locus-tag	class	description
RSC2_00001	COG2340	Cysteine-rich secretory protein family
RSC2_00004	COG3679	Belongs to the UPF0342 family
RSC2_00005	COG4471	UPF0298 protein
RSC2_00007	COG0742	ribosomal rna small subunit methyltransferase
RSC2_00008	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RSC2_00009	COG3314	Sporulation integral membrane protein YlbJ
RSC2_00010	COG3480	Lon protease (S16) C-terminal proteolytic domain
RSC2_00011	COG1323	Belongs to the UPF0348 family
RSC2_00012	COG1399	metal-binding, possibly nucleic acid-binding protein
RSC2_00013	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RSC2_00015	COG0454	-acetyltransferase
RSC2_00016	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RSC2_00017	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
RSC2_00018	COG2001	Belongs to the MraZ family
RSC2_00019	COG2001	Belongs to the MraZ family
RSC2_00020	COG0275	rRNA processing
RSC2_00021	COG4839	cell division protein FtsL
RSC2_00022	COG0768	penicillin binding
RSC2_00023	COG0768	penicillin binding
RSC2_00024	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RSC2_00025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RSC2_00026	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RSC2_00027	COG0772	Belongs to the SEDS family
RSC2_00028	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RSC2_00029	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RSC2_00030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RSC2_00031	COG3879	Bacterial protein of unknown function (DUF881)
RSC2_00032	COG3879	Bacterial protein of unknown function (DUF881)
RSC2_00033	COG3856	small basic protein
RSC2_00034	COG0849	cell division
RSC2_00035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RSC2_00036	COG1404	Belongs to the peptidase S8 family
RSC2_00036	COG4412	M6 family metalloprotease domain protein
RSC2_00037	COG4412	M6 family metalloprotease domain protein
RSC2_00037	COG1404	Belongs to the peptidase S8 family
RSC2_00039	COG1191	sigma factor activity
RSC2_00040	COG1191	sigma factor activity
RSC2_00041	COG1119	ATPase activity
RSC2_00042	COG0500	methyltransferase
RSC2_00043	COG1873	PFAM PRC-barrel domain
RSC2_00044	COG1496	oxidoreductase activity
RSC2_00045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RSC2_00046	COG1799	cell septum assembly
RSC2_00047	COG0762	integral membrane protein
RSC2_00048	COG2302	S4 RNA-binding domain
RSC2_00049	COG3599	regulation of cell shape
RSC2_00050	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RSC2_00051	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RSC2_00052	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RSC2_00053	COG0564	pseudouridine synthase activity
RSC2_00055	COG2233	PERMEase
RSC2_00056	COG0540	Belongs to the ATCase OTCase family
RSC2_00057	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RSC2_00058	COG0505	Belongs to the CarA family
RSC2_00059	COG0505	Belongs to the CarA family
RSC2_00060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RSC2_00061	COG0543	2 iron, 2 sulfur cluster binding
RSC2_00062	COG0167	dihydroorotate dehydrogenase activity
RSC2_00063	COG0284	orotidine-5'-phosphate decarboxylase activity
RSC2_00064	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RSC2_00066	COG0175	sulfate reduction
RSC2_00067	COG0306	phosphate transporter
RSC2_00068	COG2046	Belongs to the sulfate adenylyltransferase family
RSC2_00069	COG0529	Catalyzes the synthesis of activated sulfate
RSC2_00070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RSC2_00071	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
RSC2_00072	COG1648	precorrin-2 dehydrogenase activity
RSC2_00074	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RSC2_00075	COG1561	YicC-like family, N-terminal region
RSC2_00076	COG2052	Domain of unknown function (DUF370)
RSC2_00077	COG0194	GDP metabolic process
RSC2_00078	COG1758	RNA polymerase activity
RSC2_00079	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RSC2_00080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RSC2_00081	COG0242	peptide deformylase activity
RSC2_00082	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RSC2_00083	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RSC2_00083	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RSC2_00084	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RSC2_00085	COG0631	protein serine/threonine phosphatase activity
RSC2_00086	COG0515	serine threonine protein kinase
RSC2_00086	COG2815	serine threonine protein kinase
RSC2_00087	COG1162	GTPase activity
RSC2_00088	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RSC2_00089	COG1564	THIamine pyrophosphokinase
RSC2_00090	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RSC2_00091	COG1302	Protein conserved in bacteria
RSC2_00092	COG1461	Dihydroxyacetone kinase
RSC2_00093	COG1760	l-serine dehydratase
RSC2_00094	COG1760	l-serine dehydratase
RSC2_00095	COG1760	l-serine dehydratase
RSC2_00096	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RSC2_00097	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RSC2_00098	COG1349	DNA-binding transcription factor activity
RSC2_00099	COG0416	fatty acid biosynthetic process
RSC2_00100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RSC2_00101	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_00102	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RSC2_00103	COG0571	ribonuclease III activity
RSC2_00104	COG1196	nuclear chromosome segregation
RSC2_00105	COG0552	protein localization to endoplasmic reticulum
RSC2_00106	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
RSC2_00107	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RSC2_00108	COG0228	four-way junction DNA binding
RSC2_00109	COG1837	Belongs to the UPF0109 family
RSC2_00111	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RSC2_00112	COG0336	Belongs to the RNA methyltransferase TrmD family
RSC2_00113	COG0335	large ribosomal subunit rRNA binding
RSC2_00114	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RSC2_00115	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RSC2_00117	COG2257	FlhB HrpN YscU SpaS Family
RSC2_00118	COG0045	succinate-CoA ligase (ADP-forming) activity
RSC2_00119	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RSC2_00122	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RSC2_00123	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
RSC2_00124	COG4974	Belongs to the 'phage' integrase family
RSC2_00125	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RSC2_00126	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RSC2_00127	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RSC2_00129	COG1815	bacterial-type flagellum-dependent cell motility
RSC2_00130	COG1558	bacterial-type flagellum-dependent cell motility
RSC2_00131	COG1677	Flagellar hook-basal body complex protein FliE
RSC2_00132	COG1766	The M ring may be actively involved in energy transduction
RSC2_00133	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RSC2_00134	COG1317	bacterial-type flagellum organization
RSC2_00135	COG1157	protein secretion by the type III secretion system
RSC2_00136	COG2882	bacterial-type flagellum organization
RSC2_00138	COG3144	bacterial-type flagellum assembly
RSC2_00139	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RSC2_00140	COG4786	Flagellar basal body rod
RSC2_00141	COG1582	Flagellar protein (FlbD)
RSC2_00142	COG1580	Controls the rotational direction of flagella during chemotaxis
RSC2_00143	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RSC2_00144	COG1776	CheC inhibitor of MCP methylation
RSC2_00144	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RSC2_00145	COG2201	protein-glutamate methylesterase activity
RSC2_00146	COG3190	flagellar
RSC2_00147	COG1338	Plays a role in the flagellum-specific transport system
RSC2_00148	COG1987	bacterial-type flagellum assembly
RSC2_00149	COG1684	flagellar biosynthetic protein fliR
RSC2_00150	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RSC2_00151	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RSC2_00152	COG1419	protein localization to endoplasmic reticulum
RSC2_00153	COG0455	bacterial-type flagellum organization
RSC2_00154	COG2201	protein-glutamate methylesterase activity
RSC2_00155	COG0643	Histidine kinase
RSC2_00155	COG2198	Histidine kinase
RSC2_00156	COG0835	chemotaxis
RSC2_00157	COG1776	CheC inhibitor of MCP methylation
RSC2_00158	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RSC2_00159	COG1191	sigma factor activity
RSC2_00161	COG0052	Belongs to the universal ribosomal protein uS2 family
RSC2_00162	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RSC2_00163	COG0528	UMP kinase activity
RSC2_00164	COG0233	cytoplasmic translational termination
RSC2_00165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RSC2_00166	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RSC2_00167	COG4589	Belongs to the CDS family
RSC2_00168	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RSC2_00169	COG0750	zinc metalloprotease
RSC2_00170	COG0442	prolyl-tRNA aminoacylation
RSC2_00171	COG2176	DNA-directed DNA polymerase activity
RSC2_00177	COG0779	Required for maturation of 30S ribosomal subunits
RSC2_00178	COG0195	Participates in both transcription termination and antitermination
RSC2_00179	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RSC2_00180	COG1358	cellular component organization or biogenesis
RSC2_00181	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RSC2_00182	COG1550	Protein conserved in bacteria
RSC2_00183	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RSC2_00184	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RSC2_00185	COG0196	riboflavin kinase activity
RSC2_00186	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RSC2_00187	COG1185	polyribonucleotide nucleotidyltransferase activity
RSC2_00188	COG0726	polysaccharide deacetylase
RSC2_00189	COG0612	Peptidase, M16
RSC2_00190	COG1873	PFAM PRC-barrel domain
RSC2_00191	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RSC2_00192	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RSC2_00193	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RSC2_00194	COG0527	aspartate kinase activity
RSC2_00196	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RSC2_00197	COG0740	serine-type endopeptidase activity
RSC2_00199	COG1674	ftsk spoiiie
RSC2_00199	COG4980	gas vesicle protein
RSC2_00200	COG2188	Transcriptional regulator
RSC2_00201	COG2814	Major facilitator Superfamily
RSC2_00202	COG0612	Peptidase, M16
RSC2_00203	COG0612	Peptidase, M16
RSC2_00204	COG0300	oxidoreductase activity
RSC2_00207	COG1426	Protein conserved in bacteria
RSC2_00208	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RSC2_00209	COG1058	Belongs to the CinA family
RSC2_00209	COG1546	Belongs to the CinA family
RSC2_00211	COG1418	mRNA catabolic process
RSC2_00212	COG1692	metallophosphoesterase
RSC2_00213	COG2359	stage V sporulation protein S
RSC2_00214	COG1063	alcohol dehydrogenase
RSC2_00216	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RSC2_00217	COG4550	Control of competence regulator ComK, YlbF/YmcA
RSC2_00219	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RSC2_00220	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RSC2_00221	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RSC2_00224	COG0457	Tetratricopeptide repeat
RSC2_00226	COG5444	nuclease activity
RSC2_00228	COG3677	Transposase
RSC2_00230	COG5484	DNA packaging
RSC2_00231	COG5484	DNA packaging
RSC2_00232	COG5484	DNA packaging
RSC2_00233	COG1783	phage Terminase large subunit
RSC2_00234	COG1783	phage Terminase large subunit
RSC2_00236	COG1783	phage Terminase large subunit
RSC2_00237	COG5518	Phage portal protein
RSC2_00238	COG2369	cell adhesion
RSC2_00240	COG0338	D12 class N6 adenine-specific DNA methyltransferase
RSC2_00241	COG4653	Phage capsid family
RSC2_00246	COG5444	nuclease activity
RSC2_00247	COG5444	nuclease activity
RSC2_00251	COG0523	cobalamin synthesis protein
RSC2_00255	COG1231	oxidoreductase activity
RSC2_00256	COG1231	oxidoreductase activity
RSC2_00257	COG3619	membrane
RSC2_00258	COG3263	regulation of cellular component size
RSC2_00259	COG2814	Major facilitator Superfamily
RSC2_00261	COG0393	Putative heavy-metal-binding
RSC2_00262	COG0398	Pfam SNARE associated Golgi protein
RSC2_00263	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RSC2_00264	COG1819	glycosyl
RSC2_00265	COG0531	amino acid
RSC2_00266	COG5577	PFAM Coat F domain
RSC2_00268	COG3858	chitin binding
RSC2_00268	COG1388	LysM domain
RSC2_00269	COG1309	transcriptional regulator
RSC2_00270	COG3631	Ketosteroid isomerase-related protein
RSC2_00271	COG0702	epimerase
RSC2_00272	COG0702	epimerase
RSC2_00274	COG1764	response to oxidative stress
RSC2_00275	COG2076	Multidrug Resistance protein
RSC2_00276	COG2076	Multidrug Resistance protein
RSC2_00279	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RSC2_00280	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RSC2_00281	COG1923	regulation of RNA biosynthetic process
RSC2_00283	COG1780	Probably involved in ribonucleotide reductase function
RSC2_00284	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RSC2_00285	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RSC2_00286	COG4112	unkown
RSC2_00289	COG0735	belongs to the Fur family
RSC2_00290	COG1802	Transcriptional regulator
RSC2_00291	COG0697	spore germination
RSC2_00297	COG1309	transcriptional regulator
RSC2_00304	COG4282	regulation of fungal-type cell wall biogenesis
RSC2_00305	COG5444	nuclease activity
RSC2_00311	COG2814	Major facilitator Superfamily
RSC2_00312	COG0457	Tetratricopeptide repeat
RSC2_00315	COG4413	Urea transporter
RSC2_00317	COG0831	urea catabolic process
RSC2_00318	COG0832	Belongs to the urease beta subunit family
RSC2_00320	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
RSC2_00322	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RSC2_00323	COG0829	nickel cation binding
RSC2_00325	COG1695	Transcriptional regulator
RSC2_00330	COG0464	growth
RSC2_00331	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RSC2_00332	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RSC2_00333	COG0789	Transcriptional regulator
RSC2_00334	COG0174	glutamine synthetase
RSC2_00340	COG0174	glutamine synthetase
RSC2_00349	COG0490	domain, Protein
RSC2_00350	COG0475	glutathione-regulated potassium exporter activity
RSC2_00352	COG1073	alpha beta
RSC2_00362	COG1309	transcriptional regulator
RSC2_00363	COG2076	Multidrug Resistance protein
RSC2_00364	COG2076	Multidrug Resistance protein
RSC2_00365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RSC2_00368	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC2_00369	COG3546	catalase activity
RSC2_00375	COG1846	Transcriptional regulator
RSC2_00376	COG0346	lactoylglutathione lyase activity
RSC2_00377	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RSC2_00378	COG0655	NAD(P)H dehydrogenase (quinone) activity
RSC2_00383	COG3209	COG3209 Rhs family protein
RSC2_00384	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RSC2_00385	COG1388	LysM domain
RSC2_00386	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RSC2_00387	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RSC2_00388	COG4224	UPF0291 protein
RSC2_00389	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RSC2_00391	COG3763	UPF0154 protein
RSC2_00393	COG0785	Cytochrome C biogenesis protein
RSC2_00394	COG2201	protein-glutamate methylesterase activity
RSC2_00395	COG4846	Membrane protein involved in cytochrome C biogenesis
RSC2_00397	COG0071	Belongs to the small heat shock protein (HSP20) family
RSC2_00400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RSC2_00401	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC2_00405	COG0824	Thioesterase
RSC2_00410	COG4841	protein insertion into membrane
RSC2_00411	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RSC2_00412	COG1832	CoA-binding protein
RSC2_00413	COG0187	DNA topoisomerase II activity
RSC2_00414	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RSC2_00416	COG1609	Transcriptional regulator
RSC2_00419	COG2160	L-arabinose isomerase activity
RSC2_00425	COG1115	amino acid carrier protein
RSC2_00427	COG2181	nitrate reductase activity
RSC2_00428	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RSC2_00429	COG1140	nitrate reductase beta subunit
RSC2_00430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RSC2_00433	COG0535	radical SAM domain protein
RSC2_00434	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RSC2_00436	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RSC2_00437	COG2223	nitrite transmembrane transporter activity
RSC2_00441	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
RSC2_00443	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RSC2_00445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RSC2_00449	COG0477	Major facilitator Superfamily
RSC2_00450	COG3420	alginic acid biosynthetic process
RSC2_00451	COG1114	Component of the transport system for branched-chain amino acids
RSC2_00453	COG1687	branched-chain amino acid
RSC2_00454	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RSC2_00455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC2_00456	COG1064	alcohol dehydrogenase
RSC2_00460	COG1024	Enoyl-CoA hydratase
RSC2_00461	COG1012	belongs to the aldehyde dehydrogenase family
RSC2_00462	COG2084	Dehydrogenase
RSC2_00463	COG1960	acyl-CoA dehydrogenase activity
RSC2_00464	COG1482	cell wall glycoprotein biosynthetic process
RSC2_00465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSC2_00465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSC2_00465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC2_00468	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC2_00468	COG3711	transcriptional antiterminator
RSC2_00471	COG1725	Transcriptional regulator
RSC2_00472	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_00473	COG1312	Catalyzes the dehydration of D-mannonate
RSC2_00476	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RSC2_00478	COG1609	Transcriptional regulator
RSC2_00479	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RSC2_00480	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RSC2_00481	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
RSC2_00484	COG1649	PFAM Uncharacterised BCR, COG1649
RSC2_00485	COG2404	hydrolase activity, acting on ester bonds
RSC2_00486	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RSC2_00488	COG0438	transferase activity, transferring glycosyl groups
RSC2_00489	COG2027	D-alanyl-D-alanine carboxypeptidase
RSC2_00493	COG1309	transcriptional regulator
RSC2_00494	COG1252	NADH dehydrogenase
RSC2_00497	COG0166	Belongs to the GPI family
RSC2_00499	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RSC2_00500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RSC2_00501	COG1024	Enoyl-CoA hydratase
RSC2_00502	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RSC2_00503	COG0511	ligase activity, forming carbon-carbon bonds
RSC2_00504	COG0439	Biotin carboxylase
RSC2_00505	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RSC2_00505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC2_00506	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC2_00507	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC2_00508	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC2_00509	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC2_00510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC2_00511	COG0318	PFAM AMP-dependent synthetase and ligase
RSC2_00512	COG1960	acyl-CoA dehydrogenase activity
RSC2_00513	COG2249	NAD(P)H dehydrogenase (quinone) activity
RSC2_00514	COG1733	regulation of RNA biosynthetic process
RSC2_00515	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RSC2_00516	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RSC2_00518	COG2323	membrane
RSC2_00519	COG0306	phosphate transporter
RSC2_00520	COG0175	sulfate reduction
RSC2_00521	COG1809	phosphosulfolactate synthase activity
RSC2_00522	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC2_00523	COG4948	Mandelate Racemase Muconate Lactonizing
RSC2_00524	COG2814	Major facilitator Superfamily
RSC2_00525	COG0463	Glycosyl transferase, family 2
RSC2_00528	COG0493	'glutamate synthase
RSC2_00529	COG0070	glutamate synthase
RSC2_00529	COG0069	glutamate synthase activity
RSC2_00529	COG0067	glutamate synthase
RSC2_00530	COG0583	DNA-binding transcription factor activity
RSC2_00535	COG1132	(ABC) transporter
RSC2_00537	COG0300	oxidoreductase activity
RSC2_00538	COG0574	Belongs to the PEP-utilizing enzyme family
RSC2_00538	COG3848	Pyruvate phosphate dikinase
RSC2_00539	COG0477	Major facilitator Superfamily
RSC2_00540	COG0243	molybdopterin cofactor binding
RSC2_00541	COG1846	Transcriptional regulator
RSC2_00542	COG2814	Major facilitator Superfamily
RSC2_00543	COG0531	amino acid
RSC2_00544	COG0531	amino acid
RSC2_00546	COG0531	amino acid
RSC2_00547	COG0531	amino acid
RSC2_00548	COG0531	amino acid
RSC2_00549	COG0697	spore germination
RSC2_00551	COG0488	(ABC) transporter
RSC2_00552	COG0840	transmembrane signaling receptor activity
