protein conserved in bacteria
EXW42_17910	COG3973	AAA domain
EXW42_17920	COG2105	PFAM AIG2 family protein
EXW42_17925	COG0514	ATP-dependent DNA helicase (RecQ)
EXW42_17945	COG4637	Psort location Cytoplasmic, score
EXW42_17955	COG1227	inorganic diphosphatase activity
EXW42_17960	COG3397	chitin binding
EXW42_17965	COG2318	DinB family
EXW42_17985	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW42_17990	COG1115	amino acid carrier protein
EXW42_17995	COG1012	belongs to the aldehyde dehydrogenase family
EXW42_18000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW42_18010	COG3938	Belongs to the proline racemase family
EXW42_18015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW42_18055	COG0586	Pfam SNARE associated Golgi protein
EXW42_18070	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW42_18075	COG4166	transmembrane transport
EXW42_18085	COG4948	Mandelate Racemase Muconate Lactonizing
EXW42_18105	COG0667	Aldo Keto reductase
EXW42_18145	COG2936	dipeptidyl-peptidase activity
EXW42_18155	COG0745	RESPONSE REGULATOR receiver
EXW42_18175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW42_18180	COG1164	Oligoendopeptidase f
EXW42_18195	COG1307	EDD domain protein, DegV family
EXW42_18225	COG1335	isochorismatase
EXW42_18240	COG2814	Major facilitator Superfamily
EXW42_18250	COG1664	Polymer-forming cytoskeletal
EXW42_18255	COG0789	Transcriptional regulator
EXW42_18260	COG4533	DNA binding
EXW42_18265	COG0477	Major facilitator Superfamily
EXW42_18265	COG2814	Major facilitator Superfamily
EXW42_18285	COG2261	transglycosylase associated protein
EXW42_18300	COG2226	methyltransferase
EXW42_18335	COG0436	Aminotransferase
EXW42_18340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW42_18365	COG1131	(ABC) transporter
EXW42_18370	COG2188	Transcriptional regulator
EXW42_18415	COG0628	permease
EXW42_18460	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW42_18470	COG0697	spore germination
EXW42_18520	COG2814	Major facilitator Superfamily
EXW42_18525	COG1368	sulfuric ester hydrolase activity
EXW42_18540	COG0488	(ABC) transporter
EXW42_18545	COG1033	growth of symbiont in host cell
EXW42_18545	COG2409	Drug exporters of the RND superfamily
EXW42_18550	COG1309	transcriptional regulator
EXW42_18570	COG0287	Prephenate dehydrogenase
EXW42_18585	COG1605	Chorismate mutase
EXW42_18585	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW42_18635	COG1388	LysM domain
EXW42_18635	COG3584	3D domain protein
EXW42_18645	COG0346	lactoylglutathione lyase activity
EXW42_18655	COG0431	NADPH-dependent FMN reductase
EXW42_18685	COG0579	oxidoreductase
EXW42_18690	COG1879	ABC-type sugar transport system periplasmic component
EXW42_18700	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW42_18705	COG1129	ABC transporter
EXW42_18710	COG2390	Transcriptional regulator
EXW42_18730	COG2226	methyltransferase
EXW42_18750	COG2329	Antibiotic biosynthesis monooxygenase
EXW42_18775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW42_18780	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW42_18785	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW42_18790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW42_18795	COG3239	Fatty acid desaturase
EXW42_18815	COG3842	ATPase activity
EXW42_18840	COG1175	transmembrane transport
EXW42_18845	COG1349	DNA-binding transcription factor activity
EXW42_18855	COG3655	Transcriptional regulator
EXW42_18875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW42_18880	COG0346	lactoylglutathione lyase activity
EXW42_18915	COG0714	Associated with various cellular activities
EXW42_18935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW42_18940	COG0753	catalase activity
EXW42_18950	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW42_18975	COG0714	Associated with various cellular activities
EXW42_18985	COG0778	Nitroreductase
EXW42_18990	COG1846	Transcriptional regulator
EXW42_19015	COG3831	ATPase activity
EXW42_19015	COG4884	unkown
EXW42_19035	COG2207	Transcriptional regulator
EXW42_19040	COG0456	acetyltransferase
EXW42_19055	COG0697	spore germination
EXW42_19060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW42_19090	COG0814	amino acid
EXW42_19095	COG0697	spore germination
EXW42_19105	COG0642	Histidine kinase
EXW42_19110	COG0745	RESPONSE REGULATOR receiver
EXW42_19115	COG0596	Alpha beta hydrolase
EXW42_19125	COG0456	acetyltransferase
EXW42_19125	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW42_19150	COG0730	response to heat
EXW42_19160	COG0833	amino acid
EXW42_19170	COG4335	DNA alkylation repair
EXW42_19200	COG0681	Belongs to the peptidase S26 family
EXW42_19205	COG0768	penicillin binding
EXW42_19220	COG3104	oligopeptide transport
EXW42_19225	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW42_19240	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW42_19245	COG1984	allophanate hydrolase subunit 2
EXW42_19250	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW42_19255	COG1414	Transcriptional regulator
EXW42_19275	COG1960	acyl-CoA dehydrogenase activity
EXW42_19300	COG0640	Transcriptional regulator
EXW42_19310	COG3314	Sporulation integral membrane protein YlbJ
EXW42_19330	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW42_19335	COG0577	efflux transmembrane transporter activity
EXW42_19340	COG0577	efflux transmembrane transporter activity
EXW42_19345	COG1136	(ABC) transporter
EXW42_19380	COG0574	Belongs to the PEP-utilizing enzyme family
EXW42_19380	COG3848	Pyruvate phosphate dikinase
EXW42_19390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW42_19415	COG5002	protein histidine kinase activity
EXW42_19420	COG0745	RESPONSE REGULATOR receiver
EXW42_19430	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW42_19450	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW42_19455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW42_19460	COG1121	(ABC) transporter
EXW42_19485	COG0798	PFAM Bile acid sodium symporter
EXW42_19490	COG0346	lactoylglutathione lyase activity
EXW42_19495	COG0640	Transcriptional regulator
EXW42_19510	COG1309	transcriptional regulator
EXW42_19520	COG1522	sequence-specific DNA binding
EXW42_19540	COG0346	lactoylglutathione lyase activity
EXW42_19570	COG0745	RESPONSE REGULATOR receiver
EXW42_19575	COG5002	protein histidine kinase activity
EXW42_19575	COG3850	Histidine kinase
EXW42_19610	COG1073	alpha beta
EXW42_19620	COG0814	amino acid
EXW42_19625	COG1760	l-serine dehydratase
EXW42_19630	COG1760	l-serine dehydratase
EXW42_19640	COG5002	protein histidine kinase activity
EXW42_19645	COG0745	RESPONSE REGULATOR receiver
EXW42_19655	COG5002	protein histidine kinase activity
EXW42_19680	COG4977	sequence-specific DNA binding
EXW42_19720	COG2814	Major facilitator Superfamily
EXW42_19735	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW42_19755	COG1476	TRANSCRIPTIONal
EXW42_19765	COG2226	methyltransferase
EXW42_19780	COG1696	Membrane protein involved in D-alanine export
EXW42_19790	COG1690	Belongs to the RtcB family
EXW42_19805	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW42_19820	COG1136	(ABC) transporter
