locus-tag class description E1A90_00005 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) E1A90_00010 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) E1A90_00025 ENOG41080TC multidrug resistance protein E1A90_00035 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) E1A90_00040 ENOG4105F6J Alpha beta hydrolase fold E1A90_00055 ENOG4105CNI cell division protein FtsW E1A90_00065 ENOG4105CJW magnesium transporter E1A90_00075 ENOG41076HS cation diffusion facilitator family transporter E1A90_00085 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase E1A90_00105 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_00135 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) E1A90_00155 ENOG4105CEY Amp-dependent synthetase and ligase E1A90_00240 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_00245 ENOG4105BZU Histidine kinase E1A90_00250 ENOG4105C0H protease E1A90_00275 ENOG4108J5H Homocysteine s-methyltransferase E1A90_00280 ENOG4108IQI permease E1A90_00295 ENOG4105MDS 4-oxalocrotonate tautomerase E1A90_00300 ENOG4107V2S Transcriptional regulator E1A90_00310 ENOG41067TZ transcriptional regulator, MarR family E1A90_00345 ENOG4105D7V transposase E1A90_00355 ENOG4105CNU cell division protein FtsK E1A90_00370 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) E1A90_00395 ENOG4105F6S Spore photoproduct lyase E1A90_00405 ENOG4105XZV Protein of unknown function (DUF3243) E1A90_00430 ENOG4105WG9 Conserved Protein E1A90_00510 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) E1A90_00595 ENOG41067XF inhibitor E1A90_00625 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving E1A90_00675 ENOG4105EKQ RNA-directed DNA polymerase E1A90_00735 ENOG4108RWP Major Facilitator Superfamily protein E1A90_00740 ENOG4105GZI Transcriptional regulator E1A90_00775 ENOG4107RBB ABC transporter, permease E1A90_00780 ENOG4105C19 ABC transporter E1A90_00800 ENOG4105CKK Glycosyl transferase, family 2 E1A90_00810 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_00815 ENOG4105BZU Histidine kinase E1A90_00840 ENOG41082BM Transcriptional regulator, arsr family E1A90_00880 ENOG4108HJF gCN5-related N-acetyltransferase E1A90_00910 ENOG4107SQ8 Glycine betaine E1A90_00915 ENOG4108IJ7 Glycine betaine E1A90_00945 ENOG4105WQG acetyltransferase E1A90_00960 ENOG4105BZ4 penicillin-binding protein E1A90_01045 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) E1A90_01050 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase E1A90_01060 ENOG4105C5E polysaccharide biosynthesis protein E1A90_01235 ENOG4105EKQ RNA-directed DNA polymerase E1A90_01275 ENOG4105CK5 oxidoreductase E1A90_01280 ENOG4105CK5 oxidoreductase E1A90_01360 ENOG4105CK5 oxidoreductase E1A90_01365 ENOG4105CK5 oxidoreductase E1A90_01405 ENOG4108QY0 Membrane E1A90_01440 ENOG4108W0I acetyltransferase E1A90_01445 ENOG4107QQG Dehydrogenase E1A90_01450 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase E1A90_01455 ENOG4108IAJ Nad-dependent epimerase dehydratase E1A90_01460 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase E1A90_01475 ENOG4105FJR Lmbe family E1A90_01610 ENOG4108WZA zeta toxin E1A90_01635 ENOG4105CAQ asparagine synthetase E1A90_01915 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) E1A90_01980 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein E1A90_02000 ENOG4105WH1 Two component transcriptional regulator luxr family E1A90_02060 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C E1A90_02095 ENOG4105CJW magnesium transporter E1A90_02120 ENOG4108NHD germination protein E1A90_02130 ENOG4105E1K spore germination protein E1A90_02145 ENOG4105CEP NADH dehydrogenase E1A90_02150 ENOG4107TPS domain protein E1A90_02155 ENOG4105KRN Transcriptional regulator, abrb family E1A90_02165 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) E1A90_02235 ENOG4105W8Z 4'-phosphopantetheinyl transferase E1A90_02245 ENOG4105CHR reductase E1A90_02250 ENOG4107EXU Short-chain dehydrogenase reductase Sdr E1A90_02385 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) E1A90_02435 ENOG4105BZU Histidine kinase E1A90_02440 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase E1A90_02460 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) E1A90_02470 ENOG4105D03 DNA-3-methyladenine glycosylase II E1A90_02475 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) E1A90_02485 ENOG4105CGK Exodeoxyribonuclease III E1A90_02505 ENOG4105E0A ABC, transporter E1A90_02510 ENOG4105NIV Esterase E1A90_02530 ENOG4105VPX protein, conserved in bacteria E1A90_02535 ENOG410681U heavy metal transport detoxification protein E1A90_02540 ENOG4105C59 p-type ATPase E1A90_02555 ENOG4105TMB Formate nitrite transporter E1A90_02580 ENOG4105C85 amino acid E1A90_02590 ENOG4108SJC Membrane E1A90_02595 ENOG4107QW4 alcohol dehydrogenase E1A90_02600 ENOG4105E98 transcriptional regulator DeoR family E1A90_02605 ENOG4105DE4 1-phosphofructokinase E1A90_02610 ENOG4105DM4 PTS System E1A90_02615 ENOG41069ER domain protein E1A90_02625 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) E1A90_02650 ENOG4105EN6 Membrane E1A90_02655 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) E1A90_02660 ENOG4105CXI aluminum resistance protein E1A90_02665 ENOG4105KV4 Transcriptional regulator E1A90_02670 ENOG4105C5F glutamine synthetase E1A90_02675 ENOG4105HTX biosynthesis protein E1A90_02680 ENOG4107YJ4 chain length determinant protein E1A90_02690 ENOG4108PQP glycosyl transferase group 1 E1A90_02695 ENOG4108KMV Glycosyl transferase (Group 1 E1A90_02700 ENOG4107SJB teichoic acid biosynthesis E1A90_02710 ENOG4108KMV Glycosyl transferase (Group 1 E1A90_02750 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase E1A90_02785 ENOG4105BZ1 (ABC) transporter E1A90_02790 ENOG4105K7K Transcriptional regulator E1A90_02810 ENOG4108SVB resolvase E1A90_02820 ENOG4105CGH 5'-nucleotidase E1A90_02865 ENOG4105BZ1 (ABC) transporter E1A90_02885 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase E1A90_02910 ENOG41067MG lrgb family E1A90_02920 ENOG4107RSM transcriptional regulator E1A90_02930 ENOG4105CJ1 ABC, transporter E1A90_02935 ENOG4108TU7 Inherit from COG: (ABC) transporter E1A90_02940 ENOG4105CH2 amidohydrolase E1A90_02955 ENOG4107QIV Cytochrome c biogenesis protein E1A90_02990 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) E1A90_03005 ENOG4105CGP Urocanate hydratase E1A90_03015 ENOG4108903 Formimidoylglutamase E1A90_03020 ENOG4108VJ1 Transcriptional regulator (CarD family E1A90_03025 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase E1A90_03030 ENOG4105CBC glutamate synthase E1A90_03035 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase E1A90_03040 ENOG4105FBA Phospholipase Carboxylesterase E1A90_03050 ENOG4105BZU Histidine kinase E1A90_03100 ENOG4108IMY Transcriptional regulator E1A90_03115 ENOG4105CEY Amp-dependent synthetase and ligase E1A90_03120 ENOG4107ZYJ bioY protein E1A90_03125 ENOG4107F3J Amp-dependent synthetase and ligase E1A90_03145 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) E1A90_03155 ENOG4105E5W Transporter E1A90_03185 ENOG4108I0Z Aconitate hydratase E1A90_03190 ENOG4108TYN CAAX amino terminal protease family protein E1A90_03195 ENOG4108JJA ABC, transporter E1A90_03205 ENOG4105D7V transposase E1A90_03220 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen E1A90_03225 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) E1A90_03250 ENOG4105W8X HesB YadR YfhF-family protein E1A90_03260 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase E1A90_03270 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_03275 ENOG4105C0H protease E1A90_03280 ENOG4105K4P CoA-binding domain protein E1A90_03285 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E1A90_03295 ENOG4105D9R oxidoreductase E1A90_03315 ENOG4105CIG ABC transporter E1A90_03325 ENOG4105EMN RNA polymerase sigma factor E1A90_03335 ENOG4108KGH TRANSCRIPTIONal E1A90_03385 ENOG4105CUB amino acid E1A90_03390 ENOG410696E Membrane E1A90_03395 ENOG4105FR1 rard protein E1A90_03405 ENOG4105EWU Squalene--hopene cyclase E1A90_03415 ENOG4105CHR reductase E1A90_03420 ENOG4105C26 Dehydrogenase E1A90_03430 ENOG4108IA2 Sodium pantothenate symporter E1A90_03455 ENOG410904N short-chain dehydrogenase reductase E1A90_03475 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) E1A90_03495 ENOG4105VEQ Cold shock protein E1A90_03510 ENOG4108R1P E1A90_03520 ENOG41073R8 VanW family E1A90_03525 ENOG4108HW4 amino acid AbC transporter E1A90_03535 ENOG4105EAB amino acid AbC transporter E1A90_03540 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase E1A90_03555 ENOG4105KT7 mgtC SapB transporter E1A90_03575 ENOG4105CQB FAD linked oxidase domain protein E1A90_03595 ENOG410780I phosphoprotein phosphatase activity E1A90_03605 ENOG4105CNG UPF0061 protein E1A90_03610 ENOG4105CIS alcohol dehydrogenase E1A90_03615 ENOG41082BM Transcriptional regulator, arsr family E1A90_03660 ENOG4105EGI Transcriptional regulator E1A90_03675 ENOG4108A04 Beta-lactamase E1A90_03690 ENOG4105FFC UPF0187 protein E1A90_03720 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase E1A90_03725 ENOG4105E5K Alpha-amylase E1A90_03730 ENOG4105C98 muts2 protein E1A90_03750 ENOG4107V2S Transcriptional regulator E1A90_03770 ENOG4105NX3 Membrane E1A90_03775 ENOG4105DQ5 transport system permease protein E1A90_03780 ENOG4105EHG Permease protein E1A90_03785 ENOG4108MES Periplasmic binding protein E1A90_03805 ENOG4107R3E Citrate transporter E1A90_03815 ENOG4108TN2 lmbE family E1A90_03855 ENOG4105CIS alcohol dehydrogenase E1A90_03860 ENOG4105K7K Transcriptional regulator E1A90_03905 ENOG4105H3G oxidoreductase E1A90_03945 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) E1A90_03970 ENOG4105C44 Serine transporter E1A90_03990 ENOG4108IND Tetr family transcriptional regulator E1A90_04030 ENOG4105BZU Histidine kinase E1A90_04095 ENOG4108VXD carboxy-peptidase E1A90_04140 ENOG4105KVH Transcriptional regulator E1A90_04145 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein E1A90_04160 ENOG4105JAB phenazine biosynthesis protein, phzf family E1A90_04220 ENOG4105C44 Serine transporter E1A90_04235 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase E1A90_04250 ENOG4105CMG Carbohydrate kinase E1A90_04255 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) E1A90_04260 ENOG4105XDF Protein of unknown function (DUF1272) E1A90_04265 ENOG4105DDN Pentapeptide repeat-containing protein E1A90_04300 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase E1A90_04315 ENOG4105C37 (CBS) domain E1A90_04345 ENOG4105EV4 Multidrug resistance protein mdtH E1A90_04355 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) E1A90_04360 ENOG4108R96 Methyltransferase, YaeB family E1A90_04370 ENOG4107BMA Transglycosylase associated protein E1A90_04385 ENOG4105C31 Tryptophanyl-tRNA synthetase E1A90_04390 ENOG4108UW5 maltose o-acetyltransferase E1A90_04400 ENOG4105DKQ ROK family E1A90_04405 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase E1A90_04445 ENOG4108AEY RNA polymerase sigma factor E1A90_04485 ENOG4108PSK reductase E1A90_04505 ENOG4105KVH Transcriptional regulator E1A90_04510 ENOG4108RCM Nitroreductase E1A90_04515 ENOG4105G6Z alkaline phosphatase E1A90_04535 ENOG4108Z66 YbaK ebsC protein E1A90_04555 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) E1A90_04560 ENOG4108K8S endonuclease I E1A90_04595 ENOG4108JJB ABC transporter E1A90_04635 ENOG4105DYS nad(p)h dehydrogenase (quinone) E1A90_04645 ENOG4105CRW Short chain fatty acid transporter E1A90_04725 ENOG4105ETE Transcriptional regulator (LacI family E1A90_04730 ENOG4105IE8 Alpha-ketoglutarate permease E1A90_04740 ENOG4105CK5 oxidoreductase E1A90_04765 ENOG4105D2N Aldolase E1A90_04770 ENOG4105DH8 myo-inositol catabolism E1A90_04820 ENOG4105DYB Isoaspartyl dipeptidase E1A90_04885 ENOG4105CZM Major Facilitator E1A90_04890 ENOG4107MII Sugar-specific transcriptional regulator TrmB E1A90_04920 ENOG4105PNM synthesis protein E1A90_04925 ENOG4108VXD carboxy-peptidase E1A90_04975 ENOG4108IG5 Transcriptional regulator E1A90_05000 ENOG4105WH1 Two component transcriptional regulator luxr family E1A90_05020 ENOG4105YWU small acid-soluble spore protein E1A90_05045 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) E1A90_05050 ENOG4108JQ1 Dehydrogenase E1A90_05070 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A E1A90_05105 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) E1A90_05115 ENOG4105BZU Histidine kinase E1A90_05140 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) E1A90_05160 ENOG4105JQZ Methyltransferase E1A90_05175 ENOG4105E0Y RtcB Protein E1A90_05210 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase E1A90_05230 ENOG4105VZ8 Transcriptional regulator E1A90_05260 ENOG4105K6H D-cysteine desulfhydrase E1A90_05290 ENOG41062D9 Histidine kinase E1A90_05295 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_05325 ENOG4105C0R drug resistance transporter emrb qaca subfamily E1A90_05330 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) E1A90_05420 ENOG4108YXU transcriptional regulator AsnC family E1A90_05425 ENOG4105CHR reductase E1A90_05430 ENOG4108IG5 Transcriptional regulator E1A90_05435 ENOG4107P5I polyketide synthase E1A90_05445 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) E1A90_05465 ENOG41085FC arsR family transcriptional regulator E1A90_05470 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase E1A90_05475 ENOG4105D6J arsenicaL-resistance protein E1A90_05505 ENOG4107ZQN disulfide bond E1A90_05510 ENOG4108KF3 Electron transport protein SCO1 SenC E1A90_05525 ENOG4105DIK (ABC) transporter E1A90_05530 ENOG4105CC5 ABC transporter E1A90_05535 ENOG4105DSE periplasmic solute binding protein