RSC2_00553	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RSC2_00555	COG1404	Belongs to the peptidase S8 family
RSC2_00557	COG1309	transcriptional regulator
RSC2_00558	COG1846	Transcriptional regulator
RSC2_00564	COG1309	transcriptional regulator
RSC2_00565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC2_00566	COG3708	Transcriptional regulator
RSC2_00568	COG2378	regulation of single-species biofilm formation
RSC2_00570	COG0640	Transcriptional regulator
RSC2_00571	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC2_00573	COG0531	amino acid
RSC2_00574	COG0741	lytic transglycosylase activity
RSC2_00575	COG1086	Polysaccharide biosynthesis protein
RSC2_00578	COG0438	transferase activity, transferring glycosyl groups
RSC2_00579	COG2322	membrane
RSC2_00582	COG1619	proteins homologs of microcin C7 resistance protein MccF
RSC2_00583	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC2_00584	COG3584	3D domain protein
RSC2_00584	COG1388	LysM domain
RSC2_00585	COG0514	ATP-dependent DNA helicase (RecQ)
RSC2_00589	COG2315	Protein conserved in bacteria
RSC2_00590	COG2427	Protein of unknown function (DUF1641)
RSC2_00591	COG3383	formate dehydrogenase (NAD+) activity
RSC2_00593	COG5444	nuclease activity
RSC2_00597	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
RSC2_00605	COG2350	Protein conserved in bacteria
RSC2_00610	COG0402	S-adenosylhomocysteine deaminase activity
RSC2_00613	COG2267	carboxylic ester hydrolase activity
RSC2_00616	COG1280	lysine exporter protein (LysE YggA)
RSC2_00617	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RSC2_00619	COG0574	Belongs to the PEP-utilizing enzyme family
RSC2_00619	COG3848	Pyruvate phosphate dikinase
RSC2_00620	COG0574	Belongs to the PEP-utilizing enzyme family
RSC2_00620	COG3848	Pyruvate phosphate dikinase
RSC2_00624	COG2318	DinB family
RSC2_00625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RSC2_00629	COG0156	8-amino-7-oxononanoate synthase activity
RSC2_00630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RSC2_00632	COG1012	belongs to the aldehyde dehydrogenase family
RSC2_00633	COG2814	Major facilitator Superfamily
RSC2_00636	COG1657	PFAM Prenyltransferase squalene oxidase
RSC2_00637	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RSC2_00639	COG0733	neurotransmitter:sodium symporter activity
RSC2_00640	COG0385	Bile acid
RSC2_00641	COG0508	dehydrogenase complex catalyzes the overall conversion of
RSC2_00642	COG0567	Dehydrogenase, E1 component
RSC2_00643	COG4548	von Willebrand factor, type A
RSC2_00644	COG0714	Associated with various cellular activities
RSC2_00645	COG2032	superoxide dismutase activity
RSC2_00646	COG0791	NLP P60 protein
RSC2_00646	COG1388	LysM domain
RSC2_00648	COG0534	Mate efflux family protein
RSC2_00649	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RSC2_00650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RSC2_00652	COG2962	Rard protein
RSC2_00654	COG4305	rare lipoprotein A
RSC2_00656	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_00657	COG1733	regulation of RNA biosynthetic process
RSC2_00658	COG0778	Nitroreductase
RSC2_00659	COG0400	carboxylic ester hydrolase activity
RSC2_00661	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC2_00662	COG0793	Belongs to the peptidase S41A family
RSC2_00662	COG3409	Peptidoglycan-binding domain 1 protein
RSC2_00663	COG2226	methyltransferase
RSC2_00665	COG1876	peptidase activity
RSC2_00666	COG0813	purine-nucleoside phosphorylase activity
RSC2_00667	COG0701	Predicted permease
RSC2_00671	COG0671	phosphoesterase, PA-phosphatase related
RSC2_00675	COG4479	Belongs to the UPF0346 family
RSC2_00677	COG1509	lysine 2,3-aminomutase activity
RSC2_00678	COG0456	acetyltransferase
RSC2_00679	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RSC2_00680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RSC2_00681	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RSC2_00682	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RSC2_00685	COG0456	acetyltransferase
RSC2_00686	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RSC2_00687	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RSC2_00688	COG1846	Transcriptional regulator
RSC2_00690	COG3706	GGDEF domain
RSC2_00691	COG0534	Mate efflux family protein
RSC2_00692	COG0534	Mate efflux family protein
RSC2_00695	COG4698	Protein conserved in bacteria
RSC2_00696	COG2755	lipolytic protein G-D-S-L family
RSC2_00697	COG1999	signal sequence binding
RSC2_00700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RSC2_00702	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RSC2_00703	COG1272	protein, Hemolysin III
RSC2_00704	COG0204	Acyl-transferase
RSC2_00705	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RSC2_00706	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RSC2_00709	COG2136	Putative SAM-dependent methyltransferase
RSC2_00709	COG2521	methyltransferase
RSC2_00711	COG0129	dihydroxy-acid dehydratase activity
RSC2_00713	COG1413	lyase activity
RSC2_00714	COG1418	mRNA catabolic process
RSC2_00715	COG0386	Belongs to the glutathione peroxidase family
RSC2_00716	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RSC2_00717	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
RSC2_00718	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RSC2_00720	COG1278	Cold shock
RSC2_00724	COG0328	RNA-DNA hybrid ribonuclease activity
RSC2_00725	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RSC2_00726	COG0328	RNA-DNA hybrid ribonuclease activity
RSC2_00728	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RSC2_00731	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RSC2_00733	COG1755	Isoprenylcysteine carboxyl methyltransferase
RSC2_00734	COG3424	synthase
RSC2_00736	COG2233	PERMEase
RSC2_00737	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RSC2_00738	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
RSC2_00739	COG1199	ATP-dependent helicase activity
RSC2_00743	COG0116	Belongs to the methyltransferase superfamily
RSC2_00744	COG3599	regulation of cell shape
RSC2_00745	COG4474	Belongs to the UPF0398 family
RSC2_00748	COG3359	exonuclease
RSC2_00749	COG1205	dead DEAH box helicase
RSC2_00749	COG1111	helicase
RSC2_00750	COG2190	(PTS) system
RSC2_00751	COG0071	Belongs to the small heat shock protein (HSP20) family
RSC2_00758	COG3331	DNA recombination
RSC2_00759	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RSC2_00759	COG4499	WXG100 protein secretion system (Wss), protein YukC
RSC2_00761	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RSC2_00762	COG3935	DnaD domain protein
RSC2_00763	COG0017	Asparaginyl-tRNA synthetase
RSC2_00764	COG0436	Aminotransferase
RSC2_00765	COG5353	protein conserved in bacteria
RSC2_00767	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RSC2_00767	COG1199	ATP-dependent helicase activity
RSC2_00768	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RSC2_00769	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RSC2_00770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RSC2_00772	COG0617	tRNA 3'-terminal CCA addition
RSC2_00773	COG0438	transferase activity, transferring glycosyl groups
RSC2_00774	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RSC2_00775	COG1803	Methylglyoxal synthase
RSC2_00776	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RSC2_00777	COG1694	Mazg nucleotide pyrophosphohydrolase
RSC2_00778	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC2_00780	COG4347	Protein of unknown function (DUF1405)
RSC2_00781	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RSC2_00781	COG2010	Cytochrome c
RSC2_00782	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RSC2_00783	COG0723	plastoquinol--plastocyanin reductase activity
RSC2_00785	COG5582	Belongs to the UPF0302 family
RSC2_00786	COG0457	Tetratricopeptide repeat
RSC2_00787	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RSC2_00788	COG0287	Prephenate dehydrogenase
RSC2_00789	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RSC2_00790	COG0159	tryptophan synthase activity
RSC2_00791	COG0133	tryptophan synthase activity
RSC2_00792	COG0135	phosphoribosylanthranilate isomerase activity
RSC2_00793	COG0134	indole-3-glycerol-phosphate synthase activity
RSC2_00794	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RSC2_00795	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RSC2_00796	COG4401	Chorismate mutase type I
RSC2_00797	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RSC2_00798	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RSC2_00799	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RSC2_00800	COG0105	UTP biosynthetic process
RSC2_00801	COG0142	geranyltranstransferase activity
RSC2_00802	COG2226	methyltransferase
RSC2_00803	COG0142	geranyltranstransferase activity
RSC2_00806	COG0776	regulation of translation
RSC2_00807	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RSC2_00810	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RSC2_00811	COG1160	GTP binding
RSC2_00816	COG1304	FMN binding
RSC2_00817	COG0539	negative regulation of cytoplasmic translation
RSC2_00818	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RSC2_00820	COG2959	enzyme of heme biosynthesis
RSC2_00821	COG3409	Peptidoglycan-binding domain 1 protein
RSC2_00821	COG3773	Cell wall hydrolase
RSC2_00822	COG2339	peptidase activity
RSC2_00824	COG0492	ferredoxin-NADP+ reductase activity
RSC2_00825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RSC2_00826	COG4862	establishment of competence for transformation
RSC2_00827	COG1408	metallophosphoesterase
RSC2_00829	COG1388	LysM domain
RSC2_00830	COG1266	CAAX protease self-immunity
RSC2_00832	COG0514	ATP-dependent DNA helicase (RecQ)
RSC2_00833	COG4955	Helix-turn-helix domain
RSC2_00834	COG1141	Ferredoxin
RSC2_00835	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
RSC2_00836	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RSC2_00837	COG0739	heme binding
RSC2_00839	COG1595	DNA-templated transcription, initiation
RSC2_00840	COG1316	TRANSCRIPTIONal
RSC2_00844	COG5002	protein histidine kinase activity
RSC2_00845	COG0745	RESPONSE REGULATOR receiver
RSC2_00846	COG5002	protein histidine kinase activity
RSC2_00847	COG0745	RESPONSE REGULATOR receiver
RSC2_00848	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RSC2_00849	COG1333	cytochrome c biogenesis protein
RSC2_00850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC2_00851	COG1187	pseudouridine synthase activity
RSC2_00852	COG0700	Nucleoside recognition
RSC2_00853	COG2715	membrane protein required for spore maturation
RSC2_00854	COG1686	Belongs to the peptidase S11 family
RSC2_00856	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RSC2_00857	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RSC2_00859	COG1547	Domain of unknown function (DUF309)
RSC2_00860	COG0456	acetyltransferase
RSC2_00861	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RSC2_00862	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RSC2_00862	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RSC2_00863	COG0307	riboflavin synthase, alpha
RSC2_00864	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RSC2_00864	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RSC2_00868	COG0457	Tetratricopeptide repeat
RSC2_00869	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RSC2_00870	COG4086	secreted protein
RSC2_00871	COG4195	phage-related replication protein
RSC2_00872	COG0019	diaminopimelate decarboxylase activity
RSC2_00874	COG0697	spore germination
RSC2_00877	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RSC2_00884	COG1686	Belongs to the peptidase S11 family
RSC2_00885	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RSC2_00886	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RSC2_00887	COG4974	Belongs to the 'phage' integrase family
RSC2_00889	COG0735	belongs to the Fur family
RSC2_00890	COG1300	Membrane
RSC2_00891	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC2_00893	COG1953	Uracil, thiamine, allantoin
RSC2_00896	COG2153	protein acetylation
RSC2_00897	COG1379	DNA repair
RSC2_00898	COG0494	nUDIX hydrolase
RSC2_00900	COG1309	transcriptional regulator
RSC2_00902	COG0667	Aldo Keto reductase
RSC2_00904	COG1073	alpha beta
RSC2_00906	COG4918	Iron-sulphur cluster biosynthesis
RSC2_00908	COG0456	acetyltransferase
RSC2_00908	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RSC2_00909	COG2329	Antibiotic biosynthesis monooxygenase
RSC2_00910	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RSC2_00912	COG0747	negative chemotaxis
RSC2_00913	COG0601	transmembrane transport
RSC2_00914	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSC2_00915	COG0444	Belongs to the ABC transporter superfamily
RSC2_00918	COG0534	Mate efflux family protein
RSC2_00922	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RSC2_00924	COG2211	Major facilitator Superfamily
RSC2_00925	COG0346	lactoylglutathione lyase activity
RSC2_00926	COG1072	(Pantothenic acid kinase))
RSC2_00928	COG3842	ATPase activity
RSC2_00934	COG2205	protein histidine kinase activity
RSC2_00935	COG0745	RESPONSE REGULATOR receiver
RSC2_00940	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
RSC2_00941	COG2814	Major facilitator Superfamily
RSC2_00943	COG4195	phage-related replication protein
RSC2_00944	COG0300	oxidoreductase activity
RSC2_00945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC2_00946	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RSC2_00947	COG4187	Peptidase family M20/M25/M40
RSC2_00948	COG1902	pentaerythritol trinitrate reductase activity
RSC2_00949	COG1902	pentaerythritol trinitrate reductase activity
RSC2_00950	COG0596	Alpha beta hydrolase
RSC2_00951	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RSC2_00952	COG1234	tRNA 3'-trailer cleavage
RSC2_00953	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RSC2_00956	COG2358	TRAP transporter, solute receptor (TAXI family
RSC2_00957	COG2188	Transcriptional regulator
RSC2_00958	COG2723	6-phospho-beta-galactosidase activity
RSC2_00959	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC2_00960	COG1447	Phosphotransferase system cellobiose-specific component IIA
RSC2_00961	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC2_00962	COG1785	Belongs to the alkaline phosphatase family
RSC2_00963	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_00964	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RSC2_00965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RSC2_00967	COG0706	membrane insertase activity
RSC2_00968	COG2195	Cleaves the N-terminal amino acid of tripeptides
RSC2_00969	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RSC2_00970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RSC2_00973	COG4129	membrane
RSC2_00974	COG1126	abc transporter atp-binding protein
RSC2_00975	COG0765	amino acid transport
RSC2_00976	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RSC2_00978	COG1597	lipid kinase activity
RSC2_00980	COG0508	dehydrogenase complex catalyzes the overall conversion of
RSC2_00981	COG0022	dehydrogenase e1 component
RSC2_00982	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RSC2_00983	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RSC2_00985	COG3426	butyrate kinase activity
RSC2_00987	COG0280	phosphate acetyltransferase
RSC2_00988	COG3290	protein histidine kinase activity
RSC2_00988	COG3829	transcription factor binding
RSC2_00990	COG0584	glycerophosphoryl diester phosphodiesterase
RSC2_00991	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSC2_00996	COG0745	RESPONSE REGULATOR receiver
RSC2_00997	COG0750	zinc metalloprotease
RSC2_00998	COG0497	DNA recombination
RSC2_00999	COG1438	arginine binding
RSC2_01000	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
RSC2_01001	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RSC2_01003	COG0142	geranyltranstransferase activity
RSC2_01004	COG1722	exodeoxyribonuclease VII activity
RSC2_01005	COG1570	exodeoxyribonuclease VII activity
RSC2_01006	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RSC2_01007	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RSC2_01008	COG1302	Protein conserved in bacteria
RSC2_01009	COG0439	Biotin carboxylase
RSC2_01010	COG0511	ligase activity, forming carbon-carbon bonds
RSC2_01018	COG3854	ATPases associated with a variety of cellular activities
RSC2_01021	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RSC2_01022	COG0006	proline dipeptidase activity
RSC2_01023	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RSC2_01025	COG3872	metal-dependent enzyme
RSC2_01027	COG1752	Esterase of the alpha-beta hydrolase superfamily
RSC2_01028	COG1321	iron dependent repressor
RSC2_01029	COG0095	Lipoate-protein ligase
RSC2_01030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RSC2_01031	COG2113	Glycine betaine
RSC2_01032	COG4176	ABC-type proline glycine betaine transport system permease component
RSC2_01033	COG0517	IMP dehydrogenase activity
RSC2_01033	COG4175	Glycine betaine
RSC2_01034	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RSC2_01035	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RSC2_01036	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RSC2_01037	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RSC2_01038	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RSC2_01043	COG0681	Belongs to the peptidase S26 family
RSC2_01049	COG4940	Competence protein ComGF
RSC2_01051	COG4970	Tfp pilus assembly protein FimT
RSC2_01052	COG4537	Required for transformation and DNA binding
RSC2_01053	COG1459	type II secretion system
RSC2_01054	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RSC2_01055	COG1366	Belongs to the anti-sigma-factor antagonist family
RSC2_01056	COG1393	Belongs to the ArsC family
RSC2_01058	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC2_01060	COG0011	TIGRFAM Protein of
RSC2_01062	COG2866	Carboxypeptidase
RSC2_01064	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC2_01065	COG1368	sulfuric ester hydrolase activity
RSC2_01066	COG1940	carbohydrate kinase activity
RSC2_01067	COG4483	Protein conserved in bacteria
RSC2_01068	COG0697	spore germination
RSC2_01069	COG0457	Tetratricopeptide repeat
RSC2_01069	COG0705	Rhomboid family
RSC2_01071	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RSC2_01072	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RSC2_01073	COG0438	transferase activity, transferring glycosyl groups
RSC2_01075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RSC2_01079	COG1131	(ABC) transporter
RSC2_01084	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RSC2_01085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RSC2_01086	COG0581	inorganic phosphate transmembrane transporter activity
RSC2_01087	COG0573	inorganic phosphate transmembrane transporter activity
RSC2_01088	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RSC2_01089	COG0768	penicillin binding
RSC2_01090	COG0477	Major facilitator Superfamily
RSC2_01091	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RSC2_01092	COG2839	Protein conserved in bacteria
RSC2_01093	COG5521	maltodextrose utilization protein MalA
RSC2_01094	COG1388	LysM domain
RSC2_01095	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RSC2_01096	COG4709	membrane
RSC2_01097	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
RSC2_01098	COG0735	belongs to the Fur family
RSC2_01099	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RSC2_01100	COG1121	(ABC) transporter
RSC2_01101	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC2_01103	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
RSC2_01104	COG0513	Belongs to the DEAD box helicase family
RSC2_01106	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RSC2_01107	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RSC2_01108	COG2384	SAM-dependent methyltransferase
RSC2_01114	COG5444	nuclease activity
RSC2_01118	COG2010	Cytochrome c
RSC2_01119	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RSC2_01121	COG0358	DNA primase activity
RSC2_01122	COG1671	Belongs to the UPF0178 family
RSC2_01123	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RSC2_01124	COG0517	IMP dehydrogenase activity
RSC2_01125	COG0751	glycine-tRNA ligase activity
RSC2_01126	COG0752	glycyl-tRNA synthetase alpha subunit
RSC2_01127	COG1381	Involved in DNA repair and RecF pathway recombination
RSC2_01129	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RSC2_01130	COG0295	cytidine deaminase activity
RSC2_01131	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
RSC2_01132	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RSC2_01133	COG1480	7TM receptor with intracellular HD hydrolase
RSC2_01134	COG1702	phosphate starvation-inducible protein PhoH
RSC2_01135	COG0561	phosphatase activity
RSC2_01138	COG4864	UPF0365 protein
RSC2_01139	COG1030	water channel activity
RSC2_01140	COG1610	YqeY-like protein
RSC2_01141	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RSC2_01142	COG1283	sodium-dependent phosphate transmembrane transporter activity
