locus-tag	class	description
FOW48_00010	COG0592	DNA-directed DNA polymerase activity
FOW48_00015	COG2501	S4 domain
FOW48_00025	COG0187	DNA topoisomerase II activity
FOW48_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOW48_00065	COG0517	IMP dehydrogenase activity
FOW48_00065	COG0516	GMP reductase activity
FOW48_00070	COG1686	Belongs to the peptidase S11 family
FOW48_00105	COG1428	Deoxynucleoside kinase
FOW48_00110	COG1335	isochorismatase
FOW48_00115	COG0590	tRNA wobble adenosine to inosine editing
FOW48_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOW48_00180	COG1982	Orn Lys Arg decarboxylase major
FOW48_00190	COG0470	DNA polymerase III
FOW48_00195	COG1774	PSP1 C-terminal conserved region
FOW48_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOW48_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOW48_00220	COG2002	toxin-antitoxin pair type II binding
FOW48_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOW48_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOW48_00230	COG0084	hydrolase, TatD family'
FOW48_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOW48_00250	COG4466	Protein conserved in bacteria
FOW48_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOW48_00270	COG0251	oxidation-reduction process
FOW48_00285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOW48_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOW48_00305	COG2002	toxin-antitoxin pair type II binding
FOW48_00310	COG2244	polysaccharide biosynthetic process
FOW48_00315	COG3956	TIGRFAM MazG family protein
FOW48_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOW48_00340	COG1098	S1 RNA binding domain
FOW48_00355	COG2208	phosphoserine phosphatase activity
FOW48_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOW48_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOW48_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOW48_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
FOW48_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOW48_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOW48_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOW48_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOW48_00420	COG1396	sequence-specific DNA binding
FOW48_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOW48_00515	COG3880	PFAM UvrB UvrC protein
FOW48_00525	COG0542	response to heat
FOW48_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOW48_00540	COG4956	integral membrane protein (PIN domain superfamily)
FOW48_00560	COG1045	serine acetyltransferase
FOW48_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOW48_00580	COG3688	RNA-binding protein containing a PIN domain
FOW48_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOW48_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOW48_00600	COG0250	Participates in transcription elongation, termination and antitermination
FOW48_00625	COG2813	Specifically methylates the guanine in position
FOW48_00640	COG1358	cellular component organization or biogenesis
FOW48_00750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOW48_00775	COG0201	protein transport
FOW48_00785	COG0024	Methionine aminopeptidase
FOW48_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOW48_00825	COG1122	ATPase activity
FOW48_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOW48_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOW48_00860	COG0489	protein tyrosine kinase activity
FOW48_00870	COG2194	sulfuric ester hydrolase activity
FOW48_00875	COG0726	polysaccharide deacetylase
FOW48_00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOW48_00960	COG4856	YbbR-like protein
FOW48_00980	COG0596	Alpha beta hydrolase
FOW48_01000	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOW48_01035	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_01040	COG2011	ABC-type metal ion transport system permease component
FOW48_01050	COG1464	Belongs to the NlpA lipoprotein family
FOW48_01065	COG0277	FAD linked oxidase domain protein
FOW48_01070	COG2271	Major facilitator Superfamily
FOW48_01080	COG2814	Major facilitator Superfamily
FOW48_01095	COG0601	transmembrane transport
FOW48_01100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOW48_01105	COG0444	Belongs to the ABC transporter superfamily
FOW48_01110	COG4608	Belongs to the ABC transporter superfamily
FOW48_01115	COG4166	transmembrane transport
FOW48_01130	COG4166	transmembrane transport
FOW48_01135	COG4166	transmembrane transport
FOW48_01140	COG0656	L-ascorbic acid biosynthetic process
FOW48_01160	COG4149	molybdate abc transporter
FOW48_01165	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOW48_01170	COG1910	domain protein
FOW48_01185	COG0697	spore germination
FOW48_01200	COG0204	Acyl-transferase
FOW48_01210	COG1609	Transcriptional regulator
FOW48_01220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOW48_01230	COG0084	hydrolase, TatD family'
FOW48_01235	COG5298	Protein conserved in bacteria
FOW48_01255	COG0488	(ABC) transporter
FOW48_01265	COG0747	negative chemotaxis
FOW48_01270	COG0747	negative chemotaxis
FOW48_01275	COG0601	transmembrane transport
FOW48_01280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOW48_01285	COG0444	Belongs to the ABC transporter superfamily
FOW48_01295	COG0561	phosphatase activity
FOW48_01330	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FOW48_01335	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOW48_01345	COG0531	amino acid
FOW48_01360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOW48_01370	COG4294	response to UV
FOW48_01375	COG0705	Rhomboid family
FOW48_01385	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOW48_01390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOW48_01395	COG0864	Transcriptional regulator
FOW48_01400	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOW48_01405	COG2183	response to ionizing radiation
FOW48_01500	COG0802	atpase or kinase
FOW48_01505	COG1214	PFAM Peptidase M22, glycoprotease
FOW48_01510	COG0456	acetyltransferase
FOW48_01520	COG0488	(ABC) transporter
FOW48_01535	COG1266	CAAX protease self-immunity
FOW48_01555	COG2252	PERMEase
FOW48_01565	COG5002	protein histidine kinase activity
FOW48_01595	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOW48_01625	COG2226	methyltransferase
FOW48_01645	COG1215	transferase activity, transferring glycosyl groups
FOW48_01665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOW48_01695	COG0697	spore germination
FOW48_01725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOW48_01730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOW48_01735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOW48_01745	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOW48_01760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOW48_01770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOW48_01785	COG0151	Belongs to the GarS family
FOW48_01815	COG0210	DNA helicase
FOW48_01825	COG4851	CamS sex pheromone cAM373 precursor
FOW48_01840	COG1335	isochorismatase
FOW48_01850	COG2011	ABC-type metal ion transport system permease component
FOW48_01870	COG0003	Pfam Anion-transporting ATPase
FOW48_01875	COG1846	Transcriptional regulator
FOW48_01880	COG4682	membrane
FOW48_01900	COG1597	lipid kinase activity
FOW48_01905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOW48_01910	COG0546	phosphoglycolate phosphatase activity
FOW48_01915	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOW48_01925	COG1012	belongs to the aldehyde dehydrogenase family
FOW48_01930	COG2076	Multidrug Resistance protein
FOW48_01935	COG2309	aminopeptidase activity
FOW48_01945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOW48_01950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOW48_01955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOW48_01965	COG0028	Belongs to the TPP enzyme family
FOW48_01975	COG4807	Protein conserved in bacteria
FOW48_02000	COG0673	inositol 2-dehydrogenase activity
FOW48_02005	COG0277	FAD linked oxidase domain protein
FOW48_02015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOW48_02035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOW48_02040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOW48_02050	COG2814	Major facilitator Superfamily
FOW48_02060	COG4807	Protein conserved in bacteria
FOW48_02090	COG1473	amidohydrolase
FOW48_02105	COG0450	alkyl hydroperoxide reductase
FOW48_02110	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FOW48_02120	COG0235	Class ii aldolase
FOW48_02135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOW48_02140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOW48_02145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOW48_02165	COG0166	Belongs to the GPI family
FOW48_02205	COG3541	Predicted nucleotidyltransferase
FOW48_02210	COG2814	Major facilitator Superfamily
FOW48_02215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOW48_02215	COG0723	plastoquinol--plastocyanin reductase activity
FOW48_02240	COG0765	amino acid transport
FOW48_02245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOW48_02255	COG0840	transmembrane signaling receptor activity
FOW48_02260	COG0366	Alpha amylase catalytic
FOW48_02265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOW48_02265	COG2190	(PTS) system
FOW48_02265	COG1263	PTS System
FOW48_02285	COG1695	Transcriptional regulator
FOW48_02295	COG0577	efflux transmembrane transporter activity
FOW48_02300	COG1136	(ABC) transporter
FOW48_02325	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FOW48_02360	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOW48_02375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOW48_02385	COG1116	anion transmembrane transporter activity
FOW48_02395	COG0488	(ABC) transporter
FOW48_02445	COG2270	Major facilitator Superfamily
FOW48_02475	COG2310	stress, protein
FOW48_02480	COG2310	stress, protein
FOW48_02485	COG2310	stress, protein