EXW42_19825	COG0577	efflux transmembrane transporter activity
EXW42_19840	COG5002	protein histidine kinase activity
EXW42_19840	COG3850	Histidine kinase
EXW42_19850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW42_19865	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW42_19885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW42_19930	COG2814	Major facilitator Superfamily
EXW42_20165	COG2849	repeat protein
EXW42_20170	COG5444	nuclease activity
EXW42_20185	COG5444	nuclease activity
EXW42_20275	COG0477	Major facilitator Superfamily
EXW42_20290	COG1846	Transcriptional regulator
EXW42_20295	COG2814	Major facilitator Superfamily
EXW42_20345	COG1329	Transcriptional regulator
EXW42_20400	COG5002	protein histidine kinase activity
EXW42_20415	COG1136	(ABC) transporter
EXW42_20430	COG1131	(ABC) transporter
EXW42_20510	COG0789	Transcriptional regulator
EXW42_20550	COG4187	Peptidase family M20/M25/M40
EXW42_20555	COG1414	Transcriptional regulator
EXW42_20565	COG0833	amino acid
EXW42_20575	COG2031	fatty acid transporter
EXW42_20585	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW42_20635	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW42_20640	COG1288	antiporter activity
EXW42_20645	COG2356	endonuclease I
EXW42_20650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW42_20655	COG3620	sequence-specific DNA binding
EXW42_20675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW42_20695	COG1785	Belongs to the alkaline phosphatase family
EXW42_20700	COG0778	Nitroreductase
EXW42_20705	COG1733	regulation of RNA biosynthetic process
EXW42_20720	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_20730	COG1131	(ABC) transporter
EXW42_20760	COG1011	Hydrolase
EXW42_20765	COG2365	Tyrosine phosphatase family
EXW42_20790	COG0346	lactoylglutathione lyase activity
EXW42_20795	COG1940	carbohydrate kinase activity
EXW42_20800	COG0738	Major facilitator superfamily
EXW42_20805	COG0110	maltose O-acetyltransferase activity
EXW42_20820	COG0628	permease
EXW42_20825	COG2261	transglycosylase associated protein
EXW42_20855	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW42_20865	COG1253	flavin adenine dinucleotide binding
EXW42_20870	COG0789	Transcriptional regulator
EXW42_20880	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW42_20905	COG0697	spore germination
EXW42_20915	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW42_20920	COG3813	Protein conserved in bacteria
EXW42_20925	COG2706	6-phosphogluconolactonase activity
EXW42_20930	COG1070	Carbohydrate kinase
EXW42_20940	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW42_20945	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW42_20960	COG0814	amino acid
EXW42_20980	COG1393	Belongs to the ArsC family
EXW42_20990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW42_21005	COG0494	nUDIX hydrolase
EXW42_21020	COG0384	phenazine biosynthesis protein PhzF
EXW42_21030	COG0318	PFAM AMP-dependent synthetase and ligase
EXW42_21035	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW42_21040	COG1733	regulation of RNA biosynthetic process
EXW42_21055	COG1191	sigma factor activity
EXW42_21070	COG1876	peptidase activity
EXW42_21115	COG0741	lytic transglycosylase activity
EXW42_21140	COG5002	protein histidine kinase activity
EXW42_21190	COG0814	amino acid
EXW42_21215	COG1151	hydroxylamine reductase activity
EXW42_21245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW42_21255	COG2072	flavoprotein involved in K transport
EXW42_21295	COG0604	alcohol dehydrogenase
EXW42_21300	COG1113	amino acid transport
EXW42_21310	COG2814	Major facilitator Superfamily
EXW42_21320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW42_21325	COG1012	belongs to the aldehyde dehydrogenase family
EXW42_21335	COG0534	Mate efflux family protein
EXW42_21340	COG1012	belongs to the aldehyde dehydrogenase family
EXW42_21345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW42_21360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW42_21365	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW42_21385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW42_21390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW42_21395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW42_21400	COG3739	integral membrane protein
EXW42_21440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW42_21445	COG0583	DNA-binding transcription factor activity
EXW42_21470	COG1193	negative regulation of DNA recombination
EXW42_21490	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW42_21495	COG1164	Oligoendopeptidase f
EXW42_21500	COG2957	Belongs to the agmatine deiminase family
EXW42_21520	COG3781	membrane
EXW42_21535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW42_21570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW42_21575	COG0640	Transcriptional regulator
EXW42_21580	COG0604	alcohol dehydrogenase
EXW42_21585	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW42_21595	COG0457	Tetratricopeptide repeat
EXW42_21600	COG2808	Putative FMN-binding domain
EXW42_21610	COG0277	FAD linked oxidase domain protein
EXW42_21630	COG1285	pathogenesis
EXW42_21640	COG2514	catechol 2,3-dioxygenase activity
EXW42_21645	COG2720	vancomycin resistance protein
EXW42_21670	COG1278	Cold shock
EXW42_21680	COG0716	FMN binding
EXW42_21690	COG0494	nUDIX hydrolase
EXW42_21710	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_21720	COG0165	Argininosuccinate lyase
EXW42_21735	COG4145	pantothenate transmembrane transporter activity
EXW42_21745	COG1012	belongs to the aldehyde dehydrogenase family
EXW42_21750	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_21760	COG1657	PFAM Prenyltransferase squalene oxidase
EXW42_21765	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW42_21770	COG2962	Rard protein
EXW42_21775	COG3326	Membrane
EXW42_21780	COG0531	amino acid
EXW42_21815	COG2226	methyltransferase
EXW42_21820	COG4166	transmembrane transport
EXW42_21825	COG4166	transmembrane transport
EXW42_21830	COG4166	transmembrane transport
EXW42_21835	COG1316	TRANSCRIPTIONal
EXW42_21845	COG1595	DNA-templated transcription, initiation
EXW42_21855	COG1131	(ABC) transporter
EXW42_21875	COG0673	inositol 2-dehydrogenase activity
EXW42_21880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW42_21885	COG0187	DNA topoisomerase II activity
EXW42_21890	COG1832	CoA-binding protein
EXW42_21895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW42_21900	COG0745	RESPONSE REGULATOR receiver
EXW42_21910	COG1328	CTP reductase activity
EXW42_21920	COG4841	protein insertion into membrane
EXW42_21925	COG0824	Thioesterase
EXW42_21950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW42_21970	COG1132	(ABC) transporter
EXW42_21975	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW42_22005	COG2211	Major facilitator Superfamily
EXW42_22015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW42_22030	COG0183	Belongs to the thiolase family
EXW42_22035	COG0318	PFAM AMP-dependent synthetase and ligase
EXW42_22040	COG1268	BioY protein
EXW42_22045	COG0318	PFAM AMP-dependent synthetase and ligase
