locus-tag class description GQZ26_00005 ENOG4105VZ8 Transcriptional regulator GQZ26_00010 ENOG4107D63 GQZ26_00025 ENOG4105DUX Transporter GQZ26_00045 ENOG4105C85 amino acid GQZ26_00050 ENOG4105C7N Xanthine uracil vitamin C permease GQZ26_00065 ENOG4105MA6 gCN5-related N-acetyltransferase GQZ26_00090 ENOG4105BZ9 Cytochrome C oxidase, subunit I GQZ26_00095 ENOG4105E2S oxidase) subunit II GQZ26_00115 ENOG4106CAD Protein of unknown function (DUF3311) GQZ26_00120 ENOG4105E1V na solute symporter GQZ26_00140 ENOG4105CE1 Ferrous iron transport protein b GQZ26_00145 ENOG4105CE1 Ferrous iron transport protein b GQZ26_00150 ENOG4105CE1 Ferrous iron transport protein b GQZ26_00155 ENOG4105CVA phosphate GQZ26_00160 ENOG4105C8U phosphate abc transporter GQZ26_00165 ENOG4105E2Z phosphate ABC transporter (Permease GQZ26_00290 ENOG41080XQ Signal transduction protein with cbs domains GQZ26_00310 ENOG4105ETU transcriptional activator (TenA GQZ26_00320 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component GQZ26_00330 ENOG4108VEU Thiamine monophosphate synthase GQZ26_00335 ENOG41080HI glycine oxidase GQZ26_00350 ENOG4105D06 uba thif-type nad fad binding protein GQZ26_00355 ENOG4105DWF phosphomethylpyrimidine kinase GQZ26_00405 ENOG4108INS Transcriptional regulator GQZ26_00430 ENOG4105C19 ABC transporter GQZ26_00440 ENOG4105F5R ABC transporter GQZ26_00445 ENOG4105C2J ABC transporter GQZ26_00450 ENOG4108QGH periplasmic GQZ26_00455 ENOG4105C7N Xanthine uracil vitamin C permease GQZ26_00465 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GQZ26_00485 ENOG4105C5Y PTS System GQZ26_00520 ENOG4108B31 Spore germination protein GQZ26_00545 ENOG4107Y03 Nitroreductase GQZ26_00550 ENOG4105ED1 spovr family GQZ26_00580 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase GQZ26_00585 ENOG4105XTG Pfam:DUF156 GQZ26_00590 ENOG4105VFE sira family GQZ26_00595 ENOG4107TPS domain protein GQZ26_00600 ENOG4105VFE sira family GQZ26_00605 ENOG4105VFE sira family GQZ26_00610 ENOG4105VFE sira family GQZ26_00620 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase GQZ26_00625 ENOG41087NI Sulfite exporter TauE/SafE GQZ26_00635 ENOG4108KGH TRANSCRIPTIONal GQZ26_00660 ENOG4105EMD TRANSCRIPTIONal GQZ26_00665 ENOG4105VCP PTS System GQZ26_00670 ENOG4105VZJ PTS System GQZ26_00695 ENOG41069ER domain protein GQZ26_00700 ENOG4107RBB ABC transporter, permease GQZ26_00705 ENOG4105C19 ABC transporter GQZ26_00735 ENOG4105WEF catalase GQZ26_00770 ENOG4107T5V SNARE associated Golgi GQZ26_00800 ENOG4105CUB amino acid GQZ26_00805 ENOG4107RWR Sodium hydrogen exchanger GQZ26_00815 ENOG4106KNT transcriptional regulator GQZ26_00855 ENOG4108YXU transcriptional regulator AsnC family GQZ26_00865 ENOG4105KPY Small multidrug resistance protein GQZ26_00870 ENOG4105KPY Small multidrug resistance protein GQZ26_00890 ENOG41082F9 transcriptional regulator GQZ26_00895 ENOG41061H0 Monooxygenase GQZ26_00900 ENOG4105C0R drug resistance transporter emrb qaca subfamily GQZ26_00920 ENOG4106A3M Cytochrome p-450 GQZ26_00945 ENOG4105EWC Purine nucleoside phosphorylase GQZ26_00955 ENOG4105K8R UPF0145 protein GQZ26_00965 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_00985 ENOG4105NF4 modulator of drug activity GQZ26_00990 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) GQZ26_00995 ENOG4105E5W Transporter GQZ26_01005 ENOG4107RKG DJ-1/PfpI family GQZ26_01015 ENOG4105D5Q Arginine ornithine antiporter GQZ26_01020 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) GQZ26_01025 ENOG4105C26 Dehydrogenase GQZ26_01030 ENOG4105BZ1 (ABC) transporter GQZ26_01035 ENOG4105BZ1 (ABC) transporter GQZ26_01045 ENOG4105DRP amino acid AbC transporter GQZ26_01050 ENOG4105CDA abc transporter atp-binding protein GQZ26_01065 ENOG410839P GQZ26_01100 ENOG4107FQX Alpha-acetolactate decarboxylase GQZ26_01115 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase GQZ26_01120 ENOG4105D4P Coproporphyrinogen iii oxidase GQZ26_01140 ENOG4105CHH sulfate transporter GQZ26_01180 ENOG4106AKK s-layer domain-containing protein GQZ26_01190 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein GQZ26_01210 ENOG4105CGU Enoyl-CoA hydratase GQZ26_01245 ENOG4105DER m42 family GQZ26_01310 ENOG4108MRH transcriptional regulatory protein GQZ26_01405 ENOG4105CDU Replicative dna helicase GQZ26_01425 ENOG4105C0R drug resistance transporter emrb qaca subfamily GQZ26_01495 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase GQZ26_01510 ENOG4105CMT Dihydroxyacetone kinase GQZ26_01520 ENOG4105CMT Dihydroxyacetone kinase GQZ26_01540 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase GQZ26_01635 ENOG4105WN5 stage II sporulation protein GQZ26_01645 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GQZ26_01655 ENOG4108MJI response regulator GQZ26_01660 ENOG4105BZU Histidine kinase GQZ26_01665 ENOG4105BZU Histidine kinase GQZ26_01685 ENOG4105K8R UPF0145 protein GQZ26_01725 ENOG4107VRP DNA repair exonuclease GQZ26_01730 ENOG4106D4I domain protein GQZ26_01740 ENOG4108IND Tetr family transcriptional regulator GQZ26_01745 ENOG4105EQ0 Major Facilitator superfamily GQZ26_01765 ENOG4108MUZ hydrolase GQZ26_01795 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator GQZ26_01810 ENOG4105C6V Glycerol-3-phosphate dehydrogenase GQZ26_01820 ENOG4105EMN RNA polymerase sigma factor GQZ26_01830 ENOG4105CNI cell division protein FtsW GQZ26_01840 ENOG4105EEM helicase GQZ26_01845 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) GQZ26_01870 ENOG4105K59 histidine triad (HIT) protein GQZ26_01900 ENOG410905X membrane-flanked domain protein GQZ26_01905 ENOG4105CKV Membrane GQZ26_01935 ENOG410905X membrane-flanked domain protein GQZ26_01940 ENOG4105CKV Membrane GQZ26_01945 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation GQZ26_01950 ENOG4105BZ4 penicillin-binding protein GQZ26_01960 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) GQZ26_01965 ENOG4105C1Q protoporphyrinogen oxidase GQZ26_02035 ENOG4106AXD GQZ26_02040 ENOG4108RQ5 Beta-lactamase domain-containing protein GQZ26_02045 ENOG4105DF9 Lipoate-protein, ligase GQZ26_02055 ENOG4105CEY Amp-dependent synthetase and ligase GQZ26_02070 ENOG4105CNA YD repeat protein GQZ26_02130 ENOG4105ENX hydrolase GQZ26_02135 ENOG4107RN3 metallophosphoesterase GQZ26_02145 ENOG4107TVP HD domain protein GQZ26_02155 ENOG4108AEY RNA polymerase sigma factor GQZ26_02160 ENOG41086D8 Transcriptional regulator GQZ26_02175 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GQZ26_02220 ENOG4105ZU5 s-layer protein GQZ26_02225 ENOG4107QP3 malate synthase g GQZ26_02240 ENOG4105VEQ Cold shock protein GQZ26_02255 ENOG4105XVF Competence transcription factor GQZ26_02325 ENOG4105ERH Fumarylacetoacetate hydrolase GQZ26_02350 ENOG4105CAQ asparagine synthetase GQZ26_02360 ENOG4105CH6 catalase GQZ26_02385 ENOG4105QNR S1 RNA binding domain protein GQZ26_02390 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) GQZ26_02400 ENOG4107AYK membrAne GQZ26_02405 ENOG41073B9 GQZ26_02415 ENOG4108KP7 hydrolase GQZ26_02450 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) GQZ26_02455 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) GQZ26_02470 ENOG4105C31 Tryptophanyl-tRNA synthetase GQZ26_02485 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GQZ26_02490 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GQZ26_02500 ENOG4108JQ7 (ABC) transporter GQZ26_02505 ENOG4105UQX Mate efflux family protein GQZ26_02525 ENOG4108ZCF integral membrane protein GQZ26_02535 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) GQZ26_02545 ENOG4105DPN Oligoendopeptidase f GQZ26_02555 ENOG4108Z18 K06886 hemoglobin GQZ26_02560 ENOG4105MIX Adenylate cyclase GQZ26_02565 ENOG4106EFP UPF0738 protein GQZ26_02580 ENOG4105EMS pseudouridine synthase GQZ26_02600 ENOG4105K64 Glycosyl transferase, family 2 GQZ26_02620 ENOG4107TVC Glycosyl transferase, family 2 GQZ26_02640 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) GQZ26_02645 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase GQZ26_02655 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase GQZ26_02730 ENOG4105CK7 Sodium proline symporter GQZ26_02735 ENOG4105CRQ synthase (Component I) GQZ26_02740 ENOG4105DDQ anthranilate synthase GQZ26_02855 ENOG4105C7S Dehydrogenase GQZ26_02865 ENOG4105VZ8 Transcriptional regulator GQZ26_02885 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_02940 ENOG4105W5Q DNA repair protein (RadC GQZ26_02960 ENOG4105VTR Integrase GQZ26_02965 ENOG4105CVR type I restriction-modification system GQZ26_02980 ENOG4105DZR Type I site-specific deoxyribonuclease GQZ26_03005 ENOG4105DZ1 carboxypeptidase GQZ26_03045 ENOG4105C26 Dehydrogenase GQZ26_03055 ENOG4105F38 ABC transporter, permease GQZ26_03060 ENOG4105D38 putrescine abc transporter GQZ26_03065 ENOG4107RUE extracellular solute-binding protein family 1 GQZ26_03075 ENOG4105EYF MMPL domain protein GQZ26_03085 ENOG4108YBP pseudouridine synthase GQZ26_03095 ENOG4105K4I Scp-like extracellular GQZ26_03100 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) GQZ26_03105 ENOG4105CQB FAD linked oxidase domain protein GQZ26_03120 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GQZ26_03125 ENOG4105BZU Histidine kinase GQZ26_03130 ENOG4105JXH GntR family transcriptional regulator GQZ26_03160 ENOG4108QTI )-transporter GQZ26_03165 ENOG4107TS3 membrane protein, TerC GQZ26_03170 ENOG4105CZN Potassium uptake protein GQZ26_03175 ENOG410681C small acid-soluble spore protein GQZ26_03180 ENOG4108Z7G MaoC domain protein dehydratase GQZ26_03200 ENOG4105CHR reductase GQZ26_03230 ENOG4105C4Y ABC transporter GQZ26_03260 ENOG4105E98 transcriptional regulator DeoR family GQZ26_03270 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) GQZ26_03280 ENOG4105PXI polysaccharide deacetylase GQZ26_03290 ENOG4105BZU Histidine kinase GQZ26_03295 ENOG41090MY MarR family Transcriptional regulator GQZ26_03305 ENOG4106DF1 GQZ26_03310 ENOG4105BZU Histidine kinase GQZ26_03320 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase GQZ26_03325 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) GQZ26_03365 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) GQZ26_03385 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GQZ26_03390 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family GQZ26_03395 ENOG4105CZV ABC transporter GQZ26_03405 ENOG4105CJ1 ABC, transporter GQZ26_03445 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A GQZ26_03450 ENOG4105EA8 2-Nitropropane dioxygenase GQZ26_03455 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD GQZ26_03465 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein GQZ26_03485 ENOG4105NQC Flavodoxin GQZ26_03510 ENOG4107QMU Mate efflux family protein GQZ26_03545 ENOG4105CZN Potassium uptake protein GQZ26_03550 ENOG41063Y9 GQZ26_03555 ENOG4105KBJ sporulation protein ytfj GQZ26_03575 ENOG4105CM2 brancheD-chain amino acid aminotransferase GQZ26_03580 ENOG4105C7K acetolactate synthase GQZ26_03585 ENOG4108ZP8 Acetolactate synthase small subunit GQZ26_03660 ENOG4107RVV histidinol phosphate phosphatase, hisj family GQZ26_03675 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase GQZ26_03680 ENOG4105E0M Sulfatase GQZ26_03690 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) GQZ26_03710 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) GQZ26_03715 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) GQZ26_03730 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein GQZ26_03735 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein GQZ26_03740 ENOG4105C8J )-transporter GQZ26_03765 ENOG4105DFD Na H antiporter GQZ26_03790 ENOG4105WH1 Two component transcriptional regulator luxr family GQZ26_03855 ENOG4105CJ3 phosphate transporter GQZ26_03860 ENOG4107GRR phosphate transport regulator GQZ26_03865 ENOG4105BZ4 penicillin-binding protein GQZ26_03885 ENOG4105I3N Conserved Protein GQZ26_03900 ENOG4105BZU Histidine kinase GQZ26_03930 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GQZ26_03935 ENOG4105DZ1 carboxypeptidase GQZ26_03940 ENOG4108JIC nucleoside recognition domain protein GQZ26_03950 ENOG4105FE9 pseudouridine synthase GQZ26_03960 ENOG4107TWT Cytochrome c biogenesis protein GQZ26_03965 ENOG4105CRE cytochrome C GQZ26_03970 