locus-tag	class	description
RSC3_00001	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RSC3_00002	COG3688	RNA-binding protein containing a PIN domain
RSC3_00005	COG0250	Participates in transcription elongation, termination and antitermination
RSC3_00006	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RSC3_00007	COG0081	regulation of translation
RSC3_00008	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RSC3_00009	COG0222	ribosome binding
RSC3_00010	COG2813	Specifically methylates the guanine in position
RSC3_00011	COG2813	Specifically methylates the guanine in position
RSC3_00012	COG0085	RNA polymerase activity
RSC3_00013	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RSC3_00014	COG1358	cellular component organization or biogenesis
RSC3_00016	COG0049	tRNA binding
RSC3_00017	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RSC3_00018	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RSC3_00020	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RSC3_00021	COG0088	Forms part of the polypeptide exit tunnel
RSC3_00022	COG0089	rRNA binding
RSC3_00024	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RSC3_00025	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RSC3_00026	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RSC3_00027	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RSC3_00028	COG0255	Belongs to the universal ribosomal protein uL29 family
RSC3_00029	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RSC3_00030	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RSC3_00031	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RSC3_00032	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RSC3_00033	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RSC3_00034	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RSC3_00035	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RSC3_00036	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RSC3_00037	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RSC3_00038	COG1841	ribosomal large subunit assembly
RSC3_00039	COG0200	Binds to the 23S rRNA
RSC3_00040	COG0201	protein transport
RSC3_00041	COG0563	adenylate kinase activity
RSC3_00042	COG0024	Methionine aminopeptidase
RSC3_00043	COG2163	COG2163 Ribosomal protein L14E L6E L27E
RSC3_00044	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RSC3_00045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RSC3_00046	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RSC3_00047	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RSC3_00048	COG0202	RNA polymerase activity
RSC3_00049	COG0203	ribosomal protein L17
RSC3_00050	COG1122	ATPase activity
RSC3_00051	COG1122	ATPase activity
RSC3_00052	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RSC3_00053	COG0101	tRNA pseudouridine synthase activity
RSC3_00054	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RSC3_00055	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RSC3_00056	COG2318	DinB family
RSC3_00059	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSC3_00060	COG0489	protein tyrosine kinase activity
RSC3_00062	COG2194	sulfuric ester hydrolase activity
RSC3_00063	COG0726	polysaccharide deacetylase
RSC3_00068	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RSC3_00070	COG0385	Bile acid
RSC3_00073	COG3876	Protein conserved in bacteria
RSC3_00074	COG1472	Belongs to the glycosyl hydrolase 3 family
RSC3_00075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RSC3_00076	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RSC3_00077	COG1263	PTS System
RSC3_00077	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC3_00078	COG1737	Transcriptional regulator
RSC3_00079	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
RSC3_00080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
RSC3_00081	COG1683	Conserved Protein
RSC3_00083	COG1595	DNA-templated transcription, initiation
RSC3_00084	COG5662	AntiSigma factor
RSC3_00085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RSC3_00086	COG4856	YbbR-like protein
RSC3_00087	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RSC3_00088	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RSC3_00092	COG1725	Transcriptional regulator
RSC3_00094	COG0789	Transcriptional regulator
RSC3_00097	COG0640	Transcriptional regulator
RSC3_00098	COG2814	Major facilitator Superfamily
RSC3_00100	COG1132	(ABC) transporter
RSC3_00101	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RSC3_00103	COG1132	(ABC) transporter
RSC3_00104	COG2312	Erythromycin esterase
RSC3_00108	COG1011	Hydrolase
RSC3_00109	COG1113	amino acid transport
RSC3_00111	COG2851	Citrate transporter
RSC3_00112	COG3181	Tripartite tricarboxylate transporter family receptor
RSC3_00113	COG4565	transcriptional regulatory protein
RSC3_00114	COG3290	protein histidine kinase activity
RSC3_00117	COG2211	Major facilitator Superfamily
RSC3_00122	COG1331	Highly conserved protein containing a thioredoxin domain
RSC3_00125	COG0076	glutamate decarboxylase activity
RSC3_00126	COG0778	Nitroreductase
RSC3_00127	COG1802	Transcriptional regulator
RSC3_00128	COG0730	response to heat
RSC3_00132	COG1283	sodium-dependent phosphate transmembrane transporter activity
RSC3_00133	COG0704	Plays a role in the regulation of phosphate uptake
RSC3_00134	COG4682	membrane
RSC3_00139	COG0697	spore germination
RSC3_00140	COG1917	Cupin 2, conserved barrel domain protein
RSC3_00140	COG2207	Transcriptional regulator
RSC3_00143	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RSC3_00148	COG0371	Dehydrogenase
RSC3_00151	COG4257	antibiotic catabolic process
RSC3_00153	COG0833	amino acid
RSC3_00154	COG2040	homocysteine
RSC3_00156	COG1263	PTS System
RSC3_00156	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC3_00158	COG2323	membrane
RSC3_00163	COG2205	protein histidine kinase activity
RSC3_00164	COG1115	amino acid carrier protein
RSC3_00165	COG2066	Belongs to the glutaminase family
RSC3_00166	COG4191	Histidine kinase
RSC3_00167	COG0784	Response regulator, receiver
RSC3_00172	COG3540	Alkaline phosphatase
RSC3_00173	COG3540	Alkaline phosphatase
RSC3_00174	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RSC3_00175	COG0805	protein transport
RSC3_00176	COG0805	protein transport
RSC3_00177	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RSC3_00178	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_00179	COG2271	Major facilitator Superfamily
RSC3_00180	COG2271	Major facilitator Superfamily
RSC3_00181	COG4948	Mandelate Racemase Muconate Lactonizing
RSC3_00182	COG4948	Mandelate Racemase Muconate Lactonizing
RSC3_00183	COG2186	Transcriptional regulator
RSC3_00184	COG2721	sulfolactate sulfo-lyase activity
RSC3_00188	COG0745	RESPONSE REGULATOR receiver
RSC3_00189	COG2205	protein histidine kinase activity
RSC3_00190	COG1131	(ABC) transporter
RSC3_00195	COG3173	Aminoglycoside phosphotransferase
RSC3_00196	COG1846	Transcriptional regulator
RSC3_00197	COG0318	PFAM AMP-dependent synthetase and ligase
RSC3_00201	COG0789	Transcriptional regulator
RSC3_00206	COG0697	spore germination
RSC3_00207	COG1405	negative regulation of cell septum assembly
RSC3_00207	COG3012	SEC-C Motif Domain Protein
RSC3_00208	COG1131	(ABC) transporter
RSC3_00213	COG0583	DNA-binding transcription factor activity
RSC3_00214	COG1942	4-Oxalocrotonate Tautomerase
RSC3_00215	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_00218	COG1288	antiporter activity
RSC3_00220	COG0252	asparaginase activity
RSC3_00221	COG0456	acetyltransferase
RSC3_00223	COG1164	Oligoendopeptidase f
RSC3_00224	COG2261	transglycosylase associated protein
RSC3_00226	COG0247	lactate metabolic process
RSC3_00227	COG0277	FAD linked oxidase domain protein
RSC3_00228	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC3_00229	COG1447	Phosphotransferase system cellobiose-specific component IIA
RSC3_00230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC3_00231	COG1486	melibiose metabolic process
RSC3_00232	COG2188	Transcriptional regulator
RSC3_00233	COG3394	polysaccharide catabolic process
RSC3_00236	COG3591	Belongs to the peptidase S1B family
RSC3_00237	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_00239	COG1595	DNA-templated transcription, initiation
RSC3_00241	COG3773	Cell wall hydrolase
RSC3_00242	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RSC3_00243	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RSC3_00244	COG0791	NLP P60 protein
RSC3_00244	COG3883	PFAM NLP P60 protein
RSC3_00245	COG0791	NLP P60 protein
RSC3_00245	COG3883	PFAM NLP P60 protein
RSC3_00247	COG1131	(ABC) transporter
RSC3_00248	COG1309	transcriptional regulator
RSC3_00252	COG2310	stress, protein
RSC3_00253	COG2310	stress, protein
RSC3_00254	COG2310	stress, protein
RSC3_00255	COG0861	Integral membrane protein TerC family
RSC3_00259	COG3853	Toxic anion resistance protein (TelA)
RSC3_00260	COG0785	Cytochrome C biogenesis protein
RSC3_00262	COG2223	nitrite transmembrane transporter activity
RSC3_00264	COG0039	L-malate dehydrogenase activity
RSC3_00265	COG1620	l-lactate permease
RSC3_00266	COG1280	lysine exporter protein (LysE YggA)
RSC3_00267	COG1113	amino acid transport
RSC3_00268	COG1113	amino acid transport
RSC3_00269	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RSC3_00270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RSC3_00271	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RSC3_00272	COG3541	Predicted nucleotidyltransferase
RSC3_00273	COG0506	proline dehydrogenase activity
RSC3_00274	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_00275	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_00276	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC3_00277	COG2508	Transcriptional regulator
RSC3_00278	COG3689	TIGRFAM TIGR03943 family protein
RSC3_00279	COG0701	Predicted permease
RSC3_00280	COG3458	cephalosporin-C deacetylase activity
RSC3_00284	COG0765	amino acid transport
RSC3_00285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RSC3_00286	COG2249	NAD(P)H dehydrogenase (quinone) activity
RSC3_00287	COG1116	anion transmembrane transporter activity
RSC3_00288	COG2723	6-phospho-beta-galactosidase activity
RSC3_00290	COG3209	COG3209 Rhs family protein
RSC3_00293	COG5444	nuclease activity
RSC3_00299	COG1177	transmembrane transport
RSC3_00300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_00301	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_00302	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_00303	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_00304	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_00305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_00306	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
RSC3_00307	COG0697	spore germination
RSC3_00308	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC3_00310	COG2819	hydrolase of the alpha beta superfamily
RSC3_00311	COG3708	Transcriptional regulator
RSC3_00311	COG2207	Transcriptional regulator
RSC3_00313	COG2364	Membrane
RSC3_00320	COG1126	abc transporter atp-binding protein
RSC3_00321	COG0765	amino acid transport
RSC3_00322	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RSC3_00323	COG3829	transcription factor binding
RSC3_00324	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RSC3_00325	COG0833	amino acid
RSC3_00326	COG0010	Belongs to the arginase family
RSC3_00327	COG0010	Belongs to the arginase family
RSC3_00328	COG0583	DNA-binding transcription factor activity
RSC3_00329	COG0163	prenyltransferase activity
RSC3_00330	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RSC3_00341	COG5444	nuclease activity
RSC3_00346	COG2972	Histidine kinase
RSC3_00347	COG4753	response regulator
RSC3_00347	COG2207	Transcriptional regulator
RSC3_00348	COG4213	ABC transporter substrate-binding protein
RSC3_00350	COG4214	carbohydrate transport
RSC3_00351	COG2271	Major facilitator Superfamily
RSC3_00352	COG0456	acetyltransferase
RSC3_00352	COG1846	Transcriptional regulator
RSC3_00353	COG1874	Beta-galactosidase
RSC3_00354	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
RSC3_00357	COG3104	oligopeptide transport
RSC3_00358	COG5434	Belongs to the glycosyl hydrolase 28 family
RSC3_00360	COG0697	spore germination
RSC3_00362	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RSC3_00364	COG0789	Transcriptional regulator
RSC3_00365	COG1136	(ABC) transporter
RSC3_00366	COG0577	efflux transmembrane transporter activity
RSC3_00367	COG0745	RESPONSE REGULATOR receiver
RSC3_00368	COG5002	protein histidine kinase activity
RSC3_00368	COG3850	Histidine kinase
RSC3_00369	COG0840	transmembrane signaling receptor activity
RSC3_00370	COG0527	aspartate kinase activity
RSC3_00372	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_00373	COG4605	iron ion homeostasis
RSC3_00374	COG4604	ABC transporter, ATP-binding protein
RSC3_00375	COG4607	ABC-type enterochelin transport system periplasmic component
RSC3_00376	COG2814	Major facilitator Superfamily
RSC3_00377	COG1309	transcriptional regulator
RSC3_00379	COG0778	Nitroreductase
RSC3_00380	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RSC3_00381	COG0640	Transcriptional regulator
RSC3_00382	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC3_00383	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RSC3_00384	COG0531	amino acid
RSC3_00386	COG0531	amino acid
RSC3_00387	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_00388	COG0697	spore germination
RSC3_00390	COG4549	nuclear export factor GLE1
RSC3_00391	COG2372	response to copper ion
RSC3_00391	COG1276	copper resistance
RSC3_00392	COG1349	DNA-binding transcription factor activity
RSC3_00393	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RSC3_00394	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RSC3_00395	COG0243	molybdopterin cofactor binding
RSC3_00396	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RSC3_00397	COG2146	nitrite reductase [NAD(P)H] activity
RSC3_00398	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RSC3_00398	COG1587	Uroporphyrinogen-III synthase
RSC3_00399	COG1802	Transcriptional regulator
RSC3_00401	COG0471	metal ion transport
RSC3_00402	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RSC3_00404	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC3_00407	COG3959	Transketolase, thiamine diphosphate binding domain
RSC3_00408	COG3958	Transketolase
RSC3_00409	COG0561	phosphatase activity
RSC3_00410	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RSC3_00411	COG1914	H( )-stimulated, divalent metal cation uptake system
RSC3_00412	COG4336	lyase activity
RSC3_00413	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RSC3_00414	COG1984	allophanate hydrolase subunit 2
RSC3_00415	COG1984	allophanate hydrolase subunit 2
RSC3_00416	COG1414	Transcriptional regulator
RSC3_00417	COG2755	lipolytic protein G-D-S-L family
RSC3_00418	COG2213	PTS system mannitol-specific
RSC3_00419	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC3_00420	COG0246	Mannitol dehydrogenase
RSC3_00421	COG3711	transcriptional antiterminator
RSC3_00422	COG3711	transcriptional antiterminator
RSC3_00423	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_00424	COG1917	Cupin 2, conserved barrel domain protein
RSC3_00426	COG3871	stress protein (general stress protein 26)
RSC3_00429	COG2814	Major facilitator Superfamily
RSC3_00431	COG1522	sequence-specific DNA binding
RSC3_00432	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RSC3_00432	COG0551	DNA topoisomerase type I activity
RSC3_00433	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RSC3_00433	COG0551	DNA topoisomerase type I activity
RSC3_00434	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RSC3_00434	COG0551	DNA topoisomerase type I activity
RSC3_00435	COG0287	Prephenate dehydrogenase
RSC3_00436	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RSC3_00436	COG0512	Glutamine amidotransferase of anthranilate synthase
RSC3_00437	COG1605	Chorismate mutase
RSC3_00438	COG0028	Belongs to the TPP enzyme family
RSC3_00439	COG3397	chitin binding
RSC3_00441	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RSC3_00442	COG1914	H( )-stimulated, divalent metal cation uptake system
RSC3_00443	COG2261	transglycosylase associated protein
RSC3_00444	COG1027	Aspartate ammonia-lyase
RSC3_00445	COG1819	glycosyl
RSC3_00446	COG4876	unkown
RSC3_00447	COG2217	Heavy metal translocating P-type atpase
RSC3_00449	COG0662	Cupin 2, conserved barrel domain protein
RSC3_00451	COG0628	permease
RSC3_00452	COG1301	dicarboxylic acid transport
RSC3_00453	COG1131	(ABC) transporter
RSC3_00454	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RSC3_00456	COG1960	acyl-CoA dehydrogenase activity
RSC3_00459	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC3_00460	COG1181	Belongs to the D-alanine--D-alanine ligase family
RSC3_00461	COG1181	Belongs to the D-alanine--D-alanine ligase family
RSC3_00462	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RSC3_00464	COG0513	Belongs to the DEAD box helicase family
RSC3_00465	COG3402	PFAM membrane-flanked domain
RSC3_00466	COG3428	Bacterial PH domain
RSC3_00467	COG0705	Rhomboid family
RSC3_00468	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RSC3_00469	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RSC3_00470	COG0864	Transcriptional regulator
RSC3_00471	COG2337	Toxic component of a toxin-antitoxin (TA) module
RSC3_00472	COG1366	Belongs to the anti-sigma-factor antagonist family
RSC3_00473	COG1366	Belongs to the anti-sigma-factor antagonist family
RSC3_00474	COG2172	sigma factor antagonist activity
RSC3_00475	COG2208	phosphoserine phosphatase activity
RSC3_00478	COG1191	sigma factor activity
RSC3_00479	COG2208	phosphoserine phosphatase activity
RSC3_00480	COG2183	response to ionizing radiation
RSC3_00482	COG1309	transcriptional regulator
RSC3_00484	COG2409	Drug exporters of the RND superfamily
RSC3_00484	COG1033	growth of symbiont in host cell
RSC3_00485	COG3091	SprT-like family
RSC3_00489	COG0640	Transcriptional regulator
RSC3_00490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RSC3_00491	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RSC3_00492	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RSC3_00493	COG0726	polysaccharide deacetylase
RSC3_00494	COG3239	Fatty acid desaturase
RSC3_00495	COG1278	Cold shock
RSC3_00498	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC3_00499	COG0477	Major facilitator Superfamily
RSC3_00501	COG2364	Membrane
RSC3_00502	COG1846	Transcriptional regulator
RSC3_00503	COG0456	acetyltransferase
RSC3_00504	COG2808	Putative FMN-binding domain
RSC3_00505	COG2808	Putative FMN-binding domain
RSC3_00507	COG1733	regulation of RNA biosynthetic process
RSC3_00508	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC3_00510	COG0583	DNA-binding transcription factor activity
RSC3_00512	COG3545	Serine hydrolase
RSC3_00513	COG1733	regulation of RNA biosynthetic process
RSC3_00516	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
RSC3_00518	COG1113	amino acid transport
RSC3_00519	COG1113	amino acid transport
RSC3_00522	COG0596	Alpha beta hydrolase
RSC3_00523	COG5566	PFAM Mor transcription activator
RSC3_00525	COG1595	DNA-templated transcription, initiation
RSC3_00527	COG2755	lipolytic protein G-D-S-L family
RSC3_00527	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RSC3_00528	COG0494	nUDIX hydrolase
RSC3_00529	COG2814	Major facilitator Superfamily
RSC3_00530	COG1979	alcohol dehydrogenase
RSC3_00531	COG2972	Histidine kinase
RSC3_00531	COG0745	RESPONSE REGULATOR receiver
RSC3_00532	COG2972	Histidine kinase
RSC3_00532	COG0745	RESPONSE REGULATOR receiver
RSC3_00533	COG3279	Response regulator of the LytR AlgR family
RSC3_00535	COG3764	Sortase (surface protein transpeptidase)
RSC3_00536	COG2814	Major facilitator Superfamily
RSC3_00542	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RSC3_00543	COG0802	atpase or kinase
RSC3_00544	COG1214	PFAM Peptidase M22, glycoprotease
RSC3_00545	COG0456	acetyltransferase
RSC3_00546	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RSC3_00547	COG0488	(ABC) transporter
RSC3_00549	COG0315	cyclic pyranopterin monophosphate synthase activity
RSC3_00550	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
RSC3_00551	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RSC3_00552	COG0805	protein transport
RSC3_00554	COG1266	CAAX protease self-immunity
RSC3_00555	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RSC3_00556	COG0459	protein refolding
RSC3_00561	COG2720	vancomycin resistance protein
RSC3_00565	COG2135	peptidase activity
RSC3_00567	COG1309	transcriptional regulator
RSC3_00568	COG3848	Pyruvate phosphate dikinase
RSC3_00568	COG0574	Belongs to the PEP-utilizing enzyme family
RSC3_00570	COG3189	MarR family transcriptional regulator
RSC3_00571	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
RSC3_00572	COG2272	Belongs to the type-B carboxylesterase lipase family
RSC3_00573	COG2814	Major facilitator Superfamily
RSC3_00574	COG1842	Phage shock protein A
RSC3_00575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RSC3_00576	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RSC3_00577	COG4260	virion core protein, lumpy skin disease virus
RSC3_00580	COG1378	Sugar-specific transcriptional regulator TrmB
RSC3_00581	COG1280	lysine exporter protein (LysE YggA)
RSC3_00582	COG1280	lysine exporter protein (LysE YggA)
RSC3_00583	COG3339	Conserved Protein
RSC3_00585	COG0772	Belongs to the SEDS family
RSC3_00586	COG0772	Belongs to the SEDS family
RSC3_00592	COG0726	polysaccharide deacetylase
RSC3_00595	COG1609	Transcriptional regulator
RSC3_00596	COG1609	Transcriptional regulator
RSC3_00597	COG0366	Alpha amylase catalytic
RSC3_00598	COG2182	Extracellular solute-binding protein
RSC3_00599	COG1175	transmembrane transport
RSC3_00600	COG3833	ABC-type maltose transport systems, permease component
RSC3_00601	COG5521	maltodextrose utilization protein MalA
RSC3_00602	COG1554	hydrolase, family 65, central catalytic
RSC3_00603	COG0366	Alpha amylase catalytic
RSC3_00604	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RSC3_00605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RSC3_00606	COG1846	Transcriptional regulator
