locus-tag	class	description
KY998_00010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KY998_00015	COG3881	PFAM PRC-barrel domain
KY998_00035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KY998_00040	COG4472	Bacterial protein of unknown function (DUF965)
KY998_00045	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KY998_00050	COG3906	Belongs to the UPF0473 family
KY998_00055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KY998_00060	COG4122	O-methyltransferase activity
KY998_00070	COG0826	peptidase U32
KY998_00075	COG0572	uridine kinase
KY998_00080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KY998_00085	COG0768	penicillin binding
KY998_00100	COG2226	methyltransferase
KY998_00105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KY998_00115	COG0626	cystathionine gamma-synthase activity
KY998_00140	COG2226	methyltransferase
KY998_00145	COG1404	Belongs to the peptidase S8 family
KY998_00155	COG1309	transcriptional regulator
KY998_00160	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KY998_00160	COG2124	cytochrome p450
KY998_00170	COG2814	Major facilitator Superfamily
KY998_00175	COG0583	DNA-binding transcription factor activity
KY998_00180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KY998_00190	COG1587	Uroporphyrinogen-III synthase
KY998_00200	COG1733	regulation of RNA biosynthetic process
KY998_00205	COG2814	Major facilitator Superfamily
KY998_00210	COG0656	L-ascorbic acid biosynthetic process
KY998_00220	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KY998_00235	COG2205	protein histidine kinase activity
KY998_00240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KY998_00245	COG2169	Transcriptional regulator
KY998_00265	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KY998_00265	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KY998_00270	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KY998_00275	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KY998_00280	COG3715	PTS system
KY998_00285	COG3716	PTS system mannose fructose sorbose family IID component
KY998_00290	COG1621	beta-fructofuranosidase activity
KY998_00310	COG3507	Belongs to the glycosyl hydrolase 43 family
KY998_00315	COG2124	cytochrome p450
KY998_00330	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KY998_00340	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_00360	COG4608	Belongs to the ABC transporter superfamily
KY998_00380	COG0747	negative chemotaxis
KY998_00385	COG0492	ferredoxin-NADP+ reductase activity
KY998_00390	COG2197	response regulator
KY998_00395	COG4585	Histidine kinase
KY998_00400	COG3239	Fatty acid desaturase
KY998_00405	COG1733	regulation of RNA biosynthetic process
KY998_00410	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KY998_00415	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KY998_00420	COG1942	4-Oxalocrotonate Tautomerase
KY998_00455	COG2210	Belongs to the sulfur carrier protein TusA family
KY998_00460	COG1054	Belongs to the UPF0176 family
KY998_00465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KY998_00465	COG0425	Belongs to the sulfur carrier protein TusA family
KY998_00470	COG2210	Belongs to the sulfur carrier protein TusA family
KY998_00485	COG0425	Belongs to the sulfur carrier protein TusA family
KY998_00490	COG0730	response to heat
KY998_00495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KY998_00530	COG2223	nitrite transmembrane transporter activity
KY998_00535	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KY998_00540	COG1140	nitrate reductase beta subunit
KY998_00545	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KY998_00560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KY998_00565	COG1447	Phosphotransferase system cellobiose-specific component IIA
KY998_00570	COG2723	6-phospho-beta-galactosidase activity
KY998_00595	COG1247	-acetyltransferase
KY998_00610	COG0251	oxidation-reduction process
KY998_00615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KY998_00625	COG0251	oxidation-reduction process
KY998_00635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KY998_00650	COG2427	Protein of unknown function (DUF1641)
KY998_00655	COG3383	formate dehydrogenase (NAD+) activity
KY998_00660	COG5609	conserved protein (DUF2294)
KY998_00670	COG2755	lipolytic protein G-D-S-L family
KY998_00685	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KY998_00690	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KY998_00695	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KY998_00700	COG1534	Rna-binding protein
KY998_00705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KY998_00710	COG1713	HD superfamily hydrolase involved in NAD metabolism
KY998_00715	COG0799	negative regulation of ribosome biogenesis
KY998_00720	COG2226	methyltransferase
KY998_00725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KY998_00730	COG1555	photosystem II stabilization
KY998_00730	COG1596	polysaccharide export
KY998_00735	COG2131	deaminase
KY998_00740	COG0658	competence protein
KY998_00740	COG2333	competence protein COMEC
KY998_00750	COG1466	dna polymerase III delta subunit
KY998_00760	COG0268	Binds directly to 16S ribosomal RNA
KY998_00765	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KY998_00770	COG0860	N-Acetylmuramoyl-L-alanine amidase
KY998_00780	COG0481	GTPase activity
KY998_00785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KY998_00790	COG1420	regulation of RNA biosynthetic process
KY998_00795	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KY998_00800	COG0443	Heat shock 70 kDa protein
KY998_00805	COG0484	heat shock protein binding
KY998_00810	COG2264	protein methyltransferase activity
KY998_00815	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KY998_00820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KY998_00825	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KY998_00830	COG1283	sodium-dependent phosphate transmembrane transporter activity
KY998_00835	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KY998_00840	COG1610	YqeY-like protein
KY998_00845	COG1030	water channel activity
KY998_00850	COG4864	UPF0365 protein
KY998_00865	COG0561	phosphatase activity
KY998_00870	COG1702	phosphate starvation-inducible protein PhoH
KY998_00875	COG1480	7TM receptor with intracellular HD hydrolase
KY998_00880	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KY998_00885	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KY998_00890	COG0295	cytidine deaminase activity
KY998_00895	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KY998_00905	COG1381	Involved in DNA repair and RecF pathway recombination
KY998_00910	COG0752	glycyl-tRNA synthetase alpha subunit
KY998_00915	COG0751	glycine-tRNA ligase activity
KY998_00920	COG0517	IMP dehydrogenase activity
KY998_00925	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KY998_00930	COG1671	Belongs to the UPF0178 family
KY998_00935	COG0358	DNA primase activity
KY998_00945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KY998_00950	COG2010	Cytochrome c
KY998_00965	COG5444	nuclease activity
KY998_00990	COG2384	SAM-dependent methyltransferase
KY998_00995	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KY998_01000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KY998_01015	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KY998_01025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KY998_01030	COG1121	(ABC) transporter
KY998_01035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KY998_01040	COG0735	belongs to the Fur family
KY998_01045	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KY998_01050	COG4709	membrane
KY998_01055	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KY998_01060	COG1388	LysM domain
KY998_01065	COG5521	maltodextrose utilization protein MalA
KY998_01070	COG2839	Protein conserved in bacteria
KY998_01075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KY998_01080	COG0477	Major facilitator Superfamily
KY998_01085	COG0768	penicillin binding
KY998_01090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KY998_01095	COG0573	inorganic phosphate transmembrane transporter activity
KY998_01100	COG0581	inorganic phosphate transmembrane transporter activity
KY998_01110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KY998_01155	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KY998_01170	COG0438	transferase activity, transferring glycosyl groups
KY998_01175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KY998_01180	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KY998_01190	COG0457	Tetratricopeptide repeat
KY998_01190	COG0705	Rhomboid family
KY998_01200	COG4483	Protein conserved in bacteria
KY998_01205	COG1940	carbohydrate kinase activity
KY998_01210	COG1368	sulfuric ester hydrolase activity
KY998_01215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KY998_01220	COG2866	Carboxypeptidase
KY998_01230	COG0011	TIGRFAM Protein of
KY998_01240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KY998_01250	COG1393	Belongs to the ArsC family
KY998_01260	COG1366	Belongs to the anti-sigma-factor antagonist family
KY998_01265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KY998_01270	COG1459	type II secretion system
KY998_01275	COG4537	Required for transformation and DNA binding
KY998_01280	COG4970	Tfp pilus assembly protein FimT
KY998_01290	COG4940	Competence protein ComGF
KY998_01315	COG0681	Belongs to the peptidase S26 family
KY998_01340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KY998_01345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KY998_01350	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KY998_01355	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KY998_01365	COG4176	ABC-type proline glycine betaine transport system permease component
KY998_01370	COG2113	Glycine betaine
KY998_01375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KY998_01380	COG0095	Lipoate-protein ligase
KY998_01385	COG1321	iron dependent repressor
KY998_01390	COG1752	Esterase of the alpha-beta hydrolase superfamily
KY998_01400	COG3872	metal-dependent enzyme
KY998_01410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KY998_01415	COG0006	proline dipeptidase activity
KY998_01420	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KY998_01430	COG3854	ATPases associated with a variety of cellular activities
KY998_01470	COG0511	ligase activity, forming carbon-carbon bonds
KY998_01475	COG0439	Biotin carboxylase
KY998_01480	COG1302	Protein conserved in bacteria
KY998_01485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KY998_01490	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KY998_01495	COG1570	exodeoxyribonuclease VII activity
KY998_01500	COG1722	exodeoxyribonuclease VII activity
KY998_01505	COG0142	geranyltranstransferase activity
KY998_01510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KY998_01515	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KY998_01520	COG1438	arginine binding
KY998_01525	COG0497	DNA recombination
KY998_01530	COG0750	zinc metalloprotease
KY998_01535	COG0745	RESPONSE REGULATOR receiver
KY998_01555	COG0860	N-Acetylmuramoyl-L-alanine amidase
KY998_01560	COG0584	glycerophosphoryl diester phosphodiesterase
KY998_01570	COG3829	transcription factor binding
KY998_01570	COG3290	protein histidine kinase activity
KY998_01575	COG0280	phosphate acetyltransferase
KY998_01585	COG3426	butyrate kinase activity
KY998_01590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KY998_01595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KY998_01600	COG0022	dehydrogenase e1 component
KY998_01605	COG0508	dehydrogenase complex catalyzes the overall conversion of
KY998_01610	COG1597	lipid kinase activity
KY998_01625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KY998_01640	COG4129	membrane
KY998_01655	COG2195	Cleaves the N-terminal amino acid of tripeptides
KY998_01660	COG0706	membrane insertase activity
KY998_01670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KY998_01675	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KY998_01680	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_01685	COG1785	Belongs to the alkaline phosphatase family
KY998_01690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KY998_01700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KY998_01705	COG2723	6-phospho-beta-galactosidase activity
KY998_01710	COG2188	Transcriptional regulator
KY998_01715	COG2358	TRAP transporter, solute receptor (TAXI family
KY998_01740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KY998_01750	COG1902	pentaerythritol trinitrate reductase activity
KY998_01755	COG4187	Peptidase family M20/M25/M40
KY998_01760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KY998_01765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KY998_01770	COG0300	oxidoreductase activity
KY998_01775	COG4195	phage-related replication protein
KY998_01790	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KY998_01815	COG2205	protein histidine kinase activity
KY998_01840	COG1131	(ABC) transporter
KY998_01850	COG1072	(Pantothenic acid kinase))
KY998_01855	COG0346	lactoylglutathione lyase activity
KY998_01870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KY998_01885	COG0534	Mate efflux family protein
KY998_01895	COG0444	Belongs to the ABC transporter superfamily
KY998_01905	COG0601	transmembrane transport
KY998_01910	COG0747	negative chemotaxis
KY998_01920	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KY998_01930	COG2329	Antibiotic biosynthesis monooxygenase
KY998_01935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KY998_01935	COG0456	acetyltransferase
KY998_01945	COG4918	Iron-sulphur cluster biosynthesis
KY998_01955	COG1073	alpha beta
KY998_01965	COG0667	Aldo Keto reductase
KY998_01975	COG1309	transcriptional regulator
KY998_01985	COG0494	nUDIX hydrolase
KY998_01990	COG1379	DNA repair
KY998_01995	COG2153	protein acetylation
KY998_02005	COG1953	Uracil, thiamine, allantoin
KY998_02015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KY998_02020	COG1300	Membrane
KY998_02025	COG0735	belongs to the Fur family
KY998_02035	COG4974	Belongs to the 'phage' integrase family
KY998_02040	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KY998_02045	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KY998_02050	COG1686	Belongs to the peptidase S11 family
KY998_02110	COG0019	diaminopimelate decarboxylase activity
KY998_02115	COG4195	phage-related replication protein
KY998_02120	COG4086	secreted protein
KY998_02125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KY998_02150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KY998_02150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KY998_02155	COG0307	riboflavin synthase, alpha
KY998_02160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KY998_02160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KY998_02165	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KY998_02170	COG0456	acetyltransferase
KY998_02180	COG1547	Domain of unknown function (DUF309)
KY998_02190	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KY998_02195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KY998_02205	COG1686	Belongs to the peptidase S11 family
KY998_02215	COG0700	Nucleoside recognition
KY998_02225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KY998_02230	COG1333	cytochrome c biogenesis protein
KY998_02240	COG0745	RESPONSE REGULATOR receiver
KY998_02250	COG0745	RESPONSE REGULATOR receiver
KY998_02255	COG5002	protein histidine kinase activity
KY998_02270	COG1316	TRANSCRIPTIONal
KY998_02275	COG1595	DNA-templated transcription, initiation
KY998_02285	COG0739	heme binding
KY998_02290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KY998_02295	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KY998_02300	COG1141	Ferredoxin
KY998_02305	COG4955	Helix-turn-helix domain
KY998_02310	COG0514	ATP-dependent DNA helicase (RecQ)
KY998_02315	COG1266	CAAX protease self-immunity
KY998_02320	COG1388	LysM domain
KY998_02335	COG1408	metallophosphoesterase
KY998_02340	COG4862	establishment of competence for transformation
KY998_02345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KY998_02350	COG0492	ferredoxin-NADP+ reductase activity
KY998_02360	COG2339	peptidase activity
KY998_02365	COG3409	Peptidoglycan-binding domain 1 protein
KY998_02365	COG3773	Cell wall hydrolase
KY998_02370	COG2959	enzyme of heme biosynthesis
KY998_02380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KY998_02385	COG0539	negative regulation of cytoplasmic translation
KY998_02390	COG1304	FMN binding
KY998_02415	COG1160	GTP binding
KY998_02420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KY998_02435	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KY998_02440	COG0776	regulation of translation
KY998_02455	COG0142	geranyltranstransferase activity
KY998_02460	COG2226	methyltransferase
KY998_02465	COG0142	geranyltranstransferase activity
KY998_02470	COG0105	UTP biosynthetic process
KY998_02475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KY998_02480	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KY998_02485	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KY998_02490	COG4401	Chorismate mutase type I
KY998_02500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KY998_02505	COG0134	indole-3-glycerol-phosphate synthase activity
KY998_02510	COG0135	phosphoribosylanthranilate isomerase activity
KY998_02515	COG0133	tryptophan synthase activity
KY998_02520	COG0159	tryptophan synthase activity
KY998_02525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KY998_02530	COG0287	Prephenate dehydrogenase
KY998_02535	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KY998_02540	COG0457	Tetratricopeptide repeat
KY998_02545	COG5582	Belongs to the UPF0302 family
KY998_02555	COG0723	plastoquinol--plastocyanin reductase activity
KY998_02560	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KY998_02565	COG2010	Cytochrome c
KY998_02565	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KY998_02575	COG4347	Protein of unknown function (DUF1405)
KY998_02585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KY998_02590	COG1694	Mazg nucleotide pyrophosphohydrolase
KY998_02595	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KY998_02600	COG1803	Methylglyoxal synthase
KY998_02605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KY998_02610	COG0438	transferase activity, transferring glycosyl groups
KY998_02615	COG0617	tRNA 3'-terminal CCA addition
KY998_02625	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KY998_02630	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KY998_02635	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KY998_02640	COG1199	ATP-dependent helicase activity