FOW48_02490	COG0861	Integral membrane protein TerC family
FOW48_02500	COG3853	Toxic anion resistance protein (TelA)
FOW48_02515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOW48_02525	COG1295	ribonuclease BN
FOW48_02530	COG2217	Heavy metal translocating P-type atpase
FOW48_02535	COG0697	spore germination
FOW48_02560	COG0586	Pfam SNARE associated Golgi protein
FOW48_02575	COG3871	stress protein (general stress protein 26)
FOW48_02580	COG0387	Pfam Sodium calcium exchanger
FOW48_02590	COG0535	radical SAM domain protein
FOW48_02610	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOW48_02640	COG0833	amino acid
FOW48_02645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOW48_02670	COG2066	Belongs to the glutaminase family
FOW48_02680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOW48_02680	COG1263	PTS System
FOW48_02685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOW48_02700	COG0463	Glycosyl transferase, family 2
FOW48_02710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOW48_02710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOW48_02730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOW48_02750	COG0402	S-adenosylhomocysteine deaminase activity
FOW48_02755	COG1090	epimerase
FOW48_02785	COG1988	membrane-bound metal-dependent
FOW48_02790	COG1194	a g-specific adenine glycosylase
FOW48_02815	COG1132	(ABC) transporter
FOW48_02820	COG4129	membrane
FOW48_02825	COG0070	glutamate synthase
FOW48_02825	COG0069	glutamate synthase activity
FOW48_02825	COG0067	glutamate synthase
FOW48_02835	COG4555	ABC transporter
FOW48_02855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOW48_02860	COG0735	belongs to the Fur family
FOW48_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOW48_02990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOW48_03000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOW48_03010	COG2766	serine protein kinase
FOW48_03030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOW48_03040	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOW48_03045	COG2268	Band 7 protein
FOW48_03055	COG3290	protein histidine kinase activity
FOW48_03065	COG2851	Citrate transporter
FOW48_03090	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOW48_03095	COG3842	ATPase activity
FOW48_03100	COG1175	transmembrane transport
FOW48_03105	COG0395	ABC-type sugar transport system, permease component
FOW48_03115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOW48_03120	COG0745	RESPONSE REGULATOR receiver
FOW48_03125	COG5002	protein histidine kinase activity
FOW48_03135	COG4990	cell redox homeostasis
FOW48_03145	COG0697	spore germination
FOW48_03150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOW48_03160	COG5002	protein histidine kinase activity
FOW48_03165	COG0745	RESPONSE REGULATOR receiver
FOW48_03170	COG0456	acetyltransferase
FOW48_03170	COG0454	-acetyltransferase
FOW48_03175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOW48_03180	COG3383	formate dehydrogenase (NAD+) activity
FOW48_03185	COG2427	Protein of unknown function (DUF1641)
FOW48_03200	COG0531	amino acid
FOW48_03205	COG0640	Transcriptional regulator
FOW48_03210	COG2217	Heavy metal translocating P-type atpase
FOW48_03215	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOW48_03230	COG3227	Zinc metalloprotease (Elastase)
FOW48_03250	COG2720	vancomycin resistance protein
FOW48_03255	COG1316	TRANSCRIPTIONal
FOW48_03260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOW48_03265	COG0346	lactoylglutathione lyase activity
FOW48_03270	COG1253	flavin adenine dinucleotide binding
FOW48_03275	COG1027	Aspartate ammonia-lyase
FOW48_03285	COG1620	l-lactate permease
FOW48_03300	COG3104	oligopeptide transport
FOW48_03305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOW48_03310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOW48_03315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOW48_03325	COG2226	methyltransferase
FOW48_03330	COG0156	8-amino-7-oxononanoate synthase activity
FOW48_03340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOW48_03350	COG4548	von Willebrand factor, type A
FOW48_03355	COG0714	Associated with various cellular activities
FOW48_03380	COG0531	amino acid
FOW48_03385	COG2188	Transcriptional regulator
FOW48_03390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOW48_03390	COG1263	PTS System
FOW48_03395	COG0366	Alpha amylase catalytic
FOW48_03410	COG0697	spore germination
FOW48_03415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOW48_03420	COG1115	amino acid carrier protein
FOW48_03425	COG1126	abc transporter atp-binding protein
FOW48_03430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOW48_03435	COG0765	amino acid transport
FOW48_03440	COG0765	amino acid transport
FOW48_03445	COG0833	amino acid
FOW48_03460	COG1595	DNA-templated transcription, initiation
FOW48_03470	COG2378	regulation of single-species biofilm formation
FOW48_03475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOW48_03480	COG5002	protein histidine kinase activity
FOW48_03495	COG0659	secondary active sulfate transmembrane transporter activity
FOW48_03510	COG0747	negative chemotaxis
FOW48_03520	COG0601	transmembrane transport
FOW48_03525	COG4608	Belongs to the ABC transporter superfamily
FOW48_03535	COG2271	Major facilitator Superfamily
FOW48_03540	COG1846	Transcriptional regulator
FOW48_03545	COG0477	Major facilitator Superfamily
FOW48_03550	COG1609	Transcriptional regulator
FOW48_03555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOW48_03565	COG1129	ABC transporter
FOW48_03570	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOW48_03575	COG1879	ABC-type sugar transport system periplasmic component
FOW48_03580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOW48_03595	COG1063	alcohol dehydrogenase
FOW48_03610	COG3568	Endonuclease Exonuclease Phosphatase
FOW48_03640	COG0840	transmembrane signaling receptor activity
FOW48_03645	COG3584	3D domain protein
FOW48_03645	COG3583	domain protein
FOW48_03650	COG1476	TRANSCRIPTIONal
FOW48_03670	COG3104	oligopeptide transport
FOW48_03675	COG1114	Component of the transport system for branched-chain amino acids
FOW48_03690	COG1113	amino acid transport
FOW48_03695	COG2252	PERMEase
FOW48_03710	COG2153	protein acetylation
FOW48_03720	COG0569	domain protein
FOW48_03720	COG0475	glutathione-regulated potassium exporter activity
FOW48_03735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOW48_03740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOW48_03750	COG4990	cell redox homeostasis
FOW48_03765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOW48_03770	COG0697	spore germination
FOW48_03775	COG0531	amino acid
FOW48_03785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOW48_03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOW48_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOW48_03795	COG1918	ferrous iron import across plasma membrane
FOW48_03800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOW48_03805	COG0573	inorganic phosphate transmembrane transporter activity
FOW48_03810	COG0581	inorganic phosphate transmembrane transporter activity
FOW48_03815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOW48_03935	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOW48_03955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOW48_03960	COG1116	anion transmembrane transporter activity
FOW48_03965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOW48_03970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOW48_03975	COG0352	thiamine-phosphate diphosphorylase activity
FOW48_03980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOW48_03985	COG2104	thiamine diphosphate biosynthetic process
FOW48_03995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOW48_04000	COG0351	phosphomethylpyrimidine kinase
FOW48_04040	COG2205	protein histidine kinase activity
FOW48_04045	COG2814	Major facilitator Superfamily
FOW48_04050	COG1846	Transcriptional regulator
FOW48_04075	COG1136	(ABC) transporter
FOW48_04085	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOW48_04090	COG1129	ABC transporter
FOW48_04100	COG2252	PERMEase
FOW48_04105	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_04120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOW48_04135	COG1609	Transcriptional regulator
FOW48_04145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOW48_04185	COG0778	Nitroreductase
FOW48_04190	COG2719	SpoVR family
FOW48_04200	COG0433	COG0433 Predicted ATPase
FOW48_04220	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOW48_04225	COG1937	Protein conserved in bacteria
FOW48_04230	COG0425	Belongs to the sulfur carrier protein TusA family
FOW48_04230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOW48_04235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOW48_04235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOW48_04240	COG0425	Belongs to the sulfur carrier protein TusA family
FOW48_04245	COG0425	Belongs to the sulfur carrier protein TusA family
FOW48_04255	COG0425	Belongs to the sulfur carrier protein TusA family
FOW48_04255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOW48_04265	COG2210	Belongs to the sulfur carrier protein TusA family
FOW48_04270	COG0730	response to heat
FOW48_04285	COG0604	alcohol dehydrogenase
FOW48_04290	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOW48_04310	COG3711	transcriptional antiterminator
FOW48_04310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOW48_04315	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOW48_04320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOW48_04355	COG1136	(ABC) transporter
FOW48_04365	COG5522	Integral membrane protein (intg_mem_TP0381)
FOW48_04380	COG1114	Component of the transport system for branched-chain amino acids
FOW48_04385	COG3546	catalase activity
FOW48_04420	COG0586	Pfam SNARE associated Golgi protein
FOW48_04450	COG0531	amino acid