E1A90_05585 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase E1A90_05595 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_05600 ENOG4105BZU Histidine kinase E1A90_05605 ENOG4107VMI polysaccharide deacetylase E1A90_05635 ENOG4107TSN permease E1A90_05650 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) E1A90_05680 ENOG4105DWD nucleoside recognition domain protein E1A90_05690 ENOG41082BM Transcriptional regulator, arsr family E1A90_05715 ENOG4105FDT acyl-CoA dehydrogenase E1A90_05735 ENOG4107258 Transcriptional regulator E1A90_05740 ENOG4105P4J Allophanate hydrolase, subunit 1 E1A90_05750 ENOG4105E7W lamb ycsf family protein E1A90_05765 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) E1A90_05785 ENOG4105DUX Transporter E1A90_05790 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) E1A90_05795 ENOG4107RF6 penicillin-binding protein E1A90_05840 ENOG4108IQI permease E1A90_05850 ENOG410635A Membrane E1A90_05875 ENOG4105RHY Pfam:UPF0157 E1A90_05910 ENOG4108PCN EamA-like transporter family E1A90_05925 ENOG4108XET gCN5-related N-acetyltransferase E1A90_05930 ENOG4108DMH HTH_ARAC E1A90_05955 ENOG4105WEC Molybdate metabolism regulator E1A90_05980 ENOG4105FS7 Transcriptional regulator E1A90_05985 ENOG4108TVJ Nitroreductase E1A90_06025 ENOG4105CH6 catalase E1A90_06030 ENOG4105C8Y Acetylornithine aminotransferase E1A90_06050 ENOG4105C7R Atpase associated with various cellular activities aaa_3 E1A90_06080 ENOG41068WN E1A90_06125 ENOG4105VMP Transcriptional regulator E1A90_06140 ENOG4105ECK Fatty Acid Desaturase E1A90_06145 ENOG4105II7 pyrroline-5-carboxylate reductase E1A90_06150 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) E1A90_06155 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) E1A90_06190 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) E1A90_06195 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase E1A90_06210 ENOG4108I0C methyltransferase E1A90_06215 ENOG41061GT Aldolase E1A90_06230 ENOG4105DKT Transcriptional regulator E1A90_06250 ENOG4105D4B ABC, transporter E1A90_06255 ENOG4105DWT malate dehydrogenase (quinone) E1A90_06285 ENOG4108YYH Nadph-dependent fmn reductase E1A90_06295 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase E1A90_06305 ENOG41069ER domain protein E1A90_06355 ENOG4105C0I Conserved Protein E1A90_06380 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase E1A90_06385 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase E1A90_06415 ENOG41082JN Transcriptional regulator E1A90_06425 ENOG4105EYF MMPL domain protein E1A90_06430 ENOG4105C5H ABC transporter E1A90_06450 ENOG4105C0R drug resistance transporter emrb qaca subfamily E1A90_06465 ENOG4107VMI polysaccharide deacetylase E1A90_06515 ENOG4108AQF aminoglycoside N(3)-acetyltransferase E1A90_06560 ENOG4105C02 permease E1A90_06610 ENOG4105DVE abc transporter atp-binding protein E1A90_06640 ENOG4105CHM Aminotransferase E1A90_06675 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) E1A90_06690 ENOG4107BMA Transglycosylase associated protein E1A90_06710 ENOG4106K7D Major facilitator family transporter E1A90_06715 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) E1A90_06750 ENOG4105CHJ isochorismatase hydrolase E1A90_06785 ENOG4105EPR degv family E1A90_06800 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 E1A90_06815 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_06820 ENOG4105BZU Histidine kinase E1A90_06825 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) E1A90_06865 ENOG4105CPC Aldo Keto reductase E1A90_06885 ENOG4105DTQ mandelate racemase muconate lactonizing E1A90_06900 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD E1A90_06915 ENOG4107T5V SNARE associated Golgi E1A90_06945 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein E1A90_06955 ENOG41080HI glycine oxidase E1A90_06960 ENOG4105CTU Proline racemase E1A90_06965 ENOG4105CTU Proline racemase E1A90_06970 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) E1A90_06975 ENOG4105C26 Dehydrogenase E1A90_07010 ENOG4108M1A Chitin-binding protein E1A90_07015 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase E1A90_07045 ENOG4105C9U ATP-dependent DNA helicase RecQ E1A90_07085 ENOG4108Z7F N-acetyltransferase E1A90_07110 ENOG4105MSB protein, conserved in bacteria E1A90_07130 ENOG41087PP glycosyltransferase MGT family E1A90_07140 ENOG4108M1A Chitin-binding protein E1A90_07145 ENOG41082BV acetyltransferase E1A90_07150 ENOG4105E66 phosphoriboisomerase A E1A90_07175 ENOG4108IJ7 Glycine betaine E1A90_07180 ENOG4107SQ8 Glycine betaine E1A90_07215 ENOG4105RHY Pfam:UPF0157 E1A90_07220 ENOG4105E1F short-chain dehydrogenase reductase E1A90_07230 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) E1A90_07255 ENOG41062ES Transcriptional regulator E1A90_07275 ENOG4105E98 transcriptional regulator DeoR family E1A90_07305 ENOG4107Z3H Transcriptional regulator, TetR family E1A90_07310 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) E1A90_07315 ENOG4106IPI cyclase, family E1A90_07320 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) E1A90_07350 ENOG4105MSI germination protein ypeb E1A90_07395 ENOG4105CIS alcohol dehydrogenase E1A90_07430 ENOG4105CPC Aldo Keto reductase E1A90_07475 ENOG4105D6E homoserine dehydrogenase E1A90_07490 ENOG4105ETU transcriptional activator (TenA E1A90_07500 ENOG4105VTR Integrase E1A90_07520 ENOG4108JCI Transcriptional regulator E1A90_07545 ENOG4105KRN Transcriptional regulator, abrb family E1A90_07645 ENOG4105CAR Terminase, large subunit E1A90_07655 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) E1A90_07740 ENOG4105F6S Spore photoproduct lyase E1A90_07760 ENOG4108606 TspO/MBR family E1A90_07860 ENOG410667J hydrolase E1A90_07865 ENOG4105BZU Histidine kinase E1A90_07870 ENOG4107RF6 penicillin-binding protein E1A90_07890 ENOG4108V7D UPF0397 protein E1A90_07895 ENOG4108JJB ABC transporter E1A90_07910 ENOG4108HGU Histidine kinase E1A90_07925 ENOG4105CB2 alcohol dehydrogenase E1A90_07930 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase E1A90_07935 ENOG4105CJN penicillin-binding protein E1A90_07970 ENOG4105BZ1 (ABC) transporter E1A90_07990 ENOG4107Y80 Major Facilitator superfamily E1A90_08015 ENOG4107VXM glycerophosphoryl diester phosphodiesterase E1A90_08035 ENOG4107Y9U Membrane E1A90_08075 ENOG4105FCD Major Facilitator E1A90_08085 ENOG4105E09 nadh pyrophosphatase E1A90_08090 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) E1A90_08125 ENOG4108XI2 Domain of unknown function (DUF1963) E1A90_08150 ENOG4108NRW Phospholipase, patatin family E1A90_08155 ENOG4105KWG Pfam:DUF1696 E1A90_08190 ENOG4105PKS Excinuclease abc c subunit domain protein E1A90_08210 ENOG4107RA9 decarboxylase E1A90_08215 ENOG4105BZ1 (ABC) transporter E1A90_08225 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase E1A90_08230 ENOG4107VFR oxidoreductase E1A90_08255 ENOG4105U0R haloacid dehalogenase-like hydrolase E1A90_08260 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_08325 ENOG4108IUM Glycogen debranching enzyme E1A90_08335 ENOG4105CGH 5'-nucleotidase E1A90_08345 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) E1A90_08350 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) E1A90_08355 ENOG4105FDR Membrane E1A90_08420 ENOG4105SX7 Transporter E1A90_08450 ENOG4105J7D transcriptional regulator E1A90_08475 ENOG4105KVH Transcriptional regulator E1A90_08480 ENOG4105CHR reductase E1A90_08505 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) E1A90_08535 ENOG41075H3 AraC family transcriptional regulator E1A90_08555 ENOG4105DQ6 Transposase E1A90_08580 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) E1A90_08655 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) E1A90_08660 ENOG4107QX3 carboxylase E1A90_08665 ENOG4105E39 Enoyl-CoA hydratase E1A90_08675 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit E1A90_08680 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase E1A90_08685 ENOG4105C1G acyl-Coa dehydrogenase E1A90_08705 ENOG4105CJ1 ABC, transporter E1A90_08725 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C E1A90_08730 ENOG4108M1A Chitin-binding protein E1A90_08760 ENOG4105E1K spore germination protein E1A90_08775 ENOG4107TPS domain protein E1A90_08780 ENOG4105CEP NADH dehydrogenase E1A90_08825 ENOG4107RF6 penicillin-binding protein E1A90_08840 ENOG4105EMN RNA polymerase sigma factor E1A90_08925 ENOG4105C19 ABC transporter E1A90_08965 ENOG4105EQK -acetyltransferase E1A90_08970 ENOG4105CIN aminoacyl-histidine dipeptidase E1A90_08990 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) E1A90_09010 ENOG41088CC tellurite resistance protein tehB E1A90_09030 ENOG4108RZE Tetr family transcriptional regulator E1A90_09035 ENOG4105C1J atp-dependent rna helicase E1A90_09085 ENOG4107STF Involved in phosphonate degradation (By similarity) E1A90_09095 ENOG4105RD7 BadF BadG BcrA BcrD E1A90_09100 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) E1A90_09120 ENOG4105F32 YngK protein E1A90_09140 ENOG4108KPJ rna polymerase sigma factor E1A90_09145 ENOG4108KJ0 anaerobic glycerol-3-phosphate dehydrogenase, subunit B E1A90_09185 ENOG4108JCI Transcriptional regulator E1A90_09205 ENOG4105BZ1 (ABC) transporter E1A90_09210 ENOG4105BZ1 (ABC) transporter E1A90_09230 ENOG4108JPW Aminotransferase E1A90_09235 ENOG4107RSM transcriptional regulator E1A90_09280 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) E1A90_09285 ENOG4107V2S Transcriptional regulator E1A90_09315 ENOG41068WN E1A90_09325 ENOG4105C1Q protoporphyrinogen oxidase E1A90_09370 ENOG4105WCN acetyltransferase E1A90_09395 ENOG4105EYF MMPL domain protein E1A90_09400 ENOG41067SE Tetr family transcriptional regulator E1A90_09420 ENOG4107MII Sugar-specific transcriptional regulator TrmB E1A90_09440 ENOG4108Y4K DNA-binding transcriptional activator E1A90_09450 ENOG41081I9 integral membrane protein E1A90_09470 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) E1A90_09475 ENOG4105C37 (CBS) domain E1A90_09525 ENOG4105C19 ABC transporter E1A90_09535 ENOG4105VMP Transcriptional regulator E1A90_09540 ENOG4105C22 threonyL-tRNA synthetase E1A90_09545 ENOG4105FE9 pseudouridine synthase E1A90_09580 ENOG4105K70 DNA-binding protein E1A90_09595 ENOG4105C0R drug resistance transporter emrb qaca subfamily E1A90_09605 ENOG4105CEY Amp-dependent synthetase and ligase E1A90_09610 ENOG4105WQI isochorismatase E1A90_09615 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase E1A90_09620 ENOG4105E4F Isochorismate synthase E1A90_09625 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase E1A90_09630 ENOG4105FCD Major Facilitator E1A90_09650 ENOG4107RFY SbcCD D subunit E1A90_09670 ENOG4105N14 lysine exporter protein LysE YggA E1A90_09680 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase E1A90_09690 ENOG4105CR4 methylisocitrate lyase E1A90_09695 ENOG4105DXD 2-methylcitrate dehydratase E1A90_09710 ENOG4105CZM Major Facilitator E1A90_09720 ENOG4105BZ4 penicillin-binding protein E1A90_09740 ENOG4105CHR reductase E1A90_09775 ENOG4105F0F Oxalate decarboxylase E1A90_09810 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) E1A90_09890 ENOG4105SZ6 Thioredoxin E1A90_09940 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein E1A90_09945 ENOG4108JUB Transcriptional regulator E1A90_09950 ENOG4108TSC N-acetyltransferase E1A90_09955 ENOG4107S4Y M20 DapE family protein YgeY E1A90_09970 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) E1A90_10030 ENOG4105E90 ABC transporter E1A90_10055 ENOG4105C6Z Gluconate E1A90_10060 ENOG4105CMG Carbohydrate kinase E1A90_10080 ENOG4106KNT transcriptional regulator E1A90_10085 ENOG4105WH1 Two component transcriptional regulator luxr family E1A90_10090 ENOG4105BZU Histidine kinase E1A90_10130 ENOG4105F0I Aminotransferase E1A90_10135 ENOG4108MES Periplasmic binding protein E1A90_10140 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase E1A90_10155 ENOG4105CAQ asparagine synthetase E1A90_10160 ENOG4107Y70 Heat shock protein E1A90_10165 ENOG4108KF3 Electron transport protein SCO1 SenC E1A90_10170 ENOG4105E8R UPF0173 metal-dependent hydrolase E1A90_10185 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) E1A90_10190 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) E1A90_10195 ENOG4108UT2 hemolysin iii E1A90_10200 ENOG4105E9Q Acyl-transferase E1A90_10245 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 E1A90_10265 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase E1A90_10270 ENOG4105KD7 acetyltransferase E1A90_10290 ENOG4105CY2 Citrate transporter E1A90_10300 ENOG4107XGZ Hydrolase E1A90_10320 ENOG4105C8J )-transporter E1A90_10400 ENOG4105C5S asparaginyl-tRNA synthetase E1A90_10440 ENOG4105DA6 Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity) E1A90_10455 ENOG4105C75 arginyL-tRNA synthetase E1A90_10460 ENOG4107YX5 Pfam:DUF548 E1A90_10480 ENOG4108UUM single-stranded DNA-binding protein E1A90_10510 ENOG4105MCT stage V sporulation protein S E1A90_10540 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) E1A90_10545 ENOG4108IFG nitrite reductase, (NAD(P)H) E1A90_10550 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit E1A90_10555 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) E1A90_10560 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein E1A90_10565 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein E1A90_10575 ENOG4105GAK amidohydrolase 2 E1A90_10595 ENOG4108ZAF Molybdopterin E1A90_10600 ENOG4105CVM Molybdenum cofactor synthesis domain protein E1A90_10605 ENOG4105D06 uba thif-type nad fad binding protein E1A90_10610 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) E1A90_10625 ENOG4105R3A Nitrate reductase E1A90_10630 ENOG4108IUE nitrate reductase beta