KY998_02640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KY998_02650	COG5353	protein conserved in bacteria
KY998_02655	COG0436	Aminotransferase
KY998_02660	COG0017	Asparaginyl-tRNA synthetase
KY998_02665	COG3935	DnaD domain protein
KY998_02670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KY998_02680	COG4499	WXG100 protein secretion system (Wss), protein YukC
KY998_02680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KY998_02685	COG3331	DNA recombination
KY998_02720	COG0071	Belongs to the small heat shock protein (HSP20) family
KY998_02725	COG2190	(PTS) system
KY998_02730	COG1111	helicase
KY998_02730	COG1205	dead DEAH box helicase
KY998_02735	COG3359	exonuclease
KY998_02745	COG4474	Belongs to the UPF0398 family
KY998_02750	COG3599	regulation of cell shape
KY998_02760	COG0116	Belongs to the methyltransferase superfamily
KY998_02775	COG1199	ATP-dependent helicase activity
KY998_02780	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KY998_02785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KY998_02790	COG2233	PERMEase
KY998_02800	COG3424	synthase
KY998_02805	COG1755	Isoprenylcysteine carboxyl methyltransferase
KY998_02815	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KY998_02840	COG0328	RNA-DNA hybrid ribonuclease activity
KY998_02845	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KY998_02850	COG0328	RNA-DNA hybrid ribonuclease activity
KY998_02870	COG1278	Cold shock
KY998_02880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KY998_02885	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KY998_02890	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KY998_02895	COG0386	Belongs to the glutathione peroxidase family
KY998_02900	COG1418	mRNA catabolic process
KY998_02910	COG0129	dihydroxy-acid dehydratase activity
KY998_02920	COG2136	Putative SAM-dependent methyltransferase
KY998_02920	COG2521	methyltransferase
KY998_02930	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KY998_02935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KY998_02940	COG0204	Acyl-transferase
KY998_02945	COG1272	protein, Hemolysin III
KY998_02970	COG1999	signal sequence binding
KY998_02975	COG2755	lipolytic protein G-D-S-L family
KY998_02980	COG4698	Protein conserved in bacteria
KY998_02995	COG0534	Mate efflux family protein
KY998_03000	COG3706	GGDEF domain
KY998_03010	COG1846	Transcriptional regulator
KY998_03015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KY998_03020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KY998_03025	COG0456	acetyltransferase
KY998_03040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KY998_03045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KY998_03050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KY998_03055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KY998_03060	COG0456	acetyltransferase
KY998_03065	COG1509	lysine 2,3-aminomutase activity
KY998_03075	COG4479	Belongs to the UPF0346 family
KY998_03090	COG0671	phosphoesterase, PA-phosphatase related
KY998_03110	COG0701	Predicted permease
KY998_03115	COG0813	purine-nucleoside phosphorylase activity
KY998_03120	COG1876	peptidase activity
KY998_03130	COG2226	methyltransferase
KY998_03140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KY998_03150	COG0400	carboxylic ester hydrolase activity
KY998_03155	COG0778	Nitroreductase
KY998_03160	COG1733	regulation of RNA biosynthetic process
KY998_03165	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_03175	COG4305	rare lipoprotein A
KY998_03185	COG2962	Rard protein
KY998_03195	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KY998_03200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KY998_03205	COG0534	Mate efflux family protein
KY998_03210	COG0791	NLP P60 protein
KY998_03210	COG1388	LysM domain
KY998_03215	COG2032	superoxide dismutase activity
KY998_03220	COG0714	Associated with various cellular activities
KY998_03225	COG4548	von Willebrand factor, type A
KY998_03230	COG0567	Dehydrogenase, E1 component
KY998_03235	COG0508	dehydrogenase complex catalyzes the overall conversion of
KY998_03240	COG0385	Bile acid
KY998_03255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KY998_03260	COG1657	PFAM Prenyltransferase squalene oxidase
KY998_03275	COG2814	Major facilitator Superfamily
KY998_03280	COG1012	belongs to the aldehyde dehydrogenase family
KY998_03295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KY998_03315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KY998_03320	COG2318	DinB family
KY998_03340	COG0574	Belongs to the PEP-utilizing enzyme family
KY998_03340	COG3848	Pyruvate phosphate dikinase
KY998_03350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KY998_03355	COG1280	lysine exporter protein (LysE YggA)
KY998_03370	COG2267	carboxylic ester hydrolase activity
KY998_03385	COG0402	S-adenosylhomocysteine deaminase activity
KY998_03405	COG2350	Protein conserved in bacteria
KY998_03440	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KY998_03455	COG5444	nuclease activity
KY998_03470	COG3383	formate dehydrogenase (NAD+) activity
KY998_03485	COG2315	Protein conserved in bacteria
KY998_03510	COG0514	ATP-dependent DNA helicase (RecQ)
KY998_03520	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KY998_03525	COG1619	proteins homologs of microcin C7 resistance protein MccF
KY998_03540	COG2322	membrane
KY998_03560	COG1086	Polysaccharide biosynthesis protein
KY998_03565	COG0741	lytic transglycosylase activity
KY998_03570	COG0531	amino acid
KY998_03585	COG0640	Transcriptional regulator
KY998_03595	COG2378	regulation of single-species biofilm formation
KY998_03610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KY998_03615	COG1309	transcriptional regulator
KY998_03645	COG1846	Transcriptional regulator
KY998_03650	COG1309	transcriptional regulator
KY998_03665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KY998_03680	COG0697	spore germination
KY998_03685	COG0531	amino acid
KY998_03700	COG2814	Major facilitator Superfamily
KY998_03705	COG1846	Transcriptional regulator
KY998_03710	COG0243	molybdopterin cofactor binding
KY998_03715	COG0477	Major facilitator Superfamily
KY998_03720	COG0574	Belongs to the PEP-utilizing enzyme family
KY998_03720	COG3848	Pyruvate phosphate dikinase
KY998_03735	COG1132	(ABC) transporter
KY998_03770	COG0070	glutamate synthase
KY998_03770	COG0069	glutamate synthase activity
KY998_03770	COG0067	glutamate synthase
KY998_03775	COG0493	'glutamate synthase
KY998_03790	COG0463	Glycosyl transferase, family 2
KY998_03795	COG2814	Major facilitator Superfamily
KY998_03800	COG4948	Mandelate Racemase Muconate Lactonizing
KY998_03810	COG1809	phosphosulfolactate synthase activity
KY998_03815	COG0175	sulfate reduction
KY998_03830	COG2323	membrane
KY998_03850	COG1733	regulation of RNA biosynthetic process
KY998_03860	COG1960	acyl-CoA dehydrogenase activity
KY998_03865	COG0318	PFAM AMP-dependent synthetase and ligase
KY998_03895	COG0439	Biotin carboxylase
KY998_03900	COG0511	ligase activity, forming carbon-carbon bonds
KY998_03905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KY998_03915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KY998_03930	COG0166	Belongs to the GPI family
KY998_03940	COG1252	NADH dehydrogenase
KY998_03945	COG1309	transcriptional regulator
KY998_03975	COG2027	D-alanyl-D-alanine carboxypeptidase
KY998_03985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KY998_03990	COG2404	hydrolase activity, acting on ester bonds
KY998_04010	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
KY998_04015	COG0640	Transcriptional regulator
KY998_04020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KY998_04025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KY998_04040	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KY998_04055	COG1312	Catalyzes the dehydration of D-mannonate
KY998_04060	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_04065	COG1725	Transcriptional regulator
KY998_04070	COG1131	(ABC) transporter
KY998_04095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KY998_04095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KY998_04095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KY998_04100	COG1482	cell wall glycoprotein biosynthetic process
KY998_04105	COG1960	acyl-CoA dehydrogenase activity
KY998_04110	COG2084	Dehydrogenase
KY998_04120	COG1024	Enoyl-CoA hydratase
KY998_04150	COG1114	Component of the transport system for branched-chain amino acids
KY998_04155	COG3420	alginic acid biosynthetic process
KY998_04180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KY998_04190	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KY998_04200	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KY998_04220	COG2223	nitrite transmembrane transporter activity
KY998_04225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KY998_04235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KY998_04240	COG0535	radical SAM domain protein
KY998_04255	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KY998_04260	COG1140	nitrate reductase beta subunit
KY998_04265	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KY998_04270	COG2181	nitrate reductase activity
KY998_04300	COG2160	L-arabinose isomerase activity
KY998_04315	COG1609	Transcriptional regulator
KY998_04320	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KY998_04325	COG0187	DNA topoisomerase II activity
KY998_04330	COG1832	CoA-binding protein
KY998_04335	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KY998_04340	COG4841	protein insertion into membrane
KY998_04360	COG0824	Thioesterase
KY998_04380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KY998_04385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KY998_04400	COG0071	Belongs to the small heat shock protein (HSP20) family
KY998_04410	COG4846	Membrane protein involved in cytochrome C biogenesis
KY998_04415	COG2201	protein-glutamate methylesterase activity
KY998_04420	COG0785	Cytochrome C biogenesis protein
KY998_04430	COG3763	UPF0154 protein
KY998_04440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KY998_04445	COG4224	UPF0291 protein
KY998_04450	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KY998_04455	COG1388	LysM domain
KY998_04460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KY998_04465	COG3209	COG3209 Rhs family protein
KY998_04490	COG0655	NAD(P)H dehydrogenase (quinone) activity
KY998_04495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KY998_04500	COG0346	lactoylglutathione lyase activity
KY998_04505	COG1846	Transcriptional regulator
KY998_04535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KY998_04550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KY998_04555	COG2076	Multidrug Resistance protein
KY998_04560	COG2076	Multidrug Resistance protein
KY998_04565	COG1309	transcriptional regulator
KY998_04605	COG1073	alpha beta
KY998_04610	COG0475	glutathione-regulated potassium exporter activity
KY998_04615	COG0490	domain, Protein
KY998_04660	COG0174	glutamine synthetase
KY998_04665	COG0789	Transcriptional regulator
KY998_04670	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KY998_04675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KY998_04695	COG3331	DNA recombination
KY998_04705	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
KY998_04725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KY998_04750	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KY998_04770	COG0756	dUTP diphosphatase activity
KY998_04780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KY998_04785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KY998_04805	COG1780	Probably involved in ribonucleotide reductase function
KY998_04880	COG3584	3D domain protein
KY998_04905	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KY998_04910	COG0358	DNA primase activity
KY998_04925	COG2887	Belongs to the helicase family. UvrD subfamily
KY998_04985	COG1793	dna ligase
KY998_05025	COG4474	Belongs to the UPF0398 family
KY998_05030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KY998_05070	COG0582	viral genome integration into host DNA
KY998_05100	COG1404	Belongs to the peptidase S8 family
KY998_05170	COG3655	Transcriptional regulator
KY998_05255	COG1404	Belongs to the peptidase S8 family
KY998_05325	COG4373	Mu-like prophage FluMu protein gp28
KY998_05415	COG0582	viral genome integration into host DNA
KY998_05475	COG1196	nuclear chromosome segregation
KY998_05475	COG0741	lytic transglycosylase activity
KY998_05475	COG0739	heme binding
KY998_05495	COG2433	Pfam Transposase IS66
KY998_05505	COG5434	Belongs to the glycosyl hydrolase 28 family
KY998_05510	COG5632	N-Acetylmuramoyl-L-alanine amidase
KY998_05535	COG0457	Tetratricopeptide repeat
KY998_05580	COG4282	regulation of fungal-type cell wall biogenesis
KY998_05615	COG1695	Transcriptional regulator
KY998_05625	COG0829	nickel cation binding
KY998_05630	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KY998_05635	COG0830	nickel cation binding
KY998_05640	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KY998_05650	COG0832	Belongs to the urease beta subunit family
KY998_05655	COG0831	urea catabolic process
KY998_05660	COG4413	Urea transporter
KY998_05670	COG0457	Tetratricopeptide repeat
KY998_05675	COG2814	Major facilitator Superfamily
KY998_05725	COG5444	nuclease activity
KY998_05730	COG4282	regulation of fungal-type cell wall biogenesis
KY998_05765	COG1309	transcriptional regulator
KY998_05800	COG0697	spore germination
KY998_05810	COG0735	belongs to the Fur family
KY998_05825	COG4112	unkown
KY998_05830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KY998_05835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KY998_05840	COG1780	Probably involved in ribonucleotide reductase function
KY998_05850	COG1923	regulation of RNA biosynthetic process
KY998_05855	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KY998_05870	COG2076	Multidrug Resistance protein
KY998_05875	COG2076	Multidrug Resistance protein
KY998_05880	COG1764	response to oxidative stress
KY998_05890	COG0702	epimerase
KY998_05895	COG3631	Ketosteroid isomerase-related protein
KY998_05900	COG1309	transcriptional regulator
KY998_05905	COG1388	LysM domain
KY998_05905	COG3858	chitin binding
KY998_05915	COG5577	PFAM Coat F domain
KY998_05920	COG0531	amino acid
KY998_05925	COG1819	glycosyl
KY998_05930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KY998_05935	COG0398	Pfam SNARE associated Golgi protein
KY998_05940	COG0393	Putative heavy-metal-binding
KY998_05960	COG2267	carboxylic ester hydrolase activity
KY998_05970	COG3263	regulation of cellular component size
KY998_05975	COG3619	membrane
KY998_05980	COG1231	oxidoreductase activity
KY998_06010	COG0523	cobalamin synthesis protein
KY998_06055	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KY998_06060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KY998_06065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KY998_06075	COG4550	Control of competence regulator ComK, YlbF/YmcA
KY998_06080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KY998_06090	COG1063	alcohol dehydrogenase
KY998_06100	COG2359	stage V sporulation protein S
KY998_06105	COG1692	metallophosphoesterase
KY998_06110	COG1418	mRNA catabolic process
KY998_06120	COG1546	Belongs to the CinA family
KY998_06120	COG1058	Belongs to the CinA family
KY998_06125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KY998_06130	COG1426	Protein conserved in bacteria
KY998_06145	COG0300	oxidoreductase activity
KY998_06150	COG0612	Peptidase, M16
KY998_06155	COG0612	Peptidase, M16
KY998_06165	COG2188	Transcriptional regulator
KY998_06170	COG1674	ftsk spoiiie
KY998_06170	COG4980	gas vesicle protein
KY998_06180	COG0740	serine-type endopeptidase activity
KY998_06185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KY998_06195	COG0527	aspartate kinase activity
KY998_06200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KY998_06205	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KY998_06210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KY998_06215	COG1873	PFAM PRC-barrel domain
KY998_06220	COG0612	Peptidase, M16
KY998_06235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KY998_06240	COG0196	riboflavin kinase activity
KY998_06245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KY998_06250	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KY998_06255	COG1550	Protein conserved in bacteria
KY998_06260	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KY998_06265	COG1358	cellular component organization or biogenesis
KY998_06270	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KY998_06275	COG0195	Participates in both transcription termination and antitermination
KY998_06280	COG0779	Required for maturation of 30S ribosomal subunits
KY998_06305	COG2176	DNA-directed DNA polymerase activity
KY998_06310	COG0442	prolyl-tRNA aminoacylation
KY998_06315	COG0750	zinc metalloprotease
KY998_06320	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KY998_06325	COG4589	Belongs to the CDS family
KY998_06330	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KY998_06335	COG0233	cytoplasmic translational termination
KY998_06340	COG0528	UMP kinase activity
KY998_06345	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KY998_06350	COG0052	Belongs to the universal ribosomal protein uS2 family
KY998_06360	COG1191	sigma factor activity
KY998_06365	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KY998_06370	COG1776	CheC inhibitor of MCP methylation
KY998_06375	COG0835	chemotaxis
KY998_06380	COG0643	Histidine kinase
KY998_06380	COG2198	Histidine kinase
KY998_06385	COG2201	protein-glutamate methylesterase activity
KY998_06390	COG0455	bacterial-type flagellum organization
KY998_06395	COG1419	protein localization to endoplasmic reticulum
KY998_06400	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KY998_06405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KY998_06410	COG1684	flagellar biosynthetic protein fliR
KY998_06415	COG1987	bacterial-type flagellum assembly
KY998_06420	COG1338	Plays a role in the flagellum-specific transport system
KY998_06425	COG3190	flagellar
KY998_06430	COG2201	protein-glutamate methylesterase activity
KY998_06435	COG1776	CheC inhibitor of MCP methylation
KY998_06435	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KY998_06440	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KY998_06445	COG1580	Controls the rotational direction of flagella during chemotaxis
KY998_06450	COG1582	Flagellar protein (FlbD)
KY998_06455	COG4786	Flagellar basal body rod
KY998_06460	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KY998_06465	COG3144	bacterial-type flagellum assembly
KY998_06475	COG2882	bacterial-type flagellum organization