RSC3_00609	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RSC3_00610	COG0823	Involved in the tonB-independent uptake of proteins
RSC3_00611	COG0823	Involved in the tonB-independent uptake of proteins
RSC3_00616	COG0702	epimerase
RSC3_00618	COG2132	Multicopper oxidase
RSC3_00622	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RSC3_00623	COG0714	Associated with various cellular activities
RSC3_00624	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
RSC3_00625	COG1305	Transglutaminase-like
RSC3_00626	COG0519	Catalyzes the synthesis of GMP from XMP
RSC3_00626	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RSC3_00628	COG2252	PERMEase
RSC3_00631	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
RSC3_00633	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RSC3_00634	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RSC3_00635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RSC3_00636	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RSC3_00637	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RSC3_00638	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RSC3_00639	COG0047	phosphoribosylformylglycinamidine synthase activity
RSC3_00640	COG0047	phosphoribosylformylglycinamidine synthase activity
RSC3_00641	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RSC3_00642	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RSC3_00643	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RSC3_00644	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RSC3_00645	COG0138	bifunctional purine biosynthesis protein purh
RSC3_00646	COG0151	Belongs to the GarS family
RSC3_00648	COG2124	cytochrome p450
RSC3_00654	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RSC3_00655	COG1470	cell adhesion involved in biofilm formation
RSC3_00656	COG4496	protein, YerC YecD
RSC3_00657	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
RSC3_00658	COG0210	DNA helicase
RSC3_00659	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RSC3_00660	COG4851	CamS sex pheromone cAM373 precursor
RSC3_00661	COG2188	Transcriptional regulator
RSC3_00665	COG1735	metal-dependent hydrolase with the TIM-barrel fold
RSC3_00667	COG0626	cystathionine gamma-synthase activity
RSC3_00668	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RSC3_00669	COG3457	Alanine racemase
RSC3_00670	COG0363	glucosamine-6-phosphate deaminase activity
RSC3_00671	COG1285	pathogenesis
RSC3_00672	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC3_00673	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RSC3_00674	COG0154	amidase activity
RSC3_00675	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RSC3_00676	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RSC3_00679	COG4124	Belongs to the glycosyl hydrolase 26 family
RSC3_00680	COG1309	transcriptional regulator
RSC3_00681	COG1309	transcriptional regulator
RSC3_00682	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RSC3_00684	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RSC3_00685	COG1957	nucleoside hydrolase
RSC3_00686	COG1597	lipid kinase activity
RSC3_00687	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RSC3_00694	COG2723	6-phospho-beta-galactosidase activity
RSC3_00695	COG3711	transcriptional antiterminator
RSC3_00696	COG0457	Tetratricopeptide repeat
RSC3_00699	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
RSC3_00699	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RSC3_00700	COG3586	endonuclease activity
RSC3_00701	COG0697	spore germination
RSC3_00702	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC3_00703	COG0697	spore germination
RSC3_00704	COG0217	transcriptional regulatory protein
RSC3_00710	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_00711	COG0840	transmembrane signaling receptor activity
RSC3_00712	COG0109	protoheme IX farnesyltransferase activity
RSC3_00713	COG1309	transcriptional regulator
RSC3_00714	COG0471	metal ion transport
RSC3_00715	COG0471	metal ion transport
RSC3_00716	COG0488	(ABC) transporter
RSC3_00717	COG0583	DNA-binding transcription factor activity
RSC3_00719	COG1469	GTP cyclohydrolase I activity
RSC3_00720	COG1469	GTP cyclohydrolase I activity
RSC3_00724	COG0523	cobalamin synthesis protein
RSC3_00725	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
RSC3_00726	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RSC3_00727	COG0156	8-amino-7-oxononanoate synthase activity
RSC3_00728	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RSC3_00729	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RSC3_00730	COG2124	cytochrome p450
RSC3_00732	COG0789	Transcriptional regulator
RSC3_00733	COG2814	Major facilitator Superfamily
RSC3_00734	COG2814	Major facilitator Superfamily
RSC3_00735	COG0488	(ABC) transporter
RSC3_00736	COG0513	Belongs to the DEAD box helicase family
RSC3_00737	COG2130	NADP-dependent
RSC3_00740	COG0471	metal ion transport
RSC3_00742	COG1136	(ABC) transporter
RSC3_00746	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC3_00748	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
RSC3_00749	COG3858	chitin binding
RSC3_00750	COG5658	integral membrane protein
RSC3_00751	COG0640	Transcriptional regulator
RSC3_00752	COG1254	Belongs to the acylphosphatase family
RSC3_00753	COG2258	MOSC domain
RSC3_00756	COG0024	Methionine aminopeptidase
RSC3_00757	COG1368	sulfuric ester hydrolase activity
RSC3_00759	COG1115	amino acid carrier protein
RSC3_00760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC3_00760	COG1263	PTS System
RSC3_00761	COG0366	Alpha amylase catalytic
RSC3_00762	COG2188	Transcriptional regulator
RSC3_00769	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RSC3_00770	COG1045	serine acetyltransferase
RSC3_00771	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RSC3_00773	COG1215	transferase activity, transferring glycosyl groups
RSC3_00774	COG0463	Glycosyl transferase, family 2
RSC3_00774	COG0457	Tetratricopeptide repeat
RSC3_00776	COG0673	inositol 2-dehydrogenase activity
RSC3_00779	COG1733	regulation of RNA biosynthetic process
RSC3_00780	COG0778	Nitroreductase
RSC3_00781	COG0737	Belongs to the 5'-nucleotidase family
RSC3_00782	COG0693	protein deglycase activity
RSC3_00783	COG4840	Belongs to the UPF0435 family
RSC3_00784	COG1115	amino acid carrier protein
RSC3_00785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RSC3_00786	COG4980	gas vesicle protein
RSC3_00787	COG1295	ribonuclease BN
RSC3_00789	COG0477	Major facilitator Superfamily
RSC3_00791	COG0387	Pfam Sodium calcium exchanger
RSC3_00793	COG0535	radical SAM domain protein
RSC3_00795	COG0726	polysaccharide deacetylase
RSC3_00796	COG0371	Dehydrogenase
RSC3_00798	COG0598	Magnesium transport protein CorA
RSC3_00799	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
RSC3_00800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RSC3_00801	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RSC3_00802	COG4637	Psort location Cytoplasmic, score
RSC3_00807	COG1819	glycosyl
RSC3_00809	COG0477	Major facilitator Superfamily
RSC3_00811	COG1263	PTS System
RSC3_00811	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC3_00812	COG3711	transcriptional antiterminator
RSC3_00813	COG0288	reversible hydration of carbon dioxide
RSC3_00814	COG3002	Belongs to the UPF0753 family
RSC3_00815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RSC3_00816	COG5609	conserved protein (DUF2294)
RSC3_00818	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RSC3_00819	COG0022	dehydrogenase e1 component
RSC3_00820	COG0508	dehydrogenase complex catalyzes the overall conversion of
RSC3_00821	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RSC3_00822	COG3284	Transcriptional regulator
RSC3_00823	COG1742	UPF0060 membrane protein
RSC3_00824	COG1486	melibiose metabolic process
RSC3_00825	COG1737	Transcriptional regulator
RSC3_00826	COG1263	PTS System
RSC3_00826	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC3_00830	COG1733	regulation of RNA biosynthetic process
RSC3_00831	COG2259	Doxx family
RSC3_00832	COG2514	catechol 2,3-dioxygenase activity
RSC3_00834	COG3507	Belongs to the glycosyl hydrolase 43 family
RSC3_00835	COG2207	Transcriptional regulator
RSC3_00835	COG1917	Cupin 2, conserved barrel domain protein
RSC3_00836	COG1653	transport
RSC3_00837	COG2249	NAD(P)H dehydrogenase (quinone) activity
RSC3_00838	COG1051	belongs to the nudix hydrolase family
RSC3_00840	COG0392	lysyltransferase activity
RSC3_00840	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RSC3_00841	COG0384	phenazine biosynthesis protein PhzF
RSC3_00842	COG0778	Nitroreductase
RSC3_00845	COG1090	epimerase
RSC3_00846	COG2137	regulation of response to DNA damage stimulus
RSC3_00852	COG0463	Glycosyl transferase, family 2
RSC3_00854	COG4485	Bacterial membrane protein, YfhO
RSC3_00855	COG1988	membrane-bound metal-dependent
RSC3_00856	COG1194	a g-specific adenine glycosylase
RSC3_00858	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_00861	COG3557	Belongs to the UPF0374 family
RSC3_00862	COG1132	(ABC) transporter
RSC3_00863	COG0444	Belongs to the ABC transporter superfamily
RSC3_00864	COG4608	Belongs to the ABC transporter superfamily
RSC3_00865	COG0747	negative chemotaxis
RSC3_00866	COG0601	transmembrane transport
RSC3_00867	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSC3_00868	COG4129	membrane
RSC3_00869	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RSC3_00870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RSC3_00871	COG0735	belongs to the Fur family
RSC3_00883	COG0457	Tetratricopeptide repeat
RSC3_00888	COG5444	nuclease activity
RSC3_00891	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RSC3_00898	COG0710	3-dehydroquinate dehydratase activity
RSC3_00899	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RSC3_00900	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RSC3_00901	COG1116	anion transmembrane transporter activity
RSC3_00902	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RSC3_00903	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RSC3_00904	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RSC3_00906	COG1476	TRANSCRIPTIONal
RSC3_00908	COG1131	(ABC) transporter
RSC3_00912	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RSC3_00914	COG3382	B3 4 domain protein
RSC3_00915	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RSC3_00917	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RSC3_00918	COG0789	Transcriptional regulator
RSC3_00919	COG1664	Polymer-forming cytoskeletal
RSC3_00920	COG1664	Polymer-forming cytoskeletal
RSC3_00923	COG2766	serine protein kinase
RSC3_00924	COG2718	Belongs to the UPF0229 family
RSC3_00925	COG1566	PFAM secretion protein HlyD family protein
RSC3_00926	COG2814	Major facilitator Superfamily
RSC3_00927	COG0655	NAD(P)H dehydrogenase (quinone) activity
RSC3_00930	COG1725	Transcriptional regulator
RSC3_00931	COG1131	(ABC) transporter
RSC3_00932	COG1131	(ABC) transporter
RSC3_00933	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RSC3_00934	COG1278	Cold shock
RSC3_00936	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RSC3_00937	COG2011	ABC-type metal ion transport system permease component
RSC3_00938	COG1464	Belongs to the NlpA lipoprotein family
RSC3_00939	COG1823	symporter activity
RSC3_00940	COG1823	symporter activity
RSC3_00945	COG5577	PFAM Coat F domain
RSC3_00946	COG5002	protein histidine kinase activity
RSC3_00947	COG4191	Histidine kinase
RSC3_00948	COG0737	Belongs to the 5'-nucleotidase family
RSC3_00948	COG1525	nuclease
RSC3_00948	COG4085	toxin activity
RSC3_00949	COG0737	Belongs to the 5'-nucleotidase family
RSC3_00949	COG1525	nuclease
RSC3_00949	COG4085	toxin activity
RSC3_00950	COG1525	nuclease
RSC3_00950	COG0737	Belongs to the 5'-nucleotidase family
RSC3_00950	COG4085	toxin activity
RSC3_00951	COG3764	Sortase (surface protein transpeptidase)
RSC3_00952	COG0564	pseudouridine synthase activity
RSC3_00954	COG0517	IMP dehydrogenase activity
RSC3_00955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RSC3_00956	COG3153	acetyltransferase
RSC3_00956	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RSC3_00958	COG0488	(ABC) transporter
RSC3_00959	COG2116	formate transmembrane transporter activity
RSC3_00962	COG0604	alcohol dehydrogenase
RSC3_00963	COG0604	alcohol dehydrogenase
RSC3_00964	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RSC3_00965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RSC3_00966	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RSC3_00967	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RSC3_00968	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RSC3_00971	COG4585	Histidine kinase
RSC3_00971	COG2203	Gaf domain
RSC3_00972	COG2197	response regulator
RSC3_00973	COG2197	response regulator
RSC3_00974	COG0431	NADPH-dependent FMN reductase
RSC3_00977	COG1959	2 iron, 2 sulfur cluster binding
RSC3_00979	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RSC3_00979	COG1017	nitric oxide dioxygenase activity
RSC3_00980	COG2719	SpoVR family
RSC3_00981	COG1388	LysM domain
RSC3_00981	COG0791	NLP P60 protein
RSC3_00982	COG0583	DNA-binding transcription factor activity
RSC3_00983	COG0372	Belongs to the citrate synthase family
RSC3_00984	COG2133	pyrroloquinoline quinone binding
RSC3_00985	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_00986	COG0733	neurotransmitter:sodium symporter activity
RSC3_00990	COG5444	nuclease activity
RSC3_00991	COG2207	Transcriptional regulator
RSC3_00991	COG3708	Transcriptional regulator
RSC3_00992	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC3_00996	COG1595	DNA-templated transcription, initiation
RSC3_00997	COG0662	Cupin 2, conserved barrel domain protein
RSC3_00999	COG0667	Aldo Keto reductase
RSC3_01000	COG0204	Acyl-transferase
RSC3_01001	COG3152	Membrane
RSC3_01003	COG1309	transcriptional regulator
RSC3_01004	COG1253	flavin adenine dinucleotide binding
RSC3_01005	COG0789	Transcriptional regulator
RSC3_01007	COG1253	flavin adenine dinucleotide binding
RSC3_01012	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RSC3_01013	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RSC3_01014	COG0584	glycerophosphoryl diester phosphodiesterase
RSC3_01015	COG0584	glycerophosphoryl diester phosphodiesterase
RSC3_01017	COG0668	transmembrane transport
RSC3_01018	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RSC3_01020	COG0726	polysaccharide deacetylase
RSC3_01023	COG1757	Na H antiporter
RSC3_01024	COG2017	converts alpha-aldose to the beta-anomer
RSC3_01030	COG0589	response to stress
RSC3_01032	COG1132	(ABC) transporter
RSC3_01033	COG1132	(ABC) transporter
RSC3_01034	COG0702	epimerase
RSC3_01038	COG3842	ATPase activity
RSC3_01039	COG2508	Transcriptional regulator
RSC3_01041	COG0189	ligase activity
RSC3_01042	COG0189	ligase activity
RSC3_01043	COG4399	Belongs to the UPF0754 family
RSC3_01044	COG3679	Belongs to the UPF0342 family
RSC3_01045	COG0561	phosphatase activity
RSC3_01046	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RSC3_01047	COG0475	glutathione-regulated potassium exporter activity
RSC3_01048	COG0490	domain, Protein
RSC3_01049	COG1024	Enoyl-CoA hydratase
RSC3_01051	COG0457	Tetratricopeptide repeat
RSC3_01055	COG4152	abc transporter atp-binding protein
RSC3_01056	COG1668	transmembrane transport
RSC3_01057	COG0420	3'-5' exonuclease activity
RSC3_01058	COG4717	serine-type aminopeptidase activity
RSC3_01059	COG4717	serine-type aminopeptidase activity
RSC3_01060	COG3481	metal-dependent phosphohydrolase, HD sub domain
RSC3_01062	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RSC3_01068	COG1846	Transcriptional regulator
RSC3_01069	COG4980	gas vesicle protein
RSC3_01072	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RSC3_01073	COG0537	adenosine 5'-monophosphoramidase activity
RSC3_01074	COG1131	(ABC) transporter
RSC3_01075	COG4473	ABC transporter
RSC3_01077	COG1473	amidohydrolase
RSC3_01078	COG3069	C4-dicarboxylate transmembrane transporter activity
RSC3_01079	COG2329	Antibiotic biosynthesis monooxygenase
RSC3_01080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RSC3_01081	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RSC3_01082	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RSC3_01083	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
RSC3_01084	COG1309	transcriptional regulator
RSC3_01085	COG1511	domain protein
RSC3_01086	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RSC3_01087	COG1363	Peptidase, m42
RSC3_01089	COG1301	dicarboxylic acid transport
RSC3_01090	COG1234	tRNA 3'-trailer cleavage
RSC3_01091	COG0095	Lipoate-protein ligase
RSC3_01092	COG0318	PFAM AMP-dependent synthetase and ligase
RSC3_01093	COG1396	sequence-specific DNA binding
RSC3_01096	COG0501	Belongs to the peptidase M48B family
RSC3_01099	COG0697	spore germination
RSC3_01100	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RSC3_01101	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_01102	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_01103	COG0406	alpha-ribazole phosphatase activity
RSC3_01104	COG0840	transmembrane signaling receptor activity
RSC3_01105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RSC3_01105	COG0723	plastoquinol--plastocyanin reductase activity
RSC3_01106	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_01108	COG4903	ComK protein
RSC3_01110	COG0398	Pfam SNARE associated Golgi protein
RSC3_01111	COG0681	Belongs to the peptidase S26 family
RSC3_01113	COG1404	Belongs to the peptidase S8 family
RSC3_01114	COG1404	Belongs to the peptidase S8 family
RSC3_01116	COG2508	Transcriptional regulator
RSC3_01118	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RSC3_01119	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RSC3_01120	COG3257	ureidoglycine aminohydrolase activity
RSC3_01121	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RSC3_01122	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RSC3_01123	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RSC3_01124	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RSC3_01126	COG0549	Belongs to the carbamate kinase family
RSC3_01127	COG2814	Major facilitator Superfamily
RSC3_01128	COG0457	Tetratricopeptide repeat
RSC3_01130	COG1609	Transcriptional regulator
RSC3_01131	COG1653	transport
RSC3_01132	COG1175	transmembrane transport
RSC3_01133	COG0395	ABC-type sugar transport system, permease component
RSC3_01134	COG1486	melibiose metabolic process
RSC3_01135	COG3180	Ammonia monooxygenase
RSC3_01138	COG3546	catalase activity
RSC3_01139	COG0318	PFAM AMP-dependent synthetase and ligase
RSC3_01140	COG2814	Major facilitator Superfamily
RSC3_01140	COG0477	Major facilitator Superfamily
RSC3_01141	COG0477	Major facilitator Superfamily
RSC3_01141	COG2814	Major facilitator Superfamily
RSC3_01142	COG4533	DNA binding
RSC3_01144	COG5002	protein histidine kinase activity
RSC3_01145	COG0745	RESPONSE REGULATOR receiver
RSC3_01146	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
RSC3_01147	COG0725	ABC transporter, periplasmic molybdate-binding protein
RSC3_01148	COG4149	molybdate abc transporter
RSC3_01149	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
RSC3_01150	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
RSC3_01151	COG1074	ATP-dependent DNA helicase activity
RSC3_01152	COG1074	ATP-dependent DNA helicase activity
RSC3_01153	COG0420	3'-5' exonuclease activity
RSC3_01154	COG0420	3'-5' exonuclease activity
RSC3_01155	COG0419	ATPase involved in DNA repair
RSC3_01156	COG0419	ATPase involved in DNA repair
RSC3_01165	COG5337	Spore coat protein CotH
RSC3_01167	COG0179	Fumarylacetoacetate (FAA) hydrolase
RSC3_01172	COG0367	asparagine synthase
RSC3_01173	COG0004	ammonium transporteR
RSC3_01174	COG0004	ammonium transporteR
RSC3_01175	COG0347	Belongs to the P(II) protein family
RSC3_01176	COG0534	Mate efflux family protein
RSC3_01177	COG1917	Cupin 2, conserved barrel domain protein
RSC3_01177	COG2207	Transcriptional regulator
RSC3_01179	COG1609	Transcriptional regulator
RSC3_01180	COG0673	inositol 2-dehydrogenase activity
RSC3_01184	COG0697	spore germination
RSC3_01185	COG1279	arginine transmembrane transporter activity
RSC3_01186	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC3_01188	COG0076	glutamate decarboxylase activity
RSC3_01194	COG2153	protein acetylation
RSC3_01195	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_01196	COG2378	regulation of single-species biofilm formation
RSC3_01197	COG1410	methionine synthase
RSC3_01197	COG0646	methionine synthase
RSC3_01198	COG0646	methionine synthase
RSC3_01198	COG1410	methionine synthase
RSC3_01199	COG0646	methionine synthase
RSC3_01199	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RSC3_01200	COG1666	GTP binding
RSC3_01201	COG2996	Protein conserved in bacteria
RSC3_01204	COG1307	EDD domain protein, DegV family
RSC3_01205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC3_01207	COG0516	GMP reductase activity
RSC3_01210	COG0561	phosphatase activity
RSC3_01211	COG1073	alpha beta
RSC3_01212	COG2151	metal-sulfur cluster biosynthetic enzyme
RSC3_01213	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RSC3_01214	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RSC3_01215	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RSC3_01216	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RSC3_01217	COG0505	Belongs to the CarA family
RSC3_01218	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RSC3_01219	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RSC3_01220	COG1968	undecaprenyl-diphosphatase activity
RSC3_01223	COG2267	carboxylic ester hydrolase activity
RSC3_01225	COG1744	ABC transporter substrate-binding protein PnrA-like
RSC3_01228	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RSC3_01229	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RSC3_01231	COG5504	Zn-dependent protease
RSC3_01232	COG0444	Belongs to the ABC transporter superfamily
RSC3_01233	COG0444	Belongs to the ABC transporter superfamily
RSC3_01234	COG4608	Belongs to the ABC transporter superfamily
RSC3_01236	COG0601	transmembrane transport
RSC3_01237	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSC3_01240	COG0180	Tryptophanyl-tRNA synthetase
RSC3_01242	COG4166	transmembrane transport
RSC3_01243	COG0601	transmembrane transport
