locus-tag	class	description
GSN03_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GSN03_00010	COG0592	DNA-directed DNA polymerase activity
GSN03_00015	COG2501	S4 domain
GSN03_00025	COG0187	DNA topoisomerase II activity
GSN03_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GSN03_00065	COG0517	IMP dehydrogenase activity
GSN03_00065	COG0516	GMP reductase activity
GSN03_00070	COG1686	Belongs to the peptidase S11 family
GSN03_00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GSN03_00100	COG1428	Deoxynucleoside kinase
GSN03_00105	COG1428	Deoxynucleoside kinase
GSN03_00110	COG1335	isochorismatase
GSN03_00115	COG0590	tRNA wobble adenosine to inosine editing
GSN03_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GSN03_00180	COG1982	Orn Lys Arg decarboxylase major
GSN03_00190	COG0470	DNA polymerase III
GSN03_00195	COG1774	PSP1 C-terminal conserved region
GSN03_00200	COG4467	Involved in initiation control of chromosome replication
GSN03_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GSN03_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GSN03_00220	COG2002	toxin-antitoxin pair type II binding
GSN03_00230	COG0084	hydrolase, TatD family'
GSN03_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GSN03_00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GSN03_00250	COG4466	Protein conserved in bacteria
GSN03_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GSN03_00270	COG0251	oxidation-reduction process
GSN03_00275	COG2088	sporulation resulting in formation of a cellular spore
GSN03_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GSN03_00305	COG2002	toxin-antitoxin pair type II binding
GSN03_00310	COG2244	polysaccharide biosynthetic process
GSN03_00315	COG3956	TIGRFAM MazG family protein
GSN03_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GSN03_00340	COG1098	S1 RNA binding domain
GSN03_00355	COG2208	phosphoserine phosphatase activity
GSN03_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GSN03_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GSN03_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GSN03_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GSN03_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
GSN03_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GSN03_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GSN03_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GSN03_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GSN03_00420	COG1396	sequence-specific DNA binding
GSN03_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GSN03_00455	COG3880	PFAM UvrB UvrC protein
GSN03_00460	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GSN03_00465	COG0542	response to heat
GSN03_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GSN03_00475	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GSN03_00480	COG4956	integral membrane protein (PIN domain superfamily)
GSN03_00485	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GSN03_00495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GSN03_00500	COG1045	serine acetyltransferase
GSN03_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GSN03_00520	COG3688	RNA-binding protein containing a PIN domain
GSN03_00530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GSN03_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GSN03_00540	COG0250	Participates in transcription elongation, termination and antitermination
GSN03_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GSN03_00550	COG0081	regulation of translation
GSN03_00555	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GSN03_00560	COG0222	ribosome binding
GSN03_00565	COG2813	Specifically methylates the guanine in position
GSN03_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GSN03_00580	COG1358	cellular component organization or biogenesis
GSN03_00585	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GSN03_00595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GSN03_00605	COG0051	transcription antitermination factor activity, RNA binding
GSN03_00610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GSN03_00615	COG0088	Forms part of the polypeptide exit tunnel
GSN03_00620	COG0089	rRNA binding
GSN03_00625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GSN03_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
GSN03_00670	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GSN03_00700	COG1841	ribosomal large subunit assembly
GSN03_00710	COG0201	protein transport
GSN03_00720	COG0024	Methionine aminopeptidase
GSN03_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GSN03_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GSN03_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
GSN03_00795	COG0489	protein tyrosine kinase activity
GSN03_00805	COG2194	sulfuric ester hydrolase activity
GSN03_00810	COG0726	polysaccharide deacetylase
GSN03_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GSN03_00895	COG4856	YbbR-like protein
GSN03_00915	COG4946	Tricorn protease homolog
GSN03_00915	COG1506	peptidase
GSN03_00915	COG0823	Involved in the tonB-independent uptake of proteins
GSN03_00930	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_00935	COG2011	ABC-type metal ion transport system permease component
GSN03_00945	COG1464	Belongs to the NlpA lipoprotein family
GSN03_00950	COG0604	alcohol dehydrogenase
GSN03_00960	COG0277	FAD linked oxidase domain protein
GSN03_00965	COG2271	Major facilitator Superfamily
GSN03_00975	COG2814	Major facilitator Superfamily
GSN03_00990	COG0601	transmembrane transport
GSN03_00995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSN03_01000	COG0444	Belongs to the ABC transporter superfamily
GSN03_01005	COG4608	Belongs to the ABC transporter superfamily
GSN03_01010	COG4166	transmembrane transport
GSN03_01020	COG4166	transmembrane transport
GSN03_01025	COG4166	transmembrane transport
GSN03_01030	COG0656	L-ascorbic acid biosynthetic process
GSN03_01050	COG4149	molybdate abc transporter
GSN03_01055	COG0725	ABC transporter, periplasmic molybdate-binding protein
GSN03_01060	COG1910	domain protein
GSN03_01075	COG0697	spore germination
GSN03_01090	COG0204	Acyl-transferase
GSN03_01100	COG1609	Transcriptional regulator
GSN03_01110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSN03_01130	COG5298	Protein conserved in bacteria
GSN03_01150	COG0488	(ABC) transporter
GSN03_01160	COG0747	negative chemotaxis
GSN03_01165	COG0747	negative chemotaxis
GSN03_01170	COG0601	transmembrane transport
GSN03_01175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSN03_01180	COG0444	Belongs to the ABC transporter superfamily
GSN03_01185	COG4608	Belongs to the ABC transporter superfamily
GSN03_01190	COG0561	phosphatase activity
GSN03_01220	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GSN03_01225	COG0179	Fumarylacetoacetate (FAA) hydrolase
GSN03_01235	COG0531	amino acid
GSN03_01240	COG2814	Major facilitator Superfamily
GSN03_01250	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GSN03_01260	COG4294	response to UV
GSN03_01265	COG0705	Rhomboid family
GSN03_01275	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GSN03_01280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GSN03_01285	COG0864	Transcriptional regulator
GSN03_01290	COG2337	Toxic component of a toxin-antitoxin (TA) module
GSN03_01295	COG2183	response to ionizing radiation
GSN03_01395	COG0802	atpase or kinase
GSN03_01400	COG1214	PFAM Peptidase M22, glycoprotease
GSN03_01405	COG0456	acetyltransferase
GSN03_01415	COG0488	(ABC) transporter
GSN03_01420	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GSN03_01430	COG1266	CAAX protease self-immunity
GSN03_01440	COG0459	protein refolding
GSN03_01445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GSN03_01445	COG0519	Catalyzes the synthesis of GMP from XMP
GSN03_01450	COG2252	PERMEase
GSN03_01460	COG5002	protein histidine kinase activity
GSN03_01485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GSN03_01505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSN03_01510	COG0506	proline dehydrogenase activity
GSN03_01550	COG2205	protein histidine kinase activity
GSN03_01555	COG0745	RESPONSE REGULATOR receiver
GSN03_01575	COG0697	spore germination
GSN03_01600	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GSN03_01605	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GSN03_01610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GSN03_01620	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GSN03_01625	COG0047	phosphoribosylformylglycinamidine synthase activity
GSN03_01635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GSN03_01645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GSN03_01655	COG0151	Belongs to the GarS family
GSN03_01675	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GSN03_01680	COG0210	DNA helicase
GSN03_01685	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GSN03_01690	COG4851	CamS sex pheromone cAM373 precursor
GSN03_01700	COG1012	belongs to the aldehyde dehydrogenase family
GSN03_01705	COG1335	isochorismatase
GSN03_01715	COG2011	ABC-type metal ion transport system permease component
GSN03_01720	COG1464	Belongs to the NlpA lipoprotein family
GSN03_01735	COG0003	Pfam Anion-transporting ATPase
GSN03_01740	COG1846	Transcriptional regulator
GSN03_01745	COG4682	membrane
GSN03_01755	COG0154	amidase activity
GSN03_01765	COG1597	lipid kinase activity
GSN03_01775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GSN03_01785	COG1012	belongs to the aldehyde dehydrogenase family
GSN03_01790	COG2076	Multidrug Resistance protein
GSN03_01795	COG2309	aminopeptidase activity
GSN03_01810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GSN03_01820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GSN03_01825	COG5002	protein histidine kinase activity
GSN03_01830	COG4807	Protein conserved in bacteria
GSN03_01860	COG1757	Na H antiporter
GSN03_01865	COG1473	amidohydrolase
GSN03_01880	COG0450	alkyl hydroperoxide reductase
GSN03_01890	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GSN03_01900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSN03_01905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSN03_01910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GSN03_01915	COG0492	ferredoxin-NADP+ reductase activity
GSN03_01925	COG0166	Belongs to the GPI family
GSN03_01950	COG5002	protein histidine kinase activity
GSN03_01970	COG3541	Predicted nucleotidyltransferase
GSN03_01975	COG0723	plastoquinol--plastocyanin reductase activity
GSN03_01975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSN03_01985	COG0765	amino acid transport
GSN03_01990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSN03_02000	COG0840	transmembrane signaling receptor activity
GSN03_02025	COG0549	Belongs to the carbamate kinase family
GSN03_02040	COG0277	FAD linked oxidase domain protein
GSN03_02045	COG0366	Alpha amylase catalytic
GSN03_02050	COG1263	PTS System
GSN03_02050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GSN03_02050	COG2190	(PTS) system
GSN03_02070	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GSN03_02080	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GSN03_02095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSN03_02100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSN03_02105	COG1116	anion transmembrane transporter activity
GSN03_02115	COG0488	(ABC) transporter
GSN03_02160	COG2270	Major facilitator Superfamily
GSN03_02190	COG2310	stress, protein
GSN03_02195	COG2310	stress, protein
GSN03_02200	COG2310	stress, protein
GSN03_02205	COG0861	Integral membrane protein TerC family
GSN03_02215	COG3853	Toxic anion resistance protein (TelA)
GSN03_02230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GSN03_02240	COG1295	ribonuclease BN
GSN03_02245	COG2217	Heavy metal translocating P-type atpase
GSN03_02250	COG0697	spore germination
GSN03_02270	COG0586	Pfam SNARE associated Golgi protein
GSN03_02285	COG3871	stress protein (general stress protein 26)
GSN03_02290	COG0387	Pfam Sodium calcium exchanger
GSN03_02300	COG0535	radical SAM domain protein
GSN03_02320	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GSN03_02325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GSN03_02330	COG0582	viral genome integration into host DNA
GSN03_02375	COG1484	DNA-dependent DNA replication
GSN03_02385	COG2002	toxin-antitoxin pair type II binding
GSN03_02440	COG0582	viral genome integration into host DNA
GSN03_02485	COG1802	Transcriptional regulator
GSN03_02485	COG4626	Terminase
GSN03_02495	COG0740	serine-type endopeptidase activity
GSN03_02600	COG3829	transcription factor binding
GSN03_02610	COG0833	amino acid
GSN03_02615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GSN03_02640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GSN03_02640	COG1263	PTS System
GSN03_02645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GSN03_02660	COG0463	Glycosyl transferase, family 2
GSN03_02670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GSN03_02670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSN03_02675	COG0463	Glycosyl transferase, family 2
GSN03_02685	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GSN03_02690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GSN03_02705	COG1228	amidohydrolase
GSN03_02710	COG1090	epimerase
GSN03_02740	COG1988	membrane-bound metal-dependent
GSN03_02745	COG1194	a g-specific adenine glycosylase
GSN03_02760	COG3557	Belongs to the UPF0374 family
GSN03_02765	COG1132	(ABC) transporter
GSN03_02770	COG4129	membrane
GSN03_02775	COG0070	glutamate synthase
GSN03_02775	COG0069	glutamate synthase activity
GSN03_02775	COG0067	glutamate synthase
GSN03_02780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GSN03_02785	COG4555	ABC transporter
GSN03_02805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GSN03_02810	COG0735	belongs to the Fur family
GSN03_02925	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GSN03_02930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GSN03_02950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GSN03_02955	COG5001	Diguanylate cyclase
GSN03_02955	COG1716	ATPase activity
GSN03_02960	COG2766	serine protein kinase
GSN03_02985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GSN03_03045	COG0583	DNA-binding transcription factor activity
GSN03_03050	COG0589	response to stress
GSN03_03075	COG1585	Membrane protein implicated in regulation of membrane protease activity
GSN03_03080	COG2268	Band 7 protein
GSN03_03085	COG3290	protein histidine kinase activity
GSN03_03090	COG4565	transcriptional regulatory protein
GSN03_03095	COG2851	Citrate transporter
GSN03_03120	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GSN03_03125	COG3842	ATPase activity
GSN03_03130	COG1175	transmembrane transport
GSN03_03135	COG0395	ABC-type sugar transport system, permease component
GSN03_03145	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GSN03_03150	COG0745	RESPONSE REGULATOR receiver
GSN03_03155	COG5002	protein histidine kinase activity
GSN03_03165	COG4990	cell redox homeostasis
GSN03_03175	COG3290	protein histidine kinase activity
GSN03_03180	COG4565	transcriptional regulatory protein
GSN03_03185	COG3493	citrate carrier protein
GSN03_03190	COG0281	malic enzyme
GSN03_03200	COG0697	spore germination
GSN03_03205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSN03_03215	COG5002	protein histidine kinase activity
GSN03_03220	COG0745	RESPONSE REGULATOR receiver
GSN03_03225	COG0456	acetyltransferase
GSN03_03230	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GSN03_03235	COG3383	formate dehydrogenase (NAD+) activity
GSN03_03240	COG2427	Protein of unknown function (DUF1641)
GSN03_03255	COG0531	amino acid
GSN03_03265	COG0640	Transcriptional regulator
GSN03_03270	COG2217	Heavy metal translocating P-type atpase
GSN03_03275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GSN03_03290	COG3227	Zinc metalloprotease (Elastase)
GSN03_03310	COG2720	vancomycin resistance protein
GSN03_03315	COG1316	TRANSCRIPTIONal
GSN03_03320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GSN03_03325	COG0346	lactoylglutathione lyase activity
GSN03_03330	COG1253	flavin adenine dinucleotide binding
GSN03_03335	COG1027	Aspartate ammonia-lyase
GSN03_03340	COG1620	l-lactate permease
GSN03_03345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GSN03_03360	COG3104	oligopeptide transport
GSN03_03365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GSN03_03370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSN03_03375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSN03_03390	COG0156	8-amino-7-oxononanoate synthase activity
GSN03_03395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSN03_03405	COG4548	von Willebrand factor, type A
GSN03_03410	COG0714	Associated with various cellular activities
GSN03_03430	COG0531	amino acid
GSN03_03435	COG2188	Transcriptional regulator
GSN03_03440	COG1263	PTS System