KY998_06480	COG1157	protein secretion by the type III secretion system
KY998_06485	COG1317	bacterial-type flagellum organization
KY998_06490	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KY998_06495	COG1766	The M ring may be actively involved in energy transduction
KY998_06500	COG1677	Flagellar hook-basal body complex protein FliE
KY998_06505	COG1558	bacterial-type flagellum-dependent cell motility
KY998_06510	COG1815	bacterial-type flagellum-dependent cell motility
KY998_06515	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KY998_06520	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KY998_06525	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KY998_06530	COG4974	Belongs to the 'phage' integrase family
KY998_06535	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KY998_06540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KY998_06545	COG0758	DNA mediated transformation
KY998_06550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KY998_06555	COG0045	succinate-CoA ligase (ADP-forming) activity
KY998_06560	COG2257	FlhB HrpN YscU SpaS Family
KY998_06570	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KY998_06575	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KY998_06580	COG0335	large ribosomal subunit rRNA binding
KY998_06585	COG0336	Belongs to the RNA methyltransferase TrmD family
KY998_06590	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KY998_06600	COG1837	Belongs to the UPF0109 family
KY998_06605	COG0228	four-way junction DNA binding
KY998_06610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KY998_06615	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KY998_06620	COG0552	protein localization to endoplasmic reticulum
KY998_06625	COG1196	nuclear chromosome segregation
KY998_06630	COG0571	ribonuclease III activity
KY998_06635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KY998_06640	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_06645	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KY998_06650	COG0416	fatty acid biosynthetic process
KY998_06655	COG1349	DNA-binding transcription factor activity
KY998_06675	COG1461	Dihydroxyacetone kinase
KY998_06680	COG1302	Protein conserved in bacteria
KY998_06685	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KY998_06695	COG1564	THIamine pyrophosphokinase
KY998_06700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KY998_06705	COG1162	GTPase activity
KY998_06710	COG0515	serine threonine protein kinase
KY998_06710	COG2815	serine threonine protein kinase
KY998_06715	COG0631	protein serine/threonine phosphatase activity
KY998_06720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KY998_06725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KY998_06725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KY998_06730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KY998_06735	COG0242	peptide deformylase activity
KY998_06740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KY998_06745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KY998_06750	COG1758	RNA polymerase activity
KY998_06755	COG0194	GDP metabolic process
KY998_06760	COG2052	Domain of unknown function (DUF370)
KY998_06765	COG1561	YicC-like family, N-terminal region
KY998_06770	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KY998_06780	COG1648	precorrin-2 dehydrogenase activity
KY998_06785	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KY998_06795	COG0529	Catalyzes the synthesis of activated sulfate
KY998_06800	COG2046	Belongs to the sulfate adenylyltransferase family
KY998_06805	COG0306	phosphate transporter
KY998_06810	COG0175	sulfate reduction
KY998_06820	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KY998_06825	COG0284	orotidine-5'-phosphate decarboxylase activity
KY998_06830	COG0167	dihydroorotate dehydrogenase activity
KY998_06835	COG0543	2 iron, 2 sulfur cluster binding
KY998_06840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KY998_06845	COG0505	Belongs to the CarA family
KY998_06855	COG0540	Belongs to the ATCase OTCase family
KY998_06860	COG2233	PERMEase
KY998_06870	COG0564	pseudouridine synthase activity
KY998_06875	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KY998_06880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KY998_06885	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KY998_06890	COG3599	regulation of cell shape
KY998_06895	COG2302	S4 RNA-binding domain
KY998_06900	COG0762	integral membrane protein
KY998_06905	COG1799	cell septum assembly
KY998_06910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KY998_06915	COG1496	oxidoreductase activity
KY998_06920	COG1873	PFAM PRC-barrel domain
KY998_06925	COG0500	methyltransferase
KY998_06930	COG1119	ATPase activity
KY998_06935	COG1191	sigma factor activity
KY998_06950	COG1404	Belongs to the peptidase S8 family
KY998_06950	COG4412	M6 family metalloprotease domain protein
KY998_06960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KY998_06965	COG0849	cell division
KY998_06970	COG3856	small basic protein
KY998_06975	COG3879	Bacterial protein of unknown function (DUF881)
KY998_06980	COG3879	Bacterial protein of unknown function (DUF881)
KY998_06985	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KY998_06990	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KY998_06995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KY998_07010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KY998_07015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KY998_07025	COG0768	penicillin binding
KY998_07030	COG4839	cell division protein FtsL
KY998_07035	COG0275	rRNA processing
KY998_07040	COG2001	Belongs to the MraZ family
KY998_07045	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KY998_07050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KY998_07055	COG0454	-acetyltransferase
KY998_07065	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KY998_07070	COG1399	metal-binding, possibly nucleic acid-binding protein
KY998_07075	COG1323	Belongs to the UPF0348 family
KY998_07080	COG3480	Lon protease (S16) C-terminal proteolytic domain
KY998_07085	COG3314	Sporulation integral membrane protein YlbJ
KY998_07090	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KY998_07095	COG0742	ribosomal rna small subunit methyltransferase
KY998_07100	COG4471	UPF0298 protein
KY998_07105	COG3679	Belongs to the UPF0342 family
KY998_07120	COG2340	Cysteine-rich secretory protein family
KY998_07125	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KY998_07135	COG3336	cytochrome c oxidase
KY998_07140	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KY998_07145	COG1845	cytochrome c oxidase, subunit III
KY998_07150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KY998_07155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KY998_07155	COG2010	Cytochrome c
KY998_07160	COG0109	protoheme IX farnesyltransferase activity
KY998_07165	COG1612	heme a metabolic process
KY998_07170	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KY998_07175	COG0772	Belongs to the SEDS family
KY998_07180	COG4838	Belongs to the UPF0358 family
KY998_07185	COG2066	Belongs to the glutaminase family
KY998_07190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KY998_07195	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KY998_07205	COG4896	Protein conserved in bacteria
KY998_07210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KY998_07215	COG1846	Transcriptional regulator
KY998_07225	COG1217	gtp-binding protein TYPA
KY998_07240	COG1595	DNA-templated transcription, initiation
KY998_07260	COG0483	inositol monophosphate 1-phosphatase activity
KY998_07270	COG4493	Belongs to the UPF0637 family
KY998_07275	COG4476	Belongs to the UPF0223 family
KY998_07280	COG1982	Orn Lys Arg decarboxylase major
KY998_07290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KY998_07295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KY998_07300	COG0508	dehydrogenase complex catalyzes the overall conversion of
KY998_07305	COG0022	dehydrogenase e1 component
KY998_07310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KY998_07315	COG0497	DNA recombination
KY998_07325	COG0242	peptide deformylase activity
KY998_07335	COG5503	Protein of unknown function (DUF1447)
KY998_07340	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KY998_07345	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KY998_07360	COG2002	toxin-antitoxin pair type II binding
KY998_07365	COG1077	Cell shape determining protein MreB Mrl
KY998_07375	COG2309	aminopeptidase activity
KY998_07385	COG0488	(ABC) transporter
KY998_07405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KY998_07405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KY998_07405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KY998_07415	COG1349	DNA-binding transcription factor activity
KY998_07420	COG0577	efflux transmembrane transporter activity
KY998_07425	COG1136	(ABC) transporter
KY998_07455	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KY998_07460	COG0314	molybdopterin synthase activity
KY998_07465	COG1763	Mo-molybdopterin cofactor biosynthetic process
KY998_07470	COG0303	'Molybdopterin
KY998_07480	COG0746	molybdenum cofactor guanylyltransferase activity
KY998_07495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KY998_07500	COG0450	alkyl hydroperoxide reductase
KY998_07510	COG1473	amidohydrolase
KY998_07515	COG2171	N-acyltransferase activity
KY998_07520	COG0716	FMN binding
KY998_07530	COG0716	FMN binding
KY998_07535	COG0583	DNA-binding transcription factor activity
KY998_07540	COG0517	IMP dehydrogenase activity
KY998_07550	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KY998_07560	COG4703	Protein of unknown function (DUF1797)
KY998_07570	COG2200	EAL domain
KY998_07580	COG1408	metallophosphoesterase
KY998_07585	COG1376	ErfK ybiS ycfS ynhG family protein
KY998_07590	COG2814	Major facilitator Superfamily
KY998_07600	COG0835	chemotaxis
KY998_07600	COG0784	Response regulator, receiver
KY998_07610	COG1714	RDD family
KY998_07625	COG4191	Histidine kinase
KY998_07630	COG0768	penicillin binding
KY998_07635	COG2340	Cysteine-rich secretory protein family
KY998_07645	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_07650	COG0840	transmembrane signaling receptor activity
KY998_07655	COG0456	acetyltransferase
KY998_07660	COG1533	DNA photolyase activity
KY998_07670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KY998_07675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KY998_07680	COG1263	PTS System
KY998_07680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KY998_07680	COG2190	(PTS) system
KY998_07685	COG3711	transcriptional antiterminator
KY998_07690	COG1609	Transcriptional regulator
KY998_07700	COG0006	proline dipeptidase activity
KY998_07710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KY998_07715	COG2244	polysaccharide biosynthetic process
KY998_07720	COG3773	Cell wall hydrolase
KY998_07730	COG4873	Protein conserved in bacteria
KY998_07765	COG3655	Transcriptional regulator
KY998_07770	COG3739	integral membrane protein
KY998_07780	COG0457	Tetratricopeptide repeat
KY998_07785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KY998_07790	COG0602	queuosine metabolic process
KY998_07795	COG0720	synthase
KY998_07800	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KY998_07805	COG3949	Membrane
KY998_07810	COG0542	response to heat
KY998_07815	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KY998_07820	COG1360	Flagellar Motor Protein
KY998_07825	COG1846	Transcriptional regulator
KY998_07830	COG3852	Histidine kinase
KY998_07840	COG3339	Conserved Protein
KY998_07845	COG0346	lactoylglutathione lyase activity
KY998_07850	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KY998_07855	COG0235	Class ii aldolase
KY998_07855	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KY998_07860	COG0235	Class ii aldolase
KY998_07860	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KY998_07865	COG1850	ribulose-bisphosphate carboxylase activity
KY998_07870	COG0436	Aminotransferase
KY998_07875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KY998_07880	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KY998_07885	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KY998_07895	COG5002	protein histidine kinase activity
KY998_07900	COG3594	Acyltransferase
KY998_07920	COG0768	penicillin binding
KY998_07925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KY998_07930	COG0501	Belongs to the peptidase M48B family
KY998_07950	COG1191	sigma factor activity
KY998_07960	COG0586	Pfam SNARE associated Golgi protein
KY998_07965	COG3300	MHYT domain
KY998_07965	COG5001	Diguanylate cyclase
KY998_07970	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KY998_07975	COG1793	dna ligase
KY998_07975	COG3285	dna ligase
KY998_07995	COG0789	Transcriptional regulator
KY998_08005	COG2239	Acts as a magnesium transporter
KY998_08015	COG1404	Belongs to the peptidase S8 family
KY998_08020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KY998_08035	COG0406	alpha-ribazole phosphatase activity
KY998_08040	COG0590	tRNA wobble adenosine to inosine editing
KY998_08050	COG1764	response to oxidative stress
KY998_08055	COG1846	Transcriptional regulator
KY998_08065	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KY998_08070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KY998_08075	COG0788	formyltetrahydrofolate deformylase activity
KY998_08080	COG2076	Multidrug Resistance protein
KY998_08085	COG2076	Multidrug Resistance protein
KY998_08090	COG2318	DinB family
KY998_08110	COG3866	Pectate lyase
KY998_08115	COG2323	membrane
KY998_08120	COG1607	acyl-coa hydrolase
KY998_08125	COG1834	amidinotransferase
KY998_08140	COG4948	Mandelate Racemase Muconate Lactonizing
KY998_08145	COG1619	proteins homologs of microcin C7 resistance protein MccF
KY998_08150	COG4166	transmembrane transport
KY998_08155	COG0444	Belongs to the ABC transporter superfamily
KY998_08160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KY998_08165	COG0601	transmembrane transport
KY998_08170	COG2362	D-Aminopeptidase
KY998_08175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KY998_08190	COG0531	amino acid
KY998_08195	COG0395	ABC-type sugar transport system, permease component
KY998_08200	COG4209	transmembrane transport
KY998_08205	COG1653	transport
KY998_08215	COG1874	Beta-galactosidase
KY998_08220	COG2755	lipolytic protein G-D-S-L family
KY998_08230	COG3401	FG-GAP repeat protein
KY998_08245	COG3401	FG-GAP repeat protein
KY998_08250	COG5578	integral membrane protein
KY998_08260	COG2755	lipolytic protein G-D-S-L family
KY998_08270	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KY998_08280	COG1175	transmembrane transport
KY998_08285	COG1653	transport
KY998_08290	COG2207	Transcriptional regulator
KY998_08290	COG4753	response regulator
KY998_08300	COG5578	integral membrane protein
KY998_08305	COG0405	Gamma-glutamyltransferase
KY998_08310	COG1392	Phosphate transport regulator
KY998_08315	COG0306	phosphate transporter
KY998_08330	COG2271	Major facilitator Superfamily
KY998_08340	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_08345	COG1312	Catalyzes the dehydration of D-mannonate
KY998_08350	COG1063	alcohol dehydrogenase
KY998_08355	COG1802	Transcriptional regulator
KY998_08395	COG3778	Protein conserved in bacteria
KY998_08400	COG3299	homolog of phage Mu protein gp47
KY998_08405	COG3628	GPW Gp25 family protein
KY998_08415	COG4193	domain, Protein
KY998_08420	COG1652	LysM domain
KY998_08425	COG3953	SLT domain
KY998_08425	COG5412	phage tail tape measure protein
KY998_08475	COG4653	Phage capsid family
KY998_08480	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KY998_08485	COG5518	Phage portal protein
KY998_08490	COG1783	phage Terminase large subunit
KY998_08495	COG5484	DNA packaging
KY998_08495	COG3728	DNA packaging
KY998_08500	COG1595	DNA-templated transcription, initiation
KY998_08520	COG1484	DNA-dependent DNA replication
KY998_08525	COG1522	sequence-specific DNA binding
KY998_08540	COG1396	sequence-specific DNA binding
KY998_08545	COG2856	Zn peptidase
KY998_08550	COG4195	phage-related replication protein
KY998_08565	COG1309	transcriptional regulator
KY998_08570	COG2814	Major facilitator Superfamily
KY998_08575	COG3584	3D domain protein
KY998_08575	COG1388	LysM domain
KY998_08585	COG0346	lactoylglutathione lyase activity
KY998_08595	COG0583	DNA-binding transcription factor activity
KY998_08600	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KY998_08605	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KY998_08610	COG0583	DNA-binding transcription factor activity
KY998_08620	COG0110	maltose O-acetyltransferase activity
KY998_08675	COG3507	Belongs to the glycosyl hydrolase 43 family
KY998_08685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KY998_08700	COG5505	Protein of unknown function (DUF819)
KY998_08705	COG0626	cystathionine gamma-synthase activity
KY998_08730	COG2382	esterase
KY998_08735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KY998_08740	COG2153	protein acetylation
KY998_08745	COG2246	polysaccharide biosynthetic process
KY998_08750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KY998_08760	COG0586	Pfam SNARE associated Golgi protein
KY998_08770	COG0210	DNA helicase
KY998_08825	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KY998_08830	COG0351	phosphomethylpyrimidine kinase
KY998_08835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KY998_08840	COG2022	thiamine diphosphate biosynthetic process
KY998_08845	COG2104	thiamine diphosphate biosynthetic process
KY998_08855	COG0352	thiamine-phosphate diphosphorylase activity
KY998_08860	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KY998_08865	COG0475	glutathione-regulated potassium exporter activity
KY998_08865	COG0569	domain protein
KY998_08870	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KY998_08880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KY998_08885	COG2357	RelA SpoT domain protein
KY998_08895	COG4116	CYTH
KY998_08900	COG0741	lytic transglycosylase activity
KY998_08905	COG2346	COG2346, Truncated hemoglobins
KY998_08910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KY998_08920	COG1164	Oligoendopeptidase f
KY998_08925	COG4469	Competence protein
KY998_08930	COG3290	protein histidine kinase activity
KY998_08960	COG4862	establishment of competence for transformation
KY998_08970	COG0861	Integral membrane protein TerC family
KY998_08975	COG1393	Belongs to the ArsC family
KY998_08980	COG0456	acetyltransferase
KY998_08995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KY998_09005	COG4166	transmembrane transport
KY998_09010	COG0180	Tryptophanyl-tRNA synthetase
KY998_09025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KY998_09030	COG0601	transmembrane transport