FOW48_04455	COG0475	glutathione-regulated potassium exporter activity
FOW48_04465	COG1737	Transcriptional regulator
FOW48_04475	COG1263	PTS System
FOW48_04475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOW48_04485	COG2259	Doxx family
FOW48_04505	COG1522	sequence-specific DNA binding
FOW48_04515	COG2076	Multidrug Resistance protein
FOW48_04520	COG2076	Multidrug Resistance protein
FOW48_04525	COG1309	transcriptional regulator
FOW48_04530	COG2814	Major facilitator Superfamily
FOW48_04535	COG1733	regulation of RNA biosynthetic process
FOW48_04545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOW48_04550	COG0477	Major facilitator Superfamily
FOW48_04570	COG2124	cytochrome p450
FOW48_04580	COG1063	alcohol dehydrogenase
FOW48_04595	COG1309	transcriptional regulator
FOW48_04600	COG1683	Conserved Protein
FOW48_04610	COG0393	Putative heavy-metal-binding
FOW48_04625	COG3344	reverse transcriptase
FOW48_04635	COG1733	regulation of RNA biosynthetic process
FOW48_04645	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOW48_04650	COG4533	DNA binding
FOW48_04655	COG2211	Major facilitator Superfamily
FOW48_04665	COG0693	protein deglycase activity
FOW48_04675	COG0531	amino acid
FOW48_04680	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOW48_04685	COG1012	belongs to the aldehyde dehydrogenase family
FOW48_04700	COG1132	(ABC) transporter
FOW48_04705	COG1132	(ABC) transporter
FOW48_04715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOW48_04720	COG0765	amino acid transport
FOW48_04725	COG1126	abc transporter atp-binding protein
FOW48_04740	COG0189	ligase activity
FOW48_04770	COG0028	Belongs to the TPP enzyme family
FOW48_04775	COG3527	Alpha-acetolactate decarboxylase
FOW48_04785	COG0561	phosphatase activity
FOW48_04790	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOW48_04790	COG3409	Peptidoglycan-binding domain 1 protein
FOW48_04795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOW48_04810	COG3344	reverse transcriptase
FOW48_04825	COG0659	secondary active sulfate transmembrane transporter activity
FOW48_04840	COG0653	protein targeting
FOW48_04845	COG2244	polysaccharide biosynthetic process
FOW48_04855	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOW48_04860	COG4196	transglutaminase domain protein
FOW48_04875	COG1696	Membrane protein involved in D-alanine export
FOW48_04890	COG1024	Enoyl-CoA hydratase
FOW48_04925	COG1363	Peptidase, m42
FOW48_04980	COG0477	Major facilitator Superfamily
FOW48_04985	COG3290	protein histidine kinase activity
FOW48_04990	COG4565	transcriptional regulatory protein
FOW48_04995	COG3181	Tripartite tricarboxylate transporter family receptor
FOW48_05070	COG0789	Transcriptional regulator
FOW48_05070	COG4978	Transcriptional regulator
FOW48_05085	COG0305	Participates in initiation and elongation during chromosome replication
FOW48_05105	COG0477	Major facilitator Superfamily
FOW48_05180	COG1183	phosphatidylcholine synthase activity
FOW48_05195	COG2376	Dihydroxyacetone kinase
FOW48_05210	COG2376	Dihydroxyacetone kinase
FOW48_05235	COG2770	Histidine kinase
FOW48_05235	COG3437	response regulator, receiver
FOW48_05320	COG3237	CsbD-like
FOW48_05345	COG1191	sigma factor activity
FOW48_05355	COG2208	phosphoserine phosphatase activity
FOW48_05360	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOW48_05365	COG0784	Response regulator, receiver
FOW48_05365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOW48_05365	COG2198	Histidine kinase
FOW48_05365	COG2205	protein histidine kinase activity
FOW48_05385	COG0393	Putative heavy-metal-binding
FOW48_05425	COG0420	3'-5' exonuclease activity
FOW48_05430	COG4717	serine-type aminopeptidase activity
FOW48_05440	COG1309	transcriptional regulator
FOW48_05445	COG2814	Major facilitator Superfamily
FOW48_05450	COG0346	lactoylglutathione lyase activity
FOW48_05455	COG0346	lactoylglutathione lyase activity
FOW48_05460	COG0346	lactoylglutathione lyase activity
FOW48_05470	COG2267	carboxylic ester hydrolase activity
FOW48_05500	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOW48_05505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOW48_05515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOW48_05525	COG1595	DNA-templated transcription, initiation
FOW48_05535	COG0772	Belongs to the SEDS family
FOW48_05545	COG3973	AAA domain
FOW48_05570	COG4980	gas vesicle protein
FOW48_05575	COG0537	adenosine 5'-monophosphoramidase activity
FOW48_05580	COG1131	(ABC) transporter
FOW48_05585	COG4473	ABC transporter
FOW48_05600	COG1309	transcriptional regulator
FOW48_05605	COG3402	PFAM membrane-flanked domain
FOW48_05610	COG3428	Bacterial PH domain
FOW48_05640	COG3402	PFAM membrane-flanked domain
FOW48_05645	COG3428	Bacterial PH domain
FOW48_05650	COG2329	Antibiotic biosynthesis monooxygenase
FOW48_05695	COG1309	transcriptional regulator
FOW48_05700	COG1511	domain protein
FOW48_05730	COG2378	regulation of single-species biofilm formation
FOW48_05740	COG1609	Transcriptional regulator
FOW48_05750	COG1234	tRNA 3'-trailer cleavage
FOW48_05755	COG0095	Lipoate-protein ligase
FOW48_05765	COG0318	PFAM AMP-dependent synthetase and ligase
FOW48_05780	COG3209	COG3209 Rhs family protein
FOW48_05840	COG1309	transcriptional regulator
FOW48_05845	COG1073	alpha beta
FOW48_05850	COG1408	metallophosphoesterase
FOW48_05860	COG1078	dGTPase activity
FOW48_05870	COG1595	DNA-templated transcription, initiation
FOW48_05880	COG2207	Transcriptional regulator
FOW48_05880	COG3708	Transcriptional regulator
FOW48_05890	COG2205	protein histidine kinase activity
FOW48_05895	COG0745	RESPONSE REGULATOR receiver
FOW48_05920	COG0501	Belongs to the peptidase M48B family
FOW48_05925	COG0697	spore germination
FOW48_05940	COG0497	DNA recombination
FOW48_05945	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOW48_05950	COG2224	Isocitrate lyase
FOW48_05965	COG1278	Cold shock
FOW48_05980	COG4903	ComK protein
FOW48_05990	COG0398	Pfam SNARE associated Golgi protein
FOW48_06050	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOW48_06075	COG0367	asparagine synthase
FOW48_06085	COG0753	catalase activity
FOW48_06090	COG0004	ammonium transporteR
FOW48_06115	COG2996	Protein conserved in bacteria
FOW48_06120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOW48_06130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOW48_06145	COG0561	phosphatase activity
FOW48_06165	COG2267	carboxylic ester hydrolase activity
FOW48_06180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOW48_06185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOW48_06190	COG5504	Zn-dependent protease
FOW48_06200	COG0180	Tryptophanyl-tRNA synthetase
FOW48_06215	COG4166	transmembrane transport
FOW48_06220	COG0601	transmembrane transport
FOW48_06225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOW48_06230	COG0444	Belongs to the ABC transporter superfamily
FOW48_06235	COG4608	Belongs to the ABC transporter superfamily
FOW48_06240	COG0534	Mate efflux family protein
FOW48_06245	COG4166	transmembrane transport
FOW48_06255	COG1393	Belongs to the ArsC family
FOW48_06260	COG0861	Integral membrane protein TerC family
FOW48_06265	COG4862	establishment of competence for transformation
FOW48_06270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOW48_06280	COG1164	Oligoendopeptidase f
FOW48_06290	COG2346	COG2346, Truncated hemoglobins
FOW48_06295	COG4116	CYTH
FOW48_06305	COG2357	RelA SpoT domain protein
FOW48_06315	COG0564	pseudouridine synthase activity
FOW48_06330	COG0772	Belongs to the SEDS family
FOW48_06335	COG1216	Glycosyl transferase, family 2
FOW48_06355	COG0457	Tetratricopeptide repeat
FOW48_06355	COG0463	Glycosyl transferase, family 2
FOW48_06375	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOW48_06390	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOW48_06435	COG2153	protein acetylation
FOW48_06445	COG2382	esterase
FOW48_06460	COG5492	domain, Protein
FOW48_06465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOW48_06480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOW48_06480	COG0512	Glutamine amidotransferase of anthranilate synthase
FOW48_06515	COG1620	l-lactate permease
FOW48_06520	COG5634	Uncharacterized conserved protein (DUF2278)
FOW48_06605	COG1476	TRANSCRIPTIONal
FOW48_06660	COG1686	Belongs to the peptidase S11 family
FOW48_06665	COG0681	Belongs to the peptidase S26 family
FOW48_06700	COG1012	belongs to the aldehyde dehydrogenase family
FOW48_06710	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOW48_06715	COG1177	transmembrane transport
FOW48_06720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOW48_06730	COG2409	Drug exporters of the RND superfamily
FOW48_06740	COG0564	pseudouridine synthase activity
FOW48_06750	COG2340	Cysteine-rich secretory protein family
FOW48_06755	COG0247	lactate metabolic process
FOW48_06760	COG0277	FAD linked oxidase domain protein
FOW48_06765	COG3835	regulator
FOW48_06775	COG0745	RESPONSE REGULATOR receiver
FOW48_06780	COG5002	protein histidine kinase activity
FOW48_06785	COG2186	Transcriptional regulator
FOW48_06805	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOW48_06815	COG2116	formate transmembrane transporter activity
FOW48_06820	COG0861	Integral membrane protein TerC family
FOW48_06835	COG2030	dehydratase
FOW48_06855	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_06860	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOW48_06870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOW48_06885	COG1840	ABC-type Fe3 transport system, periplasmic component
FOW48_06890	COG3842	ATPase activity
FOW48_06915	COG1349	DNA-binding transcription factor activity
FOW48_06925	COG0235	Class ii aldolase
FOW48_06935	COG2861	carbohydrate metabolic process
FOW48_06945	COG3852	Histidine kinase
FOW48_06950	COG1846	Transcriptional regulator
FOW48_06960	COG2318	DinB family
FOW48_06970	COG5002	protein histidine kinase activity
FOW48_06980	COG0720	synthase
FOW48_06995	COG4873	Protein conserved in bacteria