subunit E1A90_10650 ENOG4105C7R Atpase associated with various cellular activities aaa_3 E1A90_10670 ENOG4108V06 Glutathione peroxidase E1A90_10680 ENOG4105CNW domain protein E1A90_10705 ENOG4105EMN RNA polymerase sigma factor E1A90_10710 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein E1A90_10740 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) E1A90_10765 ENOG4105KBJ sporulation protein ytfj E1A90_10835 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) E1A90_10865 ENOG4108JYZ YitT family E1A90_10870 ENOG41087PP glycosyltransferase MGT family E1A90_10905 ENOG41082F9 transcriptional regulator E1A90_10910 ENOG4108X4Q Hydrolase E1A90_10920 ENOG4108ZRV stage ii sporulation protein p E1A90_10945 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) E1A90_10950 ENOG4108VXD carboxy-peptidase E1A90_10965 ENOG4108ZRV stage ii sporulation protein p E1A90_10985 ENOG4108Z7R Chaperone CsaA E1A90_11015 ENOG4105C37 (CBS) domain E1A90_11020 ENOG4105SXS Protein of unknown function (DUF456) E1A90_11055 ENOG4108S4H thioesterase Superfamily protein E1A90_11065 ENOG4108PJD permease E1A90_11080 ENOG4107T5V SNARE associated Golgi E1A90_11100 ENOG4107TB6 phosphoglycerate mutase E1A90_11125 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) E1A90_11130 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase E1A90_11145 ENOG4105DSE periplasmic solute binding protein E1A90_11155 ENOG4105CKI cobalamin synthesis protein E1A90_11160 ENOG4107QM2 Aldo Keto reductase E1A90_11165 ENOG4105VMI -acetyltransferase E1A90_11180 ENOG4105DEN Luciferase family E1A90_11195 ENOG4108WPJ Ferritin-like domain E1A90_11245 ENOG4107XZQ multidrug resistance protein E1A90_11255 ENOG4105YVS arsR family transcriptional regulator E1A90_11265 ENOG4105KRN Transcriptional regulator, abrb family E1A90_11315 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family E1A90_11320 ENOG4108ZUB Lysine exporter protein (Lyse ygga) E1A90_11330 ENOG4105YWU small acid-soluble spore protein E1A90_11335 ENOG4108WBH protein TIM barrel E1A90_11350 ENOG4105CEY Amp-dependent synthetase and ligase E1A90_11355 ENOG4105DUU IucA IucC family protein E1A90_11365 ENOG4105VRR gCN5-related N-acetyltransferase E1A90_11370 ENOG4105KT7 mgtC SapB transporter E1A90_11385 ENOG4108KGH TRANSCRIPTIONal E1A90_11400 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) E1A90_11410 ENOG4105D6E homoserine dehydrogenase E1A90_11435 ENOG41075D4 Aminoglycoside 6-adenylyltransferase E1A90_11440 ENOG4108VQJ O-methyltransferase E1A90_11450 ENOG4105BZU Histidine kinase E1A90_11455 ENOG4105EFI regulatoR E1A90_11515 ENOG4108JJ8 (ABC) transporter E1A90_11520 ENOG4108JJ9 ABC, transporter E1A90_11525 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii E1A90_11555 ENOG4105MDS 4-oxalocrotonate tautomerase E1A90_11565 ENOG410825D TRANSCRIPTIONal REGULATOR, LysR family E1A90_11575 ENOG4105C32 Amino acid ABC transporter (Permease) E1A90_11580 ENOG4108IV0 ABC, transporter E1A90_11585 ENOG4105C0Z ABC transporter E1A90_11595 ENOG4105CKI cobalamin synthesis protein E1A90_11605 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) E1A90_11615 ENOG4106F5Q Membrane E1A90_11620 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) E1A90_11635 ENOG4108TVJ Nitroreductase E1A90_11640 ENOG4107ZXU DSBA oxidoreductase E1A90_11645 ENOG4108Z40 Transcriptional regulator E1A90_11650 ENOG4105GZI Transcriptional regulator E1A90_11655 ENOG4107RT3 EamA-like transporter family E1A90_11725 ENOG4107TUM Amidinotransferase E1A90_11770 ENOG4107R16 Multicopper oxidase E1A90_11775 ENOG4107RAQ aminopeptidase E1A90_11795 ENOG410811B TRANSCRIPTIONal E1A90_11830 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) E1A90_11835 ENOG4105D9N nucleoside E1A90_11840 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) E1A90_11850 ENOG4107RHR regulatoR E1A90_11855 ENOG4105F9V Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid E1A90_11865 ENOG4105KNA -acetyltransferase E1A90_11870 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) E1A90_11885 ENOG410829K Lysine exporter protein (Lyse ygga) E1A90_11905 ENOG4105C0X amino acid E1A90_11910 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) E1A90_11920 ENOG4105C72 UPF0176 protein E1A90_11925 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) E1A90_11945 ENOG41068WN E1A90_12030 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b E1A90_12035 ENOG4105C6X Major Facilitator E1A90_12055 ENOG4105C7B Threonine dehydratase E1A90_12065 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase E1A90_12075 ENOG4105C7K acetolactate synthase E1A90_12080 ENOG4105CM2 brancheD-chain amino acid aminotransferase E1A90_12085 ENOG4105CHR reductase E1A90_12090 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_12095 ENOG4105BZU Histidine kinase E1A90_12110 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) E1A90_12115 ENOG4105D3R alkyl hydroperoxide reductase E1A90_12120 ENOG4108IQI permease E1A90_12135 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein E1A90_12145 ENOG4108UW5 maltose o-acetyltransferase E1A90_12150 ENOG4105KVH Transcriptional regulator E1A90_12165 ENOG4105H67 Protein of unknown function (DUF421) E1A90_12170 ENOG4105X5K response regulator receiver protein E1A90_12180 ENOG4105C8J )-transporter E1A90_12195 ENOG4105C6T cysteine synthase E1A90_12205 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) E1A90_12225 ENOG4105DXI Major Facilitator superfamily E1A90_12235 ENOG4105CSR polyphosphate kinase 2 E1A90_12265 ENOG4105FVX E1A90_12305 ENOG4105CU9 asparagine synthetase A E1A90_12345 ENOG4105C6K Malic enzyme E1A90_12350 ENOG4108IJ0 Aspartate ammonia-lyase E1A90_12360 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) E1A90_12385 ENOG4105CJ1 ABC, transporter E1A90_12430 ENOG4106BRA Membrane E1A90_12435 ENOG4105BZC d-serine deaminase E1A90_12450 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen E1A90_12455 ENOG4107QIV Cytochrome c biogenesis protein E1A90_12475 ENOG4105EC3 peptidase S51, dipeptidase E E1A90_12480 ENOG4107QJQ Mate efflux family protein E1A90_12505 ENOG4105C9Q fumarate hydratase class II E1A90_12510 ENOG4105DFD Na H antiporter E1A90_12520 ENOG4108UZ3 Transporter E1A90_12525 ENOG4105DRR Transcriptional regulator, GntR family E1A90_12535 ENOG4105PGM cation diffusion facilitator family transporter E1A90_12555 ENOG4105CAQ asparagine synthetase E1A90_12585 ENOG4105CVJ phosphoglycerate mutase E1A90_12635 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component E1A90_12650 ENOG4105DUM transcriptional regulator, lysR family E1A90_12675 ENOG4105KAC Antibiotic biosynthesis monooxygenase E1A90_12710 ENOG4105CPU Monooxygenase E1A90_12715 ENOG4105KTQ flagellar basal-body rod protein E1A90_12725 ENOG4105D7B Flagellar biosynthesis protein flha E1A90_12730 ENOG4105D00 flagellar biosynthetic protein flhB E1A90_12740 ENOG4105VS8 Flagellar biosynthetic protein fliq E1A90_12745 ENOG4105CN7 Flagellar biosynthetic protein FliP E1A90_12755 ENOG4105DD5 Flagellar motor switch protein E1A90_12760 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) E1A90_12770 ENOG4105E4C Lytic transglycosylase catalytic E1A90_12775 ENOG4105I03 Flagellin E1A90_12785 ENOG4105D1F ATP-binding protein E1A90_12795 ENOG4108ZAF Molybdopterin E1A90_12800 ENOG4105CVM Molybdenum cofactor synthesis domain protein E1A90_12805 ENOG4105D06 uba thif-type nad fad binding protein E1A90_12810 ENOG4105TMB Formate nitrite transporter E1A90_12820 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) E1A90_12825 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) E1A90_12835 ENOG4108JB9 formate dehydrogenase E1A90_12850 ENOG4105BZU Histidine kinase E1A90_12870 ENOG4107R88 Chemotaxis protein (CheV) E1A90_12885 ENOG4105BZE flagellar hook protein, FlgE E1A90_12915 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) E1A90_12920 ENOG4107U2N Flagellar M-ring protein E1A90_12925 ENOG41075Z6 flagellar hook-basal body complex protein fliE E1A90_12930 ENOG4108ZC9 flagellar basal-body rod protein flgc E1A90_12935 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) E1A90_12955 ENOG4105DTS flagellar hook-associated E1A90_12960 ENOG4105DTJ flagellar hook-associated protein E1A90_12965 ENOG4105E1Q flagellar hook-associated protein E1A90_12985 ENOG4105BZU Histidine kinase E1A90_13000 ENOG4105DD5 Flagellar motor switch protein E1A90_13010 ENOG4107YTP response regulator receiver protein E1A90_13015 ENOG4105ER2 Ompa motb domain protein E1A90_13020 ENOG4107R0U MotA TolQ exbB proton channel E1A90_13030 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) E1A90_13075 ENOG41080C8 DUF218 domain E1A90_13080 ENOG4105H67 Protein of unknown function (DUF421) E1A90_13090 ENOG4108Z5V transcriptional regulator, merr family E1A90_13095 ENOG4107RWR Sodium hydrogen exchanger E1A90_13190 ENOG4108SZE gCN5-related N-acetyltransferase E1A90_13245 ENOG4105KHC sulfurtransferase E1A90_13255 ENOG4108W0I acetyltransferase E1A90_13275 ENOG4105DHF Membrane E1A90_13280 ENOG4105C2W permease E1A90_13285 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) E1A90_13290 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) E1A90_13300 ENOG4105CTD carboxy-peptidase E1A90_13305 ENOG4105DVT helicase E1A90_13315 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) E1A90_13325 ENOG4105XWG Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity) E1A90_13330 ENOG4108UKS UPF0398 protein E1A90_13380 ENOG4105CSM endonuclease III E1A90_13400 ENOG4105YAC E1A90_13405 ENOG4105DVT helicase E1A90_13415 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) E1A90_13420 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) E1A90_13430 ENOG4105DJ0 Poly(A) Polymerase E1A90_13435 ENOG4105CPK Glycosyl transferase (Group 1 E1A90_13440 ENOG4105FJR Lmbe family E1A90_13445 ENOG4108Z5K methylglyoxal synthase E1A90_13450 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) E1A90_13455 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase E1A90_13460 ENOG4108JYZ YitT family E1A90_13495 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit E1A90_13500 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) E1A90_13505 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) E1A90_13520 ENOG41068YB TPR repeat-containing protein E1A90_13525 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase E1A90_13535 ENOG4105D49 3-dehydroquinate synthase E1A90_13540 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase E1A90_13545 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) E1A90_13550 ENOG4105EAH synthase E1A90_13555 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) E1A90_13560 ENOG4105XXQ heptaprenyl diphosphate synthase component I E1A90_13575 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) E1A90_13595 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase E1A90_13600 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) E1A90_13605 ENOG41065D1 E1A90_13640 ENOG4105CAT Cytidine monophosphate kinase E1A90_13645 ENOG4107RB3 L-asparaginase E1A90_13650 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase E1A90_13675 ENOG4108S6Z Negative regulator of genetic competence E1A90_13680 ENOG4107X2D transcriptional regulator, merr family E1A90_13695 ENOG4105I7S Abortive infection protein E1A90_13705 ENOG4105T7X E1A90_13720 ENOG4108SAX Membrane E1A90_13730 ENOG41063SB peptidase E1A90_13745 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_13750 ENOG4105CRE cytochrome C E1A90_13755 ENOG4107TWT Cytochrome c biogenesis protein E1A90_13765 ENOG4105FE9 pseudouridine synthase E1A90_13775 ENOG4108JIC nucleoside recognition domain protein E1A90_13780 ENOG4105DZ1 carboxypeptidase E1A90_13815 ENOG4105BZU Histidine kinase E1A90_13830 ENOG4105I3N Conserved Protein E1A90_13835 ENOG4105BZU Histidine kinase E1A90_13850 ENOG4105BZ4 penicillin-binding protein E1A90_13855 ENOG4107GRR phosphate transport regulator E1A90_13860 ENOG4105CJ3 phosphate transporter E1A90_13930 ENOG4105WH1 Two component transcriptional regulator luxr family E1A90_13955 ENOG4105DFD Na H antiporter E1A90_13975 ENOG4105C8J )-transporter E1A90_13990 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein E1A90_13995 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) E1A90_14005 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) E1A90_14010 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) E1A90_14015 ENOG4107RIQ Sulfate adenylate transferase E1A90_14020 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) E1A90_14030 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) E1A90_14040 ENOG4105E0M Sulfatase E1A90_14045 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase E1A90_14060 ENOG4107RVV histidinol phosphate phosphatase, hisj family E1A90_14065 ENOG4105KPZ phosphoribosyl-atp pyrophosphatase E1A90_14075 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) E1A90_14080 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase E1A90_14085 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) E1A90_14100 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) E1A90_14105 ENOG4108IQ6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) E1A90_14115 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) E1A90_14125 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) E1A90_14135 ENOG4108ZP8 Acetolactate synthase small subunit E1A90_14140 ENOG4105C7K acetolactate synthase E1A90_14145 ENOG4105CM2 brancheD-chain amino acid aminotransferase E1A90_14170 ENOG4105KBJ sporulation protein ytfj E1A90_14180 ENOG4105CZN Potassium uptake protein E1A90_14215 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) E1A90_14220 ENOG4107QMU Mate efflux family protein E1A90_14245 ENOG4105NQC Flavodoxin E1A90_14265 