KY998_09050	COG5504	Zn-dependent protease
KY998_09060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KY998_09065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KY998_09080	COG1744	ABC transporter substrate-binding protein PnrA-like
KY998_09090	COG2267	carboxylic ester hydrolase activity
KY998_09105	COG1968	undecaprenyl-diphosphatase activity
KY998_09110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KY998_09120	COG0505	Belongs to the CarA family
KY998_09130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KY998_09135	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KY998_09140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KY998_09145	COG2151	metal-sulfur cluster biosynthetic enzyme
KY998_09150	COG1073	alpha beta
KY998_09155	COG0561	phosphatase activity
KY998_09165	COG0516	GMP reductase activity
KY998_09175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KY998_09195	COG2996	Protein conserved in bacteria
KY998_09200	COG1666	GTP binding
KY998_09210	COG0646	methionine synthase
KY998_09210	COG1410	methionine synthase
KY998_09215	COG2378	regulation of single-species biofilm formation
KY998_09225	COG2153	protein acetylation
KY998_09250	COG0076	glutamate decarboxylase activity
KY998_09260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KY998_09265	COG1279	arginine transmembrane transporter activity
KY998_09285	COG0673	inositol 2-dehydrogenase activity
KY998_09290	COG1609	Transcriptional regulator
KY998_09300	COG1917	Cupin 2, conserved barrel domain protein
KY998_09300	COG2207	Transcriptional regulator
KY998_09305	COG0534	Mate efflux family protein
KY998_09310	COG0347	Belongs to the P(II) protein family
KY998_09315	COG0004	ammonium transporteR
KY998_09320	COG0367	asparagine synthase
KY998_09340	COG0179	Fumarylacetoacetate (FAA) hydrolase
KY998_09350	COG5337	Spore coat protein CotH
KY998_09395	COG0419	ATPase involved in DNA repair
KY998_09420	COG4149	molybdate abc transporter
KY998_09425	COG0725	ABC transporter, periplasmic molybdate-binding protein
KY998_09430	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KY998_09450	COG4533	DNA binding
KY998_09455	COG0477	Major facilitator Superfamily
KY998_09455	COG2814	Major facilitator Superfamily
KY998_09460	COG0318	PFAM AMP-dependent synthetase and ligase
KY998_09465	COG3546	catalase activity
KY998_09480	COG3180	Ammonia monooxygenase
KY998_09485	COG1486	melibiose metabolic process
KY998_09490	COG0395	ABC-type sugar transport system, permease component
KY998_09495	COG1175	transmembrane transport
KY998_09515	COG0457	Tetratricopeptide repeat
KY998_09525	COG2814	Major facilitator Superfamily
KY998_09540	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KY998_09545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KY998_09550	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KY998_09555	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KY998_09560	COG3257	ureidoglycine aminohydrolase activity
KY998_09565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KY998_09570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KY998_09575	COG2508	Transcriptional regulator
KY998_09590	COG0681	Belongs to the peptidase S26 family
KY998_09595	COG0398	Pfam SNARE associated Golgi protein
KY998_09605	COG4903	ComK protein
KY998_09615	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_09620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KY998_09620	COG0723	plastoquinol--plastocyanin reductase activity
KY998_09630	COG1268	BioY protein
KY998_09635	COG0318	PFAM AMP-dependent synthetase and ligase
KY998_09640	COG0183	Belongs to the thiolase family
KY998_09645	COG0406	alpha-ribazole phosphatase activity
KY998_09650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KY998_09655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KY998_09665	COG0697	spore germination
KY998_09675	COG0501	Belongs to the peptidase M48B family
KY998_09690	COG1396	sequence-specific DNA binding
KY998_09700	COG0318	PFAM AMP-dependent synthetase and ligase
KY998_09705	COG0095	Lipoate-protein ligase
KY998_09710	COG1234	tRNA 3'-trailer cleavage
KY998_09740	COG1511	domain protein
KY998_09745	COG1309	transcriptional regulator
KY998_09750	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KY998_09755	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KY998_09760	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KY998_09765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KY998_09770	COG2329	Antibiotic biosynthesis monooxygenase
KY998_09775	COG3069	C4-dicarboxylate transmembrane transporter activity
KY998_09780	COG1473	amidohydrolase
KY998_09790	COG4473	ABC transporter
KY998_09795	COG1131	(ABC) transporter
KY998_09800	COG0537	adenosine 5'-monophosphoramidase activity
KY998_09805	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KY998_09820	COG4980	gas vesicle protein
KY998_09825	COG1846	Transcriptional regulator
KY998_09855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KY998_09865	COG3481	metal-dependent phosphohydrolase, HD sub domain
KY998_09870	COG4717	serine-type aminopeptidase activity
KY998_09875	COG0420	3'-5' exonuclease activity
KY998_09880	COG1668	transmembrane transport
KY998_09885	COG4152	abc transporter atp-binding protein
KY998_09910	COG1024	Enoyl-CoA hydratase
KY998_09915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KY998_09925	COG3679	Belongs to the UPF0342 family
KY998_09930	COG4399	Belongs to the UPF0754 family
KY998_09940	COG0189	ligase activity
KY998_09950	COG2508	Transcriptional regulator
KY998_09955	COG3842	ATPase activity
KY998_09975	COG0702	epimerase
KY998_09980	COG1132	(ABC) transporter
KY998_09990	COG0589	response to stress
KY998_10015	COG2017	converts alpha-aldose to the beta-anomer
KY998_10020	COG1757	Na H antiporter
KY998_10030	COG0726	polysaccharide deacetylase
KY998_10045	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KY998_10050	COG0668	transmembrane transport
KY998_10065	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KY998_10090	COG1253	flavin adenine dinucleotide binding
KY998_10095	COG0789	Transcriptional regulator
KY998_10100	COG1253	flavin adenine dinucleotide binding
KY998_10115	COG3152	Membrane
KY998_10120	COG0204	Acyl-transferase
KY998_10125	COG0667	Aldo Keto reductase
KY998_10130	COG0662	Cupin 2, conserved barrel domain protein
KY998_10135	COG1595	DNA-templated transcription, initiation
KY998_10190	COG0733	neurotransmitter:sodium symporter activity
KY998_10195	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_10200	COG2133	pyrroloquinoline quinone binding
KY998_10205	COG0372	Belongs to the citrate synthase family
KY998_10210	COG0583	DNA-binding transcription factor activity
KY998_10220	COG2719	SpoVR family
KY998_10225	COG1017	nitric oxide dioxygenase activity
KY998_10225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KY998_10230	COG1959	2 iron, 2 sulfur cluster binding
KY998_10245	COG0431	NADPH-dependent FMN reductase
KY998_10250	COG2197	response regulator
KY998_10255	COG4585	Histidine kinase
KY998_10255	COG2203	Gaf domain
KY998_10270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KY998_10275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KY998_10285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KY998_10290	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KY998_10295	COG0604	alcohol dehydrogenase
KY998_10310	COG2116	formate transmembrane transporter activity
KY998_10315	COG0488	(ABC) transporter
KY998_10325	COG3153	acetyltransferase
KY998_10325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KY998_10335	COG0517	IMP dehydrogenase activity
KY998_10345	COG0564	pseudouridine synthase activity
KY998_10360	COG3764	Sortase (surface protein transpeptidase)
KY998_10365	COG4085	toxin activity
KY998_10365	COG1525	nuclease
KY998_10365	COG0737	Belongs to the 5'-nucleotidase family
KY998_10370	COG5002	protein histidine kinase activity
KY998_10375	COG5577	PFAM Coat F domain
KY998_10400	COG1823	symporter activity
KY998_10405	COG1464	Belongs to the NlpA lipoprotein family
KY998_10410	COG2011	ABC-type metal ion transport system permease component
KY998_10415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KY998_10420	COG1278	Cold shock
KY998_10425	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KY998_10430	COG1131	(ABC) transporter
KY998_10440	COG1725	Transcriptional regulator
KY998_10455	COG0655	NAD(P)H dehydrogenase (quinone) activity
KY998_10460	COG2814	Major facilitator Superfamily
KY998_10465	COG1566	PFAM secretion protein HlyD family protein
KY998_10470	COG2718	Belongs to the UPF0229 family
KY998_10475	COG2766	serine protein kinase
KY998_10485	COG1664	Polymer-forming cytoskeletal
KY998_10490	COG0789	Transcriptional regulator
KY998_10495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KY998_10505	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KY998_10510	COG3382	B3 4 domain protein
KY998_10520	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KY998_10540	COG1137	ATPase activity
KY998_10550	COG1476	TRANSCRIPTIONal
KY998_10560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KY998_10565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KY998_10570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KY998_10580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KY998_10585	COG0710	3-dehydroquinate dehydratase activity
KY998_10605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KY998_10650	COG5444	nuclease activity
KY998_10690	COG5434	Belongs to the glycosyl hydrolase 28 family
KY998_10695	COG1705	Flagellar rod assembly protein muramidase FlgJ
KY998_10705	COG3953	SLT domain
KY998_10705	COG5280	Phage tail tape measure protein TP901
KY998_10765	COG1802	Transcriptional regulator
KY998_10765	COG4626	Terminase
KY998_10795	COG0582	viral genome integration into host DNA
KY998_11095	COG1793	dna ligase
KY998_11145	COG3584	3D domain protein
KY998_11150	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KY998_11160	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KY998_11175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KY998_11180	COG1780	Probably involved in ribonucleotide reductase function
KY998_11200	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KY998_11220	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KY998_11220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KY998_11350	COG4974	Belongs to the 'phage' integrase family
KY998_11455	COG0735	belongs to the Fur family
KY998_11460	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KY998_11475	COG4129	membrane
KY998_11485	COG0601	transmembrane transport
KY998_11500	COG0444	Belongs to the ABC transporter superfamily
KY998_11505	COG1132	(ABC) transporter
KY998_11510	COG3557	Belongs to the UPF0374 family
KY998_11525	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_11535	COG1194	a g-specific adenine glycosylase
KY998_11540	COG1988	membrane-bound metal-dependent
KY998_11545	COG4485	Bacterial membrane protein, YfhO
KY998_11550	COG0463	Glycosyl transferase, family 2
KY998_11575	COG2137	regulation of response to DNA damage stimulus
KY998_11580	COG1090	epimerase
KY998_11600	COG0778	Nitroreductase
KY998_11605	COG0384	phenazine biosynthesis protein PhzF
KY998_11610	COG0392	lysyltransferase activity
KY998_11610	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KY998_11620	COG1051	belongs to the nudix hydrolase family
KY998_11625	COG2249	NAD(P)H dehydrogenase (quinone) activity
KY998_11630	COG1653	transport
KY998_11635	COG2207	Transcriptional regulator
KY998_11635	COG1917	Cupin 2, conserved barrel domain protein
KY998_11640	COG3507	Belongs to the glycosyl hydrolase 43 family
KY998_11650	COG2514	catechol 2,3-dioxygenase activity
KY998_11655	COG2259	Doxx family
KY998_11660	COG1733	regulation of RNA biosynthetic process
KY998_11675	COG1263	PTS System
KY998_11675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KY998_11680	COG1737	Transcriptional regulator
KY998_11685	COG1486	melibiose metabolic process
KY998_11690	COG1742	UPF0060 membrane protein
KY998_11695	COG3284	Transcriptional regulator
KY998_11700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KY998_11710	COG0022	dehydrogenase e1 component
KY998_11725	COG5609	conserved protein (DUF2294)
KY998_11730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KY998_11735	COG3002	Belongs to the UPF0753 family
KY998_11740	COG0288	reversible hydration of carbon dioxide
KY998_11745	COG3711	transcriptional antiterminator
KY998_11750	COG1263	PTS System
KY998_11750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KY998_11760	COG0477	Major facilitator Superfamily
KY998_11770	COG1819	glycosyl
KY998_11790	COG4637	Psort location Cytoplasmic, score
KY998_11795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KY998_11800	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KY998_11815	COG0371	Dehydrogenase
KY998_11830	COG0535	radical SAM domain protein
KY998_11840	COG0387	Pfam Sodium calcium exchanger
KY998_11850	COG0477	Major facilitator Superfamily
KY998_11855	COG1295	ribonuclease BN
KY998_11860	COG4980	gas vesicle protein
KY998_11865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KY998_11870	COG1115	amino acid carrier protein
KY998_11875	COG4840	Belongs to the UPF0435 family
KY998_11880	COG0693	protein deglycase activity
KY998_11885	COG0737	Belongs to the 5'-nucleotidase family
KY998_11890	COG0778	Nitroreductase
KY998_11895	COG1733	regulation of RNA biosynthetic process
KY998_11910	COG0673	inositol 2-dehydrogenase activity
KY998_11920	COG0457	Tetratricopeptide repeat
KY998_11920	COG0463	Glycosyl transferase, family 2
KY998_11925	COG1215	transferase activity, transferring glycosyl groups
KY998_11935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KY998_11940	COG1045	serine acetyltransferase
KY998_11945	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KY998_11970	COG2188	Transcriptional regulator
KY998_11980	COG1263	PTS System
KY998_11980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KY998_11985	COG1115	amino acid carrier protein
KY998_11995	COG1368	sulfuric ester hydrolase activity
KY998_12000	COG0024	Methionine aminopeptidase
KY998_12020	COG1254	Belongs to the acylphosphatase family
KY998_12025	COG0640	Transcriptional regulator
KY998_12030	COG5658	integral membrane protein
KY998_12035	COG3858	chitin binding
KY998_12040	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KY998_12050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KY998_12075	COG1136	(ABC) transporter
KY998_12085	COG0471	metal ion transport
KY998_12100	COG2130	NADP-dependent
KY998_12115	COG2814	Major facilitator Superfamily
KY998_12120	COG0789	Transcriptional regulator
KY998_12130	COG2124	cytochrome p450
KY998_12135	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KY998_12140	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KY998_12145	COG0156	8-amino-7-oxononanoate synthase activity
KY998_12150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KY998_12155	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KY998_12160	COG0523	cobalamin synthesis protein
KY998_12175	COG1469	GTP cyclohydrolase I activity
KY998_12180	COG0640	Transcriptional regulator
KY998_12190	COG0583	DNA-binding transcription factor activity
KY998_12195	COG0488	(ABC) transporter
KY998_12205	COG1309	transcriptional regulator
KY998_12210	COG0109	protoheme IX farnesyltransferase activity
KY998_12215	COG0840	transmembrane signaling receptor activity
KY998_12255	COG0217	transcriptional regulatory protein
KY998_12260	COG0697	spore germination
KY998_12265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KY998_12270	COG0697	spore germination
KY998_12275	COG3586	endonuclease activity
KY998_12280	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
KY998_12280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KY998_12300	COG3711	transcriptional antiterminator
KY998_12345	COG1957	nucleoside hydrolase
KY998_12350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KY998_12360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KY998_12365	COG1309	transcriptional regulator
KY998_12370	COG4124	Belongs to the glycosyl hydrolase 26 family
KY998_12385	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KY998_12390	COG0154	amidase activity
KY998_12395	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KY998_12400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KY998_12405	COG1285	pathogenesis
KY998_12415	COG3457	Alanine racemase
KY998_12420	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KY998_12425	COG0626	cystathionine gamma-synthase activity
KY998_12430	COG1735	metal-dependent hydrolase with the TIM-barrel fold
KY998_12450	COG2188	Transcriptional regulator
KY998_12455	COG4851	CamS sex pheromone cAM373 precursor
KY998_12460	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KY998_12465	COG0210	DNA helicase
KY998_12470	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KY998_12475	COG4496	protein, YerC YecD
KY998_12480	COG1470	cell adhesion involved in biofilm formation
KY998_12485	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KY998_12510	COG2124	cytochrome p450
KY998_12520	COG0151	Belongs to the GarS family
KY998_12525	COG0138	bifunctional purine biosynthesis protein purh
KY998_12535	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KY998_12540	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KY998_12545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KY998_12555	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KY998_12560	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KY998_12565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KY998_12570	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KY998_12575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KY998_12585	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KY998_12600	COG2252	PERMEase
KY998_12610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KY998_12610	COG0519	Catalyzes the synthesis of GMP from XMP
KY998_12615	COG1305	Transglutaminase-like
KY998_12620	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KY998_12625	COG0714	Associated with various cellular activities
KY998_12630	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KY998_12650	COG2132	Multicopper oxidase
KY998_12660	COG0702	epimerase
KY998_12685	COG0823	Involved in the tonB-independent uptake of proteins
KY998_12690	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KY998_12705	COG1846	Transcriptional regulator
KY998_12710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KY998_12715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KY998_12720	COG0366	Alpha amylase catalytic
KY998_12725	COG1554	hydrolase, family 65, central catalytic
KY998_12730	COG5521	maltodextrose utilization protein MalA