GSN03_03440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GSN03_03445	COG0366	Alpha amylase catalytic
GSN03_03460	COG0697	spore germination
GSN03_03465	COG4585	Histidine kinase
GSN03_03470	COG2197	response regulator
GSN03_03475	COG1404	Belongs to the peptidase S8 family
GSN03_03490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GSN03_03495	COG1115	amino acid carrier protein
GSN03_03500	COG1126	abc transporter atp-binding protein
GSN03_03505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSN03_03510	COG0765	amino acid transport
GSN03_03515	COG0765	amino acid transport
GSN03_03520	COG0833	amino acid
GSN03_03530	COG2378	regulation of single-species biofilm formation
GSN03_03535	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GSN03_03540	COG5002	protein histidine kinase activity
GSN03_03555	COG0659	secondary active sulfate transmembrane transporter activity
GSN03_03570	COG0747	negative chemotaxis
GSN03_03580	COG0601	transmembrane transport
GSN03_03585	COG4608	Belongs to the ABC transporter superfamily
GSN03_03595	COG2271	Major facilitator Superfamily
GSN03_03600	COG1846	Transcriptional regulator
GSN03_03605	COG0477	Major facilitator Superfamily
GSN03_03610	COG1609	Transcriptional regulator
GSN03_03615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSN03_03620	COG1869	D-ribose catabolic process
GSN03_03630	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSN03_03635	COG1879	ABC-type sugar transport system periplasmic component
GSN03_03665	COG1063	alcohol dehydrogenase
GSN03_03710	COG0840	transmembrane signaling receptor activity
GSN03_03715	COG1388	LysM domain
GSN03_03715	COG3584	3D domain protein
GSN03_03720	COG1476	TRANSCRIPTIONal
GSN03_03740	COG3104	oligopeptide transport
GSN03_03745	COG1114	Component of the transport system for branched-chain amino acids
GSN03_03750	COG1464	Belongs to the NlpA lipoprotein family
GSN03_03755	COG1960	acyl-CoA dehydrogenase activity
GSN03_03760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GSN03_03765	COG2011	ABC-type metal ion transport system permease component
GSN03_03780	COG1113	amino acid transport
GSN03_03785	COG2252	PERMEase
GSN03_03810	COG0475	glutathione-regulated potassium exporter activity
GSN03_03810	COG0569	domain protein
GSN03_03820	COG1845	cytochrome c oxidase, subunit III
GSN03_03825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GSN03_03830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GSN03_03835	COG0833	amino acid
GSN03_03840	COG4990	cell redox homeostasis
GSN03_03855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GSN03_03860	COG0697	spore germination
GSN03_03865	COG0531	amino acid
GSN03_03875	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GSN03_03880	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GSN03_03885	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GSN03_03885	COG1918	ferrous iron import across plasma membrane
GSN03_03890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GSN03_03895	COG0573	inorganic phosphate transmembrane transporter activity
GSN03_03900	COG0581	inorganic phosphate transmembrane transporter activity
GSN03_03910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GSN03_04030	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GSN03_04045	COG0860	N-Acetylmuramoyl-L-alanine amidase
GSN03_04045	COG3103	Sh3 type 3 domain protein
GSN03_04045	COG4991	sh3 domain protein
GSN03_04050	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GSN03_04055	COG1116	anion transmembrane transporter activity
GSN03_04060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSN03_04065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSN03_04070	COG0352	thiamine-phosphate diphosphorylase activity
GSN03_04075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSN03_04080	COG2104	thiamine diphosphate biosynthetic process
GSN03_04085	COG2022	thiamine diphosphate biosynthetic process
GSN03_04090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GSN03_04095	COG0351	phosphomethylpyrimidine kinase
GSN03_04125	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GSN03_04130	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GSN03_04135	COG2205	protein histidine kinase activity
GSN03_04160	COG1131	(ABC) transporter
GSN03_04185	COG1136	(ABC) transporter
GSN03_04200	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSN03_04205	COG1129	ABC transporter
GSN03_04210	COG1879	ABC-type sugar transport system periplasmic component
GSN03_04215	COG2252	PERMEase
GSN03_04220	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_04280	COG0778	Nitroreductase
GSN03_04285	COG2719	SpoVR family
GSN03_04305	COG0446	pyridine nucleotide-disulphide oxidoreductase
GSN03_04310	COG1937	Protein conserved in bacteria
GSN03_04315	COG0425	Belongs to the sulfur carrier protein TusA family
GSN03_04315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GSN03_04320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSN03_04320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GSN03_04325	COG0425	Belongs to the sulfur carrier protein TusA family
GSN03_04330	COG0425	Belongs to the sulfur carrier protein TusA family
GSN03_04330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GSN03_04335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GSN03_04340	COG2210	Belongs to the sulfur carrier protein TusA family
GSN03_04345	COG0730	response to heat
GSN03_04355	COG1316	TRANSCRIPTIONal
GSN03_04360	COG0604	alcohol dehydrogenase
GSN03_04365	COG1283	sodium-dependent phosphate transmembrane transporter activity
GSN03_04370	COG2814	Major facilitator Superfamily
GSN03_04380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GSN03_04380	COG3711	transcriptional antiterminator
GSN03_04385	COG1447	Phosphotransferase system cellobiose-specific component IIA
GSN03_04390	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GSN03_04415	COG3584	3D domain protein
GSN03_04415	COG1388	LysM domain
GSN03_04420	COG0577	efflux transmembrane transporter activity
GSN03_04425	COG1136	(ABC) transporter
GSN03_04435	COG5522	Integral membrane protein (intg_mem_TP0381)
GSN03_04450	COG0577	efflux transmembrane transporter activity
GSN03_04455	COG1114	Component of the transport system for branched-chain amino acids
GSN03_04470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSN03_04535	COG0586	Pfam SNARE associated Golgi protein
GSN03_04565	COG0531	amino acid
GSN03_04570	COG0475	glutathione-regulated potassium exporter activity
GSN03_04580	COG1737	Transcriptional regulator
GSN03_04590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GSN03_04590	COG1263	PTS System
GSN03_04600	COG2259	Doxx family
GSN03_04620	COG1522	sequence-specific DNA binding
GSN03_04645	COG2076	Multidrug Resistance protein
GSN03_04650	COG1309	transcriptional regulator
GSN03_04655	COG2814	Major facilitator Superfamily
GSN03_04660	COG1733	regulation of RNA biosynthetic process
GSN03_04680	COG4533	DNA binding
GSN03_04685	COG2211	Major facilitator Superfamily
GSN03_04695	COG0693	protein deglycase activity
GSN03_04705	COG0531	amino acid
GSN03_04715	COG1012	belongs to the aldehyde dehydrogenase family
GSN03_04720	COG1132	(ABC) transporter
GSN03_04725	COG1132	(ABC) transporter
GSN03_04730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSN03_04735	COG0765	amino acid transport
GSN03_04740	COG1126	abc transporter atp-binding protein
GSN03_04755	COG0189	ligase activity
GSN03_04770	COG3679	Belongs to the UPF0342 family
GSN03_04775	COG0028	Belongs to the TPP enzyme family
GSN03_04780	COG3527	Alpha-acetolactate decarboxylase
GSN03_04785	COG0463	Glycosyl transferase, family 2
GSN03_04790	COG1216	Glycosyl transferase, family 2
GSN03_04795	COG2094	Belongs to the DNA glycosylase MPG family
GSN03_04800	COG0561	phosphatase activity
GSN03_04810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GSN03_04815	COG0318	PFAM AMP-dependent synthetase and ligase
GSN03_04820	COG0586	Pfam SNARE associated Golgi protein
GSN03_04830	COG0789	Transcriptional regulator
GSN03_04830	COG4978	Transcriptional regulator
GSN03_04840	COG0659	secondary active sulfate transmembrane transporter activity
GSN03_04855	COG0653	protein targeting
GSN03_04860	COG2244	polysaccharide biosynthetic process
GSN03_04870	COG0860	N-Acetylmuramoyl-L-alanine amidase
GSN03_04875	COG4196	transglutaminase domain protein
GSN03_04890	COG1696	Membrane protein involved in D-alanine export
GSN03_04905	COG1024	Enoyl-CoA hydratase
GSN03_04925	COG1363	Peptidase, m42
GSN03_04940	COG2318	DinB family
GSN03_04960	COG0579	oxidoreductase
GSN03_04985	COG0601	transmembrane transport
GSN03_04990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSN03_04995	COG0444	Belongs to the ABC transporter superfamily
GSN03_05000	COG4608	Belongs to the ABC transporter superfamily
GSN03_05025	COG0477	Major facilitator Superfamily
GSN03_05030	COG3290	protein histidine kinase activity
GSN03_05035	COG4565	transcriptional regulatory protein
GSN03_05040	COG3181	Tripartite tricarboxylate transporter family receptor
GSN03_05070	COG1842	Phage shock protein A
GSN03_05080	COG0477	Major facilitator Superfamily
GSN03_05120	COG1183	phosphatidylcholine synthase activity
GSN03_05185	COG2814	Major facilitator Superfamily
GSN03_05190	COG0640	Transcriptional regulator
GSN03_05210	COG2376	Dihydroxyacetone kinase
GSN03_05220	COG2376	Dihydroxyacetone kinase
GSN03_05250	COG0457	Tetratricopeptide repeat
GSN03_05260	COG2720	vancomycin resistance protein
GSN03_05285	COG0596	Alpha beta hydrolase
GSN03_05315	COG1388	LysM domain
GSN03_05335	COG2807	transmembrane transport
GSN03_05340	COG2186	Transcriptional regulator
GSN03_05370	COG0420	3'-5' exonuclease activity
GSN03_05375	COG4717	serine-type aminopeptidase activity
GSN03_05390	COG0346	lactoylglutathione lyase activity
GSN03_05400	COG2267	carboxylic ester hydrolase activity
GSN03_05415	COG3620	sequence-specific DNA binding
GSN03_05420	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GSN03_05425	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GSN03_05430	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GSN03_05435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GSN03_05450	COG3973	AAA domain
GSN03_05470	COG1846	Transcriptional regulator
GSN03_05480	COG0537	adenosine 5'-monophosphoramidase activity
GSN03_05485	COG1131	(ABC) transporter
GSN03_05490	COG4473	ABC transporter
GSN03_05500	COG0247	lactate metabolic process
GSN03_05505	COG1139	Iron-sulfur cluster binding protein
GSN03_05510	COG1556	Lactate utilization protein
GSN03_05525	COG3402	PFAM membrane-flanked domain
GSN03_05530	COG3428	Bacterial PH domain
GSN03_05570	COG3402	PFAM membrane-flanked domain
GSN03_05575	COG3428	Bacterial PH domain
GSN03_05580	COG2329	Antibiotic biosynthesis monooxygenase
GSN03_05585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GSN03_05595	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GSN03_05625	COG1309	transcriptional regulator
GSN03_05630	COG1511	domain protein
GSN03_05655	COG2318	DinB family
GSN03_05665	COG1609	Transcriptional regulator
GSN03_05675	COG1234	tRNA 3'-trailer cleavage
GSN03_05680	COG0095	Lipoate-protein ligase
GSN03_05690	COG0318	PFAM AMP-dependent synthetase and ligase
GSN03_05705	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GSN03_05715	COG4208	sulfate ABC transporter
GSN03_05725	COG1309	transcriptional regulator
GSN03_05730	COG1408	metallophosphoesterase
GSN03_05735	COG1078	dGTPase activity
GSN03_05745	COG1595	DNA-templated transcription, initiation
GSN03_05750	COG3708	Transcriptional regulator
GSN03_05750	COG2207	Transcriptional regulator
GSN03_05755	COG2205	protein histidine kinase activity
GSN03_05760	COG0745	RESPONSE REGULATOR receiver
GSN03_05775	COG0501	Belongs to the peptidase M48B family
GSN03_05780	COG0697	spore germination
GSN03_05800	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GSN03_05805	COG2224	Isocitrate lyase
GSN03_05815	COG1278	Cold shock
GSN03_05830	COG4903	ComK protein
GSN03_05840	COG0398	Pfam SNARE associated Golgi protein
GSN03_05850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GSN03_05855	COG1074	ATP-dependent DNA helicase activity
GSN03_05910	COG0179	Fumarylacetoacetate (FAA) hydrolase
GSN03_05935	COG0367	asparagine synthase
GSN03_05945	COG0753	catalase activity
GSN03_05950	COG0004	ammonium transporteR
GSN03_05970	COG2996	Protein conserved in bacteria
GSN03_05975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GSN03_05985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSN03_06000	COG0561	phosphatase activity
GSN03_06020	COG2267	carboxylic ester hydrolase activity
GSN03_06035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GSN03_06040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GSN03_06045	COG5504	Zn-dependent protease
GSN03_06055	COG0180	Tryptophanyl-tRNA synthetase
GSN03_06065	COG4166	transmembrane transport
GSN03_06070	COG0601	transmembrane transport
GSN03_06075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSN03_06080	COG0444	Belongs to the ABC transporter superfamily
GSN03_06085	COG4608	Belongs to the ABC transporter superfamily
GSN03_06090	COG0534	Mate efflux family protein
GSN03_06095	COG4166	transmembrane transport
GSN03_06110	COG0861	Integral membrane protein TerC family
GSN03_06120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GSN03_06130	COG1164	Oligoendopeptidase f
GSN03_06140	COG2346	COG2346, Truncated hemoglobins
GSN03_06145	COG4116	CYTH
GSN03_06155	COG2357	RelA SpoT domain protein
GSN03_06165	COG0564	pseudouridine synthase activity
GSN03_06175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GSN03_06180	COG0772	Belongs to the SEDS family
GSN03_06190	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GSN03_06205	COG1091	dTDP-4-dehydrorhamnose reductase activity
GSN03_06250	COG2153	protein acetylation
GSN03_06260	COG2382	esterase
GSN03_06285	COG5492	domain, Protein
GSN03_06290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GSN03_06300	COG0512	Glutamine amidotransferase of anthranilate synthase
GSN03_06300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GSN03_06305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GSN03_06310	COG0134	indole-3-glycerol-phosphate synthase activity
GSN03_06325	COG0159	tryptophan synthase activity
GSN03_06335	COG1620	l-lactate permease
GSN03_06340	COG5634	Uncharacterized conserved protein (DUF2278)
GSN03_06390	COG2226	methyltransferase
GSN03_06410	COG0508	dehydrogenase complex catalyzes the overall conversion of
GSN03_06415	COG0567	Dehydrogenase, E1 component
GSN03_06420	COG1476	TRANSCRIPTIONal
GSN03_06480	COG1686	Belongs to the peptidase S11 family
GSN03_06485	COG0681	Belongs to the peptidase S26 family
GSN03_06520	COG1012	belongs to the aldehyde dehydrogenase family
GSN03_06525	COG3842	ATPase activity
GSN03_06530	COG1176	ABC-type spermidine putrescine transport system, permease component I
GSN03_06535	COG1177	transmembrane transport
GSN03_06540	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GSN03_06545	COG0671	phosphoesterase, PA-phosphatase related
GSN03_06550	COG2409	Drug exporters of the RND superfamily
GSN03_06560	COG0564	pseudouridine synthase activity
GSN03_06570	COG2340	Cysteine-rich secretory protein family
GSN03_06575	COG0247	lactate metabolic process
GSN03_06580	COG0277	FAD linked oxidase domain protein
GSN03_06585	COG3835	regulator
GSN03_06595	COG0745	RESPONSE REGULATOR receiver
GSN03_06600	COG5002	protein histidine kinase activity
GSN03_06605	COG2186	Transcriptional regulator
GSN03_06620	COG1556	Lactate utilization protein
GSN03_06625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GSN03_06635	COG2116	formate transmembrane transporter activity
GSN03_06640	COG0861	Integral membrane protein TerC family
GSN03_06645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GSN03_06655	COG2030	dehydratase
GSN03_06675	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_06680	COG3243	poly(R)-hydroxyalkanoic acid synthase
GSN03_06690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GSN03_06705	COG1840	ABC-type Fe3 transport system, periplasmic component
GSN03_06710	COG3842	ATPase activity
GSN03_06735	COG1349	DNA-binding transcription factor activity
GSN03_06745	COG0235	Class ii aldolase
GSN03_06755	COG2861	carbohydrate metabolic process
GSN03_06765	COG3852	Histidine kinase
GSN03_06770	COG1846	Transcriptional regulator
GSN03_06780	COG2318	DinB family
GSN03_06785	COG5002	protein histidine kinase activity
GSN03_06795	COG0720	synthase
GSN03_06810	COG4873	Protein conserved in bacteria
GSN03_06835	COG1780	Probably involved in ribonucleotide reductase function
GSN03_06850	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GSN03_06855	COG0531	amino acid
GSN03_06860	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GSN03_06880	COG1012	belongs to the aldehyde dehydrogenase family
GSN03_06890	COG1725	Transcriptional regulator
GSN03_06895	COG1131	(ABC) transporter
GSN03_06905	COG1131	(ABC) transporter
GSN03_06910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GSN03_06925	COG1522	sequence-specific DNA binding