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein E1A90_14270 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) E1A90_14275 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD E1A90_14280 ENOG4105EA8 2-Nitropropane dioxygenase E1A90_14285 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A E1A90_14325 ENOG4105CJ1 ABC, transporter E1A90_14340 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family E1A90_14345 ENOG4105C8Y Acetylornithine aminotransferase E1A90_14350 ENOG4105C26 Dehydrogenase E1A90_14355 ENOG4108JUB Transcriptional regulator E1A90_14370 ENOG4105CUB amino acid E1A90_14375 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) E1A90_14390 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) E1A90_14410 ENOG4108R6G acetyltransferase E1A90_14425 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) E1A90_14430 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) E1A90_14435 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase E1A90_14440 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) E1A90_14445 ENOG4105BZU Histidine kinase E1A90_14460 ENOG41090MY MarR family Transcriptional regulator E1A90_14485 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) E1A90_14505 ENOG4107QMX Aminotransferase E1A90_14510 ENOG4108KAZ Involved in phosphonate degradation (By similarity) E1A90_14525 ENOG4105C4Y ABC transporter E1A90_14555 ENOG4105CHR reductase E1A90_14580 ENOG410681C small acid-soluble spore protein E1A90_14585 ENOG4105CZN Potassium uptake protein E1A90_14595 ENOG4108QTI )-transporter E1A90_14605 ENOG4106A3R peptidase E1A90_14615 ENOG4107QR9 Iron-sulfur cluster binding protein E1A90_14625 ENOG4105JXH GntR family transcriptional regulator E1A90_14635 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_14650 ENOG4105CQB FAD linked oxidase domain protein E1A90_14655 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) E1A90_14660 ENOG4105K4I Scp-like extracellular E1A90_14670 ENOG4108YBP pseudouridine synthase E1A90_14680 ENOG4105EYF MMPL domain protein E1A90_14690 ENOG4107RUE extracellular solute-binding protein family 1 E1A90_14695 ENOG4105D38 putrescine abc transporter E1A90_14700 ENOG4105F38 ABC transporter, permease E1A90_14710 ENOG4105C26 Dehydrogenase E1A90_14745 ENOG4105VFR signal peptidase E1A90_14750 ENOG4105DZ1 carboxypeptidase E1A90_14780 ENOG4105RHA ABC transporter, permease E1A90_14785 ENOG4108IUX (ABC) transporter E1A90_14815 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 E1A90_14820 ENOG4105C7S Dehydrogenase E1A90_14890 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) E1A90_14895 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) E1A90_14900 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase E1A90_14910 ENOG4108I0Q anthranilate phosphoribosyltransferase E1A90_14915 ENOG4105DDQ anthranilate synthase E1A90_14920 ENOG4105CRQ synthase (Component I) E1A90_14930 ENOG4105CK7 Sodium proline symporter E1A90_15015 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase E1A90_15025 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase E1A90_15030 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) E1A90_15050 ENOG4107TVC Glycosyl transferase, family 2 E1A90_15070 ENOG4105K64 Glycosyl transferase, family 2 E1A90_15095 ENOG4105EMS pseudouridine synthase E1A90_15100 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) E1A90_15115 ENOG4105MIX Adenylate cyclase E1A90_15120 ENOG4108Z18 K06886 hemoglobin E1A90_15130 ENOG4105DPN Oligoendopeptidase f E1A90_15140 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) E1A90_15150 ENOG4108ZCF integral membrane protein E1A90_15170 ENOG4105UQX Mate efflux family protein E1A90_15175 ENOG4108JQ7 (ABC) transporter E1A90_15190 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E1A90_15210 ENOG4105C31 Tryptophanyl-tRNA synthetase E1A90_15225 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) E1A90_15230 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) E1A90_15265 ENOG4108KP7 hydrolase E1A90_15280 ENOG4107AYK membrAne E1A90_15330 ENOG4105CNA YD repeat protein E1A90_15335 ENOG4105QNR S1 RNA binding domain protein E1A90_15340 ENOG4108VPT UPF0234 protein E1A90_15345 ENOG4107A6P E1A90_15355 ENOG4105BZU Histidine kinase E1A90_15360 ENOG4105CH6 catalase E1A90_15370 ENOG4105CAQ asparagine synthetase E1A90_15395 ENOG4105ERH Fumarylacetoacetate hydrolase E1A90_15445 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation E1A90_15450 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination E1A90_15470 ENOG4105XVF Competence transcription factor E1A90_15500 ENOG4107QP3 malate synthase g E1A90_15520 ENOG4105C8Q Methyl-accepting chemotaxis E1A90_15525 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 E1A90_15545 ENOG4105DPZ Two component transcriptional regulator (Winged helix family E1A90_15555 ENOG41086D8 Transcriptional regulator E1A90_15565 ENOG4108AEY RNA polymerase sigma factor E1A90_15580 ENOG4107TVP HD domain protein E1A90_15680 ENOG4105ECW sulfate abc transporter E1A90_15685 ENOG4108I5D sulfate abc transporter E1A90_15690 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein E1A90_15700 ENOG4105CEY Amp-dependent synthetase and ligase E1A90_15710 ENOG4105DF9 Lipoate-protein, ligase E1A90_15715 ENOG4108RQ5 Beta-lactamase domain-containing protein E1A90_15760 ENOG4105ECB domain protein E1A90_15790 ENOG4105C1Q protoporphyrinogen oxidase E1A90_15800 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) E1A90_15805 ENOG4105BZ4 penicillin-binding protein E1A90_15810 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation E1A90_15815 ENOG4105CKV Membrane E1A90_15820 ENOG410905X membrane-flanked domain protein E1A90_15835 ENOG4105DUY Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein E1A90_15860 ENOG4105CKV Membrane E1A90_15865 ENOG410905X membrane-flanked domain protein E1A90_15880 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) E1A90_15890 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) E1A90_15910 ENOG4105K59 histidine triad (HIT) protein E1A90_15935 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) E1A90_15940 ENOG4105EEM helicase E1A90_15955 ENOG4105EMN RNA polymerase sigma factor E1A90_15970 ENOG4105C6V Glycerol-3-phosphate dehydrogenase E1A90_15975 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) E1A90_15985 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator E1A90_15990 ENOG41067QW Transcriptional regulator E1A90_16000 ENOG4108MUZ hydrolase E1A90_16040 ENOG4105C7R Atpase associated with various cellular activities aaa_3 E1A90_16045 ENOG4105EQI Metal Dependent Phosphohydrolase E1A90_16050 ENOG4106D4I domain protein E1A90_16055 ENOG4107VRP DNA repair exonuclease E1A90_16085 ENOG4108VB1 regulatoR E1A90_16090 ENOG4105ENE Histidine kinase E1A90_16095 ENOG4105C6F GntR Family Transcriptional Regulator E1A90_16100 ENOG4105DJ2 Major Facilitator Superfamily E1A90_16130 ENOG4105BZU Histidine kinase E1A90_16135 ENOG4105BZU Histidine kinase E1A90_16140 ENOG4108MJI response regulator E1A90_16150 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E1A90_16160 ENOG4105WN5 stage II sporulation protein E1A90_16220 ENOG4105C19 ABC transporter E1A90_16275 ENOG4105C19 ABC transporter E1A90_16285 ENOG4105EWM Histidine kinase E1A90_16315 ENOG4107RBI VanW family E1A90_16330 ENOG4105FBW Monooxygenase E1A90_16375 ENOG4105CMT Dihydroxyacetone kinase E1A90_16400 ENOG4105WAB arsR family transcriptional regulator E1A90_16405 ENOG4105F27 Major Facilitator E1A90_16410 ENOG41067XF inhibitor E1A90_16470 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase E1A90_16520 ENOG4105C0R drug resistance transporter emrb qaca subfamily E1A90_16545 ENOG4105CDU Replicative dna helicase E1A90_16635 ENOG4108MRH transcriptional regulatory protein E1A90_16645 ENOG4105CSH Transporter E1A90_16690 ENOG4108JQ7 (ABC) transporter E1A90_16695 ENOG4105C3U ABC transporter E1A90_16700 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E1A90_16725 ENOG4108JUB Transcriptional regulator E1A90_16730 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) E1A90_16735 ENOG4105D5U fad dependent oxidoreductase E1A90_16775 ENOG4105DER m42 family E1A90_16795 ENOG4105CGU Enoyl-CoA hydratase E1A90_16820 ENOG4105CHH sulfate transporter E1A90_16830 ENOG4105CEY Amp-dependent synthetase and ligase E1A90_16835 ENOG4105D4P Coproporphyrinogen iii oxidase E1A90_16840 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase E1A90_16855 ENOG4108VX5 3-methyladenine DNA glycosylase E1A90_16860 ENOG4107R51 Glycosyl transferase, family 2 E1A90_16865 ENOG4106WTF Glycosyl transferase, family 2 E1A90_16870 ENOG4107FQX Alpha-acetolactate decarboxylase E1A90_16895 ENOG4105WZB UPF0342 protein E1A90_16900 ENOG4108UH6 UPF0754 membrane protein E1A90_16910 ENOG410839P E1A90_16925 ENOG4105CDA abc transporter atp-binding protein E1A90_16930 ENOG4105DRP amino acid AbC transporter E1A90_16940 ENOG4105BZ1 (ABC) transporter E1A90_16945 ENOG4105BZ1 (ABC) transporter E1A90_16960 ENOG4105C26 Dehydrogenase E1A90_16965 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) E1A90_16970 ENOG4105D5Q Arginine ornithine antiporter E1A90_16980 ENOG4107RKG DJ-1/PfpI family E1A90_16990 ENOG4105E5W Transporter E1A90_16995 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) E1A90_17000 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF E1A90_17030 ENOG4105KPY Small multidrug resistance protein E1A90_17035 ENOG4105KPY Small multidrug resistance protein E1A90_17045 ENOG4108IXY short-chain dehydrogenase reductase E1A90_17055 ENOG4108YXU transcriptional regulator AsnC family E1A90_17060 ENOG4108PCN EamA-like transporter family E1A90_17095 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate E1A90_17100 ENOG4106KNT transcriptional regulator E1A90_17110 ENOG4107RWR Sodium hydrogen exchanger E1A90_17115 ENOG4105CUB amino acid E1A90_17145 ENOG4107T5V SNARE associated Golgi E1A90_17175 ENOG4105WEF catalase E1A90_17210 ENOG4105C19 ABC transporter E1A90_17215 ENOG4107RBB ABC transporter, permease E1A90_17220 ENOG41069ER domain protein E1A90_17245 ENOG4105VZJ PTS System E1A90_17250 ENOG4105VCP PTS System E1A90_17275 ENOG4105EE1 crotonyl-CoA reductase E1A90_17290 ENOG4108KGH TRANSCRIPTIONal E1A90_17300 ENOG41087NI Sulfite exporter TauE/SafE E1A90_17305 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase E1A90_17310 ENOG4105VFE sira family E1A90_17315 ENOG4105VFE sira family E1A90_17320 ENOG4107TPS domain protein E1A90_17330 ENOG4105XTG Pfam:DUF156 E1A90_17370 ENOG4107Y03 Nitroreductase E1A90_17390 ENOG4108B31 Spore germination protein E1A90_17410 ENOG4105K63 Thioredoxin E1A90_17425 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein E1A90_17435 ENOG4105C7N Xanthine uracil vitamin C permease E1A90_17450 ENOG4105CNN ABC, transporter E1A90_17470 ENOG4108INS Transcriptional regulator E1A90_17485 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) E1A90_17490 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) E1A90_17520 ENOG4105DWF phosphomethylpyrimidine kinase E1A90_17525 ENOG4105D06 uba thif-type nad fad binding protein E1A90_17540 ENOG41080HI glycine oxidase E1A90_17545 ENOG4108VEU Thiamine monophosphate synthase E1A90_17565 ENOG4105ETU transcriptional activator (TenA E1A90_17570 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase E1A90_17585 ENOG41080XQ Signal transduction protein with cbs domains E1A90_17715 ENOG4105E2Z phosphate ABC transporter (Permease E1A90_17720 ENOG4105C8U phosphate abc transporter E1A90_17725 ENOG4105CVA phosphate E1A90_17735 ENOG4105CE1 Ferrous iron transport protein b E1A90_17740 ENOG4105CE1 Ferrous iron transport protein b E1A90_17750 ENOG4108NHD germination protein E1A90_17765 ENOG4105E1V na solute symporter E1A90_17770 ENOG4106CAD Protein of unknown function (DUF3311) E1A90_17785 ENOG4108IQI permease E1A90_17790 ENOG4105E2S oxidase) subunit II E1A90_17795 ENOG4105BZ9 Cytochrome C oxidase, subunit I E1A90_17800 ENOG4105CCU oxidase (Subunit III) E1A90_17840 ENOG4105C7N Xanthine uracil vitamin C permease E1A90_17845 ENOG4105C85 amino acid E1A90_17865 ENOG4105DUX Transporter E1A90_17885 ENOG4105VZ8 Transcriptional regulator E1A90_17890 ENOG41069ER domain protein E1A90_17895 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer E1A90_17900 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) E1A90_17925 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) E1A90_17965 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) E1A90_17970 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator E1A90_17975 ENOG4105CNN ABC, transporter E1A90_17985 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) E1A90_17990 ENOG4108RVA ribokinase E1A90_17995 ENOG4105ETE Transcriptional regulator (LacI family E1A90_18000 ENOG4105C0R drug resistance transporter emrb qaca subfamily E1A90_18005 ENOG41067TZ transcriptional regulator, MarR family E1A90_18010 ENOG4105CXY transporter E1A90_18020 ENOG4108JQ7 (ABC) transporter E1A90_18025 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E1A90_18035 ENOG4105DEF Extracellular solute-binding protein, family 5 E1A90_18045 ENOG41068KF Universal stress protein E1A90_18065 ENOG4105BZU Histidine kinase E1A90_18070 ENOG4105NAE bifunctional deaminase-reductase domain protein E1A90_18105 ENOG4108IQI permease E1A90_18110 ENOG4105DRP amino acid AbC transporter E1A90_18115 ENOG4105EAD ABC transporter E1A90_18120 ENOG4105CT1 (ABC) transporter E1A90_18125 ENOG4105CDA abc transporter atp-binding protein E1A90_18130 ENOG4105BZG amino acid carrier protein E1A90_18135 ENOG4105CRN Aminoglycoside phosphotransferase E1A90_18150 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin E1A90_18160 ENOG4108XG2 Histidine kinase