RSC3_01244	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSC3_01245	COG0444	Belongs to the ABC transporter superfamily
RSC3_01246	COG4608	Belongs to the ABC transporter superfamily
RSC3_01247	COG0456	acetyltransferase
RSC3_01248	COG1393	Belongs to the ArsC family
RSC3_01249	COG0861	Integral membrane protein TerC family
RSC3_01250	COG4862	establishment of competence for transformation
RSC3_01255	COG4565	transcriptional regulatory protein
RSC3_01256	COG3290	protein histidine kinase activity
RSC3_01257	COG4469	Competence protein
RSC3_01258	COG1164	Oligoendopeptidase f
RSC3_01259	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RSC3_01260	COG2346	COG2346, Truncated hemoglobins
RSC3_01261	COG0741	lytic transglycosylase activity
RSC3_01262	COG4116	CYTH
RSC3_01264	COG2357	RelA SpoT domain protein
RSC3_01265	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RSC3_01266	COG0564	pseudouridine synthase activity
RSC3_01267	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RSC3_01268	COG0569	domain protein
RSC3_01268	COG0475	glutathione-regulated potassium exporter activity
RSC3_01269	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RSC3_01270	COG0352	thiamine-phosphate diphosphorylase activity
RSC3_01272	COG2104	thiamine diphosphate biosynthetic process
RSC3_01273	COG2022	thiamine diphosphate biosynthetic process
RSC3_01274	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RSC3_01275	COG0351	phosphomethylpyrimidine kinase
RSC3_01276	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RSC3_01288	COG0210	DNA helicase
RSC3_01289	COG0210	DNA helicase
RSC3_01291	COG0586	Pfam SNARE associated Golgi protein
RSC3_01292	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RSC3_01293	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RSC3_01294	COG2246	polysaccharide biosynthetic process
RSC3_01295	COG2153	protein acetylation
RSC3_01296	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RSC3_01297	COG2382	esterase
RSC3_01302	COG0626	cystathionine gamma-synthase activity
RSC3_01303	COG0626	cystathionine gamma-synthase activity
RSC3_01304	COG5505	Protein of unknown function (DUF819)
RSC3_01307	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RSC3_01308	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RSC3_01310	COG3507	Belongs to the glycosyl hydrolase 43 family
RSC3_01313	COG0110	maltose O-acetyltransferase activity
RSC3_01315	COG0583	DNA-binding transcription factor activity
RSC3_01316	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RSC3_01317	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RSC3_01318	COG0583	DNA-binding transcription factor activity
RSC3_01319	COG0697	spore germination
RSC3_01320	COG0346	lactoylglutathione lyase activity
RSC3_01322	COG1388	LysM domain
RSC3_01322	COG3584	3D domain protein
RSC3_01323	COG2814	Major facilitator Superfamily
RSC3_01324	COG1309	transcriptional regulator
RSC3_01328	COG5444	nuclease activity
RSC3_01329	COG4195	phage-related replication protein
RSC3_01330	COG4195	phage-related replication protein
RSC3_01331	COG2856	Zn peptidase
RSC3_01332	COG1396	sequence-specific DNA binding
RSC3_01335	COG1522	sequence-specific DNA binding
RSC3_01336	COG1484	DNA-dependent DNA replication
RSC3_01341	COG1595	DNA-templated transcription, initiation
RSC3_01342	COG3728	DNA packaging
RSC3_01342	COG5484	DNA packaging
RSC3_01343	COG1783	phage Terminase large subunit
RSC3_01344	COG5518	Phage portal protein
RSC3_01345	COG0338	D12 class N6 adenine-specific DNA methyltransferase
RSC3_01346	COG4653	Phage capsid family
RSC3_01356	COG5412	phage tail tape measure protein
RSC3_01356	COG3953	SLT domain
RSC3_01357	COG3953	SLT domain
RSC3_01357	COG5280	Phage tail tape measure protein TP901
RSC3_01358	COG1652	LysM domain
RSC3_01359	COG4193	domain, Protein
RSC3_01361	COG3628	GPW Gp25 family protein
RSC3_01362	COG3299	homolog of phage Mu protein gp47
RSC3_01363	COG3778	Protein conserved in bacteria
RSC3_01370	COG1802	Transcriptional regulator
RSC3_01371	COG1063	alcohol dehydrogenase
RSC3_01372	COG1312	Catalyzes the dehydration of D-mannonate
RSC3_01373	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_01374	COG1063	alcohol dehydrogenase
RSC3_01375	COG2271	Major facilitator Superfamily
RSC3_01378	COG0306	phosphate transporter
RSC3_01379	COG1392	Phosphate transport regulator
RSC3_01380	COG0405	Gamma-glutamyltransferase
RSC3_01381	COG5578	integral membrane protein
RSC3_01382	COG2972	Histidine kinase
RSC3_01383	COG4753	response regulator
RSC3_01383	COG2207	Transcriptional regulator
RSC3_01384	COG1653	transport
RSC3_01385	COG1175	transmembrane transport
RSC3_01386	COG0395	ABC-type sugar transport system, permease component
RSC3_01387	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RSC3_01388	COG2207	Transcriptional regulator
RSC3_01389	COG2755	lipolytic protein G-D-S-L family
RSC3_01391	COG5578	integral membrane protein
RSC3_01392	COG3401	FG-GAP repeat protein
RSC3_01393	COG2755	lipolytic protein G-D-S-L family
RSC3_01394	COG3401	FG-GAP repeat protein
RSC3_01395	COG0667	Aldo Keto reductase
RSC3_01397	COG2755	lipolytic protein G-D-S-L family
RSC3_01398	COG1874	Beta-galactosidase
RSC3_01401	COG1653	transport
RSC3_01402	COG1653	transport
RSC3_01403	COG4209	transmembrane transport
RSC3_01404	COG0395	ABC-type sugar transport system, permease component
RSC3_01405	COG0531	amino acid
RSC3_01406	COG0531	amino acid
RSC3_01407	COG0346	lactoylglutathione lyase activity
RSC3_01408	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RSC3_01409	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RSC3_01410	COG2362	D-Aminopeptidase
RSC3_01411	COG0601	transmembrane transport
RSC3_01412	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSC3_01413	COG0444	Belongs to the ABC transporter superfamily
RSC3_01414	COG4166	transmembrane transport
RSC3_01415	COG1619	proteins homologs of microcin C7 resistance protein MccF
RSC3_01416	COG4948	Mandelate Racemase Muconate Lactonizing
RSC3_01417	COG4948	Mandelate Racemase Muconate Lactonizing
RSC3_01418	COG0791	NLP P60 protein
RSC3_01419	COG4608	Belongs to the ABC transporter superfamily
RSC3_01422	COG1834	amidinotransferase
RSC3_01423	COG1607	acyl-coa hydrolase
RSC3_01424	COG2323	membrane
RSC3_01425	COG3866	Pectate lyase
RSC3_01430	COG2318	DinB family
RSC3_01431	COG2076	Multidrug Resistance protein
RSC3_01432	COG2076	Multidrug Resistance protein
RSC3_01433	COG0788	formyltetrahydrofolate deformylase activity
RSC3_01434	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RSC3_01435	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RSC3_01436	COG1764	response to oxidative stress
RSC3_01437	COG1846	Transcriptional regulator
RSC3_01438	COG1764	response to oxidative stress
RSC3_01440	COG0590	tRNA wobble adenosine to inosine editing
RSC3_01441	COG0406	alpha-ribazole phosphatase activity
RSC3_01444	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RSC3_01445	COG1404	Belongs to the peptidase S8 family
RSC3_01447	COG2239	Acts as a magnesium transporter
RSC3_01449	COG0789	Transcriptional regulator
RSC3_01451	COG1846	Transcriptional regulator
RSC3_01452	COG3285	dna ligase
RSC3_01452	COG1793	dna ligase
RSC3_01453	COG3285	dna ligase
RSC3_01453	COG1793	dna ligase
RSC3_01454	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RSC3_01455	COG5001	Diguanylate cyclase
RSC3_01455	COG3300	MHYT domain
RSC3_01456	COG0586	Pfam SNARE associated Golgi protein
RSC3_01457	COG0586	Pfam SNARE associated Golgi protein
RSC3_01458	COG0861	Integral membrane protein TerC family
RSC3_01459	COG1191	sigma factor activity
RSC3_01463	COG0501	Belongs to the peptidase M48B family
RSC3_01464	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RSC3_01465	COG0768	penicillin binding
RSC3_01468	COG3594	Acyltransferase
RSC3_01469	COG5002	protein histidine kinase activity
RSC3_01470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RSC3_01472	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
RSC3_01473	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
RSC3_01474	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
RSC3_01475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RSC3_01476	COG0436	Aminotransferase
RSC3_01477	COG1850	ribulose-bisphosphate carboxylase activity
RSC3_01478	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
RSC3_01478	COG0235	Class ii aldolase
RSC3_01479	COG0235	Class ii aldolase
RSC3_01479	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
RSC3_01480	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
RSC3_01481	COG0346	lactoylglutathione lyase activity
RSC3_01482	COG3339	Conserved Protein
RSC3_01484	COG3852	Histidine kinase
RSC3_01485	COG1846	Transcriptional regulator
RSC3_01486	COG1360	Flagellar Motor Protein
RSC3_01487	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RSC3_01488	COG0542	response to heat
RSC3_01489	COG3949	Membrane
RSC3_01490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RSC3_01491	COG0720	synthase
RSC3_01492	COG0602	queuosine metabolic process
RSC3_01493	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RSC3_01495	COG0457	Tetratricopeptide repeat
RSC3_01498	COG3739	integral membrane protein
RSC3_01500	COG3655	Transcriptional regulator
RSC3_01509	COG4873	Protein conserved in bacteria
RSC3_01511	COG3773	Cell wall hydrolase
RSC3_01512	COG2244	polysaccharide biosynthetic process
RSC3_01513	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC3_01514	COG2217	Heavy metal translocating P-type atpase
RSC3_01515	COG2217	Heavy metal translocating P-type atpase
RSC3_01516	COG0006	proline dipeptidase activity
RSC3_01519	COG1609	Transcriptional regulator
RSC3_01520	COG3711	transcriptional antiterminator
RSC3_01521	COG1263	PTS System
RSC3_01521	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC3_01521	COG2190	(PTS) system
RSC3_01522	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC3_01523	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RSC3_01525	COG1533	DNA photolyase activity
RSC3_01526	COG0456	acetyltransferase
RSC3_01527	COG0840	transmembrane signaling receptor activity
RSC3_01528	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_01529	COG2084	Dehydrogenase
RSC3_01530	COG2340	Cysteine-rich secretory protein family
RSC3_01531	COG0768	penicillin binding
RSC3_01532	COG4191	Histidine kinase
RSC3_01533	COG0436	Aminotransferase
RSC3_01535	COG1714	RDD family
RSC3_01537	COG0784	Response regulator, receiver
RSC3_01537	COG0835	chemotaxis
RSC3_01539	COG2814	Major facilitator Superfamily
RSC3_01540	COG2814	Major facilitator Superfamily
RSC3_01541	COG1376	ErfK ybiS ycfS ynhG family protein
RSC3_01542	COG1408	metallophosphoesterase
RSC3_01543	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_01544	COG2200	EAL domain
RSC3_01547	COG4703	Protein of unknown function (DUF1797)
RSC3_01548	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
RSC3_01550	COG0517	IMP dehydrogenase activity
RSC3_01551	COG0583	DNA-binding transcription factor activity
RSC3_01552	COG0716	FMN binding
RSC3_01554	COG0716	FMN binding
RSC3_01555	COG2171	N-acyltransferase activity
RSC3_01556	COG1473	amidohydrolase
RSC3_01558	COG0450	alkyl hydroperoxide reductase
RSC3_01559	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC3_01562	COG0746	molybdenum cofactor guanylyltransferase activity
RSC3_01563	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RSC3_01564	COG0303	'Molybdopterin
RSC3_01565	COG1763	Mo-molybdopterin cofactor biosynthetic process
RSC3_01566	COG0314	molybdopterin synthase activity
RSC3_01567	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
RSC3_01569	COG1132	(ABC) transporter
RSC3_01570	COG1132	(ABC) transporter
RSC3_01572	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RSC3_01573	COG1136	(ABC) transporter
RSC3_01574	COG0577	efflux transmembrane transporter activity
RSC3_01576	COG1349	DNA-binding transcription factor activity
RSC3_01577	COG1105	Belongs to the carbohydrate kinase PfkB family
RSC3_01578	COG1105	Belongs to the carbohydrate kinase PfkB family
RSC3_01579	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSC3_01579	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSC3_01579	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC3_01583	COG0488	(ABC) transporter
RSC3_01584	COG0488	(ABC) transporter
RSC3_01586	COG2309	aminopeptidase activity
RSC3_01588	COG1077	Cell shape determining protein MreB Mrl
RSC3_01589	COG2002	toxin-antitoxin pair type II binding
RSC3_01590	COG3852	Histidine kinase
RSC3_01591	COG0569	domain protein
RSC3_01592	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RSC3_01593	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RSC3_01594	COG5503	Protein of unknown function (DUF1447)
RSC3_01595	COG0561	phosphatase activity
RSC3_01596	COG0242	peptide deformylase activity
RSC3_01598	COG0497	DNA recombination
RSC3_01600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RSC3_01601	COG0022	dehydrogenase e1 component
RSC3_01602	COG0508	dehydrogenase complex catalyzes the overall conversion of
RSC3_01603	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RSC3_01604	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC3_01606	COG1982	Orn Lys Arg decarboxylase major
RSC3_01607	COG4476	Belongs to the UPF0223 family
RSC3_01608	COG4493	Belongs to the UPF0637 family
RSC3_01610	COG0483	inositol monophosphate 1-phosphatase activity
RSC3_01614	COG1595	DNA-templated transcription, initiation
RSC3_01617	COG1217	gtp-binding protein TYPA
RSC3_01619	COG1846	Transcriptional regulator
RSC3_01620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RSC3_01621	COG4896	Protein conserved in bacteria
RSC3_01623	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RSC3_01624	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RSC3_01625	COG2066	Belongs to the glutaminase family
RSC3_01626	COG4838	Belongs to the UPF0358 family
RSC3_01627	COG0772	Belongs to the SEDS family
RSC3_01628	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RSC3_01629	COG1612	heme a metabolic process
RSC3_01630	COG0109	protoheme IX farnesyltransferase activity
RSC3_01631	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RSC3_01631	COG2010	Cytochrome c
RSC3_01632	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RSC3_01632	COG2010	Cytochrome c
RSC3_01633	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RSC3_01634	COG1845	cytochrome c oxidase, subunit III
RSC3_01635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RSC3_01636	COG3336	cytochrome c oxidase
RSC3_01638	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
RSC3_01639	COG2340	Cysteine-rich secretory protein family
RSC3_01644	COG3679	Belongs to the UPF0342 family
RSC3_01645	COG4471	UPF0298 protein
RSC3_01647	COG0742	ribosomal rna small subunit methyltransferase
RSC3_01648	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RSC3_01649	COG3314	Sporulation integral membrane protein YlbJ
RSC3_01650	COG3480	Lon protease (S16) C-terminal proteolytic domain
RSC3_01651	COG1323	Belongs to the UPF0348 family
RSC3_01652	COG1399	metal-binding, possibly nucleic acid-binding protein
RSC3_01653	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RSC3_01655	COG0454	-acetyltransferase
RSC3_01656	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RSC3_01657	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
RSC3_01658	COG2001	Belongs to the MraZ family
RSC3_01659	COG0275	rRNA processing
RSC3_01660	COG4839	cell division protein FtsL
RSC3_01661	COG0768	penicillin binding
RSC3_01662	COG0768	penicillin binding
RSC3_01663	COG0768	penicillin binding
RSC3_01665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RSC3_01666	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RSC3_01667	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RSC3_01668	COG0772	Belongs to the SEDS family
RSC3_01669	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RSC3_01670	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RSC3_01671	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RSC3_01673	COG3879	Bacterial protein of unknown function (DUF881)
RSC3_01674	COG3879	Bacterial protein of unknown function (DUF881)
RSC3_01675	COG3856	small basic protein
RSC3_01676	COG0849	cell division
RSC3_01677	COG0849	cell division
RSC3_01678	COG0849	cell division
RSC3_01679	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RSC3_01680	COG4412	M6 family metalloprotease domain protein
RSC3_01680	COG1404	Belongs to the peptidase S8 family
RSC3_01681	COG1404	Belongs to the peptidase S8 family
RSC3_01681	COG4412	M6 family metalloprotease domain protein
RSC3_01682	COG1404	Belongs to the peptidase S8 family
RSC3_01682	COG4412	M6 family metalloprotease domain protein
RSC3_01683	COG4412	M6 family metalloprotease domain protein
RSC3_01683	COG1404	Belongs to the peptidase S8 family
RSC3_01685	COG1191	sigma factor activity
RSC3_01686	COG1191	sigma factor activity
RSC3_01687	COG1119	ATPase activity
RSC3_01688	COG0500	methyltransferase
RSC3_01689	COG1873	PFAM PRC-barrel domain
RSC3_01690	COG1496	oxidoreductase activity
RSC3_01691	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RSC3_01692	COG1799	cell septum assembly
RSC3_01693	COG0762	integral membrane protein
RSC3_01694	COG2302	S4 RNA-binding domain
RSC3_01695	COG3599	regulation of cell shape
RSC3_01696	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RSC3_01697	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RSC3_01698	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RSC3_01699	COG0564	pseudouridine synthase activity
RSC3_01701	COG2233	PERMEase
RSC3_01702	COG0540	Belongs to the ATCase OTCase family
RSC3_01703	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RSC3_01704	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RSC3_01705	COG0505	Belongs to the CarA family
RSC3_01706	COG0505	Belongs to the CarA family
RSC3_01707	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RSC3_01708	COG0543	2 iron, 2 sulfur cluster binding
RSC3_01709	COG0167	dihydroorotate dehydrogenase activity
RSC3_01710	COG0284	orotidine-5'-phosphate decarboxylase activity
RSC3_01711	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RSC3_01713	COG0175	sulfate reduction
RSC3_01714	COG2046	Belongs to the sulfate adenylyltransferase family
RSC3_01715	COG0529	Catalyzes the synthesis of activated sulfate
RSC3_01716	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RSC3_01717	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
RSC3_01718	COG1648	precorrin-2 dehydrogenase activity
RSC3_01720	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RSC3_01721	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RSC3_01722	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RSC3_01723	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RSC3_01724	COG1561	YicC-like family, N-terminal region
RSC3_01725	COG2052	Domain of unknown function (DUF370)
RSC3_01726	COG0194	GDP metabolic process
RSC3_01727	COG1758	RNA polymerase activity
RSC3_01728	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RSC3_01729	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RSC3_01730	COG0242	peptide deformylase activity
RSC3_01731	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RSC3_01732	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RSC3_01732	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RSC3_01733	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RSC3_01734	COG0631	protein serine/threonine phosphatase activity
RSC3_01735	COG0515	serine threonine protein kinase
RSC3_01735	COG2815	serine threonine protein kinase
RSC3_01736	COG1162	GTPase activity
RSC3_01737	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RSC3_01738	COG1564	THIamine pyrophosphokinase
RSC3_01739	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RSC3_01740	COG1302	Protein conserved in bacteria
RSC3_01741	COG1461	Dihydroxyacetone kinase
RSC3_01742	COG1461	Dihydroxyacetone kinase
RSC3_01743	COG1760	l-serine dehydratase
RSC3_01744	COG1760	l-serine dehydratase
RSC3_01745	COG1760	l-serine dehydratase
RSC3_01746	COG1760	l-serine dehydratase
RSC3_01747	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RSC3_01748	COG1349	DNA-binding transcription factor activity
RSC3_01749	COG0416	fatty acid biosynthetic process
RSC3_01750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RSC3_01751	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_01752	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RSC3_01753	COG0571	ribonuclease III activity
RSC3_01754	COG1196	nuclear chromosome segregation
RSC3_01755	COG0552	protein localization to endoplasmic reticulum
RSC3_01756	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
RSC3_01757	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RSC3_01758	COG0228	four-way junction DNA binding
RSC3_01759	COG1837	Belongs to the UPF0109 family
RSC3_01761	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RSC3_01762	COG0336	Belongs to the RNA methyltransferase TrmD family
RSC3_01763	COG0335	large ribosomal subunit rRNA binding
RSC3_01764	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RSC3_01765	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RSC3_01767	COG2257	FlhB HrpN YscU SpaS Family
RSC3_01768	COG0045	succinate-CoA ligase (ADP-forming) activity
RSC3_01769	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RSC3_01770	COG0758	DNA mediated transformation
RSC3_01771	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RSC3_01772	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
RSC3_01773	COG4974	Belongs to the 'phage' integrase family
RSC3_01774	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RSC3_01775	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RSC3_01776	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RSC3_01777	COG1815	bacterial-type flagellum-dependent cell motility
RSC3_01778	COG1558	bacterial-type flagellum-dependent cell motility
RSC3_01779	COG1677	Flagellar hook-basal body complex protein FliE
RSC3_01780	COG1766	The M ring may be actively involved in energy transduction
RSC3_01781	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RSC3_01782	COG1317	bacterial-type flagellum organization
RSC3_01783	COG1157	protein secretion by the type III secretion system
RSC3_01784	COG2882	bacterial-type flagellum organization
