locus-tag	class	description
A361_00010	COG0592	DNA-directed DNA polymerase activity
A361_00015	COG2501	S4 domain
A361_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A361_00030	COG0187	DNA topoisomerase II activity
A361_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A361_00080	COG0516	GMP reductase activity
A361_00080	COG0517	IMP dehydrogenase activity
A361_00095	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A361_00100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A361_00115	COG1428	Deoxynucleoside kinase
A361_00120	COG1428	Deoxynucleoside kinase
A361_00125	COG3858	chitin binding
A361_00125	COG1388	LysM domain
A361_00130	COG1335	isochorismatase
A361_00135	COG0590	tRNA wobble adenosine to inosine editing
A361_00145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A361_00155	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A361_00200	COG1982	Orn Lys Arg decarboxylase major
A361_00205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A361_00210	COG3870	Protein conserved in bacteria
A361_00215	COG1728	Protein conserved in bacteria
A361_00220	COG0470	DNA polymerase III
A361_00225	COG1774	PSP1 C-terminal conserved region
A361_00230	COG4467	Involved in initiation control of chromosome replication
A361_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A361_00240	COG2827	Endonuclease containing a URI domain
A361_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A361_00250	COG2002	toxin-antitoxin pair type II binding
A361_00260	COG0084	hydrolase, TatD family'
A361_00270	COG3583	domain protein
A361_00270	COG3584	3D domain protein
A361_00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A361_00290	COG4466	Protein conserved in bacteria
A361_00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A361_00310	COG0251	oxidation-reduction process
A361_00320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A361_00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A361_00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A361_00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A361_00350	COG2002	toxin-antitoxin pair type II binding
A361_00355	COG2244	polysaccharide biosynthetic process
A361_00360	COG3956	TIGRFAM MazG family protein
A361_00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A361_00385	COG1098	S1 RNA binding domain
A361_00400	COG2208	phosphoserine phosphatase activity
A361_00405	COG2304	oxidoreductase activity
A361_00410	COG0515	serine threonine protein kinase
A361_00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A361_00430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
A361_00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
A361_00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A361_00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A361_00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A361_00455	COG0512	Glutamine amidotransferase of anthranilate synthase
A361_00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A361_00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A361_00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A361_00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A361_00480	COG1396	sequence-specific DNA binding
A361_00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A361_00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A361_00580	COG3880	PFAM UvrB UvrC protein
A361_00585	COG3869	Catalyzes the specific phosphorylation of arginine residues in
A361_00590	COG0542	response to heat
A361_00595	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A361_00605	COG4956	integral membrane protein (PIN domain superfamily)
A361_00610	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A361_00620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A361_00625	COG1045	serine acetyltransferase
A361_00630	COG0215	cysteine-tRNA ligase activity
A361_00640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A361_00645	COG3688	RNA-binding protein containing a PIN domain
A361_00655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A361_00660	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A361_00665	COG0250	Participates in transcription elongation, termination and antitermination
A361_00675	COG0081	regulation of translation
A361_00680	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A361_00690	COG2813	Specifically methylates the guanine in position
A361_00695	COG0085	RNA polymerase activity
A361_00700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A361_00705	COG1358	cellular component organization or biogenesis
A361_00710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A361_00730	COG0051	transcription antitermination factor activity, RNA binding
A361_00740	COG0088	Forms part of the polypeptide exit tunnel
A361_00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A361_00755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A361_00760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A361_00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A361_00770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A361_00775	COG0255	Belongs to the universal ribosomal protein uL29 family
A361_00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A361_00790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A361_00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A361_00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A361_00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A361_00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A361_00825	COG1841	ribosomal large subunit assembly
A361_00835	COG0201	protein transport
A361_00840	COG0563	adenylate kinase activity
A361_00845	COG0024	Methionine aminopeptidase
A361_00850	COG2163	COG2163 Ribosomal protein L14E L6E L27E
A361_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A361_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A361_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A361_00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A361_00875	COG0202	RNA polymerase activity
A361_00880	COG0203	ribosomal protein L17
A361_00885	COG1122	ATPase activity
A361_00890	COG1122	ATPase activity
A361_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A361_00900	COG0101	tRNA pseudouridine synthase activity
A361_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A361_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A361_00915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A361_00920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A361_00925	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A361_00935	COG0860	N-Acetylmuramoyl-L-alanine amidase
A361_00940	COG0489	protein tyrosine kinase activity
A361_00950	COG2194	sulfuric ester hydrolase activity
A361_00955	COG0726	polysaccharide deacetylase
A361_01035	COG1595	DNA-templated transcription, initiation
A361_01040	COG5662	AntiSigma factor
A361_01045	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A361_01050	COG4856	YbbR-like protein
A361_01055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A361_01060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A361_01070	COG1204	response to ionizing radiation
A361_01115	COG2801	Transposase and inactivated derivatives
A361_01125	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A361_01130	COG4605	iron ion homeostasis
A361_01135	COG4604	ABC transporter, ATP-binding protein
A361_01140	COG4607	ABC-type enterochelin transport system periplasmic component
A361_01155	COG1309	transcriptional regulator
A361_01160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A361_01185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A361_01195	COG2362	D-Aminopeptidase
A361_01200	COG0601	transmembrane transport
A361_01205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A361_01210	COG0444	Belongs to the ABC transporter superfamily
A361_01215	COG4166	transmembrane transport
A361_01220	COG1619	proteins homologs of microcin C7 resistance protein MccF
A361_01225	COG4948	Mandelate Racemase Muconate Lactonizing
A361_01230	COG0791	NLP P60 protein
A361_01235	COG4608	Belongs to the ABC transporter superfamily
A361_01245	COG3403	YqcI/YcgG family
A361_01260	COG0783	Belongs to the Dps family
A361_01265	COG0730	response to heat
A361_01270	COG0018	arginyl-trna synthetase
A361_01275	COG0772	Belongs to the SEDS family
A361_01285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A361_01290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A361_01295	COG1120	ATPase activity
A361_01300	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A361_01315	COG1492	cobalamin metabolic process
A361_01320	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A361_01335	COG2096	Adenosyltransferase
A361_01350	COG0406	alpha-ribazole phosphatase activity
A361_01365	COG0346	lactoylglutathione lyase activity
A361_01370	COG0659	secondary active sulfate transmembrane transporter activity
A361_01380	COG1301	dicarboxylic acid transport
A361_01385	COG1181	Belongs to the D-alanine--D-alanine ligase family
A361_01390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A361_01400	COG0513	Belongs to the DEAD box helicase family
A361_01405	COG4294	response to UV
A361_01410	COG3402	PFAM membrane-flanked domain
A361_01415	COG3428	Bacterial PH domain
A361_01420	COG0705	Rhomboid family
A361_01425	COG0736	holo-[acyl-carrier-protein] synthase activity
A361_01430	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A361_01440	COG0864	Transcriptional regulator
A361_01445	COG2337	Toxic component of a toxin-antitoxin (TA) module
A361_01450	COG1366	Belongs to the anti-sigma-factor antagonist family
A361_01455	COG1366	Belongs to the anti-sigma-factor antagonist family
A361_01460	COG2172	sigma factor antagonist activity
A361_01465	COG2208	phosphoserine phosphatase activity
A361_01475	COG2172	sigma factor antagonist activity
A361_01480	COG1191	sigma factor activity
A361_01485	COG2208	phosphoserine phosphatase activity
A361_01490	COG2183	response to ionizing radiation
A361_01495	COG3091	SprT-like family
A361_01580	COG0802	atpase or kinase
A361_01585	COG1214	PFAM Peptidase M22, glycoprotease
A361_01590	COG0456	acetyltransferase
A361_01600	COG0488	(ABC) transporter
A361_01605	COG0315	cyclic pyranopterin monophosphate synthase activity
A361_01610	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
A361_01620	COG1266	CAAX protease self-immunity
A361_01625	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A361_01695	COG2323	membrane
A361_01705	COG4842	Belongs to the WXG100 family
A361_01710	COG5417	Belongs to the EsaB family
A361_01715	COG4499	WXG100 protein secretion system (Wss), protein YukC
A361_01720	COG1674	ftsk spoiiie
A361_01720	COG0433	COG0433 Predicted ATPase
A361_01725	COG1511	domain protein
A361_01790	COG0714	Associated with various cellular activities
A361_01795	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A361_01800	COG1305	Transglutaminase-like
A361_01805	COG0519	Catalyzes the synthesis of GMP from XMP
A361_01805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A361_01810	COG2252	PERMEase
A361_01815	COG3711	transcriptional antiterminator
A361_01820	COG2190	(PTS) system
A361_01820	COG1263	PTS System
A361_01820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A361_01840	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
A361_01850	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A361_01855	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A361_01860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A361_01870	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A361_01875	COG0047	phosphoribosylformylglycinamidine synthase activity
A361_01885	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A361_01890	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A361_01895	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A361_01900	COG0138	bifunctional purine biosynthesis protein purh
A361_01905	COG0151	Belongs to the GarS family
A361_01920	COG1470	cell adhesion involved in biofilm formation
A361_01925	COG4496	protein, YerC YecD
A361_01930	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A361_01935	COG0210	DNA helicase
A361_01940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A361_01945	COG4851	CamS sex pheromone cAM373 precursor
A361_01950	COG1012	belongs to the aldehyde dehydrogenase family
A361_01955	COG1335	isochorismatase
A361_01965	COG2224	Isocitrate lyase
A361_01970	COG5506	Protein of unknown function (DUF1694)
A361_01985	COG0154	amidase activity
A361_01990	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A361_01995	COG3279	Response regulator of the LytR AlgR family
A361_02020	COG1227	inorganic diphosphatase activity
A361_02030	COG2202	Pas domain
A361_02030	COG1366	Belongs to the anti-sigma-factor antagonist family
A361_02035	COG2323	membrane
A361_02040	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A361_02055	COG1309	transcriptional regulator
A361_02060	COG1597	lipid kinase activity
A361_02070	COG5002	protein histidine kinase activity
A361_02085	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
A361_02090	COG3853	Toxic anion resistance protein (TelA)
A361_02095	COG5002	protein histidine kinase activity
A361_02100	COG0166	Belongs to the GPI family
A361_02105	COG0492	ferredoxin-NADP+ reductase activity
A361_02110	COG2234	aminopeptidase activity
A361_02115	COG0697	spore germination
A361_02120	COG2323	membrane
A361_02135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A361_02140	COG2310	stress, protein
A361_02145	COG0584	glycerophosphoryl diester phosphodiesterase
A361_02160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A361_02170	COG2814	Major facilitator Superfamily
A361_02185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A361_02195	COG0527	aspartate kinase activity
A361_02205	COG2814	Major facilitator Superfamily
A361_02210	COG0788	formyltetrahydrofolate deformylase activity
A361_02220	COG3540	Alkaline phosphatase
A361_02225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A361_02235	COG0861	Integral membrane protein TerC family
A361_02270	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A361_02275	COG3738	Protein conserved in bacteria
A361_02290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A361_02295	COG0586	Pfam SNARE associated Golgi protein
A361_02305	COG3546	catalase activity
A361_02310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A361_02315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A361_02320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A361_02325	COG1120	ATPase activity
A361_02340	COG2329	Antibiotic biosynthesis monooxygenase
A361_02345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A361_02350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A361_02355	COG1917	Cupin 2, conserved barrel domain protein
A361_02355	COG4977	sequence-specific DNA binding
A361_02370	COG4264	IucA IucC family
A361_02375	COG0318	PFAM AMP-dependent synthetase and ligase
A361_02380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A361_02390	COG1082	Xylose isomerase domain protein TIM barrel
A361_02400	COG1132	(ABC) transporter
A361_02415	COG1263	PTS System
A361_02415	COG2190	(PTS) system
A361_02415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A361_02430	COG0450	alkyl hydroperoxide reductase
A361_02435	COG1695	Transcriptional regulator
A361_02445	COG2824	Alkylphosphonate utilization operon protein PhnA
A361_02450	COG5002	protein histidine kinase activity
A361_02455	COG0656	L-ascorbic acid biosynthetic process
A361_02460	COG2814	Major facilitator Superfamily
A361_02465	COG1733	regulation of RNA biosynthetic process
A361_02595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A361_02600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A361_02620	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A361_02630	COG2211	Major facilitator Superfamily
A361_02645	COG0737	Belongs to the 5'-nucleotidase family
A361_02645	COG1525	nuclease
A361_02645	COG4085	toxin activity
A361_02655	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A361_02660	COG0352	thiamine-phosphate diphosphorylase activity
A361_02665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A361_02675	COG2022	thiamine diphosphate biosynthetic process
A361_02680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A361_02700	COG2205	protein histidine kinase activity
A361_02705	COG0745	RESPONSE REGULATOR receiver
A361_02720	COG3402	PFAM membrane-flanked domain
A361_02725	COG3428	Bacterial PH domain
A361_02740	COG0745	RESPONSE REGULATOR receiver
A361_02745	COG0642	Histidine kinase
A361_02770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A361_02775	COG1136	(ABC) transporter
A361_02780	COG0577	efflux transmembrane transporter activity
A361_02790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A361_02815	COG0778	Nitroreductase
A361_02820	COG1846	Transcriptional regulator
A361_02825	COG2226	methyltransferase
A361_02835	COG0626	cystathionine gamma-synthase activity
A361_02840	COG2154	pterin-4-alpha-carbinolamine dehydratase
A361_02845	COG3186	Phenylalanine-4-hydroxylase
A361_02850	COG4682	membrane
A361_02860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A361_02875	COG4912	Dna alkylation repair
A361_02930	COG1131	(ABC) transporter
A361_02940	COG0456	acetyltransferase
A361_02945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A361_02955	COG1393	Belongs to the ArsC family
A361_03000	COG3773	Cell wall hydrolase
A361_03025	COG4638	Rieske (2fe-2S)
A361_03030	COG1012	belongs to the aldehyde dehydrogenase family
A361_03035	COG0473	3-isopropylmalate dehydrogenase activity
A361_03040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A361_03045	COG0697	spore germination
A361_03050	COG1522	sequence-specific DNA binding
A361_03065	COG4572	Cation transport regulator
A361_03080	COG2801	Transposase and inactivated derivatives
A361_03095	COG0745	RESPONSE REGULATOR receiver
A361_03100	COG5002	protein histidine kinase activity
A361_03115	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
A361_03125	COG2076	Multidrug Resistance protein
A361_03130	COG2076	Multidrug Resistance protein
A361_03135	COG2312	Erythromycin esterase
A361_03145	COG0861	Integral membrane protein TerC family
A361_03150	COG4213	ABC transporter substrate-binding protein
A361_03155	COG1129	ABC transporter
A361_03160	COG1172	Belongs to the binding-protein-dependent transport system permease family
A361_03170	COG2972	Histidine kinase
A361_03175	COG2207	Transcriptional regulator
A361_03175	COG4753	response regulator
A361_03180	COG4213	ABC transporter substrate-binding protein
A361_03190	COG3340	Belongs to the peptidase S51 family
A361_03205	COG1846	Transcriptional regulator
A361_03205	COG0456	acetyltransferase
A361_03215	COG1940	carbohydrate kinase activity
A361_03225	COG0110	maltose O-acetyltransferase activity
A361_03240	COG2367	Beta-lactamase
A361_03250	COG3546	catalase activity
A361_03255	COG2502	aspartate--ammonia ligase
A361_03260	COG0584	glycerophosphoryl diester phosphodiesterase
A361_03265	COG1247	-acetyltransferase
A361_03280	COG1473	amidohydrolase
A361_03340	COG0640	Transcriptional regulator
A361_03345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A361_03350	COG5002	protein histidine kinase activity
A361_03355	COG0745	RESPONSE REGULATOR receiver
A361_03360	COG0666	response to abiotic stimulus
A361_03375	COG1683	Conserved Protein
A361_03380	COG2814	Major facilitator Superfamily
A361_03400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A361_03420	COG0456	acetyltransferase
A361_03420	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A361_03430	COG0494	nUDIX hydrolase
A361_03460	COG1595	DNA-templated transcription, initiation
A361_03480	COG2323	membrane