EXW42_22050	COG1396	sequence-specific DNA binding
EXW42_22070	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EXW42_22090	COG0830	nickel cation binding
EXW42_22130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW42_22145	COG5002	protein histidine kinase activity
EXW42_22155	COG0400	carboxylic ester hydrolase activity
EXW42_22160	COG0346	lactoylglutathione lyase activity
EXW42_22165	COG0069	glutamate synthase activity
EXW42_22170	COG1902	pentaerythritol trinitrate reductase activity
EXW42_22180	COG1329	Transcriptional regulator
EXW42_22185	COG0010	Belongs to the arginase family
EXW42_22195	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW42_22200	COG2986	histidine ammonia-lyase
EXW42_22210	COG2226	methyltransferase
EXW42_22240	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW42_22245	COG0785	Cytochrome C biogenesis protein
EXW42_22260	COG1473	amidohydrolase
EXW42_22265	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW42_22270	COG1131	(ABC) transporter
EXW42_22280	COG0583	DNA-binding transcription factor activity
EXW42_22290	COG1346	cytolysis
EXW42_22295	COG1051	belongs to the nudix hydrolase family
EXW42_22305	COG0730	response to heat
EXW42_22315	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW42_22315	COG3409	Peptidoglycan-binding domain 1 protein
EXW42_22335	COG1132	(ABC) transporter
EXW42_22340	COG1132	(ABC) transporter
EXW42_22345	COG3763	UPF0154 protein
EXW42_22365	COG3639	organic phosphonate transmembrane transporter activity
EXW42_22375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW42_22380	COG0737	Belongs to the 5'-nucleotidase family
EXW42_22390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW42_22395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW42_22410	COG1695	Transcriptional regulator
EXW42_22415	COG1132	(ABC) transporter
EXW42_22445	COG0367	asparagine synthase
EXW42_22450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW42_22460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW42_22470	COG3420	alginic acid biosynthetic process
EXW42_22470	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW42_22480	COG1442	glycosyl transferase family 8
EXW42_22485	COG1216	Glycosyl transferase, family 2
EXW42_22485	COG1442	glycosyl transferase family 8
EXW42_22500	COG0297	glycogen (starch) synthase activity
EXW42_22510	COG0438	transferase activity, transferring glycosyl groups
EXW42_22520	COG1216	Glycosyl transferase, family 2
EXW42_22525	COG0438	transferase activity, transferring glycosyl groups
EXW42_22530	COG0438	transferase activity, transferring glycosyl groups
EXW42_22535	COG1086	Polysaccharide biosynthesis protein
EXW42_22540	COG0489	protein tyrosine kinase activity
EXW42_22545	COG3944	biosynthesis protein
EXW42_22550	COG0174	glutamine synthetase
EXW42_22555	COG0789	Transcriptional regulator
EXW42_22560	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW42_22565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW42_22570	COG2860	membrane
EXW42_22575	COG0464	growth
EXW42_22595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW42_22605	COG1388	LysM domain
EXW42_22605	COG3584	3D domain protein
EXW42_22610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW42_22610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW42_22610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW42_22615	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW42_22620	COG1349	DNA-binding transcription factor activity
EXW42_22625	COG1979	alcohol dehydrogenase
EXW42_22630	COG2322	membrane
EXW42_22640	COG1113	amino acid transport
EXW42_22655	COG1473	amidohydrolase
EXW42_22660	COG1408	metallophosphoesterase
EXW42_22665	COG2116	formate transmembrane transporter activity
EXW42_22680	COG2217	Heavy metal translocating P-type atpase
EXW42_22685	COG2608	mercury ion transmembrane transporter activity
EXW42_22690	COG1937	Protein conserved in bacteria
EXW42_22720	COG4566	intracellular signal transduction
EXW42_22725	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW42_22730	COG2819	hydrolase of the alpha beta superfamily
EXW42_22735	COG1120	ATPase activity
EXW42_22740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW42_22745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW42_22750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW42_22755	COG0708	Exodeoxyribonuclease III
EXW42_22760	COG2169	Transcriptional regulator
EXW42_22765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW42_22770	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW42_22775	COG2706	6-phosphogluconolactonase activity
EXW42_22780	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW42_22785	COG2364	Membrane
EXW42_22795	COG0346	lactoylglutathione lyase activity
EXW42_22800	COG5001	Diguanylate cyclase
EXW42_22800	COG3300	MHYT domain
EXW42_22840	COG1346	cytolysis
EXW42_22850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW42_22855	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW42_22855	COG0596	Alpha beta hydrolase
EXW42_22860	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW42_22875	COG2188	Transcriptional regulator
EXW42_22880	COG2723	6-phospho-beta-galactosidase activity
EXW42_22885	COG0823	Involved in the tonB-independent uptake of proteins
EXW42_22890	COG3773	Cell wall hydrolase
EXW42_22900	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW42_22910	COG1131	(ABC) transporter
EXW42_22945	COG1131	(ABC) transporter
EXW42_22960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW42_22965	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW42_22975	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW42_22980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW42_22985	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW42_22990	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW42_22990	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW42_23000	COG2359	stage V sporulation protein S
EXW42_23005	COG1692	metallophosphoesterase
EXW42_23010	COG1418	mRNA catabolic process
EXW42_23015	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW42_23020	COG1058	Belongs to the CinA family
EXW42_23020	COG1546	Belongs to the CinA family
EXW42_23025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW42_23030	COG1426	Protein conserved in bacteria
EXW42_23045	COG0300	oxidoreductase activity
EXW42_23050	COG0612	Peptidase, M16
EXW42_23055	COG0612	Peptidase, M16
EXW42_23060	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW42_23065	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW42_23070	COG3845	ABC transporter
EXW42_23075	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW42_23080	COG2188	Transcriptional regulator
EXW42_23085	COG1674	ftsk spoiiie
EXW42_23095	COG0740	serine-type endopeptidase activity
EXW42_23100	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW42_23110	COG0527	aspartate kinase activity
EXW42_23115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW42_23120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW42_23125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW42_23130	COG1873	PFAM PRC-barrel domain
EXW42_23135	COG0612	Peptidase, M16