GSN03_06935	COG1335	isochorismatase
GSN03_06945	COG1619	proteins homologs of microcin C7 resistance protein MccF
GSN03_06950	COG2070	2-Nitropropane dioxygenase
GSN03_06955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GSN03_06965	COG1696	Membrane protein involved in D-alanine export
GSN03_06990	COG0716	FMN binding
GSN03_07000	COG3173	Aminoglycoside phosphotransferase
GSN03_07015	COG0534	Mate efflux family protein
GSN03_07040	COG1846	Transcriptional regulator
GSN03_07050	COG1301	dicarboxylic acid transport
GSN03_07055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GSN03_07065	COG3874	Sporulation protein YtfJ
GSN03_07090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GSN03_07095	COG0028	Belongs to the TPP enzyme family
GSN03_07100	COG0440	acetolactate synthase activity
GSN03_07110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GSN03_07160	COG0107	imidazoleglycerol-phosphate synthase activity
GSN03_07170	COG0140	phosphoribosyl-ATP diphosphatase activity
GSN03_07175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GSN03_07185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSN03_07190	COG1183	phosphatidylcholine synthase activity
GSN03_07195	COG1368	sulfuric ester hydrolase activity
GSN03_07205	COG0019	diaminopimelate decarboxylase activity
GSN03_07215	COG0175	sulfate reduction
GSN03_07220	COG2046	Belongs to the sulfate adenylyltransferase family
GSN03_07225	COG0529	Catalyzes the synthesis of activated sulfate
GSN03_07230	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GSN03_07250	COG1648	precorrin-2 dehydrogenase activity
GSN03_07255	COG0733	neurotransmitter:sodium symporter activity
GSN03_07275	COG1757	Na H antiporter
GSN03_07290	COG4758	membrane
GSN03_07295	COG4585	Histidine kinase
GSN03_07300	COG2197	response regulator
GSN03_07310	COG1114	Component of the transport system for branched-chain amino acids
GSN03_07360	COG0730	response to heat
GSN03_07365	COG0306	phosphate transporter
GSN03_07370	COG1392	Phosphate transport regulator
GSN03_07375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GSN03_07395	COG1801	Protein of unknown function DUF72
GSN03_07405	COG0582	viral genome integration into host DNA
GSN03_07410	COG5002	protein histidine kinase activity
GSN03_07425	COG0392	lysyltransferase activity
GSN03_07425	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GSN03_07440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GSN03_07445	COG1686	Belongs to the peptidase S11 family
GSN03_07450	COG2715	membrane protein required for spore maturation
GSN03_07455	COG0700	Nucleoside recognition
GSN03_07460	COG1187	pseudouridine synthase activity
GSN03_07470	COG1333	cytochrome c biogenesis protein
GSN03_07475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GSN03_07480	COG0745	RESPONSE REGULATOR receiver
GSN03_07485	COG5002	protein histidine kinase activity
GSN03_07490	COG2096	Adenosyltransferase
GSN03_07495	COG1388	LysM domain
GSN03_07505	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GSN03_07510	COG1141	Ferredoxin
GSN03_07520	COG0514	ATP-dependent DNA helicase (RecQ)
GSN03_07525	COG1266	CAAX protease self-immunity
GSN03_07535	COG1408	metallophosphoesterase
GSN03_07550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GSN03_07570	COG0492	ferredoxin-NADP+ reductase activity
GSN03_07585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GSN03_07595	COG1304	FMN binding
GSN03_07645	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GSN03_07660	COG0142	geranyltranstransferase activity
GSN03_07665	COG2226	methyltransferase
GSN03_07670	COG0142	geranyltranstransferase activity
GSN03_07685	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GSN03_07695	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GSN03_07700	COG0457	Tetratricopeptide repeat
GSN03_07720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GSN03_07725	COG2010	Cytochrome c
GSN03_07725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GSN03_07730	COG4347	Protein of unknown function (DUF1405)
GSN03_07745	COG2738	Putative neutral zinc metallopeptidase
GSN03_07755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSN03_07760	COG1694	Mazg nucleotide pyrophosphohydrolase
GSN03_07765	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GSN03_07770	COG1803	Methylglyoxal synthase
GSN03_07780	COG0438	transferase activity, transferring glycosyl groups
GSN03_07785	COG0617	tRNA 3'-terminal CCA addition
GSN03_07795	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GSN03_07810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GSN03_07810	COG1199	ATP-dependent helicase activity
GSN03_07830	COG3935	DnaD domain protein
GSN03_07835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GSN03_07845	COG4499	WXG100 protein secretion system (Wss), protein YukC
GSN03_07845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GSN03_07850	COG3331	DNA recombination
GSN03_07890	COG3599	regulation of cell shape
GSN03_07900	COG0116	Belongs to the methyltransferase superfamily
GSN03_07910	COG1199	ATP-dependent helicase activity
GSN03_07915	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GSN03_07925	COG0024	Methionine aminopeptidase
GSN03_07935	COG2233	PERMEase
GSN03_07940	COG2311	Membrane
GSN03_07945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GSN03_07955	COG0456	acetyltransferase
GSN03_08005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GSN03_08030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GSN03_08045	COG1215	transferase activity, transferring glycosyl groups
GSN03_08050	COG0438	transferase activity, transferring glycosyl groups
GSN03_08065	COG0454	-acetyltransferase
GSN03_08085	COG0328	RNA-DNA hybrid ribonuclease activity
GSN03_08120	COG3403	YqcI/YcgG family
GSN03_08125	COG1280	lysine exporter protein (LysE YggA)
GSN03_08140	COG3162	membrane
GSN03_08145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GSN03_08150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GSN03_08160	COG0475	glutathione-regulated potassium exporter activity
GSN03_08165	COG0789	Transcriptional regulator
GSN03_08165	COG4978	Transcriptional regulator
GSN03_08175	COG2323	membrane
GSN03_08180	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GSN03_08215	COG2814	Major facilitator Superfamily
GSN03_08230	COG1923	regulation of RNA biosynthetic process
GSN03_08250	COG2201	protein-glutamate methylesterase activity
GSN03_08260	COG1776	CheC inhibitor of MCP methylation
GSN03_08260	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GSN03_08295	COG0861	Integral membrane protein TerC family
GSN03_08305	COG3383	formate dehydrogenase (NAD+) activity
GSN03_08310	COG2427	Protein of unknown function (DUF1641)
GSN03_08315	COG5609	conserved protein (DUF2294)
GSN03_08320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GSN03_08330	COG2116	formate transmembrane transporter activity
GSN03_08335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GSN03_08340	COG0303	'Molybdopterin
GSN03_08345	COG0314	molybdopterin synthase activity
GSN03_08350	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GSN03_08360	COG0489	protein tyrosine kinase activity
GSN03_08365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GSN03_08370	COG0741	lytic transglycosylase activity
GSN03_08380	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GSN03_08385	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GSN03_08385	COG1776	CheC inhibitor of MCP methylation
GSN03_08395	COG1338	Plays a role in the flagellum-specific transport system
GSN03_08400	COG1987	bacterial-type flagellum assembly
GSN03_08410	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GSN03_08420	COG1419	protein localization to endoplasmic reticulum
GSN03_08425	COG4786	Flagellar basal body rod
GSN03_08430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSN03_08460	COG0412	Dienelactone hydrolase
GSN03_08465	COG2329	Antibiotic biosynthesis monooxygenase
GSN03_08495	COG3842	ATPase activity
GSN03_08500	COG0725	ABC transporter, periplasmic molybdate-binding protein
GSN03_08510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GSN03_08540	COG0406	alpha-ribazole phosphatase activity
GSN03_08560	COG1846	Transcriptional regulator
GSN03_08570	COG0367	asparagine synthase
GSN03_08600	COG1802	Transcriptional regulator
GSN03_08605	COG0697	spore germination
GSN03_08610	COG1216	Glycosyl transferase, family 2
GSN03_08610	COG0438	transferase activity, transferring glycosyl groups
GSN03_08615	COG1757	Na H antiporter
GSN03_08620	COG0789	Transcriptional regulator
GSN03_08625	COG4221	oxidoreductase activity
GSN03_08630	COG0114	fumarate hydratase activity
GSN03_08650	COG0534	Mate efflux family protein
GSN03_08655	COG3340	Belongs to the peptidase S51 family
GSN03_08675	COG0785	Cytochrome C biogenesis protein
GSN03_08680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GSN03_08695	COG3048	D-serine ammonia-lyase activity
GSN03_08700	COG2733	membrane
GSN03_08735	COG1131	(ABC) transporter
GSN03_08755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GSN03_08760	COG0528	UMP kinase activity
GSN03_08770	COG1027	Aspartate ammonia-lyase
GSN03_08775	COG0281	malic enzyme
GSN03_08780	COG4191	Histidine kinase
GSN03_08785	COG0784	Response regulator, receiver
GSN03_08790	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GSN03_08800	COG2502	aspartate--ammonia ligase
GSN03_08805	COG3620	sequence-specific DNA binding
GSN03_08835	COG1051	belongs to the nudix hydrolase family
GSN03_08840	COG0860	N-Acetylmuramoyl-L-alanine amidase
GSN03_08850	COG2814	Major facilitator Superfamily
GSN03_08870	COG1595	DNA-templated transcription, initiation
GSN03_08890	COG0477	Major facilitator Superfamily
GSN03_08895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GSN03_08905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GSN03_08910	COG2223	nitrite transmembrane transporter activity
GSN03_08915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GSN03_08930	COG2244	polysaccharide biosynthetic process
GSN03_08935	COG0733	neurotransmitter:sodium symporter activity
GSN03_08945	COG5566	PFAM Mor transcription activator
GSN03_08950	COG2323	membrane
GSN03_08970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GSN03_08980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GSN03_08985	COG0028	Belongs to the TPP enzyme family
GSN03_09005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GSN03_09030	COG2814	Major facilitator Superfamily
GSN03_09035	COG3384	dioxygenase
GSN03_09050	COG3279	Response regulator of the LytR AlgR family
GSN03_09055	COG0427	acetyl-CoA hydrolase
GSN03_09090	COG4166	transmembrane transport
GSN03_09130	COG0737	Belongs to the 5'-nucleotidase family
GSN03_09140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSN03_09165	COG1914	H( )-stimulated, divalent metal cation uptake system
GSN03_09170	COG1054	Belongs to the UPF0176 family
GSN03_09180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GSN03_09185	COG0531	amino acid
GSN03_09215	COG2031	fatty acid transporter
GSN03_09225	COG2390	Transcriptional regulator
GSN03_09240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GSN03_09245	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GSN03_09260	COG4846	Membrane protein involved in cytochrome C biogenesis
GSN03_09285	COG0006	proline dipeptidase activity
GSN03_09290	COG2132	Multicopper oxidase
GSN03_09300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GSN03_09310	COG0583	DNA-binding transcription factor activity
GSN03_09330	COG1114	Component of the transport system for branched-chain amino acids
GSN03_09340	COG1276	copper resistance
GSN03_09340	COG2372	response to copper ion
GSN03_09345	COG4549	nuclear export factor GLE1
GSN03_09355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GSN03_09375	COG0697	spore germination
GSN03_09380	COG0583	DNA-binding transcription factor activity
GSN03_09385	COG1959	2 iron, 2 sulfur cluster binding
GSN03_09390	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GSN03_09395	COG0778	Nitroreductase
GSN03_09410	COG0628	permease
GSN03_09425	COG1231	oxidoreductase activity
GSN03_09430	COG0523	cobalamin synthesis protein
GSN03_09440	COG0411	ABC transporter
GSN03_09460	COG0583	DNA-binding transcription factor activity
GSN03_09470	COG1942	4-Oxalocrotonate Tautomerase
GSN03_09485	COG0346	lactoylglutathione lyase activity
GSN03_09495	COG1271	oxidase subunit
GSN03_09500	COG1294	oxidase, subunit
GSN03_09505	COG4988	ABC transporter
GSN03_09510	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GSN03_09540	COG1686	Belongs to the peptidase S11 family
GSN03_09550	COG0791	NLP P60 protein
GSN03_09550	COG1388	LysM domain
GSN03_09560	COG1132	(ABC) transporter
GSN03_09565	COG0745	RESPONSE REGULATOR receiver
GSN03_09570	COG5002	protein histidine kinase activity
GSN03_09575	COG0300	oxidoreductase activity
GSN03_09580	COG4122	O-methyltransferase activity
GSN03_09610	COG0460	homoserine dehydrogenase
GSN03_09635	COG1316	TRANSCRIPTIONal
GSN03_09645	COG0745	RESPONSE REGULATOR receiver
GSN03_09650	COG5002	protein histidine kinase activity
GSN03_09665	COG1285	pathogenesis
GSN03_09670	COG1247	-acetyltransferase
GSN03_09690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GSN03_09700	COG1082	Xylose isomerase domain protein TIM barrel
GSN03_09710	COG2814	Major facilitator Superfamily
GSN03_09715	COG1279	arginine transmembrane transporter activity
GSN03_09720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSN03_09730	COG1752	Esterase of the alpha-beta hydrolase superfamily
GSN03_09765	COG0577	efflux transmembrane transporter activity
GSN03_09770	COG2002	toxin-antitoxin pair type II binding
GSN03_09775	COG1404	Belongs to the peptidase S8 family
GSN03_09780	COG0640	Transcriptional regulator
GSN03_09785	COG0667	Aldo Keto reductase
GSN03_09790	COG2814	Major facilitator Superfamily
GSN03_09815	COG0840	transmembrane signaling receptor activity
GSN03_09830	COG3949	Membrane
GSN03_09835	COG0783	Belongs to the Dps family
GSN03_09850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSN03_09860	COG1231	oxidoreductase activity
GSN03_09865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSN03_09870	COG4989	oxidoreductase activity
GSN03_09875	COG0523	cobalamin synthesis protein
GSN03_09880	COG0456	acetyltransferase
GSN03_09885	COG0803	Belongs to the bacterial solute-binding protein 9 family
GSN03_09900	COG1902	pentaerythritol trinitrate reductase activity
GSN03_09905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GSN03_09915	COG4166	transmembrane transport
GSN03_09930	COG0406	alpha-ribazole phosphatase activity
GSN03_09940	COG5337	Spore coat protein CotH
GSN03_09945	COG1051	belongs to the nudix hydrolase family
GSN03_09950	COG0586	Pfam SNARE associated Golgi protein
GSN03_09955	COG2244	polysaccharide biosynthetic process
GSN03_09965	COG0701	Predicted permease
GSN03_09970	COG3689	TIGRFAM TIGR03943 family protein
GSN03_09975	COG1607	acyl-coa hydrolase
GSN03_09985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GSN03_10000	COG0702	epimerase
GSN03_10005	COG2839	Protein conserved in bacteria
GSN03_10010	COG1253	flavin adenine dinucleotide binding
GSN03_10025	COG1114	Component of the transport system for branched-chain amino acids
GSN03_10030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GSN03_10050	COG0860	N-Acetylmuramoyl-L-alanine amidase
GSN03_10060	COG1876	peptidase activity
GSN03_10075	COG2211	Major facilitator Superfamily
GSN03_10100	COG0860	N-Acetylmuramoyl-L-alanine amidase
GSN03_10105	COG2368	4-hydroxyphenylacetate
GSN03_10115	COG0196	riboflavin kinase activity
GSN03_10130	COG0251	oxidation-reduction process
GSN03_10140	COG3971	2-oxopent-4-enoate hydratase activity
GSN03_10160	COG1942	4-Oxalocrotonate Tautomerase
GSN03_10170	COG0561	phosphatase activity
GSN03_10175	COG1846	Transcriptional regulator
GSN03_10180	COG2814	Major facilitator Superfamily
GSN03_10190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GSN03_10195	COG4106	trans-aconitate 2-methyltransferase activity
GSN03_10210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSN03_10215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSN03_10240	COG0456	acetyltransferase
GSN03_10265	COG3874	Sporulation protein YtfJ
GSN03_10290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GSN03_10315	COG0346	lactoylglutathione lyase activity
GSN03_10325	COG0604	alcohol dehydrogenase
GSN03_10330	COG1595	DNA-templated transcription, initiation
GSN03_10365	COG0386	Belongs to the glutathione peroxidase family
GSN03_10370	COG1305	Transglutaminase-like
GSN03_10375	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GSN03_10380	COG0714	Associated with various cellular activities
GSN03_10395	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GSN03_10400	COG1140	nitrate reductase beta subunit
GSN03_10405	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GSN03_10410	COG2181	nitrate reductase activity
