locus-tag	class	description
LIS80_00010	COG0592	DNA-directed DNA polymerase activity
LIS80_00015	COG2501	S4 domain
LIS80_00025	COG0187	DNA topoisomerase II activity
LIS80_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LIS80_00065	COG0516	GMP reductase activity
LIS80_00065	COG0517	IMP dehydrogenase activity
LIS80_00070	COG1686	Belongs to the peptidase S11 family
LIS80_00100	COG1428	Deoxynucleoside kinase
LIS80_00105	COG1428	Deoxynucleoside kinase
LIS80_00110	COG1335	isochorismatase
LIS80_00115	COG0590	tRNA wobble adenosine to inosine editing
LIS80_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LIS80_00180	COG1982	Orn Lys Arg decarboxylase major
LIS80_00190	COG0470	DNA polymerase III
LIS80_00195	COG1774	PSP1 C-terminal conserved region
LIS80_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LIS80_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LIS80_00220	COG2002	toxin-antitoxin pair type II binding
LIS80_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LIS80_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LIS80_00230	COG0084	hydrolase, TatD family'
LIS80_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LIS80_00250	COG4466	Protein conserved in bacteria
LIS80_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LIS80_00270	COG0251	oxidation-reduction process
LIS80_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LIS80_00305	COG2002	toxin-antitoxin pair type II binding
LIS80_00310	COG2244	polysaccharide biosynthetic process
LIS80_00315	COG3956	TIGRFAM MazG family protein
LIS80_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LIS80_00340	COG1098	S1 RNA binding domain
LIS80_00355	COG2208	phosphoserine phosphatase activity
LIS80_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LIS80_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LIS80_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LIS80_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LIS80_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
LIS80_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LIS80_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LIS80_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LIS80_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LIS80_00420	COG1396	sequence-specific DNA binding
LIS80_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LIS80_00515	COG3880	PFAM UvrB UvrC protein
LIS80_00525	COG0542	response to heat
LIS80_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LIS80_00540	COG4956	integral membrane protein (PIN domain superfamily)
LIS80_00560	COG1045	serine acetyltransferase
LIS80_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LIS80_00580	COG3688	RNA-binding protein containing a PIN domain
LIS80_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LIS80_00600	COG0250	Participates in transcription elongation, termination and antitermination
LIS80_00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LIS80_00625	COG2813	Specifically methylates the guanine in position
LIS80_00640	COG1358	cellular component organization or biogenesis
LIS80_00710	COG0255	Belongs to the universal ribosomal protein uL29 family
LIS80_00770	COG0201	protein transport
LIS80_00780	COG0024	Methionine aminopeptidase
LIS80_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LIS80_00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LIS80_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LIS80_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
LIS80_00855	COG0489	protein tyrosine kinase activity
LIS80_00865	COG2194	sulfuric ester hydrolase activity
LIS80_00870	COG0726	polysaccharide deacetylase
LIS80_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LIS80_00955	COG4856	YbbR-like protein
LIS80_00975	COG0596	Alpha beta hydrolase
LIS80_00995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LIS80_01030	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_01035	COG2011	ABC-type metal ion transport system permease component
LIS80_01045	COG1464	Belongs to the NlpA lipoprotein family
LIS80_01050	COG0604	alcohol dehydrogenase
LIS80_01060	COG0277	FAD linked oxidase domain protein
LIS80_01065	COG2271	Major facilitator Superfamily
LIS80_01075	COG2814	Major facilitator Superfamily
LIS80_01095	COG0601	transmembrane transport
LIS80_01100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LIS80_01105	COG0444	Belongs to the ABC transporter superfamily
LIS80_01110	COG4608	Belongs to the ABC transporter superfamily
LIS80_01115	COG4166	transmembrane transport
LIS80_01125	COG2207	Transcriptional regulator
LIS80_01135	COG1309	transcriptional regulator
LIS80_01145	COG4166	transmembrane transport
LIS80_01150	COG4166	transmembrane transport
LIS80_01155	COG0656	L-ascorbic acid biosynthetic process
LIS80_01160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LIS80_01175	COG4149	molybdate abc transporter
LIS80_01180	COG0725	ABC transporter, periplasmic molybdate-binding protein
LIS80_01185	COG1910	domain protein
LIS80_01200	COG0697	spore germination
LIS80_01215	COG0204	Acyl-transferase
LIS80_01225	COG1609	Transcriptional regulator
LIS80_01235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_01245	COG0084	hydrolase, TatD family'
LIS80_01250	COG5298	Protein conserved in bacteria
LIS80_01275	COG0488	(ABC) transporter
LIS80_01285	COG0747	negative chemotaxis
LIS80_01290	COG0747	negative chemotaxis
LIS80_01295	COG0601	transmembrane transport
LIS80_01300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LIS80_01305	COG0444	Belongs to the ABC transporter superfamily
LIS80_01310	COG4608	Belongs to the ABC transporter superfamily
LIS80_01315	COG0561	phosphatase activity
LIS80_01345	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LIS80_01350	COG0179	Fumarylacetoacetate (FAA) hydrolase
LIS80_01360	COG0531	amino acid
LIS80_01365	COG2814	Major facilitator Superfamily
LIS80_01375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LIS80_01385	COG4294	response to UV
LIS80_01390	COG0705	Rhomboid family
LIS80_01400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LIS80_01405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LIS80_01410	COG0864	Transcriptional regulator
LIS80_01415	COG2337	Toxic component of a toxin-antitoxin (TA) module
LIS80_01420	COG2183	response to ionizing radiation
LIS80_01515	COG0802	atpase or kinase
LIS80_01520	COG1214	PFAM Peptidase M22, glycoprotease
LIS80_01525	COG0456	acetyltransferase
LIS80_01535	COG0488	(ABC) transporter
LIS80_01550	COG1266	CAAX protease self-immunity
LIS80_01570	COG2252	PERMEase
LIS80_01580	COG5002	protein histidine kinase activity
LIS80_01635	COG2226	methyltransferase
LIS80_01655	COG1215	transferase activity, transferring glycosyl groups
LIS80_01675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_01680	COG0506	proline dehydrogenase activity
LIS80_01705	COG0697	spore germination
LIS80_01735	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LIS80_01740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LIS80_01745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LIS80_01755	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LIS80_01770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LIS80_01780	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LIS80_01790	COG0151	Belongs to the GarS family
LIS80_01815	COG0210	DNA helicase
LIS80_01825	COG4851	CamS sex pheromone cAM373 precursor
LIS80_01845	COG1335	isochorismatase
LIS80_01855	COG2011	ABC-type metal ion transport system permease component
LIS80_01860	COG1464	Belongs to the NlpA lipoprotein family
LIS80_01875	COG0003	Pfam Anion-transporting ATPase
LIS80_01880	COG1846	Transcriptional regulator
LIS80_01885	COG4682	membrane
LIS80_01905	COG1597	lipid kinase activity
LIS80_01910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LIS80_01915	COG0546	phosphoglycolate phosphatase activity
LIS80_01920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LIS80_01930	COG1012	belongs to the aldehyde dehydrogenase family
LIS80_01935	COG2076	Multidrug Resistance protein
LIS80_01940	COG2309	aminopeptidase activity
LIS80_01950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_01960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LIS80_01970	COG0028	Belongs to the TPP enzyme family
LIS80_01980	COG4807	Protein conserved in bacteria
LIS80_02005	COG0673	inositol 2-dehydrogenase activity
LIS80_02010	COG0277	FAD linked oxidase domain protein
LIS80_02020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LIS80_02040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LIS80_02045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LIS80_02055	COG2814	Major facilitator Superfamily
LIS80_02065	COG4807	Protein conserved in bacteria
LIS80_02090	COG1757	Na H antiporter
LIS80_02095	COG1473	amidohydrolase
LIS80_02110	COG0450	alkyl hydroperoxide reductase
LIS80_02140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_02145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_02150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_02165	COG0166	Belongs to the GPI family
LIS80_02205	COG3541	Predicted nucleotidyltransferase
LIS80_02210	COG2814	Major facilitator Superfamily
LIS80_02215	COG0723	plastoquinol--plastocyanin reductase activity
LIS80_02215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIS80_02240	COG0765	amino acid transport
LIS80_02245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIS80_02255	COG0840	transmembrane signaling receptor activity
LIS80_02260	COG0366	Alpha amylase catalytic
LIS80_02265	COG2190	(PTS) system
LIS80_02265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIS80_02265	COG1263	PTS System
LIS80_02285	COG1695	Transcriptional regulator
LIS80_02295	COG0577	efflux transmembrane transporter activity
LIS80_02300	COG1136	(ABC) transporter
LIS80_02325	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LIS80_02355	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LIS80_02370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LIS80_02380	COG1116	anion transmembrane transporter activity
LIS80_02390	COG0488	(ABC) transporter
LIS80_02440	COG2270	Major facilitator Superfamily
LIS80_02470	COG2310	stress, protein
LIS80_02475	COG2310	stress, protein
LIS80_02480	COG2310	stress, protein
LIS80_02485	COG0861	Integral membrane protein TerC family
LIS80_02495	COG3853	Toxic anion resistance protein (TelA)
LIS80_02510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LIS80_02520	COG1295	ribonuclease BN
LIS80_02525	COG2217	Heavy metal translocating P-type atpase
LIS80_02530	COG0697	spore germination
LIS80_02545	COG0681	Belongs to the peptidase S26 family
LIS80_02555	COG0586	Pfam SNARE associated Golgi protein
LIS80_02570	COG3871	stress protein (general stress protein 26)
LIS80_02575	COG0387	Pfam Sodium calcium exchanger
LIS80_02585	COG0535	radical SAM domain protein
LIS80_02605	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LIS80_02635	COG3829	transcription factor binding
LIS80_02645	COG0833	amino acid
LIS80_02650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LIS80_02680	COG1263	PTS System
LIS80_02680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIS80_02685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LIS80_02700	COG0463	Glycosyl transferase, family 2
LIS80_02710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LIS80_02710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIS80_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LIS80_02745	COG0402	S-adenosylhomocysteine deaminase activity
LIS80_02750	COG1090	epimerase
LIS80_02780	COG1988	membrane-bound metal-dependent
LIS80_02785	COG1194	a g-specific adenine glycosylase
LIS80_02810	COG1132	(ABC) transporter
LIS80_02815	COG4129	membrane
LIS80_02820	COG0070	glutamate synthase
LIS80_02820	COG0069	glutamate synthase activity
LIS80_02820	COG0067	glutamate synthase
LIS80_02830	COG4555	ABC transporter
LIS80_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LIS80_02855	COG0735	belongs to the Fur family
LIS80_02965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LIS80_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LIS80_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LIS80_03005	COG2766	serine protein kinase
LIS80_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LIS80_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
LIS80_03040	COG2268	Band 7 protein
LIS80_03050	COG3290	protein histidine kinase activity
LIS80_03055	COG4565	transcriptional regulatory protein
LIS80_03060	COG2851	Citrate transporter
LIS80_03085	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LIS80_03090	COG3842	ATPase activity
LIS80_03095	COG1175	transmembrane transport
LIS80_03100	COG0395	ABC-type sugar transport system, permease component
LIS80_03110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LIS80_03115	COG0745	RESPONSE REGULATOR receiver
LIS80_03120	COG5002	protein histidine kinase activity
LIS80_03130	COG4990	cell redox homeostasis
LIS80_03140	COG3290	protein histidine kinase activity
LIS80_03145	COG4565	transcriptional regulatory protein
LIS80_03150	COG3493	citrate carrier protein
LIS80_03155	COG0281	malic enzyme
LIS80_03165	COG0697	spore germination
LIS80_03170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_03180	COG5002	protein histidine kinase activity
LIS80_03185	COG0745	RESPONSE REGULATOR receiver
LIS80_03190	COG0454	-acetyltransferase
LIS80_03190	COG0456	acetyltransferase
LIS80_03195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LIS80_03200	COG3383	formate dehydrogenase (NAD+) activity
LIS80_03205	COG2427	Protein of unknown function (DUF1641)
LIS80_03220	COG0531	amino acid
LIS80_03225	COG0640	Transcriptional regulator
LIS80_03230	COG2217	Heavy metal translocating P-type atpase
LIS80_03235	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LIS80_03250	COG3227	Zinc metalloprotease (Elastase)
LIS80_03270	COG2720	vancomycin resistance protein
LIS80_03275	COG1316	TRANSCRIPTIONal
LIS80_03280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_03285	COG0346	lactoylglutathione lyase activity
LIS80_03290	COG1253	flavin adenine dinucleotide binding
LIS80_03295	COG1027	Aspartate ammonia-lyase
LIS80_03305	COG1620	l-lactate permease
LIS80_03320	COG3104	oligopeptide transport
LIS80_03325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_03330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_03335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_03345	COG2226	methyltransferase
LIS80_03350	COG0156	8-amino-7-oxononanoate synthase activity
LIS80_03355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIS80_03360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LIS80_03370	COG4548	von Willebrand factor, type A
LIS80_03375	COG0714	Associated with various cellular activities
LIS80_03380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIS80_03400	COG0531	amino acid
LIS80_03405	COG2188	Transcriptional regulator
LIS80_03410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIS80_03410	COG1263	PTS System
LIS80_03415	COG0366	Alpha amylase catalytic
LIS80_03430	COG0697	spore germination
LIS80_03440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LIS80_03445	COG1115	amino acid carrier protein
LIS80_03450	COG1126	abc transporter atp-binding protein
LIS80_03455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIS80_03460	COG0765	amino acid transport
LIS80_03465	COG0765	amino acid transport
LIS80_03470	COG0833	amino acid
LIS80_03495	COG2378	regulation of single-species biofilm formation
LIS80_03500	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LIS80_03505	COG5002	protein histidine kinase activity