FOW48_07030	COG1780	Probably involved in ribonucleotide reductase function
FOW48_07055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOW48_07060	COG1725	Transcriptional regulator
FOW48_07065	COG1131	(ABC) transporter
FOW48_07075	COG1131	(ABC) transporter
FOW48_07080	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOW48_07085	COG1266	CAAX protease self-immunity
FOW48_07095	COG1522	sequence-specific DNA binding
FOW48_07105	COG1335	isochorismatase
FOW48_07115	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOW48_07120	COG2070	2-Nitropropane dioxygenase
FOW48_07125	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOW48_07135	COG1696	Membrane protein involved in D-alanine export
FOW48_07155	COG0716	FMN binding
FOW48_07165	COG3173	Aminoglycoside phosphotransferase
FOW48_07180	COG0534	Mate efflux family protein
FOW48_07200	COG1846	Transcriptional regulator
FOW48_07210	COG1301	dicarboxylic acid transport
FOW48_07215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOW48_07220	COG4709	membrane
FOW48_07225	COG3874	Sporulation protein YtfJ
FOW48_07245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOW48_07250	COG0028	Belongs to the TPP enzyme family
FOW48_07255	COG0440	acetolactate synthase activity
FOW48_07330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOW48_07345	COG1183	phosphatidylcholine synthase activity
FOW48_07350	COG1368	sulfuric ester hydrolase activity
FOW48_07360	COG0019	diaminopimelate decarboxylase activity
FOW48_07380	COG0529	Catalyzes the synthesis of activated sulfate
FOW48_07385	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOW48_07405	COG1648	precorrin-2 dehydrogenase activity
FOW48_07410	COG0733	neurotransmitter:sodium symporter activity
FOW48_07430	COG1757	Na H antiporter
FOW48_07445	COG4758	membrane
FOW48_07450	COG4585	Histidine kinase
FOW48_07455	COG2197	response regulator
FOW48_07465	COG1114	Component of the transport system for branched-chain amino acids
FOW48_07475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOW48_07515	COG0730	response to heat
FOW48_07520	COG0306	phosphate transporter
FOW48_07525	COG1392	Phosphate transport regulator
FOW48_07530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOW48_07545	COG3852	Histidine kinase
FOW48_07550	COG1801	Protein of unknown function DUF72
FOW48_07560	COG0582	viral genome integration into host DNA
FOW48_07580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOW48_07580	COG0392	lysyltransferase activity
FOW48_07595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOW48_07600	COG1686	Belongs to the peptidase S11 family
FOW48_07605	COG2715	membrane protein required for spore maturation
FOW48_07610	COG0700	Nucleoside recognition
FOW48_07615	COG1187	pseudouridine synthase activity
FOW48_07625	COG1333	cytochrome c biogenesis protein
FOW48_07630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOW48_07635	COG0745	RESPONSE REGULATOR receiver
FOW48_07645	COG2096	Adenosyltransferase
FOW48_07650	COG4942	peptidase
FOW48_07660	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOW48_07665	COG1141	Ferredoxin
FOW48_07675	COG0514	ATP-dependent DNA helicase (RecQ)
FOW48_07680	COG1266	CAAX protease self-immunity
FOW48_07690	COG1408	metallophosphoesterase
FOW48_07700	COG4862	establishment of competence for transformation
FOW48_07705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOW48_07725	COG0492	ferredoxin-NADP+ reductase activity
FOW48_07795	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOW48_07810	COG0142	geranyltranstransferase activity
FOW48_07820	COG0142	geranyltranstransferase activity
FOW48_07825	COG0105	UTP biosynthetic process
FOW48_07840	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOW48_07850	COG0457	Tetratricopeptide repeat
FOW48_07870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOW48_07875	COG2010	Cytochrome c
FOW48_07875	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOW48_07885	COG4347	Protein of unknown function (DUF1405)
FOW48_07900	COG2738	Putative neutral zinc metallopeptidase
FOW48_07910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOW48_07915	COG1694	Mazg nucleotide pyrophosphohydrolase
FOW48_07930	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOW48_07935	COG0438	transferase activity, transferring glycosyl groups
FOW48_07970	COG1199	ATP-dependent helicase activity
FOW48_07970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOW48_07990	COG3935	DnaD domain protein
FOW48_07995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOW48_08005	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOW48_08005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOW48_08060	COG0116	Belongs to the methyltransferase superfamily
FOW48_08070	COG1199	ATP-dependent helicase activity
FOW48_08085	COG0024	Methionine aminopeptidase
FOW48_08095	COG2233	PERMEase
FOW48_08100	COG2311	Membrane
FOW48_08105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOW48_08115	COG0456	acetyltransferase
FOW48_08150	COG0754	glutathionylspermidine amidase activity
FOW48_08165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOW48_08210	COG0328	RNA-DNA hybrid ribonuclease activity
FOW48_08245	COG3403	YqcI/YcgG family
FOW48_08250	COG1280	lysine exporter protein (LysE YggA)
FOW48_08265	COG3162	membrane
FOW48_08270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOW48_08275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOW48_08285	COG0475	glutathione-regulated potassium exporter activity
FOW48_08290	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOW48_08295	COG0789	Transcriptional regulator
FOW48_08295	COG4978	Transcriptional regulator
FOW48_08310	COG2323	membrane
FOW48_08315	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOW48_08350	COG2814	Major facilitator Superfamily
FOW48_08380	COG1923	regulation of RNA biosynthetic process
FOW48_08390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOW48_08395	COG1360	Flagellar Motor Protein
FOW48_08400	COG2201	protein-glutamate methylesterase activity
FOW48_08405	COG0643	Histidine kinase
FOW48_08405	COG2198	Histidine kinase
FOW48_08410	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOW48_08410	COG1776	CheC inhibitor of MCP methylation
FOW48_08425	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOW48_08445	COG1256	bacterial-type flagellum assembly
FOW48_08450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOW48_08455	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOW48_08470	COG1815	bacterial-type flagellum-dependent cell motility
FOW48_08475	COG1558	bacterial-type flagellum-dependent cell motility
FOW48_08480	COG1677	Flagellar hook-basal body complex protein FliE
FOW48_08485	COG1766	The M ring may be actively involved in energy transduction
FOW48_08490	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOW48_08500	COG1157	protein secretion by the type III secretion system
FOW48_08535	COG0835	chemotaxis
FOW48_08535	COG0784	Response regulator, receiver
FOW48_08550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOW48_08555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOW48_08560	COG0741	lytic transglycosylase activity
FOW48_08570	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOW48_08575	COG1776	CheC inhibitor of MCP methylation
FOW48_08575	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOW48_08585	COG1338	Plays a role in the flagellum-specific transport system
FOW48_08590	COG1987	bacterial-type flagellum assembly
FOW48_08605	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOW48_08610	COG1419	protein localization to endoplasmic reticulum
FOW48_08615	COG4786	Flagellar basal body rod
FOW48_08620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOW48_08655	COG2329	Antibiotic biosynthesis monooxygenase
FOW48_08670	COG3764	Sortase (surface protein transpeptidase)
FOW48_08675	COG3764	Sortase (surface protein transpeptidase)
FOW48_08705	COG3842	ATPase activity
FOW48_08720	COG1234	tRNA 3'-trailer cleavage
FOW48_08735	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_08750	COG1686	Belongs to the peptidase S11 family
FOW48_08760	COG0406	alpha-ribazole phosphatase activity
FOW48_08780	COG1846	Transcriptional regulator
FOW48_08790	COG0367	asparagine synthase
FOW48_08795	COG3344	reverse transcriptase
FOW48_08800	COG0367	asparagine synthase
FOW48_08835	COG0697	spore germination
FOW48_08840	COG0438	transferase activity, transferring glycosyl groups
FOW48_08840	COG1216	Glycosyl transferase, family 2
FOW48_08845	COG1757	Na H antiporter
FOW48_08850	COG0114	fumarate hydratase activity
FOW48_08870	COG0534	Mate efflux family protein
FOW48_08875	COG3340	Belongs to the peptidase S51 family
FOW48_08915	COG2733	membrane
FOW48_08955	COG1131	(ABC) transporter
FOW48_08970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOW48_08975	COG0528	UMP kinase activity
FOW48_08985	COG1027	Aspartate ammonia-lyase
FOW48_08990	COG0281	malic enzyme
FOW48_08995	COG4191	Histidine kinase
FOW48_09000	COG0784	Response regulator, receiver
FOW48_09005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOW48_09105	COG1966	Carbon starvation protein
FOW48_09115	COG1695	Transcriptional regulator
FOW48_09125	COG0477	Major facilitator Superfamily
FOW48_09130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOW48_09140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOW48_09145	COG4166	transmembrane transport
FOW48_09150	COG2223	nitrite transmembrane transporter activity
FOW48_09155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOW48_09170	COG2244	polysaccharide biosynthetic process
FOW48_09175	COG0733	neurotransmitter:sodium symporter activity
FOW48_09185	COG5566	PFAM Mor transcription activator
FOW48_09190	COG2323	membrane
FOW48_09205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOW48_09210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOW48_09215	COG0028	Belongs to the TPP enzyme family
FOW48_09220	COG0440	acetolactate synthase activity
