locus-tag	class	description
NRZ52_00010	COG0735	belongs to the Fur family
NRZ52_00015	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NRZ52_00035	COG4555	ABC transporter
NRZ52_00045	COG0067	glutamate synthase
NRZ52_00045	COG0069	glutamate synthase activity
NRZ52_00045	COG0070	glutamate synthase
NRZ52_00050	COG4129	membrane
NRZ52_00055	COG1132	(ABC) transporter
NRZ52_00080	COG1194	a g-specific adenine glycosylase
NRZ52_00085	COG1988	membrane-bound metal-dependent
NRZ52_00115	COG1090	epimerase
NRZ52_00120	COG0402	S-adenosylhomocysteine deaminase activity
NRZ52_00140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRZ52_00155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NRZ52_00155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ52_00165	COG0463	Glycosyl transferase, family 2
NRZ52_00180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NRZ52_00185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ52_00185	COG1263	PTS System
NRZ52_00215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRZ52_00220	COG0833	amino acid
NRZ52_00230	COG3829	transcription factor binding
NRZ52_00250	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NRZ52_00270	COG0535	radical SAM domain protein
NRZ52_00280	COG0387	Pfam Sodium calcium exchanger
NRZ52_00285	COG3871	stress protein (general stress protein 26)
NRZ52_00300	COG0586	Pfam SNARE associated Golgi protein
NRZ52_00325	COG0697	spore germination
NRZ52_00330	COG2217	Heavy metal translocating P-type atpase
NRZ52_00335	COG1295	ribonuclease BN
NRZ52_00345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NRZ52_00360	COG3853	Toxic anion resistance protein (TelA)
NRZ52_00370	COG0861	Integral membrane protein TerC family
NRZ52_00375	COG2310	stress, protein
NRZ52_00380	COG2310	stress, protein
NRZ52_00385	COG2310	stress, protein
NRZ52_00415	COG2270	Major facilitator Superfamily
NRZ52_00465	COG0488	(ABC) transporter
NRZ52_00470	COG1116	anion transmembrane transporter activity
NRZ52_00480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ52_00525	COG1263	PTS System
NRZ52_00525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ52_00525	COG2190	(PTS) system
NRZ52_00530	COG0366	Alpha amylase catalytic
NRZ52_00535	COG0277	FAD linked oxidase domain protein
NRZ52_00540	COG0840	transmembrane signaling receptor activity
NRZ52_00545	COG0840	transmembrane signaling receptor activity
NRZ52_00555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ52_00560	COG0765	amino acid transport
NRZ52_00585	COG0723	plastoquinol--plastocyanin reductase activity
NRZ52_00585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ52_00590	COG2814	Major facilitator Superfamily
NRZ52_00600	COG3541	Predicted nucleotidyltransferase
NRZ52_00640	COG0166	Belongs to the GPI family
NRZ52_00655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ52_00660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ52_00665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ52_00685	COG0450	alkyl hydroperoxide reductase
NRZ52_00700	COG1473	amidohydrolase
NRZ52_00705	COG1757	Na H antiporter
NRZ52_00735	COG4807	Protein conserved in bacteria
NRZ52_00745	COG0028	Belongs to the TPP enzyme family
NRZ52_00755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRZ52_00760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRZ52_00765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ52_00775	COG2309	aminopeptidase activity
NRZ52_00780	COG2076	Multidrug Resistance protein
NRZ52_00785	COG1012	belongs to the aldehyde dehydrogenase family
NRZ52_00795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NRZ52_00800	COG0546	phosphoglycolate phosphatase activity
NRZ52_00805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NRZ52_00810	COG1597	lipid kinase activity
NRZ52_00830	COG4682	membrane
NRZ52_00835	COG1846	Transcriptional regulator
NRZ52_00840	COG0003	Pfam Anion-transporting ATPase
NRZ52_00855	COG1464	Belongs to the NlpA lipoprotein family
NRZ52_00860	COG2011	ABC-type metal ion transport system permease component
NRZ52_00870	COG1335	isochorismatase
NRZ52_00890	COG4851	CamS sex pheromone cAM373 precursor
NRZ52_00900	COG0210	DNA helicase
NRZ52_00925	COG0151	Belongs to the GarS family
NRZ52_00935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NRZ52_00945	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NRZ52_00960	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NRZ52_00970	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NRZ52_00975	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NRZ52_00980	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NRZ52_01005	COG0697	spore germination
NRZ52_01030	COG1215	transferase activity, transferring glycosyl groups
NRZ52_01050	COG2226	methyltransferase
NRZ52_01080	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NRZ52_01105	COG5002	protein histidine kinase activity
NRZ52_01115	COG2252	PERMEase
NRZ52_01145	COG1266	CAAX protease self-immunity
NRZ52_01160	COG0488	(ABC) transporter
NRZ52_01170	COG0456	acetyltransferase
NRZ52_01175	COG1214	PFAM Peptidase M22, glycoprotease
NRZ52_01180	COG0802	atpase or kinase
NRZ52_01275	COG2183	response to ionizing radiation
NRZ52_01280	COG2337	Toxic component of a toxin-antitoxin (TA) module
NRZ52_01285	COG0864	Transcriptional regulator
NRZ52_01290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRZ52_01295	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NRZ52_01305	COG0705	Rhomboid family
NRZ52_01310	COG4294	response to UV
NRZ52_01320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRZ52_01335	COG0531	amino acid
NRZ52_01345	COG0179	Fumarylacetoacetate (FAA) hydrolase
NRZ52_01350	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NRZ52_01380	COG0561	phosphatase activity
NRZ52_01385	COG4608	Belongs to the ABC transporter superfamily
NRZ52_01390	COG0444	Belongs to the ABC transporter superfamily
NRZ52_01395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ52_01400	COG0601	transmembrane transport
NRZ52_01405	COG0747	negative chemotaxis
NRZ52_01410	COG0747	negative chemotaxis
NRZ52_01420	COG0842	Transport permease protein
NRZ52_01425	COG0842	Transport permease protein
NRZ52_01425	COG1511	domain protein
NRZ52_01430	COG1131	(ABC) transporter
NRZ52_01435	COG2197	response regulator
NRZ52_01440	COG4585	Histidine kinase
NRZ52_01445	COG0488	(ABC) transporter
NRZ52_01470	COG5298	Protein conserved in bacteria
NRZ52_01480	COG0084	hydrolase, TatD family'
NRZ52_01490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ52_01500	COG1609	Transcriptional regulator
NRZ52_01510	COG0204	Acyl-transferase
NRZ52_01525	COG0697	spore germination
NRZ52_01540	COG1910	domain protein
NRZ52_01545	COG0725	ABC transporter, periplasmic molybdate-binding protein
NRZ52_01550	COG4149	molybdate abc transporter
NRZ52_01565	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRZ52_01570	COG0656	L-ascorbic acid biosynthetic process
NRZ52_01575	COG4166	transmembrane transport
NRZ52_01590	COG1309	transcriptional regulator
NRZ52_01600	COG2207	Transcriptional regulator
NRZ52_01610	COG4166	transmembrane transport
NRZ52_01615	COG4608	Belongs to the ABC transporter superfamily
NRZ52_01620	COG0444	Belongs to the ABC transporter superfamily
NRZ52_01625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ52_01630	COG0601	transmembrane transport
NRZ52_01645	COG2814	Major facilitator Superfamily
NRZ52_01655	COG2271	Major facilitator Superfamily
NRZ52_01660	COG0277	FAD linked oxidase domain protein
NRZ52_01670	COG0604	alcohol dehydrogenase
NRZ52_01675	COG1464	Belongs to the NlpA lipoprotein family
NRZ52_01685	COG2011	ABC-type metal ion transport system permease component
NRZ52_01690	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_01725	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NRZ52_01745	COG0596	Alpha beta hydrolase
NRZ52_01760	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_01770	COG1063	alcohol dehydrogenase
NRZ52_01820	COG4856	YbbR-like protein
NRZ52_01825	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NRZ52_01905	COG0726	polysaccharide deacetylase
NRZ52_01910	COG2194	sulfuric ester hydrolase activity
NRZ52_01920	COG0489	protein tyrosine kinase activity
NRZ52_01925	COG0860	N-Acetylmuramoyl-L-alanine amidase
NRZ52_01950	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NRZ52_01980	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NRZ52_01985	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NRZ52_01995	COG0024	Methionine aminopeptidase
NRZ52_02005	COG0201	protein transport
NRZ52_02065	COG0255	Belongs to the universal ribosomal protein uL29 family
NRZ52_02135	COG1358	cellular component organization or biogenesis
NRZ52_02150	COG2813	Specifically methylates the guanine in position
NRZ52_02170	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NRZ52_02175	COG0250	Participates in transcription elongation, termination and antitermination
NRZ52_02180	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRZ52_02195	COG3688	RNA-binding protein containing a PIN domain
NRZ52_02200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRZ52_02215	COG1045	serine acetyltransferase
NRZ52_02235	COG4956	integral membrane protein (PIN domain superfamily)
NRZ52_02245	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NRZ52_02250	COG0542	response to heat
NRZ52_02260	COG3880	PFAM UvrB UvrC protein
NRZ52_02310	COG0544	peptidyl-prolyl cis-trans isomerase activity
NRZ52_02350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRZ52_02355	COG1396	sequence-specific DNA binding
NRZ52_02360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NRZ52_02365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NRZ52_02370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NRZ52_02375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRZ52_02380	COG0512	Glutamine amidotransferase of anthranilate synthase
NRZ52_02385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NRZ52_02390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NRZ52_02405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NRZ52_02410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NRZ52_02420	COG2208	phosphoserine phosphatase activity
NRZ52_02435	COG1098	S1 RNA binding domain
NRZ52_02455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NRZ52_02460	COG3956	TIGRFAM MazG family protein
NRZ52_02465	COG2244	polysaccharide biosynthetic process
NRZ52_02470	COG2002	toxin-antitoxin pair type II binding
NRZ52_02475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NRZ52_02505	COG0251	oxidation-reduction process
NRZ52_02510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NRZ52_02525	COG4466	Protein conserved in bacteria
NRZ52_02540	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NRZ52_02545	COG0084	hydrolase, TatD family'
NRZ52_02550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ52_02550	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ52_02555	COG2002	toxin-antitoxin pair type II binding
NRZ52_02560	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NRZ52_02570	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NRZ52_02580	COG1774	PSP1 C-terminal conserved region
NRZ52_02585	COG0470	DNA polymerase III
NRZ52_02595	COG1982	Orn Lys Arg decarboxylase major
NRZ52_02650	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NRZ52_02660	COG0590	tRNA wobble adenosine to inosine editing
NRZ52_02665	COG1335	isochorismatase
NRZ52_02670	COG1428	Deoxynucleoside kinase
NRZ52_02675	COG1428	Deoxynucleoside kinase
NRZ52_02705	COG1686	Belongs to the peptidase S11 family
NRZ52_02710	COG0517	IMP dehydrogenase activity
NRZ52_02710	COG0516	GMP reductase activity
NRZ52_02745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NRZ52_02750	COG0187	DNA topoisomerase II activity
NRZ52_02760	COG2501	S4 domain
NRZ52_02765	COG0592	DNA-directed DNA polymerase activity
NRZ52_02775	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NRZ52_02785	COG0706	membrane insertase activity
NRZ52_02790	COG1847	R3H domain protein
NRZ52_02815	COG1192	Involved in chromosome partitioning
NRZ52_02820	COG1475	DNA binding
NRZ52_02830	COG0668	transmembrane transport
NRZ52_02835	COG4481	Protein conserved in bacteria
NRZ52_02840	COG0012	GTP binding
NRZ52_02850	COG0629	single-stranded DNA binding
NRZ52_02860	COG4241	membrane
NRZ52_02865	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NRZ52_02875	COG0305	Participates in initiation and elongation during chromosome replication
NRZ52_02905	COG0745	RESPONSE REGULATOR receiver
NRZ52_02910	COG5002	protein histidine kinase activity
NRZ52_02915	COG4863	YycH protein
NRZ52_02920	COG4853	Protein conserved in bacteria
NRZ52_02925	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NRZ52_02930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRZ52_03000	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NRZ52_03010	COG1164	Oligoendopeptidase f
NRZ52_03030	COG1272	protein, Hemolysin III
NRZ52_03035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRZ52_03080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NRZ52_03085	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NRZ52_03100	COG2814	Major facilitator Superfamily
NRZ52_03105	COG3275	phosphorelay sensor kinase activity
NRZ52_03110	COG3279	Response regulator of the LytR AlgR family
NRZ52_03125	COG0628	permease
NRZ52_03130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRZ52_03130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRZ52_03135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ52_03140	COG1309	transcriptional regulator
NRZ52_03145	COG0463	Glycosyl transferase, family 2
NRZ52_03160	COG0488	(ABC) transporter
NRZ52_03175	COG1216	Glycosyl transferase, family 2
NRZ52_03185	COG1216	Glycosyl transferase, family 2
NRZ52_03190	COG1607	acyl-coa hydrolase
NRZ52_03200	COG0840	transmembrane signaling receptor activity
NRZ52_03215	COG0438	transferase activity, transferring glycosyl groups
NRZ52_03225	COG0477	Major facilitator Superfamily
NRZ52_03230	COG3279	Response regulator of the LytR AlgR family
NRZ52_03240	COG2879	small protein
NRZ52_03245	COG3706	GGDEF domain
NRZ52_03250	COG0351	phosphomethylpyrimidine kinase
NRZ52_03255	COG4585	Histidine kinase
NRZ52_03255	COG2203	Gaf domain
NRZ52_03260	COG2197	response regulator
NRZ52_03270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRZ52_03275	COG1011	Hydrolase
NRZ52_03280	COG2873	o-acetylhomoserine
NRZ52_03290	COG0460	homoserine dehydrogenase
NRZ52_03300	COG1609	Transcriptional regulator
NRZ52_03305	COG2755	lipolytic protein G-D-S-L family
NRZ52_03310	COG1131	(ABC) transporter
NRZ52_03315	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NRZ52_03325	COG2814	Major facilitator Superfamily
NRZ52_03330	COG0561	phosphatase activity
NRZ52_03335	COG2233	PERMEase
NRZ52_03340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NRZ52_03350	COG2363	Small membrane protein
NRZ52_03360	COG3773	Cell wall hydrolase
NRZ52_03375	COG0280	phosphate acetyltransferase
NRZ52_03400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ52_03405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ52_03410	COG1120	ATPase activity
NRZ52_03415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ52_03420	COG1078	dGTPase activity
NRZ52_03430	COG1994	Peptidase M50
NRZ52_03440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ52_03445	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ52_03450	COG0789	Transcriptional regulator
NRZ52_03455	COG2814	Major facilitator Superfamily
NRZ52_03480	COG1619	proteins homologs of microcin C7 resistance protein MccF
NRZ52_03485	COG4506	Protein conserved in bacteria