LIS80_03520	COG0659	secondary active sulfate transmembrane transporter activity
LIS80_03545	COG0601	transmembrane transport
LIS80_03550	COG4608	Belongs to the ABC transporter superfamily
LIS80_03560	COG2271	Major facilitator Superfamily
LIS80_03565	COG1846	Transcriptional regulator
LIS80_03570	COG0477	Major facilitator Superfamily
LIS80_03575	COG1609	Transcriptional regulator
LIS80_03580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LIS80_03595	COG1172	Belongs to the binding-protein-dependent transport system permease family
LIS80_03600	COG1879	ABC-type sugar transport system periplasmic component
LIS80_03625	COG1063	alcohol dehydrogenase
LIS80_03645	COG3568	Endonuclease Exonuclease Phosphatase
LIS80_03675	COG0840	transmembrane signaling receptor activity
LIS80_03680	COG3584	3D domain protein
LIS80_03680	COG3583	domain protein
LIS80_03685	COG1476	TRANSCRIPTIONal
LIS80_03705	COG3104	oligopeptide transport
LIS80_03710	COG1114	Component of the transport system for branched-chain amino acids
LIS80_03725	COG1113	amino acid transport
LIS80_03730	COG2252	PERMEase
LIS80_03745	COG2153	protein acetylation
LIS80_03755	COG0569	domain protein
LIS80_03755	COG0475	glutathione-regulated potassium exporter activity
LIS80_03770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LIS80_03775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LIS80_03780	COG0833	amino acid
LIS80_03785	COG4990	cell redox homeostasis
LIS80_03800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LIS80_03805	COG0697	spore germination
LIS80_03810	COG0531	amino acid
LIS80_03825	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LIS80_03830	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LIS80_03835	COG1918	ferrous iron import across plasma membrane
LIS80_03835	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LIS80_03840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LIS80_03845	COG0573	inorganic phosphate transmembrane transporter activity
LIS80_03850	COG0581	inorganic phosphate transmembrane transporter activity
LIS80_03855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LIS80_03975	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LIS80_03995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LIS80_04000	COG1116	anion transmembrane transporter activity
LIS80_04005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LIS80_04010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LIS80_04015	COG0352	thiamine-phosphate diphosphorylase activity
LIS80_04020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIS80_04025	COG2104	thiamine diphosphate biosynthetic process
LIS80_04035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LIS80_04040	COG0351	phosphomethylpyrimidine kinase
LIS80_04080	COG2205	protein histidine kinase activity
LIS80_04085	COG2814	Major facilitator Superfamily
LIS80_04090	COG1846	Transcriptional regulator
LIS80_04115	COG1136	(ABC) transporter
LIS80_04125	COG1172	Belongs to the binding-protein-dependent transport system permease family
LIS80_04130	COG1129	ABC transporter
LIS80_04140	COG2252	PERMEase
LIS80_04145	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_04165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIS80_04205	COG0778	Nitroreductase
LIS80_04210	COG2719	SpoVR family
LIS80_04230	COG0446	pyridine nucleotide-disulphide oxidoreductase
LIS80_04235	COG1937	Protein conserved in bacteria
LIS80_04240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LIS80_04240	COG0425	Belongs to the sulfur carrier protein TusA family
LIS80_04245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LIS80_04245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_04250	COG0425	Belongs to the sulfur carrier protein TusA family
LIS80_04255	COG0425	Belongs to the sulfur carrier protein TusA family
LIS80_04260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LIS80_04260	COG0425	Belongs to the sulfur carrier protein TusA family
LIS80_04270	COG2210	Belongs to the sulfur carrier protein TusA family
LIS80_04275	COG0730	response to heat
LIS80_04285	COG1316	TRANSCRIPTIONal
LIS80_04290	COG0604	alcohol dehydrogenase
LIS80_04295	COG1283	sodium-dependent phosphate transmembrane transporter activity
LIS80_04300	COG2814	Major facilitator Superfamily
LIS80_04310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIS80_04310	COG3711	transcriptional antiterminator
LIS80_04315	COG1447	Phosphotransferase system cellobiose-specific component IIA
LIS80_04320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LIS80_04345	COG1388	LysM domain
LIS80_04345	COG3584	3D domain protein
LIS80_04350	COG0577	efflux transmembrane transporter activity
LIS80_04355	COG1136	(ABC) transporter
LIS80_04365	COG5522	Integral membrane protein (intg_mem_TP0381)
LIS80_04380	COG1114	Component of the transport system for branched-chain amino acids
LIS80_04385	COG3546	catalase activity
LIS80_04420	COG0586	Pfam SNARE associated Golgi protein
LIS80_04455	COG0531	amino acid
LIS80_04460	COG0475	glutathione-regulated potassium exporter activity
LIS80_04470	COG1737	Transcriptional regulator
LIS80_04480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIS80_04480	COG1263	PTS System
LIS80_04490	COG2259	Doxx family
LIS80_04495	COG3631	Ketosteroid isomerase-related protein
LIS80_04510	COG1522	sequence-specific DNA binding
LIS80_04525	COG2076	Multidrug Resistance protein
LIS80_04530	COG1309	transcriptional regulator
LIS80_04535	COG2814	Major facilitator Superfamily
LIS80_04540	COG1733	regulation of RNA biosynthetic process
LIS80_04550	COG2249	NAD(P)H dehydrogenase (quinone) activity
LIS80_04555	COG4533	DNA binding
LIS80_04560	COG2211	Major facilitator Superfamily
LIS80_04570	COG0693	protein deglycase activity
LIS80_04575	COG0753	catalase activity
LIS80_04585	COG0531	amino acid
LIS80_04590	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LIS80_04600	COG1012	belongs to the aldehyde dehydrogenase family
LIS80_04605	COG1132	(ABC) transporter
LIS80_04610	COG1132	(ABC) transporter
LIS80_04615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIS80_04620	COG0765	amino acid transport
LIS80_04625	COG1126	abc transporter atp-binding protein
LIS80_04640	COG0189	ligase activity
LIS80_04665	COG4585	Histidine kinase
LIS80_04670	COG2197	response regulator
LIS80_04710	COG0028	Belongs to the TPP enzyme family
LIS80_04715	COG3527	Alpha-acetolactate decarboxylase
LIS80_04725	COG0561	phosphatase activity
LIS80_04730	COG3409	Peptidoglycan-binding domain 1 protein
LIS80_04730	COG5632	N-Acetylmuramoyl-L-alanine amidase
LIS80_04735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LIS80_04755	COG0659	secondary active sulfate transmembrane transporter activity
LIS80_04770	COG0653	protein targeting
LIS80_04775	COG2244	polysaccharide biosynthetic process
LIS80_04805	COG1696	Membrane protein involved in D-alanine export
LIS80_04820	COG1024	Enoyl-CoA hydratase
LIS80_04840	COG1363	Peptidase, m42
LIS80_04885	COG0601	transmembrane transport
LIS80_04890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LIS80_04895	COG0444	Belongs to the ABC transporter superfamily
LIS80_04900	COG4608	Belongs to the ABC transporter superfamily
LIS80_04905	COG0477	Major facilitator Superfamily
LIS80_04910	COG3290	protein histidine kinase activity
LIS80_04915	COG4565	transcriptional regulatory protein
LIS80_04920	COG3181	Tripartite tricarboxylate transporter family receptor
LIS80_04985	COG4978	Transcriptional regulator
LIS80_04985	COG0789	Transcriptional regulator
LIS80_05020	COG0305	Participates in initiation and elongation during chromosome replication
LIS80_05115	COG1183	phosphatidylcholine synthase activity
LIS80_05130	COG2376	Dihydroxyacetone kinase
LIS80_05140	COG2376	Dihydroxyacetone kinase
LIS80_05165	COG3437	response regulator, receiver
LIS80_05165	COG2770	Histidine kinase
LIS80_05255	COG3237	CsbD-like
LIS80_05280	COG1191	sigma factor activity
LIS80_05290	COG2208	phosphoserine phosphatase activity
LIS80_05295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LIS80_05300	COG2198	Histidine kinase
LIS80_05300	COG0784	Response regulator, receiver
LIS80_05300	COG2205	protein histidine kinase activity
LIS80_05375	COG0420	3'-5' exonuclease activity
LIS80_05380	COG4717	serine-type aminopeptidase activity
LIS80_05390	COG1309	transcriptional regulator
LIS80_05395	COG2814	Major facilitator Superfamily
LIS80_05400	COG0346	lactoylglutathione lyase activity
LIS80_05405	COG0346	lactoylglutathione lyase activity
LIS80_05415	COG2267	carboxylic ester hydrolase activity
LIS80_05445	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LIS80_05450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LIS80_05460	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LIS80_05475	COG1595	DNA-templated transcription, initiation
LIS80_05485	COG0772	Belongs to the SEDS family
LIS80_05515	COG3973	AAA domain
LIS80_05520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LIS80_05540	COG4980	gas vesicle protein
LIS80_05545	COG0537	adenosine 5'-monophosphoramidase activity
LIS80_05550	COG1131	(ABC) transporter
LIS80_05555	COG4473	ABC transporter
LIS80_05570	COG1309	transcriptional regulator
LIS80_05580	COG3402	PFAM membrane-flanked domain
LIS80_05585	COG3428	Bacterial PH domain
LIS80_05615	COG3402	PFAM membrane-flanked domain
LIS80_05620	COG3428	Bacterial PH domain
LIS80_05625	COG2329	Antibiotic biosynthesis monooxygenase
LIS80_05630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIS80_05645	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LIS80_05675	COG1309	transcriptional regulator
LIS80_05680	COG1511	domain protein
LIS80_05710	COG2378	regulation of single-species biofilm formation
LIS80_05715	COG1609	Transcriptional regulator
LIS80_05725	COG1234	tRNA 3'-trailer cleavage
LIS80_05730	COG0095	Lipoate-protein ligase
LIS80_05740	COG0318	PFAM AMP-dependent synthetase and ligase
LIS80_05820	COG1073	alpha beta
LIS80_05825	COG1408	metallophosphoesterase
LIS80_05835	COG1078	dGTPase activity
LIS80_05845	COG1595	DNA-templated transcription, initiation
LIS80_05850	COG2207	Transcriptional regulator
LIS80_05850	COG3708	Transcriptional regulator
LIS80_05865	COG2205	protein histidine kinase activity
LIS80_05870	COG0745	RESPONSE REGULATOR receiver
LIS80_05895	COG0501	Belongs to the peptidase M48B family
LIS80_05900	COG0697	spore germination
LIS80_05920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LIS80_05925	COG2224	Isocitrate lyase
LIS80_05935	COG1278	Cold shock
LIS80_05950	COG4903	ComK protein
LIS80_05960	COG0398	Pfam SNARE associated Golgi protein
LIS80_06020	COG0179	Fumarylacetoacetate (FAA) hydrolase
LIS80_06045	COG0367	asparagine synthase
LIS80_06050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LIS80_06055	COG0753	catalase activity
LIS80_06060	COG0004	ammonium transporteR
LIS80_06080	COG2996	Protein conserved in bacteria
LIS80_06085	COG3209	COG3209 Rhs family protein
LIS80_06110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LIS80_06120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_06135	COG0561	phosphatase activity
LIS80_06160	COG2267	carboxylic ester hydrolase activity
LIS80_06175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIS80_06180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LIS80_06185	COG5504	Zn-dependent protease
LIS80_06195	COG0180	Tryptophanyl-tRNA synthetase
LIS80_06205	COG4166	transmembrane transport
LIS80_06210	COG0601	transmembrane transport
LIS80_06215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LIS80_06220	COG0444	Belongs to the ABC transporter superfamily
LIS80_06225	COG4608	Belongs to the ABC transporter superfamily
LIS80_06230	COG0534	Mate efflux family protein
LIS80_06235	COG4166	transmembrane transport
LIS80_06250	COG0861	Integral membrane protein TerC family
LIS80_06255	COG4862	establishment of competence for transformation
LIS80_06260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIS80_06270	COG1164	Oligoendopeptidase f
LIS80_06285	COG2346	COG2346, Truncated hemoglobins
LIS80_06290	COG4116	CYTH
LIS80_06300	COG2357	RelA SpoT domain protein
LIS80_06310	COG0564	pseudouridine synthase activity
LIS80_06325	COG0772	Belongs to the SEDS family
LIS80_06330	COG1216	Glycosyl transferase, family 2
LIS80_06330	COG0463	Glycosyl transferase, family 2
LIS80_06350	COG0463	Glycosyl transferase, family 2
LIS80_06350	COG0457	Tetratricopeptide repeat
LIS80_06370	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LIS80_06385	COG1091	dTDP-4-dehydrorhamnose reductase activity
LIS80_06430	COG2153	protein acetylation
LIS80_06440	COG2382	esterase
LIS80_06455	COG5492	domain, Protein
LIS80_06460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LIS80_06470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LIS80_06470	COG0512	Glutamine amidotransferase of anthranilate synthase
LIS80_06505	COG1620	l-lactate permease
LIS80_06510	COG5634	Uncharacterized conserved protein (DUF2278)
LIS80_06515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIS80_06585	COG0508	dehydrogenase complex catalyzes the overall conversion of
LIS80_06595	COG1476	TRANSCRIPTIONal
LIS80_06695	COG0582	viral genome integration into host DNA
LIS80_06710	COG2226	methyltransferase
LIS80_06720	COG1686	Belongs to the peptidase S11 family
LIS80_06725	COG0681	Belongs to the peptidase S26 family
LIS80_06760	COG1012	belongs to the aldehyde dehydrogenase family
LIS80_06770	COG1176	ABC-type spermidine putrescine transport system, permease component I
LIS80_06775	COG1177	transmembrane transport
LIS80_06780	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LIS80_06790	COG2409	Drug exporters of the RND superfamily
LIS80_06800	COG0564	pseudouridine synthase activity
LIS80_06810	COG2340	Cysteine-rich secretory protein family
LIS80_06815	COG0247	lactate metabolic process
LIS80_06820	COG0277	FAD linked oxidase domain protein
LIS80_06825	COG3835	regulator
LIS80_06835	COG0745	RESPONSE REGULATOR receiver
LIS80_06840	COG5002	protein histidine kinase activity
LIS80_06845	COG2186	Transcriptional regulator
LIS80_06865	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LIS80_06875	COG2116	formate transmembrane transporter activity
LIS80_06880	COG0861	Integral membrane protein TerC family
LIS80_06885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LIS80_06895	COG2030	dehydratase
LIS80_06915	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_06920	COG3243	poly(R)-hydroxyalkanoic acid synthase
LIS80_06930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LIS80_06945	COG1840	ABC-type Fe3 transport system, periplasmic component
LIS80_06950	COG3842	ATPase activity
LIS80_06975	COG1349	DNA-binding transcription factor activity
LIS80_06985	COG0235	Class ii aldolase
LIS80_06995	COG2861	carbohydrate metabolic process
LIS80_07005	COG3852	Histidine kinase
LIS80_07010	COG1846	Transcriptional regulator
LIS80_07020	COG2318	DinB family
LIS80_07030	COG5002	protein histidine kinase activity
LIS80_07040	COG0720	synthase
LIS80_07055	COG4873	Protein conserved in bacteria
LIS80_07085	COG1780	Probably involved in ribonucleotide reductase function
LIS80_07115	COG1725	Transcriptional regulator
LIS80_07120	COG1131	(ABC) transporter
LIS80_07130	COG1131	(ABC) transporter
LIS80_07135	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LIS80_07140	COG1266	CAAX protease self-immunity
LIS80_07150	COG1522	sequence-specific DNA binding
LIS80_07160	COG1335	isochorismatase
LIS80_07170	COG1619	proteins homologs of microcin C7 resistance protein MccF
LIS80_07175	COG2070	2-Nitropropane dioxygenase