KY998_12735	COG3833	ABC-type maltose transport systems, permease component
KY998_12740	COG1175	transmembrane transport
KY998_12745	COG2182	Extracellular solute-binding protein
KY998_12750	COG0366	Alpha amylase catalytic
KY998_12770	COG0726	polysaccharide deacetylase
KY998_12800	COG0772	Belongs to the SEDS family
KY998_12805	COG3339	Conserved Protein
KY998_12810	COG1280	lysine exporter protein (LysE YggA)
KY998_12815	COG1378	Sugar-specific transcriptional regulator TrmB
KY998_12830	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KY998_12835	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KY998_12840	COG1842	Phage shock protein A
KY998_12845	COG2814	Major facilitator Superfamily
KY998_12850	COG2272	Belongs to the type-B carboxylesterase lipase family
KY998_12855	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KY998_12875	COG1309	transcriptional regulator
KY998_12905	COG2720	vancomycin resistance protein
KY998_12915	COG0459	protein refolding
KY998_12920	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KY998_12925	COG1266	CAAX protease self-immunity
KY998_12935	COG0805	protein transport
KY998_12940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KY998_12950	COG0315	cyclic pyranopterin monophosphate synthase activity
KY998_12960	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KY998_12965	COG0456	acetyltransferase
KY998_12970	COG1214	PFAM Peptidase M22, glycoprotease
KY998_12975	COG0802	atpase or kinase
KY998_12980	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KY998_13020	COG2814	Major facilitator Superfamily
KY998_13025	COG3764	Sortase (surface protein transpeptidase)
KY998_13035	COG3279	Response regulator of the LytR AlgR family
KY998_13050	COG0745	RESPONSE REGULATOR receiver
KY998_13050	COG2972	Histidine kinase
KY998_13055	COG1979	alcohol dehydrogenase
KY998_13065	COG0494	nUDIX hydrolase
KY998_13070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KY998_13070	COG2755	lipolytic protein G-D-S-L family
KY998_13080	COG1595	DNA-templated transcription, initiation
KY998_13085	COG5566	PFAM Mor transcription activator
KY998_13090	COG0596	Alpha beta hydrolase
KY998_13105	COG1113	amino acid transport
KY998_13110	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KY998_13120	COG1733	regulation of RNA biosynthetic process
KY998_13125	COG3545	Serine hydrolase
KY998_13150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KY998_13155	COG1733	regulation of RNA biosynthetic process
KY998_13165	COG2808	Putative FMN-binding domain
KY998_13170	COG0456	acetyltransferase
KY998_13175	COG1846	Transcriptional regulator
KY998_13180	COG2364	Membrane
KY998_13205	COG1278	Cold shock
KY998_13210	COG3239	Fatty acid desaturase
KY998_13215	COG0726	polysaccharide deacetylase
KY998_13240	COG0582	viral genome integration into host DNA
KY998_13280	COG3091	SprT-like family
KY998_13300	COG1309	transcriptional regulator
KY998_13305	COG2183	response to ionizing radiation
KY998_13310	COG2208	phosphoserine phosphatase activity
KY998_13315	COG1191	sigma factor activity
KY998_13330	COG2208	phosphoserine phosphatase activity
KY998_13335	COG2172	sigma factor antagonist activity
KY998_13340	COG1366	Belongs to the anti-sigma-factor antagonist family
KY998_13345	COG1366	Belongs to the anti-sigma-factor antagonist family
KY998_13350	COG2337	Toxic component of a toxin-antitoxin (TA) module
KY998_13355	COG0864	Transcriptional regulator
KY998_13360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KY998_13365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KY998_13370	COG0705	Rhomboid family
KY998_13375	COG3428	Bacterial PH domain
KY998_13380	COG3402	PFAM membrane-flanked domain
KY998_13385	COG0513	Belongs to the DEAD box helicase family
KY998_13395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KY998_13400	COG1181	Belongs to the D-alanine--D-alanine ligase family
KY998_13405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KY998_13420	COG1960	acyl-CoA dehydrogenase activity
KY998_13430	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KY998_13435	COG1131	(ABC) transporter
KY998_13440	COG1301	dicarboxylic acid transport
KY998_13445	COG0628	permease
KY998_13455	COG0662	Cupin 2, conserved barrel domain protein
KY998_13465	COG2217	Heavy metal translocating P-type atpase
KY998_13470	COG4876	unkown
KY998_13480	COG1027	Aspartate ammonia-lyase
KY998_13485	COG2261	transglycosylase associated protein
KY998_13490	COG1914	H( )-stimulated, divalent metal cation uptake system
KY998_13495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KY998_13515	COG1605	Chorismate mutase
KY998_13520	COG0512	Glutamine amidotransferase of anthranilate synthase
KY998_13520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KY998_13525	COG0287	Prephenate dehydrogenase
KY998_13530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KY998_13530	COG0551	DNA topoisomerase type I activity
KY998_13535	COG1522	sequence-specific DNA binding
KY998_13545	COG2814	Major facilitator Superfamily
KY998_13560	COG3871	stress protein (general stress protein 26)
KY998_13570	COG1917	Cupin 2, conserved barrel domain protein
KY998_13575	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_13580	COG3711	transcriptional antiterminator
KY998_13585	COG0246	Mannitol dehydrogenase
KY998_13590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KY998_13595	COG2213	PTS system mannitol-specific
KY998_13600	COG2755	lipolytic protein G-D-S-L family
KY998_13605	COG1414	Transcriptional regulator
KY998_13610	COG1984	allophanate hydrolase subunit 2
KY998_13615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KY998_13620	COG4336	lyase activity
KY998_13625	COG1914	H( )-stimulated, divalent metal cation uptake system
KY998_13630	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KY998_13635	COG0561	phosphatase activity
KY998_13640	COG3958	Transketolase
KY998_13645	COG3959	Transketolase, thiamine diphosphate binding domain
KY998_13660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KY998_13670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KY998_13675	COG0471	metal ion transport
KY998_13680	COG1802	Transcriptional regulator
KY998_13685	COG1587	Uroporphyrinogen-III synthase
KY998_13685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KY998_13690	COG2146	nitrite reductase [NAD(P)H] activity
KY998_13695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KY998_13705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KY998_13710	COG1349	DNA-binding transcription factor activity
KY998_13715	COG2372	response to copper ion
KY998_13715	COG1276	copper resistance
KY998_13720	COG4549	nuclear export factor GLE1
KY998_13730	COG0697	spore germination
KY998_13735	COG1012	belongs to the aldehyde dehydrogenase family
KY998_13745	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KY998_13755	COG0640	Transcriptional regulator
KY998_13760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KY998_13765	COG0778	Nitroreductase
KY998_13775	COG1309	transcriptional regulator
KY998_13780	COG2814	Major facilitator Superfamily
KY998_13785	COG4607	ABC-type enterochelin transport system periplasmic component
KY998_13795	COG4605	iron ion homeostasis
KY998_13805	COG0527	aspartate kinase activity
KY998_13810	COG0840	transmembrane signaling receptor activity
KY998_13825	COG0577	efflux transmembrane transporter activity
KY998_13835	COG0789	Transcriptional regulator
KY998_13840	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KY998_13850	COG0697	spore germination
KY998_13865	COG5434	Belongs to the glycosyl hydrolase 28 family
KY998_13870	COG3104	oligopeptide transport
KY998_13880	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
KY998_13890	COG1874	Beta-galactosidase
KY998_13895	COG0456	acetyltransferase
KY998_13895	COG1846	Transcriptional regulator
KY998_13900	COG2271	Major facilitator Superfamily
KY998_13905	COG4214	carbohydrate transport
KY998_13915	COG4213	ABC transporter substrate-binding protein
KY998_13925	COG2972	Histidine kinase
KY998_14000	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KY998_14005	COG0163	prenyltransferase activity
KY998_14015	COG0010	Belongs to the arginase family
KY998_14020	COG0833	amino acid
KY998_14025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KY998_14030	COG3829	transcription factor binding
KY998_14040	COG0765	amino acid transport
KY998_14065	COG2364	Membrane
KY998_14070	COG3708	Transcriptional regulator
KY998_14070	COG2207	Transcriptional regulator
KY998_14075	COG2819	hydrolase of the alpha beta superfamily
KY998_14085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KY998_14090	COG0697	spore germination
KY998_14095	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KY998_14105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KY998_14115	COG1177	transmembrane transport
KY998_14145	COG5444	nuclease activity
KY998_14160	COG3209	COG3209 Rhs family protein
KY998_14170	COG2723	6-phospho-beta-galactosidase activity
KY998_14175	COG1116	anion transmembrane transporter activity
KY998_14180	COG2249	NAD(P)H dehydrogenase (quinone) activity
KY998_14185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KY998_14190	COG0765	amino acid transport
KY998_14215	COG3458	cephalosporin-C deacetylase activity
KY998_14220	COG0701	Predicted permease
KY998_14225	COG3689	TIGRFAM TIGR03943 family protein
KY998_14235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KY998_14240	COG1012	belongs to the aldehyde dehydrogenase family
KY998_14245	COG0506	proline dehydrogenase activity
KY998_14250	COG3541	Predicted nucleotidyltransferase
KY998_14255	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KY998_14260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KY998_14265	COG1113	amino acid transport
KY998_14270	COG1280	lysine exporter protein (LysE YggA)
KY998_14275	COG1620	l-lactate permease
KY998_14280	COG0039	L-malate dehydrogenase activity
KY998_14285	COG2223	nitrite transmembrane transporter activity
KY998_14295	COG0785	Cytochrome C biogenesis protein
KY998_14300	COG3853	Toxic anion resistance protein (TelA)
KY998_14320	COG0861	Integral membrane protein TerC family
KY998_14325	COG2310	stress, protein
KY998_14330	COG2310	stress, protein
KY998_14335	COG2310	stress, protein
KY998_14355	COG1309	transcriptional regulator
KY998_14360	COG1131	(ABC) transporter
KY998_14370	COG3883	PFAM NLP P60 protein
KY998_14370	COG0791	NLP P60 protein
KY998_14380	COG3773	Cell wall hydrolase
KY998_14390	COG1595	DNA-templated transcription, initiation
KY998_14400	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_14405	COG3591	Belongs to the peptidase S1B family
KY998_14420	COG3394	polysaccharide catabolic process
KY998_14425	COG2188	Transcriptional regulator
KY998_14430	COG1486	melibiose metabolic process
KY998_14435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KY998_14440	COG1447	Phosphotransferase system cellobiose-specific component IIA
KY998_14445	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KY998_14450	COG0277	FAD linked oxidase domain protein
KY998_14455	COG0247	lactate metabolic process
KY998_14465	COG2261	transglycosylase associated protein
KY998_14470	COG1164	Oligoendopeptidase f
KY998_14480	COG0456	acetyltransferase
KY998_14485	COG0252	asparaginase activity
KY998_14510	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_14515	COG1942	4-Oxalocrotonate Tautomerase
KY998_14550	COG1405	negative regulation of cell septum assembly
KY998_14550	COG3012	SEC-C Motif Domain Protein
KY998_14560	COG0697	spore germination
KY998_14585	COG0789	Transcriptional regulator
KY998_14605	COG0318	PFAM AMP-dependent synthetase and ligase
KY998_14610	COG1846	Transcriptional regulator
KY998_14640	COG1131	(ABC) transporter
KY998_14645	COG2205	protein histidine kinase activity
KY998_14650	COG0745	RESPONSE REGULATOR receiver
KY998_14670	COG2721	sulfolactate sulfo-lyase activity
KY998_14675	COG2186	Transcriptional regulator
KY998_14680	COG4948	Mandelate Racemase Muconate Lactonizing
KY998_14685	COG2271	Major facilitator Superfamily
KY998_14695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KY998_14700	COG0805	protein transport
KY998_14705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KY998_14710	COG3540	Alkaline phosphatase
KY998_14735	COG0784	Response regulator, receiver
KY998_14740	COG4191	Histidine kinase
KY998_14745	COG2066	Belongs to the glutaminase family
KY998_14750	COG1115	amino acid carrier protein
KY998_14755	COG2205	protein histidine kinase activity
KY998_14760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KY998_14760	COG4451	ribulose bisphosphate carboxylase, small
KY998_14785	COG2040	homocysteine
KY998_14790	COG0833	amino acid
KY998_14800	COG4257	antibiotic catabolic process
KY998_14815	COG0371	Dehydrogenase
KY998_14845	COG1917	Cupin 2, conserved barrel domain protein
KY998_14845	COG2207	Transcriptional regulator
KY998_14850	COG0697	spore germination
KY998_14860	COG3409	Peptidoglycan-binding domain 1 protein
KY998_14870	COG4682	membrane
KY998_14875	COG1283	sodium-dependent phosphate transmembrane transporter activity
KY998_14895	COG0730	response to heat
KY998_14900	COG1802	Transcriptional regulator
KY998_14910	COG0076	glutamate decarboxylase activity
KY998_14915	COG2226	methyltransferase
KY998_14925	COG1331	Highly conserved protein containing a thioredoxin domain
KY998_14945	COG2211	Major facilitator Superfamily
KY998_14965	COG1011	Hydrolase
KY998_14985	COG2312	Erythromycin esterase
KY998_14995	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KY998_15000	COG1132	(ABC) transporter
KY998_15010	COG2814	Major facilitator Superfamily
KY998_15015	COG0640	Transcriptional regulator
KY998_15025	COG0789	Transcriptional regulator
KY998_15035	COG1725	Transcriptional regulator
KY998_15055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KY998_15060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KY998_15065	COG4856	YbbR-like protein
KY998_15070	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KY998_15075	COG5662	AntiSigma factor
KY998_15080	COG1595	DNA-templated transcription, initiation
KY998_15115	COG1683	Conserved Protein
KY998_15120	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KY998_15125	COG1737	Transcriptional regulator
KY998_15135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KY998_15140	COG1472	Belongs to the glycosyl hydrolase 3 family
KY998_15145	COG3876	Protein conserved in bacteria
KY998_15160	COG0385	Bile acid
KY998_15200	COG0726	polysaccharide deacetylase
KY998_15205	COG2194	sulfuric ester hydrolase activity
KY998_15215	COG0489	protein tyrosine kinase activity
KY998_15220	COG0860	N-Acetylmuramoyl-L-alanine amidase
KY998_15245	COG3290	protein histidine kinase activity
KY998_15315	COG1131	(ABC) transporter
KY998_15335	COG2318	DinB family
KY998_15355	COG0582	viral genome integration into host DNA
KY998_15360	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KY998_15365	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KY998_15370	COG0101	tRNA pseudouridine synthase activity
KY998_15375	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KY998_15380	COG1122	ATPase activity
KY998_15390	COG0203	ribosomal protein L17
KY998_15395	COG0202	RNA polymerase activity
KY998_15400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KY998_15405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KY998_15410	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KY998_15415	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KY998_15420	COG2163	COG2163 Ribosomal protein L14E L6E L27E
KY998_15425	COG0024	Methionine aminopeptidase
KY998_15430	COG0563	adenylate kinase activity
KY998_15435	COG0201	protein transport
KY998_15440	COG0200	Binds to the 23S rRNA
KY998_15445	COG1841	ribosomal large subunit assembly
KY998_15450	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KY998_15455	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KY998_15460	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KY998_15465	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KY998_15470	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KY998_15475	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KY998_15480	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KY998_15485	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KY998_15490	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KY998_15495	COG0255	Belongs to the universal ribosomal protein uL29 family
KY998_15500	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KY998_15505	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KY998_15510	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KY998_15515	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KY998_15525	COG0089	rRNA binding
KY998_15530	COG0088	Forms part of the polypeptide exit tunnel
KY998_15535	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KY998_15545	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KY998_15550	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KY998_15555	COG0049	tRNA binding
KY998_15560	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KY998_15565	COG1358	cellular component organization or biogenesis
KY998_15570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KY998_15575	COG0085	RNA polymerase activity
KY998_15580	COG2813	Specifically methylates the guanine in position
KY998_15585	COG0222	ribosome binding
KY998_15590	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KY998_15595	COG0081	regulation of translation
KY998_15600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KY998_15605	COG0250	Participates in transcription elongation, termination and antitermination
KY998_15625	COG3688	RNA-binding protein containing a PIN domain
KY998_15630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KY998_15640	COG0215	cysteine-tRNA ligase activity
KY998_15645	COG1045	serine acetyltransferase
KY998_15650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KY998_15655	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KY998_15660	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KY998_15665	COG4956	integral membrane protein (PIN domain superfamily)
KY998_15670	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KY998_15675	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KY998_15680	COG0542	response to heat
KY998_15685	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KY998_15690	COG3880	PFAM UvrB UvrC protein
KY998_15695	COG4463	regulation of RNA biosynthetic process
KY998_15775	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KY998_15780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KY998_15785	COG1396	sequence-specific DNA binding
KY998_15790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KY998_15795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KY998_15800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KY998_15805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KY998_15810	COG0512	Glutamine amidotransferase of anthranilate synthase