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GQZ26_03975 ENOG4105BZU Histidine kinase GQZ26_03980 ENOG4108WBT adenosyltransferase GQZ26_03985 ENOG41063SB peptidase GQZ26_03995 ENOG4108SAX Membrane GQZ26_04010 ENOG4105C9U ATP-dependent DNA helicase RecQ GQZ26_04015 ENOG4105I7S Abortive infection protein GQZ26_04025 ENOG4107RGJ metallophosphoesterase GQZ26_04030 ENOG4107X2D transcriptional regulator, merr family GQZ26_04035 ENOG4108S6Z Negative regulator of genetic competence GQZ26_04060 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase GQZ26_04065 ENOG4105HDK L-asparaginase GQZ26_04095 ENOG4105S2F GQZ26_04100 ENOG41065D1 GQZ26_04130 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) GQZ26_04145 ENOG4105XXQ heptaprenyl diphosphate synthase component I GQZ26_04155 ENOG4105EAH synthase GQZ26_04175 ENOG4105CIH Imidazole acetol-phosphate transaminase GQZ26_04180 ENOG41068YB TPR repeat-containing protein GQZ26_04195 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) GQZ26_04200 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) GQZ26_04240 ENOG4108JYZ YitT family GQZ26_04245 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase GQZ26_04260 ENOG4105FJR Lmbe family GQZ26_04265 ENOG4105CPK Glycosyl transferase (Group 1 GQZ26_04300 ENOG4105DVT helicase GQZ26_04305 ENOG4105YAC GQZ26_04325 ENOG4105CSM endonuclease III GQZ26_04390 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) GQZ26_04400 ENOG4105DVT helicase GQZ26_04405 ENOG4105CTD carboxy-peptidase GQZ26_04415 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) GQZ26_04430 ENOG4105C2W permease GQZ26_04435 ENOG4105DHF Membrane GQZ26_04440 ENOG410890F Dynamin family GQZ26_04450 ENOG4108W0I acetyltransferase GQZ26_04460 ENOG4105KHC sulfurtransferase GQZ26_04540 ENOG41081VK Ribonuclease GQZ26_04605 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) GQZ26_04615 ENOG4107RWR Sodium hydrogen exchanger GQZ26_04620 ENOG4105CN5 Metallo-Beta-Lactamase GQZ26_04625 ENOG4108Z5V transcriptional regulator, merr family GQZ26_04640 ENOG4105H67 Protein of unknown function (DUF421) GQZ26_04645 ENOG41080C8 DUF218 domain GQZ26_04680 ENOG4107Y80 Major Facilitator superfamily GQZ26_04710 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) GQZ26_04720 ENOG4107R0U MotA TolQ exbB proton channel GQZ26_04725 ENOG4105ER2 Ompa motb domain protein GQZ26_04730 ENOG4107YTP response regulator receiver protein GQZ26_04735 ENOG4105CBS Chea signal transduction histidine kinase GQZ26_04740 ENOG4105DD5 Flagellar motor switch protein GQZ26_04755 ENOG4105BZU Histidine kinase GQZ26_04775 ENOG4105E1Q flagellar hook-associated protein GQZ26_04780 ENOG4105DTJ flagellar hook-associated protein GQZ26_04785 ENOG4107TPX flagellar hook-associated GQZ26_04800 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) GQZ26_04805 ENOG4108ZC9 flagellar basal-body rod protein flgc GQZ26_04810 ENOG41075Z6 flagellar hook-basal body complex protein fliE GQZ26_04815 ENOG4107U2N Flagellar M-ring protein GQZ26_04820 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) GQZ26_04855 ENOG4105BZE flagellar hook protein, FlgE GQZ26_04870 ENOG4107R88 Chemotaxis protein (CheV) GQZ26_04880 ENOG4105I03 Flagellin GQZ26_04885 ENOG4105I03 Flagellin GQZ26_04890 ENOG4105E4C Lytic transglycosylase catalytic GQZ26_04900 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) GQZ26_04905 ENOG4105DD5 Flagellar motor switch protein GQZ26_04915 ENOG4105CN7 Flagellar biosynthetic protein FliP GQZ26_04920 ENOG4105VS8 Flagellar biosynthetic protein fliq GQZ26_04930 ENOG4105D00 flagellar biosynthetic protein flhB GQZ26_04935 ENOG4105D7B Flagellar biosynthesis protein flha GQZ26_04940 ENOG4105FZW flagellar biosynthesis regulator FlhF GQZ26_04945 ENOG4105KTQ flagellar basal-body rod protein GQZ26_04950 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) GQZ26_04985 ENOG4105KAC Antibiotic biosynthesis monooxygenase GQZ26_05005 ENOG4108U4N (sortase) family GQZ26_05030 ENOG4105DUM transcriptional regulator, lysR family GQZ26_05035 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GQZ26_05070 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr GQZ26_05095 ENOG4105CVJ phosphoglycerate mutase GQZ26_05115 ENOG4105K56 Transcriptional regulator GQZ26_05125 ENOG4105CAQ asparagine synthetase GQZ26_05145 ENOG4105PGM cation diffusion facilitator family transporter GQZ26_05155 ENOG4105DRR Transcriptional regulator, GntR family GQZ26_05170 ENOG4105DFD Na H antiporter GQZ26_05175 ENOG4105C9Q fumarate hydratase class II GQZ26_05195 ENOG4107QJQ Mate efflux family protein GQZ26_05200 ENOG4105EC3 peptidase S51, dipeptidase E GQZ26_05240 ENOG4106BRA Membrane GQZ26_05275 ENOG4105CJ1 ABC, transporter GQZ26_05295 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) GQZ26_05305 ENOG4108IJ0 Aspartate ammonia-lyase GQZ26_05310 ENOG4105C6K Malic enzyme GQZ26_05370 ENOG4105FVX GQZ26_05415 ENOG4105CSR polyphosphate kinase 2 GQZ26_05420 ENOG4105U3E Transcriptional regulator GQZ26_05430 ENOG4105DXI Major Facilitator superfamily GQZ26_05445 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) GQZ26_05455 ENOG4105EU0 Major facilitator Superfamily GQZ26_05460 ENOG4105C6T cysteine synthase GQZ26_05480 ENOG4105C8J )-transporter GQZ26_05490 ENOG4105X5K response regulator receiver protein GQZ26_05495 ENOG4105H67 Protein of unknown function (DUF421) GQZ26_05510 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) GQZ26_05515 ENOG4105CM2 brancheD-chain amino acid aminotransferase GQZ26_05520 ENOG4105C7K acetolactate synthase GQZ26_05525 ENOG4108ZP8 Acetolactate synthase small subunit GQZ26_05530 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase GQZ26_05540 ENOG4105C7B Threonine dehydratase GQZ26_05565 ENOG4105C6X Major Facilitator GQZ26_05570 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b GQZ26_05580 ENOG4105DY9 regulatoR GQZ26_05585 ENOG4105CYC Transferase GQZ26_05605 ENOG4105F6J Alpha beta hydrolase fold GQZ26_05615 ENOG41068WN GQZ26_05620 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GQZ26_05635 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) GQZ26_05650 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) GQZ26_05655 ENOG4105C0X amino acid GQZ26_05685 ENOG4107RHR regulatoR GQZ26_05695 ENOG4105D9N nucleoside GQZ26_05700 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) GQZ26_05720 ENOG4107RAQ aminopeptidase GQZ26_05765 ENOG4108T5E Copper resistance protein GQZ26_05770 ENOG4105KTB nuclear export factor GLE1 GQZ26_05775 ENOG4107RT3 EamA-like transporter family GQZ26_05780 ENOG4105GZI Transcriptional regulator GQZ26_05785 ENOG4108Z40 Transcriptional regulator GQZ26_05790 ENOG4107ZXU DSBA oxidoreductase GQZ26_05795 ENOG4108TVJ Nitroreductase GQZ26_05805 ENOG4106F5Q Membrane GQZ26_05810 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) GQZ26_05820 ENOG4105CKI cobalamin synthesis protein GQZ26_05830 ENOG4105C0Z ABC transporter GQZ26_05835 ENOG4108IV0 ABC, transporter GQZ26_05840 ENOG4105C32 Amino acid ABC transporter (Permease) GQZ26_05850 ENOG4105SKE transcriptional Regulator LysR family GQZ26_05860 ENOG4105MDS 4-oxalocrotonate tautomerase GQZ26_05880 ENOG4105C4M (Ubiquinol oxidase) subunit I GQZ26_05885 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GQZ26_05890 ENOG4108JJ9 ABC, transporter GQZ26_05895 ENOG4108JJ8 (ABC) transporter GQZ26_05915 ENOG4108UT6 Transferase hexapeptide repeat containing protein GQZ26_05940 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A GQZ26_05970 ENOG4105BZ1 (ABC) transporter GQZ26_05975 ENOG4105EFI regulatoR GQZ26_06000 ENOG41075D4 Aminoglycoside 6-adenylyltransferase GQZ26_06005 ENOG4108ZJ4 polysaccharide deacetylase GQZ26_06025 ENOG4105D6E homoserine dehydrogenase GQZ26_06050 ENOG4108KGH TRANSCRIPTIONal GQZ26_06055 ENOG4105BZU Histidine kinase GQZ26_06060 ENOG4107VMI polysaccharide deacetylase GQZ26_06070 ENOG4105KT7 mgtC SapB transporter GQZ26_06075 ENOG4105VRR gCN5-related N-acetyltransferase GQZ26_06080 ENOG4105YWU small acid-soluble spore protein GQZ26_06090 ENOG4108ZUB Lysine exporter protein (Lyse ygga) GQZ26_06095 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family GQZ26_06135 ENOG4108FPN Integrase GQZ26_06140 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GQZ26_06145 ENOG4105ZX1 Transposase C GQZ26_06160 ENOG4105KRN Transcriptional regulator, abrb family GQZ26_06180 ENOG4108KB1 transcriptional regulator, arac family GQZ26_06190 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component GQZ26_06195 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component GQZ26_06205 ENOG4105DKQ ROK family GQZ26_06210 ENOG4105E70 isomerase GQZ26_06215 ENOG4105CE4 GlcNAc 6-P deacetylase GQZ26_06220 ENOG4105DE4 1-phosphofructokinase GQZ26_06225 ENOG4105D2M Aldolase GQZ26_06230 ENOG4105ESP cell wall surface anchor family protein GQZ26_06240 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase GQZ26_06245 ENOG4105YVS arsR family transcriptional regulator GQZ26_06250 ENOG4105CPC Aldo Keto reductase GQZ26_06255 ENOG4107XZQ multidrug resistance protein GQZ26_06280 ENOG4105C8Q Methyl-accepting chemotaxis GQZ26_06295 ENOG4108K88 Membrane GQZ26_06300 ENOG4108WPJ Ferritin-like domain GQZ26_06315 ENOG4105DEN Luciferase family GQZ26_06330 ENOG4105VMI -acetyltransferase GQZ26_06335 ENOG4107QM2 Aldo Keto reductase GQZ26_06340 ENOG4105CKI cobalamin synthesis protein GQZ26_06350 ENOG4105DSE periplasmic solute binding protein GQZ26_06355 ENOG4105K4T epimerase GQZ26_06365 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) GQZ26_06390 ENOG4105CVJ phosphoglycerate mutase GQZ26_06410 ENOG4107T5V SNARE associated Golgi GQZ26_06435 ENOG4108S4H thioesterase Superfamily protein GQZ26_06445 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) GQZ26_06465 ENOG4105SXS Protein of unknown function (DUF456) GQZ26_06470 ENOG4105C37 (CBS) domain GQZ26_06490 ENOG4108Z7R Chaperone CsaA GQZ26_06510 ENOG4108ZRV stage ii sporulation protein p GQZ26_06520 ENOG4108VXD carboxy-peptidase GQZ26_06530 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) GQZ26_06555 ENOG4108X4Q Hydrolase GQZ26_06565 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) GQZ26_06570 ENOG4107RBS Methyltransferase GQZ26_06585 ENOG41087PP glycosyltransferase MGT family GQZ26_06590 ENOG4108JYZ YitT family GQZ26_06595 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family GQZ26_06625 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) GQZ26_06650 ENOG4105KBJ sporulation protein ytfj GQZ26_06675 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) GQZ26_06695 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GQZ26_06710 ENOG41067QW Transcriptional regulator GQZ26_06740 ENOG4105KRN Transcriptional regulator, abrb family GQZ26_06815 ENOG410682Q Phage transcriptional regulator, ArpU GQZ26_06850 ENOG4105CAR Terminase, large subunit GQZ26_06860 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) GQZ26_07000 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein GQZ26_07005 ENOG4105EMN RNA polymerase sigma factor GQZ26_07020 ENOG4105CNW domain protein GQZ26_07030 ENOG4108V06 Glutathione peroxidase GQZ26_07045 ENOG4105C7R Atpase associated with various cellular activities aaa_3 GQZ26_07055 ENOG4108IUE nitrate reductase beta subunit GQZ26_07060 ENOG4105R3A Nitrate reductase GQZ26_07070 ENOG4107V6Q Cyclic nucleotide-binding domain GQZ26_07075 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) GQZ26_07080 ENOG4105D06 uba thif-type nad fad binding protein GQZ26_07085 ENOG4105CVM Molybdenum cofactor synthesis domain protein GQZ26_07090 ENOG4108ZAF Molybdopterin GQZ26_07120 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein GQZ26_07125 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein GQZ26_07130 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) GQZ26_07135 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit GQZ26_07140 ENOG4108IFG nitrite reductase, (NAD(P)H) GQZ26_07145 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) GQZ26_07180 ENOG4105MCT stage V sporulation protein S GQZ26_07205 ENOG4105C5H ABC transporter GQZ26_07220 ENOG4108UUM single-stranded DNA-binding protein GQZ26_07250 ENOG4107YX5 Pfam:DUF548 GQZ26_07300 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) GQZ26_07305 