LIS80_07180	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LIS80_07190	COG1696	Membrane protein involved in D-alanine export
LIS80_07215	COG0716	FMN binding
LIS80_07230	COG3173	Aminoglycoside phosphotransferase
LIS80_07250	COG0534	Mate efflux family protein
LIS80_07270	COG1846	Transcriptional regulator
LIS80_07280	COG1301	dicarboxylic acid transport
LIS80_07285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LIS80_07290	COG4709	membrane
LIS80_07295	COG3874	Sporulation protein YtfJ
LIS80_07315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LIS80_07320	COG0028	Belongs to the TPP enzyme family
LIS80_07325	COG0440	acetolactate synthase activity
LIS80_07400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LIS80_07415	COG1183	phosphatidylcholine synthase activity
LIS80_07420	COG1368	sulfuric ester hydrolase activity
LIS80_07430	COG0019	diaminopimelate decarboxylase activity
LIS80_07450	COG0529	Catalyzes the synthesis of activated sulfate
LIS80_07455	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LIS80_07475	COG1648	precorrin-2 dehydrogenase activity
LIS80_07480	COG0733	neurotransmitter:sodium symporter activity
LIS80_07505	COG1757	Na H antiporter
LIS80_07520	COG4758	membrane
LIS80_07525	COG4585	Histidine kinase
LIS80_07530	COG2197	response regulator
LIS80_07540	COG1114	Component of the transport system for branched-chain amino acids
LIS80_07550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LIS80_07590	COG0730	response to heat
LIS80_07595	COG0306	phosphate transporter
LIS80_07600	COG1392	Phosphate transport regulator
LIS80_07605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIS80_07620	COG3852	Histidine kinase
LIS80_07625	COG1801	Protein of unknown function DUF72
LIS80_07635	COG0582	viral genome integration into host DNA
LIS80_07640	COG5002	protein histidine kinase activity
LIS80_07655	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LIS80_07655	COG0392	lysyltransferase activity
LIS80_07670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LIS80_07675	COG1686	Belongs to the peptidase S11 family
LIS80_07680	COG2715	membrane protein required for spore maturation
LIS80_07685	COG0700	Nucleoside recognition
LIS80_07690	COG1187	pseudouridine synthase activity
LIS80_07700	COG1333	cytochrome c biogenesis protein
LIS80_07705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LIS80_07710	COG0745	RESPONSE REGULATOR receiver
LIS80_07715	COG5002	protein histidine kinase activity
LIS80_07720	COG2096	Adenosyltransferase
LIS80_07725	COG4942	peptidase
LIS80_07735	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LIS80_07740	COG1141	Ferredoxin
LIS80_07750	COG0514	ATP-dependent DNA helicase (RecQ)
LIS80_07755	COG1266	CAAX protease self-immunity
LIS80_07765	COG1408	metallophosphoesterase
LIS80_07775	COG4862	establishment of competence for transformation
LIS80_07780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LIS80_07800	COG0492	ferredoxin-NADP+ reductase activity
LIS80_07880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LIS80_07895	COG0142	geranyltranstransferase activity
LIS80_07905	COG0142	geranyltranstransferase activity
LIS80_07925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LIS80_07935	COG0457	Tetratricopeptide repeat
LIS80_07955	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LIS80_07960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LIS80_07960	COG2010	Cytochrome c
LIS80_07965	COG4347	Protein of unknown function (DUF1405)
LIS80_07980	COG2738	Putative neutral zinc metallopeptidase
LIS80_07990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_07995	COG1694	Mazg nucleotide pyrophosphohydrolase
LIS80_08010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LIS80_08015	COG0438	transferase activity, transferring glycosyl groups
LIS80_08050	COG1199	ATP-dependent helicase activity
LIS80_08050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LIS80_08070	COG3935	DnaD domain protein
LIS80_08075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LIS80_08085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIS80_08085	COG4499	WXG100 protein secretion system (Wss), protein YukC
LIS80_08145	COG0116	Belongs to the methyltransferase superfamily
LIS80_08155	COG1199	ATP-dependent helicase activity
LIS80_08160	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LIS80_08170	COG0024	Methionine aminopeptidase
LIS80_08180	COG2233	PERMEase
LIS80_08185	COG2311	Membrane
LIS80_08190	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LIS80_08200	COG0456	acetyltransferase
LIS80_08235	COG0754	glutathionylspermidine amidase activity
LIS80_08250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LIS80_08270	COG0454	-acetyltransferase
LIS80_08290	COG0328	RNA-DNA hybrid ribonuclease activity
LIS80_08325	COG3403	YqcI/YcgG family
LIS80_08330	COG1280	lysine exporter protein (LysE YggA)
LIS80_08345	COG3162	membrane
LIS80_08350	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LIS80_08355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LIS80_08365	COG0475	glutathione-regulated potassium exporter activity
LIS80_08370	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LIS80_08375	COG0789	Transcriptional regulator
LIS80_08375	COG4978	Transcriptional regulator
LIS80_08385	COG2323	membrane
LIS80_08390	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LIS80_08425	COG2814	Major facilitator Superfamily
LIS80_08455	COG1923	regulation of RNA biosynthetic process
LIS80_08465	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LIS80_08470	COG1360	Flagellar Motor Protein
LIS80_08475	COG2201	protein-glutamate methylesterase activity
LIS80_08480	COG2198	Histidine kinase
LIS80_08480	COG0643	Histidine kinase
LIS80_08485	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LIS80_08485	COG1776	CheC inhibitor of MCP methylation
LIS80_08500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LIS80_08520	COG1256	bacterial-type flagellum assembly
LIS80_08525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LIS80_08545	COG1815	bacterial-type flagellum-dependent cell motility
LIS80_08550	COG1558	bacterial-type flagellum-dependent cell motility
LIS80_08560	COG1766	The M ring may be actively involved in energy transduction
LIS80_08565	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LIS80_08575	COG1157	protein secretion by the type III secretion system
LIS80_08595	COG1749	Flagellar hook protein flgE
LIS80_08610	COG0835	chemotaxis
LIS80_08610	COG0784	Response regulator, receiver
LIS80_08620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LIS80_08630	COG0741	lytic transglycosylase activity
LIS80_08640	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LIS80_08645	COG1776	CheC inhibitor of MCP methylation
LIS80_08645	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LIS80_08655	COG1338	Plays a role in the flagellum-specific transport system
LIS80_08660	COG1987	bacterial-type flagellum assembly
LIS80_08670	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LIS80_08675	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LIS80_08680	COG1419	protein localization to endoplasmic reticulum
LIS80_08685	COG4786	Flagellar basal body rod
LIS80_08710	COG1309	transcriptional regulator
LIS80_08730	COG2329	Antibiotic biosynthesis monooxygenase
LIS80_08745	COG3764	Sortase (surface protein transpeptidase)
LIS80_08750	COG3764	Sortase (surface protein transpeptidase)
LIS80_08775	COG0583	DNA-binding transcription factor activity
LIS80_08780	COG3842	ATPase activity
LIS80_08785	COG0725	ABC transporter, periplasmic molybdate-binding protein
LIS80_08795	COG1234	tRNA 3'-trailer cleavage
LIS80_08825	COG1686	Belongs to the peptidase S11 family
LIS80_08835	COG0406	alpha-ribazole phosphatase activity
LIS80_08855	COG1846	Transcriptional regulator
LIS80_08865	COG0367	asparagine synthase
LIS80_08895	COG1802	Transcriptional regulator
LIS80_08900	COG0697	spore germination
LIS80_08905	COG1216	Glycosyl transferase, family 2
LIS80_08905	COG0438	transferase activity, transferring glycosyl groups
LIS80_08910	COG1757	Na H antiporter
LIS80_08920	COG0114	fumarate hydratase activity
LIS80_08945	COG0534	Mate efflux family protein
LIS80_08950	COG3340	Belongs to the peptidase S51 family
LIS80_08990	COG2733	membrane
LIS80_09025	COG1131	(ABC) transporter
LIS80_09040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIS80_09045	COG4585	Histidine kinase
LIS80_09050	COG2197	response regulator
LIS80_09065	COG0528	UMP kinase activity
LIS80_09075	COG1027	Aspartate ammonia-lyase
LIS80_09080	COG0281	malic enzyme
LIS80_09085	COG4191	Histidine kinase
LIS80_09090	COG0784	Response regulator, receiver
LIS80_09095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LIS80_09115	COG3620	sequence-specific DNA binding
LIS80_09145	COG1051	belongs to the nudix hydrolase family
LIS80_09150	COG0860	N-Acetylmuramoyl-L-alanine amidase
LIS80_09160	COG2814	Major facilitator Superfamily
LIS80_09180	COG1966	Carbon starvation protein
LIS80_09190	COG1695	Transcriptional regulator
LIS80_09200	COG0477	Major facilitator Superfamily
LIS80_09205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIS80_09215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LIS80_09220	COG4166	transmembrane transport
LIS80_09225	COG2223	nitrite transmembrane transporter activity
LIS80_09230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LIS80_09245	COG2244	polysaccharide biosynthetic process
LIS80_09250	COG0733	neurotransmitter:sodium symporter activity
LIS80_09260	COG5566	PFAM Mor transcription activator
LIS80_09265	COG2323	membrane
LIS80_09280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LIS80_09285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LIS80_09290	COG0028	Belongs to the TPP enzyme family
LIS80_09295	COG0440	acetolactate synthase activity
LIS80_09310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LIS80_09335	COG2814	Major facilitator Superfamily
LIS80_09340	COG3384	dioxygenase
LIS80_09350	COG3279	Response regulator of the LytR AlgR family
LIS80_09355	COG0427	acetyl-CoA hydrolase
LIS80_09375	COG1073	alpha beta
LIS80_09380	COG4166	transmembrane transport
LIS80_09385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_09390	COG0745	RESPONSE REGULATOR receiver
LIS80_09405	COG1914	H( )-stimulated, divalent metal cation uptake system
LIS80_09420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LIS80_09425	COG0531	amino acid
LIS80_09445	COG0457	Tetratricopeptide repeat
LIS80_09455	COG2390	Transcriptional regulator
LIS80_09465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_09470	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LIS80_09480	COG4846	Membrane protein involved in cytochrome C biogenesis
LIS80_09490	COG0006	proline dipeptidase activity
LIS80_09505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LIS80_09530	COG1114	Component of the transport system for branched-chain amino acids
LIS80_09540	COG2372	response to copper ion
LIS80_09540	COG1276	copper resistance
LIS80_09550	COG0697	spore germination
LIS80_09555	COG0583	DNA-binding transcription factor activity
LIS80_09560	COG1959	2 iron, 2 sulfur cluster binding
LIS80_09565	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LIS80_09570	COG0778	Nitroreductase
LIS80_09580	COG0628	permease
LIS80_09590	COG1231	oxidoreductase activity
LIS80_09595	COG0523	cobalamin synthesis protein
LIS80_09605	COG0411	ABC transporter
LIS80_09635	COG1942	4-Oxalocrotonate Tautomerase
LIS80_09655	COG1271	oxidase subunit
LIS80_09660	COG1294	oxidase, subunit
LIS80_09665	COG4988	ABC transporter
LIS80_09670	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LIS80_09680	COG1216	Glycosyl transferase, family 2
LIS80_09720	COG1686	Belongs to the peptidase S11 family
LIS80_09735	COG0791	NLP P60 protein
LIS80_09735	COG1388	LysM domain
LIS80_09745	COG1132	(ABC) transporter
LIS80_09750	COG0745	RESPONSE REGULATOR receiver
LIS80_09755	COG5002	protein histidine kinase activity
LIS80_09765	COG0300	oxidoreductase activity
LIS80_09770	COG4122	O-methyltransferase activity
LIS80_09800	COG0460	homoserine dehydrogenase
LIS80_09825	COG1316	TRANSCRIPTIONal
LIS80_09845	COG1285	pathogenesis
LIS80_09850	COG1247	-acetyltransferase
LIS80_09860	COG2814	Major facilitator Superfamily
LIS80_09865	COG1279	arginine transmembrane transporter activity
LIS80_09870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_09880	COG1752	Esterase of the alpha-beta hydrolase superfamily
LIS80_09915	COG0577	efflux transmembrane transporter activity
LIS80_09920	COG2002	toxin-antitoxin pair type II binding
LIS80_09925	COG1404	Belongs to the peptidase S8 family
LIS80_09930	COG3842	ATPase activity
LIS80_09935	COG2508	Transcriptional regulator
LIS80_09945	COG1653	transport
LIS80_09950	COG1175	transmembrane transport
LIS80_09955	COG0395	ABC-type sugar transport system, permease component
LIS80_09960	COG5426	von Willebrand factor, type A
LIS80_09970	COG1940	carbohydrate kinase activity
LIS80_09975	COG2222	sugar isomerase
LIS80_09985	COG1105	Belongs to the carbohydrate kinase PfkB family
LIS80_09990	COG3684	Belongs to the aldolase LacD family
LIS80_09995	COG0366	Alpha amylase catalytic
LIS80_10000	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LIS80_10005	COG0640	Transcriptional regulator
LIS80_10010	COG0667	Aldo Keto reductase
LIS80_10015	COG2814	Major facilitator Superfamily
LIS80_10040	COG0840	transmembrane signaling receptor activity
LIS80_10055	COG3949	Membrane
LIS80_10060	COG0783	Belongs to the Dps family
LIS80_10075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LIS80_10085	COG1231	oxidoreductase activity
LIS80_10090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_10095	COG4989	oxidoreductase activity
LIS80_10100	COG0523	cobalamin synthesis protein
LIS80_10105	COG0456	acetyltransferase
LIS80_10110	COG0803	Belongs to the bacterial solute-binding protein 9 family
LIS80_10110	COG3443	Belongs to the bacterial solute-binding protein 9 family
LIS80_10120	COG0702	epimerase
LIS80_10130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LIS80_10140	COG4166	transmembrane transport
LIS80_10155	COG0406	alpha-ribazole phosphatase activity
LIS80_10165	COG5337	Spore coat protein CotH
LIS80_10170	COG1051	belongs to the nudix hydrolase family
LIS80_10175	COG0586	Pfam SNARE associated Golgi protein
LIS80_10180	COG2244	polysaccharide biosynthetic process
LIS80_10190	COG0701	Predicted permease
LIS80_10195	COG3689	TIGRFAM TIGR03943 family protein
LIS80_10200	COG1607	acyl-coa hydrolase
LIS80_10210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIS80_10225	COG0702	epimerase
LIS80_10230	COG2839	Protein conserved in bacteria
LIS80_10235	COG1253	flavin adenine dinucleotide binding
LIS80_10255	COG1114	Component of the transport system for branched-chain amino acids
LIS80_10260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LIS80_10280	COG0860	N-Acetylmuramoyl-L-alanine amidase
LIS80_10290	COG1876	peptidase activity
LIS80_10300	COG0154	amidase activity
LIS80_10305	COG2211	Major facilitator Superfamily
LIS80_10325	COG0561	phosphatase activity
LIS80_10335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LIS80_10340	COG4106	trans-aconitate 2-methyltransferase activity
LIS80_10355	COG1819	glycosyl
LIS80_10360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_10365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_10395	COG0456	acetyltransferase
LIS80_10420	COG3874	Sporulation protein YtfJ
LIS80_10445	COG2226	methyltransferase
LIS80_10470	COG0582	viral genome integration into host DNA
LIS80_10480	COG3620	sequence-specific DNA binding