RSC2_01143	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RSC2_01144	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RSC2_01145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RSC2_01146	COG2264	protein methyltransferase activity
RSC2_01147	COG0484	heat shock protein binding
RSC2_01148	COG0443	Heat shock 70 kDa protein
RSC2_01149	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RSC2_01150	COG1420	regulation of RNA biosynthetic process
RSC2_01151	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RSC2_01152	COG0481	GTPase activity
RSC2_01154	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSC2_01155	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RSC2_01156	COG0268	Binds directly to 16S ribosomal RNA
RSC2_01157	COG1733	regulation of RNA biosynthetic process
RSC2_01158	COG2249	NAD(P)H dehydrogenase (quinone) activity
RSC2_01159	COG1466	dna polymerase III delta subunit
RSC2_01161	COG0658	competence protein
RSC2_01161	COG2333	competence protein COMEC
RSC2_01162	COG2131	deaminase
RSC2_01163	COG1555	photosystem II stabilization
RSC2_01163	COG1596	polysaccharide export
RSC2_01164	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RSC2_01165	COG2226	methyltransferase
RSC2_01166	COG0799	negative regulation of ribosome biogenesis
RSC2_01167	COG1713	HD superfamily hydrolase involved in NAD metabolism
RSC2_01168	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RSC2_01169	COG1534	Rna-binding protein
RSC2_01170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RSC2_01171	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RSC2_01172	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RSC2_01174	COG2755	lipolytic protein G-D-S-L family
RSC2_01177	COG5609	conserved protein (DUF2294)
RSC2_01178	COG3383	formate dehydrogenase (NAD+) activity
RSC2_01179	COG2427	Protein of unknown function (DUF1641)
RSC2_01189	COG3223	Belongs to the PsiE family
RSC2_01190	COG0642	Histidine kinase
RSC2_01190	COG5002	protein histidine kinase activity
RSC2_01191	COG0745	RESPONSE REGULATOR receiver
RSC2_01192	COG2311	Membrane
RSC2_01193	COG0454	-acetyltransferase
RSC2_01198	COG1247	-acetyltransferase
RSC2_01200	COG0561	phosphatase activity
RSC2_01201	COG0561	phosphatase activity
RSC2_01202	COG1486	melibiose metabolic process
RSC2_01207	COG4978	Transcriptional regulator
RSC2_01207	COG0789	Transcriptional regulator
RSC2_01210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RSC2_01212	COG2828	Protein conserved in bacteria
RSC2_01214	COG2181	nitrate reductase activity
RSC2_01215	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RSC2_01216	COG1140	nitrate reductase beta subunit
RSC2_01217	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RSC2_01218	COG2223	nitrite transmembrane transporter activity
RSC2_01224	COG4585	Histidine kinase
RSC2_01225	COG0730	response to heat
RSC2_01226	COG0425	Belongs to the sulfur carrier protein TusA family
RSC2_01227	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC2_01227	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RSC2_01228	COG0425	Belongs to the sulfur carrier protein TusA family
RSC2_01228	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RSC2_01230	COG2210	Belongs to the sulfur carrier protein TusA family
RSC2_01231	COG1937	Protein conserved in bacteria
RSC2_01234	COG0113	porphobilinogen synthase activity
RSC2_01236	COG1942	4-Oxalocrotonate Tautomerase
RSC2_01237	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RSC2_01238	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RSC2_01239	COG1733	regulation of RNA biosynthetic process
RSC2_01240	COG3239	Fatty acid desaturase
RSC2_01241	COG4585	Histidine kinase
RSC2_01242	COG2197	response regulator
RSC2_01243	COG0492	ferredoxin-NADP+ reductase activity
RSC2_01245	COG0747	negative chemotaxis
RSC2_01246	COG0601	transmembrane transport
RSC2_01247	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSC2_01248	COG0444	Belongs to the ABC transporter superfamily
RSC2_01249	COG4608	Belongs to the ABC transporter superfamily
RSC2_01253	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_01255	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
RSC2_01258	COG2124	cytochrome p450
RSC2_01259	COG3507	Belongs to the glycosyl hydrolase 43 family
RSC2_01260	COG2211	Major facilitator Superfamily
RSC2_01262	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_01263	COG1621	beta-fructofuranosidase activity
RSC2_01264	COG1621	beta-fructofuranosidase activity
RSC2_01265	COG3716	PTS system mannose fructose sorbose family IID component
RSC2_01266	COG3715	PTS system
RSC2_01267	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_01268	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC2_01269	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RSC2_01269	COG3933	PFAM sigma-54 factor interaction domain-containing protein
RSC2_01274	COG2169	Transcriptional regulator
RSC2_01275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RSC2_01276	COG2205	protein histidine kinase activity
RSC2_01278	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
RSC2_01279	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RSC2_01282	COG0656	L-ascorbic acid biosynthetic process
RSC2_01283	COG2814	Major facilitator Superfamily
RSC2_01284	COG1733	regulation of RNA biosynthetic process
RSC2_01285	COG3340	Belongs to the peptidase S51 family
RSC2_01286	COG1587	Uroporphyrinogen-III synthase
RSC2_01288	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC2_01289	COG0583	DNA-binding transcription factor activity
RSC2_01290	COG2814	Major facilitator Superfamily
RSC2_01292	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RSC2_01292	COG2124	cytochrome p450
RSC2_01293	COG1309	transcriptional regulator
RSC2_01294	COG1404	Belongs to the peptidase S8 family
RSC2_01295	COG1404	Belongs to the peptidase S8 family
RSC2_01296	COG2226	methyltransferase
RSC2_01302	COG0626	cystathionine gamma-synthase activity
RSC2_01303	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RSC2_01304	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RSC2_01305	COG2226	methyltransferase
RSC2_01308	COG0768	penicillin binding
RSC2_01309	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RSC2_01310	COG0572	uridine kinase
RSC2_01311	COG0826	peptidase U32
RSC2_01312	COG0826	peptidase U32
RSC2_01313	COG4122	O-methyltransferase activity
RSC2_01314	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RSC2_01315	COG3906	Belongs to the UPF0473 family
RSC2_01316	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RSC2_01317	COG4472	Bacterial protein of unknown function (DUF965)
RSC2_01318	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RSC2_01319	COG0628	permease
RSC2_01322	COG3881	PFAM PRC-barrel domain
RSC2_01323	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RSC2_01324	COG0457	Tetratricopeptide repeat
RSC2_01325	COG0482	sulfurtransferase activity
RSC2_01326	COG1104	cysteine desulfurase activity
RSC2_01327	COG1959	2 iron, 2 sulfur cluster binding
RSC2_01328	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RSC2_01329	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RSC2_01330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RSC2_01331	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RSC2_01332	COG0124	histidyl-tRNA synthetase
RSC2_01333	COG0124	histidyl-tRNA synthetase
RSC2_01335	COG3103	Sh3 type 3 domain protein
RSC2_01335	COG4991	sh3 domain protein
RSC2_01335	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSC2_01336	COG1490	D-aminoacyl-tRNA deacylase activity
RSC2_01337	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RSC2_01338	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RSC2_01339	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RSC2_01339	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RSC2_01340	COG5416	Lipopolysaccharide assembly protein A domain
RSC2_01341	COG0490	domain, Protein
RSC2_01342	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RSC2_01342	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RSC2_01344	COG2244	polysaccharide biosynthetic process
RSC2_01345	COG2244	polysaccharide biosynthetic process
RSC2_01346	COG2323	membrane
RSC2_01348	COG1862	Preprotein translocase
RSC2_01349	COG0343	queuine tRNA-ribosyltransferase activity
RSC2_01350	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RSC2_01352	COG2255	four-way junction helicase activity
RSC2_01353	COG0632	four-way junction helicase activity
RSC2_01355	COG2112	serine threonine protein kinase
RSC2_01360	COG0642	Histidine kinase
RSC2_01361	COG0745	RESPONSE REGULATOR receiver
RSC2_01363	COG2318	DinB family
RSC2_01364	COG4195	phage-related replication protein
RSC2_01367	COG0217	transcriptional regulatory protein
RSC2_01369	COG1388	LysM domain
RSC2_01370	COG1388	LysM domain
RSC2_01371	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RSC2_01372	COG0157	Belongs to the NadC ModD family
RSC2_01373	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RSC2_01374	COG1104	cysteine desulfurase activity
RSC2_01375	COG1827	regulation of RNA biosynthetic process
RSC2_01376	COG0077	Prephenate dehydratase
RSC2_01377	COG4492	Belongs to the UPF0735 family
RSC2_01378	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RSC2_01379	COG3290	protein histidine kinase activity
RSC2_01380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RSC2_01381	COG2868	ribosomal protein
RSC2_01382	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RSC2_01383	COG1994	Peptidase M50
RSC2_01384	COG0739	heme binding
RSC2_01385	COG3832	glyoxalase III activity
RSC2_01387	COG2894	cell division
RSC2_01388	COG0850	regulation of cytokinetic process
RSC2_01389	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
RSC2_01391	COG1077	Cell shape determining protein MreB Mrl
RSC2_01392	COG2003	Belongs to the UPF0758 family
RSC2_01393	COG0424	maF-like protein
RSC2_01395	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RSC2_01396	COG0285	dihydrofolate synthase activity
RSC2_01397	COG0525	valine-tRNA ligase activity
RSC2_01399	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RSC2_01400	COG1388	LysM domain
RSC2_01401	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RSC2_01402	COG0113	porphobilinogen synthase activity
RSC2_01403	COG1587	Uroporphyrinogen-III synthase
RSC2_01404	COG0181	hydroxymethylbilane synthase activity
RSC2_01405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RSC2_01406	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RSC2_01408	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RSC2_01409	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RSC2_01410	COG1067	ATP-dependent peptidase activity
RSC2_01410	COG0470	DNA polymerase III
RSC2_01412	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RSC2_01413	COG0544	peptidyl-prolyl cis-trans isomerase activity
RSC2_01414	COG0457	Tetratricopeptide repeat
RSC2_01414	COG1477	protein flavinylation
RSC2_01415	COG0066	3-isopropylmalate dehydratase activity
RSC2_01416	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RSC2_01417	COG0473	3-isopropylmalate dehydrogenase activity
RSC2_01418	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RSC2_01419	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RSC2_01420	COG0440	acetolactate synthase activity
RSC2_01421	COG0028	Belongs to the TPP enzyme family
RSC2_01422	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RSC2_01424	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RSC2_01429	COG0622	Phosphoesterase
RSC2_01430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RSC2_01431	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RSC2_01432	COG5401	PFAM Sporulation and spore germination
RSC2_01433	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RSC2_01434	COG1846	Transcriptional regulator
RSC2_01435	COG2197	response regulator
RSC2_01436	COG4221	oxidoreductase activity
RSC2_01437	COG0824	Thioesterase
RSC2_01438	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RSC2_01439	COG1053	succinate dehydrogenase
RSC2_01440	COG2009	succinate dehydrogenase
RSC2_01441	COG1719	4-vinyl reductase, 4VR
RSC2_01442	COG0527	aspartate kinase activity
RSC2_01443	COG0322	excinuclease ABC activity
RSC2_01444	COG3118	belongs to the thioredoxin family
RSC2_01445	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RSC2_01446	COG2086	electron transfer activity
RSC2_01447	COG1024	Enoyl-CoA hydratase
RSC2_01448	COG1309	transcriptional regulator
RSC2_01449	COG0318	PFAM AMP-dependent synthetase and ligase
RSC2_01450	COG3766	membrane
RSC2_01451	COG1193	negative regulation of DNA recombination
RSC2_01452	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RSC2_01452	COG1796	DNA polymerase
RSC2_01453	COG1286	toxin biosynthetic process
RSC2_01454	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
RSC2_01455	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RSC2_01460	COG0072	phenylalanine-tRNA ligase activity
RSC2_01460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RSC2_01461	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RSC2_01462	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RSC2_01464	COG1966	Carbon starvation protein
RSC2_01465	COG1309	transcriptional regulator
RSC2_01466	COG3402	PFAM membrane-flanked domain
RSC2_01470	COG0395	ABC-type sugar transport system, permease component
RSC2_01471	COG1175	transmembrane transport
RSC2_01472	COG1653	transport
RSC2_01473	COG0371	Dehydrogenase
RSC2_01474	COG0235	Class ii aldolase
RSC2_01475	COG1069	ribulokinase activity
RSC2_01476	COG2160	L-arabinose isomerase activity
RSC2_01477	COG3507	Belongs to the glycosyl hydrolase 43 family
RSC2_01478	COG1363	Peptidase, m42
RSC2_01480	COG3326	Membrane
RSC2_01481	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RSC2_01482	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RSC2_01483	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RSC2_01484	COG1346	cytolysis
RSC2_01486	COG3540	Alkaline phosphatase
RSC2_01487	COG3279	Response regulator of the LytR AlgR family
RSC2_01488	COG3275	phosphorelay sensor kinase activity
RSC2_01490	COG1011	Hydrolase
RSC2_01491	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RSC2_01493	COG0398	Pfam SNARE associated Golgi protein
RSC2_01494	COG1484	DNA-dependent DNA replication
RSC2_01495	COG1484	DNA-dependent DNA replication
RSC2_01496	COG3611	Membrane attachment protein
RSC2_01497	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RSC2_01499	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RSC2_01500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RSC2_01502	COG3866	Pectate lyase
RSC2_01503	COG0237	dephospho-CoA kinase activity
RSC2_01504	COG1971	Probably functions as a manganese efflux pump
RSC2_01506	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RSC2_01507	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RSC2_01507	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RSC2_01508	COG5002	protein histidine kinase activity
RSC2_01509	COG0745	RESPONSE REGULATOR receiver
RSC2_01510	COG0039	L-malate dehydrogenase activity
RSC2_01511	COG0538	isocitrate dehydrogenase activity
RSC2_01512	COG0538	isocitrate dehydrogenase activity
RSC2_01513	COG0372	Belongs to the citrate synthase family
RSC2_01515	COG2273	Hydrolase Family 16
RSC2_01517	COG2707	UPF0756 membrane protein
RSC2_01518	COG0628	permease
RSC2_01519	COG3030	protein affecting phage T7 exclusion by the F plasmid
RSC2_01521	COG0205	6-phosphofructokinase activity
RSC2_01522	COG0825	malonyl-CoA metabolic process
RSC2_01523	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RSC2_01524	COG0281	malic enzyme
RSC2_01525	COG0587	DNA-directed DNA polymerase activity
RSC2_01529	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RSC2_01531	COG4109	DRTGG domain
RSC2_01532	COG1695	Transcriptional regulator
RSC2_01533	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RSC2_01534	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_01536	COG0165	Argininosuccinate lyase
RSC2_01537	COG0137	argininosuccinate synthase activity
RSC2_01538	COG0521	Mo-molybdopterin cofactor biosynthetic process
RSC2_01539	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RSC2_01540	COG0827	DNA restriction-modification system
RSC2_01541	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
RSC2_01542	COG3874	Sporulation protein YtfJ
RSC2_01544	COG1714	RDD family
RSC2_01545	COG0616	signal peptide processing
RSC2_01546	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RSC2_01548	COG1846	Transcriptional regulator
RSC2_01549	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RSC2_01551	COG0301	tRNA thio-modification
RSC2_01552	COG1104	cysteine desulfurase activity
RSC2_01553	COG1114	Component of the transport system for branched-chain amino acids
RSC2_01554	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
RSC2_01555	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RSC2_01556	COG1309	transcriptional regulator
RSC2_01557	COG1956	GAF domain-containing protein
RSC2_01558	COG2199	diguanylate cyclase activity
RSC2_01558	COG2203	Gaf domain
RSC2_01559	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RSC2_01562	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RSC2_01563	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RSC2_01564	COG0454	-acetyltransferase
RSC2_01565	COG0517	IMP dehydrogenase activity
RSC2_01566	COG0123	including yeast histone deacetylase and acetoin utilization protein
RSC2_01567	COG1360	Flagellar Motor Protein
RSC2_01568	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RSC2_01569	COG1609	Transcriptional regulator
RSC2_01570	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RSC2_01570	COG1605	Chorismate mutase
RSC2_01572	COG3118	belongs to the thioredoxin family
RSC2_01573	COG4980	gas vesicle protein
RSC2_01574	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
RSC2_01575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RSC2_01577	COG1674	ftsk spoiiie
RSC2_01578	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RSC2_01579	COG4848	Belongs to the UPF0354 family
RSC2_01580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC2_01582	COG1363	Peptidase, m42
RSC2_01583	COG5584	Small secreted protein
RSC2_01584	COG0281	malic enzyme
RSC2_01585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC2_01586	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RSC2_01588	COG0510	thiamine kinase activity
RSC2_01589	COG1523	belongs to the glycosyl hydrolase 13 family
RSC2_01590	COG1597	lipid kinase activity
RSC2_01592	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RSC2_01593	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RSC2_01595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RSC2_01596	COG2252	PERMEase
RSC2_01597	COG4473	ABC transporter
RSC2_01598	COG1131	(ABC) transporter
RSC2_01599	COG1349	DNA-binding transcription factor activity
RSC2_01600	COG1187	pseudouridine synthase activity
RSC2_01601	COG2244	polysaccharide biosynthetic process
RSC2_01602	COG2081	HI0933 family
RSC2_01603	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RSC2_01605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RSC2_01606	COG0457	Tetratricopeptide repeat
RSC2_01609	COG5578	integral membrane protein
RSC2_01610	COG0673	inositol 2-dehydrogenase activity
RSC2_01611	COG1653	transport
RSC2_01612	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RSC2_01613	COG4209	transmembrane transport
RSC2_01614	COG2207	Transcriptional regulator
RSC2_01615	COG1653	transport
RSC2_01616	COG0395	ABC-type sugar transport system, permease component
RSC2_01617	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RSC2_01618	COG1073	alpha beta
RSC2_01620	COG0583	DNA-binding transcription factor activity
RSC2_01621	COG0346	lactoylglutathione lyase activity
RSC2_01622	COG0495	leucyl-tRNA aminoacylation
RSC2_01624	COG2814	Major facilitator Superfamily
RSC2_01625	COG1464	Belongs to the NlpA lipoprotein family
RSC2_01626	COG2433	Pfam Transposase IS66
RSC2_01627	COG0577	efflux transmembrane transporter activity
RSC2_01628	COG1136	(ABC) transporter
RSC2_01630	COG1131	(ABC) transporter
RSC2_01631	COG1725	Transcriptional regulator
RSC2_01634	COG1242	4 iron, 4 sulfur cluster binding
RSC2_01635	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RSC2_01636	COG1301	dicarboxylic acid transport
RSC2_01638	COG2267	carboxylic ester hydrolase activity
RSC2_01639	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RSC2_01640	COG0671	phosphoesterase, PA-phosphatase related
RSC2_01641	COG0438	transferase activity, transferring glycosyl groups
RSC2_01641	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RSC2_01642	COG0367	asparagine synthase
RSC2_01643	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RSC2_01644	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
RSC2_01645	COG1301	dicarboxylic acid transport
RSC2_01647	COG1506	peptidase
RSC2_01648	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RSC2_01649	COG1116	anion transmembrane transporter activity
RSC2_01650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RSC2_01651	COG0494	nUDIX hydrolase
RSC2_01653	COG4824	toxin secretion phage lysis holin
