locus-tag	class	description
NRZ50_00015	COG0753	catalase activity
NRZ50_00025	COG0598	Magnesium transport protein CorA
NRZ50_00065	COG0415	Belongs to the DNA photolyase family
NRZ50_00070	COG0288	reversible hydration of carbon dioxide
NRZ50_00080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NRZ50_00085	COG5609	conserved protein (DUF2294)
NRZ50_00115	COG1329	Transcriptional regulator
NRZ50_00130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ50_00140	COG1575	Belongs to the MenA family. Type 1 subfamily
NRZ50_00145	COG2267	carboxylic ester hydrolase activity
NRZ50_00150	COG4641	Protein conserved in bacteria
NRZ50_00155	COG1136	(ABC) transporter
NRZ50_00160	COG0577	efflux transmembrane transporter activity
NRZ50_00200	COG0798	PFAM Bile acid sodium symporter
NRZ50_00205	COG0346	lactoylglutathione lyase activity
NRZ50_00210	COG0640	Transcriptional regulator
NRZ50_00225	COG0443	Heat shock 70 kDa protein
NRZ50_00240	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_00245	COG1522	sequence-specific DNA binding
NRZ50_00260	COG0346	lactoylglutathione lyase activity
NRZ50_00280	COG2169	Transcriptional regulator
NRZ50_00315	COG2814	Major facilitator Superfamily
NRZ50_00325	COG4895	conserved protein (DUF2196)
NRZ50_00375	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NRZ50_00395	COG1476	TRANSCRIPTIONal
NRZ50_00410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ50_00415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ50_00425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ50_00450	COG0789	Transcriptional regulator
NRZ50_00455	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NRZ50_00475	COG0577	efflux transmembrane transporter activity
NRZ50_00505	COG1132	(ABC) transporter
NRZ50_00540	COG3850	Histidine kinase
NRZ50_00540	COG5002	protein histidine kinase activity
NRZ50_00550	COG2364	Membrane
NRZ50_00555	COG1846	Transcriptional regulator
NRZ50_00560	COG0456	acetyltransferase
NRZ50_00565	COG2808	Putative FMN-binding domain
NRZ50_00570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ50_00600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRZ50_00620	COG0662	Cupin 2, conserved barrel domain protein
NRZ50_00625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ50_00625	COG2207	Transcriptional regulator
NRZ50_00645	COG3409	Peptidoglycan-binding domain 1 protein
NRZ50_00645	COG5632	N-Acetylmuramoyl-L-alanine amidase
NRZ50_00690	COG0477	Major facilitator Superfamily
NRZ50_00705	COG1846	Transcriptional regulator
NRZ50_00710	COG2814	Major facilitator Superfamily
NRZ50_00725	COG2031	fatty acid transporter
NRZ50_00735	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRZ50_00770	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NRZ50_00785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NRZ50_00790	COG1288	antiporter activity
NRZ50_00815	COG0789	Transcriptional regulator
NRZ50_00845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NRZ50_00860	COG1733	regulation of RNA biosynthetic process
NRZ50_00865	COG0778	Nitroreductase
NRZ50_00885	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_00895	COG1131	(ABC) transporter
NRZ50_00920	COG1011	Hydrolase
NRZ50_00930	COG2365	Tyrosine phosphatase family
NRZ50_00955	COG0346	lactoylglutathione lyase activity
NRZ50_00960	COG1940	carbohydrate kinase activity
NRZ50_00965	COG0110	maltose O-acetyltransferase activity
NRZ50_00975	COG0577	efflux transmembrane transporter activity
NRZ50_00975	COG1136	(ABC) transporter
NRZ50_00995	COG0628	permease
NRZ50_01025	COG0500	methyltransferase
NRZ50_01035	COG0477	Major facilitator Superfamily
NRZ50_01060	COG1253	flavin adenine dinucleotide binding
NRZ50_01065	COG0789	Transcriptional regulator
NRZ50_01105	COG0697	spore germination
NRZ50_01110	COG1357	PFAM Pentapeptide repeats (8 copies)
NRZ50_01115	COG3813	Protein conserved in bacteria
NRZ50_01120	COG2706	6-phosphogluconolactonase activity
NRZ50_01125	COG1070	Carbohydrate kinase
NRZ50_01135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRZ50_01140	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NRZ50_01150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NRZ50_01155	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NRZ50_01160	COG0604	alcohol dehydrogenase
NRZ50_01165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NRZ50_01175	COG0604	alcohol dehydrogenase
NRZ50_01175	COG3321	synthase
NRZ50_01185	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_01200	COG0840	transmembrane signaling receptor activity
NRZ50_01210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ50_01210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ50_01215	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRZ50_01215	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NRZ50_01220	COG1733	regulation of RNA biosynthetic process
NRZ50_01235	COG0656	L-ascorbic acid biosynthetic process
NRZ50_01240	COG2814	Major facilitator Superfamily
NRZ50_01255	COG0346	lactoylglutathione lyase activity
NRZ50_01260	COG0814	amino acid
NRZ50_01290	COG1393	Belongs to the ArsC family
NRZ50_01295	COG1733	regulation of RNA biosynthetic process
NRZ50_01300	COG2188	Transcriptional regulator
NRZ50_01305	COG0673	inositol 2-dehydrogenase activity
NRZ50_01310	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NRZ50_01315	COG1733	regulation of RNA biosynthetic process
NRZ50_01320	COG1733	regulation of RNA biosynthetic process
NRZ50_01340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ50_01365	COG0384	phenazine biosynthesis protein PhzF
NRZ50_01375	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_01385	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ50_01390	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRZ50_01395	COG1733	regulation of RNA biosynthetic process
NRZ50_01420	COG1191	sigma factor activity
NRZ50_01455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NRZ50_01460	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NRZ50_01475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ50_01480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ50_01485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ50_01490	COG3739	integral membrane protein
NRZ50_01495	COG0384	phenazine biosynthesis protein PhzF
NRZ50_01530	COG0583	DNA-binding transcription factor activity
NRZ50_01560	COG1193	negative regulation of DNA recombination
NRZ50_01565	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NRZ50_01570	COG1164	Oligoendopeptidase f
NRZ50_01575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NRZ50_01605	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ50_01635	COG0640	Transcriptional regulator
NRZ50_01640	COG0604	alcohol dehydrogenase
NRZ50_01650	COG0457	Tetratricopeptide repeat
NRZ50_01660	COG2808	Putative FMN-binding domain
NRZ50_01675	COG0385	Bile acid
NRZ50_01680	COG0277	FAD linked oxidase domain protein
NRZ50_01720	COG1285	pathogenesis
NRZ50_01735	COG2514	catechol 2,3-dioxygenase activity
NRZ50_01740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ50_01745	COG1126	abc transporter atp-binding protein
NRZ50_01750	COG0765	amino acid transport
NRZ50_01755	COG2720	vancomycin resistance protein
NRZ50_01795	COG0716	FMN binding
NRZ50_01805	COG0494	nUDIX hydrolase
NRZ50_01825	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_01835	COG0165	Argininosuccinate lyase
NRZ50_01850	COG4145	pantothenate transmembrane transporter activity
NRZ50_01860	COG1012	belongs to the aldehyde dehydrogenase family
NRZ50_01865	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_01875	COG1657	PFAM Prenyltransferase squalene oxidase
NRZ50_01880	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NRZ50_01885	COG2962	Rard protein
NRZ50_01890	COG3326	Membrane
NRZ50_01905	COG0489	protein tyrosine kinase activity
NRZ50_01915	COG0314	molybdopterin synthase activity
NRZ50_01920	COG0303	'Molybdopterin
NRZ50_01925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ50_01930	COG2116	formate transmembrane transporter activity
NRZ50_01940	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRZ50_01945	COG5609	conserved protein (DUF2294)
NRZ50_01950	COG2427	Protein of unknown function (DUF1641)
NRZ50_01955	COG3383	formate dehydrogenase (NAD+) activity
NRZ50_01960	COG0697	spore germination
NRZ50_02005	COG2226	methyltransferase
NRZ50_02010	COG4166	transmembrane transport
NRZ50_02015	COG4166	transmembrane transport
NRZ50_02020	COG4166	transmembrane transport
NRZ50_02025	COG1301	dicarboxylic acid transport
NRZ50_02030	COG1316	TRANSCRIPTIONal
NRZ50_02040	COG1595	DNA-templated transcription, initiation
NRZ50_02055	COG3344	reverse transcriptase
NRZ50_02085	COG0673	inositol 2-dehydrogenase activity
NRZ50_02095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NRZ50_02100	COG0187	DNA topoisomerase II activity
NRZ50_02105	COG1832	CoA-binding protein
NRZ50_02110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRZ50_02115	COG0745	RESPONSE REGULATOR receiver
NRZ50_02135	COG4841	protein insertion into membrane
NRZ50_02140	COG0824	Thioesterase
NRZ50_02170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ50_02185	COG1132	(ABC) transporter
NRZ50_02190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NRZ50_02220	COG2211	Major facilitator Superfamily
NRZ50_02230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NRZ50_02245	COG0183	Belongs to the thiolase family
NRZ50_02250	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ50_02255	COG1268	BioY protein
NRZ50_02260	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ50_02275	COG1396	sequence-specific DNA binding
NRZ50_02325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ50_02335	COG5002	protein histidine kinase activity
NRZ50_02340	COG0400	carboxylic ester hydrolase activity
NRZ50_02345	COG0346	lactoylglutathione lyase activity
NRZ50_02350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ50_02355	COG0069	glutamate synthase activity
NRZ50_02360	COG1902	pentaerythritol trinitrate reductase activity
NRZ50_02365	COG1329	Transcriptional regulator
NRZ50_02370	COG0010	Belongs to the arginase family
NRZ50_02395	COG2226	methyltransferase
NRZ50_02430	COG4846	Membrane protein involved in cytochrome C biogenesis
NRZ50_02435	COG0785	Cytochrome C biogenesis protein
NRZ50_02445	COG1473	amidohydrolase
NRZ50_02455	COG1131	(ABC) transporter
NRZ50_02465	COG0583	DNA-binding transcription factor activity
NRZ50_02475	COG1346	cytolysis
NRZ50_02490	COG0730	response to heat
NRZ50_02500	COG3409	Peptidoglycan-binding domain 1 protein
NRZ50_02500	COG5632	N-Acetylmuramoyl-L-alanine amidase
NRZ50_02515	COG1132	(ABC) transporter
NRZ50_02520	COG1132	(ABC) transporter
NRZ50_02650	COG3639	organic phosphonate transmembrane transporter activity
NRZ50_02655	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NRZ50_02660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ50_02665	COG0737	Belongs to the 5'-nucleotidase family
NRZ50_02675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NRZ50_02695	COG1695	Transcriptional regulator
NRZ50_02700	COG0174	glutamine synthetase
NRZ50_02705	COG0789	Transcriptional regulator
NRZ50_02710	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NRZ50_02715	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NRZ50_02720	COG2860	membrane
NRZ50_02730	COG0464	growth
NRZ50_02765	COG1388	LysM domain
NRZ50_02765	COG3584	3D domain protein
NRZ50_02770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ50_02770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ50_02770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRZ50_02775	COG1105	Belongs to the carbohydrate kinase PfkB family
NRZ50_02780	COG1349	DNA-binding transcription factor activity
NRZ50_02785	COG1979	alcohol dehydrogenase
NRZ50_02790	COG2322	membrane
NRZ50_02800	COG1113	amino acid transport
NRZ50_02870	COG1408	metallophosphoesterase
NRZ50_02875	COG2116	formate transmembrane transporter activity
NRZ50_02890	COG2217	Heavy metal translocating P-type atpase
NRZ50_02895	COG2608	mercury ion transmembrane transporter activity
NRZ50_02900	COG1937	Protein conserved in bacteria
NRZ50_02910	COG1230	cation diffusion facilitator family transporter
NRZ50_02930	COG2819	hydrolase of the alpha beta superfamily
NRZ50_02935	COG1120	ATPase activity
NRZ50_02940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ50_02945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ50_02950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ50_02955	COG0708	Exodeoxyribonuclease III
NRZ50_02960	COG2169	Transcriptional regulator
NRZ50_02965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NRZ50_02970	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NRZ50_02980	COG2364	Membrane
NRZ50_02995	COG2267	carboxylic ester hydrolase activity
NRZ50_03000	COG0346	lactoylglutathione lyase activity
NRZ50_03005	COG5001	Diguanylate cyclase
NRZ50_03005	COG3300	MHYT domain
NRZ50_03025	COG1346	cytolysis
NRZ50_03030	COG1380	Effector of murein hydrolase LrgA
NRZ50_03035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ50_03055	COG1404	Belongs to the peptidase S8 family
NRZ50_03060	COG3773	Cell wall hydrolase
NRZ50_03070	COG1368	sulfuric ester hydrolase activity
NRZ50_03075	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NRZ50_03085	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NRZ50_03110	COG1131	(ABC) transporter
NRZ50_03130	COG4550	Control of competence regulator ComK, YlbF/YmcA
NRZ50_03140	COG1013	pyruvate-flavodoxin oxidoreductase activity
NRZ50_03145	COG0674	pyruvate-flavodoxin oxidoreductase activity
NRZ50_03145	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NRZ50_03155	COG2359	stage V sporulation protein S
NRZ50_03160	COG1692	metallophosphoesterase
NRZ50_03180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NRZ50_03185	COG1426	Protein conserved in bacteria
NRZ50_03200	COG0300	oxidoreductase activity
NRZ50_03205	COG0612	Peptidase, M16
NRZ50_03210	COG0612	Peptidase, M16
NRZ50_03215	COG1079	Belongs to the binding-protein-dependent transport system permease family
NRZ50_03220	COG4603	Belongs to the binding-protein-dependent transport system permease family
NRZ50_03225	COG3845	ABC transporter
NRZ50_03230	COG1744	ABC transporter substrate-binding protein PnrA-like
NRZ50_03235	COG2188	Transcriptional regulator
NRZ50_03240	COG1674	ftsk spoiiie
NRZ50_03250	COG0740	serine-type endopeptidase activity
NRZ50_03255	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NRZ50_03265	COG0527	aspartate kinase activity
NRZ50_03270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRZ50_03275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NRZ50_03280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRZ50_03285	COG1873	PFAM PRC-barrel domain
NRZ50_03290	COG0612	Peptidase, M16
NRZ50_03295	COG0726	polysaccharide deacetylase
NRZ50_03310	COG0196	riboflavin kinase activity
NRZ50_03315	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NRZ50_03325	COG1550	Protein conserved in bacteria
NRZ50_03335	COG1358	cellular component organization or biogenesis
NRZ50_03340	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NRZ50_03345	COG0195	Participates in both transcription termination and antitermination
NRZ50_03365	COG0750	zinc metalloprotease
NRZ50_03375	COG4589	Belongs to the CDS family
NRZ50_03390	COG0528	UMP kinase activity
NRZ50_03420	COG4974	Belongs to the 'phage' integrase family
NRZ50_03430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NRZ50_03435	COG0758	DNA mediated transformation
NRZ50_03440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NRZ50_03480	COG1837	Belongs to the UPF0109 family