KY998_15815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KY998_15825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KY998_15830	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KY998_15835	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KY998_15840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KY998_15845	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KY998_15850	COG0037	tRNA processing
KY998_15855	COG0515	serine threonine protein kinase
KY998_15860	COG2304	oxidoreductase activity
KY998_15865	COG2208	phosphoserine phosphatase activity
KY998_15880	COG1098	S1 RNA binding domain
KY998_15885	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KY998_15905	COG3956	TIGRFAM MazG family protein
KY998_15910	COG2244	polysaccharide biosynthetic process
KY998_15915	COG2002	toxin-antitoxin pair type II binding
KY998_15920	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KY998_15930	COG0193	aminoacyl-tRNA hydrolase activity
KY998_15935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KY998_15940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KY998_15945	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KY998_15950	COG2088	sporulation resulting in formation of a cellular spore
KY998_15955	COG0251	oxidation-reduction process
KY998_15960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KY998_15965	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KY998_15975	COG4466	Protein conserved in bacteria
KY998_15985	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KY998_15990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KY998_15995	COG3584	3D domain protein
KY998_15995	COG3583	domain protein
KY998_16000	COG0084	hydrolase, TatD family'
KY998_16005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KY998_16005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KY998_16010	COG2002	toxin-antitoxin pair type II binding
KY998_16015	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KY998_16020	COG2827	Endonuclease containing a URI domain
KY998_16025	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KY998_16030	COG4467	Involved in initiation control of chromosome replication
KY998_16035	COG1774	PSP1 C-terminal conserved region
KY998_16045	COG1728	Protein conserved in bacteria
KY998_16050	COG3870	Protein conserved in bacteria
KY998_16055	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KY998_16060	COG1982	Orn Lys Arg decarboxylase major
KY998_16065	COG3853	Toxic anion resistance protein (TelA)
KY998_16070	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KY998_16115	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KY998_16120	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KY998_16125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KY998_16135	COG0590	tRNA wobble adenosine to inosine editing
KY998_16140	COG1335	isochorismatase
KY998_16145	COG1388	LysM domain
KY998_16145	COG3858	chitin binding
KY998_16150	COG1428	Deoxynucleoside kinase
KY998_16155	COG1428	Deoxynucleoside kinase
KY998_16170	COG3835	regulator
KY998_16175	COG2610	gluconate transmembrane transporter activity
KY998_16180	COG1929	Belongs to the glycerate kinase type-1 family
KY998_16185	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KY998_16190	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KY998_16195	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KY998_16200	COG1686	Belongs to the peptidase S11 family
KY998_16205	COG0517	IMP dehydrogenase activity
KY998_16205	COG0516	GMP reductase activity
KY998_16255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KY998_16260	COG2501	S4 domain
KY998_16265	COG0592	DNA-directed DNA polymerase activity
KY998_16270	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KY998_16280	COG0594	ribonuclease P activity
KY998_16285	COG0706	membrane insertase activity
KY998_16290	COG1847	R3H domain protein
KY998_16295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KY998_16300	COG0445	tRNA wobble uridine modification
KY998_16305	COG0357	Ribosomal RNA small subunit methyltransferase G
KY998_16310	COG1475	DNA binding
KY998_16315	COG1595	DNA-templated transcription, initiation
KY998_16320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KY998_16325	COG1192	Involved in chromosome partitioning
KY998_16330	COG1475	DNA binding
KY998_16340	COG3949	Membrane
KY998_16345	COG4481	Protein conserved in bacteria
KY998_16350	COG0012	GTP binding
KY998_16355	COG0360	Binds together with S18 to 16S ribosomal RNA
KY998_16360	COG0629	single-stranded DNA binding
KY998_16365	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KY998_16370	COG2271	Major facilitator Superfamily
KY998_16375	COG0659	secondary active sulfate transmembrane transporter activity
KY998_16380	COG0589	response to stress
KY998_16385	COG5577	PFAM Coat F domain
KY998_16395	COG4241	membrane
KY998_16400	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KY998_16405	COG0359	binds to the 23S rRNA
KY998_16410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KY998_16410	COG1263	PTS System
KY998_16415	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KY998_16420	COG2188	Transcriptional regulator
KY998_16425	COG0363	glucosamine-6-phosphate deaminase activity
KY998_16430	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KY998_16435	COG2807	transmembrane transport
KY998_16440	COG3093	addiction module antidote protein HigA
KY998_16455	COG0305	Participates in initiation and elongation during chromosome replication
KY998_16465	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KY998_16470	COG1051	belongs to the nudix hydrolase family
KY998_16495	COG0745	RESPONSE REGULATOR receiver
KY998_16500	COG5002	protein histidine kinase activity
KY998_16505	COG4863	YycH protein
KY998_16510	COG4853	Protein conserved in bacteria
KY998_16515	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KY998_16520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KY998_16535	COG0456	acetyltransferase
KY998_16550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KY998_16570	COG2197	response regulator
KY998_16580	COG0842	Transport permease protein
KY998_16585	COG1131	(ABC) transporter
KY998_16600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KY998_16605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KY998_16620	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
KY998_16645	COG3634	alkyl hydroperoxide reductase activity
KY998_16650	COG0450	alkyl hydroperoxide reductase
KY998_16655	COG1012	belongs to the aldehyde dehydrogenase family
KY998_16655	COG1454	alcohol dehydrogenase
KY998_16685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KY998_16700	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KY998_16705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KY998_16710	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KY998_16720	COG2182	Extracellular solute-binding protein
KY998_16725	COG1175	transmembrane transport
KY998_16730	COG3833	ABC-type maltose transport systems, permease component
KY998_16735	COG1874	Beta-galactosidase
KY998_16740	COG3867	Arabinogalactan endo-beta-1,4-galactanase
KY998_16750	COG1115	amino acid carrier protein
KY998_16755	COG5278	phosphoserine phosphatase activity
KY998_16755	COG0840	transmembrane signaling receptor activity
KY998_16765	COG0745	RESPONSE REGULATOR receiver
KY998_16770	COG2205	protein histidine kinase activity
KY998_16775	COG1136	(ABC) transporter
KY998_16785	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KY998_16815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KY998_16840	COG0488	(ABC) transporter
KY998_16845	COG0326	Molecular chaperone. Has ATPase activity
KY998_16850	COG2271	Major facilitator Superfamily
KY998_16855	COG0584	glycerophosphoryl diester phosphodiesterase
KY998_16860	COG0667	Aldo Keto reductase
KY998_16865	COG1349	DNA-binding transcription factor activity
KY998_16870	COG1012	belongs to the aldehyde dehydrogenase family
KY998_16875	COG3718	enzyme involved in inositol metabolism
KY998_16880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KY998_16885	COG3962	Belongs to the TPP enzyme family
KY998_16890	COG1082	Xylose isomerase domain protein TIM barrel
KY998_16895	COG2814	Major facilitator Superfamily
KY998_16900	COG0673	inositol 2-dehydrogenase activity
KY998_16905	COG1082	Xylose isomerase domain protein TIM barrel
KY998_16910	COG1082	Xylose isomerase domain protein TIM barrel
KY998_16915	COG0191	fructose-bisphosphate aldolase activity
KY998_16940	COG3977	Valine--pyruvate aminotransferase
KY998_16950	COG1215	transferase activity, transferring glycosyl groups
KY998_16955	COG5298	Protein conserved in bacteria
KY998_16960	COG3706	GGDEF domain
KY998_16965	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KY998_16975	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KY998_16985	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KY998_17010	COG0513	Belongs to the DEAD box helicase family
KY998_17015	COG3507	Belongs to the glycosyl hydrolase 43 family
KY998_17020	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KY998_17030	COG1263	PTS System
KY998_17030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KY998_17030	COG2190	(PTS) system
KY998_17035	COG2723	6-phospho-beta-galactosidase activity
KY998_17040	COG0745	RESPONSE REGULATOR receiver
KY998_17045	COG2205	protein histidine kinase activity
KY998_17050	COG1136	(ABC) transporter
KY998_17055	COG0577	efflux transmembrane transporter activity
KY998_17060	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KY998_17070	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KY998_17075	COG2224	Isocitrate lyase
KY998_17090	COG4721	ABC-type cobalt transport system, permease component
KY998_17100	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KY998_17105	COG3711	transcriptional antiterminator
KY998_17110	COG1263	PTS System
KY998_17110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KY998_17110	COG2190	(PTS) system
KY998_17115	COG2723	6-phospho-beta-galactosidase activity
KY998_17125	COG0693	protein deglycase activity
KY998_17125	COG0753	catalase activity
KY998_17130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KY998_17155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KY998_17160	COG0463	Glycosyl transferase, family 2
KY998_17170	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KY998_17185	COG1609	Transcriptional regulator
KY998_17195	COG1175	transmembrane transport
KY998_17200	COG0395	ABC-type sugar transport system, permease component
KY998_17205	COG2223	nitrite transmembrane transporter activity
KY998_17215	COG2195	Cleaves the N-terminal amino acid of tripeptides
KY998_17225	COG1595	DNA-templated transcription, initiation
KY998_17235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KY998_17240	COG2723	6-phospho-beta-galactosidase activity
KY998_17250	COG0549	Belongs to the carbamate kinase family
KY998_17260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KY998_17265	COG2235	arginine
KY998_17275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KY998_17300	COG0584	glycerophosphoryl diester phosphodiesterase
KY998_17305	COG3493	citrate carrier protein
KY998_17310	COG1215	transferase activity, transferring glycosyl groups
KY998_17330	COG0726	polysaccharide deacetylase
KY998_17345	COG2706	6-phosphogluconolactonase activity
KY998_17350	COG1396	sequence-specific DNA binding
KY998_17355	COG0252	asparaginase activity
KY998_17360	COG1027	Aspartate ammonia-lyase
KY998_17365	COG1757	Na H antiporter
KY998_17370	COG0281	malic enzyme
KY998_17380	COG2116	formate transmembrane transporter activity
KY998_17385	COG1271	oxidase subunit
KY998_17390	COG1294	oxidase, subunit
KY998_17405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KY998_17415	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KY998_17420	COG0735	belongs to the Fur family
KY998_17425	COG0753	catalase activity
KY998_17440	COG2814	Major facilitator Superfamily
KY998_17445	COG1595	DNA-templated transcription, initiation
KY998_17470	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KY998_17475	COG2814	Major facilitator Superfamily
KY998_17490	COG2755	lipolytic protein G-D-S-L family
KY998_17510	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KY998_17515	COG2079	MmgE PrpD family protein
KY998_17520	COG0372	Belongs to the citrate synthase family
KY998_17530	COG2094	Belongs to the DNA glycosylase MPG family
KY998_17535	COG3711	transcriptional antiterminator
KY998_17535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KY998_17540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KY998_17545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KY998_17550	COG1447	Phosphotransferase system cellobiose-specific component IIA
KY998_17555	COG1486	melibiose metabolic process
KY998_17560	COG2814	Major facilitator Superfamily
KY998_17565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KY998_17570	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KY998_17575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KY998_17580	COG1696	Membrane protein involved in D-alanine export
KY998_17585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KY998_17600	COG2357	RelA SpoT domain protein
KY998_17635	COG0800	Aldolase
KY998_17640	COG4948	Mandelate Racemase Muconate Lactonizing
KY998_17645	COG2271	Major facilitator Superfamily
KY998_17650	COG5522	Integral membrane protein (intg_mem_TP0381)
KY998_17655	COG2409	Drug exporters of the RND superfamily
KY998_17660	COG2197	response regulator
KY998_17665	COG4585	Histidine kinase
KY998_17675	COG1442	glycosyl transferase family 8
KY998_17680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KY998_17685	COG0346	lactoylglutathione lyase activity
KY998_17690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KY998_17695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KY998_17700	COG1346	cytolysis
KY998_17705	COG1380	Effector of murein hydrolase LrgA
KY998_17725	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KY998_17730	COG0352	thiamine-phosphate diphosphorylase activity
KY998_17735	COG1940	carbohydrate kinase activity
KY998_17740	COG2115	Belongs to the xylose isomerase family
KY998_17745	COG1070	Carbohydrate kinase
KY998_17750	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KY998_17755	COG3162	membrane
KY998_17760	COG0655	NAD(P)H dehydrogenase (quinone) activity
KY998_17770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KY998_17775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KY998_17780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KY998_17790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KY998_17825	COG0456	acetyltransferase
KY998_17845	COG3314	Sporulation integral membrane protein YlbJ
KY998_17850	COG0772	Belongs to the SEDS family
KY998_17855	COG0772	Belongs to the SEDS family
KY998_17860	COG1473	amidohydrolase
KY998_17865	COG0778	Nitroreductase
KY998_17875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KY998_17885	COG1404	Belongs to the peptidase S8 family
KY998_17895	COG3711	transcriptional antiterminator
KY998_17900	COG1263	PTS System
KY998_17900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KY998_17915	COG0351	phosphomethylpyrimidine kinase
KY998_17920	COG1216	Glycosyl transferase, family 2
KY998_17925	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KY998_17940	COG2233	PERMEase
KY998_17945	COG2363	Small membrane protein
KY998_17960	COG1131	(ABC) transporter
KY998_17980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KY998_17990	COG3253	May function as heme-dependent peroxidase
KY998_17995	COG0280	phosphate acetyltransferase
KY998_18005	COG1414	Transcriptional regulator
KY998_18030	COG2814	Major facilitator Superfamily
KY998_18055	COG4844	belongs to the
KY998_18060	COG1078	dGTPase activity
KY998_18065	COG3465	dGTPase activity
KY998_18075	COG1942	4-Oxalocrotonate Tautomerase
KY998_18080	COG1994	Peptidase M50
KY998_18095	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KY998_18100	COG0010	Belongs to the arginase family
KY998_18105	COG4506	Protein conserved in bacteria
KY998_18110	COG0018	arginyl-trna synthetase
KY998_18125	COG0247	lactate metabolic process
KY998_18125	COG2181	nitrate reductase activity
KY998_18130	COG0183	Belongs to the thiolase family
KY998_18155	COG3343	RNA polymerase activity
KY998_18160	COG0504	CTP synthase activity
KY998_18165	COG4821	SIS domain
KY998_18170	COG2204	response regulator
KY998_18175	COG0191	fructose-bisphosphate aldolase activity
KY998_18180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KY998_18185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KY998_18190	COG1494	fructose-1,6-bisphosphatase
KY998_18195	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KY998_18200	COG0254	rRNA binding
KY998_18205	COG1435	thymidine kinase activity
KY998_18210	COG0281	malic enzyme
KY998_18215	COG0679	Auxin Efflux Carrier
KY998_18220	COG0789	Transcriptional regulator
KY998_18225	COG0346	lactoylglutathione lyase activity
KY998_18230	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KY998_18235	COG2890	protein-(glutamine-N5) methyltransferase activity
KY998_18240	COG1609	Transcriptional regulator
KY998_18245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KY998_18250	COG0561	phosphatase activity
KY998_18255	COG0673	inositol 2-dehydrogenase activity
KY998_18260	COG0738	Major facilitator superfamily
KY998_18270	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KY998_18275	COG0009	L-threonylcarbamoyladenylate synthase
KY998_18280	COG1971	Probably functions as a manganese efflux pump
KY998_18285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KY998_18290	COG0698	ribose 5-phosphate isomerase
KY998_18295	COG4475	Protein of unknown function (DUF436)
KY998_18300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KY998_18305	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KY998_18325	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KY998_18330	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KY998_18335	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KY998_18340	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KY998_18345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KY998_18350	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KY998_18355	COG4836	Membrane
KY998_18365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KY998_18370	COG2385	sporulation resulting in formation of a cellular spore
KY998_18375	COG2304	oxidoreductase activity
KY998_18380	COG2304	oxidoreductase activity
KY998_18390	COG2223	nitrite transmembrane transporter activity
KY998_18400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KY998_18405	COG1994	Peptidase M50