RSC2_01654	COG0783	Belongs to the Dps family
RSC2_01657	COG1854	S-ribosylhomocysteine lyase activity
RSC2_01658	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RSC2_01659	COG0288	reversible hydration of carbon dioxide
RSC2_01660	COG0523	cobalamin synthesis protein
RSC2_01661	COG0803	Belongs to the bacterial solute-binding protein 9 family
RSC2_01663	COG0254	rRNA binding
RSC2_01665	COG1271	oxidase subunit
RSC2_01666	COG1294	oxidase, subunit
RSC2_01669	COG4948	Mandelate Racemase Muconate Lactonizing
RSC2_01670	COG0318	PFAM AMP-dependent synthetase and ligase
RSC2_01671	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RSC2_01672	COG0596	Alpha beta hydrolase
RSC2_01673	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
RSC2_01674	COG1169	isochorismate synthase
RSC2_01675	COG1575	Belongs to the MenA family. Type 1 subfamily
RSC2_01676	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RSC2_01677	COG0058	SHG alpha-glucan phosphorylase activity
RSC2_01678	COG0058	SHG alpha-glucan phosphorylase activity
RSC2_01679	COG0297	glycogen (starch) synthase activity
RSC2_01680	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RSC2_01681	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RSC2_01682	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RSC2_01688	COG1609	Transcriptional regulator
RSC2_01689	COG3859	Proton-coupled thiamine transporter YuaJ
RSC2_01690	COG3764	Sortase (surface protein transpeptidase)
RSC2_01693	COG0457	Tetratricopeptide repeat
RSC2_01695	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
RSC2_01696	COG0569	domain protein
RSC2_01697	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RSC2_01699	COG2318	DinB family
RSC2_01701	COG1454	alcohol dehydrogenase
RSC2_01702	COG1012	belongs to the aldehyde dehydrogenase family
RSC2_01703	COG1510	regulation of RNA biosynthetic process
RSC2_01705	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RSC2_01706	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RSC2_01707	COG2140	Oxalate decarboxylase
RSC2_01708	COG1397	ADP-ribosylglycohydrolase
RSC2_01718	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
RSC2_01721	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RSC2_01722	COG0726	polysaccharide deacetylase
RSC2_01723	COG1408	metallophosphoesterase
RSC2_01724	COG1968	undecaprenyl-diphosphatase activity
RSC2_01725	COG0628	permease
RSC2_01726	COG0673	inositol 2-dehydrogenase activity
RSC2_01727	COG0693	protein deglycase activity
RSC2_01728	COG0840	transmembrane signaling receptor activity
RSC2_01729	COG0840	transmembrane signaling receptor activity
RSC2_01730	COG0840	transmembrane signaling receptor activity
RSC2_01733	COG2070	2-Nitropropane dioxygenase
RSC2_01734	COG0432	Pfam Uncharacterised protein family UPF0047
RSC2_01735	COG0366	Alpha amylase catalytic
RSC2_01738	COG5297	Belongs to the glycosyl hydrolase family 6
RSC2_01739	COG1253	flavin adenine dinucleotide binding
RSC2_01740	COG2738	Putative neutral zinc metallopeptidase
RSC2_01742	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RSC2_01744	COG2323	membrane
RSC2_01745	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
RSC2_01747	COG0166	Belongs to the GPI family
RSC2_01749	COG1979	alcohol dehydrogenase
RSC2_01750	COG2155	Conserved Protein
RSC2_01751	COG1098	S1 RNA binding domain
RSC2_01752	COG0436	Aminotransferase
RSC2_01753	COG1522	sequence-specific DNA binding
RSC2_01754	COG2267	carboxylic ester hydrolase activity
RSC2_01758	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RSC2_01761	COG5018	Exonuclease
RSC2_01762	COG2814	Major facilitator Superfamily
RSC2_01763	COG2814	Major facilitator Superfamily
RSC2_01764	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RSC2_01765	COG3011	Protein conserved in bacteria
RSC2_01767	COG3290	protein histidine kinase activity
RSC2_01768	COG4565	transcriptional regulatory protein
RSC2_01769	COG1183	phosphatidylcholine synthase activity
RSC2_01770	COG0586	Pfam SNARE associated Golgi protein
RSC2_01771	COG0688	phosphatidylethanolamine metabolic process
RSC2_01772	COG3493	citrate carrier protein
RSC2_01774	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RSC2_01774	COG2111	Na H antiporter
RSC2_01775	COG2111	Na H antiporter
RSC2_01776	COG1006	Multisubunit Na H antiporter MnhC subunit
RSC2_01777	COG0651	ATP synthesis coupled electron transport
RSC2_01778	COG1863	multisubunit Na H antiporter MnhE subunit
RSC2_01779	COG2212	antiporter activity
RSC2_01780	COG1320	monovalent cation:proton antiporter activity
RSC2_01781	COG2050	protein possibly involved in aromatic compounds catabolism
RSC2_01782	COG2197	response regulator
RSC2_01783	COG4585	Histidine kinase
RSC2_01784	COG4585	Histidine kinase
RSC2_01786	COG0142	geranyltranstransferase activity
RSC2_01788	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
RSC2_01789	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RSC2_01790	COG1335	isochorismatase
RSC2_01791	COG5506	Protein of unknown function (DUF1694)
RSC2_01794	COG0628	permease
RSC2_01796	COG1418	mRNA catabolic process
RSC2_01797	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_01800	COG1511	domain protein
RSC2_01801	COG1674	ftsk spoiiie
RSC2_01801	COG0433	COG0433 Predicted ATPase
RSC2_01802	COG4499	WXG100 protein secretion system (Wss), protein YukC
RSC2_01803	COG5417	Belongs to the EsaB family
RSC2_01804	COG4842	Belongs to the WXG100 family
RSC2_01805	COG1115	amino acid carrier protein
RSC2_01806	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RSC2_01806	COG2508	Transcriptional regulator
RSC2_01807	COG0686	Belongs to the AlaDH PNT family
RSC2_01809	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RSC2_01811	COG1268	BioY protein
RSC2_01812	COG2056	Na+-H+ antiporter family
RSC2_01813	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RSC2_01814	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
RSC2_01816	COG3584	3D domain protein
RSC2_01819	COG1252	NADH dehydrogenase
RSC2_01820	COG0492	ferredoxin-NADP+ reductase activity
RSC2_01823	COG0454	-acetyltransferase
RSC2_01824	COG0316	Belongs to the HesB IscA family
RSC2_01825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RSC2_01826	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RSC2_01827	COG4844	belongs to the
RSC2_01828	COG1252	NADH dehydrogenase
RSC2_01829	COG5646	InterPro IPR014922
RSC2_01833	COG0457	Tetratricopeptide repeat
RSC2_01834	COG3479	Phenolic acid decarboxylase
RSC2_01836	COG4837	Protein of unknown function (DUF1462)
RSC2_01837	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RSC2_01838	COG0823	Involved in the tonB-independent uptake of proteins
RSC2_01838	COG1506	peptidase
RSC2_01838	COG4946	Tricorn protease homolog
RSC2_01839	COG0083	homoserine kinase activity
RSC2_01840	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RSC2_01841	COG0460	homoserine dehydrogenase
RSC2_01842	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RSC2_01843	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RSC2_01844	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RSC2_01845	COG0647	UMP catabolic process
RSC2_01846	COG2445	Protein of unknown function DUF86
RSC2_01847	COG4470	Protein conserved in bacteria
RSC2_01850	COG0739	heme binding
RSC2_01852	COG0733	neurotransmitter:sodium symporter activity
RSC2_01854	COG3377	Domain of unknown function (DUF1805)
RSC2_01855	COG0737	Belongs to the 5'-nucleotidase family
RSC2_01856	COG0730	response to heat
RSC2_01857	COG1801	Protein of unknown function DUF72
RSC2_01859	COG3226	Transcriptional regulator
RSC2_01861	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RSC2_01862	COG2508	Transcriptional regulator
RSC2_01863	COG2814	Major facilitator Superfamily
RSC2_01864	COG1288	antiporter activity
RSC2_01866	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RSC2_01867	COG2356	endonuclease I
RSC2_01869	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RSC2_01874	COG0457	Tetratricopeptide repeat
RSC2_01876	COG0719	Fe-S assembly protein
RSC2_01877	COG0822	iron-sulfur transferase activity
RSC2_01878	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RSC2_01879	COG0719	Fe-S assembly protein
RSC2_01880	COG0396	ATPase activity
RSC2_01882	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RSC2_01883	COG1464	Belongs to the NlpA lipoprotein family
RSC2_01884	COG2011	ABC-type metal ion transport system permease component
RSC2_01885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RSC2_01887	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC2_01888	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RSC2_01890	COG0509	glycine decarboxylation via glycine cleavage system
RSC2_01891	COG1393	Belongs to the ArsC family
RSC2_01892	COG1960	acyl-CoA dehydrogenase activity
RSC2_01893	COG0183	Belongs to the thiolase family
RSC2_01894	COG1024	Enoyl-CoA hydratase
RSC2_01894	COG1250	3-hydroxyacyl-CoA dehydrogenase
RSC2_01897	COG5577	PFAM Coat F domain
RSC2_01900	COG1120	ATPase activity
RSC2_01901	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC2_01902	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC2_01903	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC2_01906	COG1686	Belongs to the peptidase S11 family
RSC2_01907	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_01908	COG0783	Belongs to the Dps family
RSC2_01909	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RSC2_01910	COG0745	RESPONSE REGULATOR receiver
RSC2_01911	COG2770	Histidine kinase
RSC2_01911	COG2205	protein histidine kinase activity
RSC2_01913	COG1309	transcriptional regulator
RSC2_01914	COG0114	fumarate hydratase activity
RSC2_01916	COG0697	spore germination
RSC2_01917	COG0814	amino acid
RSC2_01920	COG2197	response regulator
RSC2_01921	COG4585	Histidine kinase
RSC2_01922	COG4758	membrane
RSC2_01923	COG3595	metallopeptidase activity
RSC2_01924	COG1842	Phage shock protein A
RSC2_01925	COG4758	membrane
RSC2_01926	COG4677	pectinesterase activity
RSC2_01927	COG2096	Adenosyltransferase
RSC2_01928	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_01929	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RSC2_01930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RSC2_01933	COG1454	alcohol dehydrogenase
RSC2_01934	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RSC2_01935	COG1120	ATPase activity
RSC2_01936	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC2_01937	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC2_01938	COG1802	Transcriptional regulator
RSC2_01939	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_01940	COG2258	MOSC domain
RSC2_01941	COG0583	DNA-binding transcription factor activity
RSC2_01943	COG2721	sulfolactate sulfo-lyase activity
RSC2_01944	COG0246	Mannitol dehydrogenase
RSC2_01945	COG1609	Transcriptional regulator
RSC2_01946	COG2211	Major facilitator Superfamily
RSC2_01947	COG2211	Major facilitator Superfamily
RSC2_01948	COG1904	glucuronate isomerase
RSC2_01949	COG2205	protein histidine kinase activity
RSC2_01950	COG0745	RESPONSE REGULATOR receiver
RSC2_01951	COG1120	ATPase activity
RSC2_01952	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC2_01953	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC2_01954	COG0531	amino acid
RSC2_01957	COG1988	membrane-bound metal-dependent
RSC2_01958	COG1368	sulfuric ester hydrolase activity
RSC2_01959	COG2814	Major facilitator Superfamily
RSC2_01960	COG0656	L-ascorbic acid biosynthetic process
RSC2_01961	COG1940	carbohydrate kinase activity
RSC2_01962	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RSC2_01964	COG0596	Alpha beta hydrolase
RSC2_01965	COG3973	AAA domain
RSC2_01966	COG2860	membrane
RSC2_01967	COG0456	acetyltransferase
RSC2_01967	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RSC2_01969	COG0456	acetyltransferase
RSC2_01970	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RSC2_01971	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RSC2_01972	COG2217	Heavy metal translocating P-type atpase
RSC2_01973	COG1653	transport
RSC2_01974	COG1175	transmembrane transport
RSC2_01975	COG0395	ABC-type sugar transport system, permease component
RSC2_01976	COG1501	Belongs to the glycosyl hydrolase 31 family
RSC2_01977	COG1501	Belongs to the glycosyl hydrolase 31 family
RSC2_01978	COG1472	Belongs to the glycosyl hydrolase 3 family
RSC2_01979	COG1121	(ABC) transporter
RSC2_01980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RSC2_01981	COG0803	Belongs to the bacterial solute-binding protein 9 family
RSC2_01984	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSC2_01984	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSC2_01984	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC2_01985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC2_01988	COG2217	Heavy metal translocating P-type atpase
RSC2_01989	COG2608	mercury ion transmembrane transporter activity
RSC2_01990	COG1937	Protein conserved in bacteria
RSC2_01991	COG0693	protein deglycase activity
RSC2_01992	COG1349	DNA-binding transcription factor activity
RSC2_01993	COG1070	Carbohydrate kinase
RSC2_01994	COG4952	isomerase
RSC2_01996	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_01996	COG3347	Dehydrogenase
RSC2_01997	COG2814	Major facilitator Superfamily
RSC2_01998	COG2814	Major facilitator Superfamily
RSC2_02000	COG2124	cytochrome p450
RSC2_02002	COG1846	Transcriptional regulator
RSC2_02004	COG0673	inositol 2-dehydrogenase activity
RSC2_02005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RSC2_02006	COG1054	Belongs to the UPF0176 family
RSC2_02008	COG1191	sigma factor activity
RSC2_02010	COG2140	Oxalate decarboxylase
RSC2_02014	COG5520	Belongs to the glycosyl hydrolase 30 family
RSC2_02015	COG3507	Belongs to the glycosyl hydrolase 43 family
RSC2_02019	COG5444	nuclease activity
RSC2_02023	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RSC2_02024	COG0557	exoribonuclease II activity
RSC2_02025	COG1647	Serine aminopeptidase, S33
RSC2_02026	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RSC2_02027	COG2002	toxin-antitoxin pair type II binding
RSC2_02028	COG1476	TRANSCRIPTIONal
RSC2_02029	COG1396	sequence-specific DNA binding
RSC2_02030	COG1396	sequence-specific DNA binding
RSC2_02031	COG1174	glycine betaine transport
RSC2_02032	COG1732	Glycine betaine
RSC2_02033	COG1174	glycine betaine transport
RSC2_02034	COG1125	glycine betaine transport
RSC2_02034	COG0517	IMP dehydrogenase activity
RSC2_02035	COG1510	regulation of RNA biosynthetic process
RSC2_02036	COG2095	MarC family integral membrane protein
RSC2_02037	COG3064	Membrane
RSC2_02038	COG4640	response to antibiotic
RSC2_02039	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC2_02044	COG0693	protein deglycase activity
RSC2_02045	COG0148	phosphopyruvate hydratase activity
RSC2_02046	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
RSC2_02047	COG0149	triose-phosphate isomerase activity
RSC2_02048	COG0126	phosphoglycerate kinase activity
RSC2_02049	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RSC2_02050	COG2390	Transcriptional regulator
RSC2_02051	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RSC2_02052	COG1113	amino acid transport
RSC2_02056	COG1556	Lactate utilization protein
RSC2_02057	COG1139	Iron-sulfur cluster binding protein
RSC2_02058	COG0247	lactate metabolic process
RSC2_02059	COG2186	Transcriptional regulator
RSC2_02060	COG1620	l-lactate permease
RSC2_02061	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RSC2_02063	COG5039	Polysaccharide pyruvyl transferase
RSC2_02064	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RSC2_02065	COG0110	maltose O-acetyltransferase activity
RSC2_02066	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RSC2_02067	COG2244	polysaccharide biosynthetic process
RSC2_02068	COG1216	Glycosyl transferase, family 2
RSC2_02069	COG5039	Polysaccharide pyruvyl transferase
RSC2_02070	COG1216	Glycosyl transferase, family 2
RSC2_02072	COG0438	transferase activity, transferring glycosyl groups
RSC2_02073	COG1215	transferase activity, transferring glycosyl groups
RSC2_02074	COG0438	transferase activity, transferring glycosyl groups
RSC2_02075	COG1086	Polysaccharide biosynthesis protein
RSC2_02077	COG0489	protein tyrosine kinase activity
RSC2_02078	COG3944	biosynthesis protein
RSC2_02079	COG1396	sequence-specific DNA binding
RSC2_02082	COG2249	NAD(P)H dehydrogenase (quinone) activity
RSC2_02083	COG2271	Major facilitator Superfamily
RSC2_02085	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RSC2_02087	COG1454	alcohol dehydrogenase
RSC2_02088	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RSC2_02090	COG1733	regulation of RNA biosynthetic process
RSC2_02091	COG1902	pentaerythritol trinitrate reductase activity
RSC2_02092	COG1621	beta-fructofuranosidase activity
RSC2_02093	COG1621	beta-fructofuranosidase activity
RSC2_02095	COG0740	serine-type endopeptidase activity
RSC2_02096	COG1611	Belongs to the LOG family
RSC2_02097	COG1694	Mazg nucleotide pyrophosphohydrolase
RSC2_02098	COG1078	dGTPase activity
RSC2_02099	COG0659	secondary active sulfate transmembrane transporter activity
RSC2_02100	COG0288	reversible hydration of carbon dioxide
RSC2_02101	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RSC2_02102	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RSC2_02103	COG0640	Transcriptional regulator
RSC2_02104	COG0640	Transcriptional regulator
RSC2_02106	COG2732	(Barnase) inhibitor
RSC2_02107	COG2162	N-hydroxyarylamine O-acetyltransferase activity
RSC2_02108	COG2162	N-hydroxyarylamine O-acetyltransferase activity
RSC2_02109	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC2_02110	COG1481	regulation of sporulation
RSC2_02111	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RSC2_02112	COG1660	Displays ATPase and GTPase activities
RSC2_02113	COG1051	belongs to the nudix hydrolase family
RSC2_02114	COG0492	ferredoxin-NADP+ reductase activity
RSC2_02115	COG0457	Tetratricopeptide repeat
RSC2_02116	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RSC2_02117	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RSC2_02117	COG0140	phosphoribosyl-ATP diphosphatase activity
RSC2_02118	COG0107	imidazoleglycerol-phosphate synthase activity
RSC2_02119	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RSC2_02120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RSC2_02121	COG0131	Imidazoleglycerol-phosphate dehydratase
RSC2_02122	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RSC2_02123	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RSC2_02124	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
RSC2_02125	COG4990	cell redox homeostasis
RSC2_02126	COG5297	Belongs to the glycosyl hydrolase family 6
RSC2_02127	COG5297	Belongs to the glycosyl hydrolase family 6
RSC2_02128	COG0110	maltose O-acetyltransferase activity
RSC2_02129	COG0546	phosphoglycolate phosphatase activity
RSC2_02130	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
RSC2_02131	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RSC2_02132	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
RSC2_02133	COG1846	Transcriptional regulator
RSC2_02134	COG2814	Major facilitator Superfamily
RSC2_02135	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RSC2_02136	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RSC2_02137	COG1950	PFAM Membrane protein of
RSC2_02138	COG1983	PspC domain protein
RSC2_02139	COG3595	metallopeptidase activity
RSC2_02143	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RSC2_02144	COG0556	nucleotide-excision repair
RSC2_02145	COG0556	nucleotide-excision repair
RSC2_02146	COG4897	Protein conserved in bacteria
RSC2_02148	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RSC2_02150	COG0793	Belongs to the peptidase S41A family
RSC2_02150	COG3409	Peptidoglycan-binding domain 1 protein
RSC2_02151	COG0473	3-isopropylmalate dehydrogenase activity
RSC2_02152	COG0791	NLP P60 protein
RSC2_02152	COG3883	PFAM NLP P60 protein
RSC2_02153	COG2177	Part of the ABC transporter FtsEX involved in
RSC2_02154	COG2884	Cell division ATP-binding protein ftsE
RSC2_02156	COG2010	Cytochrome c
RSC2_02157	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC2_02158	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RSC2_02159	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RSC2_02160	COG0653	protein targeting
RSC2_02161	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RSC2_02164	COG1516	flagellar protein fliS
RSC2_02165	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
RSC2_02166	COG1334	flagellar protein FlaG
RSC2_02168	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RSC2_02169	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
RSC2_02170	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
RSC2_02172	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RSC2_02173	COG1256	bacterial-type flagellum assembly
RSC2_02173	COG4786	Flagellar basal body rod
RSC2_02174	COG3418	PFAM FlgN family protein
RSC2_02175	COG2747	anti-sigma28 factor FlgM
RSC2_02177	COG1040	competence protein
RSC2_02179	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RSC2_02180	COG1307	EDD domain protein, DegV family