FOW48_09225	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOW48_09235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOW48_09260	COG2814	Major facilitator Superfamily
FOW48_09265	COG3384	dioxygenase
FOW48_09275	COG3279	Response regulator of the LytR AlgR family
FOW48_09280	COG0427	acetyl-CoA hydrolase
FOW48_09310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOW48_09315	COG0745	RESPONSE REGULATOR receiver
FOW48_09330	COG1914	H( )-stimulated, divalent metal cation uptake system
FOW48_09345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOW48_09370	COG0457	Tetratricopeptide repeat
FOW48_09380	COG2390	Transcriptional regulator
FOW48_09405	COG4846	Membrane protein involved in cytochrome C biogenesis
FOW48_09415	COG0006	proline dipeptidase activity
FOW48_09450	COG1114	Component of the transport system for branched-chain amino acids
FOW48_09465	COG2372	response to copper ion
FOW48_09465	COG1276	copper resistance
FOW48_09470	COG4549	nuclear export factor GLE1
FOW48_09475	COG0697	spore germination
FOW48_09480	COG0583	DNA-binding transcription factor activity
FOW48_09485	COG1959	2 iron, 2 sulfur cluster binding
FOW48_09490	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOW48_09495	COG0778	Nitroreductase
FOW48_09505	COG0628	permease
FOW48_09510	COG0039	L-malate dehydrogenase activity
FOW48_09515	COG1231	oxidoreductase activity
FOW48_09520	COG0523	cobalamin synthesis protein
FOW48_09530	COG0411	ABC transporter
FOW48_09550	COG0583	DNA-binding transcription factor activity
FOW48_09560	COG1942	4-Oxalocrotonate Tautomerase
FOW48_09580	COG1271	oxidase subunit
FOW48_09585	COG1294	oxidase, subunit
FOW48_09590	COG4988	ABC transporter
FOW48_09595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOW48_09640	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOW48_09645	COG1686	Belongs to the peptidase S11 family
FOW48_09660	COG1388	LysM domain
FOW48_09660	COG0791	NLP P60 protein
FOW48_09675	COG0745	RESPONSE REGULATOR receiver
FOW48_09680	COG5002	protein histidine kinase activity
FOW48_09690	COG0300	oxidoreductase activity
FOW48_09705	COG0726	polysaccharide deacetylase
FOW48_09725	COG0460	homoserine dehydrogenase
FOW48_09750	COG1316	TRANSCRIPTIONal
FOW48_09760	COG0726	polysaccharide deacetylase
FOW48_09770	COG1285	pathogenesis
FOW48_09775	COG1247	-acetyltransferase
FOW48_09790	COG1279	arginine transmembrane transporter activity
FOW48_09805	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOW48_09840	COG0577	efflux transmembrane transporter activity
FOW48_09845	COG2002	toxin-antitoxin pair type II binding
FOW48_09850	COG1404	Belongs to the peptidase S8 family
FOW48_09855	COG3842	ATPase activity
FOW48_09860	COG2508	Transcriptional regulator
FOW48_09880	COG0395	ABC-type sugar transport system, permease component
FOW48_09885	COG5426	von Willebrand factor, type A
FOW48_09890	COG1940	carbohydrate kinase activity
FOW48_09895	COG2222	sugar isomerase
FOW48_09905	COG1105	Belongs to the carbohydrate kinase PfkB family
FOW48_09925	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FOW48_09930	COG0640	Transcriptional regulator
FOW48_09935	COG0667	Aldo Keto reductase
FOW48_09940	COG2814	Major facilitator Superfamily
FOW48_09965	COG0840	transmembrane signaling receptor activity
FOW48_09980	COG3949	Membrane
FOW48_09985	COG0783	Belongs to the Dps family
FOW48_10000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOW48_10010	COG1231	oxidoreductase activity
FOW48_10020	COG4989	oxidoreductase activity
FOW48_10025	COG0523	cobalamin synthesis protein
FOW48_10030	COG0456	acetyltransferase
FOW48_10035	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOW48_10035	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOW48_10040	COG0702	epimerase
FOW48_10050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOW48_10060	COG4166	transmembrane transport
FOW48_10075	COG0406	alpha-ribazole phosphatase activity
FOW48_10090	COG1051	belongs to the nudix hydrolase family
FOW48_10095	COG0586	Pfam SNARE associated Golgi protein
FOW48_10100	COG2244	polysaccharide biosynthetic process
FOW48_10110	COG0701	Predicted permease
FOW48_10120	COG1607	acyl-coa hydrolase
FOW48_10130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOW48_10145	COG0702	epimerase
FOW48_10150	COG2839	Protein conserved in bacteria
FOW48_10155	COG1253	flavin adenine dinucleotide binding
FOW48_10170	COG1114	Component of the transport system for branched-chain amino acids
FOW48_10175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOW48_10195	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOW48_10205	COG1876	peptidase activity
FOW48_10215	COG0154	amidase activity
FOW48_10220	COG2211	Major facilitator Superfamily
FOW48_10240	COG0561	phosphatase activity
FOW48_10250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOW48_10270	COG1819	glycosyl
FOW48_10275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOW48_10280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOW48_10310	COG0456	acetyltransferase
FOW48_10335	COG3874	Sporulation protein YtfJ
FOW48_10360	COG2226	methyltransferase
FOW48_10380	COG0346	lactoylglutathione lyase activity
FOW48_10395	COG3620	sequence-specific DNA binding
FOW48_10425	COG2002	toxin-antitoxin pair type II binding
FOW48_10500	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOW48_10505	COG0582	viral genome integration into host DNA
FOW48_10550	COG0740	serine-type endopeptidase activity
FOW48_10705	COG0426	domain, Protein
FOW48_10705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOW48_10715	COG0386	Belongs to the glutathione peroxidase family
FOW48_10720	COG1305	Transglutaminase-like
FOW48_10725	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOW48_10735	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOW48_10740	COG1140	nitrate reductase beta subunit
FOW48_10745	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOW48_10750	COG2181	nitrate reductase activity
FOW48_10755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOW48_10760	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOW48_10765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOW48_10770	COG0303	'Molybdopterin
FOW48_10775	COG0314	molybdopterin synthase activity
FOW48_10785	COG2223	nitrite transmembrane transporter activity
FOW48_10805	COG1648	precorrin-2 dehydrogenase activity
FOW48_10815	COG1587	Uroporphyrinogen-III synthase
FOW48_10815	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOW48_10820	COG2146	nitrite reductase [NAD(P)H] activity
FOW48_10825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOW48_10830	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOW48_10865	COG2359	stage V sporulation protein S
FOW48_10885	COG1418	mRNA catabolic process
FOW48_10905	COG0629	single-stranded DNA binding
FOW48_10920	COG1413	lyase activity
FOW48_10935	COG2136	Putative SAM-dependent methyltransferase
FOW48_10935	COG2521	methyltransferase
FOW48_10985	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOW48_10990	COG0017	Asparaginyl-tRNA synthetase
FOW48_11020	COG2610	gluconate transmembrane transporter activity
FOW48_11025	COG1454	alcohol dehydrogenase
FOW48_11030	COG1794	racemase activity, acting on amino acids and derivatives
FOW48_11040	COG0456	acetyltransferase
FOW48_11045	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOW48_11055	COG1131	(ABC) transporter
FOW48_11060	COG4473	ABC transporter
FOW48_11070	COG0546	phosphoglycolate phosphatase activity
FOW48_11085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOW48_11115	COG0204	Acyl-transferase
FOW48_11120	COG1272	protein, Hemolysin III
FOW48_11130	COG0805	protein transport
FOW48_11140	COG1307	EDD domain protein, DegV family
FOW48_11145	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOW48_11150	COG1999	signal sequence binding
FOW48_11155	COG0071	Belongs to the small heat shock protein (HSP20) family
FOW48_11160	COG0367	asparagine synthase
FOW48_11180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOW48_11200	COG1335	isochorismatase
FOW48_11205	COG1051	belongs to the nudix hydrolase family
FOW48_11215	COG0668	transmembrane transport
FOW48_11220	COG2203	Gaf domain
FOW48_11220	COG4585	Histidine kinase
FOW48_11225	COG2197	response regulator
FOW48_11230	COG1737	Transcriptional regulator
FOW48_11235	COG1737	Transcriptional regulator
FOW48_11240	COG1064	alcohol dehydrogenase
FOW48_11335	COG1253	flavin adenine dinucleotide binding
FOW48_11340	COG1012	belongs to the aldehyde dehydrogenase family
FOW48_11345	COG5506	Protein of unknown function (DUF1694)
FOW48_11360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOW48_11365	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOW48_11370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOW48_11375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOW48_11380	COG0456	acetyltransferase
FOW48_11385	COG3829	transcription factor binding
FOW48_11390	COG1509	lysine 2,3-aminomutase activity
FOW48_11425	COG4326	sporulation control protein
FOW48_11430	COG0671	phosphoesterase, PA-phosphatase related
FOW48_11435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOW48_11440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOW48_11450	COG5484	DNA packaging
FOW48_11450	COG3728	DNA packaging
FOW48_11485	COG1595	DNA-templated transcription, initiation
FOW48_11520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOW48_11575	COG2814	Major facilitator Superfamily
FOW48_11580	COG4841	protein insertion into membrane
FOW48_11585	COG0372	Belongs to the citrate synthase family
FOW48_11590	COG2079	MmgE PrpD family protein
FOW48_11595	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOW48_11600	COG1960	acyl-CoA dehydrogenase activity
FOW48_11605	COG2084	Dehydrogenase
FOW48_11615	COG1280	lysine exporter protein (LysE YggA)
FOW48_11620	COG1024	Enoyl-CoA hydratase
FOW48_11660	COG2223	nitrite transmembrane transporter activity
FOW48_11670	COG1169	isochorismate synthase