RSC3_01786	COG3144	bacterial-type flagellum assembly
RSC3_01787	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RSC3_01788	COG4786	Flagellar basal body rod
RSC3_01789	COG1582	Flagellar protein (FlbD)
RSC3_01790	COG1580	Controls the rotational direction of flagella during chemotaxis
RSC3_01791	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RSC3_01792	COG1776	CheC inhibitor of MCP methylation
RSC3_01792	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RSC3_01793	COG2201	protein-glutamate methylesterase activity
RSC3_01794	COG3190	flagellar
RSC3_01795	COG1338	Plays a role in the flagellum-specific transport system
RSC3_01796	COG1987	bacterial-type flagellum assembly
RSC3_01797	COG1684	flagellar biosynthetic protein fliR
RSC3_01798	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RSC3_01799	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RSC3_01800	COG1419	protein localization to endoplasmic reticulum
RSC3_01801	COG0455	bacterial-type flagellum organization
RSC3_01802	COG2201	protein-glutamate methylesterase activity
RSC3_01803	COG2201	protein-glutamate methylesterase activity
RSC3_01804	COG0643	Histidine kinase
RSC3_01804	COG2198	Histidine kinase
RSC3_01805	COG0835	chemotaxis
RSC3_01806	COG1776	CheC inhibitor of MCP methylation
RSC3_01807	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RSC3_01808	COG1191	sigma factor activity
RSC3_01810	COG0052	Belongs to the universal ribosomal protein uS2 family
RSC3_01811	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RSC3_01812	COG0528	UMP kinase activity
RSC3_01813	COG0233	cytoplasmic translational termination
RSC3_01814	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RSC3_01815	COG4589	Belongs to the CDS family
RSC3_01816	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RSC3_01817	COG0750	zinc metalloprotease
RSC3_01818	COG0442	prolyl-tRNA aminoacylation
RSC3_01819	COG0442	prolyl-tRNA aminoacylation
RSC3_01820	COG2176	DNA-directed DNA polymerase activity
RSC3_01827	COG0779	Required for maturation of 30S ribosomal subunits
RSC3_01828	COG0195	Participates in both transcription termination and antitermination
RSC3_01829	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RSC3_01830	COG1358	cellular component organization or biogenesis
RSC3_01831	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RSC3_01832	COG1550	Protein conserved in bacteria
RSC3_01833	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RSC3_01834	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RSC3_01835	COG0196	riboflavin kinase activity
RSC3_01836	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RSC3_01837	COG1185	polyribonucleotide nucleotidyltransferase activity
RSC3_01838	COG0726	polysaccharide deacetylase
RSC3_01839	COG0612	Peptidase, M16
RSC3_01840	COG1873	PFAM PRC-barrel domain
RSC3_01841	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RSC3_01842	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RSC3_01843	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RSC3_01844	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RSC3_01845	COG0527	aspartate kinase activity
RSC3_01847	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RSC3_01848	COG0740	serine-type endopeptidase activity
RSC3_01850	COG4980	gas vesicle protein
RSC3_01850	COG1674	ftsk spoiiie
RSC3_01851	COG2188	Transcriptional regulator
RSC3_01852	COG2814	Major facilitator Superfamily
RSC3_01853	COG0612	Peptidase, M16
RSC3_01854	COG0612	Peptidase, M16
RSC3_01855	COG0300	oxidoreductase activity
RSC3_01858	COG1426	Protein conserved in bacteria
RSC3_01859	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RSC3_01860	COG1058	Belongs to the CinA family
RSC3_01860	COG1546	Belongs to the CinA family
RSC3_01862	COG1418	mRNA catabolic process
RSC3_01863	COG1692	metallophosphoesterase
RSC3_01864	COG2359	stage V sporulation protein S
RSC3_01865	COG1063	alcohol dehydrogenase
RSC3_01867	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RSC3_01868	COG4550	Control of competence regulator ComK, YlbF/YmcA
RSC3_01870	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RSC3_01871	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RSC3_01872	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RSC3_01875	COG0457	Tetratricopeptide repeat
RSC3_01877	COG5444	nuclease activity
RSC3_01879	COG3677	Transposase
RSC3_01881	COG5484	DNA packaging
RSC3_01882	COG5484	DNA packaging
RSC3_01883	COG5484	DNA packaging
RSC3_01884	COG1783	phage Terminase large subunit
RSC3_01885	COG1783	phage Terminase large subunit
RSC3_01886	COG1783	phage Terminase large subunit
RSC3_01887	COG5518	Phage portal protein
RSC3_01888	COG2369	cell adhesion
RSC3_01890	COG0338	D12 class N6 adenine-specific DNA methyltransferase
RSC3_01891	COG4653	Phage capsid family
RSC3_01896	COG5444	nuclease activity
RSC3_01897	COG5444	nuclease activity
RSC3_01901	COG0523	cobalamin synthesis protein
RSC3_01905	COG1231	oxidoreductase activity
RSC3_01906	COG3619	membrane
RSC3_01907	COG3263	regulation of cellular component size
RSC3_01909	COG2814	Major facilitator Superfamily
RSC3_01911	COG0393	Putative heavy-metal-binding
RSC3_01912	COG0398	Pfam SNARE associated Golgi protein
RSC3_01913	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RSC3_01914	COG1819	glycosyl
RSC3_01915	COG0531	amino acid
RSC3_01916	COG5577	PFAM Coat F domain
RSC3_01918	COG3858	chitin binding
RSC3_01918	COG1388	LysM domain
RSC3_01919	COG1309	transcriptional regulator
RSC3_01920	COG3631	Ketosteroid isomerase-related protein
RSC3_01921	COG0702	epimerase
RSC3_01923	COG1764	response to oxidative stress
RSC3_01924	COG2076	Multidrug Resistance protein
RSC3_01925	COG2076	Multidrug Resistance protein
RSC3_01928	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RSC3_01929	COG1923	regulation of RNA biosynthetic process
RSC3_01931	COG1780	Probably involved in ribonucleotide reductase function
RSC3_01932	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RSC3_01933	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RSC3_01934	COG4112	unkown
RSC3_01937	COG0735	belongs to the Fur family
RSC3_01938	COG1802	Transcriptional regulator
RSC3_01939	COG0697	spore germination
RSC3_01945	COG1309	transcriptional regulator
RSC3_01953	COG4282	regulation of fungal-type cell wall biogenesis
RSC3_01954	COG5444	nuclease activity
RSC3_01960	COG2814	Major facilitator Superfamily
RSC3_01961	COG0457	Tetratricopeptide repeat
RSC3_01964	COG4413	Urea transporter
RSC3_01966	COG0831	urea catabolic process
RSC3_01967	COG0832	Belongs to the urease beta subunit family
RSC3_01968	COG0804	urea catabolic process
RSC3_01970	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
RSC3_01972	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RSC3_01974	COG0829	nickel cation binding
RSC3_01977	COG1695	Transcriptional regulator
RSC3_01983	COG0464	growth
RSC3_01984	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RSC3_01985	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RSC3_01986	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RSC3_01987	COG0789	Transcriptional regulator
RSC3_01988	COG0174	glutamine synthetase
RSC3_01994	COG0174	glutamine synthetase
RSC3_02003	COG0490	domain, Protein
RSC3_02004	COG0475	glutathione-regulated potassium exporter activity
RSC3_02006	COG1073	alpha beta
RSC3_02016	COG1309	transcriptional regulator
RSC3_02017	COG2076	Multidrug Resistance protein
RSC3_02018	COG2076	Multidrug Resistance protein
RSC3_02019	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RSC3_02022	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC3_02023	COG3546	catalase activity
RSC3_02030	COG1846	Transcriptional regulator
RSC3_02031	COG0346	lactoylglutathione lyase activity
RSC3_02032	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RSC3_02033	COG0655	NAD(P)H dehydrogenase (quinone) activity
RSC3_02038	COG3209	COG3209 Rhs family protein
RSC3_02039	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RSC3_02040	COG1388	LysM domain
RSC3_02041	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RSC3_02042	COG4224	UPF0291 protein
RSC3_02043	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RSC3_02045	COG3763	UPF0154 protein
RSC3_02047	COG0785	Cytochrome C biogenesis protein
RSC3_02048	COG2201	protein-glutamate methylesterase activity
RSC3_02049	COG4846	Membrane protein involved in cytochrome C biogenesis
RSC3_02051	COG0071	Belongs to the small heat shock protein (HSP20) family
RSC3_02054	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RSC3_02055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RSC3_02056	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC3_02060	COG0824	Thioesterase
RSC3_02065	COG4841	protein insertion into membrane
RSC3_02066	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RSC3_02067	COG1832	CoA-binding protein
RSC3_02069	COG0187	DNA topoisomerase II activity
RSC3_02070	COG0187	DNA topoisomerase II activity
RSC3_02071	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RSC3_02073	COG1609	Transcriptional regulator
RSC3_02076	COG2160	L-arabinose isomerase activity
RSC3_02083	COG1115	amino acid carrier protein
RSC3_02085	COG2181	nitrate reductase activity
RSC3_02086	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RSC3_02087	COG1140	nitrate reductase beta subunit
RSC3_02088	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RSC3_02095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RSC3_02096	COG2223	nitrite transmembrane transporter activity
RSC3_02100	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
RSC3_02102	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RSC3_02104	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RSC3_02109	COG0477	Major facilitator Superfamily
RSC3_02110	COG3420	alginic acid biosynthetic process
RSC3_02111	COG3420	alginic acid biosynthetic process
RSC3_02112	COG1114	Component of the transport system for branched-chain amino acids
RSC3_02114	COG1687	branched-chain amino acid
RSC3_02115	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RSC3_02116	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC3_02117	COG1064	alcohol dehydrogenase
RSC3_02121	COG1024	Enoyl-CoA hydratase
RSC3_02122	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_02123	COG2084	Dehydrogenase
RSC3_02124	COG1960	acyl-CoA dehydrogenase activity
RSC3_02125	COG1482	cell wall glycoprotein biosynthetic process
RSC3_02126	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSC3_02126	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSC3_02126	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC3_02129	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC3_02129	COG3711	transcriptional antiterminator
RSC3_02132	COG1725	Transcriptional regulator
RSC3_02133	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_02134	COG1312	Catalyzes the dehydration of D-mannonate
RSC3_02139	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RSC3_02141	COG1609	Transcriptional regulator
RSC3_02142	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RSC3_02143	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RSC3_02144	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
RSC3_02147	COG1649	PFAM Uncharacterised BCR, COG1649
RSC3_02148	COG1649	PFAM Uncharacterised BCR, COG1649
RSC3_02149	COG2404	hydrolase activity, acting on ester bonds
RSC3_02150	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RSC3_02152	COG0438	transferase activity, transferring glycosyl groups
RSC3_02153	COG2027	D-alanyl-D-alanine carboxypeptidase
RSC3_02157	COG1309	transcriptional regulator
RSC3_02158	COG1252	NADH dehydrogenase
RSC3_02159	COG1252	NADH dehydrogenase
RSC3_02162	COG0166	Belongs to the GPI family
RSC3_02164	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RSC3_02165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RSC3_02166	COG1024	Enoyl-CoA hydratase
RSC3_02167	COG1024	Enoyl-CoA hydratase
RSC3_02168	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RSC3_02169	COG0511	ligase activity, forming carbon-carbon bonds
RSC3_02170	COG0439	Biotin carboxylase
RSC3_02172	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RSC3_02172	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_02173	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_02174	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_02175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_02176	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_02177	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_02178	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_02179	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_02180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_02181	COG0318	PFAM AMP-dependent synthetase and ligase
RSC3_02182	COG1960	acyl-CoA dehydrogenase activity
RSC3_02183	COG2249	NAD(P)H dehydrogenase (quinone) activity
RSC3_02184	COG1733	regulation of RNA biosynthetic process
RSC3_02185	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RSC3_02186	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RSC3_02188	COG2323	membrane
RSC3_02189	COG2323	membrane
RSC3_02191	COG0306	phosphate transporter
RSC3_02192	COG0175	sulfate reduction
RSC3_02193	COG1809	phosphosulfolactate synthase activity
RSC3_02194	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC3_02195	COG4948	Mandelate Racemase Muconate Lactonizing
RSC3_02196	COG2814	Major facilitator Superfamily
RSC3_02197	COG0463	Glycosyl transferase, family 2
RSC3_02200	COG0493	'glutamate synthase
RSC3_02201	COG0070	glutamate synthase
RSC3_02201	COG0067	glutamate synthase
RSC3_02201	COG0069	glutamate synthase activity
RSC3_02202	COG0583	DNA-binding transcription factor activity
RSC3_02207	COG1132	(ABC) transporter
RSC3_02209	COG0300	oxidoreductase activity
RSC3_02210	COG0300	oxidoreductase activity
RSC3_02211	COG0574	Belongs to the PEP-utilizing enzyme family
RSC3_02211	COG3848	Pyruvate phosphate dikinase
RSC3_02212	COG0574	Belongs to the PEP-utilizing enzyme family
RSC3_02212	COG3848	Pyruvate phosphate dikinase
RSC3_02213	COG0477	Major facilitator Superfamily
RSC3_02214	COG0243	molybdopterin cofactor binding
RSC3_02215	COG1846	Transcriptional regulator
RSC3_02216	COG2814	Major facilitator Superfamily
RSC3_02217	COG0531	amino acid
RSC3_02218	COG0531	amino acid
RSC3_02219	COG0531	amino acid
RSC3_02223	COG0531	amino acid
RSC3_02224	COG0531	amino acid
RSC3_02225	COG0697	spore germination
RSC3_02227	COG0488	(ABC) transporter
RSC3_02228	COG0488	(ABC) transporter
RSC3_02229	COG0840	transmembrane signaling receptor activity
RSC3_02230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RSC3_02232	COG1404	Belongs to the peptidase S8 family
RSC3_02233	COG1404	Belongs to the peptidase S8 family
RSC3_02235	COG1309	transcriptional regulator
RSC3_02236	COG1846	Transcriptional regulator
RSC3_02242	COG1309	transcriptional regulator
RSC3_02243	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC3_02244	COG3708	Transcriptional regulator
RSC3_02247	COG2378	regulation of single-species biofilm formation
RSC3_02249	COG0640	Transcriptional regulator
RSC3_02250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC3_02253	COG0531	amino acid
RSC3_02254	COG0741	lytic transglycosylase activity
RSC3_02255	COG1086	Polysaccharide biosynthesis protein
RSC3_02257	COG0438	transferase activity, transferring glycosyl groups
RSC3_02258	COG2322	membrane
RSC3_02262	COG1619	proteins homologs of microcin C7 resistance protein MccF
RSC3_02263	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC3_02264	COG3584	3D domain protein
RSC3_02264	COG1388	LysM domain
RSC3_02265	COG0514	ATP-dependent DNA helicase (RecQ)
RSC3_02269	COG2315	Protein conserved in bacteria
RSC3_02270	COG2427	Protein of unknown function (DUF1641)
RSC3_02271	COG3383	formate dehydrogenase (NAD+) activity
RSC3_02273	COG5444	nuclease activity
RSC3_02277	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
RSC3_02289	COG0402	S-adenosylhomocysteine deaminase activity
RSC3_02292	COG2267	carboxylic ester hydrolase activity
RSC3_02295	COG1280	lysine exporter protein (LysE YggA)
RSC3_02296	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RSC3_02298	COG0574	Belongs to the PEP-utilizing enzyme family
RSC3_02298	COG3848	Pyruvate phosphate dikinase
RSC3_02299	COG0574	Belongs to the PEP-utilizing enzyme family
RSC3_02299	COG3848	Pyruvate phosphate dikinase
RSC3_02303	COG2318	DinB family
RSC3_02304	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RSC3_02308	COG0156	8-amino-7-oxononanoate synthase activity
RSC3_02309	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RSC3_02312	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_02313	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_02315	COG2814	Major facilitator Superfamily
RSC3_02318	COG1657	PFAM Prenyltransferase squalene oxidase
RSC3_02319	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RSC3_02321	COG0733	neurotransmitter:sodium symporter activity
RSC3_02322	COG0733	neurotransmitter:sodium symporter activity
RSC3_02323	COG0385	Bile acid
RSC3_02324	COG0508	dehydrogenase complex catalyzes the overall conversion of
RSC3_02325	COG0567	Dehydrogenase, E1 component
RSC3_02326	COG4548	von Willebrand factor, type A
RSC3_02327	COG0714	Associated with various cellular activities
RSC3_02328	COG2032	superoxide dismutase activity
RSC3_02329	COG0791	NLP P60 protein
RSC3_02329	COG1388	LysM domain
RSC3_02331	COG0534	Mate efflux family protein
RSC3_02332	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RSC3_02333	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RSC3_02335	COG2962	Rard protein
RSC3_02336	COG2962	Rard protein
RSC3_02338	COG4305	rare lipoprotein A
RSC3_02340	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_02341	COG1733	regulation of RNA biosynthetic process
RSC3_02342	COG0778	Nitroreductase
RSC3_02343	COG0400	carboxylic ester hydrolase activity
RSC3_02345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC3_02346	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC3_02347	COG0793	Belongs to the peptidase S41A family
RSC3_02347	COG3409	Peptidoglycan-binding domain 1 protein
RSC3_02348	COG2226	methyltransferase
RSC3_02350	COG1876	peptidase activity
RSC3_02351	COG0813	purine-nucleoside phosphorylase activity
RSC3_02352	COG0701	Predicted permease
RSC3_02356	COG0671	phosphoesterase, PA-phosphatase related
RSC3_02360	COG4479	Belongs to the UPF0346 family
RSC3_02362	COG1509	lysine 2,3-aminomutase activity
RSC3_02363	COG1509	lysine 2,3-aminomutase activity
RSC3_02364	COG0456	acetyltransferase
RSC3_02365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RSC3_02366	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RSC3_02367	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RSC3_02368	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RSC3_02369	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RSC3_02372	COG0456	acetyltransferase
RSC3_02373	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RSC3_02374	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RSC3_02375	COG1846	Transcriptional regulator
RSC3_02377	COG3706	GGDEF domain
RSC3_02379	COG0534	Mate efflux family protein
RSC3_02382	COG4698	Protein conserved in bacteria
RSC3_02383	COG2755	lipolytic protein G-D-S-L family
RSC3_02384	COG1999	signal sequence binding
RSC3_02387	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RSC3_02390	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RSC3_02391	COG1272	protein, Hemolysin III
RSC3_02392	COG0204	Acyl-transferase
RSC3_02393	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RSC3_02394	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RSC3_02397	COG2136	Putative SAM-dependent methyltransferase
RSC3_02397	COG2521	methyltransferase
RSC3_02399	COG0129	dihydroxy-acid dehydratase activity
RSC3_02401	COG1413	lyase activity
RSC3_02402	COG1418	mRNA catabolic process
RSC3_02403	COG0386	Belongs to the glutathione peroxidase family
RSC3_02404	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RSC3_02405	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
RSC3_02406	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RSC3_02408	COG1278	Cold shock
RSC3_02412	COG0328	RNA-DNA hybrid ribonuclease activity
RSC3_02413	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RSC3_02414	COG0328	RNA-DNA hybrid ribonuclease activity
RSC3_02416	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RSC3_02419	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RSC3_02420	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RSC3_02422	COG1755	Isoprenylcysteine carboxyl methyltransferase
RSC3_02423	COG3424	synthase
RSC3_02424	COG3424	synthase
RSC3_02426	COG2233	PERMEase
RSC3_02427	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RSC3_02428	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
RSC3_02429	COG1199	ATP-dependent helicase activity
RSC3_02430	COG1199	ATP-dependent helicase activity
RSC3_02434	COG0116	Belongs to the methyltransferase superfamily
RSC3_02435	COG3599	regulation of cell shape
RSC3_02436	COG4474	Belongs to the UPF0398 family
RSC3_02439	COG3359	exonuclease
RSC3_02440	COG1111	helicase
RSC3_02440	COG1205	dead DEAH box helicase
RSC3_02441	COG2190	(PTS) system
RSC3_02442	COG0071	Belongs to the small heat shock protein (HSP20) family
RSC3_02449	COG3331	DNA recombination
RSC3_02450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RSC3_02450	COG4499	WXG100 protein secretion system (Wss), protein YukC
RSC3_02453	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RSC3_02454	COG3935	DnaD domain protein
RSC3_02455	COG0017	Asparaginyl-tRNA synthetase
RSC3_02456	COG0436	Aminotransferase
RSC3_02457	COG5353	protein conserved in bacteria
RSC3_02459	COG1199	ATP-dependent helicase activity
RSC3_02459	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RSC3_02460	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RSC3_02461	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RSC3_02462	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RSC3_02464	COG0617	tRNA 3'-terminal CCA addition
RSC3_02465	COG0438	transferase activity, transferring glycosyl groups
RSC3_02466	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RSC3_02467	COG1803	Methylglyoxal synthase