E1A90_18165 ENOG4105E1K spore germination protein E1A90_18185 ENOG4105CG3 alpha amylase, catalytic region E1A90_18190 ENOG4105C5Y PTS System E1A90_18195 ENOG4107414 GntR family transcriptional regulator E1A90_18200 ENOG4105D5Q Arginine ornithine antiporter E1A90_18205 ENOG4105BZU Histidine kinase E1A90_18220 ENOG4105GMT ATPase associated with various cellular activities aaa_5 E1A90_18235 ENOG4105EXW epimerase dehydratase E1A90_18240 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) E1A90_18245 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) E1A90_18255 ENOG4105E0A ABC, transporter E1A90_18260 ENOG4108IHU transport system permease protein E1A90_18265 ENOG4105DQ5 transport system permease protein E1A90_18270 ENOG4108MES Periplasmic binding protein E1A90_18275 ENOG4105DUX Transporter E1A90_18295 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen E1A90_18305 ENOG4108IJ0 Aspartate ammonia-lyase E1A90_18310 ENOG4105C37 (CBS) domain E1A90_18315 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase E1A90_18320 ENOG4105D9N nucleoside E1A90_18325 ENOG4108KGH TRANSCRIPTIONal E1A90_18330 ENOG41073R8 VanW family E1A90_18365 ENOG4105DAP Nicotinate phosphoribosyltransferase E1A90_18370 ENOG4105C59 p-type ATPase E1A90_18385 ENOG4105CUB amino acid E1A90_18405 ENOG4108JB9 formate dehydrogenase E1A90_18410 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) E1A90_18415 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) E1A90_18420 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_18425 ENOG4105BZU Histidine kinase E1A90_18435 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family E1A90_18440 ENOG4108UZ3 Transporter E1A90_18450 ENOG4105C6K Malic enzyme E1A90_18460 ENOG4108MRH transcriptional regulatory protein E1A90_18485 ENOG4105US7 Histidine kinase E1A90_18490 ENOG4108STX response regulator E1A90_18495 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) E1A90_18500 ENOG4105BZ7 extracellular solute-binding protein family 1 E1A90_18505 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component E1A90_18520 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator E1A90_18545 ENOG4105D4T Citrate transporter E1A90_18550 ENOG4108V9W transcriptional regulatory protein E1A90_18555 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism E1A90_18565 ENOG4105DZ6 Band 7 protein E1A90_18585 ENOG4106AKX UPF0229 protein E1A90_18600 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) E1A90_18610 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) E1A90_18620 ENOG4107ZQN disulfide bond E1A90_18625 ENOG4108JQC penicillin-binding protein 1A E1A90_18745 ENOG4105G5W regulator Fur family E1A90_18750 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen E1A90_18770 ENOG4108IUW ABC transporter E1A90_18785 ENOG4107NBY Membrane E1A90_18790 ENOG4105BZ1 (ABC) transporter E1A90_18815 ENOG4105CEN a g-specific adenine glycosylase E1A90_18855 ENOG4105CI2 imidazolone-5-propionate hydrolase E1A90_18875 ENOG4105F1A Pyruvate formate-lyase E1A90_18890 ENOG4105CKK Glycosyl transferase, family 2 E1A90_18900 ENOG4107QQG Dehydrogenase E1A90_18905 ENOG4107R51 Glycosyl transferase, family 2 E1A90_18920 ENOG4108A04 Beta-lactamase E1A90_18935 ENOG4105CSV Glutaminase E1A90_18970 ENOG4108JUB Transcriptional regulator E1A90_18980 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) E1A90_19020 ENOG4105UPD Calcium Proton E1A90_19025 ENOG410606W general stress protein E1A90_19040 ENOG4107ZTW SNARE associated Golgi E1A90_19060 ENOG4108IPJ Membrane E1A90_19065 ENOG4105C59 p-type ATPase E1A90_19070 ENOG4107U9T Pfam:Ribonuclease_BN E1A90_19080 ENOG4105KJF protein tyrosine phosphatase E1A90_19100 ENOG4108TTB tellurium resistance protein E1A90_19110 ENOG4106FN3 tellurium resistance protein E1A90_19115 ENOG4106FN3 tellurium resistance protein E1A90_19120 ENOG4108N0M stress protein E1A90_19150 ENOG4105DEU major facilitator superfamily E1A90_19165 ENOG41062JF Transcriptional regulator E1A90_19195 ENOG4105C5H ABC transporter E1A90_19210 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component E1A90_19230 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter E1A90_19240 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase E1A90_19245 ENOG4105C9U ATP-dependent DNA helicase RecQ E1A90_19260 ENOG4105CI1 PTS System E1A90_19270 ENOG4105DNP FAD linked oxidase domain protein E1A90_19285 ENOG4105C5B carbamate kinase E1A90_19310 ENOG4105C8Q Methyl-accepting chemotaxis E1A90_19325 ENOG4105E5Q amino acid AbC transporter E1A90_19340 ENOG4105D2S major facilitator superfamily E1A90_19345 ENOG410756H nucleotidyltransferase E1A90_19365 ENOG4105BZU Histidine kinase E1A90_19380 ENOG4106UIA E1A90_19385 ENOG4106UIA E1A90_19400 ENOG4105CAY ferredoxin--nadp reductase E1A90_19410 ENOG4108V5C ABC transporter E1A90_19415 ENOG4105DQ5 transport system permease protein E1A90_19420 ENOG4105EHG Permease protein E1A90_19430 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) E1A90_19435 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) E1A90_19440 ENOG4105D3R alkyl hydroperoxide reductase E1A90_19460 ENOG4105DFD Na H antiporter E1A90_19470 ENOG4105DTQ mandelate racemase muconate lactonizing E1A90_19485 ENOG4108W15 Protein of unknown function (DUF1456) E1A90_19500 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) E1A90_19505 ENOG4105D9N nucleoside E1A90_19530 ENOG4105C26 Dehydrogenase E1A90_19545 ENOG4108JPW Aminotransferase E1A90_19550 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) E1A90_19555 ENOG4105CBD Diacylglycerol kinase E1A90_19560 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) E1A90_19565 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) E1A90_19575 ENOG4107I77 yiaA/B two helix domain E1A90_19580 ENOG41067TZ transcriptional regulator, MarR family E1A90_19600 ENOG4105D01 (LipO)protein E1A90_19605 ENOG4108UMI ABC transporter, permease E1A90_19635 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) E1A90_19670 ENOG4105C12 Phosphoribosylglycinamide synthetase E1A90_19680 ENOG4105DC1 bifunctional purine biosynthesis protein purh E1A90_19685 ENOG4108V3E phosphoribosylglycinamide formyltransferase E1A90_19690 ENOG4105CXB phosphoribosylaminoimidazole synthetase E1A90_19705 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I E1A90_19710 ENOG4105VR9 phosphoribosylformylglycinamidine synthase E1A90_19715 ENOG4105C8V SAICAR synthetase E1A90_19720 ENOG4105C83 adenylosuccinate lyase E1A90_19725 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit E1A90_19730 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) E1A90_19760 ENOG4105SX7 Transporter E1A90_19780 ENOG4105DPZ Two component transcriptional regulator (Winged helix family E1A90_19850 ENOG4107ZXU DSBA oxidoreductase E1A90_19880 ENOG4105BZU Histidine kinase E1A90_19890 ENOG4105C7N Xanthine uracil vitamin C permease E1A90_19895 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) E1A90_19900 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) E1A90_19905 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) E1A90_19910 ENOG4108TYN CAAX amino terminal protease family protein E1A90_19925 ENOG4105C5H ABC transporter E1A90_19935 ENOG410801F ribosomal-protein-alanine acetyltransferase E1A90_19945 ENOG4105K8N protein family UPF0079, ATPase E1A90_20050 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) E1A90_20060 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) E1A90_20065 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein E1A90_20070 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) E1A90_20090 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) E1A90_20100 ENOG4108SC4 )-transporter E1A90_20105 ENOG4105CUB amino acid E1A90_20115 ENOG4105ERH Fumarylacetoacetate hydrolase E1A90_20120 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase E1A90_20150 ENOG410667J hydrolase E1A90_20155 ENOG4108JQ7 (ABC) transporter E1A90_20160 ENOG4105C3U ABC transporter E1A90_20180 ENOG4105DEF Extracellular solute-binding protein, family 5 E1A90_20190 ENOG4108KYE ABC-2 type transporter E1A90_20200 ENOG4105CJ1 ABC, transporter E1A90_20205 ENOG4105WH1 Two component transcriptional regulator luxr family E1A90_20210 ENOG4105BZU Histidine kinase E1A90_20215 ENOG4105C5H ABC transporter E1A90_20255 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) E1A90_20275 ENOG4105F6E Acyl-transferase E1A90_20305 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family E1A90_20310 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein E1A90_20315 ENOG4105E0C molybdate abc transporter E1A90_20325 ENOG4106Z1T Nicotinamide Mononucleotide Transporter E1A90_20330 ENOG4105II7 pyrroline-5-carboxylate reductase E1A90_20340 ENOG4108J59 Extracellular solute-binding protein, family 5 E1A90_20345 ENOG4108J59 Extracellular solute-binding protein, family 5 E1A90_20375 ENOG4108JQ7 (ABC) transporter E1A90_20380 ENOG4105C3U ABC transporter E1A90_20385 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E1A90_20390 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E1A90_20410 ENOG4105C2C drug resistance transporter, Bcr CflA E1A90_20425 ENOG4105IQ5 FAD linked oxidase domain protein E1A90_20435 ENOG4105EE1 crotonyl-CoA reductase E1A90_20440 ENOG4105D01 (LipO)protein E1A90_20450 ENOG4108UMI ABC transporter, permease E1A90_20455 ENOG4108PSK reductase E1A90_20495 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) E1A90_20505 ENOG4105C8B TIGR00159 family E1A90_20585 ENOG4108NMV polysaccharide deacetylase E1A90_20600 ENOG4105D1F ATP-binding protein E1A90_20615 ENOG4108UJD 30S ribosomal protein S9 E1A90_20620 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) E1A90_20625 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) E1A90_20630 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) E1A90_20655 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) E1A90_20665 ENOG41067V7 50S ribosomal protein L36 E1A90_20675 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) E1A90_20685 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) E1A90_20690 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) E1A90_20695 ENOG4105VPB 50S ribosomal protein L30 E1A90_20705 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) E1A90_20710 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) E1A90_20715 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) E1A90_20725 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits E1A90_20730 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) E1A90_20745 ENOG41082SA 50s ribosomal protein l29 E1A90_20760 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) E1A90_20765 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) E1A90_20770 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity E1A90_20780 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) E1A90_20795 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) E1A90_20800 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) E1A90_20815 ENOG4105XPM ribosomal protein E1A90_20820 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) E1A90_20825 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) E1A90_20830 ENOG4107Y49 methyltransferase E1A90_20835 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) E1A90_20840 ENOG4108VZM 50s ribosomal protein L10 E1A90_20845 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) E1A90_20855 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) E1A90_20870 ENOG4105QIV RNA polymerase E1A90_20880 ENOG4105C2N RNA methyltransferase TrmH family group 3 E1A90_20890 ENOG4105C8N cysteinyl-tRNA synthetase E1A90_20895 ENOG4105D7W serine acetyltransferase E1A90_20900 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) E1A90_20910 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) E1A90_20920 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) E1A90_20925 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) E1A90_20940 ENOG4108Z0C Uvrb UvrC protein E1A90_21030 ENOG4105CRK lysyL-tRNA synthetase E1A90_21035 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) E1A90_21045 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase E1A90_21050 ENOG4105KRF dihydroneopterin aldolase E1A90_21055 ENOG4105EEI dihydropteroate synthase E1A90_21060 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 E1A90_21065 ENOG4105DDQ anthranilate synthase E1A90_21070 ENOG4105CRQ synthase (Component I) E1A90_21075 ENOG4105C6T cysteine synthase E1A90_21080 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) E1A90_21085 ENOG4105CGM Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) E1A90_21090 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) E1A90_21095 ENOG4108UGV hypoxanthine phosphoribosyltransferase E1A90_21135 ENOG4105VYY sporulation protein yabp E1A90_21140 ENOG41082I2 s4 domain protein E1A90_21155 ENOG4108M14 stage v sporulation protein t E1A90_21175 ENOG4105C5T Phosphoribosyl pyrophosphate synthase E1A90_21180 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) E1A90_21190 ENOG4105KME endoribonuclease L-psp E1A90_21195 ENOG4105DFT pur operon repressor E1A90_21200 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) E1A90_21210 ENOG4105W42 Veg protein E1A90_21215 ENOG4105XFA sporulation peptidase YabG E1A90_21220 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) E1A90_21225 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) E1A90_21230 ENOG4105F8V Hydrolase, tatD family E1A90_21235 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) E1A90_21240 ENOG4105KRN Transcriptional regulator, abrb family E1A90_21245 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) E1A90_21250 ENOG41060K3 Methyltransferase E1A90_21260 ENOG4105MA4 psp1 domain protein E1A90_21265 ENOG4105FA2 