NRZ52_03495	COG1595	DNA-templated transcription, initiation
NRZ52_03515	COG2234	aminopeptidase activity
NRZ52_03525	COG0024	Methionine aminopeptidase
NRZ52_03530	COG1131	(ABC) transporter
NRZ52_03535	COG0842	Transport permease protein
NRZ52_03540	COG4585	Histidine kinase
NRZ52_03545	COG2197	response regulator
NRZ52_03565	COG3300	MHYT domain
NRZ52_03565	COG5001	Diguanylate cyclase
NRZ52_03575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ52_03580	COG2181	nitrate reductase activity
NRZ52_03580	COG0247	lactate metabolic process
NRZ52_03590	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRZ52_03595	COG1960	acyl-CoA dehydrogenase activity
NRZ52_03600	COG1960	acyl-CoA dehydrogenase activity
NRZ52_03610	COG3343	RNA polymerase activity
NRZ52_03620	COG4821	SIS domain
NRZ52_03640	COG1494	fructose-1,6-bisphosphatase
NRZ52_03645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NRZ52_03665	COG2890	protein-(glutamine-N5) methyltransferase activity
NRZ52_03680	COG0009	L-threonylcarbamoyladenylate synthase
NRZ52_03700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NRZ52_03705	COG2259	Doxx family
NRZ52_03710	COG2190	(PTS) system
NRZ52_03720	COG0698	ribose 5-phosphate isomerase
NRZ52_03755	COG0356	it plays a direct role in the translocation of protons across the membrane
NRZ52_03805	COG5001	Diguanylate cyclase
NRZ52_03805	COG3300	MHYT domain
NRZ52_03820	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ52_03840	COG0839	Belongs to the complex I subunit 6 family
NRZ52_03850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NRZ52_03855	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ52_03860	COG1007	ATP synthesis coupled electron transport
NRZ52_03865	COG4836	Membrane
NRZ52_03880	COG2385	sporulation resulting in formation of a cellular spore
NRZ52_03885	COG3279	Response regulator of the LytR AlgR family
NRZ52_03900	COG0739	heme binding
NRZ52_03910	COG1609	Transcriptional regulator
NRZ52_03925	COG0489	protein tyrosine kinase activity
NRZ52_03930	COG3944	biosynthesis protein
NRZ52_03935	COG0489	protein tyrosine kinase activity
NRZ52_03940	COG4464	protein tyrosine phosphatase activity
NRZ52_03945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NRZ52_03965	COG1216	Glycosyl transferase, family 2
NRZ52_04005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRZ52_04010	COG0745	RESPONSE REGULATOR receiver
NRZ52_04015	COG5002	protein histidine kinase activity
NRZ52_04030	COG2271	Major facilitator Superfamily
NRZ52_04050	COG1136	(ABC) transporter
NRZ52_04055	COG0577	efflux transmembrane transporter activity
NRZ52_04095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NRZ52_04100	COG4715	Zinc finger, swim domain protein
NRZ52_04125	COG3584	3D domain protein
NRZ52_04125	COG1388	LysM domain
NRZ52_04130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NRZ52_04135	COG1215	transferase activity, transferring glycosyl groups
NRZ52_04145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ52_04150	COG0791	NLP P60 protein
NRZ52_04150	COG1388	LysM domain
NRZ52_04160	COG1368	sulfuric ester hydrolase activity
NRZ52_04170	COG2389	metal-binding protein
NRZ52_04180	COG1620	l-lactate permease
NRZ52_04190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NRZ52_04195	COG1294	oxidase, subunit
NRZ52_04200	COG1271	oxidase subunit
NRZ52_04210	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NRZ52_04215	COG0583	DNA-binding transcription factor activity
NRZ52_04220	COG1511	domain protein
NRZ52_04240	COG0346	lactoylglutathione lyase activity
NRZ52_04250	COG1301	dicarboxylic acid transport
NRZ52_04255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NRZ52_04265	COG1447	Phosphotransferase system cellobiose-specific component IIA
NRZ52_04285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NRZ52_04290	COG1447	Phosphotransferase system cellobiose-specific component IIA
NRZ52_04295	COG1486	melibiose metabolic process
NRZ52_04315	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NRZ52_04315	COG3933	PFAM sigma-54 factor interaction domain-containing protein
NRZ52_04325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRZ52_04330	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NRZ52_04335	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NRZ52_04350	COG1739	Uncharacterized protein family UPF0029
NRZ52_04355	COG1307	EDD domain protein, DegV family
NRZ52_04360	COG1733	regulation of RNA biosynthetic process
NRZ52_04365	COG1388	LysM domain
NRZ52_04365	COG0791	NLP P60 protein
NRZ52_04370	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NRZ52_04375	COG1040	competence protein
NRZ52_04380	COG1278	Cold shock
NRZ52_04385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NRZ52_04415	COG1131	(ABC) transporter
NRZ52_04440	COG2884	Cell division ATP-binding protein ftsE
NRZ52_04445	COG2177	Part of the ABC transporter FtsEX involved in
NRZ52_04450	COG0793	Belongs to the peptidase S41A family
NRZ52_04450	COG3409	Peptidoglycan-binding domain 1 protein
NRZ52_04455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRZ52_04460	COG1132	(ABC) transporter
NRZ52_04470	COG0488	(ABC) transporter
NRZ52_04475	COG0655	NAD(P)H dehydrogenase (quinone) activity
NRZ52_04485	COG0583	DNA-binding transcription factor activity
NRZ52_04520	COG0789	Transcriptional regulator
NRZ52_04535	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRZ52_04545	COG1950	PFAM Membrane protein of
NRZ52_04565	COG0110	maltose O-acetyltransferase activity
NRZ52_04570	COG0457	Tetratricopeptide repeat
NRZ52_04575	COG0492	ferredoxin-NADP+ reductase activity
NRZ52_04585	COG1051	belongs to the nudix hydrolase family
NRZ52_04595	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NRZ52_04605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ52_04615	COG2323	membrane
NRZ52_04630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ52_04650	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NRZ52_04725	COG0457	Tetratricopeptide repeat
NRZ52_04745	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NRZ52_04760	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRZ52_04795	COG1346	cytolysis
NRZ52_04800	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRZ52_04805	COG1647	Serine aminopeptidase, S33
NRZ52_04810	COG0557	exoribonuclease II activity
NRZ52_04875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ52_04890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NRZ52_04900	COG0840	transmembrane signaling receptor activity
NRZ52_04900	COG3290	protein histidine kinase activity
NRZ52_04915	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NRZ52_04920	COG1252	NADH dehydrogenase
NRZ52_04930	COG1733	regulation of RNA biosynthetic process
NRZ52_04935	COG2814	Major facilitator Superfamily
NRZ52_04940	COG0656	L-ascorbic acid biosynthetic process
NRZ52_04955	COG2910	NAD(P)H-binding
NRZ52_04960	COG1115	amino acid carrier protein
NRZ52_04965	COG1115	amino acid carrier protein
NRZ52_04970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ52_04975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ52_04995	COG1611	Belongs to the LOG family
NRZ52_05010	COG0783	Belongs to the Dps family
NRZ52_05015	COG1115	amino acid carrier protein
NRZ52_05020	COG0490	domain, Protein
NRZ52_05025	COG0475	glutathione-regulated potassium exporter activity
NRZ52_05040	COG1741	Belongs to the pirin family
NRZ52_05045	COG3227	Zinc metalloprotease (Elastase)
NRZ52_05050	COG2151	metal-sulfur cluster biosynthetic enzyme
NRZ52_05085	COG5002	protein histidine kinase activity
NRZ52_05090	COG0745	RESPONSE REGULATOR receiver
NRZ52_05095	COG1376	ErfK ybiS ycfS ynhG family protein
NRZ52_05105	COG0586	Pfam SNARE associated Golgi protein
NRZ52_05145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ52_05165	COG0531	amino acid
NRZ52_05170	COG2814	Major facilitator Superfamily
NRZ52_05195	COG0840	transmembrane signaling receptor activity
NRZ52_05200	COG0011	TIGRFAM Protein of
NRZ52_05215	COG1686	Belongs to the peptidase S11 family
NRZ52_05225	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRZ52_05225	COG1024	Enoyl-CoA hydratase
NRZ52_05230	COG0183	Belongs to the thiolase family
NRZ52_05240	COG1960	acyl-CoA dehydrogenase activity
NRZ52_05245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ52_05250	COG1309	transcriptional regulator
NRZ52_05300	COG1393	Belongs to the ArsC family
NRZ52_05310	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NRZ52_05315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ52_05330	COG2011	ABC-type metal ion transport system permease component
NRZ52_05335	COG1464	Belongs to the NlpA lipoprotein family
NRZ52_05340	COG1464	Belongs to the NlpA lipoprotein family
NRZ52_05345	COG0396	ATPase activity
NRZ52_05350	COG0719	Fe-S assembly protein
NRZ52_05355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRZ52_05360	COG0822	iron-sulfur transferase activity
NRZ52_05365	COG0719	Fe-S assembly protein
NRZ52_05370	COG0737	Belongs to the 5'-nucleotidase family
NRZ52_05375	COG3377	Domain of unknown function (DUF1805)
NRZ52_05385	COG0739	heme binding
NRZ52_05410	COG4377	Putative membrane peptidase family (DUF2324)
NRZ52_05415	COG0789	Transcriptional regulator
NRZ52_05425	COG4470	Protein conserved in bacteria
NRZ52_05440	COG1494	fructose-1,6-bisphosphatase
NRZ52_05445	COG2445	Protein of unknown function DUF86
NRZ52_05455	COG0647	UMP catabolic process
NRZ52_05465	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRZ52_05475	COG1358	cellular component organization or biogenesis
NRZ52_05495	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NRZ52_05500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NRZ52_05510	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NRZ52_05515	COG4837	Protein of unknown function (DUF1462)
NRZ52_05560	COG0390	transport system, permease component
NRZ52_05565	COG2274	protein secretion by the type I secretion system
NRZ52_05575	COG1252	NADH dehydrogenase
NRZ52_05590	COG0316	Belongs to the HesB IscA family
NRZ52_05610	COG1683	Conserved Protein
NRZ52_05625	COG3708	Transcriptional regulator
NRZ52_05640	COG1252	NADH dehydrogenase
NRZ52_05655	COG3584	3D domain protein
NRZ52_05670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NRZ52_05675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NRZ52_05685	COG1268	BioY protein
NRZ52_05695	COG2050	protein possibly involved in aromatic compounds catabolism
NRZ52_05715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NRZ52_05720	COG5018	Exonuclease
NRZ52_05740	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRZ52_05750	COG2267	carboxylic ester hydrolase activity
NRZ52_05755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRZ52_05760	COG1522	sequence-specific DNA binding
NRZ52_05765	COG0436	Aminotransferase
NRZ52_05770	COG1098	S1 RNA binding domain
NRZ52_05775	COG2155	Conserved Protein
NRZ52_05790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NRZ52_05795	COG1285	pathogenesis
NRZ52_05830	COG0544	peptidyl-prolyl cis-trans isomerase activity
NRZ52_05925	COG1595	DNA-templated transcription, initiation
NRZ52_05940	COG1404	Belongs to the peptidase S8 family
NRZ52_05960	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NRZ52_05970	COG0058	SHG alpha-glucan phosphorylase activity
NRZ52_05995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NRZ52_06000	COG1575	Belongs to the MenA family. Type 1 subfamily
NRZ52_06005	COG1169	isochorismate synthase
NRZ52_06015	COG0596	Alpha beta hydrolase
NRZ52_06020	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NRZ52_06030	COG4948	Mandelate Racemase Muconate Lactonizing
NRZ52_06055	COG3964	amidohydrolase
NRZ52_06075	COG2188	Transcriptional regulator
NRZ52_06100	COG0577	efflux transmembrane transporter activity
NRZ52_06105	COG1136	(ABC) transporter
NRZ52_06110	COG0577	efflux transmembrane transporter activity
NRZ52_06120	COG2205	protein histidine kinase activity
NRZ52_06125	COG0745	RESPONSE REGULATOR receiver
NRZ52_06130	COG0640	Transcriptional regulator
NRZ52_06135	COG5658	integral membrane protein
NRZ52_06145	COG3708	Transcriptional regulator
NRZ52_06145	COG2207	Transcriptional regulator
NRZ52_06150	COG1136	(ABC) transporter
NRZ52_06165	COG0586	Pfam SNARE associated Golgi protein
NRZ52_06180	COG1136	(ABC) transporter
NRZ52_06185	COG0577	efflux transmembrane transporter activity
NRZ52_06200	COG1597	lipid kinase activity
NRZ52_06205	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NRZ52_06235	COG0745	RESPONSE REGULATOR receiver
NRZ52_06240	COG5002	protein histidine kinase activity
NRZ52_06290	COG1842	Phage shock protein A
NRZ52_06315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ52_06335	COG1294	oxidase, subunit
NRZ52_06340	COG1271	oxidase subunit
NRZ52_06345	COG0288	reversible hydration of carbon dioxide
NRZ52_06375	COG0494	nUDIX hydrolase
NRZ52_06400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ52_06405	COG1116	anion transmembrane transporter activity
NRZ52_06410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NRZ52_06435	COG1368	sulfuric ester hydrolase activity
NRZ52_06440	COG2267	carboxylic ester hydrolase activity
NRZ52_06445	COG4191	Histidine kinase
NRZ52_06450	COG5002	protein histidine kinase activity
NRZ52_06460	COG1349	DNA-binding transcription factor activity
NRZ52_06465	COG0546	phosphoglycolate phosphatase activity
NRZ52_06505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ52_06515	COG0521	Mo-molybdopterin cofactor biosynthetic process
NRZ52_06525	COG0438	transferase activity, transferring glycosyl groups
NRZ52_06530	COG0671	phosphoesterase, PA-phosphatase related
NRZ52_06535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NRZ52_06540	COG2267	carboxylic ester hydrolase activity
NRZ52_06565	COG5504	Zn-dependent protease
NRZ52_06575	COG1794	racemase activity, acting on amino acids and derivatives
NRZ52_06590	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NRZ52_06595	COG1242	4 iron, 4 sulfur cluster binding
NRZ52_06615	COG1136	(ABC) transporter
NRZ52_06625	COG0582	viral genome integration into host DNA
NRZ52_06630	COG0490	domain, Protein
NRZ52_06635	COG0475	glutathione-regulated potassium exporter activity
NRZ52_06640	COG2814	Major facilitator Superfamily
NRZ52_06685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NRZ52_06695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ52_06715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NRZ52_06720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ52_06730	COG0303	'Molybdopterin
NRZ52_06735	COG1763	Mo-molybdopterin cofactor biosynthetic process
NRZ52_06740	COG0314	molybdopterin synthase activity
NRZ52_06765	COG1329	Transcriptional regulator
NRZ52_06785	COG3832	glyoxalase III activity
NRZ52_06795	COG2814	Major facilitator Superfamily
NRZ52_06800	COG2081	HI0933 family
NRZ52_06805	COG2244	polysaccharide biosynthetic process
NRZ52_06810	COG1187	pseudouridine synthase activity
NRZ52_06815	COG1349	DNA-binding transcription factor activity
NRZ52_06820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRZ52_06830	COG1523	belongs to the glycosyl hydrolase 13 family
NRZ52_06835	COG0510	thiamine kinase activity
NRZ52_06850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ52_06860	COG1363	Peptidase, m42
NRZ52_06865	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
NRZ52_06870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ52_06880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ52_06890	COG1674	ftsk spoiiie
NRZ52_06905	COG0789	Transcriptional regulator
NRZ52_06910	COG0697	spore germination
NRZ52_06915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ52_06940	COG2309	aminopeptidase activity