RSC2_02181	COG2197	response regulator
RSC2_02182	COG4585	Histidine kinase
RSC2_02183	COG1739	Uncharacterized protein family UPF0029
RSC2_02184	COG1316	TRANSCRIPTIONal
RSC2_02186	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RSC2_02187	COG0438	transferase activity, transferring glycosyl groups
RSC2_02188	COG1215	transferase activity, transferring glycosyl groups
RSC2_02189	COG3206	protein involved in exopolysaccharide biosynthesis
RSC2_02190	COG3307	-O-antigen
RSC2_02191	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RSC2_02192	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RSC2_02193	COG0297	glycogen (starch) synthase activity
RSC2_02193	COG0438	transferase activity, transferring glycosyl groups
RSC2_02194	COG2244	polysaccharide biosynthetic process
RSC2_02196	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSC2_02196	COG2247	cell wall binding repeat
RSC2_02197	COG2247	cell wall binding repeat
RSC2_02197	COG2385	sporulation resulting in formation of a cellular spore
RSC2_02199	COG1316	TRANSCRIPTIONal
RSC2_02200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RSC2_02201	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RSC2_02202	COG1215	transferase activity, transferring glycosyl groups
RSC2_02202	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RSC2_02203	COG1215	transferase activity, transferring glycosyl groups
RSC2_02203	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RSC2_02204	COG0463	Glycosyl transferase, family 2
RSC2_02205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RSC2_02206	COG1134	teichoic acid transport
RSC2_02207	COG1682	transport, permease protein
RSC2_02209	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RSC2_02210	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RSC2_02211	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RSC2_02212	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RSC2_02213	COG4193	domain, Protein
RSC2_02214	COG4193	domain, Protein
RSC2_02215	COG1482	cell wall glycoprotein biosynthetic process
RSC2_02220	COG0800	Aldolase
RSC2_02221	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RSC2_02222	COG1609	Transcriptional regulator
RSC2_02223	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
RSC2_02224	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_02225	COG1063	alcohol dehydrogenase
RSC2_02227	COG2814	Major facilitator Superfamily
RSC2_02228	COG1316	TRANSCRIPTIONal
RSC2_02229	COG0561	phosphatase activity
RSC2_02230	COG0791	NLP P60 protein
RSC2_02232	COG2843	Capsule synthesis protein
RSC2_02234	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RSC2_02235	COG1609	Transcriptional regulator
RSC2_02236	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RSC2_02237	COG1869	D-ribose catabolic process
RSC2_02238	COG1129	ABC transporter
RSC2_02239	COG1172	Belongs to the binding-protein-dependent transport system permease family
RSC2_02240	COG1879	ABC-type sugar transport system periplasmic component
RSC2_02241	COG0583	DNA-binding transcription factor activity
RSC2_02242	COG2226	methyltransferase
RSC2_02243	COG3527	Alpha-acetolactate decarboxylase
RSC2_02244	COG0028	Belongs to the TPP enzyme family
RSC2_02245	COG0583	DNA-binding transcription factor activity
RSC2_02246	COG0583	DNA-binding transcription factor activity
RSC2_02247	COG0405	Gamma-glutamyltransferase
RSC2_02248	COG1522	sequence-specific DNA binding
RSC2_02249	COG2059	Chromate
RSC2_02250	COG2059	Chromate
RSC2_02251	COG4464	protein tyrosine phosphatase activity
RSC2_02252	COG3944	biosynthesis protein
RSC2_02254	COG4715	Zinc finger, swim domain protein
RSC2_02255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RSC2_02256	COG3878	Protein conserved in bacteria
RSC2_02257	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RSC2_02260	COG0561	phosphatase activity
RSC2_02261	COG1349	DNA-binding transcription factor activity
RSC2_02263	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_02265	COG3732	PTS system glucitol sorbitol-specific
RSC2_02269	COG0629	single-stranded DNA binding
RSC2_02272	COG1970	mechanosensitive ion channel activity
RSC2_02273	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RSC2_02274	COG4786	Flagellar basal body rod
RSC2_02275	COG4786	Flagellar basal body rod
RSC2_02276	COG1077	Cell shape determining protein MreB Mrl
RSC2_02277	COG1609	Transcriptional regulator
RSC2_02278	COG1846	Transcriptional regulator
RSC2_02279	COG2814	Major facilitator Superfamily
RSC2_02280	COG0671	phosphoesterase, PA-phosphatase related
RSC2_02281	COG1227	inorganic diphosphatase activity
RSC2_02282	COG3546	catalase activity
RSC2_02283	COG3361	conserved protein (COG2071)
RSC2_02286	COG0517	IMP dehydrogenase activity
RSC2_02287	COG0598	Magnesium transport protein CorA
RSC2_02288	COG1253	flavin adenine dinucleotide binding
RSC2_02289	COG0004	ammonium transporteR
RSC2_02290	COG0004	ammonium transporteR
RSC2_02291	COG0347	Belongs to the P(II) protein family
RSC2_02292	COG0740	serine-type endopeptidase activity
RSC2_02294	COG0739	heme binding
RSC2_02295	COG1247	-acetyltransferase
RSC2_02297	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RSC2_02298	COG0477	Major facilitator Superfamily
RSC2_02299	COG3251	PFAM MbtH domain protein
RSC2_02300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC2_02301	COG1535	isochorismatase
RSC2_02301	COG3433	isochorismatase activity
RSC2_02302	COG1021	2,3-dihydroxybenzoate-AMP ligase
RSC2_02303	COG1169	isochorismate synthase
RSC2_02304	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_02305	COG2819	hydrolase of the alpha beta superfamily
RSC2_02306	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC2_02307	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC2_02308	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC2_02309	COG2207	Transcriptional regulator
RSC2_02309	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC2_02311	COG2910	NAD(P)H-binding
RSC2_02312	COG1959	2 iron, 2 sulfur cluster binding
RSC2_02314	COG1994	Peptidase M50
RSC2_02315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RSC2_02316	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RSC2_02317	COG2223	nitrite transmembrane transporter activity
RSC2_02318	COG3383	formate dehydrogenase (NAD+) activity
RSC2_02319	COG2304	oxidoreductase activity
RSC2_02320	COG2304	oxidoreductase activity
RSC2_02321	COG2385	sporulation resulting in formation of a cellular spore
RSC2_02322	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RSC2_02324	COG4836	Membrane
RSC2_02325	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RSC2_02326	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RSC2_02327	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RSC2_02328	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RSC2_02329	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RSC2_02330	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RSC2_02332	COG0356	it plays a direct role in the translocation of protons across the membrane
RSC2_02334	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RSC2_02335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RSC2_02336	COG4475	Protein of unknown function (DUF436)
RSC2_02337	COG0698	ribose 5-phosphate isomerase
RSC2_02338	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RSC2_02339	COG1971	Probably functions as a manganese efflux pump
RSC2_02340	COG0009	L-threonylcarbamoyladenylate synthase
RSC2_02341	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RSC2_02343	COG0738	Major facilitator superfamily
RSC2_02344	COG0673	inositol 2-dehydrogenase activity
RSC2_02345	COG0561	phosphatase activity
RSC2_02346	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RSC2_02347	COG1609	Transcriptional regulator
RSC2_02348	COG2890	protein-(glutamine-N5) methyltransferase activity
RSC2_02349	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RSC2_02350	COG0346	lactoylglutathione lyase activity
RSC2_02351	COG0789	Transcriptional regulator
RSC2_02352	COG0679	Auxin Efflux Carrier
RSC2_02353	COG0281	malic enzyme
RSC2_02354	COG1435	thymidine kinase activity
RSC2_02355	COG0254	rRNA binding
RSC2_02356	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RSC2_02357	COG1494	fructose-1,6-bisphosphatase
RSC2_02358	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RSC2_02359	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RSC2_02360	COG0191	fructose-bisphosphate aldolase activity
RSC2_02361	COG2204	response regulator
RSC2_02362	COG4821	SIS domain
RSC2_02363	COG0504	CTP synthase activity
RSC2_02364	COG3343	RNA polymerase activity
RSC2_02365	COG1960	acyl-CoA dehydrogenase activity
RSC2_02366	COG1960	acyl-CoA dehydrogenase activity
RSC2_02367	COG1250	3-hydroxyacyl-CoA dehydrogenase
RSC2_02368	COG0183	Belongs to the thiolase family
RSC2_02369	COG2181	nitrate reductase activity
RSC2_02369	COG0247	lactate metabolic process
RSC2_02370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RSC2_02372	COG0018	arginyl-trna synthetase
RSC2_02373	COG4506	Protein conserved in bacteria
RSC2_02374	COG0010	Belongs to the arginase family
RSC2_02375	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
RSC2_02376	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RSC2_02378	COG1994	Peptidase M50
RSC2_02379	COG1942	4-Oxalocrotonate Tautomerase
RSC2_02381	COG3465	dGTPase activity
RSC2_02382	COG3465	dGTPase activity
RSC2_02383	COG1078	dGTPase activity
RSC2_02388	COG2814	Major facilitator Superfamily
RSC2_02393	COG1414	Transcriptional regulator
RSC2_02395	COG0280	phosphate acetyltransferase
RSC2_02396	COG3253	May function as heme-dependent peroxidase
RSC2_02398	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RSC2_02402	COG1131	(ABC) transporter
RSC2_02405	COG2363	Small membrane protein
RSC2_02406	COG2233	PERMEase
RSC2_02408	COG1012	belongs to the aldehyde dehydrogenase family
RSC2_02409	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RSC2_02410	COG1216	Glycosyl transferase, family 2
RSC2_02411	COG0351	phosphomethylpyrimidine kinase
RSC2_02413	COG1621	beta-fructofuranosidase activity
RSC2_02414	COG1263	PTS System
RSC2_02414	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_02415	COG3711	transcriptional antiterminator
RSC2_02417	COG1404	Belongs to the peptidase S8 family
RSC2_02419	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RSC2_02421	COG0778	Nitroreductase
RSC2_02422	COG1473	amidohydrolase
RSC2_02423	COG0772	Belongs to the SEDS family
RSC2_02424	COG0772	Belongs to the SEDS family
RSC2_02425	COG3314	Sporulation integral membrane protein YlbJ
RSC2_02429	COG0456	acetyltransferase
RSC2_02432	COG1132	(ABC) transporter
RSC2_02433	COG1132	(ABC) transporter
RSC2_02440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RSC2_02442	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RSC2_02443	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RSC2_02444	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RSC2_02446	COG0655	NAD(P)H dehydrogenase (quinone) activity
RSC2_02447	COG3162	membrane
RSC2_02448	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC2_02449	COG1070	Carbohydrate kinase
RSC2_02450	COG2115	Belongs to the xylose isomerase family
RSC2_02451	COG1940	carbohydrate kinase activity
RSC2_02452	COG0352	thiamine-phosphate diphosphorylase activity
RSC2_02453	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
RSC2_02454	COG0583	DNA-binding transcription factor activity
RSC2_02457	COG1380	Effector of murein hydrolase LrgA
RSC2_02458	COG1346	cytolysis
RSC2_02460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC2_02461	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RSC2_02462	COG0346	lactoylglutathione lyase activity
RSC2_02463	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RSC2_02464	COG1442	glycosyl transferase family 8
RSC2_02468	COG4585	Histidine kinase
RSC2_02469	COG2197	response regulator
RSC2_02470	COG2409	Drug exporters of the RND superfamily
RSC2_02471	COG5522	Integral membrane protein (intg_mem_TP0381)
RSC2_02472	COG2271	Major facilitator Superfamily
RSC2_02473	COG4948	Mandelate Racemase Muconate Lactonizing
RSC2_02474	COG0800	Aldolase
RSC2_02475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RSC2_02477	COG2234	aminopeptidase activity
RSC2_02478	COG0477	Major facilitator Superfamily
RSC2_02480	COG2357	RelA SpoT domain protein
RSC2_02482	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC2_02483	COG1696	Membrane protein involved in D-alanine export
RSC2_02484	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RSC2_02485	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RSC2_02486	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RSC2_02487	COG2814	Major facilitator Superfamily
RSC2_02488	COG1486	melibiose metabolic process
RSC2_02489	COG1447	Phosphotransferase system cellobiose-specific component IIA
RSC2_02490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC2_02491	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC2_02492	COG3711	transcriptional antiterminator
RSC2_02492	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC2_02494	COG2094	Belongs to the DNA glycosylase MPG family
RSC2_02496	COG0372	Belongs to the citrate synthase family
RSC2_02497	COG2079	MmgE PrpD family protein
RSC2_02498	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RSC2_02501	COG1132	(ABC) transporter
RSC2_02502	COG2755	lipolytic protein G-D-S-L family
RSC2_02505	COG2814	Major facilitator Superfamily
RSC2_02507	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RSC2_02508	COG1131	(ABC) transporter
RSC2_02512	COG1595	DNA-templated transcription, initiation
RSC2_02513	COG2814	Major facilitator Superfamily
RSC2_02515	COG0753	catalase activity
RSC2_02516	COG0753	catalase activity
RSC2_02517	COG0735	belongs to the Fur family
RSC2_02518	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RSC2_02520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RSC2_02521	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RSC2_02522	COG4988	ABC transporter
RSC2_02523	COG1294	oxidase, subunit
RSC2_02524	COG1271	oxidase subunit
RSC2_02525	COG2116	formate transmembrane transporter activity
RSC2_02527	COG0281	malic enzyme
RSC2_02528	COG1757	Na H antiporter
RSC2_02529	COG1027	Aspartate ammonia-lyase
RSC2_02530	COG0252	asparaginase activity
RSC2_02531	COG1396	sequence-specific DNA binding
RSC2_02532	COG2706	6-phosphogluconolactonase activity
RSC2_02533	COG0745	RESPONSE REGULATOR receiver
RSC2_02534	COG2205	protein histidine kinase activity
RSC2_02535	COG1136	(ABC) transporter
RSC2_02536	COG1136	(ABC) transporter
RSC2_02537	COG0577	efflux transmembrane transporter activity
RSC2_02538	COG5294	Protein conserved in bacteria
RSC2_02541	COG0726	polysaccharide deacetylase
RSC2_02542	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC2_02544	COG3493	citrate carrier protein
RSC2_02545	COG0584	glycerophosphoryl diester phosphodiesterase
RSC2_02548	COG1368	sulfuric ester hydrolase activity
RSC2_02550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC2_02552	COG2235	arginine
RSC2_02553	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RSC2_02555	COG0549	Belongs to the carbamate kinase family
RSC2_02557	COG2723	6-phospho-beta-galactosidase activity
RSC2_02558	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC2_02560	COG1595	DNA-templated transcription, initiation
RSC2_02562	COG2195	Cleaves the N-terminal amino acid of tripeptides
RSC2_02564	COG2223	nitrite transmembrane transporter activity
RSC2_02565	COG0395	ABC-type sugar transport system, permease component
RSC2_02566	COG1175	transmembrane transport
RSC2_02568	COG1609	Transcriptional regulator
RSC2_02571	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RSC2_02572	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RSC2_02573	COG0463	Glycosyl transferase, family 2
RSC2_02574	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RSC2_02579	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RSC2_02580	COG0693	protein deglycase activity
RSC2_02580	COG0753	catalase activity
RSC2_02582	COG2723	6-phospho-beta-galactosidase activity
RSC2_02583	COG1263	PTS System
RSC2_02583	COG2190	(PTS) system
RSC2_02583	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_02584	COG1263	PTS System
RSC2_02584	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_02584	COG2190	(PTS) system
RSC2_02585	COG3711	transcriptional antiterminator
RSC2_02586	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RSC2_02587	COG1122	ATPase activity
RSC2_02588	COG4721	ABC-type cobalt transport system, permease component
RSC2_02589	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RSC2_02592	COG2224	Isocitrate lyase
RSC2_02593	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RSC2_02595	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RSC2_02605	COG0577	efflux transmembrane transporter activity
RSC2_02606	COG1136	(ABC) transporter
RSC2_02607	COG2205	protein histidine kinase activity
RSC2_02608	COG0745	RESPONSE REGULATOR receiver
RSC2_02609	COG2723	6-phospho-beta-galactosidase activity
RSC2_02610	COG1263	PTS System
RSC2_02610	COG2190	(PTS) system
RSC2_02610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_02612	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
RSC2_02613	COG3507	Belongs to the glycosyl hydrolase 43 family
RSC2_02614	COG0513	Belongs to the DEAD box helicase family
RSC2_02617	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
RSC2_02618	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RSC2_02619	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RSC2_02620	COG2390	Transcriptional regulator
RSC2_02622	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
RSC2_02623	COG3706	GGDEF domain
RSC2_02624	COG5298	Protein conserved in bacteria
RSC2_02625	COG1215	transferase activity, transferring glycosyl groups
RSC2_02627	COG3977	Valine--pyruvate aminotransferase
RSC2_02630	COG1181	Belongs to the D-alanine--D-alanine ligase family
RSC2_02632	COG0191	fructose-bisphosphate aldolase activity
RSC2_02633	COG1082	Xylose isomerase domain protein TIM barrel
RSC2_02634	COG1082	Xylose isomerase domain protein TIM barrel
RSC2_02635	COG0673	inositol 2-dehydrogenase activity
RSC2_02636	COG2814	Major facilitator Superfamily
RSC2_02637	COG1082	Xylose isomerase domain protein TIM barrel
RSC2_02638	COG3962	Belongs to the TPP enzyme family
RSC2_02639	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RSC2_02640	COG3718	enzyme involved in inositol metabolism
RSC2_02641	COG1012	belongs to the aldehyde dehydrogenase family
RSC2_02642	COG1349	DNA-binding transcription factor activity
RSC2_02643	COG0667	Aldo Keto reductase
RSC2_02644	COG0584	glycerophosphoryl diester phosphodiesterase
RSC2_02645	COG2271	Major facilitator Superfamily
RSC2_02646	COG0326	Molecular chaperone. Has ATPase activity
RSC2_02647	COG0488	(ABC) transporter
RSC2_02648	COG0561	phosphatase activity
RSC2_02652	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC2_02658	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
RSC2_02659	COG0577	efflux transmembrane transporter activity
RSC2_02660	COG1136	(ABC) transporter
RSC2_02661	COG1136	(ABC) transporter
RSC2_02662	COG2205	protein histidine kinase activity
RSC2_02663	COG0745	RESPONSE REGULATOR receiver
RSC2_02665	COG5278	phosphoserine phosphatase activity
RSC2_02665	COG0840	transmembrane signaling receptor activity
RSC2_02666	COG1115	amino acid carrier protein
RSC2_02667	COG0686	Belongs to the AlaDH PNT family
RSC2_02668	COG3867	Arabinogalactan endo-beta-1,4-galactanase
RSC2_02669	COG1874	Beta-galactosidase
RSC2_02670	COG3833	ABC-type maltose transport systems, permease component
RSC2_02671	COG1175	transmembrane transport
RSC2_02672	COG2182	Extracellular solute-binding protein
RSC2_02673	COG1609	Transcriptional regulator
RSC2_02675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RSC2_02676	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
RSC2_02677	COG1940	carbohydrate kinase activity
RSC2_02679	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RSC2_02685	COG1012	belongs to the aldehyde dehydrogenase family
RSC2_02685	COG1454	alcohol dehydrogenase
RSC2_02686	COG0450	alkyl hydroperoxide reductase
RSC2_02687	COG3634	alkyl hydroperoxide reductase activity
RSC2_02689	COG1113	amino acid transport
RSC2_02690	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
RSC2_02691	COG3634	alkyl hydroperoxide reductase activity
RSC2_02692	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC2_02693	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC2_02694	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC2_02697	COG1131	(ABC) transporter
RSC2_02698	COG0842	Transport permease protein
RSC2_02699	COG4585	Histidine kinase
RSC2_02700	COG2197	response regulator
RSC2_02704	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RSC2_02707	COG0456	acetyltransferase
RSC2_02710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RSC2_02711	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RSC2_02712	COG4853	Protein conserved in bacteria
RSC2_02713	COG4863	YycH protein