A361_03500	COG0412	Dienelactone hydrolase
A361_03510	COG1301	dicarboxylic acid transport
A361_03535	COG0725	ABC transporter, periplasmic molybdate-binding protein
A361_03545	COG1131	(ABC) transporter
A361_03565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A361_03570	COG0456	acetyltransferase
A361_03580	COG1937	Protein conserved in bacteria
A361_03585	COG1937	Protein conserved in bacteria
A361_03590	COG2608	mercury ion transmembrane transporter activity
A361_03595	COG2217	Heavy metal translocating P-type atpase
A361_03615	COG0789	Transcriptional regulator
A361_03620	COG1064	alcohol dehydrogenase
A361_03630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A361_03645	COG0640	Transcriptional regulator
A361_03650	COG0346	lactoylglutathione lyase activity
A361_03655	COG3584	3D domain protein
A361_03655	COG3583	domain protein
A361_03665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A361_03670	COG0477	Major facilitator Superfamily
A361_03675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A361_03680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A361_03685	COG2318	DinB family
A361_03690	COG2329	Antibiotic biosynthesis monooxygenase
A361_03705	COG0668	transmembrane transport
A361_03835	COG2072	flavoprotein involved in K transport
A361_03850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A361_03860	COG2329	Antibiotic biosynthesis monooxygenase
A361_03865	COG2851	Citrate transporter
A361_03870	COG4565	transcriptional regulatory protein
A361_03875	COG3290	protein histidine kinase activity
A361_03880	COG3973	AAA domain
A361_03885	COG2814	Major facilitator Superfamily
A361_03890	COG0167	dihydroorotate dehydrogenase activity
A361_03895	COG1846	Transcriptional regulator
A361_03900	COG0456	acetyltransferase
A361_03905	COG2808	Putative FMN-binding domain
A361_03945	COG2072	flavoprotein involved in K transport
A361_04010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A361_04015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A361_04075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A361_04095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A361_04115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A361_04125	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
A361_04155	COG2226	methyltransferase
A361_04165	COG2318	DinB family
A361_04175	COG1335	isochorismatase
A361_04180	COG1522	sequence-specific DNA binding
A361_04185	COG2207	Transcriptional regulator
A361_04200	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A361_04220	COG0702	epimerase
A361_04235	COG0745	RESPONSE REGULATOR receiver
A361_04235	COG3706	GGDEF domain
A361_04275	COG5002	protein histidine kinase activity
A361_04315	COG0305	Participates in initiation and elongation during chromosome replication
A361_04330	COG0697	spore germination
A361_04340	COG0726	polysaccharide deacetylase
A361_04345	COG2391	methyltransferase activity
A361_04350	COG2936	dipeptidyl-peptidase activity
A361_04360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A361_04370	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A361_04375	COG2169	Transcriptional regulator
A361_04380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A361_04405	COG0662	Cupin 2, conserved barrel domain protein
A361_04405	COG2207	Transcriptional regulator
A361_04410	COG0697	spore germination
A361_04425	COG2814	Major facilitator Superfamily
A361_04430	COG0778	Nitroreductase
A361_04430	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
A361_04445	COG0745	RESPONSE REGULATOR receiver
A361_04450	COG0642	Histidine kinase
A361_04460	COG1136	(ABC) transporter
A361_04475	COG0745	RESPONSE REGULATOR receiver
A361_04480	COG2205	protein histidine kinase activity
A361_04485	COG1136	(ABC) transporter
A361_04490	COG0577	efflux transmembrane transporter activity
A361_04495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A361_04500	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A361_04510	COG0463	Glycosyl transferase, family 2
A361_04525	COG1278	Cold shock
A361_04530	COG4978	Transcriptional regulator
A361_04530	COG0789	Transcriptional regulator
A361_04535	COG2814	Major facilitator Superfamily
A361_04550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A361_04555	COG1902	pentaerythritol trinitrate reductase activity
A361_04590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A361_04595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A361_04600	COG0577	efflux transmembrane transporter activity
A361_04605	COG1136	(ABC) transporter
A361_04610	COG1309	transcriptional regulator
A361_04615	COG3844	kynureninase activity
A361_04630	COG0733	neurotransmitter:sodium symporter activity
A361_04635	COG1366	Belongs to the anti-sigma-factor antagonist family
A361_04645	COG2155	Conserved Protein
A361_04650	COG0501	Belongs to the peptidase M48B family
A361_04670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A361_04685	COG0577	efflux transmembrane transporter activity
A361_04690	COG1136	(ABC) transporter
A361_04695	COG5505	Protein of unknown function (DUF819)
A361_04700	COG2233	PERMEase
A361_04715	COG0318	PFAM AMP-dependent synthetase and ligase
A361_04740	COG0789	Transcriptional regulator
A361_04755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A361_04780	COG3135	benzoate transporter
A361_04790	COG3835	regulator
A361_04820	COG1247	-acetyltransferase
A361_04835	COG1802	Transcriptional regulator
A361_04840	COG0277	FAD linked oxidase domain protein
A361_04845	COG0247	lactate metabolic process
A361_04850	COG0579	oxidoreductase
A361_04865	COG3279	Response regulator of the LytR AlgR family
A361_04870	COG0427	acetyl-CoA hydrolase
A361_04875	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A361_04880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A361_04885	COG3290	protein histidine kinase activity
A361_04890	COG4565	transcriptional regulatory protein
A361_04895	COG1301	dicarboxylic acid transport
A361_04900	COG2271	Major facilitator Superfamily
A361_04905	COG1366	Belongs to the anti-sigma-factor antagonist family
A361_04925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A361_04945	COG0588	phosphoglycerate mutase activity
A361_04950	COG2205	protein histidine kinase activity
A361_04965	COG0753	catalase activity
A361_04965	COG0693	protein deglycase activity
A361_04970	COG2207	Transcriptional regulator
A361_04970	COG3708	Transcriptional regulator
A361_04975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A361_04980	COG2318	DinB family
A361_04995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A361_05020	COG2176	DNA-directed DNA polymerase activity
A361_05025	COG5002	protein histidine kinase activity
A361_05030	COG4895	conserved protein (DUF2196)
A361_05045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A361_05050	COG1966	Carbon starvation protein
A361_05060	COG3275	phosphorelay sensor kinase activity
A361_05085	COG0024	Methionine aminopeptidase
A361_05090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A361_05095	COG0604	alcohol dehydrogenase
A361_05100	COG2706	6-phosphogluconolactonase activity
A361_05115	COG1366	Belongs to the anti-sigma-factor antagonist family
A361_05120	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
A361_05125	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A361_05140	COG0446	pyridine nucleotide-disulphide oxidoreductase
A361_05150	COG2814	Major facilitator Superfamily
A361_05155	COG1115	amino acid carrier protein
A361_05165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A361_05170	COG0805	protein transport
A361_05180	COG1063	alcohol dehydrogenase
A361_05185	COG5002	protein histidine kinase activity
A361_05190	COG0737	Belongs to the 5'-nucleotidase family
A361_05200	COG0513	Belongs to the DEAD box helicase family
A361_05205	COG0154	amidase activity
A361_05210	COG0723	plastoquinol--plastocyanin reductase activity
A361_05210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A361_05220	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A361_05225	COG0697	spore germination
A361_05235	COG0626	cystathionine gamma-synthase activity
A361_05260	COG2720	vancomycin resistance protein
A361_05265	COG1657	PFAM Prenyltransferase squalene oxidase
A361_05270	COG1994	Peptidase M50
A361_05280	COG1842	Phage shock protein A
A361_05300	COG2197	response regulator
A361_05330	COG2244	polysaccharide biosynthetic process
A361_05345	COG0598	Magnesium transport protein CorA
A361_05360	COG1607	acyl-coa hydrolase
A361_05370	COG0405	Gamma-glutamyltransferase
A361_05390	COG2801	Transposase and inactivated derivatives
A361_05395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A361_05400	COG0312	modulator of DNA gyrase
A361_05405	COG0312	modulator of DNA gyrase
A361_05410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A361_05425	COG0805	protein transport
A361_05430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A361_05455	COG0670	Belongs to the BI1 family
A361_05460	COG1970	mechanosensitive ion channel activity
A361_05465	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A361_05475	COG4145	pantothenate transmembrane transporter activity
A361_05485	COG2309	aminopeptidase activity
A361_05535	COG1366	Belongs to the anti-sigma-factor antagonist family
A361_05540	COG2986	histidine ammonia-lyase
A361_05550	COG0450	alkyl hydroperoxide reductase
A361_05575	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A361_05580	COG1360	Flagellar Motor Protein
A361_05585	COG2814	Major facilitator Superfamily
A361_05590	COG1846	Transcriptional regulator
A361_05595	COG1115	amino acid carrier protein
A361_05600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A361_05600	COG1522	sequence-specific DNA binding
A361_05605	COG2313	pseudouridylate synthase activity
A361_05610	COG3764	Sortase (surface protein transpeptidase)
A361_05625	COG0681	Belongs to the peptidase S26 family
A361_05650	COG1396	sequence-specific DNA binding
A361_05655	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
A361_05660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A361_05665	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A361_05670	COG2188	Transcriptional regulator
A361_05675	COG0693	protein deglycase activity
A361_05680	COG4840	Belongs to the UPF0435 family
A361_05690	COG1295	ribonuclease BN
A361_05695	COG2217	Heavy metal translocating P-type atpase
A361_05700	COG0477	Major facilitator Superfamily
A361_05710	COG1960	acyl-CoA dehydrogenase activity
A361_05720	COG0387	Pfam Sodium calcium exchanger
A361_05730	COG0535	radical SAM domain protein
A361_05750	COG2801	Transposase and inactivated derivatives
A361_05770	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A361_05775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A361_05780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A361_05790	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
A361_05820	COG0386	Belongs to the glutathione peroxidase family
A361_05845	COG3189	MarR family transcriptional regulator
A361_05850	COG0402	S-adenosylhomocysteine deaminase activity
A361_05855	COG0402	S-adenosylhomocysteine deaminase activity
A361_05860	COG0747	negative chemotaxis
A361_05865	COG0402	S-adenosylhomocysteine deaminase activity
A361_05870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A361_05875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A361_05880	COG3257	ureidoglycine aminohydrolase activity
A361_05900	COG3275	phosphorelay sensor kinase activity
A361_05905	COG4608	Belongs to the ABC transporter superfamily
A361_05910	COG0444	Belongs to the ABC transporter superfamily
A361_05915	COG0601	transmembrane transport
A361_05925	COG0747	negative chemotaxis
A361_05930	COG0402	S-adenosylhomocysteine deaminase activity
A361_05935	COG0402	S-adenosylhomocysteine deaminase activity
A361_05940	COG0666	response to abiotic stimulus
A361_05950	COG2267	carboxylic ester hydrolase activity
A361_05965	COG0069	glutamate synthase activity
A361_05970	COG0702	epimerase
A361_05975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A361_05985	COG2508	Transcriptional regulator
A361_05990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A361_05995	COG0506	proline dehydrogenase activity
A361_06000	COG0683	leucine binding
A361_06025	COG0584	glycerophosphoryl diester phosphodiesterase
A361_06030	COG1132	(ABC) transporter
A361_06035	COG1132	(ABC) transporter
A361_06040	COG2304	oxidoreductase activity
A361_06045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A361_06060	COG1090	epimerase
A361_06070	COG4221	oxidoreductase activity
A361_06090	COG1988	membrane-bound metal-dependent
A361_06095	COG1194	a g-specific adenine glycosylase
A361_06105	COG1028	Short-chain dehydrogenase reductase Sdr
A361_06125	COG1132	(ABC) transporter
A361_06130	COG0444	Belongs to the ABC transporter superfamily
A361_06135	COG4608	Belongs to the ABC transporter superfamily
A361_06140	COG0747	negative chemotaxis
A361_06155	COG4129	membrane
A361_06160	COG0070	glutamate synthase
A361_06160	COG0067	glutamate synthase
A361_06160	COG0069	glutamate synthase activity
A361_06170	COG4555	ABC transporter
A361_06190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A361_06200	COG2096	Adenosyltransferase
A361_06205	COG0735	belongs to the Fur family
A361_06340	COG2972	Histidine kinase
A361_06355	COG0673	inositol 2-dehydrogenase activity
A361_06360	COG0673	inositol 2-dehydrogenase activity
A361_06375	COG3382	B3 4 domain protein
A361_06380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A361_06390	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A361_06395	COG0778	Nitroreductase
A361_06400	COG2766	serine protein kinase
A361_06425	COG0460	homoserine dehydrogenase
A361_06445	COG2094	Belongs to the DNA glycosylase MPG family
A361_06450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A361_06455	COG1823	symporter activity
A361_06460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A361_06465	COG2252	PERMEase
A361_06470	COG4187	Peptidase family M20/M25/M40
A361_06475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A361_06480	COG0306	phosphate transporter
A361_06485	COG1392	Phosphate transport regulator
A361_06495	COG5566	PFAM Mor transcription activator
A361_06500	COG3973	AAA domain
A361_06505	COG0656	L-ascorbic acid biosynthetic process
A361_06510	COG2261	transglycosylase associated protein
A361_06515	COG0564	pseudouridine synthase activity
A361_06525	COG3118	belongs to the thioredoxin family
A361_06535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A361_06535	COG3153	acetyltransferase
A361_06540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A361_06545	COG4221	oxidoreductase activity
A361_06550	COG4585	Histidine kinase
A361_06550	COG2203	Gaf domain
A361_06555	COG2197	response regulator
A361_06575	COG0745	RESPONSE REGULATOR receiver
A361_06580	COG3850	Histidine kinase
A361_06580	COG5002	protein histidine kinase activity
A361_06595	COG2719	SpoVR family
A361_06605	COG2210	Belongs to the sulfur carrier protein TusA family
A361_06610	COG0425	Belongs to the sulfur carrier protein TusA family
A361_06610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_06615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_06615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A361_06620	COG0425	Belongs to the sulfur carrier protein TusA family
A361_06625	COG0730	response to heat
A361_06630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A361_06635	COG1295	ribonuclease BN
A361_06645	COG2252	PERMEase
A361_06655	COG0640	Transcriptional regulator
A361_06665	COG0745	RESPONSE REGULATOR receiver
A361_06670	COG5002	protein histidine kinase activity
A361_06670	COG3850	Histidine kinase
A361_06675	COG1253	flavin adenine dinucleotide binding
A361_06690	COG1253	flavin adenine dinucleotide binding
A361_06695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A361_06700	COG3852	Histidine kinase
A361_06715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A361_06730	COG2814	Major facilitator Superfamily
A361_06735	COG1595	DNA-templated transcription, initiation
A361_06755	COG0393	Putative heavy-metal-binding
A361_06765	COG1132	(ABC) transporter
A361_06770	COG1132	(ABC) transporter
A361_06790	COG3842	ATPase activity
A361_06795	COG2508	Transcriptional regulator
A361_06800	COG1937	Protein conserved in bacteria
A361_06815	COG0189	ligase activity
A361_06820	COG0189	ligase activity
A361_06825	COG0189	ligase activity
A361_06830	COG0189	ligase activity
A361_06835	COG4399	Belongs to the UPF0754 family
A361_06840	COG3679	Belongs to the UPF0342 family
A361_06845	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A361_06855	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A361_06860	COG1122	ATPase activity
A361_06865	COG4721	ABC-type cobalt transport system, permease component
A361_06875	COG0561	phosphatase activity
A361_06880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A361_06885	COG0318	PFAM AMP-dependent synthetase and ligase
A361_06890	COG1024	Enoyl-CoA hydratase
A361_06900	COG4152	abc transporter atp-binding protein
A361_06905	COG1668	transmembrane transport
A361_06910	COG1280	lysine exporter protein (LysE YggA)
A361_06915	COG0420	3'-5' exonuclease activity
A361_06920	COG4717	serine-type aminopeptidase activity
A361_06925	COG1380	Effector of murein hydrolase LrgA
A361_06930	COG1346	cytolysis
A361_06935	COG3481	metal-dependent phosphohydrolase, HD sub domain
A361_06945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A361_06965	COG1846	Transcriptional regulator
A361_06985	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A361_06990	COG0537	adenosine 5'-monophosphoramidase activity
A361_06995	COG1131	(ABC) transporter
A361_07000	COG4473	ABC transporter
A361_07010	COG1473	amidohydrolase
A361_07015	COG0671	phosphoesterase, PA-phosphatase related
A361_07020	COG3069	C4-dicarboxylate transmembrane transporter activity
A361_07030	COG4585	Histidine kinase
A361_07035	COG2197	response regulator
A361_07040	COG2329	Antibiotic biosynthesis monooxygenase
A361_07045	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A361_07060	COG1309	transcriptional regulator
A361_07065	COG1511	domain protein
A361_07070	COG1234	tRNA 3'-trailer cleavage
A361_07075	COG0095	Lipoate-protein ligase
A361_07080	COG0318	PFAM AMP-dependent synthetase and ligase
A361_07085	COG1024	Enoyl-CoA hydratase
A361_07105	COG1396	sequence-specific DNA binding
A361_07110	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A361_07120	COG0501	Belongs to the peptidase M48B family
A361_07125	COG3340	Belongs to the peptidase S51 family
A361_07135	COG4903	ComK protein
A361_07145	COG1506	peptidase
A361_07145	COG4946	Tricorn protease homolog
A361_07145	COG0823	Involved in the tonB-independent uptake of proteins
A361_07150	COG1316	TRANSCRIPTIONal
A361_07155	COG0398	Pfam SNARE associated Golgi protein
A361_07170	COG1028	Short-chain dehydrogenase reductase Sdr
A361_07175	COG0183	Belongs to the thiolase family
A361_07185	COG2814	Major facilitator Superfamily
A361_07190	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A361_07195	COG1074	ATP-dependent DNA helicase activity
A361_07200	COG1403	HNH endonuclease
A361_07235	COG0318	PFAM AMP-dependent synthetase and ligase
A361_07240	COG2311	Membrane
A361_07245	COG0179	Fumarylacetoacetate (FAA) hydrolase
A361_07255	COG3300	MHYT domain
A361_07255	COG5001	Diguanylate cyclase
A361_07265	COG0367	asparagine synthase
A361_07270	COG0534	Mate efflux family protein
A361_07280	COG2182	Extracellular solute-binding protein
A361_07285	COG1175	transmembrane transport
A361_07290	COG3833	ABC-type maltose transport systems, permease component
A361_07295	COG0366	Alpha amylase catalytic
A361_07295	COG1874	Beta-galactosidase
A361_07300	COG1609	Transcriptional regulator