RSC3_02468	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RSC3_02469	COG1694	Mazg nucleotide pyrophosphohydrolase
RSC3_02470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC3_02472	COG4347	Protein of unknown function (DUF1405)
RSC3_02473	COG2010	Cytochrome c
RSC3_02473	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RSC3_02474	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RSC3_02475	COG0723	plastoquinol--plastocyanin reductase activity
RSC3_02477	COG5582	Belongs to the UPF0302 family
RSC3_02478	COG0457	Tetratricopeptide repeat
RSC3_02479	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RSC3_02480	COG0287	Prephenate dehydrogenase
RSC3_02481	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RSC3_02482	COG0159	tryptophan synthase activity
RSC3_02483	COG0133	tryptophan synthase activity
RSC3_02484	COG0135	phosphoribosylanthranilate isomerase activity
RSC3_02485	COG0134	indole-3-glycerol-phosphate synthase activity
RSC3_02486	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RSC3_02487	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RSC3_02488	COG4401	Chorismate mutase type I
RSC3_02489	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RSC3_02490	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RSC3_02491	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RSC3_02492	COG0105	UTP biosynthetic process
RSC3_02493	COG0142	geranyltranstransferase activity
RSC3_02494	COG2226	methyltransferase
RSC3_02495	COG0142	geranyltranstransferase activity
RSC3_02498	COG0776	regulation of translation
RSC3_02499	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RSC3_02503	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RSC3_02504	COG1160	GTP binding
RSC3_02509	COG1304	FMN binding
RSC3_02510	COG0539	negative regulation of cytoplasmic translation
RSC3_02511	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RSC3_02513	COG2959	enzyme of heme biosynthesis
RSC3_02514	COG3409	Peptidoglycan-binding domain 1 protein
RSC3_02514	COG3773	Cell wall hydrolase
RSC3_02515	COG2339	peptidase activity
RSC3_02518	COG0492	ferredoxin-NADP+ reductase activity
RSC3_02519	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RSC3_02520	COG4862	establishment of competence for transformation
RSC3_02521	COG1408	metallophosphoesterase
RSC3_02523	COG1388	LysM domain
RSC3_02524	COG1266	CAAX protease self-immunity
RSC3_02526	COG0514	ATP-dependent DNA helicase (RecQ)
RSC3_02527	COG4955	Helix-turn-helix domain
RSC3_02528	COG1141	Ferredoxin
RSC3_02529	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
RSC3_02530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RSC3_02531	COG0739	heme binding
RSC3_02533	COG1595	DNA-templated transcription, initiation
RSC3_02534	COG1316	TRANSCRIPTIONal
RSC3_02538	COG5002	protein histidine kinase activity
RSC3_02539	COG0745	RESPONSE REGULATOR receiver
RSC3_02540	COG5002	protein histidine kinase activity
RSC3_02541	COG0745	RESPONSE REGULATOR receiver
RSC3_02542	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RSC3_02543	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RSC3_02544	COG1333	cytochrome c biogenesis protein
RSC3_02545	COG1333	cytochrome c biogenesis protein
RSC3_02546	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC3_02547	COG1187	pseudouridine synthase activity
RSC3_02548	COG0700	Nucleoside recognition
RSC3_02549	COG2715	membrane protein required for spore maturation
RSC3_02550	COG1686	Belongs to the peptidase S11 family
RSC3_02551	COG1686	Belongs to the peptidase S11 family
RSC3_02553	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RSC3_02554	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RSC3_02556	COG1547	Domain of unknown function (DUF309)
RSC3_02557	COG0456	acetyltransferase
RSC3_02558	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RSC3_02559	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RSC3_02559	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RSC3_02560	COG0307	riboflavin synthase, alpha
RSC3_02561	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RSC3_02561	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RSC3_02565	COG0457	Tetratricopeptide repeat
RSC3_02566	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RSC3_02567	COG4086	secreted protein
RSC3_02568	COG4195	phage-related replication protein
RSC3_02569	COG0019	diaminopimelate decarboxylase activity
RSC3_02570	COG0019	diaminopimelate decarboxylase activity
RSC3_02572	COG0697	spore germination
RSC3_02574	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RSC3_02581	COG1686	Belongs to the peptidase S11 family
RSC3_02582	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RSC3_02583	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RSC3_02584	COG4974	Belongs to the 'phage' integrase family
RSC3_02586	COG0735	belongs to the Fur family
RSC3_02587	COG1300	Membrane
RSC3_02588	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC3_02589	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC3_02591	COG1953	Uracil, thiamine, allantoin
RSC3_02594	COG2153	protein acetylation
RSC3_02595	COG1379	DNA repair
RSC3_02596	COG0494	nUDIX hydrolase
RSC3_02598	COG1309	transcriptional regulator
RSC3_02600	COG0667	Aldo Keto reductase
RSC3_02602	COG1073	alpha beta
RSC3_02604	COG4918	Iron-sulphur cluster biosynthesis
RSC3_02606	COG0456	acetyltransferase
RSC3_02606	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RSC3_02607	COG2329	Antibiotic biosynthesis monooxygenase
RSC3_02608	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RSC3_02609	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RSC3_02611	COG0747	negative chemotaxis
RSC3_02612	COG0601	transmembrane transport
RSC3_02613	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSC3_02614	COG0444	Belongs to the ABC transporter superfamily
RSC3_02616	COG0534	Mate efflux family protein
RSC3_02620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RSC3_02622	COG2211	Major facilitator Superfamily
RSC3_02623	COG0346	lactoylglutathione lyase activity
RSC3_02624	COG1072	(Pantothenic acid kinase))
RSC3_02627	COG1126	abc transporter atp-binding protein
RSC3_02633	COG2205	protein histidine kinase activity
RSC3_02634	COG0745	RESPONSE REGULATOR receiver
RSC3_02645	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
RSC3_02646	COG2814	Major facilitator Superfamily
RSC3_02647	COG2814	Major facilitator Superfamily
RSC3_02649	COG4195	phage-related replication protein
RSC3_02650	COG0300	oxidoreductase activity
RSC3_02651	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC3_02652	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC3_02653	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RSC3_02654	COG4187	Peptidase family M20/M25/M40
RSC3_02655	COG4187	Peptidase family M20/M25/M40
RSC3_02656	COG1902	pentaerythritol trinitrate reductase activity
RSC3_02657	COG0596	Alpha beta hydrolase
RSC3_02658	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RSC3_02659	COG1234	tRNA 3'-trailer cleavage
RSC3_02660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RSC3_02663	COG2358	TRAP transporter, solute receptor (TAXI family
RSC3_02664	COG2188	Transcriptional regulator
RSC3_02665	COG2723	6-phospho-beta-galactosidase activity
RSC3_02666	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC3_02667	COG1447	Phosphotransferase system cellobiose-specific component IIA
RSC3_02668	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC3_02669	COG1785	Belongs to the alkaline phosphatase family
RSC3_02670	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_02671	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RSC3_02672	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RSC3_02674	COG0706	membrane insertase activity
RSC3_02675	COG2195	Cleaves the N-terminal amino acid of tripeptides
RSC3_02676	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RSC3_02677	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RSC3_02679	COG4129	membrane
RSC3_02680	COG1126	abc transporter atp-binding protein
RSC3_02681	COG0765	amino acid transport
RSC3_02682	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RSC3_02684	COG1597	lipid kinase activity
RSC3_02686	COG0508	dehydrogenase complex catalyzes the overall conversion of
RSC3_02687	COG0022	dehydrogenase e1 component
RSC3_02688	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RSC3_02689	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RSC3_02690	COG3426	butyrate kinase activity
RSC3_02692	COG0280	phosphate acetyltransferase
RSC3_02693	COG3290	protein histidine kinase activity
RSC3_02693	COG3829	transcription factor binding
RSC3_02695	COG0584	glycerophosphoryl diester phosphodiesterase
RSC3_02696	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSC3_02701	COG0745	RESPONSE REGULATOR receiver
RSC3_02702	COG0750	zinc metalloprotease
RSC3_02703	COG0497	DNA recombination
RSC3_02704	COG1438	arginine binding
RSC3_02705	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
RSC3_02706	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RSC3_02708	COG0142	geranyltranstransferase activity
RSC3_02709	COG1722	exodeoxyribonuclease VII activity
RSC3_02710	COG1570	exodeoxyribonuclease VII activity
RSC3_02711	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RSC3_02712	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RSC3_02713	COG1302	Protein conserved in bacteria
RSC3_02714	COG0439	Biotin carboxylase
RSC3_02715	COG0511	ligase activity, forming carbon-carbon bonds
RSC3_02723	COG3854	ATPases associated with a variety of cellular activities
RSC3_02726	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RSC3_02727	COG0006	proline dipeptidase activity
RSC3_02728	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RSC3_02730	COG3872	metal-dependent enzyme
RSC3_02732	COG1752	Esterase of the alpha-beta hydrolase superfamily
RSC3_02733	COG1321	iron dependent repressor
RSC3_02734	COG0095	Lipoate-protein ligase
RSC3_02735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RSC3_02736	COG2113	Glycine betaine
RSC3_02737	COG4176	ABC-type proline glycine betaine transport system permease component
RSC3_02738	COG0517	IMP dehydrogenase activity
RSC3_02738	COG4175	Glycine betaine
RSC3_02739	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RSC3_02740	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RSC3_02741	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RSC3_02742	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RSC3_02743	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RSC3_02748	COG0681	Belongs to the peptidase S26 family
RSC3_02753	COG4940	Competence protein ComGF
RSC3_02755	COG4970	Tfp pilus assembly protein FimT
RSC3_02756	COG4537	Required for transformation and DNA binding
RSC3_02757	COG1459	type II secretion system
RSC3_02758	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RSC3_02759	COG1366	Belongs to the anti-sigma-factor antagonist family
RSC3_02760	COG1393	Belongs to the ArsC family
RSC3_02762	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC3_02764	COG0011	TIGRFAM Protein of
RSC3_02766	COG2866	Carboxypeptidase
RSC3_02768	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC3_02769	COG1368	sulfuric ester hydrolase activity
RSC3_02770	COG1940	carbohydrate kinase activity
RSC3_02771	COG4483	Protein conserved in bacteria
RSC3_02772	COG0697	spore germination
RSC3_02773	COG0697	spore germination
RSC3_02774	COG0457	Tetratricopeptide repeat
RSC3_02774	COG0705	Rhomboid family
RSC3_02776	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RSC3_02777	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RSC3_02779	COG0438	transferase activity, transferring glycosyl groups
RSC3_02781	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RSC3_02782	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RSC3_02785	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RSC3_02786	COG1131	(ABC) transporter
RSC3_02791	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RSC3_02792	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RSC3_02793	COG0581	inorganic phosphate transmembrane transporter activity
RSC3_02794	COG0573	inorganic phosphate transmembrane transporter activity
RSC3_02795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RSC3_02796	COG0768	penicillin binding
RSC3_02797	COG0477	Major facilitator Superfamily
RSC3_02798	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RSC3_02799	COG2839	Protein conserved in bacteria
RSC3_02800	COG5521	maltodextrose utilization protein MalA
RSC3_02801	COG1388	LysM domain
RSC3_02802	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RSC3_02803	COG4709	membrane
RSC3_02804	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
RSC3_02805	COG0735	belongs to the Fur family
RSC3_02806	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RSC3_02807	COG1121	(ABC) transporter
RSC3_02808	COG1121	(ABC) transporter
RSC3_02809	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC3_02811	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
RSC3_02812	COG0513	Belongs to the DEAD box helicase family
RSC3_02814	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RSC3_02815	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RSC3_02816	COG2384	SAM-dependent methyltransferase
RSC3_02822	COG5444	nuclease activity
RSC3_02825	COG2010	Cytochrome c
RSC3_02826	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RSC3_02828	COG0358	DNA primase activity
RSC3_02829	COG1671	Belongs to the UPF0178 family
RSC3_02830	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RSC3_02831	COG0517	IMP dehydrogenase activity
RSC3_02832	COG0751	glycine-tRNA ligase activity
RSC3_02833	COG0752	glycyl-tRNA synthetase alpha subunit
RSC3_02834	COG1381	Involved in DNA repair and RecF pathway recombination
RSC3_02836	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RSC3_02837	COG0295	cytidine deaminase activity
RSC3_02838	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
RSC3_02839	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RSC3_02840	COG1480	7TM receptor with intracellular HD hydrolase
RSC3_02841	COG1702	phosphate starvation-inducible protein PhoH
RSC3_02842	COG0561	phosphatase activity
RSC3_02845	COG4864	UPF0365 protein
RSC3_02846	COG1030	water channel activity
RSC3_02847	COG1610	YqeY-like protein
RSC3_02848	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RSC3_02849	COG1283	sodium-dependent phosphate transmembrane transporter activity
RSC3_02850	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RSC3_02851	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RSC3_02852	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RSC3_02853	COG2264	protein methyltransferase activity
RSC3_02854	COG0484	heat shock protein binding
RSC3_02855	COG0484	heat shock protein binding
RSC3_02856	COG0443	Heat shock 70 kDa protein
RSC3_02857	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RSC3_02858	COG1420	regulation of RNA biosynthetic process
RSC3_02859	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RSC3_02860	COG0481	GTPase activity
RSC3_02862	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSC3_02863	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RSC3_02864	COG0268	Binds directly to 16S ribosomal RNA
RSC3_02865	COG1733	regulation of RNA biosynthetic process
RSC3_02866	COG2249	NAD(P)H dehydrogenase (quinone) activity
RSC3_02867	COG1466	dna polymerase III delta subunit
RSC3_02868	COG1466	dna polymerase III delta subunit
RSC3_02870	COG0658	competence protein
RSC3_02870	COG2333	competence protein COMEC
RSC3_02871	COG0658	competence protein
RSC3_02871	COG2333	competence protein COMEC
RSC3_02872	COG2131	deaminase
RSC3_02873	COG1555	photosystem II stabilization
RSC3_02873	COG1596	polysaccharide export
RSC3_02875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RSC3_02876	COG2226	methyltransferase
RSC3_02877	COG0799	negative regulation of ribosome biogenesis
RSC3_02878	COG1713	HD superfamily hydrolase involved in NAD metabolism
RSC3_02879	COG1713	HD superfamily hydrolase involved in NAD metabolism
RSC3_02880	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RSC3_02881	COG1534	Rna-binding protein
RSC3_02882	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RSC3_02883	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RSC3_02884	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RSC3_02885	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RSC3_02888	COG2755	lipolytic protein G-D-S-L family
RSC3_02892	COG5609	conserved protein (DUF2294)
RSC3_02893	COG3383	formate dehydrogenase (NAD+) activity
RSC3_02894	COG2427	Protein of unknown function (DUF1641)
RSC3_02903	COG3223	Belongs to the PsiE family
RSC3_02904	COG0642	Histidine kinase
RSC3_02904	COG5002	protein histidine kinase activity
RSC3_02905	COG0745	RESPONSE REGULATOR receiver
RSC3_02906	COG0745	RESPONSE REGULATOR receiver
RSC3_02907	COG2311	Membrane
RSC3_02908	COG0454	-acetyltransferase
RSC3_02913	COG1247	-acetyltransferase
RSC3_02915	COG0561	phosphatase activity
RSC3_02916	COG0561	phosphatase activity
RSC3_02917	COG1486	melibiose metabolic process
RSC3_02921	COG0789	Transcriptional regulator
RSC3_02921	COG4978	Transcriptional regulator
RSC3_02924	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RSC3_02926	COG2828	Protein conserved in bacteria
RSC3_02928	COG2181	nitrate reductase activity
RSC3_02929	COG2181	nitrate reductase activity
RSC3_02930	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RSC3_02931	COG1140	nitrate reductase beta subunit
RSC3_02932	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RSC3_02933	COG2223	nitrite transmembrane transporter activity
RSC3_02936	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RSC3_02937	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC3_02940	COG4585	Histidine kinase
RSC3_02941	COG0730	response to heat
RSC3_02942	COG0425	Belongs to the sulfur carrier protein TusA family
RSC3_02943	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RSC3_02943	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC3_02944	COG0425	Belongs to the sulfur carrier protein TusA family
RSC3_02944	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RSC3_02945	COG2210	Belongs to the sulfur carrier protein TusA family
RSC3_02946	COG1937	Protein conserved in bacteria
RSC3_02949	COG0113	porphobilinogen synthase activity
RSC3_02951	COG1942	4-Oxalocrotonate Tautomerase
RSC3_02952	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RSC3_02953	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RSC3_02954	COG1733	regulation of RNA biosynthetic process
RSC3_02955	COG3239	Fatty acid desaturase
RSC3_02956	COG4585	Histidine kinase
RSC3_02957	COG2197	response regulator
RSC3_02958	COG0492	ferredoxin-NADP+ reductase activity
RSC3_02960	COG0747	negative chemotaxis
RSC3_02961	COG0747	negative chemotaxis
RSC3_02962	COG0601	transmembrane transport
RSC3_02963	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSC3_02965	COG0444	Belongs to the ABC transporter superfamily
RSC3_02967	COG4608	Belongs to the ABC transporter superfamily
RSC3_02971	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_02973	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
RSC3_02976	COG2124	cytochrome p450
RSC3_02977	COG2124	cytochrome p450
RSC3_02978	COG3507	Belongs to the glycosyl hydrolase 43 family
RSC3_02979	COG2211	Major facilitator Superfamily
RSC3_02981	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_02982	COG1621	beta-fructofuranosidase activity
RSC3_02983	COG1621	beta-fructofuranosidase activity
RSC3_02984	COG3716	PTS system mannose fructose sorbose family IID component
RSC3_02985	COG3715	PTS system
RSC3_02986	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC3_02987	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC3_02988	COG3933	PFAM sigma-54 factor interaction domain-containing protein
RSC3_02988	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RSC3_02989	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RSC3_02989	COG3933	PFAM sigma-54 factor interaction domain-containing protein
RSC3_02990	COG3933	PFAM sigma-54 factor interaction domain-containing protein
RSC3_02990	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RSC3_02995	COG2169	Transcriptional regulator
RSC3_02996	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RSC3_02997	COG2205	protein histidine kinase activity
RSC3_02999	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
RSC3_03002	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RSC3_03003	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RSC3_03006	COG0656	L-ascorbic acid biosynthetic process
RSC3_03007	COG2814	Major facilitator Superfamily
RSC3_03008	COG1733	regulation of RNA biosynthetic process
RSC3_03009	COG3340	Belongs to the peptidase S51 family
RSC3_03010	COG1587	Uroporphyrinogen-III synthase
RSC3_03013	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC3_03015	COG2814	Major facilitator Superfamily
RSC3_03016	COG2814	Major facilitator Superfamily
RSC3_03018	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RSC3_03018	COG2124	cytochrome p450
RSC3_03019	COG1309	transcriptional regulator
RSC3_03021	COG1404	Belongs to the peptidase S8 family
RSC3_03022	COG2226	methyltransferase
RSC3_03028	COG0626	cystathionine gamma-synthase activity
RSC3_03029	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RSC3_03030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RSC3_03031	COG2226	methyltransferase
RSC3_03034	COG0768	penicillin binding
RSC3_03035	COG0768	penicillin binding
RSC3_03036	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RSC3_03037	COG0572	uridine kinase
RSC3_03038	COG0826	peptidase U32
RSC3_03039	COG0826	peptidase U32
RSC3_03040	COG4122	O-methyltransferase activity
RSC3_03041	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RSC3_03042	COG3906	Belongs to the UPF0473 family
RSC3_03043	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RSC3_03044	COG4472	Bacterial protein of unknown function (DUF965)
RSC3_03045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RSC3_03046	COG0628	permease
RSC3_03049	COG3881	PFAM PRC-barrel domain
RSC3_03050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RSC3_03051	COG0457	Tetratricopeptide repeat