ENOG4105C5S asparaginyl-tRNA synthetase GQZ26_07310 ENOG4105C8J )-transporter GQZ26_07330 ENOG4107XGZ Hydrolase GQZ26_07335 ENOG4105CY2 Citrate transporter GQZ26_07340 ENOG4105C0A alcohol dehydrogenase GQZ26_07355 ENOG4105KD7 acetyltransferase GQZ26_07360 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase GQZ26_07385 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 GQZ26_07400 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) GQZ26_07420 ENOG4107RVG penicillin-binding protein GQZ26_07425 ENOG4107XM6 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) GQZ26_07430 ENOG4105E9Q Acyl-transferase GQZ26_07435 ENOG4108UT2 hemolysin iii GQZ26_07445 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) GQZ26_07455 ENOG4108RCR degv family GQZ26_07460 ENOG4105E8R UPF0173 metal-dependent hydrolase GQZ26_07465 ENOG4108KF3 Electron transport protein SCO1 SenC GQZ26_07470 ENOG4107Y70 Heat shock protein GQZ26_07475 ENOG4105CAQ asparagine synthetase GQZ26_07495 ENOG4108MES Periplasmic binding protein GQZ26_07500 ENOG4105F0I Aminotransferase GQZ26_07530 ENOG4105D8X mechanosensitive ion channel GQZ26_07535 ENOG4105BZU Histidine kinase GQZ26_07540 ENOG4105WH1 Two component transcriptional regulator luxr family GQZ26_07550 ENOG4106KNT transcriptional regulator GQZ26_07610 ENOG4108IJ8 ABC transporter GQZ26_07615 ENOG4105E90 ABC transporter GQZ26_07650 ENOG4105C37 (CBS) domain GQZ26_07675 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) GQZ26_07690 ENOG4107S4Y M20 DapE family protein YgeY GQZ26_07695 ENOG4108TSC N-acetyltransferase GQZ26_07700 ENOG4108JUB Transcriptional regulator GQZ26_07705 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein GQZ26_07745 ENOG4108N23 SpoOM-related protein GQZ26_07750 ENOG410841Q phosphoesterase PA-phosphatase related protein GQZ26_07760 ENOG4105SZ6 Thioredoxin GQZ26_07770 ENOG4108TFU terminase (Small subunit) GQZ26_07800 ENOG4108AEY RNA polymerase sigma factor GQZ26_07830 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) GQZ26_07875 ENOG4105BZ4 penicillin-binding protein GQZ26_07885 ENOG4105CZM Major Facilitator GQZ26_07890 ENOG4105W8X HesB YadR YfhF-family protein GQZ26_07900 ENOG4105DXD 2-methylcitrate dehydratase GQZ26_07905 ENOG4105CR4 methylisocitrate lyase GQZ26_07910 ENOG4105C1G acyl-Coa dehydrogenase GQZ26_07915 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GQZ26_07925 ENOG4105N14 lysine exporter protein LysE YggA GQZ26_07930 ENOG4105E39 Enoyl-CoA hydratase GQZ26_07945 ENOG4107RFY SbcCD D subunit GQZ26_07975 ENOG4105FCD Major Facilitator GQZ26_07980 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase GQZ26_07985 ENOG4105E4F Isochorismate synthase GQZ26_07990 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase GQZ26_08010 ENOG4105C0R drug resistance transporter emrb qaca subfamily GQZ26_08025 ENOG4105K70 DNA-binding protein GQZ26_08045 ENOG4105BZG amino acid carrier protein GQZ26_08075 ENOG4105FE9 pseudouridine synthase GQZ26_08080 ENOG4105C22 threonyL-tRNA synthetase GQZ26_08085 ENOG4105C19 ABC transporter GQZ26_08120 ENOG4108D32 Methyltransferase GQZ26_08130 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_08155 ENOG41081I9 integral membrane protein GQZ26_08180 ENOG4105EYF MMPL domain protein GQZ26_08200 ENOG4105WCN acetyltransferase GQZ26_08225 ENOG4105C1Q protoporphyrinogen oxidase GQZ26_08235 ENOG41068WN GQZ26_08245 ENOG4105VEQ Cold shock protein GQZ26_08265 ENOG410667J hydrolase GQZ26_08285 ENOG4107V2S Transcriptional regulator GQZ26_08290 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) GQZ26_08305 ENOG4105DND Transcriptional regulator GQZ26_08310 ENOG4108RPX mosc domain containing protein GQZ26_08325 ENOG4105BZ1 (ABC) transporter GQZ26_08330 ENOG4105BZ1 (ABC) transporter GQZ26_08345 ENOG4108JCI Transcriptional regulator GQZ26_08385 ENOG4108KPJ rna polymerase sigma factor GQZ26_08405 ENOG4105F32 YngK protein GQZ26_08430 ENOG4105RD7 BadF BadG BcrA BcrD GQZ26_08440 ENOG4107STF Involved in phosphonate degradation (By similarity) GQZ26_08460 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) GQZ26_08470 ENOG4105C1J atp-dependent rna helicase GQZ26_08490 ENOG4108RZE Tetr family transcriptional regulator GQZ26_08510 ENOG41088CC tellurite resistance protein tehB GQZ26_08520 ENOG4107RA9 decarboxylase GQZ26_08545 ENOG4105CIN aminoacyl-histidine dipeptidase GQZ26_08570 ENOG4107RF6 penicillin-binding protein GQZ26_08575 ENOG4107RF6 penicillin-binding protein GQZ26_08585 ENOG4105DIN metallophosphoesterase GQZ26_08595 ENOG4105CJ1 ABC, transporter GQZ26_08605 ENOG4107Z3H Transcriptional regulator, TetR family GQZ26_08620 ENOG4105C1G acyl-Coa dehydrogenase GQZ26_08625 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase GQZ26_08630 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit GQZ26_08635 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase GQZ26_08640 ENOG4105E39 Enoyl-CoA hydratase GQZ26_08645 ENOG4107QX3 carboxylase GQZ26_08650 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) GQZ26_08665 ENOG4105DBI uridine monophosphokinase GQZ26_08690 ENOG4105T9C HD domain GQZ26_08700 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) GQZ26_08745 ENOG4105FQP Beta-lactamase GQZ26_08755 ENOG4107Y80 Major Facilitator superfamily GQZ26_08765 ENOG41089UC methyltransferase, type 11 GQZ26_08810 ENOG4105CPQ Dehydrogenase GQZ26_08815 ENOG410900G Protein of unknown function (DUF421) GQZ26_08820 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) GQZ26_08835 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein GQZ26_08845 ENOG4105DK7 lysyl-tRNA synthetase GQZ26_08905 ENOG4105D6E homoserine dehydrogenase GQZ26_08920 ENOG4105ETU transcriptional activator (TenA GQZ26_09000 ENOG4107EV6 Inherit from COG: YD repeat protein GQZ26_09075 ENOG410667J hydrolase GQZ26_09085 ENOG4105BZU Histidine kinase GQZ26_09090 ENOG4107RF6 penicillin-binding protein GQZ26_09125 ENOG4108HGU Histidine kinase GQZ26_09135 ENOG4105RHY Pfam:UPF0157 GQZ26_09145 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase GQZ26_09150 ENOG4105CJN penicillin-binding protein GQZ26_09155 ENOG4108IG5 Transcriptional regulator GQZ26_09160 ENOG4105CHR reductase GQZ26_09220 ENOG4107VXM glycerophosphoryl diester phosphodiesterase GQZ26_09245 ENOG4107Y9U Membrane GQZ26_09255 ENOG4105EGD dinuclear metal center protein, YbgI family GQZ26_09275 ENOG4105FCD Major Facilitator GQZ26_09290 ENOG4105E09 nadh pyrophosphatase GQZ26_09295 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) GQZ26_09330 ENOG4108XI2 Domain of unknown function (DUF1963) GQZ26_09350 ENOG4108NRW Phospholipase, patatin family GQZ26_09355 ENOG4105KWG Pfam:DUF1696 GQZ26_09390 ENOG4105PKS Excinuclease abc c subunit domain protein GQZ26_09450 ENOG4105U0R haloacid dehalogenase-like hydrolase GQZ26_09470 ENOG4108IUM Glycogen debranching enzyme GQZ26_09485 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) GQZ26_09545 ENOG4105MSI germination protein ypeb GQZ26_09585 ENOG4107Z3H Transcriptional regulator, TetR family GQZ26_09630 ENOG4105E98 transcriptional regulator DeoR family GQZ26_09650 ENOG4107QKR Dehydrogenase GQZ26_09660 ENOG4107RUY (E1 component), alpha subunit GQZ26_09670 ENOG4105E1F short-chain dehydrogenase reductase GQZ26_09675 ENOG4105RHY Pfam:UPF0157 GQZ26_09680 ENOG4105DBI uridine monophosphokinase GQZ26_09715 ENOG4107SQ8 Glycine betaine GQZ26_09720 ENOG4108IJ7 Glycine betaine GQZ26_09745 ENOG4105E66 phosphoriboisomerase A GQZ26_09750 ENOG41082BV acetyltransferase GQZ26_09755 ENOG4108M1A Chitin-binding protein GQZ26_09760 ENOG41087PP glycosyltransferase MGT family GQZ26_09780 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) GQZ26_09785 ENOG4105MSB protein, conserved in bacteria GQZ26_09795 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 GQZ26_09815 ENOG4108Z7F N-acetyltransferase GQZ26_09835 ENOG4105EEM helicase GQZ26_09855 ENOG4105C9U ATP-dependent DNA helicase RecQ GQZ26_09905 ENOG4108M1A Chitin-binding protein GQZ26_09930 ENOG4105BZG amino acid carrier protein GQZ26_09935 ENOG4105C26 Dehydrogenase GQZ26_09940 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) GQZ26_09945 ENOG4105CTU Proline racemase GQZ26_09950 ENOG4105CTU Proline racemase GQZ26_09955 ENOG41080HI glycine oxidase GQZ26_09965 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein GQZ26_09995 ENOG4107T5V SNARE associated Golgi GQZ26_10000 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD GQZ26_10020 ENOG4105DTQ mandelate racemase muconate lactonizing GQZ26_10065 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) GQZ26_10070 ENOG4105BZU Histidine kinase GQZ26_10075 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GQZ26_10095 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 GQZ26_10120 ENOG4105EPR degv family GQZ26_10180 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) GQZ26_10185 ENOG4106K7D Major facilitator family transporter GQZ26_10210 ENOG4107BMA Transglycosylase associated protein GQZ26_10225 ENOG41089UC methyltransferase, type 11 GQZ26_10255 ENOG4105CHM Aminotransferase GQZ26_10270 ENOG4108ZMI UPF0477 protein GQZ26_10325 ENOG4105C02 permease GQZ26_10335 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) GQZ26_10340 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component GQZ26_10390 ENOG4108AQF aminoglycoside N(3)-acetyltransferase GQZ26_10435 ENOG4107VC0 DNA alkylation repair enzyme GQZ26_10445 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase GQZ26_10455 ENOG4107VMI polysaccharide deacetylase GQZ26_10460 ENOG4108ZCF integral membrane protein GQZ26_10465 ENOG4105E0M Sulfatase GQZ26_10470 ENOG4105C5H ABC transporter GQZ26_10480 ENOG4105EYF MMPL domain protein GQZ26_10485 ENOG41082JN Transcriptional regulator GQZ26_10505 ENOG4105CIH Imidazole acetol-phosphate transaminase GQZ26_10515 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase GQZ26_10540 ENOG41069ER domain protein GQZ26_10555 ENOG4105D4B ABC, transporter GQZ26_10565 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane GQZ26_10575 ENOG4105DKT Transcriptional regulator GQZ26_10580 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) GQZ26_10590 ENOG41061GT Aldolase GQZ26_10600 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) GQZ26_10630 ENOG4105II7 pyrroline-5-carboxylate reductase GQZ26_10640 ENOG4107258 Transcriptional regulator GQZ26_10650 ENOG4105E0Y RtcB Protein GQZ26_10655 ENOG4105ECK Fatty Acid Desaturase GQZ26_10665 ENOG4105G6Z alkaline phosphatase GQZ26_10675 ENOG4105VMP Transcriptional regulator GQZ26_10690 ENOG41090T1 Membrane GQZ26_10700 ENOG4108WCX response regulator GQZ26_10710 ENOG4105KNA -acetyltransferase GQZ26_10735 ENOG4105C7R Atpase associated with various cellular activities aaa_3 GQZ26_10755 ENOG4105C8Y Acetylornithine aminotransferase GQZ26_10765 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component GQZ26_10785 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes GQZ26_10815 ENOG4105C7R Atpase associated with various cellular activities aaa_3 GQZ26_10825 ENOG4108TVJ Nitroreductase GQZ26_10830 ENOG4105FS7 Transcriptional regulator GQZ26_10865 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family GQZ26_10875 ENOG4105C19 ABC transporter GQZ26_10900 ENOG4108DMH HTH_ARAC GQZ26_10905 ENOG4108XET gCN5-related N-acetyltransferase GQZ26_10965 ENOG410635A Membrane GQZ26_10970 ENOG4105KNA -acetyltransferase GQZ26_10975 ENOG4108IQI permease GQZ26_10985 ENOG4105F1N DNA alkylation repair GQZ26_11025 ENOG4107RF6 penicillin-binding protein GQZ26_11065 ENOG4105P4J Allophanate hydrolase, subunit 1 GQZ26_11070 ENOG4107258 Transcriptional regulator GQZ26_11080 ENOG4106N3A copper homeostasis protein cutc GQZ26_11085 ENOG4108ZRV stage ii sporulation protein p GQZ26_11090 ENOG4108ZHR arsR family transcriptional regulator GQZ26_11100 ENOG4105C0R drug resistance transporter emrb qaca subfamily GQZ26_11105 ENOG4105FDT acyl-CoA dehydrogenase GQZ26_11120 ENOG4105DWD nucleoside recognition domain protein GQZ26_11160 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) GQZ26_11235 ENOG4108IJ0 Aspartate ammonia-lyase GQZ26_11240 ENOG4105HDK L-asparaginase GQZ26_11245 ENOG4108IMY Transcriptional regulator GQZ26_11250 ENOG4105DQ6 Transposase GQZ26_11255 