NRZ52_06950	COG3118	belongs to the thioredoxin family
NRZ52_06955	COG4851	CamS sex pheromone cAM373 precursor
NRZ52_06980	COG4974	Belongs to the 'phage' integrase family
NRZ52_06990	COG1609	Transcriptional regulator
NRZ52_07025	COG0666	response to abiotic stimulus
NRZ52_07035	COG0745	RESPONSE REGULATOR receiver
NRZ52_07045	COG2267	carboxylic ester hydrolase activity
NRZ52_07050	COG0123	including yeast histone deacetylase and acetoin utilization protein
NRZ52_07055	COG0517	IMP dehydrogenase activity
NRZ52_07060	COG0454	-acetyltransferase
NRZ52_07065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRZ52_07075	COG1595	DNA-templated transcription, initiation
NRZ52_07105	COG0626	cystathionine gamma-synthase activity
NRZ52_07110	COG1956	GAF domain-containing protein
NRZ52_07115	COG1309	transcriptional regulator
NRZ52_07120	COG0697	spore germination
NRZ52_07125	COG0583	DNA-binding transcription factor activity
NRZ52_07135	COG1104	cysteine desulfurase activity
NRZ52_07150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRZ52_07160	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NRZ52_07175	COG3874	Sporulation protein YtfJ
NRZ52_07180	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NRZ52_07185	COG0827	DNA restriction-modification system
NRZ52_07210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ52_07255	COG0589	response to stress
NRZ52_07260	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_07275	COG1476	TRANSCRIPTIONal
NRZ52_07285	COG0662	Cupin 2, conserved barrel domain protein
NRZ52_07335	COG0006	proline dipeptidase activity
NRZ52_07350	COG4109	DRTGG domain
NRZ52_07370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NRZ52_07385	COG0587	DNA-directed DNA polymerase activity
NRZ52_07390	COG0281	malic enzyme
NRZ52_07395	COG1725	Transcriptional regulator
NRZ52_07420	COG3030	protein affecting phage T7 exclusion by the F plasmid
NRZ52_07425	COG0628	permease
NRZ52_07435	COG0372	Belongs to the citrate synthase family
NRZ52_07440	COG0538	isocitrate dehydrogenase activity
NRZ52_07460	COG0745	RESPONSE REGULATOR receiver
NRZ52_07465	COG5002	protein histidine kinase activity
NRZ52_07470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ52_07470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ52_07480	COG1971	Probably functions as a manganese efflux pump
NRZ52_07485	COG0237	dephospho-CoA kinase activity
NRZ52_07490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRZ52_07495	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NRZ52_07505	COG3611	Membrane attachment protein
NRZ52_07510	COG1484	DNA-dependent DNA replication
NRZ52_07520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NRZ52_07545	COG1363	Peptidase, m42
NRZ52_07550	COG1309	transcriptional regulator
NRZ52_07555	COG1566	PFAM secretion protein HlyD family protein
NRZ52_07560	COG2814	Major facilitator Superfamily
NRZ52_07570	COG1418	mRNA catabolic process
NRZ52_07580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRZ52_07625	COG1286	toxin biosynthetic process
NRZ52_07630	COG1796	DNA polymerase
NRZ52_07630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NRZ52_07640	COG1187	pseudouridine synthase activity
NRZ52_07645	COG1114	Component of the transport system for branched-chain amino acids
NRZ52_07650	COG5386	Cell surface protein
NRZ52_07655	COG5386	Cell surface protein
NRZ52_07670	COG1120	ATPase activity
NRZ52_07675	COG4509	Sortase family
NRZ52_07690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NRZ52_07695	COG4895	conserved protein (DUF2196)
NRZ52_07705	COG0745	RESPONSE REGULATOR receiver
NRZ52_07710	COG2205	protein histidine kinase activity
NRZ52_07715	COG1131	(ABC) transporter
NRZ52_07740	COG2318	DinB family
NRZ52_07755	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ52_07760	COG1309	transcriptional regulator
NRZ52_07765	COG1024	Enoyl-CoA hydratase
NRZ52_07770	COG2086	electron transfer activity
NRZ52_07775	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NRZ52_07780	COG3118	belongs to the thioredoxin family
NRZ52_07790	COG1719	4-vinyl reductase, 4VR
NRZ52_07795	COG2009	succinate dehydrogenase
NRZ52_07800	COG1053	succinate dehydrogenase
NRZ52_07805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NRZ52_07810	COG0824	Thioesterase
NRZ52_07815	COG1876	peptidase activity
NRZ52_07820	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ52_07825	COG1360	Flagellar Motor Protein
NRZ52_07830	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NRZ52_07835	COG4152	abc transporter atp-binding protein
NRZ52_07840	COG1668	transmembrane transport
NRZ52_07845	COG1959	2 iron, 2 sulfur cluster binding
NRZ52_07855	COG0697	spore germination
NRZ52_07860	COG1396	sequence-specific DNA binding
NRZ52_07865	COG1983	PspC domain protein
NRZ52_07870	COG0402	S-adenosylhomocysteine deaminase activity
NRZ52_07875	COG2233	PERMEase
NRZ52_07880	COG2197	response regulator
NRZ52_07895	COG1309	transcriptional regulator
NRZ52_07905	COG2814	Major facilitator Superfamily
NRZ52_07915	COG5401	PFAM Sporulation and spore germination
NRZ52_07930	COG0622	Phosphoesterase
NRZ52_07950	COG0457	Tetratricopeptide repeat
NRZ52_07995	COG1067	ATP-dependent peptidase activity
NRZ52_07995	COG0470	DNA polymerase III
NRZ52_08010	COG1764	response to oxidative stress
NRZ52_08015	COG1846	Transcriptional regulator
NRZ52_08025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ52_08035	COG1587	Uroporphyrinogen-III synthase
NRZ52_08040	COG0113	porphobilinogen synthase activity
NRZ52_08050	COG1388	LysM domain
NRZ52_08065	COG0285	dihydrofolate synthase activity
NRZ52_08085	COG1077	Cell shape determining protein MreB Mrl
NRZ52_08105	COG2894	cell division
NRZ52_08110	COG0739	heme binding
NRZ52_08115	COG1994	Peptidase M50
NRZ52_08120	COG1530	ribonuclease E activity
NRZ52_08125	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NRZ52_08130	COG2868	ribosomal protein
NRZ52_08140	COG3290	protein histidine kinase activity
NRZ52_08150	COG0745	RESPONSE REGULATOR receiver
NRZ52_08155	COG5002	protein histidine kinase activity
NRZ52_08160	COG1136	(ABC) transporter
NRZ52_08165	COG0577	efflux transmembrane transporter activity
NRZ52_08170	COG0577	efflux transmembrane transporter activity
NRZ52_08175	COG0077	Prephenate dehydratase
NRZ52_08180	COG2258	MOSC domain
NRZ52_08185	COG1827	regulation of RNA biosynthetic process
NRZ52_08190	COG1104	cysteine desulfurase activity
NRZ52_08195	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NRZ52_08200	COG0157	Belongs to the NadC ModD family
NRZ52_08225	COG0640	Transcriptional regulator
NRZ52_08230	COG0697	spore germination
NRZ52_08240	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NRZ52_08270	COG1862	Preprotein translocase
NRZ52_08280	COG2323	membrane
NRZ52_08285	COG2244	polysaccharide biosynthetic process
NRZ52_08295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ52_08295	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ52_08300	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NRZ52_08305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NRZ52_08305	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NRZ52_08315	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRZ52_08350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NRZ52_08360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NRZ52_08365	COG1959	2 iron, 2 sulfur cluster binding
NRZ52_08370	COG1104	cysteine desulfurase activity
NRZ52_08385	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NRZ52_08405	COG0628	permease
NRZ52_08435	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NRZ52_08440	COG4122	O-methyltransferase activity
NRZ52_08445	COG0826	peptidase U32
NRZ52_08450	COG0826	peptidase U32
NRZ52_08470	COG0768	penicillin binding
NRZ52_08495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NRZ52_08500	COG0626	cystathionine gamma-synthase activity
NRZ52_08505	COG1012	belongs to the aldehyde dehydrogenase family
NRZ52_08505	COG1454	alcohol dehydrogenase
NRZ52_08515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ52_08555	COG2259	Doxx family
NRZ52_08560	COG2514	catechol 2,3-dioxygenase activity
NRZ52_08570	COG3186	Phenylalanine-4-hydroxylase
NRZ52_08575	COG1404	Belongs to the peptidase S8 family
NRZ52_08610	COG2267	carboxylic ester hydrolase activity
NRZ52_08620	COG1785	Belongs to the alkaline phosphatase family
NRZ52_08630	COG2357	RelA SpoT domain protein
NRZ52_08635	COG0778	Nitroreductase
NRZ52_08670	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NRZ52_08675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NRZ52_08685	COG1534	Rna-binding protein
NRZ52_08695	COG1713	HD superfamily hydrolase involved in NAD metabolism
NRZ52_08700	COG0799	negative regulation of ribosome biogenesis
NRZ52_08705	COG2226	methyltransferase
NRZ52_08710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRZ52_08715	COG1555	photosystem II stabilization
NRZ52_08715	COG1596	polysaccharide export
NRZ52_08720	COG2131	deaminase
NRZ52_08725	COG0658	competence protein
NRZ52_08725	COG2333	competence protein COMEC
NRZ52_08735	COG1466	dna polymerase III delta subunit
NRZ52_08760	COG1733	regulation of RNA biosynthetic process
NRZ52_08765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRZ52_08795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NRZ52_08800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NRZ52_08805	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NRZ52_08810	COG1610	YqeY-like protein
NRZ52_08825	COG1702	phosphate starvation-inducible protein PhoH
NRZ52_08830	COG1480	7TM receptor with intracellular HD hydrolase
NRZ52_08840	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NRZ52_08845	COG0295	cytidine deaminase activity
NRZ52_08850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NRZ52_08865	COG0517	IMP dehydrogenase activity
NRZ52_08875	COG0358	DNA primase activity
NRZ52_08880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NRZ52_08885	COG2010	Cytochrome c
NRZ52_08890	COG2384	SAM-dependent methyltransferase
NRZ52_08895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NRZ52_08925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ52_08930	COG1121	(ABC) transporter
NRZ52_08935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NRZ52_08940	COG0735	belongs to the Fur family
NRZ52_08965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NRZ52_08970	COG0477	Major facilitator Superfamily
NRZ52_08975	COG0768	penicillin binding
NRZ52_08980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NRZ52_08985	COG0573	inorganic phosphate transmembrane transporter activity
NRZ52_08990	COG0581	inorganic phosphate transmembrane transporter activity
NRZ52_09000	COG0704	Plays a role in the regulation of phosphate uptake
NRZ52_09005	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NRZ52_09010	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NRZ52_09015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NRZ52_09020	COG4483	Protein conserved in bacteria
NRZ52_09025	COG1940	carbohydrate kinase activity
NRZ52_09035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ52_09055	COG0626	cystathionine gamma-synthase activity
NRZ52_09060	COG0626	cystathionine gamma-synthase activity
NRZ52_09065	COG0646	methionine synthase
NRZ52_09065	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NRZ52_09070	COG0646	methionine synthase
NRZ52_09070	COG1410	methionine synthase
NRZ52_09120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRZ52_09125	COG1459	type II secretion system
NRZ52_09135	COG4970	Tfp pilus assembly protein FimT
NRZ52_09205	COG1846	Transcriptional regulator
NRZ52_09210	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NRZ52_09270	COG0270	DNA (cytosine-5-)-methyltransferase activity
NRZ52_09295	COG0582	viral genome integration into host DNA
NRZ52_09340	COG1802	Transcriptional regulator
NRZ52_09340	COG4626	Terminase
NRZ52_09350	COG0740	serine-type endopeptidase activity
NRZ52_09500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NRZ52_09530	COG1725	Transcriptional regulator
NRZ52_09535	COG1131	(ABC) transporter
NRZ52_09570	COG2076	Multidrug Resistance protein
NRZ52_09575	COG2076	Multidrug Resistance protein
NRZ52_09585	COG1609	Transcriptional regulator
NRZ52_09590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ52_09595	COG0095	Lipoate-protein ligase
NRZ52_09625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ52_09635	COG3872	metal-dependent enzyme
NRZ52_09650	COG0006	proline dipeptidase activity
NRZ52_09675	COG3854	ATPases associated with a variety of cellular activities
NRZ52_09720	COG0511	ligase activity, forming carbon-carbon bonds
NRZ52_09725	COG0439	Biotin carboxylase
NRZ52_09730	COG1302	Protein conserved in bacteria
NRZ52_09755	COG0142	geranyltranstransferase activity
NRZ52_09765	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NRZ52_09775	COG0497	DNA recombination
NRZ52_09780	COG0750	zinc metalloprotease
NRZ52_09785	COG0745	RESPONSE REGULATOR receiver
NRZ52_09825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NRZ52_09865	COG3093	addiction module antidote protein HigA
NRZ52_09870	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ52_09880	COG3829	transcription factor binding
NRZ52_09880	COG3290	protein histidine kinase activity
NRZ52_09885	COG0280	phosphate acetyltransferase
NRZ52_09900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRZ52_09905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NRZ52_09910	COG0022	dehydrogenase e1 component
NRZ52_09915	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRZ52_09920	COG0772	Belongs to the SEDS family
NRZ52_09925	COG2323	membrane
NRZ52_09945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ52_09950	COG0765	amino acid transport
NRZ52_09955	COG1126	abc transporter atp-binding protein
NRZ52_09960	COG4129	membrane
NRZ52_09965	COG1376	ErfK ybiS ycfS ynhG family protein
NRZ52_09980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ52_09985	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRZ52_10000	COG1285	pathogenesis
NRZ52_10025	COG1760	l-serine dehydratase
NRZ52_10030	COG1760	l-serine dehydratase
NRZ52_10035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRZ52_10040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ52_10045	COG0300	oxidoreductase activity
NRZ52_10070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NRZ52_10100	COG0737	Belongs to the 5'-nucleotidase family
NRZ52_10105	COG1757	Na H antiporter
NRZ52_10115	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NRZ52_10130	COG1073	alpha beta
NRZ52_10130	COG2226	methyltransferase
NRZ52_10135	COG4106	trans-aconitate 2-methyltransferase activity
NRZ52_10160	COG0307	riboflavin synthase, alpha
NRZ52_10165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ52_10165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ52_10180	COG1073	alpha beta
NRZ52_10185	COG0456	acetyltransferase
NRZ52_10190	COG1609	Transcriptional regulator
NRZ52_10195	COG2056	Na+-H+ antiporter family
NRZ52_10200	COG0596	Alpha beta hydrolase
NRZ52_10210	COG1525	nuclease
NRZ52_10210	COG4085	toxin activity
NRZ52_10210	COG0737	Belongs to the 5'-nucleotidase family
NRZ52_10220	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NRZ52_10220	COG0456	acetyltransferase
NRZ52_10225	COG0656	L-ascorbic acid biosynthetic process
NRZ52_10230	COG0667	Aldo Keto reductase
NRZ52_10250	COG1300	Membrane
NRZ52_10255	COG0735	belongs to the Fur family
NRZ52_10265	COG4974	Belongs to the 'phage' integrase family
NRZ52_10290	COG0598	Magnesium transport protein CorA
NRZ52_10305	COG1846	Transcriptional regulator
NRZ52_10325	COG1131	(ABC) transporter
NRZ52_10330	COG1725	Transcriptional regulator