RSC3_03052	COG0482	sulfurtransferase activity
RSC3_03053	COG1104	cysteine desulfurase activity
RSC3_03054	COG1959	2 iron, 2 sulfur cluster binding
RSC3_03055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RSC3_03056	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RSC3_03057	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RSC3_03058	COG0124	histidyl-tRNA synthetase
RSC3_03060	COG4991	sh3 domain protein
RSC3_03060	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSC3_03060	COG3103	Sh3 type 3 domain protein
RSC3_03061	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSC3_03061	COG3103	Sh3 type 3 domain protein
RSC3_03061	COG4991	sh3 domain protein
RSC3_03062	COG1490	D-aminoacyl-tRNA deacylase activity
RSC3_03063	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RSC3_03064	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RSC3_03065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RSC3_03065	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RSC3_03066	COG5416	Lipopolysaccharide assembly protein A domain
RSC3_03067	COG0490	domain, Protein
RSC3_03068	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RSC3_03068	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RSC3_03070	COG2244	polysaccharide biosynthetic process
RSC3_03071	COG2323	membrane
RSC3_03073	COG1862	Preprotein translocase
RSC3_03074	COG0343	queuine tRNA-ribosyltransferase activity
RSC3_03075	COG0343	queuine tRNA-ribosyltransferase activity
RSC3_03076	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RSC3_03078	COG2255	four-way junction helicase activity
RSC3_03079	COG0632	four-way junction helicase activity
RSC3_03081	COG2112	serine threonine protein kinase
RSC3_03085	COG0642	Histidine kinase
RSC3_03086	COG0745	RESPONSE REGULATOR receiver
RSC3_03088	COG2318	DinB family
RSC3_03089	COG4195	phage-related replication protein
RSC3_03092	COG0217	transcriptional regulatory protein
RSC3_03094	COG1388	LysM domain
RSC3_03095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RSC3_03096	COG0157	Belongs to the NadC ModD family
RSC3_03097	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RSC3_03098	COG1104	cysteine desulfurase activity
RSC3_03099	COG1104	cysteine desulfurase activity
RSC3_03100	COG1827	regulation of RNA biosynthetic process
RSC3_03101	COG0077	Prephenate dehydratase
RSC3_03102	COG4492	Belongs to the UPF0735 family
RSC3_03103	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RSC3_03105	COG3290	protein histidine kinase activity
RSC3_03106	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RSC3_03107	COG2868	ribosomal protein
RSC3_03108	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RSC3_03109	COG1994	Peptidase M50
RSC3_03110	COG0739	heme binding
RSC3_03111	COG3832	glyoxalase III activity
RSC3_03113	COG2894	cell division
RSC3_03114	COG0850	regulation of cytokinetic process
RSC3_03115	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
RSC3_03117	COG1077	Cell shape determining protein MreB Mrl
RSC3_03118	COG2003	Belongs to the UPF0758 family
RSC3_03119	COG0424	maF-like protein
RSC3_03122	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RSC3_03123	COG0285	dihydrofolate synthase activity
RSC3_03124	COG0525	valine-tRNA ligase activity
RSC3_03126	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RSC3_03127	COG1388	LysM domain
RSC3_03128	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RSC3_03129	COG0113	porphobilinogen synthase activity
RSC3_03130	COG1587	Uroporphyrinogen-III synthase
RSC3_03131	COG0181	hydroxymethylbilane synthase activity
RSC3_03132	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RSC3_03133	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RSC3_03135	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RSC3_03136	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RSC3_03137	COG0470	DNA polymerase III
RSC3_03137	COG1067	ATP-dependent peptidase activity
RSC3_03139	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RSC3_03140	COG0544	peptidyl-prolyl cis-trans isomerase activity
RSC3_03141	COG0457	Tetratricopeptide repeat
RSC3_03141	COG1477	protein flavinylation
RSC3_03142	COG0066	3-isopropylmalate dehydratase activity
RSC3_03143	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RSC3_03144	COG0473	3-isopropylmalate dehydrogenase activity
RSC3_03145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RSC3_03146	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RSC3_03147	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RSC3_03148	COG0440	acetolactate synthase activity
RSC3_03149	COG0028	Belongs to the TPP enzyme family
RSC3_03150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RSC3_03152	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RSC3_03156	COG0622	Phosphoesterase
RSC3_03157	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RSC3_03158	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RSC3_03159	COG5401	PFAM Sporulation and spore germination
RSC3_03160	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RSC3_03161	COG1846	Transcriptional regulator
RSC3_03162	COG2197	response regulator
RSC3_03163	COG4221	oxidoreductase activity
RSC3_03164	COG0824	Thioesterase
RSC3_03165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RSC3_03166	COG1053	succinate dehydrogenase
RSC3_03167	COG1053	succinate dehydrogenase
RSC3_03168	COG1053	succinate dehydrogenase
RSC3_03169	COG2009	succinate dehydrogenase
RSC3_03170	COG1719	4-vinyl reductase, 4VR
RSC3_03171	COG0527	aspartate kinase activity
RSC3_03172	COG0322	excinuclease ABC activity
RSC3_03173	COG3118	belongs to the thioredoxin family
RSC3_03174	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RSC3_03175	COG2086	electron transfer activity
RSC3_03176	COG1024	Enoyl-CoA hydratase
RSC3_03177	COG1309	transcriptional regulator
RSC3_03178	COG0318	PFAM AMP-dependent synthetase and ligase
RSC3_03179	COG0318	PFAM AMP-dependent synthetase and ligase
RSC3_03180	COG3766	membrane
RSC3_03181	COG1193	negative regulation of DNA recombination
RSC3_03182	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RSC3_03182	COG1796	DNA polymerase
RSC3_03183	COG1286	toxin biosynthetic process
RSC3_03184	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
RSC3_03185	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RSC3_03190	COG0072	phenylalanine-tRNA ligase activity
RSC3_03190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RSC3_03191	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RSC3_03192	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RSC3_03194	COG1966	Carbon starvation protein
RSC3_03195	COG1966	Carbon starvation protein
RSC3_03196	COG1309	transcriptional regulator
RSC3_03197	COG3402	PFAM membrane-flanked domain
RSC3_03201	COG0395	ABC-type sugar transport system, permease component
RSC3_03202	COG1175	transmembrane transport
RSC3_03203	COG1653	transport
RSC3_03204	COG0371	Dehydrogenase
RSC3_03205	COG0235	Class ii aldolase
RSC3_03206	COG1069	ribulokinase activity
RSC3_03207	COG2160	L-arabinose isomerase activity
RSC3_03208	COG3507	Belongs to the glycosyl hydrolase 43 family
RSC3_03209	COG1363	Peptidase, m42
RSC3_03211	COG3326	Membrane
RSC3_03212	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RSC3_03213	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RSC3_03214	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RSC3_03215	COG1346	cytolysis
RSC3_03217	COG3540	Alkaline phosphatase
RSC3_03218	COG3279	Response regulator of the LytR AlgR family
RSC3_03219	COG3275	phosphorelay sensor kinase activity
RSC3_03221	COG1011	Hydrolase
RSC3_03222	COG1011	Hydrolase
RSC3_03224	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RSC3_03226	COG0398	Pfam SNARE associated Golgi protein
RSC3_03227	COG1484	DNA-dependent DNA replication
RSC3_03228	COG3611	Membrane attachment protein
RSC3_03229	COG3611	Membrane attachment protein
RSC3_03230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RSC3_03232	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RSC3_03233	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RSC3_03235	COG3866	Pectate lyase
RSC3_03236	COG0237	dephospho-CoA kinase activity
RSC3_03237	COG1971	Probably functions as a manganese efflux pump
RSC3_03238	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RSC3_03239	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RSC3_03239	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RSC3_03240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RSC3_03240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RSC3_03241	COG5002	protein histidine kinase activity
RSC3_03242	COG0745	RESPONSE REGULATOR receiver
RSC3_03243	COG0039	L-malate dehydrogenase activity
RSC3_03244	COG0538	isocitrate dehydrogenase activity
RSC3_03245	COG0538	isocitrate dehydrogenase activity
RSC3_03246	COG0372	Belongs to the citrate synthase family
RSC3_03248	COG2273	Hydrolase Family 16
RSC3_03250	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RSC3_03251	COG2707	UPF0756 membrane protein
RSC3_03252	COG0628	permease
RSC3_03253	COG3030	protein affecting phage T7 exclusion by the F plasmid
RSC3_03255	COG0205	6-phosphofructokinase activity
RSC3_03256	COG0825	malonyl-CoA metabolic process
RSC3_03257	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RSC3_03258	COG0281	malic enzyme
RSC3_03259	COG0587	DNA-directed DNA polymerase activity
RSC3_03263	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RSC3_03265	COG4109	DRTGG domain
RSC3_03266	COG4109	DRTGG domain
RSC3_03267	COG1695	Transcriptional regulator
RSC3_03268	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RSC3_03269	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_03271	COG0165	Argininosuccinate lyase
RSC3_03272	COG0137	argininosuccinate synthase activity
RSC3_03273	COG0521	Mo-molybdopterin cofactor biosynthetic process
RSC3_03274	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RSC3_03275	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RSC3_03276	COG0827	DNA restriction-modification system
RSC3_03277	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
RSC3_03278	COG3874	Sporulation protein YtfJ
RSC3_03280	COG1714	RDD family
RSC3_03281	COG0616	signal peptide processing
RSC3_03282	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RSC3_03284	COG1846	Transcriptional regulator
RSC3_03285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RSC3_03287	COG0301	tRNA thio-modification
RSC3_03288	COG1104	cysteine desulfurase activity
RSC3_03289	COG1114	Component of the transport system for branched-chain amino acids
RSC3_03290	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
RSC3_03291	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RSC3_03292	COG1309	transcriptional regulator
RSC3_03293	COG1956	GAF domain-containing protein
RSC3_03294	COG2199	diguanylate cyclase activity
RSC3_03294	COG2203	Gaf domain
RSC3_03295	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RSC3_03298	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RSC3_03299	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RSC3_03300	COG0454	-acetyltransferase
RSC3_03301	COG0517	IMP dehydrogenase activity
RSC3_03302	COG0123	including yeast histone deacetylase and acetoin utilization protein
RSC3_03303	COG1360	Flagellar Motor Protein
RSC3_03304	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RSC3_03305	COG1609	Transcriptional regulator
RSC3_03306	COG1605	Chorismate mutase
RSC3_03306	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RSC3_03308	COG3118	belongs to the thioredoxin family
RSC3_03309	COG4980	gas vesicle protein
RSC3_03310	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
RSC3_03311	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RSC3_03313	COG1674	ftsk spoiiie
RSC3_03314	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RSC3_03315	COG4848	Belongs to the UPF0354 family
RSC3_03316	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC3_03318	COG1363	Peptidase, m42
RSC3_03319	COG5584	Small secreted protein
RSC3_03320	COG0281	malic enzyme
RSC3_03321	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RSC3_03322	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RSC3_03324	COG0510	thiamine kinase activity
RSC3_03325	COG1523	belongs to the glycosyl hydrolase 13 family
RSC3_03326	COG1597	lipid kinase activity
RSC3_03328	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RSC3_03329	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RSC3_03331	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RSC3_03332	COG2252	PERMEase
RSC3_03333	COG4473	ABC transporter
RSC3_03334	COG1131	(ABC) transporter
RSC3_03335	COG1349	DNA-binding transcription factor activity
RSC3_03336	COG1187	pseudouridine synthase activity
RSC3_03337	COG2244	polysaccharide biosynthetic process
RSC3_03338	COG2081	HI0933 family
RSC3_03339	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RSC3_03341	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RSC3_03342	COG0457	Tetratricopeptide repeat
RSC3_03345	COG5578	integral membrane protein
RSC3_03346	COG0673	inositol 2-dehydrogenase activity
RSC3_03347	COG1653	transport
RSC3_03348	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RSC3_03349	COG4209	transmembrane transport
RSC3_03350	COG2207	Transcriptional regulator
RSC3_03351	COG1653	transport
RSC3_03352	COG0395	ABC-type sugar transport system, permease component
RSC3_03353	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RSC3_03354	COG1073	alpha beta
RSC3_03356	COG0583	DNA-binding transcription factor activity
RSC3_03357	COG0346	lactoylglutathione lyase activity
RSC3_03358	COG0495	leucyl-tRNA aminoacylation
RSC3_03360	COG2814	Major facilitator Superfamily
RSC3_03361	COG1464	Belongs to the NlpA lipoprotein family
RSC3_03362	COG2433	Pfam Transposase IS66
RSC3_03363	COG0577	efflux transmembrane transporter activity
RSC3_03364	COG1136	(ABC) transporter
RSC3_03366	COG1131	(ABC) transporter
RSC3_03367	COG1725	Transcriptional regulator
RSC3_03370	COG1242	4 iron, 4 sulfur cluster binding
RSC3_03371	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RSC3_03372	COG1301	dicarboxylic acid transport
RSC3_03374	COG2267	carboxylic ester hydrolase activity
RSC3_03375	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RSC3_03376	COG0671	phosphoesterase, PA-phosphatase related
RSC3_03377	COG0438	transferase activity, transferring glycosyl groups
RSC3_03377	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RSC3_03378	COG0367	asparagine synthase
RSC3_03379	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RSC3_03380	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
RSC3_03381	COG1301	dicarboxylic acid transport
RSC3_03384	COG1506	peptidase
RSC3_03385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RSC3_03386	COG1116	anion transmembrane transporter activity
RSC3_03387	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RSC3_03388	COG0494	nUDIX hydrolase
RSC3_03390	COG4824	toxin secretion phage lysis holin
RSC3_03391	COG0783	Belongs to the Dps family
RSC3_03394	COG1854	S-ribosylhomocysteine lyase activity
RSC3_03395	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RSC3_03396	COG0288	reversible hydration of carbon dioxide
RSC3_03397	COG0523	cobalamin synthesis protein
RSC3_03398	COG0803	Belongs to the bacterial solute-binding protein 9 family
RSC3_03400	COG0254	rRNA binding
RSC3_03402	COG1271	oxidase subunit
RSC3_03403	COG1294	oxidase, subunit
RSC3_03406	COG4948	Mandelate Racemase Muconate Lactonizing
RSC3_03407	COG4948	Mandelate Racemase Muconate Lactonizing
RSC3_03408	COG0318	PFAM AMP-dependent synthetase and ligase
RSC3_03409	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RSC3_03410	COG0596	Alpha beta hydrolase
RSC3_03411	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
RSC3_03412	COG1169	isochorismate synthase
RSC3_03413	COG1575	Belongs to the MenA family. Type 1 subfamily
RSC3_03414	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RSC3_03415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RSC3_03416	COG0058	SHG alpha-glucan phosphorylase activity
RSC3_03417	COG0297	glycogen (starch) synthase activity
RSC3_03418	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RSC3_03419	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RSC3_03420	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RSC3_03426	COG1609	Transcriptional regulator
RSC3_03427	COG3859	Proton-coupled thiamine transporter YuaJ
RSC3_03428	COG3764	Sortase (surface protein transpeptidase)
RSC3_03431	COG0457	Tetratricopeptide repeat
RSC3_03433	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
RSC3_03434	COG0569	domain protein
RSC3_03435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RSC3_03437	COG2318	DinB family
RSC3_03439	COG1454	alcohol dehydrogenase
RSC3_03440	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_03441	COG1510	regulation of RNA biosynthetic process
RSC3_03443	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RSC3_03444	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RSC3_03445	COG2140	Oxalate decarboxylase
RSC3_03446	COG1397	ADP-ribosylglycohydrolase
RSC3_03457	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
RSC3_03461	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RSC3_03462	COG0726	polysaccharide deacetylase
RSC3_03463	COG1408	metallophosphoesterase
RSC3_03464	COG1968	undecaprenyl-diphosphatase activity
RSC3_03465	COG0628	permease
RSC3_03466	COG0673	inositol 2-dehydrogenase activity
RSC3_03467	COG0673	inositol 2-dehydrogenase activity
RSC3_03468	COG0693	protein deglycase activity
RSC3_03469	COG0840	transmembrane signaling receptor activity
RSC3_03470	COG0840	transmembrane signaling receptor activity
RSC3_03471	COG0840	transmembrane signaling receptor activity
RSC3_03474	COG2070	2-Nitropropane dioxygenase
RSC3_03475	COG0432	Pfam Uncharacterised protein family UPF0047
RSC3_03476	COG0366	Alpha amylase catalytic
RSC3_03477	COG0366	Alpha amylase catalytic
RSC3_03480	COG5297	Belongs to the glycosyl hydrolase family 6
RSC3_03481	COG1253	flavin adenine dinucleotide binding
RSC3_03482	COG2738	Putative neutral zinc metallopeptidase
RSC3_03485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RSC3_03487	COG2323	membrane
RSC3_03488	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
RSC3_03491	COG0166	Belongs to the GPI family
RSC3_03493	COG1979	alcohol dehydrogenase
RSC3_03494	COG2155	Conserved Protein
RSC3_03495	COG1098	S1 RNA binding domain
RSC3_03496	COG0436	Aminotransferase
RSC3_03497	COG1522	sequence-specific DNA binding
RSC3_03498	COG2267	carboxylic ester hydrolase activity
RSC3_03499	COG2267	carboxylic ester hydrolase activity
RSC3_03503	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RSC3_03506	COG5018	Exonuclease
RSC3_03507	COG2814	Major facilitator Superfamily
RSC3_03508	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RSC3_03509	COG3011	Protein conserved in bacteria
RSC3_03511	COG3290	protein histidine kinase activity
RSC3_03512	COG4565	transcriptional regulatory protein
RSC3_03513	COG1183	phosphatidylcholine synthase activity
RSC3_03514	COG0586	Pfam SNARE associated Golgi protein
RSC3_03515	COG0688	phosphatidylethanolamine metabolic process
RSC3_03516	COG3493	citrate carrier protein
RSC3_03517	COG3493	citrate carrier protein
RSC3_03519	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RSC3_03519	COG2111	Na H antiporter
RSC3_03520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RSC3_03520	COG2111	Na H antiporter
RSC3_03521	COG2111	Na H antiporter
RSC3_03522	COG1006	Multisubunit Na H antiporter MnhC subunit
RSC3_03523	COG0651	ATP synthesis coupled electron transport
RSC3_03524	COG1863	multisubunit Na H antiporter MnhE subunit
RSC3_03525	COG2212	antiporter activity
RSC3_03526	COG1320	monovalent cation:proton antiporter activity
RSC3_03527	COG2050	protein possibly involved in aromatic compounds catabolism
RSC3_03528	COG2197	response regulator
RSC3_03529	COG4585	Histidine kinase
RSC3_03530	COG4585	Histidine kinase
RSC3_03532	COG0142	geranyltranstransferase activity
RSC3_03534	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
RSC3_03535	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RSC3_03536	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RSC3_03537	COG1335	isochorismatase
RSC3_03538	COG5506	Protein of unknown function (DUF1694)
RSC3_03541	COG0628	permease
RSC3_03543	COG1418	mRNA catabolic process
RSC3_03544	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_03547	COG1511	domain protein
RSC3_03548	COG0433	COG0433 Predicted ATPase
RSC3_03548	COG1674	ftsk spoiiie
RSC3_03549	COG4499	WXG100 protein secretion system (Wss), protein YukC
RSC3_03550	COG4499	WXG100 protein secretion system (Wss), protein YukC
RSC3_03551	COG5417	Belongs to the EsaB family
RSC3_03552	COG4842	Belongs to the WXG100 family
RSC3_03553	COG1115	amino acid carrier protein
RSC3_03554	COG2508	Transcriptional regulator
RSC3_03554	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RSC3_03555	COG0686	Belongs to the AlaDH PNT family
RSC3_03557	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RSC3_03559	COG1268	BioY protein
RSC3_03560	COG2056	Na+-H+ antiporter family
RSC3_03561	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RSC3_03562	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
RSC3_03564	COG3584	3D domain protein
RSC3_03567	COG1252	NADH dehydrogenase
RSC3_03568	COG0492	ferredoxin-NADP+ reductase activity
RSC3_03571	COG0454	-acetyltransferase
RSC3_03572	COG0316	Belongs to the HesB IscA family
RSC3_03573	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RSC3_03574	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RSC3_03575	COG4844	belongs to the
RSC3_03576	COG1252	NADH dehydrogenase
RSC3_03577	COG5646	InterPro IPR014922
RSC3_03580	COG0457	Tetratricopeptide repeat
RSC3_03581	COG3479	Phenolic acid decarboxylase
RSC3_03583	COG4837	Protein of unknown function (DUF1462)
RSC3_03584	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RSC3_03585	COG0823	Involved in the tonB-independent uptake of proteins
RSC3_03585	COG1506	peptidase
RSC3_03585	COG4946	Tricorn protease homolog
RSC3_03586	COG0823	Involved in the tonB-independent uptake of proteins
RSC3_03586	COG1506	peptidase
RSC3_03586	COG4946	Tricorn protease homolog
RSC3_03587	COG0083	homoserine kinase activity