FOW48_11675	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOW48_11680	COG3433	isochorismatase activity
FOW48_11680	COG1535	isochorismatase
FOW48_11685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOW48_11695	COG2814	Major facilitator Superfamily
FOW48_11710	COG0776	regulation of translation
FOW48_11720	COG2318	DinB family
FOW48_11755	COG2329	Antibiotic biosynthesis monooxygenase
FOW48_11760	COG1187	pseudouridine synthase activity
FOW48_11770	COG1136	(ABC) transporter
FOW48_11780	COG2814	Major facilitator Superfamily
FOW48_11795	COG0028	Belongs to the TPP enzyme family
FOW48_11805	COG2226	methyltransferase
FOW48_11875	COG1247	-acetyltransferase
FOW48_11895	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FOW48_11910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOW48_11920	COG1278	Cold shock
FOW48_11935	COG0010	Belongs to the arginase family
FOW48_11940	COG0561	phosphatase activity
FOW48_11955	COG2814	Major facilitator Superfamily
FOW48_11960	COG0583	DNA-binding transcription factor activity
FOW48_11965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOW48_11980	COG0583	DNA-binding transcription factor activity
FOW48_11985	COG2258	MOSC domain
FOW48_12000	COG1132	(ABC) transporter
FOW48_12005	COG1132	(ABC) transporter
FOW48_12025	COG1396	sequence-specific DNA binding
FOW48_12070	COG1595	DNA-templated transcription, initiation
FOW48_12090	COG1649	PFAM Uncharacterised BCR, COG1649
FOW48_12115	COG2971	BadF BadG BcrA BcrD
FOW48_12150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOW48_12200	COG0577	efflux transmembrane transporter activity
FOW48_12200	COG1136	(ABC) transporter
FOW48_12205	COG3615	Tellurite resistance protein tehB
FOW48_12205	COG0500	methyltransferase
FOW48_12260	COG1595	DNA-templated transcription, initiation
FOW48_12280	COG2367	Beta-lactamase
FOW48_12285	COG1408	metallophosphoesterase
FOW48_12295	COG1131	(ABC) transporter
FOW48_12320	COG1960	acyl-CoA dehydrogenase activity
FOW48_12325	COG0439	Biotin carboxylase
FOW48_12330	COG0511	ligase activity, forming carbon-carbon bonds
FOW48_12335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOW48_12340	COG1024	Enoyl-CoA hydratase
FOW48_12345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOW48_12350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOW48_12365	COG0572	uridine kinase
FOW48_12370	COG2318	DinB family
FOW48_12375	COG1686	Belongs to the peptidase S11 family
FOW48_12420	COG3227	Zinc metalloprotease (Elastase)
FOW48_12455	COG2814	Major facilitator Superfamily
FOW48_12495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOW48_12510	COG1063	alcohol dehydrogenase
FOW48_12515	COG2323	membrane
FOW48_12520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOW48_12535	COG3386	PFAM SMP-30 Gluconolaconase
FOW48_12545	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FOW48_12550	COG3773	Cell wall hydrolase
FOW48_12560	COG0745	RESPONSE REGULATOR receiver
FOW48_12585	COG1136	(ABC) transporter
FOW48_12590	COG0577	efflux transmembrane transporter activity
FOW48_12610	COG0460	homoserine dehydrogenase
FOW48_12615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOW48_12625	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOW48_12715	COG5444	nuclease activity
FOW48_12760	COG2124	cytochrome p450
FOW48_12795	COG5002	protein histidine kinase activity
FOW48_12810	COG1794	racemase activity, acting on amino acids and derivatives
FOW48_12835	COG2205	protein histidine kinase activity
FOW48_12850	COG0604	alcohol dehydrogenase
FOW48_12855	COG0671	phosphoesterase, PA-phosphatase related
FOW48_12870	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_12935	COG0584	glycerophosphoryl diester phosphodiesterase
FOW48_12955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOW48_12960	COG0697	spore germination
FOW48_12970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOW48_13005	COG2816	NAD+ diphosphatase activity
FOW48_13010	COG0592	DNA-directed DNA polymerase activity
FOW48_13015	COG1051	belongs to the nudix hydrolase family
FOW48_13050	COG3878	Protein conserved in bacteria
FOW48_13115	COG0322	excinuclease ABC activity
FOW48_13150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOW48_13195	COG1523	belongs to the glycosyl hydrolase 13 family
FOW48_13210	COG0346	lactoylglutathione lyase activity
FOW48_13215	COG0201	protein transport
FOW48_13255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOW48_13275	COG3773	Cell wall hydrolase
FOW48_13275	COG3409	Peptidoglycan-binding domain 1 protein
FOW48_13310	COG1309	transcriptional regulator
FOW48_13345	COG3284	Transcriptional regulator
FOW48_13360	COG1349	DNA-binding transcription factor activity
FOW48_13375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOW48_13380	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOW48_13385	COG0022	dehydrogenase e1 component
FOW48_13390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOW48_13405	COG0456	acetyltransferase
FOW48_13405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOW48_13445	COG4176	ABC-type proline glycine betaine transport system permease component
FOW48_13450	COG0517	IMP dehydrogenase activity
FOW48_13450	COG4175	Glycine betaine
FOW48_13475	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOW48_13480	COG2153	protein acetylation
FOW48_13485	COG3397	chitin binding
FOW48_13490	COG1819	glycosyl
FOW48_13505	COG2205	protein histidine kinase activity
FOW48_13510	COG2226	methyltransferase
FOW48_13515	COG2315	Protein conserved in bacteria
FOW48_13525	COG0658	competence protein
FOW48_13525	COG2333	competence protein COMEC
FOW48_13565	COG3973	AAA domain
FOW48_13585	COG0514	ATP-dependent DNA helicase (RecQ)
FOW48_13615	COG4637	Psort location Cytoplasmic, score
FOW48_13635	COG3397	chitin binding
FOW48_13655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOW48_13660	COG1115	amino acid carrier protein
FOW48_13665	COG1012	belongs to the aldehyde dehydrogenase family
FOW48_13670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOW48_13680	COG3938	Belongs to the proline racemase family
FOW48_13685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOW48_13730	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOW48_13735	COG0519	Catalyzes the synthesis of GMP from XMP
FOW48_13740	COG4166	transmembrane transport
FOW48_13750	COG4948	Mandelate Racemase Muconate Lactonizing
FOW48_13800	COG2936	dipeptidyl-peptidase activity
FOW48_13805	COG5002	protein histidine kinase activity
FOW48_13810	COG0745	RESPONSE REGULATOR receiver
FOW48_13845	COG1164	Oligoendopeptidase f
FOW48_13855	COG1307	EDD domain protein, DegV family
FOW48_14085	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOW48_14115	COG2002	toxin-antitoxin pair type II binding
FOW48_14285	COG1664	Polymer-forming cytoskeletal
FOW48_14290	COG0789	Transcriptional regulator
FOW48_14295	COG4533	DNA binding
FOW48_14300	COG0477	Major facilitator Superfamily
FOW48_14300	COG2814	Major facilitator Superfamily
FOW48_14325	COG2261	transglycosylase associated protein
FOW48_14375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOW48_14385	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOW48_14440	COG0628	permease
FOW48_14450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOW48_14455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOW48_14460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOW48_14505	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOW48_14525	COG0697	spore germination
FOW48_14550	COG4912	Dna alkylation repair
FOW48_14570	COG0726	polysaccharide deacetylase
FOW48_14580	COG0861	Integral membrane protein TerC family
FOW48_14585	COG1368	sulfuric ester hydrolase activity
FOW48_14595	COG0488	(ABC) transporter
FOW48_14605	COG1033	growth of symbiont in host cell
FOW48_14605	COG2409	Drug exporters of the RND superfamily
FOW48_14615	COG1309	transcriptional regulator
FOW48_14630	COG0287	Prephenate dehydrogenase
FOW48_14635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOW48_14645	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOW48_14645	COG1605	Chorismate mutase
FOW48_14700	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOW48_14710	COG2390	Transcriptional regulator
FOW48_14715	COG1070	Carbohydrate kinase
FOW48_14735	COG2329	Antibiotic biosynthesis monooxygenase
FOW48_14750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOW48_14765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOW48_14770	COG4187	Peptidase family M20/M25/M40
FOW48_14775	COG1414	Transcriptional regulator
FOW48_14785	COG0833	amino acid
FOW48_14790	COG1690	Belongs to the RtcB family
FOW48_14795	COG3239	Fatty acid desaturase
FOW48_14815	COG3655	Transcriptional regulator
FOW48_14830	COG4377	Putative membrane peptidase family (DUF2324)
FOW48_14840	COG3279	Response regulator of the LytR AlgR family
FOW48_14855	COG0346	lactoylglutathione lyase activity
FOW48_14875	COG0714	Associated with various cellular activities
FOW48_14895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOW48_14900	COG0753	catalase activity
FOW48_14905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOW48_14925	COG1846	Transcriptional regulator
FOW48_14930	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOW48_14955	COG0714	Associated with various cellular activities
FOW48_14965	COG0778	Nitroreductase
FOW48_14970	COG1846	Transcriptional regulator
FOW48_15010	COG1725	Transcriptional regulator
FOW48_15050	COG0456	acetyltransferase
FOW48_15065	COG0697	spore germination
FOW48_15070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOW48_15135	COG4335	DNA alkylation repair
FOW48_15210	COG1984	allophanate hydrolase subunit 2
FOW48_15215	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOW48_15220	COG1414	Transcriptional regulator
FOW48_15235	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOW48_15240	COG0640	Transcriptional regulator
FOW48_15260	COG1960	acyl-CoA dehydrogenase activity