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) GQZ26_11260 ENOG4105CUB amino acid GQZ26_11270 ENOG4108NHD germination protein GQZ26_11275 ENOG4108Q8B Spore germination protein GQZ26_11295 ENOG4105CSV Glutaminase GQZ26_11325 ENOG4107QJQ Mate efflux family protein GQZ26_11335 ENOG4107QTZ amino acid GQZ26_11345 ENOG4105CH6 catalase GQZ26_11395 ENOG4108606 TspO/MBR family GQZ26_11400 ENOG4105CVP deoxyribo-dipyrimidine photolyase GQZ26_11425 ENOG4108TWJ NADH dehydrogenase subunit 5 GQZ26_11430 ENOG4105GPN Uncharacterized conserved protein (DUF2294) GQZ26_11455 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase GQZ26_11495 ENOG4105DET Rhamnulokinase GQZ26_11500 ENOG4107W7X Aldolase GQZ26_11510 ENOG4105CNN ABC, transporter GQZ26_11525 ENOG4105ETE Transcriptional regulator (LacI family GQZ26_11535 ENOG4105D6J arsenicaL-resistance protein GQZ26_11540 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase GQZ26_11545 ENOG41085FC arsR family transcriptional regulator GQZ26_11555 ENOG4105NAE bifunctional deaminase-reductase domain protein GQZ26_11575 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) GQZ26_11610 ENOG4108IG5 Transcriptional regulator GQZ26_11615 ENOG4105F27 Major Facilitator GQZ26_11620 ENOG4105M4P Tetr family transcriptional regulator GQZ26_11625 ENOG4105CHR reductase GQZ26_11630 ENOG4108YXU transcriptional regulator AsnC family GQZ26_11660 ENOG4105N0V mono-oxygenase ydhR GQZ26_11675 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) GQZ26_11735 ENOG4105K6H D-cysteine desulfhydrase GQZ26_11760 ENOG4105W1Y Transcriptional regulator GQZ26_11765 ENOG4105JQZ Methyltransferase GQZ26_11785 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) GQZ26_11805 ENOG4105BZU Histidine kinase GQZ26_11820 ENOG4108U05 Transcriptional regulator GQZ26_11825 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 GQZ26_11835 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) GQZ26_11865 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A GQZ26_11880 ENOG4108JQ1 Dehydrogenase GQZ26_11900 ENOG41082W1 Cupin 2, conserved barrel domain protein GQZ26_11925 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase GQZ26_11965 ENOG4108ISG Major Facilitator GQZ26_11980 ENOG4107MII Sugar-specific transcriptional regulator TrmB GQZ26_11985 ENOG4105CZM Major Facilitator GQZ26_12000 ENOG4105DA5 (ABC) transporter GQZ26_12015 ENOG4105RXJ GQZ26_12020 ENOG4105KPY Small multidrug resistance protein GQZ26_12030 ENOG4107AUC GQZ26_12040 ENOG4105CRW Short chain fatty acid transporter GQZ26_12085 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) GQZ26_12125 ENOG4107TXC Transcriptional regulator GQZ26_12145 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_12150 ENOG4105RHY Pfam:UPF0157 GQZ26_12155 ENOG4108Z66 YbaK ebsC protein GQZ26_12175 ENOG4105KVH Transcriptional regulator GQZ26_12180 ENOG4108RCM Nitroreductase GQZ26_12200 ENOG4108PSK reductase GQZ26_12210 ENOG4105CJ1 ABC, transporter GQZ26_12260 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase GQZ26_12265 ENOG4105DKQ ROK family GQZ26_12270 ENOG4108UW5 maltose o-acetyltransferase GQZ26_12275 ENOG4105C31 Tryptophanyl-tRNA synthetase GQZ26_12310 ENOG4105DMQ Methyltransferase GQZ26_12320 ENOG4105EV4 Multidrug resistance protein mdtH GQZ26_12345 ENOG4105C37 (CBS) domain GQZ26_12395 ENOG4105DDN Pentapeptide repeat-containing protein GQZ26_12400 ENOG4105XDF Protein of unknown function (DUF1272) GQZ26_12405 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) GQZ26_12410 ENOG4105CMG Carbohydrate kinase GQZ26_12415 ENOG4105C6Z Gluconate GQZ26_12420 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GQZ26_12435 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase GQZ26_12440 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase GQZ26_12445 ENOG4105CIS alcohol dehydrogenase GQZ26_12450 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone GQZ26_12465 ENOG4105EWI Short-chain dehydrogenase reductase Sdr GQZ26_12480 ENOG4105CV8 reductase GQZ26_12485 ENOG4105F27 Major Facilitator GQZ26_12500 ENOG4105C44 Serine transporter GQZ26_12505 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_12535 ENOG4105KVH Transcriptional regulator GQZ26_12540 ENOG4108TZY GntR Family Transcriptional Regulator GQZ26_12545 ENOG4105D9R oxidoreductase GQZ26_12550 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase GQZ26_12555 ENOG4105KVH Transcriptional regulator GQZ26_12560 ENOG4105KVH Transcriptional regulator GQZ26_12600 ENOG4105JAB phenazine biosynthesis protein, phzf family GQZ26_12610 ENOG4105CHR reductase GQZ26_12625 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein GQZ26_12630 ENOG4105KVH Transcriptional regulator GQZ26_12645 ENOG4108ZJ4 polysaccharide deacetylase GQZ26_12720 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) GQZ26_12760 ENOG4105H3G oxidoreductase GQZ26_12805 ENOG4105K7K Transcriptional regulator GQZ26_12810 ENOG4105CIS alcohol dehydrogenase GQZ26_12840 ENOG4108TN2 lmbE family GQZ26_12850 ENOG4107R3E Citrate transporter GQZ26_12865 ENOG4108MES Periplasmic binding protein GQZ26_12870 ENOG4105EHG Permease protein GQZ26_12875 ENOG4105DQ5 transport system permease protein GQZ26_12880 ENOG4105NX3 Membrane GQZ26_12900 ENOG4107CUJ Protein of unknown function (DUF2690) GQZ26_12910 ENOG4107V2S Transcriptional regulator GQZ26_12930 ENOG4105C98 muts2 protein GQZ26_12935 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase GQZ26_12970 ENOG4107VXM glycerophosphoryl diester phosphodiesterase GQZ26_12980 ENOG41082BM Transcriptional regulator, arsr family GQZ26_12985 ENOG4105CIS alcohol dehydrogenase GQZ26_12995 ENOG4107JM4 Tetratricopeptide repeat GQZ26_13010 ENOG4105RHY Pfam:UPF0157 GQZ26_13020 ENOG4105C09 Bile acid GQZ26_13025 ENOG4105CQB FAD linked oxidase domain protein GQZ26_13055 ENOG4105KT7 mgtC SapB transporter GQZ26_13070 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase GQZ26_13075 ENOG4105EAB amino acid AbC transporter GQZ26_13085 ENOG4108HW4 amino acid AbC transporter GQZ26_13090 ENOG41073R8 VanW family GQZ26_13100 ENOG4108R1P GQZ26_13115 ENOG4105VEQ Cold shock protein GQZ26_13135 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) GQZ26_13155 ENOG410904N short-chain dehydrogenase reductase GQZ26_13165 ENOG4106IQC argininosuccinate lyase GQZ26_13180 ENOG4108IA2 Sodium pantothenate symporter GQZ26_13190 ENOG4105C26 Dehydrogenase GQZ26_13195 ENOG4105CHR reductase GQZ26_13205 ENOG4105EWU Squalene--hopene cyclase GQZ26_13215 ENOG4105FR1 rard protein GQZ26_13220 ENOG410696E Membrane GQZ26_13235 ENOG4105D1F ATP-binding protein GQZ26_13245 ENOG4108ZAF Molybdopterin GQZ26_13250 ENOG4105CVM Molybdenum cofactor synthesis domain protein GQZ26_13255 ENOG4105D06 uba thif-type nad fad binding protein GQZ26_13260 ENOG4105TMB Formate nitrite transporter GQZ26_13270 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) GQZ26_13275 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) GQZ26_13285 ENOG4108JB9 formate dehydrogenase GQZ26_13290 ENOG4105E1K spore germination protein GQZ26_13350 ENOG4107QJT sodium dicarboxylate symporter GQZ26_13355 ENOG4108KGH TRANSCRIPTIONal GQZ26_13365 ENOG4105EMN RNA polymerase sigma factor GQZ26_13380 ENOG4105CIG ABC transporter GQZ26_13390 ENOG4105D9R oxidoreductase GQZ26_13400 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GQZ26_13405 ENOG4105K4P CoA-binding domain protein GQZ26_13410 ENOG4105C0H protease GQZ26_13415 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GQZ26_13425 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase GQZ26_13435 ENOG4105W8X HesB YadR YfhF-family protein GQZ26_13465 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) GQZ26_13470 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen GQZ26_13480 ENOG4105BZ1 (ABC) transporter GQZ26_13485 ENOG4108I0Z Aconitate hydratase GQZ26_13515 ENOG4105E5W Transporter GQZ26_13515 ENOG4105E5W Transporter GQZ26_13540 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) GQZ26_13570 ENOG4107F3J Amp-dependent synthetase and ligase GQZ26_13575 ENOG4107ZYJ bioY protein GQZ26_13580 ENOG4105CEY Amp-dependent synthetase and ligase GQZ26_13595 ENOG4108IMY Transcriptional regulator GQZ26_13640 ENOG4107AYK membrAne GQZ26_13650 ENOG4105BZU Histidine kinase GQZ26_13655 ENOG4105FBA Phospholipase Carboxylesterase GQZ26_13660 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase GQZ26_13665 ENOG4105CK7 Sodium proline symporter GQZ26_13675 ENOG4105CBC glutamate synthase GQZ26_13680 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GQZ26_13685 ENOG4108VJ1 Transcriptional regulator (CarD family GQZ26_13690 ENOG4108903 Formimidoylglutamase GQZ26_13715 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) GQZ26_13755 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_13770 ENOG4107QIV Cytochrome c biogenesis protein GQZ26_13780 ENOG4105CH2 amidohydrolase GQZ26_13790 ENOG4105CJ1 ABC, transporter GQZ26_13800 ENOG4107RSM transcriptional regulator GQZ26_13810 ENOG41067MG lrgb family GQZ26_13835 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase GQZ26_13850 ENOG4105BZ1 (ABC) transporter GQZ26_13875 ENOG4105T6C Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps GQZ26_13940 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GQZ26_13970 ENOG4105D5T phosphonate abc transporter GQZ26_13975 ENOG4108HW3 (ABC) transporter GQZ26_13980 ENOG4105CGH 5'-nucleotidase GQZ26_13990 ENOG4108SVB resolvase GQZ26_14010 ENOG4105K7K Transcriptional regulator GQZ26_14015 ENOG4105C5F glutamine synthetase GQZ26_14020 ENOG4105KV4 Transcriptional regulator GQZ26_14030 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) GQZ26_14040 ENOG4106F1P AAA ATPase, central domain protein GQZ26_14070 ENOG41069ER domain protein GQZ26_14080 ENOG4105DE4 1-phosphofructokinase GQZ26_14085 ENOG4105E98 transcriptional regulator DeoR family GQZ26_14090 ENOG4107QW4 alcohol dehydrogenase GQZ26_14095 ENOG4108SJC Membrane GQZ26_14105 ENOG4105C85 amino acid GQZ26_14120 ENOG4105TMB Formate nitrite transporter GQZ26_14125 ENOG4105K70 DNA-binding protein GQZ26_14135 ENOG4105C59 p-type ATPase GQZ26_14140 ENOG410681U heavy metal transport detoxification protein GQZ26_14145 ENOG4105VPX protein, conserved in bacteria GQZ26_14155 ENOG4105NIV Esterase GQZ26_14160 ENOG4105E0A ABC, transporter GQZ26_14190 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) GQZ26_14195 ENOG4105D03 DNA-3-methyladenine glycosylase II GQZ26_14215 ENOG4105BZU Histidine kinase GQZ26_14260 ENOG4105F0V Cell wall hydrolase GQZ26_14275 ENOG4105E0M Sulfatase GQZ26_14280 ENOG410890F Dynamin family GQZ26_14290 ENOG4107QHE Choloylglycine hydrolase GQZ26_14315 ENOG4105DA5 (ABC) transporter GQZ26_14350 ENOG4105DQU oxidoreductase, subunit beta GQZ26_14355 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein GQZ26_14360 ENOG4108IGT Dipeptidase GQZ26_14365 ENOG4105MCT stage V sporulation protein S GQZ26_14370 ENOG4105D48 metallophosphoesterase GQZ26_14375 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) GQZ26_14395 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase GQZ26_14410 ENOG4105XZV Protein of unknown function (DUF3243) GQZ26_14415 ENOG4108RKS Short-chain dehydrogenase reductase Sdr GQZ26_14435 ENOG4105UIB (ABC) transporter GQZ26_14440 ENOG4108JQ9 ABC transporter GQZ26_14445 ENOG4105DIH basic membrane GQZ26_14450 ENOG4105FDP GntR family transcriptional regulator GQZ26_14465 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit GQZ26_14475 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) GQZ26_14485 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) GQZ26_14490 ENOG4108S0H Dipicolinic acid synthetase, b subunit GQZ26_14495 ENOG4105E35 Dipicolinate synthase subunit A GQZ26_14505 ENOG4105C1V Peptidase, M16 GQZ26_14525 ENOG4105DTN riboflavin biosynthesis protein ribF GQZ26_14540 ENOG4105W7A Protein of unknown function (DUF503) GQZ26_14550 ENOG4105VHM ribosomal protein GQZ26_14555 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination GQZ26_14560 ENOG4105CHV Transcription elongation factor NusA GQZ26_14570 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) GQZ26_14580 ENOG4105DZP Membrane-associated zinc metalloprotease GQZ26_14590 ENOG4105KNE Phosphatidate cytidylyltransferase GQZ26_14635 ENOG4108HE4 integrase