GSN03_10415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GSN03_10420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GSN03_10425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GSN03_10430	COG0303	'Molybdopterin
GSN03_10435	COG0314	molybdopterin synthase activity
GSN03_10445	COG2223	nitrite transmembrane transporter activity
GSN03_10465	COG1648	precorrin-2 dehydrogenase activity
GSN03_10475	COG1587	Uroporphyrinogen-III synthase
GSN03_10475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GSN03_10480	COG2146	nitrite reductase [NAD(P)H] activity
GSN03_10485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GSN03_10490	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GSN03_10515	COG2359	stage V sporulation protein S
GSN03_10525	COG1418	mRNA catabolic process
GSN03_10530	COG0488	(ABC) transporter
GSN03_10550	COG1413	lyase activity
GSN03_10565	COG2521	methyltransferase
GSN03_10565	COG2136	Putative SAM-dependent methyltransferase
GSN03_10625	COG0017	Asparaginyl-tRNA synthetase
GSN03_10630	COG0733	neurotransmitter:sodium symporter activity
GSN03_10655	COG2610	gluconate transmembrane transporter activity
GSN03_10660	COG1454	alcohol dehydrogenase
GSN03_10665	COG1794	racemase activity, acting on amino acids and derivatives
GSN03_10675	COG0456	acetyltransferase
GSN03_10680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GSN03_10685	COG1131	(ABC) transporter
GSN03_10690	COG4473	ABC transporter
GSN03_10700	COG0546	phosphoglycolate phosphatase activity
GSN03_10755	COG0768	penicillin binding
GSN03_10765	COG0204	Acyl-transferase
GSN03_10770	COG1272	protein, Hemolysin III
GSN03_10780	COG0805	protein transport
GSN03_10790	COG1307	EDD domain protein, DegV family
GSN03_10795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GSN03_10800	COG1999	signal sequence binding
GSN03_10810	COG0367	asparagine synthase
GSN03_10825	COG0860	N-Acetylmuramoyl-L-alanine amidase
GSN03_10830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GSN03_10835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GSN03_10855	COG1335	isochorismatase
GSN03_10865	COG0668	transmembrane transport
GSN03_10870	COG4585	Histidine kinase
GSN03_10870	COG2203	Gaf domain
GSN03_10875	COG2197	response regulator
GSN03_10880	COG1737	Transcriptional regulator
GSN03_10885	COG1064	alcohol dehydrogenase
GSN03_10910	COG1070	Carbohydrate kinase
GSN03_10920	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GSN03_10940	COG0517	IMP dehydrogenase activity
GSN03_10940	COG1125	glycine betaine transport
GSN03_10945	COG1174	glycine betaine transport
GSN03_10980	COG1253	flavin adenine dinucleotide binding
GSN03_10985	COG1012	belongs to the aldehyde dehydrogenase family
GSN03_10990	COG5506	Protein of unknown function (DUF1694)
GSN03_11005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GSN03_11010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GSN03_11015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GSN03_11020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GSN03_11025	COG0456	acetyltransferase
GSN03_11030	COG3829	transcription factor binding
GSN03_11035	COG1509	lysine 2,3-aminomutase activity
GSN03_11070	COG0515	serine threonine protein kinase
GSN03_11070	COG3064	Membrane
GSN03_11070	COG4991	sh3 domain protein
GSN03_11075	COG4326	sporulation control protein
GSN03_11080	COG0671	phosphoesterase, PA-phosphatase related
GSN03_11085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GSN03_11090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GSN03_11095	COG0582	viral genome integration into host DNA
GSN03_11110	COG1396	sequence-specific DNA binding
GSN03_11140	COG1484	DNA-dependent DNA replication
GSN03_11150	COG2002	toxin-antitoxin pair type II binding
GSN03_11195	COG0582	viral genome integration into host DNA
GSN03_11235	COG1802	Transcriptional regulator
GSN03_11235	COG4626	Terminase
GSN03_11245	COG0740	serine-type endopeptidase activity
GSN03_11325	COG5632	N-Acetylmuramoyl-L-alanine amidase
GSN03_11345	COG0582	viral genome integration into host DNA
GSN03_11400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GSN03_11430	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_11450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GSN03_11450	COG4499	WXG100 protein secretion system (Wss), protein YukC
GSN03_11460	COG2814	Major facilitator Superfamily
GSN03_11465	COG0372	Belongs to the citrate synthase family
GSN03_11470	COG2079	MmgE PrpD family protein
GSN03_11475	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GSN03_11480	COG1960	acyl-CoA dehydrogenase activity
GSN03_11485	COG2084	Dehydrogenase
GSN03_11495	COG1280	lysine exporter protein (LysE YggA)
GSN03_11500	COG1024	Enoyl-CoA hydratase
GSN03_11515	COG0420	3'-5' exonuclease activity
GSN03_11520	COG0419	ATPase involved in DNA repair
GSN03_11535	COG2223	nitrite transmembrane transporter activity
GSN03_11540	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_11545	COG1169	isochorismate synthase
GSN03_11550	COG1021	2,3-dihydroxybenzoate-AMP ligase
GSN03_11555	COG3433	isochorismatase activity
GSN03_11555	COG1535	isochorismatase
GSN03_11560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GSN03_11565	COG3251	PFAM MbtH domain protein
GSN03_11570	COG2814	Major facilitator Superfamily
GSN03_11585	COG0776	regulation of translation
GSN03_11595	COG2318	DinB family
GSN03_11600	COG1115	amino acid carrier protein
GSN03_11615	COG2329	Antibiotic biosynthesis monooxygenase
GSN03_11620	COG1187	pseudouridine synthase activity
GSN03_11625	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GSN03_11630	COG3655	Transcriptional regulator
GSN03_11640	COG1136	(ABC) transporter
GSN03_11650	COG2814	Major facilitator Superfamily
GSN03_11665	COG0028	Belongs to the TPP enzyme family
GSN03_11695	COG2267	carboxylic ester hydrolase activity
GSN03_11705	COG1595	DNA-templated transcription, initiation
GSN03_11725	COG1846	Transcriptional regulator
GSN03_11740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSN03_11745	COG1309	transcriptional regulator
GSN03_11755	COG0697	spore germination
GSN03_11760	COG0531	amino acid
GSN03_11780	COG1247	-acetyltransferase
GSN03_11820	COG0596	Alpha beta hydrolase
GSN03_11825	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GSN03_11835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSN03_11875	COG0561	phosphatase activity
GSN03_11885	COG0583	DNA-binding transcription factor activity
GSN03_11890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GSN03_11905	COG0583	DNA-binding transcription factor activity
GSN03_11910	COG2258	MOSC domain
GSN03_11925	COG1132	(ABC) transporter
GSN03_11930	COG1132	(ABC) transporter
GSN03_11935	COG0582	viral genome integration into host DNA
GSN03_11955	COG1396	sequence-specific DNA binding
GSN03_11980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GSN03_11995	COG1595	DNA-templated transcription, initiation
GSN03_12015	COG1649	PFAM Uncharacterised BCR, COG1649
GSN03_12035	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GSN03_12040	COG2971	BadF BadG BcrA BcrD
GSN03_12095	COG0577	efflux transmembrane transporter activity
GSN03_12095	COG1136	(ABC) transporter
GSN03_12100	COG0500	methyltransferase
GSN03_12110	COG0693	protein deglycase activity
GSN03_12140	COG2195	Cleaves the N-terminal amino acid of tripeptides
GSN03_12150	COG0110	maltose O-acetyltransferase activity
GSN03_12155	COG1686	Belongs to the peptidase S11 family
GSN03_12200	COG0768	penicillin binding
GSN03_12205	COG0745	RESPONSE REGULATOR receiver
GSN03_12210	COG2205	protein histidine kinase activity
GSN03_12215	COG1136	(ABC) transporter
GSN03_12220	COG0577	efflux transmembrane transporter activity
GSN03_12230	COG1595	DNA-templated transcription, initiation
GSN03_12240	COG0768	penicillin binding
GSN03_12245	COG0768	penicillin binding
GSN03_12255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GSN03_12285	COG0697	spore germination
GSN03_12295	COG1349	DNA-binding transcription factor activity
GSN03_12300	COG0546	phosphoglycolate phosphatase activity
GSN03_12305	COG3397	chitin binding
GSN03_12310	COG0823	Involved in the tonB-independent uptake of proteins
GSN03_12320	COG1408	metallophosphoesterase
GSN03_12330	COG1131	(ABC) transporter
GSN03_12340	COG1309	transcriptional regulator
GSN03_12350	COG1960	acyl-CoA dehydrogenase activity
GSN03_12355	COG0439	Biotin carboxylase
GSN03_12360	COG0511	ligase activity, forming carbon-carbon bonds
GSN03_12365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GSN03_12370	COG1024	Enoyl-CoA hydratase
GSN03_12375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GSN03_12380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GSN03_12415	COG2318	DinB family
GSN03_12420	COG1686	Belongs to the peptidase S11 family
GSN03_12445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GSN03_12475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GSN03_12505	COG1733	regulation of RNA biosynthetic process
GSN03_12510	COG2226	methyltransferase
GSN03_12545	COG0697	spore germination
GSN03_12550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSN03_12585	COG2323	membrane
GSN03_12590	COG2132	Multicopper oxidase
GSN03_12605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSN03_12610	COG0697	spore germination
GSN03_12615	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GSN03_12620	COG0201	protein transport
GSN03_12630	COG0737	Belongs to the 5'-nucleotidase family
GSN03_12635	COG3227	Zinc metalloprotease (Elastase)
GSN03_12640	COG1523	belongs to the glycosyl hydrolase 13 family
GSN03_12655	COG0076	glutamate decarboxylase activity
GSN03_12660	COG0657	acetylesterase activity
GSN03_12665	COG1073	alpha beta
GSN03_12675	COG0577	efflux transmembrane transporter activity
GSN03_12680	COG1136	(ABC) transporter
GSN03_12695	COG5002	protein histidine kinase activity
GSN03_12700	COG0745	RESPONSE REGULATOR receiver
GSN03_12705	COG1011	Hydrolase
GSN03_12730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSN03_12735	COG1183	phosphatidylcholine synthase activity
GSN03_12745	COG3961	Belongs to the TPP enzyme family
GSN03_12765	COG0322	excinuclease ABC activity
GSN03_12805	COG4667	esterase of the alpha-beta hydrolase superfamily
GSN03_12825	COG3878	Protein conserved in bacteria
GSN03_12865	COG1051	belongs to the nudix hydrolase family
GSN03_12870	COG0592	DNA-directed DNA polymerase activity
GSN03_12875	COG2816	NAD+ diphosphatase activity
GSN03_12885	COG2223	nitrite transmembrane transporter activity
GSN03_12890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GSN03_12920	COG0697	spore germination
GSN03_12925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSN03_12940	COG0584	glycerophosphoryl diester phosphodiesterase
GSN03_12965	COG2814	Major facilitator Superfamily
GSN03_13010	COG0768	penicillin binding
GSN03_13015	COG0671	phosphoesterase, PA-phosphatase related
GSN03_13020	COG0604	alcohol dehydrogenase
GSN03_13025	COG5002	protein histidine kinase activity
GSN03_13030	COG0745	RESPONSE REGULATOR receiver
GSN03_13040	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GSN03_13050	COG2205	protein histidine kinase activity
GSN03_13065	COG1122	ATPase activity
GSN03_13070	COG4720	Psort location CytoplasmicMembrane, score
GSN03_13075	COG1794	racemase activity, acting on amino acids and derivatives
GSN03_13080	COG1819	glycosyl
GSN03_13090	COG0768	penicillin binding
GSN03_13095	COG5002	protein histidine kinase activity
GSN03_13100	COG0561	phosphatase activity
GSN03_13135	COG2124	cytochrome p450
GSN03_13160	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GSN03_13170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSN03_13175	COG0460	homoserine dehydrogenase
GSN03_13195	COG0577	efflux transmembrane transporter activity
GSN03_13200	COG1136	(ABC) transporter
GSN03_13210	COG0488	(ABC) transporter
GSN03_13215	COG0667	Aldo Keto reductase
GSN03_13220	COG0583	DNA-binding transcription factor activity
GSN03_13230	COG2205	protein histidine kinase activity
GSN03_13235	COG0745	RESPONSE REGULATOR receiver
GSN03_13245	COG3773	Cell wall hydrolase
GSN03_13260	COG3386	PFAM SMP-30 Gluconolaconase
GSN03_13305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSN03_13320	COG2959	enzyme of heme biosynthesis
GSN03_13345	COG3483	tryptophan 2,3-dioxygenase activity
GSN03_13350	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GSN03_13355	COG3844	kynureninase activity
GSN03_13360	COG1309	transcriptional regulator
GSN03_13390	COG1349	DNA-binding transcription factor activity
GSN03_13415	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_13450	COG4176	ABC-type proline glycine betaine transport system permease component
GSN03_13455	COG4175	Glycine betaine
GSN03_13455	COG0517	IMP dehydrogenase activity
GSN03_13480	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GSN03_13485	COG2153	protein acetylation
GSN03_13490	COG3397	chitin binding
GSN03_13500	COG1819	glycosyl
GSN03_13515	COG2205	protein histidine kinase activity
GSN03_13520	COG2315	Protein conserved in bacteria
GSN03_13575	COG3973	AAA domain
GSN03_13595	COG0514	ATP-dependent DNA helicase (RecQ)
GSN03_13615	COG4637	Psort location Cytoplasmic, score
GSN03_13630	COG3397	chitin binding
GSN03_13635	COG2318	DinB family
GSN03_13650	COG1162	GTPase activity
GSN03_13655	COG1115	amino acid carrier protein
GSN03_13660	COG1012	belongs to the aldehyde dehydrogenase family
GSN03_13665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSN03_13675	COG3938	Belongs to the proline racemase family
GSN03_13680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSN03_13725	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GSN03_13725	COG0456	acetyltransferase
GSN03_13730	COG0586	Pfam SNARE associated Golgi protein
GSN03_13745	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GSN03_13750	COG4166	transmembrane transport
GSN03_13760	COG4948	Mandelate Racemase Muconate Lactonizing
GSN03_13780	COG0667	Aldo Keto reductase
GSN03_13820	COG2936	dipeptidyl-peptidase activity
GSN03_13830	COG0745	RESPONSE REGULATOR receiver
GSN03_13855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GSN03_13860	COG1164	Oligoendopeptidase f
GSN03_13865	COG0531	amino acid
GSN03_13870	COG1522	sequence-specific DNA binding
GSN03_13885	COG1307	EDD domain protein, DegV family
GSN03_13910	COG1335	isochorismatase
GSN03_13925	COG2814	Major facilitator Superfamily
GSN03_13935	COG1664	Polymer-forming cytoskeletal
GSN03_13940	COG0789	Transcriptional regulator
GSN03_13945	COG4533	DNA binding
GSN03_13950	COG0477	Major facilitator Superfamily
GSN03_13950	COG2814	Major facilitator Superfamily
GSN03_13970	COG2261	transglycosylase associated protein
GSN03_13985	COG2226	methyltransferase
GSN03_14020	COG0436	Aminotransferase
GSN03_14025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GSN03_14035	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GSN03_14050	COG1131	(ABC) transporter
GSN03_14055	COG2188	Transcriptional regulator
GSN03_14095	COG0628	permease
GSN03_14110	COG2816	NAD+ diphosphatase activity
GSN03_14130	COG2746	aminoglycoside 3-N-acetyltransferase activity
GSN03_14140	COG0697	spore germination
GSN03_14195	COG2814	Major facilitator Superfamily
GSN03_14200	COG1368	sulfuric ester hydrolase activity
GSN03_14205	COG0488	(ABC) transporter
GSN03_14215	COG1033	growth of symbiont in host cell
GSN03_14215	COG2409	Drug exporters of the RND superfamily
GSN03_14220	COG1309	transcriptional regulator
GSN03_14240	COG0287	Prephenate dehydrogenase
GSN03_14255	COG1605	Chorismate mutase
GSN03_14255	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GSN03_14310	COG0346	lactoylglutathione lyase activity
GSN03_14330	COG0579	oxidoreductase
GSN03_14335	COG1879	ABC-type sugar transport system periplasmic component
GSN03_14345	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSN03_14355	COG2390	Transcriptional regulator
GSN03_14360	COG1070	Carbohydrate kinase
GSN03_14375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSN03_14390	COG0346	lactoylglutathione lyase activity
GSN03_14395	COG2329	Antibiotic biosynthesis monooxygenase
GSN03_14415	COG1472	Belongs to the glycosyl hydrolase 3 family
GSN03_14420	COG2207	Transcriptional regulator
GSN03_14435	COG2207	Transcriptional regulator
GSN03_14450	COG3239	Fatty acid desaturase
GSN03_14465	COG3842	ATPase activity
GSN03_14470	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GSN03_14490	COG1175	transmembrane transport
GSN03_14495	COG1349	DNA-binding transcription factor activity
GSN03_14505	COG3655	Transcriptional regulator
GSN03_14520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSN03_14525	COG0346	lactoylglutathione lyase activity
GSN03_14545	COG0714	Associated with various cellular activities
GSN03_14565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GSN03_14570	COG0753	catalase activity
GSN03_14590	COG0577	efflux transmembrane transporter activity
GSN03_14595	COG1136	(ABC) transporter
GSN03_14605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GSN03_14620	COG3829	transcription factor binding
GSN03_14645	COG0714	Associated with various cellular activities
GSN03_14655	COG0778	Nitroreductase