NRZ50_03490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NRZ50_03500	COG0552	protein localization to endoplasmic reticulum
NRZ50_03505	COG1196	nuclear chromosome segregation
NRZ50_03515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRZ50_03520	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_03525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NRZ50_03540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NRZ50_03545	COG1461	Dihydroxyacetone kinase
NRZ50_03550	COG1302	Protein conserved in bacteria
NRZ50_03565	COG1564	THIamine pyrophosphokinase
NRZ50_03570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRZ50_03580	COG2815	serine threonine protein kinase
NRZ50_03580	COG0515	serine threonine protein kinase
NRZ50_03585	COG0631	protein serine/threonine phosphatase activity
NRZ50_03595	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NRZ50_03595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NRZ50_03605	COG0242	peptide deformylase activity
NRZ50_03610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NRZ50_03615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NRZ50_03635	COG1561	YicC-like family, N-terminal region
NRZ50_03640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NRZ50_03650	COG0006	proline dipeptidase activity
NRZ50_03670	COG3069	C4-dicarboxylate transmembrane transporter activity
NRZ50_03680	COG1011	Hydrolase
NRZ50_03735	COG0564	pseudouridine synthase activity
NRZ50_03755	COG3599	regulation of cell shape
NRZ50_03760	COG2302	S4 RNA-binding domain
NRZ50_03765	COG0762	integral membrane protein
NRZ50_03775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NRZ50_03785	COG1873	PFAM PRC-barrel domain
NRZ50_03790	COG1191	sigma factor activity
NRZ50_03795	COG1191	sigma factor activity
NRZ50_03805	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NRZ50_03810	COG0849	cell division
NRZ50_03815	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NRZ50_03830	COG0772	Belongs to the SEDS family
NRZ50_03845	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NRZ50_03850	COG0768	penicillin binding
NRZ50_03855	COG0768	penicillin binding
NRZ50_03860	COG4839	cell division protein FtsL
NRZ50_03875	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NRZ50_03890	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NRZ50_03895	COG1399	metal-binding, possibly nucleic acid-binding protein
NRZ50_03905	COG3480	Lon protease (S16) C-terminal proteolytic domain
NRZ50_03910	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRZ50_03915	COG3314	Sporulation integral membrane protein YlbJ
NRZ50_03925	COG0742	ribosomal rna small subunit methyltransferase
NRZ50_03940	COG3679	Belongs to the UPF0342 family
NRZ50_03945	COG0406	alpha-ribazole phosphatase activity
NRZ50_03960	COG2340	Cysteine-rich secretory protein family
NRZ50_03975	COG3344	reverse transcriptase
NRZ50_03985	COG3336	cytochrome c oxidase
NRZ50_04000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NRZ50_04020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NRZ50_04025	COG0772	Belongs to the SEDS family
NRZ50_04035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NRZ50_04040	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NRZ50_04050	COG4896	Protein conserved in bacteria
NRZ50_04065	COG1217	gtp-binding protein TYPA
NRZ50_04075	COG0483	inositol monophosphate 1-phosphatase activity
NRZ50_04095	COG1982	Orn Lys Arg decarboxylase major
NRZ50_04150	COG0022	dehydrogenase e1 component
NRZ50_04155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NRZ50_04165	COG0242	peptide deformylase activity
NRZ50_04170	COG0561	phosphatase activity
NRZ50_04180	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NRZ50_04185	COG0569	domain protein
NRZ50_04205	COG0583	DNA-binding transcription factor activity
NRZ50_04210	COG0517	IMP dehydrogenase activity
NRZ50_04220	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NRZ50_04230	COG4703	Protein of unknown function (DUF1797)
NRZ50_04250	COG2200	EAL domain
NRZ50_04255	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_04260	COG1408	metallophosphoesterase
NRZ50_04270	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NRZ50_04320	COG2814	Major facilitator Superfamily
NRZ50_04340	COG3209	COG3209 Rhs family protein
NRZ50_04350	COG2205	protein histidine kinase activity
NRZ50_04360	COG0436	Aminotransferase
NRZ50_04365	COG1609	Transcriptional regulator
NRZ50_04370	COG3833	ABC-type maltose transport systems, permease component
NRZ50_04375	COG1175	transmembrane transport
NRZ50_04380	COG2182	Extracellular solute-binding protein
NRZ50_04390	COG0366	Alpha amylase catalytic
NRZ50_04395	COG3842	ATPase activity
NRZ50_04435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NRZ50_04440	COG0183	Belongs to the thiolase family
NRZ50_04470	COG1695	Transcriptional regulator
NRZ50_04475	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_04495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRZ50_04500	COG0436	Aminotransferase
NRZ50_04535	COG2084	Dehydrogenase
NRZ50_04545	COG2199	diguanylate cyclase activity
NRZ50_04550	COG0778	Nitroreductase
NRZ50_04575	COG2190	(PTS) system
NRZ50_04575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ50_04575	COG1263	PTS System
NRZ50_04580	COG3711	transcriptional antiterminator
NRZ50_04590	COG2188	Transcriptional regulator
NRZ50_04600	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NRZ50_04625	COG1547	Domain of unknown function (DUF309)
NRZ50_04630	COG0456	acetyltransferase
NRZ50_04640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRZ50_04645	COG4086	secreted protein
NRZ50_04650	COG0561	phosphatase activity
NRZ50_04655	COG0697	spore germination
NRZ50_04670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ50_04695	COG0733	neurotransmitter:sodium symporter activity
NRZ50_04715	COG1686	Belongs to the peptidase S11 family
NRZ50_04720	COG1725	Transcriptional regulator
NRZ50_04725	COG1131	(ABC) transporter
NRZ50_04745	COG1846	Transcriptional regulator
NRZ50_04760	COG0598	Magnesium transport protein CorA
NRZ50_04785	COG4974	Belongs to the 'phage' integrase family
NRZ50_04795	COG0735	belongs to the Fur family
NRZ50_04800	COG1300	Membrane
NRZ50_04820	COG0667	Aldo Keto reductase
NRZ50_04825	COG0656	L-ascorbic acid biosynthetic process
NRZ50_04830	COG0456	acetyltransferase
NRZ50_04830	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NRZ50_04840	COG1525	nuclease
NRZ50_04840	COG4085	toxin activity
NRZ50_04840	COG0737	Belongs to the 5'-nucleotidase family
NRZ50_04850	COG0596	Alpha beta hydrolase
NRZ50_04855	COG2056	Na+-H+ antiporter family
NRZ50_04860	COG1609	Transcriptional regulator
NRZ50_04865	COG0456	acetyltransferase
NRZ50_04870	COG1073	alpha beta
NRZ50_04885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ50_04885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NRZ50_04890	COG0307	riboflavin synthase, alpha
NRZ50_04915	COG4106	trans-aconitate 2-methyltransferase activity
NRZ50_04920	COG1073	alpha beta
NRZ50_04920	COG2226	methyltransferase
NRZ50_04935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NRZ50_04945	COG1757	Na H antiporter
NRZ50_04950	COG0737	Belongs to the 5'-nucleotidase family
NRZ50_04980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NRZ50_05005	COG0300	oxidoreductase activity
NRZ50_05010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ50_05015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRZ50_05020	COG1760	l-serine dehydratase
NRZ50_05025	COG1760	l-serine dehydratase
NRZ50_05050	COG1285	pathogenesis
NRZ50_05065	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRZ50_05070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ50_05085	COG1376	ErfK ybiS ycfS ynhG family protein
NRZ50_05090	COG4129	membrane
NRZ50_05095	COG1126	abc transporter atp-binding protein
NRZ50_05100	COG0765	amino acid transport
NRZ50_05105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ50_05125	COG2323	membrane
NRZ50_05130	COG0772	Belongs to the SEDS family
NRZ50_05135	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRZ50_05140	COG0022	dehydrogenase e1 component
NRZ50_05145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NRZ50_05150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRZ50_05165	COG0280	phosphate acetyltransferase
NRZ50_05170	COG3829	transcription factor binding
NRZ50_05170	COG3290	protein histidine kinase activity
NRZ50_05180	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ50_05185	COG3093	addiction module antidote protein HigA
NRZ50_05230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NRZ50_05250	COG0322	excinuclease ABC activity
NRZ50_05270	COG0745	RESPONSE REGULATOR receiver
NRZ50_05275	COG0750	zinc metalloprotease
NRZ50_05280	COG0497	DNA recombination
NRZ50_05290	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NRZ50_05300	COG0142	geranyltranstransferase activity
NRZ50_05325	COG1302	Protein conserved in bacteria
NRZ50_05330	COG0439	Biotin carboxylase
NRZ50_05335	COG0511	ligase activity, forming carbon-carbon bonds
NRZ50_05380	COG3854	ATPases associated with a variety of cellular activities
NRZ50_05405	COG0006	proline dipeptidase activity
NRZ50_05420	COG3872	metal-dependent enzyme
NRZ50_05430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRZ50_05460	COG0095	Lipoate-protein ligase
NRZ50_05465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ50_05470	COG1609	Transcriptional regulator
NRZ50_05480	COG2076	Multidrug Resistance protein
NRZ50_05485	COG2076	Multidrug Resistance protein
NRZ50_05520	COG1131	(ABC) transporter
NRZ50_05525	COG1725	Transcriptional regulator
NRZ50_05555	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NRZ50_05705	COG0740	serine-type endopeptidase activity
NRZ50_05715	COG1802	Transcriptional regulator
NRZ50_05715	COG4626	Terminase
NRZ50_05760	COG0582	viral genome integration into host DNA
NRZ50_05785	COG0270	DNA (cytosine-5-)-methyltransferase activity
NRZ50_05845	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NRZ50_05850	COG1846	Transcriptional regulator
NRZ50_05920	COG4970	Tfp pilus assembly protein FimT
NRZ50_05930	COG1459	type II secretion system
NRZ50_05935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NRZ50_05985	COG0646	methionine synthase
NRZ50_05985	COG1410	methionine synthase
NRZ50_05990	COG0646	methionine synthase
NRZ50_05990	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NRZ50_05995	COG0626	cystathionine gamma-synthase activity
NRZ50_06000	COG0626	cystathionine gamma-synthase activity
NRZ50_06020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ50_06030	COG1940	carbohydrate kinase activity
NRZ50_06035	COG4483	Protein conserved in bacteria
NRZ50_06040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NRZ50_06045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NRZ50_06050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NRZ50_06055	COG0704	Plays a role in the regulation of phosphate uptake
NRZ50_06065	COG0581	inorganic phosphate transmembrane transporter activity
NRZ50_06070	COG0573	inorganic phosphate transmembrane transporter activity
NRZ50_06075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NRZ50_06080	COG0768	penicillin binding
NRZ50_06085	COG0477	Major facilitator Superfamily
NRZ50_06090	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NRZ50_06115	COG0735	belongs to the Fur family
NRZ50_06120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NRZ50_06125	COG1121	(ABC) transporter
NRZ50_06130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ50_06160	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NRZ50_06165	COG2384	SAM-dependent methyltransferase
NRZ50_06170	COG2010	Cytochrome c
NRZ50_06175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NRZ50_06180	COG0358	DNA primase activity
NRZ50_06195	COG0517	IMP dehydrogenase activity
NRZ50_06210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NRZ50_06215	COG0295	cytidine deaminase activity
NRZ50_06220	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NRZ50_06230	COG1480	7TM receptor with intracellular HD hydrolase
NRZ50_06235	COG1702	phosphate starvation-inducible protein PhoH
NRZ50_06250	COG1610	YqeY-like protein
NRZ50_06255	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NRZ50_06260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NRZ50_06265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NRZ50_06295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRZ50_06300	COG1733	regulation of RNA biosynthetic process
NRZ50_06325	COG1466	dna polymerase III delta subunit
NRZ50_06335	COG2333	competence protein COMEC
NRZ50_06335	COG0658	competence protein
NRZ50_06340	COG2131	deaminase
NRZ50_06345	COG1596	polysaccharide export
NRZ50_06345	COG1555	photosystem II stabilization
NRZ50_06350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRZ50_06355	COG2226	methyltransferase
NRZ50_06360	COG0799	negative regulation of ribosome biogenesis
NRZ50_06365	COG1713	HD superfamily hydrolase involved in NAD metabolism
NRZ50_06375	COG1534	Rna-binding protein
NRZ50_06385	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NRZ50_06390	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NRZ50_06425	COG0778	Nitroreductase
NRZ50_06430	COG2357	RelA SpoT domain protein
NRZ50_06440	COG1785	Belongs to the alkaline phosphatase family
NRZ50_06450	COG2267	carboxylic ester hydrolase activity
NRZ50_06485	COG1404	Belongs to the peptidase S8 family
NRZ50_06490	COG3186	Phenylalanine-4-hydroxylase
NRZ50_06500	COG2514	catechol 2,3-dioxygenase activity
NRZ50_06505	COG2259	Doxx family
NRZ50_06545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ50_06555	COG1454	alcohol dehydrogenase
NRZ50_06555	COG1012	belongs to the aldehyde dehydrogenase family
NRZ50_06560	COG0626	cystathionine gamma-synthase activity
NRZ50_06565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NRZ50_06590	COG0768	penicillin binding
NRZ50_06610	COG0826	peptidase U32
NRZ50_06615	COG0826	peptidase U32
NRZ50_06620	COG4122	O-methyltransferase activity
NRZ50_06625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NRZ50_06655	COG0628	permease
NRZ50_06675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NRZ50_06690	COG1104	cysteine desulfurase activity
NRZ50_06695	COG1959	2 iron, 2 sulfur cluster binding
NRZ50_06700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NRZ50_06710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NRZ50_06745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRZ50_06755	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NRZ50_06755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NRZ50_06760	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NRZ50_06765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ50_06765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NRZ50_06775	COG2244	polysaccharide biosynthetic process
NRZ50_06780	COG2323	membrane
NRZ50_06790	COG1862	Preprotein translocase
NRZ50_06820	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NRZ50_06830	COG0697	spore germination
NRZ50_06835	COG0640	Transcriptional regulator
NRZ50_06860	COG0157	Belongs to the NadC ModD family
NRZ50_06865	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NRZ50_06870	COG1104	cysteine desulfurase activity
NRZ50_06875	COG1827	regulation of RNA biosynthetic process
NRZ50_06880	COG2258	MOSC domain
NRZ50_06885	COG0077	Prephenate dehydratase
NRZ50_06890	COG0577	efflux transmembrane transporter activity
NRZ50_06895	COG0577	efflux transmembrane transporter activity
NRZ50_06900	COG1136	(ABC) transporter
NRZ50_06905	COG5002	protein histidine kinase activity
NRZ50_06910	COG0745	RESPONSE REGULATOR receiver
NRZ50_06920	COG3290	protein histidine kinase activity