RSC3_03588	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RSC3_03589	COG0460	homoserine dehydrogenase
RSC3_03590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RSC3_03591	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RSC3_03592	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RSC3_03593	COG0647	UMP catabolic process
RSC3_03594	COG2445	Protein of unknown function DUF86
RSC3_03595	COG4470	Protein conserved in bacteria
RSC3_03598	COG0739	heme binding
RSC3_03600	COG0733	neurotransmitter:sodium symporter activity
RSC3_03602	COG3377	Domain of unknown function (DUF1805)
RSC3_03603	COG0737	Belongs to the 5'-nucleotidase family
RSC3_03604	COG0730	response to heat
RSC3_03605	COG1801	Protein of unknown function DUF72
RSC3_03607	COG3226	Transcriptional regulator
RSC3_03609	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RSC3_03610	COG2508	Transcriptional regulator
RSC3_03611	COG2814	Major facilitator Superfamily
RSC3_03612	COG1288	antiporter activity
RSC3_03614	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RSC3_03615	COG2356	endonuclease I
RSC3_03617	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RSC3_03622	COG0457	Tetratricopeptide repeat
RSC3_03624	COG0719	Fe-S assembly protein
RSC3_03625	COG0822	iron-sulfur transferase activity
RSC3_03626	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RSC3_03627	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RSC3_03628	COG0719	Fe-S assembly protein
RSC3_03629	COG0396	ATPase activity
RSC3_03631	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RSC3_03632	COG1464	Belongs to the NlpA lipoprotein family
RSC3_03633	COG2011	ABC-type metal ion transport system permease component
RSC3_03634	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RSC3_03636	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSC3_03637	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RSC3_03639	COG0509	glycine decarboxylation via glycine cleavage system
RSC3_03640	COG0509	glycine decarboxylation via glycine cleavage system
RSC3_03641	COG1393	Belongs to the ArsC family
RSC3_03642	COG1960	acyl-CoA dehydrogenase activity
RSC3_03643	COG0183	Belongs to the thiolase family
RSC3_03644	COG1024	Enoyl-CoA hydratase
RSC3_03644	COG1250	3-hydroxyacyl-CoA dehydrogenase
RSC3_03647	COG5577	PFAM Coat F domain
RSC3_03650	COG1120	ATPase activity
RSC3_03651	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_03652	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_03653	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_03654	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC3_03658	COG1686	Belongs to the peptidase S11 family
RSC3_03659	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_03660	COG0783	Belongs to the Dps family
RSC3_03661	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RSC3_03662	COG0745	RESPONSE REGULATOR receiver
RSC3_03663	COG2205	protein histidine kinase activity
RSC3_03663	COG2770	Histidine kinase
RSC3_03665	COG1309	transcriptional regulator
RSC3_03666	COG0114	fumarate hydratase activity
RSC3_03668	COG0697	spore germination
RSC3_03669	COG0814	amino acid
RSC3_03672	COG2197	response regulator
RSC3_03673	COG4585	Histidine kinase
RSC3_03674	COG4758	membrane
RSC3_03675	COG3595	metallopeptidase activity
RSC3_03676	COG1842	Phage shock protein A
RSC3_03677	COG1842	Phage shock protein A
RSC3_03678	COG4758	membrane
RSC3_03679	COG4677	pectinesterase activity
RSC3_03680	COG2096	Adenosyltransferase
RSC3_03681	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_03682	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RSC3_03683	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RSC3_03686	COG1454	alcohol dehydrogenase
RSC3_03687	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RSC3_03688	COG1120	ATPase activity
RSC3_03689	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_03690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC3_03691	COG1802	Transcriptional regulator
RSC3_03693	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_03694	COG2258	MOSC domain
RSC3_03695	COG2258	MOSC domain
RSC3_03696	COG0583	DNA-binding transcription factor activity
RSC3_03698	COG2721	sulfolactate sulfo-lyase activity
RSC3_03699	COG0246	Mannitol dehydrogenase
RSC3_03700	COG1609	Transcriptional regulator
RSC3_03701	COG2211	Major facilitator Superfamily
RSC3_03702	COG1904	glucuronate isomerase
RSC3_03703	COG2205	protein histidine kinase activity
RSC3_03704	COG0745	RESPONSE REGULATOR receiver
RSC3_03705	COG1120	ATPase activity
RSC3_03706	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_03707	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_03708	COG0531	amino acid
RSC3_03711	COG1988	membrane-bound metal-dependent
RSC3_03712	COG1368	sulfuric ester hydrolase activity
RSC3_03713	COG2814	Major facilitator Superfamily
RSC3_03715	COG0656	L-ascorbic acid biosynthetic process
RSC3_03716	COG1940	carbohydrate kinase activity
RSC3_03718	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RSC3_03720	COG0596	Alpha beta hydrolase
RSC3_03721	COG3973	AAA domain
RSC3_03722	COG2860	membrane
RSC3_03723	COG0456	acetyltransferase
RSC3_03723	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RSC3_03725	COG0456	acetyltransferase
RSC3_03726	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RSC3_03727	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RSC3_03728	COG2217	Heavy metal translocating P-type atpase
RSC3_03729	COG1653	transport
RSC3_03730	COG1175	transmembrane transport
RSC3_03731	COG0395	ABC-type sugar transport system, permease component
RSC3_03732	COG1501	Belongs to the glycosyl hydrolase 31 family
RSC3_03733	COG1501	Belongs to the glycosyl hydrolase 31 family
RSC3_03734	COG1472	Belongs to the glycosyl hydrolase 3 family
RSC3_03736	COG1121	(ABC) transporter
RSC3_03737	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RSC3_03738	COG0803	Belongs to the bacterial solute-binding protein 9 family
RSC3_03741	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSC3_03741	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC3_03741	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSC3_03742	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC3_03745	COG2217	Heavy metal translocating P-type atpase
RSC3_03746	COG2608	mercury ion transmembrane transporter activity
RSC3_03747	COG1937	Protein conserved in bacteria
RSC3_03748	COG0693	protein deglycase activity
RSC3_03749	COG1349	DNA-binding transcription factor activity
RSC3_03750	COG1070	Carbohydrate kinase
RSC3_03751	COG4952	isomerase
RSC3_03753	COG3347	Dehydrogenase
RSC3_03753	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_03754	COG2814	Major facilitator Superfamily
RSC3_03755	COG2814	Major facilitator Superfamily
RSC3_03756	COG2814	Major facilitator Superfamily
RSC3_03758	COG2124	cytochrome p450
RSC3_03760	COG1846	Transcriptional regulator
RSC3_03762	COG0673	inositol 2-dehydrogenase activity
RSC3_03763	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RSC3_03764	COG1054	Belongs to the UPF0176 family
RSC3_03766	COG1191	sigma factor activity
RSC3_03768	COG2140	Oxalate decarboxylase
RSC3_03772	COG5520	Belongs to the glycosyl hydrolase 30 family
RSC3_03773	COG3507	Belongs to the glycosyl hydrolase 43 family
RSC3_03777	COG5444	nuclease activity
RSC3_03781	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RSC3_03782	COG0557	exoribonuclease II activity
RSC3_03783	COG1647	Serine aminopeptidase, S33
RSC3_03784	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RSC3_03785	COG2002	toxin-antitoxin pair type II binding
RSC3_03786	COG1476	TRANSCRIPTIONal
RSC3_03787	COG1396	sequence-specific DNA binding
RSC3_03788	COG1396	sequence-specific DNA binding
RSC3_03789	COG1174	glycine betaine transport
RSC3_03790	COG1732	Glycine betaine
RSC3_03791	COG1174	glycine betaine transport
RSC3_03792	COG1125	glycine betaine transport
RSC3_03792	COG0517	IMP dehydrogenase activity
RSC3_03793	COG1510	regulation of RNA biosynthetic process
RSC3_03794	COG2095	MarC family integral membrane protein
RSC3_03795	COG3064	Membrane
RSC3_03796	COG4640	response to antibiotic
RSC3_03797	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC3_03802	COG0693	protein deglycase activity
RSC3_03803	COG0148	phosphopyruvate hydratase activity
RSC3_03804	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
RSC3_03805	COG0149	triose-phosphate isomerase activity
RSC3_03806	COG0126	phosphoglycerate kinase activity
RSC3_03807	COG0126	phosphoglycerate kinase activity
RSC3_03808	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RSC3_03809	COG2390	Transcriptional regulator
RSC3_03810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RSC3_03811	COG1113	amino acid transport
RSC3_03815	COG1556	Lactate utilization protein
RSC3_03816	COG1139	Iron-sulfur cluster binding protein
RSC3_03817	COG0247	lactate metabolic process
RSC3_03818	COG0247	lactate metabolic process
RSC3_03819	COG2186	Transcriptional regulator
RSC3_03820	COG1620	l-lactate permease
RSC3_03821	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RSC3_03823	COG5039	Polysaccharide pyruvyl transferase
RSC3_03824	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RSC3_03825	COG0110	maltose O-acetyltransferase activity
RSC3_03826	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RSC3_03827	COG2244	polysaccharide biosynthetic process
RSC3_03828	COG1216	Glycosyl transferase, family 2
RSC3_03829	COG5039	Polysaccharide pyruvyl transferase
RSC3_03830	COG1216	Glycosyl transferase, family 2
RSC3_03832	COG0438	transferase activity, transferring glycosyl groups
RSC3_03833	COG1215	transferase activity, transferring glycosyl groups
RSC3_03834	COG0438	transferase activity, transferring glycosyl groups
RSC3_03835	COG1086	Polysaccharide biosynthesis protein
RSC3_03837	COG0489	protein tyrosine kinase activity
RSC3_03838	COG3944	biosynthesis protein
RSC3_03839	COG1396	sequence-specific DNA binding
RSC3_03842	COG2249	NAD(P)H dehydrogenase (quinone) activity
RSC3_03843	COG2271	Major facilitator Superfamily
RSC3_03844	COG2271	Major facilitator Superfamily
RSC3_03846	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RSC3_03848	COG1454	alcohol dehydrogenase
RSC3_03849	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RSC3_03851	COG1733	regulation of RNA biosynthetic process
RSC3_03852	COG1902	pentaerythritol trinitrate reductase activity
RSC3_03853	COG1621	beta-fructofuranosidase activity
RSC3_03854	COG1621	beta-fructofuranosidase activity
RSC3_03856	COG0740	serine-type endopeptidase activity
RSC3_03857	COG1611	Belongs to the LOG family
RSC3_03858	COG1694	Mazg nucleotide pyrophosphohydrolase
RSC3_03859	COG1078	dGTPase activity
RSC3_03860	COG0659	secondary active sulfate transmembrane transporter activity
RSC3_03861	COG0288	reversible hydration of carbon dioxide
RSC3_03862	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RSC3_03863	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RSC3_03864	COG0640	Transcriptional regulator
RSC3_03865	COG0640	Transcriptional regulator
RSC3_03867	COG2732	(Barnase) inhibitor
RSC3_03868	COG2162	N-hydroxyarylamine O-acetyltransferase activity
RSC3_03869	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC3_03870	COG1481	regulation of sporulation
RSC3_03871	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RSC3_03872	COG1660	Displays ATPase and GTPase activities
RSC3_03873	COG1051	belongs to the nudix hydrolase family
RSC3_03874	COG0492	ferredoxin-NADP+ reductase activity
RSC3_03875	COG0457	Tetratricopeptide repeat
RSC3_03876	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RSC3_03877	COG0140	phosphoribosyl-ATP diphosphatase activity
RSC3_03877	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RSC3_03878	COG0107	imidazoleglycerol-phosphate synthase activity
RSC3_03879	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RSC3_03880	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RSC3_03881	COG0131	Imidazoleglycerol-phosphate dehydratase
RSC3_03882	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RSC3_03883	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RSC3_03884	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
RSC3_03885	COG4990	cell redox homeostasis
RSC3_03886	COG5297	Belongs to the glycosyl hydrolase family 6
RSC3_03887	COG0110	maltose O-acetyltransferase activity
RSC3_03888	COG0546	phosphoglycolate phosphatase activity
RSC3_03889	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
RSC3_03890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RSC3_03891	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
RSC3_03892	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
RSC3_03893	COG1846	Transcriptional regulator
RSC3_03894	COG2814	Major facilitator Superfamily
RSC3_03895	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RSC3_03896	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RSC3_03897	COG1950	PFAM Membrane protein of
RSC3_03898	COG1983	PspC domain protein
RSC3_03899	COG3595	metallopeptidase activity
RSC3_03903	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RSC3_03904	COG0556	nucleotide-excision repair
RSC3_03905	COG0556	nucleotide-excision repair
RSC3_03906	COG4897	Protein conserved in bacteria
RSC3_03908	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RSC3_03910	COG0793	Belongs to the peptidase S41A family
RSC3_03910	COG3409	Peptidoglycan-binding domain 1 protein
RSC3_03911	COG0473	3-isopropylmalate dehydrogenase activity
RSC3_03912	COG0791	NLP P60 protein
RSC3_03912	COG3883	PFAM NLP P60 protein
RSC3_03913	COG2177	Part of the ABC transporter FtsEX involved in
RSC3_03914	COG2884	Cell division ATP-binding protein ftsE
RSC3_03918	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC3_03919	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RSC3_03920	COG0653	protein targeting
RSC3_03921	COG0653	protein targeting
RSC3_03922	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RSC3_03925	COG1516	flagellar protein fliS
RSC3_03926	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
RSC3_03927	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
RSC3_03928	COG1334	flagellar protein FlaG
RSC3_03930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RSC3_03931	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
RSC3_03932	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
RSC3_03934	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RSC3_03935	COG1256	bacterial-type flagellum assembly
RSC3_03935	COG4786	Flagellar basal body rod
RSC3_03936	COG3418	PFAM FlgN family protein
RSC3_03937	COG2747	anti-sigma28 factor FlgM
RSC3_03939	COG1040	competence protein
RSC3_03941	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RSC3_03942	COG1307	EDD domain protein, DegV family
RSC3_03943	COG2197	response regulator
RSC3_03944	COG4585	Histidine kinase
RSC3_03945	COG1739	Uncharacterized protein family UPF0029
RSC3_03946	COG1739	Uncharacterized protein family UPF0029
RSC3_03947	COG1316	TRANSCRIPTIONal
RSC3_03949	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RSC3_03950	COG0438	transferase activity, transferring glycosyl groups
RSC3_03951	COG1215	transferase activity, transferring glycosyl groups
RSC3_03952	COG3206	protein involved in exopolysaccharide biosynthesis
RSC3_03953	COG3307	-O-antigen
RSC3_03954	COG3307	-O-antigen
RSC3_03955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RSC3_03956	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RSC3_03957	COG0297	glycogen (starch) synthase activity
RSC3_03957	COG0438	transferase activity, transferring glycosyl groups
RSC3_03958	COG2244	polysaccharide biosynthetic process
RSC3_03960	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSC3_03960	COG2247	cell wall binding repeat
RSC3_03961	COG2385	sporulation resulting in formation of a cellular spore
RSC3_03961	COG2247	cell wall binding repeat
RSC3_03963	COG1316	TRANSCRIPTIONal
RSC3_03964	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RSC3_03965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RSC3_03966	COG1215	transferase activity, transferring glycosyl groups
RSC3_03966	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RSC3_03967	COG0463	Glycosyl transferase, family 2
RSC3_03970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RSC3_03971	COG1134	teichoic acid transport
RSC3_03972	COG1682	transport, permease protein
RSC3_03974	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RSC3_03975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RSC3_03976	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RSC3_03977	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RSC3_03978	COG4193	domain, Protein
RSC3_03979	COG4193	domain, Protein
RSC3_03980	COG1482	cell wall glycoprotein biosynthetic process
RSC3_03981	COG1482	cell wall glycoprotein biosynthetic process
RSC3_03987	COG0800	Aldolase
RSC3_03988	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RSC3_03989	COG1609	Transcriptional regulator
RSC3_03990	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
RSC3_03991	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_03992	COG1063	alcohol dehydrogenase
RSC3_03994	COG2814	Major facilitator Superfamily
RSC3_03995	COG1316	TRANSCRIPTIONal
RSC3_03996	COG0561	phosphatase activity
RSC3_03997	COG0791	NLP P60 protein
RSC3_03999	COG2843	Capsule synthesis protein
RSC3_04001	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RSC3_04002	COG1609	Transcriptional regulator
RSC3_04003	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RSC3_04004	COG1869	D-ribose catabolic process
RSC3_04005	COG1129	ABC transporter
RSC3_04006	COG1172	Belongs to the binding-protein-dependent transport system permease family
RSC3_04007	COG1879	ABC-type sugar transport system periplasmic component
RSC3_04008	COG0583	DNA-binding transcription factor activity
RSC3_04009	COG2226	methyltransferase
RSC3_04010	COG3527	Alpha-acetolactate decarboxylase
RSC3_04011	COG0028	Belongs to the TPP enzyme family
RSC3_04012	COG0583	DNA-binding transcription factor activity
RSC3_04013	COG0405	Gamma-glutamyltransferase
RSC3_04014	COG0405	Gamma-glutamyltransferase
RSC3_04015	COG1522	sequence-specific DNA binding
RSC3_04016	COG2059	Chromate
RSC3_04017	COG2059	Chromate
RSC3_04018	COG4464	protein tyrosine phosphatase activity
RSC3_04019	COG3944	biosynthesis protein
RSC3_04021	COG4715	Zinc finger, swim domain protein
RSC3_04022	COG4715	Zinc finger, swim domain protein
RSC3_04023	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RSC3_04024	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RSC3_04025	COG3878	Protein conserved in bacteria
RSC3_04027	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RSC3_04030	COG0561	phosphatase activity
RSC3_04031	COG1349	DNA-binding transcription factor activity
RSC3_04033	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_04035	COG3732	PTS system glucitol sorbitol-specific
RSC3_04039	COG0629	single-stranded DNA binding
RSC3_04042	COG1970	mechanosensitive ion channel activity
RSC3_04043	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RSC3_04044	COG4786	Flagellar basal body rod
RSC3_04045	COG4786	Flagellar basal body rod
RSC3_04046	COG1077	Cell shape determining protein MreB Mrl
RSC3_04047	COG1609	Transcriptional regulator
RSC3_04048	COG1846	Transcriptional regulator
RSC3_04049	COG2814	Major facilitator Superfamily
RSC3_04050	COG0671	phosphoesterase, PA-phosphatase related
RSC3_04051	COG1227	inorganic diphosphatase activity
RSC3_04052	COG3546	catalase activity
RSC3_04053	COG3361	conserved protein (COG2071)
RSC3_04056	COG0517	IMP dehydrogenase activity
RSC3_04057	COG0598	Magnesium transport protein CorA
RSC3_04058	COG1253	flavin adenine dinucleotide binding
RSC3_04059	COG0004	ammonium transporteR
RSC3_04060	COG0004	ammonium transporteR
RSC3_04061	COG0347	Belongs to the P(II) protein family
RSC3_04062	COG0740	serine-type endopeptidase activity
RSC3_04064	COG0739	heme binding
RSC3_04065	COG1247	-acetyltransferase
RSC3_04067	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RSC3_04068	COG0477	Major facilitator Superfamily
RSC3_04069	COG3251	PFAM MbtH domain protein
RSC3_04070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_04071	COG1535	isochorismatase
RSC3_04071	COG3433	isochorismatase activity
RSC3_04072	COG1021	2,3-dihydroxybenzoate-AMP ligase
RSC3_04073	COG1169	isochorismate synthase
RSC3_04074	COG1028	Short-chain dehydrogenase reductase Sdr
RSC3_04075	COG2819	hydrolase of the alpha beta superfamily
RSC3_04076	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_04077	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_04078	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC3_04079	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC3_04079	COG2207	Transcriptional regulator
RSC3_04081	COG2910	NAD(P)H-binding
RSC3_04082	COG1959	2 iron, 2 sulfur cluster binding
RSC3_04084	COG1994	Peptidase M50
RSC3_04085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RSC3_04086	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RSC3_04090	COG3383	formate dehydrogenase (NAD+) activity
RSC3_04091	COG2304	oxidoreductase activity
RSC3_04092	COG2304	oxidoreductase activity
RSC3_04093	COG2385	sporulation resulting in formation of a cellular spore
RSC3_04094	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RSC3_04096	COG4836	Membrane
RSC3_04097	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RSC3_04098	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RSC3_04099	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RSC3_04100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RSC3_04101	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RSC3_04102	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RSC3_04104	COG0356	it plays a direct role in the translocation of protons across the membrane
RSC3_04106	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RSC3_04107	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RSC3_04108	COG4475	Protein of unknown function (DUF436)
RSC3_04109	COG4475	Protein of unknown function (DUF436)
RSC3_04110	COG0698	ribose 5-phosphate isomerase
RSC3_04111	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RSC3_04112	COG1971	Probably functions as a manganese efflux pump