GSN03_14660	COG1846	Transcriptional regulator
GSN03_14680	COG0179	Fumarylacetoacetate (FAA) hydrolase
GSN03_14690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GSN03_14700	COG0318	PFAM AMP-dependent synthetase and ligase
GSN03_14705	COG0183	Belongs to the thiolase family
GSN03_14710	COG1024	Enoyl-CoA hydratase
GSN03_14715	COG1250	3-hydroxyacyl-CoA dehydrogenase
GSN03_14720	COG2723	6-phospho-beta-galactosidase activity
GSN03_14725	COG1447	Phosphotransferase system cellobiose-specific component IIA
GSN03_14745	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GSN03_14755	COG2508	Transcriptional regulator
GSN03_14760	COG2814	Major facilitator Superfamily
GSN03_14770	COG1051	belongs to the nudix hydrolase family
GSN03_14775	COG2312	Erythromycin esterase
GSN03_14800	COG2207	Transcriptional regulator
GSN03_14805	COG0456	acetyltransferase
GSN03_14820	COG0697	spore germination
GSN03_14825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSN03_14845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GSN03_14845	COG0456	acetyltransferase
GSN03_14870	COG0730	response to heat
GSN03_14880	COG0833	amino acid
GSN03_14890	COG4335	DNA alkylation repair
GSN03_14920	COG0768	penicillin binding
GSN03_14930	COG3104	oligopeptide transport
GSN03_14935	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GSN03_14950	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GSN03_14955	COG1984	allophanate hydrolase subunit 2
GSN03_14960	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GSN03_14965	COG1414	Transcriptional regulator
GSN03_14985	COG1960	acyl-CoA dehydrogenase activity
GSN03_15010	COG3314	Sporulation integral membrane protein YlbJ
GSN03_15025	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GSN03_15045	COG3848	Pyruvate phosphate dikinase
GSN03_15045	COG0574	Belongs to the PEP-utilizing enzyme family
GSN03_15055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GSN03_15080	COG5002	protein histidine kinase activity
GSN03_15085	COG0745	RESPONSE REGULATOR receiver
GSN03_15100	COG1575	Belongs to the MenA family. Type 1 subfamily
GSN03_15115	COG1309	transcriptional regulator
GSN03_15125	COG2267	carboxylic ester hydrolase activity
GSN03_15135	COG0803	Belongs to the bacterial solute-binding protein 9 family
GSN03_15140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GSN03_15145	COG1121	(ABC) transporter
GSN03_15160	COG1999	signal sequence binding
GSN03_15180	COG0798	PFAM Bile acid sodium symporter
GSN03_15185	COG0346	lactoylglutathione lyase activity
GSN03_15190	COG0640	Transcriptional regulator
GSN03_15200	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_15205	COG1522	sequence-specific DNA binding
GSN03_15220	COG0346	lactoylglutathione lyase activity
GSN03_15240	COG2814	Major facilitator Superfamily
GSN03_15300	COG2226	methyltransferase
GSN03_15310	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GSN03_15335	COG1522	sequence-specific DNA binding
GSN03_15340	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GSN03_15360	COG1136	(ABC) transporter
GSN03_15365	COG0577	efflux transmembrane transporter activity
GSN03_15385	COG3850	Histidine kinase
GSN03_15385	COG5002	protein histidine kinase activity
GSN03_15395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSN03_15400	COG2271	Major facilitator Superfamily
GSN03_15405	COG1556	Lactate utilization protein
GSN03_15410	COG1139	Iron-sulfur cluster binding protein
GSN03_15420	COG0583	DNA-binding transcription factor activity
GSN03_15435	COG1619	proteins homologs of microcin C7 resistance protein MccF
GSN03_15455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GSN03_15525	COG2814	Major facilitator Superfamily
GSN03_15550	COG1876	peptidase activity
GSN03_15555	COG2843	Capsule synthesis protein
GSN03_15565	COG0477	Major facilitator Superfamily
GSN03_15580	COG1846	Transcriptional regulator
GSN03_15585	COG2814	Major facilitator Superfamily
GSN03_15600	COG2267	carboxylic ester hydrolase activity
GSN03_15625	COG5002	protein histidine kinase activity
GSN03_15640	COG1136	(ABC) transporter
GSN03_15655	COG1131	(ABC) transporter
GSN03_15720	COG4187	Peptidase family M20/M25/M40
GSN03_15725	COG1414	Transcriptional regulator
GSN03_15730	COG0833	amino acid
GSN03_15740	COG2890	protein-(glutamine-N5) methyltransferase activity
GSN03_15745	COG2031	fatty acid transporter
GSN03_15755	COG2249	NAD(P)H dehydrogenase (quinone) activity
GSN03_15805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GSN03_15810	COG2356	endonuclease I
GSN03_15815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GSN03_15820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GSN03_15845	COG1785	Belongs to the alkaline phosphatase family
GSN03_15850	COG0778	Nitroreductase
GSN03_15855	COG1733	regulation of RNA biosynthetic process
GSN03_15870	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_15880	COG1131	(ABC) transporter
GSN03_15900	COG1011	Hydrolase
GSN03_15910	COG2365	Tyrosine phosphatase family
GSN03_15930	COG0346	lactoylglutathione lyase activity
GSN03_15935	COG1940	carbohydrate kinase activity
GSN03_15955	COG0628	permease
GSN03_15975	COG0500	methyltransferase
GSN03_15985	COG0477	Major facilitator Superfamily
GSN03_16015	COG1253	flavin adenine dinucleotide binding
GSN03_16020	COG0789	Transcriptional regulator
GSN03_16030	COG0697	spore germination
GSN03_16040	COG1357	PFAM Pentapeptide repeats (8 copies)
GSN03_16045	COG3813	Protein conserved in bacteria
GSN03_16050	COG2706	6-phosphogluconolactonase activity
GSN03_16055	COG1070	Carbohydrate kinase
GSN03_16065	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GSN03_16070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GSN03_16075	COG4702	Belongs to the UPF0303 family
GSN03_16085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSN03_16110	COG0384	phenazine biosynthesis protein PhzF
GSN03_16125	COG0318	PFAM AMP-dependent synthetase and ligase
GSN03_16130	COG2249	NAD(P)H dehydrogenase (quinone) activity
GSN03_16135	COG1733	regulation of RNA biosynthetic process
GSN03_16150	COG1191	sigma factor activity
GSN03_16175	COG3226	Transcriptional regulator
GSN03_16180	COG1280	lysine exporter protein (LysE YggA)
GSN03_16200	COG0814	amino acid
GSN03_16240	COG1151	hydroxylamine reductase activity
GSN03_16250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSN03_16255	COG3409	Peptidoglycan-binding domain 1 protein
GSN03_16255	COG3757	hydrolase, family 25
GSN03_16290	COG2072	flavoprotein involved in K transport
GSN03_16335	COG0604	alcohol dehydrogenase
GSN03_16340	COG1113	amino acid transport
GSN03_16350	COG5002	protein histidine kinase activity
GSN03_16355	COG2814	Major facilitator Superfamily
GSN03_16365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GSN03_16370	COG1012	belongs to the aldehyde dehydrogenase family
GSN03_16380	COG0534	Mate efflux family protein
GSN03_16385	COG1012	belongs to the aldehyde dehydrogenase family
GSN03_16390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSN03_16405	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GSN03_16410	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GSN03_16425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GSN03_16430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSN03_16445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSN03_16450	COG3739	integral membrane protein
GSN03_16480	COG0583	DNA-binding transcription factor activity
GSN03_16495	COG3153	acetyltransferase
GSN03_16500	COG1193	negative regulation of DNA recombination
GSN03_16520	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GSN03_16525	COG1164	Oligoendopeptidase f
GSN03_16540	COG4978	Transcriptional regulator
GSN03_16540	COG0789	Transcriptional regulator
GSN03_16550	COG3781	membrane
GSN03_16565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GSN03_16605	COG3973	AAA domain
GSN03_16615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GSN03_16620	COG0640	Transcriptional regulator
GSN03_16625	COG0604	alcohol dehydrogenase
GSN03_16630	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GSN03_16640	COG0457	Tetratricopeptide repeat
GSN03_16650	COG2808	Putative FMN-binding domain
GSN03_16655	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GSN03_16665	COG0385	Bile acid
GSN03_16670	COG0277	FAD linked oxidase domain protein
GSN03_16690	COG1285	pathogenesis
GSN03_16700	COG2514	catechol 2,3-dioxygenase activity
GSN03_16705	COG2720	vancomycin resistance protein
GSN03_16730	COG1278	Cold shock
GSN03_16740	COG0716	FMN binding
GSN03_16750	COG1051	belongs to the nudix hydrolase family
GSN03_16770	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_16780	COG0165	Argininosuccinate lyase
GSN03_16795	COG4145	pantothenate transmembrane transporter activity
GSN03_16805	COG1012	belongs to the aldehyde dehydrogenase family
GSN03_16810	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_16820	COG1657	PFAM Prenyltransferase squalene oxidase
GSN03_16825	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GSN03_16830	COG2962	Rard protein
GSN03_16835	COG3326	Membrane
GSN03_16865	COG2226	methyltransferase
GSN03_16870	COG4166	transmembrane transport
GSN03_16875	COG4166	transmembrane transport
GSN03_16880	COG4166	transmembrane transport
GSN03_16885	COG1301	dicarboxylic acid transport
GSN03_16890	COG1316	TRANSCRIPTIONal
GSN03_16900	COG1595	DNA-templated transcription, initiation
GSN03_16915	COG1131	(ABC) transporter
GSN03_16925	COG2378	regulation of single-species biofilm formation
GSN03_16935	COG0673	inositol 2-dehydrogenase activity
GSN03_16940	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GSN03_16945	COG0187	DNA topoisomerase II activity
GSN03_16950	COG1832	CoA-binding protein
GSN03_16955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GSN03_16960	COG0745	RESPONSE REGULATOR receiver
GSN03_16980	COG4841	protein insertion into membrane
GSN03_16985	COG0824	Thioesterase
GSN03_17015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GSN03_17030	COG2274	protein secretion by the type I secretion system
GSN03_17035	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GSN03_17065	COG2211	Major facilitator Superfamily
GSN03_17075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GSN03_17090	COG0183	Belongs to the thiolase family
GSN03_17095	COG0318	PFAM AMP-dependent synthetase and ligase
GSN03_17100	COG1268	BioY protein
GSN03_17105	COG0318	PFAM AMP-dependent synthetase and ligase
GSN03_17120	COG1396	sequence-specific DNA binding
GSN03_17160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSN03_17170	COG5002	protein histidine kinase activity
GSN03_17180	COG0400	carboxylic ester hydrolase activity
GSN03_17185	COG0346	lactoylglutathione lyase activity
GSN03_17190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GSN03_17195	COG0069	glutamate synthase activity
GSN03_17200	COG1902	pentaerythritol trinitrate reductase activity
GSN03_17205	COG1329	Transcriptional regulator
GSN03_17210	COG0010	Belongs to the arginase family
GSN03_17235	COG2226	methyltransferase
GSN03_17270	COG4846	Membrane protein involved in cytochrome C biogenesis
GSN03_17275	COG0785	Cytochrome C biogenesis protein
GSN03_17285	COG1473	amidohydrolase
GSN03_17295	COG1131	(ABC) transporter
GSN03_17305	COG0583	DNA-binding transcription factor activity
GSN03_17315	COG1346	cytolysis
GSN03_17320	COG2816	NAD+ diphosphatase activity
GSN03_17330	COG0730	response to heat
GSN03_17340	COG3409	Peptidoglycan-binding domain 1 protein
GSN03_17340	COG5632	N-Acetylmuramoyl-L-alanine amidase
GSN03_17360	COG1132	(ABC) transporter
GSN03_17365	COG1132	(ABC) transporter
GSN03_17370	COG3763	UPF0154 protein
GSN03_17390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSN03_17410	COG1695	Transcriptional regulator
GSN03_17415	COG0174	glutamine synthetase
GSN03_17420	COG0789	Transcriptional regulator
GSN03_17425	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GSN03_17430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GSN03_17435	COG2860	membrane
GSN03_17440	COG0464	growth
GSN03_17470	COG1388	LysM domain
GSN03_17470	COG3584	3D domain protein
GSN03_17475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GSN03_17475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GSN03_17475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GSN03_17480	COG1105	Belongs to the carbohydrate kinase PfkB family
GSN03_17485	COG1349	DNA-binding transcription factor activity
GSN03_17490	COG1979	alcohol dehydrogenase
GSN03_17495	COG2322	membrane
GSN03_17505	COG1113	amino acid transport
GSN03_17510	COG1473	amidohydrolase
GSN03_17515	COG1408	metallophosphoesterase
GSN03_17520	COG2116	formate transmembrane transporter activity
GSN03_17535	COG2217	Heavy metal translocating P-type atpase
GSN03_17540	COG2608	mercury ion transmembrane transporter activity
GSN03_17545	COG1937	Protein conserved in bacteria
GSN03_17555	COG1230	cation diffusion facilitator family transporter
GSN03_17575	COG2819	hydrolase of the alpha beta superfamily
GSN03_17580	COG1120	ATPase activity
GSN03_17585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSN03_17590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSN03_17595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GSN03_17600	COG0708	Exodeoxyribonuclease III
GSN03_17605	COG2169	Transcriptional regulator
GSN03_17610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GSN03_17615	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GSN03_17620	COG2706	6-phosphogluconolactonase activity
GSN03_17625	COG2195	Cleaves the N-terminal amino acid of tripeptides
GSN03_17630	COG2364	Membrane
GSN03_17645	COG0346	lactoylglutathione lyase activity
GSN03_17650	COG5001	Diguanylate cyclase
GSN03_17650	COG3300	MHYT domain
GSN03_17690	COG1346	cytolysis
GSN03_17700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSN03_17705	COG0596	Alpha beta hydrolase
GSN03_17705	COG0508	dehydrogenase complex catalyzes the overall conversion of
GSN03_17710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GSN03_17720	COG2188	Transcriptional regulator
GSN03_17725	COG2723	6-phospho-beta-galactosidase activity
GSN03_17730	COG0840	transmembrane signaling receptor activity
GSN03_17740	COG1368	sulfuric ester hydrolase activity
GSN03_17745	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GSN03_17755	COG2723	6-phospho-beta-galactosidase activity
GSN03_17760	COG1263	PTS System
GSN03_17760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GSN03_17760	COG2190	(PTS) system
GSN03_17765	COG3711	transcriptional antiterminator
GSN03_17780	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GSN03_17785	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GSN03_17795	COG4550	Control of competence regulator ComK, YlbF/YmcA
GSN03_17800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GSN03_17805	COG1013	pyruvate-flavodoxin oxidoreductase activity
GSN03_17810	COG0674	pyruvate-flavodoxin oxidoreductase activity
GSN03_17810	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GSN03_17820	COG2359	stage V sporulation protein S
GSN03_17825	COG1692	metallophosphoesterase
GSN03_17840	COG1058	Belongs to the CinA family
GSN03_17840	COG1546	Belongs to the CinA family
GSN03_17845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GSN03_17850	COG1426	Protein conserved in bacteria
GSN03_17865	COG0300	oxidoreductase activity
GSN03_17870	COG0612	Peptidase, M16
GSN03_17875	COG0612	Peptidase, M16
GSN03_17880	COG1079	Belongs to the binding-protein-dependent transport system permease family
GSN03_17885	COG4603	Belongs to the binding-protein-dependent transport system permease family
GSN03_17890	COG3845	ABC transporter
GSN03_17895	COG1744	ABC transporter substrate-binding protein PnrA-like
GSN03_17900	COG2188	Transcriptional regulator
GSN03_17905	COG1674	ftsk spoiiie
GSN03_17915	COG0740	serine-type endopeptidase activity
GSN03_17920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GSN03_17930	COG0527	aspartate kinase activity
GSN03_17935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GSN03_17940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GSN03_17945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSN03_17950	COG1873	PFAM PRC-barrel domain
GSN03_17955	COG0612	Peptidase, M16
GSN03_17960	COG0726	polysaccharide deacetylase
GSN03_17975	COG0196	riboflavin kinase activity
GSN03_17990	COG1550	Protein conserved in bacteria
GSN03_18000	COG1358	cellular component organization or biogenesis
GSN03_18005	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GSN03_18010	COG0195	Participates in both transcription termination and antitermination
GSN03_18030	COG0750	zinc metalloprotease
GSN03_18040	COG4589	Belongs to the CDS family
GSN03_18060	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GSN03_18085	COG4974	Belongs to the 'phage' integrase family
GSN03_18095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GSN03_18100	COG0758	DNA mediated transformation
GSN03_18105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GSN03_18110	COG0045	succinate-CoA ligase (ADP-forming) activity