NRZ50_06930	COG2868	ribosomal protein
NRZ50_06935	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NRZ50_06940	COG1530	ribonuclease E activity
NRZ50_06945	COG1994	Peptidase M50
NRZ50_06950	COG0739	heme binding
NRZ50_06955	COG2894	cell division
NRZ50_06975	COG1077	Cell shape determining protein MreB Mrl
NRZ50_06995	COG0285	dihydrofolate synthase activity
NRZ50_07010	COG1388	LysM domain
NRZ50_07020	COG0113	porphobilinogen synthase activity
NRZ50_07025	COG1587	Uroporphyrinogen-III synthase
NRZ50_07035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ50_07045	COG1846	Transcriptional regulator
NRZ50_07050	COG1764	response to oxidative stress
NRZ50_07065	COG1067	ATP-dependent peptidase activity
NRZ50_07065	COG0470	DNA polymerase III
NRZ50_07110	COG0457	Tetratricopeptide repeat
NRZ50_07130	COG0622	Phosphoesterase
NRZ50_07145	COG5401	PFAM Sporulation and spore germination
NRZ50_07155	COG2814	Major facilitator Superfamily
NRZ50_07165	COG1309	transcriptional regulator
NRZ50_07180	COG2197	response regulator
NRZ50_07185	COG2233	PERMEase
NRZ50_07190	COG0402	S-adenosylhomocysteine deaminase activity
NRZ50_07195	COG1983	PspC domain protein
NRZ50_07200	COG1396	sequence-specific DNA binding
NRZ50_07205	COG0697	spore germination
NRZ50_07215	COG1959	2 iron, 2 sulfur cluster binding
NRZ50_07220	COG1668	transmembrane transport
NRZ50_07225	COG4152	abc transporter atp-binding protein
NRZ50_07230	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NRZ50_07235	COG1360	Flagellar Motor Protein
NRZ50_07240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ50_07245	COG1876	peptidase activity
NRZ50_07250	COG0824	Thioesterase
NRZ50_07255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NRZ50_07260	COG1053	succinate dehydrogenase
NRZ50_07265	COG2009	succinate dehydrogenase
NRZ50_07270	COG1719	4-vinyl reductase, 4VR
NRZ50_07280	COG3118	belongs to the thioredoxin family
NRZ50_07285	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NRZ50_07290	COG2086	electron transfer activity
NRZ50_07295	COG1024	Enoyl-CoA hydratase
NRZ50_07300	COG1309	transcriptional regulator
NRZ50_07305	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ50_07320	COG2318	DinB family
NRZ50_07345	COG1131	(ABC) transporter
NRZ50_07350	COG2205	protein histidine kinase activity
NRZ50_07355	COG0745	RESPONSE REGULATOR receiver
NRZ50_07365	COG4895	conserved protein (DUF2196)
NRZ50_07370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NRZ50_07385	COG4509	Sortase family
NRZ50_07390	COG1120	ATPase activity
NRZ50_07405	COG5386	Cell surface protein
NRZ50_07410	COG5386	Cell surface protein
NRZ50_07415	COG1114	Component of the transport system for branched-chain amino acids
NRZ50_07420	COG1187	pseudouridine synthase activity
NRZ50_07430	COG1796	DNA polymerase
NRZ50_07430	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NRZ50_07435	COG1286	toxin biosynthetic process
NRZ50_07480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRZ50_07490	COG1418	mRNA catabolic process
NRZ50_07500	COG2814	Major facilitator Superfamily
NRZ50_07505	COG1566	PFAM secretion protein HlyD family protein
NRZ50_07510	COG1309	transcriptional regulator
NRZ50_07515	COG1363	Peptidase, m42
NRZ50_07540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NRZ50_07550	COG1484	DNA-dependent DNA replication
NRZ50_07555	COG3611	Membrane attachment protein
NRZ50_07565	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NRZ50_07570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRZ50_07575	COG0237	dephospho-CoA kinase activity
NRZ50_07580	COG1971	Probably functions as a manganese efflux pump
NRZ50_07590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ50_07590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ50_07595	COG5002	protein histidine kinase activity
NRZ50_07600	COG0745	RESPONSE REGULATOR receiver
NRZ50_07620	COG0538	isocitrate dehydrogenase activity
NRZ50_07625	COG0372	Belongs to the citrate synthase family
NRZ50_07635	COG0628	permease
NRZ50_07640	COG3030	protein affecting phage T7 exclusion by the F plasmid
NRZ50_07665	COG1725	Transcriptional regulator
NRZ50_07670	COG0281	malic enzyme
NRZ50_07675	COG0587	DNA-directed DNA polymerase activity
NRZ50_07690	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NRZ50_07710	COG4109	DRTGG domain
NRZ50_07725	COG0006	proline dipeptidase activity
NRZ50_07775	COG0662	Cupin 2, conserved barrel domain protein
NRZ50_07785	COG1476	TRANSCRIPTIONal
NRZ50_07800	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_07805	COG0589	response to stress
NRZ50_07855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ50_07880	COG0827	DNA restriction-modification system
NRZ50_07885	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NRZ50_07890	COG3874	Sporulation protein YtfJ
NRZ50_07905	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NRZ50_07915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRZ50_07930	COG1104	cysteine desulfurase activity
NRZ50_07940	COG0583	DNA-binding transcription factor activity
NRZ50_07945	COG0697	spore germination
NRZ50_07950	COG1309	transcriptional regulator
NRZ50_07955	COG1956	GAF domain-containing protein
NRZ50_07960	COG0626	cystathionine gamma-synthase activity
NRZ50_07990	COG1595	DNA-templated transcription, initiation
NRZ50_08000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRZ50_08005	COG0454	-acetyltransferase
NRZ50_08010	COG0517	IMP dehydrogenase activity
NRZ50_08015	COG0123	including yeast histone deacetylase and acetoin utilization protein
NRZ50_08020	COG2267	carboxylic ester hydrolase activity
NRZ50_08030	COG0745	RESPONSE REGULATOR receiver
NRZ50_08040	COG0666	response to abiotic stimulus
NRZ50_08075	COG1609	Transcriptional regulator
NRZ50_08085	COG4974	Belongs to the 'phage' integrase family
NRZ50_08110	COG4851	CamS sex pheromone cAM373 precursor
NRZ50_08115	COG3118	belongs to the thioredoxin family
NRZ50_08125	COG2309	aminopeptidase activity
NRZ50_08150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ50_08155	COG0697	spore germination
NRZ50_08160	COG0789	Transcriptional regulator
NRZ50_08175	COG1674	ftsk spoiiie
NRZ50_08185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ50_08195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ50_08200	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
NRZ50_08205	COG1363	Peptidase, m42
NRZ50_08215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ50_08230	COG0510	thiamine kinase activity
NRZ50_08235	COG1523	belongs to the glycosyl hydrolase 13 family
NRZ50_08245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRZ50_08250	COG1349	DNA-binding transcription factor activity
NRZ50_08255	COG1187	pseudouridine synthase activity
NRZ50_08260	COG2244	polysaccharide biosynthetic process
NRZ50_08265	COG2081	HI0933 family
NRZ50_08270	COG2814	Major facilitator Superfamily
NRZ50_08280	COG3832	glyoxalase III activity
NRZ50_08300	COG1329	Transcriptional regulator
NRZ50_08325	COG0314	molybdopterin synthase activity
NRZ50_08330	COG1763	Mo-molybdopterin cofactor biosynthetic process
NRZ50_08335	COG0303	'Molybdopterin
NRZ50_08345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ50_08350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NRZ50_08370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ50_08380	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NRZ50_08425	COG2814	Major facilitator Superfamily
NRZ50_08430	COG0475	glutathione-regulated potassium exporter activity
NRZ50_08435	COG0490	domain, Protein
NRZ50_08440	COG0582	viral genome integration into host DNA
NRZ50_08450	COG1136	(ABC) transporter
NRZ50_08470	COG1242	4 iron, 4 sulfur cluster binding
NRZ50_08475	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NRZ50_08490	COG1794	racemase activity, acting on amino acids and derivatives
NRZ50_08500	COG5504	Zn-dependent protease
NRZ50_08525	COG2267	carboxylic ester hydrolase activity
NRZ50_08530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NRZ50_08535	COG0671	phosphoesterase, PA-phosphatase related
NRZ50_08540	COG0438	transferase activity, transferring glycosyl groups
NRZ50_08550	COG0521	Mo-molybdopterin cofactor biosynthetic process
NRZ50_08560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ50_08600	COG0546	phosphoglycolate phosphatase activity
NRZ50_08605	COG1349	DNA-binding transcription factor activity
NRZ50_08615	COG5002	protein histidine kinase activity
NRZ50_08620	COG4191	Histidine kinase
NRZ50_08625	COG2267	carboxylic ester hydrolase activity
NRZ50_08630	COG1368	sulfuric ester hydrolase activity
NRZ50_08655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NRZ50_08660	COG1116	anion transmembrane transporter activity
NRZ50_08665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ50_08690	COG0494	nUDIX hydrolase
NRZ50_08720	COG0288	reversible hydration of carbon dioxide
NRZ50_08725	COG1271	oxidase subunit
NRZ50_08730	COG1294	oxidase, subunit
NRZ50_08750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ50_08775	COG1842	Phage shock protein A
NRZ50_08825	COG5002	protein histidine kinase activity
NRZ50_08830	COG0745	RESPONSE REGULATOR receiver
NRZ50_08860	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NRZ50_08865	COG1597	lipid kinase activity
NRZ50_08880	COG0577	efflux transmembrane transporter activity
NRZ50_08885	COG1136	(ABC) transporter
NRZ50_08900	COG0586	Pfam SNARE associated Golgi protein
NRZ50_08915	COG1136	(ABC) transporter
NRZ50_08920	COG2207	Transcriptional regulator
NRZ50_08920	COG3708	Transcriptional regulator
NRZ50_08930	COG5658	integral membrane protein
NRZ50_08935	COG0640	Transcriptional regulator
NRZ50_08940	COG0745	RESPONSE REGULATOR receiver
NRZ50_08945	COG2205	protein histidine kinase activity
NRZ50_08955	COG0577	efflux transmembrane transporter activity
NRZ50_08960	COG1136	(ABC) transporter
NRZ50_08965	COG0577	efflux transmembrane transporter activity
NRZ50_08990	COG2188	Transcriptional regulator
NRZ50_09010	COG3964	amidohydrolase
NRZ50_09035	COG4948	Mandelate Racemase Muconate Lactonizing
NRZ50_09045	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NRZ50_09050	COG0596	Alpha beta hydrolase
NRZ50_09060	COG1169	isochorismate synthase
NRZ50_09065	COG1575	Belongs to the MenA family. Type 1 subfamily
NRZ50_09070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NRZ50_09095	COG0058	SHG alpha-glucan phosphorylase activity
NRZ50_09105	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NRZ50_09125	COG1404	Belongs to the peptidase S8 family
NRZ50_09140	COG1595	DNA-templated transcription, initiation
NRZ50_09230	COG0544	peptidyl-prolyl cis-trans isomerase activity
NRZ50_09265	COG1285	pathogenesis
NRZ50_09270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NRZ50_09285	COG2155	Conserved Protein
NRZ50_09290	COG1098	S1 RNA binding domain
NRZ50_09295	COG0436	Aminotransferase
NRZ50_09300	COG1522	sequence-specific DNA binding
NRZ50_09305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRZ50_09310	COG2267	carboxylic ester hydrolase activity
NRZ50_09320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRZ50_09340	COG5018	Exonuclease
NRZ50_09345	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NRZ50_09365	COG2050	protein possibly involved in aromatic compounds catabolism
NRZ50_09375	COG1268	BioY protein
NRZ50_09385	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NRZ50_09390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NRZ50_09405	COG3584	3D domain protein
NRZ50_09420	COG1252	NADH dehydrogenase
NRZ50_09435	COG3708	Transcriptional regulator
NRZ50_09450	COG1683	Conserved Protein
NRZ50_09470	COG0316	Belongs to the HesB IscA family
NRZ50_09485	COG1252	NADH dehydrogenase
NRZ50_09495	COG2274	protein secretion by the type I secretion system
NRZ50_09500	COG0390	transport system, permease component
NRZ50_09545	COG4837	Protein of unknown function (DUF1462)
NRZ50_09550	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NRZ50_09560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NRZ50_09565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NRZ50_09585	COG1358	cellular component organization or biogenesis
NRZ50_09595	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRZ50_09605	COG0647	UMP catabolic process
NRZ50_09615	COG2445	Protein of unknown function DUF86
NRZ50_09620	COG1494	fructose-1,6-bisphosphatase
NRZ50_09635	COG4470	Protein conserved in bacteria
NRZ50_09645	COG0789	Transcriptional regulator
NRZ50_09650	COG4377	Putative membrane peptidase family (DUF2324)
NRZ50_09675	COG0739	heme binding
NRZ50_09685	COG3377	Domain of unknown function (DUF1805)
NRZ50_09690	COG0737	Belongs to the 5'-nucleotidase family
NRZ50_09695	COG0719	Fe-S assembly protein
NRZ50_09700	COG0822	iron-sulfur transferase activity
NRZ50_09705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRZ50_09710	COG0719	Fe-S assembly protein
NRZ50_09715	COG0396	ATPase activity
NRZ50_09720	COG1464	Belongs to the NlpA lipoprotein family
NRZ50_09725	COG1464	Belongs to the NlpA lipoprotein family
NRZ50_09730	COG2011	ABC-type metal ion transport system permease component
NRZ50_09745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ50_09750	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NRZ50_09760	COG1393	Belongs to the ArsC family
NRZ50_09810	COG1309	transcriptional regulator
NRZ50_09815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ50_09820	COG1960	acyl-CoA dehydrogenase activity
NRZ50_09830	COG0183	Belongs to the thiolase family
NRZ50_09835	COG1024	Enoyl-CoA hydratase
NRZ50_09835	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRZ50_09845	COG1686	Belongs to the peptidase S11 family
NRZ50_09860	COG0011	TIGRFAM Protein of
NRZ50_09865	COG0840	transmembrane signaling receptor activity
NRZ50_09890	COG2814	Major facilitator Superfamily
NRZ50_09895	COG0531	amino acid
NRZ50_09915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ50_09955	COG0586	Pfam SNARE associated Golgi protein
NRZ50_09965	COG1376	ErfK ybiS ycfS ynhG family protein
NRZ50_09970	COG0745	RESPONSE REGULATOR receiver
NRZ50_09975	COG5002	protein histidine kinase activity
NRZ50_10010	COG2151	metal-sulfur cluster biosynthetic enzyme
NRZ50_10015	COG3227	Zinc metalloprotease (Elastase)
NRZ50_10020	COG1741	Belongs to the pirin family
NRZ50_10035	COG0475	glutathione-regulated potassium exporter activity
NRZ50_10040	COG0490	domain, Protein
NRZ50_10045	COG1115	amino acid carrier protein
NRZ50_10050	COG0783	Belongs to the Dps family
NRZ50_10065	COG1611	Belongs to the LOG family
NRZ50_10085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ50_10090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ50_10095	COG1115	amino acid carrier protein
NRZ50_10100	COG1115	amino acid carrier protein
NRZ50_10105	COG2910	NAD(P)H-binding
NRZ50_10120	COG0656	L-ascorbic acid biosynthetic process
NRZ50_10125	COG2814	Major facilitator Superfamily
NRZ50_10130	COG1733	regulation of RNA biosynthetic process
NRZ50_10140	COG1252	NADH dehydrogenase
NRZ50_10145	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NRZ50_10160	COG0840	transmembrane signaling receptor activity
NRZ50_10160	COG3290	protein histidine kinase activity
NRZ50_10170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NRZ50_10185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ50_10250	COG0557	exoribonuclease II activity
NRZ50_10255	COG1647	Serine aminopeptidase, S33
NRZ50_10260	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRZ50_10265	COG1346	cytolysis
NRZ50_10300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NRZ50_10315	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NRZ50_10335	COG0457	Tetratricopeptide repeat