KY998_18415	COG1959	2 iron, 2 sulfur cluster binding
KY998_18425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KY998_18440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KY998_18445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KY998_18450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KY998_18455	COG2819	hydrolase of the alpha beta superfamily
KY998_18460	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_18465	COG1169	isochorismate synthase
KY998_18470	COG1021	2,3-dihydroxybenzoate-AMP ligase
KY998_18475	COG1535	isochorismatase
KY998_18475	COG3433	isochorismatase activity
KY998_18485	COG3251	PFAM MbtH domain protein
KY998_18490	COG0477	Major facilitator Superfamily
KY998_18495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KY998_18505	COG1247	-acetyltransferase
KY998_18510	COG0739	heme binding
KY998_18520	COG0740	serine-type endopeptidase activity
KY998_18525	COG0347	Belongs to the P(II) protein family
KY998_18530	COG0004	ammonium transporteR
KY998_18540	COG0598	Magnesium transport protein CorA
KY998_18545	COG0517	IMP dehydrogenase activity
KY998_18560	COG3361	conserved protein (COG2071)
KY998_18565	COG3546	catalase activity
KY998_18570	COG1227	inorganic diphosphatase activity
KY998_18575	COG0671	phosphoesterase, PA-phosphatase related
KY998_18580	COG2814	Major facilitator Superfamily
KY998_18585	COG1846	Transcriptional regulator
KY998_18590	COG1609	Transcriptional regulator
KY998_18595	COG1077	Cell shape determining protein MreB Mrl
KY998_18600	COG4786	Flagellar basal body rod
KY998_18605	COG4786	Flagellar basal body rod
KY998_18610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KY998_18615	COG1970	mechanosensitive ion channel activity
KY998_18630	COG0629	single-stranded DNA binding
KY998_18660	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_18670	COG1349	DNA-binding transcription factor activity
KY998_18675	COG0561	phosphatase activity
KY998_18695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KY998_18700	COG3878	Protein conserved in bacteria
KY998_18705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KY998_18710	COG4715	Zinc finger, swim domain protein
KY998_18720	COG3944	biosynthesis protein
KY998_18725	COG4464	protein tyrosine phosphatase activity
KY998_18730	COG2059	Chromate
KY998_18735	COG2059	Chromate
KY998_18740	COG1522	sequence-specific DNA binding
KY998_18745	COG0405	Gamma-glutamyltransferase
KY998_18760	COG3527	Alpha-acetolactate decarboxylase
KY998_18765	COG2226	methyltransferase
KY998_18770	COG0583	DNA-binding transcription factor activity
KY998_18775	COG1879	ABC-type sugar transport system periplasmic component
KY998_18780	COG1172	Belongs to the binding-protein-dependent transport system permease family
KY998_18790	COG1869	D-ribose catabolic process
KY998_18795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KY998_18800	COG1609	Transcriptional regulator
KY998_18805	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KY998_18815	COG2843	Capsule synthesis protein
KY998_18825	COG0791	NLP P60 protein
KY998_18830	COG0561	phosphatase activity
KY998_18835	COG1316	TRANSCRIPTIONal
KY998_18840	COG2814	Major facilitator Superfamily
KY998_18850	COG1063	alcohol dehydrogenase
KY998_18855	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_18860	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KY998_18865	COG1609	Transcriptional regulator
KY998_18870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KY998_18900	COG4193	domain, Protein
KY998_18915	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KY998_18920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KY998_18940	COG4193	domain, Protein
KY998_18950	COG1682	transport, permease protein
KY998_18955	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KY998_18955	COG0463	Glycosyl transferase, family 2
KY998_18960	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KY998_18965	COG0438	transferase activity, transferring glycosyl groups
KY998_18970	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KY998_18975	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KY998_18980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KY998_18990	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KY998_18995	COG1316	TRANSCRIPTIONal
KY998_19005	COG0860	N-Acetylmuramoyl-L-alanine amidase
KY998_19005	COG2247	cell wall binding repeat
KY998_19015	COG2244	polysaccharide biosynthetic process
KY998_19020	COG0297	glycogen (starch) synthase activity
KY998_19020	COG0438	transferase activity, transferring glycosyl groups
KY998_19025	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KY998_19030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KY998_19035	COG3307	-O-antigen
KY998_19040	COG3206	protein involved in exopolysaccharide biosynthesis
KY998_19045	COG1215	transferase activity, transferring glycosyl groups
KY998_19050	COG0438	transferase activity, transferring glycosyl groups
KY998_19055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KY998_19065	COG1316	TRANSCRIPTIONal
KY998_19070	COG1739	Uncharacterized protein family UPF0029
KY998_19075	COG4585	Histidine kinase
KY998_19080	COG2197	response regulator
KY998_19085	COG1307	EDD domain protein, DegV family
KY998_19090	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KY998_19100	COG1040	competence protein
KY998_19110	COG2747	anti-sigma28 factor FlgM
KY998_19115	COG3418	PFAM FlgN family protein
KY998_19120	COG1256	bacterial-type flagellum assembly
KY998_19120	COG4786	Flagellar basal body rod
KY998_19125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KY998_19135	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KY998_19140	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KY998_19145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KY998_19155	COG1334	flagellar protein FlaG
KY998_19160	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KY998_19165	COG1516	flagellar protein fliS
KY998_19180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KY998_19185	COG0653	protein targeting
KY998_19190	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KY998_19195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KY998_19200	COG2010	Cytochrome c
KY998_19210	COG2177	Part of the ABC transporter FtsEX involved in
KY998_19215	COG0791	NLP P60 protein
KY998_19215	COG3883	PFAM NLP P60 protein
KY998_19220	COG0473	3-isopropylmalate dehydrogenase activity
KY998_19225	COG0793	Belongs to the peptidase S41A family
KY998_19225	COG3409	Peptidoglycan-binding domain 1 protein
KY998_19235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KY998_19245	COG4897	Protein conserved in bacteria
KY998_19250	COG0556	nucleotide-excision repair
KY998_19255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KY998_19275	COG3595	metallopeptidase activity
KY998_19280	COG1983	PspC domain protein
KY998_19285	COG1950	PFAM Membrane protein of
KY998_19290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KY998_19295	COG2814	Major facilitator Superfamily
KY998_19300	COG1846	Transcriptional regulator
KY998_19305	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KY998_19310	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KY998_19315	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KY998_19320	COG0546	phosphoglycolate phosphatase activity
KY998_19325	COG0110	maltose O-acetyltransferase activity
KY998_19330	COG5297	Belongs to the glycosyl hydrolase family 6
KY998_19335	COG4990	cell redox homeostasis
KY998_19340	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KY998_19345	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KY998_19350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KY998_19355	COG0131	Imidazoleglycerol-phosphate dehydratase
KY998_19360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KY998_19365	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KY998_19370	COG0107	imidazoleglycerol-phosphate synthase activity
KY998_19375	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KY998_19375	COG0140	phosphoribosyl-ATP diphosphatase activity
KY998_19380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KY998_19385	COG0457	Tetratricopeptide repeat
KY998_19390	COG0492	ferredoxin-NADP+ reductase activity
KY998_19395	COG1051	belongs to the nudix hydrolase family
KY998_19400	COG1660	Displays ATPase and GTPase activities
KY998_19405	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KY998_19410	COG1481	regulation of sporulation
KY998_19415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KY998_19420	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KY998_19425	COG2732	(Barnase) inhibitor
KY998_19435	COG0640	Transcriptional regulator
KY998_19440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KY998_19450	COG0288	reversible hydration of carbon dioxide
KY998_19455	COG0659	secondary active sulfate transmembrane transporter activity
KY998_19465	COG1694	Mazg nucleotide pyrophosphohydrolase
KY998_19470	COG1611	Belongs to the LOG family
KY998_19475	COG0740	serine-type endopeptidase activity
KY998_19495	COG1621	beta-fructofuranosidase activity
KY998_19500	COG1621	beta-fructofuranosidase activity
KY998_19505	COG1902	pentaerythritol trinitrate reductase activity
KY998_19510	COG1733	regulation of RNA biosynthetic process
KY998_19515	COG3829	transcription factor binding
KY998_19520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KY998_19525	COG1454	alcohol dehydrogenase
KY998_19535	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KY998_19545	COG2271	Major facilitator Superfamily
KY998_19550	COG2249	NAD(P)H dehydrogenase (quinone) activity
KY998_19560	COG1396	sequence-specific DNA binding
KY998_19565	COG3944	biosynthesis protein
KY998_19570	COG0489	protein tyrosine kinase activity
KY998_19575	COG1086	Polysaccharide biosynthesis protein
KY998_19580	COG0438	transferase activity, transferring glycosyl groups
KY998_19590	COG0438	transferase activity, transferring glycosyl groups
KY998_19600	COG1216	Glycosyl transferase, family 2
KY998_19605	COG5039	Polysaccharide pyruvyl transferase
KY998_19610	COG1216	Glycosyl transferase, family 2
KY998_19615	COG2244	polysaccharide biosynthetic process
KY998_19620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KY998_19625	COG0110	maltose O-acetyltransferase activity
KY998_19630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KY998_19635	COG5039	Polysaccharide pyruvyl transferase
KY998_19645	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KY998_19650	COG1620	l-lactate permease
KY998_19655	COG2186	Transcriptional regulator
KY998_19660	COG0247	lactate metabolic process
KY998_19665	COG1139	Iron-sulfur cluster binding protein
KY998_19670	COG1556	Lactate utilization protein
KY998_19690	COG1113	amino acid transport
KY998_19695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KY998_19700	COG2390	Transcriptional regulator
KY998_19705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KY998_19710	COG0126	phosphoglycerate kinase activity
KY998_19715	COG0149	triose-phosphate isomerase activity
KY998_19720	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KY998_19725	COG0148	phosphopyruvate hydratase activity
KY998_19730	COG0693	protein deglycase activity
KY998_19755	COG4640	response to antibiotic
KY998_19760	COG3064	Membrane
KY998_19765	COG2095	MarC family integral membrane protein
KY998_19770	COG1510	regulation of RNA biosynthetic process
KY998_19775	COG0517	IMP dehydrogenase activity
KY998_19775	COG1125	glycine betaine transport
KY998_19780	COG1174	glycine betaine transport
KY998_19785	COG1732	Glycine betaine
KY998_19790	COG1174	glycine betaine transport
KY998_19795	COG1396	sequence-specific DNA binding
KY998_19800	COG1396	sequence-specific DNA binding
KY998_19805	COG1476	TRANSCRIPTIONal
KY998_19810	COG2002	toxin-antitoxin pair type II binding
KY998_19815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KY998_19820	COG1647	Serine aminopeptidase, S33
KY998_19825	COG0557	exoribonuclease II activity
KY998_19830	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KY998_19850	COG5444	nuclease activity
KY998_19870	COG3507	Belongs to the glycosyl hydrolase 43 family
KY998_19875	COG5520	Belongs to the glycosyl hydrolase 30 family
KY998_19905	COG1191	sigma factor activity
KY998_19915	COG1054	Belongs to the UPF0176 family
KY998_19930	COG1396	sequence-specific DNA binding
KY998_19935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KY998_19940	COG0673	inositol 2-dehydrogenase activity
KY998_19960	COG2124	cytochrome p450
KY998_19970	COG2814	Major facilitator Superfamily
KY998_19975	COG2814	Major facilitator Superfamily
KY998_19980	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_19980	COG3347	Dehydrogenase
KY998_19990	COG4952	isomerase
KY998_19995	COG1070	Carbohydrate kinase
KY998_20005	COG0693	protein deglycase activity
KY998_20010	COG1937	Protein conserved in bacteria
KY998_20015	COG2608	mercury ion transmembrane transporter activity
KY998_20020	COG2217	Heavy metal translocating P-type atpase
KY998_20040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KY998_20045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KY998_20045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KY998_20045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KY998_20070	COG0803	Belongs to the bacterial solute-binding protein 9 family
KY998_20075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KY998_20080	COG1121	(ABC) transporter
KY998_20085	COG1472	Belongs to the glycosyl hydrolase 3 family
KY998_20090	COG1501	Belongs to the glycosyl hydrolase 31 family
KY998_20095	COG0395	ABC-type sugar transport system, permease component
KY998_20100	COG1175	transmembrane transport
KY998_20105	COG1653	transport
KY998_20110	COG2217	Heavy metal translocating P-type atpase
KY998_20115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KY998_20120	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KY998_20125	COG0456	acetyltransferase
KY998_20130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KY998_20130	COG0456	acetyltransferase
KY998_20135	COG2860	membrane
KY998_20140	COG3973	AAA domain
KY998_20145	COG0596	Alpha beta hydrolase
KY998_20155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KY998_20160	COG1940	carbohydrate kinase activity
KY998_20165	COG0656	L-ascorbic acid biosynthetic process
KY998_20170	COG2814	Major facilitator Superfamily
KY998_20175	COG1368	sulfuric ester hydrolase activity
KY998_20180	COG1988	membrane-bound metal-dependent
KY998_20190	COG0531	amino acid
KY998_20200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KY998_20205	COG1120	ATPase activity
KY998_20210	COG0745	RESPONSE REGULATOR receiver
KY998_20215	COG2205	protein histidine kinase activity
KY998_20220	COG1904	glucuronate isomerase
KY998_20225	COG2211	Major facilitator Superfamily
KY998_20230	COG1609	Transcriptional regulator
KY998_20235	COG0246	Mannitol dehydrogenase
KY998_20240	COG2721	sulfolactate sulfo-lyase activity
KY998_20250	COG0583	DNA-binding transcription factor activity
KY998_20255	COG2258	MOSC domain
KY998_20260	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_20265	COG1802	Transcriptional regulator
KY998_20270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KY998_20280	COG1120	ATPase activity
KY998_20285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KY998_20290	COG1454	alcohol dehydrogenase
KY998_20310	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_20315	COG2096	Adenosyltransferase
KY998_20320	COG4677	pectinesterase activity
KY998_20325	COG4758	membrane
KY998_20330	COG1842	Phage shock protein A
KY998_20335	COG3595	metallopeptidase activity
KY998_20345	COG4585	Histidine kinase
KY998_20350	COG2197	response regulator
KY998_20365	COG0814	amino acid
KY998_20370	COG0697	spore germination
KY998_20380	COG0114	fumarate hydratase activity
KY998_20385	COG1309	transcriptional regulator
KY998_20395	COG2205	protein histidine kinase activity
KY998_20395	COG2770	Histidine kinase
KY998_20405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KY998_20410	COG0783	Belongs to the Dps family
KY998_20415	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_20420	COG1686	Belongs to the peptidase S11 family
KY998_20435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KY998_20445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KY998_20450	COG1120	ATPase activity
KY998_20465	COG5577	PFAM Coat F domain
KY998_20480	COG1250	3-hydroxyacyl-CoA dehydrogenase
KY998_20480	COG1024	Enoyl-CoA hydratase
KY998_20485	COG0183	Belongs to the thiolase family
KY998_20490	COG1960	acyl-CoA dehydrogenase activity
KY998_20495	COG1393	Belongs to the ArsC family
KY998_20500	COG0509	glycine decarboxylation via glycine cleavage system
KY998_20510	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KY998_20515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KY998_20525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KY998_20530	COG2011	ABC-type metal ion transport system permease component
KY998_20535	COG1464	Belongs to the NlpA lipoprotein family
KY998_20540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KY998_20550	COG0396	ATPase activity
KY998_20560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KY998_20565	COG0822	iron-sulfur transferase activity
KY998_20570	COG0719	Fe-S assembly protein
KY998_20580	COG0457	Tetratricopeptide repeat
KY998_20595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KY998_20605	COG2356	endonuclease I
KY998_20615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KY998_20620	COG1288	antiporter activity
KY998_20625	COG2814	Major facilitator Superfamily
KY998_20630	COG2508	Transcriptional regulator
KY998_20635	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KY998_20640	COG3226	Transcriptional regulator
KY998_20655	COG0730	response to heat
KY998_20665	COG3377	Domain of unknown function (DUF1805)
KY998_20675	COG0733	neurotransmitter:sodium symporter activity
KY998_20705	COG4470	Protein conserved in bacteria
KY998_20710	COG2445	Protein of unknown function DUF86
KY998_20715	COG0647	UMP catabolic process
KY998_20720	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KY998_20725	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KY998_20730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KY998_20735	COG0460	homoserine dehydrogenase
KY998_20740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KY998_20745	COG0083	homoserine kinase activity
KY998_20750	COG1506	peptidase
KY998_20750	COG0823	Involved in the tonB-independent uptake of proteins
KY998_20750	COG4946	Tricorn protease homolog
KY998_20760	COG4837	Protein of unknown function (DUF1462)
KY998_20770	COG3479	Phenolic acid decarboxylase
KY998_20775	COG0457	Tetratricopeptide repeat
KY998_20790	COG5646	InterPro IPR014922