FOW48_15300	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOW48_15315	COG0574	Belongs to the PEP-utilizing enzyme family
FOW48_15315	COG3848	Pyruvate phosphate dikinase
FOW48_15325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOW48_15340	COG5577	PFAM Coat F domain
FOW48_15345	COG3403	YqcI/YcgG family
FOW48_15350	COG1280	lysine exporter protein (LysE YggA)
FOW48_15355	COG1113	amino acid transport
FOW48_15380	COG1063	alcohol dehydrogenase
FOW48_15390	COG1027	Aspartate ammonia-lyase
FOW48_15395	COG0252	asparaginase activity
FOW48_15400	COG1396	sequence-specific DNA binding
FOW48_15405	COG2801	Transposase and inactivated derivatives
FOW48_15410	COG0322	excinuclease ABC activity
FOW48_15415	COG0531	amino acid
FOW48_15420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOW48_15430	COG0531	amino acid
FOW48_15435	COG0697	spore germination
FOW48_15445	COG0784	Response regulator, receiver
FOW48_15450	COG4191	Histidine kinase
FOW48_15455	COG2066	Belongs to the glutaminase family
FOW48_15460	COG1115	amino acid carrier protein
FOW48_15485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOW48_15485	COG0723	plastoquinol--plastocyanin reductase activity
FOW48_15500	COG0531	amino acid
FOW48_15505	COG0737	Belongs to the 5'-nucleotidase family
FOW48_15510	COG0753	catalase activity
FOW48_15515	COG0598	Magnesium transport protein CorA
FOW48_15575	COG0415	Belongs to the DNA photolyase family
FOW48_15590	COG0288	reversible hydration of carbon dioxide
FOW48_15600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOW48_15605	COG5609	conserved protein (DUF2294)
FOW48_15620	COG0697	spore germination
FOW48_15630	COG1575	Belongs to the MenA family. Type 1 subfamily
FOW48_15635	COG4641	Protein conserved in bacteria
FOW48_15660	COG3347	Dehydrogenase
FOW48_15660	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_15670	COG1070	Carbohydrate kinase
FOW48_15675	COG0235	Class ii aldolase
FOW48_15685	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOW48_15695	COG4154	Belongs to the RbsD FucU family
FOW48_15715	COG0346	lactoylglutathione lyase activity
FOW48_15720	COG0640	Transcriptional regulator
FOW48_15730	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOW48_15790	COG3320	Male sterility
FOW48_15790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOW48_15800	COG2814	Major facilitator Superfamily
FOW48_15805	COG1309	transcriptional regulator
FOW48_15810	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_15815	COG1522	sequence-specific DNA binding
FOW48_15830	COG0346	lactoylglutathione lyase activity
FOW48_15930	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOW48_15960	COG0789	Transcriptional regulator
FOW48_15965	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOW48_15985	COG0577	efflux transmembrane transporter activity
FOW48_16005	COG3850	Histidine kinase
FOW48_16005	COG5002	protein histidine kinase activity
FOW48_16015	COG2364	Membrane
FOW48_16020	COG1846	Transcriptional regulator
FOW48_16025	COG0456	acetyltransferase
FOW48_16030	COG2808	Putative FMN-binding domain
FOW48_16035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOW48_16065	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOW48_16100	COG0662	Cupin 2, conserved barrel domain protein
FOW48_16110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOW48_16110	COG2207	Transcriptional regulator
FOW48_16135	COG3409	Peptidoglycan-binding domain 1 protein
FOW48_16135	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOW48_16175	COG0477	Major facilitator Superfamily
FOW48_16190	COG1846	Transcriptional regulator
FOW48_16195	COG2814	Major facilitator Superfamily
FOW48_16205	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOW48_16230	COG2076	Multidrug Resistance protein
FOW48_16250	COG2031	fatty acid transporter
FOW48_16260	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOW48_16310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOW48_16315	COG1288	antiporter activity
FOW48_16360	COG3344	reverse transcriptase
FOW48_16370	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOW48_16370	COG0456	acetyltransferase
FOW48_16375	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOW48_16395	COG1733	regulation of RNA biosynthetic process
FOW48_16400	COG0778	Nitroreductase
FOW48_16420	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_16430	COG1131	(ABC) transporter
FOW48_16460	COG1011	Hydrolase
FOW48_16485	COG0346	lactoylglutathione lyase activity
FOW48_16490	COG1940	carbohydrate kinase activity
FOW48_16495	COG0110	maltose O-acetyltransferase activity
FOW48_16500	COG0180	Tryptophanyl-tRNA synthetase
FOW48_16510	COG0628	permease
FOW48_16535	COG2226	methyltransferase
FOW48_16545	COG0477	Major facilitator Superfamily
FOW48_16570	COG1253	flavin adenine dinucleotide binding
FOW48_16575	COG0789	Transcriptional regulator
FOW48_16585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOW48_16615	COG0697	spore germination
FOW48_16620	COG1357	PFAM Pentapeptide repeats (8 copies)
FOW48_16625	COG3813	Protein conserved in bacteria
FOW48_16630	COG2706	6-phosphogluconolactonase activity
FOW48_16635	COG1070	Carbohydrate kinase
FOW48_16645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOW48_16650	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOW48_16665	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOW48_16670	COG0604	alcohol dehydrogenase
FOW48_16675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOW48_16690	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_16705	COG0656	L-ascorbic acid biosynthetic process
FOW48_16710	COG2814	Major facilitator Superfamily
FOW48_16725	COG0814	amino acid
FOW48_16735	COG3344	reverse transcriptase
FOW48_16765	COG1393	Belongs to the ArsC family
FOW48_16775	COG2188	Transcriptional regulator
FOW48_16780	COG0673	inositol 2-dehydrogenase activity
FOW48_16785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOW48_16790	COG1733	regulation of RNA biosynthetic process
FOW48_16795	COG1733	regulation of RNA biosynthetic process
FOW48_16815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOW48_16835	COG0384	phenazine biosynthesis protein PhzF
FOW48_16855	COG0318	PFAM AMP-dependent synthetase and ligase
FOW48_16860	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOW48_16865	COG1733	regulation of RNA biosynthetic process
FOW48_16900	COG1266	CAAX protease self-immunity
FOW48_16905	COG1309	transcriptional regulator
FOW48_16950	COG1151	hydroxylamine reductase activity
FOW48_16960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOW48_16990	COG2072	flavoprotein involved in K transport
FOW48_17035	COG1695	Transcriptional regulator
FOW48_17040	COG0604	alcohol dehydrogenase
FOW48_17045	COG1113	amino acid transport
FOW48_17050	COG2814	Major facilitator Superfamily
FOW48_17075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOW48_17080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOW48_17095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOW48_17100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOW48_17105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOW48_17110	COG3739	integral membrane protein
FOW48_17140	COG0583	DNA-binding transcription factor activity
FOW48_17160	COG1193	negative regulation of DNA recombination
FOW48_17165	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FOW48_17170	COG1164	Oligoendopeptidase f
FOW48_17215	COG0640	Transcriptional regulator
FOW48_17220	COG0604	alcohol dehydrogenase
FOW48_17230	COG0457	Tetratricopeptide repeat
FOW48_17240	COG2808	Putative FMN-binding domain
FOW48_17255	COG0385	Bile acid
FOW48_17260	COG0277	FAD linked oxidase domain protein
FOW48_17295	COG1285	pathogenesis
FOW48_17310	COG2514	catechol 2,3-dioxygenase activity
FOW48_17320	COG1126	abc transporter atp-binding protein
FOW48_17325	COG0765	amino acid transport
FOW48_17330	COG2720	vancomycin resistance protein
FOW48_17355	COG1278	Cold shock
FOW48_17365	COG0716	FMN binding
FOW48_17375	COG0494	nUDIX hydrolase
FOW48_17395	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_17405	COG0165	Argininosuccinate lyase
FOW48_17420	COG4145	pantothenate transmembrane transporter activity
FOW48_17470	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_17480	COG1657	PFAM Prenyltransferase squalene oxidase
FOW48_17485	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOW48_17490	COG2962	Rard protein
FOW48_17495	COG3326	Membrane
FOW48_17510	COG0489	protein tyrosine kinase activity
FOW48_17520	COG0314	molybdopterin synthase activity
FOW48_17525	COG0303	'Molybdopterin
FOW48_17530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOW48_17535	COG2116	formate transmembrane transporter activity
FOW48_17545	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOW48_17550	COG5609	conserved protein (DUF2294)
FOW48_17555	COG2427	Protein of unknown function (DUF1641)
FOW48_17560	COG3383	formate dehydrogenase (NAD+) activity
FOW48_17565	COG0697	spore germination
FOW48_17610	COG2226	methyltransferase
FOW48_17630	COG1301	dicarboxylic acid transport
FOW48_17635	COG1316	TRANSCRIPTIONal
FOW48_17645	COG1595	DNA-templated transcription, initiation
FOW48_17650	COG0346	lactoylglutathione lyase activity
FOW48_17660	COG1131	(ABC) transporter
FOW48_17670	COG0673	inositol 2-dehydrogenase activity
FOW48_17675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOW48_17680	COG0187	DNA topoisomerase II activity
FOW48_17685	COG1832	CoA-binding protein
FOW48_17690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOW48_17695	COG0745	RESPONSE REGULATOR receiver
FOW48_17705	COG1328	CTP reductase activity
FOW48_17705	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOW48_17715	COG4841	protein insertion into membrane
FOW48_17720	COG0824	Thioesterase
FOW48_17755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOW48_17765	COG1132	(ABC) transporter
FOW48_17770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOW48_17780	COG0726	polysaccharide deacetylase