NRZ50_10410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NRZ50_10430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ50_10445	COG2323	membrane
NRZ50_10455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ50_10465	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NRZ50_10475	COG1051	belongs to the nudix hydrolase family
NRZ50_10485	COG0492	ferredoxin-NADP+ reductase activity
NRZ50_10490	COG0457	Tetratricopeptide repeat
NRZ50_10495	COG0110	maltose O-acetyltransferase activity
NRZ50_10515	COG1950	PFAM Membrane protein of
NRZ50_10525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRZ50_10540	COG0789	Transcriptional regulator
NRZ50_10575	COG0583	DNA-binding transcription factor activity
NRZ50_10585	COG0655	NAD(P)H dehydrogenase (quinone) activity
NRZ50_10590	COG0488	(ABC) transporter
NRZ50_10600	COG1132	(ABC) transporter
NRZ50_10605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRZ50_10610	COG3409	Peptidoglycan-binding domain 1 protein
NRZ50_10610	COG0793	Belongs to the peptidase S41A family
NRZ50_10615	COG2177	Part of the ABC transporter FtsEX involved in
NRZ50_10620	COG2884	Cell division ATP-binding protein ftsE
NRZ50_10645	COG1131	(ABC) transporter
NRZ50_10675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NRZ50_10680	COG1278	Cold shock
NRZ50_10685	COG1040	competence protein
NRZ50_10690	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NRZ50_10695	COG1388	LysM domain
NRZ50_10695	COG0791	NLP P60 protein
NRZ50_10700	COG1733	regulation of RNA biosynthetic process
NRZ50_10705	COG1307	EDD domain protein, DegV family
NRZ50_10710	COG1739	Uncharacterized protein family UPF0029
NRZ50_10730	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NRZ50_10735	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NRZ50_10740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRZ50_10750	COG3933	PFAM sigma-54 factor interaction domain-containing protein
NRZ50_10750	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NRZ50_10770	COG1486	melibiose metabolic process
NRZ50_10775	COG1447	Phosphotransferase system cellobiose-specific component IIA
NRZ50_10780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NRZ50_10800	COG1447	Phosphotransferase system cellobiose-specific component IIA
NRZ50_10810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NRZ50_10815	COG1301	dicarboxylic acid transport
NRZ50_10825	COG0346	lactoylglutathione lyase activity
NRZ50_10845	COG1511	domain protein
NRZ50_10850	COG0583	DNA-binding transcription factor activity
NRZ50_10855	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NRZ50_10865	COG1271	oxidase subunit
NRZ50_10870	COG1294	oxidase, subunit
NRZ50_10875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NRZ50_10885	COG1620	l-lactate permease
NRZ50_10895	COG2389	metal-binding protein
NRZ50_10905	COG1368	sulfuric ester hydrolase activity
NRZ50_10915	COG1388	LysM domain
NRZ50_10915	COG0791	NLP P60 protein
NRZ50_10920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ50_10930	COG1215	transferase activity, transferring glycosyl groups
NRZ50_10935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NRZ50_10940	COG1388	LysM domain
NRZ50_10940	COG3584	3D domain protein
NRZ50_10965	COG4715	Zinc finger, swim domain protein
NRZ50_10970	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NRZ50_11010	COG0577	efflux transmembrane transporter activity
NRZ50_11015	COG1136	(ABC) transporter
NRZ50_11035	COG2271	Major facilitator Superfamily
NRZ50_11050	COG5002	protein histidine kinase activity
NRZ50_11055	COG0745	RESPONSE REGULATOR receiver
NRZ50_11060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRZ50_11100	COG1216	Glycosyl transferase, family 2
NRZ50_11120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NRZ50_11125	COG4464	protein tyrosine phosphatase activity
NRZ50_11130	COG0489	protein tyrosine kinase activity
NRZ50_11135	COG3944	biosynthesis protein
NRZ50_11140	COG0489	protein tyrosine kinase activity
NRZ50_11155	COG1609	Transcriptional regulator
NRZ50_11165	COG0739	heme binding
NRZ50_11180	COG3279	Response regulator of the LytR AlgR family
NRZ50_11185	COG2385	sporulation resulting in formation of a cellular spore
NRZ50_11200	COG4836	Membrane
NRZ50_11205	COG1007	ATP synthesis coupled electron transport
NRZ50_11210	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ50_11215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NRZ50_11225	COG0839	Belongs to the complex I subunit 6 family
NRZ50_11245	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NRZ50_11260	COG5001	Diguanylate cyclase
NRZ50_11260	COG3300	MHYT domain
NRZ50_11310	COG0356	it plays a direct role in the translocation of protons across the membrane
NRZ50_11345	COG0698	ribose 5-phosphate isomerase
NRZ50_11355	COG2190	(PTS) system
NRZ50_11360	COG2259	Doxx family
NRZ50_11365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NRZ50_11385	COG0009	L-threonylcarbamoyladenylate synthase
NRZ50_11400	COG2890	protein-(glutamine-N5) methyltransferase activity
NRZ50_11420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NRZ50_11425	COG1494	fructose-1,6-bisphosphatase
NRZ50_11445	COG4821	SIS domain
NRZ50_11455	COG3343	RNA polymerase activity
NRZ50_11465	COG1960	acyl-CoA dehydrogenase activity
NRZ50_11470	COG1960	acyl-CoA dehydrogenase activity
NRZ50_11475	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRZ50_11485	COG0247	lactate metabolic process
NRZ50_11485	COG2181	nitrate reductase activity
NRZ50_11490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ50_11500	COG3300	MHYT domain
NRZ50_11500	COG5001	Diguanylate cyclase
NRZ50_11520	COG2197	response regulator
NRZ50_11525	COG4585	Histidine kinase
NRZ50_11530	COG0842	Transport permease protein
NRZ50_11535	COG1131	(ABC) transporter
NRZ50_11540	COG0024	Methionine aminopeptidase
NRZ50_11550	COG2234	aminopeptidase activity
NRZ50_11570	COG1595	DNA-templated transcription, initiation
NRZ50_11580	COG4506	Protein conserved in bacteria
NRZ50_11585	COG1619	proteins homologs of microcin C7 resistance protein MccF
NRZ50_11610	COG2814	Major facilitator Superfamily
NRZ50_11615	COG0789	Transcriptional regulator
NRZ50_11620	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ50_11625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ50_11635	COG1994	Peptidase M50
NRZ50_11645	COG1078	dGTPase activity
NRZ50_11650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ50_11655	COG1120	ATPase activity
NRZ50_11660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ50_11665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ50_11690	COG0280	phosphate acetyltransferase
NRZ50_11705	COG3773	Cell wall hydrolase
NRZ50_11715	COG2363	Small membrane protein
NRZ50_11725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NRZ50_11730	COG2233	PERMEase
NRZ50_11735	COG0561	phosphatase activity
NRZ50_11740	COG2814	Major facilitator Superfamily
NRZ50_11750	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NRZ50_11755	COG1131	(ABC) transporter
NRZ50_11760	COG2755	lipolytic protein G-D-S-L family
NRZ50_11765	COG1609	Transcriptional regulator
NRZ50_11775	COG0460	homoserine dehydrogenase
NRZ50_11785	COG2873	o-acetylhomoserine
NRZ50_11790	COG1011	Hydrolase
NRZ50_11795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRZ50_11805	COG2197	response regulator
NRZ50_11810	COG2203	Gaf domain
NRZ50_11810	COG4585	Histidine kinase
NRZ50_11815	COG0351	phosphomethylpyrimidine kinase
NRZ50_11820	COG3706	GGDEF domain
NRZ50_11825	COG2879	small protein
NRZ50_11835	COG3279	Response regulator of the LytR AlgR family
NRZ50_11840	COG0477	Major facilitator Superfamily
NRZ50_11850	COG0438	transferase activity, transferring glycosyl groups
NRZ50_11865	COG0840	transmembrane signaling receptor activity
NRZ50_11875	COG1607	acyl-coa hydrolase
NRZ50_11880	COG1216	Glycosyl transferase, family 2
NRZ50_11890	COG1216	Glycosyl transferase, family 2
NRZ50_11905	COG0488	(ABC) transporter
NRZ50_11920	COG0463	Glycosyl transferase, family 2
NRZ50_11925	COG1309	transcriptional regulator
NRZ50_11930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ50_11935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRZ50_11935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRZ50_11940	COG0628	permease
NRZ50_11955	COG3279	Response regulator of the LytR AlgR family
NRZ50_11960	COG3275	phosphorelay sensor kinase activity
NRZ50_11965	COG2814	Major facilitator Superfamily
NRZ50_11980	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NRZ50_11985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NRZ50_12030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NRZ50_12035	COG1272	protein, Hemolysin III
NRZ50_12055	COG1164	Oligoendopeptidase f
NRZ50_12065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NRZ50_12135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NRZ50_12140	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NRZ50_12145	COG4853	Protein conserved in bacteria
NRZ50_12150	COG4863	YycH protein
NRZ50_12155	COG5002	protein histidine kinase activity
NRZ50_12160	COG0745	RESPONSE REGULATOR receiver
NRZ50_12190	COG0305	Participates in initiation and elongation during chromosome replication
NRZ50_12200	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NRZ50_12205	COG4241	membrane
NRZ50_12215	COG0629	single-stranded DNA binding
NRZ50_12225	COG0012	GTP binding
NRZ50_12230	COG4481	Protein conserved in bacteria
NRZ50_12235	COG0668	transmembrane transport
NRZ50_12245	COG1475	DNA binding
NRZ50_12250	COG1192	Involved in chromosome partitioning
NRZ50_12275	COG1847	R3H domain protein
NRZ50_12280	COG0706	membrane insertase activity
NRZ50_12290	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NRZ50_12300	COG0592	DNA-directed DNA polymerase activity
NRZ50_12305	COG2501	S4 domain
NRZ50_12315	COG0187	DNA topoisomerase II activity
NRZ50_12320	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NRZ50_12355	COG0516	GMP reductase activity
NRZ50_12355	COG0517	IMP dehydrogenase activity
NRZ50_12360	COG1686	Belongs to the peptidase S11 family
NRZ50_12390	COG1428	Deoxynucleoside kinase
NRZ50_12395	COG1428	Deoxynucleoside kinase
NRZ50_12400	COG1335	isochorismatase
NRZ50_12405	COG0590	tRNA wobble adenosine to inosine editing
NRZ50_12415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NRZ50_12470	COG1982	Orn Lys Arg decarboxylase major
NRZ50_12480	COG0470	DNA polymerase III
NRZ50_12485	COG1774	PSP1 C-terminal conserved region
NRZ50_12495	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NRZ50_12505	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NRZ50_12510	COG2002	toxin-antitoxin pair type II binding
NRZ50_12515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ50_12515	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ50_12520	COG0084	hydrolase, TatD family'
NRZ50_12525	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NRZ50_12540	COG4466	Protein conserved in bacteria
NRZ50_12555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NRZ50_12560	COG0251	oxidation-reduction process
NRZ50_12590	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NRZ50_12595	COG2002	toxin-antitoxin pair type II binding
NRZ50_12600	COG2244	polysaccharide biosynthetic process
NRZ50_12605	COG3956	TIGRFAM MazG family protein
NRZ50_12610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NRZ50_12630	COG1098	S1 RNA binding domain
NRZ50_12645	COG2208	phosphoserine phosphatase activity
NRZ50_12655	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NRZ50_12660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NRZ50_12675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NRZ50_12680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NRZ50_12685	COG0512	Glutamine amidotransferase of anthranilate synthase
NRZ50_12690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRZ50_12695	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NRZ50_12700	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NRZ50_12705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NRZ50_12710	COG1396	sequence-specific DNA binding
NRZ50_12715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRZ50_12805	COG3880	PFAM UvrB UvrC protein
NRZ50_12815	COG0542	response to heat
NRZ50_12820	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NRZ50_12830	COG4956	integral membrane protein (PIN domain superfamily)
NRZ50_12850	COG1045	serine acetyltransferase
NRZ50_12865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRZ50_12870	COG3688	RNA-binding protein containing a PIN domain
NRZ50_12885	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRZ50_12890	COG0250	Participates in transcription elongation, termination and antitermination
NRZ50_12895	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NRZ50_12915	COG2813	Specifically methylates the guanine in position
NRZ50_12930	COG1358	cellular component organization or biogenesis
NRZ50_13000	COG0255	Belongs to the universal ribosomal protein uL29 family
NRZ50_13060	COG0201	protein transport
NRZ50_13070	COG0024	Methionine aminopeptidase
NRZ50_13080	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NRZ50_13085	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NRZ50_13115	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NRZ50_13140	COG0860	N-Acetylmuramoyl-L-alanine amidase
NRZ50_13145	COG0489	protein tyrosine kinase activity
NRZ50_13155	COG2194	sulfuric ester hydrolase activity
NRZ50_13160	COG0726	polysaccharide deacetylase
NRZ50_13240	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NRZ50_13245	COG4856	YbbR-like protein
NRZ50_13295	COG1063	alcohol dehydrogenase
NRZ50_13305	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_13320	COG0596	Alpha beta hydrolase
NRZ50_13340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NRZ50_13375	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_13380	COG2011	ABC-type metal ion transport system permease component
NRZ50_13390	COG1464	Belongs to the NlpA lipoprotein family
NRZ50_13395	COG0604	alcohol dehydrogenase
NRZ50_13405	COG0277	FAD linked oxidase domain protein
NRZ50_13410	COG2271	Major facilitator Superfamily
NRZ50_13420	COG2814	Major facilitator Superfamily
NRZ50_13435	COG0601	transmembrane transport
NRZ50_13440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ50_13445	COG0444	Belongs to the ABC transporter superfamily
NRZ50_13450	COG4608	Belongs to the ABC transporter superfamily
NRZ50_13455	COG4166	transmembrane transport
NRZ50_13465	COG2207	Transcriptional regulator
NRZ50_13475	COG1309	transcriptional regulator
NRZ50_13490	COG4166	transmembrane transport
NRZ50_13495	COG0656	L-ascorbic acid biosynthetic process
NRZ50_13500	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRZ50_13515	COG4149	molybdate abc transporter
NRZ50_13520	COG0725	ABC transporter, periplasmic molybdate-binding protein
NRZ50_13525	COG1910	domain protein
NRZ50_13540	COG0697	spore germination
NRZ50_13555	COG0204	Acyl-transferase
NRZ50_13565	COG1609	Transcriptional regulator
NRZ50_13575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ50_13585	COG0084	hydrolase, TatD family'
NRZ50_13595	COG5298	Protein conserved in bacteria
NRZ50_13620	COG0488	(ABC) transporter
NRZ50_13625	COG4585	Histidine kinase
NRZ50_13630	COG2197	response regulator
NRZ50_13635	COG1131	(ABC) transporter
NRZ50_13640	COG1511	domain protein
NRZ50_13640	COG0842	Transport permease protein
NRZ50_13645	COG0842	Transport permease protein
NRZ50_13655	COG0747	negative chemotaxis
NRZ50_13660	COG0747	negative chemotaxis
NRZ50_13665	COG0601	transmembrane transport
NRZ50_13670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ50_13675	COG0444	Belongs to the ABC transporter superfamily