LIS80_10535	COG1191	sigma factor activity
LIS80_10560	COG0756	dUTP diphosphatase activity
LIS80_10605	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LIS80_10610	COG0582	viral genome integration into host DNA
LIS80_10645	COG1802	Transcriptional regulator
LIS80_10645	COG4626	Terminase
LIS80_10655	COG0740	serine-type endopeptidase activity
LIS80_10735	COG4824	toxin secretion phage lysis holin
LIS80_10790	COG0604	alcohol dehydrogenase
LIS80_10795	COG1595	DNA-templated transcription, initiation
LIS80_10810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LIS80_10810	COG0426	domain, Protein
LIS80_10820	COG0386	Belongs to the glutathione peroxidase family
LIS80_10825	COG1305	Transglutaminase-like
LIS80_10830	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LIS80_10835	COG0714	Associated with various cellular activities
LIS80_10850	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LIS80_10855	COG1140	nitrate reductase beta subunit
LIS80_10860	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LIS80_10865	COG2181	nitrate reductase activity
LIS80_10870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LIS80_10875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LIS80_10880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LIS80_10885	COG0303	'Molybdopterin
LIS80_10890	COG0314	molybdopterin synthase activity
LIS80_10900	COG2223	nitrite transmembrane transporter activity
LIS80_10920	COG1648	precorrin-2 dehydrogenase activity
LIS80_10930	COG1587	Uroporphyrinogen-III synthase
LIS80_10930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LIS80_10935	COG2146	nitrite reductase [NAD(P)H] activity
LIS80_10940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LIS80_10945	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
LIS80_10980	COG2359	stage V sporulation protein S
LIS80_11000	COG1418	mRNA catabolic process
LIS80_11005	COG0488	(ABC) transporter
LIS80_11020	COG0629	single-stranded DNA binding
LIS80_11035	COG1413	lyase activity
LIS80_11050	COG2521	methyltransferase
LIS80_11050	COG2136	Putative SAM-dependent methyltransferase
LIS80_11085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LIS80_11090	COG0017	Asparaginyl-tRNA synthetase
LIS80_11095	COG0733	neurotransmitter:sodium symporter activity
LIS80_11120	COG2610	gluconate transmembrane transporter activity
LIS80_11125	COG1454	alcohol dehydrogenase
LIS80_11130	COG1794	racemase activity, acting on amino acids and derivatives
LIS80_11140	COG0456	acetyltransferase
LIS80_11145	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LIS80_11155	COG1131	(ABC) transporter
LIS80_11160	COG4473	ABC transporter
LIS80_11170	COG0546	phosphoglycolate phosphatase activity
LIS80_11185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LIS80_11190	COG3250	beta-galactosidase activity
LIS80_11205	COG0768	penicillin binding
LIS80_11215	COG0204	Acyl-transferase
LIS80_11220	COG1272	protein, Hemolysin III
LIS80_11230	COG0805	protein transport
LIS80_11240	COG1307	EDD domain protein, DegV family
LIS80_11245	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LIS80_11250	COG1999	signal sequence binding
LIS80_11255	COG0071	Belongs to the small heat shock protein (HSP20) family
LIS80_11260	COG0367	asparagine synthase
LIS80_11275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_11280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LIS80_11295	COG1335	isochorismatase
LIS80_11300	COG1051	belongs to the nudix hydrolase family
LIS80_11310	COG0668	transmembrane transport
LIS80_11315	COG2203	Gaf domain
LIS80_11315	COG4585	Histidine kinase
LIS80_11320	COG2197	response regulator
LIS80_11330	COG1064	alcohol dehydrogenase
LIS80_11390	COG0517	IMP dehydrogenase activity
LIS80_11390	COG1125	glycine betaine transport
LIS80_11395	COG1174	glycine betaine transport
LIS80_11430	COG1253	flavin adenine dinucleotide binding
LIS80_11435	COG1012	belongs to the aldehyde dehydrogenase family
LIS80_11440	COG5506	Protein of unknown function (DUF1694)
LIS80_11455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LIS80_11460	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LIS80_11465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LIS80_11470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LIS80_11475	COG0456	acetyltransferase
LIS80_11480	COG3829	transcription factor binding
LIS80_11485	COG1509	lysine 2,3-aminomutase activity
LIS80_11520	COG0515	serine threonine protein kinase
LIS80_11520	COG3064	Membrane
LIS80_11520	COG4991	sh3 domain protein
LIS80_11525	COG4326	sporulation control protein
LIS80_11530	COG0671	phosphoesterase, PA-phosphatase related
LIS80_11535	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LIS80_11540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIS80_11555	COG5484	DNA packaging
LIS80_11555	COG3728	DNA packaging
LIS80_11590	COG1595	DNA-templated transcription, initiation
LIS80_11620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LIS80_11675	COG4499	WXG100 protein secretion system (Wss), protein YukC
LIS80_11675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIS80_11685	COG2814	Major facilitator Superfamily
LIS80_11695	COG0372	Belongs to the citrate synthase family
LIS80_11700	COG2079	MmgE PrpD family protein
LIS80_11705	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LIS80_11710	COG1960	acyl-CoA dehydrogenase activity
LIS80_11715	COG2084	Dehydrogenase
LIS80_11725	COG1280	lysine exporter protein (LysE YggA)
LIS80_11730	COG1024	Enoyl-CoA hydratase
LIS80_11745	COG0420	3'-5' exonuclease activity
LIS80_11775	COG2223	nitrite transmembrane transporter activity
LIS80_11780	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_11785	COG1169	isochorismate synthase
LIS80_11790	COG1021	2,3-dihydroxybenzoate-AMP ligase
LIS80_11795	COG1535	isochorismatase
LIS80_11795	COG3433	isochorismatase activity
LIS80_11800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LIS80_11805	COG3251	PFAM MbtH domain protein
LIS80_11810	COG2814	Major facilitator Superfamily
LIS80_11825	COG0776	regulation of translation
LIS80_11835	COG2318	DinB family
LIS80_11845	COG1115	amino acid carrier protein
LIS80_11870	COG2329	Antibiotic biosynthesis monooxygenase
LIS80_11875	COG1187	pseudouridine synthase activity
LIS80_11880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LIS80_11885	COG1136	(ABC) transporter
LIS80_11920	COG0028	Belongs to the TPP enzyme family
LIS80_11990	COG1247	-acetyltransferase
LIS80_12015	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LIS80_12020	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LIS80_12030	COG2226	methyltransferase
LIS80_12035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_12045	COG1278	Cold shock
LIS80_12060	COG0010	Belongs to the arginase family
LIS80_12065	COG0561	phosphatase activity
LIS80_12075	COG1846	Transcriptional regulator
LIS80_12080	COG2814	Major facilitator Superfamily
LIS80_12085	COG0583	DNA-binding transcription factor activity
LIS80_12090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LIS80_12105	COG0583	DNA-binding transcription factor activity
LIS80_12110	COG2258	MOSC domain
LIS80_12125	COG1132	(ABC) transporter
LIS80_12130	COG1132	(ABC) transporter
LIS80_12150	COG1396	sequence-specific DNA binding
LIS80_12190	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
LIS80_12195	COG1595	DNA-templated transcription, initiation
LIS80_12225	COG1649	PFAM Uncharacterised BCR, COG1649
LIS80_12250	COG2971	BadF BadG BcrA BcrD
LIS80_12260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LIS80_12315	COG1309	transcriptional regulator
LIS80_12330	COG0577	efflux transmembrane transporter activity
LIS80_12330	COG1136	(ABC) transporter
LIS80_12335	COG0500	methyltransferase
LIS80_12335	COG3615	Tellurite resistance protein tehB
LIS80_12350	COG3961	Belongs to the TPP enzyme family
LIS80_12380	COG2195	Cleaves the N-terminal amino acid of tripeptides
LIS80_12395	COG1595	DNA-templated transcription, initiation
LIS80_12405	COG0768	penicillin binding
LIS80_12410	COG0768	penicillin binding
LIS80_12415	COG2367	Beta-lactamase
LIS80_12420	COG1408	metallophosphoesterase
LIS80_12430	COG1131	(ABC) transporter
LIS80_12440	COG1309	transcriptional regulator
LIS80_12455	COG1960	acyl-CoA dehydrogenase activity
LIS80_12460	COG0439	Biotin carboxylase
LIS80_12465	COG0511	ligase activity, forming carbon-carbon bonds
LIS80_12470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LIS80_12475	COG1024	Enoyl-CoA hydratase
LIS80_12480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LIS80_12485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LIS80_12500	COG0572	uridine kinase
LIS80_12510	COG2318	DinB family
LIS80_12515	COG1686	Belongs to the peptidase S11 family
LIS80_12540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LIS80_12565	COG3227	Zinc metalloprotease (Elastase)
LIS80_12615	COG2226	methyltransferase
LIS80_12645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_12660	COG1063	alcohol dehydrogenase
LIS80_12670	COG2323	membrane
LIS80_12675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LIS80_12685	COG3386	PFAM SMP-30 Gluconolaconase
LIS80_12695	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LIS80_12700	COG3773	Cell wall hydrolase
LIS80_12710	COG0745	RESPONSE REGULATOR receiver
LIS80_12715	COG2205	protein histidine kinase activity
LIS80_12725	COG0488	(ABC) transporter
LIS80_12730	COG1136	(ABC) transporter
LIS80_12735	COG0577	efflux transmembrane transporter activity
LIS80_12755	COG0460	homoserine dehydrogenase
LIS80_12760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_12770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LIS80_12820	COG2124	cytochrome p450
LIS80_12850	COG0561	phosphatase activity
LIS80_12885	COG5002	protein histidine kinase activity
LIS80_12890	COG0768	penicillin binding
LIS80_12900	COG1794	racemase activity, acting on amino acids and derivatives
LIS80_12925	COG2205	protein histidine kinase activity
LIS80_12935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LIS80_12940	COG0604	alcohol dehydrogenase
LIS80_12945	COG0671	phosphoesterase, PA-phosphatase related
LIS80_12950	COG0768	penicillin binding
LIS80_12960	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_13015	COG0584	glycerophosphoryl diester phosphodiesterase
LIS80_13030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_13035	COG0697	spore germination
LIS80_13045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LIS80_13060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LIS80_13070	COG2223	nitrite transmembrane transporter activity
LIS80_13085	COG2816	NAD+ diphosphatase activity
LIS80_13090	COG0592	DNA-directed DNA polymerase activity
LIS80_13095	COG1051	belongs to the nudix hydrolase family
LIS80_13125	COG3878	Protein conserved in bacteria
LIS80_13150	COG4667	esterase of the alpha-beta hydrolase superfamily
LIS80_13190	COG0322	excinuclease ABC activity
LIS80_13230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIS80_13255	COG1011	Hydrolase
LIS80_13275	COG1523	belongs to the glycosyl hydrolase 13 family
LIS80_13280	COG3227	Zinc metalloprotease (Elastase)
LIS80_13300	COG0201	protein transport
LIS80_13345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_13360	COG2959	enzyme of heme biosynthesis
LIS80_13395	COG1309	transcriptional regulator
LIS80_13425	COG3284	Transcriptional regulator
LIS80_13445	COG1349	DNA-binding transcription factor activity
LIS80_13460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LIS80_13465	COG0508	dehydrogenase complex catalyzes the overall conversion of
LIS80_13470	COG0022	dehydrogenase e1 component
LIS80_13475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LIS80_13485	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_13490	COG0456	acetyltransferase
LIS80_13490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LIS80_13505	COG0494	nUDIX hydrolase
LIS80_13530	COG4176	ABC-type proline glycine betaine transport system permease component
LIS80_13535	COG0517	IMP dehydrogenase activity
LIS80_13535	COG4175	Glycine betaine
LIS80_13565	COG2153	protein acetylation
LIS80_13570	COG1819	glycosyl
LIS80_13590	COG2205	protein histidine kinase activity
LIS80_13595	COG2226	methyltransferase
LIS80_13600	COG2315	Protein conserved in bacteria
LIS80_13615	COG3344	reverse transcriptase
LIS80_13660	COG3973	AAA domain
LIS80_13680	COG0514	ATP-dependent DNA helicase (RecQ)
LIS80_13710	COG4637	Psort location Cytoplasmic, score
LIS80_13730	COG3397	chitin binding
LIS80_13745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LIS80_13750	COG1115	amino acid carrier protein
LIS80_13755	COG1012	belongs to the aldehyde dehydrogenase family
LIS80_13760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LIS80_13770	COG3938	Belongs to the proline racemase family
LIS80_13775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIS80_13815	COG0586	Pfam SNARE associated Golgi protein
LIS80_13820	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LIS80_13825	COG0519	Catalyzes the synthesis of GMP from XMP
LIS80_13830	COG4166	transmembrane transport
LIS80_13840	COG4948	Mandelate Racemase Muconate Lactonizing
LIS80_13890	COG2936	dipeptidyl-peptidase activity
LIS80_13900	COG0745	RESPONSE REGULATOR receiver
LIS80_13935	COG1164	Oligoendopeptidase f
LIS80_13945	COG1307	EDD domain protein, DegV family
LIS80_13985	COG2814	Major facilitator Superfamily
LIS80_13995	COG1664	Polymer-forming cytoskeletal
LIS80_14000	COG0789	Transcriptional regulator
LIS80_14005	COG4533	DNA binding
LIS80_14010	COG0477	Major facilitator Superfamily
LIS80_14010	COG2814	Major facilitator Superfamily
LIS80_14035	COG2261	transglycosylase associated protein
LIS80_14050	COG2226	methyltransferase
LIS80_14080	COG0436	Aminotransferase
LIS80_14085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LIS80_14090	COG5146	pantothenate kinase activity
LIS80_14095	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LIS80_14150	COG0628	permease
LIS80_14165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LIS80_14170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LIS80_14175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LIS80_14220	COG2746	aminoglycoside 3-N-acetyltransferase activity
LIS80_14240	COG0697	spore germination
LIS80_14245	COG2318	DinB family
LIS80_14290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIS80_14305	COG0861	Integral membrane protein TerC family
LIS80_14310	COG1368	sulfuric ester hydrolase activity
LIS80_14315	COG0488	(ABC) transporter
LIS80_14325	COG1033	growth of symbiont in host cell
LIS80_14325	COG2409	Drug exporters of the RND superfamily
LIS80_14330	COG1309	transcriptional regulator
LIS80_14345	COG0287	Prephenate dehydrogenase
LIS80_14360	COG1605	Chorismate mutase
LIS80_14360	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LIS80_14390	COG3584	3D domain protein
LIS80_14390	COG1388	LysM domain
LIS80_14415	COG1172	Belongs to the binding-protein-dependent transport system permease family
LIS80_14425	COG2390	Transcriptional regulator
LIS80_14430	COG1070	Carbohydrate kinase
LIS80_14450	COG2329	Antibiotic biosynthesis monooxygenase
LIS80_14465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_14480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LIS80_14485	COG4187	Peptidase family M20/M25/M40
LIS80_14490	COG1414	Transcriptional regulator
LIS80_14495	COG0833	amino acid
LIS80_14500	COG1690	Belongs to the RtcB family
LIS80_14505	COG3239	Fatty acid desaturase
LIS80_14515	COG1785	Belongs to the alkaline phosphatase family
LIS80_14525	COG3655	Transcriptional regulator