NRZ52_10335	COG1686	Belongs to the peptidase S11 family
NRZ52_10355	COG0733	neurotransmitter:sodium symporter activity
NRZ52_10380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ52_10395	COG0697	spore germination
NRZ52_10400	COG0561	phosphatase activity
NRZ52_10405	COG4086	secreted protein
NRZ52_10410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRZ52_10420	COG0456	acetyltransferase
NRZ52_10425	COG1547	Domain of unknown function (DUF309)
NRZ52_10450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRZ52_10460	COG2188	Transcriptional regulator
NRZ52_10470	COG3711	transcriptional antiterminator
NRZ52_10475	COG2190	(PTS) system
NRZ52_10475	COG1263	PTS System
NRZ52_10475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ52_10500	COG0778	Nitroreductase
NRZ52_10505	COG2199	diguanylate cyclase activity
NRZ52_10515	COG2084	Dehydrogenase
NRZ52_10550	COG0436	Aminotransferase
NRZ52_10555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRZ52_10575	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_10580	COG1695	Transcriptional regulator
NRZ52_10610	COG0183	Belongs to the thiolase family
NRZ52_10615	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NRZ52_10655	COG3842	ATPase activity
NRZ52_10660	COG0366	Alpha amylase catalytic
NRZ52_10670	COG2182	Extracellular solute-binding protein
NRZ52_10675	COG1175	transmembrane transport
NRZ52_10680	COG3833	ABC-type maltose transport systems, permease component
NRZ52_10685	COG1609	Transcriptional regulator
NRZ52_10690	COG0436	Aminotransferase
NRZ52_10700	COG2205	protein histidine kinase activity
NRZ52_10710	COG3209	COG3209 Rhs family protein
NRZ52_10730	COG2814	Major facilitator Superfamily
NRZ52_10780	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NRZ52_10790	COG1408	metallophosphoesterase
NRZ52_10795	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_10800	COG2200	EAL domain
NRZ52_10820	COG4703	Protein of unknown function (DUF1797)
NRZ52_10830	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NRZ52_10840	COG0517	IMP dehydrogenase activity
NRZ52_10845	COG0583	DNA-binding transcription factor activity
NRZ52_10865	COG0569	domain protein
NRZ52_10870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NRZ52_10880	COG0561	phosphatase activity
NRZ52_10885	COG0242	peptide deformylase activity
NRZ52_10895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NRZ52_10900	COG0022	dehydrogenase e1 component
NRZ52_10950	COG1982	Orn Lys Arg decarboxylase major
NRZ52_10970	COG0483	inositol monophosphate 1-phosphatase activity
NRZ52_10980	COG1217	gtp-binding protein TYPA
NRZ52_10995	COG4896	Protein conserved in bacteria
NRZ52_11005	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NRZ52_11010	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NRZ52_11020	COG0772	Belongs to the SEDS family
NRZ52_11025	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NRZ52_11045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NRZ52_11060	COG3336	cytochrome c oxidase
NRZ52_11070	COG3344	reverse transcriptase
NRZ52_11085	COG2340	Cysteine-rich secretory protein family
NRZ52_11100	COG0406	alpha-ribazole phosphatase activity
NRZ52_11105	COG3679	Belongs to the UPF0342 family
NRZ52_11120	COG0742	ribosomal rna small subunit methyltransferase
NRZ52_11130	COG3314	Sporulation integral membrane protein YlbJ
NRZ52_11135	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRZ52_11140	COG3480	Lon protease (S16) C-terminal proteolytic domain
NRZ52_11150	COG1399	metal-binding, possibly nucleic acid-binding protein
NRZ52_11155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NRZ52_11170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NRZ52_11185	COG4839	cell division protein FtsL
NRZ52_11190	COG0768	penicillin binding
NRZ52_11195	COG0768	penicillin binding
NRZ52_11200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NRZ52_11215	COG0772	Belongs to the SEDS family
NRZ52_11230	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NRZ52_11235	COG0849	cell division
NRZ52_11240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NRZ52_11250	COG1191	sigma factor activity
NRZ52_11255	COG1191	sigma factor activity
NRZ52_11260	COG1873	PFAM PRC-barrel domain
NRZ52_11270	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NRZ52_11280	COG0762	integral membrane protein
NRZ52_11285	COG2302	S4 RNA-binding domain
NRZ52_11290	COG3599	regulation of cell shape
NRZ52_11310	COG0564	pseudouridine synthase activity
NRZ52_11365	COG1011	Hydrolase
NRZ52_11375	COG3069	C4-dicarboxylate transmembrane transporter activity
NRZ52_11395	COG0006	proline dipeptidase activity
NRZ52_11405	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NRZ52_11410	COG1561	YicC-like family, N-terminal region
NRZ52_11430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NRZ52_11435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NRZ52_11440	COG0242	peptide deformylase activity
NRZ52_11450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRZ52_11450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRZ52_11460	COG0631	protein serine/threonine phosphatase activity
NRZ52_11465	COG0515	serine threonine protein kinase
NRZ52_11465	COG2815	serine threonine protein kinase
NRZ52_11475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRZ52_11480	COG1564	THIamine pyrophosphokinase
NRZ52_11495	COG1302	Protein conserved in bacteria
NRZ52_11500	COG1461	Dihydroxyacetone kinase
NRZ52_11505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NRZ52_11520	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NRZ52_11525	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_11530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRZ52_11540	COG1196	nuclear chromosome segregation
NRZ52_11545	COG0552	protein localization to endoplasmic reticulum
NRZ52_11555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NRZ52_11565	COG1837	Belongs to the UPF0109 family
NRZ52_11605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NRZ52_11610	COG0758	DNA mediated transformation
NRZ52_11615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NRZ52_11625	COG4974	Belongs to the 'phage' integrase family
NRZ52_11655	COG0528	UMP kinase activity
NRZ52_11670	COG4589	Belongs to the CDS family
NRZ52_11680	COG0750	zinc metalloprotease
NRZ52_11700	COG0195	Participates in both transcription termination and antitermination
NRZ52_11705	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NRZ52_11710	COG1358	cellular component organization or biogenesis
NRZ52_11720	COG1550	Protein conserved in bacteria
NRZ52_11730	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NRZ52_11735	COG0196	riboflavin kinase activity
NRZ52_11750	COG0726	polysaccharide deacetylase
NRZ52_11755	COG0612	Peptidase, M16
NRZ52_11760	COG1873	PFAM PRC-barrel domain
NRZ52_11765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRZ52_11770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NRZ52_11775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRZ52_11780	COG0527	aspartate kinase activity
NRZ52_11790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NRZ52_11795	COG0740	serine-type endopeptidase activity
NRZ52_11805	COG1674	ftsk spoiiie
NRZ52_11810	COG2188	Transcriptional regulator
NRZ52_11815	COG1744	ABC transporter substrate-binding protein PnrA-like
NRZ52_11820	COG3845	ABC transporter
NRZ52_11825	COG4603	Belongs to the binding-protein-dependent transport system permease family
NRZ52_11830	COG1079	Belongs to the binding-protein-dependent transport system permease family
NRZ52_11835	COG0612	Peptidase, M16
NRZ52_11840	COG0612	Peptidase, M16
NRZ52_11845	COG0300	oxidoreductase activity
NRZ52_11860	COG1426	Protein conserved in bacteria
NRZ52_11865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NRZ52_11885	COG1692	metallophosphoesterase
NRZ52_11890	COG2359	stage V sporulation protein S
NRZ52_11900	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NRZ52_11900	COG0674	pyruvate-flavodoxin oxidoreductase activity
NRZ52_11905	COG1013	pyruvate-flavodoxin oxidoreductase activity
NRZ52_11915	COG4550	Control of competence regulator ComK, YlbF/YmcA
NRZ52_11935	COG1131	(ABC) transporter
NRZ52_11960	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NRZ52_11970	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NRZ52_11975	COG1368	sulfuric ester hydrolase activity
NRZ52_11985	COG3773	Cell wall hydrolase
NRZ52_11990	COG1404	Belongs to the peptidase S8 family
NRZ52_12010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ52_12015	COG1380	Effector of murein hydrolase LrgA
NRZ52_12020	COG1346	cytolysis
NRZ52_12040	COG3300	MHYT domain
NRZ52_12040	COG5001	Diguanylate cyclase
NRZ52_12045	COG0346	lactoylglutathione lyase activity
NRZ52_12050	COG2267	carboxylic ester hydrolase activity
NRZ52_12065	COG2364	Membrane
NRZ52_12075	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NRZ52_12080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NRZ52_12085	COG2169	Transcriptional regulator
NRZ52_12090	COG0708	Exodeoxyribonuclease III
NRZ52_12095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ52_12100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ52_12105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ52_12110	COG1120	ATPase activity
NRZ52_12115	COG2819	hydrolase of the alpha beta superfamily
NRZ52_12135	COG1230	cation diffusion facilitator family transporter
NRZ52_12145	COG1937	Protein conserved in bacteria
NRZ52_12150	COG2608	mercury ion transmembrane transporter activity
NRZ52_12155	COG2217	Heavy metal translocating P-type atpase
NRZ52_12170	COG2116	formate transmembrane transporter activity
NRZ52_12175	COG1408	metallophosphoesterase
NRZ52_12245	COG1113	amino acid transport
NRZ52_12255	COG2322	membrane
NRZ52_12260	COG1979	alcohol dehydrogenase
NRZ52_12265	COG1349	DNA-binding transcription factor activity
NRZ52_12270	COG1105	Belongs to the carbohydrate kinase PfkB family
NRZ52_12275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ52_12275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ52_12275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ52_12280	COG1388	LysM domain
NRZ52_12280	COG3584	3D domain protein
NRZ52_12315	COG0464	growth
NRZ52_12325	COG2860	membrane
NRZ52_12330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NRZ52_12335	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NRZ52_12340	COG0789	Transcriptional regulator
NRZ52_12345	COG0174	glutamine synthetase
NRZ52_12350	COG1695	Transcriptional regulator
NRZ52_12370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NRZ52_12380	COG0737	Belongs to the 5'-nucleotidase family
NRZ52_12385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ52_12390	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NRZ52_12395	COG3639	organic phosphonate transmembrane transporter activity
NRZ52_12525	COG1132	(ABC) transporter
NRZ52_12530	COG1132	(ABC) transporter
NRZ52_12545	COG5632	N-Acetylmuramoyl-L-alanine amidase
NRZ52_12545	COG3409	Peptidoglycan-binding domain 1 protein
NRZ52_12555	COG0730	response to heat
NRZ52_12570	COG1346	cytolysis
NRZ52_12580	COG0583	DNA-binding transcription factor activity
NRZ52_12590	COG1131	(ABC) transporter
NRZ52_12600	COG1473	amidohydrolase
NRZ52_12610	COG0785	Cytochrome C biogenesis protein
NRZ52_12615	COG4846	Membrane protein involved in cytochrome C biogenesis
NRZ52_12650	COG2226	methyltransferase
NRZ52_12675	COG0010	Belongs to the arginase family
NRZ52_12680	COG1329	Transcriptional regulator
NRZ52_12685	COG1902	pentaerythritol trinitrate reductase activity
NRZ52_12690	COG0069	glutamate synthase activity
NRZ52_12695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ52_12700	COG0346	lactoylglutathione lyase activity
NRZ52_12705	COG0400	carboxylic ester hydrolase activity
NRZ52_12710	COG5002	protein histidine kinase activity
NRZ52_12720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ52_12770	COG1396	sequence-specific DNA binding
NRZ52_12785	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ52_12790	COG1268	BioY protein
NRZ52_12795	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ52_12800	COG0183	Belongs to the thiolase family
NRZ52_12815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NRZ52_12825	COG2211	Major facilitator Superfamily
NRZ52_12855	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NRZ52_12860	COG1132	(ABC) transporter
NRZ52_12875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ52_12905	COG0824	Thioesterase
NRZ52_12910	COG4841	protein insertion into membrane
NRZ52_12930	COG0745	RESPONSE REGULATOR receiver
NRZ52_12935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRZ52_12940	COG1832	CoA-binding protein
NRZ52_12945	COG0187	DNA topoisomerase II activity
NRZ52_12950	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NRZ52_12960	COG0673	inositol 2-dehydrogenase activity
NRZ52_12990	COG3344	reverse transcriptase
NRZ52_13005	COG1595	DNA-templated transcription, initiation
NRZ52_13015	COG1316	TRANSCRIPTIONal
NRZ52_13020	COG1301	dicarboxylic acid transport
NRZ52_13025	COG4166	transmembrane transport
NRZ52_13030	COG4166	transmembrane transport
NRZ52_13035	COG4166	transmembrane transport
NRZ52_13040	COG2226	methyltransferase
NRZ52_13085	COG0697	spore germination
NRZ52_13090	COG3383	formate dehydrogenase (NAD+) activity
NRZ52_13095	COG2427	Protein of unknown function (DUF1641)
NRZ52_13100	COG5609	conserved protein (DUF2294)
NRZ52_13105	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRZ52_13115	COG2116	formate transmembrane transporter activity
NRZ52_13120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ52_13125	COG0303	'Molybdopterin
NRZ52_13130	COG0314	molybdopterin synthase activity
NRZ52_13140	COG0489	protein tyrosine kinase activity
NRZ52_13155	COG3326	Membrane
NRZ52_13160	COG2962	Rard protein
NRZ52_13165	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NRZ52_13170	COG1657	PFAM Prenyltransferase squalene oxidase
NRZ52_13180	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_13185	COG1012	belongs to the aldehyde dehydrogenase family
NRZ52_13195	COG4145	pantothenate transmembrane transporter activity
NRZ52_13210	COG0165	Argininosuccinate lyase
NRZ52_13220	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_13240	COG0494	nUDIX hydrolase
NRZ52_13250	COG0716	FMN binding
NRZ52_13290	COG2720	vancomycin resistance protein
NRZ52_13295	COG0765	amino acid transport
NRZ52_13300	COG1126	abc transporter atp-binding protein
NRZ52_13305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ52_13310	COG2514	catechol 2,3-dioxygenase activity
NRZ52_13325	COG1285	pathogenesis
NRZ52_13365	COG0277	FAD linked oxidase domain protein
NRZ52_13370	COG0385	Bile acid
NRZ52_13385	COG2808	Putative FMN-binding domain
NRZ52_13395	COG0457	Tetratricopeptide repeat
NRZ52_13405	COG0604	alcohol dehydrogenase
NRZ52_13410	COG0640	Transcriptional regulator
NRZ52_13440	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ52_13470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NRZ52_13475	COG1164	Oligoendopeptidase f
NRZ52_13480	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NRZ52_13485	COG1193	negative regulation of DNA recombination
NRZ52_13515	COG0583	DNA-binding transcription factor activity
NRZ52_13550	COG0384	phenazine biosynthesis protein PhzF
NRZ52_13555	COG3739	integral membrane protein
NRZ52_13560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ52_13565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ52_13570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ52_13585	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NRZ52_13590	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NRZ52_13625	COG1191	sigma factor activity