EXW42_23140	COG0726	polysaccharide deacetylase
EXW42_23145	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW42_23155	COG0196	riboflavin kinase activity
EXW42_23165	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW42_23170	COG1550	Protein conserved in bacteria
EXW42_23175	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW42_23180	COG1358	cellular component organization or biogenesis
EXW42_23185	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW42_23190	COG0195	Participates in both transcription termination and antitermination
EXW42_23195	COG0779	Required for maturation of 30S ribosomal subunits
EXW42_23205	COG0442	prolyl-tRNA aminoacylation
EXW42_23210	COG0750	zinc metalloprotease
EXW42_23220	COG4589	Belongs to the CDS family
EXW42_23230	COG0233	cytoplasmic translational termination
EXW42_23235	COG0528	UMP kinase activity
EXW42_23240	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW42_23250	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW42_23255	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW42_23260	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW42_23265	COG4974	Belongs to the 'phage' integrase family
EXW42_23270	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW42_23275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW42_23280	COG0758	DNA mediated transformation
EXW42_23285	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW42_23290	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW42_23295	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW42_23310	COG0335	large ribosomal subunit rRNA binding
EXW42_23315	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW42_23320	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW42_23325	COG1837	Belongs to the UPF0109 family
EXW42_23335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW42_23345	COG0552	protein localization to endoplasmic reticulum
EXW42_23350	COG1196	nuclear chromosome segregation
EXW42_23355	COG0571	ribonuclease III activity
EXW42_23360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW42_23365	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_23370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW42_23375	COG0416	fatty acid biosynthetic process
EXW42_23380	COG1349	DNA-binding transcription factor activity
EXW42_23380	COG2050	protein possibly involved in aromatic compounds catabolism
EXW42_23385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW42_23390	COG1461	Dihydroxyacetone kinase
EXW42_23395	COG1302	Protein conserved in bacteria
EXW42_23410	COG1564	THIamine pyrophosphokinase
EXW42_23415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW42_23425	COG0515	serine threonine protein kinase
EXW42_23425	COG2815	serine threonine protein kinase
EXW42_23430	COG0631	protein serine/threonine phosphatase activity
EXW42_23435	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW42_23440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW42_23440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW42_23445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW42_23450	COG0242	peptide deformylase activity
EXW42_23455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW42_23460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW42_23465	COG1758	RNA polymerase activity
EXW42_23480	COG1561	YicC-like family, N-terminal region
EXW42_23485	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW42_23495	COG0006	proline dipeptidase activity
EXW42_23515	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW42_23525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EXW42_23535	COG0167	dihydroorotate dehydrogenase activity
EXW42_23540	COG0543	2 iron, 2 sulfur cluster binding
EXW42_23545	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW42_23555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW42_23560	COG0540	Belongs to the ATCase OTCase family
EXW42_23570	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW42_23575	COG0564	pseudouridine synthase activity
EXW42_23580	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW42_23590	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW42_23595	COG3599	regulation of cell shape
EXW42_23600	COG2302	S4 RNA-binding domain
EXW42_23605	COG0762	integral membrane protein
EXW42_23610	COG1799	cell septum assembly
EXW42_23615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW42_23625	COG1873	PFAM PRC-barrel domain
EXW42_23630	COG1191	sigma factor activity
EXW42_23635	COG1191	sigma factor activity
EXW42_23645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW42_23650	COG0849	cell division
EXW42_23655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW42_23670	COG0772	Belongs to the SEDS family
EXW42_23675	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW42_23680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW42_23685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW42_23690	COG0768	penicillin binding
EXW42_23695	COG0768	penicillin binding
EXW42_23705	COG0275	rRNA processing
EXW42_23710	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW42_23715	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW42_23720	COG0454	-acetyltransferase
EXW42_23730	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW42_23735	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW42_23740	COG1323	Belongs to the UPF0348 family
EXW42_23745	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW42_23750	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW42_23755	COG3314	Sporulation integral membrane protein YlbJ
EXW42_23765	COG0742	ribosomal rna small subunit methyltransferase
EXW42_23775	COG4471	UPF0298 protein
EXW42_23780	COG3679	Belongs to the UPF0342 family
EXW42_23785	COG0406	alpha-ribazole phosphatase activity
EXW42_23800	COG2340	Cysteine-rich secretory protein family
EXW42_23810	COG3336	cytochrome c oxidase
EXW42_23835	COG0109	protoheme IX farnesyltransferase activity
EXW42_23840	COG1612	heme a metabolic process
EXW42_23845	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW42_23855	COG0772	Belongs to the SEDS family
EXW42_23860	COG4838	Belongs to the UPF0358 family
EXW42_23865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW42_23870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW42_23880	COG4896	Protein conserved in bacteria
EXW42_23895	COG1217	gtp-binding protein TYPA
EXW42_23905	COG0483	inositol monophosphate 1-phosphatase activity
EXW42_23915	COG4493	Belongs to the UPF0637 family
EXW42_23920	COG4476	Belongs to the UPF0223 family
EXW42_23925	COG1982	Orn Lys Arg decarboxylase major
EXW42_23970	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW42_23975	COG0022	dehydrogenase e1 component
EXW42_23980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW42_23995	COG0561	phosphatase activity
EXW42_24005	COG5503	Protein of unknown function (DUF1447)
EXW42_24010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW42_24015	COG0569	domain protein
EXW42_24025	COG1473	amidohydrolase
EXW42_24030	COG2171	N-acyltransferase activity
EXW42_24035	COG0583	DNA-binding transcription factor activity