LIS80_14540	COG4377	Putative membrane peptidase family (DUF2324)
LIS80_14550	COG3279	Response regulator of the LytR AlgR family
LIS80_14565	COG0346	lactoylglutathione lyase activity
LIS80_14585	COG0714	Associated with various cellular activities
LIS80_14605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LIS80_14610	COG0753	catalase activity
LIS80_14615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LIS80_14635	COG1846	Transcriptional regulator
LIS80_14640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LIS80_14665	COG0714	Associated with various cellular activities
LIS80_14675	COG0778	Nitroreductase
LIS80_14680	COG1846	Transcriptional regulator
LIS80_14715	COG1725	Transcriptional regulator
LIS80_14725	COG1136	(ABC) transporter
LIS80_14750	COG1136	(ABC) transporter
LIS80_14780	COG0456	acetyltransferase
LIS80_14800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_14815	COG0642	Histidine kinase
LIS80_14820	COG0745	RESPONSE REGULATOR receiver
LIS80_14825	COG0596	Alpha beta hydrolase
LIS80_14855	COG0730	response to heat
LIS80_14865	COG0833	amino acid
LIS80_14875	COG4335	DNA alkylation repair
LIS80_14880	COG4978	Transcriptional regulator
LIS80_14880	COG0789	Transcriptional regulator
LIS80_14915	COG0768	penicillin binding
LIS80_14950	COG1984	allophanate hydrolase subunit 2
LIS80_14955	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LIS80_14960	COG1414	Transcriptional regulator
LIS80_14970	COG3142	Participates in the control of copper homeostasis
LIS80_14975	COG0860	N-Acetylmuramoyl-L-alanine amidase
LIS80_14980	COG0640	Transcriptional regulator
LIS80_14990	COG2814	Major facilitator Superfamily
LIS80_15000	COG1960	acyl-CoA dehydrogenase activity
LIS80_15015	COG3314	Sporulation integral membrane protein YlbJ
LIS80_15040	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LIS80_15055	COG0574	Belongs to the PEP-utilizing enzyme family
LIS80_15055	COG3848	Pyruvate phosphate dikinase
LIS80_15065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_15080	COG5577	PFAM Coat F domain
LIS80_15085	COG3403	YqcI/YcgG family
LIS80_15090	COG1280	lysine exporter protein (LysE YggA)
LIS80_15095	COG1113	amino acid transport
LIS80_15125	COG1063	alcohol dehydrogenase
LIS80_15135	COG1027	Aspartate ammonia-lyase
LIS80_15140	COG0252	asparaginase activity
LIS80_15145	COG1396	sequence-specific DNA binding
LIS80_15150	COG2801	Transposase and inactivated derivatives
LIS80_15155	COG0322	excinuclease ABC activity
LIS80_15160	COG0531	amino acid
LIS80_15165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LIS80_15175	COG0531	amino acid
LIS80_15185	COG0784	Response regulator, receiver
LIS80_15190	COG4191	Histidine kinase
LIS80_15195	COG2066	Belongs to the glutaminase family
LIS80_15200	COG1115	amino acid carrier protein
LIS80_15220	COG0723	plastoquinol--plastocyanin reductase activity
LIS80_15220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIS80_15225	COG0534	Mate efflux family protein
LIS80_15235	COG0531	amino acid
LIS80_15240	COG0737	Belongs to the 5'-nucleotidase family
LIS80_15245	COG0753	catalase activity
LIS80_15255	COG0598	Magnesium transport protein CorA
LIS80_15305	COG0415	Belongs to the DNA photolyase family
LIS80_15320	COG0288	reversible hydration of carbon dioxide
LIS80_15330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LIS80_15335	COG5609	conserved protein (DUF2294)
LIS80_15350	COG0697	spore germination
LIS80_15360	COG1575	Belongs to the MenA family. Type 1 subfamily
LIS80_15365	COG4641	Protein conserved in bacteria
LIS80_15370	COG1136	(ABC) transporter
LIS80_15375	COG0577	efflux transmembrane transporter activity
LIS80_15410	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_15410	COG3347	Dehydrogenase
LIS80_15420	COG1070	Carbohydrate kinase
LIS80_15425	COG0235	Class ii aldolase
LIS80_15435	COG1172	Belongs to the binding-protein-dependent transport system permease family
LIS80_15445	COG4154	Belongs to the RbsD FucU family
LIS80_15470	COG0798	PFAM Bile acid sodium symporter
LIS80_15475	COG0346	lactoylglutathione lyase activity
LIS80_15480	COG0640	Transcriptional regulator
LIS80_15490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LIS80_15510	COG1136	(ABC) transporter
LIS80_15550	COG3320	Male sterility
LIS80_15550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LIS80_15555	COG1309	transcriptional regulator
LIS80_15560	COG2814	Major facilitator Superfamily
LIS80_15565	COG1309	transcriptional regulator
LIS80_15570	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_15575	COG1522	sequence-specific DNA binding
LIS80_15590	COG0346	lactoylglutathione lyase activity
LIS80_15625	COG2814	Major facilitator Superfamily
LIS80_15635	COG4895	conserved protein (DUF2196)
LIS80_15685	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LIS80_15705	COG0789	Transcriptional regulator
LIS80_15710	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LIS80_15730	COG0577	efflux transmembrane transporter activity
LIS80_15750	COG5002	protein histidine kinase activity
LIS80_15750	COG3850	Histidine kinase
LIS80_15760	COG2364	Membrane
LIS80_15765	COG1846	Transcriptional regulator
LIS80_15770	COG0456	acetyltransferase
LIS80_15775	COG2808	Putative FMN-binding domain
LIS80_15780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_15785	COG2271	Major facilitator Superfamily
LIS80_15790	COG1556	Lactate utilization protein
LIS80_15795	COG1139	Iron-sulfur cluster binding protein
LIS80_15805	COG0583	DNA-binding transcription factor activity
LIS80_15820	COG1619	proteins homologs of microcin C7 resistance protein MccF
LIS80_15835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LIS80_15855	COG0662	Cupin 2, conserved barrel domain protein
LIS80_15860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_15860	COG2207	Transcriptional regulator
LIS80_15880	COG3409	Peptidoglycan-binding domain 1 protein
LIS80_15880	COG5632	N-Acetylmuramoyl-L-alanine amidase
LIS80_15920	COG0477	Major facilitator Superfamily
LIS80_15935	COG1846	Transcriptional regulator
LIS80_15940	COG2814	Major facilitator Superfamily
LIS80_15950	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LIS80_15955	COG1131	(ABC) transporter
LIS80_15975	COG2076	Multidrug Resistance protein
LIS80_15980	COG1309	transcriptional regulator
LIS80_15990	COG2031	fatty acid transporter
LIS80_16000	COG2249	NAD(P)H dehydrogenase (quinone) activity
LIS80_16035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LIS80_16050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LIS80_16055	COG1288	antiporter activity
LIS80_16080	COG0789	Transcriptional regulator
LIS80_16095	COG3620	sequence-specific DNA binding
LIS80_16100	COG0494	nUDIX hydrolase
LIS80_16115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LIS80_16140	COG1733	regulation of RNA biosynthetic process
LIS80_16145	COG0778	Nitroreductase
LIS80_16165	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_16175	COG1131	(ABC) transporter
LIS80_16200	COG1011	Hydrolase
LIS80_16205	COG2365	Tyrosine phosphatase family
LIS80_16225	COG0346	lactoylglutathione lyase activity
LIS80_16230	COG1940	carbohydrate kinase activity
LIS80_16235	COG0110	maltose O-acetyltransferase activity
LIS80_16250	COG0628	permease
LIS80_16280	COG0500	methyltransferase
LIS80_16290	COG0477	Major facilitator Superfamily
LIS80_16315	COG1253	flavin adenine dinucleotide binding
LIS80_16320	COG0789	Transcriptional regulator
LIS80_16330	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LIS80_16360	COG0697	spore germination
LIS80_16375	COG1357	PFAM Pentapeptide repeats (8 copies)
LIS80_16380	COG3813	Protein conserved in bacteria
LIS80_16385	COG2706	6-phosphogluconolactonase activity
LIS80_16390	COG1070	Carbohydrate kinase
LIS80_16400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LIS80_16405	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LIS80_16415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LIS80_16430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LIS80_16440	COG0604	alcohol dehydrogenase
LIS80_16440	COG3321	synthase
LIS80_16445	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_16460	COG0656	L-ascorbic acid biosynthetic process
LIS80_16465	COG2814	Major facilitator Superfamily
LIS80_16480	COG0346	lactoylglutathione lyase activity
LIS80_16485	COG0814	amino acid
LIS80_16510	COG1393	Belongs to the ArsC family
LIS80_16515	COG1733	regulation of RNA biosynthetic process
LIS80_16520	COG2188	Transcriptional regulator
LIS80_16525	COG0673	inositol 2-dehydrogenase activity
LIS80_16530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LIS80_16535	COG1733	regulation of RNA biosynthetic process
LIS80_16540	COG1733	regulation of RNA biosynthetic process
LIS80_16560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_16580	COG0384	phenazine biosynthesis protein PhzF
LIS80_16590	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_16605	COG0318	PFAM AMP-dependent synthetase and ligase
LIS80_16610	COG2249	NAD(P)H dehydrogenase (quinone) activity
LIS80_16615	COG1733	regulation of RNA biosynthetic process
LIS80_16640	COG1191	sigma factor activity
LIS80_16660	COG1309	transcriptional regulator
LIS80_16705	COG1151	hydroxylamine reductase activity
LIS80_16715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_16750	COG2072	flavoprotein involved in K transport
LIS80_16785	COG0604	alcohol dehydrogenase
LIS80_16790	COG1113	amino acid transport
LIS80_16820	COG2814	Major facilitator Superfamily
LIS80_16845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LIS80_16850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LIS80_16865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_16870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_16880	COG3739	integral membrane protein
LIS80_16900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_16915	COG0583	DNA-binding transcription factor activity
LIS80_16925	COG2890	protein-(glutamine-N5) methyltransferase activity
LIS80_16940	COG1193	negative regulation of DNA recombination
LIS80_16945	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LIS80_16950	COG1164	Oligoendopeptidase f
LIS80_16955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LIS80_16995	COG0640	Transcriptional regulator
LIS80_17000	COG0604	alcohol dehydrogenase
LIS80_17025	COG2808	Putative FMN-binding domain
LIS80_17030	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LIS80_17040	COG0385	Bile acid
LIS80_17045	COG0277	FAD linked oxidase domain protein
LIS80_17075	COG1285	pathogenesis
LIS80_17090	COG2514	catechol 2,3-dioxygenase activity
LIS80_17095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIS80_17100	COG1126	abc transporter atp-binding protein
LIS80_17105	COG0765	amino acid transport
LIS80_17110	COG2720	vancomycin resistance protein
LIS80_17150	COG0716	FMN binding
LIS80_17195	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_17205	COG0165	Argininosuccinate lyase
LIS80_17220	COG4145	pantothenate transmembrane transporter activity
LIS80_17270	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_17285	COG1657	PFAM Prenyltransferase squalene oxidase
LIS80_17290	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LIS80_17295	COG2962	Rard protein
LIS80_17300	COG3326	Membrane
LIS80_17315	COG0489	protein tyrosine kinase activity
LIS80_17325	COG0314	molybdopterin synthase activity
LIS80_17330	COG0303	'Molybdopterin
LIS80_17335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LIS80_17340	COG2116	formate transmembrane transporter activity
LIS80_17350	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LIS80_17355	COG5609	conserved protein (DUF2294)
LIS80_17360	COG2427	Protein of unknown function (DUF1641)
LIS80_17365	COG3383	formate dehydrogenase (NAD+) activity
LIS80_17370	COG0697	spore germination
LIS80_17415	COG2226	methyltransferase
LIS80_17420	COG4166	transmembrane transport
LIS80_17425	COG4166	transmembrane transport
LIS80_17430	COG4166	transmembrane transport
LIS80_17435	COG1301	dicarboxylic acid transport
LIS80_17440	COG1316	TRANSCRIPTIONal
LIS80_17450	COG1595	DNA-templated transcription, initiation
LIS80_17455	COG0346	lactoylglutathione lyase activity
LIS80_17465	COG1131	(ABC) transporter
LIS80_17475	COG0673	inositol 2-dehydrogenase activity
LIS80_17480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LIS80_17485	COG0187	DNA topoisomerase II activity
LIS80_17490	COG1832	CoA-binding protein
LIS80_17495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LIS80_17500	COG0745	RESPONSE REGULATOR receiver
LIS80_17510	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LIS80_17510	COG1328	CTP reductase activity
LIS80_17520	COG4841	protein insertion into membrane
LIS80_17525	COG0824	Thioesterase
LIS80_17555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIS80_17565	COG1132	(ABC) transporter
LIS80_17570	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LIS80_17600	COG2211	Major facilitator Superfamily
LIS80_17600	COG2211	Major facilitator Superfamily
LIS80_17605	COG4282	regulation of fungal-type cell wall biogenesis
LIS80_17625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LIS80_17650	COG0183	Belongs to the thiolase family
LIS80_17655	COG0318	PFAM AMP-dependent synthetase and ligase
LIS80_17660	COG1268	BioY protein
LIS80_17665	COG0318	PFAM AMP-dependent synthetase and ligase
LIS80_17680	COG1396	sequence-specific DNA binding
LIS80_17725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_17735	COG5002	protein histidine kinase activity
LIS80_17740	COG0400	carboxylic ester hydrolase activity
LIS80_17745	COG0346	lactoylglutathione lyase activity
LIS80_17750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LIS80_17760	COG0069	glutamate synthase activity
LIS80_17765	COG1902	pentaerythritol trinitrate reductase activity
LIS80_17770	COG1329	Transcriptional regulator
LIS80_17775	COG0010	Belongs to the arginase family
LIS80_17800	COG2226	methyltransferase
LIS80_17850	COG4846	Membrane protein involved in cytochrome C biogenesis
LIS80_17855	COG0785	Cytochrome C biogenesis protein
LIS80_17865	COG1473	amidohydrolase
LIS80_17875	COG1131	(ABC) transporter
LIS80_17885	COG0583	DNA-binding transcription factor activity
LIS80_17895	COG1346	cytolysis
LIS80_17910	COG0730	response to heat
LIS80_17920	COG3409	Peptidoglycan-binding domain 1 protein
LIS80_17920	COG5632	N-Acetylmuramoyl-L-alanine amidase
LIS80_17940	COG1132	(ABC) transporter
LIS80_17945	COG1132	(ABC) transporter
LIS80_17970	COG3639	organic phosphonate transmembrane transporter activity
LIS80_17975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LIS80_17980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIS80_17985	COG0737	Belongs to the 5'-nucleotidase family
LIS80_17995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LIS80_18015	COG1695	Transcriptional regulator
LIS80_18020	COG0174	glutamine synthetase
LIS80_18025	COG0789	Transcriptional regulator
LIS80_18030	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LIS80_18035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LIS80_18040	COG2860	membrane
LIS80_18045	COG0464	growth
LIS80_18075	COG1388	LysM domain
LIS80_18075	COG3584	3D domain protein
LIS80_18080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIS80_18080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LIS80_18080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LIS80_18085	COG1105	Belongs to the carbohydrate kinase PfkB family
LIS80_18090	COG1349	DNA-binding transcription factor activity
LIS80_18095	COG1979	alcohol dehydrogenase
LIS80_18100	COG2322	membrane
LIS80_18110	COG1113	amino acid transport
LIS80_18120	COG1408	metallophosphoesterase