KY998_20795	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KY998_20800	COG2323	membrane
KY998_20805	COG1252	NADH dehydrogenase
KY998_20810	COG4844	belongs to the
KY998_20815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KY998_20820	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KY998_20825	COG0316	Belongs to the HesB IscA family
KY998_20830	COG0456	acetyltransferase
KY998_20845	COG0492	ferredoxin-NADP+ reductase activity
KY998_20850	COG1252	NADH dehydrogenase
KY998_20865	COG3584	3D domain protein
KY998_20870	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KY998_20875	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KY998_20880	COG2056	Na+-H+ antiporter family
KY998_20885	COG1268	BioY protein
KY998_20890	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KY998_20900	COG0686	Belongs to the AlaDH PNT family
KY998_20905	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KY998_20905	COG2508	Transcriptional regulator
KY998_20910	COG1115	amino acid carrier protein
KY998_20915	COG4842	Belongs to the WXG100 family
KY998_20920	COG5417	Belongs to the EsaB family
KY998_20925	COG4499	WXG100 protein secretion system (Wss), protein YukC
KY998_20930	COG0433	COG0433 Predicted ATPase
KY998_20930	COG1674	ftsk spoiiie
KY998_20935	COG1511	domain protein
KY998_20955	COG1418	mRNA catabolic process
KY998_20970	COG1959	2 iron, 2 sulfur cluster binding
KY998_20975	COG0628	permease
KY998_20990	COG5506	Protein of unknown function (DUF1694)
KY998_20995	COG1335	isochorismatase
KY998_21000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KY998_21005	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KY998_21025	COG4585	Histidine kinase
KY998_21030	COG2197	response regulator
KY998_21035	COG2050	protein possibly involved in aromatic compounds catabolism
KY998_21040	COG1320	monovalent cation:proton antiporter activity
KY998_21045	COG2212	antiporter activity
KY998_21050	COG1863	multisubunit Na H antiporter MnhE subunit
KY998_21055	COG0651	ATP synthesis coupled electron transport
KY998_21060	COG1006	Multisubunit Na H antiporter MnhC subunit
KY998_21065	COG2111	Na H antiporter
KY998_21070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KY998_21070	COG2111	Na H antiporter
KY998_21080	COG3493	citrate carrier protein
KY998_21085	COG0688	phosphatidylethanolamine metabolic process
KY998_21090	COG0586	Pfam SNARE associated Golgi protein
KY998_21095	COG1183	phosphatidylcholine synthase activity
KY998_21100	COG1079	Belongs to the binding-protein-dependent transport system permease family
KY998_21120	COG3011	Protein conserved in bacteria
KY998_21130	COG2814	Major facilitator Superfamily
KY998_21135	COG5018	Exonuclease
KY998_21150	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KY998_21165	COG2267	carboxylic ester hydrolase activity
KY998_21170	COG1522	sequence-specific DNA binding
KY998_21185	COG2155	Conserved Protein
KY998_21190	COG1979	alcohol dehydrogenase
KY998_21195	COG0166	Belongs to the GPI family
KY998_21205	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KY998_21210	COG2323	membrane
KY998_21220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KY998_21235	COG2738	Putative neutral zinc metallopeptidase
KY998_21240	COG1253	flavin adenine dinucleotide binding
KY998_21245	COG5297	Belongs to the glycosyl hydrolase family 6
KY998_21260	COG0366	Alpha amylase catalytic
KY998_21265	COG0432	Pfam Uncharacterised protein family UPF0047
KY998_21270	COG2070	2-Nitropropane dioxygenase
KY998_21280	COG0840	transmembrane signaling receptor activity
KY998_21285	COG0840	transmembrane signaling receptor activity
KY998_21295	COG0693	protein deglycase activity
KY998_21300	COG0673	inositol 2-dehydrogenase activity
KY998_21305	COG0628	permease
KY998_21310	COG1968	undecaprenyl-diphosphatase activity
KY998_21315	COG1408	metallophosphoesterase
KY998_21320	COG0726	polysaccharide deacetylase
KY998_21325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KY998_21340	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
KY998_21400	COG1397	ADP-ribosylglycohydrolase
KY998_21410	COG2140	Oxalate decarboxylase
KY998_21415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KY998_21420	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KY998_21430	COG1510	regulation of RNA biosynthetic process
KY998_21435	COG1012	belongs to the aldehyde dehydrogenase family
KY998_21440	COG1454	alcohol dehydrogenase
KY998_21450	COG2318	DinB family
KY998_21465	COG0569	domain protein
KY998_21470	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KY998_21475	COG0457	Tetratricopeptide repeat
KY998_21490	COG3764	Sortase (surface protein transpeptidase)
KY998_21495	COG3859	Proton-coupled thiamine transporter YuaJ
KY998_21500	COG1609	Transcriptional regulator
KY998_21630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KY998_21635	COG0297	glycogen (starch) synthase activity
KY998_21640	COG0058	SHG alpha-glucan phosphorylase activity
KY998_21650	COG1575	Belongs to the MenA family. Type 1 subfamily
KY998_21665	COG0596	Alpha beta hydrolase
KY998_21670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KY998_21680	COG4948	Mandelate Racemase Muconate Lactonizing
KY998_21695	COG1294	oxidase, subunit
KY998_21700	COG1271	oxidase subunit
KY998_21705	COG0254	rRNA binding
KY998_21710	COG0803	Belongs to the bacterial solute-binding protein 9 family
KY998_21720	COG0288	reversible hydration of carbon dioxide
KY998_21725	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KY998_21730	COG1854	S-ribosylhomocysteine lyase activity
KY998_21745	COG0783	Belongs to the Dps family
KY998_21750	COG4824	toxin secretion phage lysis holin
KY998_21760	COG0494	nUDIX hydrolase
KY998_21780	COG1506	peptidase
KY998_21795	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KY998_21800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KY998_21805	COG0367	asparagine synthase
KY998_21810	COG0438	transferase activity, transferring glycosyl groups
KY998_21810	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KY998_21820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KY998_21825	COG2267	carboxylic ester hydrolase activity
KY998_21835	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KY998_21840	COG1242	4 iron, 4 sulfur cluster binding
KY998_21850	COG1725	Transcriptional regulator
KY998_21855	COG1131	(ABC) transporter
KY998_21870	COG0577	efflux transmembrane transporter activity
KY998_21875	COG2433	Pfam Transposase IS66
KY998_21880	COG1464	Belongs to the NlpA lipoprotein family
KY998_21885	COG2814	Major facilitator Superfamily
KY998_21900	COG0346	lactoylglutathione lyase activity
KY998_21905	COG0583	DNA-binding transcription factor activity
KY998_21915	COG1073	alpha beta
KY998_21920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KY998_21925	COG0395	ABC-type sugar transport system, permease component
KY998_21930	COG1653	transport
KY998_21935	COG2207	Transcriptional regulator
KY998_21940	COG4209	transmembrane transport
KY998_21945	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KY998_21950	COG1653	transport
KY998_21955	COG0673	inositol 2-dehydrogenase activity
KY998_21960	COG5578	integral membrane protein
KY998_21970	COG0457	Tetratricopeptide repeat
KY998_21975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KY998_21985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KY998_21990	COG2081	HI0933 family
KY998_21995	COG2244	polysaccharide biosynthetic process
KY998_22000	COG1187	pseudouridine synthase activity
KY998_22005	COG1349	DNA-binding transcription factor activity
KY998_22010	COG1131	(ABC) transporter
KY998_22015	COG4473	ABC transporter
KY998_22020	COG2252	PERMEase
KY998_22025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KY998_22040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KY998_22045	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KY998_22055	COG1597	lipid kinase activity
KY998_22060	COG1523	belongs to the glycosyl hydrolase 13 family
KY998_22065	COG0510	thiamine kinase activity
KY998_22075	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KY998_22080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KY998_22090	COG5584	Small secreted protein
KY998_22095	COG1363	Peptidase, m42
KY998_22105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KY998_22110	COG4848	Belongs to the UPF0354 family
KY998_22115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KY998_22125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KY998_22130	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KY998_22135	COG4980	gas vesicle protein
KY998_22140	COG3118	belongs to the thioredoxin family
KY998_22150	COG1605	Chorismate mutase
KY998_22150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KY998_22155	COG1609	Transcriptional regulator
KY998_22160	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KY998_22165	COG1360	Flagellar Motor Protein
KY998_22170	COG0123	including yeast histone deacetylase and acetoin utilization protein
KY998_22175	COG0517	IMP dehydrogenase activity
KY998_22180	COG0454	-acetyltransferase
KY998_22185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KY998_22205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KY998_22220	COG1309	transcriptional regulator
KY998_22225	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KY998_22230	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KY998_22235	COG1114	Component of the transport system for branched-chain amino acids
KY998_22240	COG1104	cysteine desulfurase activity
KY998_22245	COG0301	tRNA thio-modification
KY998_22255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KY998_22260	COG1846	Transcriptional regulator
KY998_22265	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KY998_22270	COG0616	signal peptide processing
KY998_22275	COG1714	RDD family
KY998_22285	COG3874	Sporulation protein YtfJ
KY998_22290	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KY998_22295	COG0827	DNA restriction-modification system
KY998_22300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KY998_22305	COG0521	Mo-molybdopterin cofactor biosynthetic process
KY998_22310	COG0137	argininosuccinate synthase activity
KY998_22315	COG0165	Argininosuccinate lyase
KY998_22325	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_22330	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KY998_22335	COG1695	Transcriptional regulator
KY998_22340	COG4109	DRTGG domain
KY998_22350	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KY998_22370	COG0587	DNA-directed DNA polymerase activity
KY998_22375	COG0281	malic enzyme
KY998_22380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KY998_22400	COG3030	protein affecting phage T7 exclusion by the F plasmid
KY998_22405	COG0628	permease
KY998_22410	COG2707	UPF0756 membrane protein
KY998_22420	COG2273	Hydrolase Family 16
KY998_22425	COG0372	Belongs to the citrate synthase family
KY998_22430	COG0538	isocitrate dehydrogenase activity
KY998_22435	COG0039	L-malate dehydrogenase activity
KY998_22445	COG5002	protein histidine kinase activity
KY998_22450	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KY998_22450	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KY998_22455	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KY998_22460	COG1971	Probably functions as a manganese efflux pump
KY998_22465	COG0237	dephospho-CoA kinase activity
KY998_22470	COG3866	Pectate lyase
KY998_22475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KY998_22480	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KY998_22490	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KY998_22495	COG3611	Membrane attachment protein
KY998_22500	COG1484	DNA-dependent DNA replication
KY998_22505	COG0398	Pfam SNARE associated Golgi protein
KY998_22515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KY998_22520	COG1011	Hydrolase
KY998_22535	COG3279	Response regulator of the LytR AlgR family
KY998_22550	COG1346	cytolysis
KY998_22555	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KY998_22560	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KY998_22565	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KY998_22570	COG3326	Membrane
KY998_22580	COG1363	Peptidase, m42
KY998_22585	COG3507	Belongs to the glycosyl hydrolase 43 family
KY998_22590	COG2160	L-arabinose isomerase activity
KY998_22595	COG1069	ribulokinase activity
KY998_22600	COG0235	Class ii aldolase
KY998_22605	COG0371	Dehydrogenase
KY998_22610	COG1653	transport
KY998_22615	COG1175	transmembrane transport
KY998_22620	COG0395	ABC-type sugar transport system, permease component
KY998_22660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KY998_22665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KY998_22670	COG0072	phenylalanine-tRNA ligase activity
KY998_22670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KY998_22685	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KY998_22690	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KY998_22700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KY998_22700	COG1796	DNA polymerase
KY998_22710	COG3766	membrane
KY998_22720	COG1309	transcriptional regulator
KY998_22725	COG1024	Enoyl-CoA hydratase
KY998_22730	COG2086	electron transfer activity
KY998_22735	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KY998_22740	COG3118	belongs to the thioredoxin family
KY998_22745	COG0322	excinuclease ABC activity
KY998_22755	COG1719	4-vinyl reductase, 4VR
KY998_22760	COG2009	succinate dehydrogenase
KY998_22765	COG1053	succinate dehydrogenase
KY998_22770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KY998_22775	COG0824	Thioesterase
KY998_22780	COG4221	oxidoreductase activity
KY998_22785	COG2197	response regulator
KY998_22790	COG1846	Transcriptional regulator
KY998_22795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KY998_22800	COG5401	PFAM Sporulation and spore germination
KY998_22805	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KY998_22810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KY998_22815	COG0622	Phosphoesterase
KY998_22835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KY998_22845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KY998_22850	COG0028	Belongs to the TPP enzyme family
KY998_22855	COG0440	acetolactate synthase activity
KY998_22860	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KY998_22865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KY998_22870	COG0473	3-isopropylmalate dehydrogenase activity
KY998_22875	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KY998_22880	COG0066	3-isopropylmalate dehydratase activity
KY998_22885	COG0457	Tetratricopeptide repeat
KY998_22885	COG1477	protein flavinylation
KY998_22890	COG0544	peptidyl-prolyl cis-trans isomerase activity
KY998_22895	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KY998_22905	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KY998_22910	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KY998_22920	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KY998_22925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KY998_22930	COG0181	hydroxymethylbilane synthase activity
KY998_22935	COG1587	Uroporphyrinogen-III synthase
KY998_22940	COG0113	porphobilinogen synthase activity
KY998_22945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KY998_22950	COG1388	LysM domain
KY998_22955	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KY998_22965	COG0525	valine-tRNA ligase activity
KY998_22970	COG0285	dihydrofolate synthase activity
KY998_22975	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KY998_22985	COG2801	Transposase and inactivated derivatives
KY998_22990	COG0424	maF-like protein
KY998_22995	COG2003	Belongs to the UPF0758 family
KY998_23000	COG1077	Cell shape determining protein MreB Mrl
KY998_23010	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KY998_23015	COG0850	regulation of cytokinetic process
KY998_23020	COG2894	cell division
KY998_23025	COG0640	Transcriptional regulator
KY998_23030	COG3832	glyoxalase III activity
KY998_23035	COG0739	heme binding
KY998_23040	COG1994	Peptidase M50
KY998_23045	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KY998_23050	COG2868	ribosomal protein
KY998_23055	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KY998_23060	COG3290	protein histidine kinase activity
KY998_23110	COG0747	negative chemotaxis
KY998_23130	COG0156	8-amino-7-oxononanoate synthase activity
KY998_23140	COG5444	nuclease activity
KY998_23150	COG3708	Transcriptional regulator
KY998_23165	COG0488	(ABC) transporter
KY998_23170	COG1121	(ABC) transporter
KY998_23175	COG0488	(ABC) transporter
KY998_23230	COG1609	Transcriptional regulator
KY998_23235	COG1609	Transcriptional regulator
KY998_23340	COG0739	heme binding
KY998_23340	COG0741	lytic transglycosylase activity
KY998_23340	COG1196	nuclear chromosome segregation
KY998_23350	COG0739	heme binding
KY998_23350	COG0741	lytic transglycosylase activity
KY998_23350	COG1196	nuclear chromosome segregation
KY998_23365	COG2814	Major facilitator Superfamily
KY998_23390	COG2755	lipolytic protein G-D-S-L family
KY998_23400	COG1063	alcohol dehydrogenase
KY998_23420	COG4565	transcriptional regulatory protein
KY998_23450	COG0420	3'-5' exonuclease activity
KY998_23470	COG0457	Tetratricopeptide repeat
KY998_23590	COG0457	Tetratricopeptide repeat
KY998_23595	COG0457	Tetratricopeptide repeat
KY998_23625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KY998_23625	COG2207	Transcriptional regulator
KY998_23630	COG2207	Transcriptional regulator
KY998_23630	COG4753	response regulator
KY998_23635	COG5444	nuclease activity
KY998_23700	COG2274	protein secretion by the type I secretion system
KY998_23715	COG4824	toxin secretion phage lysis holin
KY998_23735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KY998_23760	COG1960	acyl-CoA dehydrogenase activity
KY998_23765	COG1960	acyl-CoA dehydrogenase activity
KY998_23810	COG3829	transcription factor binding
KY998_23820	COG0395	ABC-type sugar transport system, permease component
KY998_23890	COG1331	Highly conserved protein containing a thioredoxin domain
KY998_23905	COG1027	Aspartate ammonia-lyase
KY998_23915	COG0697	spore germination
KY998_23950	COG5444	nuclease activity
KY998_23985	COG1115	amino acid carrier protein
KY998_23990	COG1024	Enoyl-CoA hydratase
KY998_23995	COG1028	Short-chain dehydrogenase reductase Sdr
KY998_24045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KY998_24050	COG2271	Major facilitator Superfamily
KY998_24060	COG0753	catalase activity
KY998_24065	COG0753	catalase activity
KY998_24070	COG0753	catalase activity
KY998_24075	COG1122	ATPase activity
KY998_24080	COG1122	ATPase activity
KY998_24090	COG1113	amino acid transport
KY998_24095	COG1113	amino acid transport
KY998_24100	COG1113	amino acid transport