dna polymerase iii E1A90_21270 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) E1A90_21275 ENOG4105CXN decarboxylase E1A90_21310 ENOG41067KS pro-sigma K processing E1A90_21320 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) E1A90_21325 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) E1A90_21330 ENOG4105C6E dna polymerase iii E1A90_21340 ENOG4108Z6B deaminase E1A90_21345 ENOG4105GTG Isochorismatase E1A90_21355 ENOG4105ZMH deoxynucleoside kinase E1A90_21375 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) E1A90_21380 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) E1A90_21390 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) E1A90_21435 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) E1A90_21440 ENOG410848D S4 domain protein YaaA E1A90_21445 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) E1A90_21465 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins E1A90_21475 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) E1A90_21480 ENOG4105CWE NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) E1A90_21490 ENOG410636K Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity) E1A90_21500 ENOG4105FA0 parb-like partition protein E1A90_21505 ENOG4108ZDA Sporulation protein YyaC E1A90_21510 ENOG4105D8X mechanosensitive ion channel E1A90_21515 ENOG4105VDK protein, conserved in bacteria E1A90_21520 ENOG4105C3G gtp-binding protein E1A90_21525 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) E1A90_21530 ENOG4108UUM single-stranded DNA-binding protein E1A90_21550 ENOG4105K9Q Binds to the 23S rRNA (By similarity) E1A90_21555 ENOG4105CDU Replicative dna helicase E1A90_21560 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis E1A90_21585 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_21590 ENOG4105BZU Histidine kinase E1A90_21605 ENOG4105Q2H domain protein E1A90_21620 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) E1A90_21635 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) E1A90_21650 ENOG4105C1J atp-dependent rna helicase E1A90_21660 ENOG4108UT2 hemolysin iii E1A90_21665 ENOG4105CMR udp-glucose 4-epimerase E1A90_21705 ENOG4105IW1 AmiS UreI transporter E1A90_21715 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) E1A90_21735 ENOG4107RGD Major Facilitator superfamily E1A90_21740 ENOG4108HRK Histidine kinase E1A90_21745 ENOG4105DY9 regulatoR E1A90_21750 ENOG41083D3 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses (By similarity) E1A90_21755 ENOG41067MG lrgb family E1A90_21760 ENOG4106F5Q Membrane E1A90_21765 ENOG4105E0X reductase E1A90_21775 ENOG41067SE Tetr family transcriptional regulator E1A90_21785 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein E1A90_21790 ENOG4105C5H ABC transporter E1A90_21795 ENOG4107S6X Glycosyl transferase, family 2 E1A90_21810 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) E1A90_21815 ENOG4108S4H thioesterase Superfamily protein E1A90_21825 ENOG4106YBV Methyl-accepting chemotaxis E1A90_21855 ENOG41079KZ Major Facilitator Superfamily E1A90_21860 ENOG4105DY9 regulatoR E1A90_21865 ENOG4105D22 carbon starvation protein E1A90_21870 ENOG4105VCD cytoplasmic protein E1A90_21875 ENOG4105BZU Histidine kinase E1A90_21885 ENOG4105BZU Histidine kinase E1A90_21890 ENOG4105WH1 Two component transcriptional regulator luxr family E1A90_21915 ENOG4105CVG Homoserine O-transsuccinylase E1A90_21920 ENOG4105D6E homoserine dehydrogenase E1A90_21935 ENOG41090WU lipolytic protein G-D-S-L family E1A90_21940 ENOG4105CJ1 ABC, transporter E1A90_21945 ENOG4108TU7 Inherit from COG: (ABC) transporter E1A90_21950 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) E1A90_21955 ENOG4105VCH membrane E1A90_21960 ENOG410667J hydrolase E1A90_21990 ENOG4108VKI Cell wall hydrolase E1A90_22000 ENOG4107JTW chlorite dismutase E1A90_22005 ENOG4108IJ2 phosphate acetyltransferase E1A90_22010 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) E1A90_22015 ENOG4108VCI transcription factor, rsfa family E1A90_22025 ENOG4105DQ5 transport system permease protein E1A90_22030 ENOG4105EHG Permease protein E1A90_22035 ENOG4105E0A ABC, transporter E1A90_22040 ENOG4108MES Periplasmic binding protein E1A90_22045 ENOG4105DCI Phosphohydrolase E1A90_22050 ENOG41069HH 4-oxalocrotonate tautomerase E1A90_22055 ENOG4108Z4T Peptidase M50 E1A90_22060 ENOG4108XFG YwhD family E1A90_22065 ENOG4105BZ4 penicillin-binding protein E1A90_22070 ENOG4108QXE glycerophosphoryl diester phosphodiesterase E1A90_22075 ENOG4107SWG transcriptional regulator MERR family E1A90_22080 ENOG4105DXB Major Facilitator superfamily E1A90_22090 ENOG4105CYW agmatinase E1A90_22110 ENOG410684U Domain of unknown function (DUF1934) E1A90_22125 ENOG4105IIU Aminopeptidase E1A90_22135 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) E1A90_22140 ENOG4108M15 ABC transporter E1A90_22145 ENOG4105KCT ABC transporter E1A90_22180 ENOG4105BZU Histidine kinase E1A90_22195 ENOG4105DF6 Fe-S oxidoreductase E1A90_22210 ENOG4105C1G acyl-Coa dehydrogenase E1A90_22215 ENOG4105C1G acyl-Coa dehydrogenase E1A90_22260 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) E1A90_22270 ENOG4107104 thymidine kinase E1A90_22280 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) E1A90_22285 ENOG4108ZXQ stage ii sporulation protein r E1A90_22310 ENOG4107XC4 flavin reductase domain protein, FMN-binding E1A90_22315 ENOG4108VGI doxx family E1A90_22330 ENOG4108YZG isomerase E1A90_22340 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) E1A90_22365 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) E1A90_22375 ENOG4107ZFM Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity) E1A90_22385 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) E1A90_22390 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) E1A90_22395 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) E1A90_22420 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain E1A90_22425 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) E1A90_22430 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain E1A90_22435 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) E1A90_22440 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) E1A90_22455 ENOG4105M5H NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) E1A90_22460 ENOG4105D65 subunit l E1A90_22465 ENOG4105C8S subunit m E1A90_22470 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) E1A90_22475 ENOG4106778 Protein of unknown function (DUF1146) E1A90_22495 ENOG4105DY9 regulatoR E1A90_22510 ENOG4105FRN stage II sporulation protein E1A90_22525 ENOG4105MT0 Sporulation transcriptional regulator spoiiid E1A90_22540 ENOG4108QV3 biosynthesis protein E1A90_22550 ENOG4107YJ4 chain length determinant protein E1A90_22555 ENOG4108RB3 Capsular polysaccharide biosynthesis protein E1A90_22560 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase E1A90_22590 ENOG4105C6Y Udp-glucose 6-dehydrogenase E1A90_22595 ENOG4105CMR udp-glucose 4-epimerase E1A90_22610 ENOG4105CMR udp-glucose 4-epimerase E1A90_22615 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_22620 ENOG41062D9 Histidine kinase E1A90_22635 ENOG4105CXY transporter E1A90_22645 ENOG4105C19 ABC transporter E1A90_22650 ENOG4107RBB ABC transporter, permease E1A90_22665 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E1A90_22695 ENOG4105C0D helicase E1A90_22700 ENOG4105KBK Zinc finger, swim domain protein E1A90_22725 ENOG41069ER domain protein E1A90_22735 ENOG4105C94 Transporter E1A90_22740 ENOG4107R8N Glycosyl transferase, family 2 E1A90_22765 ENOG4105E0M Sulfatase E1A90_22780 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) E1A90_22795 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) E1A90_22820 ENOG4107RSM transcriptional regulator E1A90_22825 ENOG4105ECB domain protein E1A90_22850 ENOG4105VZJ PTS System E1A90_22860 ENOG4105VCP PTS System E1A90_22870 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) E1A90_22885 ENOG4105CK1 PTS System E1A90_22890 ENOG4105VCP PTS System E1A90_22895 ENOG4105F8D glycoside hydrolase family 4 E1A90_22915 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family E1A90_22925 ENOG4105ESV Glycosyl transferase, family 4 E1A90_22930 ENOG4105C6Y Udp-glucose 6-dehydrogenase E1A90_22935 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase E1A90_22945 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein E1A90_22955 ENOG4105KVH Transcriptional regulator E1A90_22970 ENOG41081UC Inherit from COG: Competence protein E1A90_22975 ENOG4105VEQ Cold shock protein E1A90_22980 ENOG4105MS2 ribosomal subunit Interface protein E1A90_23015 ENOG4105CAK Cell division ATP-binding protein ftsE E1A90_23020 ENOG4105CRP Part of the ABC transporter FtsEX involved in E1A90_23025 ENOG4105CN1 protease E1A90_23035 ENOG4105BZ1 (ABC) transporter E1A90_23050 ENOG4108WS4 fmn reductase E1A90_23055 ENOG4108Z6Z Transcriptional regulator E1A90_23060 ENOG4105DUM transcriptional regulator, lysR family E1A90_23095 ENOG4107TXC Transcriptional regulator E1A90_23125 ENOG41086DT Membrane protein of unknown function E1A90_23130 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) E1A90_23135 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) E1A90_23140 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) E1A90_23145 ENOG4108S4C acetyltransferase E1A90_23155 ENOG4105C3M thioredoxin reductase E1A90_23165 ENOG4108Z4K mutator MutT protein E1A90_23170 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) E1A90_23175 ENOG4105CHW UPF0052 protein E1A90_23180 ENOG4105CIE May be required for sporulation (By similarity) E1A90_23185 ENOG4105KRI phosphocarrier protein (HPr E1A90_23190 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) E1A90_23210 ENOG4105CZ3 stage V sporulation protein ad E1A90_23215 ENOG41090VF Stage v sporulation protein ac E1A90_23265 ENOG4105BZA Phosphoglycerate kinase E1A90_23270 ENOG4105CP7 Triose-phosphate isomerase E1A90_23280 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) E1A90_23285 ENOG4105DU0 nucleoside hydrolase E1A90_23295 ENOG41067MG lrgb family E1A90_23300 ENOG4105XZU Preprotein translocase, subunit SecG E1A90_23315 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) E1A90_23350 ENOG4105CM4 permease protein E1A90_23355 ENOG4108IPW abc transporter atp-binding protein E1A90_23370 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) E1A90_23375 ENOG4108V2W Carbonate dehydratase E1A90_23395 ENOG4108W2Y isochorismatase E1A90_23400 ENOG4105VPS UPF0291 protein E1A90_23410 ENOG4105KVH Transcriptional regulator E1A90_23415 ENOG4108VY7 phosphate-starvation-inducible protein PsiE E1A90_23420 ENOG4108MK9 spermidine N(1)-acetyltransferase E1A90_23425 ENOG4105C5H ABC transporter E1A90_23445 ENOG4105WMR Protein CrcB homolog E1A90_23450 ENOG4105WMR Protein CrcB homolog E1A90_23460 ENOG4105C8Q Methyl-accepting chemotaxis E1A90_23470 ENOG4105D4A Cell wall formation (By similarity) E1A90_23475 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) E1A90_23490 ENOG4105KVH Transcriptional regulator E1A90_23500 ENOG4105CV8 reductase E1A90_23520 ENOG4108RYK Nad-dependent epimerase dehydratase E1A90_23535 ENOG4105D9N nucleoside E1A90_23545 ENOG41090A1 ferritin E1A90_23555 ENOG4108URH decarboxylase E1A90_23580 ENOG4108RMU ferritin dps family protein E1A90_23590 ENOG4105NCW Trka-c domain protein E1A90_23595 ENOG4107S91 Sodium hydrogen exchanger E1A90_23600 ENOG4107T5V SNARE associated Golgi E1A90_23620 ENOG4105D4Y metalloprotease E1A90_23625 ENOG4105VG1 fes assembly suf system protein E1A90_23635 ENOG4105C8Q Methyl-accepting chemotaxis E1A90_23655 ENOG4105BZU Histidine kinase E1A90_23660 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_23665 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein E1A90_23710 ENOG4107AYK membrAne E1A90_23720 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins E1A90_23735 ENOG4107R7I amino acid E1A90_23740 ENOG4108SUT Major Facilitator Superfamily E1A90_23760 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer E1A90_23780 ENOG4105DZ1 carboxypeptidase E1A90_23795 ENOG4105CHU acetyl-coa acetyltransferase E1A90_23800 ENOG4105C1G acyl-Coa dehydrogenase E1A90_23805 ENOG4108W8B Beta-lactamase domain protein E1A90_23885 ENOG41080E8 Transcriptional regulator, Spx MgsR family E1A90_23890 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) E1A90_23920 ENOG4108UMI ABC transporter, permease E1A90_23925 ENOG4105D01 (LipO)protein E1A90_23930 ENOG4105D01 (LipO)protein E1A90_23935 ENOG4105C3K feS assembly ATPase SufC E1A90_23940 ENOG4105JRK feS assembly protein SufD E1A90_23945 ENOG4105C9B Cysteine desulfurase E1A90_23950 ENOG4108UNV SUF system FeS assembly protein, NifU family E1A90_23955 ENOG4105DIW FeS assembly protein SUFB E1A90_23960 ENOG4107R8B 5'-nucleotidase E1A90_23965 ENOG4105KZD Domain of unknown function (DUF1805) E1A90_23970 ENOG4108YTE sporulation protein YunB E1A90_23980 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) E1A90_24000 ENOG41090T1 Membrane E1A90_24005 ENOG4107TXC Transcriptional regulator E1A90_24010 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) E1A90_24015 ENOG4105MMD transcriptional regulator E1A90_24035 ENOG4105CBT Fructose-1,6-bisphosphatase E1A90_24050 ENOG4105D4U had-superfamily hydrolase, subfamily iia E1A90_24060 ENOG4105DYS nad(p)h dehydrogenase (quinone) E1A90_24065 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) E1A90_24080 ENOG4108W5N phosphatidylglycerophosphatase a E1A90_24095 ENOG41083MR nifu domain-containing protein E1A90_24150 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA E1A90_24155 ENOG4105C4B ABC transporter, permease E1A90_24160 ENOG4108JJA ABC, transporter E1A90_24175 