GSN03_18115	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GSN03_18130	COG0335	large ribosomal subunit rRNA binding
GSN03_18135	COG0336	Belongs to the RNA methyltransferase TrmD family
GSN03_18145	COG1837	Belongs to the UPF0109 family
GSN03_18155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GSN03_18165	COG0552	protein localization to endoplasmic reticulum
GSN03_18170	COG1196	nuclear chromosome segregation
GSN03_18180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GSN03_18185	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_18190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GSN03_18205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GSN03_18210	COG1461	Dihydroxyacetone kinase
GSN03_18215	COG1302	Protein conserved in bacteria
GSN03_18230	COG1564	THIamine pyrophosphokinase
GSN03_18235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GSN03_18240	COG1162	GTPase activity
GSN03_18245	COG0515	serine threonine protein kinase
GSN03_18245	COG2815	serine threonine protein kinase
GSN03_18250	COG0631	protein serine/threonine phosphatase activity
GSN03_18255	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GSN03_18260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GSN03_18260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GSN03_18265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GSN03_18275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GSN03_18280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GSN03_18300	COG1561	YicC-like family, N-terminal region
GSN03_18305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GSN03_18315	COG0006	proline dipeptidase activity
GSN03_18335	COG3069	C4-dicarboxylate transmembrane transporter activity
GSN03_18360	COG0543	2 iron, 2 sulfur cluster binding
GSN03_18395	COG0564	pseudouridine synthase activity
GSN03_18410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GSN03_18415	COG3599	regulation of cell shape
GSN03_18420	COG2302	S4 RNA-binding domain
GSN03_18425	COG0762	integral membrane protein
GSN03_18435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GSN03_18445	COG1873	PFAM PRC-barrel domain
GSN03_18450	COG1191	sigma factor activity
GSN03_18455	COG1191	sigma factor activity
GSN03_18465	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GSN03_18470	COG0849	cell division
GSN03_18475	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GSN03_18490	COG0772	Belongs to the SEDS family
GSN03_18495	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GSN03_18500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GSN03_18505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GSN03_18510	COG0768	penicillin binding
GSN03_18515	COG0768	penicillin binding
GSN03_18525	COG0275	rRNA processing
GSN03_18530	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GSN03_18535	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GSN03_18550	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GSN03_18555	COG1399	metal-binding, possibly nucleic acid-binding protein
GSN03_18560	COG1323	Belongs to the UPF0348 family
GSN03_18565	COG3480	Lon protease (S16) C-terminal proteolytic domain
GSN03_18570	COG1752	Esterase of the alpha-beta hydrolase superfamily
GSN03_18575	COG3314	Sporulation integral membrane protein YlbJ
GSN03_18585	COG0742	ribosomal rna small subunit methyltransferase
GSN03_18595	COG4471	UPF0298 protein
GSN03_18600	COG3679	Belongs to the UPF0342 family
GSN03_18605	COG0406	alpha-ribazole phosphatase activity
GSN03_18620	COG2340	Cysteine-rich secretory protein family
GSN03_18630	COG3336	cytochrome c oxidase
GSN03_18655	COG0109	protoheme IX farnesyltransferase activity
GSN03_18665	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GSN03_18670	COG0772	Belongs to the SEDS family
GSN03_18675	COG4838	Belongs to the UPF0358 family
GSN03_18680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GSN03_18685	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GSN03_18695	COG4896	Protein conserved in bacteria
GSN03_18710	COG1217	gtp-binding protein TYPA
GSN03_18720	COG0483	inositol monophosphate 1-phosphatase activity
GSN03_18730	COG4493	Belongs to the UPF0637 family
GSN03_18735	COG4476	Belongs to the UPF0223 family
GSN03_18740	COG1982	Orn Lys Arg decarboxylase major
GSN03_18790	COG0022	dehydrogenase e1 component
GSN03_18795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GSN03_18810	COG0561	phosphatase activity
GSN03_18815	COG5503	Protein of unknown function (DUF1447)
GSN03_18820	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GSN03_18825	COG0569	domain protein
GSN03_18835	COG1473	amidohydrolase
GSN03_18845	COG0583	DNA-binding transcription factor activity
GSN03_18850	COG0517	IMP dehydrogenase activity
GSN03_18860	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GSN03_18870	COG4703	Protein of unknown function (DUF1797)
GSN03_18885	COG2200	EAL domain
GSN03_18890	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_18895	COG1408	metallophosphoesterase
GSN03_18905	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GSN03_18940	COG2814	Major facilitator Superfamily
GSN03_18950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GSN03_18960	COG3209	COG3209 Rhs family protein
GSN03_18970	COG2205	protein histidine kinase activity
GSN03_18980	COG0436	Aminotransferase
GSN03_18985	COG1609	Transcriptional regulator
GSN03_18990	COG3833	ABC-type maltose transport systems, permease component
GSN03_18995	COG1175	transmembrane transport
GSN03_19000	COG2182	Extracellular solute-binding protein
GSN03_19010	COG0366	Alpha amylase catalytic
GSN03_19015	COG3842	ATPase activity
GSN03_19050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GSN03_19055	COG0183	Belongs to the thiolase family
GSN03_19090	COG1695	Transcriptional regulator
GSN03_19095	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_19115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GSN03_19120	COG0436	Aminotransferase
GSN03_19125	COG1850	ribulose-bisphosphate carboxylase activity
GSN03_19140	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GSN03_19155	COG2084	Dehydrogenase
GSN03_19165	COG2199	diguanylate cyclase activity
GSN03_19170	COG0778	Nitroreductase
GSN03_19195	COG1263	PTS System
GSN03_19195	COG2190	(PTS) system
GSN03_19195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GSN03_19200	COG3711	transcriptional antiterminator
GSN03_19210	COG2188	Transcriptional regulator
GSN03_19230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GSN03_19235	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GSN03_19245	COG1547	Domain of unknown function (DUF309)
GSN03_19255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GSN03_19260	COG4086	secreted protein
GSN03_19265	COG0561	phosphatase activity
GSN03_19270	COG0697	spore germination
GSN03_19285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GSN03_19310	COG0733	neurotransmitter:sodium symporter activity
GSN03_19330	COG1686	Belongs to the peptidase S11 family
GSN03_19335	COG1725	Transcriptional regulator
GSN03_19340	COG1131	(ABC) transporter
GSN03_19360	COG1846	Transcriptional regulator
GSN03_19375	COG0598	Magnesium transport protein CorA
GSN03_19400	COG4974	Belongs to the 'phage' integrase family
GSN03_19410	COG0735	belongs to the Fur family
GSN03_19415	COG1300	Membrane
GSN03_19435	COG0667	Aldo Keto reductase
GSN03_19440	COG0656	L-ascorbic acid biosynthetic process
GSN03_19445	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GSN03_19445	COG0456	acetyltransferase
GSN03_19455	COG0737	Belongs to the 5'-nucleotidase family
GSN03_19455	COG1525	nuclease
GSN03_19455	COG4085	toxin activity
GSN03_19460	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GSN03_19475	COG0596	Alpha beta hydrolase
GSN03_19480	COG2056	Na+-H+ antiporter family
GSN03_19485	COG1609	Transcriptional regulator
GSN03_19490	COG0456	acetyltransferase
GSN03_19495	COG1073	alpha beta
GSN03_19510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GSN03_19510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GSN03_19515	COG0307	riboflavin synthase, alpha
GSN03_19520	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GSN03_19520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GSN03_19535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GSN03_19540	COG4106	trans-aconitate 2-methyltransferase activity
GSN03_19545	COG1073	alpha beta
GSN03_19545	COG2226	methyltransferase
GSN03_19550	COG0156	8-amino-7-oxononanoate synthase activity
GSN03_19560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GSN03_19570	COG1757	Na H antiporter
GSN03_19575	COG0737	Belongs to the 5'-nucleotidase family
GSN03_19585	COG1522	sequence-specific DNA binding
GSN03_19610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GSN03_19630	COG0300	oxidoreductase activity
GSN03_19635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSN03_19640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GSN03_19645	COG1760	l-serine dehydratase
GSN03_19650	COG1760	l-serine dehydratase
GSN03_19680	COG2195	Cleaves the N-terminal amino acid of tripeptides
GSN03_19685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSN03_19700	COG1376	ErfK ybiS ycfS ynhG family protein
GSN03_19705	COG4129	membrane
GSN03_19710	COG1126	abc transporter atp-binding protein
GSN03_19715	COG0765	amino acid transport
GSN03_19720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSN03_19735	COG2816	NAD+ diphosphatase activity
GSN03_19740	COG2323	membrane
GSN03_19745	COG0772	Belongs to the SEDS family
GSN03_19750	COG0508	dehydrogenase complex catalyzes the overall conversion of
GSN03_19755	COG0022	dehydrogenase e1 component
GSN03_19760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GSN03_19765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GSN03_19780	COG0280	phosphate acetyltransferase
GSN03_19785	COG3290	protein histidine kinase activity
GSN03_19785	COG3829	transcription factor binding
GSN03_19795	COG0584	glycerophosphoryl diester phosphodiesterase
GSN03_19800	COG3093	addiction module antidote protein HigA
GSN03_19830	COG0745	RESPONSE REGULATOR receiver
GSN03_19835	COG0750	zinc metalloprotease
GSN03_19840	COG0497	DNA recombination
GSN03_19845	COG1438	arginine binding
GSN03_19850	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GSN03_19860	COG0142	geranyltranstransferase activity
GSN03_19865	COG1722	exodeoxyribonuclease VII activity
GSN03_19880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GSN03_19885	COG1302	Protein conserved in bacteria
GSN03_19890	COG0439	Biotin carboxylase
GSN03_19895	COG0511	ligase activity, forming carbon-carbon bonds
GSN03_19940	COG3854	ATPases associated with a variety of cellular activities
GSN03_19960	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GSN03_19965	COG0006	proline dipeptidase activity
GSN03_19980	COG3872	metal-dependent enzyme
GSN03_19990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSN03_20030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GSN03_20040	COG1609	Transcriptional regulator
GSN03_20050	COG2076	Multidrug Resistance protein
GSN03_20055	COG2076	Multidrug Resistance protein
GSN03_20095	COG1725	Transcriptional regulator
GSN03_20120	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GSN03_20125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GSN03_20155	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GSN03_20180	COG4970	Tfp pilus assembly protein FimT
GSN03_20195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GSN03_20250	COG0646	methionine synthase
GSN03_20250	COG1410	methionine synthase
GSN03_20255	COG0646	methionine synthase
GSN03_20255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GSN03_20260	COG0626	cystathionine gamma-synthase activity
GSN03_20265	COG0626	cystathionine gamma-synthase activity
GSN03_20285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSN03_20295	COG1940	carbohydrate kinase activity
GSN03_20300	COG4483	Protein conserved in bacteria
GSN03_20305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GSN03_20310	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GSN03_20315	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GSN03_20320	COG0704	Plays a role in the regulation of phosphate uptake
GSN03_20330	COG0581	inorganic phosphate transmembrane transporter activity
GSN03_20335	COG0573	inorganic phosphate transmembrane transporter activity
GSN03_20340	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GSN03_20345	COG0768	penicillin binding
GSN03_20350	COG0477	Major facilitator Superfamily
GSN03_20355	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GSN03_20380	COG0735	belongs to the Fur family
GSN03_20385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GSN03_20390	COG1121	(ABC) transporter
GSN03_20395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSN03_20425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GSN03_20430	COG2384	SAM-dependent methyltransferase
GSN03_20435	COG2010	Cytochrome c
GSN03_20440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GSN03_20445	COG0358	DNA primase activity
GSN03_20455	COG0517	IMP dehydrogenase activity
GSN03_20460	COG1381	Involved in DNA repair and RecF pathway recombination
GSN03_20470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GSN03_20475	COG0295	cytidine deaminase activity
GSN03_20480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GSN03_20485	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GSN03_20490	COG1480	7TM receptor with intracellular HD hydrolase
GSN03_20495	COG1702	phosphate starvation-inducible protein PhoH
GSN03_20510	COG1610	YqeY-like protein
GSN03_20515	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GSN03_20520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GSN03_20525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GSN03_20535	COG0484	heat shock protein binding
GSN03_20555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GSN03_20560	COG1733	regulation of RNA biosynthetic process
GSN03_20585	COG1466	dna polymerase III delta subunit
GSN03_20595	COG0658	competence protein
GSN03_20595	COG2333	competence protein COMEC
GSN03_20600	COG2131	deaminase
GSN03_20605	COG1555	photosystem II stabilization
GSN03_20605	COG1596	polysaccharide export
GSN03_20610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GSN03_20615	COG2226	methyltransferase
GSN03_20620	COG0799	negative regulation of ribosome biogenesis
GSN03_20625	COG1713	HD superfamily hydrolase involved in NAD metabolism
GSN03_20630	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GSN03_20635	COG1534	Rna-binding protein
GSN03_20640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GSN03_20645	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GSN03_20650	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GSN03_20660	COG0688	phosphatidylethanolamine metabolic process
GSN03_20670	COG2357	RelA SpoT domain protein
GSN03_20680	COG1785	Belongs to the alkaline phosphatase family
GSN03_20690	COG2267	carboxylic ester hydrolase activity
GSN03_20730	COG3186	Phenylalanine-4-hydroxylase
GSN03_20740	COG2514	catechol 2,3-dioxygenase activity
GSN03_20745	COG2259	Doxx family
GSN03_20785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GSN03_20795	COG1012	belongs to the aldehyde dehydrogenase family
GSN03_20795	COG1454	alcohol dehydrogenase
GSN03_20800	COG0626	cystathionine gamma-synthase activity
GSN03_20805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GSN03_20810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GSN03_20815	COG2226	methyltransferase
GSN03_20830	COG0768	penicillin binding
GSN03_20845	COG0826	peptidase U32
GSN03_20850	COG0826	peptidase U32
GSN03_20855	COG4122	O-methyltransferase activity
GSN03_20860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GSN03_20875	COG4472	Bacterial protein of unknown function (DUF965)
GSN03_20890	COG0628	permease
GSN03_20910	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GSN03_20925	COG1104	cysteine desulfurase activity
GSN03_20930	COG1959	2 iron, 2 sulfur cluster binding
GSN03_20935	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GSN03_20945	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GSN03_20970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GSN03_20975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GSN03_20980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GSN03_20980	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GSN03_20985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GSN03_20990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GSN03_20990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GSN03_21000	COG2244	polysaccharide biosynthetic process
GSN03_21005	COG2323	membrane
GSN03_21015	COG1862	Preprotein translocase
GSN03_21035	COG2255	four-way junction helicase activity
GSN03_21040	COG0632	four-way junction helicase activity
GSN03_21045	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GSN03_21070	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GSN03_21075	COG0157	Belongs to the NadC ModD family