A361_07305	COG1028	Short-chain dehydrogenase reductase Sdr
A361_07315	COG1666	GTP binding
A361_07320	COG2996	Protein conserved in bacteria
A361_07325	COG1307	EDD domain protein, DegV family
A361_07330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A361_07345	COG0561	phosphatase activity
A361_07350	COG1073	alpha beta
A361_07355	COG2151	metal-sulfur cluster biosynthetic enzyme
A361_07365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A361_07370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A361_07375	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
A361_07380	COG0303	'Molybdopterin
A361_07385	COG1763	Mo-molybdopterin cofactor biosynthetic process
A361_07395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A361_07400	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A361_07405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A361_07415	COG0505	Belongs to the CarA family
A361_07425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A361_07440	COG0542	response to heat
A361_07450	COG2267	carboxylic ester hydrolase activity
A361_07460	COG1744	ABC transporter substrate-binding protein PnrA-like
A361_07485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A361_07490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A361_07495	COG5504	Zn-dependent protease
A361_07500	COG0444	Belongs to the ABC transporter superfamily
A361_07505	COG4608	Belongs to the ABC transporter superfamily
A361_07515	COG0601	transmembrane transport
A361_07520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A361_07530	COG0180	Tryptophanyl-tRNA synthetase
A361_07535	COG4166	transmembrane transport
A361_07540	COG0601	transmembrane transport
A361_07545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A361_07550	COG0444	Belongs to the ABC transporter superfamily
A361_07555	COG4608	Belongs to the ABC transporter superfamily
A361_07570	COG0456	acetyltransferase
A361_07575	COG1393	Belongs to the ArsC family
A361_07590	COG1164	Oligoendopeptidase f
A361_07600	COG2346	COG2346, Truncated hemoglobins
A361_07605	COG0741	lytic transglycosylase activity
A361_07610	COG4116	CYTH
A361_07620	COG2357	RelA SpoT domain protein
A361_07625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A361_07630	COG0564	pseudouridine synthase activity
A361_07635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A361_07640	COG2239	Acts as a magnesium transporter
A361_07645	COG0475	glutathione-regulated potassium exporter activity
A361_07645	COG0569	domain protein
A361_07650	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A361_07680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A361_07695	COG0210	DNA helicase
A361_07705	COG2323	membrane
A361_07710	COG2153	protein acetylation
A361_07715	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A361_07720	COG2382	esterase
A361_07755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A361_07775	COG0556	nucleotide-excision repair
A361_07785	COG1396	sequence-specific DNA binding
A361_07815	COG5377	YqaJ viral recombinase family
A361_07820	COG3723	Recombinational DNA repair protein, rece pathway
A361_07825	COG1522	sequence-specific DNA binding
A361_07840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A361_07850	COG2323	membrane
A361_07875	COG3728	DNA packaging
A361_07875	COG5484	DNA packaging
A361_07890	COG2369	cell adhesion
A361_08010	COG0506	proline dehydrogenase activity
A361_08020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A361_08020	COG2190	(PTS) system
A361_08020	COG1263	PTS System
A361_08040	COG4948	Mandelate Racemase Muconate Lactonizing
A361_08045	COG1612	heme a metabolic process
A361_08055	COG0004	ammonium transporteR
A361_08065	COG2176	DNA-directed DNA polymerase activity
A361_08085	COG3871	stress protein (general stress protein 26)
A361_08100	COG1966	Carbon starvation protein
A361_08110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A361_08115	COG0584	glycerophosphoryl diester phosphodiesterase
A361_08125	COG1585	Membrane protein implicated in regulation of membrane protease activity
A361_08130	COG2268	Band 7 protein
A361_08150	COG4412	M6 family metalloprotease domain protein
A361_08150	COG1404	Belongs to the peptidase S8 family
A361_08170	COG1175	transmembrane transport
A361_08175	COG0395	ABC-type sugar transport system, permease component
A361_08185	COG0084	hydrolase, TatD family'
A361_08190	COG1116	anion transmembrane transporter activity
A361_08195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A361_08205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A361_08210	COG3339	Conserved Protein
A361_08215	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A361_08220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A361_08225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A361_08225	COG1263	PTS System
A361_08230	COG0366	Alpha amylase catalytic
A361_08235	COG0366	Alpha amylase catalytic
A361_08240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A361_08245	COG1988	membrane-bound metal-dependent
A361_08250	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A361_08260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A361_08275	COG1191	sigma factor activity
A361_08290	COG0247	lactate metabolic process
A361_08295	COG0277	FAD linked oxidase domain protein
A361_08300	COG3835	regulator
A361_08305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A361_08320	COG0247	lactate metabolic process
A361_08325	COG1139	Iron-sulfur cluster binding protein
A361_08330	COG1556	Lactate utilization protein
A361_08370	COG2964	Protein conserved in bacteria
A361_08390	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A361_08410	COG3594	Acyltransferase
A361_08415	COG0840	transmembrane signaling receptor activity
A361_08420	COG5002	protein histidine kinase activity
A361_08425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A361_08430	COG0640	Transcriptional regulator
A361_08435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A361_08440	COG0436	Aminotransferase
A361_08445	COG1850	ribulose-bisphosphate carboxylase activity
A361_08450	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
A361_08455	COG0235	Class ii aldolase
A361_08460	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
A361_08475	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A361_08480	COG0644	oxidoreductase
A361_08495	COG2223	nitrite transmembrane transporter activity
A361_08500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A361_08505	COG3852	Histidine kinase
A361_08510	COG0737	Belongs to the 5'-nucleotidase family
A361_08515	COG1846	Transcriptional regulator
A361_08525	COG0542	response to heat
A361_08530	COG3949	Membrane
A361_08545	COG4873	Protein conserved in bacteria
A361_08555	COG1028	Short-chain dehydrogenase reductase Sdr
A361_08560	COG0714	Associated with various cellular activities
A361_08580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A361_08585	COG0390	transport system, permease component
A361_08600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A361_08610	COG2084	Dehydrogenase
A361_08620	COG0436	Aminotransferase
A361_08630	COG1714	RDD family
A361_08640	COG2270	Major facilitator Superfamily
A361_08645	COG0835	chemotaxis
A361_08645	COG0784	Response regulator, receiver
A361_08670	COG1376	ErfK ybiS ycfS ynhG family protein
A361_08675	COG1408	metallophosphoesterase
A361_08680	COG1028	Short-chain dehydrogenase reductase Sdr
A361_08690	COG2200	EAL domain
A361_08715	COG4703	Protein of unknown function (DUF1797)
A361_08720	COG0517	IMP dehydrogenase activity
A361_08725	COG0477	Major facilitator Superfamily
A361_08730	COG0583	DNA-binding transcription factor activity
A361_08735	COG2171	N-acyltransferase activity
A361_08740	COG1473	amidohydrolase
A361_08745	COG0668	transmembrane transport
A361_08750	COG1132	(ABC) transporter
A361_08755	COG1132	(ABC) transporter
A361_08760	COG0569	domain protein
A361_08765	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A361_08775	COG0561	phosphatase activity
A361_08785	COG0497	DNA recombination
A361_08795	COG0022	dehydrogenase e1 component
A361_08800	COG0508	dehydrogenase complex catalyzes the overall conversion of
A361_08820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A361_08845	COG1982	Orn Lys Arg decarboxylase major
A361_08855	COG4476	Belongs to the UPF0223 family
A361_08860	COG4493	Belongs to the UPF0637 family
A361_08870	COG0483	inositol monophosphate 1-phosphatase activity
A361_08900	COG4896	Protein conserved in bacteria
A361_08915	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A361_08920	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A361_08925	COG2066	Belongs to the glutaminase family
A361_08930	COG4838	Belongs to the UPF0358 family
A361_08935	COG0772	Belongs to the SEDS family
A361_08940	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A361_08945	COG1612	heme a metabolic process
A361_08975	COG3336	cytochrome c oxidase
A361_09010	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A361_09015	COG2340	Cysteine-rich secretory protein family
A361_09045	COG3679	Belongs to the UPF0342 family
A361_09050	COG4471	UPF0298 protein
A361_09070	COG0742	ribosomal rna small subunit methyltransferase
A361_09075	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A361_09080	COG3314	Sporulation integral membrane protein YlbJ
A361_09085	COG1752	Esterase of the alpha-beta hydrolase superfamily
A361_09090	COG3480	Lon protease (S16) C-terminal proteolytic domain
A361_09095	COG1323	Belongs to the UPF0348 family
A361_09100	COG1399	metal-binding, possibly nucleic acid-binding protein
A361_09105	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A361_09110	COG1024	Enoyl-CoA hydratase
A361_09120	COG0454	-acetyltransferase
A361_09125	COG0439	Biotin carboxylase
A361_09130	COG0511	ligase activity, forming carbon-carbon bonds
A361_09135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A361_09140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A361_09150	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
A361_09155	COG2001	Belongs to the MraZ family
A361_09160	COG0275	rRNA processing
A361_09175	COG0768	penicillin binding
A361_09180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A361_09190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A361_09195	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A361_09200	COG0772	Belongs to the SEDS family
A361_09205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A361_09210	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A361_09215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A361_09220	COG3879	Bacterial protein of unknown function (DUF881)
A361_09225	COG3879	Bacterial protein of unknown function (DUF881)
A361_09230	COG3856	small basic protein
A361_09235	COG0849	cell division
A361_09240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A361_09255	COG1191	sigma factor activity
A361_09260	COG1191	sigma factor activity
A361_09265	COG1873	PFAM PRC-barrel domain
A361_09275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A361_09280	COG1799	cell septum assembly
A361_09285	COG0762	integral membrane protein
A361_09290	COG2302	S4 RNA-binding domain
A361_09300	COG3599	regulation of cell shape
A361_09305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A361_09320	COG0564	pseudouridine synthase activity
A361_09325	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A361_09335	COG0540	Belongs to the ATCase OTCase family
A361_09340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A361_09345	COG0505	Belongs to the CarA family
A361_09350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A361_09355	COG0543	2 iron, 2 sulfur cluster binding
A361_09360	COG0167	dihydroorotate dehydrogenase activity
A361_09365	COG0284	orotidine-5'-phosphate decarboxylase activity
A361_09380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A361_09385	COG1561	YicC-like family, N-terminal region
A361_09390	COG2052	Domain of unknown function (DUF370)
A361_09395	COG0194	GDP metabolic process
A361_09400	COG1758	RNA polymerase activity
A361_09405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A361_09410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A361_09420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A361_09425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A361_09425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A361_09435	COG0631	protein serine/threonine phosphatase activity
A361_09440	COG2815	serine threonine protein kinase
A361_09440	COG0515	serine threonine protein kinase
A361_09445	COG1162	GTPase activity
A361_09450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A361_09455	COG1564	THIamine pyrophosphokinase
A361_09465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A361_09470	COG1302	Protein conserved in bacteria
A361_09475	COG1461	Dihydroxyacetone kinase
A361_09480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A361_09485	COG1349	DNA-binding transcription factor activity
A361_09490	COG0416	fatty acid biosynthetic process
A361_09495	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A361_09500	COG1028	Short-chain dehydrogenase reductase Sdr
A361_09505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A361_09510	COG0571	ribonuclease III activity
A361_09515	COG1196	nuclear chromosome segregation
A361_09520	COG0552	protein localization to endoplasmic reticulum
A361_09530	COG1131	(ABC) transporter
A361_09545	COG0714	Associated with various cellular activities
A361_09565	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
A361_09570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A361_09580	COG1837	Belongs to the UPF0109 family
A361_09590	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A361_09595	COG0336	Belongs to the RNA methyltransferase TrmD family
A361_09635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A361_09640	COG0758	DNA mediated transformation
A361_09645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A361_09650	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
A361_09655	COG4974	Belongs to the 'phage' integrase family
A361_09660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A361_09665	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A361_09670	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A361_09675	COG1815	bacterial-type flagellum-dependent cell motility
A361_09680	COG1558	bacterial-type flagellum-dependent cell motility
A361_09685	COG1677	Flagellar hook-basal body complex protein FliE
A361_09690	COG1766	The M ring may be actively involved in energy transduction
A361_09695	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A361_09700	COG1317	bacterial-type flagellum organization
A361_09705	COG1157	protein secretion by the type III secretion system
A361_09710	COG2882	bacterial-type flagellum organization
A361_09725	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A361_09735	COG4786	Flagellar basal body rod
A361_09740	COG1582	Flagellar protein (FlbD)
A361_09745	COG1580	Controls the rotational direction of flagella during chemotaxis
A361_09750	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A361_09755	COG1776	CheC inhibitor of MCP methylation
A361_09755	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A361_09760	COG2201	protein-glutamate methylesterase activity
A361_09765	COG3190	flagellar
A361_09770	COG1338	Plays a role in the flagellum-specific transport system
A361_09775	COG1987	bacterial-type flagellum assembly
A361_09780	COG1684	flagellar biosynthetic protein fliR
A361_09785	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A361_09790	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A361_09795	COG1419	protein localization to endoplasmic reticulum
A361_09800	COG0455	bacterial-type flagellum organization
A361_09805	COG2201	protein-glutamate methylesterase activity
A361_09810	COG0643	Histidine kinase
A361_09810	COG2198	Histidine kinase
A361_09815	COG0835	chemotaxis
A361_09820	COG1776	CheC inhibitor of MCP methylation
A361_09825	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
A361_09830	COG1191	sigma factor activity
A361_09860	COG0528	UMP kinase activity
A361_09865	COG0233	cytoplasmic translational termination
A361_09875	COG4589	Belongs to the CDS family
A361_09880	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A361_09885	COG0750	zinc metalloprotease
A361_09890	COG0442	prolyl-tRNA aminoacylation
A361_09895	COG2176	DNA-directed DNA polymerase activity
A361_09900	COG0779	Required for maturation of 30S ribosomal subunits
A361_09905	COG0195	Participates in both transcription termination and antitermination
A361_09910	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A361_09915	COG1358	cellular component organization or biogenesis
A361_09925	COG1550	Protein conserved in bacteria
A361_09935	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A361_09940	COG0196	riboflavin kinase activity
A361_09945	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A361_09950	COG1185	polyribonucleotide nucleotidyltransferase activity
A361_09955	COG0726	polysaccharide deacetylase
A361_09960	COG0612	Peptidase, M16
A361_09965	COG1873	PFAM PRC-barrel domain
A361_09970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A361_09975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A361_09985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A361_09990	COG0527	aspartate kinase activity
A361_10000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A361_10005	COG0740	serine-type endopeptidase activity
A361_10015	COG1674	ftsk spoiiie
A361_10015	COG4980	gas vesicle protein
A361_10020	COG2188	Transcriptional regulator
A361_10045	COG0612	Peptidase, M16
A361_10050	COG0612	Peptidase, M16
A361_10055	COG0300	oxidoreductase activity
A361_10070	COG1426	Protein conserved in bacteria
A361_10075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A361_10080	COG1058	Belongs to the CinA family
A361_10080	COG1546	Belongs to the CinA family
A361_10085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A361_10090	COG1418	mRNA catabolic process
A361_10095	COG1692	metallophosphoesterase
A361_10100	COG2359	stage V sporulation protein S
A361_10110	COG0674	pyruvate-flavodoxin oxidoreductase activity
A361_10110	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A361_10115	COG1013	pyruvate-flavodoxin oxidoreductase activity
A361_10120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A361_10125	COG4550	Control of competence regulator ComK, YlbF/YmcA
A361_10150	COG0346	lactoylglutathione lyase activity
A361_10220	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A361_10225	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A361_10230	COG1077	Cell shape determining protein MreB Mrl
A361_10235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A361_10240	COG1923	regulation of RNA biosynthetic process
A361_10245	COG0464	growth
A361_10250	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A361_10255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A361_10270	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A361_10275	COG2186	Transcriptional regulator
A361_10285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A361_10290	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A361_10295	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A361_10300	COG2860	membrane
A361_10305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A361_10310	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A361_10315	COG0789	Transcriptional regulator
A361_10320	COG0174	glutamine synthetase
A361_10350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A361_10360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A361_10365	COG4224	UPF0291 protein
A361_10380	COG3763	UPF0154 protein
A361_10445	COG0270	DNA (cytosine-5-)-methyltransferase activity
A361_10620	COG1674	ftsk spoiiie
A361_10640	COG1132	(ABC) transporter
A361_10645	COG1132	(ABC) transporter
A361_10650	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A361_10655	COG1522	sequence-specific DNA binding
A361_10665	COG0785	Cytochrome C biogenesis protein
A361_10670	COG2201	protein-glutamate methylesterase activity
A361_10675	COG4846	Membrane protein involved in cytochrome C biogenesis
A361_10690	COG4974	Belongs to the 'phage' integrase family
A361_10735	COG1674	ftsk spoiiie
A361_10895	COG1652	LysM domain
A361_10910	COG3628	GPW Gp25 family protein
A361_10915	COG3299	homolog of phage Mu protein gp47
A361_10965	COG1793	dna ligase
A361_10980	COG4807	Protein conserved in bacteria
A361_11000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A361_11015	COG2186	Transcriptional regulator
A361_11020	COG0277	FAD linked oxidase domain protein
A361_11025	COG0385	Bile acid
A361_11030	COG2271	Major facilitator Superfamily
A361_11035	COG1051	belongs to the nudix hydrolase family
A361_11035	COG1056	cytidyltransferase-related domain
A361_11040	COG3201	nicotinamide mononucleotide transporter
A361_11055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A361_11060	COG3773	Cell wall hydrolase
A361_11120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A361_11130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A361_11185	COG1309	transcriptional regulator
A361_11190	COG3173	Aminoglycoside phosphotransferase
A361_11195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_11195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A361_11215	COG1175	transmembrane transport
A361_11220	COG0395	ABC-type sugar transport system, permease component
A361_11235	COG2222	sugar isomerase
A361_11240	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A361_11245	COG3715	PTS system
A361_11250	COG3716	PTS system mannose fructose sorbose family IID component
A361_11260	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A361_11290	COG1929	Belongs to the glycerate kinase type-1 family
A361_11300	COG1959	2 iron, 2 sulfur cluster binding
A361_11305	COG0492	ferredoxin-NADP+ reductase activity
A361_11320	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
A361_11330	COG1028	Short-chain dehydrogenase reductase Sdr
A361_11340	COG1957	nucleoside hydrolase
A361_11345	COG0753	catalase activity
A361_11350	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A361_11355	COG0583	DNA-binding transcription factor activity
A361_11360	COG0281	malic enzyme
A361_11370	COG0517	IMP dehydrogenase activity
A361_11370	COG1125	glycine betaine transport
A361_11375	COG1174	glycine betaine transport
A361_11385	COG3681	Belongs to the UPF0597 family
A361_11390	COG2197	response regulator
A361_11400	COG0697	spore germination
A361_11425	COG3069	C4-dicarboxylate transmembrane transporter activity
A361_11470	COG2059	Chromate
A361_11475	COG2059	Chromate
A361_11500	COG2972	Histidine kinase
A361_11505	COG2207	Transcriptional regulator
A361_11505	COG4753	response regulator
A361_11510	COG1653	transport
A361_11515	COG1175	transmembrane transport
A361_11520	COG0395	ABC-type sugar transport system, permease component
A361_11525	COG5578	integral membrane protein
A361_11530	COG3507	Belongs to the glycosyl hydrolase 43 family
A361_11540	COG3622	Belongs to the hyi family
A361_11545	COG2084	Dehydrogenase
A361_11550	COG0741	lytic transglycosylase activity
A361_11565	COG1368	sulfuric ester hydrolase activity
A361_11570	COG1587	Uroporphyrinogen-III synthase
A361_11575	COG1609	Transcriptional regulator
A361_11600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A361_11610	COG2318	DinB family
A361_11620	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
A361_11625	COG0069	glutamate synthase activity
A361_11640	COG2814	Major facilitator Superfamily
A361_11660	COG1024	Enoyl-CoA hydratase
A361_11665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A361_11670	COG2720	vancomycin resistance protein
A361_11675	COG0840	transmembrane signaling receptor activity
A361_11685	COG0701	Predicted permease
A361_11690	COG0523	cobalamin synthesis protein
A361_11695	COG1028	Short-chain dehydrogenase reductase Sdr
A361_11710	COG1278	Cold shock
A361_11715	COG2323	membrane
A361_11730	COG0419	ATPase involved in DNA repair
A361_11735	COG0137	argininosuccinate synthase activity
A361_11745	COG5522	Integral membrane protein (intg_mem_TP0381)
A361_11750	COG5146	pantothenate kinase activity
A361_11760	COG0791	NLP P60 protein
A361_11760	COG1388	LysM domain
A361_11795	COG1086	Polysaccharide biosynthesis protein
A361_11810	COG0438	transferase activity, transferring glycosyl groups
A361_11845	COG1216	Glycosyl transferase, family 2
A361_11855	COG0730	response to heat
A361_11860	COG0529	Catalyzes the synthesis of activated sulfate
A361_11865	COG2046	Belongs to the sulfate adenylyltransferase family
A361_11870	COG0463	Glycosyl transferase, family 2
A361_11890	COG1876	peptidase activity
A361_11895	COG1363	Peptidase, m42
A361_11900	COG0628	permease
A361_11905	COG3264	Mechanosensitive ion channel
A361_11905	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
A361_11920	COG1199	ATP-dependent helicase activity
A361_11920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A361_11925	COG2364	Membrane
A361_11930	COG1368	sulfuric ester hydrolase activity
A361_11940	COG1388	LysM domain
A361_11955	COG5002	protein histidine kinase activity
A361_11970	COG1760	l-serine dehydratase
A361_11975	COG1760	l-serine dehydratase
A361_11980	COG1525	nuclease
A361_11985	COG2124	cytochrome p450
A361_12000	COG0217	transcriptional regulatory protein
A361_12010	COG3764	Sortase (surface protein transpeptidase)
A361_12025	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A361_12030	COG3396	Phenylacetate-CoA oxygenase
A361_12055	COG1024	Enoyl-CoA hydratase
A361_12060	COG1024	Enoyl-CoA hydratase
A361_12065	COG1250	3-hydroxyacyl-CoA dehydrogenase
A361_12070	COG0183	Belongs to the thiolase family
A361_12075	COG3327	negative regulation of DNA-templated transcription, initiation
A361_12100	COG4120	Belongs to the binding-protein-dependent transport system permease family
A361_12125	COG0022	dehydrogenase e1 component
A361_12140	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A361_12145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A361_12150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A361_12155	COG0179	Fumarylacetoacetate (FAA) hydrolase
A361_12165	COG1307	EDD domain protein, DegV family
A361_12170	COG0488	(ABC) transporter
A361_12180	COG0753	catalase activity
A361_12200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A361_12235	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A361_12245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A361_12265	COG0464	growth
A361_12270	COG0824	Thioesterase
A361_12280	COG4841	protein insertion into membrane
A361_12295	COG2843	Capsule synthesis protein
A361_12300	COG5002	protein histidine kinase activity
A361_12305	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A361_12325	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A361_12330	COG2252	PERMEase
A361_12340	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A361_12340	COG3608	succinylglutamate desuccinylase aspartoacylase
A361_12345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A361_12355	COG0746	molybdenum cofactor guanylyltransferase activity
A361_12370	COG2233	PERMEase
A361_12380	COG1335	isochorismatase
A361_12385	COG0163	prenyltransferase activity
A361_12395	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
A361_12410	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
A361_12420	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
A361_12425	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A361_12430	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A361_12435	COG3665	Urea carboxylase-associated protein
A361_12440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A361_12445	COG0402	S-adenosylhomocysteine deaminase activity
A361_12460	COG0187	DNA topoisomerase II activity
A361_12465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A361_12470	COG1115	amino acid carrier protein
A361_12505	COG1408	metallophosphoesterase
A361_12510	COG0726	polysaccharide deacetylase
A361_12525	COG2323	membrane
A361_12530	COG1113	amino acid transport
A361_12550	COG0326	Molecular chaperone. Has ATPase activity
A361_12565	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
A361_12590	COG1164	Oligoendopeptidase f
A361_12620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A361_12630	COG2197	response regulator
A361_12635	COG4585	Histidine kinase
A361_12640	COG3239	Fatty acid desaturase
A361_12650	COG5577	PFAM Coat F domain
A361_12680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A361_12685	COG1063	alcohol dehydrogenase
A361_12690	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A361_12700	COG2353	YceI-like domain
A361_12705	COG2027	D-alanyl-D-alanine carboxypeptidase
A361_12715	COG3695	enzyme binding
A361_12725	COG1404	Belongs to the peptidase S8 family
A361_12730	COG3663	DNA glycosylase
A361_12735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A361_12745	COG1418	mRNA catabolic process
A361_12755	COG2801	Transposase and inactivated derivatives
A361_12765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A361_12770	COG0346	lactoylglutathione lyase activity
A361_12795	COG2310	stress, protein
A361_12800	COG2310	stress, protein
A361_12810	COG4989	oxidoreductase activity
A361_12825	COG3584	3D domain protein
A361_12825	COG1388	LysM domain
A361_12830	COG5002	protein histidine kinase activity
A361_12840	COG1164	Oligoendopeptidase f
A361_12865	COG3361	conserved protein (COG2071)
A361_12880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A361_12885	COG1012	belongs to the aldehyde dehydrogenase family
A361_12890	COG1999	signal sequence binding
A361_12910	COG2030	dehydratase
A361_12915	COG0488	(ABC) transporter
A361_12925	COG1686	Belongs to the peptidase S11 family
A361_12935	COG2404	hydrolase activity, acting on ester bonds
A361_12945	COG0010	Belongs to the arginase family
A361_12950	COG1228	amidohydrolase
A361_12955	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
A361_12970	COG2340	Cysteine-rich secretory protein family
A361_12975	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A361_12990	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A361_13000	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A361_13000	COG0392	lysyltransferase activity
A361_13005	COG0706	membrane insertase activity
A361_13030	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
A361_13030	COG2105	PFAM AIG2 family protein
A361_13035	COG0318	PFAM AMP-dependent synthetase and ligase
A361_13040	COG0432	Pfam Uncharacterised protein family UPF0047
A361_13055	COG0508	dehydrogenase complex catalyzes the overall conversion of
A361_13060	COG0567	Dehydrogenase, E1 component
A361_13075	COG0626	cystathionine gamma-synthase activity
A361_13080	COG0626	cystathionine gamma-synthase activity
A361_13085	COG0646	methionine synthase
A361_13085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A361_13090	COG0646	methionine synthase
A361_13090	COG1410	methionine synthase
A361_13095	COG0546	phosphoglycolate phosphatase activity
A361_13125	COG0656	L-ascorbic acid biosynthetic process
A361_13130	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
A361_13135	COG2346	COG2346, Truncated hemoglobins
A361_13160	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
A361_13170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A361_13175	COG1845	cytochrome c oxidase, subunit III
A361_13180	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A361_13200	COG0534	Mate efflux family protein
A361_13205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A361_13210	COG5002	protein histidine kinase activity
A361_13220	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A361_13230	COG1176	ABC-type spermidine putrescine transport system, permease component I
A361_13245	COG0720	synthase
A361_13260	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A361_13265	COG1984	allophanate hydrolase subunit 2
A361_13270	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A361_13275	COG1914	H( )-stimulated, divalent metal cation uptake system
A361_13280	COG4336	lyase activity
A361_13285	COG0737	Belongs to the 5'-nucleotidase family
A361_13295	COG1028	Short-chain dehydrogenase reductase Sdr
A361_13305	COG0628	permease
A361_13320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A361_13325	COG2076	Multidrug Resistance protein
A361_13330	COG2076	Multidrug Resistance protein
A361_13340	COG0708	Exodeoxyribonuclease III
A361_13350	COG0352	thiamine-phosphate diphosphorylase activity
A361_13355	COG0351	phosphomethylpyrimidine kinase
A361_13360	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A361_13370	COG1764	response to oxidative stress
A361_13375	COG0561	phosphatase activity
A361_13380	COG1595	DNA-templated transcription, initiation
A361_13400	COG4990	cell redox homeostasis
A361_13410	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A361_13420	COG3773	Cell wall hydrolase
A361_13430	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A361_13435	COG4536	flavin adenine dinucleotide binding
A361_13470	COG1968	undecaprenyl-diphosphatase activity
A361_13485	COG1272	protein, Hemolysin III
A361_13545	COG1012	belongs to the aldehyde dehydrogenase family
A361_13550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A361_13560	COG4145	pantothenate transmembrane transporter activity
A361_13570	COG0066	3-isopropylmalate dehydratase activity
A361_13575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A361_13580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A361_13585	COG1802	Transcriptional regulator
A361_13590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A361_13605	COG0840	transmembrane signaling receptor activity
A361_13610	COG2814	Major facilitator Superfamily
A361_13625	COG1929	Belongs to the glycerate kinase type-1 family
A361_13630	COG2610	gluconate transmembrane transporter activity
A361_13635	COG3835	regulator
A361_13655	COG0529	Catalyzes the synthesis of activated sulfate
A361_13660	COG2046	Belongs to the sulfate adenylyltransferase family
A361_13665	COG0306	phosphate transporter
A361_13670	COG0175	sulfate reduction
A361_13675	COG2801	Transposase and inactivated derivatives
A361_13690	COG0673	inositol 2-dehydrogenase activity
A361_13695	COG1119	ATPase activity
A361_13715	COG1024	Enoyl-CoA hydratase
A361_13725	COG1802	Transcriptional regulator
A361_13735	COG0247	lactate metabolic process
A361_13740	COG0277	FAD linked oxidase domain protein
A361_13745	COG3829	transcription factor binding
A361_13745	COG3290	protein histidine kinase activity
A361_13755	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A361_13765	COG0039	L-malate dehydrogenase activity
A361_13770	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
A361_13775	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
A361_13790	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
A361_13795	COG1012	belongs to the aldehyde dehydrogenase family
A361_13795	COG1454	alcohol dehydrogenase
A361_13800	COG4816	utilization protein
A361_13805	COG4302	ethanolamine ammonia-lyase activity
A361_13810	COG4303	Ethanolamine ammonia lyase large subunit
A361_13820	COG4917	ethanolamine utilization protein
A361_13825	COG4810	utilization protein
A361_13830	COG3192	ethanolamine utilization protein
A361_13850	COG4303	Ethanolamine ammonia lyase large subunit
A361_13860	COG2814	Major facilitator Superfamily
A361_13865	COG1028	Short-chain dehydrogenase reductase Sdr
A361_13870	COG2226	methyltransferase
A361_13880	COG1960	acyl-CoA dehydrogenase activity
A361_13900	COG1250	3-hydroxyacyl-CoA dehydrogenase
A361_13905	COG1309	transcriptional regulator
A361_13910	COG0318	PFAM AMP-dependent synthetase and ligase
A361_13915	COG1028	Short-chain dehydrogenase reductase Sdr
A361_13935	COG2207	Transcriptional regulator
A361_13935	COG3708	Transcriptional regulator
A361_13950	COG0346	lactoylglutathione lyase activity
A361_13970	COG1309	transcriptional regulator
A361_13980	COG2357	RelA SpoT domain protein
A361_13985	COG1846	Transcriptional regulator
A361_13990	COG2814	Major facilitator Superfamily
A361_14015	COG0681	Belongs to the peptidase S26 family
A361_14025	COG3227	Zinc metalloprotease (Elastase)
A361_14040	COG0745	RESPONSE REGULATOR receiver
A361_14045	COG0642	Histidine kinase
A361_14050	COG1136	(ABC) transporter
A361_14055	COG0577	efflux transmembrane transporter activity
A361_14065	COG4821	SIS domain
A361_14070	COG0363	glucosamine-6-phosphate deaminase activity
A361_14075	COG1263	PTS System
A361_14075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A361_14080	COG3394	polysaccharide catabolic process
A361_14090	COG1486	melibiose metabolic process
A361_14095	COG1447	Phosphotransferase system cellobiose-specific component IIA
A361_14100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A361_14105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A361_14110	COG2188	Transcriptional regulator
A361_14115	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A361_14115	COG0456	acetyltransferase
A361_14120	COG0500	methyltransferase
A361_14150	COG1388	LysM domain
A361_14150	COG1705	Flagellar rod assembly protein muramidase FlgJ
A361_14155	COG3383	formate dehydrogenase (NAD+) activity
A361_14165	COG0584	glycerophosphoryl diester phosphodiesterase
A361_14180	COG5002	protein histidine kinase activity
A361_14185	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A361_14215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A361_14220	COG1098	S1 RNA binding domain
A361_14225	COG0385	Bile acid
A361_14230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A361_14250	COG0346	lactoylglutathione lyase activity
A361_14265	COG4638	Rieske (2fe-2S)
A361_14280	COG0028	Belongs to the TPP enzyme family
A361_14285	COG1028	Short-chain dehydrogenase reductase Sdr
A361_14305	COG1414	Transcriptional regulator
A361_14310	COG2267	carboxylic ester hydrolase activity
A361_14315	COG1268	BioY protein
A361_14320	COG0318	PFAM AMP-dependent synthetase and ligase
A361_14325	COG0183	Belongs to the thiolase family
A361_14380	COG0531	amino acid
A361_14385	COG0697	spore germination
A361_14390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A361_14395	COG0697	spore germination
A361_14400	COG1917	Cupin 2, conserved barrel domain protein
A361_14400	COG2207	Transcriptional regulator
A361_14425	COG1368	sulfuric ester hydrolase activity
A361_14430	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A361_14435	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A361_14440	COG1121	(ABC) transporter
A361_14445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A361_14450	COG0803	Belongs to the bacterial solute-binding protein 9 family
A361_14460	COG2814	Major facilitator Superfamily
A361_14460	COG0477	Major facilitator Superfamily
A361_14470	COG1070	Carbohydrate kinase
A361_14480	COG1940	carbohydrate kinase activity
A361_14490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A361_14495	COG0733	neurotransmitter:sodium symporter activity
A361_14505	COG0833	amino acid
A361_14510	COG4638	Rieske (2fe-2S)
A361_14515	COG1126	abc transporter atp-binding protein
A361_14535	COG1802	Transcriptional regulator
A361_14540	COG3835	regulator
A361_14550	COG3835	regulator
A361_14555	COG0473	3-isopropylmalate dehydrogenase activity
A361_14560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A361_14565	COG0183	Belongs to the thiolase family
A361_14570	COG1960	acyl-CoA dehydrogenase activity
A361_14575	COG1024	Enoyl-CoA hydratase
A361_14585	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A361_14590	COG1250	3-hydroxyacyl-CoA dehydrogenase
A361_14600	COG0436	Aminotransferase
A361_14615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A361_14630	COG0716	FMN binding
A361_14640	COG0716	FMN binding
A361_14680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A361_14715	COG1176	ABC-type spermidine putrescine transport system, permease component I
A361_14720	COG3842	ATPase activity
A361_14725	COG1840	ABC-type Fe3 transport system, periplasmic component
A361_14730	COG2188	Transcriptional regulator
A361_14740	COG0246	Mannitol dehydrogenase
A361_14745	COG3711	transcriptional antiterminator
A361_14750	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A361_14750	COG2213	PTS system mannitol-specific
A361_14770	COG0662	Cupin 2, conserved barrel domain protein
A361_14775	COG2801	Transposase and inactivated derivatives
A361_14800	COG1104	cysteine desulfurase activity
A361_14810	COG0346	lactoylglutathione lyase activity
A361_14840	COG0454	-acetyltransferase
A361_14855	COG0500	methyltransferase
A361_14880	COG2602	Beta-lactamase
A361_14885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A361_14895	COG3949	Membrane
A361_14900	COG4948	Mandelate Racemase Muconate Lactonizing
A361_14910	COG1473	amidohydrolase
A361_14935	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A361_14950	COG0254	rRNA binding
A361_14955	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A361_14960	COG3559	Exporter of polyketide antibiotics
A361_14965	COG1131	(ABC) transporter
A361_15005	COG3739	integral membrane protein
A361_15010	COG3655	Transcriptional regulator
A361_15080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A361_15090	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A361_15095	COG0778	Nitroreductase
A361_15135	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
A361_15160	COG1733	regulation of RNA biosynthetic process
A361_15165	COG1063	alcohol dehydrogenase
A361_15175	COG0833	amino acid
A361_15180	COG4187	Peptidase family M20/M25/M40
A361_15190	COG2235	arginine
A361_15195	COG1414	Transcriptional regulator
A361_15200	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A361_15205	COG0531	amino acid
A361_15210	COG1012	belongs to the aldehyde dehydrogenase family
A361_15215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A361_15240	COG1012	belongs to the aldehyde dehydrogenase family
A361_15245	COG0686	Belongs to the AlaDH PNT family
A361_15260	COG1131	(ABC) transporter
A361_15265	COG2205	protein histidine kinase activity
A361_15270	COG0745	RESPONSE REGULATOR receiver
A361_15290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A361_15310	COG0693	protein deglycase activity
A361_15350	COG0745	RESPONSE REGULATOR receiver
A361_15355	COG0515	serine threonine protein kinase
A361_15365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A361_15370	COG2318	DinB family
A361_15385	COG1404	Belongs to the peptidase S8 family
A361_15410	COG3227	Zinc metalloprotease (Elastase)
A361_15420	COG0561	phosphatase activity
A361_15425	COG1609	Transcriptional regulator
A361_15435	COG0697	spore germination
A361_15440	COG0583	DNA-binding transcription factor activity
A361_15450	COG0438	transferase activity, transferring glycosyl groups
A361_15450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A361_15455	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A361_15460	COG1136	(ABC) transporter
A361_15470	COG1309	transcriptional regulator
A361_15490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A361_15500	COG0346	lactoylglutathione lyase activity
A361_15505	COG1378	Sugar-specific transcriptional regulator TrmB
A361_15520	COG1012	belongs to the aldehyde dehydrogenase family
A361_15540	COG2423	ornithine cyclodeaminase activity
A361_15545	COG0006	proline dipeptidase activity
A361_15550	COG2508	Transcriptional regulator
A361_15555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A361_15565	COG2146	nitrite reductase [NAD(P)H] activity
A361_15580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A361_15585	COG2186	Transcriptional regulator
A361_15590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A361_15595	COG0402	S-adenosylhomocysteine deaminase activity
A361_15625	COG0702	epimerase
A361_15650	COG1028	Short-chain dehydrogenase reductase Sdr
A361_15675	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A361_15680	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A361_15685	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A361_15690	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A361_15695	COG0300	oxidoreductase activity
A361_15705	COG5002	protein histidine kinase activity
A361_15715	COG0656	L-ascorbic acid biosynthetic process
A361_15720	COG1028	Short-chain dehydrogenase reductase Sdr
A361_15725	COG0693	protein deglycase activity
A361_15735	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A361_15740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A361_15750	COG1063	alcohol dehydrogenase
A361_15755	COG5577	PFAM Coat F domain
A361_15775	COG1733	regulation of RNA biosynthetic process
A361_15780	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A361_15815	COG1607	acyl-coa hydrolase
A361_15820	COG0583	DNA-binding transcription factor activity
A361_15840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A361_15865	COG0006	proline dipeptidase activity
A361_15880	COG0145	ligase activity
A361_15885	COG0477	Major facilitator Superfamily
A361_15925	COG0145	ligase activity
A361_15935	COG0506	proline dehydrogenase activity
A361_15940	COG1012	belongs to the aldehyde dehydrogenase family
A361_15955	COG0109	protoheme IX farnesyltransferase activity
A361_15990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A361_15995	COG1621	beta-fructofuranosidase activity
A361_16000	COG1263	PTS System
A361_16000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A361_16005	COG1609	Transcriptional regulator
A361_16010	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
A361_16015	COG4145	pantothenate transmembrane transporter activity
A361_16035	COG2323	membrane
A361_16050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A361_16085	COG0823	Involved in the tonB-independent uptake of proteins
A361_16085	COG4946	Tricorn protease homolog
A361_16085	COG1506	peptidase
A361_16095	COG4948	Mandelate Racemase Muconate Lactonizing
A361_16100	COG4608	Belongs to the ABC transporter superfamily
A361_16105	COG0444	Belongs to the ABC transporter superfamily
A361_16160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A361_16165	COG0006	proline dipeptidase activity
A361_16175	COG1228	amidohydrolase
A361_16180	COG2508	Transcriptional regulator
A361_16190	COG1396	sequence-specific DNA binding
A361_16205	COG0788	formyltetrahydrofolate deformylase activity
A361_16210	COG3284	Transcriptional regulator
A361_16215	COG1063	alcohol dehydrogenase
A361_16220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A361_16225	COG0508	dehydrogenase complex catalyzes the overall conversion of
A361_16230	COG0022	dehydrogenase e1 component
A361_16235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A361_16255	COG1131	(ABC) transporter
A361_16260	COG2197	response regulator
A361_16265	COG4585	Histidine kinase
A361_16270	COG1595	DNA-templated transcription, initiation
A361_16275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A361_16370	COG2318	DinB family
A361_16420	COG1764	response to oxidative stress
A361_16425	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A361_16430	COG1959	2 iron, 2 sulfur cluster binding
A361_16450	COG1301	dicarboxylic acid transport
A361_16480	COG1657	PFAM Prenyltransferase squalene oxidase
A361_16485	COG1082	Xylose isomerase domain protein TIM barrel
A361_16495	COG0673	inositol 2-dehydrogenase activity
A361_16505	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A361_16510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A361_16515	COG4977	sequence-specific DNA binding
A361_16540	COG1757	Na H antiporter
A361_16545	COG1231	oxidoreductase activity
A361_16550	COG1193	negative regulation of DNA recombination
A361_16590	COG1940	carbohydrate kinase activity
A361_16600	COG0673	inositol 2-dehydrogenase activity
A361_16610	COG4608	Belongs to the ABC transporter superfamily
A361_16615	COG0444	Belongs to the ABC transporter superfamily
A361_16620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A361_16625	COG0601	transmembrane transport
A361_16630	COG0747	negative chemotaxis
A361_16635	COG5577	PFAM Coat F domain
A361_16645	COG3639	organic phosphonate transmembrane transporter activity
A361_16650	COG3639	organic phosphonate transmembrane transporter activity
A361_16655	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
A361_16665	COG4778	phosphonate C-P lyase system protein PhnL
A361_16670	COG3454	Phosphonate metabolism
A361_16675	COG4107	phosphonate C-P lyase system protein PhnK
A361_16680	COG3627	carbon phosphorus lyase activity
A361_16700	COG1609	Transcriptional regulator
A361_16710	COG0613	PHP domain protein
A361_16715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A361_16730	COG1349	DNA-binding transcription factor activity
A361_16740	COG1078	dGTPase activity
A361_16750	COG1366	Belongs to the anti-sigma-factor antagonist family
A361_16760	COG3403	YqcI/YcgG family
A361_16765	COG2323	membrane
A361_16780	COG2409	Drug exporters of the RND superfamily
A361_16790	COG5002	protein histidine kinase activity
A361_16790	COG3850	Histidine kinase
A361_16805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A361_16810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A361_16815	COG0640	Transcriptional regulator
A361_16835	COG0492	ferredoxin-NADP+ reductase activity
A361_16845	COG2076	Multidrug Resistance protein
A361_16850	COG2076	Multidrug Resistance protein
A361_16855	COG1309	transcriptional regulator
A361_16865	COG1028	Short-chain dehydrogenase reductase Sdr
A361_16875	COG2807	transmembrane transport
A361_16885	COG1595	DNA-templated transcription, initiation
A361_16900	COG0725	ABC transporter, periplasmic molybdate-binding protein
A361_16905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A361_16910	COG0697	spore germination
A361_16915	COG2855	membrane
A361_16920	COG0583	DNA-binding transcription factor activity
A361_16930	COG1228	amidohydrolase
A361_16935	COG1228	amidohydrolase
A361_16940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A361_16950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A361_16955	COG0686	Belongs to the AlaDH PNT family
A361_16965	COG0590	tRNA wobble adenosine to inosine editing
A361_16985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A361_17005	COG1231	oxidoreductase activity
A361_17010	COG1028	Short-chain dehydrogenase reductase Sdr
A361_17020	COG0726	polysaccharide deacetylase
A361_17035	COG2723	6-phospho-beta-galactosidase activity
A361_17050	COG2814	Major facilitator Superfamily
A361_17060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A361_17065	COG2304	oxidoreductase activity
A361_17070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A361_17095	COG1609	Transcriptional regulator
A361_17110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A361_17130	COG2814	Major facilitator Superfamily
A361_17135	COG1028	Short-chain dehydrogenase reductase Sdr
A361_17165	COG2514	catechol 2,3-dioxygenase activity
A361_17170	COG2259	Doxx family
A361_17175	COG1733	regulation of RNA biosynthetic process
A361_17180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A361_17185	COG1114	Component of the transport system for branched-chain amino acids
A361_17190	COG1802	Transcriptional regulator
A361_17205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A361_17210	COG1664	Polymer-forming cytoskeletal
A361_17215	COG0789	Transcriptional regulator
A361_17260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A361_17265	COG0569	domain protein
A361_17270	COG2356	endonuclease I
A361_17280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A361_17300	COG1301	dicarboxylic acid transport
A361_17305	COG0789	Transcriptional regulator
A361_17310	COG1253	flavin adenine dinucleotide binding
A361_17315	COG0586	Pfam SNARE associated Golgi protein
A361_17370	COG1595	DNA-templated transcription, initiation
A361_17375	COG5002	protein histidine kinase activity
A361_17385	COG0592	DNA-directed DNA polymerase activity
A361_17400	COG1357	PFAM Pentapeptide repeats (8 copies)
A361_17415	COG1131	(ABC) transporter
A361_17420	COG0842	Transport permease protein
A361_17445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A361_17460	COG1280	lysine exporter protein (LysE YggA)
A361_17485	COG1051	belongs to the nudix hydrolase family
A361_17495	COG0456	acetyltransferase
A361_17530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A361_17535	COG0583	DNA-binding transcription factor activity
A361_17550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A361_17570	COG2197	response regulator
A361_17575	COG0243	molybdopterin cofactor binding
A361_17595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A361_17615	COG1741	Belongs to the pirin family
A361_17620	COG0655	NAD(P)H dehydrogenase (quinone) activity
A361_17625	COG0400	carboxylic ester hydrolase activity
A361_17630	COG0346	lactoylglutathione lyase activity
A361_17635	COG1846	Transcriptional regulator
A361_17645	COG4149	molybdate abc transporter
A361_17655	COG0598	Magnesium transport protein CorA
A361_17675	COG0778	Nitroreductase
A361_17680	COG0456	acetyltransferase
A361_17705	COG5002	protein histidine kinase activity
A361_17710	COG0745	RESPONSE REGULATOR receiver
A361_17725	COG0534	Mate efflux family protein
A361_17735	COG3832	glyoxalase III activity
A361_17790	COG0322	excinuclease ABC activity
A361_17795	COG1183	phosphatidylcholine synthase activity
A361_17800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A361_17810	COG0183	Belongs to the thiolase family
A361_17815	COG1960	acyl-CoA dehydrogenase activity
A361_17825	COG1595	DNA-templated transcription, initiation
A361_17835	COG1131	(ABC) transporter
A361_17840	COG1725	Transcriptional regulator
A361_17845	COG1620	l-lactate permease
A361_17850	COG1414	Transcriptional regulator
A361_17855	COG0179	Fumarylacetoacetate (FAA) hydrolase
A361_17860	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A361_17865	COG0277	FAD linked oxidase domain protein
A361_17870	COG0247	lactate metabolic process
A361_17875	COG0277	FAD linked oxidase domain protein
A361_17880	COG2186	Transcriptional regulator
A361_17885	COG3883	PFAM NLP P60 protein
A361_17885	COG0791	NLP P60 protein
A361_17890	COG5609	conserved protein (DUF2294)
A361_17895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A361_17910	COG2427	Protein of unknown function (DUF1641)
A361_17915	COG3383	formate dehydrogenase (NAD+) activity
A361_17920	COG3226	Transcriptional regulator
A361_17940	COG0456	acetyltransferase
A361_17945	COG3153	acetyltransferase
A361_17945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A361_17960	COG1263	PTS System
A361_17960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A361_17965	COG3876	Protein conserved in bacteria
A361_17970	COG1472	Belongs to the glycosyl hydrolase 3 family
A361_17975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A361_17980	COG1132	(ABC) transporter
A361_17985	COG3610	response to peptide
A361_17990	COG2966	Psort location CytoplasmicMembrane, score
A361_17995	COG0789	Transcriptional regulator
A361_18000	COG1695	Transcriptional regulator
A361_18010	COG4585	Histidine kinase
A361_18020	COG2197	response regulator
A361_18030	COG2223	nitrite transmembrane transporter activity
A361_18060	COG0243	molybdopterin cofactor binding
A361_18115	COG2318	DinB family
A361_18120	COG2135	peptidase activity
A361_18130	COG2226	methyltransferase
A361_18140	COG1704	LemA family
A361_18185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A361_18185	COG0512	Glutamine amidotransferase of anthranilate synthase
A361_18195	COG2258	MOSC domain
A361_18200	COG2814	Major facilitator Superfamily
A361_18205	COG0596	Alpha beta hydrolase
A361_18230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A361_18230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A361_18230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A361_18235	COG1105	Belongs to the carbohydrate kinase PfkB family
A361_18240	COG1349	DNA-binding transcription factor activity
A361_18250	COG2234	aminopeptidase activity
A361_18260	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A361_18265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A361_18270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A361_18275	COG2217	Heavy metal translocating P-type atpase
A361_18280	COG2608	mercury ion transmembrane transporter activity
A361_18285	COG1937	Protein conserved in bacteria
A361_18295	COG1280	lysine exporter protein (LysE YggA)
A361_18345	COG0456	acetyltransferase
A361_18355	COG1278	Cold shock
A361_18360	COG0513	Belongs to the DEAD box helicase family
A361_18365	COG1278	Cold shock
A361_18370	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A361_18385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A361_18395	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A361_18400	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A361_18405	COG0671	phosphoesterase, PA-phosphatase related
A361_18410	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
A361_18415	COG3285	dna ligase
A361_18415	COG1793	dna ligase
A361_18420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A361_18435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A361_18440	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A361_18440	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A361_18445	COG0307	riboflavin synthase, alpha
A361_18450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A361_18450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A361_18455	COG2217	Heavy metal translocating P-type atpase
A361_18460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A361_18475	COG4667	esterase of the alpha-beta hydrolase superfamily
A361_18480	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A361_18485	COG1131	(ABC) transporter
A361_18510	COG0586	Pfam SNARE associated Golgi protein
A361_18515	COG0402	S-adenosylhomocysteine deaminase activity
A361_18525	COG0534	Mate efflux family protein
A361_18530	COG1028	Short-chain dehydrogenase reductase Sdr
A361_18550	COG2340	Cysteine-rich secretory protein family
A361_18560	COG5002	protein histidine kinase activity
A361_18565	COG0745	RESPONSE REGULATOR receiver
A361_18590	COG0523	cobalamin synthesis protein
A361_18600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A361_18605	COG1316	TRANSCRIPTIONal
A361_18610	COG0793	Belongs to the peptidase S41A family
A361_18610	COG3409	Peptidoglycan-binding domain 1 protein
A361_18615	COG2608	mercury ion transmembrane transporter activity
A361_18625	COG1876	peptidase activity
A361_18640	COG0584	glycerophosphoryl diester phosphodiesterase
A361_18645	COG4326	sporulation control protein
A361_18655	COG4479	Belongs to the UPF0346 family
A361_18665	COG1509	lysine 2,3-aminomutase activity
A361_18670	COG3829	transcription factor binding
A361_18675	COG0456	acetyltransferase
A361_18680	COG1012	belongs to the aldehyde dehydrogenase family
A361_18685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A361_18690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A361_18695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A361_18700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A361_18705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A361_18715	COG1619	proteins homologs of microcin C7 resistance protein MccF
A361_18740	COG2190	(PTS) system
A361_18745	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A361_18750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A361_18770	COG2755	lipolytic protein G-D-S-L family
A361_18775	COG1999	signal sequence binding
A361_18785	COG5002	protein histidine kinase activity
A361_18790	COG1307	EDD domain protein, DegV family
A361_18800	COG0805	protein transport
A361_18805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A361_18810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A361_18820	COG0204	Acyl-transferase
A361_18825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A361_18840	COG2310	stress, protein
A361_18845	COG3853	Toxic anion resistance protein (TelA)
A361_18880	COG0861	Integral membrane protein TerC family
A361_18885	COG2310	stress, protein
A361_18895	COG0436	Aminotransferase
A361_18900	COG2136	Putative SAM-dependent methyltransferase
A361_18900	COG2521	methyltransferase
A361_18910	COG0129	dihydroxy-acid dehydratase activity
A361_18915	COG1413	lyase activity
A361_18920	COG0488	(ABC) transporter
A361_18925	COG1418	mRNA catabolic process
A361_18930	COG1307	EDD domain protein, DegV family
A361_18965	COG1073	alpha beta
A361_18965	COG2226	methyltransferase
A361_18975	COG1321	iron dependent repressor
A361_18985	COG1523	belongs to the glycosyl hydrolase 13 family
A361_19000	COG1278	Cold shock
A361_19005	COG0328	RNA-DNA hybrid ribonuclease activity
A361_19010	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A361_19015	COG0328	RNA-DNA hybrid ribonuclease activity
A361_19030	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A361_19045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A361_19070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A361_19075	COG1755	Isoprenylcysteine carboxyl methyltransferase
A361_19080	COG3424	synthase
A361_19085	COG2233	PERMEase
A361_19090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A361_19100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A361_19105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A361_19110	COG0697	spore germination
A361_19115	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A361_19140	COG2151	metal-sulfur cluster biosynthetic enzyme
A361_19145	COG1199	ATP-dependent helicase activity
A361_19150	COG0116	Belongs to the methyltransferase superfamily
A361_19160	COG3599	regulation of cell shape
A361_19165	COG4474	Belongs to the UPF0398 family
A361_19175	COG3359	exonuclease
A361_19180	COG1205	dead DEAH box helicase
A361_19180	COG1111	helicase
A361_19195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A361_19205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A361_19210	COG0601	transmembrane transport
A361_19245	COG3331	DNA recombination
A361_19250	COG4499	WXG100 protein secretion system (Wss), protein YukC
A361_19250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A361_19255	COG2801	Transposase and inactivated derivatives
A361_19270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A361_19275	COG3935	DnaD domain protein
A361_19280	COG0017	Asparaginyl-tRNA synthetase
A361_19300	COG1199	ATP-dependent helicase activity
A361_19300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A361_19305	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
A361_19310	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A361_19315	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A361_19330	COG0438	transferase activity, transferring glycosyl groups
A361_19335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A361_19340	COG1803	Methylglyoxal synthase
A361_19345	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A361_19350	COG1694	Mazg nucleotide pyrophosphohydrolase
A361_19355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A361_19370	COG2738	Putative neutral zinc metallopeptidase
A361_19390	COG4347	Protein of unknown function (DUF1405)
A361_19400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A361_19420	COG0457	Tetratricopeptide repeat
A361_19430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A361_19435	COG0287	Prephenate dehydrogenase
A361_19440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A361_19445	COG4401	Chorismate mutase type I
A361_19450	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A361_19455	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A361_19460	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A361_19465	COG0105	UTP biosynthetic process
A361_19470	COG0142	geranyltranstransferase activity
A361_19490	COG0302	gtp cyclohydrolase
A361_19495	COG0776	regulation of translation
A361_19500	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A361_19515	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A361_19520	COG1160	GTP binding
A361_19550	COG0539	negative regulation of cytoplasmic translation
A361_19560	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A361_19575	COG2959	enzyme of heme biosynthesis
A361_19580	COG3773	Cell wall hydrolase
A361_19580	COG3409	Peptidoglycan-binding domain 1 protein
A361_19585	COG2339	peptidase activity
A361_19590	COG0252	asparaginase activity
A361_19595	COG0492	ferredoxin-NADP+ reductase activity
A361_19600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A361_19605	COG4862	establishment of competence for transformation
A361_19615	COG1408	metallophosphoesterase
A361_19640	COG3546	catalase activity
A361_19655	COG1266	CAAX protease self-immunity
A361_19660	COG0514	ATP-dependent DNA helicase (RecQ)
A361_19665	COG4955	Helix-turn-helix domain
A361_19675	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A361_19680	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A361_19685	COG1196	nuclear chromosome segregation
A361_19685	COG0739	heme binding
A361_19685	COG0741	lytic transglycosylase activity
A361_19695	COG1595	DNA-templated transcription, initiation
A361_19700	COG5002	protein histidine kinase activity
A361_19705	COG0745	RESPONSE REGULATOR receiver
A361_19710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A361_19715	COG1333	cytochrome c biogenesis protein
A361_19720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A361_19725	COG1187	pseudouridine synthase activity
A361_19730	COG0700	Nucleoside recognition
A361_19735	COG2715	membrane protein required for spore maturation
A361_19740	COG1686	Belongs to the peptidase S11 family
A361_19745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A361_19760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A361_19775	COG1547	Domain of unknown function (DUF309)
A361_19785	COG4086	secreted protein
A361_19795	COG0697	spore germination
A361_19820	COG2172	sigma factor antagonist activity
A361_19830	COG1686	Belongs to the peptidase S11 family
A361_19845	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A361_19850	COG4974	Belongs to the 'phage' integrase family
A361_19865	COG0735	belongs to the Fur family
A361_19870	COG1300	Membrane
A361_19880	COG1379	DNA repair
A361_19890	COG0667	Aldo Keto reductase
A361_19905	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A361_19910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A361_19920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A361_19925	COG1073	alpha beta
A361_19950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A361_19965	COG2801	Transposase and inactivated derivatives
A361_19970	COG0300	oxidoreductase activity
A361_19975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A361_19980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A361_19985	COG1215	transferase activity, transferring glycosyl groups
A361_19990	COG1902	pentaerythritol trinitrate reductase activity
A361_20000	COG0733	neurotransmitter:sodium symporter activity
A361_20010	COG1234	tRNA 3'-trailer cleavage
A361_20015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A361_20020	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A361_20025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A361_20035	COG2195	Cleaves the N-terminal amino acid of tripeptides
A361_20040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A361_20045	COG0346	lactoylglutathione lyase activity
A361_20050	COG1376	ErfK ybiS ycfS ynhG family protein
A361_20055	COG4129	membrane
A361_20060	COG1126	abc transporter atp-binding protein
A361_20065	COG0765	amino acid transport
A361_20070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A361_20080	COG1703	isobutyryl-CoA mutase activity
A361_20085	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A361_20085	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A361_20095	COG0508	dehydrogenase complex catalyzes the overall conversion of
A361_20100	COG0022	dehydrogenase e1 component
A361_20105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A361_20110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A361_20125	COG0280	phosphate acetyltransferase
A361_20130	COG3290	protein histidine kinase activity
A361_20130	COG3829	transcription factor binding
A361_20140	COG0745	RESPONSE REGULATOR receiver
A361_20145	COG0750	zinc metalloprotease
A361_20150	COG0497	DNA recombination
A361_20160	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A361_20165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A361_20175	COG1722	exodeoxyribonuclease VII activity
A361_20185	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A361_20195	COG1302	Protein conserved in bacteria
A361_20200	COG0439	Biotin carboxylase
A361_20205	COG0511	ligase activity, forming carbon-carbon bonds
A361_20245	COG3854	ATPases associated with a variety of cellular activities
A361_20250	COG1785	Belongs to the alkaline phosphatase family
A361_20260	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A361_20265	COG0006	proline dipeptidase activity
A361_20270	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A361_20290	COG1752	Esterase of the alpha-beta hydrolase superfamily
A361_20300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A361_20305	COG0095	Lipoate-protein ligase
A361_20310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_20315	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A361_20320	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A361_20325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A361_20330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A361_20370	COG4537	Required for transformation and DNA binding
A361_20375	COG1459	type II secretion system
A361_20380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A361_20385	COG2385	sporulation resulting in formation of a cellular spore
A361_20420	COG1695	Transcriptional regulator
A361_20425	COG1595	DNA-templated transcription, initiation
A361_20495	COG2856	Zn peptidase
A361_20500	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A361_20595	COG0406	alpha-ribazole phosphatase activity
A361_20610	COG3706	GGDEF domain
A361_20610	COG5001	Diguanylate cyclase
A361_20610	COG4251	negative regulation of phosphorylation
A361_20610	COG2203	Gaf domain
A361_20655	COG2226	methyltransferase
A361_20790	COG1393	Belongs to the ArsC family
A361_20810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A361_20820	COG0011	TIGRFAM Protein of
A361_20835	COG1940	carbohydrate kinase activity
A361_20845	COG0697	spore germination
A361_20850	COG0457	Tetratricopeptide repeat
A361_20850	COG0705	Rhomboid family
A361_20870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A361_20900	COG0704	Plays a role in the regulation of phosphate uptake
A361_20905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A361_20910	COG0581	inorganic phosphate transmembrane transporter activity
A361_20915	COG0573	inorganic phosphate transmembrane transporter activity
A361_20920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A361_20930	COG0477	Major facilitator Superfamily
A361_20940	COG2839	Protein conserved in bacteria
A361_20945	COG1283	sodium-dependent phosphate transmembrane transporter activity
A361_20950	COG5521	maltodextrose utilization protein MalA
A361_20965	COG2801	Transposase and inactivated derivatives
A361_20975	COG4709	membrane
A361_20980	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
A361_20985	COG0735	belongs to the Fur family
A361_20990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A361_20995	COG1121	(ABC) transporter
A361_21005	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A361_21010	COG0513	Belongs to the DEAD box helicase family
A361_21020	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A361_21025	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A361_21030	COG2384	SAM-dependent methyltransferase
A361_21035	COG2010	Cytochrome c
A361_21040	COG1960	acyl-CoA dehydrogenase activity
A361_21050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A361_21055	COG0358	DNA primase activity
A361_21060	COG1671	Belongs to the UPF0178 family
A361_21070	COG0517	IMP dehydrogenase activity
A361_21075	COG0751	glycine-tRNA ligase activity
A361_21080	COG0752	glycyl-tRNA synthetase alpha subunit
A361_21085	COG1381	Involved in DNA repair and RecF pathway recombination
A361_21090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A361_21095	COG0295	cytidine deaminase activity
A361_21100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A361_21110	COG1480	7TM receptor with intracellular HD hydrolase
A361_21115	COG1702	phosphate starvation-inducible protein PhoH
A361_21135	COG4864	UPF0365 protein
A361_21140	COG1030	water channel activity
A361_21145	COG1610	YqeY-like protein
A361_21150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A361_21155	COG1283	sodium-dependent phosphate transmembrane transporter activity
A361_21160	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A361_21165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A361_21170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A361_21175	COG2264	protein methyltransferase activity
A361_21180	COG0484	heat shock protein binding
A361_21190	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A361_21200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A361_21210	COG0481	GTPase activity
A361_21220	COG0860	N-Acetylmuramoyl-L-alanine amidase
A361_21230	COG0268	Binds directly to 16S ribosomal RNA
A361_21235	COG1466	dna polymerase III delta subunit
A361_21240	COG0658	competence protein
A361_21240	COG2333	competence protein COMEC
A361_21245	COG2131	deaminase
A361_21250	COG1555	photosystem II stabilization
A361_21250	COG1596	polysaccharide export
A361_21255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A361_21260	COG2226	methyltransferase
A361_21265	COG0799	negative regulation of ribosome biogenesis
A361_21270	COG1713	HD superfamily hydrolase involved in NAD metabolism
A361_21275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A361_21280	COG1534	Rna-binding protein
A361_21290	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A361_21295	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A361_21310	COG1183	phosphatidylcholine synthase activity
A361_21335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A361_21350	COG0768	penicillin binding
A361_21355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A361_21360	COG0572	uridine kinase
A361_21380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A361_21385	COG3906	Belongs to the UPF0473 family
A361_21395	COG4472	Bacterial protein of unknown function (DUF965)
A361_21405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A361_21410	COG0628	permease
A361_21420	COG3881	PFAM PRC-barrel domain
A361_21425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A361_21440	COG1104	cysteine desulfurase activity
A361_21445	COG1959	2 iron, 2 sulfur cluster binding
A361_21450	COG2364	Membrane
A361_21455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A361_21460	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A361_21465	COG1131	(ABC) transporter
A361_21475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A361_21485	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A361_21490	COG0124	histidyl-tRNA synthetase
A361_21500	COG3103	Sh3 type 3 domain protein
A361_21500	COG4991	sh3 domain protein
A361_21500	COG0860	N-Acetylmuramoyl-L-alanine amidase
A361_21505	COG1490	D-aminoacyl-tRNA deacylase activity
A361_21510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A361_21515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A361_21520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A361_21520	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A361_21525	COG5416	Lipopolysaccharide assembly protein A domain
A361_21530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A361_21535	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A361_21535	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A361_21545	COG2244	polysaccharide biosynthetic process
A361_21550	COG2323	membrane
A361_21555	COG1862	Preprotein translocase
A361_21565	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A361_21585	COG0582	viral genome integration into host DNA
A361_21605	COG1388	LysM domain
A361_21615	COG0157	Belongs to the NadC ModD family
A361_21620	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A361_21625	COG1104	cysteine desulfurase activity
A361_21630	COG1827	regulation of RNA biosynthetic process
A361_21635	COG0077	Prephenate dehydratase
A361_21640	COG4492	Belongs to the UPF0735 family
A361_21645	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A361_21650	COG3290	protein histidine kinase activity
A361_21655	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A361_21660	COG2868	ribosomal protein
A361_21665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A361_21670	COG1530	ribonuclease E activity
A361_21675	COG1994	Peptidase M50
A361_21680	COG0739	heme binding
A361_21685	COG2894	cell division
A361_21700	COG1792	Involved in formation and maintenance of cell shape
A361_21705	COG1077	Cell shape determining protein MreB Mrl
A361_21710	COG2003	Belongs to the UPF0758 family
A361_21715	COG0424	maF-like protein
A361_21725	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A361_21730	COG3706	GGDEF domain
A361_21730	COG0745	RESPONSE REGULATOR receiver
A361_21735	COG0285	dihydrofolate synthase activity
A361_21740	COG0525	valine-tRNA ligase activity
A361_21755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A361_21760	COG1388	LysM domain
A361_21760	COG1388	LysM domain
A361_21765	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A361_21770	COG0113	porphobilinogen synthase activity
A361_21780	COG0181	hydroxymethylbilane synthase activity
A361_21785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A361_21805	COG1126	abc transporter atp-binding protein
A361_21810	COG0765	amino acid transport
A361_21825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A361_21830	COG0470	DNA polymerase III
A361_21830	COG1067	ATP-dependent peptidase activity
A361_21835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A361_21840	COG0544	peptidyl-prolyl cis-trans isomerase activity
A361_21845	COG1477	protein flavinylation
A361_21845	COG0457	Tetratricopeptide repeat
A361_21850	COG0066	3-isopropylmalate dehydratase activity
A361_21855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A361_21860	COG0473	3-isopropylmalate dehydrogenase activity
A361_21865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A361_21870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A361_21875	COG0440	acetolactate synthase activity
A361_21880	COG0028	Belongs to the TPP enzyme family
A361_21890	COG0622	Phosphoesterase
A361_21895	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A361_21905	COG5401	PFAM Sporulation and spore germination
A361_21910	COG0514	ATP-dependent DNA helicase (RecQ)
A361_21920	COG1846	Transcriptional regulator
A361_21925	COG2197	response regulator
A361_21930	COG0824	Thioesterase
A361_21935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A361_21940	COG1053	succinate dehydrogenase
A361_21945	COG2009	succinate dehydrogenase
A361_21950	COG1719	4-vinyl reductase, 4VR
A361_21960	COG0322	excinuclease ABC activity
A361_21965	COG3118	belongs to the thioredoxin family
A361_21970	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A361_21975	COG2086	electron transfer activity
A361_21980	COG1024	Enoyl-CoA hydratase
A361_21985	COG1309	transcriptional regulator
A361_21995	COG0318	PFAM AMP-dependent synthetase and ligase
A361_22000	COG3766	membrane
A361_22010	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A361_22010	COG1796	DNA polymerase
A361_22015	COG1286	toxin biosynthetic process
A361_22020	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
A361_22030	COG0072	phenylalanine-tRNA ligase activity
A361_22030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A361_22035	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A361_22040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A361_22050	COG1363	Peptidase, m42
A361_22070	COG3326	Membrane
A361_22075	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A361_22085	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A361_22090	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A361_22100	COG1484	DNA-dependent DNA replication
A361_22105	COG3611	Membrane attachment protein
A361_22110	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A361_22120	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A361_22125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A361_22130	COG0237	dephospho-CoA kinase activity
A361_22135	COG1971	Probably functions as a manganese efflux pump
A361_22140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A361_22145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A361_22145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A361_22150	COG0330	HflC and HflK could
A361_22155	COG0330	HflC and HflK could
A361_22160	COG5002	protein histidine kinase activity
A361_22165	COG0745	RESPONSE REGULATOR receiver
A361_22175	COG0039	L-malate dehydrogenase activity
A361_22180	COG0538	isocitrate dehydrogenase activity
A361_22185	COG0372	Belongs to the citrate synthase family
A361_22195	COG2707	UPF0756 membrane protein
A361_22200	COG0628	permease
A361_22215	COG0205	6-phosphofructokinase activity
A361_22220	COG0825	malonyl-CoA metabolic process
A361_22225	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A361_22235	COG0281	malic enzyme
A361_22240	COG0587	DNA-directed DNA polymerase activity
A361_22255	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A361_22265	COG4109	DRTGG domain
A361_22275	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A361_22280	COG0006	proline dipeptidase activity
A361_22290	COG0589	response to stress
A361_22295	COG0165	Argininosuccinate lyase
A361_22300	COG0137	argininosuccinate synthase activity
A361_22305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A361_22315	COG0521	Mo-molybdopterin cofactor biosynthetic process
A361_22325	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A361_22330	COG0827	DNA restriction-modification system
A361_22335	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A361_22340	COG3874	Sporulation protein YtfJ
A361_22350	COG1714	RDD family
A361_22355	COG0616	signal peptide processing
A361_22360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A361_22365	COG2962	Rard protein
A361_22370	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A361_22375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A361_22385	COG0301	tRNA thio-modification
A361_22390	COG1104	cysteine desulfurase activity
A361_22395	COG1114	Component of the transport system for branched-chain amino acids
A361_22400	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
A361_22405	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A361_22410	COG1309	transcriptional regulator
A361_22415	COG1956	GAF domain-containing protein
A361_22420	COG0626	cystathionine gamma-synthase activity
A361_22425	COG2203	Gaf domain
A361_22425	COG2199	diguanylate cyclase activity
A361_22430	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A361_22445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A361_22450	COG0454	-acetyltransferase
A361_22455	COG0517	IMP dehydrogenase activity
A361_22460	COG0123	including yeast histone deacetylase and acetoin utilization protein
A361_22480	COG1605	Chorismate mutase
A361_22480	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A361_22490	COG3118	belongs to the thioredoxin family
A361_22495	COG4980	gas vesicle protein
A361_22500	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
A361_22505	COG2309	aminopeptidase activity
A361_22510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A361_22525	COG1674	ftsk spoiiie
A361_22530	COG4848	Belongs to the UPF0354 family
A361_22535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A361_22555	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
A361_22560	COG1363	Peptidase, m42
A361_22565	COG5584	Small secreted protein
A361_22570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A361_22575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A361_22585	COG0510	thiamine kinase activity
A361_22590	COG1523	belongs to the glycosyl hydrolase 13 family
A361_22595	COG1597	lipid kinase activity
A361_22610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A361_22620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A361_22625	COG4473	ABC transporter
A361_22630	COG1131	(ABC) transporter
A361_22640	COG1349	DNA-binding transcription factor activity
A361_22645	COG1187	pseudouridine synthase activity
A361_22655	COG2244	polysaccharide biosynthetic process
A361_22660	COG2081	HI0933 family
A361_22670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_22675	COG0495	leucyl-tRNA aminoacylation
A361_22680	COG1028	Short-chain dehydrogenase reductase Sdr
A361_22685	COG2610	gluconate transmembrane transporter activity
A361_22700	COG2814	Major facilitator Superfamily
A361_22720	COG1242	4 iron, 4 sulfur cluster binding
A361_22725	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A361_22735	COG2267	carboxylic ester hydrolase activity
A361_22740	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A361_22745	COG4990	cell redox homeostasis
A361_22750	COG0367	asparagine synthase
A361_22755	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A361_22775	COG1506	peptidase
A361_22780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A361_22785	COG1116	anion transmembrane transporter activity
A361_22790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A361_22795	COG0494	nUDIX hydrolase
A361_22815	COG0783	Belongs to the Dps family
A361_22825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A361_22830	COG1854	S-ribosylhomocysteine lyase activity
A361_22835	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A361_22840	COG0288	reversible hydration of carbon dioxide
A361_22850	COG1271	oxidase subunit
A361_22855	COG1294	oxidase, subunit
A361_22860	COG4948	Mandelate Racemase Muconate Lactonizing
A361_22870	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A361_22875	COG0596	Alpha beta hydrolase
A361_22880	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
A361_22885	COG1169	isochorismate synthase
A361_22890	COG1575	Belongs to the MenA family. Type 1 subfamily
A361_22900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A361_22910	COG1834	amidinotransferase
A361_22915	COG0058	SHG alpha-glucan phosphorylase activity
A361_22920	COG0297	glycogen (starch) synthase activity
A361_22925	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A361_23070	COG1285	pathogenesis
A361_23080	COG2318	DinB family
A361_23090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A361_23140	COG1132	(ABC) transporter
A361_23175	COG5434	Belongs to the glycosyl hydrolase 28 family
A361_23180	COG3420	alginic acid biosynthetic process
A361_23180	COG5434	Belongs to the glycosyl hydrolase 28 family
A361_23205	COG1442	glycosyl transferase family 8
A361_23205	COG1216	Glycosyl transferase, family 2
A361_23215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A361_23220	COG0110	maltose O-acetyltransferase activity
A361_23225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A361_23240	COG0438	transferase activity, transferring glycosyl groups
A361_23250	COG1215	transferase activity, transferring glycosyl groups
A361_23255	COG0438	transferase activity, transferring glycosyl groups
A361_23260	COG0438	transferase activity, transferring glycosyl groups
A361_23265	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A361_23270	COG1086	Polysaccharide biosynthesis protein
A361_23275	COG0489	protein tyrosine kinase activity
A361_23280	COG3944	biosynthesis protein
A361_23285	COG1132	(ABC) transporter
A361_23320	COG0745	RESPONSE REGULATOR receiver
A361_23320	COG2972	Histidine kinase
A361_23325	COG3279	Response regulator of the LytR AlgR family
A361_23345	COG0784	Response regulator, receiver
A361_23350	COG5001	Diguanylate cyclase
A361_23355	COG1294	oxidase, subunit
A361_23360	COG1271	oxidase subunit
A361_23365	COG0702	epimerase
A361_23370	COG2112	serine threonine protein kinase
A361_23380	COG2936	dipeptidyl-peptidase activity
A361_23385	COG2234	aminopeptidase activity
A361_23390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A361_23410	COG1979	alcohol dehydrogenase
A361_23420	COG2155	Conserved Protein
A361_23425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A361_23430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A361_23435	COG1012	belongs to the aldehyde dehydrogenase family
A361_23440	COG3829	transcription factor binding
A361_23455	COG1098	S1 RNA binding domain
A361_23465	COG0436	Aminotransferase
A361_23470	COG1522	sequence-specific DNA binding
A361_23475	COG2267	carboxylic ester hydrolase activity
A361_23485	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A361_23500	COG2032	superoxide dismutase activity
A361_23510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A361_23520	COG5018	Exonuclease
A361_23525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A361_23545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A361_23545	COG2111	Na H antiporter
A361_23550	COG2111	Na H antiporter
A361_23555	COG1006	Multisubunit Na H antiporter MnhC subunit
A361_23560	COG0651	ATP synthesis coupled electron transport
A361_23565	COG1863	multisubunit Na H antiporter MnhE subunit
A361_23570	COG2212	antiporter activity
A361_23575	COG1320	monovalent cation:proton antiporter activity
A361_23580	COG2050	protein possibly involved in aromatic compounds catabolism
A361_23610	COG0686	Belongs to the AlaDH PNT family
A361_23615	COG2508	Transcriptional regulator
A361_23615	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A361_23620	COG1115	amino acid carrier protein
A361_23630	COG1028	Short-chain dehydrogenase reductase Sdr
A361_23640	COG3243	poly(R)-hydroxyalkanoic acid synthase
A361_23645	COG0671	phosphoesterase, PA-phosphatase related
A361_23650	COG0789	Transcriptional regulator
A361_23655	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A361_23660	COG2056	Na+-H+ antiporter family
A361_23665	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A361_23680	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A361_23690	COG3584	3D domain protein
A361_23700	COG0494	nUDIX hydrolase
A361_23705	COG1252	NADH dehydrogenase
A361_23715	COG0316	Belongs to the HesB IscA family
A361_23725	COG4844	belongs to the
A361_23730	COG1252	NADH dehydrogenase
A361_23735	COG4837	Protein of unknown function (DUF1462)
A361_23740	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A361_23745	COG0083	homoserine kinase activity
A361_23750	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A361_23755	COG0460	homoserine dehydrogenase
A361_23760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A361_23765	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A361_23770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A361_23775	COG0647	UMP catabolic process
A361_23780	COG1349	DNA-binding transcription factor activity
A361_23785	COG2445	Protein of unknown function DUF86
A361_23790	COG3300	MHYT domain
A361_23790	COG5001	Diguanylate cyclase
A361_23805	COG4470	Protein conserved in bacteria
A361_23820	COG2801	Transposase and inactivated derivatives
A361_23830	COG0739	heme binding
A361_23835	COG0733	neurotransmitter:sodium symporter activity
A361_23840	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
A361_23845	COG1757	Na H antiporter
A361_23860	COG3377	Domain of unknown function (DUF1805)
A361_23865	COG1801	Protein of unknown function DUF72
A361_23870	COG0719	Fe-S assembly protein
A361_23875	COG0822	iron-sulfur transferase activity
A361_23880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A361_23885	COG0719	Fe-S assembly protein
A361_23890	COG0396	ATPase activity
A361_23895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A361_23900	COG1464	Belongs to the NlpA lipoprotein family
A361_23905	COG2011	ABC-type metal ion transport system permease component
A361_23910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A361_23930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A361_23935	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A361_23945	COG0509	glycine decarboxylation via glycine cleavage system
A361_23950	COG1393	Belongs to the ArsC family
A361_23955	COG1960	acyl-CoA dehydrogenase activity
A361_23960	COG0183	Belongs to the thiolase family
A361_23965	COG1250	3-hydroxyacyl-CoA dehydrogenase
A361_23965	COG1024	Enoyl-CoA hydratase
A361_23990	COG1120	ATPase activity
A361_23995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A361_24000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A361_24005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A361_24025	COG0772	Belongs to the SEDS family
A361_24045	COG0860	N-Acetylmuramoyl-L-alanine amidase
A361_24055	COG1028	Short-chain dehydrogenase reductase Sdr
A361_24065	COG1126	abc transporter atp-binding protein
A361_24070	COG0765	amino acid transport
A361_24075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A361_24090	COG0242	peptide deformylase activity
A361_24115	COG4990	cell redox homeostasis
A361_24120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A361_24125	COG0300	oxidoreductase activity
A361_24130	COG1033	growth of symbiont in host cell
A361_24130	COG2409	Drug exporters of the RND superfamily
A361_24135	COG1846	Transcriptional regulator
A361_24145	COG1785	Belongs to the alkaline phosphatase family
A361_24150	COG0655	NAD(P)H dehydrogenase (quinone) activity
A361_24155	COG0668	transmembrane transport
A361_24160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A361_24165	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A361_24180	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A361_24185	COG0557	exoribonuclease II activity
A361_24190	COG1647	Serine aminopeptidase, S33
A361_24195	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A361_24215	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A361_24245	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A361_24260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A361_24265	COG1481	regulation of sporulation
A361_24270	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A361_24275	COG1660	Displays ATPase and GTPase activities
A361_24280	COG1051	belongs to the nudix hydrolase family
A361_24285	COG0492	ferredoxin-NADP+ reductase activity
A361_24290	COG0457	Tetratricopeptide repeat
A361_24300	COG1115	amino acid carrier protein
A361_24305	COG1012	belongs to the aldehyde dehydrogenase family
A361_24310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A361_24315	COG3938	Belongs to the proline racemase family
A361_24320	COG3938	Belongs to the proline racemase family
A361_24325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A361_24330	COG3829	transcription factor binding
A361_24330	COG3290	protein histidine kinase activity
A361_24350	COG0140	phosphoribosyl-ATP diphosphatase activity
A361_24350	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A361_24355	COG0107	imidazoleglycerol-phosphate synthase activity
A361_24360	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A361_24365	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A361_24370	COG0131	Imidazoleglycerol-phosphate dehydratase
A361_24375	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A361_24380	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A361_24385	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
A361_24390	COG0110	maltose O-acetyltransferase activity
A361_24400	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A361_24405	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A361_24410	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
A361_24415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A361_24415	COG1263	PTS System
A361_24425	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A361_24430	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A361_24435	COG0363	glucosamine-6-phosphate deaminase activity
A361_24450	COG1950	PFAM Membrane protein of
A361_24460	COG3595	metallopeptidase activity
A361_24480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A361_24485	COG0556	nucleotide-excision repair
A361_24490	COG4897	Protein conserved in bacteria
A361_24505	COG1464	Belongs to the NlpA lipoprotein family
A361_24510	COG2011	ABC-type metal ion transport system permease component
A361_24515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A361_24520	COG0697	spore germination
A361_24525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A361_24530	COG4191	Histidine kinase
A361_24540	COG0628	permease
A361_24555	COG0154	amidase activity
A361_24565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A361_24570	COG0596	Alpha beta hydrolase
A361_24575	COG2814	Major facilitator Superfamily
A361_24580	COG2239	Acts as a magnesium transporter
A361_24590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A361_24595	COG3409	Peptidoglycan-binding domain 1 protein
A361_24595	COG0793	Belongs to the peptidase S41A family
A361_24605	COG3883	PFAM NLP P60 protein
A361_24605	COG0791	NLP P60 protein
A361_24610	COG2177	Part of the ABC transporter FtsEX involved in
A361_24615	COG2884	Cell division ATP-binding protein ftsE
A361_24625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A361_24635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A361_24640	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A361_24645	COG0653	protein targeting
A361_24655	COG1405	negative regulation of cell septum assembly
A361_24655	COG3012	SEC-C Motif Domain Protein
A361_24660	COG2059	Chromate
A361_24665	COG2059	Chromate
A361_24690	COG0840	transmembrane signaling receptor activity
A361_24715	COG1516	flagellar protein fliS
A361_24720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A361_24725	COG1334	flagellar protein FlaG
A361_24740	COG2801	Transposase and inactivated derivatives
A361_24745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A361_24750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A361_24755	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A361_24760	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
A361_24770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A361_24775	COG4786	Flagellar basal body rod
A361_24775	COG1256	bacterial-type flagellum assembly
A361_24795	COG5001	Diguanylate cyclase
A361_24800	COG1040	competence protein
A361_24805	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A361_24810	COG1307	EDD domain protein, DegV family
A361_24820	COG2197	response regulator
A361_24825	COG4585	Histidine kinase
A361_24830	COG1739	Uncharacterized protein family UPF0029
A361_24835	COG1316	TRANSCRIPTIONal
A361_24845	COG3307	-O-antigen
