locus-tag	class	description
EXW57_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW57_00010	COG0592	DNA-directed DNA polymerase activity
EXW57_00015	COG2501	S4 domain
EXW57_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW57_00025	COG0187	DNA topoisomerase II activity
EXW57_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW57_00065	COG0516	GMP reductase activity
EXW57_00065	COG0517	IMP dehydrogenase activity
EXW57_00070	COG1686	Belongs to the peptidase S11 family
EXW57_00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW57_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW57_00100	COG1428	Deoxynucleoside kinase
EXW57_00105	COG1428	Deoxynucleoside kinase
EXW57_00110	COG1335	isochorismatase
EXW57_00115	COG0590	tRNA wobble adenosine to inosine editing
EXW57_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW57_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW57_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW57_00180	COG1982	Orn Lys Arg decarboxylase major
EXW57_00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW57_00190	COG0470	DNA polymerase III
EXW57_00195	COG1774	PSP1 C-terminal conserved region
EXW57_00200	COG4467	Involved in initiation control of chromosome replication
EXW57_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW57_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW57_00220	COG2002	toxin-antitoxin pair type II binding
EXW57_00230	COG0084	hydrolase, TatD family'
EXW57_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW57_00250	COG4466	Protein conserved in bacteria
EXW57_00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW57_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW57_00270	COG0251	oxidation-reduction process
EXW57_00275	COG2088	sporulation resulting in formation of a cellular spore
EXW57_00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW57_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW57_00305	COG2002	toxin-antitoxin pair type II binding
EXW57_00310	COG2244	polysaccharide biosynthetic process
EXW57_00315	COG3956	TIGRFAM MazG family protein
EXW57_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW57_00340	COG1098	S1 RNA binding domain
EXW57_00355	COG2208	phosphoserine phosphatase activity
EXW57_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW57_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW57_00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW57_00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW57_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW57_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW57_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW57_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW57_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW57_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW57_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW57_00420	COG1396	sequence-specific DNA binding
EXW57_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW57_00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW57_00515	COG3880	PFAM UvrB UvrC protein
EXW57_00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW57_00525	COG0542	response to heat
EXW57_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW57_00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW57_00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW57_00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW57_00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW57_00560	COG1045	serine acetyltransferase
EXW57_00565	COG0215	cysteine-tRNA ligase activity
EXW57_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW57_00580	COG3688	RNA-binding protein containing a PIN domain
EXW57_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW57_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW57_00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW57_00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW57_00610	COG0081	regulation of translation
EXW57_00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW57_00620	COG0222	ribosome binding
EXW57_00625	COG2813	Specifically methylates the guanine in position
EXW57_00630	COG0085	RNA polymerase activity
EXW57_00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW57_00640	COG1358	cellular component organization or biogenesis
EXW57_00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW57_00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW57_00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW57_00665	COG0051	transcription antitermination factor activity, RNA binding
EXW57_00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW57_00675	COG0088	Forms part of the polypeptide exit tunnel
EXW57_00680	COG0089	rRNA binding
EXW57_00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW57_00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW57_00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW57_00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW57_00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW57_00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW57_00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW57_00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW57_00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW57_00760	COG1841	ribosomal large subunit assembly
EXW57_00765	COG0200	Binds to the 23S rRNA
EXW57_00770	COG0201	protein transport
EXW57_00775	COG0563	adenylate kinase activity
EXW57_00780	COG0024	Methionine aminopeptidase
EXW57_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW57_00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW57_00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW57_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW57_00835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW57_00840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW57_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_00855	COG0489	protein tyrosine kinase activity
EXW57_00865	COG2194	sulfuric ester hydrolase activity
EXW57_00870	COG0726	polysaccharide deacetylase
EXW57_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW57_00955	COG4856	YbbR-like protein
EXW57_00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW57_00990	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_00995	COG2011	ABC-type metal ion transport system permease component
EXW57_01005	COG1464	Belongs to the NlpA lipoprotein family
EXW57_01010	COG0604	alcohol dehydrogenase
EXW57_01020	COG0277	FAD linked oxidase domain protein
EXW57_01025	COG2271	Major facilitator Superfamily
EXW57_01035	COG2814	Major facilitator Superfamily
EXW57_01050	COG0601	transmembrane transport
EXW57_01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW57_01060	COG0444	Belongs to the ABC transporter superfamily
EXW57_01065	COG4608	Belongs to the ABC transporter superfamily
EXW57_01070	COG4166	transmembrane transport
EXW57_01080	COG2207	Transcriptional regulator
EXW57_01095	COG4166	transmembrane transport
EXW57_01100	COG4166	transmembrane transport
EXW57_01105	COG0656	L-ascorbic acid biosynthetic process
EXW57_01125	COG4149	molybdate abc transporter
EXW57_01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW57_01135	COG1910	domain protein
EXW57_01150	COG0697	spore germination
EXW57_01165	COG0204	Acyl-transferase
EXW57_01175	COG1609	Transcriptional regulator
EXW57_01185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_01200	COG5298	Protein conserved in bacteria
EXW57_01225	COG0488	(ABC) transporter
EXW57_01230	COG4585	Histidine kinase
EXW57_01235	COG2197	response regulator
EXW57_01240	COG1131	(ABC) transporter
EXW57_01245	COG0842	Transport permease protein
EXW57_01245	COG1511	domain protein
EXW57_01250	COG0842	Transport permease protein
EXW57_01260	COG0747	negative chemotaxis
EXW57_01270	COG0601	transmembrane transport
EXW57_01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW57_01280	COG0444	Belongs to the ABC transporter superfamily
EXW57_01285	COG4608	Belongs to the ABC transporter superfamily
EXW57_01290	COG0561	phosphatase activity
EXW57_01320	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW57_01325	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW57_01335	COG0531	amino acid
EXW57_01340	COG2814	Major facilitator Superfamily
EXW57_01350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW57_01360	COG4294	response to UV
EXW57_01365	COG0705	Rhomboid family
EXW57_01370	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW57_01375	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW57_01385	COG0864	Transcriptional regulator
EXW57_01390	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW57_01395	COG2183	response to ionizing radiation
EXW57_01495	COG0802	atpase or kinase
EXW57_01500	COG1214	PFAM Peptidase M22, glycoprotease
EXW57_01505	COG0456	acetyltransferase
EXW57_01515	COG0488	(ABC) transporter
EXW57_01520	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW57_01530	COG1266	CAAX protease self-immunity
EXW57_01535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW57_01540	COG0459	protein refolding
EXW57_01545	COG0519	Catalyzes the synthesis of GMP from XMP
EXW57_01545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW57_01550	COG2252	PERMEase
EXW57_01560	COG5002	protein histidine kinase activity
EXW57_01585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW57_01650	COG2205	protein histidine kinase activity
EXW57_01655	COG0745	RESPONSE REGULATOR receiver
EXW57_01680	COG0697	spore germination
EXW57_01710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW57_01715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW57_01720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW57_01725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW57_01730	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW57_01735	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW57_01740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW57_01745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW57_01750	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW57_01755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW57_01760	COG0138	bifunctional purine biosynthesis protein purh
EXW57_01770	COG0151	Belongs to the GarS family
EXW57_01790	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW57_01795	COG0210	DNA helicase
EXW57_01800	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW57_01805	COG4851	CamS sex pheromone cAM373 precursor
EXW57_01815	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_01820	COG1335	isochorismatase
EXW57_01830	COG2011	ABC-type metal ion transport system permease component
EXW57_01835	COG1464	Belongs to the NlpA lipoprotein family
EXW57_01850	COG0003	Pfam Anion-transporting ATPase
EXW57_01855	COG1846	Transcriptional regulator
EXW57_01860	COG4682	membrane
EXW57_01870	COG0154	amidase activity
EXW57_01875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW57_01880	COG1597	lipid kinase activity
EXW57_01885	COG0546	phosphoglycolate phosphatase activity
EXW57_01890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW57_01900	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_01905	COG2076	Multidrug Resistance protein
EXW57_01910	COG2309	aminopeptidase activity
EXW57_01925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_01935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW57_01940	COG5002	protein histidine kinase activity
EXW57_01945	COG4807	Protein conserved in bacteria
EXW57_01970	COG1757	Na H antiporter
EXW57_01975	COG1473	amidohydrolase
EXW57_01990	COG0450	alkyl hydroperoxide reductase
EXW57_02000	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW57_02010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_02015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_02020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_02030	COG0492	ferredoxin-NADP+ reductase activity
EXW57_02045	COG0166	Belongs to the GPI family
EXW57_02070	COG5002	protein histidine kinase activity
EXW57_02090	COG3541	Predicted nucleotidyltransferase
EXW57_02100	COG2814	Major facilitator Superfamily
EXW57_02105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW57_02105	COG0723	plastoquinol--plastocyanin reductase activity
EXW57_02115	COG0765	amino acid transport
EXW57_02120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW57_02130	COG0840	transmembrane signaling receptor activity
EXW57_02135	COG0277	FAD linked oxidase domain protein
EXW57_02140	COG0366	Alpha amylase catalytic
EXW57_02145	COG1263	PTS System
EXW57_02145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_02145	COG2190	(PTS) system
EXW57_02165	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW57_02170	COG0352	thiamine-phosphate diphosphorylase activity
EXW57_02175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW57_02190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW57_02195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW57_02200	COG1116	anion transmembrane transporter activity
EXW57_02205	COG0488	(ABC) transporter
EXW57_02250	COG2270	Major facilitator Superfamily
EXW57_02280	COG2310	stress, protein
EXW57_02285	COG2310	stress, protein
EXW57_02290	COG2310	stress, protein
EXW57_02295	COG0861	Integral membrane protein TerC family
EXW57_02305	COG3853	Toxic anion resistance protein (TelA)
EXW57_02315	COG4840	Belongs to the UPF0435 family
EXW57_02320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW57_02330	COG1295	ribonuclease BN
EXW57_02335	COG2217	Heavy metal translocating P-type atpase
EXW57_02340	COG0697	spore germination
EXW57_02365	COG0586	Pfam SNARE associated Golgi protein
EXW57_02380	COG3871	stress protein (general stress protein 26)
EXW57_02385	COG0387	Pfam Sodium calcium exchanger
EXW57_02395	COG0535	radical SAM domain protein
EXW57_02415	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW57_02435	COG3829	transcription factor binding
EXW57_02445	COG0833	amino acid
EXW57_02450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW57_02470	COG2066	Belongs to the glutaminase family
EXW57_02480	COG1263	PTS System
EXW57_02480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_02485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_02500	COG1216	Glycosyl transferase, family 2
EXW57_02510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW57_02510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW57_02515	COG0463	Glycosyl transferase, family 2
EXW57_02530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW57_02535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW57_02550	COG1228	amidohydrolase
EXW57_02555	COG1090	epimerase
EXW57_02560	COG2137	regulation of response to DNA damage stimulus
EXW57_02585	COG1988	membrane-bound metal-dependent
EXW57_02590	COG1194	a g-specific adenine glycosylase
EXW57_02605	COG3557	Belongs to the UPF0374 family
EXW57_02610	COG1132	(ABC) transporter
EXW57_02615	COG4129	membrane
EXW57_02625	COG0069	glutamate synthase activity
EXW57_02625	COG0070	glutamate synthase
EXW57_02625	COG0067	glutamate synthase
EXW57_02630	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW57_02635	COG4555	ABC transporter
EXW57_02655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW57_02660	COG0735	belongs to the Fur family
EXW57_02780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW57_02785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW57_02805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW57_02815	COG2766	serine protein kinase
EXW57_02820	COG2718	Belongs to the UPF0229 family
EXW57_02835	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW57_02840	COG2268	Band 7 protein
EXW57_02850	COG3290	protein histidine kinase activity
EXW57_02855	COG4565	transcriptional regulatory protein
EXW57_02860	COG2851	Citrate transporter
EXW57_02885	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW57_02890	COG3842	ATPase activity
EXW57_02895	COG1175	transmembrane transport
EXW57_02900	COG0395	ABC-type sugar transport system, permease component
EXW57_02910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW57_02915	COG0745	RESPONSE REGULATOR receiver
EXW57_02920	COG5002	protein histidine kinase activity
EXW57_02930	COG4990	cell redox homeostasis
EXW57_02940	COG3290	protein histidine kinase activity
EXW57_02945	COG4565	transcriptional regulatory protein
EXW57_02950	COG3493	citrate carrier protein
EXW57_02955	COG0281	malic enzyme
EXW57_02965	COG0697	spore germination
EXW57_02970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_02980	COG5002	protein histidine kinase activity
EXW57_02985	COG0745	RESPONSE REGULATOR receiver
EXW57_02990	COG0456	acetyltransferase
EXW57_02995	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW57_03000	COG3383	formate dehydrogenase (NAD+) activity
EXW57_03005	COG2427	Protein of unknown function (DUF1641)
EXW57_03020	COG0531	amino acid
EXW57_03030	COG0640	Transcriptional regulator
EXW57_03035	COG2217	Heavy metal translocating P-type atpase
EXW57_03040	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW57_03055	COG3227	Zinc metalloprotease (Elastase)
EXW57_03075	COG2720	vancomycin resistance protein
EXW57_03080	COG1316	TRANSCRIPTIONal
EXW57_03085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_03090	COG0346	lactoylglutathione lyase activity
EXW57_03095	COG1253	flavin adenine dinucleotide binding
EXW57_03100	COG1027	Aspartate ammonia-lyase
EXW57_03105	COG1620	l-lactate permease
EXW57_03110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW57_03130	COG3104	oligopeptide transport
EXW57_03135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_03145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_03160	COG0156	8-amino-7-oxononanoate synthase activity
EXW57_03165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW57_03175	COG4548	von Willebrand factor, type A
EXW57_03180	COG0714	Associated with various cellular activities
EXW57_03200	COG0531	amino acid
EXW57_03205	COG2188	Transcriptional regulator
EXW57_03210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_03210	COG1263	PTS System
EXW57_03215	COG0366	Alpha amylase catalytic
EXW57_03230	COG0697	spore germination
EXW57_03235	COG4585	Histidine kinase
EXW57_03240	COG2197	response regulator