RSC2_02714	COG5002	protein histidine kinase activity
RSC2_02715	COG0745	RESPONSE REGULATOR receiver
RSC2_02716	COG1051	belongs to the nudix hydrolase family
RSC2_02717	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RSC2_02719	COG0305	Participates in initiation and elongation during chromosome replication
RSC2_02722	COG3093	addiction module antidote protein HigA
RSC2_02723	COG2807	transmembrane transport
RSC2_02724	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RSC2_02725	COG0363	glucosamine-6-phosphate deaminase activity
RSC2_02726	COG2188	Transcriptional regulator
RSC2_02727	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
RSC2_02728	COG1263	PTS System
RSC2_02728	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_02729	COG0359	binds to the 23S rRNA
RSC2_02730	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RSC2_02731	COG4241	membrane
RSC2_02734	COG5577	PFAM Coat F domain
RSC2_02735	COG0589	response to stress
RSC2_02736	COG0659	secondary active sulfate transmembrane transporter activity
RSC2_02737	COG2271	Major facilitator Superfamily
RSC2_02738	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RSC2_02739	COG0629	single-stranded DNA binding
RSC2_02740	COG0360	Binds together with S18 to 16S ribosomal RNA
RSC2_02741	COG0012	GTP binding
RSC2_02742	COG4481	Protein conserved in bacteria
RSC2_02743	COG3949	Membrane
RSC2_02745	COG1475	DNA binding
RSC2_02746	COG1192	Involved in chromosome partitioning
RSC2_02747	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RSC2_02748	COG1595	DNA-templated transcription, initiation
RSC2_02749	COG1475	DNA binding
RSC2_02750	COG0357	Ribosomal RNA small subunit methyltransferase G
RSC2_02751	COG0445	tRNA wobble uridine modification
RSC2_02752	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RSC2_02753	COG1847	R3H domain protein
RSC2_02754	COG0706	membrane insertase activity
RSC2_02755	COG0594	ribonuclease P activity
RSC2_02757	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RSC2_02758	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RSC2_02759	COG0592	DNA-directed DNA polymerase activity
RSC2_02761	COG2501	S4 domain
RSC2_02762	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RSC2_02764	COG0187	DNA topoisomerase II activity
RSC2_02765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RSC2_02770	COG0517	IMP dehydrogenase activity
RSC2_02770	COG0516	GMP reductase activity
RSC2_02771	COG1686	Belongs to the peptidase S11 family
RSC2_02772	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
RSC2_02773	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
RSC2_02774	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RSC2_02775	COG1929	Belongs to the glycerate kinase type-1 family
RSC2_02776	COG2610	gluconate transmembrane transporter activity
RSC2_02777	COG3835	regulator
RSC2_02779	COG1428	Deoxynucleoside kinase
RSC2_02780	COG1428	Deoxynucleoside kinase
RSC2_02781	COG1388	LysM domain
RSC2_02781	COG3858	chitin binding
RSC2_02782	COG1388	LysM domain
RSC2_02782	COG3858	chitin binding
RSC2_02783	COG1335	isochorismatase
RSC2_02784	COG0590	tRNA wobble adenosine to inosine editing
RSC2_02785	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RSC2_02786	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RSC2_02787	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RSC2_02794	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
RSC2_02795	COG3853	Toxic anion resistance protein (TelA)
RSC2_02796	COG1982	Orn Lys Arg decarboxylase major
RSC2_02797	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RSC2_02798	COG3870	Protein conserved in bacteria
RSC2_02799	COG1728	Protein conserved in bacteria
RSC2_02800	COG0470	DNA polymerase III
RSC2_02801	COG1774	PSP1 C-terminal conserved region
RSC2_02802	COG4467	Involved in initiation control of chromosome replication
RSC2_02803	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RSC2_02804	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RSC2_02805	COG2002	toxin-antitoxin pair type II binding
RSC2_02806	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RSC2_02806	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RSC2_02807	COG0084	hydrolase, TatD family'
RSC2_02808	COG3583	domain protein
RSC2_02808	COG3584	3D domain protein
RSC2_02809	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RSC2_02810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RSC2_02812	COG4466	Protein conserved in bacteria
RSC2_02814	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RSC2_02815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RSC2_02816	COG0251	oxidation-reduction process
RSC2_02817	COG2088	sporulation resulting in formation of a cellular spore
RSC2_02818	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RSC2_02819	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RSC2_02820	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RSC2_02821	COG0193	aminoacyl-tRNA hydrolase activity
RSC2_02823	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RSC2_02824	COG2002	toxin-antitoxin pair type II binding
RSC2_02825	COG2244	polysaccharide biosynthetic process
RSC2_02826	COG3956	TIGRFAM MazG family protein
RSC2_02827	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RSC2_02829	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
RSC2_02830	COG1098	S1 RNA binding domain
RSC2_02832	COG2208	phosphoserine phosphatase activity
RSC2_02833	COG2304	oxidoreductase activity
RSC2_02834	COG0515	serine threonine protein kinase
RSC2_02835	COG0037	tRNA processing
RSC2_02836	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RSC2_02837	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RSC2_02838	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RSC2_02839	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
RSC2_02840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RSC2_02841	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RSC2_02842	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RSC2_02843	COG0512	Glutamine amidotransferase of anthranilate synthase
RSC2_02844	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RSC2_02845	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RSC2_02846	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RSC2_02847	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RSC2_02848	COG1396	sequence-specific DNA binding
RSC2_02849	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RSC2_02850	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RSC2_02857	COG4463	regulation of RNA biosynthetic process
RSC2_02858	COG3880	PFAM UvrB UvrC protein
RSC2_02859	COG3869	Catalyzes the specific phosphorylation of arginine residues in
RSC2_02860	COG0542	response to heat
RSC2_02861	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RSC2_02862	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
RSC2_02863	COG4956	integral membrane protein (PIN domain superfamily)
RSC2_02864	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RSC2_02865	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RSC2_02866	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RSC2_02867	COG1045	serine acetyltransferase
RSC2_02868	COG0215	cysteine-tRNA ligase activity
RSC2_02869	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RSC2_02870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RSC2_02871	COG3688	RNA-binding protein containing a PIN domain
RSC2_02874	COG0250	Participates in transcription elongation, termination and antitermination
RSC2_02875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RSC2_02876	COG0081	regulation of translation
RSC2_02877	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RSC2_02878	COG0222	ribosome binding
RSC2_02879	COG2813	Specifically methylates the guanine in position
RSC2_02880	COG0085	RNA polymerase activity
RSC2_02881	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RSC2_02882	COG1358	cellular component organization or biogenesis
RSC2_02883	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RSC2_02884	COG0049	tRNA binding
RSC2_02885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RSC2_02886	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RSC2_02888	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RSC2_02889	COG0088	Forms part of the polypeptide exit tunnel
RSC2_02890	COG0089	rRNA binding
RSC2_02892	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RSC2_02893	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RSC2_02894	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RSC2_02895	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RSC2_02896	COG0255	Belongs to the universal ribosomal protein uL29 family
RSC2_02897	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RSC2_02898	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RSC2_02899	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RSC2_02900	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RSC2_02901	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RSC2_02902	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RSC2_02903	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RSC2_02904	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RSC2_02905	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RSC2_02906	COG1841	ribosomal large subunit assembly
RSC2_02907	COG0200	Binds to the 23S rRNA
RSC2_02908	COG0201	protein transport
RSC2_02909	COG0563	adenylate kinase activity
RSC2_02910	COG0024	Methionine aminopeptidase
RSC2_02911	COG2163	COG2163 Ribosomal protein L14E L6E L27E
RSC2_02912	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RSC2_02913	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RSC2_02914	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RSC2_02915	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RSC2_02916	COG0202	RNA polymerase activity
RSC2_02917	COG0203	ribosomal protein L17
RSC2_02918	COG1122	ATPase activity
RSC2_02919	COG1122	ATPase activity
RSC2_02920	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RSC2_02921	COG0101	tRNA pseudouridine synthase activity
RSC2_02922	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RSC2_02923	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RSC2_02924	COG2318	DinB family
RSC2_02927	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSC2_02928	COG0489	protein tyrosine kinase activity
RSC2_02930	COG2194	sulfuric ester hydrolase activity
RSC2_02931	COG0726	polysaccharide deacetylase
RSC2_02936	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RSC2_02938	COG0385	Bile acid
RSC2_02941	COG3876	Protein conserved in bacteria
RSC2_02942	COG1472	Belongs to the glycosyl hydrolase 3 family
RSC2_02943	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RSC2_02944	COG1263	PTS System
RSC2_02944	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_02945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_02945	COG1263	PTS System
RSC2_02946	COG1737	Transcriptional regulator
RSC2_02947	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
RSC2_02948	COG1683	Conserved Protein
RSC2_02950	COG1595	DNA-templated transcription, initiation
RSC2_02951	COG5662	AntiSigma factor
RSC2_02952	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RSC2_02953	COG4856	YbbR-like protein
RSC2_02954	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RSC2_02955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RSC2_02960	COG1725	Transcriptional regulator
RSC2_02962	COG0789	Transcriptional regulator
RSC2_02964	COG0640	Transcriptional regulator
RSC2_02965	COG2814	Major facilitator Superfamily
RSC2_02967	COG1132	(ABC) transporter
RSC2_02968	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RSC2_02970	COG2312	Erythromycin esterase
RSC2_02974	COG1011	Hydrolase
RSC2_02975	COG1113	amino acid transport
RSC2_02977	COG2851	Citrate transporter
RSC2_02978	COG3181	Tripartite tricarboxylate transporter family receptor
RSC2_02979	COG4565	transcriptional regulatory protein
RSC2_02980	COG3290	protein histidine kinase activity
RSC2_02982	COG0583	DNA-binding transcription factor activity
RSC2_02984	COG2211	Major facilitator Superfamily
RSC2_02988	COG1331	Highly conserved protein containing a thioredoxin domain
RSC2_02991	COG0076	glutamate decarboxylase activity
RSC2_02992	COG0778	Nitroreductase
RSC2_02993	COG1802	Transcriptional regulator
RSC2_02994	COG0730	response to heat
RSC2_02998	COG1283	sodium-dependent phosphate transmembrane transporter activity
RSC2_02999	COG4682	membrane
RSC2_03004	COG0697	spore germination
RSC2_03005	COG2207	Transcriptional regulator
RSC2_03005	COG1917	Cupin 2, conserved barrel domain protein
RSC2_03008	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RSC2_03013	COG0371	Dehydrogenase
RSC2_03016	COG4257	antibiotic catabolic process
RSC2_03018	COG0833	amino acid
RSC2_03019	COG2040	homocysteine
RSC2_03021	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_03021	COG1263	PTS System
RSC2_03023	COG2323	membrane
RSC2_03024	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RSC2_03024	COG4451	ribulose bisphosphate carboxylase, small
RSC2_03028	COG2205	protein histidine kinase activity
RSC2_03029	COG1115	amino acid carrier protein
RSC2_03030	COG2066	Belongs to the glutaminase family
RSC2_03031	COG4191	Histidine kinase
RSC2_03032	COG0784	Response regulator, receiver
RSC2_03037	COG3540	Alkaline phosphatase
RSC2_03038	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RSC2_03039	COG0805	protein transport
RSC2_03040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RSC2_03041	COG1012	belongs to the aldehyde dehydrogenase family
RSC2_03042	COG2271	Major facilitator Superfamily
RSC2_03043	COG4948	Mandelate Racemase Muconate Lactonizing
RSC2_03044	COG2186	Transcriptional regulator
RSC2_03045	COG2721	sulfolactate sulfo-lyase activity
RSC2_03049	COG0745	RESPONSE REGULATOR receiver
RSC2_03050	COG2205	protein histidine kinase activity
RSC2_03051	COG1131	(ABC) transporter
RSC2_03056	COG3173	Aminoglycoside phosphotransferase
RSC2_03057	COG1846	Transcriptional regulator
RSC2_03058	COG0318	PFAM AMP-dependent synthetase and ligase
RSC2_03062	COG0789	Transcriptional regulator
RSC2_03067	COG0697	spore germination
RSC2_03068	COG1405	negative regulation of cell septum assembly
RSC2_03068	COG3012	SEC-C Motif Domain Protein
RSC2_03069	COG1131	(ABC) transporter
RSC2_03074	COG0583	DNA-binding transcription factor activity
RSC2_03075	COG1942	4-Oxalocrotonate Tautomerase
RSC2_03076	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_03079	COG1288	antiporter activity
RSC2_03081	COG0252	asparaginase activity
RSC2_03082	COG0456	acetyltransferase
RSC2_03084	COG1164	Oligoendopeptidase f
RSC2_03085	COG2261	transglycosylase associated protein
RSC2_03087	COG0247	lactate metabolic process
RSC2_03088	COG0277	FAD linked oxidase domain protein
RSC2_03089	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC2_03090	COG1447	Phosphotransferase system cellobiose-specific component IIA
RSC2_03091	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC2_03093	COG1486	melibiose metabolic process
RSC2_03094	COG2188	Transcriptional regulator
RSC2_03095	COG3394	polysaccharide catabolic process
RSC2_03098	COG3591	Belongs to the peptidase S1B family
RSC2_03099	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_03101	COG1595	DNA-templated transcription, initiation
RSC2_03103	COG3773	Cell wall hydrolase
RSC2_03104	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RSC2_03105	COG3883	PFAM NLP P60 protein
RSC2_03105	COG0791	NLP P60 protein
RSC2_03107	COG1131	(ABC) transporter
RSC2_03108	COG1309	transcriptional regulator
RSC2_03112	COG2310	stress, protein
RSC2_03113	COG2310	stress, protein
RSC2_03114	COG2310	stress, protein
RSC2_03115	COG0861	Integral membrane protein TerC family
RSC2_03119	COG3853	Toxic anion resistance protein (TelA)
RSC2_03120	COG0785	Cytochrome C biogenesis protein
RSC2_03122	COG2223	nitrite transmembrane transporter activity
RSC2_03123	COG0039	L-malate dehydrogenase activity
RSC2_03124	COG1620	l-lactate permease
RSC2_03125	COG1280	lysine exporter protein (LysE YggA)
RSC2_03126	COG1113	amino acid transport
RSC2_03127	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RSC2_03128	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RSC2_03129	COG3541	Predicted nucleotidyltransferase
RSC2_03130	COG0506	proline dehydrogenase activity
RSC2_03131	COG1012	belongs to the aldehyde dehydrogenase family
RSC2_03132	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC2_03133	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC2_03134	COG2508	Transcriptional regulator
RSC2_03135	COG3689	TIGRFAM TIGR03943 family protein
RSC2_03136	COG0701	Predicted permease
RSC2_03137	COG3458	cephalosporin-C deacetylase activity
RSC2_03141	COG0765	amino acid transport
RSC2_03142	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RSC2_03143	COG2249	NAD(P)H dehydrogenase (quinone) activity
RSC2_03144	COG1116	anion transmembrane transporter activity
RSC2_03145	COG2723	6-phospho-beta-galactosidase activity
RSC2_03147	COG3209	COG3209 Rhs family protein
RSC2_03150	COG5444	nuclease activity
RSC2_03156	COG1177	transmembrane transport
RSC2_03157	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC2_03158	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC2_03159	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC2_03160	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
RSC2_03161	COG0697	spore germination
RSC2_03162	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC2_03164	COG2819	hydrolase of the alpha beta superfamily
RSC2_03165	COG2207	Transcriptional regulator
RSC2_03165	COG3708	Transcriptional regulator
RSC2_03167	COG2364	Membrane
RSC2_03173	COG1126	abc transporter atp-binding protein
RSC2_03174	COG0765	amino acid transport
RSC2_03175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RSC2_03176	COG3829	transcription factor binding
RSC2_03177	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RSC2_03178	COG0833	amino acid
RSC2_03179	COG0010	Belongs to the arginase family
RSC2_03180	COG0583	DNA-binding transcription factor activity
RSC2_03181	COG0163	prenyltransferase activity
RSC2_03182	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RSC2_03192	COG5444	nuclease activity
RSC2_03196	COG2972	Histidine kinase
RSC2_03197	COG4753	response regulator
RSC2_03197	COG2207	Transcriptional regulator
RSC2_03198	COG4213	ABC transporter substrate-binding protein
RSC2_03200	COG4214	carbohydrate transport
RSC2_03201	COG2271	Major facilitator Superfamily
RSC2_03202	COG0456	acetyltransferase
RSC2_03202	COG1846	Transcriptional regulator
RSC2_03203	COG1874	Beta-galactosidase
RSC2_03205	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
RSC2_03208	COG3104	oligopeptide transport
RSC2_03209	COG5434	Belongs to the glycosyl hydrolase 28 family
RSC2_03211	COG0697	spore germination
RSC2_03213	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RSC2_03214	COG0789	Transcriptional regulator
RSC2_03215	COG1136	(ABC) transporter
RSC2_03216	COG0577	efflux transmembrane transporter activity
RSC2_03217	COG0745	RESPONSE REGULATOR receiver
RSC2_03218	COG5002	protein histidine kinase activity
RSC2_03218	COG3850	Histidine kinase
RSC2_03219	COG0840	transmembrane signaling receptor activity
RSC2_03220	COG0527	aspartate kinase activity
RSC2_03222	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC2_03223	COG4605	iron ion homeostasis
RSC2_03224	COG4604	ABC transporter, ATP-binding protein
RSC2_03225	COG4607	ABC-type enterochelin transport system periplasmic component
RSC2_03226	COG2814	Major facilitator Superfamily
RSC2_03227	COG1309	transcriptional regulator
RSC2_03229	COG0778	Nitroreductase
RSC2_03230	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RSC2_03232	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC2_03233	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RSC2_03234	COG0531	amino acid
RSC2_03235	COG0531	amino acid
RSC2_03236	COG1012	belongs to the aldehyde dehydrogenase family
RSC2_03237	COG0697	spore germination
RSC2_03239	COG4549	nuclear export factor GLE1
RSC2_03240	COG2372	response to copper ion
RSC2_03240	COG1276	copper resistance
RSC2_03241	COG1349	DNA-binding transcription factor activity
RSC2_03242	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RSC2_03243	COG0243	molybdopterin cofactor binding
RSC2_03244	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RSC2_03245	COG2146	nitrite reductase [NAD(P)H] activity
RSC2_03246	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RSC2_03246	COG1587	Uroporphyrinogen-III synthase
RSC2_03247	COG1802	Transcriptional regulator
RSC2_03249	COG0471	metal ion transport
RSC2_03250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RSC2_03252	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC2_03255	COG3959	Transketolase, thiamine diphosphate binding domain
RSC2_03256	COG3958	Transketolase
RSC2_03257	COG0561	phosphatase activity
RSC2_03258	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RSC2_03259	COG1914	H( )-stimulated, divalent metal cation uptake system
RSC2_03260	COG4336	lyase activity