family GQZ26_14645 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) GQZ26_14650 ENOG4105C79 DNA protecting protein DprA GQZ26_14655 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha GQZ26_14670 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) GQZ26_14695 ENOG4105VB6 UPF0109 protein GQZ26_14715 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) GQZ26_14720 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) GQZ26_14735 ENOG4105CHR reductase GQZ26_14740 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase GQZ26_14755 ENOG4105CB5 ATP-dependent DNA helicase recG GQZ26_14760 ENOG4105DP4 dak2 domain fusion protein ylov GQZ26_14765 ENOG4108ZAA Alkaline-shock protein GQZ26_14780 ENOG4105FJ0 thiamine GQZ26_14785 ENOG4105DJV ribulose-phosphate 3-epimerase GQZ26_14795 ENOG4105D9P serine threonine protein kinase GQZ26_14800 ENOG4108ZF3 Phosphatase GQZ26_14810 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B GQZ26_14820 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) GQZ26_14825 ENOG4105C25 Primosomal protein n' GQZ26_14830 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase GQZ26_14850 ENOG4105DSJ YicC domain protein GQZ26_14865 ENOG4105DC7 peptidase M24 GQZ26_14950 ENOG4105C34 Pseudouridine synthase GQZ26_14975 ENOG4105DBK s4 domain protein GQZ26_14980 ENOG41067XK integral membrane protein GQZ26_14990 ENOG4105DFA alanine racemase domain protein GQZ26_14995 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase GQZ26_15000 ENOG4105WR5 sporulation protein, YlmC YmxH family GQZ26_15010 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GQZ26_15020 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) GQZ26_15025 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) GQZ26_15045 ENOG4105CNI cell division protein FtsW GQZ26_15060 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) GQZ26_15065 ENOG4105CJN penicillin-binding protein GQZ26_15070 ENOG4105CJN penicillin-binding protein GQZ26_15075 ENOG41068DC Essential cell division protein (By similarity) GQZ26_15110 ENOG4105KNH Nucleic acid-binding protein GQZ26_15235 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) GQZ26_15245 ENOG4105CAR Terminase, large subunit GQZ26_15355 ENOG4108IMY Transcriptional regulator GQZ26_15380 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) GQZ26_15390 ENOG41063PX domain protein GQZ26_15395 ENOG4105D78 K07001 NTE family protein GQZ26_15400 ENOG4105H20 Sporulation integral membrane protein YlbJ GQZ26_15410 ENOG4106H78 methyltransferase GQZ26_15440 ENOG4107TB6 phosphoglycerate mutase GQZ26_15455 ENOG4106UY4 Inherit from COG: Scp-like extracellular GQZ26_15470 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_15515 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) GQZ26_15520 ENOG4105CNI cell division protein FtsW GQZ26_15535 ENOG4108IAB Phoh family GQZ26_15555 ENOG4105QA2 GQZ26_15560 ENOG4105CI3 gtp-binding protein typa GQZ26_15570 ENOG4105ECY inositol monophosphatase GQZ26_15590 ENOG4105CXN decarboxylase GQZ26_15640 ENOG4105CPP Dehydrogenase, E1 component GQZ26_15655 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) GQZ26_15660 ENOG4108X4Q Hydrolase GQZ26_15670 ENOG4105CN5 Metallo-Beta-Lactamase GQZ26_15675 ENOG4107ZYR domain protein GQZ26_15710 ENOG4108XRC Protein of unknown function (DUF458) GQZ26_15715 ENOG4107IN1 Protein of unknown function (DUF1797) GQZ26_15730 ENOG4105EPM Diguanylate phosphodiesterase GQZ26_15735 ENOG4105K6S Short-chain dehydrogenase reductase Sdr GQZ26_15750 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) GQZ26_15760 ENOG4105UIN GQZ26_15820 ENOG4108HGU Histidine kinase GQZ26_15830 ENOG4105CHM Aminotransferase GQZ26_15835 ENOG4105FKQ transcriptional regulator GQZ26_15840 ENOG4105EG2 ABC transporter, permease GQZ26_15850 ENOG4107FKK extracellular solute-binding protein family 1 GQZ26_15860 ENOG4105CG3 alpha amylase, catalytic region GQZ26_15905 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) GQZ26_15940 ENOG4105K7K Transcriptional regulator GQZ26_15945 ENOG4105DTD Dehydrogenase GQZ26_15965 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase GQZ26_16005 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GQZ26_16015 ENOG4106TD9 Diguanylate cyclase GQZ26_16035 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) GQZ26_16050 ENOG4105CID antiterminator GQZ26_16060 ENOG4105FDP GntR family transcriptional regulator GQZ26_16070 ENOG4105CE4 GlcNAc 6-P deacetylase GQZ26_16105 ENOG4107ZE5 PPIases accelerate the folding of proteins GQZ26_16110 ENOG4105PTM secreted protein GQZ26_16115 ENOG4105J7I hydrolase GQZ26_16125 ENOG4105G6R Stage v sporulation protein ae GQZ26_16135 ENOG4105CZ3 stage V sporulation protein ad GQZ26_16140 ENOG41090VF Stage v sporulation protein ac GQZ26_16160 ENOG4105C8J )-transporter GQZ26_16165 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GQZ26_16175 ENOG41082AN stage II sporulation protein GQZ26_16180 ENOG4105DZ1 carboxypeptidase GQZ26_16185 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family GQZ26_16190 ENOG4105DVE abc transporter atp-binding protein GQZ26_16220 ENOG4105D7N magnesium and cobalt transport protein CorA GQZ26_16250 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GQZ26_16260 ENOG4105I3K Ferric uptake regulator, Fur family GQZ26_16265 ENOG4105MZ9 stage II sporulation protein m GQZ26_16285 ENOG4105CPC Aldo Keto reductase GQZ26_16295 ENOG4105RHY Pfam:UPF0157 GQZ26_16315 ENOG4107SKW Inherit from COG: Alpha beta hydrolase GQZ26_16325 ENOG4105ETE Transcriptional regulator (LacI family GQZ26_16330 ENOG4108YM7 Gcn5-related n-acetyltransferase GQZ26_16350 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) GQZ26_16355 ENOG4108R6K riboflavin synthase, subunit alpha GQZ26_16380 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) GQZ26_16385 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) GQZ26_16400 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) GQZ26_16410 ENOG4105DFD Na H antiporter GQZ26_16415 ENOG4105CGH 5'-nucleotidase GQZ26_16470 ENOG4108IXY short-chain dehydrogenase reductase GQZ26_16480 ENOG4105II7 pyrroline-5-carboxylate reductase GQZ26_16485 ENOG4105EJQ L-serine dehydratase GQZ26_16510 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) GQZ26_16520 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) GQZ26_16525 ENOG4105D9U N-acetyltransferase GQZ26_16540 ENOG4108VZI ErfK ybiS ycfS ynhG family protein GQZ26_16545 ENOG4108QEG Membrane GQZ26_16550 ENOG4105CDA abc transporter atp-binding protein GQZ26_16555 ENOG4105E5Q amino acid AbC transporter GQZ26_16560 ENOG4108HW3 (ABC) transporter GQZ26_16575 ENOG4108QY0 Membrane GQZ26_16585 ENOG4105C7S Dehydrogenase GQZ26_16590 ENOG4105CPP Dehydrogenase, E1 component GQZ26_16610 ENOG4107RDP Dehydrogenase GQZ26_16620 ENOG4108JUB Transcriptional regulator GQZ26_16630 ENOG4108QXE glycerophosphoryl diester phosphodiesterase GQZ26_16640 ENOG4107QQR Sporulation GQZ26_16645 ENOG4105S1Z Stage IV sporulation protein B GQZ26_16650 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) GQZ26_16660 ENOG4105DX0 Hemolysin A GQZ26_16670 ENOG4105CTB Polyprenyl synthetase GQZ26_16695 ENOG4108ZSR alkaline shock protein GQZ26_16700 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase GQZ26_16725 ENOG410644B Stage III sporulation protein af GQZ26_16735 ENOG4105KQ4 Stage iii sporulation protein ad GQZ26_16740 ENOG4108CQH stage III sporulation protein AC GQZ26_16745 ENOG4105KR5 Stage iii sporulation protein GQZ26_16750 ENOG4105CD2 stage iii sporulation protein aa GQZ26_16775 ENOG4105DC7 peptidase M24 GQZ26_16790 ENOG4105CBJ Metal-dependent enzyme GQZ26_16830 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) GQZ26_16835 ENOG4105WZW rhodanese family GQZ26_16855 ENOG41080TC multidrug resistance protein GQZ26_16890 ENOG4105CJ1 ABC, transporter GQZ26_16895 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family GQZ26_16925 ENOG4105C0D helicase GQZ26_17005 ENOG4108FPN Integrase GQZ26_17010 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GQZ26_17015 ENOG4105ZX1 Transposase C GQZ26_17065 ENOG4105C3R Methionine synthase GQZ26_17075 ENOG4105C28 cystathionine GQZ26_17080 ENOG4105C28 cystathionine GQZ26_17100 ENOG4105C5X domain protein GQZ26_17110 ENOG4105DKQ ROK family GQZ26_17120 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase GQZ26_17135 ENOG4108UTW Plays a role in the regulation of phosphate uptake GQZ26_17140 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) GQZ26_17145 ENOG4105E2Z phosphate ABC transporter (Permease GQZ26_17155 ENOG4105PWN phosphate abc transporter GQZ26_17160 ENOG4107RF6 penicillin-binding protein GQZ26_17170 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GQZ26_17195 ENOG4105N80 Ferric uptake regulator, Fur family GQZ26_17205 ENOG4105FDK ABC transporter GQZ26_17210 ENOG4108JYZ YitT family GQZ26_17215 ENOG41069ZM Protein of unknown function (DUF2624) GQZ26_17240 ENOG4105EGD dinuclear metal center protein, YbgI family GQZ26_17255 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GQZ26_17260 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) GQZ26_17290 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) GQZ26_17295 ENOG4105KG3 cytidine deaminase GQZ26_17300 ENOG4107YR5 Diacylglycerol kinase GQZ26_17325 ENOG41068P3 sporulation protein YqfC GQZ26_17330 ENOG4105KTH gatB Yqey GQZ26_17340 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) GQZ26_17345 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) GQZ26_17375 ENOG4105CSA Coproporphyrinogen iii oxidase GQZ26_17380 ENOG4105KVH Transcriptional regulator GQZ26_17405 ENOG4105TQK DNA polymerase iii, delta' subunit GQZ26_17415 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 GQZ26_17420 ENOG4108UK2 deaminase GQZ26_17425 ENOG4105KQC Competence protein GQZ26_17435 ENOG4105DXX methyltransferase GQZ26_17445 ENOG4108WF2 Metal Dependent Phosphohydrolase GQZ26_17455 ENOG410812S Rna-binding protein GQZ26_17465 ENOG4105CQW ribosome biogenesis GTPase YqeH GQZ26_17470 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase GQZ26_17485 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GQZ26_17515 ENOG4105G6Z alkaline phosphatase GQZ26_17520 ENOG4105KEG ribosomal-protein-alanine acetyltransferase GQZ26_17525 ENOG4108MUZ hydrolase GQZ26_17560 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin GQZ26_17565 ENOG4105MIR Phenylalanine 4-monooxygenase GQZ26_17575 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase GQZ26_17620 ENOG4108HUF Transporter GQZ26_17630 ENOG4108EKI Dehydrogenase GQZ26_17635 ENOG4105C28 cystathionine GQZ26_17665 ENOG4107XRG penicillin-binding protein GQZ26_17680 ENOG4105CFP Peptidase U32 GQZ26_17685 ENOG4105XYU peptidase (U32 family) GQZ26_17690 ENOG4108VQJ O-methyltransferase GQZ26_17695 ENOG4105HHA aminodeoxychorismate lyase GQZ26_17725 ENOG4105C02 permease GQZ26_17740 ENOG41060CR GQZ26_17745 ENOG4105C7H Helicase, RecD TraA family GQZ26_17760 ENOG4105C3J Cysteine desulfurase GQZ26_17770 ENOG4105D1H recombination factor protein RarA GQZ26_17775 ENOG4108VCI transcription factor, rsfa family GQZ26_17780 ENOG4105CUZ uba thif-type nad fad binding protein GQZ26_17805 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) GQZ26_17815 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) GQZ26_17820 ENOG41076HS cation diffusion facilitator family transporter GQZ26_17825 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) GQZ26_17835 ENOG4105CKP Polysaccharide Biosynthesis Protein GQZ26_17840 ENOG4108QG2 Membrane GQZ26_17850 ENOG4105VIE preprotein translocase, subunit YajC GQZ26_17865 ENOG41061AI Protein of unknown function (DUF2905) GQZ26_17905 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase GQZ26_17910 ENOG4108IYU L-aspartate oxidase GQZ26_17925 ENOG4108RPX mosc domain containing protein GQZ26_17930 ENOG4105CQC Prephenate dehydratase GQZ26_17950 ENOG4105EWM Histidine kinase GQZ26_17980 ENOG4105C03 ribonuclease GQZ26_17995 ENOG4107QMS site-determining protein GQZ26_18010 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) GQZ26_18015 ENOG4105DFF Rod shape-determining protein mreb GQZ26_18035 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase GQZ26_18060 ENOG41068KH stage VI sporulation protein