NRZ52_13650	COG1733	regulation of RNA biosynthetic process
NRZ52_13655	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRZ52_13660	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ52_13670	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_13680	COG0384	phenazine biosynthesis protein PhzF
NRZ52_13705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ52_13725	COG1733	regulation of RNA biosynthetic process
NRZ52_13730	COG1733	regulation of RNA biosynthetic process
NRZ52_13735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NRZ52_13740	COG0673	inositol 2-dehydrogenase activity
NRZ52_13745	COG2188	Transcriptional regulator
NRZ52_13750	COG1733	regulation of RNA biosynthetic process
NRZ52_13755	COG1393	Belongs to the ArsC family
NRZ52_13785	COG0814	amino acid
NRZ52_13790	COG0346	lactoylglutathione lyase activity
NRZ52_13805	COG2814	Major facilitator Superfamily
NRZ52_13810	COG0656	L-ascorbic acid biosynthetic process
NRZ52_13825	COG1733	regulation of RNA biosynthetic process
NRZ52_13830	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRZ52_13830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRZ52_13835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ52_13835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ52_13845	COG0840	transmembrane signaling receptor activity
NRZ52_13860	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_13870	COG0604	alcohol dehydrogenase
NRZ52_13870	COG3321	synthase
NRZ52_13880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NRZ52_13885	COG0604	alcohol dehydrogenase
NRZ52_13890	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NRZ52_13895	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NRZ52_13905	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NRZ52_13910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRZ52_13920	COG1070	Carbohydrate kinase
NRZ52_13925	COG2706	6-phosphogluconolactonase activity
NRZ52_13930	COG3813	Protein conserved in bacteria
NRZ52_13935	COG1357	PFAM Pentapeptide repeats (8 copies)
NRZ52_13940	COG0697	spore germination
NRZ52_13980	COG0789	Transcriptional regulator
NRZ52_13985	COG1253	flavin adenine dinucleotide binding
NRZ52_14010	COG0477	Major facilitator Superfamily
NRZ52_14020	COG0500	methyltransferase
NRZ52_14050	COG0628	permease
NRZ52_14070	COG0577	efflux transmembrane transporter activity
NRZ52_14070	COG1136	(ABC) transporter
NRZ52_14080	COG0110	maltose O-acetyltransferase activity
NRZ52_14085	COG1940	carbohydrate kinase activity
NRZ52_14090	COG0346	lactoylglutathione lyase activity
NRZ52_14115	COG2365	Tyrosine phosphatase family
NRZ52_14125	COG1011	Hydrolase
NRZ52_14150	COG1131	(ABC) transporter
NRZ52_14160	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_14180	COG0778	Nitroreductase
NRZ52_14185	COG1733	regulation of RNA biosynthetic process
NRZ52_14200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NRZ52_14230	COG0789	Transcriptional regulator
NRZ52_14255	COG1288	antiporter activity
NRZ52_14260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NRZ52_14275	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NRZ52_14310	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRZ52_14320	COG2031	fatty acid transporter
NRZ52_14335	COG2814	Major facilitator Superfamily
NRZ52_14340	COG1846	Transcriptional regulator
NRZ52_14355	COG0477	Major facilitator Superfamily
NRZ52_14400	COG3409	Peptidoglycan-binding domain 1 protein
NRZ52_14400	COG5632	N-Acetylmuramoyl-L-alanine amidase
NRZ52_14415	COG2207	Transcriptional regulator
NRZ52_14415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ52_14420	COG0662	Cupin 2, conserved barrel domain protein
NRZ52_14440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRZ52_14470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ52_14475	COG2808	Putative FMN-binding domain
NRZ52_14480	COG0456	acetyltransferase
NRZ52_14485	COG1846	Transcriptional regulator
NRZ52_14490	COG2364	Membrane
NRZ52_14500	COG5002	protein histidine kinase activity
NRZ52_14500	COG3850	Histidine kinase
NRZ52_14525	COG1132	(ABC) transporter
NRZ52_14555	COG0577	efflux transmembrane transporter activity
NRZ52_14575	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NRZ52_14580	COG0789	Transcriptional regulator
NRZ52_14605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ52_14615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ52_14620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ52_14635	COG1476	TRANSCRIPTIONal
NRZ52_14655	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NRZ52_14705	COG4895	conserved protein (DUF2196)
NRZ52_14715	COG2814	Major facilitator Superfamily
NRZ52_14750	COG2169	Transcriptional regulator
NRZ52_14770	COG0346	lactoylglutathione lyase activity
NRZ52_14785	COG1522	sequence-specific DNA binding
NRZ52_14790	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_14805	COG0443	Heat shock 70 kDa protein
NRZ52_14820	COG0640	Transcriptional regulator
NRZ52_14825	COG0346	lactoylglutathione lyase activity
NRZ52_14830	COG0798	PFAM Bile acid sodium symporter
NRZ52_14870	COG0577	efflux transmembrane transporter activity
NRZ52_14875	COG1136	(ABC) transporter
NRZ52_14880	COG4641	Protein conserved in bacteria
NRZ52_14885	COG2267	carboxylic ester hydrolase activity
NRZ52_14890	COG1575	Belongs to the MenA family. Type 1 subfamily
NRZ52_14900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ52_14915	COG1329	Transcriptional regulator
NRZ52_14945	COG5609	conserved protein (DUF2294)
NRZ52_14950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NRZ52_14960	COG0288	reversible hydration of carbon dioxide
NRZ52_14965	COG0415	Belongs to the DNA photolyase family
NRZ52_15005	COG0598	Magnesium transport protein CorA
NRZ52_15015	COG0753	catalase activity
NRZ52_15065	COG0702	epimerase
NRZ52_15105	COG1063	alcohol dehydrogenase
NRZ52_15125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ52_15135	COG0574	Belongs to the PEP-utilizing enzyme family
NRZ52_15135	COG3848	Pyruvate phosphate dikinase
NRZ52_15150	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NRZ52_15170	COG3314	Sporulation integral membrane protein YlbJ
NRZ52_15185	COG1960	acyl-CoA dehydrogenase activity
NRZ52_15200	COG0640	Transcriptional regulator
NRZ52_15205	COG0860	N-Acetylmuramoyl-L-alanine amidase
NRZ52_15210	COG3142	Participates in the control of copper homeostasis
NRZ52_15225	COG1414	Transcriptional regulator
NRZ52_15230	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NRZ52_15235	COG1984	allophanate hydrolase subunit 2
NRZ52_15270	COG0768	penicillin binding
NRZ52_15310	COG4335	DNA alkylation repair
NRZ52_15320	COG0833	amino acid
NRZ52_15330	COG0730	response to heat
NRZ52_15375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ52_15395	COG0456	acetyltransferase
NRZ52_15400	COG2207	Transcriptional regulator
NRZ52_15440	COG1846	Transcriptional regulator
NRZ52_15445	COG0778	Nitroreductase
NRZ52_15455	COG0714	Associated with various cellular activities
NRZ52_15485	COG3403	YqcI/YcgG family
NRZ52_15490	COG1280	lysine exporter protein (LysE YggA)
NRZ52_15500	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NRZ52_15505	COG1846	Transcriptional regulator
NRZ52_15520	COG1116	anion transmembrane transporter activity
NRZ52_15525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ52_15530	COG0753	catalase activity
NRZ52_15535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NRZ52_15555	COG0714	Associated with various cellular activities
NRZ52_15580	COG0346	lactoylglutathione lyase activity
NRZ52_15595	COG3279	Response regulator of the LytR AlgR family
NRZ52_15605	COG4377	Putative membrane peptidase family (DUF2324)
NRZ52_15620	COG3655	Transcriptional regulator
NRZ52_15630	COG1785	Belongs to the alkaline phosphatase family
NRZ52_15640	COG3239	Fatty acid desaturase
NRZ52_15645	COG1690	Belongs to the RtcB family
NRZ52_15650	COG0833	amino acid
NRZ52_15655	COG1414	Transcriptional regulator
NRZ52_15660	COG4187	Peptidase family M20/M25/M40
NRZ52_15665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRZ52_15680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ52_15695	COG2329	Antibiotic biosynthesis monooxygenase
NRZ52_15735	COG2390	Transcriptional regulator
NRZ52_15745	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRZ52_15750	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRZ52_15770	COG1309	transcriptional regulator
NRZ52_15775	COG2814	Major facilitator Superfamily
NRZ52_15785	COG1388	LysM domain
NRZ52_15785	COG3584	3D domain protein
NRZ52_15820	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NRZ52_15820	COG1605	Chorismate mutase
NRZ52_15835	COG0287	Prephenate dehydrogenase
NRZ52_15850	COG1309	transcriptional regulator
NRZ52_15855	COG2409	Drug exporters of the RND superfamily
NRZ52_15855	COG1033	growth of symbiont in host cell
NRZ52_15865	COG4974	Belongs to the 'phage' integrase family
NRZ52_15960	COG0488	(ABC) transporter
NRZ52_15965	COG1368	sulfuric ester hydrolase activity
NRZ52_15970	COG0861	Integral membrane protein TerC family
NRZ52_15985	COG4912	Dna alkylation repair
NRZ52_16005	COG2318	DinB family
NRZ52_16010	COG0697	spore germination
NRZ52_16030	COG2746	aminoglycoside 3-N-acetyltransferase activity
NRZ52_16075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NRZ52_16080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ52_16085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NRZ52_16100	COG0628	permease
NRZ52_16150	COG1131	(ABC) transporter
NRZ52_16175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRZ52_16180	COG0436	Aminotransferase
NRZ52_16210	COG2226	methyltransferase
NRZ52_16245	COG2814	Major facilitator Superfamily
NRZ52_16245	COG0477	Major facilitator Superfamily
NRZ52_16250	COG4533	DNA binding
NRZ52_16255	COG0789	Transcriptional regulator
NRZ52_16260	COG1664	Polymer-forming cytoskeletal
NRZ52_16270	COG2814	Major facilitator Superfamily
NRZ52_16310	COG1307	EDD domain protein, DegV family
NRZ52_16315	COG1522	sequence-specific DNA binding
NRZ52_16320	COG0531	amino acid
NRZ52_16325	COG1164	Oligoendopeptidase f
NRZ52_16360	COG0745	RESPONSE REGULATOR receiver
NRZ52_16365	COG5002	protein histidine kinase activity
NRZ52_16370	COG2936	dipeptidyl-peptidase activity
NRZ52_16420	COG4948	Mandelate Racemase Muconate Lactonizing
NRZ52_16430	COG4166	transmembrane transport
NRZ52_16435	COG0519	Catalyzes the synthesis of GMP from XMP
NRZ52_16440	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NRZ52_16455	COG0586	Pfam SNARE associated Golgi protein
NRZ52_16460	COG1078	dGTPase activity
NRZ52_16510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ52_16515	COG3938	Belongs to the proline racemase family
NRZ52_16525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRZ52_16530	COG1012	belongs to the aldehyde dehydrogenase family
NRZ52_16535	COG1115	amino acid carrier protein
NRZ52_16540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NRZ52_16555	COG3397	chitin binding
NRZ52_16575	COG4637	Psort location Cytoplasmic, score
NRZ52_16610	COG0514	ATP-dependent DNA helicase (RecQ)
NRZ52_16615	COG2105	PFAM AIG2 family protein
NRZ52_16630	COG3973	AAA domain
NRZ52_16675	COG0658	competence protein
NRZ52_16675	COG2333	competence protein COMEC
NRZ52_16685	COG2315	Protein conserved in bacteria
NRZ52_16690	COG2226	methyltransferase
NRZ52_16695	COG2205	protein histidine kinase activity
NRZ52_16715	COG1819	glycosyl
NRZ52_16720	COG3397	chitin binding
NRZ52_16725	COG2153	protein acetylation
NRZ52_16755	COG0517	IMP dehydrogenase activity
NRZ52_16755	COG4175	Glycine betaine
NRZ52_16760	COG4176	ABC-type proline glycine betaine transport system permease component
NRZ52_16800	COG0456	acetyltransferase
NRZ52_16800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NRZ52_16805	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_16815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NRZ52_16820	COG0022	dehydrogenase e1 component
NRZ52_16825	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRZ52_16830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRZ52_16845	COG1349	DNA-binding transcription factor activity
NRZ52_16865	COG3284	Transcriptional regulator
NRZ52_16900	COG1309	transcriptional regulator
NRZ52_16905	COG3844	kynureninase activity
NRZ52_16940	COG2959	enzyme of heme biosynthesis
NRZ52_16955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ52_16990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ52_16995	COG0697	spore germination
NRZ52_17005	COG0201	protein transport
NRZ52_17010	COG0346	lactoylglutathione lyase activity
NRZ52_17030	COG3227	Zinc metalloprotease (Elastase)
NRZ52_17035	COG1523	belongs to the glycosyl hydrolase 13 family
NRZ52_17085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ52_17125	COG0322	excinuclease ABC activity
NRZ52_17165	COG4667	esterase of the alpha-beta hydrolase superfamily
NRZ52_17185	COG3878	Protein conserved in bacteria
NRZ52_17230	COG2223	nitrite transmembrane transporter activity
NRZ52_17240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NRZ52_17255	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NRZ52_17275	COG0697	spore germination
NRZ52_17280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ52_17295	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ52_17350	COG0693	protein deglycase activity
NRZ52_17395	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_17405	COG0768	penicillin binding
NRZ52_17410	COG0671	phosphoesterase, PA-phosphatase related
NRZ52_17415	COG0604	alcohol dehydrogenase
NRZ52_17420	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NRZ52_17430	COG2205	protein histidine kinase activity
NRZ52_17455	COG1794	racemase activity, acting on amino acids and derivatives
NRZ52_17460	COG1819	glycosyl
NRZ52_17465	COG0768	penicillin binding
NRZ52_17470	COG5002	protein histidine kinase activity
NRZ52_17475	COG0561	phosphatase activity
NRZ52_17510	COG2124	cytochrome p450
NRZ52_17580	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NRZ52_17590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ52_17595	COG0460	homoserine dehydrogenase
NRZ52_17615	COG0577	efflux transmembrane transporter activity
NRZ52_17620	COG1136	(ABC) transporter
NRZ52_17625	COG0488	(ABC) transporter
NRZ52_17635	COG2205	protein histidine kinase activity
NRZ52_17640	COG0745	RESPONSE REGULATOR receiver
NRZ52_17650	COG3773	Cell wall hydrolase
NRZ52_17655	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
NRZ52_17665	COG3386	PFAM SMP-30 Gluconolaconase
NRZ52_17720	COG3227	Zinc metalloprotease (Elastase)
NRZ52_17735	COG2910	NAD(P)H-binding
NRZ52_17740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NRZ52_17765	COG1686	Belongs to the peptidase S11 family
NRZ52_17770	COG2318	DinB family
NRZ52_17775	COG0596	Alpha beta hydrolase
NRZ52_17780	COG0572	uridine kinase
NRZ52_17785	COG1247	-acetyltransferase
NRZ52_17795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRZ52_17800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NRZ52_17805	COG1024	Enoyl-CoA hydratase
NRZ52_17810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NRZ52_17815	COG0511	ligase activity, forming carbon-carbon bonds
NRZ52_17820	COG0439	Biotin carboxylase
NRZ52_17825	COG1960	acyl-CoA dehydrogenase activity
NRZ52_17850	COG1309	transcriptional regulator
NRZ52_17860	COG1131	(ABC) transporter
NRZ52_17875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ52_17875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ52_17910	COG0531	amino acid
NRZ52_17960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NRZ52_17960	COG2755	lipolytic protein G-D-S-L family
NRZ52_17975	COG0768	penicillin binding