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) E1A90_24180 ENOG4108YX9 iron--sulfur cluster insertion protein erpA E1A90_24205 ENOG4105EWC Purine nucleoside phosphorylase E1A90_24235 ENOG4105CEP NADH dehydrogenase E1A90_24255 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) E1A90_24270 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase E1A90_24285 ENOG4105KA0 thioesterase Superfamily protein E1A90_24290 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) E1A90_24305 ENOG4107R3E Citrate transporter E1A90_24315 ENOG4105Y38 Kinase-associated protein B E1A90_24325 ENOG4105C87 Aminotransferase class I and II E1A90_24340 ENOG4105C5I Dehydrogenase E1A90_24345 ENOG4108ZB6 transcriptional regulator AsnC family E1A90_24350 ENOG4105CHM Aminotransferase E1A90_24360 ENOG4105WG9 Conserved Protein E1A90_24370 ENOG4107S5H glucose-6-phosphate isomerase E1A90_24385 ENOG4105KT7 mgtC SapB transporter E1A90_24525 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) E1A90_24535 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) E1A90_24575 ENOG4105VEQ Cold shock protein E1A90_24590 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase E1A90_24595 ENOG4105E4F Isochorismate synthase E1A90_24605 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) E1A90_24610 ENOG4108IPT Naphthoate synthase E1A90_24615 ENOG4105CEY Amp-dependent synthetase and ligase E1A90_24620 ENOG4105DTQ mandelate racemase muconate lactonizing E1A90_24640 ENOG41069H0 dihydroorotase EC 3.5.2.3 E1A90_24660 ENOG4105FDP GntR family transcriptional regulator E1A90_24665 ENOG4105C6Z Gluconate E1A90_24705 ENOG41082BM Transcriptional regulator, arsr family E1A90_24715 ENOG4105CJ1 ABC, transporter E1A90_24725 ENOG41086D8 Transcriptional regulator E1A90_24730 ENOG4105C19 ABC transporter E1A90_24745 ENOG4107ZTW SNARE associated Golgi E1A90_24785 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) E1A90_24790 ENOG4108UGV hypoxanthine phosphoribosyltransferase E1A90_24815 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E1A90_24820 ENOG4105BZU Histidine kinase E1A90_24890 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii E1A90_24895 ENOG4105C4M (Ubiquinol oxidase) subunit I E1A90_24900 ENOG4108V2W Carbonate dehydratase E1A90_24920 ENOG410839T multidrug resistance protein E1A90_24925 ENOG41080TC multidrug resistance protein E1A90_24970 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) E1A90_24995 ENOG4105D2X ABC transporter substrate-binding protein E1A90_25020 ENOG4107T7U Sulfatase E1A90_25030 ENOG4107S9D Alpha beta hydrolase E1A90_25035 ENOG4105CH6 catalase E1A90_25045 ENOG4105BZU Histidine kinase E1A90_25070 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase E1A90_25075 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP E1A90_25090 ENOG4105EPU Molybdenum cofactor synthesis domain protein E1A90_25105 ENOG4105YVM Phosphoesterase, PA-phosphatase related E1A90_25110 ENOG4108Z0R Transferase E1A90_25115 ENOG4105E8V Alpha Beta Hydrolase Fold protein E1A90_25140 ENOG4105N5T Radical SAM Protein E1A90_25160 ENOG4105C19 ABC transporter E1A90_25180 ENOG4105NCW Trka-c domain protein E1A90_25185 ENOG4107S91 Sodium hydrogen exchanger E1A90_25190 ENOG410605W Major Facilitator E1A90_25225 ENOG4108B31 Spore germination protein E1A90_25235 ENOG4105DWV Homoserine O-trans-acetylase E1A90_25245 ENOG41085GJ domain protein E1A90_25270 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) E1A90_25275 ENOG4105D06 uba thif-type nad fad binding protein E1A90_25285 ENOG4105CVM Molybdenum cofactor synthesis domain protein E1A90_25290 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein E1A90_25295 ENOG4108ZAF Molybdopterin E1A90_25315 ENOG4107EXU Short-chain dehydrogenase reductase Sdr E1A90_25320 ENOG4108VJ1 Transcriptional regulator (CarD family E1A90_25355 ENOG4105CBX hi0933 family E1A90_25370 ENOG4105YW5 deoR family transcriptional regulator E1A90_25375 ENOG4107QSE Dipeptidase E1A90_25385 ENOG4108IUM Glycogen debranching enzyme E1A90_25390 ENOG4108V15 phosphotransferase enzyme family E1A90_25400 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) E1A90_25405 ENOG4105C8F Beta-lactamase domain protein E1A90_25435 ENOG4108VDD TRNA binding domain protein E1A90_25465 ENOG4105DFU Cell wall formation (By similarity) E1A90_25490 ENOG4105C88 aminopeptidase E1A90_25510 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase E1A90_25520 ENOG4105ETE Transcriptional regulator (LacI family E1A90_25540 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) E1A90_25545 ENOG4105EP9 oxidoreductase E1A90_25550 ENOG4107SNB ankyrin repeat protein YahD E1A90_25555 ENOG4105BZU Histidine kinase E1A90_25560 ENOG4105DPZ Two component transcriptional regulator (Winged helix family E1A90_25575 ENOG4105DGU Histone deacetylase E1A90_25585 ENOG4105F1V Acetoin utilization protein E1A90_25595 ENOG4108UW5 maltose o-acetyltransferase E1A90_25605 ENOG4105EMN RNA polymerase sigma factor E1A90_25665 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) E1A90_25675 ENOG4105C28 cystathionine E1A90_25685 ENOG4105U5Y Transcriptional regulator E1A90_25715 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) E1A90_25725 ENOG4105EFZ amidohydrolase E1A90_25740 ENOG4105KBJ sporulation protein ytfj E1A90_25745 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) E1A90_25755 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) E1A90_25775 ENOG4108JYZ YitT family E1A90_25790 ENOG4105CDH Citrulline--aspartate ligase E1A90_25820 ENOG4107YZX Universal stress protein E1A90_25840 ENOG4105VZ8 Transcriptional regulator E1A90_25850 ENOG41082W1 Cupin 2, conserved barrel domain protein E1A90_25895 ENOG4105DC7 peptidase M24 E1A90_25900 ENOG4105E8R UPF0173 metal-dependent hydrolase E1A90_25925 ENOG4105SFS phosphoesterase RecJ domain protein E1A90_25935 ENOG4105VV2 E1A90_25945 ENOG4105C6K Malic enzyme E1A90_25950 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family E1A90_25955 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) E1A90_25965 ENOG4105CTQ phosphohexokinase E1A90_25975 ENOG4105FS0 cytoplasmic membrane protein E1A90_25980 ENOG4108REF Sporulation integral membrane protein ytvi E1A90_25995 ENOG4105BZN citrate synthase E1A90_26000 ENOG4108HMX isocitrate dehydrogenase (NADP) E1A90_26005 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) E1A90_26020 ENOG4105DPZ Two component transcriptional regulator (Winged helix family E1A90_26025 ENOG4105BZU Histidine kinase E1A90_26030 ENOG4105C2M dna polymerase I E1A90_26045 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) E1A90_26050 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase E1A90_26055 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) E1A90_26075 ENOG4108TDW sporulation protein YtxC E1A90_26080 ENOG4105C22 threonyL-tRNA synthetase E1A90_26085 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) E1A90_26095 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) E1A90_26105 ENOG4105CN9 Peptidase m42 family protein E1A90_26110 ENOG4108JGH Tetr family transcriptional regulator E1A90_26115 ENOG4105CW7 secretion protein, HlyD family E1A90_26120 ENOG4105C0R drug resistance transporter emrb qaca subfamily E1A90_26155 ENOG4108RWN rrna methyltransferase E1A90_26160 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) E1A90_26165 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) E1A90_26170 ENOG4105C5S asparaginyl-tRNA synthetase E1A90_26190 ENOG410687F Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) E1A90_26200 ENOG4105DCG PHP domain protein E1A90_26205 ENOG4105C98 muts2 protein E1A90_26210 ENOG4105FE9 pseudouridine synthase E1A90_26220 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) E1A90_26245 ENOG4105E0A ABC, transporter E1A90_26250 ENOG4105KFN sortase, SrtB family E1A90_26255 ENOG4105P9G heme-degrading monooxygenase IsdG E1A90_26265 ENOG4105DR4 Methyltransferase E1A90_26275 ENOG4105DPZ Two component transcriptional regulator (Winged helix family E1A90_26310 ENOG4105S6R Iron-hydroxamate transporter permease subunit E1A90_26315 ENOG4105J76 Periplasmic binding protein E1A90_26330 ENOG4107Z3H Transcriptional regulator, TetR family E1A90_26335 ENOG41060WC Enoyl-CoA hydratase E1A90_26340 ENOG4105BZJ Electron transfer flavoprotein E1A90_26345 ENOG4105C10 Electron transfer flavoprotein E1A90_26350 ENOG4105K63 Thioredoxin E1A90_26365 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit E1A90_26375 ENOG4105E33 succinate dehydrogenase E1A90_26385 ENOG4108VXD carboxy-peptidase E1A90_26395 ENOG4105E14 MotA TolQ exbB proton channel E1A90_26405 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family E1A90_26410 ENOG4108IUX (ABC) transporter E1A90_26415 ENOG4105RHA ABC transporter, permease E1A90_26420 ENOG4108Z40 Transcriptional regulator E1A90_26425 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) E1A90_26435 ENOG4108JCI Transcriptional regulator E1A90_26440 ENOG41067S9 phage shock protein C, PspC E1A90_26445 ENOG4105DZC cytosine deaminase E1A90_26455 ENOG4105PFC Transcriptional regulator E1A90_26465 ENOG4105KBX Transcriptional regulator, TetR family E1A90_26475 ENOG4105C57 major facilitator superfamily E1A90_26485 ENOG4108XJQ germination protein E1A90_26490 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) E1A90_26500 ENOG4105M59 Phosphodiesterase, mj0936 family E1A90_26515 ENOG4108QCI YvbH-like oligomerisation region E1A90_26530 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation E1A90_26540 ENOG4108IUQ atp-dependent protease E1A90_26550 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) E1A90_26560 ENOG4105K56 Transcriptional regulator E1A90_26565 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) E1A90_26575 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) E1A90_26585 ENOG4105D52 delta-aminolevulinic acid dehydratase E1A90_26590 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase E1A90_26595 ENOG41068KH stage VI sporulation protein D E1A90_26605 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) E1A90_26610 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase E1A90_26625 ENOG4108Z03 MAF-like protein E1A90_26630 ENOG4105W5Q DNA repair protein (RadC E1A90_26640 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) E1A90_26650 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) E1A90_26655 ENOG4107QMS site-determining protein E1A90_26680 ENOG4105X36 (ribosomal) protein E1A90_26695 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control E1A90_26705 ENOG4105EWM Histidine kinase E1A90_26725 ENOG4105CQC Prephenate dehydratase E1A90_26730 ENOG4108RPX mosc domain containing protein E1A90_26750 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase E1A90_26755 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) E1A90_26785 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) E1A90_26790 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) E1A90_26795 ENOG41061AI Protein of unknown function (DUF2905) E1A90_26800 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) E1A90_26805 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) E1A90_26825 ENOG4105CKP Polysaccharide Biosynthesis Protein E1A90_26835 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) E1A90_26845 ENOG41076HS cation diffusion facilitator family transporter E1A90_26850 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) E1A90_26855 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) E1A90_26860 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) E1A90_26865 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) E1A90_26870 ENOG4105CUT histidyl-tRNA synthetase E1A90_26880 ENOG4105CUZ uba thif-type nad fad binding protein E1A90_26885 ENOG4108VCI transcription factor, rsfa family E1A90_26890 ENOG4105D1H recombination factor protein RarA E1A90_26900 ENOG4105C3J Cysteine desulfurase E1A90_26905 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) E1A90_26920 ENOG41060CR E1A90_26935 ENOG4105C02 permease E1A90_26945 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) E1A90_26955 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) E1A90_26965 ENOG4105HHA aminodeoxychorismate lyase E1A90_26970 ENOG4108VQJ O-methyltransferase E1A90_26975 ENOG4105XYU peptidase (U32 family) E1A90_26980 ENOG4105CFP Peptidase U32 E1A90_26985 ENOG4105DBI uridine monophosphokinase E1A90_26995 ENOG4107XRG penicillin-binding protein E1A90_27015 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) E1A90_27025 ENOG4105C28 cystathionine E1A90_27050 ENOG4108EKI Dehydrogenase E1A90_27060 ENOG4108V5C ABC transporter E1A90_27065 ENOG4105S6R Iron-hydroxamate transporter permease subunit E1A90_27105 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase E1A90_27115 ENOG4105MIR Phenylalanine 4-monooxygenase E1A90_27120 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin E1A90_27155 ENOG4108MUZ hydrolase E1A90_27165 ENOG4105G6Z alkaline phosphatase E1A90_27190 ENOG4105DJ4 phosphatidylserine decarboxylase E1A90_27200 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase E1A90_27205 ENOG4105CQW ribosome biogenesis GTPase YqeH E1A90_27210 ENOG4105E2X shikimate dehydrogenase E1A90_27215 ENOG410812S Rna-binding protein E1A90_27220 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) E1A90_27225 ENOG4108WF2 Metal Dependent Phosphohydrolase E1A90_27250 ENOG4108UK2 deaminase E1A90_27255 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 E1A90_27270 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) E1A90_27275 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) E1A90_27285 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) E1A90_27290 ENOG4105KVH Transcriptional regulator E1A90_27295 ENOG4105CSA Coproporphyrinogen iii oxidase E1A90_27325 