LIS80_18125	COG2116	formate transmembrane transporter activity
LIS80_18140	COG2217	Heavy metal translocating P-type atpase
LIS80_18145	COG2608	mercury ion transmembrane transporter activity
LIS80_18150	COG1937	Protein conserved in bacteria
LIS80_18160	COG2819	hydrolase of the alpha beta superfamily
LIS80_18165	COG1120	ATPase activity
LIS80_18170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_18175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_18180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_18190	COG2169	Transcriptional regulator
LIS80_18195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LIS80_18200	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LIS80_18210	COG2364	Membrane
LIS80_18220	COG3300	MHYT domain
LIS80_18220	COG5001	Diguanylate cyclase
LIS80_18240	COG1380	Effector of murein hydrolase LrgA
LIS80_18245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_18265	COG3773	Cell wall hydrolase
LIS80_18280	COG1368	sulfuric ester hydrolase activity
LIS80_18285	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LIS80_18295	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LIS80_18315	COG4550	Control of competence regulator ComK, YlbF/YmcA
LIS80_18325	COG1013	pyruvate-flavodoxin oxidoreductase activity
LIS80_18330	COG0674	pyruvate-flavodoxin oxidoreductase activity
LIS80_18330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LIS80_18340	COG2359	stage V sporulation protein S
LIS80_18345	COG1692	metallophosphoesterase
LIS80_18350	COG1418	mRNA catabolic process
LIS80_18370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LIS80_18375	COG1426	Protein conserved in bacteria
LIS80_18390	COG0300	oxidoreductase activity
LIS80_18395	COG0612	Peptidase, M16
LIS80_18400	COG0612	Peptidase, M16
LIS80_18405	COG1079	Belongs to the binding-protein-dependent transport system permease family
LIS80_18410	COG4603	Belongs to the binding-protein-dependent transport system permease family
LIS80_18415	COG3845	ABC transporter
LIS80_18420	COG1744	ABC transporter substrate-binding protein PnrA-like
LIS80_18425	COG2188	Transcriptional regulator
LIS80_18430	COG1674	ftsk spoiiie
LIS80_18440	COG0740	serine-type endopeptidase activity
LIS80_18445	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LIS80_18455	COG0527	aspartate kinase activity
LIS80_18460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LIS80_18465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LIS80_18470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LIS80_18475	COG1873	PFAM PRC-barrel domain
LIS80_18480	COG0612	Peptidase, M16
LIS80_18485	COG0726	polysaccharide deacetylase
LIS80_18500	COG0196	riboflavin kinase activity
LIS80_18515	COG1550	Protein conserved in bacteria
LIS80_18525	COG1358	cellular component organization or biogenesis
LIS80_18530	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LIS80_18535	COG0195	Participates in both transcription termination and antitermination
LIS80_18555	COG0750	zinc metalloprotease
LIS80_18565	COG4589	Belongs to the CDS family
LIS80_18580	COG0528	UMP kinase activity
LIS80_18610	COG4974	Belongs to the 'phage' integrase family
LIS80_18620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LIS80_18625	COG0758	DNA mediated transformation
LIS80_18630	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LIS80_18670	COG1837	Belongs to the UPF0109 family
LIS80_18680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LIS80_18690	COG0552	protein localization to endoplasmic reticulum
LIS80_18695	COG1196	nuclear chromosome segregation
LIS80_18705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LIS80_18710	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_18715	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LIS80_18730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LIS80_18735	COG1461	Dihydroxyacetone kinase
LIS80_18740	COG1302	Protein conserved in bacteria
LIS80_18755	COG1564	THIamine pyrophosphokinase
LIS80_18760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LIS80_18770	COG0515	serine threonine protein kinase
LIS80_18770	COG2815	serine threonine protein kinase
LIS80_18775	COG0631	protein serine/threonine phosphatase activity
LIS80_18785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LIS80_18785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LIS80_18795	COG0242	peptide deformylase activity
LIS80_18800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LIS80_18805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LIS80_18825	COG1561	YicC-like family, N-terminal region
LIS80_18830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LIS80_18840	COG0006	proline dipeptidase activity
LIS80_18860	COG3069	C4-dicarboxylate transmembrane transporter activity
LIS80_18925	COG0564	pseudouridine synthase activity
LIS80_18945	COG3599	regulation of cell shape
LIS80_18950	COG2302	S4 RNA-binding domain
LIS80_18955	COG0762	integral membrane protein
LIS80_18965	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LIS80_18975	COG1873	PFAM PRC-barrel domain
LIS80_18980	COG1191	sigma factor activity
LIS80_18985	COG1191	sigma factor activity
LIS80_18995	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LIS80_19000	COG0849	cell division
LIS80_19005	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LIS80_19020	COG0772	Belongs to the SEDS family
LIS80_19035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LIS80_19040	COG0768	penicillin binding
LIS80_19045	COG0768	penicillin binding
LIS80_19050	COG4839	cell division protein FtsL
LIS80_19065	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LIS80_19080	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LIS80_19085	COG1399	metal-binding, possibly nucleic acid-binding protein
LIS80_19095	COG3480	Lon protease (S16) C-terminal proteolytic domain
LIS80_19100	COG1752	Esterase of the alpha-beta hydrolase superfamily
LIS80_19105	COG3314	Sporulation integral membrane protein YlbJ
LIS80_19115	COG0742	ribosomal rna small subunit methyltransferase
LIS80_19130	COG3679	Belongs to the UPF0342 family
LIS80_19135	COG0406	alpha-ribazole phosphatase activity
LIS80_19150	COG2340	Cysteine-rich secretory protein family
LIS80_19165	COG3344	reverse transcriptase
LIS80_19175	COG3336	cytochrome c oxidase
LIS80_19190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LIS80_19210	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LIS80_19215	COG0772	Belongs to the SEDS family
LIS80_19225	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LIS80_19230	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LIS80_19240	COG4896	Protein conserved in bacteria
LIS80_19255	COG1217	gtp-binding protein TYPA
LIS80_19265	COG0483	inositol monophosphate 1-phosphatase activity
LIS80_19285	COG1982	Orn Lys Arg decarboxylase major
LIS80_19335	COG0022	dehydrogenase e1 component
LIS80_19340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LIS80_19350	COG0242	peptide deformylase activity
LIS80_19355	COG0561	phosphatase activity
LIS80_19365	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LIS80_19370	COG0569	domain protein
LIS80_19390	COG0583	DNA-binding transcription factor activity
LIS80_19395	COG0517	IMP dehydrogenase activity
LIS80_19405	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LIS80_19415	COG4703	Protein of unknown function (DUF1797)
LIS80_19430	COG2200	EAL domain
LIS80_19435	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_19440	COG1408	metallophosphoesterase
LIS80_19450	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LIS80_19485	COG2814	Major facilitator Superfamily
LIS80_19515	COG3209	COG3209 Rhs family protein
LIS80_19525	COG2205	protein histidine kinase activity
LIS80_19535	COG0436	Aminotransferase
LIS80_19540	COG1609	Transcriptional regulator
LIS80_19545	COG3833	ABC-type maltose transport systems, permease component
LIS80_19550	COG1175	transmembrane transport
LIS80_19555	COG2182	Extracellular solute-binding protein
LIS80_19565	COG0366	Alpha amylase catalytic
LIS80_19570	COG3842	ATPase activity
LIS80_19610	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LIS80_19615	COG0183	Belongs to the thiolase family
LIS80_19645	COG1695	Transcriptional regulator
LIS80_19650	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_19670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LIS80_19675	COG0436	Aminotransferase
LIS80_19710	COG2084	Dehydrogenase
LIS80_19720	COG2199	diguanylate cyclase activity
LIS80_19725	COG0778	Nitroreductase
LIS80_19750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIS80_19750	COG1263	PTS System
LIS80_19750	COG2190	(PTS) system
LIS80_19755	COG3711	transcriptional antiterminator
LIS80_19765	COG2188	Transcriptional regulator
LIS80_19775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LIS80_19800	COG1547	Domain of unknown function (DUF309)
LIS80_19805	COG0456	acetyltransferase
LIS80_19815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LIS80_19820	COG4086	secreted protein
LIS80_19825	COG0561	phosphatase activity
LIS80_19830	COG0697	spore germination
LIS80_19845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIS80_19870	COG0733	neurotransmitter:sodium symporter activity
LIS80_19890	COG1686	Belongs to the peptidase S11 family
LIS80_19895	COG1725	Transcriptional regulator
LIS80_19900	COG1131	(ABC) transporter
LIS80_19915	COG1846	Transcriptional regulator
LIS80_19930	COG0598	Magnesium transport protein CorA
LIS80_19955	COG4974	Belongs to the 'phage' integrase family
LIS80_19965	COG0735	belongs to the Fur family
LIS80_19970	COG1300	Membrane
LIS80_19990	COG0667	Aldo Keto reductase
LIS80_19995	COG0656	L-ascorbic acid biosynthetic process
LIS80_20000	COG0456	acetyltransferase
LIS80_20000	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LIS80_20010	COG4085	toxin activity
LIS80_20010	COG1525	nuclease
LIS80_20010	COG0737	Belongs to the 5'-nucleotidase family
LIS80_20020	COG0596	Alpha beta hydrolase
LIS80_20025	COG2056	Na+-H+ antiporter family
LIS80_20030	COG1609	Transcriptional regulator
LIS80_20035	COG0456	acetyltransferase
LIS80_20040	COG1073	alpha beta
LIS80_20055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LIS80_20055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LIS80_20060	COG0307	riboflavin synthase, alpha
LIS80_20085	COG4106	trans-aconitate 2-methyltransferase activity
LIS80_20090	COG2226	methyltransferase
LIS80_20090	COG1073	alpha beta
LIS80_20105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LIS80_20115	COG1757	Na H antiporter
LIS80_20120	COG0737	Belongs to the 5'-nucleotidase family
LIS80_20130	COG1522	sequence-specific DNA binding
LIS80_20150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LIS80_20175	COG0300	oxidoreductase activity
LIS80_20180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_20185	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LIS80_20190	COG1760	l-serine dehydratase
LIS80_20195	COG1760	l-serine dehydratase
LIS80_20225	COG2195	Cleaves the N-terminal amino acid of tripeptides
LIS80_20230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_20245	COG1376	ErfK ybiS ycfS ynhG family protein
LIS80_20250	COG4129	membrane
LIS80_20255	COG1126	abc transporter atp-binding protein
LIS80_20260	COG0765	amino acid transport
LIS80_20265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIS80_20280	COG2323	membrane
LIS80_20285	COG0772	Belongs to the SEDS family
LIS80_20290	COG0508	dehydrogenase complex catalyzes the overall conversion of
LIS80_20295	COG0022	dehydrogenase e1 component
LIS80_20300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LIS80_20305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LIS80_20320	COG0280	phosphate acetyltransferase
LIS80_20325	COG3290	protein histidine kinase activity
LIS80_20325	COG3829	transcription factor binding
LIS80_20335	COG0584	glycerophosphoryl diester phosphodiesterase
LIS80_20340	COG3093	addiction module antidote protein HigA
LIS80_20345	COG0745	RESPONSE REGULATOR receiver
LIS80_20350	COG0750	zinc metalloprotease
LIS80_20355	COG0497	DNA recombination
LIS80_20365	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LIS80_20375	COG0142	geranyltranstransferase activity
LIS80_20400	COG1302	Protein conserved in bacteria
LIS80_20405	COG0439	Biotin carboxylase
LIS80_20410	COG0511	ligase activity, forming carbon-carbon bonds
LIS80_20455	COG3854	ATPases associated with a variety of cellular activities
LIS80_20480	COG0006	proline dipeptidase activity
LIS80_20495	COG3872	metal-dependent enzyme
LIS80_20525	COG0095	Lipoate-protein ligase
LIS80_20530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LIS80_20535	COG1609	Transcriptional regulator
LIS80_20545	COG2076	Multidrug Resistance protein
LIS80_20550	COG2076	Multidrug Resistance protein
LIS80_20585	COG1131	(ABC) transporter
LIS80_20590	COG1725	Transcriptional regulator
LIS80_20620	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LIS80_20675	COG4970	Tfp pilus assembly protein FimT
LIS80_20685	COG1459	type II secretion system
LIS80_20690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LIS80_20745	COG0646	methionine synthase
LIS80_20745	COG1410	methionine synthase
LIS80_20750	COG0646	methionine synthase
LIS80_20750	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LIS80_20755	COG0626	cystathionine gamma-synthase activity
LIS80_20760	COG0626	cystathionine gamma-synthase activity
LIS80_20780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_20790	COG1940	carbohydrate kinase activity
LIS80_20795	COG4483	Protein conserved in bacteria
LIS80_20800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LIS80_20805	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LIS80_20810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LIS80_20815	COG0704	Plays a role in the regulation of phosphate uptake
LIS80_20825	COG0581	inorganic phosphate transmembrane transporter activity
LIS80_20830	COG0573	inorganic phosphate transmembrane transporter activity
LIS80_20835	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LIS80_20840	COG0768	penicillin binding
LIS80_20845	COG0477	Major facilitator Superfamily
LIS80_20850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LIS80_20875	COG0735	belongs to the Fur family
LIS80_20880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LIS80_20885	COG1121	(ABC) transporter
LIS80_20890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_20920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LIS80_20925	COG2384	SAM-dependent methyltransferase
LIS80_20930	COG2010	Cytochrome c
LIS80_20935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LIS80_20940	COG0358	DNA primase activity
LIS80_20955	COG0517	IMP dehydrogenase activity
LIS80_20970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LIS80_20975	COG0295	cytidine deaminase activity
LIS80_20980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LIS80_20990	COG1480	7TM receptor with intracellular HD hydrolase
LIS80_20995	COG1702	phosphate starvation-inducible protein PhoH
LIS80_21010	COG1610	YqeY-like protein
LIS80_21015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LIS80_21020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LIS80_21025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LIS80_21055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LIS80_21060	COG1733	regulation of RNA biosynthetic process
LIS80_21085	COG1466	dna polymerase III delta subunit
LIS80_21095	COG0658	competence protein
LIS80_21095	COG2333	competence protein COMEC
LIS80_21100	COG2131	deaminase
LIS80_21105	COG1555	photosystem II stabilization
LIS80_21105	COG1596	polysaccharide export