RSC2_03261	COG4336	lyase activity
RSC2_03262	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RSC2_03263	COG1984	allophanate hydrolase subunit 2
RSC2_03264	COG1414	Transcriptional regulator
RSC2_03265	COG2755	lipolytic protein G-D-S-L family
RSC2_03266	COG2213	PTS system mannitol-specific
RSC2_03267	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC2_03268	COG0246	Mannitol dehydrogenase
RSC2_03269	COG3711	transcriptional antiterminator
RSC2_03270	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_03271	COG1917	Cupin 2, conserved barrel domain protein
RSC2_03273	COG3871	stress protein (general stress protein 26)
RSC2_03276	COG2814	Major facilitator Superfamily
RSC2_03278	COG1522	sequence-specific DNA binding
RSC2_03279	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RSC2_03279	COG0551	DNA topoisomerase type I activity
RSC2_03280	COG0287	Prephenate dehydrogenase
RSC2_03281	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RSC2_03281	COG0512	Glutamine amidotransferase of anthranilate synthase
RSC2_03282	COG1605	Chorismate mutase
RSC2_03283	COG0028	Belongs to the TPP enzyme family
RSC2_03284	COG3397	chitin binding
RSC2_03286	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RSC2_03287	COG1914	H( )-stimulated, divalent metal cation uptake system
RSC2_03288	COG2261	transglycosylase associated protein
RSC2_03289	COG1027	Aspartate ammonia-lyase
RSC2_03290	COG1819	glycosyl
RSC2_03291	COG4876	unkown
RSC2_03292	COG2217	Heavy metal translocating P-type atpase
RSC2_03294	COG0662	Cupin 2, conserved barrel domain protein
RSC2_03296	COG0628	permease
RSC2_03297	COG1301	dicarboxylic acid transport
RSC2_03298	COG1131	(ABC) transporter
RSC2_03299	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RSC2_03301	COG1960	acyl-CoA dehydrogenase activity
RSC2_03304	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC2_03305	COG1181	Belongs to the D-alanine--D-alanine ligase family
RSC2_03306	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RSC2_03308	COG0513	Belongs to the DEAD box helicase family
RSC2_03309	COG3402	PFAM membrane-flanked domain
RSC2_03310	COG3428	Bacterial PH domain
RSC2_03311	COG0705	Rhomboid family
RSC2_03312	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RSC2_03313	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RSC2_03314	COG0864	Transcriptional regulator
RSC2_03315	COG2337	Toxic component of a toxin-antitoxin (TA) module
RSC2_03316	COG1366	Belongs to the anti-sigma-factor antagonist family
RSC2_03317	COG1366	Belongs to the anti-sigma-factor antagonist family
RSC2_03318	COG2172	sigma factor antagonist activity
RSC2_03319	COG2208	phosphoserine phosphatase activity
RSC2_03322	COG1191	sigma factor activity
RSC2_03323	COG2208	phosphoserine phosphatase activity
RSC2_03324	COG2183	response to ionizing radiation
RSC2_03325	COG1309	transcriptional regulator
RSC2_03327	COG1033	growth of symbiont in host cell
RSC2_03327	COG2409	Drug exporters of the RND superfamily
RSC2_03328	COG3091	SprT-like family
RSC2_03331	COG0640	Transcriptional regulator
RSC2_03332	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RSC2_03333	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RSC2_03334	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RSC2_03335	COG0726	polysaccharide deacetylase
RSC2_03336	COG3239	Fatty acid desaturase
RSC2_03337	COG1278	Cold shock
RSC2_03340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC2_03341	COG0477	Major facilitator Superfamily
RSC2_03343	COG2364	Membrane
RSC2_03344	COG1846	Transcriptional regulator
RSC2_03345	COG0456	acetyltransferase
RSC2_03346	COG2808	Putative FMN-binding domain
RSC2_03348	COG1733	regulation of RNA biosynthetic process
RSC2_03349	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC2_03352	COG3545	Serine hydrolase
RSC2_03353	COG1733	regulation of RNA biosynthetic process
RSC2_03356	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
RSC2_03358	COG1113	amino acid transport
RSC2_03359	COG1113	amino acid transport
RSC2_03362	COG0596	Alpha beta hydrolase
RSC2_03363	COG5566	PFAM Mor transcription activator
RSC2_03365	COG1595	DNA-templated transcription, initiation
RSC2_03367	COG2755	lipolytic protein G-D-S-L family
RSC2_03367	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RSC2_03368	COG0494	nUDIX hydrolase
RSC2_03369	COG2814	Major facilitator Superfamily
RSC2_03370	COG1979	alcohol dehydrogenase
RSC2_03371	COG0745	RESPONSE REGULATOR receiver
RSC2_03371	COG2972	Histidine kinase
RSC2_03372	COG3279	Response regulator of the LytR AlgR family
RSC2_03374	COG3764	Sortase (surface protein transpeptidase)
RSC2_03375	COG2814	Major facilitator Superfamily
RSC2_03381	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RSC2_03382	COG0802	atpase or kinase
RSC2_03383	COG1214	PFAM Peptidase M22, glycoprotease
RSC2_03384	COG0456	acetyltransferase
RSC2_03385	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RSC2_03386	COG0488	(ABC) transporter
RSC2_03388	COG0315	cyclic pyranopterin monophosphate synthase activity
RSC2_03389	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
RSC2_03390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RSC2_03391	COG0805	protein transport
RSC2_03393	COG1266	CAAX protease self-immunity
RSC2_03394	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RSC2_03395	COG0459	protein refolding
RSC2_03400	COG2720	vancomycin resistance protein
RSC2_03404	COG2135	peptidase activity
RSC2_03406	COG1309	transcriptional regulator
RSC2_03408	COG0574	Belongs to the PEP-utilizing enzyme family
RSC2_03408	COG3848	Pyruvate phosphate dikinase
RSC2_03409	COG3848	Pyruvate phosphate dikinase
RSC2_03409	COG0574	Belongs to the PEP-utilizing enzyme family
RSC2_03411	COG3189	MarR family transcriptional regulator
RSC2_03412	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
RSC2_03413	COG2272	Belongs to the type-B carboxylesterase lipase family
RSC2_03414	COG2814	Major facilitator Superfamily
RSC2_03415	COG1842	Phage shock protein A
RSC2_03416	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RSC2_03417	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RSC2_03418	COG4260	virion core protein, lumpy skin disease virus
RSC2_03420	COG1378	Sugar-specific transcriptional regulator TrmB
RSC2_03421	COG1280	lysine exporter protein (LysE YggA)
RSC2_03422	COG3339	Conserved Protein
RSC2_03423	COG0772	Belongs to the SEDS family
RSC2_03424	COG0772	Belongs to the SEDS family
RSC2_03430	COG0726	polysaccharide deacetylase
RSC2_03432	COG1609	Transcriptional regulator
RSC2_03433	COG0366	Alpha amylase catalytic
RSC2_03434	COG0366	Alpha amylase catalytic
RSC2_03435	COG2182	Extracellular solute-binding protein
RSC2_03436	COG1175	transmembrane transport
RSC2_03437	COG3833	ABC-type maltose transport systems, permease component
RSC2_03438	COG5521	maltodextrose utilization protein MalA
RSC2_03439	COG1554	hydrolase, family 65, central catalytic
RSC2_03440	COG0366	Alpha amylase catalytic
RSC2_03441	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RSC2_03442	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RSC2_03443	COG1846	Transcriptional regulator
RSC2_03446	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RSC2_03447	COG0823	Involved in the tonB-independent uptake of proteins
RSC2_03452	COG0702	epimerase
RSC2_03454	COG2132	Multicopper oxidase
RSC2_03458	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RSC2_03459	COG0714	Associated with various cellular activities
RSC2_03460	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
RSC2_03461	COG1305	Transglutaminase-like
RSC2_03462	COG0519	Catalyzes the synthesis of GMP from XMP
RSC2_03462	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RSC2_03464	COG2252	PERMEase
RSC2_03467	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
RSC2_03469	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RSC2_03470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RSC2_03471	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RSC2_03472	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RSC2_03473	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RSC2_03474	COG0047	phosphoribosylformylglycinamidine synthase activity
RSC2_03475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RSC2_03476	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RSC2_03477	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RSC2_03478	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RSC2_03479	COG0138	bifunctional purine biosynthesis protein purh
RSC2_03480	COG0151	Belongs to the GarS family
RSC2_03482	COG2124	cytochrome p450
RSC2_03488	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RSC2_03489	COG1470	cell adhesion involved in biofilm formation
RSC2_03490	COG4496	protein, YerC YecD
RSC2_03491	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
RSC2_03492	COG0210	DNA helicase
RSC2_03493	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RSC2_03494	COG4851	CamS sex pheromone cAM373 precursor
RSC2_03495	COG2188	Transcriptional regulator
RSC2_03499	COG1735	metal-dependent hydrolase with the TIM-barrel fold
RSC2_03500	COG0626	cystathionine gamma-synthase activity
RSC2_03501	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RSC2_03502	COG3457	Alanine racemase
RSC2_03503	COG0363	glucosamine-6-phosphate deaminase activity
RSC2_03504	COG1285	pathogenesis
RSC2_03505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC2_03506	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RSC2_03507	COG0154	amidase activity
RSC2_03508	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RSC2_03511	COG4124	Belongs to the glycosyl hydrolase 26 family
RSC2_03512	COG1309	transcriptional regulator
RSC2_03513	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RSC2_03515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RSC2_03516	COG1957	nucleoside hydrolase
RSC2_03517	COG1597	lipid kinase activity
RSC2_03518	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RSC2_03525	COG2723	6-phospho-beta-galactosidase activity
RSC2_03526	COG3711	transcriptional antiterminator
RSC2_03527	COG0457	Tetratricopeptide repeat
RSC2_03530	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
RSC2_03530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RSC2_03531	COG3586	endonuclease activity
RSC2_03532	COG0697	spore germination
RSC2_03533	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC2_03534	COG0697	spore germination
RSC2_03535	COG0217	transcriptional regulatory protein
RSC2_03541	COG1012	belongs to the aldehyde dehydrogenase family
RSC2_03542	COG0840	transmembrane signaling receptor activity
RSC2_03543	COG0109	protoheme IX farnesyltransferase activity
RSC2_03544	COG1309	transcriptional regulator
RSC2_03545	COG0471	metal ion transport
RSC2_03546	COG0488	(ABC) transporter
RSC2_03547	COG0583	DNA-binding transcription factor activity
RSC2_03549	COG1469	GTP cyclohydrolase I activity
RSC2_03553	COG0523	cobalamin synthesis protein
RSC2_03554	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
RSC2_03555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RSC2_03556	COG0156	8-amino-7-oxononanoate synthase activity
RSC2_03557	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RSC2_03558	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RSC2_03559	COG2124	cytochrome p450
RSC2_03561	COG0789	Transcriptional regulator
RSC2_03562	COG2814	Major facilitator Superfamily
RSC2_03563	COG0488	(ABC) transporter
RSC2_03564	COG0513	Belongs to the DEAD box helicase family
RSC2_03565	COG2130	NADP-dependent
RSC2_03568	COG0471	metal ion transport
RSC2_03570	COG1136	(ABC) transporter
RSC2_03574	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC2_03576	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
RSC2_03577	COG3858	chitin binding
RSC2_03578	COG5658	integral membrane protein
RSC2_03579	COG0640	Transcriptional regulator
RSC2_03580	COG1254	Belongs to the acylphosphatase family
RSC2_03581	COG2258	MOSC domain
RSC2_03584	COG0024	Methionine aminopeptidase
RSC2_03585	COG1368	sulfuric ester hydrolase activity
RSC2_03587	COG1115	amino acid carrier protein
RSC2_03588	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_03588	COG1263	PTS System
RSC2_03589	COG0366	Alpha amylase catalytic
RSC2_03590	COG2188	Transcriptional regulator
RSC2_03595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RSC2_03596	COG1045	serine acetyltransferase
RSC2_03597	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RSC2_03599	COG1215	transferase activity, transferring glycosyl groups
RSC2_03600	COG0457	Tetratricopeptide repeat
RSC2_03600	COG0463	Glycosyl transferase, family 2
RSC2_03602	COG0673	inositol 2-dehydrogenase activity
RSC2_03605	COG1733	regulation of RNA biosynthetic process
RSC2_03606	COG0778	Nitroreductase
RSC2_03607	COG0737	Belongs to the 5'-nucleotidase family
RSC2_03608	COG0693	protein deglycase activity
RSC2_03609	COG4840	Belongs to the UPF0435 family
RSC2_03610	COG1115	amino acid carrier protein
RSC2_03611	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RSC2_03612	COG4980	gas vesicle protein
RSC2_03613	COG1295	ribonuclease BN
RSC2_03615	COG0477	Major facilitator Superfamily
RSC2_03617	COG0387	Pfam Sodium calcium exchanger
RSC2_03619	COG0535	radical SAM domain protein
RSC2_03622	COG0726	polysaccharide deacetylase
RSC2_03623	COG0371	Dehydrogenase
RSC2_03625	COG0598	Magnesium transport protein CorA
RSC2_03626	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
RSC2_03627	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RSC2_03628	COG4637	Psort location Cytoplasmic, score
RSC2_03633	COG1819	glycosyl
RSC2_03635	COG0477	Major facilitator Superfamily
RSC2_03637	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_03637	COG1263	PTS System
RSC2_03638	COG3711	transcriptional antiterminator
RSC2_03639	COG0288	reversible hydration of carbon dioxide
RSC2_03640	COG3002	Belongs to the UPF0753 family
RSC2_03641	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RSC2_03642	COG5609	conserved protein (DUF2294)
RSC2_03644	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RSC2_03645	COG0022	dehydrogenase e1 component
RSC2_03646	COG0508	dehydrogenase complex catalyzes the overall conversion of
RSC2_03647	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RSC2_03648	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RSC2_03649	COG3284	Transcriptional regulator
RSC2_03650	COG1742	UPF0060 membrane protein
RSC2_03651	COG1486	melibiose metabolic process
RSC2_03652	COG1737	Transcriptional regulator
RSC2_03653	COG1263	PTS System
RSC2_03653	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_03657	COG1733	regulation of RNA biosynthetic process
RSC2_03658	COG2259	Doxx family
RSC2_03659	COG2514	catechol 2,3-dioxygenase activity
RSC2_03661	COG3507	Belongs to the glycosyl hydrolase 43 family
RSC2_03662	COG1917	Cupin 2, conserved barrel domain protein
RSC2_03662	COG2207	Transcriptional regulator
RSC2_03663	COG1653	transport
RSC2_03664	COG2249	NAD(P)H dehydrogenase (quinone) activity
RSC2_03665	COG1051	belongs to the nudix hydrolase family
RSC2_03667	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RSC2_03667	COG0392	lysyltransferase activity
RSC2_03668	COG0384	phenazine biosynthesis protein PhzF
RSC2_03669	COG0778	Nitroreductase
RSC2_03672	COG1090	epimerase
RSC2_03673	COG2137	regulation of response to DNA damage stimulus
RSC2_03679	COG0463	Glycosyl transferase, family 2
RSC2_03681	COG4485	Bacterial membrane protein, YfhO
RSC2_03682	COG1988	membrane-bound metal-dependent
RSC2_03683	COG1194	a g-specific adenine glycosylase
RSC2_03685	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_03688	COG3557	Belongs to the UPF0374 family
RSC2_03689	COG1132	(ABC) transporter
RSC2_03690	COG0444	Belongs to the ABC transporter superfamily
RSC2_03691	COG4608	Belongs to the ABC transporter superfamily
RSC2_03692	COG0747	negative chemotaxis
RSC2_03693	COG0601	transmembrane transport
RSC2_03694	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSC2_03695	COG4129	membrane
RSC2_03696	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RSC2_03697	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RSC2_03698	COG0735	belongs to the Fur family
RSC2_03710	COG0457	Tetratricopeptide repeat
RSC2_03715	COG5444	nuclease activity
RSC2_03718	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RSC2_03724	COG0710	3-dehydroquinate dehydratase activity
RSC2_03725	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RSC2_03726	COG1116	anion transmembrane transporter activity
RSC2_03727	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RSC2_03728	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RSC2_03729	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RSC2_03731	COG1476	TRANSCRIPTIONal
RSC2_03733	COG1131	(ABC) transporter
RSC2_03737	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RSC2_03739	COG3382	B3 4 domain protein
RSC2_03740	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RSC2_03742	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RSC2_03743	COG0789	Transcriptional regulator
RSC2_03744	COG1664	Polymer-forming cytoskeletal
RSC2_03745	COG1664	Polymer-forming cytoskeletal
RSC2_03748	COG2766	serine protein kinase
RSC2_03749	COG2718	Belongs to the UPF0229 family
RSC2_03750	COG1566	PFAM secretion protein HlyD family protein
RSC2_03751	COG2814	Major facilitator Superfamily
RSC2_03752	COG0655	NAD(P)H dehydrogenase (quinone) activity
RSC2_03755	COG1725	Transcriptional regulator
RSC2_03756	COG1131	(ABC) transporter
RSC2_03757	COG1131	(ABC) transporter
RSC2_03758	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RSC2_03759	COG1278	Cold shock
RSC2_03761	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RSC2_03762	COG2011	ABC-type metal ion transport system permease component
RSC2_03763	COG1464	Belongs to the NlpA lipoprotein family
RSC2_03764	COG1823	symporter activity
RSC2_03770	COG5577	PFAM Coat F domain
RSC2_03771	COG5002	protein histidine kinase activity
RSC2_03772	COG0737	Belongs to the 5'-nucleotidase family
RSC2_03772	COG4085	toxin activity
RSC2_03772	COG1525	nuclease
RSC2_03773	COG0737	Belongs to the 5'-nucleotidase family
RSC2_03773	COG1525	nuclease
RSC2_03773	COG4085	toxin activity
RSC2_03774	COG3764	Sortase (surface protein transpeptidase)
RSC2_03775	COG0564	pseudouridine synthase activity
RSC2_03777	COG0517	IMP dehydrogenase activity
RSC2_03778	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RSC2_03779	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RSC2_03779	COG3153	acetyltransferase
RSC2_03781	COG0488	(ABC) transporter
RSC2_03782	COG2116	formate transmembrane transporter activity
RSC2_03785	COG0604	alcohol dehydrogenase
RSC2_03786	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RSC2_03787	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RSC2_03788	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RSC2_03789	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RSC2_03790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RSC2_03793	COG4585	Histidine kinase
RSC2_03793	COG2203	Gaf domain
RSC2_03794	COG2197	response regulator
RSC2_03795	COG0431	NADPH-dependent FMN reductase
RSC2_03798	COG1959	2 iron, 2 sulfur cluster binding
RSC2_03799	COG1017	nitric oxide dioxygenase activity
RSC2_03799	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RSC2_03800	COG2719	SpoVR family
RSC2_03801	COG2719	SpoVR family
RSC2_03802	COG0791	NLP P60 protein
RSC2_03802	COG1388	LysM domain
RSC2_03803	COG0583	DNA-binding transcription factor activity
RSC2_03804	COG0372	Belongs to the citrate synthase family
RSC2_03805	COG0372	Belongs to the citrate synthase family
RSC2_03806	COG2133	pyrroloquinoline quinone binding
RSC2_03807	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_03808	COG0733	neurotransmitter:sodium symporter activity
RSC2_03812	COG5444	nuclease activity
RSC2_03813	COG3708	Transcriptional regulator
RSC2_03813	COG2207	Transcriptional regulator
RSC2_03814	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC2_03818	COG1595	DNA-templated transcription, initiation
RSC2_03819	COG0662	Cupin 2, conserved barrel domain protein
RSC2_03821	COG0667	Aldo Keto reductase
RSC2_03822	COG0204	Acyl-transferase
RSC2_03823	COG3152	Membrane
RSC2_03825	COG1309	transcriptional regulator
RSC2_03826	COG1253	flavin adenine dinucleotide binding
RSC2_03827	COG0789	Transcriptional regulator
RSC2_03829	COG1253	flavin adenine dinucleotide binding
RSC2_03833	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RSC2_03834	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RSC2_03835	COG0584	glycerophosphoryl diester phosphodiesterase
RSC2_03837	COG0668	transmembrane transport
RSC2_03838	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RSC2_03840	COG0726	polysaccharide deacetylase
RSC2_03843	COG1757	Na H antiporter
RSC2_03844	COG2017	converts alpha-aldose to the beta-anomer
RSC2_03849	COG0589	response to stress
RSC2_03851	COG1132	(ABC) transporter
RSC2_03852	COG1132	(ABC) transporter
RSC2_03853	COG1132	(ABC) transporter
RSC2_03854	COG0702	epimerase
RSC2_03858	COG3842	ATPase activity
RSC2_03859	COG2508	Transcriptional regulator