NRZ50_13680	COG4608	Belongs to the ABC transporter superfamily
NRZ50_13685	COG0561	phosphatase activity
NRZ50_13715	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NRZ50_13720	COG0179	Fumarylacetoacetate (FAA) hydrolase
NRZ50_13730	COG0531	amino acid
NRZ50_13745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRZ50_13755	COG4294	response to UV
NRZ50_13760	COG0705	Rhomboid family
NRZ50_13770	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NRZ50_13775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRZ50_13780	COG0864	Transcriptional regulator
NRZ50_13785	COG2337	Toxic component of a toxin-antitoxin (TA) module
NRZ50_13790	COG2183	response to ionizing radiation
NRZ50_13885	COG0802	atpase or kinase
NRZ50_13890	COG1214	PFAM Peptidase M22, glycoprotease
NRZ50_13895	COG0456	acetyltransferase
NRZ50_13905	COG0488	(ABC) transporter
NRZ50_13920	COG1266	CAAX protease self-immunity
NRZ50_13950	COG2252	PERMEase
NRZ50_13960	COG5002	protein histidine kinase activity
NRZ50_13985	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NRZ50_14015	COG2226	methyltransferase
NRZ50_14035	COG1215	transferase activity, transferring glycosyl groups
NRZ50_14060	COG0697	spore germination
NRZ50_14085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NRZ50_14090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NRZ50_14095	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NRZ50_14105	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NRZ50_14120	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NRZ50_14130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NRZ50_14140	COG0151	Belongs to the GarS family
NRZ50_14165	COG0210	DNA helicase
NRZ50_14175	COG4851	CamS sex pheromone cAM373 precursor
NRZ50_14195	COG1335	isochorismatase
NRZ50_14205	COG2011	ABC-type metal ion transport system permease component
NRZ50_14210	COG1464	Belongs to the NlpA lipoprotein family
NRZ50_14225	COG0003	Pfam Anion-transporting ATPase
NRZ50_14230	COG1846	Transcriptional regulator
NRZ50_14235	COG4682	membrane
NRZ50_14255	COG1597	lipid kinase activity
NRZ50_14260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NRZ50_14265	COG0546	phosphoglycolate phosphatase activity
NRZ50_14270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NRZ50_14280	COG1012	belongs to the aldehyde dehydrogenase family
NRZ50_14285	COG2076	Multidrug Resistance protein
NRZ50_14290	COG2309	aminopeptidase activity
NRZ50_14300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ50_14305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NRZ50_14310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NRZ50_14320	COG0028	Belongs to the TPP enzyme family
NRZ50_14330	COG4807	Protein conserved in bacteria
NRZ50_14360	COG1757	Na H antiporter
NRZ50_14365	COG1473	amidohydrolase
NRZ50_14380	COG0450	alkyl hydroperoxide reductase
NRZ50_14400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ50_14405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ50_14410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ50_14425	COG0166	Belongs to the GPI family
NRZ50_14465	COG3541	Predicted nucleotidyltransferase
NRZ50_14475	COG2814	Major facilitator Superfamily
NRZ50_14480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ50_14480	COG0723	plastoquinol--plastocyanin reductase activity
NRZ50_14505	COG0765	amino acid transport
NRZ50_14510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ50_14520	COG0840	transmembrane signaling receptor activity
NRZ50_14525	COG0840	transmembrane signaling receptor activity
NRZ50_14530	COG0277	FAD linked oxidase domain protein
NRZ50_14535	COG0366	Alpha amylase catalytic
NRZ50_14540	COG2190	(PTS) system
NRZ50_14540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ50_14540	COG1263	PTS System
NRZ50_14585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ50_14595	COG1116	anion transmembrane transporter activity
NRZ50_14600	COG0488	(ABC) transporter
NRZ50_14650	COG2270	Major facilitator Superfamily
NRZ50_14680	COG2310	stress, protein
NRZ50_14685	COG2310	stress, protein
NRZ50_14690	COG2310	stress, protein
NRZ50_14695	COG0861	Integral membrane protein TerC family
NRZ50_14705	COG3853	Toxic anion resistance protein (TelA)
NRZ50_14720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NRZ50_14730	COG1295	ribonuclease BN
NRZ50_14735	COG2217	Heavy metal translocating P-type atpase
NRZ50_14740	COG0697	spore germination
NRZ50_14765	COG0586	Pfam SNARE associated Golgi protein
NRZ50_14780	COG3871	stress protein (general stress protein 26)
NRZ50_14785	COG0387	Pfam Sodium calcium exchanger
NRZ50_14795	COG0535	radical SAM domain protein
NRZ50_14815	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NRZ50_14835	COG3829	transcription factor binding
NRZ50_14845	COG0833	amino acid
NRZ50_14850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRZ50_14880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ50_14880	COG1263	PTS System
NRZ50_14885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NRZ50_14900	COG0463	Glycosyl transferase, family 2
NRZ50_14910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NRZ50_14910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ50_14925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NRZ50_14945	COG0402	S-adenosylhomocysteine deaminase activity
NRZ50_14950	COG1090	epimerase
NRZ50_14980	COG1988	membrane-bound metal-dependent
NRZ50_14985	COG1194	a g-specific adenine glycosylase
NRZ50_15010	COG1132	(ABC) transporter
NRZ50_15015	COG4129	membrane
NRZ50_15020	COG0069	glutamate synthase activity
NRZ50_15020	COG0070	glutamate synthase
NRZ50_15020	COG0067	glutamate synthase
NRZ50_15030	COG4555	ABC transporter
NRZ50_15050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NRZ50_15055	COG0735	belongs to the Fur family
NRZ50_15165	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NRZ50_15180	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NRZ50_15190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NRZ50_15200	COG2766	serine protein kinase
NRZ50_15230	COG3620	sequence-specific DNA binding
NRZ50_15265	COG0305	Participates in initiation and elongation during chromosome replication
NRZ50_15355	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NRZ50_15360	COG0582	viral genome integration into host DNA
NRZ50_15490	COG4824	toxin secretion phage lysis holin
NRZ50_15520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ50_15525	COG1126	abc transporter atp-binding protein
NRZ50_15530	COG0765	amino acid transport
NRZ50_15535	COG0765	amino acid transport
NRZ50_15540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NRZ50_15550	COG1585	Membrane protein implicated in regulation of membrane protease activity
NRZ50_15555	COG2268	Band 7 protein
NRZ50_15565	COG3290	protein histidine kinase activity
NRZ50_15570	COG4565	transcriptional regulatory protein
NRZ50_15575	COG2851	Citrate transporter
NRZ50_15595	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NRZ50_15600	COG3842	ATPase activity
NRZ50_15610	COG0395	ABC-type sugar transport system, permease component
NRZ50_15620	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NRZ50_15625	COG0745	RESPONSE REGULATOR receiver
NRZ50_15630	COG5002	protein histidine kinase activity
NRZ50_15640	COG4990	cell redox homeostasis
NRZ50_15650	COG3290	protein histidine kinase activity
NRZ50_15655	COG4565	transcriptional regulatory protein
NRZ50_15660	COG3493	citrate carrier protein
NRZ50_15665	COG0281	malic enzyme
NRZ50_15675	COG0697	spore germination
NRZ50_15680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ50_15690	COG5002	protein histidine kinase activity
NRZ50_15695	COG0745	RESPONSE REGULATOR receiver
NRZ50_15705	COG0454	-acetyltransferase
NRZ50_15705	COG0456	acetyltransferase
NRZ50_15710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NRZ50_15715	COG3383	formate dehydrogenase (NAD+) activity
NRZ50_15720	COG2427	Protein of unknown function (DUF1641)
NRZ50_15735	COG0531	amino acid
NRZ50_15740	COG0640	Transcriptional regulator
NRZ50_15745	COG2217	Heavy metal translocating P-type atpase
NRZ50_15750	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NRZ50_15765	COG3227	Zinc metalloprotease (Elastase)
NRZ50_15785	COG2720	vancomycin resistance protein
NRZ50_15790	COG1316	TRANSCRIPTIONal
NRZ50_15795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ50_15800	COG0346	lactoylglutathione lyase activity
NRZ50_15805	COG1253	flavin adenine dinucleotide binding
NRZ50_15810	COG1027	Aspartate ammonia-lyase
NRZ50_15815	COG1620	l-lactate permease
NRZ50_15830	COG3104	oligopeptide transport
NRZ50_15835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ50_15840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ50_15845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NRZ50_15855	COG2226	methyltransferase
NRZ50_15860	COG0156	8-amino-7-oxononanoate synthase activity
NRZ50_15865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NRZ50_15870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NRZ50_15880	COG4548	von Willebrand factor, type A
NRZ50_15885	COG0714	Associated with various cellular activities
NRZ50_15890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ50_15910	COG0531	amino acid
NRZ50_15915	COG2188	Transcriptional regulator
NRZ50_15920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ50_15920	COG1263	PTS System
NRZ50_15925	COG0366	Alpha amylase catalytic
NRZ50_15940	COG0697	spore germination
NRZ50_15950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NRZ50_15955	COG1115	amino acid carrier protein
NRZ50_15960	COG1126	abc transporter atp-binding protein
NRZ50_15965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ50_15970	COG0765	amino acid transport
NRZ50_15975	COG0765	amino acid transport
NRZ50_15980	COG0833	amino acid
NRZ50_15995	COG1595	DNA-templated transcription, initiation
NRZ50_16005	COG2378	regulation of single-species biofilm formation
NRZ50_16010	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NRZ50_16015	COG5002	protein histidine kinase activity
NRZ50_16030	COG0659	secondary active sulfate transmembrane transporter activity
NRZ50_16035	COG0589	response to stress
NRZ50_16045	COG0747	negative chemotaxis
NRZ50_16055	COG0601	transmembrane transport
NRZ50_16060	COG4608	Belongs to the ABC transporter superfamily
NRZ50_16070	COG2271	Major facilitator Superfamily
NRZ50_16075	COG1846	Transcriptional regulator
NRZ50_16080	COG0477	Major facilitator Superfamily
NRZ50_16085	COG1609	Transcriptional regulator
NRZ50_16090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRZ50_16105	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRZ50_16110	COG1879	ABC-type sugar transport system periplasmic component
NRZ50_16135	COG1063	alcohol dehydrogenase
NRZ50_16150	COG3568	Endonuclease Exonuclease Phosphatase
NRZ50_16180	COG0840	transmembrane signaling receptor activity
NRZ50_16185	COG3583	domain protein
NRZ50_16185	COG3584	3D domain protein
NRZ50_16190	COG1476	TRANSCRIPTIONal
NRZ50_16205	COG3104	oligopeptide transport
NRZ50_16210	COG1114	Component of the transport system for branched-chain amino acids
NRZ50_16215	COG1464	Belongs to the NlpA lipoprotein family
NRZ50_16220	COG1960	acyl-CoA dehydrogenase activity
NRZ50_16225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NRZ50_16230	COG2011	ABC-type metal ion transport system permease component
NRZ50_16245	COG1113	amino acid transport
NRZ50_16250	COG2252	PERMEase
NRZ50_16265	COG2153	protein acetylation
NRZ50_16275	COG0569	domain protein
NRZ50_16275	COG0475	glutathione-regulated potassium exporter activity
NRZ50_16290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NRZ50_16295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NRZ50_16300	COG0833	amino acid
NRZ50_16305	COG4990	cell redox homeostasis
NRZ50_16320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ50_16330	COG0531	amino acid
NRZ50_16345	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NRZ50_16350	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NRZ50_16355	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NRZ50_16355	COG1918	ferrous iron import across plasma membrane
NRZ50_16360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NRZ50_16365	COG0573	inorganic phosphate transmembrane transporter activity
NRZ50_16370	COG0581	inorganic phosphate transmembrane transporter activity
NRZ50_16380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NRZ50_16505	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NRZ50_16525	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NRZ50_16530	COG1116	anion transmembrane transporter activity
NRZ50_16535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ50_16540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NRZ50_16545	COG0352	thiamine-phosphate diphosphorylase activity
NRZ50_16550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ50_16555	COG2104	thiamine diphosphate biosynthetic process
NRZ50_16565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ50_16570	COG0351	phosphomethylpyrimidine kinase
NRZ50_16610	COG2205	protein histidine kinase activity
NRZ50_16615	COG2814	Major facilitator Superfamily
NRZ50_16620	COG1846	Transcriptional regulator
NRZ50_16635	COG2252	PERMEase
NRZ50_16640	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_16645	COG1376	ErfK ybiS ycfS ynhG family protein
NRZ50_16660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ50_16700	COG0778	Nitroreductase
NRZ50_16705	COG2719	SpoVR family
NRZ50_16740	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRZ50_16745	COG1937	Protein conserved in bacteria
NRZ50_16750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ50_16750	COG0425	Belongs to the sulfur carrier protein TusA family
NRZ50_16755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ50_16755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ50_16760	COG0425	Belongs to the sulfur carrier protein TusA family
NRZ50_16770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ50_16780	COG2210	Belongs to the sulfur carrier protein TusA family
NRZ50_16785	COG0730	response to heat
NRZ50_16795	COG1316	TRANSCRIPTIONal
NRZ50_16800	COG0604	alcohol dehydrogenase
NRZ50_16805	COG1283	sodium-dependent phosphate transmembrane transporter activity
NRZ50_16810	COG2814	Major facilitator Superfamily
NRZ50_16820	COG3711	transcriptional antiterminator
NRZ50_16820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRZ50_16825	COG1447	Phosphotransferase system cellobiose-specific component IIA
NRZ50_16830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NRZ50_16850	COG1388	LysM domain
NRZ50_16850	COG3584	3D domain protein
NRZ50_16855	COG0577	efflux transmembrane transporter activity
NRZ50_16860	COG1136	(ABC) transporter
NRZ50_16870	COG5522	Integral membrane protein (intg_mem_TP0381)
NRZ50_16885	COG0577	efflux transmembrane transporter activity
NRZ50_16890	COG1114	Component of the transport system for branched-chain amino acids
NRZ50_16895	COG3546	catalase activity
NRZ50_16930	COG0586	Pfam SNARE associated Golgi protein
NRZ50_16965	COG0531	amino acid
NRZ50_16970	COG0475	glutathione-regulated potassium exporter activity
NRZ50_16980	COG1737	Transcriptional regulator
NRZ50_16990	COG1263	PTS System
NRZ50_16990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ50_17000	COG2259	Doxx family
NRZ50_17020	COG1522	sequence-specific DNA binding
NRZ50_17035	COG2076	Multidrug Resistance protein
NRZ50_17040	COG1309	transcriptional regulator
NRZ50_17045	COG2814	Major facilitator Superfamily
NRZ50_17055	COG1846	Transcriptional regulator
NRZ50_17060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NRZ50_17065	COG0477	Major facilitator Superfamily