D GQZ26_18070 ENOG4105D52 delta-aminolevulinic acid dehydratase GQZ26_18095 ENOG4105K56 Transcriptional regulator GQZ26_18115 ENOG4108IUQ atp-dependent protease GQZ26_18145 ENOG4108QCI YvbH-like oligomerisation region GQZ26_18170 ENOG4105M59 Phosphodiesterase, mj0936 family GQZ26_18175 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) GQZ26_18185 ENOG4108XJQ germination protein GQZ26_18195 ENOG4108PCX Major Facilitator GQZ26_18205 ENOG4105KBX Transcriptional regulator, TetR family GQZ26_18220 ENOG4105PFC Transcriptional regulator GQZ26_18230 ENOG4105DZC cytosine deaminase GQZ26_18235 ENOG41067S9 phage shock protein C, PspC GQZ26_18240 ENOG4108JCI Transcriptional regulator GQZ26_18250 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) GQZ26_18255 ENOG4108Z40 Transcriptional regulator GQZ26_18260 ENOG4105RHA ABC transporter, permease GQZ26_18265 ENOG4108IUX (ABC) transporter GQZ26_18270 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family GQZ26_18275 ENOG4105ER2 Ompa motb domain protein GQZ26_18280 ENOG4105E14 MotA TolQ exbB proton channel GQZ26_18285 ENOG4108VXD carboxy-peptidase GQZ26_18295 ENOG4105E33 succinate dehydrogenase GQZ26_18305 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit GQZ26_18320 ENOG4105K63 Thioredoxin GQZ26_18325 ENOG4105C10 Electron transfer flavoprotein GQZ26_18330 ENOG4105BZJ Electron transfer flavoprotein GQZ26_18335 ENOG41060WC Enoyl-CoA hydratase GQZ26_18340 ENOG4107Z3H Transcriptional regulator, TetR family GQZ26_18345 ENOG4105CEY Amp-dependent synthetase and ligase GQZ26_18385 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GQZ26_18395 ENOG4105DR4 Methyltransferase GQZ26_18410 ENOG4105KFN sortase, SrtB family GQZ26_18415 ENOG4105E0A ABC, transporter GQZ26_18430 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) GQZ26_18435 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) GQZ26_18445 ENOG4105FE9 pseudouridine synthase GQZ26_18455 ENOG4105DCG PHP domain protein GQZ26_18505 ENOG4108RWN rrna methyltransferase GQZ26_18525 ENOG4105C0R drug resistance transporter emrb qaca subfamily GQZ26_18530 ENOG4105CW7 secretion protein, HlyD family GQZ26_18535 ENOG4108JGH Tetr family transcriptional regulator GQZ26_18540 ENOG4105CN9 Peptidase m42 family protein GQZ26_18560 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) GQZ26_18565 ENOG4105C22 threonyL-tRNA synthetase GQZ26_18570 ENOG4108TDW sporulation protein YtxC GQZ26_18590 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) GQZ26_18600 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase GQZ26_18605 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) GQZ26_18620 ENOG4105C2M dna polymerase I GQZ26_18625 ENOG4105BZU Histidine kinase GQZ26_18630 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GQZ26_18650 ENOG4108HMX isocitrate dehydrogenase (NADP) GQZ26_18655 ENOG4105BZN citrate synthase GQZ26_18665 ENOG4108REF Sporulation integral membrane protein ytvi GQZ26_18670 ENOG4105FS0 cytoplasmic membrane protein GQZ26_18695 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family GQZ26_18700 ENOG4105C6K Malic enzyme GQZ26_18705 ENOG4105C0B DNA polymerase III (alpha subunit) GQZ26_18710 ENOG4105VV2 GQZ26_18720 ENOG4105SFS phosphoesterase RecJ domain protein GQZ26_18755 ENOG4105DC7 peptidase M24 GQZ26_18795 ENOG41082W1 Cupin 2, conserved barrel domain protein GQZ26_18815 ENOG4107YZX Universal stress protein GQZ26_18875 ENOG4108JYZ YitT family GQZ26_18905 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) GQZ26_18910 ENOG4105KBJ sporulation protein ytfj GQZ26_18925 ENOG4105EFZ amidohydrolase GQZ26_18935 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) GQZ26_18960 ENOG4105C5Q Transcriptional regulator GQZ26_18970 ENOG4105U5Y Transcriptional regulator GQZ26_18980 ENOG4105C28 cystathionine GQZ26_19010 ENOG4105EMN RNA polymerase sigma factor GQZ26_19030 ENOG4105F1V Acetoin utilization protein GQZ26_19035 ENOG4105W87 Cbs domain GQZ26_19055 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GQZ26_19065 ENOG4105EP9 oxidoreductase GQZ26_19095 ENOG4105ETE Transcriptional regulator (LacI family GQZ26_19115 ENOG4105C88 aminopeptidase GQZ26_19160 ENOG4108VDD TRNA binding domain protein GQZ26_19190 ENOG4105C8F Beta-lactamase domain protein GQZ26_19205 ENOG4108V15 phosphotransferase enzyme family GQZ26_19210 ENOG4108IUM Glycogen debranching enzyme GQZ26_19220 ENOG4107QSE Dipeptidase GQZ26_19225 ENOG4105YW5 deoR family transcriptional regulator GQZ26_19240 ENOG4105CBX hi0933 family GQZ26_19275 ENOG4108VJ1 Transcriptional regulator (CarD family GQZ26_19280 ENOG4107EXU Short-chain dehydrogenase reductase Sdr GQZ26_19300 ENOG4108ZAF Molybdopterin GQZ26_19305 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein GQZ26_19310 ENOG4105CVM Molybdenum cofactor synthesis domain protein GQZ26_19320 ENOG4105D06 uba thif-type nad fad binding protein GQZ26_19325 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) GQZ26_19345 ENOG41085GJ domain protein GQZ26_19355 ENOG4105DWV Homoserine O-trans-acetylase GQZ26_19365 ENOG4108B31 Spore germination protein GQZ26_19395 ENOG410605W Major Facilitator GQZ26_19400 ENOG4107S91 Sodium hydrogen exchanger GQZ26_19405 ENOG4105NCW Trka-c domain protein GQZ26_19420 ENOG4105C19 ABC transporter GQZ26_19440 ENOG4105N5T Radical SAM Protein GQZ26_19450 ENOG4105CIG ABC transporter GQZ26_19485 ENOG4105E8V Alpha Beta Hydrolase Fold protein GQZ26_19490 ENOG4108Z0R Transferase GQZ26_19495 ENOG4105YVM Phosphoesterase, PA-phosphatase related GQZ26_19500 ENOG4105BZF Glycosyl transferase (Group 1 GQZ26_19510 ENOG4108RIR Molybdenum cofactor biosynthesis protein GQZ26_19520 ENOG4108MK9 spermidine N(1)-acetyltransferase GQZ26_19565 ENOG4105BZU Histidine kinase GQZ26_19570 ENOG4105BZU Histidine kinase GQZ26_19575 ENOG4107S9D Alpha beta hydrolase GQZ26_19580 ENOG4107T7U Sulfatase GQZ26_19600 ENOG4105D2X ABC transporter substrate-binding protein GQZ26_19610 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component GQZ26_19665 ENOG4108V2W Carbonate dehydratase GQZ26_19670 ENOG4105C4M (Ubiquinol oxidase) subunit I GQZ26_19675 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GQZ26_19720 ENOG41087YS Phage shock protein A GQZ26_19755 ENOG4105BZU Histidine kinase GQZ26_19760 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GQZ26_19790 ENOG4108UGV hypoxanthine phosphoribosyltransferase GQZ26_19795 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) GQZ26_19820 ENOG4105C19 ABC transporter GQZ26_19835 ENOG4107ZTW SNARE associated Golgi GQZ26_19860 ENOG4105C19 ABC transporter GQZ26_19865 ENOG41086D8 Transcriptional regulator GQZ26_19875 ENOG41082BM Transcriptional regulator, arsr family GQZ26_19915 ENOG4105C6Z Gluconate GQZ26_19920 ENOG4105FDP GntR family transcriptional regulator GQZ26_19940 ENOG41069H0 dihydroorotase EC 3.5.2.3 GQZ26_19960 ENOG4105DTQ mandelate racemase muconate lactonizing GQZ26_19970 ENOG4108IPT Naphthoate synthase GQZ26_19975 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) GQZ26_19985 ENOG4105E4F Isochorismate synthase GQZ26_19990 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase GQZ26_20000 ENOG4105VEQ Cold shock protein GQZ26_20045 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin GQZ26_20145 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation GQZ26_20180 ENOG4105KT7 mgtC SapB transporter GQZ26_20185 ENOG4107PBV potassium channel GQZ26_20200 ENOG4105WG9 Conserved Protein GQZ26_20210 ENOG4105CHM Aminotransferase GQZ26_20215 ENOG4108ZB6 transcriptional regulator AsnC family GQZ26_20220 ENOG4105C5I Dehydrogenase GQZ26_20225 ENOG4108MUZ hydrolase GQZ26_20235 ENOG4105C87 Aminotransferase class I and II GQZ26_20245 ENOG4105Y38 Kinase-associated protein B GQZ26_20255 ENOG4107R3E Citrate transporter GQZ26_20270 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) GQZ26_20275 ENOG4105KA0 thioesterase Superfamily protein GQZ26_20295 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase GQZ26_20315 ENOG41069ER domain protein GQZ26_20330 ENOG4105CEP NADH dehydrogenase GQZ26_20355 ENOG4105EWC Purine nucleoside phosphorylase GQZ26_20375 ENOG4108YX9 iron--sulfur cluster insertion protein erpA GQZ26_20400 ENOG4108JJA ABC, transporter GQZ26_20410 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA GQZ26_20455 ENOG41083MR nifu domain-containing protein GQZ26_20470 ENOG4108W5N phosphatidylglycerophosphatase a GQZ26_20480 ENOG4105DYS nad(p)h dehydrogenase (quinone) GQZ26_20485 ENOG4105D4U had-superfamily hydrolase, subfamily iia GQZ26_20500 ENOG4105CBT Fructose-1,6-bisphosphatase GQZ26_20515 ENOG4105MMD transcriptional regulator GQZ26_20520 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) GQZ26_20525 ENOG4107TXC Transcriptional regulator GQZ26_20530 ENOG41090T1 Membrane GQZ26_20565 ENOG4105KZD Domain of unknown function (DUF1805) GQZ26_20570 ENOG4107R8B 5'-nucleotidase GQZ26_20575 ENOG4105DIW FeS assembly protein SUFB GQZ26_20580 ENOG4108UNV SUF system FeS assembly protein, NifU family GQZ26_20585 ENOG4105C9B Cysteine desulfurase GQZ26_20590 ENOG4105JRK feS assembly protein SufD GQZ26_20595 ENOG4105C3K feS assembly ATPase SufC GQZ26_20600 ENOG4105D01 (LipO)protein GQZ26_20605 ENOG4105D01 (LipO)protein GQZ26_20610 ENOG4108UMI ABC transporter, permease GQZ26_20640 ENOG41080E8 Transcriptional regulator, Spx MgsR family GQZ26_20710 ENOG4108W8B Beta-lactamase domain protein GQZ26_20715 ENOG4105C1G acyl-Coa dehydrogenase GQZ26_20725 ENOG4105CHU acetyl-coa acetyltransferase GQZ26_20760 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer GQZ26_20765 ENOG4105D7V transposase GQZ26_20780 ENOG4105F27 Major Facilitator GQZ26_20785 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) GQZ26_20795 ENOG4107R7I amino acid GQZ26_20820 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins GQZ26_20830 ENOG4107AYK membrAne GQZ26_20865 ENOG4107ZTW SNARE associated Golgi GQZ26_20875 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GQZ26_20880 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GQZ26_20885 ENOG4105BZU Histidine kinase GQZ26_20910 ENOG4105C8Q Methyl-accepting chemotaxis GQZ26_20915 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer GQZ26_20920 ENOG4105VG1 fes assembly suf system protein GQZ26_20925 ENOG4105D4Y metalloprotease GQZ26_20945 ENOG4107S91 Sodium hydrogen exchanger GQZ26_20950 ENOG4105NCW Trka-c domain protein GQZ26_20960 ENOG4108RMU ferritin dps family protein GQZ26_20980 ENOG4108URH decarboxylase GQZ26_21000 ENOG4105D9N nucleoside GQZ26_21005 ENOG4105D9N nucleoside GQZ26_21020 ENOG4108RYK Nad-dependent epimerase dehydratase GQZ26_21035 ENOG4105CV8 reductase GQZ26_21040 ENOG4105F27 Major Facilitator GQZ26_21045 ENOG4105KVH Transcriptional regulator GQZ26_21060 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) GQZ26_21065 ENOG4105D4A Cell wall formation (By similarity) GQZ26_21090 ENOG4105C8Q Methyl-accepting chemotaxis GQZ26_21100 ENOG4105WMR Protein CrcB homolog GQZ26_21125 ENOG4105C5H ABC transporter GQZ26_21130 ENOG4108MK9 spermidine N(1)-acetyltransferase GQZ26_21135 ENOG4108VY7 phosphate-starvation-inducible protein PsiE GQZ26_21145 ENOG4108IPW abc transporter atp-binding protein GQZ26_21150 ENOG4105CM4 permease protein GQZ26_21175 ENOG4105C19 ABC transporter GQZ26_21195 ENOG4107ZTW SNARE associated Golgi GQZ26_21240 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) GQZ26_21245 ENOG41086D8 Transcriptional regulator GQZ26_21260 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) GQZ26_21265 ENOG4105C0R drug resistance transporter emrb qaca subfamily GQZ26_21275 ENOG4108ZHR arsR family transcriptional regulator GQZ26_21280 ENOG4105DHF Membrane GQZ26_21320 ENOG4107RBB ABC transporter, permease GQZ26_21325 ENOG4105C19 ABC transporter GQZ26_21375 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) GQZ26_21385 ENOG4105XZU Preprotein translocase, subunit SecG GQZ26_21390 ENOG41067MG lrgb family GQZ26_21440 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GQZ26_21460 ENOG41090VF Stage v sporulation protein ac GQZ26_21465 ENOG4105CZ3 stage V sporulation protein ad GQZ26_21480 ENOG4108QY0 Membrane GQZ26_21485 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) GQZ26_21490 ENOG4105KRI phosphocarrier protein (HPr GQZ26_21500 ENOG4105CHW UPF0052 protein GQZ26_21510 ENOG4108Z4K mutator MutT protein GQZ26_21520 ENOG4105C3M thioredoxin reductase GQZ26_21530 ENOG4108S4C acetyltransferase GQZ26_21550 ENOG41086DT Membrane protein of unknown function GQZ26_21560 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) GQZ26_21575 ENOG4107TXC Transcriptional regulator GQZ26_21610 ENOG4105DUM transcriptional regulator, lysR family GQZ26_21620 ENOG4108WS4 fmn reductase GQZ26_21625 ENOG4105C5H ABC transporter GQZ26_21635 ENOG4105BZ1 (ABC) transporter GQZ26_21645 ENOG4105CN1 protease GQZ26_21650 ENOG4105CRP Part of the ABC transporter FtsEX involved in GQZ26_21655 ENOG4105CAK Cell division ATP-binding protein ftsE GQZ26_21665 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) GQZ26_21675 ENOG4105MS2 ribosomal subunit Interface protein GQZ26_21680 ENOG4105VEQ Cold shock protein GQZ26_21685 ENOG41081UC Inherit from COG: Competence protein GQZ26_21695 ENOG4105K4H Nlp p60 protein GQZ26_21700 ENOG4105KVH Transcriptional regulator GQZ26_21710 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein GQZ26_21715 ENOG4108KGH TRANSCRIPTIONal GQZ26_21720 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase GQZ26_21725 ENOG4105C6Y Udp-glucose 6-dehydrogenase GQZ26_21730 ENOG4105ESV Glycosyl transferase, family 4 GQZ26_21740 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GQZ26_21760 ENOG4105F8D glycoside hydrolase family 4 GQZ26_21765 ENOG4105VCP PTS System GQZ26_21770 ENOG4105CK1 PTS System GQZ26_21780 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) GQZ26_21800 ENOG4105VCP PTS System GQZ26_21810 ENOG4105VZJ PTS System GQZ26_21825 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase GQZ26_21845 ENOG4105ECB domain protein GQZ26_21850 ENOG4107RSM transcriptional regulator GQZ26_21880 ENOG4105DAA L-lactate GQZ26_21890 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) GQZ26_21900 ENOG4105E0M Sulfatase GQZ26_21925 ENOG4107R8N Glycosyl transferase, family 2 GQZ26_21930 ENOG4105C94 Transporter GQZ26_21935 ENOG41069ER domain protein GQZ26_21960 ENOG4105KBK Zinc finger, swim domain protein GQZ26_21965 ENOG4105C0D helicase GQZ26_21995 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GQZ26_22005 ENOG4107RBB ABC transporter, permease GQZ26_22010 ENOG4105C19 ABC transporter GQZ26_22020 ENOG4105CXY transporter GQZ26_22035 ENOG4105BZU Histidine kinase GQZ26_22040 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GQZ26_22050 ENOG4108KGH TRANSCRIPTIONal GQZ26_22060 ENOG4105C6Y Udp-glucose 6-dehydrogenase GQZ26_22095 ENOG4105D3Q Sugar transferase GQZ26_22100 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase GQZ26_22110 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase GQZ26_22115 ENOG4108RB3 Capsular polysaccharide biosynthesis protein GQZ26_22120 ENOG4107YJ4 chain length determinant protein GQZ26_22125 ENOG4105HTX biosynthesis protein GQZ26_22130 ENOG4108QV3 biosynthesis protein GQZ26_22145 ENOG4105MT0 Sporulation transcriptional regulator spoiiid GQZ26_22155 ENOG4105FRN stage II sporulation protein GQZ26_22170 ENOG4105DY9 regulatoR GQZ26_22190 ENOG4106778 Protein of unknown function (DUF1146) GQZ26_22195 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GQZ26_22200 ENOG4105C8S subunit m GQZ26_22205 ENOG4105D65 subunit l GQZ26_22235 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain GQZ26_22245 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain GQZ26_22250 ENOG4105BZU Histidine kinase GQZ26_22300 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) GQZ26_22305 ENOG41062M3 atp synthase GQZ26_22335 ENOG4108YZG isomerase GQZ26_22350 ENOG4108VGI doxx family GQZ26_22355 ENOG4107XC4 flavin reductase domain protein, FMN-binding GQZ26_22370 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) GQZ26_22380 ENOG4108ZXQ stage ii sporulation protein r GQZ26_22385 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) GQZ26_22390 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) GQZ26_22405 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) GQZ26_22410 ENOG4105CBT Fructose-1,6-bisphosphatase GQZ26_22415 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) GQZ26_22450 ENOG4105C1G acyl-Coa dehydrogenase GQZ26_22455 ENOG4105C1G acyl-Coa dehydrogenase GQZ26_22460 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase GQZ26_22470 ENOG4105DF6 Fe-S oxidoreductase GQZ26_22485 ENOG4105BZU Histidine kinase GQZ26_22510 ENOG4105BZU Histidine kinase GQZ26_22515 ENOG4105KCT ABC transporter GQZ26_22520 ENOG4108M15 ABC transporter GQZ26_22525 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) GQZ26_22535 ENOG4105IIU Aminopeptidase GQZ26_22555 ENOG4105EMN RNA polymerase sigma factor GQZ26_22565 ENOG410684U Domain of unknown function (DUF1934) GQZ26_22585 ENOG4105CYW agmatinase GQZ26_22595 ENOG4105DXB Major Facilitator superfamily GQZ26_22605 ENOG4108QXE glycerophosphoryl diester phosphodiesterase GQZ26_22610 ENOG4105BZ4 penicillin-binding protein GQZ26_22615 ENOG4108XFG YwhD family GQZ26_22620 ENOG4108Z4T Peptidase M50 GQZ26_22625 ENOG41069HH 4-oxalocrotonate tautomerase GQZ26_22630 ENOG4105DCI Phosphohydrolase GQZ26_22635 ENOG4108V5C ABC transporter GQZ26_22640 ENOG4105E0A ABC, transporter GQZ26_22645 ENOG4105EHG Permease protein GQZ26_22650 ENOG4105DQ5 transport system permease protein GQZ26_22660 ENOG4108VCI transcription factor, rsfa family GQZ26_22675 ENOG4108IJ2 phosphate acetyltransferase GQZ26_22690 ENOG4108VKI Cell wall hydrolase GQZ26_22710 ENOG4107SVH Potassium channel protein GQZ26_22720 ENOG410667J hydrolase GQZ26_22725 ENOG4105VCH membrane GQZ26_22735 ENOG4108TU7 Inherit from COG: (ABC) transporter GQZ26_22740 ENOG4105CJ1 ABC, transporter GQZ26_22745 ENOG41090WU lipolytic protein G-D-S-L family GQZ26_22760 ENOG4105D6E homoserine dehydrogenase GQZ26_22785 ENOG4108Y4K DNA-binding transcriptional activator GQZ26_22795 ENOG4105WH1 Two component transcriptional regulator luxr family GQZ26_22800 ENOG4105BZU Histidine kinase GQZ26_22805 ENOG4105DWF phosphomethylpyrimidine kinase GQZ26_22815 ENOG4105VCD cytoplasmic protein GQZ26_22820 ENOG4105D22 carbon starvation protein GQZ26_22825 ENOG4105DY9 regulatoR GQZ26_22830 ENOG41079KZ Major Facilitator Superfamily GQZ26_22840 ENOG4105CG5 Glycosyl transferase (Group 1 GQZ26_22850 ENOG4105EN6 Membrane GQZ26_22865 ENOG4108S4H thioesterase Superfamily protein GQZ26_22870 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) GQZ26_22885 ENOG4105K64 Glycosyl transferase, family 2 GQZ26_22900 ENOG4105C5H ABC transporter GQZ26_22905 ENOG41067SE Tetr family transcriptional regulator GQZ26_22915 ENOG4105E0X reductase GQZ26_22920 ENOG4106F5Q Membrane GQZ26_22935 ENOG4105DY9 regulatoR GQZ26_22940 ENOG4108HRK Histidine kinase GQZ26_22945 ENOG4107RGD Major Facilitator superfamily GQZ26_22960 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GQZ26_22970 ENOG4105IW1 AmiS UreI transporter GQZ26_23000 ENOG4105CMR udp-glucose 4-epimerase GQZ26_23005 ENOG4108UT2 hemolysin iii GQZ26_23015 ENOG4105C1J atp-dependent rna helicase GQZ26_23025 ENOG4105DPN Oligoendopeptidase f GQZ26_23045 ENOG4105C0H protease GQZ26_23050 ENOG4105Q2H domain protein GQZ26_23065 ENOG4105BZU Histidine kinase GQZ26_23070 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GQZ26_23100 ENOG4105CDU Replicative dna helicase GQZ26_23110 ENOG4105BZR domain protein GQZ26_23115 ENOG4108XMW Membrane GQZ26_23125 ENOG4108UUM single-stranded DNA-binding protein GQZ26_23135 ENOG4105C3G gtp-binding protein GQZ26_23140 ENOG4105VDK protein, conserved in bacteria GQZ26_23145 ENOG4105D8X mechanosensitive ion channel GQZ26_23150 ENOG4108ZDA Sporulation protein YyaC GQZ26_23155 ENOG4105FA0 parb-like partition protein GQZ26_23160 ENOG4107QJE Chromosome Partitioning Protein GQZ26_23190 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins GQZ26_23210 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) GQZ26_23215 ENOG410848D S4 domain protein YaaA GQZ26_23230 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GQZ26_23265 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) GQZ26_23300 ENOG4105ZMH deoxynucleoside kinase GQZ26_23310 ENOG4105GTG Isochorismatase GQZ26_23315 ENOG4108Z6B deaminase GQZ26_23325 ENOG4105C6E dna polymerase iii GQZ26_23345 ENOG41067KS pro-sigma K processing GQZ26_23380 ENOG4105CXN decarboxylase GQZ26_23390 ENOG4105FA2 dna polymerase iii GQZ26_23395 ENOG4105MA4 psp1 domain protein GQZ26_23405 ENOG41060K3 Methyltransferase GQZ26_23415 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) GQZ26_23420 ENOG4105KRN Transcriptional regulator, abrb family GQZ26_23430 ENOG4105F8V Hydrolase, tatD family GQZ26_23435 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) GQZ26_23445 ENOG4105XFA sporulation peptidase YabG GQZ26_23450 ENOG4105W42 Veg protein GQZ26_23465 ENOG4105DFT pur operon repressor GQZ26_23470 ENOG4105KME endoribonuclease L-psp GQZ26_23485 ENOG4105C5T Phosphoribosyl pyrophosphate synthase GQZ26_23500 ENOG4108JA2 transcriptioN-repair coupling factor GQZ26_23505 ENOG4108M14 stage v sporulation protein t GQZ26_23515 ENOG4108IY2 MazG family GQZ26_23520 ENOG41082I2 s4 domain protein GQZ26_23525 ENOG4105VYY sporulation protein yabp GQZ26_23540 ENOG41060GV RNA binding s1 domain protein GQZ26_23565 ENOG4108UGV hypoxanthine phosphoribosyltransferase GQZ26_23570 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) GQZ26_23585 ENOG4105C6T cysteine synthase GQZ26_23590 ENOG4105CRQ synthase (Component I) GQZ26_23595 ENOG4105DDQ anthranilate synthase GQZ26_23600 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 GQZ26_23605 ENOG4105EEI dihydropteroate synthase GQZ26_23610 ENOG4105KRF dihydroneopterin aldolase GQZ26_23615 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase GQZ26_23625 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) GQZ26_23715 ENOG4108Z0C Uvrb UvrC protein GQZ26_23740 ENOG4105CTP PilT protein domain protein GQZ26_23760 ENOG4105D7W serine acetyltransferase GQZ26_23775 ENOG4105C2N RNA methyltransferase TrmH family group 3 GQZ26_23780 ENOG4105M0M Tetracycline resistance protein GQZ26_23785 ENOG4105QIV RNA polymerase GQZ26_23800 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) GQZ26_23825 ENOG4107Y49 methyltransferase GQZ26_23840 ENOG4105XPM ribosomal protein GQZ26_23945 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) GQZ26_23970 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) GQZ26_23980 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) GQZ26_23990 ENOG41067V7 50S ribosomal protein L36 GQZ26_24020 ENOG4108JJB ABC transporter GQZ26_24025 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) GQZ26_24055 ENOG4105D1F ATP-binding protein GQZ26_24070 ENOG4108NMV polysaccharide deacetylase GQZ26_24150 ENOG4105C8B TIGR00159 family GQZ26_24155 ENOG4107U5W ybbr family GQZ26_24175 ENOG4108VQT Alpha beta hydrolase fold protein GQZ26_24185 ENOG4105CMG Carbohydrate kinase GQZ26_24195 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) GQZ26_24230 ENOG4108PSK reductase GQZ26_24235 ENOG4108UMI ABC transporter, permease GQZ26_24245 ENOG4105D01 (LipO)protein GQZ26_24250 ENOG4105EE1 crotonyl-CoA reductase GQZ26_24260 ENOG4105IQ5 FAD linked oxidase domain protein GQZ26_24290 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GQZ26_24295 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GQZ26_24300 ENOG4105C3U ABC transporter GQZ26_24305 ENOG4108JQ7 (ABC) transporter GQZ26_24325 ENOG4108J59 Extracellular solute-binding protein, family 5 GQZ26_24330 ENOG4108J59 Extracellular solute-binding protein, family 5 GQZ26_24345 ENOG4107XDY Nicotinamide Mononucleotide Transporter GQZ26_24355 ENOG4105E0C molybdate abc transporter GQZ26_24360 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein GQZ26_24365 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family GQZ26_24395 ENOG4105F6E Acyl-transferase GQZ26_24415 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) GQZ26_24425 ENOG4108RE7 deoxyribonuclease GQZ26_24430 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) GQZ26_24455 ENOG4105C5H ABC transporter GQZ26_24465 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein GQZ26_24470 ENOG4105DEF Extracellular solute-binding protein, family 5 GQZ26_24480 