EXW42_24040	COG0517	IMP dehydrogenase activity
EXW42_24050	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW42_24060	COG4703	Protein of unknown function (DUF1797)
EXW42_24075	COG2200	EAL domain
EXW42_24080	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_24085	COG1408	metallophosphoesterase
EXW42_24130	COG2814	Major facilitator Superfamily
EXW42_24140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW42_24150	COG3209	COG3209 Rhs family protein
EXW42_24160	COG2205	protein histidine kinase activity
EXW42_24170	COG0436	Aminotransferase
EXW42_24175	COG1609	Transcriptional regulator
EXW42_24180	COG3833	ABC-type maltose transport systems, permease component
EXW42_24185	COG1175	transmembrane transport
EXW42_24190	COG2182	Extracellular solute-binding protein
EXW42_24200	COG0366	Alpha amylase catalytic
EXW42_24205	COG3842	ATPase activity
EXW42_24250	COG0183	Belongs to the thiolase family
EXW42_24285	COG1695	Transcriptional regulator
EXW42_24290	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_24300	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW42_24305	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW42_24310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW42_24315	COG0436	Aminotransferase
EXW42_24320	COG1850	ribulose-bisphosphate carboxylase activity
EXW42_24325	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW42_24330	COG0235	Class ii aldolase
EXW42_24335	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW42_24350	COG2084	Dehydrogenase
EXW42_24360	COG2199	diguanylate cyclase activity
EXW42_24365	COG0778	Nitroreductase
EXW42_24390	COG1263	PTS System
EXW42_24390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW42_24390	COG2190	(PTS) system
EXW42_24395	COG3711	transcriptional antiterminator
EXW42_24405	COG2188	Transcriptional regulator
EXW42_24410	COG0363	glucosamine-6-phosphate deaminase activity
EXW42_24415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW42_24425	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW42_24435	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW42_24445	COG1547	Domain of unknown function (DUF309)
EXW42_24455	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW42_24460	COG4086	secreted protein
EXW42_24465	COG0561	phosphatase activity
EXW42_24470	COG0697	spore germination
EXW42_24485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW42_24510	COG0733	neurotransmitter:sodium symporter activity
EXW42_24530	COG1686	Belongs to the peptidase S11 family
EXW42_24535	COG1725	Transcriptional regulator
EXW42_24540	COG1131	(ABC) transporter
EXW42_24560	COG1846	Transcriptional regulator
EXW42_24575	COG0598	Magnesium transport protein CorA
EXW42_24590	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW42_24600	COG4974	Belongs to the 'phage' integrase family
EXW42_24610	COG0735	belongs to the Fur family
EXW42_24615	COG1300	Membrane
EXW42_24635	COG0667	Aldo Keto reductase
EXW42_24640	COG0656	L-ascorbic acid biosynthetic process
EXW42_24645	COG0456	acetyltransferase
EXW42_24645	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW42_24655	COG4085	toxin activity
EXW42_24655	COG0737	Belongs to the 5'-nucleotidase family
EXW42_24655	COG1525	nuclease
EXW42_24660	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW42_24670	COG0596	Alpha beta hydrolase
EXW42_24675	COG2056	Na+-H+ antiporter family
EXW42_24680	COG1609	Transcriptional regulator
EXW42_24685	COG0456	acetyltransferase
EXW42_24690	COG1073	alpha beta
EXW42_24705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW42_24705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW42_24710	COG0307	riboflavin synthase, alpha
EXW42_24715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW42_24715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW42_24730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW42_24735	COG4106	trans-aconitate 2-methyltransferase activity
EXW42_24740	COG1073	alpha beta
EXW42_24740	COG2226	methyltransferase
EXW42_24745	COG0156	8-amino-7-oxononanoate synthase activity
EXW42_24755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW42_24765	COG1757	Na H antiporter
EXW42_24770	COG0737	Belongs to the 5'-nucleotidase family
EXW42_24780	COG1522	sequence-specific DNA binding
EXW42_24815	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW42_24825	COG0300	oxidoreductase activity
EXW42_24830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW42_24835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW42_24840	COG1760	l-serine dehydratase
EXW42_24845	COG1760	l-serine dehydratase
EXW42_24855	COG1234	tRNA 3'-trailer cleavage
EXW42_24880	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW42_24885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW42_24895	COG1376	ErfK ybiS ycfS ynhG family protein
EXW42_24900	COG4129	membrane
EXW42_24905	COG1126	abc transporter atp-binding protein
EXW42_24910	COG0765	amino acid transport
EXW42_24915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW42_24930	COG2816	NAD+ diphosphatase activity
EXW42_24935	COG2323	membrane
EXW42_24940	COG0772	Belongs to the SEDS family
EXW42_24950	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW42_24955	COG0022	dehydrogenase e1 component
EXW42_24960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW42_24965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW42_24970	COG3426	butyrate kinase activity
EXW42_24980	COG0280	phosphate acetyltransferase
EXW42_24990	COG3829	transcription factor binding
EXW42_24990	COG3290	protein histidine kinase activity
EXW42_25000	COG0584	glycerophosphoryl diester phosphodiesterase
EXW42_25005	COG3093	addiction module antidote protein HigA
EXW42_25045	COG0745	RESPONSE REGULATOR receiver
EXW42_25055	COG0750	zinc metalloprotease
EXW42_25060	COG0497	DNA recombination
EXW42_25065	COG1438	arginine binding
EXW42_25070	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW42_25075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW42_25080	COG0142	geranyltranstransferase activity
EXW42_25085	COG1722	exodeoxyribonuclease VII activity
EXW42_25090	COG1570	exodeoxyribonuclease VII activity
EXW42_25095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW42_25100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW42_25105	COG1302	Protein conserved in bacteria
EXW42_25110	COG0439	Biotin carboxylase
EXW42_25115	COG0511	ligase activity, forming carbon-carbon bonds
EXW42_25160	COG3854	ATPases associated with a variety of cellular activities
EXW42_25180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW42_25185	COG0006	proline dipeptidase activity
EXW42_25190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW42_25200	COG3872	metal-dependent enzyme
EXW42_25210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW42_25245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW42_25255	COG1609	Transcriptional regulator
EXW42_25265	COG2076	Multidrug Resistance protein
EXW42_25270	COG2076	Multidrug Resistance protein
EXW42_25310	COG1725	Transcriptional regulator