NRZ50_17070	COG0657	acetylesterase activity
NRZ50_17080	COG1309	transcriptional regulator
NRZ50_17085	COG2124	cytochrome p450
NRZ50_17095	COG1063	alcohol dehydrogenase
NRZ50_17105	COG1733	regulation of RNA biosynthetic process
NRZ50_17115	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRZ50_17120	COG4533	DNA binding
NRZ50_17125	COG2211	Major facilitator Superfamily
NRZ50_17135	COG0693	protein deglycase activity
NRZ50_17140	COG0753	catalase activity
NRZ50_17150	COG0531	amino acid
NRZ50_17155	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NRZ50_17170	COG1132	(ABC) transporter
NRZ50_17175	COG1132	(ABC) transporter
NRZ50_17180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRZ50_17185	COG0765	amino acid transport
NRZ50_17190	COG1126	abc transporter atp-binding protein
NRZ50_17205	COG0189	ligase activity
NRZ50_17235	COG4585	Histidine kinase
NRZ50_17240	COG2197	response regulator
NRZ50_17280	COG0028	Belongs to the TPP enzyme family
NRZ50_17285	COG3527	Alpha-acetolactate decarboxylase
NRZ50_17295	COG0561	phosphatase activity
NRZ50_17300	COG5632	N-Acetylmuramoyl-L-alanine amidase
NRZ50_17300	COG3409	Peptidoglycan-binding domain 1 protein
NRZ50_17305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NRZ50_17330	COG0659	secondary active sulfate transmembrane transporter activity
NRZ50_17345	COG0653	protein targeting
NRZ50_17350	COG2244	polysaccharide biosynthetic process
NRZ50_17360	COG0860	N-Acetylmuramoyl-L-alanine amidase
NRZ50_17365	COG4196	transglutaminase domain protein
NRZ50_17380	COG1696	Membrane protein involved in D-alanine export
NRZ50_17395	COG1024	Enoyl-CoA hydratase
NRZ50_17415	COG1363	Peptidase, m42
NRZ50_17450	COG0477	Major facilitator Superfamily
NRZ50_17455	COG3290	protein histidine kinase activity
NRZ50_17460	COG4565	transcriptional regulatory protein
NRZ50_17465	COG3181	Tripartite tricarboxylate transporter family receptor
NRZ50_17510	COG4978	Transcriptional regulator
NRZ50_17510	COG0789	Transcriptional regulator
NRZ50_17535	COG0305	Participates in initiation and elongation during chromosome replication
NRZ50_17600	COG3320	Male sterility
NRZ50_17600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NRZ50_17605	COG1309	transcriptional regulator
NRZ50_17620	COG1476	TRANSCRIPTIONal
NRZ50_17630	COG3711	transcriptional antiterminator
NRZ50_17635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRZ50_17635	COG1263	PTS System
NRZ50_17635	COG2190	(PTS) system
NRZ50_17640	COG2723	6-phospho-beta-galactosidase activity
NRZ50_17650	COG1183	phosphatidylcholine synthase activity
NRZ50_17675	COG2376	Dihydroxyacetone kinase
NRZ50_17685	COG2376	Dihydroxyacetone kinase
NRZ50_17735	COG0482	sulfurtransferase activity
NRZ50_17805	COG3237	CsbD-like
NRZ50_17830	COG1191	sigma factor activity
NRZ50_17840	COG2208	phosphoserine phosphatase activity
NRZ50_17845	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NRZ50_17850	COG0784	Response regulator, receiver
NRZ50_17850	COG2205	protein histidine kinase activity
NRZ50_17850	COG2198	Histidine kinase
NRZ50_17915	COG0420	3'-5' exonuclease activity
NRZ50_17920	COG4717	serine-type aminopeptidase activity
NRZ50_17930	COG4974	Belongs to the 'phage' integrase family
NRZ50_17960	COG3646	Phage regulatory protein
NRZ50_18035	COG3331	DNA recombination
NRZ50_18220	COG5444	nuclease activity
NRZ50_18270	COG0346	lactoylglutathione lyase activity
NRZ50_18275	COG0346	lactoylglutathione lyase activity
NRZ50_18285	COG0457	Tetratricopeptide repeat
NRZ50_18295	COG2267	carboxylic ester hydrolase activity
NRZ50_18320	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NRZ50_18325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRZ50_18335	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NRZ50_18355	COG0772	Belongs to the SEDS family
NRZ50_18370	COG0477	Major facilitator Superfamily
NRZ50_18375	COG0477	Major facilitator Superfamily
NRZ50_18385	COG1033	growth of symbiont in host cell
NRZ50_18385	COG2409	Drug exporters of the RND superfamily
NRZ50_18395	COG3973	AAA domain
NRZ50_18400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ50_18420	COG4980	gas vesicle protein
NRZ50_18425	COG0537	adenosine 5'-monophosphoramidase activity
NRZ50_18430	COG1131	(ABC) transporter
NRZ50_18435	COG4473	ABC transporter
NRZ50_18525	COG1309	transcriptional regulator
NRZ50_18535	COG3402	PFAM membrane-flanked domain
NRZ50_18540	COG3428	Bacterial PH domain
NRZ50_18560	COG3402	PFAM membrane-flanked domain
NRZ50_18565	COG3428	Bacterial PH domain
NRZ50_18570	COG2329	Antibiotic biosynthesis monooxygenase
NRZ50_18575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ50_18590	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NRZ50_18625	COG1309	transcriptional regulator
NRZ50_18630	COG1511	domain protein
NRZ50_18660	COG2378	regulation of single-species biofilm formation
NRZ50_18665	COG1609	Transcriptional regulator
NRZ50_18675	COG1234	tRNA 3'-trailer cleavage
NRZ50_18680	COG0095	Lipoate-protein ligase
NRZ50_18690	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ50_18710	COG1408	metallophosphoesterase
NRZ50_18715	COG1078	dGTPase activity
NRZ50_18725	COG0477	Major facilitator Superfamily
NRZ50_18735	COG1595	DNA-templated transcription, initiation
NRZ50_18740	COG3708	Transcriptional regulator
NRZ50_18740	COG2207	Transcriptional regulator
NRZ50_18755	COG2205	protein histidine kinase activity
NRZ50_18760	COG0745	RESPONSE REGULATOR receiver
NRZ50_18785	COG0501	Belongs to the peptidase M48B family
NRZ50_18790	COG0840	transmembrane signaling receptor activity
NRZ50_18795	COG0697	spore germination
NRZ50_18815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NRZ50_18820	COG2224	Isocitrate lyase
NRZ50_18830	COG1278	Cold shock
NRZ50_18845	COG4903	ComK protein
NRZ50_18850	COG0398	Pfam SNARE associated Golgi protein
NRZ50_18910	COG0179	Fumarylacetoacetate (FAA) hydrolase
NRZ50_18935	COG0367	asparagine synthase
NRZ50_18945	COG0753	catalase activity
NRZ50_18950	COG0004	ammonium transporteR
NRZ50_18970	COG2996	Protein conserved in bacteria
NRZ50_18975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ50_18985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ50_19000	COG0561	phosphatase activity
NRZ50_19020	COG2267	carboxylic ester hydrolase activity
NRZ50_19035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ50_19040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NRZ50_19045	COG5504	Zn-dependent protease
NRZ50_19055	COG0180	Tryptophanyl-tRNA synthetase
NRZ50_19065	COG4166	transmembrane transport
NRZ50_19070	COG0601	transmembrane transport
NRZ50_19075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRZ50_19080	COG0444	Belongs to the ABC transporter superfamily
NRZ50_19085	COG4608	Belongs to the ABC transporter superfamily
NRZ50_19090	COG0534	Mate efflux family protein
NRZ50_19095	COG4166	transmembrane transport
NRZ50_19110	COG0861	Integral membrane protein TerC family
NRZ50_19115	COG4862	establishment of competence for transformation
NRZ50_19120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ50_19130	COG1164	Oligoendopeptidase f
NRZ50_19145	COG2346	COG2346, Truncated hemoglobins
NRZ50_19150	COG4116	CYTH
NRZ50_19160	COG2357	RelA SpoT domain protein
NRZ50_19170	COG0564	pseudouridine synthase activity
NRZ50_19185	COG0772	Belongs to the SEDS family
NRZ50_19190	COG0463	Glycosyl transferase, family 2
NRZ50_19190	COG1216	Glycosyl transferase, family 2
NRZ50_19220	COG0463	Glycosyl transferase, family 2
NRZ50_19220	COG0457	Tetratricopeptide repeat
NRZ50_19240	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NRZ50_19255	COG1091	dTDP-4-dehydrorhamnose reductase activity
NRZ50_19300	COG2153	protein acetylation
NRZ50_19310	COG2382	esterase
NRZ50_19325	COG5492	domain, Protein
NRZ50_19330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ50_19340	COG0512	Glutamine amidotransferase of anthranilate synthase
NRZ50_19340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRZ50_19375	COG1620	l-lactate permease
NRZ50_19380	COG5634	Uncharacterized conserved protein (DUF2278)
NRZ50_19435	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRZ50_19445	COG1476	TRANSCRIPTIONal
NRZ50_19520	COG1686	Belongs to the peptidase S11 family
NRZ50_19525	COG0681	Belongs to the peptidase S26 family
NRZ50_19545	COG1396	sequence-specific DNA binding
NRZ50_19560	COG1012	belongs to the aldehyde dehydrogenase family
NRZ50_19570	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRZ50_19575	COG1177	transmembrane transport
NRZ50_19580	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NRZ50_19590	COG2409	Drug exporters of the RND superfamily
NRZ50_19600	COG0564	pseudouridine synthase activity
NRZ50_19610	COG2340	Cysteine-rich secretory protein family
NRZ50_19615	COG0247	lactate metabolic process
NRZ50_19620	COG0277	FAD linked oxidase domain protein
NRZ50_19625	COG3835	regulator
NRZ50_19635	COG0745	RESPONSE REGULATOR receiver
NRZ50_19640	COG5002	protein histidine kinase activity
NRZ50_19645	COG2186	Transcriptional regulator
NRZ50_19665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NRZ50_19675	COG2116	formate transmembrane transporter activity
NRZ50_19680	COG0861	Integral membrane protein TerC family
NRZ50_19685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ50_19695	COG2030	dehydratase
NRZ50_19715	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_19720	COG3243	poly(R)-hydroxyalkanoic acid synthase
NRZ50_19730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ50_19745	COG1840	ABC-type Fe3 transport system, periplasmic component
NRZ50_19750	COG3842	ATPase activity
NRZ50_19775	COG1349	DNA-binding transcription factor activity
NRZ50_19785	COG0235	Class ii aldolase
NRZ50_19795	COG2861	carbohydrate metabolic process
NRZ50_19805	COG3852	Histidine kinase
NRZ50_19810	COG1846	Transcriptional regulator
NRZ50_19820	COG2318	DinB family
NRZ50_19830	COG5002	protein histidine kinase activity
NRZ50_19840	COG0720	synthase
NRZ50_19855	COG4873	Protein conserved in bacteria
NRZ50_19885	COG1780	Probably involved in ribonucleotide reductase function
NRZ50_19900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRZ50_19905	COG1725	Transcriptional regulator
NRZ50_19910	COG1131	(ABC) transporter
NRZ50_19920	COG1131	(ABC) transporter
NRZ50_19925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NRZ50_19930	COG1266	CAAX protease self-immunity
NRZ50_19940	COG1522	sequence-specific DNA binding
NRZ50_19950	COG1335	isochorismatase
NRZ50_19960	COG1619	proteins homologs of microcin C7 resistance protein MccF
NRZ50_19965	COG2070	2-Nitropropane dioxygenase
NRZ50_19970	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NRZ50_19980	COG1696	Membrane protein involved in D-alanine export
NRZ50_20005	COG0716	FMN binding
NRZ50_20020	COG3173	Aminoglycoside phosphotransferase
NRZ50_20040	COG0534	Mate efflux family protein
NRZ50_20060	COG1846	Transcriptional regulator
NRZ50_20070	COG1301	dicarboxylic acid transport
NRZ50_20075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NRZ50_20080	COG4709	membrane
NRZ50_20085	COG3874	Sporulation protein YtfJ
NRZ50_20105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRZ50_20110	COG0028	Belongs to the TPP enzyme family
NRZ50_20115	COG0440	acetolactate synthase activity
NRZ50_20190	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NRZ50_20205	COG1183	phosphatidylcholine synthase activity
NRZ50_20210	COG1368	sulfuric ester hydrolase activity
NRZ50_20220	COG0019	diaminopimelate decarboxylase activity
NRZ50_20240	COG0529	Catalyzes the synthesis of activated sulfate
NRZ50_20245	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRZ50_20265	COG1648	precorrin-2 dehydrogenase activity
NRZ50_20270	COG0733	neurotransmitter:sodium symporter activity
NRZ50_20295	COG1757	Na H antiporter
NRZ50_20310	COG4758	membrane
NRZ50_20315	COG4585	Histidine kinase
NRZ50_20320	COG2197	response regulator
NRZ50_20330	COG1114	Component of the transport system for branched-chain amino acids
NRZ50_20340	COG2226	methyltransferase
NRZ50_20380	COG0730	response to heat
NRZ50_20385	COG0306	phosphate transporter
NRZ50_20390	COG1392	Phosphate transport regulator
NRZ50_20395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ50_20410	COG3852	Histidine kinase
NRZ50_20415	COG1801	Protein of unknown function DUF72
NRZ50_20425	COG0582	viral genome integration into host DNA
NRZ50_20430	COG5002	protein histidine kinase activity
NRZ50_20445	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NRZ50_20445	COG0392	lysyltransferase activity
NRZ50_20460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NRZ50_20465	COG1686	Belongs to the peptidase S11 family
NRZ50_20470	COG2715	membrane protein required for spore maturation
NRZ50_20475	COG0700	Nucleoside recognition
NRZ50_20480	COG1187	pseudouridine synthase activity
NRZ50_20490	COG1333	cytochrome c biogenesis protein
NRZ50_20495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NRZ50_20500	COG0745	RESPONSE REGULATOR receiver
NRZ50_20505	COG5002	protein histidine kinase activity
NRZ50_20510	COG2096	Adenosyltransferase
NRZ50_20515	COG4942	peptidase
NRZ50_20530	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NRZ50_20535	COG1141	Ferredoxin
NRZ50_20545	COG0514	ATP-dependent DNA helicase (RecQ)
NRZ50_20550	COG1266	CAAX protease self-immunity
NRZ50_20560	COG1408	metallophosphoesterase
NRZ50_20570	COG4862	establishment of competence for transformation
NRZ50_20575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NRZ50_20595	COG0492	ferredoxin-NADP+ reductase activity
NRZ50_20670	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NRZ50_20685	COG0142	geranyltranstransferase activity
NRZ50_20695	COG0142	geranyltranstransferase activity
NRZ50_20715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NRZ50_20720	COG0457	Tetratricopeptide repeat
NRZ50_20740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NRZ50_20745	COG2010	Cytochrome c
NRZ50_20745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NRZ50_20750	COG4347	Protein of unknown function (DUF1405)
NRZ50_20765	COG2738	Putative neutral zinc metallopeptidase
NRZ50_20775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ50_20780	COG1694	Mazg nucleotide pyrophosphohydrolase
NRZ50_20795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NRZ50_20800	COG0438	transferase activity, transferring glycosyl groups
NRZ50_20835	COG1199	ATP-dependent helicase activity
NRZ50_20835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NRZ50_20855	COG3935	DnaD domain protein
NRZ50_20860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NRZ50_20870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ50_20870	COG4499	WXG100 protein secretion system (Wss), protein YukC
NRZ50_20930	COG0116	Belongs to the methyltransferase superfamily
NRZ50_20940	COG1199	ATP-dependent helicase activity
NRZ50_20945	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NRZ50_20955	COG0024	Methionine aminopeptidase
NRZ50_20965	COG2233	PERMEase
NRZ50_20970	COG2311	Membrane
NRZ50_20980	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NRZ50_20990	COG0456	acetyltransferase
NRZ50_21025	COG0754	glutathionylspermidine amidase activity
NRZ50_21040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NRZ50_21065	COG3800	Transcriptional regulator
NRZ50_21065	COG1396	sequence-specific DNA binding
NRZ50_21085	COG3645	SOS response
NRZ50_21085	COG3646	Phage regulatory protein
NRZ50_21170	COG4626	Terminase
NRZ50_21170	COG1802	Transcriptional regulator
NRZ50_21245	COG5632	N-Acetylmuramoyl-L-alanine amidase
NRZ50_21315	COG0454	-acetyltransferase
NRZ50_21335	COG0328	RNA-DNA hybrid ribonuclease activity
NRZ50_21370	COG3403	YqcI/YcgG family