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) E1A90_27345 ENOG4105KTH gatB Yqey E1A90_27350 ENOG41068P3 sporulation protein YqfC E1A90_27360 ENOG4105C9A Phoh family E1A90_27370 ENOG4107YVF Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) E1A90_27375 ENOG4107YR5 Diacylglycerol kinase E1A90_27380 ENOG4105KG3 cytidine deaminase E1A90_27385 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) E1A90_27395 ENOG4108SAY Involved in DNA repair and RecF pathway recombination (By similarity) E1A90_27415 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) E1A90_27420 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E1A90_27435 ENOG4105EGD dinuclear metal center protein, YbgI family E1A90_27460 ENOG41069ZM Protein of unknown function (DUF2624) E1A90_27465 ENOG4108JYZ YitT family E1A90_27480 ENOG4105N80 Ferric uptake regulator, Fur family E1A90_27485 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) E1A90_27505 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) E1A90_27520 ENOG4105PWN phosphate abc transporter E1A90_27525 ENOG4105C8U phosphate abc transporter E1A90_27530 ENOG4105E2Z phosphate ABC transporter (Permease E1A90_27535 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) E1A90_27540 ENOG4108UTW Plays a role in the regulation of phosphate uptake E1A90_27555 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase E1A90_27565 ENOG4105DKQ ROK family E1A90_27575 ENOG4105C5X domain protein E1A90_27595 ENOG4105C28 cystathionine E1A90_27600 ENOG4105C28 cystathionine E1A90_27610 ENOG4105C3R Methionine synthase E1A90_27705 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) E1A90_27735 ENOG4105C0D helicase E1A90_27740 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) E1A90_27745 ENOG4107QK8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor E1A90_27750 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor E1A90_27765 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family E1A90_27800 ENOG41080TC multidrug resistance protein E1A90_27830 ENOG41082GG biotin lipoate A B protein ligase E1A90_27860 ENOG4107YBY Hydrolase E1A90_27870 ENOG4105CBJ Metal-dependent enzyme E1A90_27880 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) E1A90_27885 ENOG4105DC7 peptidase M24 E1A90_27890 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) E1A90_27910 ENOG4105CD2 stage iii sporulation protein aa E1A90_27915 ENOG4105KR5 Stage iii sporulation protein E1A90_27920 ENOG4108CQH stage III sporulation protein AC E1A90_27925 ENOG4105KQ4 Stage iii sporulation protein ad E1A90_27935 ENOG410644B Stage III sporulation protein af E1A90_27960 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase E1A90_27965 ENOG4108ZSR alkaline shock protein E1A90_27970 ENOG4105M7K Involved in the transcription termination process (By similarity) E1A90_27975 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) E1A90_27980 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) E1A90_27985 ENOG41082UU Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) E1A90_28000 ENOG4105DX0 Hemolysin A E1A90_28010 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) E1A90_28015 ENOG4105S1Z Stage IV sporulation protein B E1A90_28025 ENOG4107QQR Sporulation E1A90_28065 ENOG4108QXE glycerophosphoryl diester phosphodiesterase E1A90_28070 ENOG4106CCJ Protein of unknown function (DUF2627) E1A90_28090 ENOG4107RDP Dehydrogenase E1A90_28110 ENOG4105CPP Dehydrogenase, E1 component E1A90_28115 ENOG4105C7S Dehydrogenase E1A90_28130 ENOG4108QY0 Membrane E1A90_28135 ENOG4105E09 nadh pyrophosphatase E1A90_28140 ENOG4105G7B Protein of unknown function (DUF2992) E1A90_28150 ENOG4108HW3 (ABC) transporter E1A90_28155 ENOG4105E5Q amino acid AbC transporter E1A90_28165 ENOG4108QEG Membrane E1A90_28170 ENOG4108VZI ErfK ybiS ycfS ynhG family protein E1A90_28180 ENOG4105D9U N-acetyltransferase E1A90_28185 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) E1A90_28200 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic E1A90_28210 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) E1A90_28225 ENOG4105EJQ L-serine dehydratase E1A90_28235 ENOG41069FQ Metallo-beta-lactamase superfamily E1A90_28240 ENOG4108IXY short-chain dehydrogenase reductase E1A90_28250 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase E1A90_28260 ENOG4105CAS nag kinase E1A90_28295 ENOG4105CGH 5'-nucleotidase E1A90_28315 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) E1A90_28325 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) E1A90_28330 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) E1A90_28335 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) E1A90_28355 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) E1A90_28360 ENOG4108R6K riboflavin synthase, subunit alpha E1A90_28365 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) E1A90_28385 ENOG4108YM7 Gcn5-related n-acetyltransferase E1A90_28395 ENOG4105ETE Transcriptional regulator (LacI family E1A90_28405 ENOG4107SKW Inherit from COG: Alpha beta hydrolase E1A90_28430 ENOG4105RHY Pfam:UPF0157 E1A90_28440 ENOG4105CPC Aldo Keto reductase E1A90_28460 ENOG4105MZ9 stage II sporulation protein m E1A90_28465 ENOG4105I3K Ferric uptake regulator, Fur family E1A90_28475 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) E1A90_28485 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) E1A90_28500 ENOG4105D7N magnesium and cobalt transport protein CorA E1A90_28540 ENOG4105DVE abc transporter atp-binding protein E1A90_28545 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family E1A90_28550 ENOG4105DZ1 carboxypeptidase E1A90_28555 ENOG41082AN stage II sporulation protein E1A90_28565 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E1A90_28585 ENOG41090VF Stage v sporulation protein ac E1A90_28590 ENOG4105CZ3 stage V sporulation protein ad E1A90_28610 ENOG4105J7I hydrolase E1A90_28615 ENOG4105PTM secreted protein E1A90_28620 ENOG4107ZE5 PPIases accelerate the folding of proteins E1A90_28640 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) E1A90_28650 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) E1A90_28660 ENOG4105CE4 GlcNAc 6-P deacetylase E1A90_28670 ENOG4105FDP GntR family transcriptional regulator E1A90_28680 ENOG4105CID antiterminator E1A90_28695 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) E1A90_28725 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase E1A90_28740 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) E1A90_28785 ENOG4105DTD Dehydrogenase E1A90_28790 ENOG4105K7K Transcriptional regulator E1A90_28825 ENOG4105CHU acetyl-coa acetyltransferase E1A90_28870 ENOG4105CG3 alpha amylase, catalytic region E1A90_28880 ENOG4107FKK extracellular solute-binding protein family 1 E1A90_28890 ENOG4105EG2 ABC transporter, permease E1A90_28895 ENOG4105FKQ transcriptional regulator E1A90_28900 ENOG4105CHM Aminotransferase E1A90_28930 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) E1A90_28975 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) E1A90_28990 ENOG4105K6S Short-chain dehydrogenase reductase Sdr E1A90_28995 ENOG4105EPM Diguanylate phosphodiesterase E1A90_29010 ENOG4107IN1 Protein of unknown function (DUF1797) E1A90_29020 ENOG4108XRC Protein of unknown function (DUF458) E1A90_29040 ENOG4105DMJ Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity) E1A90_29055 ENOG4107ZYR domain protein E1A90_29060 ENOG4105CN5 Metallo-Beta-Lactamase E1A90_29075 ENOG4108X4Q Hydrolase E1A90_29080 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) E1A90_29095 ENOG4105CPP Dehydrogenase, E1 component E1A90_29100 ENOG4105C7S Dehydrogenase E1A90_29145 ENOG4105CXN decarboxylase E1A90_29155 ENOG4108WQ8 UPF0637 protein E1A90_29165 ENOG4105ECY inositol monophosphatase E1A90_29175 ENOG4105CI3 gtp-binding protein typa E1A90_29200 ENOG4108IAB Phoh family E1A90_29210 ENOG4105ZPI UPF0358 protein E1A90_29270 ENOG4106UY4 Inherit from COG: Scp-like extracellular E1A90_29285 ENOG4107TB6 phosphoglycerate mutase E1A90_29295 ENOG4105WUC UPF0298 protein E1A90_29310 ENOG4106H78 methyltransferase E1A90_29315 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) E1A90_29320 ENOG4105H20 Sporulation integral membrane protein YlbJ E1A90_29325 ENOG4105D78 K07001 NTE family protein E1A90_29330 ENOG41063PX domain protein E1A90_29340 ENOG4105KNH Nucleic acid-binding protein E1A90_29365 ENOG41074B2 UPF0747 protein E1A90_29370 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) E1A90_29385 ENOG4105CJN penicillin-binding protein E1A90_29390 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) E1A90_29395 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) E1A90_29400 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) E1A90_29405 ENOG4105CNI cell division protein FtsW E1A90_29410 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) E1A90_29420 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) E1A90_29425 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) E1A90_29430 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) E1A90_29440 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E1A90_29450 ENOG4105WR5 sporulation protein, YlmC YmxH family E1A90_29455 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase E1A90_29460 ENOG4105DFA alanine racemase domain protein E1A90_29465 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) E1A90_29470 ENOG41067XK integral membrane protein E1A90_29475 ENOG4105DBK s4 domain protein E1A90_29485 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) E1A90_29500 ENOG4105C34 Pseudouridine synthase E1A90_29505 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) E1A90_29515 ENOG4105CXT aspartate transcarbamylase E1A90_29520 ENOG4105CD3 dihydroorotase E1A90_29535 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) E1A90_29590 ENOG4105F23 Fibronectin-binding protein E1A90_29600 ENOG4105DSJ YicC domain protein E1A90_29620 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase E1A90_29625 ENOG4105C25 Primosomal protein n' E1A90_29630 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) E1A90_29635 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) E1A90_29640 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B E1A90_29645 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs E1A90_29650 ENOG4108ZF3 Phosphatase E1A90_29655 ENOG4105D9P serine threonine protein kinase E1A90_29665 ENOG4105DJV ribulose-phosphate 3-epimerase E1A90_29685 ENOG4108ZAA Alkaline-shock protein E1A90_29700 ENOG4105CB5 ATP-dependent DNA helicase recG E1A90_29710 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) E1A90_29715 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase E1A90_29720 ENOG4105CHR reductase E1A90_29725 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) E1A90_29735 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) E1A90_29740 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) E1A90_29745 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) E1A90_29760 ENOG4105VB6 UPF0109 protein E1A90_29765 ENOG4107Z8R An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) E1A90_29770 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) E1A90_29785 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) E1A90_29790 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) E1A90_29800 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha E1A90_29805 ENOG4105C79 DNA protecting protein DprA E1A90_29810 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) E1A90_29820 ENOG4108HE4 integrase family E1A90_29840 ENOG4105CE9 30S ribosomal protein S2 E1A90_29845 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) E1A90_29855 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) E1A90_29860 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) E1A90_29865 ENOG4105KNE Phosphatidate cytidylyltransferase E1A90_29875 ENOG4105DZP Membrane-associated zinc metalloprotease E1A90_29880 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) E1A90_29895 ENOG4105CHV Transcription elongation factor NusA E1A90_29905 ENOG4105VHM ribosomal protein E1A90_29915 ENOG4105W7A Protein of unknown function (DUF503) E1A90_29940 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) E1A90_29950 ENOG4105C1V Peptidase, M16 E1A90_29960 ENOG4105E35 Dipicolinate synthase subunit A E1A90_29965 ENOG4108S0H Dipicolinic acid synthetase, b subunit E1A90_29970 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) E1A90_29980 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) E1A90_29990 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit E1A90_30005 ENOG4105FDP GntR family transcriptional regulator E1A90_30010 ENOG4105DIH basic membrane E1A90_30015 ENOG4108JQ9 ABC transporter E1A90_30020 ENOG4105UIB (ABC) transporter E1A90_30040 ENOG4108RKS Short-chain dehydrogenase reductase Sdr E1A90_30045 ENOG4105XZV Protein of unknown function (DUF3243) E1A90_30060 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase E1A90_30065 ENOG4105CEV competence damage-inducible protein E1A90_30075 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) E1A90_30080 ENOG4105D48 metallophosphoesterase E1A90_30085 ENOG4105MCT stage V sporulation protein S E1A90_30095 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein E1A90_30100 ENOG4105DQU oxidoreductase, subunit beta E1A90_30105 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) E1A90_30120 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) E1A90_30140 ENOG410890F Dynamin family E1A90_30155 ENOG4105F0V Cell wall hydrolase E1A90_30165 ENOG4105CS2 ec 3.2.1.21 E1A90_30170 ENOG4108S3Y transcriptional regulator E1A90_30185 ENOG4107YEI lmbE family E1A90_30190 ENOG4108VQT Alpha beta hydrolase fold protein E1A90_30205 ENOG41067MG lrgb family