GSN03_21080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GSN03_21085	COG1104	cysteine desulfurase activity
GSN03_21090	COG1827	regulation of RNA biosynthetic process
GSN03_21095	COG2258	MOSC domain
GSN03_21100	COG0077	Prephenate dehydratase
GSN03_21105	COG0577	efflux transmembrane transporter activity
GSN03_21110	COG0577	efflux transmembrane transporter activity
GSN03_21115	COG1136	(ABC) transporter
GSN03_21120	COG5002	protein histidine kinase activity
GSN03_21125	COG0745	RESPONSE REGULATOR receiver
GSN03_21130	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GSN03_21135	COG3290	protein histidine kinase activity
GSN03_21145	COG2868	ribosomal protein
GSN03_21155	COG1530	ribonuclease E activity
GSN03_21160	COG1994	Peptidase M50
GSN03_21165	COG0739	heme binding
GSN03_21170	COG2894	cell division
GSN03_21175	COG0850	regulation of cytokinetic process
GSN03_21190	COG1077	Cell shape determining protein MreB Mrl
GSN03_21195	COG2003	Belongs to the UPF0758 family
GSN03_21200	COG0424	maF-like protein
GSN03_21210	COG0285	dihydrofolate synthase activity
GSN03_21215	COG0525	valine-tRNA ligase activity
GSN03_21225	COG1388	LysM domain
GSN03_21235	COG0113	porphobilinogen synthase activity
GSN03_21240	COG1587	Uroporphyrinogen-III synthase
GSN03_21250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GSN03_21260	COG1846	Transcriptional regulator
GSN03_21265	COG1764	response to oxidative stress
GSN03_21270	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GSN03_21280	COG1067	ATP-dependent peptidase activity
GSN03_21280	COG0470	DNA polymerase III
GSN03_21290	COG0544	peptidyl-prolyl cis-trans isomerase activity
GSN03_21330	COG0622	Phosphoesterase
GSN03_21340	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GSN03_21345	COG5401	PFAM Sporulation and spore germination
GSN03_21365	COG1309	transcriptional regulator
GSN03_21375	COG2197	response regulator
GSN03_21380	COG2233	PERMEase
GSN03_21385	COG0402	S-adenosylhomocysteine deaminase activity
GSN03_21390	COG1983	PspC domain protein
GSN03_21395	COG1396	sequence-specific DNA binding
GSN03_21400	COG0697	spore germination
GSN03_21410	COG1959	2 iron, 2 sulfur cluster binding
GSN03_21415	COG1668	transmembrane transport
GSN03_21420	COG4152	abc transporter atp-binding protein
GSN03_21425	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GSN03_21435	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GSN03_21440	COG1876	peptidase activity
GSN03_21445	COG0824	Thioesterase
GSN03_21450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GSN03_21455	COG1053	succinate dehydrogenase
GSN03_21460	COG2009	succinate dehydrogenase
GSN03_21465	COG1719	4-vinyl reductase, 4VR
GSN03_21470	COG0322	excinuclease ABC activity
GSN03_21475	COG3118	belongs to the thioredoxin family
GSN03_21480	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GSN03_21485	COG2086	electron transfer activity
GSN03_21490	COG1024	Enoyl-CoA hydratase
GSN03_21495	COG1309	transcriptional regulator
GSN03_21500	COG0318	PFAM AMP-dependent synthetase and ligase
GSN03_21525	COG2318	DinB family
GSN03_21550	COG1131	(ABC) transporter
GSN03_21555	COG2205	protein histidine kinase activity
GSN03_21560	COG0745	RESPONSE REGULATOR receiver
GSN03_21565	COG4895	conserved protein (DUF2196)
GSN03_21570	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GSN03_21580	COG4509	Sortase family
GSN03_21585	COG1120	ATPase activity
GSN03_21600	COG5386	Cell surface protein
GSN03_21605	COG5386	Cell surface protein
GSN03_21610	COG1114	Component of the transport system for branched-chain amino acids
GSN03_21615	COG1187	pseudouridine synthase activity
GSN03_21625	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GSN03_21625	COG1796	DNA polymerase
GSN03_21630	COG1286	toxin biosynthetic process
GSN03_21675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GSN03_21685	COG1418	mRNA catabolic process
GSN03_21705	COG2814	Major facilitator Superfamily
GSN03_21710	COG1566	PFAM secretion protein HlyD family protein
GSN03_21715	COG1309	transcriptional regulator
GSN03_21720	COG1363	Peptidase, m42
GSN03_21745	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GSN03_21755	COG1484	DNA-dependent DNA replication
GSN03_21760	COG3611	Membrane attachment protein
GSN03_21765	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GSN03_21770	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GSN03_21775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GSN03_21785	COG1971	Probably functions as a manganese efflux pump
GSN03_21795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GSN03_21795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GSN03_21800	COG5002	protein histidine kinase activity
GSN03_21805	COG0745	RESPONSE REGULATOR receiver
GSN03_21825	COG0538	isocitrate dehydrogenase activity
GSN03_21830	COG0372	Belongs to the citrate synthase family
GSN03_21840	COG0628	permease
GSN03_21845	COG3030	protein affecting phage T7 exclusion by the F plasmid
GSN03_21855	COG0205	6-phosphofructokinase activity
GSN03_21870	COG1725	Transcriptional regulator
GSN03_21875	COG0281	malic enzyme
GSN03_21880	COG0587	DNA-directed DNA polymerase activity
GSN03_21895	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GSN03_21915	COG4109	DRTGG domain
GSN03_21925	COG0006	proline dipeptidase activity
GSN03_21965	COG0662	Cupin 2, conserved barrel domain protein
GSN03_21980	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_21985	COG0589	response to stress
GSN03_22025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSN03_22050	COG0827	DNA restriction-modification system
GSN03_22055	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GSN03_22060	COG3874	Sporulation protein YtfJ
GSN03_22075	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GSN03_22085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GSN03_22100	COG1104	cysteine desulfurase activity
GSN03_22105	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GSN03_22110	COG0583	DNA-binding transcription factor activity
GSN03_22115	COG0697	spore germination
GSN03_22120	COG1309	transcriptional regulator
GSN03_22125	COG1956	GAF domain-containing protein
GSN03_22135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GSN03_22160	COG1595	DNA-templated transcription, initiation
GSN03_22170	COG0110	maltose O-acetyltransferase activity
GSN03_22175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GSN03_22180	COG0454	-acetyltransferase
GSN03_22185	COG0517	IMP dehydrogenase activity
GSN03_22190	COG0123	including yeast histone deacetylase and acetoin utilization protein
GSN03_22205	COG0745	RESPONSE REGULATOR receiver
GSN03_22210	COG5002	protein histidine kinase activity
GSN03_22215	COG0666	response to abiotic stimulus
GSN03_22225	COG1970	mechanosensitive ion channel activity
GSN03_22250	COG1609	Transcriptional regulator
GSN03_22255	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GSN03_22255	COG1605	Chorismate mutase
GSN03_22260	COG4851	CamS sex pheromone cAM373 precursor
GSN03_22265	COG3118	belongs to the thioredoxin family
GSN03_22275	COG2309	aminopeptidase activity
GSN03_22295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSN03_22300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GSN03_22310	COG1674	ftsk spoiiie
GSN03_22325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GSN03_22330	COG4848	Belongs to the UPF0354 family
GSN03_22335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GSN03_22340	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GSN03_22345	COG1363	Peptidase, m42
GSN03_22355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSN03_22370	COG0510	thiamine kinase activity
GSN03_22375	COG1523	belongs to the glycosyl hydrolase 13 family
GSN03_22385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GSN03_22390	COG1349	DNA-binding transcription factor activity
GSN03_22395	COG1187	pseudouridine synthase activity
GSN03_22400	COG2244	polysaccharide biosynthetic process
GSN03_22405	COG2081	HI0933 family
GSN03_22410	COG2814	Major facilitator Superfamily
GSN03_22420	COG3832	glyoxalase III activity
GSN03_22440	COG1329	Transcriptional regulator
GSN03_22465	COG0314	molybdopterin synthase activity
GSN03_22470	COG1763	Mo-molybdopterin cofactor biosynthetic process
GSN03_22475	COG0303	'Molybdopterin
GSN03_22480	COG0315	cyclic pyranopterin monophosphate synthase activity
GSN03_22485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GSN03_22490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GSN03_22510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GSN03_22520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GSN03_22565	COG2814	Major facilitator Superfamily
GSN03_22570	COG0475	glutathione-regulated potassium exporter activity
GSN03_22575	COG0490	domain, Protein
GSN03_22580	COG0582	viral genome integration into host DNA
GSN03_22590	COG1136	(ABC) transporter
GSN03_22610	COG1242	4 iron, 4 sulfur cluster binding
GSN03_22615	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GSN03_22620	COG1131	(ABC) transporter
GSN03_22630	COG1794	racemase activity, acting on amino acids and derivatives
GSN03_22645	COG2267	carboxylic ester hydrolase activity
GSN03_22650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GSN03_22655	COG0671	phosphoesterase, PA-phosphatase related
GSN03_22660	COG0438	transferase activity, transferring glycosyl groups
GSN03_22685	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GSN03_22690	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GSN03_22725	COG5002	protein histidine kinase activity
GSN03_22730	COG3852	Histidine kinase
GSN03_22735	COG0753	catalase activity
GSN03_22740	COG2267	carboxylic ester hydrolase activity
GSN03_22755	COG1368	sulfuric ester hydrolase activity
GSN03_22765	COG4895	conserved protein (DUF2196)
GSN03_22785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSN03_22790	COG1116	anion transmembrane transporter activity
GSN03_22795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSN03_22820	COG0494	nUDIX hydrolase
GSN03_22855	COG1854	S-ribosylhomocysteine lyase activity
GSN03_22865	COG0288	reversible hydration of carbon dioxide
GSN03_22870	COG1271	oxidase subunit
GSN03_22875	COG1294	oxidase, subunit
GSN03_22890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSN03_22915	COG1842	Phage shock protein A
GSN03_22940	COG3859	Proton-coupled thiamine transporter YuaJ
GSN03_22945	COG5002	protein histidine kinase activity
GSN03_22950	COG0745	RESPONSE REGULATOR receiver
GSN03_22980	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GSN03_22985	COG1597	lipid kinase activity
GSN03_23025	COG0586	Pfam SNARE associated Golgi protein
GSN03_23035	COG0577	efflux transmembrane transporter activity
GSN03_23040	COG1136	(ABC) transporter
GSN03_23045	COG3708	Transcriptional regulator
GSN03_23045	COG2207	Transcriptional regulator
GSN03_23055	COG1131	(ABC) transporter
GSN03_23065	COG5658	integral membrane protein
GSN03_23070	COG0640	Transcriptional regulator
GSN03_23075	COG0745	RESPONSE REGULATOR receiver
GSN03_23080	COG2205	protein histidine kinase activity
GSN03_23085	COG0577	efflux transmembrane transporter activity
GSN03_23090	COG0577	efflux transmembrane transporter activity
GSN03_23095	COG1136	(ABC) transporter
GSN03_23100	COG0577	efflux transmembrane transporter activity
GSN03_23115	COG2188	Transcriptional regulator
GSN03_23135	COG3964	amidohydrolase
GSN03_23155	COG4948	Mandelate Racemase Muconate Lactonizing
GSN03_23165	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GSN03_23170	COG0596	Alpha beta hydrolase
GSN03_23175	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GSN03_23180	COG1169	isochorismate synthase
GSN03_23185	COG1575	Belongs to the MenA family. Type 1 subfamily
GSN03_23190	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GSN03_23195	COG1278	Cold shock
GSN03_23215	COG0058	SHG alpha-glucan phosphorylase activity
GSN03_23225	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GSN03_23230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GSN03_23235	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GSN03_23245	COG1404	Belongs to the peptidase S8 family
GSN03_23390	COG1285	pathogenesis
GSN03_23395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GSN03_23405	COG0166	Belongs to the GPI family
GSN03_23410	COG2155	Conserved Protein
GSN03_23415	COG1098	S1 RNA binding domain
GSN03_23420	COG0436	Aminotransferase
GSN03_23425	COG1522	sequence-specific DNA binding
GSN03_23430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSN03_23435	COG2267	carboxylic ester hydrolase activity
GSN03_23445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GSN03_23460	COG5018	Exonuclease
GSN03_23465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GSN03_23485	COG2050	protein possibly involved in aromatic compounds catabolism
GSN03_23495	COG1268	BioY protein
GSN03_23500	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GSN03_23505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GSN03_23515	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GSN03_23520	COG3584	3D domain protein
GSN03_23535	COG1252	NADH dehydrogenase
GSN03_23545	COG3708	Transcriptional regulator
GSN03_23555	COG1683	Conserved Protein
GSN03_23565	COG4122	O-methyltransferase activity
GSN03_23575	COG0316	Belongs to the HesB IscA family
GSN03_23580	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GSN03_23590	COG1252	NADH dehydrogenase
GSN03_23600	COG2274	protein secretion by the type I secretion system
GSN03_23605	COG0390	transport system, permease component
GSN03_23610	COG2824	Alkylphosphonate utilization operon protein PhnA
GSN03_23660	COG4837	Protein of unknown function (DUF1462)
GSN03_23665	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GSN03_23675	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GSN03_23680	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GSN03_23695	COG0577	efflux transmembrane transporter activity
GSN03_23695	COG1136	(ABC) transporter
GSN03_23700	COG2249	NAD(P)H dehydrogenase (quinone) activity
GSN03_23710	COG0647	UMP catabolic process
GSN03_23720	COG2445	Protein of unknown function DUF86
GSN03_23725	COG1494	fructose-1,6-bisphosphatase
GSN03_23745	COG4470	Protein conserved in bacteria
GSN03_23755	COG0789	Transcriptional regulator
GSN03_23760	COG4377	Putative membrane peptidase family (DUF2324)
GSN03_23785	COG0739	heme binding
GSN03_23795	COG3377	Domain of unknown function (DUF1805)
GSN03_23800	COG0737	Belongs to the 5'-nucleotidase family
GSN03_23805	COG1695	Transcriptional regulator
GSN03_23815	COG0719	Fe-S assembly protein
GSN03_23820	COG0822	iron-sulfur transferase activity
GSN03_23825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GSN03_23830	COG0719	Fe-S assembly protein
GSN03_23835	COG0396	ATPase activity
GSN03_23840	COG1464	Belongs to the NlpA lipoprotein family
GSN03_23845	COG1464	Belongs to the NlpA lipoprotein family
GSN03_23850	COG2011	ABC-type metal ion transport system permease component
GSN03_23865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GSN03_23870	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GSN03_23875	COG0509	glycine decarboxylation via glycine cleavage system
GSN03_23880	COG1393	Belongs to the ArsC family
GSN03_23925	COG1309	transcriptional regulator
GSN03_23930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSN03_23935	COG1960	acyl-CoA dehydrogenase activity
GSN03_23940	COG0183	Belongs to the thiolase family
GSN03_23945	COG1024	Enoyl-CoA hydratase
GSN03_23945	COG1250	3-hydroxyacyl-CoA dehydrogenase
GSN03_23955	COG1686	Belongs to the peptidase S11 family
GSN03_23970	COG0011	TIGRFAM Protein of
GSN03_23990	COG2814	Major facilitator Superfamily
GSN03_23995	COG0531	amino acid
GSN03_24015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GSN03_24050	COG0586	Pfam SNARE associated Golgi protein
GSN03_24060	COG1376	ErfK ybiS ycfS ynhG family protein
GSN03_24065	COG0745	RESPONSE REGULATOR receiver
GSN03_24070	COG5002	protein histidine kinase activity
GSN03_24080	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GSN03_24090	COG2151	metal-sulfur cluster biosynthetic enzyme
GSN03_24095	COG3227	Zinc metalloprotease (Elastase)
GSN03_24115	COG0586	Pfam SNARE associated Golgi protein
GSN03_24120	COG0475	glutathione-regulated potassium exporter activity
GSN03_24125	COG0490	domain, Protein
GSN03_24130	COG1115	amino acid carrier protein
GSN03_24135	COG0783	Belongs to the Dps family
GSN03_24145	COG2318	DinB family
GSN03_24155	COG1611	Belongs to the LOG family
GSN03_24165	COG1528	Iron-storage protein
GSN03_24170	COG2311	Membrane
GSN03_24175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GSN03_24180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GSN03_24185	COG1115	amino acid carrier protein
GSN03_24190	COG2910	NAD(P)H-binding
GSN03_24200	COG0656	L-ascorbic acid biosynthetic process
GSN03_24205	COG2814	Major facilitator Superfamily
GSN03_24210	COG1733	regulation of RNA biosynthetic process
GSN03_24220	COG1252	NADH dehydrogenase