NRZ50_21375	COG1280	lysine exporter protein (LysE YggA)
NRZ50_21390	COG3162	membrane
NRZ50_21395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRZ50_21400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NRZ50_21410	COG0475	glutathione-regulated potassium exporter activity
NRZ50_21415	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NRZ50_21420	COG0789	Transcriptional regulator
NRZ50_21420	COG4978	Transcriptional regulator
NRZ50_21430	COG2323	membrane
NRZ50_21435	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NRZ50_21470	COG2814	Major facilitator Superfamily
NRZ50_21480	COG2814	Major facilitator Superfamily
NRZ50_21500	COG1923	regulation of RNA biosynthetic process
NRZ50_21510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NRZ50_21515	COG1360	Flagellar Motor Protein
NRZ50_21520	COG2201	protein-glutamate methylesterase activity
NRZ50_21525	COG0643	Histidine kinase
NRZ50_21525	COG2198	Histidine kinase
NRZ50_21530	COG1776	CheC inhibitor of MCP methylation
NRZ50_21530	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ50_21545	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NRZ50_21565	COG1256	bacterial-type flagellum assembly
NRZ50_21570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ50_21575	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NRZ50_21590	COG1815	bacterial-type flagellum-dependent cell motility
NRZ50_21595	COG1558	bacterial-type flagellum-dependent cell motility
NRZ50_21605	COG1766	The M ring may be actively involved in energy transduction
NRZ50_21610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ50_21620	COG1157	protein secretion by the type III secretion system
NRZ50_21655	COG0835	chemotaxis
NRZ50_21655	COG0784	Response regulator, receiver
NRZ50_21665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ50_21670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NRZ50_21675	COG0741	lytic transglycosylase activity
NRZ50_21685	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ50_21690	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NRZ50_21690	COG1776	CheC inhibitor of MCP methylation
NRZ50_21700	COG1338	Plays a role in the flagellum-specific transport system
NRZ50_21705	COG1987	bacterial-type flagellum assembly
NRZ50_21715	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NRZ50_21720	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NRZ50_21725	COG1419	protein localization to endoplasmic reticulum
NRZ50_21730	COG4786	Flagellar basal body rod
NRZ50_21735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NRZ50_21760	COG1309	transcriptional regulator
NRZ50_21780	COG2329	Antibiotic biosynthesis monooxygenase
NRZ50_21805	COG0583	DNA-binding transcription factor activity
NRZ50_21810	COG3842	ATPase activity
NRZ50_21825	COG1234	tRNA 3'-trailer cleavage
NRZ50_21840	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_21855	COG0406	alpha-ribazole phosphatase activity
NRZ50_21875	COG1846	Transcriptional regulator
NRZ50_21885	COG0367	asparagine synthase
NRZ50_21915	COG1802	Transcriptional regulator
NRZ50_21920	COG0697	spore germination
NRZ50_21925	COG0438	transferase activity, transferring glycosyl groups
NRZ50_21925	COG1216	Glycosyl transferase, family 2
NRZ50_21930	COG1757	Na H antiporter
NRZ50_21940	COG0114	fumarate hydratase activity
NRZ50_21955	COG0534	Mate efflux family protein
NRZ50_21960	COG3340	Belongs to the peptidase S51 family
NRZ50_21980	COG0785	Cytochrome C biogenesis protein
NRZ50_22010	COG2733	membrane
NRZ50_22045	COG1131	(ABC) transporter
NRZ50_22060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ50_22065	COG0528	UMP kinase activity
NRZ50_22075	COG1027	Aspartate ammonia-lyase
NRZ50_22080	COG0281	malic enzyme
NRZ50_22085	COG4191	Histidine kinase
NRZ50_22090	COG0784	Response regulator, receiver
NRZ50_22095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NRZ50_22145	COG1051	belongs to the nudix hydrolase family
NRZ50_22150	COG0860	N-Acetylmuramoyl-L-alanine amidase
NRZ50_22175	COG3842	ATPase activity
NRZ50_22180	COG2508	Transcriptional regulator
NRZ50_22190	COG1175	transmembrane transport
NRZ50_22195	COG0395	ABC-type sugar transport system, permease component
NRZ50_22205	COG2188	Transcriptional regulator
NRZ50_22210	COG2222	sugar isomerase
NRZ50_22225	COG1105	Belongs to the carbohydrate kinase PfkB family
NRZ50_22240	COG1695	Transcriptional regulator
NRZ50_22250	COG0477	Major facilitator Superfamily
NRZ50_22255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ50_22265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NRZ50_22270	COG4166	transmembrane transport
NRZ50_22275	COG2223	nitrite transmembrane transporter activity
NRZ50_22280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NRZ50_22295	COG2244	polysaccharide biosynthetic process
NRZ50_22300	COG0733	neurotransmitter:sodium symporter activity
NRZ50_22310	COG5566	PFAM Mor transcription activator
NRZ50_22315	COG2323	membrane
NRZ50_22330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NRZ50_22340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRZ50_22345	COG0028	Belongs to the TPP enzyme family
NRZ50_22390	COG2814	Major facilitator Superfamily
NRZ50_22395	COG3384	dioxygenase
NRZ50_22405	COG3279	Response regulator of the LytR AlgR family
NRZ50_22410	COG0427	acetyl-CoA hydrolase
NRZ50_22430	COG4166	transmembrane transport
NRZ50_22445	COG0535	radical SAM domain protein
NRZ50_22450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ50_22455	COG0745	RESPONSE REGULATOR receiver
NRZ50_22475	COG1914	H( )-stimulated, divalent metal cation uptake system
NRZ50_22490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NRZ50_22500	COG0531	amino acid
NRZ50_22525	COG2390	Transcriptional regulator
NRZ50_22535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ50_22540	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NRZ50_22550	COG4846	Membrane protein involved in cytochrome C biogenesis
NRZ50_22560	COG0006	proline dipeptidase activity
NRZ50_22580	COG3344	reverse transcriptase
NRZ50_22610	COG1114	Component of the transport system for branched-chain amino acids
NRZ50_22620	COG2372	response to copper ion
NRZ50_22620	COG1276	copper resistance
NRZ50_22625	COG4549	nuclear export factor GLE1
NRZ50_22630	COG0697	spore germination
NRZ50_22635	COG0583	DNA-binding transcription factor activity
NRZ50_22640	COG1959	2 iron, 2 sulfur cluster binding
NRZ50_22645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NRZ50_22650	COG0778	Nitroreductase
NRZ50_22665	COG0628	permease
NRZ50_22675	COG1231	oxidoreductase activity
NRZ50_22680	COG0523	cobalamin synthesis protein
NRZ50_22695	COG0318	PFAM AMP-dependent synthetase and ligase
NRZ50_22700	COG2030	dehydratase
NRZ50_22705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ50_22745	COG1942	4-Oxalocrotonate Tautomerase
NRZ50_22765	COG1271	oxidase subunit
NRZ50_22770	COG1294	oxidase, subunit
NRZ50_22775	COG4988	ABC transporter
NRZ50_22780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NRZ50_22790	COG1216	Glycosyl transferase, family 2
NRZ50_22830	COG1686	Belongs to the peptidase S11 family
NRZ50_22845	COG0791	NLP P60 protein
NRZ50_22845	COG1388	LysM domain
NRZ50_22855	COG1132	(ABC) transporter
NRZ50_22860	COG0745	RESPONSE REGULATOR receiver
NRZ50_22865	COG5002	protein histidine kinase activity
NRZ50_22870	COG0300	oxidoreductase activity
NRZ50_22875	COG4122	O-methyltransferase activity
NRZ50_22890	COG5658	integral membrane protein
NRZ50_22905	COG0460	homoserine dehydrogenase
NRZ50_22930	COG1316	TRANSCRIPTIONal
NRZ50_22950	COG1285	pathogenesis
NRZ50_22955	COG1247	-acetyltransferase
NRZ50_22965	COG2814	Major facilitator Superfamily
NRZ50_22970	COG1279	arginine transmembrane transporter activity
NRZ50_22975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ50_22985	COG1752	Esterase of the alpha-beta hydrolase superfamily
NRZ50_23020	COG0577	efflux transmembrane transporter activity
NRZ50_23025	COG2002	toxin-antitoxin pair type II binding
NRZ50_23030	COG1404	Belongs to the peptidase S8 family
NRZ50_23035	COG0640	Transcriptional regulator
NRZ50_23040	COG0667	Aldo Keto reductase
NRZ50_23085	COG3949	Membrane
NRZ50_23090	COG0783	Belongs to the Dps family
NRZ50_23105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NRZ50_23115	COG1231	oxidoreductase activity
NRZ50_23120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ50_23125	COG4989	oxidoreductase activity
NRZ50_23130	COG0523	cobalamin synthesis protein
NRZ50_23135	COG0456	acetyltransferase
NRZ50_23140	COG0803	Belongs to the bacterial solute-binding protein 9 family
NRZ50_23140	COG3443	Belongs to the bacterial solute-binding protein 9 family
NRZ50_23150	COG0702	epimerase
NRZ50_23160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NRZ50_23170	COG4166	transmembrane transport
NRZ50_23185	COG0406	alpha-ribazole phosphatase activity
NRZ50_23195	COG5337	Spore coat protein CotH
NRZ50_23200	COG1051	belongs to the nudix hydrolase family
NRZ50_23205	COG0586	Pfam SNARE associated Golgi protein
NRZ50_23210	COG2244	polysaccharide biosynthetic process
NRZ50_23220	COG0701	Predicted permease
NRZ50_23225	COG3689	TIGRFAM TIGR03943 family protein
NRZ50_23230	COG1607	acyl-coa hydrolase
NRZ50_23240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ50_23255	COG0702	epimerase
NRZ50_23260	COG2839	Protein conserved in bacteria
NRZ50_23265	COG1253	flavin adenine dinucleotide binding
NRZ50_23280	COG1114	Component of the transport system for branched-chain amino acids
NRZ50_23285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ50_23305	COG0860	N-Acetylmuramoyl-L-alanine amidase
NRZ50_23315	COG1876	peptidase activity
NRZ50_23325	COG0154	amidase activity
NRZ50_23330	COG2211	Major facilitator Superfamily
NRZ50_23345	COG2368	4-hydroxyphenylacetate
NRZ50_23355	COG0196	riboflavin kinase activity
NRZ50_23370	COG0251	oxidation-reduction process
NRZ50_23380	COG3971	2-oxopent-4-enoate hydratase activity
NRZ50_23410	COG0561	phosphatase activity
NRZ50_23420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRZ50_23425	COG4106	trans-aconitate 2-methyltransferase activity
NRZ50_23440	COG1819	glycosyl
NRZ50_23445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NRZ50_23450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ50_23480	COG0456	acetyltransferase
NRZ50_23555	COG3874	Sporulation protein YtfJ
NRZ50_23580	COG2226	methyltransferase
NRZ50_23605	COG0346	lactoylglutathione lyase activity
NRZ50_23615	COG0604	alcohol dehydrogenase
NRZ50_23620	COG1595	DNA-templated transcription, initiation
NRZ50_23640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NRZ50_23640	COG0426	domain, Protein
NRZ50_23650	COG0386	Belongs to the glutathione peroxidase family
NRZ50_23660	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NRZ50_23665	COG0714	Associated with various cellular activities
NRZ50_23680	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NRZ50_23685	COG1140	nitrate reductase beta subunit
NRZ50_23690	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NRZ50_23695	COG2181	nitrate reductase activity
NRZ50_23700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRZ50_23705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NRZ50_23710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRZ50_23715	COG0303	'Molybdopterin
NRZ50_23720	COG0314	molybdopterin synthase activity
NRZ50_23730	COG2223	nitrite transmembrane transporter activity
NRZ50_23750	COG1648	precorrin-2 dehydrogenase activity
NRZ50_23760	COG1587	Uroporphyrinogen-III synthase
NRZ50_23760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NRZ50_23765	COG2146	nitrite reductase [NAD(P)H] activity
NRZ50_23770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NRZ50_23775	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
NRZ50_23810	COG2359	stage V sporulation protein S
NRZ50_23845	COG1418	mRNA catabolic process
NRZ50_23850	COG0488	(ABC) transporter
NRZ50_23865	COG0629	single-stranded DNA binding
NRZ50_23870	COG1413	lyase activity
NRZ50_23885	COG2521	methyltransferase
NRZ50_23885	COG2136	Putative SAM-dependent methyltransferase
NRZ50_23925	COG0017	Asparaginyl-tRNA synthetase
NRZ50_23945	COG1674	ftsk spoiiie
NRZ50_24005	COG0733	neurotransmitter:sodium symporter activity
NRZ50_24030	COG2610	gluconate transmembrane transporter activity
NRZ50_24035	COG1454	alcohol dehydrogenase
NRZ50_24040	COG1794	racemase activity, acting on amino acids and derivatives
NRZ50_24050	COG0456	acetyltransferase
NRZ50_24055	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NRZ50_24065	COG1131	(ABC) transporter
NRZ50_24070	COG4473	ABC transporter
NRZ50_24080	COG0546	phosphoglycolate phosphatase activity
NRZ50_24100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NRZ50_24120	COG0768	penicillin binding
NRZ50_24130	COG0204	Acyl-transferase
NRZ50_24135	COG1272	protein, Hemolysin III
NRZ50_24145	COG0805	protein transport
NRZ50_24155	COG1307	EDD domain protein, DegV family
NRZ50_24160	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NRZ50_24165	COG1999	signal sequence binding
NRZ50_24170	COG0071	Belongs to the small heat shock protein (HSP20) family
NRZ50_24175	COG0367	asparagine synthase
NRZ50_24195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NRZ50_24200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRZ50_24220	COG1335	isochorismatase
NRZ50_24225	COG1051	belongs to the nudix hydrolase family
NRZ50_24230	COG0071	Belongs to the small heat shock protein (HSP20) family
NRZ50_24235	COG0668	transmembrane transport
NRZ50_24240	COG4585	Histidine kinase
NRZ50_24240	COG2203	Gaf domain
NRZ50_24245	COG2197	response regulator
NRZ50_24255	COG1064	alcohol dehydrogenase
NRZ50_24315	COG0517	IMP dehydrogenase activity
NRZ50_24315	COG1125	glycine betaine transport
NRZ50_24320	COG1174	glycine betaine transport
NRZ50_24355	COG1253	flavin adenine dinucleotide binding
NRZ50_24360	COG1012	belongs to the aldehyde dehydrogenase family
NRZ50_24365	COG5506	Protein of unknown function (DUF1694)
NRZ50_24380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NRZ50_24385	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NRZ50_24390	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NRZ50_24395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRZ50_24400	COG0456	acetyltransferase
NRZ50_24405	COG3829	transcription factor binding
NRZ50_24410	COG1509	lysine 2,3-aminomutase activity
NRZ50_24445	COG4991	sh3 domain protein
NRZ50_24445	COG0515	serine threonine protein kinase
NRZ50_24445	COG3064	Membrane
NRZ50_24450	COG4326	sporulation control protein
NRZ50_24455	COG0671	phosphoesterase, PA-phosphatase related
NRZ50_24460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NRZ50_24465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NRZ50_24475	COG5484	DNA packaging
NRZ50_24475	COG3728	DNA packaging
NRZ50_24510	COG1595	DNA-templated transcription, initiation
NRZ50_24540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NRZ50_24585	COG4499	WXG100 protein secretion system (Wss), protein YukC
NRZ50_24585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRZ50_24595	COG2814	Major facilitator Superfamily
NRZ50_24605	COG0372	Belongs to the citrate synthase family
NRZ50_24610	COG2079	MmgE PrpD family protein
NRZ50_24615	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NRZ50_24620	COG1960	acyl-CoA dehydrogenase activity
NRZ50_24625	COG2084	Dehydrogenase
NRZ50_24635	COG1280	lysine exporter protein (LysE YggA)
NRZ50_24640	COG1024	Enoyl-CoA hydratase
NRZ50_24655	COG0420	3'-5' exonuclease activity
NRZ50_24685	COG2223	nitrite transmembrane transporter activity
NRZ50_24690	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_24695	COG1169	isochorismate synthase