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GQZ26_24485 ENOG4105C3U ABC transporter GQZ26_24490 ENOG4108JQ7 (ABC) transporter GQZ26_24495 ENOG410667J hydrolase GQZ26_24525 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase GQZ26_24530 ENOG4105ERH Fumarylacetoacetate hydrolase GQZ26_24540 ENOG4105CUB amino acid GQZ26_24545 ENOG4108SC4 )-transporter GQZ26_24550 ENOG4105CPF Cell wall formation (By similarity) GQZ26_24555 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) GQZ26_24580 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein GQZ26_24585 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) GQZ26_24595 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) GQZ26_24695 ENOG4105K8N protein family UPF0079, ATPase GQZ26_24700 ENOG41072GX Peptidase M22 Glycoprotease GQZ26_24705 ENOG410801F ribosomal-protein-alanine acetyltransferase GQZ26_24715 ENOG4105C5H ABC transporter GQZ26_24730 ENOG4108TYN CAAX amino terminal protease family protein GQZ26_24750 ENOG4105C7N Xanthine uracil vitamin C permease GQZ26_24760 ENOG4105BZU Histidine kinase GQZ26_24785 ENOG4107ZXU DSBA oxidoreductase GQZ26_24815 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) GQZ26_24835 ENOG4108SHN Glycosyl transferase, family 2 GQZ26_24855 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family GQZ26_24885 ENOG4105SX7 Transporter GQZ26_24915 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) GQZ26_24920 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit GQZ26_24925 ENOG4105C83 adenylosuccinate lyase GQZ26_24935 ENOG4105VR9 phosphoribosylformylglycinamidine synthase GQZ26_24960 ENOG4108V3E phosphoribosylglycinamide formyltransferase GQZ26_24970 ENOG4105C12 Phosphoribosylglycinamide synthetase GQZ26_24995 ENOG4105C4R Atp-dependent dna helicase GQZ26_25020 ENOG4108W2Y isochorismatase GQZ26_25030 ENOG4108UMI ABC transporter, permease GQZ26_25035 ENOG4105D01 (LipO)protein GQZ26_25055 ENOG410834F Transcriptional regulator GQZ26_25060 ENOG4107I77 yiaA/B two helix domain GQZ26_25080 ENOG4105CBD Diacylglycerol kinase GQZ26_25090 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) GQZ26_25095 ENOG4108JPW Aminotransferase GQZ26_25105 ENOG4105C26 Dehydrogenase GQZ26_25110 ENOG4105KPY Small multidrug resistance protein GQZ26_25125 ENOG4105D9N nucleoside GQZ26_25130 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) GQZ26_25140 ENOG4105BZU Histidine kinase GQZ26_25145 ENOG4105C7K acetolactate synthase GQZ26_25155 ENOG4108W15 Protein of unknown function (DUF1456) GQZ26_25180 ENOG4105DDC Oxidoreductase domain protein GQZ26_25185 ENOG4105CQB FAD linked oxidase domain protein GQZ26_25195 ENOG4105CWC Acetylornithine deacetylase GQZ26_25215 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) GQZ26_25220 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen GQZ26_25230 ENOG4107Y80 Major Facilitator superfamily GQZ26_25240 ENOG4108W15 Protein of unknown function (DUF1456) GQZ26_25255 ENOG4105DTQ mandelate racemase muconate lactonizing GQZ26_25265 ENOG4105DFD Na H antiporter GQZ26_25285 ENOG4105D3R alkyl hydroperoxide reductase GQZ26_25290 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) GQZ26_25300 ENOG4107W7X Aldolase GQZ26_25315 ENOG4105EHG Permease protein GQZ26_25320 ENOG4105DQ5 transport system permease protein GQZ26_25325 ENOG4108V5C ABC transporter GQZ26_25345 ENOG4106UIA GQZ26_25350 ENOG4106UIA GQZ26_25385 ENOG4105D2S major facilitator superfamily GQZ26_25410 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase GQZ26_25415 ENOG4105E5Q amino acid AbC transporter GQZ26_25420 ENOG4105EAB amino acid AbC transporter GQZ26_25430 ENOG4105C8Q Methyl-accepting chemotaxis GQZ26_25440 ENOG4105CI1 PTS System GQZ26_25465 ENOG4107RBB ABC transporter, permease GQZ26_25470 ENOG4105C19 ABC transporter GQZ26_25495 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) GQZ26_25525 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter GQZ26_25540 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component GQZ26_25560 ENOG4105C5H ABC transporter GQZ26_25590 ENOG41062JF Transcriptional regulator GQZ26_25610 ENOG4105DEU major facilitator superfamily GQZ26_25640 ENOG4108N0M stress protein GQZ26_25645 ENOG4106FN3 tellurium resistance protein GQZ26_25650 ENOG4106FN3 tellurium resistance protein GQZ26_25655 ENOG4107TS3 membrane protein, TerC GQZ26_25660 ENOG4108TTB tellurium resistance protein GQZ26_25680 ENOG4105KJF protein tyrosine phosphatase GQZ26_25690 ENOG4107U9T Pfam:Ribonuclease_BN GQZ26_25695 ENOG4105C59 p-type ATPase GQZ26_25715 ENOG4105C3F Signal peptidase i GQZ26_25725 ENOG4107ZTW SNARE associated Golgi GQZ26_25740 ENOG410606W general stress protein GQZ26_25745 ENOG4105UPD Calcium Proton GQZ26_25795 ENOG4108JUB Transcriptional regulator GQZ26_25805 ENOG4108IQI permease GQZ26_25835 ENOG4105CSV Glutaminase GQZ26_25845 ENOG4108A04 Beta-lactamase GQZ26_25860 ENOG4105CKK Glycosyl transferase, family 2 GQZ26_25870 ENOG4105C3I Nad-dependent epimerase dehydratase GQZ26_25890 ENOG4105F1A Pyruvate formate-lyase GQZ26_25915 ENOG4105ECP epimerase GQZ26_25945 ENOG41067AE Membrane-bound metal-dependent hydrolase GQZ26_25950 ENOG4105CEN a g-specific adenine glycosylase GQZ26_25955 ENOG4106BXE GQZ26_25975 ENOG4105BZ1 (ABC) transporter GQZ26_25980 ENOG4107NBY Membrane GQZ26_25985 ENOG4105CBC glutamate synthase GQZ26_25995 ENOG4108IUW ABC transporter GQZ26_26015 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen GQZ26_26020 ENOG4105G5W regulator Fur family GQZ26_26130 ENOG4108JQC penicillin-binding protein 1A GQZ26_26135 ENOG4108R9S DSBA oxidoreductase GQZ26_26150 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) GQZ26_26160 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) GQZ26_26170 ENOG4105CYN Serine protein kinase GQZ26_26190 ENOG4105C94 Transporter GQZ26_26205 ENOG4105DZ6 Band 7 protein GQZ26_26215 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism GQZ26_26220 ENOG4108V9W transcriptional regulatory protein GQZ26_26225 ENOG4105D4T Citrate transporter GQZ26_26250 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator GQZ26_26255 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GQZ26_26260 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component GQZ26_26265 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component GQZ26_26270 ENOG4105BZ7 extracellular solute-binding protein family 1 GQZ26_26275 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) GQZ26_26280 ENOG4108STX response regulator GQZ26_26285 ENOG4105US7 Histidine kinase GQZ26_26305 ENOG4108UZ3 Transporter GQZ26_26310 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family GQZ26_26320 ENOG4105BZU Histidine kinase GQZ26_26325 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GQZ26_26330 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) GQZ26_26335 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) GQZ26_26340 ENOG4108JB9 formate dehydrogenase GQZ26_26360 ENOG4105CUB amino acid GQZ26_26370 ENOG4105C59 p-type ATPase GQZ26_26375 ENOG4105DAP Nicotinate phosphoribosyltransferase GQZ26_26410 ENOG41073R8 VanW family GQZ26_26415 ENOG4108KGH TRANSCRIPTIONal GQZ26_26420 ENOG4105D9N nucleoside GQZ26_26425 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase GQZ26_26430 ENOG4105C37 (CBS) domain GQZ26_26435 ENOG4108IJ0 Aspartate ammonia-lyase GQZ26_26440 ENOG4105DAA L-lactate GQZ26_26455 ENOG4105DUX Transporter GQZ26_26460 ENOG4108MES Periplasmic binding protein GQZ26_26465 ENOG4105DQ5 transport system permease protein GQZ26_26470 ENOG4108IHU transport system permease protein GQZ26_26475 ENOG4105E0A ABC, transporter GQZ26_26480 ENOG4105DMQ Methyltransferase GQZ26_26490 ENOG4105EXW epimerase dehydratase GQZ26_26495 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) GQZ26_26505 ENOG4107T89 von Willebrand factor, type A GQZ26_26510 ENOG4105GMT ATPase associated with various cellular activities aaa_5 GQZ26_26515 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) GQZ26_26530 ENOG4105BZU Histidine kinase GQZ26_26535 ENOG4105D5Q Arginine ornithine antiporter GQZ26_26540 ENOG4107414 GntR family transcriptional regulator GQZ26_26545 ENOG4105C5Y PTS System GQZ26_26550 ENOG4105CG3 alpha amylase, catalytic region GQZ26_26565 ENOG4105E1K spore germination protein GQZ26_26570 ENOG4105CRN Aminoglycoside phosphotransferase GQZ26_26575 ENOG4105BZG amino acid carrier protein GQZ26_26580 ENOG4105CDA abc transporter atp-binding protein GQZ26_26585 ENOG4105CT1 (ABC) transporter GQZ26_26590 ENOG4105EAD ABC transporter GQZ26_26595 ENOG4105DRP amino acid AbC transporter GQZ26_26600 ENOG4108IQI permease GQZ26_26615 ENOG4105GFR rna polymerase sigma factor GQZ26_26625 ENOG4105D29 Helix-turn-helix type 11 domain protein GQZ26_26630 ENOG4105NAE bifunctional deaminase-reductase domain protein GQZ26_26635 ENOG4105BZU Histidine kinase GQZ26_26650 ENOG4105CHH sulfate transporter GQZ26_26655 ENOG41068KF Universal stress protein GQZ26_26665 ENOG4105DEF Extracellular solute-binding protein, family 5 GQZ26_26675 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GQZ26_26680 ENOG4108JQ7 (ABC) transporter GQZ26_26690 ENOG4105CXY transporter GQZ26_26695 ENOG41067TZ transcriptional regulator, MarR family GQZ26_26700 ENOG4105C0R drug resistance transporter emrb qaca subfamily GQZ26_26705 ENOG4105ETE Transcriptional regulator (LacI family GQZ26_26710 ENOG4108RVA ribokinase GQZ26_26720 ENOG4105C2J ABC transporter GQZ26_26725 ENOG4105CNN ABC, transporter GQZ26_26730 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator GQZ26_26735 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GQZ26_26795 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer GQZ26_26800 ENOG41069ER domain protein GQZ26_26815 ENOG4105E1K spore germination protein GQZ26_26820 ENOG4108B31 Spore germination protein GQZ26_26835 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) GQZ26_26840 ENOG4108QY0 Membrane GQZ26_26855 ENOG4105CZ3 stage V sporulation protein ad GQZ26_26860 ENOG41090VF Stage v sporulation protein ac GQZ26_26890 ENOG4105VMP Transcriptional regulator GQZ26_26905 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) GQZ26_26950 ENOG4105K59 histidine triad (HIT) protein GQZ26_26975 ENOG41086D8 Transcriptional regulator GQZ26_27015 ENOG4108IBT Inherit from COG: transposase GQZ26_27040 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GQZ26_27050 ENOG4105KRN Transcriptional regulator, abrb family GQZ26_27080 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) GQZ26_27120 ENOG4105DHF Membrane GQZ26_27195 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_27335 ENOG4105D7V transposase GQZ26_27365 ENOG4107QZI cell division protein FtsK GQZ26_27375 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_27430 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_27545 ENOG41080HT Transcriptional regulator, arsr family GQZ26_27555 ENOG4105K4H Nlp p60 protein GQZ26_27575 ENOG4107SDU Methyl-accepting chemotaxis GQZ26_27580 ENOG4105C8Q Methyl-accepting chemotaxis GQZ26_27595 ENOG4108M1A Chitin-binding protein GQZ26_27655 ENOG4105CIG ABC transporter GQZ26_27675 ENOG4108FPN Integrase GQZ26_27720 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_27740 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_27765 ENOG4105D7V transposase GQZ26_27895 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GQZ26_27905 ENOG4108W2Y isochorismatase GQZ26_27915 ENOG4108NHD germination protein GQZ26_27930 ENOG4105D9M gamma-glutamylcysteine synthetase GQZ26_27940 ENOG4105C4W S-formylglutathione hydrolase GQZ26_27950 ENOG4105KVH Transcriptional regulator GQZ26_28020 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_28080 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) GQZ26_28095 ENOG4107SDU Methyl-accepting chemotaxis GQZ26_28175 ENOG4105KRN Transcriptional regulator, abrb family GQZ26_28180 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) GQZ26_28280 ENOG4105EKQ RNA-directed DNA polymerase GQZ26_28370 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) GQZ26_28405 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) GQZ26_28495 ENOG4108VB1 regulatoR GQZ26_28500 ENOG4106A7E Transcriptional regulator GQZ26_28680 ENOG4105W5Q DNA repair protein (RadC