NRZ52_17980	COG0768	penicillin binding
NRZ52_17990	COG1595	DNA-templated transcription, initiation
NRZ52_18000	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRZ52_18030	COG1846	Transcriptional regulator
NRZ52_18035	COG3961	Belongs to the TPP enzyme family
NRZ52_18040	COG2226	methyltransferase
NRZ52_18050	COG0500	methyltransferase
NRZ52_18050	COG3615	Tellurite resistance protein tehB
NRZ52_18055	COG1136	(ABC) transporter
NRZ52_18055	COG0577	efflux transmembrane transporter activity
NRZ52_18070	COG1309	transcriptional regulator
NRZ52_18100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ52_18135	COG2971	BadF BadG BcrA BcrD
NRZ52_18160	COG1649	PFAM Uncharacterised BCR, COG1649
NRZ52_18190	COG1595	DNA-templated transcription, initiation
NRZ52_18195	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
NRZ52_18205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRZ52_18240	COG1396	sequence-specific DNA binding
NRZ52_18255	COG1132	(ABC) transporter
NRZ52_18260	COG1132	(ABC) transporter
NRZ52_18275	COG2258	MOSC domain
NRZ52_18280	COG0583	DNA-binding transcription factor activity
NRZ52_18295	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRZ52_18300	COG0583	DNA-binding transcription factor activity
NRZ52_18305	COG2814	Major facilitator Superfamily
NRZ52_18310	COG1846	Transcriptional regulator
NRZ52_18335	COG1278	Cold shock
NRZ52_18345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ52_18360	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NRZ52_18390	COG1247	-acetyltransferase
NRZ52_18420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ52_18475	COG0028	Belongs to the TPP enzyme family
NRZ52_18490	COG2814	Major facilitator Superfamily
NRZ52_18500	COG1136	(ABC) transporter
NRZ52_18510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NRZ52_18515	COG1187	pseudouridine synthase activity
NRZ52_18520	COG2329	Antibiotic biosynthesis monooxygenase
NRZ52_18535	COG1115	amino acid carrier protein
NRZ52_18545	COG2318	DinB family
NRZ52_18580	COG2814	Major facilitator Superfamily
NRZ52_18585	COG3251	PFAM MbtH domain protein
NRZ52_18590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ52_18595	COG1535	isochorismatase
NRZ52_18595	COG3433	isochorismatase activity
NRZ52_18600	COG1021	2,3-dihydroxybenzoate-AMP ligase
NRZ52_18605	COG1169	isochorismate synthase
NRZ52_18610	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_18615	COG2223	nitrite transmembrane transporter activity
NRZ52_18645	COG0420	3'-5' exonuclease activity
NRZ52_18660	COG1024	Enoyl-CoA hydratase
NRZ52_18665	COG1280	lysine exporter protein (LysE YggA)
NRZ52_18675	COG2084	Dehydrogenase
NRZ52_18680	COG1960	acyl-CoA dehydrogenase activity
NRZ52_18685	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NRZ52_18690	COG2079	MmgE PrpD family protein
NRZ52_18695	COG0372	Belongs to the citrate synthase family
NRZ52_18705	COG2814	Major facilitator Superfamily
NRZ52_18715	COG4499	WXG100 protein secretion system (Wss), protein YukC
NRZ52_18715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ52_18760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ52_18790	COG1595	DNA-templated transcription, initiation
NRZ52_18825	COG3728	DNA packaging
NRZ52_18825	COG5484	DNA packaging
NRZ52_18835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ52_18840	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NRZ52_18845	COG0671	phosphoesterase, PA-phosphatase related
NRZ52_18850	COG4326	sporulation control protein
NRZ52_18855	COG0515	serine threonine protein kinase
NRZ52_18855	COG4991	sh3 domain protein
NRZ52_18855	COG3064	Membrane
NRZ52_18890	COG1509	lysine 2,3-aminomutase activity
NRZ52_18895	COG3829	transcription factor binding
NRZ52_18900	COG0456	acetyltransferase
NRZ52_18905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRZ52_18910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NRZ52_18915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NRZ52_18920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NRZ52_18935	COG5506	Protein of unknown function (DUF1694)
NRZ52_18940	COG1012	belongs to the aldehyde dehydrogenase family
NRZ52_18945	COG1253	flavin adenine dinucleotide binding
NRZ52_18980	COG1174	glycine betaine transport
NRZ52_18985	COG0517	IMP dehydrogenase activity
NRZ52_18985	COG1125	glycine betaine transport
NRZ52_19045	COG1064	alcohol dehydrogenase
NRZ52_19055	COG2197	response regulator
NRZ52_19060	COG2203	Gaf domain
NRZ52_19060	COG4585	Histidine kinase
NRZ52_19065	COG0668	transmembrane transport
NRZ52_19070	COG0071	Belongs to the small heat shock protein (HSP20) family
NRZ52_19075	COG1051	belongs to the nudix hydrolase family
NRZ52_19080	COG1335	isochorismatase
NRZ52_19095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRZ52_19100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ52_19120	COG0367	asparagine synthase
NRZ52_19125	COG0071	Belongs to the small heat shock protein (HSP20) family
NRZ52_19130	COG1999	signal sequence binding
NRZ52_19135	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NRZ52_19140	COG1307	EDD domain protein, DegV family
NRZ52_19150	COG0805	protein transport
NRZ52_19160	COG1272	protein, Hemolysin III
NRZ52_19165	COG0204	Acyl-transferase
NRZ52_19175	COG0768	penicillin binding
NRZ52_19195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NRZ52_19215	COG0546	phosphoglycolate phosphatase activity
NRZ52_19225	COG4473	ABC transporter
NRZ52_19230	COG1131	(ABC) transporter
NRZ52_19240	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NRZ52_19245	COG0456	acetyltransferase
NRZ52_19255	COG1794	racemase activity, acting on amino acids and derivatives
NRZ52_19260	COG1454	alcohol dehydrogenase
NRZ52_19265	COG2610	gluconate transmembrane transporter activity
NRZ52_19290	COG0733	neurotransmitter:sodium symporter activity
NRZ52_19350	COG1674	ftsk spoiiie
NRZ52_19370	COG0017	Asparaginyl-tRNA synthetase
NRZ52_19410	COG2521	methyltransferase
NRZ52_19410	COG2136	Putative SAM-dependent methyltransferase
NRZ52_19425	COG1413	lyase activity
NRZ52_19430	COG0629	single-stranded DNA binding
NRZ52_19445	COG0488	(ABC) transporter
NRZ52_19450	COG1418	mRNA catabolic process
NRZ52_19485	COG2359	stage V sporulation protein S
NRZ52_19520	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
NRZ52_19525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRZ52_19530	COG2146	nitrite reductase [NAD(P)H] activity
NRZ52_19535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRZ52_19535	COG1587	Uroporphyrinogen-III synthase
NRZ52_19545	COG1648	precorrin-2 dehydrogenase activity
NRZ52_19565	COG2223	nitrite transmembrane transporter activity
NRZ52_19575	COG0314	molybdopterin synthase activity
NRZ52_19580	COG0303	'Molybdopterin
NRZ52_19585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ52_19590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NRZ52_19595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRZ52_19600	COG2181	nitrate reductase activity
NRZ52_19605	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NRZ52_19610	COG1140	nitrate reductase beta subunit
NRZ52_19615	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NRZ52_19630	COG0714	Associated with various cellular activities
NRZ52_19635	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NRZ52_19645	COG0386	Belongs to the glutathione peroxidase family
NRZ52_19655	COG0426	domain, Protein
NRZ52_19655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NRZ52_19675	COG1595	DNA-templated transcription, initiation
NRZ52_19680	COG0604	alcohol dehydrogenase
NRZ52_19690	COG0346	lactoylglutathione lyase activity
NRZ52_19715	COG2226	methyltransferase
NRZ52_19740	COG3874	Sporulation protein YtfJ
NRZ52_19815	COG0456	acetyltransferase
NRZ52_19845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ52_19850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ52_19855	COG1819	glycosyl
NRZ52_19870	COG4106	trans-aconitate 2-methyltransferase activity
NRZ52_19875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRZ52_19885	COG0561	phosphatase activity
NRZ52_19915	COG3971	2-oxopent-4-enoate hydratase activity
NRZ52_19925	COG0251	oxidation-reduction process
NRZ52_19940	COG0196	riboflavin kinase activity
NRZ52_19950	COG2368	4-hydroxyphenylacetate
NRZ52_19965	COG2211	Major facilitator Superfamily
NRZ52_19970	COG0154	amidase activity
NRZ52_19980	COG1876	peptidase activity
NRZ52_19990	COG0860	N-Acetylmuramoyl-L-alanine amidase
NRZ52_20010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ52_20015	COG1114	Component of the transport system for branched-chain amino acids
NRZ52_20030	COG1253	flavin adenine dinucleotide binding
NRZ52_20035	COG2839	Protein conserved in bacteria
NRZ52_20040	COG0702	epimerase
NRZ52_20055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ52_20065	COG1607	acyl-coa hydrolase
NRZ52_20070	COG3689	TIGRFAM TIGR03943 family protein
NRZ52_20075	COG0701	Predicted permease
NRZ52_20085	COG2244	polysaccharide biosynthetic process
NRZ52_20090	COG0586	Pfam SNARE associated Golgi protein
NRZ52_20095	COG1051	belongs to the nudix hydrolase family
NRZ52_20100	COG5337	Spore coat protein CotH
NRZ52_20110	COG0406	alpha-ribazole phosphatase activity
NRZ52_20125	COG4166	transmembrane transport
NRZ52_20135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NRZ52_20145	COG0702	epimerase
NRZ52_20155	COG3443	Belongs to the bacterial solute-binding protein 9 family
NRZ52_20155	COG0803	Belongs to the bacterial solute-binding protein 9 family
NRZ52_20160	COG0456	acetyltransferase
NRZ52_20165	COG0523	cobalamin synthesis protein
NRZ52_20170	COG4989	oxidoreductase activity
NRZ52_20175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ52_20180	COG1231	oxidoreductase activity
NRZ52_20190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NRZ52_20205	COG0783	Belongs to the Dps family
NRZ52_20210	COG3949	Membrane
NRZ52_20255	COG0667	Aldo Keto reductase
NRZ52_20260	COG0640	Transcriptional regulator
NRZ52_20265	COG1404	Belongs to the peptidase S8 family
NRZ52_20270	COG2002	toxin-antitoxin pair type II binding
NRZ52_20275	COG0577	efflux transmembrane transporter activity
NRZ52_20310	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRZ52_20320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ52_20325	COG1279	arginine transmembrane transporter activity
NRZ52_20330	COG2814	Major facilitator Superfamily
NRZ52_20340	COG1247	-acetyltransferase
NRZ52_20345	COG1285	pathogenesis
NRZ52_20365	COG1316	TRANSCRIPTIONal
NRZ52_20390	COG0460	homoserine dehydrogenase
NRZ52_20405	COG5658	integral membrane protein
NRZ52_20420	COG4122	O-methyltransferase activity
NRZ52_20425	COG0300	oxidoreductase activity
NRZ52_20430	COG5002	protein histidine kinase activity
NRZ52_20435	COG0745	RESPONSE REGULATOR receiver
NRZ52_20440	COG1132	(ABC) transporter
NRZ52_20450	COG0791	NLP P60 protein
NRZ52_20450	COG1388	LysM domain
NRZ52_20465	COG1686	Belongs to the peptidase S11 family
NRZ52_20505	COG1216	Glycosyl transferase, family 2
NRZ52_20515	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NRZ52_20520	COG4988	ABC transporter
NRZ52_20525	COG1294	oxidase, subunit
NRZ52_20530	COG1271	oxidase subunit
NRZ52_20550	COG1942	4-Oxalocrotonate Tautomerase
NRZ52_20590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ52_20595	COG2030	dehydratase
NRZ52_20600	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ52_20615	COG0523	cobalamin synthesis protein
NRZ52_20620	COG1231	oxidoreductase activity
NRZ52_20630	COG0628	permease
NRZ52_20645	COG0778	Nitroreductase
NRZ52_20650	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NRZ52_20655	COG1959	2 iron, 2 sulfur cluster binding
NRZ52_20660	COG0583	DNA-binding transcription factor activity
NRZ52_20665	COG0697	spore germination
NRZ52_20670	COG4549	nuclear export factor GLE1
NRZ52_20675	COG1276	copper resistance
NRZ52_20675	COG2372	response to copper ion
NRZ52_20685	COG1114	Component of the transport system for branched-chain amino acids
NRZ52_20715	COG3344	reverse transcriptase
NRZ52_20735	COG0006	proline dipeptidase activity
NRZ52_20745	COG4846	Membrane protein involved in cytochrome C biogenesis
NRZ52_20755	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NRZ52_20760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ52_20770	COG2390	Transcriptional regulator
NRZ52_20795	COG0531	amino acid
NRZ52_20805	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NRZ52_20820	COG1914	H( )-stimulated, divalent metal cation uptake system
NRZ52_20840	COG0745	RESPONSE REGULATOR receiver
NRZ52_20845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ52_20850	COG0535	radical SAM domain protein
NRZ52_20865	COG4166	transmembrane transport
NRZ52_20885	COG0427	acetyl-CoA hydrolase
NRZ52_20890	COG3279	Response regulator of the LytR AlgR family
NRZ52_20900	COG3384	dioxygenase
NRZ52_20905	COG2814	Major facilitator Superfamily
NRZ52_20930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NRZ52_20950	COG0028	Belongs to the TPP enzyme family
NRZ52_20955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRZ52_20965	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRZ52_20980	COG2323	membrane
NRZ52_20985	COG5566	PFAM Mor transcription activator
NRZ52_20995	COG0733	neurotransmitter:sodium symporter activity
NRZ52_21000	COG2244	polysaccharide biosynthetic process
NRZ52_21015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NRZ52_21020	COG2223	nitrite transmembrane transporter activity
NRZ52_21025	COG4166	transmembrane transport
NRZ52_21030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NRZ52_21040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ52_21045	COG0477	Major facilitator Superfamily
NRZ52_21055	COG1695	Transcriptional regulator
NRZ52_21070	COG1105	Belongs to the carbohydrate kinase PfkB family
NRZ52_21085	COG2222	sugar isomerase
NRZ52_21090	COG2188	Transcriptional regulator
NRZ52_21100	COG0395	ABC-type sugar transport system, permease component
NRZ52_21105	COG1175	transmembrane transport
NRZ52_21115	COG2508	Transcriptional regulator
NRZ52_21120	COG3842	ATPase activity
NRZ52_21145	COG0860	N-Acetylmuramoyl-L-alanine amidase
NRZ52_21150	COG1051	belongs to the nudix hydrolase family
NRZ52_21200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NRZ52_21205	COG0784	Response regulator, receiver
NRZ52_21210	COG4191	Histidine kinase
NRZ52_21215	COG0281	malic enzyme
NRZ52_21220	COG1027	Aspartate ammonia-lyase
NRZ52_21230	COG0528	UMP kinase activity
NRZ52_21235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ52_21250	COG1131	(ABC) transporter
NRZ52_21285	COG2733	membrane
NRZ52_21315	COG0785	Cytochrome C biogenesis protein
NRZ52_21335	COG3340	Belongs to the peptidase S51 family
NRZ52_21340	COG0534	Mate efflux family protein
NRZ52_21355	COG0114	fumarate hydratase activity
NRZ52_21365	COG1757	Na H antiporter
NRZ52_21370	COG1216	Glycosyl transferase, family 2
NRZ52_21370	COG0438	transferase activity, transferring glycosyl groups
NRZ52_21375	COG0697	spore germination
NRZ52_21380	COG1802	Transcriptional regulator
NRZ52_21410	COG0367	asparagine synthase
NRZ52_21420	COG1846	Transcriptional regulator
NRZ52_21440	COG0406	alpha-ribazole phosphatase activity
NRZ52_21455	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_21470	COG1234	tRNA 3'-trailer cleavage
NRZ52_21485	COG3842	ATPase activity
NRZ52_21490	COG0583	DNA-binding transcription factor activity
NRZ52_21515	COG2329	Antibiotic biosynthesis monooxygenase
NRZ52_21535	COG1309	transcriptional regulator
NRZ52_21560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NRZ52_21565	COG4786	Flagellar basal body rod
NRZ52_21570	COG1419	protein localization to endoplasmic reticulum