GSN03_24245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GSN03_24265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSN03_24275	COG1733	regulation of RNA biosynthetic process
GSN03_24280	COG0778	Nitroreductase
GSN03_24285	COG4224	UPF0291 protein
GSN03_24290	COG1335	isochorismatase
GSN03_24295	COG1522	sequence-specific DNA binding
GSN03_24305	COG1522	sequence-specific DNA binding
GSN03_24310	COG0288	reversible hydration of carbon dioxide
GSN03_24315	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GSN03_24320	COG2233	PERMEase
GSN03_24365	COG0557	exoribonuclease II activity
GSN03_24370	COG1647	Serine aminopeptidase, S33
GSN03_24375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GSN03_24380	COG1346	cytolysis
GSN03_24415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GSN03_24430	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GSN03_24455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GSN03_24470	COG2323	membrane
GSN03_24480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GSN03_24490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GSN03_24495	COG1660	Displays ATPase and GTPase activities
GSN03_24500	COG1051	belongs to the nudix hydrolase family
GSN03_24510	COG0492	ferredoxin-NADP+ reductase activity
GSN03_24515	COG0457	Tetratricopeptide repeat
GSN03_24520	COG0110	maltose O-acetyltransferase activity
GSN03_24525	COG0546	phosphoglycolate phosphatase activity
GSN03_24530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GSN03_24535	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GSN03_24540	COG1950	PFAM Membrane protein of
GSN03_24545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GSN03_24565	COG0789	Transcriptional regulator
GSN03_24595	COG0583	DNA-binding transcription factor activity
GSN03_24600	COG0789	Transcriptional regulator
GSN03_24605	COG0655	NAD(P)H dehydrogenase (quinone) activity
GSN03_24610	COG0488	(ABC) transporter
GSN03_24620	COG1132	(ABC) transporter
GSN03_24625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GSN03_24630	COG3409	Peptidoglycan-binding domain 1 protein
GSN03_24630	COG0793	Belongs to the peptidase S41A family
GSN03_24635	COG2177	Part of the ABC transporter FtsEX involved in
GSN03_24640	COG2884	Cell division ATP-binding protein ftsE
GSN03_24670	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GSN03_24675	COG1278	Cold shock
GSN03_24680	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GSN03_24685	COG1388	LysM domain
GSN03_24685	COG0791	NLP P60 protein
GSN03_24690	COG1733	regulation of RNA biosynthetic process
GSN03_24695	COG1307	EDD domain protein, DegV family
GSN03_24700	COG1739	Uncharacterized protein family UPF0029
GSN03_24705	COG1316	TRANSCRIPTIONal
GSN03_24710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GSN03_24715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GSN03_24720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GSN03_24730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GSN03_24730	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GSN03_24750	COG1486	melibiose metabolic process
GSN03_24755	COG1447	Phosphotransferase system cellobiose-specific component IIA
GSN03_24760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GSN03_24780	COG1447	Phosphotransferase system cellobiose-specific component IIA
GSN03_24790	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GSN03_24795	COG1301	dicarboxylic acid transport
GSN03_24810	COG1511	domain protein
GSN03_24815	COG0583	DNA-binding transcription factor activity
GSN03_24820	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GSN03_24825	COG1271	oxidase subunit
GSN03_24830	COG1294	oxidase, subunit
GSN03_24835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GSN03_24845	COG1620	l-lactate permease
GSN03_24855	COG2389	metal-binding protein
GSN03_24865	COG1368	sulfuric ester hydrolase activity
GSN03_24875	COG1388	LysM domain
GSN03_24875	COG0791	NLP P60 protein
GSN03_24880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GSN03_24890	COG1215	transferase activity, transferring glycosyl groups
GSN03_24895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GSN03_24900	COG1388	LysM domain
GSN03_24900	COG3584	3D domain protein
GSN03_24920	COG4715	Zinc finger, swim domain protein
GSN03_24925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GSN03_24980	COG0577	efflux transmembrane transporter activity
GSN03_24985	COG1136	(ABC) transporter
GSN03_25010	COG3850	Histidine kinase
GSN03_25010	COG5002	protein histidine kinase activity
GSN03_25015	COG0745	RESPONSE REGULATOR receiver
GSN03_25020	COG1316	TRANSCRIPTIONal
GSN03_25025	COG3764	Sortase (surface protein transpeptidase)
GSN03_25035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GSN03_25050	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GSN03_25070	COG0438	transferase activity, transferring glycosyl groups
GSN03_25085	COG1215	transferase activity, transferring glycosyl groups
GSN03_25090	COG1045	serine acetyltransferase
GSN03_25095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GSN03_25100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GSN03_25105	COG1086	Polysaccharide biosynthesis protein
GSN03_25110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GSN03_25115	COG4464	protein tyrosine phosphatase activity
GSN03_25120	COG0489	protein tyrosine kinase activity
GSN03_25125	COG3944	biosynthesis protein
GSN03_25135	COG1132	(ABC) transporter
GSN03_25165	COG0367	asparagine synthase
GSN03_25170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GSN03_25180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GSN03_25190	COG1216	Glycosyl transferase, family 2
GSN03_25225	COG1215	transferase activity, transferring glycosyl groups
GSN03_25245	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GSN03_25245	COG0463	Glycosyl transferase, family 2
GSN03_25255	COG0438	transferase activity, transferring glycosyl groups
GSN03_25260	COG0438	transferase activity, transferring glycosyl groups
GSN03_25265	COG1086	Polysaccharide biosynthesis protein
GSN03_25270	COG0489	protein tyrosine kinase activity
GSN03_25275	COG3944	biosynthesis protein
GSN03_25295	COG1609	Transcriptional regulator
GSN03_25305	COG0739	heme binding
GSN03_25320	COG3279	Response regulator of the LytR AlgR family
GSN03_25325	COG0318	PFAM AMP-dependent synthetase and ligase
GSN03_25330	COG2385	sporulation resulting in formation of a cellular spore
GSN03_25345	COG4836	Membrane
GSN03_25350	COG1007	ATP synthesis coupled electron transport
GSN03_25355	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GSN03_25360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GSN03_25365	COG0713	ATP synthesis coupled electron transport
GSN03_25370	COG0839	Belongs to the complex I subunit 6 family
GSN03_25380	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GSN03_25385	COG0649	NAD binding
GSN03_25390	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GSN03_25395	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GSN03_25400	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GSN03_25405	COG5001	Diguanylate cyclase
GSN03_25405	COG3300	MHYT domain
GSN03_25420	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GSN03_25425	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GSN03_25435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GSN03_25455	COG0356	it plays a direct role in the translocation of protons across the membrane
GSN03_25490	COG0698	ribose 5-phosphate isomerase
GSN03_25500	COG2190	(PTS) system
GSN03_25505	COG2259	Doxx family
GSN03_25510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GSN03_25520	COG1971	Probably functions as a manganese efflux pump
GSN03_25525	COG0009	L-threonylcarbamoyladenylate synthase
GSN03_25540	COG2890	protein-(glutamine-N5) methyltransferase activity
GSN03_25545	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GSN03_25550	COG1435	thymidine kinase activity
GSN03_25560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GSN03_25565	COG1494	fructose-1,6-bisphosphatase
GSN03_25585	COG4821	SIS domain
GSN03_25590	COG0504	CTP synthase activity
GSN03_25605	COG1960	acyl-CoA dehydrogenase activity
GSN03_25610	COG1960	acyl-CoA dehydrogenase activity
GSN03_25615	COG1250	3-hydroxyacyl-CoA dehydrogenase
GSN03_25620	COG0183	Belongs to the thiolase family
GSN03_25625	COG0247	lactate metabolic process
GSN03_25625	COG2181	nitrate reductase activity
GSN03_25630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GSN03_25635	COG4294	response to UV
GSN03_25640	COG5001	Diguanylate cyclase
GSN03_25640	COG3300	MHYT domain
GSN03_25660	COG2197	response regulator
GSN03_25665	COG4585	Histidine kinase
GSN03_25670	COG0842	Transport permease protein
GSN03_25675	COG1131	(ABC) transporter
GSN03_25680	COG0024	Methionine aminopeptidase
GSN03_25685	COG2234	aminopeptidase activity
GSN03_25700	COG4506	Protein conserved in bacteria
GSN03_25705	COG1619	proteins homologs of microcin C7 resistance protein MccF
GSN03_25720	COG0010	Belongs to the arginase family
GSN03_25730	COG2814	Major facilitator Superfamily
GSN03_25735	COG0789	Transcriptional regulator
GSN03_25740	COG0584	glycerophosphoryl diester phosphodiesterase
GSN03_25745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GSN03_25755	COG1994	Peptidase M50
GSN03_25765	COG1078	dGTPase activity
GSN03_25770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GSN03_25775	COG1120	ATPase activity
GSN03_25780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSN03_25785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSN03_25790	COG4844	belongs to the
GSN03_25805	COG0280	phosphate acetyltransferase
GSN03_25810	COG3253	May function as heme-dependent peroxidase
GSN03_25820	COG3773	Cell wall hydrolase
GSN03_25830	COG2363	Small membrane protein
GSN03_25840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GSN03_25845	COG2233	PERMEase
GSN03_25850	COG0561	phosphatase activity
GSN03_25855	COG2814	Major facilitator Superfamily
GSN03_25860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GSN03_25865	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GSN03_25870	COG1131	(ABC) transporter
GSN03_25875	COG2755	lipolytic protein G-D-S-L family
GSN03_25880	COG1609	Transcriptional regulator
GSN03_25890	COG0460	homoserine dehydrogenase
GSN03_25895	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GSN03_25900	COG2873	o-acetylhomoserine
GSN03_25910	COG1011	Hydrolase
GSN03_25915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GSN03_25925	COG2197	response regulator
GSN03_25930	COG2203	Gaf domain
GSN03_25930	COG4585	Histidine kinase
GSN03_25935	COG0351	phosphomethylpyrimidine kinase
GSN03_25940	COG3706	GGDEF domain
GSN03_25945	COG2879	small protein
GSN03_25950	COG1966	Carbon starvation protein
GSN03_25955	COG3279	Response regulator of the LytR AlgR family
GSN03_25960	COG0477	Major facilitator Superfamily
GSN03_25990	COG1607	acyl-coa hydrolase
GSN03_25995	COG1216	Glycosyl transferase, family 2
GSN03_26005	COG1216	Glycosyl transferase, family 2
GSN03_26015	COG0488	(ABC) transporter
GSN03_26020	COG1696	Membrane protein involved in D-alanine export
GSN03_26030	COG1309	transcriptional regulator
GSN03_26035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GSN03_26040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GSN03_26040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GSN03_26045	COG0628	permease
GSN03_26055	COG1380	Effector of murein hydrolase LrgA
GSN03_26060	COG3279	Response regulator of the LytR AlgR family
GSN03_26065	COG3275	phosphorelay sensor kinase activity
GSN03_26070	COG2814	Major facilitator Superfamily
GSN03_26075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GSN03_26080	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GSN03_26095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GSN03_26100	COG1272	protein, Hemolysin III
GSN03_26125	COG1164	Oligoendopeptidase f
GSN03_26135	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GSN03_26145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GSN03_26150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GSN03_26155	COG4853	Protein conserved in bacteria
GSN03_26165	COG5002	protein histidine kinase activity
GSN03_26170	COG0745	RESPONSE REGULATOR receiver
GSN03_26200	COG0305	Participates in initiation and elongation during chromosome replication
GSN03_26210	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GSN03_26215	COG4241	membrane
GSN03_26225	COG0629	single-stranded DNA binding
GSN03_26230	COG0360	Binds together with S18 to 16S ribosomal RNA
GSN03_26235	COG0012	GTP binding
GSN03_26240	COG4481	Protein conserved in bacteria
GSN03_26245	COG0668	transmembrane transport
GSN03_26255	COG1475	DNA binding
GSN03_26260	COG1192	Involved in chromosome partitioning
GSN03_26275	COG0445	tRNA wobble uridine modification
GSN03_26285	COG1847	R3H domain protein
GSN03_26290	COG0706	membrane insertase activity
GSN03_26295	COG0594	ribonuclease P activity
GSN03_26300	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GSN03_26340	COG2197	response regulator
GSN03_26350	COG2226	methyltransferase
GSN03_26355	COG5002	protein histidine kinase activity
GSN03_26385	COG2186	Transcriptional regulator
GSN03_26425	COG3344	reverse transcriptase
GSN03_26430	COG0791	NLP P60 protein
GSN03_26430	COG3883	PFAM NLP P60 protein
GSN03_26480	COG0814	amino acid
GSN03_26485	COG0697	spore germination
GSN03_26525	COG2211	Major facilitator Superfamily
GSN03_26570	COG0756	dUTP diphosphatase activity
GSN03_26685	COG2333	competence protein COMEC
GSN03_26685	COG0658	competence protein
GSN03_26690	COG1309	transcriptional regulator
GSN03_26700	COG2329	Antibiotic biosynthesis monooxygenase
GSN03_26730	COG3754	Rhamnan synthesis protein F
GSN03_26740	COG3754	Rhamnan synthesis protein F
GSN03_26760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GSN03_26770	COG2707	UPF0756 membrane protein
GSN03_26775	COG0596	Alpha beta hydrolase
GSN03_26780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GSN03_26795	COG4977	sequence-specific DNA binding
GSN03_26835	COG0741	lytic transglycosylase activity
GSN03_26910	COG2755	lipolytic protein G-D-S-L family
GSN03_26910	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GSN03_26935	COG1073	alpha beta
GSN03_26970	COG4974	Belongs to the 'phage' integrase family
GSN03_26990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GSN03_27000	COG1012	belongs to the aldehyde dehydrogenase family
GSN03_27020	COG1522	sequence-specific DNA binding
GSN03_27060	COG2267	carboxylic ester hydrolase activity
GSN03_27065	COG1335	isochorismatase
GSN03_27090	COG0583	DNA-binding transcription factor activity
GSN03_27095	COG1846	Transcriptional regulator
GSN03_27125	COG3227	Zinc metalloprotease (Elastase)
GSN03_27130	COG2373	Large extracellular alpha-helical protein
GSN03_27135	COG5632	N-Acetylmuramoyl-L-alanine amidase
GSN03_27135	COG3409	Peptidoglycan-binding domain 1 protein
GSN03_27165	COG2312	Erythromycin esterase
GSN03_27175	COG0739	heme binding
GSN03_27175	COG0741	lytic transglycosylase activity
GSN03_27175	COG1196	nuclear chromosome segregation
GSN03_27190	COG1028	Short-chain dehydrogenase reductase Sdr
GSN03_27245	COG1288	antiporter activity
GSN03_27250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GSN03_27300	COG3718	enzyme involved in inositol metabolism
GSN03_27315	COG0494	nUDIX hydrolase
GSN03_27335	COG0833	amino acid
GSN03_27340	COG2040	homocysteine
GSN03_27345	COG2002	toxin-antitoxin pair type II binding
GSN03_27350	COG0534	Mate efflux family protein
GSN03_27360	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GSN03_27400	COG1136	(ABC) transporter
GSN03_27405	COG0577	efflux transmembrane transporter activity
GSN03_27410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GSN03_27415	COG0745	RESPONSE REGULATOR receiver
GSN03_27420	COG5002	protein histidine kinase activity
GSN03_27425	COG0741	lytic transglycosylase activity
GSN03_27450	COG2755	lipolytic protein G-D-S-L family
GSN03_27450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GSN03_27490	COG0814	amino acid
GSN03_27495	COG1760	l-serine dehydratase
GSN03_27500	COG1760	l-serine dehydratase
GSN03_27510	COG1674	ftsk spoiiie
GSN03_27525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GSN03_27545	COG0583	DNA-binding transcription factor activity
GSN03_27550	COG0346	lactoylglutathione lyase activity
GSN03_27580	COG0463	Glycosyl transferase, family 2
GSN03_27595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSN03_27620	COG1999	signal sequence binding
GSN03_27625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GSN03_27630	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GSN03_27670	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GSN03_27705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GSN03_27720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSN03_27815	COG0745	RESPONSE REGULATOR receiver
GSN03_27860	COG0582	viral genome integration into host DNA
GSN03_27885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins