locus-tag	class	description
BLMD_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BLMD_00010	COG0592	DNA-directed DNA polymerase activity
BLMD_00015	COG2501	S4 domain
BLMD_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BLMD_00030	COG0187	DNA topoisomerase II activity
BLMD_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLMD_00070	COG0517	IMP dehydrogenase activity
BLMD_00070	COG0516	GMP reductase activity
BLMD_00075	COG1686	Belongs to the peptidase S11 family
BLMD_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BLMD_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BLMD_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BLMD_00095	COG1929	Belongs to the glycerate kinase type-1 family
BLMD_00100	COG2610	gluconate transmembrane transporter activity
BLMD_00105	COG3835	regulator
BLMD_00120	COG1428	Deoxynucleoside kinase
BLMD_00125	COG1428	Deoxynucleoside kinase
BLMD_00130	COG3858	chitin binding
BLMD_00130	COG1388	LysM domain
BLMD_00135	COG1335	isochorismatase
BLMD_00140	COG0590	tRNA wobble adenosine to inosine editing
BLMD_00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BLMD_00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BLMD_00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BLMD_00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BLMD_00210	COG3853	Toxic anion resistance protein (TelA)
BLMD_00215	COG1982	Orn Lys Arg decarboxylase major
BLMD_00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BLMD_00225	COG3870	Protein conserved in bacteria
BLMD_00230	COG1728	Protein conserved in bacteria
BLMD_00235	COG0470	DNA polymerase III
BLMD_00240	COG1774	PSP1 C-terminal conserved region
BLMD_00245	COG4467	Involved in initiation control of chromosome replication
BLMD_00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BLMD_00255	COG2827	Endonuclease containing a URI domain
BLMD_00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BLMD_00265	COG2002	toxin-antitoxin pair type II binding
BLMD_00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLMD_00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLMD_00275	COG0084	hydrolase, TatD family'
BLMD_00280	COG3583	domain protein
BLMD_00280	COG3584	3D domain protein
BLMD_00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BLMD_00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BLMD_00300	COG4466	Protein conserved in bacteria
BLMD_00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BLMD_00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLMD_00320	COG0251	oxidation-reduction process
BLMD_00325	COG2088	sporulation resulting in formation of a cellular spore
BLMD_00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BLMD_00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BLMD_00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BLMD_00345	COG0193	aminoacyl-tRNA hydrolase activity
BLMD_00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BLMD_00360	COG2002	toxin-antitoxin pair type II binding
BLMD_00365	COG2244	polysaccharide biosynthetic process
BLMD_00370	COG3956	TIGRFAM MazG family protein
BLMD_00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BLMD_00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BLMD_00395	COG1098	S1 RNA binding domain
BLMD_00410	COG2208	phosphoserine phosphatase activity
BLMD_00415	COG2304	oxidoreductase activity
BLMD_00420	COG0515	serine threonine protein kinase
BLMD_00425	COG0037	tRNA processing
BLMD_00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BLMD_00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BLMD_00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BLMD_00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BLMD_00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLMD_00465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLMD_00470	COG0512	Glutamine amidotransferase of anthranilate synthase
BLMD_00475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLMD_00480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BLMD_00485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BLMD_00490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BLMD_00495	COG1396	sequence-specific DNA binding
BLMD_00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BLMD_00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BLMD_00585	COG4463	regulation of RNA biosynthetic process
BLMD_00590	COG3880	PFAM UvrB UvrC protein
BLMD_00595	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BLMD_00600	COG0542	response to heat
BLMD_00605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BLMD_00610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BLMD_00615	COG4956	integral membrane protein (PIN domain superfamily)
BLMD_00620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BLMD_00625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BLMD_00630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BLMD_00635	COG1045	serine acetyltransferase
BLMD_00640	COG0215	cysteine-tRNA ligase activity
BLMD_00645	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BLMD_00650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLMD_00655	COG3688	RNA-binding protein containing a PIN domain
BLMD_00675	COG0250	Participates in transcription elongation, termination and antitermination
BLMD_00680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BLMD_00685	COG0081	regulation of translation
BLMD_00690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BLMD_00695	COG0222	ribosome binding
BLMD_00700	COG2813	Specifically methylates the guanine in position
BLMD_00705	COG0085	RNA polymerase activity
BLMD_00710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BLMD_00715	COG1358	cellular component organization or biogenesis
BLMD_00720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BLMD_00725	COG0049	tRNA binding
BLMD_00730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BLMD_00735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BLMD_00740	COG0051	transcription antitermination factor activity, RNA binding
BLMD_00745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BLMD_00750	COG0088	Forms part of the polypeptide exit tunnel
BLMD_00755	COG0089	rRNA binding
BLMD_00765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BLMD_00770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BLMD_00775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BLMD_00780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BLMD_00785	COG0255	Belongs to the universal ribosomal protein uL29 family
BLMD_00790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BLMD_00795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BLMD_00800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BLMD_00805	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BLMD_00810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLMD_00815	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BLMD_00820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BLMD_00825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BLMD_00830	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BLMD_00835	COG1841	ribosomal large subunit assembly
BLMD_00840	COG0200	Binds to the 23S rRNA
BLMD_00845	COG0201	protein transport
BLMD_00850	COG0563	adenylate kinase activity
BLMD_00855	COG0024	Methionine aminopeptidase
BLMD_00860	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BLMD_00865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BLMD_00870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BLMD_00875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BLMD_00880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BLMD_00885	COG0202	RNA polymerase activity
BLMD_00890	COG0203	ribosomal protein L17
BLMD_00895	COG1122	ATPase activity
BLMD_00900	COG1122	ATPase activity
BLMD_00905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BLMD_00910	COG0101	tRNA pseudouridine synthase activity
BLMD_00915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BLMD_00920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BLMD_00945	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BLMD_00950	COG2318	DinB family
BLMD_00970	COG1131	(ABC) transporter
BLMD_01000	COG2274	protein secretion by the type I secretion system
BLMD_01025	COG3290	protein histidine kinase activity
BLMD_01050	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLMD_01055	COG0489	protein tyrosine kinase activity
BLMD_01065	COG2194	sulfuric ester hydrolase activity
BLMD_01070	COG0726	polysaccharide deacetylase
BLMD_01100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLMD_01110	COG0385	Bile acid
BLMD_01125	COG3876	Protein conserved in bacteria
BLMD_01130	COG1472	Belongs to the glycosyl hydrolase 3 family
BLMD_01135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLMD_01140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_01140	COG1263	PTS System
BLMD_01145	COG1737	Transcriptional regulator
BLMD_01150	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BLMD_01155	COG1683	Conserved Protein
BLMD_01190	COG1595	DNA-templated transcription, initiation
BLMD_01195	COG5662	AntiSigma factor
BLMD_01200	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BLMD_01205	COG4856	YbbR-like protein
BLMD_01210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLMD_01215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BLMD_01235	COG1725	Transcriptional regulator
BLMD_01240	COG0640	Transcriptional regulator
BLMD_01250	COG2814	Major facilitator Superfamily
BLMD_01255	COG1309	transcriptional regulator
BLMD_01270	COG1132	(ABC) transporter
BLMD_01275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BLMD_01285	COG1132	(ABC) transporter
BLMD_01290	COG2312	Erythromycin esterase
BLMD_01310	COG1011	Hydrolase
BLMD_01330	COG2211	Major facilitator Superfamily
BLMD_01350	COG1331	Highly conserved protein containing a thioredoxin domain
BLMD_01355	COG0697	spore germination
BLMD_01360	COG0789	Transcriptional regulator
BLMD_01385	COG2226	methyltransferase
BLMD_01390	COG0076	glutamate decarboxylase activity
BLMD_01395	COG0778	Nitroreductase
BLMD_01400	COG1802	Transcriptional regulator
BLMD_01405	COG0730	response to heat
BLMD_01425	COG1283	sodium-dependent phosphate transmembrane transporter activity
BLMD_01430	COG4682	membrane
BLMD_01455	COG0697	spore germination
BLMD_01460	COG1917	Cupin 2, conserved barrel domain protein
BLMD_01460	COG2207	Transcriptional regulator
BLMD_01470	COG2197	response regulator
BLMD_01485	COG0371	Dehydrogenase
BLMD_01500	COG4257	antibiotic catabolic process
BLMD_01510	COG0833	amino acid
BLMD_01515	COG2040	homocysteine
BLMD_01525	COG1263	PTS System
BLMD_01525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_01530	COG0789	Transcriptional regulator
BLMD_01535	COG2323	membrane
BLMD_01550	COG2205	protein histidine kinase activity
BLMD_01555	COG1115	amino acid carrier protein
BLMD_01560	COG2066	Belongs to the glutaminase family
BLMD_01565	COG4191	Histidine kinase
BLMD_01570	COG0784	Response regulator, receiver
BLMD_01595	COG3540	Alkaline phosphatase
BLMD_01600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BLMD_01605	COG0805	protein transport
BLMD_01610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLMD_01615	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_01620	COG2271	Major facilitator Superfamily
BLMD_01625	COG4948	Mandelate Racemase Muconate Lactonizing
BLMD_01630	COG2186	Transcriptional regulator
BLMD_01635	COG2721	sulfolactate sulfo-lyase activity
BLMD_01655	COG0745	RESPONSE REGULATOR receiver
BLMD_01660	COG2205	protein histidine kinase activity
BLMD_01665	COG1131	(ABC) transporter
BLMD_01690	COG3173	Aminoglycoside phosphotransferase
BLMD_01695	COG1846	Transcriptional regulator
BLMD_01700	COG0318	PFAM AMP-dependent synthetase and ligase
BLMD_01720	COG0789	Transcriptional regulator
BLMD_01745	COG0697	spore germination
BLMD_01755	COG1405	negative regulation of cell septum assembly
BLMD_01755	COG3012	SEC-C Motif Domain Protein
BLMD_01785	COG0583	DNA-binding transcription factor activity
BLMD_01790	COG1942	4-Oxalocrotonate Tautomerase
BLMD_01795	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_01810	COG1288	antiporter activity
BLMD_01820	COG0252	asparaginase activity
BLMD_01825	COG0456	acetyltransferase
BLMD_01835	COG1164	Oligoendopeptidase f
BLMD_01840	COG2261	transglycosylase associated protein
BLMD_01850	COG0247	lactate metabolic process
BLMD_01855	COG0277	FAD linked oxidase domain protein
BLMD_01860	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_01865	COG1447	Phosphotransferase system cellobiose-specific component IIA
BLMD_01870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_01875	COG1486	melibiose metabolic process
BLMD_01885	COG3394	polysaccharide catabolic process
BLMD_01900	COG3591	Belongs to the peptidase S1B family
BLMD_01905	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_01915	COG1595	DNA-templated transcription, initiation
BLMD_01925	COG3773	Cell wall hydrolase
BLMD_01930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLMD_01935	COG3883	PFAM NLP P60 protein
BLMD_01935	COG0791	NLP P60 protein
BLMD_01945	COG1131	(ABC) transporter
BLMD_01950	COG1309	transcriptional regulator
BLMD_01965	COG2310	stress, protein
BLMD_01970	COG2310	stress, protein
BLMD_01975	COG2310	stress, protein
BLMD_01980	COG0861	Integral membrane protein TerC family
BLMD_02000	COG3853	Toxic anion resistance protein (TelA)
BLMD_02005	COG0785	Cytochrome C biogenesis protein
BLMD_02015	COG0789	Transcriptional regulator
BLMD_02020	COG2223	nitrite transmembrane transporter activity
BLMD_02025	COG0039	L-malate dehydrogenase activity
BLMD_02030	COG1620	l-lactate permease
BLMD_02035	COG1280	lysine exporter protein (LysE YggA)
BLMD_02040	COG1113	amino acid transport
BLMD_02045	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BLMD_02050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BLMD_02055	COG3541	Predicted nucleotidyltransferase
BLMD_02065	COG0506	proline dehydrogenase activity
BLMD_02070	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_02075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLMD_02080	COG2508	Transcriptional regulator
BLMD_02085	COG3689	TIGRFAM TIGR03943 family protein
BLMD_02090	COG0701	Predicted permease
BLMD_02095	COG3458	cephalosporin-C deacetylase activity
BLMD_02100	COG1846	Transcriptional regulator
BLMD_02115	COG0765	amino acid transport
BLMD_02120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLMD_02125	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLMD_02135	COG2723	6-phospho-beta-galactosidase activity
BLMD_02145	COG3209	COG3209 Rhs family protein
BLMD_02155	COG0515	serine threonine protein kinase
BLMD_02160	COG3290	protein histidine kinase activity
BLMD_02160	COG0840	transmembrane signaling receptor activity
BLMD_02165	COG5444	nuclease activity
BLMD_02185	COG3842	ATPase activity
BLMD_02190	COG1176	ABC-type spermidine putrescine transport system, permease component I
BLMD_02195	COG1177	transmembrane transport
BLMD_02205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_02210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_02215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_02220	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BLMD_02225	COG0697	spore germination
BLMD_02230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_02240	COG2819	hydrolase of the alpha beta superfamily
BLMD_02245	COG3708	Transcriptional regulator
BLMD_02245	COG2207	Transcriptional regulator
BLMD_02250	COG2364	Membrane
BLMD_02280	COG1126	abc transporter atp-binding protein
BLMD_02285	COG0765	amino acid transport
BLMD_02290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLMD_02295	COG3829	transcription factor binding
BLMD_02300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BLMD_02305	COG0833	amino acid
BLMD_02310	COG0010	Belongs to the arginase family
BLMD_02315	COG0583	DNA-binding transcription factor activity
BLMD_02320	COG0163	prenyltransferase activity
BLMD_02325	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BLMD_02415	COG2972	Histidine kinase
BLMD_02420	COG4753	response regulator
BLMD_02420	COG2207	Transcriptional regulator
BLMD_02425	COG4213	ABC transporter substrate-binding protein
BLMD_02435	COG4214	carbohydrate transport
BLMD_02440	COG2271	Major facilitator Superfamily
BLMD_02445	COG1846	Transcriptional regulator
BLMD_02445	COG0456	acetyltransferase
BLMD_02450	COG1874	Beta-galactosidase
BLMD_02455	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BLMD_02465	COG3104	oligopeptide transport
BLMD_02470	COG5434	Belongs to the glycosyl hydrolase 28 family
BLMD_02480	COG0697	spore germination
BLMD_02490	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BLMD_02495	COG0789	Transcriptional regulator
BLMD_02500	COG1136	(ABC) transporter
BLMD_02505	COG0577	efflux transmembrane transporter activity
BLMD_02510	COG0745	RESPONSE REGULATOR receiver
BLMD_02515	COG3850	Histidine kinase
BLMD_02515	COG5002	protein histidine kinase activity
BLMD_02520	COG0840	transmembrane signaling receptor activity
BLMD_02525	COG0527	aspartate kinase activity
BLMD_02530	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_02535	COG4605	iron ion homeostasis
BLMD_02540	COG4604	ABC transporter, ATP-binding protein
BLMD_02545	COG4607	ABC-type enterochelin transport system periplasmic component
BLMD_02550	COG2814	Major facilitator Superfamily
BLMD_02555	COG1309	transcriptional regulator
BLMD_02565	COG0778	Nitroreductase
BLMD_02570	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BLMD_02575	COG0640	Transcriptional regulator
BLMD_02580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_02585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BLMD_02590	COG0531	amino acid
BLMD_02595	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_02600	COG0697	spore germination
BLMD_02610	COG4549	nuclear export factor GLE1
BLMD_02615	COG2372	response to copper ion
BLMD_02615	COG1276	copper resistance
BLMD_02620	COG1349	DNA-binding transcription factor activity
BLMD_02625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BLMD_02630	COG0243	molybdopterin cofactor binding
BLMD_02635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BLMD_02640	COG2146	nitrite reductase [NAD(P)H] activity
BLMD_02645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BLMD_02645	COG1587	Uroporphyrinogen-III synthase
BLMD_02650	COG1802	Transcriptional regulator
BLMD_02655	COG0471	metal ion transport
BLMD_02660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BLMD_02670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_02685	COG3959	Transketolase, thiamine diphosphate binding domain
BLMD_02690	COG3958	Transketolase
BLMD_02695	COG0561	phosphatase activity
BLMD_02700	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BLMD_02705	COG1914	H( )-stimulated, divalent metal cation uptake system
BLMD_02710	COG4336	lyase activity
BLMD_02715	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BLMD_02720	COG1984	allophanate hydrolase subunit 2
BLMD_02725	COG1414	Transcriptional regulator
BLMD_02730	COG2755	lipolytic protein G-D-S-L family
BLMD_02735	COG2213	PTS system mannitol-specific
BLMD_02740	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_02745	COG0246	Mannitol dehydrogenase
BLMD_02750	COG3711	transcriptional antiterminator
BLMD_02755	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_02760	COG1917	Cupin 2, conserved barrel domain protein
BLMD_02770	COG3871	stress protein (general stress protein 26)
BLMD_02780	COG1316	TRANSCRIPTIONal
BLMD_02785	COG2814	Major facilitator Superfamily
BLMD_02795	COG1522	sequence-specific DNA binding
BLMD_02800	COG0551	DNA topoisomerase type I activity
BLMD_02800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLMD_02805	COG0287	Prephenate dehydrogenase
BLMD_02810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLMD_02810	COG0512	Glutamine amidotransferase of anthranilate synthase
BLMD_02815	COG1605	Chorismate mutase
BLMD_02820	COG0028	Belongs to the TPP enzyme family
BLMD_02825	COG3397	chitin binding
BLMD_02835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLMD_02840	COG1914	H( )-stimulated, divalent metal cation uptake system
BLMD_02845	COG2261	transglycosylase associated protein
BLMD_02850	COG1027	Aspartate ammonia-lyase
BLMD_02855	COG1819	glycosyl
BLMD_02860	COG4876	unkown
BLMD_02865	COG2217	Heavy metal translocating P-type atpase
BLMD_02875	COG0662	Cupin 2, conserved barrel domain protein
BLMD_02885	COG0628	permease
BLMD_02890	COG1301	dicarboxylic acid transport
BLMD_02895	COG1131	(ABC) transporter
BLMD_02900	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BLMD_02910	COG1960	acyl-CoA dehydrogenase activity
BLMD_02925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_02930	COG1181	Belongs to the D-alanine--D-alanine ligase family
BLMD_02935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BLMD_02945	COG0513	Belongs to the DEAD box helicase family
BLMD_02950	COG3402	PFAM membrane-flanked domain
BLMD_02955	COG3428	Bacterial PH domain
BLMD_02960	COG0705	Rhomboid family
BLMD_02965	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BLMD_02970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BLMD_02975	COG0864	Transcriptional regulator
BLMD_02980	COG2337	Toxic component of a toxin-antitoxin (TA) module
BLMD_02985	COG1366	Belongs to the anti-sigma-factor antagonist family
BLMD_02990	COG1366	Belongs to the anti-sigma-factor antagonist family
BLMD_02995	COG2172	sigma factor antagonist activity
BLMD_03000	COG2208	phosphoserine phosphatase activity
BLMD_03015	COG1191	sigma factor activity
BLMD_03020	COG2208	phosphoserine phosphatase activity
BLMD_03025	COG2183	response to ionizing radiation
BLMD_03030	COG1309	transcriptional regulator
BLMD_03040	COG2409	Drug exporters of the RND superfamily
BLMD_03040	COG1033	growth of symbiont in host cell
BLMD_03045	COG3091	SprT-like family
BLMD_03110	COG0726	polysaccharide deacetylase
BLMD_03115	COG3239	Fatty acid desaturase
BLMD_03120	COG1278	Cold shock
BLMD_03125	COG1329	Transcriptional regulator
BLMD_03135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_03140	COG0477	Major facilitator Superfamily
BLMD_03150	COG2364	Membrane
BLMD_03155	COG1846	Transcriptional regulator
BLMD_03160	COG0456	acetyltransferase
BLMD_03165	COG2808	Putative FMN-binding domain
BLMD_03175	COG1733	regulation of RNA biosynthetic process
BLMD_03180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_03195	COG3545	Serine hydrolase
BLMD_03200	COG1733	regulation of RNA biosynthetic process
BLMD_03215	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BLMD_03220	COG1113	amino acid transport
BLMD_03235	COG0596	Alpha beta hydrolase
BLMD_03240	COG5566	PFAM Mor transcription activator
BLMD_03245	COG1595	DNA-templated transcription, initiation
BLMD_03255	COG2755	lipolytic protein G-D-S-L family
BLMD_03255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BLMD_03260	COG0494	nUDIX hydrolase
BLMD_03265	COG2814	Major facilitator Superfamily
BLMD_03270	COG1979	alcohol dehydrogenase
BLMD_03275	COG0745	RESPONSE REGULATOR receiver
BLMD_03275	COG2972	Histidine kinase
BLMD_03280	COG3279	Response regulator of the LytR AlgR family
BLMD_03290	COG3764	Sortase (surface protein transpeptidase)
BLMD_03300	COG2814	Major facilitator Superfamily
BLMD_03340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BLMD_03345	COG0802	atpase or kinase
BLMD_03350	COG1214	PFAM Peptidase M22, glycoprotease
BLMD_03355	COG0456	acetyltransferase
BLMD_03360	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BLMD_03365	COG0488	(ABC) transporter
BLMD_03370	COG0315	cyclic pyranopterin monophosphate synthase activity
BLMD_03375	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BLMD_03380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BLMD_03385	COG0805	protein transport
BLMD_03395	COG1266	CAAX protease self-immunity
BLMD_03400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BLMD_03405	COG0459	protein refolding
BLMD_03420	COG2720	vancomycin resistance protein
BLMD_03440	COG2135	peptidase activity
BLMD_03450	COG1309	transcriptional regulator
BLMD_03455	COG3848	Pyruvate phosphate dikinase
BLMD_03455	COG0574	Belongs to the PEP-utilizing enzyme family
BLMD_03465	COG3189	MarR family transcriptional regulator
BLMD_03470	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BLMD_03475	COG2272	Belongs to the type-B carboxylesterase lipase family
BLMD_03480	COG2814	Major facilitator Superfamily
BLMD_03485	COG1842	Phage shock protein A
BLMD_03490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BLMD_03495	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BLMD_03500	COG4260	virion core protein, lumpy skin disease virus
BLMD_03510	COG1378	Sugar-specific transcriptional regulator TrmB
BLMD_03515	COG1280	lysine exporter protein (LysE YggA)
BLMD_03520	COG3339	Conserved Protein
BLMD_03525	COG0772	Belongs to the SEDS family
BLMD_03530	COG0772	Belongs to the SEDS family
BLMD_03550	COG0726	polysaccharide deacetylase
BLMD_03560	COG1609	Transcriptional regulator
BLMD_03565	COG0366	Alpha amylase catalytic
BLMD_03570	COG2182	Extracellular solute-binding protein
BLMD_03575	COG1175	transmembrane transport
BLMD_03580	COG3833	ABC-type maltose transport systems, permease component
BLMD_03585	COG5521	maltodextrose utilization protein MalA
BLMD_03590	COG1554	hydrolase, family 65, central catalytic
BLMD_03595	COG0366	Alpha amylase catalytic
BLMD_03600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BLMD_03605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BLMD_03610	COG1846	Transcriptional regulator
BLMD_03625	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BLMD_03630	COG0823	Involved in the tonB-independent uptake of proteins
BLMD_03660	COG0702	epimerase
BLMD_03670	COG2132	Multicopper oxidase
BLMD_03690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BLMD_03695	COG0714	Associated with various cellular activities
BLMD_03700	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BLMD_03705	COG1305	Transglutaminase-like
BLMD_03710	COG0519	Catalyzes the synthesis of GMP from XMP
BLMD_03710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BLMD_03720	COG2252	PERMEase
BLMD_03735	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BLMD_03745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BLMD_03750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BLMD_03755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BLMD_03760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BLMD_03765	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLMD_03770	COG0047	phosphoribosylformylglycinamidine synthase activity
BLMD_03775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLMD_03780	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BLMD_03785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BLMD_03790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BLMD_03795	COG0138	bifunctional purine biosynthesis protein purh
BLMD_03800	COG0151	Belongs to the GarS family
BLMD_03810	COG2124	cytochrome p450
BLMD_03830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BLMD_03835	COG1470	cell adhesion involved in biofilm formation
BLMD_03840	COG4496	protein, YerC YecD
BLMD_03845	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BLMD_03850	COG0210	DNA helicase
BLMD_03855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BLMD_03860	COG4851	CamS sex pheromone cAM373 precursor
BLMD_03865	COG2188	Transcriptional regulator
BLMD_03885	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BLMD_03890	COG0626	cystathionine gamma-synthase activity
BLMD_03895	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BLMD_03900	COG3457	Alanine racemase
BLMD_03905	COG0363	glucosamine-6-phosphate deaminase activity
BLMD_03910	COG1285	pathogenesis
BLMD_03915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLMD_03920	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BLMD_03925	COG0154	amidase activity
BLMD_03930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BLMD_03945	COG4124	Belongs to the glycosyl hydrolase 26 family
BLMD_03950	COG1309	transcriptional regulator
BLMD_03955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BLMD_03965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLMD_03970	COG1957	nucleoside hydrolase
BLMD_03975	COG1597	lipid kinase activity
BLMD_03980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLMD_04015	COG3711	transcriptional antiterminator
BLMD_04020	COG0457	Tetratricopeptide repeat
BLMD_04035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLMD_04035	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BLMD_04040	COG3586	endonuclease activity
BLMD_04045	COG0697	spore germination
BLMD_04050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_04055	COG0697	spore germination
BLMD_04060	COG0217	transcriptional regulatory protein
BLMD_04090	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_04095	COG0840	transmembrane signaling receptor activity
BLMD_04100	COG0109	protoheme IX farnesyltransferase activity
BLMD_04105	COG1309	transcriptional regulator
BLMD_04110	COG0471	metal ion transport
BLMD_04115	COG0488	(ABC) transporter
BLMD_04120	COG0583	DNA-binding transcription factor activity
BLMD_04130	COG0640	Transcriptional regulator
BLMD_04135	COG1469	GTP cyclohydrolase I activity
BLMD_04150	COG0523	cobalamin synthesis protein
BLMD_04160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BLMD_04165	COG0156	8-amino-7-oxononanoate synthase activity
BLMD_04170	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BLMD_04175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BLMD_04180	COG2124	cytochrome p450
BLMD_04190	COG0789	Transcriptional regulator
BLMD_04195	COG2814	Major facilitator Superfamily
BLMD_04205	COG0488	(ABC) transporter
BLMD_04210	COG0513	Belongs to the DEAD box helicase family
BLMD_04215	COG2130	NADP-dependent
BLMD_04230	COG0471	metal ion transport
BLMD_04260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_04270	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BLMD_04275	COG3858	chitin binding
BLMD_04280	COG5658	integral membrane protein
BLMD_04285	COG0640	Transcriptional regulator
BLMD_04290	COG1254	Belongs to the acylphosphatase family
BLMD_04295	COG2258	MOSC domain
BLMD_04305	COG0024	Methionine aminopeptidase
BLMD_04310	COG1368	sulfuric ester hydrolase activity
BLMD_04320	COG1115	amino acid carrier protein
BLMD_04325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_04325	COG1263	PTS System
BLMD_04330	COG0366	Alpha amylase catalytic
BLMD_04335	COG2188	Transcriptional regulator
BLMD_04360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BLMD_04365	COG1045	serine acetyltransferase
BLMD_04370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLMD_04380	COG1215	transferase activity, transferring glycosyl groups
BLMD_04385	COG0457	Tetratricopeptide repeat
BLMD_04385	COG0463	Glycosyl transferase, family 2
BLMD_04395	COG0673	inositol 2-dehydrogenase activity
BLMD_04410	COG1733	regulation of RNA biosynthetic process
BLMD_04415	COG0778	Nitroreductase
BLMD_04420	COG0737	Belongs to the 5'-nucleotidase family
BLMD_04425	COG0693	protein deglycase activity
BLMD_04430	COG4840	Belongs to the UPF0435 family
BLMD_04435	COG1115	amino acid carrier protein
BLMD_04440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLMD_04445	COG4980	gas vesicle protein
BLMD_04450	COG1295	ribonuclease BN
BLMD_04455	COG0477	Major facilitator Superfamily
BLMD_04465	COG0387	Pfam Sodium calcium exchanger
BLMD_04475	COG0535	radical SAM domain protein
BLMD_04485	COG0726	polysaccharide deacetylase
BLMD_04490	COG0371	Dehydrogenase
BLMD_04500	COG0598	Magnesium transport protein CorA
BLMD_04505	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BLMD_04510	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLMD_04515	COG4637	Psort location Cytoplasmic, score
BLMD_04540	COG1819	glycosyl
BLMD_04550	COG0477	Major facilitator Superfamily
BLMD_04560	COG1263	PTS System
BLMD_04560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_04565	COG3711	transcriptional antiterminator
BLMD_04570	COG0288	reversible hydration of carbon dioxide
BLMD_04575	COG3002	Belongs to the UPF0753 family
BLMD_04580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BLMD_04585	COG5609	conserved protein (DUF2294)
BLMD_04595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BLMD_04600	COG0022	dehydrogenase e1 component
BLMD_04605	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLMD_04610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLMD_04615	COG3284	Transcriptional regulator
BLMD_04620	COG1742	UPF0060 membrane protein
BLMD_04625	COG1486	melibiose metabolic process
BLMD_04630	COG1737	Transcriptional regulator
BLMD_04635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_04635	COG1263	PTS System
BLMD_04650	COG1733	regulation of RNA biosynthetic process
BLMD_04655	COG2259	Doxx family
BLMD_04660	COG2514	catechol 2,3-dioxygenase activity
BLMD_04670	COG3507	Belongs to the glycosyl hydrolase 43 family
BLMD_04680	COG1653	transport
BLMD_04690	COG1051	belongs to the nudix hydrolase family
BLMD_04700	COG0392	lysyltransferase activity
BLMD_04700	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BLMD_04705	COG0384	phenazine biosynthesis protein PhzF
BLMD_04710	COG0778	Nitroreductase
BLMD_04730	COG1090	epimerase
BLMD_04735	COG2137	regulation of response to DNA damage stimulus
BLMD_04760	COG0463	Glycosyl transferase, family 2
BLMD_04770	COG4485	Bacterial membrane protein, YfhO
BLMD_04775	COG1988	membrane-bound metal-dependent
BLMD_04780	COG1194	a g-specific adenine glycosylase
BLMD_04790	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_04805	COG3557	Belongs to the UPF0374 family
BLMD_04810	COG1132	(ABC) transporter
BLMD_04815	COG0444	Belongs to the ABC transporter superfamily
BLMD_04820	COG4608	Belongs to the ABC transporter superfamily
BLMD_04825	COG0747	negative chemotaxis
BLMD_04840	COG4129	membrane
BLMD_04845	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BLMD_04850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BLMD_04855	COG0735	belongs to the Fur family
BLMD_04965	COG0457	Tetratricopeptide repeat
BLMD_05010	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BLMD_05030	COG0710	3-dehydroquinate dehydratase activity
BLMD_05035	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BLMD_05040	COG1116	anion transmembrane transporter activity
BLMD_05045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BLMD_05050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLMD_05055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLMD_05065	COG1476	TRANSCRIPTIONal
BLMD_05075	COG1131	(ABC) transporter
BLMD_05095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLMD_05105	COG3382	B3 4 domain protein
BLMD_05110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BLMD_05120	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BLMD_05125	COG0789	Transcriptional regulator
BLMD_05130	COG1664	Polymer-forming cytoskeletal
BLMD_05135	COG1664	Polymer-forming cytoskeletal
BLMD_05140	COG2766	serine protein kinase
BLMD_05145	COG2718	Belongs to the UPF0229 family
BLMD_05150	COG1566	PFAM secretion protein HlyD family protein
BLMD_05155	COG2814	Major facilitator Superfamily
BLMD_05160	COG0655	NAD(P)H dehydrogenase (quinone) activity
BLMD_05170	COG1131	(ABC) transporter
BLMD_05175	COG1131	(ABC) transporter
BLMD_05180	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BLMD_05185	COG1278	Cold shock
BLMD_05190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BLMD_05195	COG2011	ABC-type metal ion transport system permease component
BLMD_05200	COG1464	Belongs to the NlpA lipoprotein family
BLMD_05205	COG1823	symporter activity
BLMD_05230	COG5577	PFAM Coat F domain
BLMD_05240	COG5002	protein histidine kinase activity
BLMD_05245	COG4085	toxin activity
BLMD_05245	COG1525	nuclease
BLMD_05245	COG0737	Belongs to the 5'-nucleotidase family
BLMD_05250	COG3764	Sortase (surface protein transpeptidase)
BLMD_05255	COG0564	pseudouridine synthase activity
BLMD_05265	COG0517	IMP dehydrogenase activity
BLMD_05270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BLMD_05275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BLMD_05275	COG3153	acetyltransferase
BLMD_05280	COG0488	(ABC) transporter
BLMD_05285	COG2116	formate transmembrane transporter activity
BLMD_05300	COG0604	alcohol dehydrogenase
BLMD_05305	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BLMD_05310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BLMD_05315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BLMD_05320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BLMD_05325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLMD_05340	COG4585	Histidine kinase
BLMD_05340	COG2203	Gaf domain
BLMD_05345	COG2197	response regulator
BLMD_05350	COG0431	NADPH-dependent FMN reductase
BLMD_05365	COG1959	2 iron, 2 sulfur cluster binding
BLMD_05370	COG1017	nitric oxide dioxygenase activity
BLMD_05370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BLMD_05375	COG2719	SpoVR family
BLMD_05380	COG1388	LysM domain
BLMD_05380	COG0791	NLP P60 protein
BLMD_05385	COG0583	DNA-binding transcription factor activity
BLMD_05390	COG0372	Belongs to the citrate synthase family
BLMD_05400	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_05405	COG0733	neurotransmitter:sodium symporter activity
BLMD_05435	COG2207	Transcriptional regulator
BLMD_05435	COG3708	Transcriptional regulator
BLMD_05440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_05460	COG1595	DNA-templated transcription, initiation
BLMD_05465	COG0662	Cupin 2, conserved barrel domain protein
BLMD_05470	COG0667	Aldo Keto reductase
BLMD_05475	COG0204	Acyl-transferase
BLMD_05480	COG3152	Membrane
BLMD_05495	COG1253	flavin adenine dinucleotide binding
BLMD_05500	COG0789	Transcriptional regulator
BLMD_05505	COG1253	flavin adenine dinucleotide binding
BLMD_05525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLMD_05530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLMD_05535	COG0584	glycerophosphoryl diester phosphodiesterase
BLMD_05540	COG0668	transmembrane transport
BLMD_05545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BLMD_05555	COG0726	polysaccharide deacetylase
BLMD_05565	COG1757	Na H antiporter
BLMD_05570	COG2017	converts alpha-aldose to the beta-anomer
BLMD_05605	COG0589	response to stress
BLMD_05610	COG1132	(ABC) transporter
BLMD_05615	COG1132	(ABC) transporter
BLMD_05620	COG0702	epimerase
BLMD_05635	COG3842	ATPase activity
BLMD_05640	COG2508	Transcriptional regulator
BLMD_05650	COG0189	ligase activity
BLMD_05655	COG0189	ligase activity
BLMD_05660	COG4399	Belongs to the UPF0754 family
BLMD_05665	COG3679	Belongs to the UPF0342 family
BLMD_05675	COG0561	phosphatase activity
BLMD_05680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BLMD_05685	COG0475	glutathione-regulated potassium exporter activity
BLMD_05690	COG0490	domain, Protein
BLMD_05700	COG1024	Enoyl-CoA hydratase
BLMD_05705	COG0457	Tetratricopeptide repeat
BLMD_05720	COG4152	abc transporter atp-binding protein
BLMD_05725	COG1668	transmembrane transport
BLMD_05730	COG0420	3'-5' exonuclease activity
BLMD_05735	COG4717	serine-type aminopeptidase activity
BLMD_05740	COG3481	metal-dependent phosphohydrolase, HD sub domain
BLMD_05750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BLMD_05780	COG1846	Transcriptional regulator
BLMD_05785	COG4980	gas vesicle protein
BLMD_05800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BLMD_05805	COG0537	adenosine 5'-monophosphoramidase activity
BLMD_05815	COG1131	(ABC) transporter
BLMD_05820	COG4473	ABC transporter
BLMD_05830	COG1473	amidohydrolase
BLMD_05835	COG3069	C4-dicarboxylate transmembrane transporter activity
BLMD_05840	COG2329	Antibiotic biosynthesis monooxygenase
BLMD_05845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLMD_05850	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BLMD_05865	COG1309	transcriptional regulator
BLMD_05870	COG1511	domain protein
BLMD_05875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLMD_05880	COG1363	Peptidase, m42
BLMD_05890	COG1301	dicarboxylic acid transport
BLMD_05900	COG1234	tRNA 3'-trailer cleavage
BLMD_05905	COG0095	Lipoate-protein ligase
BLMD_05910	COG0318	PFAM AMP-dependent synthetase and ligase
BLMD_05920	COG1396	sequence-specific DNA binding
BLMD_05935	COG0501	Belongs to the peptidase M48B family
BLMD_05945	COG0697	spore germination
BLMD_05950	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BLMD_05960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_05965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_05970	COG0406	alpha-ribazole phosphatase activity
BLMD_05975	COG0840	transmembrane signaling receptor activity
BLMD_05980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BLMD_05980	COG0723	plastoquinol--plastocyanin reductase activity
BLMD_05985	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_05995	COG4903	ComK protein
BLMD_06005	COG0398	Pfam SNARE associated Golgi protein
BLMD_06010	COG0681	Belongs to the peptidase S26 family
BLMD_06020	COG1404	Belongs to the peptidase S8 family
BLMD_06030	COG2508	Transcriptional regulator
BLMD_06035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BLMD_06040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLMD_06045	COG3257	ureidoglycine aminohydrolase activity
BLMD_06050	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BLMD_06055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BLMD_06060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BLMD_06065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BLMD_06075	COG0549	Belongs to the carbamate kinase family
BLMD_06080	COG2814	Major facilitator Superfamily
BLMD_06090	COG0457	Tetratricopeptide repeat
BLMD_06125	COG1486	melibiose metabolic process
BLMD_06130	COG3180	Ammonia monooxygenase
BLMD_06145	COG3546	catalase activity
BLMD_06150	COG0318	PFAM AMP-dependent synthetase and ligase
BLMD_06155	COG0477	Major facilitator Superfamily
BLMD_06155	COG2814	Major facilitator Superfamily
BLMD_06160	COG4533	DNA binding
BLMD_06170	COG5002	protein histidine kinase activity
BLMD_06175	COG0745	RESPONSE REGULATOR receiver
BLMD_06180	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BLMD_06185	COG0725	ABC transporter, periplasmic molybdate-binding protein
BLMD_06190	COG4149	molybdate abc transporter
BLMD_06195	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BLMD_06200	COG1074	ATP-dependent DNA helicase activity
BLMD_06205	COG0420	3'-5' exonuclease activity
BLMD_06210	COG0419	ATPase involved in DNA repair
BLMD_06255	COG5337	Spore coat protein CotH
BLMD_06265	COG0179	Fumarylacetoacetate (FAA) hydrolase
BLMD_06290	COG0367	asparagine synthase
BLMD_06295	COG0004	ammonium transporteR
BLMD_06300	COG0347	Belongs to the P(II) protein family
BLMD_06305	COG0534	Mate efflux family protein
BLMD_06310	COG1917	Cupin 2, conserved barrel domain protein
BLMD_06310	COG2207	Transcriptional regulator
BLMD_06320	COG1609	Transcriptional regulator
BLMD_06325	COG0673	inositol 2-dehydrogenase activity
BLMD_06340	COG0697	spore germination
BLMD_06345	COG1279	arginine transmembrane transporter activity
BLMD_06350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_06360	COG0076	glutamate decarboxylase activity
BLMD_06385	COG2153	protein acetylation
BLMD_06390	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_06395	COG2378	regulation of single-species biofilm formation
BLMD_06400	COG1410	methionine synthase
BLMD_06400	COG0646	methionine synthase
BLMD_06405	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BLMD_06405	COG0646	methionine synthase
BLMD_06410	COG1666	GTP binding
BLMD_06415	COG2996	Protein conserved in bacteria
BLMD_06425	COG1307	EDD domain protein, DegV family
BLMD_06430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_06440	COG0516	GMP reductase activity
BLMD_06450	COG0561	phosphatase activity
BLMD_06455	COG1073	alpha beta
BLMD_06460	COG2151	metal-sulfur cluster biosynthetic enzyme
BLMD_06470	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BLMD_06475	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BLMD_06480	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BLMD_06485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BLMD_06490	COG0505	Belongs to the CarA family
BLMD_06495	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BLMD_06500	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BLMD_06505	COG1968	undecaprenyl-diphosphatase activity
BLMD_06520	COG2267	carboxylic ester hydrolase activity
BLMD_06530	COG1744	ABC transporter substrate-binding protein PnrA-like
BLMD_06545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLMD_06550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BLMD_06555	COG5504	Zn-dependent protease
BLMD_06560	COG0444	Belongs to the ABC transporter superfamily
BLMD_06565	COG4608	Belongs to the ABC transporter superfamily
BLMD_06575	COG0601	transmembrane transport
BLMD_06580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLMD_06595	COG0180	Tryptophanyl-tRNA synthetase
BLMD_06605	COG4166	transmembrane transport
BLMD_06610	COG0601	transmembrane transport
BLMD_06615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLMD_06620	COG0444	Belongs to the ABC transporter superfamily
BLMD_06625	COG4608	Belongs to the ABC transporter superfamily
BLMD_06630	COG0456	acetyltransferase
BLMD_06635	COG1393	Belongs to the ArsC family
BLMD_06640	COG0861	Integral membrane protein TerC family
BLMD_06645	COG4862	establishment of competence for transformation
BLMD_06670	COG4565	transcriptional regulatory protein
BLMD_06675	COG3290	protein histidine kinase activity
BLMD_06680	COG4469	Competence protein
BLMD_06685	COG1164	Oligoendopeptidase f
BLMD_06700	COG2346	COG2346, Truncated hemoglobins
BLMD_06710	COG0741	lytic transglycosylase activity
BLMD_06715	COG4116	CYTH
BLMD_06725	COG2357	RelA SpoT domain protein
BLMD_06730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BLMD_06735	COG0564	pseudouridine synthase activity
BLMD_06740	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BLMD_06750	COG0475	glutathione-regulated potassium exporter activity
BLMD_06750	COG0569	domain protein
BLMD_06755	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BLMD_06760	COG0352	thiamine-phosphate diphosphorylase activity
BLMD_06770	COG2104	thiamine diphosphate biosynthetic process
BLMD_06775	COG2022	thiamine diphosphate biosynthetic process
BLMD_06780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BLMD_06785	COG0351	phosphomethylpyrimidine kinase
BLMD_06790	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BLMD_06845	COG0210	DNA helicase
BLMD_06855	COG0586	Pfam SNARE associated Golgi protein
BLMD_06860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLMD_06865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BLMD_06870	COG2246	polysaccharide biosynthetic process
BLMD_06875	COG2153	protein acetylation
BLMD_06880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BLMD_06885	COG2382	esterase
BLMD_06905	COG0626	cystathionine gamma-synthase activity
BLMD_06910	COG0626	cystathionine gamma-synthase activity
BLMD_06915	COG5505	Protein of unknown function (DUF819)
BLMD_06930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLMD_06940	COG3507	Belongs to the glycosyl hydrolase 43 family
BLMD_07015	COG0110	maltose O-acetyltransferase activity
BLMD_07025	COG0583	DNA-binding transcription factor activity
BLMD_07030	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BLMD_07035	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BLMD_07040	COG0583	DNA-binding transcription factor activity
BLMD_07050	COG0346	lactoylglutathione lyase activity
BLMD_07060	COG3584	3D domain protein
BLMD_07060	COG1388	LysM domain
BLMD_07065	COG2814	Major facilitator Superfamily
BLMD_07070	COG1309	transcriptional regulator
BLMD_07090	COG5444	nuclease activity
BLMD_07095	COG4195	phage-related replication protein
BLMD_07100	COG2856	Zn peptidase
BLMD_07105	COG1396	sequence-specific DNA binding
BLMD_07120	COG1522	sequence-specific DNA binding
BLMD_07125	COG1484	DNA-dependent DNA replication
BLMD_07140	COG1595	DNA-templated transcription, initiation
BLMD_07145	COG5484	DNA packaging
BLMD_07145	COG3728	DNA packaging
BLMD_07150	COG1783	phage Terminase large subunit
BLMD_07155	COG5518	Phage portal protein
BLMD_07160	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BLMD_07165	COG4653	Phage capsid family
BLMD_07210	COG3953	SLT domain
BLMD_07210	COG5280	Phage tail tape measure protein TP901
BLMD_07215	COG1652	LysM domain
BLMD_07220	COG4193	domain, Protein
BLMD_07230	COG3628	GPW Gp25 family protein
BLMD_07235	COG3299	homolog of phage Mu protein gp47
BLMD_07240	COG3778	Protein conserved in bacteria
BLMD_07265	COG3594	Acyltransferase
BLMD_07275	COG1802	Transcriptional regulator
BLMD_07280	COG1063	alcohol dehydrogenase
BLMD_07285	COG1312	Catalyzes the dehydration of D-mannonate
BLMD_07290	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_07295	COG1063	alcohol dehydrogenase
BLMD_07300	COG2271	Major facilitator Superfamily
BLMD_07315	COG0306	phosphate transporter
BLMD_07320	COG1392	Phosphate transport regulator
BLMD_07325	COG0405	Gamma-glutamyltransferase
BLMD_07330	COG5578	integral membrane protein
BLMD_07335	COG2972	Histidine kinase
BLMD_07340	COG4753	response regulator
BLMD_07340	COG2207	Transcriptional regulator
BLMD_07345	COG1653	transport
BLMD_07350	COG1175	transmembrane transport
BLMD_07355	COG0395	ABC-type sugar transport system, permease component
BLMD_07360	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BLMD_07365	COG2207	Transcriptional regulator
BLMD_07370	COG2755	lipolytic protein G-D-S-L family
BLMD_07380	COG5578	integral membrane protein
BLMD_07385	COG3401	FG-GAP repeat protein
BLMD_07395	COG2755	lipolytic protein G-D-S-L family
BLMD_07400	COG3401	FG-GAP repeat protein
BLMD_07405	COG0667	Aldo Keto reductase
BLMD_07410	COG1874	Beta-galactosidase
BLMD_07420	COG1653	transport
BLMD_07425	COG4209	transmembrane transport
BLMD_07430	COG0395	ABC-type sugar transport system, permease component
BLMD_07435	COG0531	amino acid
BLMD_07440	COG0346	lactoylglutathione lyase activity
BLMD_07445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLMD_07450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLMD_07460	COG2362	D-Aminopeptidase
BLMD_07465	COG0601	transmembrane transport
BLMD_07470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLMD_07475	COG0444	Belongs to the ABC transporter superfamily
BLMD_07480	COG4166	transmembrane transport
BLMD_07485	COG1619	proteins homologs of microcin C7 resistance protein MccF
BLMD_07490	COG4948	Mandelate Racemase Muconate Lactonizing
BLMD_07495	COG0791	NLP P60 protein
BLMD_07500	COG4608	Belongs to the ABC transporter superfamily
BLMD_07510	COG1834	amidinotransferase
BLMD_07515	COG1607	acyl-coa hydrolase
BLMD_07520	COG2323	membrane
BLMD_07525	COG3866	Pectate lyase
BLMD_07545	COG2318	DinB family
BLMD_07550	COG2076	Multidrug Resistance protein
BLMD_07555	COG2076	Multidrug Resistance protein
BLMD_07560	COG0788	formyltetrahydrofolate deformylase activity
BLMD_07570	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BLMD_07575	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BLMD_07580	COG1764	response to oxidative stress
BLMD_07585	COG1846	Transcriptional regulator
BLMD_07590	COG1764	response to oxidative stress
BLMD_07600	COG0590	tRNA wobble adenosine to inosine editing
BLMD_07605	COG0406	alpha-ribazole phosphatase activity
BLMD_07620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BLMD_07625	COG1404	Belongs to the peptidase S8 family
BLMD_07630	COG2239	Acts as a magnesium transporter
BLMD_07640	COG0789	Transcriptional regulator
BLMD_07650	COG1846	Transcriptional regulator
BLMD_07655	COG1793	dna ligase
BLMD_07655	COG3285	dna ligase
BLMD_07660	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BLMD_07665	COG3300	MHYT domain
BLMD_07665	COG5001	Diguanylate cyclase
BLMD_07670	COG0586	Pfam SNARE associated Golgi protein
BLMD_07675	COG0861	Integral membrane protein TerC family
BLMD_07680	COG1191	sigma factor activity
BLMD_07700	COG0501	Belongs to the peptidase M48B family
BLMD_07705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLMD_07710	COG0768	penicillin binding
BLMD_07725	COG3594	Acyltransferase
BLMD_07730	COG5002	protein histidine kinase activity
BLMD_07735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BLMD_07740	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BLMD_07745	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BLMD_07750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BLMD_07755	COG0436	Aminotransferase
BLMD_07760	COG1850	ribulose-bisphosphate carboxylase activity
BLMD_07765	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BLMD_07765	COG0235	Class ii aldolase
BLMD_07770	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BLMD_07770	COG0235	Class ii aldolase
BLMD_07775	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BLMD_07780	COG0346	lactoylglutathione lyase activity
BLMD_07785	COG3339	Conserved Protein
BLMD_07795	COG3852	Histidine kinase
BLMD_07800	COG1846	Transcriptional regulator
BLMD_07805	COG1360	Flagellar Motor Protein
BLMD_07810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BLMD_07815	COG0542	response to heat
BLMD_07820	COG3949	Membrane
BLMD_07825	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BLMD_07830	COG0720	synthase
BLMD_07835	COG0602	queuosine metabolic process
BLMD_07840	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BLMD_07850	COG0457	Tetratricopeptide repeat
BLMD_07855	COG3739	integral membrane protein
BLMD_07860	COG3655	Transcriptional regulator
BLMD_07895	COG4873	Protein conserved in bacteria
BLMD_07905	COG3773	Cell wall hydrolase
BLMD_07910	COG2244	polysaccharide biosynthetic process
BLMD_07915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_07920	COG2217	Heavy metal translocating P-type atpase
BLMD_07925	COG0006	proline dipeptidase activity
BLMD_07935	COG1609	Transcriptional regulator
BLMD_07940	COG3711	transcriptional antiterminator
BLMD_07945	COG2190	(PTS) system
BLMD_07945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_07945	COG1263	PTS System
BLMD_07950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_07955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BLMD_07965	COG1533	DNA photolyase activity
BLMD_07970	COG0456	acetyltransferase
BLMD_07975	COG0840	transmembrane signaling receptor activity
BLMD_07980	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_07985	COG2084	Dehydrogenase
BLMD_07990	COG2340	Cysteine-rich secretory protein family
BLMD_07995	COG0768	penicillin binding
BLMD_08000	COG4191	Histidine kinase
BLMD_08005	COG0436	Aminotransferase
BLMD_08010	COG1714	RDD family
BLMD_08020	COG0784	Response regulator, receiver
BLMD_08020	COG0835	chemotaxis
BLMD_08030	COG2814	Major facilitator Superfamily
BLMD_08035	COG1376	ErfK ybiS ycfS ynhG family protein
BLMD_08040	COG1408	metallophosphoesterase
BLMD_08045	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_08050	COG2200	EAL domain
BLMD_08065	COG4703	Protein of unknown function (DUF1797)
BLMD_08070	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BLMD_08080	COG0517	IMP dehydrogenase activity
BLMD_08085	COG0583	DNA-binding transcription factor activity
BLMD_08090	COG0716	FMN binding
BLMD_08100	COG0716	FMN binding
BLMD_08105	COG2171	N-acyltransferase activity
BLMD_08110	COG1473	amidohydrolase
BLMD_08120	COG0450	alkyl hydroperoxide reductase
BLMD_08125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_08140	COG0746	molybdenum cofactor guanylyltransferase activity
BLMD_08145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BLMD_08150	COG0303	'Molybdopterin
BLMD_08155	COG1763	Mo-molybdopterin cofactor biosynthetic process
BLMD_08160	COG0314	molybdopterin synthase activity
BLMD_08165	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BLMD_08175	COG1132	(ABC) transporter
BLMD_08180	COG1132	(ABC) transporter
BLMD_08190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLMD_08195	COG1136	(ABC) transporter
BLMD_08200	COG0577	efflux transmembrane transporter activity
BLMD_08210	COG1349	DNA-binding transcription factor activity
BLMD_08215	COG1105	Belongs to the carbohydrate kinase PfkB family
BLMD_08220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_08220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLMD_08220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLMD_08240	COG0488	(ABC) transporter
BLMD_08250	COG2309	aminopeptidase activity
BLMD_08255	COG1077	Cell shape determining protein MreB Mrl
BLMD_08260	COG2002	toxin-antitoxin pair type II binding
BLMD_08265	COG3852	Histidine kinase
BLMD_08270	COG0569	domain protein
BLMD_08275	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BLMD_08280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLMD_08295	COG0561	phosphatase activity
BLMD_08300	COG0242	peptide deformylase activity
BLMD_08310	COG0497	DNA recombination
BLMD_08315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BLMD_08320	COG0022	dehydrogenase e1 component
BLMD_08325	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLMD_08330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLMD_08335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_08345	COG1982	Orn Lys Arg decarboxylase major
BLMD_08350	COG4476	Belongs to the UPF0223 family
BLMD_08355	COG4493	Belongs to the UPF0637 family
BLMD_08365	COG0483	inositol monophosphate 1-phosphatase activity
BLMD_08385	COG1595	DNA-templated transcription, initiation
BLMD_08410	COG1846	Transcriptional regulator
BLMD_08415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BLMD_08420	COG4896	Protein conserved in bacteria
BLMD_08430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BLMD_08435	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BLMD_08440	COG2066	Belongs to the glutaminase family
BLMD_08445	COG4838	Belongs to the UPF0358 family
BLMD_08450	COG0772	Belongs to the SEDS family
BLMD_08455	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BLMD_08460	COG1612	heme a metabolic process
BLMD_08465	COG0109	protoheme IX farnesyltransferase activity
BLMD_08470	COG2010	Cytochrome c
BLMD_08470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BLMD_08475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BLMD_08480	COG1845	cytochrome c oxidase, subunit III
BLMD_08485	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BLMD_08490	COG3336	cytochrome c oxidase
BLMD_08500	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BLMD_08505	COG2340	Cysteine-rich secretory protein family
BLMD_08520	COG3679	Belongs to the UPF0342 family
BLMD_08525	COG4471	UPF0298 protein
BLMD_08530	COG0742	ribosomal rna small subunit methyltransferase
BLMD_08535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BLMD_08540	COG3314	Sporulation integral membrane protein YlbJ
BLMD_08545	COG3480	Lon protease (S16) C-terminal proteolytic domain
BLMD_08550	COG1323	Belongs to the UPF0348 family
BLMD_08555	COG1399	metal-binding, possibly nucleic acid-binding protein
BLMD_08560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BLMD_08570	COG0454	-acetyltransferase
BLMD_08575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BLMD_08580	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BLMD_08585	COG2001	Belongs to the MraZ family
BLMD_08590	COG0275	rRNA processing
BLMD_08595	COG4839	cell division protein FtsL
BLMD_08605	COG0768	penicillin binding
BLMD_08610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BLMD_08615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLMD_08620	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BLMD_08625	COG0772	Belongs to the SEDS family
BLMD_08630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLMD_08635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BLMD_08640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BLMD_08645	COG3879	Bacterial protein of unknown function (DUF881)
BLMD_08650	COG3879	Bacterial protein of unknown function (DUF881)
BLMD_08655	COG3856	small basic protein
BLMD_08660	COG0849	cell division
BLMD_08665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BLMD_08670	COG1404	Belongs to the peptidase S8 family
BLMD_08670	COG4412	M6 family metalloprotease domain protein
BLMD_08675	COG4412	M6 family metalloprotease domain protein
BLMD_08675	COG1404	Belongs to the peptidase S8 family
BLMD_08685	COG1191	sigma factor activity
BLMD_08690	COG1191	sigma factor activity
BLMD_08695	COG1119	ATPase activity
BLMD_08700	COG0500	methyltransferase
BLMD_08705	COG1873	PFAM PRC-barrel domain
BLMD_08715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BLMD_08720	COG1799	cell septum assembly
BLMD_08725	COG0762	integral membrane protein
BLMD_08730	COG2302	S4 RNA-binding domain
BLMD_08735	COG3599	regulation of cell shape
BLMD_08740	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BLMD_08745	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BLMD_08750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BLMD_08755	COG0564	pseudouridine synthase activity
BLMD_08760	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BLMD_08765	COG2233	PERMEase
BLMD_08770	COG0540	Belongs to the ATCase OTCase family
BLMD_08775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BLMD_08780	COG0505	Belongs to the CarA family
BLMD_08785	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BLMD_08790	COG0543	2 iron, 2 sulfur cluster binding
BLMD_08795	COG0167	dihydroorotate dehydrogenase activity
BLMD_08800	COG0284	orotidine-5'-phosphate decarboxylase activity
BLMD_08805	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BLMD_08815	COG0175	sulfate reduction
BLMD_08820	COG0306	phosphate transporter
BLMD_08825	COG2046	Belongs to the sulfate adenylyltransferase family
BLMD_08830	COG0529	Catalyzes the synthesis of activated sulfate
BLMD_08835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BLMD_08840	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BLMD_08845	COG1648	precorrin-2 dehydrogenase activity
BLMD_08855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BLMD_08860	COG1561	YicC-like family, N-terminal region
BLMD_08865	COG2052	Domain of unknown function (DUF370)
BLMD_08870	COG0194	GDP metabolic process
BLMD_08875	COG1758	RNA polymerase activity
BLMD_08880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BLMD_08885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BLMD_08890	COG0242	peptide deformylase activity
BLMD_08895	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BLMD_08900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLMD_08900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BLMD_08905	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BLMD_08910	COG0631	protein serine/threonine phosphatase activity
BLMD_08915	COG2815	serine threonine protein kinase
BLMD_08915	COG0515	serine threonine protein kinase
BLMD_08920	COG1162	GTPase activity
BLMD_08925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BLMD_08930	COG1564	THIamine pyrophosphokinase
BLMD_08940	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BLMD_08945	COG1302	Protein conserved in bacteria
BLMD_08950	COG1461	Dihydroxyacetone kinase
BLMD_08955	COG1760	l-serine dehydratase
BLMD_08960	COG1760	l-serine dehydratase
BLMD_08965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BLMD_08970	COG1349	DNA-binding transcription factor activity
BLMD_08975	COG0416	fatty acid biosynthetic process
BLMD_08980	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BLMD_08985	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_08990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLMD_08995	COG0571	ribonuclease III activity
BLMD_09000	COG1196	nuclear chromosome segregation
BLMD_09005	COG0552	protein localization to endoplasmic reticulum
BLMD_09010	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BLMD_09015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BLMD_09020	COG0228	four-way junction DNA binding
BLMD_09025	COG1837	Belongs to the UPF0109 family
BLMD_09035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BLMD_09040	COG0336	Belongs to the RNA methyltransferase TrmD family
BLMD_09045	COG0335	large ribosomal subunit rRNA binding
BLMD_09050	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BLMD_09055	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLMD_09065	COG2257	FlhB HrpN YscU SpaS Family
BLMD_09070	COG0045	succinate-CoA ligase (ADP-forming) activity
BLMD_09075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BLMD_09080	COG0758	DNA mediated transformation
BLMD_09085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLMD_09090	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BLMD_09095	COG4974	Belongs to the 'phage' integrase family
BLMD_09100	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BLMD_09105	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BLMD_09110	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BLMD_09115	COG1815	bacterial-type flagellum-dependent cell motility
BLMD_09120	COG1558	bacterial-type flagellum-dependent cell motility
BLMD_09125	COG1677	Flagellar hook-basal body complex protein FliE
BLMD_09130	COG1766	The M ring may be actively involved in energy transduction
BLMD_09135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLMD_09140	COG1317	bacterial-type flagellum organization
BLMD_09145	COG1157	protein secretion by the type III secretion system
BLMD_09150	COG2882	bacterial-type flagellum organization
BLMD_09155	COG3334	PFAM MgtE intracellular
BLMD_09160	COG3144	bacterial-type flagellum assembly
BLMD_09165	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BLMD_09170	COG4786	Flagellar basal body rod
BLMD_09175	COG1582	Flagellar protein (FlbD)
BLMD_09180	COG1580	Controls the rotational direction of flagella during chemotaxis
BLMD_09185	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLMD_09190	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLMD_09190	COG1776	CheC inhibitor of MCP methylation
BLMD_09195	COG2201	protein-glutamate methylesterase activity
BLMD_09200	COG3190	flagellar
BLMD_09205	COG1338	Plays a role in the flagellum-specific transport system
BLMD_09210	COG1987	bacterial-type flagellum assembly
BLMD_09215	COG1684	flagellar biosynthetic protein fliR
BLMD_09220	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BLMD_09225	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BLMD_09230	COG1419	protein localization to endoplasmic reticulum
BLMD_09235	COG0455	bacterial-type flagellum organization
BLMD_09240	COG2201	protein-glutamate methylesterase activity
BLMD_09245	COG0643	Histidine kinase
BLMD_09245	COG2198	Histidine kinase
BLMD_09250	COG0835	chemotaxis
BLMD_09255	COG1776	CheC inhibitor of MCP methylation
BLMD_09260	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BLMD_09265	COG1191	sigma factor activity
BLMD_09275	COG0052	Belongs to the universal ribosomal protein uS2 family
BLMD_09280	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BLMD_09285	COG0528	UMP kinase activity
BLMD_09290	COG0233	cytoplasmic translational termination
BLMD_09295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BLMD_09300	COG4589	Belongs to the CDS family
BLMD_09305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BLMD_09310	COG0750	zinc metalloprotease
BLMD_09315	COG0442	prolyl-tRNA aminoacylation
BLMD_09320	COG2176	DNA-directed DNA polymerase activity
BLMD_09345	COG0779	Required for maturation of 30S ribosomal subunits
BLMD_09350	COG0195	Participates in both transcription termination and antitermination
BLMD_09355	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BLMD_09360	COG1358	cellular component organization or biogenesis
BLMD_09365	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BLMD_09370	COG1550	Protein conserved in bacteria
BLMD_09375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BLMD_09380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BLMD_09385	COG0196	riboflavin kinase activity
BLMD_09390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BLMD_09395	COG1185	polyribonucleotide nucleotidyltransferase activity
BLMD_09400	COG0726	polysaccharide deacetylase
BLMD_09405	COG0612	Peptidase, M16
BLMD_09410	COG1873	PFAM PRC-barrel domain
BLMD_09415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLMD_09420	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BLMD_09425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BLMD_09430	COG0527	aspartate kinase activity
BLMD_09440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLMD_09445	COG0740	serine-type endopeptidase activity
BLMD_09455	COG1674	ftsk spoiiie
BLMD_09455	COG4980	gas vesicle protein
BLMD_09460	COG2188	Transcriptional regulator
BLMD_09465	COG2814	Major facilitator Superfamily
BLMD_09470	COG0612	Peptidase, M16
BLMD_09475	COG0612	Peptidase, M16
BLMD_09480	COG0300	oxidoreductase activity
BLMD_09495	COG1426	Protein conserved in bacteria
BLMD_09500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BLMD_09505	COG1058	Belongs to the CinA family
BLMD_09505	COG1546	Belongs to the CinA family
BLMD_09510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BLMD_09515	COG1418	mRNA catabolic process
BLMD_09520	COG1692	metallophosphoesterase
BLMD_09525	COG2359	stage V sporulation protein S
BLMD_09535	COG1063	alcohol dehydrogenase
BLMD_09540	COG0156	8-amino-7-oxononanoate synthase activity
BLMD_09545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BLMD_09550	COG4550	Control of competence regulator ComK, YlbF/YmcA
BLMD_09560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BLMD_09565	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BLMD_09570	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BLMD_09595	COG0457	Tetratricopeptide repeat
BLMD_09610	COG0523	cobalamin synthesis protein
BLMD_09635	COG3619	membrane
BLMD_09640	COG3263	regulation of cellular component size
BLMD_09645	COG2814	Major facilitator Superfamily
BLMD_09655	COG0393	Putative heavy-metal-binding
BLMD_09660	COG0398	Pfam SNARE associated Golgi protein
BLMD_09665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLMD_09670	COG1819	glycosyl
BLMD_09675	COG0531	amino acid
BLMD_09680	COG5577	PFAM Coat F domain
BLMD_09690	COG1388	LysM domain
BLMD_09690	COG3858	chitin binding
BLMD_09695	COG1309	transcriptional regulator
BLMD_09700	COG3631	Ketosteroid isomerase-related protein
BLMD_09705	COG0702	epimerase
BLMD_09715	COG1764	response to oxidative stress
BLMD_09720	COG2076	Multidrug Resistance protein
BLMD_09725	COG2076	Multidrug Resistance protein
BLMD_09740	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BLMD_09745	COG1923	regulation of RNA biosynthetic process
BLMD_09760	COG1780	Probably involved in ribonucleotide reductase function
BLMD_09765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLMD_09770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLMD_09775	COG4112	unkown
BLMD_09790	COG0735	belongs to the Fur family
BLMD_09795	COG1802	Transcriptional regulator
BLMD_09800	COG0697	spore germination
BLMD_09840	COG1309	transcriptional regulator
BLMD_09875	COG4282	regulation of fungal-type cell wall biogenesis
BLMD_09880	COG5444	nuclease activity
BLMD_09905	COG2814	Major facilitator Superfamily
BLMD_09910	COG0457	Tetratricopeptide repeat
BLMD_09920	COG4413	Urea transporter
BLMD_09930	COG0832	Belongs to the urease beta subunit family
BLMD_09940	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BLMD_09945	COG0830	nickel cation binding
BLMD_09950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BLMD_09955	COG0829	nickel cation binding
BLMD_09965	COG1695	Transcriptional regulator
BLMD_09985	COG0464	growth
BLMD_09990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BLMD_09995	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BLMD_10000	COG0789	Transcriptional regulator
BLMD_10005	COG0174	glutamine synthetase
BLMD_10035	COG0174	glutamine synthetase
BLMD_10065	COG0490	domain, Protein
BLMD_10070	COG0475	glutathione-regulated potassium exporter activity
BLMD_10080	COG1073	alpha beta
BLMD_10120	COG1309	transcriptional regulator
BLMD_10125	COG2076	Multidrug Resistance protein
BLMD_10130	COG2076	Multidrug Resistance protein
BLMD_10135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLMD_10155	COG3546	catalase activity
BLMD_10180	COG1846	Transcriptional regulator
BLMD_10185	COG0346	lactoylglutathione lyase activity
BLMD_10190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BLMD_10195	COG0655	NAD(P)H dehydrogenase (quinone) activity
BLMD_10210	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BLMD_10220	COG3209	COG3209 Rhs family protein
BLMD_10230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BLMD_10235	COG1388	LysM domain
BLMD_10240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BLMD_10245	COG4224	UPF0291 protein
BLMD_10250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BLMD_10260	COG3763	UPF0154 protein
BLMD_10270	COG0785	Cytochrome C biogenesis protein
BLMD_10275	COG2201	protein-glutamate methylesterase activity
BLMD_10280	COG4846	Membrane protein involved in cytochrome C biogenesis
BLMD_10290	COG0071	Belongs to the small heat shock protein (HSP20) family
BLMD_10305	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BLMD_10310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_10330	COG0824	Thioesterase
BLMD_10350	COG4841	protein insertion into membrane
BLMD_10355	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BLMD_10360	COG1832	CoA-binding protein
BLMD_10365	COG0187	DNA topoisomerase II activity
BLMD_10370	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLMD_10375	COG1609	Transcriptional regulator
BLMD_10390	COG2160	L-arabinose isomerase activity
BLMD_10410	COG1115	amino acid carrier protein
BLMD_10420	COG2181	nitrate reductase activity
BLMD_10425	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BLMD_10430	COG1140	nitrate reductase beta subunit
BLMD_10435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BLMD_10455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BLMD_10465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BLMD_10470	COG2223	nitrite transmembrane transporter activity
BLMD_10490	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BLMD_10500	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BLMD_10530	COG0477	Major facilitator Superfamily
BLMD_10535	COG3420	alginic acid biosynthetic process
BLMD_10540	COG1114	Component of the transport system for branched-chain amino acids
BLMD_10550	COG1687	branched-chain amino acid
BLMD_10555	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BLMD_10560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_10590	COG1024	Enoyl-CoA hydratase
BLMD_10595	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_10600	COG2084	Dehydrogenase
BLMD_10605	COG1960	acyl-CoA dehydrogenase activity
BLMD_10610	COG1482	cell wall glycoprotein biosynthetic process
BLMD_10615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLMD_10615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_10615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLMD_10625	COG0582	viral genome integration into host DNA
BLMD_10645	COG3711	transcriptional antiterminator
BLMD_10645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_10660	COG1725	Transcriptional regulator
BLMD_10665	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_10670	COG1312	Catalyzes the dehydration of D-mannonate
BLMD_10685	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BLMD_10695	COG1609	Transcriptional regulator
BLMD_10700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLMD_10705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BLMD_10710	COG0640	Transcriptional regulator
BLMD_10715	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BLMD_10730	COG1649	PFAM Uncharacterised BCR, COG1649
BLMD_10735	COG2404	hydrolase activity, acting on ester bonds
BLMD_10740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BLMD_10750	COG0438	transferase activity, transferring glycosyl groups
BLMD_10755	COG2027	D-alanyl-D-alanine carboxypeptidase
BLMD_10775	COG1309	transcriptional regulator
BLMD_10780	COG1252	NADH dehydrogenase
BLMD_10795	COG0166	Belongs to the GPI family
BLMD_10805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLMD_10810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BLMD_10815	COG1024	Enoyl-CoA hydratase
BLMD_10820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLMD_10825	COG0511	ligase activity, forming carbon-carbon bonds
BLMD_10830	COG0439	Biotin carboxylase
BLMD_10835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_10835	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BLMD_10840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_10845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_10850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_10855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_10860	COG0318	PFAM AMP-dependent synthetase and ligase
BLMD_10865	COG1960	acyl-CoA dehydrogenase activity
BLMD_10870	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLMD_10875	COG1733	regulation of RNA biosynthetic process
BLMD_10880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BLMD_10885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BLMD_10895	COG2323	membrane
BLMD_10900	COG0306	phosphate transporter
BLMD_10905	COG0175	sulfate reduction
BLMD_10910	COG1809	phosphosulfolactate synthase activity
BLMD_10915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_10920	COG4948	Mandelate Racemase Muconate Lactonizing
BLMD_10925	COG2814	Major facilitator Superfamily
BLMD_10930	COG0463	Glycosyl transferase, family 2
BLMD_10945	COG0493	'glutamate synthase
BLMD_10950	COG0069	glutamate synthase activity
BLMD_10950	COG0067	glutamate synthase
BLMD_10950	COG0070	glutamate synthase
BLMD_10955	COG0583	DNA-binding transcription factor activity
BLMD_10980	COG1132	(ABC) transporter
BLMD_10990	COG0300	oxidoreductase activity
BLMD_10995	COG0574	Belongs to the PEP-utilizing enzyme family
BLMD_10995	COG3848	Pyruvate phosphate dikinase
BLMD_11000	COG0477	Major facilitator Superfamily
BLMD_11005	COG0243	molybdopterin cofactor binding
BLMD_11010	COG1846	Transcriptional regulator
BLMD_11015	COG2814	Major facilitator Superfamily
BLMD_11020	COG0531	amino acid
BLMD_11030	COG0531	amino acid
BLMD_11035	COG0531	amino acid
BLMD_11040	COG0697	spore germination
BLMD_11050	COG0840	transmembrane signaling receptor activity
BLMD_11055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLMD_11060	COG1404	Belongs to the peptidase S8 family
BLMD_11070	COG1309	transcriptional regulator
BLMD_11075	COG1846	Transcriptional regulator
BLMD_11105	COG1309	transcriptional regulator
BLMD_11110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_11115	COG3708	Transcriptional regulator
BLMD_11125	COG2378	regulation of single-species biofilm formation
BLMD_11135	COG0640	Transcriptional regulator
BLMD_11140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_11150	COG0531	amino acid
BLMD_11155	COG0741	lytic transglycosylase activity
BLMD_11160	COG1086	Polysaccharide biosynthesis protein
BLMD_11175	COG0438	transferase activity, transferring glycosyl groups
BLMD_11180	COG2322	membrane
BLMD_11195	COG1619	proteins homologs of microcin C7 resistance protein MccF
BLMD_11200	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLMD_11205	COG3584	3D domain protein
BLMD_11205	COG1388	LysM domain
BLMD_11210	COG0514	ATP-dependent DNA helicase (RecQ)
BLMD_11230	COG2315	Protein conserved in bacteria
BLMD_11235	COG5444	nuclease activity
BLMD_11240	COG2427	Protein of unknown function (DUF1641)
BLMD_11245	COG3383	formate dehydrogenase (NAD+) activity
BLMD_11260	COG5444	nuclease activity
BLMD_11270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLMD_11285	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BLMD_11290	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BLMD_11320	COG2350	Protein conserved in bacteria
BLMD_11345	COG0402	S-adenosylhomocysteine deaminase activity
BLMD_11360	COG2267	carboxylic ester hydrolase activity
BLMD_11375	COG1280	lysine exporter protein (LysE YggA)
BLMD_11385	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLMD_11395	COG0574	Belongs to the PEP-utilizing enzyme family
BLMD_11395	COG3848	Pyruvate phosphate dikinase
BLMD_11415	COG2318	DinB family
BLMD_11420	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BLMD_11445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BLMD_11460	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_11480	COG1657	PFAM Prenyltransferase squalene oxidase
BLMD_11485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BLMD_11495	COG0733	neurotransmitter:sodium symporter activity
BLMD_11500	COG0385	Bile acid
BLMD_11505	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLMD_11510	COG0567	Dehydrogenase, E1 component
BLMD_11515	COG4548	von Willebrand factor, type A
BLMD_11520	COG0714	Associated with various cellular activities
BLMD_11525	COG2032	superoxide dismutase activity
BLMD_11530	COG1388	LysM domain
BLMD_11530	COG0791	NLP P60 protein
BLMD_11540	COG0534	Mate efflux family protein
BLMD_11545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BLMD_11550	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BLMD_11560	COG2962	Rard protein
BLMD_11570	COG4305	rare lipoprotein A
BLMD_11585	COG1733	regulation of RNA biosynthetic process
BLMD_11590	COG0778	Nitroreductase
BLMD_11595	COG0400	carboxylic ester hydrolase activity
BLMD_11605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLMD_11610	COG3409	Peptidoglycan-binding domain 1 protein
BLMD_11610	COG0793	Belongs to the peptidase S41A family
BLMD_11615	COG2226	methyltransferase
BLMD_11625	COG1876	peptidase activity
BLMD_11630	COG0813	purine-nucleoside phosphorylase activity
BLMD_11635	COG0701	Predicted permease
BLMD_11650	COG0671	phosphoesterase, PA-phosphatase related
BLMD_11665	COG4479	Belongs to the UPF0346 family
BLMD_11675	COG1509	lysine 2,3-aminomutase activity
BLMD_11680	COG0456	acetyltransferase
BLMD_11685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLMD_11690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BLMD_11695	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BLMD_11700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BLMD_11715	COG0456	acetyltransferase
BLMD_11730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLMD_11735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLMD_11740	COG1846	Transcriptional regulator
BLMD_11750	COG3706	GGDEF domain
BLMD_11755	COG0534	Mate efflux family protein
BLMD_11770	COG4698	Protein conserved in bacteria
BLMD_11775	COG2755	lipolytic protein G-D-S-L family
BLMD_11780	COG1999	signal sequence binding
BLMD_11800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BLMD_11805	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BLMD_11810	COG1272	protein, Hemolysin III
BLMD_11815	COG0204	Acyl-transferase
BLMD_11820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BLMD_11830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BLMD_11840	COG2136	Putative SAM-dependent methyltransferase
BLMD_11840	COG2521	methyltransferase
BLMD_11850	COG0129	dihydroxy-acid dehydratase activity
BLMD_11855	COG1413	lyase activity
BLMD_11865	COG0386	Belongs to the glutathione peroxidase family
BLMD_11870	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BLMD_11875	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BLMD_11880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLMD_11890	COG1278	Cold shock
BLMD_11910	COG0328	RNA-DNA hybrid ribonuclease activity
BLMD_11915	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BLMD_11920	COG0328	RNA-DNA hybrid ribonuclease activity
BLMD_11930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLMD_11940	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BLMD_11950	COG1755	Isoprenylcysteine carboxyl methyltransferase
BLMD_11955	COG3424	synthase
BLMD_11965	COG2233	PERMEase
BLMD_11970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLMD_11975	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BLMD_11980	COG1199	ATP-dependent helicase activity
BLMD_12000	COG0116	Belongs to the methyltransferase superfamily
BLMD_12010	COG3599	regulation of cell shape
BLMD_12015	COG4474	Belongs to the UPF0398 family
BLMD_12025	COG3359	exonuclease
BLMD_12030	COG1111	helicase
BLMD_12030	COG1205	dead DEAH box helicase
BLMD_12035	COG2190	(PTS) system
BLMD_12040	COG0071	Belongs to the small heat shock protein (HSP20) family
BLMD_12075	COG3331	DNA recombination
BLMD_12080	COG4499	WXG100 protein secretion system (Wss), protein YukC
BLMD_12080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLMD_12090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BLMD_12095	COG3935	DnaD domain protein
BLMD_12100	COG0017	Asparaginyl-tRNA synthetase
BLMD_12105	COG0436	Aminotransferase
BLMD_12110	COG5353	protein conserved in bacteria
BLMD_12120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BLMD_12120	COG1199	ATP-dependent helicase activity
BLMD_12125	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BLMD_12130	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BLMD_12135	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BLMD_12145	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BLMD_12145	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BLMD_12150	COG0617	tRNA 3'-terminal CCA addition
BLMD_12155	COG0438	transferase activity, transferring glycosyl groups
BLMD_12160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BLMD_12165	COG1803	Methylglyoxal synthase
BLMD_12170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BLMD_12175	COG1694	Mazg nucleotide pyrophosphohydrolase
BLMD_12180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_12190	COG4347	Protein of unknown function (DUF1405)
BLMD_12195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BLMD_12195	COG2010	Cytochrome c
BLMD_12200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BLMD_12205	COG0723	plastoquinol--plastocyanin reductase activity
BLMD_12215	COG5582	Belongs to the UPF0302 family
BLMD_12220	COG0457	Tetratricopeptide repeat
BLMD_12225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BLMD_12230	COG0287	Prephenate dehydrogenase
BLMD_12235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BLMD_12240	COG0159	tryptophan synthase activity
BLMD_12245	COG0133	tryptophan synthase activity
BLMD_12250	COG0135	phosphoribosylanthranilate isomerase activity
BLMD_12255	COG0134	indole-3-glycerol-phosphate synthase activity
BLMD_12260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BLMD_12265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLMD_12270	COG4401	Chorismate mutase type I
BLMD_12275	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BLMD_12280	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BLMD_12285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BLMD_12290	COG0105	UTP biosynthetic process
BLMD_12295	COG0142	geranyltranstransferase activity
BLMD_12300	COG2226	methyltransferase
BLMD_12305	COG0142	geranyltranstransferase activity
BLMD_12320	COG0776	regulation of translation
BLMD_12325	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BLMD_12345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BLMD_12350	COG1160	GTP binding
BLMD_12375	COG1304	FMN binding
BLMD_12380	COG0539	negative regulation of cytoplasmic translation
BLMD_12385	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BLMD_12390	COG2959	enzyme of heme biosynthesis
BLMD_12395	COG3773	Cell wall hydrolase
BLMD_12395	COG3409	Peptidoglycan-binding domain 1 protein
BLMD_12400	COG2339	peptidase activity
BLMD_12410	COG0492	ferredoxin-NADP+ reductase activity
BLMD_12415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BLMD_12420	COG4862	establishment of competence for transformation
BLMD_12425	COG1408	metallophosphoesterase
BLMD_12435	COG1388	LysM domain
BLMD_12440	COG1266	CAAX protease self-immunity
BLMD_12445	COG0514	ATP-dependent DNA helicase (RecQ)
BLMD_12450	COG4955	Helix-turn-helix domain
BLMD_12455	COG1141	Ferredoxin
BLMD_12460	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BLMD_12465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BLMD_12470	COG0739	heme binding
BLMD_12480	COG1595	DNA-templated transcription, initiation
BLMD_12500	COG5002	protein histidine kinase activity
BLMD_12505	COG0745	RESPONSE REGULATOR receiver
BLMD_12510	COG5002	protein histidine kinase activity
BLMD_12515	COG0745	RESPONSE REGULATOR receiver
BLMD_12520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BLMD_12525	COG1333	cytochrome c biogenesis protein
BLMD_12530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_12535	COG1187	pseudouridine synthase activity
BLMD_12540	COG0700	Nucleoside recognition
BLMD_12545	COG2715	membrane protein required for spore maturation
BLMD_12550	COG1686	Belongs to the peptidase S11 family
BLMD_12560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BLMD_12565	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BLMD_12575	COG1547	Domain of unknown function (DUF309)
BLMD_12580	COG0456	acetyltransferase
BLMD_12585	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BLMD_12590	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BLMD_12590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BLMD_12595	COG0307	riboflavin synthase, alpha
BLMD_12600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BLMD_12600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BLMD_12620	COG0457	Tetratricopeptide repeat
BLMD_12625	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BLMD_12635	COG4086	secreted protein
BLMD_12640	COG4195	phage-related replication protein
BLMD_12650	COG0019	diaminopimelate decarboxylase activity
BLMD_12660	COG0697	spore germination
BLMD_12675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLMD_12700	COG2172	sigma factor antagonist activity
BLMD_12710	COG1686	Belongs to the peptidase S11 family
BLMD_12715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BLMD_12720	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BLMD_12725	COG4974	Belongs to the 'phage' integrase family
BLMD_12735	COG0735	belongs to the Fur family
BLMD_12740	COG1300	Membrane
BLMD_12745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_12755	COG1953	Uracil, thiamine, allantoin
BLMD_12775	COG2153	protein acetylation
BLMD_12780	COG1379	DNA repair
BLMD_12785	COG0494	nUDIX hydrolase
BLMD_12795	COG1309	transcriptional regulator
BLMD_12805	COG0667	Aldo Keto reductase
BLMD_12815	COG1073	alpha beta
BLMD_12825	COG4918	Iron-sulphur cluster biosynthesis
BLMD_12835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BLMD_12835	COG0456	acetyltransferase
BLMD_12840	COG2329	Antibiotic biosynthesis monooxygenase
BLMD_12845	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BLMD_12855	COG0747	negative chemotaxis
BLMD_12860	COG0601	transmembrane transport
BLMD_12865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLMD_12870	COG0444	Belongs to the ABC transporter superfamily
BLMD_12880	COG0534	Mate efflux family protein
BLMD_12895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLMD_12905	COG2211	Major facilitator Superfamily
BLMD_12910	COG0346	lactoylglutathione lyase activity
BLMD_12915	COG1072	(Pantothenic acid kinase))
BLMD_12925	COG3842	ATPase activity
BLMD_12950	COG2205	protein histidine kinase activity
BLMD_12955	COG0745	RESPONSE REGULATOR receiver
BLMD_12980	COG2814	Major facilitator Superfamily
BLMD_12990	COG4195	phage-related replication protein
BLMD_13005	COG0457	Tetratricopeptide repeat
BLMD_13025	COG5444	nuclease activity
BLMD_13030	COG0300	oxidoreductase activity
BLMD_13035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_13040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLMD_13045	COG4187	Peptidase family M20/M25/M40
BLMD_13050	COG1902	pentaerythritol trinitrate reductase activity
BLMD_13055	COG0596	Alpha beta hydrolase
BLMD_13060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BLMD_13065	COG1234	tRNA 3'-trailer cleavage
BLMD_13070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BLMD_13090	COG2188	Transcriptional regulator
BLMD_13095	COG2723	6-phospho-beta-galactosidase activity
BLMD_13100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_13105	COG1447	Phosphotransferase system cellobiose-specific component IIA
BLMD_13110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_13115	COG1785	Belongs to the alkaline phosphatase family
BLMD_13120	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_13125	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BLMD_13130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLMD_13140	COG0706	membrane insertase activity
BLMD_13145	COG2195	Cleaves the N-terminal amino acid of tripeptides
BLMD_13150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BLMD_13155	COG4129	membrane
BLMD_13160	COG1126	abc transporter atp-binding protein
BLMD_13165	COG0765	amino acid transport
BLMD_13170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLMD_13180	COG1597	lipid kinase activity
BLMD_13185	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLMD_13190	COG0022	dehydrogenase e1 component
BLMD_13195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BLMD_13200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLMD_13205	COG3426	butyrate kinase activity
BLMD_13215	COG0280	phosphate acetyltransferase
BLMD_13220	COG3290	protein histidine kinase activity
BLMD_13220	COG3829	transcription factor binding
BLMD_13230	COG0584	glycerophosphoryl diester phosphodiesterase
BLMD_13235	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLMD_13250	COG0745	RESPONSE REGULATOR receiver
BLMD_13255	COG0750	zinc metalloprotease
BLMD_13260	COG0497	DNA recombination
BLMD_13265	COG1438	arginine binding
BLMD_13270	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BLMD_13275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BLMD_13280	COG0142	geranyltranstransferase activity
BLMD_13285	COG1722	exodeoxyribonuclease VII activity
BLMD_13290	COG1570	exodeoxyribonuclease VII activity
BLMD_13295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BLMD_13300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLMD_13305	COG1302	Protein conserved in bacteria
BLMD_13310	COG0439	Biotin carboxylase
BLMD_13315	COG0511	ligase activity, forming carbon-carbon bonds
BLMD_13355	COG3854	ATPases associated with a variety of cellular activities
BLMD_13365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BLMD_13370	COG0006	proline dipeptidase activity
BLMD_13375	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BLMD_13385	COG3872	metal-dependent enzyme
BLMD_13395	COG1752	Esterase of the alpha-beta hydrolase superfamily
BLMD_13400	COG1321	iron dependent repressor
BLMD_13405	COG0095	Lipoate-protein ligase
BLMD_13410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLMD_13415	COG2113	Glycine betaine
BLMD_13420	COG4176	ABC-type proline glycine betaine transport system permease component
BLMD_13425	COG4175	Glycine betaine
BLMD_13425	COG0517	IMP dehydrogenase activity
BLMD_13430	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BLMD_13435	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BLMD_13440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BLMD_13450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BLMD_13475	COG0681	Belongs to the peptidase S26 family
BLMD_13500	COG4940	Competence protein ComGF
BLMD_13510	COG4970	Tfp pilus assembly protein FimT
BLMD_13515	COG4537	Required for transformation and DNA binding
BLMD_13520	COG1459	type II secretion system
BLMD_13525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BLMD_13530	COG1366	Belongs to the anti-sigma-factor antagonist family
BLMD_13540	COG1393	Belongs to the ArsC family
BLMD_13550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_13560	COG0011	TIGRFAM Protein of
BLMD_13570	COG2866	Carboxypeptidase
BLMD_13575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_13580	COG1368	sulfuric ester hydrolase activity
BLMD_13585	COG1940	carbohydrate kinase activity
BLMD_13590	COG4483	Protein conserved in bacteria
BLMD_13595	COG0697	spore germination
BLMD_13600	COG0705	Rhomboid family
BLMD_13600	COG0457	Tetratricopeptide repeat
BLMD_13605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BLMD_13610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BLMD_13615	COG0438	transferase activity, transferring glycosyl groups
BLMD_13630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BLMD_13635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BLMD_13640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BLMD_13645	COG0581	inorganic phosphate transmembrane transporter activity
BLMD_13650	COG0573	inorganic phosphate transmembrane transporter activity
BLMD_13655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BLMD_13665	COG0477	Major facilitator Superfamily
BLMD_13675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BLMD_13680	COG2839	Protein conserved in bacteria
BLMD_13685	COG5521	maltodextrose utilization protein MalA
BLMD_13690	COG1388	LysM domain
BLMD_13695	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BLMD_13700	COG4709	membrane
BLMD_13705	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BLMD_13710	COG0735	belongs to the Fur family
BLMD_13715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BLMD_13720	COG1121	(ABC) transporter
BLMD_13725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_13735	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BLMD_13740	COG0513	Belongs to the DEAD box helicase family
BLMD_13750	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BLMD_13755	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BLMD_13760	COG2384	SAM-dependent methyltransferase
BLMD_13785	COG5444	nuclease activity
BLMD_13800	COG2010	Cytochrome c
BLMD_13805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BLMD_13810	COG0358	DNA primase activity
BLMD_13815	COG1671	Belongs to the UPF0178 family
BLMD_13820	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BLMD_13825	COG0517	IMP dehydrogenase activity
BLMD_13830	COG0751	glycine-tRNA ligase activity
BLMD_13835	COG0752	glycyl-tRNA synthetase alpha subunit
BLMD_13840	COG1381	Involved in DNA repair and RecF pathway recombination
BLMD_13850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BLMD_13855	COG0295	cytidine deaminase activity
BLMD_13860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BLMD_13865	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BLMD_13870	COG1480	7TM receptor with intracellular HD hydrolase
BLMD_13875	COG1702	phosphate starvation-inducible protein PhoH
BLMD_13880	COG0561	phosphatase activity
BLMD_13895	COG4864	UPF0365 protein
BLMD_13900	COG1030	water channel activity
BLMD_13905	COG1610	YqeY-like protein
BLMD_13910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BLMD_13915	COG1283	sodium-dependent phosphate transmembrane transporter activity
BLMD_13920	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BLMD_13925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BLMD_13930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BLMD_13935	COG2264	protein methyltransferase activity
BLMD_13940	COG0484	heat shock protein binding
BLMD_13945	COG0443	Heat shock 70 kDa protein
BLMD_13950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BLMD_13955	COG1420	regulation of RNA biosynthetic process
BLMD_13960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BLMD_13965	COG0481	GTPase activity
BLMD_13975	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLMD_13980	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BLMD_13985	COG0268	Binds directly to 16S ribosomal RNA
BLMD_13995	COG1733	regulation of RNA biosynthetic process
BLMD_14000	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLMD_14005	COG1466	dna polymerase III delta subunit
BLMD_14015	COG0658	competence protein
BLMD_14015	COG2333	competence protein COMEC
BLMD_14020	COG2131	deaminase
BLMD_14025	COG1596	polysaccharide export
BLMD_14025	COG1555	photosystem II stabilization
BLMD_14030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLMD_14035	COG2226	methyltransferase
BLMD_14040	COG0799	negative regulation of ribosome biogenesis
BLMD_14045	COG1713	HD superfamily hydrolase involved in NAD metabolism
BLMD_14050	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BLMD_14055	COG1534	Rna-binding protein
BLMD_14060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BLMD_14065	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BLMD_14070	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BLMD_14080	COG2755	lipolytic protein G-D-S-L family
BLMD_14090	COG5609	conserved protein (DUF2294)
BLMD_14095	COG3383	formate dehydrogenase (NAD+) activity
BLMD_14100	COG2427	Protein of unknown function (DUF1641)
BLMD_14140	COG2723	6-phospho-beta-galactosidase activity
BLMD_14145	COG1447	Phosphotransferase system cellobiose-specific component IIA
BLMD_14150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_14170	COG1486	melibiose metabolic process
BLMD_14185	COG4978	Transcriptional regulator
BLMD_14185	COG0789	Transcriptional regulator
BLMD_14200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BLMD_14205	COG2828	Protein conserved in bacteria
BLMD_14215	COG2181	nitrate reductase activity
BLMD_14220	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BLMD_14225	COG1140	nitrate reductase beta subunit
BLMD_14230	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BLMD_14235	COG2223	nitrite transmembrane transporter activity
BLMD_14245	COG3226	Transcriptional regulator
BLMD_14280	COG2197	response regulator
BLMD_14285	COG4585	Histidine kinase
BLMD_14290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_14295	COG0730	response to heat
BLMD_14300	COG0425	Belongs to the sulfur carrier protein TusA family
BLMD_14305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLMD_14305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_14310	COG0425	Belongs to the sulfur carrier protein TusA family
BLMD_14310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLMD_14315	COG2210	Belongs to the sulfur carrier protein TusA family
BLMD_14320	COG1937	Protein conserved in bacteria
BLMD_14345	COG1942	4-Oxalocrotonate Tautomerase
BLMD_14350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BLMD_14355	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BLMD_14360	COG1733	regulation of RNA biosynthetic process
BLMD_14365	COG3239	Fatty acid desaturase
BLMD_14370	COG4585	Histidine kinase
BLMD_14375	COG2197	response regulator
BLMD_14380	COG0492	ferredoxin-NADP+ reductase activity
BLMD_14385	COG0747	negative chemotaxis
BLMD_14395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLMD_14400	COG0444	Belongs to the ABC transporter superfamily
BLMD_14405	COG4608	Belongs to the ABC transporter superfamily
BLMD_14425	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_14435	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BLMD_14450	COG2124	cytochrome p450
BLMD_14455	COG0730	response to heat
BLMD_14465	COG3507	Belongs to the glycosyl hydrolase 43 family
BLMD_14470	COG2211	Major facilitator Superfamily
BLMD_14480	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_14485	COG1621	beta-fructofuranosidase activity
BLMD_14490	COG3716	PTS system mannose fructose sorbose family IID component
BLMD_14495	COG3715	PTS system
BLMD_14500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_14505	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_14510	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BLMD_14510	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BLMD_14530	COG2169	Transcriptional regulator
BLMD_14535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BLMD_14540	COG2205	protein histidine kinase activity
BLMD_14565	COG0656	L-ascorbic acid biosynthetic process
BLMD_14570	COG2814	Major facilitator Superfamily
BLMD_14575	COG1733	regulation of RNA biosynthetic process
BLMD_14580	COG3340	Belongs to the peptidase S51 family
BLMD_14585	COG1587	Uroporphyrinogen-III synthase
BLMD_14595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_14600	COG0583	DNA-binding transcription factor activity
BLMD_14605	COG2814	Major facilitator Superfamily
BLMD_14615	COG2124	cytochrome p450
BLMD_14615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BLMD_14620	COG1309	transcriptional regulator
BLMD_14625	COG1404	Belongs to the peptidase S8 family
BLMD_14630	COG2226	methyltransferase
BLMD_14650	COG0626	cystathionine gamma-synthase activity
BLMD_14655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLMD_14660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BLMD_14665	COG2226	methyltransferase
BLMD_14680	COG0768	penicillin binding
BLMD_14685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BLMD_14690	COG0572	uridine kinase
BLMD_14710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BLMD_14715	COG3906	Belongs to the UPF0473 family
BLMD_14720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BLMD_14725	COG4472	Bacterial protein of unknown function (DUF965)
BLMD_14730	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BLMD_14735	COG0628	permease
BLMD_14750	COG3881	PFAM PRC-barrel domain
BLMD_14755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BLMD_14760	COG0457	Tetratricopeptide repeat
BLMD_14765	COG0482	sulfurtransferase activity
BLMD_14770	COG1104	cysteine desulfurase activity
BLMD_14775	COG1959	2 iron, 2 sulfur cluster binding
BLMD_14780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BLMD_14785	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BLMD_14795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BLMD_14800	COG0124	histidyl-tRNA synthetase
BLMD_14805	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLMD_14805	COG4991	sh3 domain protein
BLMD_14805	COG3103	Sh3 type 3 domain protein
BLMD_14810	COG1490	D-aminoacyl-tRNA deacylase activity
BLMD_14815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BLMD_14820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLMD_14825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BLMD_14825	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BLMD_14830	COG5416	Lipopolysaccharide assembly protein A domain
BLMD_14835	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BLMD_14835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BLMD_14845	COG2244	polysaccharide biosynthetic process
BLMD_14850	COG2323	membrane
BLMD_14860	COG1862	Preprotein translocase
BLMD_14865	COG0343	queuine tRNA-ribosyltransferase activity
BLMD_14870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BLMD_14880	COG2255	four-way junction helicase activity
BLMD_14885	COG0632	four-way junction helicase activity
BLMD_14895	COG2112	serine threonine protein kinase
BLMD_14905	COG2318	DinB family
BLMD_14910	COG4195	phage-related replication protein
BLMD_14925	COG0217	transcriptional regulatory protein
BLMD_14935	COG1388	LysM domain
BLMD_14940	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BLMD_14945	COG0157	Belongs to the NadC ModD family
BLMD_14950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BLMD_14955	COG1104	cysteine desulfurase activity
BLMD_14960	COG1827	regulation of RNA biosynthetic process
BLMD_14965	COG0077	Prephenate dehydratase
BLMD_14970	COG4492	Belongs to the UPF0735 family
BLMD_14975	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BLMD_14980	COG3290	protein histidine kinase activity
BLMD_14985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BLMD_14990	COG2868	ribosomal protein
BLMD_14995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BLMD_15000	COG1994	Peptidase M50
BLMD_15005	COG0739	heme binding
BLMD_15010	COG3832	glyoxalase III activity
BLMD_15015	COG0640	Transcriptional regulator
BLMD_15020	COG2894	cell division
BLMD_15025	COG0850	regulation of cytokinetic process
BLMD_15030	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BLMD_15035	COG1792	Involved in formation and maintenance of cell shape
BLMD_15040	COG1077	Cell shape determining protein MreB Mrl
BLMD_15045	COG2003	Belongs to the UPF0758 family
BLMD_15050	COG0424	maF-like protein
BLMD_15060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BLMD_15065	COG0285	dihydrofolate synthase activity
BLMD_15070	COG0525	valine-tRNA ligase activity
BLMD_15080	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BLMD_15085	COG1388	LysM domain
BLMD_15090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BLMD_15095	COG0113	porphobilinogen synthase activity
BLMD_15100	COG1587	Uroporphyrinogen-III synthase
BLMD_15105	COG0181	hydroxymethylbilane synthase activity
BLMD_15110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BLMD_15115	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BLMD_15125	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BLMD_15130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BLMD_15135	COG0470	DNA polymerase III
BLMD_15135	COG1067	ATP-dependent peptidase activity
BLMD_15140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BLMD_15145	COG0544	peptidyl-prolyl cis-trans isomerase activity
BLMD_15150	COG1477	protein flavinylation
BLMD_15150	COG0457	Tetratricopeptide repeat
BLMD_15155	COG0066	3-isopropylmalate dehydratase activity
BLMD_15160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BLMD_15165	COG0473	3-isopropylmalate dehydrogenase activity
BLMD_15170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLMD_15175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BLMD_15180	COG0440	acetolactate synthase activity
BLMD_15185	COG0028	Belongs to the TPP enzyme family
BLMD_15190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLMD_15200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BLMD_15220	COG0622	Phosphoesterase
BLMD_15225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BLMD_15230	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BLMD_15235	COG5401	PFAM Sporulation and spore germination
BLMD_15240	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BLMD_15245	COG1846	Transcriptional regulator
BLMD_15250	COG2197	response regulator
BLMD_15255	COG4221	oxidoreductase activity
BLMD_15260	COG0824	Thioesterase
BLMD_15265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BLMD_15270	COG1053	succinate dehydrogenase
BLMD_15275	COG2009	succinate dehydrogenase
BLMD_15280	COG1719	4-vinyl reductase, 4VR
BLMD_15285	COG0527	aspartate kinase activity
BLMD_15290	COG0322	excinuclease ABC activity
BLMD_15295	COG3118	belongs to the thioredoxin family
BLMD_15300	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BLMD_15305	COG2086	electron transfer activity
BLMD_15310	COG1024	Enoyl-CoA hydratase
BLMD_15315	COG1309	transcriptional regulator
BLMD_15320	COG0318	PFAM AMP-dependent synthetase and ligase
BLMD_15325	COG3766	membrane
BLMD_15330	COG1193	negative regulation of DNA recombination
BLMD_15335	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BLMD_15335	COG1796	DNA polymerase
BLMD_15340	COG1286	toxin biosynthetic process
BLMD_15345	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BLMD_15350	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLMD_15370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLMD_15370	COG0072	phenylalanine-tRNA ligase activity
BLMD_15375	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BLMD_15380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLMD_15390	COG1966	Carbon starvation protein
BLMD_15395	COG1309	transcriptional regulator
BLMD_15400	COG3402	PFAM membrane-flanked domain
BLMD_15420	COG0395	ABC-type sugar transport system, permease component
BLMD_15425	COG1175	transmembrane transport
BLMD_15430	COG1653	transport
BLMD_15435	COG0371	Dehydrogenase
BLMD_15440	COG0235	Class ii aldolase
BLMD_15445	COG1069	ribulokinase activity
BLMD_15450	COG2160	L-arabinose isomerase activity
BLMD_15455	COG3507	Belongs to the glycosyl hydrolase 43 family
BLMD_15460	COG1363	Peptidase, m42
BLMD_15470	COG3326	Membrane
BLMD_15475	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BLMD_15480	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BLMD_15485	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BLMD_15490	COG1346	cytolysis
BLMD_15500	COG3540	Alkaline phosphatase
BLMD_15505	COG3279	Response regulator of the LytR AlgR family
BLMD_15510	COG3275	phosphorelay sensor kinase activity
BLMD_15525	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BLMD_15535	COG0398	Pfam SNARE associated Golgi protein
BLMD_15540	COG1484	DNA-dependent DNA replication
BLMD_15545	COG3611	Membrane attachment protein
BLMD_15550	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BLMD_15565	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BLMD_15570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BLMD_15575	COG3866	Pectate lyase
BLMD_15580	COG0237	dephospho-CoA kinase activity
BLMD_15585	COG1971	Probably functions as a manganese efflux pump
BLMD_15590	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BLMD_15595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLMD_15595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLMD_15600	COG5002	protein histidine kinase activity
BLMD_15605	COG0745	RESPONSE REGULATOR receiver
BLMD_15610	COG0039	L-malate dehydrogenase activity
BLMD_15615	COG0538	isocitrate dehydrogenase activity
BLMD_15620	COG0372	Belongs to the citrate synthase family
BLMD_15630	COG2273	Hydrolase Family 16
BLMD_15635	COG2707	UPF0756 membrane protein
BLMD_15640	COG0628	permease
BLMD_15645	COG3030	protein affecting phage T7 exclusion by the F plasmid
BLMD_15655	COG0205	6-phosphofructokinase activity
BLMD_15660	COG0825	malonyl-CoA metabolic process
BLMD_15665	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BLMD_15670	COG0281	malic enzyme
BLMD_15675	COG0587	DNA-directed DNA polymerase activity
BLMD_15695	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BLMD_15705	COG4109	DRTGG domain
BLMD_15710	COG1695	Transcriptional regulator
BLMD_15715	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BLMD_15720	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_15725	COG0165	Argininosuccinate lyase
BLMD_15730	COG0137	argininosuccinate synthase activity
BLMD_15735	COG0521	Mo-molybdopterin cofactor biosynthetic process
BLMD_15740	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BLMD_15745	COG0827	DNA restriction-modification system
BLMD_15750	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BLMD_15755	COG3874	Sporulation protein YtfJ
BLMD_15765	COG1714	RDD family
BLMD_15770	COG0616	signal peptide processing
BLMD_15775	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BLMD_15780	COG1846	Transcriptional regulator
BLMD_15785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLMD_15795	COG0301	tRNA thio-modification
BLMD_15800	COG1104	cysteine desulfurase activity
BLMD_15805	COG1114	Component of the transport system for branched-chain amino acids
BLMD_15810	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BLMD_15815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BLMD_15820	COG1309	transcriptional regulator
BLMD_15825	COG1956	GAF domain-containing protein
BLMD_15830	COG2199	diguanylate cyclase activity
BLMD_15830	COG2203	Gaf domain
BLMD_15835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BLMD_15850	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BLMD_15855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLMD_15860	COG0454	-acetyltransferase
BLMD_15865	COG0517	IMP dehydrogenase activity
BLMD_15870	COG0123	including yeast histone deacetylase and acetoin utilization protein
BLMD_15875	COG1360	Flagellar Motor Protein
BLMD_15880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BLMD_15885	COG1609	Transcriptional regulator
BLMD_15890	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BLMD_15890	COG1605	Chorismate mutase
BLMD_15900	COG3118	belongs to the thioredoxin family
BLMD_15905	COG4980	gas vesicle protein
BLMD_15910	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BLMD_15915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BLMD_15920	COG1674	ftsk spoiiie
BLMD_15925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLMD_15930	COG4848	Belongs to the UPF0354 family
BLMD_15935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_15945	COG1363	Peptidase, m42
BLMD_15950	COG5584	Small secreted protein
BLMD_15955	COG0281	malic enzyme
BLMD_15960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_15965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BLMD_15975	COG0510	thiamine kinase activity
BLMD_15980	COG1523	belongs to the glycosyl hydrolase 13 family
BLMD_15985	COG1597	lipid kinase activity
BLMD_15995	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BLMD_16000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLMD_16015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLMD_16020	COG2252	PERMEase
BLMD_16025	COG4473	ABC transporter
BLMD_16030	COG1131	(ABC) transporter
BLMD_16035	COG1349	DNA-binding transcription factor activity
BLMD_16040	COG1187	pseudouridine synthase activity
BLMD_16045	COG2244	polysaccharide biosynthetic process
BLMD_16050	COG2081	HI0933 family
BLMD_16055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BLMD_16065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLMD_16080	COG5578	integral membrane protein
BLMD_16085	COG0673	inositol 2-dehydrogenase activity
BLMD_16090	COG1653	transport
BLMD_16095	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BLMD_16100	COG4209	transmembrane transport
BLMD_16105	COG2207	Transcriptional regulator
BLMD_16110	COG1653	transport
BLMD_16115	COG0395	ABC-type sugar transport system, permease component
BLMD_16120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLMD_16125	COG1073	alpha beta
BLMD_16135	COG0583	DNA-binding transcription factor activity
BLMD_16140	COG0346	lactoylglutathione lyase activity
BLMD_16145	COG0495	leucyl-tRNA aminoacylation
BLMD_16155	COG2814	Major facilitator Superfamily
BLMD_16160	COG1464	Belongs to the NlpA lipoprotein family
BLMD_16165	COG2433	Pfam Transposase IS66
BLMD_16170	COG0577	efflux transmembrane transporter activity
BLMD_16175	COG1136	(ABC) transporter
BLMD_16185	COG1131	(ABC) transporter
BLMD_16190	COG1725	Transcriptional regulator
BLMD_16200	COG1242	4 iron, 4 sulfur cluster binding
BLMD_16205	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BLMD_16215	COG2267	carboxylic ester hydrolase activity
BLMD_16220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BLMD_16225	COG0671	phosphoesterase, PA-phosphatase related
BLMD_16230	COG0438	transferase activity, transferring glycosyl groups
BLMD_16230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLMD_16235	COG0367	asparagine synthase
BLMD_16240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BLMD_16245	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BLMD_16260	COG1506	peptidase
BLMD_16265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BLMD_16270	COG1116	anion transmembrane transporter activity
BLMD_16275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLMD_16280	COG0494	nUDIX hydrolase
BLMD_16290	COG4824	toxin secretion phage lysis holin
BLMD_16295	COG0783	Belongs to the Dps family
BLMD_16310	COG1854	S-ribosylhomocysteine lyase activity
BLMD_16315	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BLMD_16320	COG0288	reversible hydration of carbon dioxide
BLMD_16325	COG0523	cobalamin synthesis protein
BLMD_16330	COG0803	Belongs to the bacterial solute-binding protein 9 family
BLMD_16335	COG0254	rRNA binding
BLMD_16340	COG1271	oxidase subunit
BLMD_16345	COG1294	oxidase, subunit
BLMD_16360	COG4948	Mandelate Racemase Muconate Lactonizing
BLMD_16365	COG0318	PFAM AMP-dependent synthetase and ligase
BLMD_16370	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BLMD_16375	COG0596	Alpha beta hydrolase
BLMD_16380	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BLMD_16385	COG1169	isochorismate synthase
BLMD_16390	COG1575	Belongs to the MenA family. Type 1 subfamily
BLMD_16395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BLMD_16400	COG0058	SHG alpha-glucan phosphorylase activity
BLMD_16405	COG0297	glycogen (starch) synthase activity
BLMD_16410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BLMD_16415	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BLMD_16420	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BLMD_16545	COG1609	Transcriptional regulator
BLMD_16550	COG3859	Proton-coupled thiamine transporter YuaJ
BLMD_16555	COG3764	Sortase (surface protein transpeptidase)
BLMD_16570	COG0457	Tetratricopeptide repeat
BLMD_16575	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BLMD_16580	COG0569	domain protein
BLMD_16585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLMD_16595	COG2318	DinB family
BLMD_16605	COG1454	alcohol dehydrogenase
BLMD_16615	COG1510	regulation of RNA biosynthetic process
BLMD_16625	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BLMD_16630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BLMD_16645	COG1397	ADP-ribosylglycohydrolase
BLMD_16740	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BLMD_16750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLMD_16755	COG0726	polysaccharide deacetylase
BLMD_16760	COG1408	metallophosphoesterase
BLMD_16765	COG1968	undecaprenyl-diphosphatase activity
BLMD_16770	COG0628	permease
BLMD_16775	COG0673	inositol 2-dehydrogenase activity
BLMD_16780	COG0693	protein deglycase activity
BLMD_16785	COG0840	transmembrane signaling receptor activity
BLMD_16790	COG0840	transmembrane signaling receptor activity
BLMD_16795	COG0840	transmembrane signaling receptor activity
BLMD_16805	COG2070	2-Nitropropane dioxygenase
BLMD_16810	COG0432	Pfam Uncharacterised protein family UPF0047
BLMD_16815	COG0366	Alpha amylase catalytic
BLMD_16830	COG5297	Belongs to the glycosyl hydrolase family 6
BLMD_16835	COG1253	flavin adenine dinucleotide binding
BLMD_16840	COG2738	Putative neutral zinc metallopeptidase
BLMD_16855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BLMD_16865	COG2323	membrane
BLMD_16870	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BLMD_16880	COG0166	Belongs to the GPI family
BLMD_16885	COG1979	alcohol dehydrogenase
BLMD_16890	COG2155	Conserved Protein
BLMD_16895	COG1098	S1 RNA binding domain
BLMD_16900	COG0436	Aminotransferase
BLMD_16905	COG1522	sequence-specific DNA binding
BLMD_16910	COG2267	carboxylic ester hydrolase activity
BLMD_16925	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BLMD_16940	COG5018	Exonuclease
BLMD_16945	COG2814	Major facilitator Superfamily
BLMD_16950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLMD_16955	COG3011	Protein conserved in bacteria
BLMD_16965	COG3290	protein histidine kinase activity
BLMD_16970	COG4565	transcriptional regulatory protein
BLMD_16980	COG1183	phosphatidylcholine synthase activity
BLMD_16985	COG0586	Pfam SNARE associated Golgi protein
BLMD_16990	COG0688	phosphatidylethanolamine metabolic process
BLMD_16995	COG3493	citrate carrier protein
BLMD_17005	COG2111	Na H antiporter
BLMD_17005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BLMD_17010	COG2111	Na H antiporter
BLMD_17015	COG1006	Multisubunit Na H antiporter MnhC subunit
BLMD_17020	COG0651	ATP synthesis coupled electron transport
BLMD_17025	COG1863	multisubunit Na H antiporter MnhE subunit
BLMD_17030	COG2212	antiporter activity
BLMD_17035	COG1320	monovalent cation:proton antiporter activity
BLMD_17040	COG2050	protein possibly involved in aromatic compounds catabolism
BLMD_17045	COG2197	response regulator
BLMD_17060	COG0142	geranyltranstransferase activity
BLMD_17080	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BLMD_17085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BLMD_17090	COG1335	isochorismatase
BLMD_17095	COG5506	Protein of unknown function (DUF1694)
BLMD_17110	COG0628	permease
BLMD_17115	COG1959	2 iron, 2 sulfur cluster binding
BLMD_17130	COG1418	mRNA catabolic process
BLMD_17135	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_17150	COG1511	domain protein
BLMD_17155	COG0433	COG0433 Predicted ATPase
BLMD_17155	COG1674	ftsk spoiiie
BLMD_17160	COG4499	WXG100 protein secretion system (Wss), protein YukC
BLMD_17165	COG5417	Belongs to the EsaB family
BLMD_17170	COG4842	Belongs to the WXG100 family
BLMD_17175	COG1115	amino acid carrier protein
BLMD_17180	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BLMD_17180	COG2508	Transcriptional regulator
BLMD_17185	COG0686	Belongs to the AlaDH PNT family
BLMD_17195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BLMD_17200	COG1268	BioY protein
BLMD_17205	COG2056	Na+-H+ antiporter family
BLMD_17210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BLMD_17215	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BLMD_17220	COG3584	3D domain protein
BLMD_17230	COG1252	NADH dehydrogenase
BLMD_17235	COG0492	ferredoxin-NADP+ reductase activity
BLMD_17250	COG0456	acetyltransferase
BLMD_17255	COG0316	Belongs to the HesB IscA family
BLMD_17260	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BLMD_17265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BLMD_17270	COG4844	belongs to the
BLMD_17275	COG1252	NADH dehydrogenase
BLMD_17280	COG5646	InterPro IPR014922
BLMD_17295	COG0457	Tetratricopeptide repeat
BLMD_17300	COG3479	Phenolic acid decarboxylase
BLMD_17310	COG4837	Protein of unknown function (DUF1462)
BLMD_17315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BLMD_17320	COG1506	peptidase
BLMD_17320	COG4946	Tricorn protease homolog
BLMD_17320	COG0823	Involved in the tonB-independent uptake of proteins
BLMD_17325	COG0083	homoserine kinase activity
BLMD_17330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BLMD_17335	COG0460	homoserine dehydrogenase
BLMD_17340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLMD_17345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BLMD_17350	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BLMD_17355	COG0647	UMP catabolic process
BLMD_17360	COG2445	Protein of unknown function DUF86
BLMD_17365	COG4470	Protein conserved in bacteria
BLMD_17380	COG0739	heme binding
BLMD_17390	COG0733	neurotransmitter:sodium symporter activity
BLMD_17400	COG3377	Domain of unknown function (DUF1805)
BLMD_17405	COG0737	Belongs to the 5'-nucleotidase family
BLMD_17410	COG0730	response to heat
BLMD_17415	COG1801	Protein of unknown function DUF72
BLMD_17425	COG3226	Transcriptional regulator
BLMD_17430	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BLMD_17435	COG2508	Transcriptional regulator
BLMD_17440	COG2814	Major facilitator Superfamily
BLMD_17445	COG1288	antiporter activity
BLMD_17460	COG2356	endonuclease I
BLMD_17470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BLMD_17485	COG0457	Tetratricopeptide repeat
BLMD_17495	COG0719	Fe-S assembly protein
BLMD_17500	COG0822	iron-sulfur transferase activity
BLMD_17505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BLMD_17510	COG0719	Fe-S assembly protein
BLMD_17515	COG0396	ATPase activity
BLMD_17525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BLMD_17530	COG1464	Belongs to the NlpA lipoprotein family
BLMD_17535	COG2011	ABC-type metal ion transport system permease component
BLMD_17540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BLMD_17550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_17555	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BLMD_17565	COG0509	glycine decarboxylation via glycine cleavage system
BLMD_17570	COG1393	Belongs to the ArsC family
BLMD_17575	COG1960	acyl-CoA dehydrogenase activity
BLMD_17580	COG0183	Belongs to the thiolase family
BLMD_17585	COG1250	3-hydroxyacyl-CoA dehydrogenase
BLMD_17585	COG1024	Enoyl-CoA hydratase
BLMD_17600	COG5577	PFAM Coat F domain
BLMD_17615	COG1120	ATPase activity
BLMD_17620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_17625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_17630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_17645	COG1686	Belongs to the peptidase S11 family
BLMD_17650	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_17655	COG0783	Belongs to the Dps family
BLMD_17660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLMD_17665	COG0745	RESPONSE REGULATOR receiver
BLMD_17670	COG2770	Histidine kinase
BLMD_17670	COG2205	protein histidine kinase activity
BLMD_17675	COG1309	transcriptional regulator
BLMD_17680	COG0114	fumarate hydratase activity
BLMD_17690	COG0697	spore germination
BLMD_17695	COG0814	amino acid
BLMD_17710	COG2197	response regulator
BLMD_17715	COG4585	Histidine kinase
BLMD_17720	COG4758	membrane
BLMD_17730	COG1842	Phage shock protein A
BLMD_17735	COG4758	membrane
BLMD_17740	COG4677	pectinesterase activity
BLMD_17745	COG2096	Adenosyltransferase
BLMD_17750	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_17755	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BLMD_17760	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BLMD_17775	COG1454	alcohol dehydrogenase
BLMD_17780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLMD_17785	COG1120	ATPase activity
BLMD_17790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_17795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_17800	COG1802	Transcriptional regulator
BLMD_17805	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_17810	COG2258	MOSC domain
BLMD_17815	COG0583	DNA-binding transcription factor activity
BLMD_17825	COG2721	sulfolactate sulfo-lyase activity
BLMD_17830	COG0246	Mannitol dehydrogenase
BLMD_17835	COG1609	Transcriptional regulator
BLMD_17840	COG2211	Major facilitator Superfamily
BLMD_17845	COG1904	glucuronate isomerase
BLMD_17850	COG2205	protein histidine kinase activity
BLMD_17855	COG0745	RESPONSE REGULATOR receiver
BLMD_17860	COG1120	ATPase activity
BLMD_17865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_17870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_17875	COG0531	amino acid
BLMD_17885	COG1988	membrane-bound metal-dependent
BLMD_17890	COG1368	sulfuric ester hydrolase activity
BLMD_17895	COG2814	Major facilitator Superfamily
BLMD_17900	COG0656	L-ascorbic acid biosynthetic process
BLMD_17905	COG1940	carbohydrate kinase activity
BLMD_17910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BLMD_17920	COG0596	Alpha beta hydrolase
BLMD_17925	COG3973	AAA domain
BLMD_17930	COG2860	membrane
BLMD_17935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BLMD_17935	COG0456	acetyltransferase
BLMD_17940	COG0456	acetyltransferase
BLMD_17945	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BLMD_17950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BLMD_17955	COG2217	Heavy metal translocating P-type atpase
BLMD_17960	COG1653	transport
BLMD_17965	COG1175	transmembrane transport
BLMD_17970	COG0395	ABC-type sugar transport system, permease component
BLMD_17975	COG1501	Belongs to the glycosyl hydrolase 31 family
BLMD_17980	COG1472	Belongs to the glycosyl hydrolase 3 family
BLMD_17985	COG1121	(ABC) transporter
BLMD_17990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BLMD_17995	COG0803	Belongs to the bacterial solute-binding protein 9 family
BLMD_18015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_18015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLMD_18015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLMD_18020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_18030	COG2217	Heavy metal translocating P-type atpase
BLMD_18035	COG2608	mercury ion transmembrane transporter activity
BLMD_18040	COG1937	Protein conserved in bacteria
BLMD_18045	COG0693	protein deglycase activity
BLMD_18050	COG1349	DNA-binding transcription factor activity
BLMD_18055	COG1070	Carbohydrate kinase
BLMD_18060	COG4952	isomerase
BLMD_18070	COG3347	Dehydrogenase
BLMD_18070	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_18075	COG2814	Major facilitator Superfamily
BLMD_18080	COG2814	Major facilitator Superfamily
BLMD_18090	COG2124	cytochrome p450
BLMD_18100	COG1846	Transcriptional regulator
BLMD_18110	COG0673	inositol 2-dehydrogenase activity
BLMD_18115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BLMD_18130	COG1191	sigma factor activity
BLMD_18140	COG2140	Oxalate decarboxylase
BLMD_18160	COG5520	Belongs to the glycosyl hydrolase 30 family
BLMD_18165	COG3507	Belongs to the glycosyl hydrolase 43 family
BLMD_18180	COG5444	nuclease activity
BLMD_18200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BLMD_18205	COG0557	exoribonuclease II activity
BLMD_18210	COG1647	Serine aminopeptidase, S33
BLMD_18215	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BLMD_18220	COG2002	toxin-antitoxin pair type II binding
BLMD_18225	COG1476	TRANSCRIPTIONal
BLMD_18230	COG1396	sequence-specific DNA binding
BLMD_18235	COG1396	sequence-specific DNA binding
BLMD_18240	COG1174	glycine betaine transport
BLMD_18245	COG1732	Glycine betaine
BLMD_18250	COG1174	glycine betaine transport
BLMD_18255	COG0517	IMP dehydrogenase activity
BLMD_18255	COG1125	glycine betaine transport
BLMD_18260	COG1510	regulation of RNA biosynthetic process
BLMD_18265	COG2095	MarC family integral membrane protein
BLMD_18270	COG3064	Membrane
BLMD_18275	COG4640	response to antibiotic
BLMD_18280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_18295	COG0693	protein deglycase activity
BLMD_18300	COG0148	phosphopyruvate hydratase activity
BLMD_18305	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BLMD_18310	COG0149	triose-phosphate isomerase activity
BLMD_18315	COG0126	phosphoglycerate kinase activity
BLMD_18320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BLMD_18325	COG2390	Transcriptional regulator
BLMD_18330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLMD_18335	COG1113	amino acid transport
BLMD_18360	COG1556	Lactate utilization protein
BLMD_18365	COG1139	Iron-sulfur cluster binding protein
BLMD_18370	COG0247	lactate metabolic process
BLMD_18375	COG2186	Transcriptional regulator
BLMD_18380	COG1620	l-lactate permease
BLMD_18385	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BLMD_18395	COG5039	Polysaccharide pyruvyl transferase
BLMD_18400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BLMD_18405	COG0110	maltose O-acetyltransferase activity
BLMD_18410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BLMD_18415	COG2244	polysaccharide biosynthetic process
BLMD_18420	COG1216	Glycosyl transferase, family 2
BLMD_18425	COG5039	Polysaccharide pyruvyl transferase
BLMD_18430	COG1216	Glycosyl transferase, family 2
BLMD_18440	COG0438	transferase activity, transferring glycosyl groups
BLMD_18445	COG1215	transferase activity, transferring glycosyl groups
BLMD_18450	COG0438	transferase activity, transferring glycosyl groups
BLMD_18455	COG1086	Polysaccharide biosynthesis protein
BLMD_18460	COG0489	protein tyrosine kinase activity
BLMD_18465	COG3944	biosynthesis protein
BLMD_18470	COG1396	sequence-specific DNA binding
BLMD_18475	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLMD_18480	COG2271	Major facilitator Superfamily
BLMD_18490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BLMD_18500	COG1454	alcohol dehydrogenase
BLMD_18505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLMD_18515	COG1733	regulation of RNA biosynthetic process
BLMD_18520	COG1902	pentaerythritol trinitrate reductase activity
BLMD_18525	COG1621	beta-fructofuranosidase activity
BLMD_18530	COG1621	beta-fructofuranosidase activity
BLMD_18545	COG0740	serine-type endopeptidase activity
BLMD_18550	COG1611	Belongs to the LOG family
BLMD_18555	COG1694	Mazg nucleotide pyrophosphohydrolase
BLMD_18560	COG1078	dGTPase activity
BLMD_18565	COG0659	secondary active sulfate transmembrane transporter activity
BLMD_18570	COG0288	reversible hydration of carbon dioxide
BLMD_18575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLMD_18580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BLMD_18585	COG0640	Transcriptional regulator
BLMD_18595	COG2732	(Barnase) inhibitor
BLMD_18600	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BLMD_18605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_18610	COG1481	regulation of sporulation
BLMD_18615	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BLMD_18620	COG1660	Displays ATPase and GTPase activities
BLMD_18625	COG1051	belongs to the nudix hydrolase family
BLMD_18635	COG0492	ferredoxin-NADP+ reductase activity
BLMD_18640	COG0457	Tetratricopeptide repeat
BLMD_18645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLMD_18650	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BLMD_18650	COG0140	phosphoribosyl-ATP diphosphatase activity
BLMD_18655	COG0107	imidazoleglycerol-phosphate synthase activity
BLMD_18660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BLMD_18665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BLMD_18670	COG0131	Imidazoleglycerol-phosphate dehydratase
BLMD_18675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BLMD_18680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BLMD_18685	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BLMD_18690	COG4990	cell redox homeostasis
BLMD_18695	COG5297	Belongs to the glycosyl hydrolase family 6
BLMD_18700	COG0110	maltose O-acetyltransferase activity
BLMD_18705	COG0546	phosphoglycolate phosphatase activity
BLMD_18710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BLMD_18715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BLMD_18720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BLMD_18725	COG1846	Transcriptional regulator
BLMD_18730	COG2814	Major facilitator Superfamily
BLMD_18735	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BLMD_18740	COG1950	PFAM Membrane protein of
BLMD_18745	COG1983	PspC domain protein
BLMD_18750	COG3595	metallopeptidase activity
BLMD_18770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BLMD_18775	COG0556	nucleotide-excision repair
BLMD_18780	COG4897	Protein conserved in bacteria
BLMD_18790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLMD_18800	COG0793	Belongs to the peptidase S41A family
BLMD_18800	COG3409	Peptidoglycan-binding domain 1 protein
BLMD_18805	COG0473	3-isopropylmalate dehydrogenase activity
BLMD_18810	COG3883	PFAM NLP P60 protein
BLMD_18810	COG0791	NLP P60 protein
BLMD_18815	COG2177	Part of the ABC transporter FtsEX involved in
BLMD_18820	COG2884	Cell division ATP-binding protein ftsE
BLMD_18830	COG2010	Cytochrome c
BLMD_18835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_18840	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BLMD_18845	COG0653	protein targeting
BLMD_18850	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BLMD_18865	COG1516	flagellar protein fliS
BLMD_18870	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BLMD_18875	COG1334	flagellar protein FlaG
BLMD_18885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BLMD_18890	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BLMD_18895	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BLMD_18905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BLMD_18910	COG4786	Flagellar basal body rod
BLMD_18910	COG1256	bacterial-type flagellum assembly
BLMD_18915	COG3418	PFAM FlgN family protein
BLMD_18920	COG2747	anti-sigma28 factor FlgM
BLMD_18930	COG1040	competence protein
BLMD_18940	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BLMD_18945	COG1307	EDD domain protein, DegV family
BLMD_18950	COG2197	response regulator
BLMD_18955	COG4585	Histidine kinase
BLMD_18960	COG1739	Uncharacterized protein family UPF0029
BLMD_18965	COG1316	TRANSCRIPTIONal
BLMD_18975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLMD_18980	COG0438	transferase activity, transferring glycosyl groups
BLMD_18985	COG1215	transferase activity, transferring glycosyl groups
BLMD_18990	COG3206	protein involved in exopolysaccharide biosynthesis
BLMD_18995	COG3307	-O-antigen
BLMD_19000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLMD_19005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BLMD_19010	COG0297	glycogen (starch) synthase activity
BLMD_19010	COG0438	transferase activity, transferring glycosyl groups
BLMD_19015	COG2244	polysaccharide biosynthetic process
BLMD_19025	COG2247	cell wall binding repeat
BLMD_19025	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLMD_19030	COG2247	cell wall binding repeat
BLMD_19030	COG2385	sporulation resulting in formation of a cellular spore
BLMD_19040	COG1316	TRANSCRIPTIONal
BLMD_19050	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BLMD_19055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BLMD_19075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLMD_19095	COG1134	teichoic acid transport
BLMD_19100	COG1682	transport, permease protein
BLMD_19105	COG0463	Glycosyl transferase, family 2
BLMD_19105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLMD_19110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLMD_19115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BLMD_19120	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BLMD_19125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLMD_19130	COG4193	domain, Protein
BLMD_19135	COG1482	cell wall glycoprotein biosynthetic process
BLMD_19155	COG0800	Aldolase
BLMD_19160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLMD_19165	COG1609	Transcriptional regulator
BLMD_19170	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BLMD_19175	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_19180	COG1063	alcohol dehydrogenase
BLMD_19185	COG2814	Major facilitator Superfamily
BLMD_19190	COG1316	TRANSCRIPTIONal
BLMD_19195	COG0561	phosphatase activity
BLMD_19200	COG0791	NLP P60 protein
BLMD_19205	COG2843	Capsule synthesis protein
BLMD_19215	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BLMD_19220	COG1609	Transcriptional regulator
BLMD_19225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLMD_19230	COG1869	D-ribose catabolic process
BLMD_19235	COG1129	ABC transporter
BLMD_19240	COG1172	Belongs to the binding-protein-dependent transport system permease family
BLMD_19245	COG1879	ABC-type sugar transport system periplasmic component
BLMD_19250	COG0583	DNA-binding transcription factor activity
BLMD_19255	COG2226	methyltransferase
BLMD_19260	COG3527	Alpha-acetolactate decarboxylase
BLMD_19265	COG0028	Belongs to the TPP enzyme family
BLMD_19270	COG0583	DNA-binding transcription factor activity
BLMD_19275	COG0405	Gamma-glutamyltransferase
BLMD_19280	COG1522	sequence-specific DNA binding
BLMD_19285	COG2059	Chromate
BLMD_19290	COG2059	Chromate
BLMD_19295	COG4464	protein tyrosine phosphatase activity
BLMD_19300	COG3944	biosynthesis protein
BLMD_19305	COG4715	Zinc finger, swim domain protein
BLMD_19310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BLMD_19320	COG3878	Protein conserved in bacteria
BLMD_19340	COG0561	phosphatase activity
BLMD_19345	COG1349	DNA-binding transcription factor activity
BLMD_19355	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_19365	COG3732	PTS system glucitol sorbitol-specific
BLMD_19385	COG0629	single-stranded DNA binding
BLMD_19400	COG1970	mechanosensitive ion channel activity
BLMD_19405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BLMD_19410	COG4786	Flagellar basal body rod
BLMD_19415	COG4786	Flagellar basal body rod
BLMD_19420	COG1077	Cell shape determining protein MreB Mrl
BLMD_19425	COG1609	Transcriptional regulator
BLMD_19435	COG1846	Transcriptional regulator
BLMD_19440	COG2814	Major facilitator Superfamily
BLMD_19445	COG0671	phosphoesterase, PA-phosphatase related
BLMD_19450	COG1227	inorganic diphosphatase activity
BLMD_19455	COG3546	catalase activity
BLMD_19460	COG3361	conserved protein (COG2071)
BLMD_19475	COG0517	IMP dehydrogenase activity
BLMD_19480	COG0598	Magnesium transport protein CorA
BLMD_19485	COG1253	flavin adenine dinucleotide binding
BLMD_19495	COG0347	Belongs to the P(II) protein family
BLMD_19505	COG0740	serine-type endopeptidase activity
BLMD_19515	COG0739	heme binding
BLMD_19520	COG1247	-acetyltransferase
BLMD_19530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLMD_19535	COG0477	Major facilitator Superfamily
BLMD_19540	COG3251	PFAM MbtH domain protein
BLMD_19545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_19550	COG3433	isochorismatase activity
BLMD_19550	COG1535	isochorismatase
BLMD_19555	COG1021	2,3-dihydroxybenzoate-AMP ligase
BLMD_19560	COG1169	isochorismate synthase
BLMD_19565	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_19570	COG2819	hydrolase of the alpha beta superfamily
BLMD_19575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_19580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_19585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_19590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_19590	COG2207	Transcriptional regulator
BLMD_19600	COG2910	NAD(P)H-binding
BLMD_19605	COG1959	2 iron, 2 sulfur cluster binding
BLMD_19615	COG1994	Peptidase M50
BLMD_19620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BLMD_19625	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BLMD_19635	COG3383	formate dehydrogenase (NAD+) activity
BLMD_19640	COG2304	oxidoreductase activity
BLMD_19645	COG2304	oxidoreductase activity
BLMD_19650	COG2385	sporulation resulting in formation of a cellular spore
BLMD_19655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLMD_19665	COG4836	Membrane
BLMD_19670	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BLMD_19675	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BLMD_19680	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BLMD_19685	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BLMD_19690	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLMD_19695	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BLMD_19700	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLMD_19705	COG0356	it plays a direct role in the translocation of protons across the membrane
BLMD_19720	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BLMD_19725	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BLMD_19730	COG4475	Protein of unknown function (DUF436)
BLMD_19735	COG0698	ribose 5-phosphate isomerase
BLMD_19740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLMD_19745	COG1971	Probably functions as a manganese efflux pump
BLMD_19750	COG0009	L-threonylcarbamoyladenylate synthase
BLMD_19755	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BLMD_19765	COG0738	Major facilitator superfamily
BLMD_19770	COG0673	inositol 2-dehydrogenase activity
BLMD_19775	COG0561	phosphatase activity
BLMD_19780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BLMD_19785	COG1609	Transcriptional regulator
BLMD_19795	COG2890	protein-(glutamine-N5) methyltransferase activity
BLMD_19800	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BLMD_19805	COG0346	lactoylglutathione lyase activity
BLMD_19810	COG0789	Transcriptional regulator
BLMD_19815	COG0679	Auxin Efflux Carrier
BLMD_19820	COG0281	malic enzyme
BLMD_19825	COG1435	thymidine kinase activity
BLMD_19830	COG0254	rRNA binding
BLMD_19835	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BLMD_19840	COG1494	fructose-1,6-bisphosphatase
BLMD_19845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLMD_19850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BLMD_19855	COG0191	fructose-bisphosphate aldolase activity
BLMD_19860	COG2204	response regulator
BLMD_19865	COG4821	SIS domain
BLMD_19870	COG0504	CTP synthase activity
BLMD_19875	COG3343	RNA polymerase activity
BLMD_19880	COG1960	acyl-CoA dehydrogenase activity
BLMD_19885	COG1960	acyl-CoA dehydrogenase activity
BLMD_19890	COG1250	3-hydroxyacyl-CoA dehydrogenase
BLMD_19895	COG0183	Belongs to the thiolase family
BLMD_19900	COG2181	nitrate reductase activity
BLMD_19900	COG0247	lactate metabolic process
BLMD_19905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLMD_19915	COG0018	arginyl-trna synthetase
BLMD_19920	COG4506	Protein conserved in bacteria
BLMD_19925	COG0010	Belongs to the arginase family
BLMD_19930	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BLMD_19935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLMD_19945	COG1994	Peptidase M50
BLMD_19950	COG1942	4-Oxalocrotonate Tautomerase
BLMD_19960	COG3465	dGTPase activity
BLMD_19965	COG1078	dGTPase activity
BLMD_19970	COG4844	belongs to the
BLMD_19995	COG2814	Major facilitator Superfamily
BLMD_20020	COG1414	Transcriptional regulator
BLMD_20030	COG0280	phosphate acetyltransferase
BLMD_20050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLMD_20070	COG1131	(ABC) transporter
BLMD_20085	COG2363	Small membrane protein
BLMD_20090	COG2233	PERMEase
BLMD_20100	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_20105	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BLMD_20110	COG1216	Glycosyl transferase, family 2
BLMD_20115	COG0351	phosphomethylpyrimidine kinase
BLMD_20125	COG1621	beta-fructofuranosidase activity
BLMD_20130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_20130	COG1263	PTS System
BLMD_20135	COG3711	transcriptional antiterminator
BLMD_20145	COG1404	Belongs to the peptidase S8 family
BLMD_20155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLMD_20160	COG0778	Nitroreductase
BLMD_20165	COG1473	amidohydrolase
BLMD_20170	COG0772	Belongs to the SEDS family
BLMD_20175	COG0772	Belongs to the SEDS family
BLMD_20195	COG0456	acetyltransferase
BLMD_20235	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BLMD_20245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BLMD_20250	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BLMD_20255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLMD_20270	COG0655	NAD(P)H dehydrogenase (quinone) activity
BLMD_20275	COG3162	membrane
BLMD_20280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLMD_20285	COG1070	Carbohydrate kinase
BLMD_20290	COG2115	Belongs to the xylose isomerase family
BLMD_20295	COG1940	carbohydrate kinase activity
BLMD_20300	COG0352	thiamine-phosphate diphosphorylase activity
BLMD_20305	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BLMD_20310	COG0583	DNA-binding transcription factor activity
BLMD_20325	COG1380	Effector of murein hydrolase LrgA
BLMD_20330	COG1346	cytolysis
BLMD_20340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLMD_20345	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BLMD_20350	COG0346	lactoylglutathione lyase activity
BLMD_20355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLMD_20360	COG1442	glycosyl transferase family 8
BLMD_20365	COG4585	Histidine kinase
BLMD_20370	COG2197	response regulator
BLMD_20375	COG2409	Drug exporters of the RND superfamily
BLMD_20380	COG5522	Integral membrane protein (intg_mem_TP0381)
BLMD_20385	COG2271	Major facilitator Superfamily
BLMD_20390	COG4948	Mandelate Racemase Muconate Lactonizing
BLMD_20395	COG0800	Aldolase
BLMD_20400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLMD_20410	COG2234	aminopeptidase activity
BLMD_20415	COG0477	Major facilitator Superfamily
BLMD_20430	COG2357	RelA SpoT domain protein
BLMD_20445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_20450	COG1696	Membrane protein involved in D-alanine export
BLMD_20455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLMD_20460	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BLMD_20465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLMD_20470	COG2814	Major facilitator Superfamily
BLMD_20475	COG1486	melibiose metabolic process
BLMD_20480	COG1447	Phosphotransferase system cellobiose-specific component IIA
BLMD_20485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_20490	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_20495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_20495	COG3711	transcriptional antiterminator
BLMD_20500	COG2094	Belongs to the DNA glycosylase MPG family
BLMD_20510	COG0372	Belongs to the citrate synthase family
BLMD_20515	COG2079	MmgE PrpD family protein
BLMD_20520	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BLMD_20535	COG1132	(ABC) transporter
BLMD_20540	COG2755	lipolytic protein G-D-S-L family
BLMD_20555	COG2814	Major facilitator Superfamily
BLMD_20560	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BLMD_20565	COG1131	(ABC) transporter
BLMD_20585	COG1595	DNA-templated transcription, initiation
BLMD_20590	COG2814	Major facilitator Superfamily
BLMD_20600	COG0753	catalase activity
BLMD_20605	COG0753	catalase activity
BLMD_20610	COG0735	belongs to the Fur family
BLMD_20620	COG3866	Pectate lyase
BLMD_20625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BLMD_20630	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BLMD_20635	COG4988	ABC transporter
BLMD_20640	COG1294	oxidase, subunit
BLMD_20645	COG1271	oxidase subunit
BLMD_20655	COG2116	formate transmembrane transporter activity
BLMD_20665	COG0281	malic enzyme
BLMD_20670	COG1757	Na H antiporter
BLMD_20675	COG1027	Aspartate ammonia-lyase
BLMD_20680	COG0252	asparaginase activity
BLMD_20685	COG1396	sequence-specific DNA binding
BLMD_20690	COG2706	6-phosphogluconolactonase activity
BLMD_20695	COG0745	RESPONSE REGULATOR receiver
BLMD_20700	COG2205	protein histidine kinase activity
BLMD_20705	COG1136	(ABC) transporter
BLMD_20710	COG0577	efflux transmembrane transporter activity
BLMD_20715	COG5294	Protein conserved in bacteria
BLMD_20730	COG0726	polysaccharide deacetylase
BLMD_20735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_20745	COG1215	transferase activity, transferring glycosyl groups
BLMD_20750	COG3493	citrate carrier protein
BLMD_20755	COG0584	glycerophosphoryl diester phosphodiesterase
BLMD_20770	COG1368	sulfuric ester hydrolase activity
BLMD_20780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_20795	COG2235	arginine
BLMD_20800	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BLMD_20810	COG0549	Belongs to the carbamate kinase family
BLMD_20820	COG2723	6-phospho-beta-galactosidase activity
BLMD_20825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_20835	COG1595	DNA-templated transcription, initiation
BLMD_20845	COG2195	Cleaves the N-terminal amino acid of tripeptides
BLMD_20855	COG2223	nitrite transmembrane transporter activity
BLMD_20860	COG0395	ABC-type sugar transport system, permease component
BLMD_20865	COG1175	transmembrane transport
BLMD_20875	COG1609	Transcriptional regulator
BLMD_20890	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BLMD_20895	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BLMD_20900	COG0463	Glycosyl transferase, family 2
BLMD_20905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLMD_20935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BLMD_20945	COG0753	catalase activity
BLMD_20945	COG0693	protein deglycase activity
BLMD_20955	COG2723	6-phospho-beta-galactosidase activity
BLMD_20960	COG2190	(PTS) system
BLMD_20960	COG1263	PTS System
BLMD_20960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_20965	COG3711	transcriptional antiterminator
BLMD_20970	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BLMD_20975	COG1122	ATPase activity
BLMD_20980	COG4721	ABC-type cobalt transport system, permease component
BLMD_20985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BLMD_20990	COG2224	Isocitrate lyase
BLMD_20995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BLMD_21005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BLMD_21010	COG0577	efflux transmembrane transporter activity
BLMD_21015	COG1136	(ABC) transporter
BLMD_21020	COG2205	protein histidine kinase activity
BLMD_21025	COG0745	RESPONSE REGULATOR receiver
BLMD_21030	COG2723	6-phospho-beta-galactosidase activity
BLMD_21035	COG1263	PTS System
BLMD_21035	COG2190	(PTS) system
BLMD_21035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_21045	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BLMD_21050	COG3507	Belongs to the glycosyl hydrolase 43 family
BLMD_21055	COG0513	Belongs to the DEAD box helicase family
BLMD_21100	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BLMD_21105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BLMD_21110	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BLMD_21115	COG2390	Transcriptional regulator
BLMD_21120	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BLMD_21125	COG3706	GGDEF domain
BLMD_21130	COG5298	Protein conserved in bacteria
BLMD_21135	COG1215	transferase activity, transferring glycosyl groups
BLMD_21145	COG3977	Valine--pyruvate aminotransferase
BLMD_21160	COG1181	Belongs to the D-alanine--D-alanine ligase family
BLMD_21170	COG0191	fructose-bisphosphate aldolase activity
BLMD_21175	COG1082	Xylose isomerase domain protein TIM barrel
BLMD_21180	COG1082	Xylose isomerase domain protein TIM barrel
BLMD_21185	COG0673	inositol 2-dehydrogenase activity
BLMD_21190	COG2814	Major facilitator Superfamily
BLMD_21195	COG1082	Xylose isomerase domain protein TIM barrel
BLMD_21200	COG3962	Belongs to the TPP enzyme family
BLMD_21205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLMD_21210	COG3718	enzyme involved in inositol metabolism
BLMD_21215	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_21220	COG1349	DNA-binding transcription factor activity
BLMD_21225	COG0667	Aldo Keto reductase
BLMD_21230	COG0584	glycerophosphoryl diester phosphodiesterase
BLMD_21235	COG2271	Major facilitator Superfamily
BLMD_21240	COG0326	Molecular chaperone. Has ATPase activity
BLMD_21245	COG0488	(ABC) transporter
BLMD_21250	COG0561	phosphatase activity
BLMD_21270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_21300	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BLMD_21305	COG0577	efflux transmembrane transporter activity
BLMD_21310	COG1136	(ABC) transporter
BLMD_21315	COG2205	protein histidine kinase activity
BLMD_21320	COG0745	RESPONSE REGULATOR receiver
BLMD_21330	COG5278	phosphoserine phosphatase activity
BLMD_21330	COG0840	transmembrane signaling receptor activity
BLMD_21335	COG1115	amino acid carrier protein
BLMD_21340	COG0686	Belongs to the AlaDH PNT family
BLMD_21345	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BLMD_21350	COG1874	Beta-galactosidase
BLMD_21355	COG3833	ABC-type maltose transport systems, permease component
BLMD_21360	COG1175	transmembrane transport
BLMD_21365	COG2182	Extracellular solute-binding protein
BLMD_21370	COG1609	Transcriptional regulator
BLMD_21375	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BLMD_21380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLMD_21385	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BLMD_21390	COG1940	carbohydrate kinase activity
BLMD_21400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLMD_21430	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_21430	COG1454	alcohol dehydrogenase
BLMD_21435	COG0450	alkyl hydroperoxide reductase
BLMD_21440	COG3634	alkyl hydroperoxide reductase activity
BLMD_21445	COG1113	amino acid transport
BLMD_21465	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BLMD_21475	COG2205	protein histidine kinase activity
BLMD_21485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_21490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_21495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_21510	COG1131	(ABC) transporter
BLMD_21515	COG0842	Transport permease protein
BLMD_21520	COG4585	Histidine kinase
BLMD_21525	COG2197	response regulator
BLMD_21530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BLMD_21540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BLMD_21555	COG0456	acetyltransferase
BLMD_21570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLMD_21575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BLMD_21580	COG4853	Protein conserved in bacteria
BLMD_21585	COG4863	YycH protein
BLMD_21590	COG5002	protein histidine kinase activity
BLMD_21595	COG0745	RESPONSE REGULATOR receiver
BLMD_21625	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BLMD_21635	COG0305	Participates in initiation and elongation during chromosome replication
BLMD_21650	COG3093	addiction module antidote protein HigA
BLMD_21655	COG2807	transmembrane transport
BLMD_21660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BLMD_21665	COG0363	glucosamine-6-phosphate deaminase activity
BLMD_21675	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BLMD_21680	COG1263	PTS System
BLMD_21680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_21685	COG0359	binds to the 23S rRNA
BLMD_21690	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BLMD_21695	COG4241	membrane
BLMD_21700	COG5577	PFAM Coat F domain
BLMD_21705	COG0589	response to stress
BLMD_21710	COG0659	secondary active sulfate transmembrane transporter activity
BLMD_21715	COG2271	Major facilitator Superfamily
BLMD_21720	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BLMD_21725	COG0629	single-stranded DNA binding
BLMD_21730	COG0360	Binds together with S18 to 16S ribosomal RNA
BLMD_21735	COG0012	GTP binding
BLMD_21745	COG4481	Protein conserved in bacteria
BLMD_21750	COG3949	Membrane
BLMD_21760	COG1475	DNA binding
BLMD_21765	COG1192	Involved in chromosome partitioning
BLMD_21770	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BLMD_21775	COG1595	DNA-templated transcription, initiation
BLMD_21780	COG1475	DNA binding
BLMD_21785	COG0357	Ribosomal RNA small subunit methyltransferase G
BLMD_21790	COG0445	tRNA wobble uridine modification
BLMD_21795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BLMD_21800	COG1847	R3H domain protein
BLMD_21805	COG0706	membrane insertase activity
BLMD_21810	COG0594	ribonuclease P activity
BLMD_21815	COG0230	Belongs to the bacterial ribosomal protein bL34 family