NRZ52_21575	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NRZ52_21580	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NRZ52_21590	COG1987	bacterial-type flagellum assembly
NRZ52_21595	COG1338	Plays a role in the flagellum-specific transport system
NRZ52_21605	COG1776	CheC inhibitor of MCP methylation
NRZ52_21605	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ52_21610	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ52_21620	COG0741	lytic transglycosylase activity
NRZ52_21625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ52_21630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ52_21640	COG0784	Response regulator, receiver
NRZ52_21640	COG0835	chemotaxis
NRZ52_21675	COG1157	protein secretion by the type III secretion system
NRZ52_21685	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ52_21690	COG1766	The M ring may be actively involved in energy transduction
NRZ52_21700	COG1558	bacterial-type flagellum-dependent cell motility
NRZ52_21705	COG1815	bacterial-type flagellum-dependent cell motility
NRZ52_21720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NRZ52_21725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ52_21730	COG1256	bacterial-type flagellum assembly
NRZ52_21750	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NRZ52_21765	COG1776	CheC inhibitor of MCP methylation
NRZ52_21765	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ52_21770	COG0643	Histidine kinase
NRZ52_21770	COG2198	Histidine kinase
NRZ52_21775	COG2201	protein-glutamate methylesterase activity
NRZ52_21780	COG1360	Flagellar Motor Protein
NRZ52_21785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ52_21795	COG1923	regulation of RNA biosynthetic process
NRZ52_21815	COG2814	Major facilitator Superfamily
NRZ52_21825	COG2814	Major facilitator Superfamily
NRZ52_21860	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NRZ52_21865	COG2323	membrane
NRZ52_21875	COG0789	Transcriptional regulator
NRZ52_21875	COG4978	Transcriptional regulator
NRZ52_21880	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NRZ52_21885	COG0475	glutathione-regulated potassium exporter activity
NRZ52_21895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NRZ52_21900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ52_21905	COG3162	membrane
NRZ52_21920	COG1280	lysine exporter protein (LysE YggA)
NRZ52_21925	COG3403	YqcI/YcgG family
NRZ52_21960	COG0328	RNA-DNA hybrid ribonuclease activity
NRZ52_21980	COG0454	-acetyltransferase
NRZ52_22050	COG5632	N-Acetylmuramoyl-L-alanine amidase
NRZ52_22125	COG4626	Terminase
NRZ52_22125	COG1802	Transcriptional regulator
NRZ52_22210	COG3646	Phage regulatory protein
NRZ52_22210	COG3645	SOS response
NRZ52_22230	COG3800	Transcriptional regulator
NRZ52_22230	COG1396	sequence-specific DNA binding
NRZ52_22255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ52_22270	COG0754	glutathionylspermidine amidase activity
NRZ52_22305	COG0456	acetyltransferase
NRZ52_22315	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NRZ52_22325	COG2311	Membrane
NRZ52_22330	COG2233	PERMEase
NRZ52_22340	COG0024	Methionine aminopeptidase
NRZ52_22350	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NRZ52_22355	COG1199	ATP-dependent helicase activity
NRZ52_22365	COG0116	Belongs to the methyltransferase superfamily
NRZ52_22425	COG4499	WXG100 protein secretion system (Wss), protein YukC
NRZ52_22425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ52_22435	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NRZ52_22440	COG3935	DnaD domain protein
NRZ52_22460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NRZ52_22460	COG1199	ATP-dependent helicase activity
NRZ52_22495	COG0438	transferase activity, transferring glycosyl groups
NRZ52_22500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NRZ52_22515	COG1694	Mazg nucleotide pyrophosphohydrolase
NRZ52_22520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ52_22530	COG2738	Putative neutral zinc metallopeptidase
NRZ52_22545	COG4347	Protein of unknown function (DUF1405)
NRZ52_22550	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NRZ52_22550	COG2010	Cytochrome c
NRZ52_22555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NRZ52_22575	COG0457	Tetratricopeptide repeat
NRZ52_22580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NRZ52_22600	COG0142	geranyltranstransferase activity
NRZ52_22610	COG0142	geranyltranstransferase activity
NRZ52_22625	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NRZ52_22700	COG0492	ferredoxin-NADP+ reductase activity
NRZ52_22720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NRZ52_22725	COG4862	establishment of competence for transformation
NRZ52_22735	COG1408	metallophosphoesterase
NRZ52_22745	COG1266	CAAX protease self-immunity
NRZ52_22750	COG0514	ATP-dependent DNA helicase (RecQ)
NRZ52_22760	COG1141	Ferredoxin
NRZ52_22765	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NRZ52_22780	COG4942	peptidase
NRZ52_22785	COG2096	Adenosyltransferase
NRZ52_22790	COG5002	protein histidine kinase activity
NRZ52_22795	COG0745	RESPONSE REGULATOR receiver
NRZ52_22800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ52_22805	COG1333	cytochrome c biogenesis protein
NRZ52_22815	COG1187	pseudouridine synthase activity
NRZ52_22820	COG0700	Nucleoside recognition
NRZ52_22825	COG2715	membrane protein required for spore maturation
NRZ52_22830	COG1686	Belongs to the peptidase S11 family
NRZ52_22835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NRZ52_22850	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NRZ52_22850	COG0392	lysyltransferase activity
NRZ52_22865	COG5002	protein histidine kinase activity
NRZ52_22870	COG0582	viral genome integration into host DNA
NRZ52_22880	COG1801	Protein of unknown function DUF72
NRZ52_22885	COG3852	Histidine kinase
NRZ52_22900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ52_22905	COG1392	Phosphate transport regulator
NRZ52_22910	COG0306	phosphate transporter
NRZ52_22915	COG0730	response to heat
NRZ52_22955	COG2226	methyltransferase
NRZ52_22965	COG1114	Component of the transport system for branched-chain amino acids
NRZ52_22975	COG2197	response regulator
NRZ52_22980	COG4585	Histidine kinase
NRZ52_22985	COG4758	membrane
NRZ52_23000	COG1757	Na H antiporter
NRZ52_23025	COG0733	neurotransmitter:sodium symporter activity
NRZ52_23030	COG1648	precorrin-2 dehydrogenase activity
NRZ52_23050	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRZ52_23055	COG0529	Catalyzes the synthesis of activated sulfate
NRZ52_23075	COG0019	diaminopimelate decarboxylase activity
NRZ52_23085	COG1368	sulfuric ester hydrolase activity
NRZ52_23090	COG1183	phosphatidylcholine synthase activity
NRZ52_23105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NRZ52_23180	COG0440	acetolactate synthase activity
NRZ52_23185	COG0028	Belongs to the TPP enzyme family
NRZ52_23190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRZ52_23210	COG3874	Sporulation protein YtfJ
NRZ52_23215	COG4709	membrane
NRZ52_23220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ52_23225	COG1301	dicarboxylic acid transport
NRZ52_23235	COG1846	Transcriptional regulator
NRZ52_23255	COG0534	Mate efflux family protein
NRZ52_23275	COG3173	Aminoglycoside phosphotransferase
NRZ52_23290	COG0716	FMN binding
NRZ52_23315	COG1696	Membrane protein involved in D-alanine export
NRZ52_23325	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NRZ52_23330	COG2070	2-Nitropropane dioxygenase
NRZ52_23335	COG1619	proteins homologs of microcin C7 resistance protein MccF
NRZ52_23345	COG1335	isochorismatase
NRZ52_23355	COG1522	sequence-specific DNA binding
NRZ52_23365	COG1266	CAAX protease self-immunity
NRZ52_23370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NRZ52_23375	COG1131	(ABC) transporter
NRZ52_23385	COG1131	(ABC) transporter
NRZ52_23390	COG1725	Transcriptional regulator
NRZ52_23395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRZ52_23410	COG1780	Probably involved in ribonucleotide reductase function
NRZ52_23440	COG4873	Protein conserved in bacteria
NRZ52_23455	COG0720	synthase
NRZ52_23465	COG5002	protein histidine kinase activity
NRZ52_23475	COG2318	DinB family
NRZ52_23485	COG1846	Transcriptional regulator
NRZ52_23490	COG3852	Histidine kinase
NRZ52_23500	COG2861	carbohydrate metabolic process
NRZ52_23510	COG0235	Class ii aldolase
NRZ52_23520	COG1349	DNA-binding transcription factor activity
NRZ52_23545	COG3842	ATPase activity
NRZ52_23550	COG1840	ABC-type Fe3 transport system, periplasmic component
NRZ52_23565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ52_23575	COG3243	poly(R)-hydroxyalkanoic acid synthase
NRZ52_23580	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_23600	COG2030	dehydratase
NRZ52_23610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ52_23615	COG0861	Integral membrane protein TerC family
NRZ52_23620	COG2116	formate transmembrane transporter activity
NRZ52_23630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NRZ52_23650	COG2186	Transcriptional regulator
NRZ52_23655	COG5002	protein histidine kinase activity
NRZ52_23660	COG0745	RESPONSE REGULATOR receiver
NRZ52_23670	COG3835	regulator
NRZ52_23675	COG0277	FAD linked oxidase domain protein
NRZ52_23680	COG0247	lactate metabolic process
NRZ52_23685	COG2340	Cysteine-rich secretory protein family
NRZ52_23695	COG0564	pseudouridine synthase activity
NRZ52_23705	COG2409	Drug exporters of the RND superfamily
NRZ52_23715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NRZ52_23720	COG1177	transmembrane transport
NRZ52_23725	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRZ52_23735	COG1012	belongs to the aldehyde dehydrogenase family
NRZ52_23750	COG1396	sequence-specific DNA binding
NRZ52_23770	COG0681	Belongs to the peptidase S26 family
NRZ52_23775	COG1686	Belongs to the peptidase S11 family
NRZ52_23850	COG1476	TRANSCRIPTIONal
NRZ52_23860	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRZ52_23915	COG5634	Uncharacterized conserved protein (DUF2278)
NRZ52_23920	COG1620	l-lactate permease
NRZ52_23955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRZ52_23955	COG0512	Glutamine amidotransferase of anthranilate synthase
NRZ52_23965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ52_23970	COG5492	domain, Protein
NRZ52_23985	COG2382	esterase
NRZ52_23995	COG2153	protein acetylation
NRZ52_24040	COG1091	dTDP-4-dehydrorhamnose reductase activity
NRZ52_24055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NRZ52_24075	COG0457	Tetratricopeptide repeat
NRZ52_24075	COG0463	Glycosyl transferase, family 2
NRZ52_24105	COG0463	Glycosyl transferase, family 2
NRZ52_24105	COG1216	Glycosyl transferase, family 2
NRZ52_24110	COG0772	Belongs to the SEDS family
NRZ52_24125	COG0564	pseudouridine synthase activity
NRZ52_24135	COG2357	RelA SpoT domain protein
NRZ52_24145	COG4116	CYTH
NRZ52_24150	COG2346	COG2346, Truncated hemoglobins
NRZ52_24165	COG1164	Oligoendopeptidase f
NRZ52_24175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ52_24180	COG4862	establishment of competence for transformation
NRZ52_24185	COG0861	Integral membrane protein TerC family
NRZ52_24200	COG4166	transmembrane transport
NRZ52_24205	COG0534	Mate efflux family protein
NRZ52_24210	COG4608	Belongs to the ABC transporter superfamily
NRZ52_24215	COG0444	Belongs to the ABC transporter superfamily
NRZ52_24220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ52_24225	COG0601	transmembrane transport
NRZ52_24230	COG4166	transmembrane transport
NRZ52_24240	COG0180	Tryptophanyl-tRNA synthetase
NRZ52_24250	COG5504	Zn-dependent protease
NRZ52_24255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRZ52_24260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ52_24275	COG2267	carboxylic ester hydrolase activity
NRZ52_24295	COG0561	phosphatase activity
NRZ52_24310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ52_24320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ52_24325	COG2996	Protein conserved in bacteria
NRZ52_24345	COG0004	ammonium transporteR
NRZ52_24350	COG0753	catalase activity
NRZ52_24360	COG0367	asparagine synthase
NRZ52_24385	COG0179	Fumarylacetoacetate (FAA) hydrolase
NRZ52_24445	COG0398	Pfam SNARE associated Golgi protein
NRZ52_24450	COG4903	ComK protein
NRZ52_24465	COG1278	Cold shock
NRZ52_24475	COG2224	Isocitrate lyase
NRZ52_24480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NRZ52_24500	COG0697	spore germination
NRZ52_24505	COG0840	transmembrane signaling receptor activity
NRZ52_24510	COG0501	Belongs to the peptidase M48B family
NRZ52_24535	COG0745	RESPONSE REGULATOR receiver
NRZ52_24540	COG2205	protein histidine kinase activity
NRZ52_24555	COG2207	Transcriptional regulator
NRZ52_24555	COG3708	Transcriptional regulator
NRZ52_24560	COG1595	DNA-templated transcription, initiation
NRZ52_24570	COG0477	Major facilitator Superfamily
NRZ52_24580	COG1078	dGTPase activity
NRZ52_24585	COG1408	metallophosphoesterase
NRZ52_24605	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ52_24615	COG0095	Lipoate-protein ligase
NRZ52_24620	COG1234	tRNA 3'-trailer cleavage
NRZ52_24630	COG1609	Transcriptional regulator
NRZ52_24635	COG2378	regulation of single-species biofilm formation
NRZ52_24665	COG1511	domain protein
NRZ52_24670	COG1309	transcriptional regulator
NRZ52_24705	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NRZ52_24720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ52_24725	COG2329	Antibiotic biosynthesis monooxygenase
NRZ52_24730	COG3428	Bacterial PH domain
NRZ52_24735	COG3402	PFAM membrane-flanked domain
NRZ52_24755	COG3428	Bacterial PH domain
NRZ52_24760	COG3402	PFAM membrane-flanked domain
NRZ52_24770	COG1309	transcriptional regulator
NRZ52_24860	COG4473	ABC transporter
NRZ52_24865	COG1131	(ABC) transporter
NRZ52_24870	COG0537	adenosine 5'-monophosphoramidase activity
NRZ52_24875	COG4980	gas vesicle protein
NRZ52_24895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ52_24900	COG3973	AAA domain
NRZ52_24910	COG2409	Drug exporters of the RND superfamily
NRZ52_24910	COG1033	growth of symbiont in host cell
NRZ52_24920	COG0477	Major facilitator Superfamily
NRZ52_24925	COG0477	Major facilitator Superfamily
NRZ52_24940	COG0772	Belongs to the SEDS family
NRZ52_24960	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NRZ52_24970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRZ52_24975	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NRZ52_25000	COG2267	carboxylic ester hydrolase activity
NRZ52_25010	COG0457	Tetratricopeptide repeat
NRZ52_25020	COG0346	lactoylglutathione lyase activity
NRZ52_25025	COG0346	lactoylglutathione lyase activity
NRZ52_25070	COG5444	nuclease activity
NRZ52_25250	COG3331	DNA recombination
NRZ52_25320	COG3646	Phage regulatory protein
NRZ52_25350	COG4974	Belongs to the 'phage' integrase family
NRZ52_25360	COG4717	serine-type aminopeptidase activity
NRZ52_25365	COG0420	3'-5' exonuclease activity
NRZ52_25430	COG2205	protein histidine kinase activity
NRZ52_25430	COG2198	Histidine kinase
NRZ52_25430	COG0784	Response regulator, receiver
NRZ52_25435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NRZ52_25440	COG2208	phosphoserine phosphatase activity
NRZ52_25450	COG1191	sigma factor activity
NRZ52_25475	COG3237	CsbD-like
NRZ52_25545	COG0482	sulfurtransferase activity
NRZ52_25595	COG2376	Dihydroxyacetone kinase
NRZ52_25605	COG2376	Dihydroxyacetone kinase
NRZ52_25625	COG1183	phosphatidylcholine synthase activity
NRZ52_25635	COG2723	6-phospho-beta-galactosidase activity
NRZ52_25640	COG1263	PTS System
NRZ52_25640	COG2190	(PTS) system
NRZ52_25640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ52_25645	COG3711	transcriptional antiterminator
NRZ52_25655	COG1476	TRANSCRIPTIONal
NRZ52_25670	COG1309	transcriptional regulator
NRZ52_25675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRZ52_25675	COG3320	Male sterility
NRZ52_25740	COG0305	Participates in initiation and elongation during chromosome replication
NRZ52_25765	COG0789	Transcriptional regulator
NRZ52_25765	COG4978	Transcriptional regulator
NRZ52_25810	COG3181	Tripartite tricarboxylate transporter family receptor
NRZ52_25815	COG4565	transcriptional regulatory protein
NRZ52_25820	COG3290	protein histidine kinase activity
NRZ52_25825	COG0477	Major facilitator Superfamily
NRZ52_25860	COG1363	Peptidase, m42
NRZ52_25880	COG1024	Enoyl-CoA hydratase
NRZ52_25895	COG1696	Membrane protein involved in D-alanine export
NRZ52_25910	COG4196	transglutaminase domain protein
NRZ52_25915	COG0860	N-Acetylmuramoyl-L-alanine amidase
NRZ52_25925	COG2244	polysaccharide biosynthetic process
NRZ52_25930	COG0653	protein targeting
NRZ52_25945	COG0659	secondary active sulfate transmembrane transporter activity
NRZ52_25970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRZ52_25975	COG5632	N-Acetylmuramoyl-L-alanine amidase
NRZ52_25975	COG3409	Peptidoglycan-binding domain 1 protein
NRZ52_25980	COG0561	phosphatase activity
NRZ52_25990	COG3527	Alpha-acetolactate decarboxylase
NRZ52_25995	COG0028	Belongs to the TPP enzyme family
NRZ52_26035	COG2197	response regulator
NRZ52_26040	COG4585	Histidine kinase
NRZ52_26070	COG0189	ligase activity
NRZ52_26085	COG1126	abc transporter atp-binding protein
NRZ52_26090	COG0765	amino acid transport
NRZ52_26095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ52_26100	COG1132	(ABC) transporter
NRZ52_26105	COG1132	(ABC) transporter
NRZ52_26120	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NRZ52_26125	COG0531	amino acid
NRZ52_26135	COG0753	catalase activity
NRZ52_26140	COG0693	protein deglycase activity
NRZ52_26150	COG2211	Major facilitator Superfamily
NRZ52_26155	COG4533	DNA binding
NRZ52_26160	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRZ52_26170	COG1733	regulation of RNA biosynthetic process
NRZ52_26180	COG1063	alcohol dehydrogenase
NRZ52_26190	COG2124	cytochrome p450
NRZ52_26195	COG1309	transcriptional regulator
NRZ52_26205	COG0657	acetylesterase activity
NRZ52_26210	COG0477	Major facilitator Superfamily
NRZ52_26215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRZ52_26220	COG1846	Transcriptional regulator
NRZ52_26230	COG2814	Major facilitator Superfamily
NRZ52_26235	COG1309	transcriptional regulator
NRZ52_26240	COG2076	Multidrug Resistance protein
NRZ52_26255	COG1522	sequence-specific DNA binding
NRZ52_26275	COG2259	Doxx family
NRZ52_26285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ52_26285	COG1263	PTS System
NRZ52_26295	COG1737	Transcriptional regulator
NRZ52_26305	COG0475	glutathione-regulated potassium exporter activity
NRZ52_26310	COG0531	amino acid
NRZ52_26345	COG0586	Pfam SNARE associated Golgi protein
NRZ52_26380	COG3546	catalase activity
NRZ52_26385	COG1114	Component of the transport system for branched-chain amino acids
NRZ52_26390	COG0577	efflux transmembrane transporter activity
NRZ52_26405	COG5522	Integral membrane protein (intg_mem_TP0381)
NRZ52_26415	COG1136	(ABC) transporter
NRZ52_26420	COG0577	efflux transmembrane transporter activity
NRZ52_26425	COG3584	3D domain protein
NRZ52_26425	COG1388	LysM domain
NRZ52_26445	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NRZ52_26450	COG1447	Phosphotransferase system cellobiose-specific component IIA
NRZ52_26455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ52_26455	COG3711	transcriptional antiterminator
NRZ52_26465	COG2814	Major facilitator Superfamily
NRZ52_26470	COG1283	sodium-dependent phosphate transmembrane transporter activity
NRZ52_26475	COG0604	alcohol dehydrogenase
NRZ52_26480	COG1316	TRANSCRIPTIONal
NRZ52_26490	COG0730	response to heat
NRZ52_26495	COG2210	Belongs to the sulfur carrier protein TusA family
NRZ52_26505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ52_26515	COG0425	Belongs to the sulfur carrier protein TusA family
NRZ52_26520	COG0425	Belongs to the sulfur carrier protein TusA family
NRZ52_26525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ52_26525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ52_26530	COG0425	Belongs to the sulfur carrier protein TusA family
NRZ52_26530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ52_26535	COG1937	Protein conserved in bacteria
NRZ52_26540	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ52_26575	COG2719	SpoVR family
NRZ52_26580	COG0778	Nitroreductase
NRZ52_26620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ52_26635	COG1376	ErfK ybiS ycfS ynhG family protein
NRZ52_26640	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ52_26645	COG2252	PERMEase
NRZ52_26660	COG1846	Transcriptional regulator
NRZ52_26665	COG2814	Major facilitator Superfamily
NRZ52_26670	COG2205	protein histidine kinase activity
NRZ52_26710	COG0351	phosphomethylpyrimidine kinase
NRZ52_26715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ52_26725	COG2104	thiamine diphosphate biosynthetic process
NRZ52_26730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ52_26735	COG0352	thiamine-phosphate diphosphorylase activity
NRZ52_26740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NRZ52_26745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ52_26750	COG1116	anion transmembrane transporter activity
NRZ52_26755	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NRZ52_26775	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NRZ52_26895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ52_26905	COG0581	inorganic phosphate transmembrane transporter activity
NRZ52_26910	COG0573	inorganic phosphate transmembrane transporter activity
NRZ52_26915	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NRZ52_26920	COG1918	ferrous iron import across plasma membrane
NRZ52_26920	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NRZ52_26925	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NRZ52_26930	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NRZ52_26945	COG0531	amino acid
NRZ52_26955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ52_26970	COG4990	cell redox homeostasis
NRZ52_26975	COG0833	amino acid
NRZ52_26980	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NRZ52_26985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NRZ52_27000	COG0569	domain protein
NRZ52_27000	COG0475	glutathione-regulated potassium exporter activity
NRZ52_27010	COG2153	protein acetylation
NRZ52_27025	COG2252	PERMEase
NRZ52_27030	COG1113	amino acid transport
NRZ52_27045	COG2011	ABC-type metal ion transport system permease component
NRZ52_27050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NRZ52_27055	COG1960	acyl-CoA dehydrogenase activity
NRZ52_27060	COG1464	Belongs to the NlpA lipoprotein family
NRZ52_27065	COG1114	Component of the transport system for branched-chain amino acids
NRZ52_27070	COG3104	oligopeptide transport
NRZ52_27085	COG1476	TRANSCRIPTIONal
NRZ52_27090	COG3583	domain protein
NRZ52_27090	COG3584	3D domain protein
NRZ52_27095	COG0840	transmembrane signaling receptor activity
NRZ52_27125	COG3568	Endonuclease Exonuclease Phosphatase
NRZ52_27140	COG1063	alcohol dehydrogenase
NRZ52_27165	COG1879	ABC-type sugar transport system periplasmic component
NRZ52_27170	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRZ52_27185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ52_27190	COG1609	Transcriptional regulator
NRZ52_27195	COG0477	Major facilitator Superfamily
NRZ52_27200	COG1846	Transcriptional regulator
NRZ52_27205	COG2271	Major facilitator Superfamily
NRZ52_27215	COG4608	Belongs to the ABC transporter superfamily
NRZ52_27220	COG0601	transmembrane transport
NRZ52_27230	COG0747	negative chemotaxis
NRZ52_27240	COG0589	response to stress
NRZ52_27245	COG0659	secondary active sulfate transmembrane transporter activity
NRZ52_27260	COG5002	protein histidine kinase activity
NRZ52_27265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NRZ52_27270	COG2378	regulation of single-species biofilm formation
NRZ52_27280	COG1595	DNA-templated transcription, initiation
NRZ52_27295	COG0833	amino acid
NRZ52_27300	COG0765	amino acid transport
NRZ52_27305	COG0765	amino acid transport
NRZ52_27310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ52_27315	COG1126	abc transporter atp-binding protein
NRZ52_27320	COG1115	amino acid carrier protein
NRZ52_27325	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NRZ52_27335	COG0697	spore germination
NRZ52_27350	COG0366	Alpha amylase catalytic
NRZ52_27355	COG1263	PTS System
NRZ52_27355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ52_27360	COG2188	Transcriptional regulator
NRZ52_27365	COG0531	amino acid
NRZ52_27385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ52_27390	COG0714	Associated with various cellular activities
NRZ52_27395	COG4548	von Willebrand factor, type A
NRZ52_27405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NRZ52_27410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ52_27415	COG0156	8-amino-7-oxononanoate synthase activity
NRZ52_27420	COG2226	methyltransferase
NRZ52_27430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ52_27435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ52_27440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ52_27445	COG3104	oligopeptide transport
NRZ52_27460	COG1620	l-lactate permease
NRZ52_27465	COG1027	Aspartate ammonia-lyase
NRZ52_27470	COG1253	flavin adenine dinucleotide binding
NRZ52_27475	COG0346	lactoylglutathione lyase activity
NRZ52_27480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ52_27485	COG1316	TRANSCRIPTIONal
NRZ52_27490	COG2720	vancomycin resistance protein
NRZ52_27510	COG3227	Zinc metalloprotease (Elastase)
NRZ52_27525	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NRZ52_27530	COG2217	Heavy metal translocating P-type atpase
NRZ52_27535	COG0640	Transcriptional regulator
NRZ52_27540	COG0531	amino acid
NRZ52_27555	COG2427	Protein of unknown function (DUF1641)
NRZ52_27560	COG3383	formate dehydrogenase (NAD+) activity
NRZ52_27565	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRZ52_27570	COG0456	acetyltransferase
NRZ52_27570	COG0454	-acetyltransferase
NRZ52_27580	COG0745	RESPONSE REGULATOR receiver
NRZ52_27585	COG5002	protein histidine kinase activity
NRZ52_27595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ52_27600	COG0697	spore germination
NRZ52_27610	COG0281	malic enzyme
NRZ52_27615	COG3493	citrate carrier protein
NRZ52_27620	COG4565	transcriptional regulatory protein
NRZ52_27625	COG3290	protein histidine kinase activity
NRZ52_27635	COG4990	cell redox homeostasis
NRZ52_27645	COG5002	protein histidine kinase activity
NRZ52_27650	COG0745	RESPONSE REGULATOR receiver
NRZ52_27655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NRZ52_27665	COG0395	ABC-type sugar transport system, permease component
NRZ52_27675	COG3842	ATPase activity
NRZ52_27680	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NRZ52_27700	COG2851	Citrate transporter
NRZ52_27705	COG4565	transcriptional regulatory protein
NRZ52_27710	COG3290	protein histidine kinase activity
NRZ52_27720	COG2268	Band 7 protein
NRZ52_27725	COG1585	Membrane protein implicated in regulation of membrane protease activity
NRZ52_27735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NRZ52_27740	COG0765	amino acid transport
NRZ52_27745	COG0765	amino acid transport
NRZ52_27750	COG1126	abc transporter atp-binding protein
NRZ52_27755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ52_27785	COG4824	toxin secretion phage lysis holin
NRZ52_27915	COG0582	viral genome integration into host DNA
NRZ52_27920	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NRZ52_28010	COG0305	Participates in initiation and elongation during chromosome replication
NRZ52_28045	COG3620	sequence-specific DNA binding
NRZ52_28075	COG2766	serine protein kinase
NRZ52_28085	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NRZ52_28095	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NRZ52_28110	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NRZ52_28235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ52_28240	COG2323	membrane
NRZ52_28260	COG0582	viral genome integration into host DNA
NRZ52_28275	COG3655	Transcriptional regulator
NRZ52_28290	COG1733	regulation of RNA biosynthetic process
NRZ52_28300	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NRZ52_28310	COG2918	glutathione biosynthetic process
NRZ52_28310	COG1181	Belongs to the D-alanine--D-alanine ligase family
NRZ52_28360	COG0463	Glycosyl transferase, family 2
NRZ52_28395	COG0860	N-Acetylmuramoyl-L-alanine amidase
NRZ52_28440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ52_28455	COG2323	membrane
NRZ52_28480	COG0697	spore germination
NRZ52_28535	COG4974	Belongs to the 'phage' integrase family
NRZ52_28550	COG1183	phosphatidylcholine synthase activity
NRZ52_28570	COG0457	Tetratricopeptide repeat
NRZ52_28630	COG0210	DNA helicase
NRZ52_28660	COG0457	Tetratricopeptide repeat
NRZ52_28670	COG1045	serine acetyltransferase
NRZ52_28680	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NRZ52_28695	COG0456	acetyltransferase
NRZ52_28705	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NRZ52_28715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ52_28715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ52_28725	COG0745	RESPONSE REGULATOR receiver
NRZ52_28730	COG1522	sequence-specific DNA binding
NRZ52_28735	COG0531	amino acid
NRZ52_28775	COG3344	reverse transcriptase
NRZ52_28895	COG0640	Transcriptional regulator
NRZ52_28950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NRZ52_28965	COG0494	nUDIX hydrolase
NRZ52_28970	COG2368	4-hydroxyphenylacetate
NRZ52_28975	COG1475	DNA binding
NRZ52_28980	COG1611	Belongs to the LOG family
NRZ52_28985	COG3238	Protein conserved in bacteria
NRZ52_28990	COG0167	dihydroorotate dehydrogenase activity
NRZ52_29005	COG0546	phosphoglycolate phosphatase activity
NRZ52_29425	COG3344	reverse transcriptase
NRZ52_29485	COG2311	Membrane
NRZ52_29505	COG0457	Tetratricopeptide repeat
NRZ52_29560	COG0702	epimerase
NRZ52_29615	COG2002	toxin-antitoxin pair type II binding
NRZ52_29620	COG4166	transmembrane transport
NRZ52_29640	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NRZ52_29735	COG0463	Glycosyl transferase, family 2
NRZ52_29785	COG1131	(ABC) transporter
NRZ52_29900	COG1923	regulation of RNA biosynthetic process
NRZ52_30155	COG0697	spore germination
NRZ52_30180	COG2323	membrane
NRZ52_30195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ52_30235	COG0305	Participates in initiation and elongation during chromosome replication
NRZ52_30280	COG0756	dUTP diphosphatase activity
NRZ52_30285	COG0756	dUTP diphosphatase activity
NRZ52_30360	COG0322	excinuclease ABC activity
NRZ52_30370	COG5484	DNA packaging
NRZ52_30370	COG3728	DNA packaging
NRZ52_30390	COG5518	Phage portal protein
NRZ52_30395	COG2369	cell adhesion
NRZ52_30405	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NRZ52_30410	COG4653	Phage capsid family
NRZ52_30515	COG0322	excinuclease ABC activity
NRZ52_30555	COG1192	Involved in chromosome partitioning
NRZ52_30645	COG5377	YqaJ viral recombinase family
NRZ52_30650	COG3723	Recombinational DNA repair protein, rece pathway
NRZ52_30805	COG3654	unkown
NRZ52_30835	COG0662	Cupin 2, conserved barrel domain protein
NRZ52_30870	COG2002	toxin-antitoxin pair type II binding