EXW42_25325	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW42_25330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW42_25335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW42_25340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW42_25370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW42_25395	COG4970	Tfp pilus assembly protein FimT
EXW42_25405	COG1459	type II secretion system
EXW42_25410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW42_25465	COG0646	methionine synthase
EXW42_25465	COG1410	methionine synthase
EXW42_25470	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW42_25470	COG0646	methionine synthase
EXW42_25475	COG0626	cystathionine gamma-synthase activity
EXW42_25480	COG0626	cystathionine gamma-synthase activity
EXW42_25500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW42_25510	COG1940	carbohydrate kinase activity
EXW42_25515	COG4483	Protein conserved in bacteria
EXW42_25520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW42_25525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW42_25530	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW42_25535	COG0704	Plays a role in the regulation of phosphate uptake
EXW42_25545	COG0581	inorganic phosphate transmembrane transporter activity
EXW42_25550	COG0573	inorganic phosphate transmembrane transporter activity
EXW42_25555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW42_25560	COG0768	penicillin binding
EXW42_25565	COG0477	Major facilitator Superfamily
EXW42_25570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW42_25590	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW42_25595	COG0735	belongs to the Fur family
EXW42_25600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW42_25605	COG1121	(ABC) transporter
EXW42_25610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW42_25620	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW42_25635	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW42_25640	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW42_25645	COG2384	SAM-dependent methyltransferase
EXW42_25650	COG2010	Cytochrome c
EXW42_25655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW42_25660	COG0358	DNA primase activity
EXW42_25670	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW42_25675	COG0517	IMP dehydrogenase activity
EXW42_25680	COG1381	Involved in DNA repair and RecF pathway recombination
EXW42_25690	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW42_25695	COG0295	cytidine deaminase activity
EXW42_25700	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW42_25705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW42_25710	COG1480	7TM receptor with intracellular HD hydrolase
EXW42_25715	COG1702	phosphate starvation-inducible protein PhoH
EXW42_25730	COG1610	YqeY-like protein
EXW42_25735	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW42_25740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW42_25745	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW42_25755	COG0484	heat shock protein binding
EXW42_25760	COG0443	Heat shock 70 kDa protein
EXW42_25770	COG1420	regulation of RNA biosynthetic process
EXW42_25775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW42_25780	COG1733	regulation of RNA biosynthetic process
EXW42_25785	COG0481	GTPase activity
EXW42_25795	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW42_25800	COG0268	Binds directly to 16S ribosomal RNA
EXW42_25805	COG1466	dna polymerase III delta subunit
EXW42_25815	COG0658	competence protein
EXW42_25815	COG2333	competence protein COMEC
EXW42_25820	COG2131	deaminase
EXW42_25825	COG1555	photosystem II stabilization
EXW42_25825	COG1596	polysaccharide export
EXW42_25830	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW42_25835	COG2226	methyltransferase
EXW42_25840	COG0799	negative regulation of ribosome biogenesis
EXW42_25845	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW42_25850	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW42_25855	COG1534	Rna-binding protein
EXW42_25860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW42_25865	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW42_25870	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW42_25880	COG0688	phosphatidylethanolamine metabolic process
EXW42_25890	COG1595	DNA-templated transcription, initiation
EXW42_25895	COG2357	RelA SpoT domain protein
EXW42_25905	COG1785	Belongs to the alkaline phosphatase family
EXW42_25915	COG2267	carboxylic ester hydrolase activity
EXW42_25950	COG1404	Belongs to the peptidase S8 family
EXW42_25955	COG3186	Phenylalanine-4-hydroxylase
EXW42_25960	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW42_25965	COG2514	catechol 2,3-dioxygenase activity
EXW42_25970	COG2259	Doxx family
EXW42_26010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW42_26020	COG1454	alcohol dehydrogenase
EXW42_26020	COG1012	belongs to the aldehyde dehydrogenase family
EXW42_26025	COG0626	cystathionine gamma-synthase activity
EXW42_26030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW42_26035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW42_26040	COG2226	methyltransferase
EXW42_26055	COG0768	penicillin binding
EXW42_26060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW42_26065	COG0572	uridine kinase
EXW42_26070	COG0826	peptidase U32
EXW42_26075	COG0826	peptidase U32
EXW42_26080	COG4122	O-methyltransferase activity
EXW42_26085	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW42_26095	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW42_26100	COG4472	Bacterial protein of unknown function (DUF965)
EXW42_26105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW42_26115	COG0628	permease
EXW42_26135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW42_26145	COG0482	sulfurtransferase activity
EXW42_26150	COG1104	cysteine desulfurase activity
EXW42_26155	COG1959	2 iron, 2 sulfur cluster binding
EXW42_26160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW42_26170	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW42_26175	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW42_26185	COG1490	D-aminoacyl-tRNA deacylase activity
EXW42_26190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW42_26195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW42_26200	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW42_26200	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW42_26205	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW42_26210	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW42_26210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW42_26220	COG2244	polysaccharide biosynthetic process
EXW42_26225	COG2323	membrane
EXW42_26235	COG1862	Preprotein translocase
EXW42_26240	COG0343	queuine tRNA-ribosyltransferase activity
EXW42_26245	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW42_26255	COG2255	four-way junction helicase activity
EXW42_26260	COG0632	four-way junction helicase activity
EXW42_26265	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW42_26290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW42_26295	COG0157	Belongs to the NadC ModD family