LIS80_21110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LIS80_21115	COG2226	methyltransferase
LIS80_21120	COG0799	negative regulation of ribosome biogenesis
LIS80_21125	COG1713	HD superfamily hydrolase involved in NAD metabolism
LIS80_21135	COG1534	Rna-binding protein
LIS80_21145	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LIS80_21150	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LIS80_21175	COG1595	DNA-templated transcription, initiation
LIS80_21185	COG2357	RelA SpoT domain protein
LIS80_21195	COG1785	Belongs to the alkaline phosphatase family
LIS80_21200	COG0456	acetyltransferase
LIS80_21205	COG2267	carboxylic ester hydrolase activity
LIS80_21240	COG1404	Belongs to the peptidase S8 family
LIS80_21245	COG3186	Phenylalanine-4-hydroxylase
LIS80_21255	COG2514	catechol 2,3-dioxygenase activity
LIS80_21260	COG2259	Doxx family
LIS80_21300	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LIS80_21310	COG1012	belongs to the aldehyde dehydrogenase family
LIS80_21310	COG1454	alcohol dehydrogenase
LIS80_21315	COG0626	cystathionine gamma-synthase activity
LIS80_21320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LIS80_21345	COG0768	penicillin binding
LIS80_21360	COG0826	peptidase U32
LIS80_21365	COG0826	peptidase U32
LIS80_21370	COG4122	O-methyltransferase activity
LIS80_21375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LIS80_21405	COG0628	permease
LIS80_21425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LIS80_21440	COG1104	cysteine desulfurase activity
LIS80_21445	COG1959	2 iron, 2 sulfur cluster binding
LIS80_21450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LIS80_21460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LIS80_21490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LIS80_21500	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LIS80_21500	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LIS80_21505	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LIS80_21510	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LIS80_21510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LIS80_21520	COG2244	polysaccharide biosynthetic process
LIS80_21525	COG2323	membrane
LIS80_21535	COG1862	Preprotein translocase
LIS80_21565	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LIS80_21580	COG0697	spore germination
LIS80_21585	COG0640	Transcriptional regulator
LIS80_21610	COG0157	Belongs to the NadC ModD family
LIS80_21615	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LIS80_21620	COG1104	cysteine desulfurase activity
LIS80_21625	COG1827	regulation of RNA biosynthetic process
LIS80_21630	COG2258	MOSC domain
LIS80_21635	COG0077	Prephenate dehydratase
LIS80_21640	COG0577	efflux transmembrane transporter activity
LIS80_21645	COG0577	efflux transmembrane transporter activity
LIS80_21650	COG1136	(ABC) transporter
LIS80_21655	COG5002	protein histidine kinase activity
LIS80_21660	COG0745	RESPONSE REGULATOR receiver
LIS80_21670	COG3290	protein histidine kinase activity
LIS80_21680	COG2868	ribosomal protein
LIS80_21685	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LIS80_21690	COG1530	ribonuclease E activity
LIS80_21695	COG1994	Peptidase M50
LIS80_21700	COG0739	heme binding
LIS80_21705	COG2894	cell division
LIS80_21725	COG1077	Cell shape determining protein MreB Mrl
LIS80_21740	COG0477	Major facilitator Superfamily
LIS80_21745	COG2249	NAD(P)H dehydrogenase (quinone) activity
LIS80_21780	COG0285	dihydrofolate synthase activity
LIS80_21795	COG1388	LysM domain
LIS80_21805	COG0113	porphobilinogen synthase activity
LIS80_21810	COG1587	Uroporphyrinogen-III synthase
LIS80_21820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LIS80_21830	COG1846	Transcriptional regulator
LIS80_21835	COG1764	response to oxidative stress
LIS80_21850	COG1067	ATP-dependent peptidase activity
LIS80_21850	COG0470	DNA polymerase III
LIS80_21990	COG0622	Phosphoesterase
LIS80_22005	COG5401	PFAM Sporulation and spore germination
LIS80_22025	COG1309	transcriptional regulator
LIS80_22065	COG1196	nuclear chromosome segregation
LIS80_22090	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LIS80_22090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LIS80_22135	COG2197	response regulator
LIS80_22140	COG2233	PERMEase
LIS80_22145	COG0402	S-adenosylhomocysteine deaminase activity
LIS80_22150	COG1983	PspC domain protein
LIS80_22155	COG1396	sequence-specific DNA binding
LIS80_22160	COG0697	spore germination
LIS80_22170	COG1959	2 iron, 2 sulfur cluster binding
LIS80_22175	COG1668	transmembrane transport
LIS80_22180	COG4152	abc transporter atp-binding protein
LIS80_22185	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LIS80_22190	COG1360	Flagellar Motor Protein
LIS80_22195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LIS80_22200	COG1876	peptidase activity
LIS80_22205	COG0824	Thioesterase
LIS80_22210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LIS80_22215	COG1053	succinate dehydrogenase
LIS80_22220	COG2009	succinate dehydrogenase
LIS80_22225	COG1719	4-vinyl reductase, 4VR
LIS80_22235	COG3118	belongs to the thioredoxin family
LIS80_22240	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LIS80_22245	COG2086	electron transfer activity
LIS80_22250	COG1024	Enoyl-CoA hydratase
LIS80_22255	COG1309	transcriptional regulator
LIS80_22260	COG0318	PFAM AMP-dependent synthetase and ligase
LIS80_22275	COG2318	DinB family
LIS80_22300	COG1131	(ABC) transporter
LIS80_22305	COG2205	protein histidine kinase activity
LIS80_22310	COG0745	RESPONSE REGULATOR receiver
LIS80_22320	COG4895	conserved protein (DUF2196)
LIS80_22325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LIS80_22340	COG4509	Sortase family
LIS80_22345	COG1120	ATPase activity
LIS80_22360	COG5386	Cell surface protein
LIS80_22365	COG5386	Cell surface protein
LIS80_22370	COG1114	Component of the transport system for branched-chain amino acids
LIS80_22375	COG1187	pseudouridine synthase activity
LIS80_22385	COG1796	DNA polymerase
LIS80_22385	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LIS80_22390	COG1286	toxin biosynthetic process
LIS80_22435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LIS80_22445	COG1418	mRNA catabolic process
LIS80_22455	COG2814	Major facilitator Superfamily
LIS80_22460	COG1566	PFAM secretion protein HlyD family protein
LIS80_22465	COG1309	transcriptional regulator
LIS80_22470	COG1363	Peptidase, m42
LIS80_22495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LIS80_22505	COG1484	DNA-dependent DNA replication
LIS80_22510	COG3611	Membrane attachment protein
LIS80_22520	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LIS80_22525	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LIS80_22530	COG0237	dephospho-CoA kinase activity
LIS80_22535	COG1971	Probably functions as a manganese efflux pump
LIS80_22545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LIS80_22545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LIS80_22550	COG5002	protein histidine kinase activity
LIS80_22555	COG0745	RESPONSE REGULATOR receiver
LIS80_22575	COG0538	isocitrate dehydrogenase activity
LIS80_22580	COG0372	Belongs to the citrate synthase family
LIS80_22590	COG0628	permease
LIS80_22595	COG3030	protein affecting phage T7 exclusion by the F plasmid
LIS80_22620	COG1725	Transcriptional regulator
LIS80_22625	COG0281	malic enzyme
LIS80_22630	COG0587	DNA-directed DNA polymerase activity
LIS80_22645	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LIS80_22670	COG4109	DRTGG domain
LIS80_22685	COG0006	proline dipeptidase activity
LIS80_22725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_22730	COG0662	Cupin 2, conserved barrel domain protein
LIS80_22750	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_22755	COG0589	response to stress
LIS80_22825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_22850	COG0827	DNA restriction-modification system
LIS80_22855	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LIS80_22860	COG3874	Sporulation protein YtfJ
LIS80_22875	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LIS80_22885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LIS80_22900	COG1104	cysteine desulfurase activity
LIS80_22910	COG0583	DNA-binding transcription factor activity
LIS80_22915	COG0697	spore germination
LIS80_22920	COG1309	transcriptional regulator
LIS80_22925	COG1956	GAF domain-containing protein
LIS80_22930	COG0626	cystathionine gamma-synthase activity
LIS80_22960	COG1595	DNA-templated transcription, initiation
LIS80_22970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LIS80_22975	COG0454	-acetyltransferase
LIS80_22980	COG0517	IMP dehydrogenase activity
LIS80_22985	COG0123	including yeast histone deacetylase and acetoin utilization protein
LIS80_22990	COG2267	carboxylic ester hydrolase activity
LIS80_23000	COG0745	RESPONSE REGULATOR receiver
LIS80_23045	COG1609	Transcriptional regulator
LIS80_23050	COG4851	CamS sex pheromone cAM373 precursor
LIS80_23055	COG3118	belongs to the thioredoxin family
LIS80_23065	COG2309	aminopeptidase activity
LIS80_23085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_23100	COG1674	ftsk spoiiie
LIS80_23110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LIS80_23120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIS80_23125	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LIS80_23130	COG1363	Peptidase, m42
LIS80_23140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_23155	COG0510	thiamine kinase activity
LIS80_23160	COG1523	belongs to the glycosyl hydrolase 13 family
LIS80_23170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LIS80_23175	COG1349	DNA-binding transcription factor activity
LIS80_23180	COG1187	pseudouridine synthase activity
LIS80_23185	COG2244	polysaccharide biosynthetic process
LIS80_23190	COG2081	HI0933 family
LIS80_23195	COG2814	Major facilitator Superfamily
LIS80_23205	COG3832	glyoxalase III activity
LIS80_23225	COG1329	Transcriptional regulator
LIS80_23250	COG0314	molybdopterin synthase activity
LIS80_23265	COG1763	Mo-molybdopterin cofactor biosynthetic process
LIS80_23270	COG0303	'Molybdopterin
LIS80_23280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LIS80_23285	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LIS80_23305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LIS80_23315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LIS80_23355	COG2814	Major facilitator Superfamily
LIS80_23360	COG0475	glutathione-regulated potassium exporter activity
LIS80_23365	COG0490	domain, Protein
LIS80_23370	COG0582	viral genome integration into host DNA
LIS80_23380	COG1136	(ABC) transporter
LIS80_23400	COG1242	4 iron, 4 sulfur cluster binding
LIS80_23405	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LIS80_23410	COG4152	abc transporter atp-binding protein
LIS80_23420	COG1794	racemase activity, acting on amino acids and derivatives
LIS80_23445	COG2267	carboxylic ester hydrolase activity
LIS80_23450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LIS80_23455	COG0671	phosphoesterase, PA-phosphatase related
LIS80_23460	COG0438	transferase activity, transferring glycosyl groups
LIS80_23470	COG0521	Mo-molybdopterin cofactor biosynthetic process
LIS80_23485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_23530	COG5002	protein histidine kinase activity
LIS80_23535	COG4191	Histidine kinase
LIS80_23540	COG2267	carboxylic ester hydrolase activity
LIS80_23545	COG1368	sulfuric ester hydrolase activity
LIS80_23570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LIS80_23575	COG1116	anion transmembrane transporter activity
LIS80_23580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LIS80_23605	COG0494	nUDIX hydrolase
LIS80_23640	COG0288	reversible hydration of carbon dioxide
LIS80_23645	COG1271	oxidase subunit
LIS80_23650	COG1294	oxidase, subunit
LIS80_23670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_23695	COG1842	Phage shock protein A
LIS80_23730	COG5002	protein histidine kinase activity
LIS80_23735	COG0745	RESPONSE REGULATOR receiver
LIS80_23765	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LIS80_23770	COG1597	lipid kinase activity
LIS80_23790	COG0577	efflux transmembrane transporter activity
LIS80_23795	COG1136	(ABC) transporter
LIS80_23810	COG0586	Pfam SNARE associated Golgi protein
LIS80_23820	COG4977	sequence-specific DNA binding
LIS80_23830	COG0577	efflux transmembrane transporter activity
LIS80_23835	COG1136	(ABC) transporter
LIS80_23840	COG3708	Transcriptional regulator
LIS80_23840	COG2207	Transcriptional regulator
LIS80_23845	COG5658	integral membrane protein
LIS80_23850	COG0640	Transcriptional regulator
LIS80_23855	COG0745	RESPONSE REGULATOR receiver
LIS80_23860	COG2205	protein histidine kinase activity
LIS80_23865	COG0577	efflux transmembrane transporter activity
LIS80_23870	COG0577	efflux transmembrane transporter activity
LIS80_23875	COG1136	(ABC) transporter
LIS80_23880	COG0577	efflux transmembrane transporter activity
LIS80_23895	COG2188	Transcriptional regulator
LIS80_23915	COG3964	amidohydrolase
LIS80_23935	COG4948	Mandelate Racemase Muconate Lactonizing
LIS80_23945	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LIS80_23950	COG0596	Alpha beta hydrolase
LIS80_23960	COG1169	isochorismate synthase
LIS80_23965	COG1575	Belongs to the MenA family. Type 1 subfamily
LIS80_23970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LIS80_23990	COG0058	SHG alpha-glucan phosphorylase activity
LIS80_24000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LIS80_24020	COG1404	Belongs to the peptidase S8 family
LIS80_24120	COG0544	peptidyl-prolyl cis-trans isomerase activity
LIS80_24155	COG1285	pathogenesis
LIS80_24160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LIS80_24175	COG2155	Conserved Protein
LIS80_24180	COG1098	S1 RNA binding domain
LIS80_24185	COG0436	Aminotransferase
LIS80_24190	COG1522	sequence-specific DNA binding
LIS80_24195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LIS80_24200	COG2267	carboxylic ester hydrolase activity
LIS80_24210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LIS80_24230	COG5018	Exonuclease
LIS80_24235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LIS80_24255	COG2050	protein possibly involved in aromatic compounds catabolism
LIS80_24265	COG1268	BioY protein
LIS80_24270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LIS80_24275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LIS80_24290	COG3584	3D domain protein
LIS80_24305	COG1252	NADH dehydrogenase
LIS80_24315	COG3708	Transcriptional regulator
LIS80_24330	COG1683	Conserved Protein
LIS80_24345	COG0316	Belongs to the HesB IscA family
LIS80_24360	COG1252	NADH dehydrogenase
LIS80_24375	COG0390	transport system, permease component
LIS80_24380	COG2824	Alkylphosphonate utilization operon protein PhnA
LIS80_24420	COG4837	Protein of unknown function (DUF1462)
LIS80_24425	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LIS80_24435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LIS80_24440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LIS80_24455	COG2249	NAD(P)H dehydrogenase (quinone) activity
LIS80_24465	COG0647	UMP catabolic process
LIS80_24475	COG2445	Protein of unknown function DUF86
LIS80_24480	COG1494	fructose-1,6-bisphosphatase
LIS80_24495	COG4470	Protein conserved in bacteria
LIS80_24505	COG0789	Transcriptional regulator
LIS80_24510	COG4377	Putative membrane peptidase family (DUF2324)
LIS80_24535	COG0739	heme binding
LIS80_24545	COG3377	Domain of unknown function (DUF1805)