RSC2_03861	COG0189	ligase activity
RSC2_03862	COG0189	ligase activity
RSC2_03863	COG4399	Belongs to the UPF0754 family
RSC2_03864	COG3679	Belongs to the UPF0342 family
RSC2_03865	COG0561	phosphatase activity
RSC2_03866	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RSC2_03867	COG0475	glutathione-regulated potassium exporter activity
RSC2_03868	COG0490	domain, Protein
RSC2_03870	COG1024	Enoyl-CoA hydratase
RSC2_03872	COG0457	Tetratricopeptide repeat
RSC2_03876	COG4152	abc transporter atp-binding protein
RSC2_03877	COG1668	transmembrane transport
RSC2_03878	COG0420	3'-5' exonuclease activity
RSC2_03879	COG4717	serine-type aminopeptidase activity
RSC2_03880	COG3481	metal-dependent phosphohydrolase, HD sub domain
RSC2_03882	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RSC2_03888	COG1846	Transcriptional regulator
RSC2_03889	COG4980	gas vesicle protein
RSC2_03892	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RSC2_03893	COG0537	adenosine 5'-monophosphoramidase activity
RSC2_03894	COG1131	(ABC) transporter
RSC2_03895	COG4473	ABC transporter
RSC2_03897	COG1473	amidohydrolase
RSC2_03898	COG3069	C4-dicarboxylate transmembrane transporter activity
RSC2_03899	COG2329	Antibiotic biosynthesis monooxygenase
RSC2_03900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RSC2_03901	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RSC2_03902	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RSC2_03903	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
RSC2_03904	COG1309	transcriptional regulator
RSC2_03905	COG1511	domain protein
RSC2_03906	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RSC2_03907	COG1363	Peptidase, m42
RSC2_03909	COG1301	dicarboxylic acid transport
RSC2_03910	COG1234	tRNA 3'-trailer cleavage
RSC2_03911	COG0095	Lipoate-protein ligase
RSC2_03912	COG0318	PFAM AMP-dependent synthetase and ligase
RSC2_03913	COG1396	sequence-specific DNA binding
RSC2_03916	COG0501	Belongs to the peptidase M48B family
RSC2_03919	COG0697	spore germination
RSC2_03920	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RSC2_03921	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC2_03922	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC2_03923	COG0406	alpha-ribazole phosphatase activity
RSC2_03924	COG0840	transmembrane signaling receptor activity
RSC2_03925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RSC2_03925	COG0723	plastoquinol--plastocyanin reductase activity
RSC2_03926	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_03928	COG4903	ComK protein
RSC2_03930	COG0398	Pfam SNARE associated Golgi protein
RSC2_03931	COG0681	Belongs to the peptidase S26 family
RSC2_03933	COG1404	Belongs to the peptidase S8 family
RSC2_03935	COG2508	Transcriptional regulator
RSC2_03937	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RSC2_03938	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RSC2_03939	COG3257	ureidoglycine aminohydrolase activity
RSC2_03940	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RSC2_03941	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RSC2_03942	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RSC2_03943	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RSC2_03945	COG0549	Belongs to the carbamate kinase family
RSC2_03946	COG2814	Major facilitator Superfamily
RSC2_03947	COG0457	Tetratricopeptide repeat
RSC2_03949	COG1609	Transcriptional regulator
RSC2_03950	COG1653	transport
RSC2_03951	COG1175	transmembrane transport
RSC2_03952	COG0395	ABC-type sugar transport system, permease component
RSC2_03953	COG1486	melibiose metabolic process
RSC2_03954	COG3180	Ammonia monooxygenase
RSC2_03957	COG3546	catalase activity
RSC2_03958	COG0318	PFAM AMP-dependent synthetase and ligase
RSC2_03959	COG0477	Major facilitator Superfamily
RSC2_03959	COG2814	Major facilitator Superfamily
RSC2_03960	COG4533	DNA binding
RSC2_03963	COG5002	protein histidine kinase activity
RSC2_03964	COG0745	RESPONSE REGULATOR receiver
RSC2_03965	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
RSC2_03966	COG0725	ABC transporter, periplasmic molybdate-binding protein
RSC2_03967	COG4149	molybdate abc transporter
RSC2_03968	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
RSC2_03969	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
RSC2_03970	COG1074	ATP-dependent DNA helicase activity
RSC2_03971	COG1074	ATP-dependent DNA helicase activity
RSC2_03972	COG0420	3'-5' exonuclease activity
RSC2_03973	COG0419	ATPase involved in DNA repair
RSC2_03982	COG5337	Spore coat protein CotH
RSC2_03983	COG5337	Spore coat protein CotH
RSC2_03985	COG0179	Fumarylacetoacetate (FAA) hydrolase
RSC2_03990	COG0367	asparagine synthase
RSC2_03991	COG0004	ammonium transporteR
RSC2_03992	COG0347	Belongs to the P(II) protein family
RSC2_03993	COG0534	Mate efflux family protein
RSC2_03994	COG2207	Transcriptional regulator
RSC2_03994	COG1917	Cupin 2, conserved barrel domain protein
RSC2_03996	COG1609	Transcriptional regulator
RSC2_03997	COG0673	inositol 2-dehydrogenase activity
RSC2_04001	COG0697	spore germination
RSC2_04002	COG1279	arginine transmembrane transporter activity
RSC2_04003	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC2_04005	COG0076	glutamate decarboxylase activity
RSC2_04011	COG2153	protein acetylation
RSC2_04012	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_04013	COG2378	regulation of single-species biofilm formation
RSC2_04014	COG0646	methionine synthase
RSC2_04014	COG1410	methionine synthase
RSC2_04015	COG0646	methionine synthase
RSC2_04015	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RSC2_04016	COG1666	GTP binding
RSC2_04017	COG2996	Protein conserved in bacteria
RSC2_04020	COG1307	EDD domain protein, DegV family
RSC2_04021	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC2_04023	COG0516	GMP reductase activity
RSC2_04026	COG0561	phosphatase activity
RSC2_04027	COG1073	alpha beta
RSC2_04028	COG2151	metal-sulfur cluster biosynthetic enzyme
RSC2_04029	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RSC2_04030	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RSC2_04031	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RSC2_04032	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RSC2_04033	COG0505	Belongs to the CarA family
RSC2_04034	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RSC2_04035	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RSC2_04036	COG1968	undecaprenyl-diphosphatase activity
RSC2_04039	COG2267	carboxylic ester hydrolase activity
RSC2_04041	COG1744	ABC transporter substrate-binding protein PnrA-like
RSC2_04044	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RSC2_04045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RSC2_04047	COG5504	Zn-dependent protease
RSC2_04048	COG0444	Belongs to the ABC transporter superfamily
RSC2_04049	COG4608	Belongs to the ABC transporter superfamily
RSC2_04051	COG0601	transmembrane transport
RSC2_04052	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSC2_04055	COG0180	Tryptophanyl-tRNA synthetase
RSC2_04057	COG4166	transmembrane transport
RSC2_04058	COG0601	transmembrane transport
RSC2_04059	COG0601	transmembrane transport
RSC2_04060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSC2_04061	COG0444	Belongs to the ABC transporter superfamily
RSC2_04062	COG4608	Belongs to the ABC transporter superfamily
RSC2_04063	COG0456	acetyltransferase
RSC2_04064	COG1393	Belongs to the ArsC family
RSC2_04065	COG0861	Integral membrane protein TerC family
RSC2_04066	COG4862	establishment of competence for transformation
RSC2_04071	COG4565	transcriptional regulatory protein
RSC2_04072	COG3290	protein histidine kinase activity
RSC2_04073	COG4469	Competence protein
RSC2_04074	COG1164	Oligoendopeptidase f
RSC2_04075	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RSC2_04076	COG2346	COG2346, Truncated hemoglobins
RSC2_04077	COG0741	lytic transglycosylase activity
RSC2_04078	COG4116	CYTH
RSC2_04080	COG2357	RelA SpoT domain protein
RSC2_04081	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RSC2_04082	COG0564	pseudouridine synthase activity
RSC2_04083	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RSC2_04084	COG0475	glutathione-regulated potassium exporter activity
RSC2_04084	COG0569	domain protein
RSC2_04085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RSC2_04086	COG0352	thiamine-phosphate diphosphorylase activity
RSC2_04088	COG2104	thiamine diphosphate biosynthetic process
RSC2_04089	COG2022	thiamine diphosphate biosynthetic process
RSC2_04090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RSC2_04091	COG0351	phosphomethylpyrimidine kinase
RSC2_04092	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RSC2_04104	COG0210	DNA helicase
RSC2_04106	COG0586	Pfam SNARE associated Golgi protein
RSC2_04107	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RSC2_04108	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RSC2_04109	COG2246	polysaccharide biosynthetic process
RSC2_04110	COG2153	protein acetylation
RSC2_04111	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RSC2_04112	COG2382	esterase
RSC2_04117	COG0626	cystathionine gamma-synthase activity
RSC2_04118	COG0626	cystathionine gamma-synthase activity
RSC2_04119	COG5505	Protein of unknown function (DUF819)
RSC2_04122	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RSC2_04123	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RSC2_04125	COG3507	Belongs to the glycosyl hydrolase 43 family
RSC2_04128	COG0110	maltose O-acetyltransferase activity
RSC2_04130	COG0583	DNA-binding transcription factor activity
RSC2_04131	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RSC2_04132	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RSC2_04133	COG0583	DNA-binding transcription factor activity
RSC2_04134	COG0697	spore germination
RSC2_04135	COG0346	lactoylglutathione lyase activity
RSC2_04137	COG3584	3D domain protein
RSC2_04137	COG1388	LysM domain
RSC2_04138	COG2814	Major facilitator Superfamily
RSC2_04139	COG1309	transcriptional regulator
RSC2_04143	COG5444	nuclease activity
RSC2_04144	COG4195	phage-related replication protein
RSC2_04145	COG2856	Zn peptidase
RSC2_04146	COG1396	sequence-specific DNA binding
RSC2_04149	COG1522	sequence-specific DNA binding
RSC2_04150	COG1484	DNA-dependent DNA replication
RSC2_04155	COG1595	DNA-templated transcription, initiation
RSC2_04156	COG3728	DNA packaging
RSC2_04156	COG5484	DNA packaging
RSC2_04157	COG1783	phage Terminase large subunit
RSC2_04158	COG5518	Phage portal protein
RSC2_04159	COG0338	D12 class N6 adenine-specific DNA methyltransferase
RSC2_04160	COG4653	Phage capsid family
RSC2_04171	COG5280	Phage tail tape measure protein TP901
RSC2_04171	COG3953	SLT domain
RSC2_04172	COG1652	LysM domain
RSC2_04173	COG4193	domain, Protein
RSC2_04175	COG3628	GPW Gp25 family protein
RSC2_04176	COG3299	homolog of phage Mu protein gp47
RSC2_04177	COG3778	Protein conserved in bacteria
RSC2_04184	COG1802	Transcriptional regulator
RSC2_04185	COG1063	alcohol dehydrogenase
RSC2_04186	COG1312	Catalyzes the dehydration of D-mannonate
RSC2_04187	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_04188	COG1063	alcohol dehydrogenase
RSC2_04189	COG2271	Major facilitator Superfamily
RSC2_04192	COG0306	phosphate transporter
RSC2_04193	COG1392	Phosphate transport regulator
RSC2_04194	COG0405	Gamma-glutamyltransferase
RSC2_04195	COG5578	integral membrane protein
RSC2_04196	COG2972	Histidine kinase
RSC2_04197	COG2972	Histidine kinase
RSC2_04198	COG4753	response regulator
RSC2_04198	COG2207	Transcriptional regulator
RSC2_04199	COG1653	transport
RSC2_04200	COG1175	transmembrane transport
RSC2_04201	COG0395	ABC-type sugar transport system, permease component
RSC2_04202	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RSC2_04203	COG2207	Transcriptional regulator
RSC2_04204	COG2755	lipolytic protein G-D-S-L family
RSC2_04206	COG5578	integral membrane protein
RSC2_04207	COG3401	FG-GAP repeat protein
RSC2_04208	COG2755	lipolytic protein G-D-S-L family
RSC2_04209	COG3401	FG-GAP repeat protein
RSC2_04210	COG0667	Aldo Keto reductase
RSC2_04211	COG0667	Aldo Keto reductase
RSC2_04212	COG2755	lipolytic protein G-D-S-L family
RSC2_04213	COG1874	Beta-galactosidase
RSC2_04215	COG1653	transport
RSC2_04216	COG4209	transmembrane transport
RSC2_04217	COG0395	ABC-type sugar transport system, permease component
RSC2_04218	COG0531	amino acid
RSC2_04219	COG0346	lactoylglutathione lyase activity
RSC2_04220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RSC2_04221	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RSC2_04222	COG2362	D-Aminopeptidase
RSC2_04223	COG0601	transmembrane transport
RSC2_04224	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSC2_04225	COG0444	Belongs to the ABC transporter superfamily
RSC2_04226	COG4166	transmembrane transport
RSC2_04227	COG1619	proteins homologs of microcin C7 resistance protein MccF
RSC2_04228	COG4948	Mandelate Racemase Muconate Lactonizing
RSC2_04229	COG0791	NLP P60 protein
RSC2_04230	COG4608	Belongs to the ABC transporter superfamily
RSC2_04232	COG1834	amidinotransferase
RSC2_04233	COG1607	acyl-coa hydrolase
RSC2_04234	COG2323	membrane
RSC2_04235	COG3866	Pectate lyase
RSC2_04239	COG2318	DinB family
RSC2_04240	COG2076	Multidrug Resistance protein
RSC2_04241	COG2076	Multidrug Resistance protein
RSC2_04242	COG0788	formyltetrahydrofolate deformylase activity
RSC2_04243	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RSC2_04244	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RSC2_04245	COG1764	response to oxidative stress
RSC2_04246	COG1846	Transcriptional regulator
RSC2_04247	COG1764	response to oxidative stress
RSC2_04249	COG0590	tRNA wobble adenosine to inosine editing
RSC2_04250	COG0406	alpha-ribazole phosphatase activity
RSC2_04253	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RSC2_04254	COG1404	Belongs to the peptidase S8 family
RSC2_04256	COG2239	Acts as a magnesium transporter
RSC2_04258	COG0789	Transcriptional regulator
RSC2_04260	COG1846	Transcriptional regulator
RSC2_04261	COG1793	dna ligase
RSC2_04261	COG3285	dna ligase
RSC2_04262	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RSC2_04263	COG3300	MHYT domain
RSC2_04263	COG5001	Diguanylate cyclase
RSC2_04264	COG0586	Pfam SNARE associated Golgi protein
RSC2_04265	COG0861	Integral membrane protein TerC family
RSC2_04266	COG1191	sigma factor activity
RSC2_04270	COG0501	Belongs to the peptidase M48B family
RSC2_04271	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RSC2_04272	COG0768	penicillin binding
RSC2_04275	COG3594	Acyltransferase
RSC2_04276	COG5002	protein histidine kinase activity
RSC2_04277	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RSC2_04279	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
RSC2_04280	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
RSC2_04281	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RSC2_04282	COG0436	Aminotransferase
RSC2_04283	COG1850	ribulose-bisphosphate carboxylase activity
RSC2_04284	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
RSC2_04284	COG0235	Class ii aldolase
RSC2_04285	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
RSC2_04285	COG0235	Class ii aldolase
RSC2_04286	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
RSC2_04287	COG0346	lactoylglutathione lyase activity
RSC2_04288	COG3339	Conserved Protein
RSC2_04290	COG3852	Histidine kinase
RSC2_04291	COG1846	Transcriptional regulator
RSC2_04292	COG1360	Flagellar Motor Protein
RSC2_04293	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RSC2_04294	COG0542	response to heat
RSC2_04295	COG3949	Membrane
RSC2_04296	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RSC2_04297	COG0720	synthase
RSC2_04298	COG0602	queuosine metabolic process
RSC2_04299	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RSC2_04301	COG0457	Tetratricopeptide repeat
RSC2_04304	COG3739	integral membrane protein
RSC2_04306	COG3655	Transcriptional regulator
RSC2_04315	COG4873	Protein conserved in bacteria
RSC2_04317	COG3773	Cell wall hydrolase
RSC2_04318	COG2244	polysaccharide biosynthetic process
RSC2_04319	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC2_04320	COG2217	Heavy metal translocating P-type atpase
RSC2_04321	COG0006	proline dipeptidase activity
RSC2_04324	COG1609	Transcriptional regulator
RSC2_04325	COG3711	transcriptional antiterminator
RSC2_04326	COG1263	PTS System
RSC2_04326	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC2_04326	COG2190	(PTS) system
RSC2_04327	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC2_04328	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RSC2_04330	COG1533	DNA photolyase activity
RSC2_04331	COG0456	acetyltransferase
RSC2_04332	COG0840	transmembrane signaling receptor activity
RSC2_04333	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_04334	COG2084	Dehydrogenase
RSC2_04335	COG2340	Cysteine-rich secretory protein family
RSC2_04336	COG0768	penicillin binding
RSC2_04337	COG4191	Histidine kinase
RSC2_04338	COG0436	Aminotransferase
RSC2_04340	COG1714	RDD family
RSC2_04342	COG0784	Response regulator, receiver
RSC2_04342	COG0835	chemotaxis
RSC2_04344	COG2814	Major facilitator Superfamily
RSC2_04345	COG1376	ErfK ybiS ycfS ynhG family protein
RSC2_04346	COG1408	metallophosphoesterase
RSC2_04347	COG1028	Short-chain dehydrogenase reductase Sdr
RSC2_04348	COG2200	EAL domain
RSC2_04351	COG4703	Protein of unknown function (DUF1797)
RSC2_04352	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
RSC2_04354	COG0517	IMP dehydrogenase activity
RSC2_04355	COG0583	DNA-binding transcription factor activity
RSC2_04356	COG0716	FMN binding
RSC2_04358	COG0716	FMN binding
RSC2_04359	COG2171	N-acyltransferase activity
RSC2_04360	COG1473	amidohydrolase
RSC2_04362	COG0450	alkyl hydroperoxide reductase
RSC2_04363	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC2_04366	COG0746	molybdenum cofactor guanylyltransferase activity
RSC2_04367	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RSC2_04368	COG0303	'Molybdopterin
RSC2_04369	COG1763	Mo-molybdopterin cofactor biosynthetic process
RSC2_04370	COG0314	molybdopterin synthase activity
RSC2_04371	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
RSC2_04373	COG1132	(ABC) transporter
RSC2_04374	COG1132	(ABC) transporter
RSC2_04376	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RSC2_04377	COG1136	(ABC) transporter
RSC2_04378	COG0577	efflux transmembrane transporter activity
RSC2_04380	COG1349	DNA-binding transcription factor activity
RSC2_04381	COG1105	Belongs to the carbohydrate kinase PfkB family
RSC2_04382	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC2_04382	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSC2_04382	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSC2_04386	COG0488	(ABC) transporter
RSC2_04388	COG2309	aminopeptidase activity
RSC2_04390	COG1077	Cell shape determining protein MreB Mrl
RSC2_04391	COG2002	toxin-antitoxin pair type II binding
RSC2_04392	COG3852	Histidine kinase
RSC2_04393	COG0569	domain protein
RSC2_04394	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RSC2_04395	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RSC2_04396	COG5503	Protein of unknown function (DUF1447)
RSC2_04397	COG0561	phosphatase activity
RSC2_04398	COG0242	peptide deformylase activity
RSC2_04400	COG0497	DNA recombination
RSC2_04402	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RSC2_04403	COG0022	dehydrogenase e1 component
RSC2_04404	COG0508	dehydrogenase complex catalyzes the overall conversion of
RSC2_04405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RSC2_04406	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC2_04408	COG1982	Orn Lys Arg decarboxylase major
RSC2_04409	COG4476	Belongs to the UPF0223 family
RSC2_04410	COG4493	Belongs to the UPF0637 family
RSC2_04412	COG0483	inositol monophosphate 1-phosphatase activity
RSC2_04416	COG1595	DNA-templated transcription, initiation
RSC2_04419	COG1217	gtp-binding protein TYPA
RSC2_04421	COG1846	Transcriptional regulator
RSC2_04422	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RSC2_04423	COG4896	Protein conserved in bacteria
RSC2_04425	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RSC2_04426	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RSC2_04427	COG2066	Belongs to the glutaminase family
RSC2_04428	COG4838	Belongs to the UPF0358 family
RSC2_04429	COG0772	Belongs to the SEDS family
RSC2_04430	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RSC2_04431	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RSC2_04432	COG1612	heme a metabolic process
RSC2_04433	COG0109	protoheme IX farnesyltransferase activity
RSC2_04434	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RSC2_04434	COG2010	Cytochrome c
RSC2_04435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RSC2_04436	COG1845	cytochrome c oxidase, subunit III
RSC2_04437	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RSC2_04438	COG3336	cytochrome c oxidase
RSC2_04440	COG2905	signal-transduction protein containing cAMP-binding and CBS domains