RSC3_04113	COG0009	L-threonylcarbamoyladenylate synthase
RSC3_04114	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RSC3_04116	COG0738	Major facilitator superfamily
RSC3_04117	COG0673	inositol 2-dehydrogenase activity
RSC3_04118	COG0561	phosphatase activity
RSC3_04119	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RSC3_04120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RSC3_04121	COG1609	Transcriptional regulator
RSC3_04122	COG2890	protein-(glutamine-N5) methyltransferase activity
RSC3_04123	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RSC3_04124	COG0346	lactoylglutathione lyase activity
RSC3_04125	COG0789	Transcriptional regulator
RSC3_04126	COG0789	Transcriptional regulator
RSC3_04127	COG0679	Auxin Efflux Carrier
RSC3_04128	COG0281	malic enzyme
RSC3_04129	COG1435	thymidine kinase activity
RSC3_04130	COG0254	rRNA binding
RSC3_04131	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RSC3_04132	COG1494	fructose-1,6-bisphosphatase
RSC3_04133	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RSC3_04134	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RSC3_04135	COG0191	fructose-bisphosphate aldolase activity
RSC3_04136	COG2204	response regulator
RSC3_04137	COG4821	SIS domain
RSC3_04138	COG0504	CTP synthase activity
RSC3_04139	COG3343	RNA polymerase activity
RSC3_04140	COG1960	acyl-CoA dehydrogenase activity
RSC3_04141	COG1960	acyl-CoA dehydrogenase activity
RSC3_04142	COG1250	3-hydroxyacyl-CoA dehydrogenase
RSC3_04143	COG0183	Belongs to the thiolase family
RSC3_04144	COG0247	lactate metabolic process
RSC3_04144	COG2181	nitrate reductase activity
RSC3_04145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RSC3_04147	COG0018	arginyl-trna synthetase
RSC3_04148	COG4506	Protein conserved in bacteria
RSC3_04149	COG0010	Belongs to the arginase family
RSC3_04150	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
RSC3_04151	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RSC3_04153	COG1994	Peptidase M50
RSC3_04154	COG1942	4-Oxalocrotonate Tautomerase
RSC3_04156	COG3465	dGTPase activity
RSC3_04157	COG1078	dGTPase activity
RSC3_04158	COG4844	belongs to the
RSC3_04163	COG2814	Major facilitator Superfamily
RSC3_04168	COG1414	Transcriptional regulator
RSC3_04170	COG0280	phosphate acetyltransferase
RSC3_04171	COG3253	May function as heme-dependent peroxidase
RSC3_04173	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RSC3_04178	COG1131	(ABC) transporter
RSC3_04181	COG2363	Small membrane protein
RSC3_04182	COG2233	PERMEase
RSC3_04184	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_04185	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_04186	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RSC3_04187	COG1216	Glycosyl transferase, family 2
RSC3_04188	COG0351	phosphomethylpyrimidine kinase
RSC3_04190	COG1621	beta-fructofuranosidase activity
RSC3_04191	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC3_04191	COG1263	PTS System
RSC3_04192	COG3711	transcriptional antiterminator
RSC3_04194	COG1404	Belongs to the peptidase S8 family
RSC3_04196	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RSC3_04198	COG0778	Nitroreductase
RSC3_04199	COG1473	amidohydrolase
RSC3_04200	COG0772	Belongs to the SEDS family
RSC3_04201	COG0772	Belongs to the SEDS family
RSC3_04202	COG3314	Sporulation integral membrane protein YlbJ
RSC3_04207	COG0456	acetyltransferase
RSC3_04210	COG1132	(ABC) transporter
RSC3_04218	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RSC3_04220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RSC3_04221	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RSC3_04222	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RSC3_04223	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RSC3_04225	COG0655	NAD(P)H dehydrogenase (quinone) activity
RSC3_04226	COG3162	membrane
RSC3_04227	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC3_04228	COG1070	Carbohydrate kinase
RSC3_04229	COG2115	Belongs to the xylose isomerase family
RSC3_04230	COG2115	Belongs to the xylose isomerase family
RSC3_04231	COG1940	carbohydrate kinase activity
RSC3_04232	COG0352	thiamine-phosphate diphosphorylase activity
RSC3_04233	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
RSC3_04234	COG0583	DNA-binding transcription factor activity
RSC3_04237	COG1380	Effector of murein hydrolase LrgA
RSC3_04238	COG1346	cytolysis
RSC3_04240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSC3_04241	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RSC3_04242	COG0346	lactoylglutathione lyase activity
RSC3_04243	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RSC3_04244	COG1442	glycosyl transferase family 8
RSC3_04248	COG4585	Histidine kinase
RSC3_04249	COG2197	response regulator
RSC3_04250	COG2409	Drug exporters of the RND superfamily
RSC3_04251	COG5522	Integral membrane protein (intg_mem_TP0381)
RSC3_04252	COG2271	Major facilitator Superfamily
RSC3_04253	COG4948	Mandelate Racemase Muconate Lactonizing
RSC3_04254	COG0800	Aldolase
RSC3_04255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RSC3_04257	COG2234	aminopeptidase activity
RSC3_04258	COG0477	Major facilitator Superfamily
RSC3_04259	COG0477	Major facilitator Superfamily
RSC3_04262	COG2357	RelA SpoT domain protein
RSC3_04264	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RSC3_04265	COG1696	Membrane protein involved in D-alanine export
RSC3_04266	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RSC3_04267	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RSC3_04268	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RSC3_04269	COG2814	Major facilitator Superfamily
RSC3_04270	COG1486	melibiose metabolic process
RSC3_04271	COG1447	Phosphotransferase system cellobiose-specific component IIA
RSC3_04272	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC3_04273	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC3_04274	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSC3_04274	COG3711	transcriptional antiterminator
RSC3_04276	COG2094	Belongs to the DNA glycosylase MPG family
RSC3_04278	COG0372	Belongs to the citrate synthase family
RSC3_04279	COG2079	MmgE PrpD family protein
RSC3_04280	COG2079	MmgE PrpD family protein
RSC3_04281	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RSC3_04284	COG1132	(ABC) transporter
RSC3_04285	COG1132	(ABC) transporter
RSC3_04286	COG1132	(ABC) transporter
RSC3_04287	COG2755	lipolytic protein G-D-S-L family
RSC3_04290	COG2814	Major facilitator Superfamily
RSC3_04292	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RSC3_04293	COG1131	(ABC) transporter
RSC3_04297	COG1595	DNA-templated transcription, initiation
RSC3_04298	COG2814	Major facilitator Superfamily
RSC3_04299	COG2814	Major facilitator Superfamily
RSC3_04302	COG0753	catalase activity
RSC3_04303	COG0753	catalase activity
RSC3_04304	COG0735	belongs to the Fur family
RSC3_04305	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RSC3_04307	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RSC3_04308	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RSC3_04309	COG4988	ABC transporter
RSC3_04310	COG1294	oxidase, subunit
RSC3_04311	COG1271	oxidase subunit
RSC3_04312	COG2116	formate transmembrane transporter activity
RSC3_04314	COG0281	malic enzyme
RSC3_04315	COG1757	Na H antiporter
RSC3_04316	COG1027	Aspartate ammonia-lyase
RSC3_04317	COG0252	asparaginase activity
RSC3_04318	COG1396	sequence-specific DNA binding
RSC3_04319	COG2706	6-phosphogluconolactonase activity
RSC3_04320	COG0745	RESPONSE REGULATOR receiver
RSC3_04321	COG2205	protein histidine kinase activity
RSC3_04322	COG1136	(ABC) transporter
RSC3_04323	COG0577	efflux transmembrane transporter activity
RSC3_04324	COG5294	Protein conserved in bacteria
RSC3_04327	COG0726	polysaccharide deacetylase
RSC3_04328	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RSC3_04330	COG3493	citrate carrier protein
RSC3_04331	COG0584	glycerophosphoryl diester phosphodiesterase
RSC3_04334	COG1368	sulfuric ester hydrolase activity
RSC3_04336	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RSC3_04338	COG2235	arginine
RSC3_04339	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RSC3_04341	COG0549	Belongs to the carbamate kinase family
RSC3_04343	COG2723	6-phospho-beta-galactosidase activity
RSC3_04344	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RSC3_04346	COG1595	DNA-templated transcription, initiation
RSC3_04348	COG2195	Cleaves the N-terminal amino acid of tripeptides
RSC3_04351	COG2223	nitrite transmembrane transporter activity
RSC3_04352	COG0395	ABC-type sugar transport system, permease component
RSC3_04353	COG1175	transmembrane transport
RSC3_04355	COG1609	Transcriptional regulator
RSC3_04358	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RSC3_04359	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RSC3_04360	COG0463	Glycosyl transferase, family 2
RSC3_04361	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RSC3_04366	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RSC3_04367	COG0753	catalase activity
RSC3_04367	COG0693	protein deglycase activity
RSC3_04369	COG2723	6-phospho-beta-galactosidase activity
RSC3_04370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC3_04370	COG1263	PTS System
RSC3_04370	COG2190	(PTS) system
RSC3_04371	COG1263	PTS System
RSC3_04371	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC3_04371	COG2190	(PTS) system
RSC3_04372	COG3711	transcriptional antiterminator
RSC3_04373	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RSC3_04374	COG1122	ATPase activity
RSC3_04375	COG4721	ABC-type cobalt transport system, permease component
RSC3_04376	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RSC3_04378	COG2224	Isocitrate lyase
RSC3_04379	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RSC3_04381	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RSC3_04391	COG0577	efflux transmembrane transporter activity
RSC3_04392	COG1136	(ABC) transporter
RSC3_04393	COG1136	(ABC) transporter
RSC3_04394	COG2205	protein histidine kinase activity
RSC3_04395	COG0745	RESPONSE REGULATOR receiver
RSC3_04396	COG2723	6-phospho-beta-galactosidase activity
RSC3_04397	COG2190	(PTS) system
RSC3_04397	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC3_04397	COG1263	PTS System
RSC3_04399	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
RSC3_04400	COG3507	Belongs to the glycosyl hydrolase 43 family
RSC3_04401	COG0513	Belongs to the DEAD box helicase family
RSC3_04404	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
RSC3_04405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RSC3_04406	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RSC3_04407	COG2390	Transcriptional regulator
RSC3_04409	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
RSC3_04410	COG3706	GGDEF domain
RSC3_04411	COG5298	Protein conserved in bacteria
RSC3_04412	COG1215	transferase activity, transferring glycosyl groups
RSC3_04414	COG3977	Valine--pyruvate aminotransferase
RSC3_04421	COG0191	fructose-bisphosphate aldolase activity
RSC3_04422	COG1082	Xylose isomerase domain protein TIM barrel
RSC3_04423	COG1082	Xylose isomerase domain protein TIM barrel
RSC3_04424	COG0673	inositol 2-dehydrogenase activity
RSC3_04425	COG2814	Major facilitator Superfamily
RSC3_04426	COG1082	Xylose isomerase domain protein TIM barrel
RSC3_04427	COG3962	Belongs to the TPP enzyme family
RSC3_04428	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RSC3_04429	COG3718	enzyme involved in inositol metabolism
RSC3_04430	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_04431	COG1349	DNA-binding transcription factor activity
RSC3_04432	COG0667	Aldo Keto reductase
RSC3_04433	COG0584	glycerophosphoryl diester phosphodiesterase
RSC3_04434	COG2271	Major facilitator Superfamily
RSC3_04435	COG0326	Molecular chaperone. Has ATPase activity
RSC3_04436	COG0488	(ABC) transporter
RSC3_04437	COG0561	phosphatase activity
RSC3_04441	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC3_04448	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
RSC3_04449	COG0577	efflux transmembrane transporter activity
RSC3_04450	COG1136	(ABC) transporter
RSC3_04451	COG1136	(ABC) transporter
RSC3_04452	COG2205	protein histidine kinase activity
RSC3_04453	COG0745	RESPONSE REGULATOR receiver
RSC3_04455	COG5278	phosphoserine phosphatase activity
RSC3_04455	COG0840	transmembrane signaling receptor activity
RSC3_04456	COG1115	amino acid carrier protein
RSC3_04457	COG0686	Belongs to the AlaDH PNT family
RSC3_04458	COG3867	Arabinogalactan endo-beta-1,4-galactanase
RSC3_04459	COG1874	Beta-galactosidase
RSC3_04460	COG3833	ABC-type maltose transport systems, permease component
RSC3_04461	COG1175	transmembrane transport
RSC3_04462	COG2182	Extracellular solute-binding protein
RSC3_04463	COG1609	Transcriptional regulator
RSC3_04464	COG1609	Transcriptional regulator
RSC3_04465	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
RSC3_04466	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
RSC3_04467	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RSC3_04468	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
RSC3_04469	COG1940	carbohydrate kinase activity
RSC3_04471	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RSC3_04478	COG1012	belongs to the aldehyde dehydrogenase family
RSC3_04478	COG1454	alcohol dehydrogenase
RSC3_04479	COG0450	alkyl hydroperoxide reductase
RSC3_04480	COG3634	alkyl hydroperoxide reductase activity
RSC3_04482	COG1113	amino acid transport
RSC3_04483	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
RSC3_04484	COG3634	alkyl hydroperoxide reductase activity
RSC3_04485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC3_04486	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSC3_04487	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_04488	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSC3_04491	COG1131	(ABC) transporter
RSC3_04492	COG0842	Transport permease protein
RSC3_04493	COG4585	Histidine kinase
RSC3_04494	COG2197	response regulator
RSC3_04498	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RSC3_04501	COG0456	acetyltransferase
RSC3_04504	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RSC3_04505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RSC3_04506	COG4853	Protein conserved in bacteria
RSC3_04507	COG4863	YycH protein
RSC3_04508	COG5002	protein histidine kinase activity
RSC3_04509	COG0745	RESPONSE REGULATOR receiver
RSC3_04510	COG1051	belongs to the nudix hydrolase family
RSC3_04511	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RSC3_04513	COG0305	Participates in initiation and elongation during chromosome replication
RSC3_04516	COG3093	addiction module antidote protein HigA
RSC3_04517	COG2807	transmembrane transport
RSC3_04518	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RSC3_04519	COG0363	glucosamine-6-phosphate deaminase activity
RSC3_04520	COG2188	Transcriptional regulator
RSC3_04521	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
RSC3_04522	COG1263	PTS System
RSC3_04522	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RSC3_04523	COG0359	binds to the 23S rRNA
RSC3_04524	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RSC3_04525	COG4241	membrane
RSC3_04528	COG5577	PFAM Coat F domain
RSC3_04529	COG0589	response to stress
RSC3_04530	COG0659	secondary active sulfate transmembrane transporter activity
RSC3_04531	COG2271	Major facilitator Superfamily
RSC3_04532	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RSC3_04533	COG0629	single-stranded DNA binding
RSC3_04534	COG0360	Binds together with S18 to 16S ribosomal RNA
RSC3_04535	COG0012	GTP binding
RSC3_04536	COG4481	Protein conserved in bacteria
RSC3_04537	COG3949	Membrane
RSC3_04538	COG3949	Membrane
RSC3_04540	COG1475	DNA binding
RSC3_04541	COG1192	Involved in chromosome partitioning
RSC3_04542	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RSC3_04543	COG1595	DNA-templated transcription, initiation
RSC3_04544	COG1475	DNA binding
RSC3_04545	COG0357	Ribosomal RNA small subunit methyltransferase G
RSC3_04546	COG0445	tRNA wobble uridine modification
RSC3_04547	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RSC3_04548	COG1847	R3H domain protein
RSC3_04549	COG0706	membrane insertase activity
RSC3_04550	COG0594	ribonuclease P activity
RSC3_04552	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RSC3_04553	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RSC3_04554	COG0592	DNA-directed DNA polymerase activity
RSC3_04556	COG2501	S4 domain
RSC3_04557	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RSC3_04558	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RSC3_04559	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RSC3_04561	COG0187	DNA topoisomerase II activity
RSC3_04562	COG0187	DNA topoisomerase II activity
RSC3_04563	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RSC3_04568	COG0516	GMP reductase activity
RSC3_04568	COG0517	IMP dehydrogenase activity
RSC3_04569	COG1686	Belongs to the peptidase S11 family
RSC3_04570	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
RSC3_04571	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
RSC3_04572	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RSC3_04573	COG1929	Belongs to the glycerate kinase type-1 family
RSC3_04574	COG2610	gluconate transmembrane transporter activity
RSC3_04575	COG3835	regulator
RSC3_04577	COG1428	Deoxynucleoside kinase
RSC3_04578	COG1428	Deoxynucleoside kinase
RSC3_04579	COG1388	LysM domain
RSC3_04579	COG3858	chitin binding
RSC3_04580	COG1388	LysM domain
RSC3_04580	COG3858	chitin binding
RSC3_04581	COG1335	isochorismatase
RSC3_04582	COG0590	tRNA wobble adenosine to inosine editing
RSC3_04583	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RSC3_04584	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RSC3_04585	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RSC3_04586	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RSC3_04593	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
RSC3_04594	COG3853	Toxic anion resistance protein (TelA)
RSC3_04595	COG1982	Orn Lys Arg decarboxylase major
RSC3_04596	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RSC3_04597	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RSC3_04598	COG3870	Protein conserved in bacteria
RSC3_04599	COG1728	Protein conserved in bacteria
RSC3_04600	COG0470	DNA polymerase III
RSC3_04601	COG1774	PSP1 C-terminal conserved region
RSC3_04602	COG4467	Involved in initiation control of chromosome replication
RSC3_04603	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RSC3_04604	COG2827	Endonuclease containing a URI domain
RSC3_04605	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RSC3_04606	COG2002	toxin-antitoxin pair type II binding
RSC3_04607	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RSC3_04607	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RSC3_04608	COG0084	hydrolase, TatD family'
RSC3_04609	COG3583	domain protein
RSC3_04609	COG3584	3D domain protein
RSC3_04610	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RSC3_04611	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RSC3_04612	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RSC3_04614	COG4466	Protein conserved in bacteria
RSC3_04616	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RSC3_04617	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RSC3_04618	COG0251	oxidation-reduction process
RSC3_04619	COG2088	sporulation resulting in formation of a cellular spore
RSC3_04620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RSC3_04621	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RSC3_04622	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RSC3_04623	COG0193	aminoacyl-tRNA hydrolase activity
RSC3_04625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RSC3_04626	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RSC3_04627	COG2002	toxin-antitoxin pair type II binding
RSC3_04628	COG2002	toxin-antitoxin pair type II binding
RSC3_04629	COG2244	polysaccharide biosynthetic process
RSC3_04630	COG3956	TIGRFAM MazG family protein
RSC3_04631	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RSC3_04633	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
RSC3_04634	COG1098	S1 RNA binding domain
RSC3_04636	COG2208	phosphoserine phosphatase activity
RSC3_04637	COG2304	oxidoreductase activity
RSC3_04638	COG0515	serine threonine protein kinase
RSC3_04639	COG0037	tRNA processing
RSC3_04640	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RSC3_04641	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RSC3_04642	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RSC3_04643	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
RSC3_04644	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RSC3_04645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RSC3_04646	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RSC3_04647	COG0512	Glutamine amidotransferase of anthranilate synthase
RSC3_04648	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RSC3_04649	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RSC3_04650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RSC3_04651	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RSC3_04652	COG1396	sequence-specific DNA binding
RSC3_04653	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RSC3_04654	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RSC3_04655	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RSC3_04662	COG4463	regulation of RNA biosynthetic process
RSC3_04663	COG3880	PFAM UvrB UvrC protein
RSC3_04664	COG3869	Catalyzes the specific phosphorylation of arginine residues in
RSC3_04665	COG0542	response to heat
RSC3_04666	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RSC3_04667	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
RSC3_04668	COG4956	integral membrane protein (PIN domain superfamily)
RSC3_04669	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RSC3_04670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RSC3_04671	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RSC3_04672	COG1045	serine acetyltransferase
RSC3_04673	COG0215	cysteine-tRNA ligase activity
RSC3_04674	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)