LIS80_24550	COG0737	Belongs to the 5'-nucleotidase family
LIS80_24555	COG0719	Fe-S assembly protein
LIS80_24560	COG0822	iron-sulfur transferase activity
LIS80_24565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LIS80_24570	COG0719	Fe-S assembly protein
LIS80_24575	COG0396	ATPase activity
LIS80_24580	COG1464	Belongs to the NlpA lipoprotein family
LIS80_24585	COG1464	Belongs to the NlpA lipoprotein family
LIS80_24590	COG2011	ABC-type metal ion transport system permease component
LIS80_24595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LIS80_24605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIS80_24610	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LIS80_24620	COG1393	Belongs to the ArsC family
LIS80_24675	COG1396	sequence-specific DNA binding
LIS80_24685	COG1309	transcriptional regulator
LIS80_24690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_24695	COG1960	acyl-CoA dehydrogenase activity
LIS80_24700	COG0183	Belongs to the thiolase family
LIS80_24705	COG1250	3-hydroxyacyl-CoA dehydrogenase
LIS80_24705	COG1024	Enoyl-CoA hydratase
LIS80_24715	COG1686	Belongs to the peptidase S11 family
LIS80_24730	COG0011	TIGRFAM Protein of
LIS80_24735	COG0840	transmembrane signaling receptor activity
LIS80_24760	COG2814	Major facilitator Superfamily
LIS80_24765	COG0531	amino acid
LIS80_24790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_24825	COG0586	Pfam SNARE associated Golgi protein
LIS80_24835	COG1376	ErfK ybiS ycfS ynhG family protein
LIS80_24840	COG0745	RESPONSE REGULATOR receiver
LIS80_24845	COG5002	protein histidine kinase activity
LIS80_24875	COG0840	transmembrane signaling receptor activity
LIS80_24880	COG2151	metal-sulfur cluster biosynthetic enzyme
LIS80_24885	COG3227	Zinc metalloprotease (Elastase)
LIS80_24890	COG1741	Belongs to the pirin family
LIS80_24905	COG0475	glutathione-regulated potassium exporter activity
LIS80_24910	COG0490	domain, Protein
LIS80_24915	COG1115	amino acid carrier protein
LIS80_24920	COG0783	Belongs to the Dps family
LIS80_24935	COG1611	Belongs to the LOG family
LIS80_24955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_24960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_24965	COG1115	amino acid carrier protein
LIS80_24970	COG1115	amino acid carrier protein
LIS80_24975	COG2910	NAD(P)H-binding
LIS80_24990	COG0656	L-ascorbic acid biosynthetic process
LIS80_24995	COG2814	Major facilitator Superfamily
LIS80_25000	COG1733	regulation of RNA biosynthetic process
LIS80_25010	COG1252	NADH dehydrogenase
LIS80_25015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LIS80_25045	COG3290	protein histidine kinase activity
LIS80_25045	COG0840	transmembrane signaling receptor activity
LIS80_25080	COG0488	(ABC) transporter
LIS80_25085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_25130	COG1136	(ABC) transporter
LIS80_25150	COG0586	Pfam SNARE associated Golgi protein
LIS80_25155	COG3963	phosphatidate phosphatase activity
LIS80_25205	COG3708	Transcriptional regulator
LIS80_25205	COG2207	Transcriptional regulator
LIS80_25220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LIS80_25225	COG2814	Major facilitator Superfamily
LIS80_25235	COG0640	Transcriptional regulator
LIS80_25240	COG2311	Membrane
LIS80_25260	COG0557	exoribonuclease II activity
LIS80_25265	COG1647	Serine aminopeptidase, S33
LIS80_25270	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LIS80_25275	COG1346	cytolysis
LIS80_25310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LIS80_25325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LIS80_25335	COG1668	transmembrane transport
LIS80_25340	COG4152	abc transporter atp-binding protein
LIS80_25360	COG0142	geranyltranstransferase activity
LIS80_25370	COG4585	Histidine kinase
LIS80_25375	COG2197	response regulator
LIS80_25440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIS80_25455	COG2323	membrane
LIS80_25465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIS80_25475	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LIS80_25485	COG1051	belongs to the nudix hydrolase family
LIS80_25495	COG0492	ferredoxin-NADP+ reductase activity
LIS80_25500	COG0457	Tetratricopeptide repeat
LIS80_25505	COG0110	maltose O-acetyltransferase activity
LIS80_25525	COG1950	PFAM Membrane protein of
LIS80_25535	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LIS80_25550	COG0789	Transcriptional regulator
LIS80_25585	COG0583	DNA-binding transcription factor activity
LIS80_25595	COG0655	NAD(P)H dehydrogenase (quinone) activity
LIS80_25610	COG1132	(ABC) transporter
LIS80_25615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LIS80_25620	COG3409	Peptidoglycan-binding domain 1 protein
LIS80_25620	COG0793	Belongs to the peptidase S41A family
LIS80_25625	COG2177	Part of the ABC transporter FtsEX involved in
LIS80_25630	COG2884	Cell division ATP-binding protein ftsE
LIS80_25650	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LIS80_25655	COG1278	Cold shock
LIS80_25660	COG1040	competence protein
LIS80_25665	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LIS80_25670	COG0791	NLP P60 protein
LIS80_25670	COG1388	LysM domain
LIS80_25675	COG1733	regulation of RNA biosynthetic process
LIS80_25680	COG1307	EDD domain protein, DegV family
LIS80_25685	COG1739	Uncharacterized protein family UPF0029
LIS80_25705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LIS80_25710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LIS80_25715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LIS80_25725	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LIS80_25725	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LIS80_25745	COG1486	melibiose metabolic process
LIS80_25750	COG1447	Phosphotransferase system cellobiose-specific component IIA
LIS80_25755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LIS80_25765	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LIS80_25785	COG1447	Phosphotransferase system cellobiose-specific component IIA
LIS80_25795	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LIS80_25800	COG1301	dicarboxylic acid transport
LIS80_25810	COG0346	lactoylglutathione lyase activity
LIS80_25830	COG1511	domain protein
LIS80_25835	COG0583	DNA-binding transcription factor activity
LIS80_25840	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LIS80_25850	COG1271	oxidase subunit
LIS80_25855	COG1294	oxidase, subunit
LIS80_25860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LIS80_25870	COG1620	l-lactate permease
LIS80_25880	COG2389	metal-binding protein
LIS80_25890	COG1368	sulfuric ester hydrolase activity
LIS80_25900	COG0791	NLP P60 protein
LIS80_25900	COG1388	LysM domain
LIS80_25905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_25915	COG1215	transferase activity, transferring glycosyl groups
LIS80_25920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LIS80_25925	COG1388	LysM domain
LIS80_25925	COG3584	3D domain protein
LIS80_25950	COG4715	Zinc finger, swim domain protein
LIS80_25955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LIS80_25995	COG0577	efflux transmembrane transporter activity
LIS80_26000	COG1136	(ABC) transporter
LIS80_26025	COG5002	protein histidine kinase activity
LIS80_26030	COG0745	RESPONSE REGULATOR receiver
LIS80_26035	COG1482	cell wall glycoprotein biosynthetic process
LIS80_26040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LIS80_26040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LIS80_26040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIS80_26045	COG3711	transcriptional antiterminator
LIS80_26045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIS80_26050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LIS80_26070	COG0456	acetyltransferase
LIS80_26090	COG3475	LICD family
LIS80_26100	COG1316	TRANSCRIPTIONal
LIS80_26105	COG1482	cell wall glycoprotein biosynthetic process
LIS80_26110	COG0662	Cupin 2, conserved barrel domain protein
LIS80_26110	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LIS80_26130	COG0463	Glycosyl transferase, family 2
LIS80_26140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LIS80_26145	COG4464	protein tyrosine phosphatase activity
LIS80_26150	COG0489	protein tyrosine kinase activity
LIS80_26155	COG3944	biosynthesis protein
LIS80_26160	COG0489	protein tyrosine kinase activity
LIS80_26175	COG1609	Transcriptional regulator
LIS80_26185	COG0739	heme binding
LIS80_26200	COG3279	Response regulator of the LytR AlgR family
LIS80_26205	COG2385	sporulation resulting in formation of a cellular spore
LIS80_26220	COG4836	Membrane
LIS80_26225	COG1007	ATP synthesis coupled electron transport
LIS80_26230	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LIS80_26235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LIS80_26275	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LIS80_26290	COG3300	MHYT domain
LIS80_26290	COG5001	Diguanylate cyclase
LIS80_26340	COG0356	it plays a direct role in the translocation of protons across the membrane
LIS80_26375	COG0698	ribose 5-phosphate isomerase
LIS80_26385	COG2190	(PTS) system
LIS80_26390	COG2259	Doxx family
LIS80_26395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LIS80_26410	COG0009	L-threonylcarbamoyladenylate synthase
LIS80_26425	COG2890	protein-(glutamine-N5) methyltransferase activity
LIS80_26445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LIS80_26450	COG1494	fructose-1,6-bisphosphatase
LIS80_26470	COG4821	SIS domain
LIS80_26490	COG1960	acyl-CoA dehydrogenase activity
LIS80_26495	COG1960	acyl-CoA dehydrogenase activity
LIS80_26500	COG1250	3-hydroxyacyl-CoA dehydrogenase
LIS80_26505	COG0183	Belongs to the thiolase family
LIS80_26510	COG2181	nitrate reductase activity
LIS80_26510	COG0247	lactate metabolic process
LIS80_26515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIS80_26525	COG3300	MHYT domain
LIS80_26525	COG5001	Diguanylate cyclase
LIS80_26545	COG2197	response regulator
LIS80_26550	COG4585	Histidine kinase
LIS80_26555	COG0842	Transport permease protein
LIS80_26560	COG1131	(ABC) transporter
LIS80_26565	COG0024	Methionine aminopeptidase
LIS80_26585	COG2234	aminopeptidase activity
LIS80_26605	COG1595	DNA-templated transcription, initiation
LIS80_26615	COG4506	Protein conserved in bacteria
LIS80_26620	COG1619	proteins homologs of microcin C7 resistance protein MccF
LIS80_26645	COG2814	Major facilitator Superfamily
LIS80_26650	COG0789	Transcriptional regulator
LIS80_26655	COG0584	glycerophosphoryl diester phosphodiesterase
LIS80_26660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIS80_26670	COG1994	Peptidase M50
LIS80_26680	COG1078	dGTPase activity
LIS80_26685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_26690	COG1120	ATPase activity
LIS80_26695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_26700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_26720	COG0095	Lipoate-protein ligase
LIS80_26725	COG0280	phosphate acetyltransferase
LIS80_26740	COG3773	Cell wall hydrolase
LIS80_26750	COG2363	Small membrane protein
LIS80_26760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LIS80_26765	COG2233	PERMEase
LIS80_26770	COG0561	phosphatase activity
LIS80_26775	COG2814	Major facilitator Superfamily
LIS80_26785	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LIS80_26790	COG1131	(ABC) transporter
LIS80_26795	COG2755	lipolytic protein G-D-S-L family
LIS80_26800	COG1609	Transcriptional regulator
LIS80_26810	COG0460	homoserine dehydrogenase
LIS80_26820	COG2873	o-acetylhomoserine
LIS80_26825	COG1011	Hydrolase
LIS80_26830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LIS80_26840	COG2197	response regulator
LIS80_26845	COG2203	Gaf domain
LIS80_26845	COG4585	Histidine kinase
LIS80_26850	COG0351	phosphomethylpyrimidine kinase
LIS80_26855	COG3706	GGDEF domain
LIS80_26860	COG2879	small protein
LIS80_26865	COG1966	Carbon starvation protein
LIS80_26870	COG3279	Response regulator of the LytR AlgR family
LIS80_26875	COG0477	Major facilitator Superfamily
LIS80_26885	COG0438	transferase activity, transferring glycosyl groups
LIS80_26900	COG0840	transmembrane signaling receptor activity
LIS80_26910	COG1607	acyl-coa hydrolase
LIS80_26915	COG1216	Glycosyl transferase, family 2
LIS80_26930	COG1216	Glycosyl transferase, family 2
LIS80_26945	COG0488	(ABC) transporter
LIS80_26950	COG1309	transcriptional regulator
LIS80_26955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LIS80_26960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LIS80_26960	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LIS80_26965	COG0628	permease
LIS80_26980	COG3279	Response regulator of the LytR AlgR family
LIS80_26985	COG3275	phosphorelay sensor kinase activity
LIS80_26995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LIS80_27000	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LIS80_27005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LIS80_27050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LIS80_27055	COG1272	protein, Hemolysin III
LIS80_27075	COG1164	Oligoendopeptidase f
LIS80_27095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LIS80_27100	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LIS80_27105	COG4853	Protein conserved in bacteria
LIS80_27110	COG4863	YycH protein
LIS80_27115	COG5002	protein histidine kinase activity
LIS80_27120	COG0745	RESPONSE REGULATOR receiver
LIS80_27150	COG0305	Participates in initiation and elongation during chromosome replication
LIS80_27160	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LIS80_27165	COG4241	membrane
LIS80_27175	COG0629	single-stranded DNA binding
LIS80_27185	COG0012	GTP binding
LIS80_27190	COG4481	Protein conserved in bacteria
LIS80_27195	COG0668	transmembrane transport
LIS80_27205	COG1475	DNA binding
LIS80_27210	COG1192	Involved in chromosome partitioning
LIS80_27235	COG1847	R3H domain protein
LIS80_27240	COG0706	membrane insertase activity
LIS80_27250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LIS80_27390	COG2311	Membrane
LIS80_27430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LIS80_27460	COG2002	toxin-antitoxin pair type II binding
LIS80_27470	COG4974	Belongs to the 'phage' integrase family
LIS80_27545	COG3708	Transcriptional regulator
LIS80_27545	COG2207	Transcriptional regulator
LIS80_27620	COG3655	Transcriptional regulator
LIS80_27635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIS80_27640	COG2323	membrane
LIS80_27665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIS80_27680	COG2323	membrane
LIS80_27705	COG0697	spore germination
LIS80_27720	COG1733	regulation of RNA biosynthetic process
LIS80_27730	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LIS80_27740	COG1181	Belongs to the D-alanine--D-alanine ligase family
LIS80_27740	COG2918	glutathione biosynthetic process
LIS80_27780	COG1335	isochorismatase
LIS80_27785	COG4990	cell redox homeostasis
LIS80_27790	COG0745	RESPONSE REGULATOR receiver
LIS80_27825	COG1196	nuclear chromosome segregation
LIS80_27860	COG0640	Transcriptional regulator
LIS80_27880	COG0640	Transcriptional regulator
LIS80_27885	COG0798	PFAM Bile acid sodium symporter
LIS80_27925	COG4974	Belongs to the 'phage' integrase family
LIS80_27940	COG0457	Tetratricopeptide repeat
LIS80_28060	COG3344	reverse transcriptase
LIS80_28080	COG3344	reverse transcriptase
LIS80_28130	COG1396	sequence-specific DNA binding
LIS80_28155	COG3397	chitin binding
LIS80_28190	COG0791	NLP P60 protein
LIS80_28190	COG1388	LysM domain
LIS80_28190	COG3103	Sh3 type 3 domain protein
LIS80_28235	COG0640	Transcriptional regulator
LIS80_28395	COG4712	double-strand break repair protein