NRZ50_24700	COG1021	2,3-dihydroxybenzoate-AMP ligase
NRZ50_24705	COG1535	isochorismatase
NRZ50_24705	COG3433	isochorismatase activity
NRZ50_24710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NRZ50_24715	COG3251	PFAM MbtH domain protein
NRZ50_24720	COG2814	Major facilitator Superfamily
NRZ50_24755	COG2318	DinB family
NRZ50_24765	COG1115	amino acid carrier protein
NRZ50_24780	COG2329	Antibiotic biosynthesis monooxygenase
NRZ50_24785	COG1187	pseudouridine synthase activity
NRZ50_24790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NRZ50_24800	COG1136	(ABC) transporter
NRZ50_24810	COG2814	Major facilitator Superfamily
NRZ50_24825	COG0028	Belongs to the TPP enzyme family
NRZ50_24880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ50_24910	COG1247	-acetyltransferase
NRZ50_24940	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NRZ50_24955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ50_24965	COG1278	Cold shock
NRZ50_24990	COG1846	Transcriptional regulator
NRZ50_24995	COG2814	Major facilitator Superfamily
NRZ50_25000	COG0583	DNA-binding transcription factor activity
NRZ50_25005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NRZ50_25020	COG0583	DNA-binding transcription factor activity
NRZ50_25025	COG2258	MOSC domain
NRZ50_25040	COG1132	(ABC) transporter
NRZ50_25045	COG1132	(ABC) transporter
NRZ50_25060	COG1396	sequence-specific DNA binding
NRZ50_25095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRZ50_25105	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
NRZ50_25110	COG1595	DNA-templated transcription, initiation
NRZ50_25140	COG1649	PFAM Uncharacterised BCR, COG1649
NRZ50_25165	COG2971	BadF BadG BcrA BcrD
NRZ50_25200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ50_25230	COG1309	transcriptional regulator
NRZ50_25245	COG1136	(ABC) transporter
NRZ50_25245	COG0577	efflux transmembrane transporter activity
NRZ50_25250	COG0500	methyltransferase
NRZ50_25250	COG3615	Tellurite resistance protein tehB
NRZ50_25260	COG2226	methyltransferase
NRZ50_25265	COG3961	Belongs to the TPP enzyme family
NRZ50_25270	COG1846	Transcriptional regulator
NRZ50_25300	COG2195	Cleaves the N-terminal amino acid of tripeptides
NRZ50_25310	COG1595	DNA-templated transcription, initiation
NRZ50_25320	COG0768	penicillin binding
NRZ50_25325	COG0768	penicillin binding
NRZ50_25340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NRZ50_25340	COG2755	lipolytic protein G-D-S-L family
NRZ50_25395	COG0531	amino acid
NRZ50_25430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ50_25430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRZ50_25445	COG1131	(ABC) transporter
NRZ50_25455	COG1309	transcriptional regulator
NRZ50_25480	COG1960	acyl-CoA dehydrogenase activity
NRZ50_25485	COG0439	Biotin carboxylase
NRZ50_25490	COG0511	ligase activity, forming carbon-carbon bonds
NRZ50_25495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NRZ50_25500	COG1024	Enoyl-CoA hydratase
NRZ50_25505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NRZ50_25510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NRZ50_25520	COG1247	-acetyltransferase
NRZ50_25525	COG0572	uridine kinase
NRZ50_25530	COG0596	Alpha beta hydrolase
NRZ50_25535	COG2318	DinB family
NRZ50_25540	COG1686	Belongs to the peptidase S11 family
NRZ50_25565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NRZ50_25570	COG2910	NAD(P)H-binding
NRZ50_25585	COG3227	Zinc metalloprotease (Elastase)
NRZ50_25640	COG3386	PFAM SMP-30 Gluconolaconase
NRZ50_25650	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
NRZ50_25655	COG3773	Cell wall hydrolase
NRZ50_25665	COG0745	RESPONSE REGULATOR receiver
NRZ50_25670	COG2205	protein histidine kinase activity
NRZ50_25680	COG0488	(ABC) transporter
NRZ50_25685	COG1136	(ABC) transporter
NRZ50_25690	COG0577	efflux transmembrane transporter activity
NRZ50_25710	COG0460	homoserine dehydrogenase
NRZ50_25715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ50_25725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NRZ50_25800	COG2124	cytochrome p450
NRZ50_25835	COG0561	phosphatase activity
NRZ50_25840	COG5002	protein histidine kinase activity
NRZ50_25845	COG0768	penicillin binding
NRZ50_25850	COG1819	glycosyl
NRZ50_25855	COG1794	racemase activity, acting on amino acids and derivatives
NRZ50_25880	COG2205	protein histidine kinase activity
NRZ50_25890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NRZ50_25895	COG0604	alcohol dehydrogenase
NRZ50_25900	COG0671	phosphoesterase, PA-phosphatase related
NRZ50_25905	COG0768	penicillin binding
NRZ50_25915	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_25960	COG0693	protein deglycase activity
NRZ50_26015	COG0584	glycerophosphoryl diester phosphodiesterase
NRZ50_26030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ50_26035	COG0697	spore germination
NRZ50_26055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NRZ50_26070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NRZ50_26080	COG2223	nitrite transmembrane transporter activity
NRZ50_26125	COG3878	Protein conserved in bacteria
NRZ50_26145	COG4667	esterase of the alpha-beta hydrolase superfamily
NRZ50_26185	COG0322	excinuclease ABC activity
NRZ50_26225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ50_26255	COG1011	Hydrolase
NRZ50_26275	COG1523	belongs to the glycosyl hydrolase 13 family
NRZ50_26280	COG3227	Zinc metalloprotease (Elastase)
NRZ50_26300	COG0346	lactoylglutathione lyase activity
NRZ50_26305	COG0201	protein transport
NRZ50_26315	COG0697	spore germination
NRZ50_26320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ50_26355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRZ50_26370	COG2959	enzyme of heme biosynthesis
NRZ50_26405	COG3844	kynureninase activity
NRZ50_26410	COG1309	transcriptional regulator
NRZ50_26445	COG3284	Transcriptional regulator
NRZ50_26465	COG1349	DNA-binding transcription factor activity
NRZ50_26480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRZ50_26485	COG0508	dehydrogenase complex catalyzes the overall conversion of
NRZ50_26490	COG0022	dehydrogenase e1 component
NRZ50_26495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NRZ50_26505	COG1028	Short-chain dehydrogenase reductase Sdr
NRZ50_26510	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NRZ50_26510	COG0456	acetyltransferase
NRZ50_26550	COG4176	ABC-type proline glycine betaine transport system permease component
NRZ50_26555	COG4175	Glycine betaine
NRZ50_26555	COG0517	IMP dehydrogenase activity
NRZ50_26585	COG2153	protein acetylation
NRZ50_26590	COG3397	chitin binding
NRZ50_26595	COG1819	glycosyl
NRZ50_26615	COG2205	protein histidine kinase activity
NRZ50_26620	COG2226	methyltransferase
NRZ50_26625	COG2315	Protein conserved in bacteria
NRZ50_26635	COG0658	competence protein
NRZ50_26635	COG2333	competence protein COMEC
NRZ50_26680	COG3973	AAA domain
NRZ50_26695	COG2105	PFAM AIG2 family protein
NRZ50_26700	COG0514	ATP-dependent DNA helicase (RecQ)
NRZ50_26735	COG4637	Psort location Cytoplasmic, score
NRZ50_26755	COG3397	chitin binding
NRZ50_26770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NRZ50_26775	COG1115	amino acid carrier protein
NRZ50_26780	COG1012	belongs to the aldehyde dehydrogenase family
NRZ50_26785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRZ50_26795	COG3938	Belongs to the proline racemase family
NRZ50_26800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NRZ50_26850	COG1078	dGTPase activity
NRZ50_26855	COG0586	Pfam SNARE associated Golgi protein
NRZ50_26870	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NRZ50_26875	COG0519	Catalyzes the synthesis of GMP from XMP
NRZ50_26880	COG4166	transmembrane transport
NRZ50_26890	COG4948	Mandelate Racemase Muconate Lactonizing
NRZ50_26940	COG2936	dipeptidyl-peptidase activity
NRZ50_26945	COG5002	protein histidine kinase activity
NRZ50_26950	COG0745	RESPONSE REGULATOR receiver
NRZ50_26985	COG1164	Oligoendopeptidase f
NRZ50_26990	COG0531	amino acid
NRZ50_26995	COG1522	sequence-specific DNA binding
NRZ50_27000	COG1307	EDD domain protein, DegV family
NRZ50_27045	COG2814	Major facilitator Superfamily
NRZ50_27055	COG1664	Polymer-forming cytoskeletal
NRZ50_27060	COG0789	Transcriptional regulator
NRZ50_27065	COG4533	DNA binding
NRZ50_27070	COG2814	Major facilitator Superfamily
NRZ50_27070	COG0477	Major facilitator Superfamily
NRZ50_27090	COG2261	transglycosylase associated protein
NRZ50_27105	COG2226	methyltransferase
NRZ50_27140	COG0436	Aminotransferase
NRZ50_27145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NRZ50_27170	COG1131	(ABC) transporter
NRZ50_27220	COG0628	permease
NRZ50_27235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NRZ50_27240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ50_27245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NRZ50_27290	COG2746	aminoglycoside 3-N-acetyltransferase activity
NRZ50_27310	COG0697	spore germination
NRZ50_27315	COG2318	DinB family
NRZ50_27335	COG4912	Dna alkylation repair
NRZ50_27350	COG0861	Integral membrane protein TerC family
NRZ50_27355	COG1368	sulfuric ester hydrolase activity
NRZ50_27360	COG0488	(ABC) transporter
NRZ50_27455	COG4974	Belongs to the 'phage' integrase family
NRZ50_27465	COG1033	growth of symbiont in host cell
NRZ50_27465	COG2409	Drug exporters of the RND superfamily
NRZ50_27470	COG1309	transcriptional regulator
NRZ50_27485	COG0287	Prephenate dehydrogenase
NRZ50_27500	COG1605	Chorismate mutase
NRZ50_27500	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NRZ50_27535	COG3584	3D domain protein
NRZ50_27535	COG1388	LysM domain
NRZ50_27545	COG2814	Major facilitator Superfamily
NRZ50_27550	COG1309	transcriptional regulator
NRZ50_27570	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRZ50_27575	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRZ50_27585	COG2390	Transcriptional regulator
NRZ50_27625	COG2329	Antibiotic biosynthesis monooxygenase
NRZ50_27640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NRZ50_27655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRZ50_27660	COG4187	Peptidase family M20/M25/M40
NRZ50_27665	COG1414	Transcriptional regulator
NRZ50_27670	COG0833	amino acid
NRZ50_27675	COG1690	Belongs to the RtcB family
NRZ50_27680	COG3239	Fatty acid desaturase
NRZ50_27690	COG1785	Belongs to the alkaline phosphatase family
NRZ50_27700	COG3655	Transcriptional regulator
NRZ50_27715	COG4377	Putative membrane peptidase family (DUF2324)
NRZ50_27725	COG3279	Response regulator of the LytR AlgR family
NRZ50_27740	COG0346	lactoylglutathione lyase activity
NRZ50_27765	COG0714	Associated with various cellular activities
NRZ50_27785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NRZ50_27790	COG0753	catalase activity
NRZ50_27795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRZ50_27800	COG1116	anion transmembrane transporter activity
NRZ50_27815	COG1846	Transcriptional regulator
NRZ50_27820	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NRZ50_27830	COG1280	lysine exporter protein (LysE YggA)
NRZ50_27835	COG3403	YqcI/YcgG family
NRZ50_27865	COG0714	Associated with various cellular activities
NRZ50_27875	COG0778	Nitroreductase
NRZ50_27880	COG1846	Transcriptional regulator
NRZ50_27920	COG2207	Transcriptional regulator
NRZ50_27925	COG0456	acetyltransferase
NRZ50_27945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRZ50_27990	COG0730	response to heat
NRZ50_28000	COG0833	amino acid
NRZ50_28010	COG4335	DNA alkylation repair
NRZ50_28050	COG0768	penicillin binding
NRZ50_28085	COG1984	allophanate hydrolase subunit 2
NRZ50_28090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NRZ50_28095	COG1414	Transcriptional regulator
NRZ50_28110	COG3142	Participates in the control of copper homeostasis
NRZ50_28115	COG0860	N-Acetylmuramoyl-L-alanine amidase
NRZ50_28120	COG0640	Transcriptional regulator
NRZ50_28135	COG1960	acyl-CoA dehydrogenase activity
NRZ50_28150	COG3314	Sporulation integral membrane protein YlbJ
NRZ50_28170	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NRZ50_28185	COG3848	Pyruvate phosphate dikinase
NRZ50_28185	COG0574	Belongs to the PEP-utilizing enzyme family
NRZ50_28195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NRZ50_28215	COG1063	alcohol dehydrogenase
NRZ50_28255	COG0702	epimerase
NRZ50_28690	COG3344	reverse transcriptase
NRZ50_28750	COG2311	Membrane
NRZ50_28770	COG0457	Tetratricopeptide repeat
NRZ50_28825	COG0702	epimerase
NRZ50_28880	COG2002	toxin-antitoxin pair type II binding
NRZ50_28885	COG4166	transmembrane transport
NRZ50_28905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NRZ50_28990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NRZ50_28995	COG2323	membrane
NRZ50_29015	COG0582	viral genome integration into host DNA
NRZ50_29030	COG3655	Transcriptional regulator
NRZ50_29045	COG1733	regulation of RNA biosynthetic process
NRZ50_29055	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NRZ50_29065	COG1181	Belongs to the D-alanine--D-alanine ligase family
NRZ50_29065	COG2918	glutathione biosynthetic process
NRZ50_29115	COG0463	Glycosyl transferase, family 2
NRZ50_29150	COG0860	N-Acetylmuramoyl-L-alanine amidase
NRZ50_29195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ50_29210	COG2323	membrane
NRZ50_29235	COG0697	spore germination
NRZ50_29290	COG4974	Belongs to the 'phage' integrase family
NRZ50_29305	COG1183	phosphatidylcholine synthase activity
NRZ50_29325	COG0457	Tetratricopeptide repeat
NRZ50_29385	COG0210	DNA helicase
NRZ50_29410	COG0457	Tetratricopeptide repeat
NRZ50_29420	COG1045	serine acetyltransferase
NRZ50_29430	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NRZ50_29445	COG0456	acetyltransferase
NRZ50_29455	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NRZ50_29465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ50_29465	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NRZ50_29475	COG0745	RESPONSE REGULATOR receiver
NRZ50_29480	COG1522	sequence-specific DNA binding
NRZ50_29485	COG0531	amino acid
NRZ50_29525	COG3344	reverse transcriptase
NRZ50_29645	COG0640	Transcriptional regulator
NRZ50_29705	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NRZ50_29720	COG0494	nUDIX hydrolase
NRZ50_29725	COG2368	4-hydroxyphenylacetate
NRZ50_29730	COG1475	DNA binding
NRZ50_29735	COG1611	Belongs to the LOG family
NRZ50_29740	COG3238	Protein conserved in bacteria
NRZ50_29745	COG0167	dihydroorotate dehydrogenase activity
NRZ50_29760	COG0546	phosphoglycolate phosphatase activity
NRZ50_29820	COG1131	(ABC) transporter
NRZ50_29870	COG0463	Glycosyl transferase, family 2
NRZ50_29935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NRZ50_29950	COG2323	membrane
NRZ50_29975	COG0697	spore germination
NRZ50_30230	COG1923	regulation of RNA biosynthetic process
NRZ50_30325	COG0756	dUTP diphosphatase activity
NRZ50_30330	COG0756	dUTP diphosphatase activity
NRZ50_30375	COG0305	Participates in initiation and elongation during chromosome replication
NRZ50_30395	COG3723	Recombinational DNA repair protein, rece pathway
NRZ50_30400	COG5377	YqaJ viral recombinase family
NRZ50_30490	COG1192	Involved in chromosome partitioning
NRZ50_30530	COG0322	excinuclease ABC activity
NRZ50_30635	COG4653	Phage capsid family
NRZ50_30640	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NRZ50_30650	COG2369	cell adhesion
NRZ50_30655	COG5518	Phage portal protein
NRZ50_30675	COG3728	DNA packaging
NRZ50_30675	COG5484	DNA packaging
NRZ50_30685	COG0322	excinuclease ABC activity
NRZ50_30910	COG3654	unkown
NRZ50_30920	COG0662	Cupin 2, conserved barrel domain protein
NRZ50_30965	COG2002	toxin-antitoxin pair type II binding