EXW42_26300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW42_26305	COG1104	cysteine desulfurase activity
EXW42_26310	COG1827	regulation of RNA biosynthetic process
EXW42_26315	COG2258	MOSC domain
EXW42_26320	COG0077	Prephenate dehydratase
EXW42_26325	COG0577	efflux transmembrane transporter activity
EXW42_26330	COG0577	efflux transmembrane transporter activity
EXW42_26335	COG1136	(ABC) transporter
EXW42_26340	COG5002	protein histidine kinase activity
EXW42_26345	COG0745	RESPONSE REGULATOR receiver
EXW42_26350	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW42_26355	COG3290	protein histidine kinase activity
EXW42_26365	COG2868	ribosomal protein
EXW42_26375	COG1530	ribonuclease E activity
EXW42_26380	COG1994	Peptidase M50
EXW42_26385	COG0739	heme binding
EXW42_26390	COG2894	cell division
EXW42_26395	COG0850	regulation of cytokinetic process
EXW42_26410	COG1077	Cell shape determining protein MreB Mrl
EXW42_26415	COG2003	Belongs to the UPF0758 family
EXW42_26420	COG0424	maF-like protein
EXW42_26435	COG0285	dihydrofolate synthase activity
EXW42_26450	COG1388	LysM domain
EXW42_26455	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW42_26460	COG0113	porphobilinogen synthase activity
EXW42_26465	COG1587	Uroporphyrinogen-III synthase
EXW42_26470	COG0181	hydroxymethylbilane synthase activity
EXW42_26475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW42_26480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW42_26485	COG1846	Transcriptional regulator
EXW42_26490	COG1764	response to oxidative stress
EXW42_26495	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW42_26505	COG0470	DNA polymerase III
EXW42_26505	COG1067	ATP-dependent peptidase activity
EXW42_26515	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW42_26545	COG0622	Phosphoesterase
EXW42_26555	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW42_26560	COG5401	PFAM Sporulation and spore germination
EXW42_26570	COG0477	Major facilitator Superfamily
EXW42_26575	COG2197	response regulator
EXW42_26580	COG2233	PERMEase
EXW42_26585	COG0402	S-adenosylhomocysteine deaminase activity
EXW42_26590	COG1983	PspC domain protein
EXW42_26595	COG1396	sequence-specific DNA binding
EXW42_26600	COG0697	spore germination
EXW42_26610	COG1959	2 iron, 2 sulfur cluster binding
EXW42_26615	COG1668	transmembrane transport
EXW42_26620	COG4152	abc transporter atp-binding protein
EXW42_26625	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW42_26630	COG1360	Flagellar Motor Protein
EXW42_26635	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW42_26645	COG1876	peptidase activity
EXW42_26650	COG0824	Thioesterase
EXW42_26655	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW42_26660	COG1053	succinate dehydrogenase
EXW42_26665	COG2009	succinate dehydrogenase
EXW42_26670	COG1719	4-vinyl reductase, 4VR
EXW42_26675	COG0322	excinuclease ABC activity
EXW42_26680	COG3118	belongs to the thioredoxin family
EXW42_26685	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW42_26690	COG2086	electron transfer activity
EXW42_26695	COG1024	Enoyl-CoA hydratase
EXW42_26700	COG1309	transcriptional regulator
EXW42_26705	COG0318	PFAM AMP-dependent synthetase and ligase
EXW42_26725	COG2318	DinB family
EXW42_26750	COG1131	(ABC) transporter
EXW42_26755	COG2205	protein histidine kinase activity
EXW42_26760	COG0745	RESPONSE REGULATOR receiver
EXW42_26765	COG4895	conserved protein (DUF2196)
EXW42_26770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW42_26780	COG4509	Sortase family
EXW42_26785	COG1120	ATPase activity
EXW42_26800	COG5386	Cell surface protein
EXW42_26810	COG5386	Cell surface protein
EXW42_26815	COG1114	Component of the transport system for branched-chain amino acids
EXW42_26825	COG1193	negative regulation of DNA recombination
EXW42_26830	COG1796	DNA polymerase
EXW42_26830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW42_26835	COG1286	toxin biosynthetic process
EXW42_26840	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW42_26845	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW42_26870	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW42_26875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW42_26885	COG1418	mRNA catabolic process
EXW42_26915	COG2814	Major facilitator Superfamily
EXW42_26920	COG1566	PFAM secretion protein HlyD family protein
EXW42_26925	COG1309	transcriptional regulator
EXW42_26930	COG1363	Peptidase, m42
EXW42_26940	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW42_26955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW42_26965	COG1484	DNA-dependent DNA replication
EXW42_26970	COG3611	Membrane attachment protein
EXW42_26975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW42_26980	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW42_26985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW42_26990	COG0237	dephospho-CoA kinase activity
EXW42_26995	COG1971	Probably functions as a manganese efflux pump
EXW42_27005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW42_27005	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW42_27010	COG5002	protein histidine kinase activity
EXW42_27015	COG0745	RESPONSE REGULATOR receiver
EXW42_27030	COG0039	L-malate dehydrogenase activity
EXW42_27035	COG0538	isocitrate dehydrogenase activity
EXW42_27040	COG0372	Belongs to the citrate synthase family
EXW42_27055	COG0628	permease
EXW42_27060	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW42_27070	COG0205	6-phosphofructokinase activity
EXW42_27080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW42_27085	COG1725	Transcriptional regulator
EXW42_27090	COG0281	malic enzyme
EXW42_27095	COG0587	DNA-directed DNA polymerase activity
EXW42_27110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW42_27130	COG4109	DRTGG domain
EXW42_27140	COG0006	proline dipeptidase activity
EXW42_27170	COG0662	Cupin 2, conserved barrel domain protein
EXW42_27180	COG1476	TRANSCRIPTIONal
EXW42_27205	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_27260	COG0673	inositol 2-dehydrogenase activity
EXW42_27265	COG0673	inositol 2-dehydrogenase activity
EXW42_27270	COG2169	Transcriptional regulator
EXW42_27515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW42_27525	COG0662	Cupin 2, conserved barrel domain protein
EXW42_27525	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EXW42_27590	COG3344	reverse transcriptase
EXW42_27615	COG2311	Membrane
EXW42_27650	COG1696	Membrane protein involved in D-alanine export
EXW42_27670	COG0745	RESPONSE REGULATOR receiver
EXW42_27695	COG1279	arginine transmembrane transporter activity
EXW42_27700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW42_27705	COG1175	transmembrane transport
EXW42_27710	COG0395	ABC-type sugar transport system, permease component
EXW42_27735	COG3842	ATPase activity
EXW42_27740	COG5002	protein histidine kinase activity
EXW42_27750	COG1136	(ABC) transporter
EXW42_27765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW42_27775	COG2707	UPF0756 membrane protein
EXW42_27785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW42_27920	COG2814	Major facilitator Superfamily
EXW42_28000	COG4977	sequence-specific DNA binding
EXW42_28015	COG0083	homoserine kinase activity
EXW42_28035	COG1309	transcriptional regulator
EXW42_28040	COG2814	Major facilitator Superfamily
EXW42_28050	COG2508	Transcriptional regulator
EXW42_28050	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW42_28055	COG0686	Belongs to the AlaDH PNT family
EXW42_28125	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW42_28180	COG1396	sequence-specific DNA binding
EXW42_28200	COG0840	transmembrane signaling receptor activity
EXW42_28205	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW42_28225	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW42_28230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW42_28235	COG0772	Belongs to the SEDS family
EXW42_28240	COG2239	Acts as a magnesium transporter
EXW42_28250	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW42_28265	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW42_28270	COG0519	Catalyzes the synthesis of GMP from XMP
EXW42_28280	COG1278	Cold shock
EXW42_28300	COG0024	Methionine aminopeptidase
EXW42_28335	COG4974	Belongs to the 'phage' integrase family
EXW42_28430	COG2357	RelA SpoT domain protein
EXW42_28435	COG2814	Major facilitator Superfamily
EXW42_28490	COG0776	regulation of translation
EXW42_28530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW42_28550	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW42_28575	COG3344	reverse transcriptase
EXW42_28625	COG0640	Transcriptional regulator
EXW42_28640	COG0457	Tetratricopeptide repeat
EXW42_28690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW42_28695	COG2040	homocysteine
EXW42_28700	COG0833	amino acid
EXW42_28800	COG1725	Transcriptional regulator
EXW42_28805	COG1131	(ABC) transporter
EXW42_28850	COG1329	Transcriptional regulator
EXW42_28875	COG0697	spore germination
EXW42_28945	COG0457	Tetratricopeptide repeat
EXW42_28975	COG1132	(ABC) transporter
EXW42_29025	COG1396	sequence-specific DNA binding
EXW42_29075	COG0653	protein targeting
EXW42_29190	COG0367	asparagine synthase
EXW42_29280	COG0542	response to heat
EXW42_29290	COG3397	chitin binding
EXW42_29365	COG1132	(ABC) transporter
EXW42_29405	COG1404	Belongs to the peptidase S8 family
EXW42_29415	COG2814	Major facilitator Superfamily
EXW42_29420	COG2234	aminopeptidase activity
EXW42_29430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW42_29445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW42_29450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW42_29455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW42_29465	COG0456	acetyltransferase
EXW42_29515	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW42_29520	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW42_29540	COG0746	molybdenum cofactor guanylyltransferase activity
EXW42_29555	COG0438	transferase activity, transferring glycosyl groups
EXW42_29560	COG0671	phosphoesterase, PA-phosphatase related
EXW42_29565	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW42_29570	COG2267	carboxylic ester hydrolase activity
EXW42_29590	COG1794	racemase activity, acting on amino acids and derivatives
EXW42_29600	COG1131	(ABC) transporter
EXW42_29610	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW42_29615	COG1242	4 iron, 4 sulfur cluster binding
EXW42_29630	COG1136	(ABC) transporter
EXW42_29645	COG0582	viral genome integration into host DNA
EXW42_29650	COG0490	domain, Protein
EXW42_29655	COG0475	glutathione-regulated potassium exporter activity
EXW42_29660	COG2814	Major facilitator Superfamily
EXW42_29665	COG0495	leucyl-tRNA aminoacylation
EXW42_29705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW42_29715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW42_29740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW42_29745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW42_29750	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW42_29755	COG0303	'Molybdopterin
EXW42_29760	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW42_29765	COG0314	molybdopterin synthase activity
EXW42_29790	COG1329	Transcriptional regulator
EXW42_29810	COG3832	glyoxalase III activity
EXW42_29820	COG2814	Major facilitator Superfamily
EXW42_29825	COG2081	HI0933 family
EXW42_29830	COG2244	polysaccharide biosynthetic process
EXW42_29835	COG1187	pseudouridine synthase activity
EXW42_29840	COG1349	DNA-binding transcription factor activity
EXW42_29845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW42_29855	COG1523	belongs to the glycosyl hydrolase 13 family
EXW42_29860	COG0510	thiamine kinase activity
EXW42_29870	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW42_29875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW42_29885	COG1363	Peptidase, m42
EXW42_29890	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW42_29895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW42_29900	COG4848	Belongs to the UPF0354 family
EXW42_29905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW42_29920	COG1674	ftsk spoiiie
EXW42_29930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW42_29940	COG1695	Transcriptional regulator
EXW42_29970	COG2309	aminopeptidase activity
EXW42_29980	COG3118	belongs to the thioredoxin family
EXW42_29985	COG4851	CamS sex pheromone cAM373 precursor
EXW42_29990	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW42_29990	COG1605	Chorismate mutase
EXW42_30000	COG1609	Transcriptional regulator
EXW42_30020	COG1970	mechanosensitive ion channel activity
EXW42_30030	COG0666	response to abiotic stimulus
EXW42_30035	COG5002	protein histidine kinase activity
EXW42_30040	COG0745	RESPONSE REGULATOR receiver
EXW42_30055	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW42_30060	COG0517	IMP dehydrogenase activity
EXW42_30065	COG0454	-acetyltransferase
EXW42_30070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW42_30075	COG0456	acetyltransferase
EXW42_30080	COG0110	maltose O-acetyltransferase activity
EXW42_30090	COG1595	DNA-templated transcription, initiation
EXW42_30115	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW42_30120	COG0626	cystathionine gamma-synthase activity
EXW42_30125	COG1956	GAF domain-containing protein
EXW42_30130	COG1309	transcriptional regulator
EXW42_30145	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW42_30150	COG1104	cysteine desulfurase activity
EXW42_30165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW42_30175	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW42_30190	COG3874	Sporulation protein YtfJ
EXW42_30195	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW42_30200	COG0827	DNA restriction-modification system
EXW42_30205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW42_30225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW42_30240	COG0137	argininosuccinate synthase activity
EXW42_30270	COG0589	response to stress
EXW42_30275	COG1028	Short-chain dehydrogenase reductase Sdr
EXW42_30280	COG0686	Belongs to the AlaDH PNT family
EXW42_30285	COG0745	RESPONSE REGULATOR receiver
EXW42_30290	COG2205	protein histidine kinase activity
EXW42_30325	COG0697	spore germination