A361_24895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A361_24900	COG2247	cell wall binding repeat
A361_24900	COG0860	N-Acetylmuramoyl-L-alanine amidase
A361_24905	COG2247	cell wall binding repeat
A361_24905	COG0860	N-Acetylmuramoyl-L-alanine amidase
A361_24910	COG0860	N-Acetylmuramoyl-L-alanine amidase
A361_24910	COG2247	cell wall binding repeat
A361_24915	COG2385	sporulation resulting in formation of a cellular spore
A361_24915	COG2247	cell wall binding repeat
A361_24920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A361_24930	COG1316	TRANSCRIPTIONal
A361_24935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A361_24940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A361_24960	COG0438	transferase activity, transferring glycosyl groups
A361_24965	COG1215	transferase activity, transferring glycosyl groups
A361_24980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A361_24985	COG1216	Glycosyl transferase, family 2
A361_24990	COG1404	Belongs to the peptidase S8 family
A361_25000	COG1316	TRANSCRIPTIONal
A361_25050	COG0791	NLP P60 protein
A361_25050	COG1388	LysM domain
A361_25070	COG0768	penicillin binding
A361_25080	COG0473	3-isopropylmalate dehydrogenase activity
A361_25085	COG1028	Short-chain dehydrogenase reductase Sdr
A361_25100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A361_25105	COG0183	Belongs to the thiolase family
A361_25110	COG1960	acyl-CoA dehydrogenase activity
A361_25115	COG1024	Enoyl-CoA hydratase
A361_25120	COG1250	3-hydroxyacyl-CoA dehydrogenase
A361_25135	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A361_25140	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A361_25150	COG3290	protein histidine kinase activity
A361_25150	COG3829	transcription factor binding
A361_25155	COG3037	sugar-specific permease SgaT UlaA
A361_25165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A361_25175	COG0165	Argininosuccinate lyase
A361_25185	COG3842	ATPase activity
A361_25190	COG1840	ABC-type Fe3 transport system, periplasmic component
A361_25225	COG0840	transmembrane signaling receptor activity
A361_25235	COG1012	belongs to the aldehyde dehydrogenase family
A361_25240	COG2610	gluconate transmembrane transporter activity
A361_25245	COG1454	alcohol dehydrogenase
A361_25250	COG3829	transcription factor binding
A361_25250	COG3290	protein histidine kinase activity
A361_25255	COG2610	gluconate transmembrane transporter activity
A361_25260	COG1609	Transcriptional regulator
A361_25275	COG1250	3-hydroxyacyl-CoA dehydrogenase
A361_25285	COG1363	Peptidase, m42
A361_25290	COG0747	negative chemotaxis
A361_25295	COG0402	S-adenosylhomocysteine deaminase activity
A361_25300	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A361_25320	COG1473	amidohydrolase
A361_25345	COG1609	Transcriptional regulator
A361_25360	COG0395	ABC-type sugar transport system, permease component
A361_25365	COG4209	transmembrane transport
A361_25370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A361_25405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A361_25410	COG1473	amidohydrolase
A361_25415	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A361_25420	COG1473	amidohydrolase
A361_25445	COG0737	Belongs to the 5'-nucleotidase family
A361_25455	COG3584	3D domain protein
A361_25455	COG1388	LysM domain
A361_25460	COG3409	Peptidoglycan-binding domain 1 protein
A361_25460	COG3773	Cell wall hydrolase
A361_25470	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A361_25475	COG3457	Alanine racemase
A361_25480	COG0626	cystathionine gamma-synthase activity
A361_25485	COG1735	metal-dependent hydrolase with the TIM-barrel fold
A361_25505	COG2188	Transcriptional regulator
A361_25515	COG3878	Protein conserved in bacteria
A361_25545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A361_25555	COG1725	Transcriptional regulator
A361_25605	COG0561	phosphatase activity
A361_25615	COG0629	single-stranded DNA binding
A361_25640	COG4786	Flagellar basal body rod
A361_25645	COG4786	Flagellar basal body rod
A361_25650	COG1077	Cell shape determining protein MreB Mrl
A361_25655	COG1609	Transcriptional regulator
A361_25665	COG0791	NLP P60 protein
A361_25665	COG1388	LysM domain
A361_25670	COG2176	DNA-directed DNA polymerase activity
A361_25680	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A361_25695	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A361_25700	COG0739	heme binding
A361_25710	COG2385	sporulation resulting in formation of a cellular spore
A361_25715	COG0583	DNA-binding transcription factor activity
A361_25720	COG1053	succinate dehydrogenase
A361_25740	COG3181	Tripartite tricarboxylate transporter family receptor
A361_25745	COG4565	transcriptional regulatory protein
A361_25750	COG3290	protein histidine kinase activity
A361_25765	COG4836	Membrane
A361_25770	COG1007	ATP synthesis coupled electron transport
A361_25775	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A361_25780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A361_25785	COG0713	ATP synthesis coupled electron transport
A361_25790	COG0839	Belongs to the complex I subunit 6 family
A361_25795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A361_25800	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A361_25810	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A361_25815	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A361_25820	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A361_25825	COG3584	3D domain protein
A361_25825	COG1388	LysM domain
A361_25840	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A361_25845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A361_25850	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A361_25855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A361_25865	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A361_25870	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A361_25875	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A361_25880	COG0356	it plays a direct role in the translocation of protons across the membrane
A361_25895	COG1404	Belongs to the peptidase S8 family
A361_25900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A361_25915	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A361_25935	COG1595	DNA-templated transcription, initiation
A361_25945	COG0698	ribose 5-phosphate isomerase
A361_25950	COG0840	transmembrane signaling receptor activity
A361_25960	COG1971	Probably functions as a manganese efflux pump
A361_25965	COG0009	L-threonylcarbamoyladenylate synthase
A361_25985	COG2890	protein-(glutamine-N5) methyltransferase activity
A361_25990	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A361_25995	COG1802	Transcriptional regulator
A361_26000	COG0697	spore germination
A361_26010	COG1435	thymidine kinase activity
A361_26020	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A361_26030	COG1494	fructose-1,6-bisphosphatase
A361_26035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A361_26040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A361_26045	COG0191	fructose-bisphosphate aldolase activity
A361_26050	COG2204	response regulator
A361_26055	COG4821	SIS domain
A361_26060	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A361_26065	COG1028	Short-chain dehydrogenase reductase Sdr
A361_26070	COG1312	Catalyzes the dehydration of D-mannonate
A361_26080	COG1063	alcohol dehydrogenase
A361_26085	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A361_26095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A361_26100	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A361_26105	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A361_26115	COG1609	Transcriptional regulator
A361_26120	COG0504	CTP synthase activity
A361_26135	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A361_26135	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A361_26135	COG1703	isobutyryl-CoA mutase activity
A361_26145	COG1960	acyl-CoA dehydrogenase activity
A361_26150	COG1960	acyl-CoA dehydrogenase activity
A361_26155	COG1250	3-hydroxyacyl-CoA dehydrogenase
A361_26160	COG0183	Belongs to the thiolase family
A361_26165	COG0247	lactate metabolic process
A361_26165	COG2181	nitrate reductase activity
A361_26170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A361_26175	COG4294	response to UV
A361_26180	COG5553	Cysteine dioxygenase type I
A361_26185	COG0697	spore germination
A361_26200	COG0018	arginyl-trna synthetase
A361_26205	COG4506	Protein conserved in bacteria
A361_26210	COG0010	Belongs to the arginase family
A361_26215	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A361_26220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A361_26230	COG1994	Peptidase M50
A361_26240	COG3465	dGTPase activity
A361_26245	COG1078	dGTPase activity
A361_26250	COG4844	belongs to the
A361_26260	COG0095	Lipoate-protein ligase
A361_26265	COG0280	phosphate acetyltransferase
A361_26285	COG2363	Small membrane protein
A361_26300	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A361_26315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A361_26320	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A361_26325	COG0314	molybdopterin synthase activity
A361_26330	COG0746	molybdenum cofactor guanylyltransferase activity
A361_26335	COG0351	phosphomethylpyrimidine kinase
A361_26340	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A361_26350	COG1874	Beta-galactosidase
A361_26350	COG0366	Alpha amylase catalytic
A361_26360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A361_26365	COG1131	(ABC) transporter
A361_26370	COG1511	domain protein
A361_26370	COG0842	Transport permease protein
A361_26385	COG0561	phosphatase activity
A361_26400	COG2031	fatty acid transporter
A361_26410	COG1131	(ABC) transporter
A361_26440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A361_26445	COG0366	Alpha amylase catalytic
A361_26455	COG0445	tRNA wobble uridine modification
A361_26470	COG2199	diguanylate cyclase activity
A361_26475	COG3104	oligopeptide transport
A361_26480	COG4297	protein containing double-stranded beta helix domain
A361_26485	COG2321	neutral zinc metallopeptidase
A361_26505	COG0477	Major facilitator Superfamily
A361_26520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A361_26525	COG1404	Belongs to the peptidase S8 family
A361_26530	COG0840	transmembrane signaling receptor activity
A361_26575	COG3708	Transcriptional regulator
A361_26575	COG2207	Transcriptional regulator
A361_26580	COG3620	sequence-specific DNA binding
A361_26585	COG0579	oxidoreductase
A361_26595	COG1621	beta-fructofuranosidase activity
A361_26630	COG1070	Carbohydrate kinase
A361_26640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A361_26645	COG1027	Aspartate ammonia-lyase
A361_26665	COG1172	Belongs to the binding-protein-dependent transport system permease family
A361_26670	COG1129	ABC transporter
A361_26675	COG1879	ABC-type sugar transport system periplasmic component
A361_26685	COG1082	Xylose isomerase domain protein TIM barrel
A361_26690	COG2169	Transcriptional regulator
A361_26705	COG5444	nuclease activity
A361_26710	COG1620	l-lactate permease
A361_26715	COG0039	L-malate dehydrogenase activity
A361_26730	COG0402	S-adenosylhomocysteine deaminase activity
A361_26735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A361_26740	COG2814	Major facilitator Superfamily
A361_26745	COG0772	Belongs to the SEDS family
A361_26750	COG1316	TRANSCRIPTIONal
A361_26755	COG1396	sequence-specific DNA binding
A361_26765	COG1113	amino acid transport
A361_26810	COG5444	nuclease activity
A361_26820	COG1279	arginine transmembrane transporter activity
A361_26850	COG2226	methyltransferase
A361_26940	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A361_26970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A361_26975	COG0494	nUDIX hydrolase
A361_26985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A361_26990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A361_26995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A361_27000	COG4853	Protein conserved in bacteria
A361_27005	COG4863	YycH protein
A361_27010	COG5002	protein histidine kinase activity
A361_27015	COG0745	RESPONSE REGULATOR receiver
A361_27050	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A361_27055	COG0305	Participates in initiation and elongation during chromosome replication
A361_27060	COG0359	binds to the 23S rRNA
A361_27065	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A361_27070	COG4241	membrane
A361_27075	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A361_27080	COG0629	single-stranded DNA binding
A361_27085	COG0360	Binds together with S18 to 16S ribosomal RNA
A361_27090	COG0012	GTP binding
A361_27100	COG0243	molybdopterin cofactor binding
A361_27105	COG4481	Protein conserved in bacteria
A361_27110	COG0668	transmembrane transport
A361_27125	COG1475	DNA binding
A361_27130	COG1192	Involved in chromosome partitioning
A361_27135	COG1475	DNA binding
A361_27140	COG0357	Ribosomal RNA small subunit methyltransferase G
A361_27145	COG0445	tRNA wobble uridine modification
A361_27150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A361_27155	COG1847	R3H domain protein
A361_27165	COG0594	ribonuclease P activity
A361_27170	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A361_27180	COG2385	sporulation resulting in formation of a cellular spore
A361_27230	COG0561	phosphatase activity
A361_27240	COG4974	Belongs to the 'phage' integrase family
A361_27255	COG2072	flavoprotein involved in K transport
A361_27260	COG0492	ferredoxin-NADP+ reductase activity
A361_27300	COG0640	Transcriptional regulator
A361_27305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A361_27310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A361_27335	COG0640	Transcriptional regulator
A361_27340	COG0346	lactoylglutathione lyase activity
A361_27350	COG2135	peptidase activity
A361_27375	COG4974	Belongs to the 'phage' integrase family
A361_27390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A361_27415	COG2072	flavoprotein involved in K transport
A361_27420	COG1686	Belongs to the peptidase S11 family
A361_27435	COG0745	RESPONSE REGULATOR receiver
A361_27445	COG4990	cell redox homeostasis
A361_27450	COG0745	RESPONSE REGULATOR receiver
A361_27455	COG5002	protein histidine kinase activity
A361_27465	COG0640	Transcriptional regulator
A361_27480	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A361_27485	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A361_27490	COG0366	Alpha amylase catalytic
A361_27495	COG3336	cytochrome c oxidase
A361_27515	COG1368	sulfuric ester hydrolase activity
A361_27520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A361_27525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A361_27530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A361_27535	COG1845	cytochrome c oxidase, subunit III
A361_27540	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A361_27555	COG0785	Cytochrome C biogenesis protein
A361_27560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A361_27575	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A361_27580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A361_27605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A361_27615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A361_27715	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A361_27725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A361_27730	COG0583	DNA-binding transcription factor activity
A361_27735	COG2986	histidine ammonia-lyase
A361_27745	COG4608	Belongs to the ABC transporter superfamily
A361_27750	COG0444	Belongs to the ABC transporter superfamily
A361_27755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A361_27760	COG0601	transmembrane transport
A361_27765	COG4166	transmembrane transport
A361_27770	COG5002	protein histidine kinase activity
A361_27775	COG0745	RESPONSE REGULATOR receiver
A361_27790	COG2226	methyltransferase
A361_27800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A361_27805	COG1333	cytochrome c biogenesis protein
A361_27810	COG0785	Cytochrome C biogenesis protein
A361_27815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A361_27825	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A361_27830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A361_27875	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A361_27880	COG4990	cell redox homeostasis
A361_27885	COG2124	cytochrome p450
A361_27905	COG1388	LysM domain
A361_27910	COG5002	protein histidine kinase activity
A361_27915	COG0745	RESPONSE REGULATOR receiver
A361_27935	COG2217	Heavy metal translocating P-type atpase
A361_27940	COG2608	mercury ion transmembrane transporter activity
A361_27960	COG0444	Belongs to the ABC transporter superfamily
A361_27965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A361_27970	COG0601	transmembrane transport
A361_27975	COG0747	negative chemotaxis
A361_27995	COG0860	N-Acetylmuramoyl-L-alanine amidase
A361_28005	COG2226	methyltransferase
A361_28010	COG1388	LysM domain
A361_28020	COG0803	Belongs to the bacterial solute-binding protein 9 family
A361_28025	COG1368	sulfuric ester hydrolase activity
A361_28030	COG4990	cell redox homeostasis
A361_28100	COG2132	Multicopper oxidase
A361_28105	COG0534	Mate efflux family protein
A361_28120	COG0745	RESPONSE REGULATOR receiver
A361_28135	COG0791	NLP P60 protein
A361_28135	COG3883	PFAM NLP P60 protein
A361_28180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A361_28185	COG0785	Cytochrome C biogenesis protein
A361_28195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_28210	COG0730	response to heat
A361_28215	COG0425	Belongs to the sulfur carrier protein TusA family
A361_28220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_28220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A361_28235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_28235	COG0425	Belongs to the sulfur carrier protein TusA family
A361_28250	COG2210	Belongs to the sulfur carrier protein TusA family
A361_28255	COG1937	Protein conserved in bacteria
A361_28285	COG0730	response to heat
A361_28290	COG0425	Belongs to the sulfur carrier protein TusA family
A361_28295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A361_28295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_28300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A361_28305	COG2210	Belongs to the sulfur carrier protein TusA family
A361_28310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_28310	COG0425	Belongs to the sulfur carrier protein TusA family
A361_28315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_28340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A361_28340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_28345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A361_28375	COG1793	dna ligase
A361_28400	COG0741	lytic transglycosylase activity
A361_28400	COG1196	nuclear chromosome segregation
A361_28400	COG0739	heme binding
A361_28470	COG2801	Transposase and inactivated derivatives
A361_28505	COG4712	double-strand break repair protein
A361_28510	COG0592	DNA-directed DNA polymerase activity
A361_28595	COG2199	diguanylate cyclase activity
A361_28595	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A361_28725	COG2003	Belongs to the UPF0758 family
A361_28795	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A361_28930	COG3157	Type VI secretion system effector, Hcp
A361_28955	COG4974	Belongs to the 'phage' integrase family
A361_29060	COG1288	antiporter activity
A361_29070	COG1473	amidohydrolase
A361_29075	COG4948	Mandelate Racemase Muconate Lactonizing
A361_29095	COG2814	Major facilitator Superfamily
A361_29115	COG2226	methyltransferase