EXW57_03245	COG1404	Belongs to the peptidase S8 family
EXW57_03260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW57_03265	COG1115	amino acid carrier protein
EXW57_03270	COG1126	abc transporter atp-binding protein
EXW57_03275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW57_03280	COG0765	amino acid transport
EXW57_03285	COG0765	amino acid transport
EXW57_03290	COG0833	amino acid
EXW57_03300	COG2378	regulation of single-species biofilm formation
EXW57_03305	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW57_03310	COG5002	protein histidine kinase activity
EXW57_03325	COG0659	secondary active sulfate transmembrane transporter activity
EXW57_03340	COG2271	Major facilitator Superfamily
EXW57_03345	COG1846	Transcriptional regulator
EXW57_03350	COG0477	Major facilitator Superfamily
EXW57_03355	COG1609	Transcriptional regulator
EXW57_03360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW57_03365	COG1869	D-ribose catabolic process
EXW57_03375	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW57_03380	COG1879	ABC-type sugar transport system periplasmic component
EXW57_03410	COG1063	alcohol dehydrogenase
EXW57_03425	COG3568	Endonuclease Exonuclease Phosphatase
EXW57_03455	COG0840	transmembrane signaling receptor activity
EXW57_03460	COG1388	LysM domain
EXW57_03460	COG3584	3D domain protein
EXW57_03465	COG1476	TRANSCRIPTIONal
EXW57_03485	COG3104	oligopeptide transport
EXW57_03490	COG1114	Component of the transport system for branched-chain amino acids
EXW57_03505	COG1113	amino acid transport
EXW57_03510	COG2252	PERMEase
EXW57_03525	COG2153	protein acetylation
EXW57_03535	COG0475	glutathione-regulated potassium exporter activity
EXW57_03535	COG0569	domain protein
EXW57_03550	COG1845	cytochrome c oxidase, subunit III
EXW57_03555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW57_03565	COG0833	amino acid
EXW57_03570	COG4990	cell redox homeostasis
EXW57_03585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW57_03590	COG0697	spore germination
EXW57_03595	COG0531	amino acid
EXW57_03605	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW57_03610	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW57_03620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW57_03625	COG0573	inorganic phosphate transmembrane transporter activity
EXW57_03630	COG0581	inorganic phosphate transmembrane transporter activity
EXW57_03640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW57_03760	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW57_03775	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_03775	COG3103	Sh3 type 3 domain protein
EXW57_03775	COG4991	sh3 domain protein
EXW57_03780	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW57_03785	COG1116	anion transmembrane transporter activity
EXW57_03790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW57_03795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW57_03800	COG0352	thiamine-phosphate diphosphorylase activity
EXW57_03805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW57_03810	COG2104	thiamine diphosphate biosynthetic process
EXW57_03815	COG2022	thiamine diphosphate biosynthetic process
EXW57_03820	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW57_03825	COG0351	phosphomethylpyrimidine kinase
EXW57_03850	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW57_03855	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW57_03860	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW57_03865	COG2205	protein histidine kinase activity
EXW57_03870	COG2814	Major facilitator Superfamily
EXW57_03875	COG1846	Transcriptional regulator
EXW57_03895	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW57_03900	COG1129	ABC transporter
EXW57_03905	COG1879	ABC-type sugar transport system periplasmic component
EXW57_03910	COG2252	PERMEase
EXW57_03915	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_03930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW57_03935	COG1621	beta-fructofuranosidase activity
EXW57_03940	COG1263	PTS System
EXW57_03940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_03945	COG1609	Transcriptional regulator
EXW57_03995	COG0778	Nitroreductase
EXW57_04000	COG2719	SpoVR family
EXW57_04025	COG1937	Protein conserved in bacteria
EXW57_04030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW57_04030	COG0425	Belongs to the sulfur carrier protein TusA family
EXW57_04035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_04035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW57_04040	COG0425	Belongs to the sulfur carrier protein TusA family
EXW57_04045	COG0425	Belongs to the sulfur carrier protein TusA family
EXW57_04045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW57_04050	COG2210	Belongs to the sulfur carrier protein TusA family
EXW57_04055	COG0730	response to heat
EXW57_04065	COG1316	TRANSCRIPTIONal
EXW57_04070	COG0604	alcohol dehydrogenase
EXW57_04075	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW57_04085	COG0604	alcohol dehydrogenase
EXW57_04090	COG2814	Major facilitator Superfamily
EXW57_04105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW57_04105	COG3711	transcriptional antiterminator
EXW57_04110	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW57_04115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW57_04140	COG3584	3D domain protein
EXW57_04140	COG1388	LysM domain
EXW57_04145	COG0577	efflux transmembrane transporter activity
EXW57_04150	COG1136	(ABC) transporter
EXW57_04160	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW57_04175	COG1114	Component of the transport system for branched-chain amino acids
EXW57_04180	COG3546	catalase activity
EXW57_04210	COG0586	Pfam SNARE associated Golgi protein
EXW57_04245	COG0531	amino acid
EXW57_04250	COG0475	glutathione-regulated potassium exporter activity
EXW57_04260	COG1737	Transcriptional regulator
EXW57_04265	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW57_04270	COG1263	PTS System
EXW57_04270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_04280	COG2259	Doxx family
EXW57_04300	COG0697	spore germination
EXW57_04305	COG1522	sequence-specific DNA binding
EXW57_04315	COG0300	oxidoreductase activity
EXW57_04330	COG2076	Multidrug Resistance protein
EXW57_04335	COG1309	transcriptional regulator
EXW57_04340	COG2814	Major facilitator Superfamily
EXW57_04345	COG1733	regulation of RNA biosynthetic process
EXW57_04360	COG4533	DNA binding
EXW57_04365	COG2211	Major facilitator Superfamily
EXW57_04375	COG0693	protein deglycase activity
EXW57_04385	COG0531	amino acid
EXW57_04390	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_04405	COG1132	(ABC) transporter
EXW57_04410	COG1132	(ABC) transporter
EXW57_04415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW57_04420	COG0765	amino acid transport
EXW57_04425	COG1126	abc transporter atp-binding protein
EXW57_04440	COG0189	ligase activity
EXW57_04450	COG4399	Belongs to the UPF0754 family
EXW57_04455	COG3679	Belongs to the UPF0342 family
EXW57_04470	COG0028	Belongs to the TPP enzyme family
EXW57_04475	COG3527	Alpha-acetolactate decarboxylase
EXW57_04480	COG0463	Glycosyl transferase, family 2
EXW57_04485	COG1216	Glycosyl transferase, family 2
EXW57_04490	COG2094	Belongs to the DNA glycosylase MPG family
EXW57_04495	COG0561	phosphatase activity
EXW57_04505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW57_04510	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_04520	COG0659	secondary active sulfate transmembrane transporter activity
EXW57_04535	COG0653	protein targeting
EXW57_04540	COG2244	polysaccharide biosynthetic process
EXW57_04550	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_04570	COG1696	Membrane protein involved in D-alanine export
EXW57_04585	COG1024	Enoyl-CoA hydratase
EXW57_04600	COG1363	Peptidase, m42
EXW57_04615	COG2318	DinB family
EXW57_04635	COG0579	oxidoreductase
EXW57_04670	COG0601	transmembrane transport
EXW57_04675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW57_04680	COG0444	Belongs to the ABC transporter superfamily
EXW57_04685	COG4608	Belongs to the ABC transporter superfamily
EXW57_04785	COG0582	viral genome integration into host DNA
EXW57_04880	COG0477	Major facilitator Superfamily
EXW57_04885	COG3290	protein histidine kinase activity
EXW57_04890	COG4565	transcriptional regulatory protein
EXW57_04895	COG3181	Tripartite tricarboxylate transporter family receptor
EXW57_04940	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EXW57_04965	COG0789	Transcriptional regulator
EXW57_04965	COG4978	Transcriptional regulator
EXW57_04980	COG0305	Participates in initiation and elongation during chromosome replication
EXW57_05010	COG0477	Major facilitator Superfamily
EXW57_05045	COG3711	transcriptional antiterminator
EXW57_05050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_05050	COG2190	(PTS) system
EXW57_05050	COG1263	PTS System
EXW57_05055	COG2723	6-phospho-beta-galactosidase activity
EXW57_05060	COG0456	acetyltransferase
EXW57_05070	COG1183	phosphatidylcholine synthase activity
EXW57_05130	COG2814	Major facilitator Superfamily
EXW57_05135	COG0640	Transcriptional regulator
EXW57_05155	COG2376	Dihydroxyacetone kinase
EXW57_05170	COG2376	Dihydroxyacetone kinase
EXW57_05185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW57_05200	COG1335	isochorismatase
EXW57_05225	COG0076	glutamate decarboxylase activity
EXW57_05250	COG0737	Belongs to the 5'-nucleotidase family
EXW57_05250	COG1525	nuclease
EXW57_05250	COG4085	toxin activity
EXW57_05265	COG0582	viral genome integration into host DNA
EXW57_05280	COG2378	regulation of single-species biofilm formation
EXW57_05285	COG2318	DinB family
EXW57_05290	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EXW57_05290	COG4932	domain protein
EXW57_05290	COG3266	domain, Protein
EXW57_05300	COG0825	malonyl-CoA metabolic process
EXW57_05320	COG3237	CsbD-like
EXW57_05340	COG2172	sigma factor antagonist activity
EXW57_05345	COG1191	sigma factor activity
EXW57_05355	COG2208	phosphoserine phosphatase activity
EXW57_05360	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW57_05365	COG2205	protein histidine kinase activity
EXW57_05365	COG0784	Response regulator, receiver
EXW57_05365	COG5002	protein histidine kinase activity
EXW57_05405	COG2807	transmembrane transport
EXW57_05410	COG2186	Transcriptional regulator
EXW57_05415	COG4585	Histidine kinase
EXW57_05420	COG2197	response regulator
EXW57_05450	COG0420	3'-5' exonuclease activity
EXW57_05455	COG4717	serine-type aminopeptidase activity
EXW57_05460	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW57_05470	COG0346	lactoylglutathione lyase activity
EXW57_05485	COG2267	carboxylic ester hydrolase activity
EXW57_05500	COG3620	sequence-specific DNA binding
EXW57_05505	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW57_05510	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW57_05515	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW57_05520	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW57_05525	COG1595	DNA-templated transcription, initiation
EXW57_05540	COG3973	AAA domain
EXW57_05545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW57_05560	COG1846	Transcriptional regulator
EXW57_05570	COG0537	adenosine 5'-monophosphoramidase activity
EXW57_05575	COG1131	(ABC) transporter
EXW57_05580	COG4473	ABC transporter
EXW57_05590	COG0247	lactate metabolic process
EXW57_05595	COG1139	Iron-sulfur cluster binding protein
EXW57_05600	COG1556	Lactate utilization protein
EXW57_05615	COG3402	PFAM membrane-flanked domain
EXW57_05620	COG3428	Bacterial PH domain
EXW57_05650	COG3402	PFAM membrane-flanked domain
EXW57_05655	COG3428	Bacterial PH domain
EXW57_05660	COG2329	Antibiotic biosynthesis monooxygenase
EXW57_05665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW57_05670	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW57_05675	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW57_05680	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW57_05705	COG1309	transcriptional regulator
EXW57_05710	COG1511	domain protein
EXW57_05745	COG2378	regulation of single-species biofilm formation
EXW57_05750	COG1609	Transcriptional regulator
EXW57_05760	COG1234	tRNA 3'-trailer cleavage
EXW57_05765	COG0095	Lipoate-protein ligase
EXW57_05775	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_05790	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW57_05795	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW57_05800	COG4208	sulfate ABC transporter
EXW57_05815	COG1408	metallophosphoesterase
EXW57_05820	COG1078	dGTPase activity
EXW57_05835	COG1595	DNA-templated transcription, initiation
EXW57_05845	COG2207	Transcriptional regulator
EXW57_05845	COG3708	Transcriptional regulator
EXW57_05850	COG2205	protein histidine kinase activity
EXW57_05855	COG0745	RESPONSE REGULATOR receiver
EXW57_05875	COG0501	Belongs to the peptidase M48B family
EXW57_05880	COG0697	spore germination
EXW57_05910	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW57_05915	COG2224	Isocitrate lyase
EXW57_05925	COG1278	Cold shock
EXW57_05945	COG4903	ComK protein
EXW57_05950	COG0398	Pfam SNARE associated Golgi protein
EXW57_05960	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW57_05965	COG1074	ATP-dependent DNA helicase activity
EXW57_06015	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW57_06040	COG0367	asparagine synthase
EXW57_06050	COG0753	catalase activity
EXW57_06055	COG0004	ammonium transporteR
EXW57_06065	COG1666	GTP binding
EXW57_06070	COG2996	Protein conserved in bacteria
EXW57_06075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW57_06085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_06100	COG0561	phosphatase activity
EXW57_06120	COG2267	carboxylic ester hydrolase activity
EXW57_06135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW57_06140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW57_06145	COG5504	Zn-dependent protease
EXW57_06160	COG0180	Tryptophanyl-tRNA synthetase
EXW57_06175	COG4166	transmembrane transport
EXW57_06180	COG0601	transmembrane transport
EXW57_06185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW57_06190	COG0444	Belongs to the ABC transporter superfamily
EXW57_06195	COG4608	Belongs to the ABC transporter superfamily
EXW57_06200	COG0534	Mate efflux family protein
EXW57_06205	COG4166	transmembrane transport
EXW57_06225	COG0861	Integral membrane protein TerC family
EXW57_06230	COG4862	establishment of competence for transformation
EXW57_06235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW57_06245	COG1164	Oligoendopeptidase f
EXW57_06255	COG2346	COG2346, Truncated hemoglobins
EXW57_06260	COG4116	CYTH
EXW57_06270	COG2357	RelA SpoT domain protein
EXW57_06280	COG0564	pseudouridine synthase activity
EXW57_06290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW57_06295	COG0772	Belongs to the SEDS family
EXW57_06300	COG1216	Glycosyl transferase, family 2
EXW57_06320	COG0457	Tetratricopeptide repeat
EXW57_06320	COG0463	Glycosyl transferase, family 2
EXW57_06340	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW57_06355	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW57_06400	COG2153	protein acetylation
EXW57_06405	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW57_06410	COG2382	esterase
EXW57_06435	COG5492	domain, Protein
EXW57_06440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW57_06455	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW57_06455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW57_06460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW57_06465	COG0134	indole-3-glycerol-phosphate synthase activity
EXW57_06470	COG0135	phosphoribosylanthranilate isomerase activity
EXW57_06475	COG0133	tryptophan synthase activity
EXW57_06480	COG0159	tryptophan synthase activity
EXW57_06490	COG1620	l-lactate permease
EXW57_06495	COG5634	Uncharacterized conserved protein (DUF2278)
EXW57_06530	COG2226	methyltransferase
EXW57_06550	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW57_06555	COG0567	Dehydrogenase, E1 component
EXW57_06560	COG1476	TRANSCRIPTIONal
EXW57_06665	COG0582	viral genome integration into host DNA
EXW57_06685	COG1686	Belongs to the peptidase S11 family
EXW57_06690	COG0681	Belongs to the peptidase S26 family
EXW57_06725	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_06735	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW57_06740	COG1177	transmembrane transport
EXW57_06745	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW57_06755	COG2409	Drug exporters of the RND superfamily
EXW57_06765	COG0564	pseudouridine synthase activity
EXW57_06775	COG2340	Cysteine-rich secretory protein family
EXW57_06780	COG0247	lactate metabolic process
EXW57_06785	COG0277	FAD linked oxidase domain protein
EXW57_06790	COG3835	regulator
EXW57_06800	COG0745	RESPONSE REGULATOR receiver
EXW57_06805	COG5002	protein histidine kinase activity
EXW57_06810	COG2186	Transcriptional regulator
EXW57_06815	COG0247	lactate metabolic process
EXW57_06820	COG1139	Iron-sulfur cluster binding protein
EXW57_06825	COG1556	Lactate utilization protein
EXW57_06830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW57_06840	COG2116	formate transmembrane transporter activity
EXW57_06845	COG0861	Integral membrane protein TerC family
EXW57_06850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW57_06860	COG2030	dehydratase
EXW57_06880	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_06885	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW57_06895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW57_06910	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW57_06915	COG3842	ATPase activity
EXW57_06925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW57_06930	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW57_06940	COG1349	DNA-binding transcription factor activity
EXW57_06950	COG0235	Class ii aldolase
EXW57_06960	COG2861	carbohydrate metabolic process
EXW57_06970	COG3852	Histidine kinase
EXW57_06975	COG1846	Transcriptional regulator
EXW57_06985	COG2318	DinB family
EXW57_06990	COG5002	protein histidine kinase activity
EXW57_06995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW57_07000	COG0720	synthase
EXW57_07010	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW57_07015	COG4873	Protein conserved in bacteria
EXW57_07025	COG0456	acetyltransferase
EXW57_07045	COG1780	Probably involved in ribonucleotide reductase function
EXW57_07060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW57_07065	COG0531	amino acid
EXW57_07070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW57_07085	COG2204	response regulator
EXW57_07090	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_07100	COG1725	Transcriptional regulator
EXW57_07105	COG1131	(ABC) transporter
EXW57_07115	COG1131	(ABC) transporter
EXW57_07120	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW57_07125	COG1266	CAAX protease self-immunity
EXW57_07135	COG1522	sequence-specific DNA binding
EXW57_07145	COG1335	isochorismatase
EXW57_07155	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW57_07160	COG2070	2-Nitropropane dioxygenase
EXW57_07165	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW57_07170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW57_07175	COG1696	Membrane protein involved in D-alanine export
EXW57_07195	COG0716	FMN binding
EXW57_07220	COG0534	Mate efflux family protein
EXW57_07225	COG1968	undecaprenyl-diphosphatase activity
EXW57_07245	COG1846	Transcriptional regulator
EXW57_07255	COG1301	dicarboxylic acid transport
EXW57_07270	COG3874	Sporulation protein YtfJ
EXW57_07290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW57_07295	COG0028	Belongs to the TPP enzyme family
EXW57_07300	COG0440	acetolactate synthase activity
EXW57_07310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW57_07320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW57_07330	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW57_07335	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW57_07345	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW57_07350	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW57_07355	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW57_07360	COG0107	imidazoleglycerol-phosphate synthase activity
EXW57_07370	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW57_07375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW57_07390	COG1183	phosphatidylcholine synthase activity
EXW57_07395	COG1368	sulfuric ester hydrolase activity
EXW57_07405	COG0019	diaminopimelate decarboxylase activity
EXW57_07415	COG0175	sulfate reduction
EXW57_07420	COG2046	Belongs to the sulfate adenylyltransferase family
EXW57_07425	COG0529	Catalyzes the synthesis of activated sulfate
EXW57_07430	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW57_07450	COG1648	precorrin-2 dehydrogenase activity
EXW57_07460	COG0733	neurotransmitter:sodium symporter activity
EXW57_07480	COG1757	Na H antiporter
EXW57_07495	COG4758	membrane
EXW57_07500	COG4585	Histidine kinase
EXW57_07505	COG2197	response regulator
EXW57_07515	COG1114	Component of the transport system for branched-chain amino acids
EXW57_07525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW57_07570	COG0730	response to heat
EXW57_07575	COG0306	phosphate transporter
EXW57_07580	COG1392	Phosphate transport regulator
EXW57_07585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW57_07600	COG3852	Histidine kinase
EXW57_07605	COG1801	Protein of unknown function DUF72
EXW57_07615	COG0582	viral genome integration into host DNA
EXW57_07620	COG5002	protein histidine kinase activity
EXW57_07635	COG0392	lysyltransferase activity
EXW57_07635	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW57_07650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW57_07655	COG1686	Belongs to the peptidase S11 family
EXW57_07660	COG2715	membrane protein required for spore maturation
EXW57_07665	COG0700	Nucleoside recognition
EXW57_07670	COG1187	pseudouridine synthase activity
EXW57_07680	COG1333	cytochrome c biogenesis protein
EXW57_07685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW57_07690	COG0745	RESPONSE REGULATOR receiver
EXW57_07695	COG5002	protein histidine kinase activity
EXW57_07700	COG2096	Adenosyltransferase
EXW57_07705	COG4942	peptidase
EXW57_07715	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW57_07720	COG1141	Ferredoxin
EXW57_07730	COG4955	Helix-turn-helix domain
EXW57_07735	COG0514	ATP-dependent DNA helicase (RecQ)
EXW57_07740	COG1266	CAAX protease self-immunity
EXW57_07750	COG1408	metallophosphoesterase
EXW57_07765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW57_07785	COG0492	ferredoxin-NADP+ reductase activity
EXW57_07790	COG0252	asparaginase activity
EXW57_07795	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW57_07805	COG1304	FMN binding
EXW57_07840	COG1160	GTP binding
EXW57_07845	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW57_07865	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW57_07875	COG0302	gtp cyclohydrolase
EXW57_07880	COG0142	geranyltranstransferase activity
EXW57_07885	COG2226	methyltransferase
EXW57_07890	COG0142	geranyltranstransferase activity
EXW57_07905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW57_07915	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW57_07920	COG0457	Tetratricopeptide repeat
EXW57_07925	COG5582	Belongs to the UPF0302 family
EXW57_07940	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW57_07960	COG4347	Protein of unknown function (DUF1405)
EXW57_07975	COG2738	Putative neutral zinc metallopeptidase
EXW57_07985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_07995	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW57_08000	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW57_08005	COG1803	Methylglyoxal synthase
EXW57_08010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW57_08015	COG0438	transferase activity, transferring glycosyl groups
EXW57_08020	COG0617	tRNA 3'-terminal CCA addition
EXW57_08030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW57_08035	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW57_08045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW57_08045	COG1199	ATP-dependent helicase activity
EXW57_08065	COG3935	DnaD domain protein
EXW57_08070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW57_08080	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW57_08080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW57_08085	COG3331	DNA recombination
EXW57_08120	COG4474	Belongs to the UPF0398 family
EXW57_08125	COG3599	regulation of cell shape
EXW57_08135	COG0116	Belongs to the methyltransferase superfamily
EXW57_08145	COG1199	ATP-dependent helicase activity
EXW57_08150	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW57_08160	COG0024	Methionine aminopeptidase
EXW57_08170	COG2233	PERMEase
EXW57_08175	COG2311	Membrane
EXW57_08180	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW57_08190	COG0456	acetyltransferase
EXW57_08200	COG2897	thiosulfate sulfurtransferase activity
EXW57_08240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW57_08255	COG0454	-acetyltransferase
EXW57_08275	COG0328	RNA-DNA hybrid ribonuclease activity
EXW57_08310	COG3403	YqcI/YcgG family
EXW57_08315	COG1280	lysine exporter protein (LysE YggA)
EXW57_08330	COG3162	membrane
EXW57_08335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW57_08340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW57_08350	COG0475	glutathione-regulated potassium exporter activity
EXW57_08355	COG0789	Transcriptional regulator
EXW57_08355	COG4978	Transcriptional regulator
EXW57_08365	COG2323	membrane
EXW57_08370	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW57_08400	COG2814	Major facilitator Superfamily
EXW57_08420	COG1923	regulation of RNA biosynthetic process
EXW57_08430	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW57_08435	COG1360	Flagellar Motor Protein
EXW57_08440	COG2201	protein-glutamate methylesterase activity
EXW57_08445	COG0643	Histidine kinase
EXW57_08445	COG2198	Histidine kinase
EXW57_08450	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW57_08450	COG1776	CheC inhibitor of MCP methylation
EXW57_08465	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW57_08485	COG1256	bacterial-type flagellum assembly
EXW57_08490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW57_08515	COG1815	bacterial-type flagellum-dependent cell motility
EXW57_08520	COG1558	bacterial-type flagellum-dependent cell motility
EXW57_08530	COG1766	The M ring may be actively involved in energy transduction
EXW57_08535	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW57_08545	COG1157	protein secretion by the type III secretion system
EXW57_08565	COG1749	Flagellar hook protein flgE
EXW57_08580	COG0835	chemotaxis
EXW57_08580	COG0784	Response regulator, receiver
EXW57_08605	COG0861	Integral membrane protein TerC family
EXW57_08615	COG3383	formate dehydrogenase (NAD+) activity
EXW57_08620	COG2427	Protein of unknown function (DUF1641)
EXW57_08625	COG5609	conserved protein (DUF2294)
EXW57_08630	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW57_08640	COG2116	formate transmembrane transporter activity
EXW57_08645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW57_08650	COG0303	'Molybdopterin
EXW57_08655	COG0314	molybdopterin synthase activity
EXW57_08660	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW57_08670	COG0489	protein tyrosine kinase activity
EXW57_08675	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW57_08675	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW57_08680	COG0741	lytic transglycosylase activity
EXW57_08690	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW57_08695	COG1776	CheC inhibitor of MCP methylation
EXW57_08695	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW57_08705	COG1338	Plays a role in the flagellum-specific transport system
EXW57_08710	COG1987	bacterial-type flagellum assembly
EXW57_08720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW57_08725	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW57_08730	COG1419	protein localization to endoplasmic reticulum
EXW57_08735	COG4786	Flagellar basal body rod
EXW57_08770	COG0412	Dienelactone hydrolase
EXW57_08775	COG2329	Antibiotic biosynthesis monooxygenase
EXW57_08790	COG2814	Major facilitator Superfamily
EXW57_08800	COG0583	DNA-binding transcription factor activity
EXW57_08805	COG3842	ATPase activity
EXW57_08855	COG0406	alpha-ribazole phosphatase activity
EXW57_08885	COG0367	asparagine synthase
EXW57_08915	COG1802	Transcriptional regulator
EXW57_08920	COG0697	spore germination
EXW57_08935	COG1216	Glycosyl transferase, family 2
EXW57_08935	COG0438	transferase activity, transferring glycosyl groups
EXW57_08940	COG1757	Na H antiporter
EXW57_08950	COG0277	FAD linked oxidase domain protein
EXW57_08970	COG0534	Mate efflux family protein
EXW57_08975	COG3340	Belongs to the peptidase S51 family
EXW57_08995	COG0785	Cytochrome C biogenesis protein
EXW57_09000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW57_09010	COG1917	Cupin 2, conserved barrel domain protein
EXW57_09015	COG3048	D-serine ammonia-lyase activity
EXW57_09020	COG2733	membrane
EXW57_09060	COG1131	(ABC) transporter
EXW57_09075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW57_09080	COG0528	UMP kinase activity
EXW57_09090	COG1027	Aspartate ammonia-lyase
EXW57_09095	COG0281	malic enzyme
EXW57_09100	COG4191	Histidine kinase
EXW57_09105	COG0784	Response regulator, receiver
EXW57_09110	COG1846	Transcriptional regulator
EXW57_09120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW57_09135	COG2502	aspartate--ammonia ligase
EXW57_09175	COG1051	belongs to the nudix hydrolase family
EXW57_09180	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_09190	COG2814	Major facilitator Superfamily
EXW57_09215	COG1695	Transcriptional regulator
EXW57_09225	COG2814	Major facilitator Superfamily
EXW57_09230	COG0640	Transcriptional regulator
EXW57_09235	COG0477	Major facilitator Superfamily
EXW57_09240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW57_09250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW57_09255	COG2223	nitrite transmembrane transporter activity
EXW57_09260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW57_09275	COG2244	polysaccharide biosynthetic process
EXW57_09280	COG0733	neurotransmitter:sodium symporter activity
EXW57_09290	COG5566	PFAM Mor transcription activator
EXW57_09295	COG2323	membrane
EXW57_09310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW57_09320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW57_09325	COG0028	Belongs to the TPP enzyme family
EXW57_09340	COG0129	dihydroxy-acid dehydratase activity
EXW57_09345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW57_09370	COG2814	Major facilitator Superfamily
EXW57_09375	COG3384	dioxygenase
EXW57_09400	COG4166	transmembrane transport
EXW57_09435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_09455	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW57_09460	COG1054	Belongs to the UPF0176 family
EXW57_09470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW57_09475	COG0531	amino acid
EXW57_09510	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW57_09525	COG4257	antibiotic catabolic process
EXW57_09530	COG2390	Transcriptional regulator
EXW57_09540	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW57_09545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_09550	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW57_09565	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW57_09580	COG0583	DNA-binding transcription factor activity
EXW57_09600	COG0006	proline dipeptidase activity
EXW57_09605	COG2132	Multicopper oxidase
EXW57_09620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW57_09630	COG0583	DNA-binding transcription factor activity
EXW57_09650	COG1114	Component of the transport system for branched-chain amino acids
EXW57_09660	COG1276	copper resistance
EXW57_09660	COG2372	response to copper ion
EXW57_09665	COG4549	nuclear export factor GLE1
EXW57_09675	COG0697	spore germination
EXW57_09680	COG0583	DNA-binding transcription factor activity
EXW57_09685	COG1959	2 iron, 2 sulfur cluster binding
EXW57_09690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW57_09695	COG0778	Nitroreductase
EXW57_09720	COG0628	permease
EXW57_09735	COG1231	oxidoreductase activity
EXW57_09740	COG0523	cobalamin synthesis protein
EXW57_09750	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_09755	COG2030	dehydratase
EXW57_09760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW57_09775	COG0411	ABC transporter
EXW57_09795	COG0583	DNA-binding transcription factor activity
EXW57_09805	COG1942	4-Oxalocrotonate Tautomerase
EXW57_09820	COG0346	lactoylglutathione lyase activity
EXW57_09830	COG1271	oxidase subunit
EXW57_09835	COG1294	oxidase, subunit
EXW57_09840	COG4988	ABC transporter
EXW57_09845	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW57_09875	COG1686	Belongs to the peptidase S11 family
EXW57_09890	COG0791	NLP P60 protein
EXW57_09890	COG1388	LysM domain
EXW57_09900	COG1132	(ABC) transporter
EXW57_09905	COG0745	RESPONSE REGULATOR receiver
EXW57_09910	COG5002	protein histidine kinase activity
EXW57_09915	COG0300	oxidoreductase activity
EXW57_09920	COG4122	O-methyltransferase activity
EXW57_09950	COG0460	homoserine dehydrogenase
EXW57_09960	COG0083	homoserine kinase activity
EXW57_09975	COG1316	TRANSCRIPTIONal
EXW57_10000	COG1285	pathogenesis
EXW57_10005	COG1247	-acetyltransferase
EXW57_10025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW57_10035	COG1082	Xylose isomerase domain protein TIM barrel
EXW57_10045	COG2814	Major facilitator Superfamily
EXW57_10050	COG1279	arginine transmembrane transporter activity
EXW57_10055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_10065	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW57_10095	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW57_10100	COG0577	efflux transmembrane transporter activity
EXW57_10105	COG2002	toxin-antitoxin pair type II binding
EXW57_10110	COG1404	Belongs to the peptidase S8 family
EXW57_10115	COG0640	Transcriptional regulator
EXW57_10120	COG0667	Aldo Keto reductase
EXW57_10125	COG2814	Major facilitator Superfamily
EXW57_10170	COG3949	Membrane
EXW57_10175	COG0783	Belongs to the Dps family
EXW57_10190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW57_10200	COG1231	oxidoreductase activity
EXW57_10205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_10210	COG4989	oxidoreductase activity
EXW57_10215	COG0523	cobalamin synthesis protein
EXW57_10220	COG0456	acetyltransferase
EXW57_10225	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW57_10245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW57_10255	COG4166	transmembrane transport
EXW57_10260	COG0346	lactoylglutathione lyase activity
EXW57_10270	COG0406	alpha-ribazole phosphatase activity
EXW57_10280	COG5337	Spore coat protein CotH
EXW57_10285	COG1051	belongs to the nudix hydrolase family
EXW57_10290	COG0586	Pfam SNARE associated Golgi protein
EXW57_10295	COG2244	polysaccharide biosynthetic process
EXW57_10305	COG0701	Predicted permease
EXW57_10310	COG3689	TIGRFAM TIGR03943 family protein
EXW57_10315	COG1607	acyl-coa hydrolase
EXW57_10325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW57_10345	COG0702	epimerase
EXW57_10350	COG2839	Protein conserved in bacteria
EXW57_10355	COG1253	flavin adenine dinucleotide binding
EXW57_10370	COG1114	Component of the transport system for branched-chain amino acids
EXW57_10375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW57_10395	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_10410	COG1876	peptidase activity
EXW57_10440	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_10450	COG0561	phosphatase activity
EXW57_10460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW57_10485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_10490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_10515	COG0456	acetyltransferase
EXW57_10550	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW57_10630	COG3874	Sporulation protein YtfJ
EXW57_10655	COG2226	methyltransferase
EXW57_10690	COG1595	DNA-templated transcription, initiation
EXW57_10725	COG0386	Belongs to the glutathione peroxidase family
EXW57_10730	COG1305	Transglutaminase-like
EXW57_10735	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW57_10740	COG0714	Associated with various cellular activities
EXW57_10745	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW57_10750	COG1140	nitrate reductase beta subunit
EXW57_10755	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW57_10760	COG2181	nitrate reductase activity
EXW57_10765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW57_10770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW57_10775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW57_10780	COG0303	'Molybdopterin
EXW57_10785	COG0314	molybdopterin synthase activity
EXW57_10795	COG2223	nitrite transmembrane transporter activity
EXW57_10815	COG1648	precorrin-2 dehydrogenase activity
EXW57_10825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW57_10825	COG1587	Uroporphyrinogen-III synthase
EXW57_10830	COG2146	nitrite reductase [NAD(P)H] activity
EXW57_10835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW57_10840	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW57_10870	COG2359	stage V sporulation protein S
EXW57_10915	COG1418	mRNA catabolic process
EXW57_10920	COG0488	(ABC) transporter
EXW57_10940	COG1413	lyase activity
EXW57_10955	COG2521	methyltransferase
EXW57_10955	COG2136	Putative SAM-dependent methyltransferase
EXW57_10960	COG0018	arginyl-trna synthetase
EXW57_11020	COG0017	Asparaginyl-tRNA synthetase
EXW57_11025	COG0733	neurotransmitter:sodium symporter activity
EXW57_11050	COG2610	gluconate transmembrane transporter activity
EXW57_11060	COG1794	racemase activity, acting on amino acids and derivatives
EXW57_11070	COG0456	acetyltransferase
EXW57_11075	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW57_11085	COG1131	(ABC) transporter
EXW57_11090	COG4473	ABC transporter
EXW57_11100	COG0546	phosphoglycolate phosphatase activity
EXW57_11115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_11130	COG0768	penicillin binding
EXW57_11140	COG0204	Acyl-transferase
EXW57_11145	COG1272	protein, Hemolysin III
EXW57_11150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW57_11155	COG0805	protein transport
EXW57_11170	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW57_11175	COG1999	signal sequence binding
EXW57_11180	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW57_11185	COG0367	asparagine synthase
EXW57_11200	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_11205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_11210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW57_11230	COG1335	isochorismatase
EXW57_11240	COG0668	transmembrane transport
EXW57_11245	COG4585	Histidine kinase
EXW57_11245	COG2203	Gaf domain
EXW57_11250	COG2197	response regulator
EXW57_11255	COG1737	Transcriptional regulator
EXW57_11260	COG1064	alcohol dehydrogenase
EXW57_11275	COG1070	Carbohydrate kinase
EXW57_11285	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW57_11305	COG1125	glycine betaine transport
EXW57_11305	COG0517	IMP dehydrogenase activity
EXW57_11310	COG1174	glycine betaine transport
EXW57_11345	COG1253	flavin adenine dinucleotide binding
EXW57_11350	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_11355	COG5506	Protein of unknown function (DUF1694)
EXW57_11370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW57_11375	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW57_11380	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW57_11385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW57_11390	COG0456	acetyltransferase
EXW57_11395	COG3829	transcription factor binding
EXW57_11400	COG1509	lysine 2,3-aminomutase activity
EXW57_11410	COG4479	Belongs to the UPF0346 family
EXW57_11435	COG4991	sh3 domain protein
EXW57_11435	COG3064	Membrane
EXW57_11435	COG0515	serine threonine protein kinase
EXW57_11445	COG0671	phosphoesterase, PA-phosphatase related
EXW57_11450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW57_11455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW57_11510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW57_11540	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_11560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW57_11560	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW57_11580	COG0372	Belongs to the citrate synthase family
EXW57_11585	COG2079	MmgE PrpD family protein
EXW57_11590	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW57_11595	COG1960	acyl-CoA dehydrogenase activity
EXW57_11600	COG2084	Dehydrogenase
EXW57_11605	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_11610	COG1280	lysine exporter protein (LysE YggA)
EXW57_11615	COG1024	Enoyl-CoA hydratase
EXW57_11630	COG0420	3'-5' exonuclease activity
EXW57_11650	COG2223	nitrite transmembrane transporter activity
EXW57_11655	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_11660	COG1169	isochorismate synthase
EXW57_11665	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW57_11670	COG1535	isochorismatase
EXW57_11670	COG3433	isochorismatase activity
EXW57_11675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW57_11680	COG3251	PFAM MbtH domain protein
EXW57_11685	COG2814	Major facilitator Superfamily
EXW57_11700	COG0776	regulation of translation
EXW57_11710	COG2318	DinB family
EXW57_11715	COG1115	amino acid carrier protein
EXW57_11730	COG2329	Antibiotic biosynthesis monooxygenase
EXW57_11745	COG1187	pseudouridine synthase activity
EXW57_11750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW57_11755	COG3655	Transcriptional regulator
EXW57_11765	COG1136	(ABC) transporter
EXW57_11775	COG0596	Alpha beta hydrolase
EXW57_11790	COG0028	Belongs to the TPP enzyme family
EXW57_11815	COG1253	flavin adenine dinucleotide binding
EXW57_11845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW57_11865	COG1846	Transcriptional regulator
EXW57_11875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_11880	COG1309	transcriptional regulator
EXW57_11910	COG1247	-acetyltransferase
EXW57_11950	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW57_11960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_11990	COG0583	DNA-binding transcription factor activity
EXW57_11995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW57_12010	COG0583	DNA-binding transcription factor activity
EXW57_12015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW57_12020	COG2258	MOSC domain
EXW57_12035	COG1132	(ABC) transporter
EXW57_12040	COG1132	(ABC) transporter
EXW57_12055	COG0189	ligase activity
EXW57_12080	COG1396	sequence-specific DNA binding
EXW57_12115	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW57_12120	COG1595	DNA-templated transcription, initiation
EXW57_12200	COG2755	lipolytic protein G-D-S-L family
EXW57_12200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW57_12210	COG2169	Transcriptional regulator
EXW57_12220	COG0673	inositol 2-dehydrogenase activity
EXW57_12260	COG1649	PFAM Uncharacterised BCR, COG1649
EXW57_12280	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW57_12285	COG2971	BadF BadG BcrA BcrD
EXW57_12295	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW57_12345	COG1309	transcriptional regulator
EXW57_12360	COG1136	(ABC) transporter
EXW57_12365	COG0500	methyltransferase
EXW57_12365	COG3615	Tellurite resistance protein tehB
EXW57_12375	COG0693	protein deglycase activity
EXW57_12385	COG0588	phosphoglycerate mutase activity
EXW57_12405	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW57_12410	COG0110	maltose O-acetyltransferase activity
EXW57_12425	COG1136	(ABC) transporter
EXW57_12455	COG1136	(ABC) transporter
EXW57_12460	COG0577	efflux transmembrane transporter activity
EXW57_12485	COG1686	Belongs to the peptidase S11 family
EXW57_12510	COG0768	penicillin binding
EXW57_12515	COG0745	RESPONSE REGULATOR receiver
EXW57_12520	COG2205	protein histidine kinase activity
EXW57_12525	COG1136	(ABC) transporter
EXW57_12530	COG0577	efflux transmembrane transporter activity
EXW57_12540	COG1595	DNA-templated transcription, initiation
EXW57_12550	COG0768	penicillin binding
EXW57_12555	COG0768	penicillin binding
EXW57_12590	COG1252	NADH dehydrogenase
EXW57_12595	COG0425	Belongs to the sulfur carrier protein TusA family
EXW57_12595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW57_12610	COG0697	spore germination
EXW57_12635	COG3397	chitin binding
EXW57_12640	COG0823	Involved in the tonB-independent uptake of proteins
EXW57_12650	COG1408	metallophosphoesterase
EXW57_12660	COG1131	(ABC) transporter
EXW57_12670	COG1309	transcriptional regulator
EXW57_12680	COG1960	acyl-CoA dehydrogenase activity
EXW57_12685	COG0439	Biotin carboxylase
EXW57_12690	COG0511	ligase activity, forming carbon-carbon bonds
EXW57_12695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW57_12700	COG1024	Enoyl-CoA hydratase
EXW57_12705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW57_12710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW57_12755	COG2318	DinB family
EXW57_12785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW57_12815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW57_12845	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_12850	COG1733	regulation of RNA biosynthetic process
EXW57_12875	COG1309	transcriptional regulator
EXW57_12905	COG0697	spore germination
EXW57_12910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_12945	COG2323	membrane
EXW57_12960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_12965	COG0697	spore germination
EXW57_12985	COG0201	protein transport
EXW57_12995	COG0737	Belongs to the 5'-nucleotidase family
EXW57_13000	COG3227	Zinc metalloprotease (Elastase)
EXW57_13005	COG1523	belongs to the glycosyl hydrolase 13 family
EXW57_13020	COG0076	glutamate decarboxylase activity
EXW57_13025	COG0657	acetylesterase activity
EXW57_13035	COG1073	alpha beta
EXW57_13045	COG0577	efflux transmembrane transporter activity
EXW57_13050	COG1136	(ABC) transporter
EXW57_13080	COG5002	protein histidine kinase activity
EXW57_13085	COG0745	RESPONSE REGULATOR receiver
EXW57_13090	COG1011	Hydrolase
EXW57_13115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW57_13120	COG1183	phosphatidylcholine synthase activity
EXW57_13130	COG1132	(ABC) transporter
EXW57_13140	COG3961	Belongs to the TPP enzyme family
EXW57_13160	COG0322	excinuclease ABC activity
EXW57_13185	COG2318	DinB family
EXW57_13200	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW57_13225	COG3878	Protein conserved in bacteria
EXW57_13250	COG1051	belongs to the nudix hydrolase family
EXW57_13255	COG0592	DNA-directed DNA polymerase activity
EXW57_13260	COG2816	NAD+ diphosphatase activity
EXW57_13270	COG2223	nitrite transmembrane transporter activity
EXW57_13275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_13305	COG0697	spore germination
EXW57_13310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_13320	COG0584	glycerophosphoryl diester phosphodiesterase
EXW57_13335	COG2814	Major facilitator Superfamily
EXW57_13375	COG0768	penicillin binding
EXW57_13380	COG0671	phosphoesterase, PA-phosphatase related
EXW57_13385	COG0604	alcohol dehydrogenase
EXW57_13390	COG5002	protein histidine kinase activity
EXW57_13395	COG0745	RESPONSE REGULATOR receiver
EXW57_13405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW57_13415	COG2205	protein histidine kinase activity
EXW57_13430	COG1122	ATPase activity
EXW57_13435	COG4720	Psort location CytoplasmicMembrane, score
EXW57_13440	COG1794	racemase activity, acting on amino acids and derivatives
EXW57_13445	COG1819	glycosyl
EXW57_13455	COG0768	penicillin binding
EXW57_13460	COG5002	protein histidine kinase activity
EXW57_13465	COG0561	phosphatase activity
EXW57_13515	COG2124	cytochrome p450
EXW57_13560	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW57_13570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_13575	COG0460	homoserine dehydrogenase
EXW57_13595	COG0577	efflux transmembrane transporter activity
EXW57_13600	COG1136	(ABC) transporter
EXW57_13610	COG0488	(ABC) transporter
EXW57_13615	COG0667	Aldo Keto reductase
EXW57_13620	COG0583	DNA-binding transcription factor activity
EXW57_13625	COG2205	protein histidine kinase activity
EXW57_13630	COG0745	RESPONSE REGULATOR receiver
EXW57_13645	COG3773	Cell wall hydrolase
EXW57_13650	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW57_13700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_13715	COG2959	enzyme of heme biosynthesis
EXW57_13745	COG3483	tryptophan 2,3-dioxygenase activity
EXW57_13750	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW57_13755	COG3844	kynureninase activity
EXW57_13760	COG1309	transcriptional regulator
EXW57_13775	COG3284	Transcriptional regulator
EXW57_13790	COG1349	DNA-binding transcription factor activity
EXW57_13810	COG1959	2 iron, 2 sulfur cluster binding
EXW57_13825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW57_13830	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW57_13835	COG0022	dehydrogenase e1 component
EXW57_13840	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW57_13860	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_13865	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW57_13865	COG0456	acetyltransferase
EXW57_13900	COG4176	ABC-type proline glycine betaine transport system permease component
EXW57_13905	COG0517	IMP dehydrogenase activity
EXW57_13905	COG4175	Glycine betaine
EXW57_13930	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW57_13935	COG2153	protein acetylation
EXW57_13940	COG3397	chitin binding
EXW57_13950	COG1819	glycosyl
EXW57_13965	COG2205	protein histidine kinase activity
EXW57_13970	COG2315	Protein conserved in bacteria
EXW57_14025	COG3973	AAA domain
EXW57_14035	COG2105	PFAM AIG2 family protein
EXW57_14040	COG0514	ATP-dependent DNA helicase (RecQ)
EXW57_14060	COG4637	Psort location Cytoplasmic, score
EXW57_14070	COG1227	inorganic diphosphatase activity
EXW57_14075	COG3397	chitin binding
EXW57_14080	COG2318	DinB family
EXW57_14100	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW57_14105	COG1115	amino acid carrier protein
EXW57_14110	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_14115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW57_14125	COG3938	Belongs to the proline racemase family
EXW57_14130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW57_14170	COG0586	Pfam SNARE associated Golgi protein
EXW57_14185	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW57_14190	COG4166	transmembrane transport
EXW57_14200	COG4948	Mandelate Racemase Muconate Lactonizing
EXW57_14220	COG0667	Aldo Keto reductase
EXW57_14260	COG2936	dipeptidyl-peptidase activity
EXW57_14270	COG0745	RESPONSE REGULATOR receiver
EXW57_14290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW57_14295	COG1164	Oligoendopeptidase f
EXW57_14310	COG1307	EDD domain protein, DegV family
EXW57_14340	COG1335	isochorismatase
EXW57_14355	COG2814	Major facilitator Superfamily
EXW57_14365	COG1664	Polymer-forming cytoskeletal
EXW57_14370	COG0789	Transcriptional regulator
EXW57_14375	COG4533	DNA binding
EXW57_14380	COG0477	Major facilitator Superfamily
EXW57_14380	COG2814	Major facilitator Superfamily
EXW57_14400	COG2261	transglycosylase associated protein
EXW57_14415	COG2226	methyltransferase
EXW57_14450	COG0436	Aminotransferase
EXW57_14455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW57_14480	COG1131	(ABC) transporter
EXW57_14485	COG2188	Transcriptional regulator
EXW57_14525	COG0628	permease
EXW57_14570	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW57_14580	COG0697	spore germination
EXW57_14585	COG2318	DinB family
EXW57_14630	COG2814	Major facilitator Superfamily
EXW57_14635	COG1368	sulfuric ester hydrolase activity
EXW57_14650	COG0488	(ABC) transporter
EXW57_14740	COG1033	growth of symbiont in host cell
EXW57_14740	COG2409	Drug exporters of the RND superfamily
EXW57_14750	COG1309	transcriptional regulator
EXW57_14770	COG0287	Prephenate dehydrogenase
EXW57_14785	COG1605	Chorismate mutase
EXW57_14785	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW57_14825	COG3584	3D domain protein
EXW57_14825	COG1388	LysM domain
EXW57_14835	COG0346	lactoylglutathione lyase activity
EXW57_14845	COG0431	NADPH-dependent FMN reductase
EXW57_14875	COG0579	oxidoreductase
EXW57_14880	COG1879	ABC-type sugar transport system periplasmic component
EXW57_14890	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW57_14895	COG1129	ABC transporter
EXW57_14900	COG2390	Transcriptional regulator
EXW57_14920	COG2226	methyltransferase
EXW57_14940	COG2329	Antibiotic biosynthesis monooxygenase
EXW57_14965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_14970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW57_14975	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW57_14980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW57_14985	COG3239	Fatty acid desaturase
EXW57_15005	COG3842	ATPase activity
EXW57_15030	COG1175	transmembrane transport
EXW57_15035	COG1349	DNA-binding transcription factor activity
EXW57_15045	COG3655	Transcriptional regulator
EXW57_15060	COG4377	Putative membrane peptidase family (DUF2324)
EXW57_15080	COG3279	Response regulator of the LytR AlgR family
EXW57_15095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_15100	COG0346	lactoylglutathione lyase activity
EXW57_15135	COG0714	Associated with various cellular activities
EXW57_15155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW57_15160	COG0753	catalase activity
EXW57_15170	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW57_15190	COG0778	Nitroreductase
EXW57_15195	COG1846	Transcriptional regulator
EXW57_15235	COG1725	Transcriptional regulator
EXW57_15265	COG2207	Transcriptional regulator
EXW57_15270	COG0456	acetyltransferase
EXW57_15285	COG0697	spore germination
EXW57_15290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_15330	COG0814	amino acid
EXW57_15335	COG0697	spore germination
EXW57_15345	COG0642	Histidine kinase
EXW57_15350	COG0745	RESPONSE REGULATOR receiver
EXW57_15355	COG0596	Alpha beta hydrolase
EXW57_15365	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW57_15365	COG0456	acetyltransferase
EXW57_15390	COG0730	response to heat
EXW57_15400	COG0833	amino acid
EXW57_15410	COG4335	DNA alkylation repair
EXW57_15440	COG0681	Belongs to the peptidase S26 family
EXW57_15445	COG0768	penicillin binding
EXW57_15460	COG3104	oligopeptide transport
EXW57_15465	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW57_15480	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW57_15485	COG1984	allophanate hydrolase subunit 2
EXW57_15490	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW57_15495	COG1414	Transcriptional regulator
EXW57_15515	COG1960	acyl-CoA dehydrogenase activity
EXW57_15540	COG0640	Transcriptional regulator
EXW57_15550	COG3314	Sporulation integral membrane protein YlbJ
EXW57_15570	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW57_15575	COG0577	efflux transmembrane transporter activity
EXW57_15580	COG0577	efflux transmembrane transporter activity
EXW57_15585	COG1136	(ABC) transporter
EXW57_15620	COG3848	Pyruvate phosphate dikinase
EXW57_15620	COG0574	Belongs to the PEP-utilizing enzyme family
EXW57_15630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW57_15655	COG5002	protein histidine kinase activity
EXW57_15660	COG0745	RESPONSE REGULATOR receiver
EXW57_15670	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW57_15700	COG0798	PFAM Bile acid sodium symporter
EXW57_15705	COG0346	lactoylglutathione lyase activity
EXW57_15710	COG0640	Transcriptional regulator
EXW57_15725	COG2211	Major facilitator Superfamily
EXW57_15740	COG1309	transcriptional regulator
EXW57_15750	COG1522	sequence-specific DNA binding
EXW57_15770	COG0346	lactoylglutathione lyase activity
EXW57_15800	COG0745	RESPONSE REGULATOR receiver
EXW57_15805	COG5002	protein histidine kinase activity
EXW57_15805	COG3850	Histidine kinase
EXW57_15835	COG1073	alpha beta
EXW57_15845	COG0814	amino acid
EXW57_15850	COG1760	l-serine dehydratase
EXW57_15855	COG1760	l-serine dehydratase
EXW57_15865	COG5002	protein histidine kinase activity
EXW57_15870	COG0745	RESPONSE REGULATOR receiver
EXW57_15880	COG5002	protein histidine kinase activity
EXW57_15905	COG4977	sequence-specific DNA binding
EXW57_15945	COG2814	Major facilitator Superfamily
EXW57_15960	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW57_15980	COG1476	TRANSCRIPTIONal
EXW57_15990	COG2226	methyltransferase
EXW57_16005	COG1696	Membrane protein involved in D-alanine export
EXW57_16015	COG1690	Belongs to the RtcB family
EXW57_16030	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW57_16045	COG1136	(ABC) transporter
EXW57_16050	COG0577	efflux transmembrane transporter activity
EXW57_16070	COG3850	Histidine kinase
EXW57_16070	COG5002	protein histidine kinase activity
EXW57_16080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_16095	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW57_16115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW57_16160	COG2814	Major facilitator Superfamily
EXW57_16245	COG0477	Major facilitator Superfamily
EXW57_16260	COG1846	Transcriptional regulator
EXW57_16265	COG2814	Major facilitator Superfamily
EXW57_16305	COG0640	Transcriptional regulator
EXW57_16335	COG1329	Transcriptional regulator
EXW57_16390	COG5002	protein histidine kinase activity
EXW57_16405	COG1136	(ABC) transporter
EXW57_16420	COG1131	(ABC) transporter
EXW57_16495	COG0789	Transcriptional regulator
EXW57_16555	COG4187	Peptidase family M20/M25/M40
EXW57_16560	COG1414	Transcriptional regulator
EXW57_16570	COG0833	amino acid
EXW57_16580	COG2031	fatty acid transporter
EXW57_16590	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW57_16640	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW57_16645	COG1288	antiporter activity
EXW57_16650	COG2356	endonuclease I
EXW57_16655	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW57_16660	COG3620	sequence-specific DNA binding
EXW57_16680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW57_16700	COG1785	Belongs to the alkaline phosphatase family
EXW57_16705	COG0778	Nitroreductase
EXW57_16710	COG1733	regulation of RNA biosynthetic process
EXW57_16730	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_16740	COG1131	(ABC) transporter
EXW57_16770	COG1011	Hydrolase
EXW57_16775	COG2365	Tyrosine phosphatase family
EXW57_16800	COG0346	lactoylglutathione lyase activity
EXW57_16805	COG1940	carbohydrate kinase activity
EXW57_16810	COG0738	Major facilitator superfamily
EXW57_16815	COG0110	maltose O-acetyltransferase activity
EXW57_16830	COG0628	permease
EXW57_16835	COG2261	transglycosylase associated protein
EXW57_16865	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW57_16875	COG1253	flavin adenine dinucleotide binding
EXW57_16880	COG0789	Transcriptional regulator
EXW57_16890	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW57_16915	COG0697	spore germination
EXW57_16920	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW57_16925	COG3813	Protein conserved in bacteria
EXW57_16930	COG2706	6-phosphogluconolactonase activity
EXW57_16935	COG1070	Carbohydrate kinase
EXW57_16945	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW57_16950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW57_16965	COG0814	amino acid
EXW57_16985	COG1393	Belongs to the ArsC family
EXW57_16995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_17010	COG0494	nUDIX hydrolase
EXW57_17025	COG0384	phenazine biosynthesis protein PhzF
EXW57_17035	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_17040	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW57_17045	COG1733	regulation of RNA biosynthetic process
EXW57_17060	COG1191	sigma factor activity
EXW57_17075	COG1876	peptidase activity
EXW57_17115	COG0741	lytic transglycosylase activity
EXW57_17140	COG5002	protein histidine kinase activity
EXW57_17190	COG0814	amino acid
EXW57_17215	COG1151	hydroxylamine reductase activity
EXW57_17240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_17250	COG2072	flavoprotein involved in K transport
EXW57_17295	COG1695	Transcriptional regulator
EXW57_17300	COG0604	alcohol dehydrogenase
EXW57_17305	COG1113	amino acid transport
EXW57_17315	COG2814	Major facilitator Superfamily
EXW57_17325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW57_17330	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_17340	COG0534	Mate efflux family protein
EXW57_17345	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_17350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW57_17365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW57_17370	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW57_17390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_17395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_17400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_17405	COG3739	integral membrane protein
EXW57_17425	COG0583	DNA-binding transcription factor activity
EXW57_17450	COG1193	negative regulation of DNA recombination
EXW57_17470	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW57_17475	COG1164	Oligoendopeptidase f
EXW57_17480	COG2957	Belongs to the agmatine deiminase family
EXW57_17500	COG3781	membrane
EXW57_17515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_17550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW57_17555	COG0640	Transcriptional regulator
EXW57_17560	COG0604	alcohol dehydrogenase
EXW57_17565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW57_17570	COG0457	Tetratricopeptide repeat
EXW57_17585	COG2808	Putative FMN-binding domain
EXW57_17590	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW57_17600	COG0277	FAD linked oxidase domain protein
EXW57_17620	COG1285	pathogenesis
EXW57_17630	COG2514	catechol 2,3-dioxygenase activity
EXW57_17635	COG2720	vancomycin resistance protein
EXW57_17660	COG1278	Cold shock
EXW57_17670	COG0716	FMN binding
EXW57_17680	COG0494	nUDIX hydrolase
EXW57_17700	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_17710	COG0165	Argininosuccinate lyase
EXW57_17725	COG4145	pantothenate transmembrane transporter activity
EXW57_17735	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_17740	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_17750	COG1657	PFAM Prenyltransferase squalene oxidase
EXW57_17755	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW57_17760	COG2962	Rard protein
EXW57_17765	COG3326	Membrane
EXW57_17770	COG0531	amino acid
EXW57_17805	COG2226	methyltransferase
EXW57_17810	COG4166	transmembrane transport
EXW57_17815	COG4166	transmembrane transport
EXW57_17820	COG4166	transmembrane transport
EXW57_17825	COG1316	TRANSCRIPTIONal
EXW57_17835	COG1595	DNA-templated transcription, initiation
EXW57_17845	COG1131	(ABC) transporter
EXW57_17865	COG0673	inositol 2-dehydrogenase activity
EXW57_17870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW57_17875	COG0187	DNA topoisomerase II activity
EXW57_17880	COG1832	CoA-binding protein
EXW57_17885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW57_17890	COG0745	RESPONSE REGULATOR receiver
EXW57_17900	COG1328	CTP reductase activity
EXW57_17910	COG4841	protein insertion into membrane
EXW57_17915	COG0824	Thioesterase
EXW57_17940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW57_17960	COG1132	(ABC) transporter
EXW57_17965	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW57_17995	COG2211	Major facilitator Superfamily
EXW57_18005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW57_18020	COG0183	Belongs to the thiolase family
EXW57_18025	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_18030	COG1268	BioY protein
EXW57_18035	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_18040	COG1396	sequence-specific DNA binding
EXW57_18065	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EXW57_18085	COG0830	nickel cation binding
EXW57_18125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_18140	COG5002	protein histidine kinase activity
EXW57_18150	COG0400	carboxylic ester hydrolase activity
EXW57_18155	COG0346	lactoylglutathione lyase activity
EXW57_18160	COG0069	glutamate synthase activity
EXW57_18165	COG1902	pentaerythritol trinitrate reductase activity
EXW57_18175	COG1329	Transcriptional regulator
EXW57_18180	COG0010	Belongs to the arginase family
EXW57_18190	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW57_18195	COG2986	histidine ammonia-lyase
EXW57_18205	COG2226	methyltransferase
EXW57_18235	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW57_18240	COG0785	Cytochrome C biogenesis protein
EXW57_18255	COG1473	amidohydrolase
EXW57_18260	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW57_18265	COG1131	(ABC) transporter
EXW57_18275	COG0583	DNA-binding transcription factor activity
EXW57_18285	COG1346	cytolysis
EXW57_18300	COG0730	response to heat
EXW57_18310	COG3409	Peptidoglycan-binding domain 1 protein
EXW57_18310	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW57_18330	COG1132	(ABC) transporter
EXW57_18335	COG1132	(ABC) transporter
EXW57_18340	COG3763	UPF0154 protein
EXW57_18360	COG3639	organic phosphonate transmembrane transporter activity
EXW57_18370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW57_18375	COG0737	Belongs to the 5'-nucleotidase family
EXW57_18385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW57_18390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW57_18405	COG1695	Transcriptional regulator
EXW57_18410	COG1132	(ABC) transporter
EXW57_18440	COG0367	asparagine synthase
EXW57_18445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW57_18455	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW57_18460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW57_18465	COG3420	alginic acid biosynthetic process
EXW57_18465	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW57_18490	COG0438	transferase activity, transferring glycosyl groups
EXW57_18500	COG0463	Glycosyl transferase, family 2
EXW57_18500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW57_18505	COG0438	transferase activity, transferring glycosyl groups
EXW57_18510	COG0438	transferase activity, transferring glycosyl groups
EXW57_18515	COG1086	Polysaccharide biosynthesis protein
EXW57_18520	COG0489	protein tyrosine kinase activity
EXW57_18525	COG3944	biosynthesis protein
EXW57_18530	COG0174	glutamine synthetase
EXW57_18535	COG0789	Transcriptional regulator
EXW57_18540	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW57_18545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW57_18550	COG2860	membrane
EXW57_18555	COG0464	growth
EXW57_18575	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW57_18585	COG1388	LysM domain
EXW57_18585	COG3584	3D domain protein
EXW57_18590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW57_18590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW57_18590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW57_18595	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW57_18600	COG1349	DNA-binding transcription factor activity
EXW57_18605	COG1979	alcohol dehydrogenase
EXW57_18610	COG2322	membrane
EXW57_18620	COG1113	amino acid transport
EXW57_18635	COG1473	amidohydrolase
EXW57_18640	COG1408	metallophosphoesterase
EXW57_18645	COG2116	formate transmembrane transporter activity
EXW57_18660	COG2217	Heavy metal translocating P-type atpase
EXW57_18665	COG2608	mercury ion transmembrane transporter activity
EXW57_18670	COG1937	Protein conserved in bacteria
EXW57_18700	COG4566	intracellular signal transduction
EXW57_18710	COG2819	hydrolase of the alpha beta superfamily
EXW57_18715	COG1120	ATPase activity
EXW57_18720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_18725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_18730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_18735	COG0708	Exodeoxyribonuclease III
EXW57_18740	COG2169	Transcriptional regulator
EXW57_18745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW57_18750	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW57_18755	COG2706	6-phosphogluconolactonase activity
EXW57_18760	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW57_18765	COG2364	Membrane
EXW57_18775	COG0346	lactoylglutathione lyase activity
EXW57_18780	COG3300	MHYT domain
EXW57_18780	COG5001	Diguanylate cyclase
EXW57_18820	COG1346	cytolysis
EXW57_18830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_18835	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW57_18835	COG0596	Alpha beta hydrolase
EXW57_18840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW57_18855	COG2188	Transcriptional regulator
EXW57_18860	COG2723	6-phospho-beta-galactosidase activity
EXW57_18865	COG0823	Involved in the tonB-independent uptake of proteins
EXW57_18870	COG3773	Cell wall hydrolase
EXW57_18880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW57_18890	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW57_18895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW57_18900	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW57_18910	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW57_18915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW57_18920	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW57_18925	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW57_18925	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW57_18935	COG2359	stage V sporulation protein S
EXW57_18940	COG1692	metallophosphoesterase
EXW57_18945	COG1418	mRNA catabolic process
EXW57_18950	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW57_18955	COG1546	Belongs to the CinA family
EXW57_18955	COG1058	Belongs to the CinA family
EXW57_18960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW57_18965	COG1426	Protein conserved in bacteria
EXW57_18980	COG0300	oxidoreductase activity
EXW57_18985	COG0612	Peptidase, M16
EXW57_18990	COG0612	Peptidase, M16
EXW57_18995	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW57_19000	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW57_19005	COG3845	ABC transporter
EXW57_19010	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW57_19015	COG2188	Transcriptional regulator
EXW57_19025	COG1674	ftsk spoiiie
EXW57_19035	COG0740	serine-type endopeptidase activity
EXW57_19040	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW57_19050	COG0527	aspartate kinase activity
EXW57_19055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW57_19060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW57_19065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW57_19070	COG1873	PFAM PRC-barrel domain
EXW57_19075	COG0612	Peptidase, M16
EXW57_19080	COG0726	polysaccharide deacetylase
EXW57_19085	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW57_19095	COG0196	riboflavin kinase activity
EXW57_19105	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW57_19110	COG1550	Protein conserved in bacteria
EXW57_19115	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW57_19120	COG1358	cellular component organization or biogenesis
EXW57_19125	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW57_19130	COG0195	Participates in both transcription termination and antitermination
EXW57_19135	COG0779	Required for maturation of 30S ribosomal subunits
EXW57_19145	COG0442	prolyl-tRNA aminoacylation
EXW57_19150	COG0750	zinc metalloprotease
EXW57_19160	COG4589	Belongs to the CDS family
EXW57_19170	COG0233	cytoplasmic translational termination
EXW57_19175	COG0528	UMP kinase activity
EXW57_19180	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW57_19190	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW57_19195	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW57_19200	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW57_19205	COG4974	Belongs to the 'phage' integrase family
EXW57_19210	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW57_19215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW57_19220	COG0758	DNA mediated transformation
EXW57_19225	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW57_19230	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW57_19235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW57_19250	COG0335	large ribosomal subunit rRNA binding
EXW57_19255	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW57_19260	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW57_19265	COG1837	Belongs to the UPF0109 family
EXW57_19275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW57_19285	COG0552	protein localization to endoplasmic reticulum
EXW57_19290	COG1196	nuclear chromosome segregation
EXW57_19295	COG0571	ribonuclease III activity
EXW57_19300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW57_19305	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_19310	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW57_19315	COG0416	fatty acid biosynthetic process
EXW57_19320	COG1349	DNA-binding transcription factor activity
EXW57_19320	COG2050	protein possibly involved in aromatic compounds catabolism
EXW57_19325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW57_19330	COG1461	Dihydroxyacetone kinase
EXW57_19335	COG1302	Protein conserved in bacteria
EXW57_19350	COG1564	THIamine pyrophosphokinase
EXW57_19355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW57_19365	COG0515	serine threonine protein kinase
EXW57_19365	COG2815	serine threonine protein kinase
EXW57_19370	COG0631	protein serine/threonine phosphatase activity
EXW57_19375	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW57_19380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW57_19380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW57_19385	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW57_19390	COG0242	peptide deformylase activity
EXW57_19395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW57_19400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW57_19405	COG1758	RNA polymerase activity
EXW57_19420	COG1561	YicC-like family, N-terminal region
EXW57_19425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW57_19435	COG0006	proline dipeptidase activity
EXW57_19455	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW57_19465	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EXW57_19475	COG0167	dihydroorotate dehydrogenase activity
EXW57_19480	COG0543	2 iron, 2 sulfur cluster binding
EXW57_19485	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW57_19495	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW57_19500	COG0540	Belongs to the ATCase OTCase family
EXW57_19510	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW57_19515	COG0564	pseudouridine synthase activity
EXW57_19520	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW57_19530	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW57_19535	COG3599	regulation of cell shape
EXW57_19540	COG2302	S4 RNA-binding domain
EXW57_19545	COG0762	integral membrane protein
EXW57_19550	COG1799	cell septum assembly
EXW57_19555	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW57_19565	COG1873	PFAM PRC-barrel domain
EXW57_19570	COG1191	sigma factor activity
EXW57_19575	COG1191	sigma factor activity
EXW57_19585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW57_19590	COG0849	cell division
EXW57_19595	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW57_19610	COG0772	Belongs to the SEDS family
EXW57_19615	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW57_19620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW57_19625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW57_19630	COG0768	penicillin binding
EXW57_19635	COG0768	penicillin binding
EXW57_19645	COG0275	rRNA processing
EXW57_19650	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW57_19655	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW57_19660	COG0454	-acetyltransferase
EXW57_19670	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW57_19675	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW57_19680	COG1323	Belongs to the UPF0348 family
EXW57_19685	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW57_19690	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW57_19695	COG3314	Sporulation integral membrane protein YlbJ
EXW57_19705	COG0742	ribosomal rna small subunit methyltransferase
EXW57_19715	COG4471	UPF0298 protein
EXW57_19720	COG3679	Belongs to the UPF0342 family
EXW57_19725	COG0406	alpha-ribazole phosphatase activity
EXW57_19740	COG2340	Cysteine-rich secretory protein family
EXW57_19750	COG3336	cytochrome c oxidase
EXW57_19775	COG0109	protoheme IX farnesyltransferase activity
EXW57_19780	COG1612	heme a metabolic process
EXW57_19785	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW57_19795	COG0772	Belongs to the SEDS family
EXW57_19800	COG4838	Belongs to the UPF0358 family
EXW57_19805	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW57_19810	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW57_19820	COG4896	Protein conserved in bacteria
EXW57_19835	COG1217	gtp-binding protein TYPA
EXW57_19845	COG0483	inositol monophosphate 1-phosphatase activity
EXW57_19855	COG4493	Belongs to the UPF0637 family
EXW57_19860	COG4476	Belongs to the UPF0223 family
EXW57_19865	COG1982	Orn Lys Arg decarboxylase major
EXW57_19910	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW57_19915	COG0022	dehydrogenase e1 component
EXW57_19920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW57_19935	COG0561	phosphatase activity
EXW57_19945	COG5503	Protein of unknown function (DUF1447)
EXW57_19950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW57_19955	COG0569	domain protein
EXW57_19965	COG1473	amidohydrolase
EXW57_19970	COG2171	N-acyltransferase activity
EXW57_19975	COG0583	DNA-binding transcription factor activity
EXW57_19980	COG0517	IMP dehydrogenase activity
EXW57_19990	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW57_20000	COG4703	Protein of unknown function (DUF1797)
EXW57_20015	COG2200	EAL domain
EXW57_20020	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_20025	COG1408	metallophosphoesterase
EXW57_20070	COG2814	Major facilitator Superfamily
EXW57_20080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW57_20090	COG3209	COG3209 Rhs family protein
EXW57_20100	COG2205	protein histidine kinase activity
EXW57_20110	COG0436	Aminotransferase
EXW57_20115	COG1609	Transcriptional regulator
EXW57_20120	COG3833	ABC-type maltose transport systems, permease component
EXW57_20125	COG1175	transmembrane transport
EXW57_20130	COG2182	Extracellular solute-binding protein
EXW57_20140	COG0366	Alpha amylase catalytic
EXW57_20145	COG3842	ATPase activity
EXW57_20190	COG0183	Belongs to the thiolase family
EXW57_20225	COG1695	Transcriptional regulator
EXW57_20230	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_20240	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW57_20245	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW57_20250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW57_20255	COG0436	Aminotransferase
EXW57_20260	COG1850	ribulose-bisphosphate carboxylase activity
EXW57_20265	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW57_20270	COG0235	Class ii aldolase
EXW57_20275	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW57_20290	COG2084	Dehydrogenase
EXW57_20300	COG2199	diguanylate cyclase activity
EXW57_20305	COG0778	Nitroreductase
EXW57_20330	COG1263	PTS System
EXW57_20330	COG2190	(PTS) system
EXW57_20330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_20335	COG3711	transcriptional antiterminator
EXW57_20345	COG2188	Transcriptional regulator
EXW57_20350	COG0363	glucosamine-6-phosphate deaminase activity
EXW57_20355	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW57_20365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW57_20375	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW57_20385	COG1547	Domain of unknown function (DUF309)
EXW57_20395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW57_20400	COG4086	secreted protein
EXW57_20405	COG0561	phosphatase activity
EXW57_20410	COG0697	spore germination
EXW57_20425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW57_20465	COG1686	Belongs to the peptidase S11 family
EXW57_20470	COG1725	Transcriptional regulator
EXW57_20475	COG1131	(ABC) transporter
EXW57_20500	COG1846	Transcriptional regulator
EXW57_20515	COG0598	Magnesium transport protein CorA
EXW57_20530	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW57_20540	COG4974	Belongs to the 'phage' integrase family
EXW57_20550	COG0735	belongs to the Fur family
EXW57_20555	COG1300	Membrane
EXW57_20575	COG0667	Aldo Keto reductase
EXW57_20580	COG0656	L-ascorbic acid biosynthetic process
EXW57_20585	COG0456	acetyltransferase
EXW57_20585	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW57_20595	COG0737	Belongs to the 5'-nucleotidase family
EXW57_20595	COG1525	nuclease
EXW57_20595	COG4085	toxin activity
EXW57_20600	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW57_20610	COG0596	Alpha beta hydrolase
EXW57_20615	COG2056	Na+-H+ antiporter family
EXW57_20620	COG1609	Transcriptional regulator
EXW57_20625	COG0456	acetyltransferase
EXW57_20630	COG1073	alpha beta
EXW57_20645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW57_20645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW57_20650	COG0307	riboflavin synthase, alpha
EXW57_20655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW57_20655	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW57_20670	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW57_20675	COG4106	trans-aconitate 2-methyltransferase activity
EXW57_20680	COG2226	methyltransferase
EXW57_20680	COG1073	alpha beta
EXW57_20685	COG0156	8-amino-7-oxononanoate synthase activity
EXW57_20695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW57_20705	COG1757	Na H antiporter
EXW57_20710	COG0737	Belongs to the 5'-nucleotidase family
EXW57_20720	COG1522	sequence-specific DNA binding
EXW57_20755	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW57_20765	COG0300	oxidoreductase activity
EXW57_20770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_20775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW57_20780	COG1760	l-serine dehydratase
EXW57_20785	COG1760	l-serine dehydratase
EXW57_20795	COG1234	tRNA 3'-trailer cleavage
EXW57_20820	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW57_20825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_20835	COG1376	ErfK ybiS ycfS ynhG family protein
EXW57_20840	COG4129	membrane
EXW57_20845	COG1126	abc transporter atp-binding protein
EXW57_20850	COG0765	amino acid transport
EXW57_20855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW57_20870	COG2816	NAD+ diphosphatase activity
EXW57_20875	COG2323	membrane
EXW57_20880	COG0772	Belongs to the SEDS family
EXW57_20890	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW57_20895	COG0022	dehydrogenase e1 component
EXW57_20900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW57_20905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW57_20910	COG3426	butyrate kinase activity
EXW57_20920	COG0280	phosphate acetyltransferase
EXW57_20930	COG3290	protein histidine kinase activity
EXW57_20930	COG3829	transcription factor binding
EXW57_20940	COG0584	glycerophosphoryl diester phosphodiesterase
EXW57_20945	COG3093	addiction module antidote protein HigA
EXW57_20955	COG0745	RESPONSE REGULATOR receiver
EXW57_20965	COG0750	zinc metalloprotease
EXW57_20970	COG0497	DNA recombination
EXW57_20975	COG1438	arginine binding
EXW57_20980	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW57_20985	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW57_20990	COG0142	geranyltranstransferase activity
EXW57_20995	COG1722	exodeoxyribonuclease VII activity
EXW57_21000	COG1570	exodeoxyribonuclease VII activity
EXW57_21005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW57_21010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW57_21015	COG1302	Protein conserved in bacteria
EXW57_21020	COG0439	Biotin carboxylase
EXW57_21025	COG0511	ligase activity, forming carbon-carbon bonds
EXW57_21070	COG3854	ATPases associated with a variety of cellular activities
EXW57_21090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW57_21095	COG0006	proline dipeptidase activity
EXW57_21100	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW57_21110	COG3872	metal-dependent enzyme
EXW57_21120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW57_21155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW57_21165	COG1609	Transcriptional regulator
EXW57_21175	COG2076	Multidrug Resistance protein
EXW57_21180	COG2076	Multidrug Resistance protein
EXW57_21215	COG1725	Transcriptional regulator
EXW57_21230	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW57_21235	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW57_21240	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW57_21245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW57_21275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW57_21300	COG4970	Tfp pilus assembly protein FimT
EXW57_21310	COG1459	type II secretion system
EXW57_21315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW57_21370	COG0646	methionine synthase
EXW57_21370	COG1410	methionine synthase
EXW57_21375	COG0646	methionine synthase
EXW57_21375	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW57_21380	COG0626	cystathionine gamma-synthase activity
EXW57_21385	COG0626	cystathionine gamma-synthase activity
EXW57_21405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_21415	COG1940	carbohydrate kinase activity
EXW57_21420	COG4483	Protein conserved in bacteria
EXW57_21425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW57_21430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW57_21435	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW57_21440	COG0704	Plays a role in the regulation of phosphate uptake
EXW57_21450	COG0581	inorganic phosphate transmembrane transporter activity
EXW57_21455	COG0573	inorganic phosphate transmembrane transporter activity
EXW57_21460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW57_21465	COG0768	penicillin binding
EXW57_21470	COG0477	Major facilitator Superfamily
EXW57_21475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW57_21495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW57_21500	COG0735	belongs to the Fur family
EXW57_21505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW57_21510	COG1121	(ABC) transporter
EXW57_21515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_21525	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW57_21540	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW57_21545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW57_21550	COG2384	SAM-dependent methyltransferase
EXW57_21555	COG2010	Cytochrome c
EXW57_21560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW57_21565	COG0358	DNA primase activity
EXW57_21575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW57_21580	COG0517	IMP dehydrogenase activity
EXW57_21585	COG1381	Involved in DNA repair and RecF pathway recombination
EXW57_21595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW57_21600	COG0295	cytidine deaminase activity
EXW57_21605	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW57_21610	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW57_21615	COG1480	7TM receptor with intracellular HD hydrolase
EXW57_21620	COG1702	phosphate starvation-inducible protein PhoH
EXW57_21635	COG1610	YqeY-like protein
EXW57_21640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW57_21645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW57_21650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW57_21660	COG0484	heat shock protein binding
EXW57_21665	COG0443	Heat shock 70 kDa protein
EXW57_21675	COG1420	regulation of RNA biosynthetic process
EXW57_21680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW57_21685	COG1733	regulation of RNA biosynthetic process
EXW57_21690	COG0481	GTPase activity
EXW57_21700	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW57_21705	COG0268	Binds directly to 16S ribosomal RNA
EXW57_21710	COG1466	dna polymerase III delta subunit
EXW57_21720	COG0658	competence protein
EXW57_21720	COG2333	competence protein COMEC
EXW57_21725	COG2131	deaminase
EXW57_21730	COG1555	photosystem II stabilization
EXW57_21730	COG1596	polysaccharide export
EXW57_21735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW57_21740	COG2226	methyltransferase
EXW57_21745	COG0799	negative regulation of ribosome biogenesis
EXW57_21750	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW57_21755	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW57_21760	COG1534	Rna-binding protein
EXW57_21765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW57_21770	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW57_21775	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW57_21785	COG0688	phosphatidylethanolamine metabolic process
EXW57_21795	COG1595	DNA-templated transcription, initiation
EXW57_21800	COG2357	RelA SpoT domain protein
EXW57_21810	COG1785	Belongs to the alkaline phosphatase family
EXW57_21820	COG2267	carboxylic ester hydrolase activity
EXW57_21855	COG1404	Belongs to the peptidase S8 family
EXW57_21860	COG3186	Phenylalanine-4-hydroxylase
EXW57_21865	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW57_21870	COG2514	catechol 2,3-dioxygenase activity
EXW57_21875	COG2259	Doxx family
EXW57_21915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_21925	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_21925	COG1454	alcohol dehydrogenase
EXW57_21930	COG0626	cystathionine gamma-synthase activity
EXW57_21935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW57_21940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW57_21945	COG2226	methyltransferase
EXW57_21960	COG0768	penicillin binding
EXW57_21965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW57_21970	COG0572	uridine kinase
EXW57_21975	COG0826	peptidase U32
EXW57_21980	COG0826	peptidase U32
EXW57_21985	COG4122	O-methyltransferase activity
EXW57_21990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW57_22000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW57_22005	COG4472	Bacterial protein of unknown function (DUF965)
EXW57_22010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW57_22020	COG0628	permease
EXW57_22040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW57_22050	COG0482	sulfurtransferase activity
EXW57_22055	COG1104	cysteine desulfurase activity
EXW57_22060	COG1959	2 iron, 2 sulfur cluster binding
EXW57_22065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW57_22075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW57_22080	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW57_22090	COG1490	D-aminoacyl-tRNA deacylase activity
EXW57_22095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW57_22100	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW57_22105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW57_22105	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW57_22110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW57_22115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW57_22115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW57_22125	COG2244	polysaccharide biosynthetic process
EXW57_22130	COG2323	membrane
EXW57_22140	COG1862	Preprotein translocase
EXW57_22145	COG0343	queuine tRNA-ribosyltransferase activity
EXW57_22150	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW57_22160	COG2255	four-way junction helicase activity
EXW57_22165	COG0632	four-way junction helicase activity
EXW57_22170	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW57_22195	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW57_22200	COG0157	Belongs to the NadC ModD family
EXW57_22205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW57_22210	COG1104	cysteine desulfurase activity
EXW57_22215	COG1827	regulation of RNA biosynthetic process
EXW57_22220	COG2258	MOSC domain
EXW57_22225	COG0077	Prephenate dehydratase
EXW57_22230	COG0577	efflux transmembrane transporter activity
EXW57_22235	COG0577	efflux transmembrane transporter activity
EXW57_22240	COG1136	(ABC) transporter
EXW57_22245	COG5002	protein histidine kinase activity
EXW57_22250	COG0745	RESPONSE REGULATOR receiver
EXW57_22255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW57_22260	COG3290	protein histidine kinase activity
EXW57_22270	COG2868	ribosomal protein
EXW57_22280	COG1530	ribonuclease E activity
EXW57_22285	COG1994	Peptidase M50
EXW57_22290	COG0739	heme binding
EXW57_22295	COG2894	cell division
EXW57_22300	COG0850	regulation of cytokinetic process
EXW57_22315	COG1077	Cell shape determining protein MreB Mrl
EXW57_22320	COG2003	Belongs to the UPF0758 family
EXW57_22325	COG0424	maF-like protein
EXW57_22340	COG0285	dihydrofolate synthase activity
EXW57_22355	COG1388	LysM domain
EXW57_22360	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW57_22365	COG0113	porphobilinogen synthase activity
EXW57_22370	COG1587	Uroporphyrinogen-III synthase
EXW57_22375	COG0181	hydroxymethylbilane synthase activity
EXW57_22380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW57_22385	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW57_22390	COG1846	Transcriptional regulator
EXW57_22395	COG1764	response to oxidative stress
EXW57_22400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW57_22410	COG0470	DNA polymerase III
EXW57_22410	COG1067	ATP-dependent peptidase activity
EXW57_22420	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW57_22450	COG0622	Phosphoesterase
EXW57_22460	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW57_22465	COG5401	PFAM Sporulation and spore germination
EXW57_22475	COG0477	Major facilitator Superfamily
EXW57_22480	COG2197	response regulator
EXW57_22485	COG2233	PERMEase
EXW57_22490	COG0402	S-adenosylhomocysteine deaminase activity
EXW57_22495	COG1983	PspC domain protein
EXW57_22500	COG1396	sequence-specific DNA binding
EXW57_22505	COG0697	spore germination
EXW57_22515	COG1959	2 iron, 2 sulfur cluster binding
EXW57_22520	COG1668	transmembrane transport
EXW57_22525	COG4152	abc transporter atp-binding protein
EXW57_22530	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW57_22535	COG1360	Flagellar Motor Protein
EXW57_22540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW57_22550	COG1876	peptidase activity
EXW57_22555	COG0824	Thioesterase
EXW57_22560	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW57_22565	COG1053	succinate dehydrogenase
EXW57_22570	COG2009	succinate dehydrogenase
EXW57_22575	COG1719	4-vinyl reductase, 4VR
EXW57_22580	COG0322	excinuclease ABC activity
EXW57_22585	COG3118	belongs to the thioredoxin family
EXW57_22590	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW57_22595	COG2086	electron transfer activity
EXW57_22600	COG1024	Enoyl-CoA hydratase
EXW57_22605	COG1309	transcriptional regulator
EXW57_22610	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_22630	COG2318	DinB family
EXW57_22660	COG1131	(ABC) transporter
EXW57_22665	COG2205	protein histidine kinase activity
EXW57_22670	COG0745	RESPONSE REGULATOR receiver
EXW57_22675	COG4895	conserved protein (DUF2196)
EXW57_22680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW57_22690	COG4509	Sortase family
EXW57_22695	COG1120	ATPase activity
EXW57_22710	COG5386	Cell surface protein
EXW57_22720	COG5386	Cell surface protein
EXW57_22725	COG1114	Component of the transport system for branched-chain amino acids
EXW57_22735	COG1193	negative regulation of DNA recombination
EXW57_22740	COG1796	DNA polymerase
EXW57_22740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW57_22745	COG1286	toxin biosynthetic process
EXW57_22750	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW57_22755	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW57_22780	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW57_22785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW57_22795	COG1418	mRNA catabolic process
EXW57_22825	COG2814	Major facilitator Superfamily
EXW57_22830	COG1566	PFAM secretion protein HlyD family protein
EXW57_22835	COG1309	transcriptional regulator
EXW57_22840	COG1363	Peptidase, m42
EXW57_22850	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW57_22865	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW57_22875	COG1484	DNA-dependent DNA replication
EXW57_22880	COG3611	Membrane attachment protein
EXW57_22885	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW57_22890	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW57_22895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW57_22900	COG0237	dephospho-CoA kinase activity
EXW57_22905	COG1971	Probably functions as a manganese efflux pump
EXW57_22915	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW57_22915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW57_22920	COG5002	protein histidine kinase activity
EXW57_22925	COG0745	RESPONSE REGULATOR receiver
EXW57_22940	COG0039	L-malate dehydrogenase activity
EXW57_22945	COG0538	isocitrate dehydrogenase activity
EXW57_22950	COG0372	Belongs to the citrate synthase family
EXW57_22965	COG0628	permease
EXW57_22970	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW57_22980	COG0205	6-phosphofructokinase activity
EXW57_22990	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW57_22995	COG1725	Transcriptional regulator
EXW57_23000	COG0281	malic enzyme
EXW57_23005	COG0587	DNA-directed DNA polymerase activity
EXW57_23020	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW57_23040	COG4109	DRTGG domain
EXW57_23050	COG0006	proline dipeptidase activity
EXW57_23080	COG0662	Cupin 2, conserved barrel domain protein
EXW57_23090	COG1476	TRANSCRIPTIONal
EXW57_23105	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_23110	COG0589	response to stress
EXW57_23140	COG0137	argininosuccinate synthase activity
EXW57_23155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_23175	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW57_23180	COG0827	DNA restriction-modification system
EXW57_23185	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW57_23190	COG3874	Sporulation protein YtfJ
EXW57_23205	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW57_23215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW57_23230	COG1104	cysteine desulfurase activity
EXW57_23240	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW57_23255	COG1309	transcriptional regulator
EXW57_23260	COG1956	GAF domain-containing protein
EXW57_23265	COG0626	cystathionine gamma-synthase activity
EXW57_23270	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW57_23295	COG1595	DNA-templated transcription, initiation
EXW57_23305	COG0110	maltose O-acetyltransferase activity
EXW57_23310	COG0456	acetyltransferase
EXW57_23315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW57_23320	COG0454	-acetyltransferase
EXW57_23325	COG0517	IMP dehydrogenase activity
EXW57_23330	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW57_23345	COG0745	RESPONSE REGULATOR receiver
EXW57_23350	COG5002	protein histidine kinase activity
EXW57_23355	COG0666	response to abiotic stimulus
EXW57_23365	COG1970	mechanosensitive ion channel activity
EXW57_23385	COG1609	Transcriptional regulator
EXW57_23395	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW57_23395	COG1605	Chorismate mutase
EXW57_23400	COG4851	CamS sex pheromone cAM373 precursor
EXW57_23405	COG3118	belongs to the thioredoxin family
EXW57_23415	COG2309	aminopeptidase activity
EXW57_23440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_23445	COG1695	Transcriptional regulator
EXW57_23455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW57_23465	COG1674	ftsk spoiiie
EXW57_23480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW57_23485	COG4848	Belongs to the UPF0354 family
EXW57_23490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW57_23495	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW57_23500	COG1363	Peptidase, m42
EXW57_23510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_23515	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW57_23525	COG0510	thiamine kinase activity
EXW57_23530	COG1523	belongs to the glycosyl hydrolase 13 family
EXW57_23540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW57_23545	COG1349	DNA-binding transcription factor activity
EXW57_23550	COG1187	pseudouridine synthase activity
EXW57_23555	COG2244	polysaccharide biosynthetic process
EXW57_23560	COG2081	HI0933 family
EXW57_23565	COG2814	Major facilitator Superfamily
EXW57_23575	COG3832	glyoxalase III activity
EXW57_23595	COG1329	Transcriptional regulator
EXW57_23620	COG0314	molybdopterin synthase activity
EXW57_23625	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW57_23630	COG0303	'Molybdopterin
EXW57_23635	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW57_23640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW57_23645	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW57_23670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW57_23680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW57_23720	COG0495	leucyl-tRNA aminoacylation
EXW57_23725	COG2814	Major facilitator Superfamily
EXW57_23730	COG0475	glutathione-regulated potassium exporter activity
EXW57_23735	COG0490	domain, Protein
EXW57_23740	COG0582	viral genome integration into host DNA
EXW57_23755	COG1136	(ABC) transporter
EXW57_23770	COG1242	4 iron, 4 sulfur cluster binding
EXW57_23775	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW57_23785	COG1131	(ABC) transporter
EXW57_23795	COG1794	racemase activity, acting on amino acids and derivatives
EXW57_23815	COG2267	carboxylic ester hydrolase activity
EXW57_23820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW57_23825	COG0671	phosphoesterase, PA-phosphatase related
EXW57_23830	COG0438	transferase activity, transferring glycosyl groups
EXW57_23840	COG0521	Mo-molybdopterin cofactor biosynthetic process
EXW57_23860	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW57_23865	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW57_23905	COG5002	protein histidine kinase activity
EXW57_23910	COG3852	Histidine kinase
EXW57_23915	COG0753	catalase activity
EXW57_23920	COG2267	carboxylic ester hydrolase activity
EXW57_23930	COG1368	sulfuric ester hydrolase activity
EXW57_23940	COG4895	conserved protein (DUF2196)
EXW57_23955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW57_23960	COG1116	anion transmembrane transporter activity
EXW57_23965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW57_23990	COG0494	nUDIX hydrolase
EXW57_24030	COG2076	Multidrug Resistance protein
EXW57_24035	COG2076	Multidrug Resistance protein
EXW57_24040	COG0789	Transcriptional regulator
EXW57_24045	COG1854	S-ribosylhomocysteine lyase activity
EXW57_24055	COG0288	reversible hydration of carbon dioxide
EXW57_24060	COG1271	oxidase subunit
EXW57_24065	COG1294	oxidase, subunit
EXW57_24085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_24110	COG1842	Phage shock protein A
EXW57_24135	COG3859	Proton-coupled thiamine transporter YuaJ
EXW57_24140	COG5002	protein histidine kinase activity
EXW57_24145	COG0745	RESPONSE REGULATOR receiver
EXW57_24170	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW57_24175	COG1597	lipid kinase activity
EXW57_24210	COG1136	(ABC) transporter
EXW57_24240	COG5002	protein histidine kinase activity
EXW57_24250	COG0586	Pfam SNARE associated Golgi protein
EXW57_24265	COG0577	efflux transmembrane transporter activity
EXW57_24270	COG1136	(ABC) transporter
EXW57_24275	COG2207	Transcriptional regulator
EXW57_24275	COG3708	Transcriptional regulator
EXW57_24285	COG1131	(ABC) transporter
EXW57_24295	COG5658	integral membrane protein
EXW57_24300	COG0640	Transcriptional regulator
EXW57_24305	COG0745	RESPONSE REGULATOR receiver
EXW57_24310	COG2205	protein histidine kinase activity
EXW57_24315	COG0577	efflux transmembrane transporter activity
EXW57_24320	COG0577	efflux transmembrane transporter activity
EXW57_24325	COG1136	(ABC) transporter
EXW57_24330	COG0577	efflux transmembrane transporter activity
EXW57_24345	COG2188	Transcriptional regulator
EXW57_24365	COG3964	amidohydrolase
EXW57_24385	COG4948	Mandelate Racemase Muconate Lactonizing
EXW57_24390	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_24395	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW57_24405	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW57_24410	COG1169	isochorismate synthase
EXW57_24415	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW57_24420	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW57_24425	COG1278	Cold shock
EXW57_24435	COG0789	Transcriptional regulator
EXW57_24445	COG0058	SHG alpha-glucan phosphorylase activity
EXW57_24455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW57_24460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW57_24465	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW57_24500	COG1595	DNA-templated transcription, initiation
EXW57_24635	COG1285	pathogenesis
EXW57_24640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW57_24650	COG0166	Belongs to the GPI family
EXW57_24660	COG2155	Conserved Protein
EXW57_24665	COG1098	S1 RNA binding domain
EXW57_24670	COG0436	Aminotransferase
EXW57_24675	COG1522	sequence-specific DNA binding
EXW57_24680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW57_24690	COG2267	carboxylic ester hydrolase activity
EXW57_24700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW57_24715	COG5018	Exonuclease
EXW57_24720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW57_24740	COG2050	protein possibly involved in aromatic compounds catabolism
EXW57_24750	COG1268	BioY protein
EXW57_24755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW57_24760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW57_24770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW57_24775	COG3584	3D domain protein
EXW57_24790	COG1252	NADH dehydrogenase
EXW57_24795	COG0492	ferredoxin-NADP+ reductase activity
EXW57_24800	COG3708	Transcriptional regulator
EXW57_24815	COG1683	Conserved Protein
EXW57_24840	COG0316	Belongs to the HesB IscA family
EXW57_24845	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW57_24850	COG4844	belongs to the
EXW57_24855	COG1252	NADH dehydrogenase
EXW57_24865	COG0390	transport system, permease component
EXW57_24870	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW57_24905	COG4837	Protein of unknown function (DUF1462)
EXW57_24910	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW57_24920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW57_24925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW57_24940	COG0577	efflux transmembrane transporter activity
EXW57_24940	COG1136	(ABC) transporter
EXW57_24945	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW57_24955	COG0647	UMP catabolic process
EXW57_24965	COG2445	Protein of unknown function DUF86
EXW57_24970	COG1494	fructose-1,6-bisphosphatase
EXW57_24985	COG4470	Protein conserved in bacteria
EXW57_24995	COG0789	Transcriptional regulator
EXW57_25000	COG4377	Putative membrane peptidase family (DUF2324)
EXW57_25020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW57_25025	COG0739	heme binding
EXW57_25035	COG3377	Domain of unknown function (DUF1805)
EXW57_25040	COG0737	Belongs to the 5'-nucleotidase family
EXW57_25045	COG0719	Fe-S assembly protein
EXW57_25050	COG0822	iron-sulfur transferase activity
EXW57_25055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW57_25060	COG0719	Fe-S assembly protein
EXW57_25065	COG0396	ATPase activity
EXW57_25070	COG1464	Belongs to the NlpA lipoprotein family
EXW57_25075	COG1464	Belongs to the NlpA lipoprotein family
EXW57_25080	COG2011	ABC-type metal ion transport system permease component
EXW57_25085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW57_25095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW57_25100	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW57_25105	COG0509	glycine decarboxylation via glycine cleavage system
EXW57_25110	COG1393	Belongs to the ArsC family
EXW57_25145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_25150	COG1960	acyl-CoA dehydrogenase activity
EXW57_25155	COG0183	Belongs to the thiolase family
EXW57_25160	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW57_25160	COG1024	Enoyl-CoA hydratase
EXW57_25170	COG1686	Belongs to the peptidase S11 family
EXW57_25175	COG0506	proline dehydrogenase activity
EXW57_25185	COG0011	TIGRFAM Protein of
EXW57_25190	COG0840	transmembrane signaling receptor activity
EXW57_25205	COG2814	Major facilitator Superfamily
EXW57_25210	COG0531	amino acid
EXW57_25235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_25315	COG0586	Pfam SNARE associated Golgi protein
EXW57_25325	COG1376	ErfK ybiS ycfS ynhG family protein
EXW57_25330	COG0745	RESPONSE REGULATOR receiver
EXW57_25335	COG5002	protein histidine kinase activity
EXW57_25345	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW57_25355	COG0840	transmembrane signaling receptor activity
EXW57_25360	COG0840	transmembrane signaling receptor activity
EXW57_25365	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW57_25370	COG3227	Zinc metalloprotease (Elastase)
EXW57_25375	COG1741	Belongs to the pirin family
EXW57_25390	COG0586	Pfam SNARE associated Golgi protein
EXW57_25395	COG0475	glutathione-regulated potassium exporter activity
EXW57_25400	COG0490	domain, Protein
EXW57_25405	COG1115	amino acid carrier protein
EXW57_25410	COG0783	Belongs to the Dps family
EXW57_25425	COG2318	DinB family
EXW57_25430	COG1611	Belongs to the LOG family
EXW57_25440	COG1528	Iron-storage protein
EXW57_25445	COG2311	Membrane
EXW57_25450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_25455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_25460	COG1115	amino acid carrier protein
EXW57_25465	COG1115	amino acid carrier protein
EXW57_25470	COG2910	NAD(P)H-binding
EXW57_25480	COG0656	L-ascorbic acid biosynthetic process
EXW57_25485	COG2814	Major facilitator Superfamily
EXW57_25490	COG1733	regulation of RNA biosynthetic process
EXW57_25500	COG1252	NADH dehydrogenase
EXW57_25520	COG0840	transmembrane signaling receptor activity
EXW57_25520	COG3290	protein histidine kinase activity
EXW57_25555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_25570	COG4224	UPF0291 protein
EXW57_25575	COG1335	isochorismatase
EXW57_25580	COG1522	sequence-specific DNA binding
EXW57_25590	COG1522	sequence-specific DNA binding
EXW57_25595	COG0288	reversible hydration of carbon dioxide
EXW57_25600	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW57_25605	COG2233	PERMEase
EXW57_25645	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW57_25655	COG0557	exoribonuclease II activity
EXW57_25660	COG1647	Serine aminopeptidase, S33
EXW57_25665	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW57_25670	COG1346	cytolysis
EXW57_25685	COG0148	phosphopyruvate hydratase activity
EXW57_25695	COG0149	triose-phosphate isomerase activity
EXW57_25700	COG0126	phosphoglycerate kinase activity
EXW57_25705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW57_25720	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW57_25755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW57_25770	COG2323	membrane
EXW57_25780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW57_25785	COG1481	regulation of sporulation
EXW57_25790	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW57_25795	COG1660	Displays ATPase and GTPase activities
EXW57_25800	COG1051	belongs to the nudix hydrolase family
EXW57_25810	COG0492	ferredoxin-NADP+ reductase activity
EXW57_25815	COG0457	Tetratricopeptide repeat
EXW57_25820	COG0110	maltose O-acetyltransferase activity
EXW57_25825	COG0546	phosphoglycolate phosphatase activity
EXW57_25830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW57_25835	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW57_25840	COG1950	PFAM Membrane protein of
EXW57_25845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW57_25865	COG0789	Transcriptional regulator
EXW57_25900	COG0583	DNA-binding transcription factor activity
EXW57_25905	COG0789	Transcriptional regulator
EXW57_25910	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW57_25915	COG0488	(ABC) transporter
EXW57_25925	COG1132	(ABC) transporter
EXW57_25930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW57_25935	COG0793	Belongs to the peptidase S41A family
EXW57_25935	COG3409	Peptidoglycan-binding domain 1 protein
EXW57_25940	COG2177	Part of the ABC transporter FtsEX involved in
EXW57_25945	COG2884	Cell division ATP-binding protein ftsE
EXW57_25980	COG1131	(ABC) transporter
EXW57_26015	COG1278	Cold shock
EXW57_26020	COG1040	competence protein
EXW57_26025	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW57_26055	COG1388	LysM domain
EXW57_26055	COG0791	NLP P60 protein
EXW57_26060	COG1733	regulation of RNA biosynthetic process
EXW57_26065	COG1307	EDD domain protein, DegV family
EXW57_26070	COG1739	Uncharacterized protein family UPF0029
EXW57_26075	COG1316	TRANSCRIPTIONal
EXW57_26080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW57_26085	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW57_26090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW57_26100	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW57_26100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW57_26120	COG1486	melibiose metabolic process
EXW57_26125	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW57_26130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW57_26150	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW57_26160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW57_26165	COG1301	dicarboxylic acid transport
EXW57_26185	COG1511	domain protein
EXW57_26190	COG0583	DNA-binding transcription factor activity
EXW57_26195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW57_26200	COG1271	oxidase subunit
EXW57_26205	COG1294	oxidase, subunit
EXW57_26210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW57_26215	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW57_26220	COG1620	l-lactate permease
EXW57_26230	COG2389	metal-binding protein
EXW57_26240	COG1368	sulfuric ester hydrolase activity
EXW57_26250	COG1388	LysM domain
EXW57_26250	COG0791	NLP P60 protein
EXW57_26255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_26265	COG1215	transferase activity, transferring glycosyl groups
EXW57_26270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW57_26280	COG1388	LysM domain
EXW57_26280	COG3584	3D domain protein
EXW57_26305	COG4715	Zinc finger, swim domain protein
EXW57_26310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW57_26350	COG0577	efflux transmembrane transporter activity
EXW57_26355	COG1136	(ABC) transporter
EXW57_26390	COG3850	Histidine kinase
EXW57_26390	COG5002	protein histidine kinase activity
EXW57_26395	COG0745	RESPONSE REGULATOR receiver
EXW57_26400	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW57_26420	COG1216	Glycosyl transferase, family 2
EXW57_26420	COG1442	glycosyl transferase family 8
EXW57_26455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW57_26460	COG1086	Polysaccharide biosynthesis protein
EXW57_26465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW57_26470	COG4464	protein tyrosine phosphatase activity
EXW57_26475	COG0489	protein tyrosine kinase activity
EXW57_26480	COG3944	biosynthesis protein
EXW57_26485	COG0489	protein tyrosine kinase activity
EXW57_26500	COG1609	Transcriptional regulator
EXW57_26510	COG0739	heme binding
EXW57_26525	COG3279	Response regulator of the LytR AlgR family
EXW57_26530	COG2385	sporulation resulting in formation of a cellular spore
EXW57_26545	COG4836	Membrane
EXW57_26550	COG1007	ATP synthesis coupled electron transport
EXW57_26555	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW57_26560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW57_26565	COG0713	ATP synthesis coupled electron transport
EXW57_26570	COG0839	Belongs to the complex I subunit 6 family
EXW57_26580	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW57_26585	COG0649	NAD binding
EXW57_26590	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW57_26595	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW57_26600	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW57_26605	COG3300	MHYT domain
EXW57_26605	COG5001	Diguanylate cyclase
EXW57_26620	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW57_26625	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW57_26630	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW57_26635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW57_26640	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW57_26645	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW57_26655	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW57_26680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW57_26690	COG0698	ribose 5-phosphate isomerase
EXW57_26700	COG2190	(PTS) system
EXW57_26705	COG2259	Doxx family
EXW57_26710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW57_26725	COG1971	Probably functions as a manganese efflux pump
EXW57_26730	COG0009	L-threonylcarbamoyladenylate synthase
EXW57_26745	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW57_26750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW57_26755	COG1435	thymidine kinase activity
EXW57_26765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW57_26770	COG1494	fructose-1,6-bisphosphatase
EXW57_26790	COG4821	SIS domain
EXW57_26795	COG0504	CTP synthase activity
EXW57_26800	COG3343	RNA polymerase activity
EXW57_26810	COG1960	acyl-CoA dehydrogenase activity
EXW57_26815	COG1960	acyl-CoA dehydrogenase activity
EXW57_26820	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW57_26825	COG0183	Belongs to the thiolase family
EXW57_26830	COG2181	nitrate reductase activity
EXW57_26830	COG0247	lactate metabolic process
EXW57_26835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW57_26840	COG4294	response to UV
EXW57_26845	COG5001	Diguanylate cyclase
EXW57_26845	COG3300	MHYT domain
EXW57_26860	COG3227	Zinc metalloprotease (Elastase)
EXW57_26865	COG2197	response regulator
EXW57_26870	COG4585	Histidine kinase
EXW57_26875	COG0842	Transport permease protein
EXW57_26880	COG1131	(ABC) transporter
EXW57_26885	COG0024	Methionine aminopeptidase
EXW57_26890	COG2234	aminopeptidase activity
EXW57_26905	COG4506	Protein conserved in bacteria
EXW57_26910	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW57_26930	COG0010	Belongs to the arginase family
EXW57_26935	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW57_26940	COG2814	Major facilitator Superfamily
EXW57_26945	COG0789	Transcriptional regulator
EXW57_26950	COG0584	glycerophosphoryl diester phosphodiesterase
EXW57_26955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW57_26965	COG1994	Peptidase M50
EXW57_26975	COG1078	dGTPase activity
EXW57_26980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_26985	COG1120	ATPase activity
EXW57_26990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_26995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_27000	COG4844	belongs to the
EXW57_27015	COG0280	phosphate acetyltransferase
EXW57_27020	COG3253	May function as heme-dependent peroxidase
EXW57_27030	COG3773	Cell wall hydrolase
EXW57_27040	COG2363	Small membrane protein
EXW57_27055	COG2233	PERMEase
EXW57_27060	COG0561	phosphatase activity
EXW57_27065	COG2814	Major facilitator Superfamily
EXW57_27070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW57_27075	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW57_27080	COG1131	(ABC) transporter
EXW57_27085	COG2755	lipolytic protein G-D-S-L family
EXW57_27090	COG1609	Transcriptional regulator
EXW57_27100	COG0460	homoserine dehydrogenase
EXW57_27105	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW57_27110	COG2873	o-acetylhomoserine
EXW57_27130	COG2197	response regulator
EXW57_27135	COG2203	Gaf domain
EXW57_27135	COG4585	Histidine kinase
EXW57_27140	COG0351	phosphomethylpyrimidine kinase
EXW57_27145	COG3706	GGDEF domain
EXW57_27150	COG2879	small protein
EXW57_27155	COG1966	Carbon starvation protein
EXW57_27160	COG3279	Response regulator of the LytR AlgR family
EXW57_27165	COG0477	Major facilitator Superfamily
EXW57_27190	COG0840	transmembrane signaling receptor activity
EXW57_27200	COG1607	acyl-coa hydrolase
EXW57_27205	COG1216	Glycosyl transferase, family 2
EXW57_27215	COG1216	Glycosyl transferase, family 2
EXW57_27225	COG4485	Bacterial membrane protein, YfhO
EXW57_27230	COG0463	Glycosyl transferase, family 2
EXW57_27240	COG1309	transcriptional regulator
EXW57_27245	COG0488	(ABC) transporter
EXW57_27250	COG1309	transcriptional regulator
EXW57_27255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW57_27260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW57_27260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW57_27265	COG0628	permease
EXW57_27275	COG1380	Effector of murein hydrolase LrgA
EXW57_27280	COG3279	Response regulator of the LytR AlgR family
EXW57_27285	COG3275	phosphorelay sensor kinase activity
EXW57_27290	COG2814	Major facilitator Superfamily
EXW57_27295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW57_27300	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW57_27310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW57_27360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW57_27365	COG1272	protein, Hemolysin III
EXW57_27390	COG1164	Oligoendopeptidase f
EXW57_27400	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW57_27410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW57_27415	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW57_27420	COG4853	Protein conserved in bacteria
EXW57_27430	COG5002	protein histidine kinase activity
EXW57_27435	COG0745	RESPONSE REGULATOR receiver
EXW57_27465	COG0305	Participates in initiation and elongation during chromosome replication
EXW57_27470	COG0359	binds to the 23S rRNA
EXW57_27475	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW57_27480	COG4241	membrane
EXW57_27490	COG0629	single-stranded DNA binding
EXW57_27495	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW57_27500	COG0012	GTP binding
EXW57_27505	COG4481	Protein conserved in bacteria
EXW57_27510	COG0668	transmembrane transport
EXW57_27520	COG1475	DNA binding
EXW57_27525	COG1192	Involved in chromosome partitioning
EXW57_27530	COG1475	DNA binding
EXW57_27535	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW57_27540	COG0445	tRNA wobble uridine modification
EXW57_27545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW57_27550	COG1847	R3H domain protein
EXW57_27555	COG0706	membrane insertase activity
EXW57_27560	COG0594	ribonuclease P activity
EXW57_27565	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW57_27585	COG1278	Cold shock
EXW57_27590	COG0662	Cupin 2, conserved barrel domain protein
EXW57_27635	COG0582	viral genome integration into host DNA
EXW57_27665	COG0488	(ABC) transporter
EXW57_27675	COG1136	(ABC) transporter
EXW57_27680	COG0577	efflux transmembrane transporter activity
EXW57_27700	COG5002	protein histidine kinase activity
EXW57_27745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW57_27760	COG1674	ftsk spoiiie
EXW57_27770	COG0741	lytic transglycosylase activity
EXW57_27780	COG5002	protein histidine kinase activity
EXW57_27785	COG0745	RESPONSE REGULATOR receiver
EXW57_27790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW57_27795	COG0577	efflux transmembrane transporter activity
EXW57_27800	COG1136	(ABC) transporter
EXW57_27935	COG2040	homocysteine
EXW57_27940	COG0833	amino acid
EXW57_27950	COG0756	dUTP diphosphatase activity
EXW57_28025	COG0658	competence protein
EXW57_28025	COG2333	competence protein COMEC
EXW57_28040	COG0825	malonyl-CoA metabolic process
EXW57_28050	COG0640	Transcriptional regulator
EXW57_28070	COG0519	Catalyzes the synthesis of GMP from XMP
EXW57_28140	COG1115	amino acid carrier protein
EXW57_28150	COG1114	Component of the transport system for branched-chain amino acids
EXW57_28155	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW57_28155	COG3409	Peptidoglycan-binding domain 1 protein
EXW57_28160	COG2239	Acts as a magnesium transporter
EXW57_28165	COG0772	Belongs to the SEDS family
EXW57_28175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW57_28190	COG0697	spore germination
EXW57_28240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_28260	COG0662	Cupin 2, conserved barrel domain protein
EXW57_28280	COG0583	DNA-binding transcription factor activity
EXW57_28305	COG4974	Belongs to the 'phage' integrase family
EXW57_28365	COG2211	Major facilitator Superfamily
EXW57_28395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW57_28405	COG2239	Acts as a magnesium transporter
EXW57_28410	COG0772	Belongs to the SEDS family
EXW57_28415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_28420	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW57_28470	COG0697	spore germination
EXW57_28485	COG0662	Cupin 2, conserved barrel domain protein
EXW57_28495	COG0814	amino acid
EXW57_28500	COG1760	l-serine dehydratase
EXW57_28505	COG1760	l-serine dehydratase
EXW57_28515	COG0697	spore germination
EXW57_28520	COG0814	amino acid
EXW57_28540	COG1595	DNA-templated transcription, initiation
EXW57_28600	COG5002	protein histidine kinase activity
EXW57_28615	COG0686	Belongs to the AlaDH PNT family
EXW57_28620	COG2508	Transcriptional regulator
EXW57_28620	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW57_28630	COG2814	Major facilitator Superfamily
EXW57_28635	COG1309	transcriptional regulator
EXW57_28655	COG0083	homoserine kinase activity
EXW57_28710	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW57_28735	COG2814	Major facilitator Superfamily
EXW57_28815	COG1329	Transcriptional regulator
EXW57_28875	COG4176	ABC-type proline glycine betaine transport system permease component
EXW57_28880	COG4175	Glycine betaine
EXW57_28880	COG0517	IMP dehydrogenase activity
EXW57_28900	COG2205	protein histidine kinase activity
EXW57_28905	COG0745	RESPONSE REGULATOR receiver
EXW57_28910	COG0577	efflux transmembrane transporter activity
EXW57_28915	COG1136	(ABC) transporter
EXW57_28955	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW57_28955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW57_28965	COG0772	Belongs to the SEDS family
EXW57_28975	COG0741	lytic transglycosylase activity
EXW57_28995	COG0577	efflux transmembrane transporter activity
EXW57_29000	COG1136	(ABC) transporter
EXW57_29025	COG0789	Transcriptional regulator
EXW57_29030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_29035	COG1923	regulation of RNA biosynthetic process
EXW57_29045	COG2002	toxin-antitoxin pair type II binding
EXW57_29145	COG0791	NLP P60 protein
EXW57_29145	COG3883	PFAM NLP P60 protein
EXW57_29155	COG0741	lytic transglycosylase activity
EXW57_29155	COG0791	NLP P60 protein
EXW57_29240	COG1396	sequence-specific DNA binding
EXW57_29265	COG2186	Transcriptional regulator