FOW48_17800	COG2211	Major facilitator Superfamily
FOW48_17800	COG2211	Major facilitator Superfamily
FOW48_17805	COG4282	regulation of fungal-type cell wall biogenesis
FOW48_17825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOW48_17860	COG1268	BioY protein
FOW48_17865	COG0318	PFAM AMP-dependent synthetase and ligase
FOW48_17925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOW48_17945	COG0400	carboxylic ester hydrolase activity
FOW48_17950	COG0346	lactoylglutathione lyase activity
FOW48_17955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOW48_17970	COG1902	pentaerythritol trinitrate reductase activity
FOW48_17975	COG1329	Transcriptional regulator
FOW48_17980	COG0010	Belongs to the arginase family
FOW48_18015	COG2226	methyltransferase
FOW48_18060	COG3344	reverse transcriptase
FOW48_18070	COG4846	Membrane protein involved in cytochrome C biogenesis
FOW48_18075	COG0785	Cytochrome C biogenesis protein
FOW48_18100	COG1131	(ABC) transporter
FOW48_18115	COG0583	DNA-binding transcription factor activity
FOW48_18125	COG1346	cytolysis
FOW48_18140	COG0730	response to heat
FOW48_18150	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOW48_18150	COG3409	Peptidoglycan-binding domain 1 protein
FOW48_18165	COG1132	(ABC) transporter
FOW48_18170	COG1132	(ABC) transporter
FOW48_18295	COG3639	organic phosphonate transmembrane transporter activity
FOW48_18300	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOW48_18305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOW48_18310	COG0737	Belongs to the 5'-nucleotidase family
FOW48_18320	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOW48_18340	COG1695	Transcriptional regulator
FOW48_18345	COG0174	glutamine synthetase
FOW48_18350	COG0789	Transcriptional regulator
FOW48_18355	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOW48_18360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOW48_18365	COG2860	membrane
FOW48_18370	COG0464	growth
FOW48_18400	COG1388	LysM domain
FOW48_18400	COG3584	3D domain protein
FOW48_18405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOW48_18405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOW48_18405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOW48_18410	COG1105	Belongs to the carbohydrate kinase PfkB family
FOW48_18415	COG1349	DNA-binding transcription factor activity
FOW48_18420	COG1979	alcohol dehydrogenase
FOW48_18425	COG2322	membrane
FOW48_18435	COG1113	amino acid transport
FOW48_18450	COG1408	metallophosphoesterase
FOW48_18455	COG2116	formate transmembrane transporter activity
FOW48_18470	COG2217	Heavy metal translocating P-type atpase
FOW48_18475	COG2608	mercury ion transmembrane transporter activity
FOW48_18480	COG1937	Protein conserved in bacteria
FOW48_18490	COG2819	hydrolase of the alpha beta superfamily
FOW48_18495	COG1120	ATPase activity
FOW48_18500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOW48_18505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOW48_18510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOW48_18520	COG2169	Transcriptional regulator
FOW48_18525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOW48_18530	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOW48_18540	COG2364	Membrane
FOW48_18605	COG1368	sulfuric ester hydrolase activity
FOW48_18610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOW48_18620	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOW48_18675	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOW48_18685	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOW48_18690	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOW48_18690	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOW48_18700	COG2359	stage V sporulation protein S
FOW48_18705	COG1692	metallophosphoesterase
FOW48_18730	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOW48_18735	COG1426	Protein conserved in bacteria
FOW48_18750	COG0300	oxidoreductase activity
FOW48_18760	COG0612	Peptidase, M16
FOW48_18785	COG2188	Transcriptional regulator
FOW48_18795	COG1674	ftsk spoiiie
FOW48_18805	COG0740	serine-type endopeptidase activity
FOW48_18810	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOW48_18820	COG0527	aspartate kinase activity
FOW48_18825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOW48_18830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOW48_18835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOW48_18850	COG0726	polysaccharide deacetylase
FOW48_18865	COG0196	riboflavin kinase activity
FOW48_18880	COG1550	Protein conserved in bacteria
FOW48_18890	COG1358	cellular component organization or biogenesis
FOW48_18895	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOW48_18900	COG0195	Participates in both transcription termination and antitermination
FOW48_18920	COG0750	zinc metalloprotease
FOW48_18930	COG4589	Belongs to the CDS family
FOW48_18945	COG0528	UMP kinase activity
FOW48_18975	COG4974	Belongs to the 'phage' integrase family
FOW48_18985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOW48_18990	COG0758	DNA mediated transformation
FOW48_18995	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOW48_19035	COG1837	Belongs to the UPF0109 family
FOW48_19045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOW48_19055	COG0552	protein localization to endoplasmic reticulum
FOW48_19060	COG1196	nuclear chromosome segregation
FOW48_19075	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_19095	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOW48_19100	COG1461	Dihydroxyacetone kinase
FOW48_19105	COG1302	Protein conserved in bacteria
FOW48_19120	COG1564	THIamine pyrophosphokinase
FOW48_19125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOW48_19135	COG0515	serine threonine protein kinase
FOW48_19135	COG2815	serine threonine protein kinase
FOW48_19140	COG0631	protein serine/threonine phosphatase activity
FOW48_19150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOW48_19150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOW48_19160	COG0242	peptide deformylase activity
FOW48_19165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOW48_19170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOW48_19180	COG0194	GDP metabolic process
FOW48_19190	COG1561	YicC-like family, N-terminal region
FOW48_19195	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOW48_19230	COG3069	C4-dicarboxylate transmembrane transporter activity
FOW48_19295	COG0564	pseudouridine synthase activity
FOW48_19315	COG3599	regulation of cell shape
FOW48_19320	COG2302	S4 RNA-binding domain
FOW48_19325	COG0762	integral membrane protein
FOW48_19335	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOW48_19345	COG1873	PFAM PRC-barrel domain
FOW48_19350	COG1191	sigma factor activity
FOW48_19355	COG1191	sigma factor activity
FOW48_19365	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOW48_19370	COG0849	cell division
FOW48_19375	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOW48_19390	COG0772	Belongs to the SEDS family
FOW48_19405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOW48_19420	COG4839	cell division protein FtsL
FOW48_19455	COG1399	metal-binding, possibly nucleic acid-binding protein
FOW48_19580	COG0740	serine-type endopeptidase activity
FOW48_19590	COG4626	Terminase
FOW48_19590	COG1802	Transcriptional regulator
FOW48_19610	COG0582	viral genome integration into host DNA
FOW48_19680	COG1484	DNA-dependent DNA replication
FOW48_19705	COG1396	sequence-specific DNA binding
FOW48_19730	COG0582	viral genome integration into host DNA
FOW48_19740	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOW48_19745	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOW48_19750	COG3314	Sporulation integral membrane protein YlbJ
FOW48_19760	COG0742	ribosomal rna small subunit methyltransferase
FOW48_19785	COG3679	Belongs to the UPF0342 family
FOW48_19790	COG0406	alpha-ribazole phosphatase activity
FOW48_19805	COG2340	Cysteine-rich secretory protein family
FOW48_19820	COG3344	reverse transcriptase
FOW48_19830	COG3336	cytochrome c oxidase
FOW48_19865	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOW48_19875	COG0772	Belongs to the SEDS family
FOW48_19885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOW48_19890	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOW48_19900	COG4896	Protein conserved in bacteria
FOW48_19925	COG0483	inositol monophosphate 1-phosphatase activity
FOW48_19945	COG1982	Orn Lys Arg decarboxylase major
FOW48_19995	COG0022	dehydrogenase e1 component
FOW48_20000	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOW48_20010	COG0242	peptide deformylase activity
FOW48_20015	COG0561	phosphatase activity
FOW48_20030	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOW48_20035	COG0569	domain protein
FOW48_20055	COG0583	DNA-binding transcription factor activity
FOW48_20060	COG0517	IMP dehydrogenase activity
FOW48_20070	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOW48_20075	COG4703	Protein of unknown function (DUF1797)
FOW48_20090	COG2200	EAL domain
FOW48_20095	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_20100	COG1408	metallophosphoesterase
FOW48_20175	COG3209	COG3209 Rhs family protein
FOW48_20185	COG2205	protein histidine kinase activity
FOW48_20195	COG0436	Aminotransferase
FOW48_20200	COG1609	Transcriptional regulator
FOW48_20205	COG3833	ABC-type maltose transport systems, permease component
FOW48_20210	COG1175	transmembrane transport
FOW48_20215	COG2182	Extracellular solute-binding protein
FOW48_20225	COG0366	Alpha amylase catalytic
FOW48_20230	COG3842	ATPase activity
FOW48_20270	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOW48_20275	COG0183	Belongs to the thiolase family
FOW48_20310	COG1695	Transcriptional regulator
FOW48_20315	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_20350	COG0436	Aminotransferase
FOW48_20385	COG2084	Dehydrogenase
FOW48_20395	COG3706	GGDEF domain
FOW48_20400	COG0778	Nitroreductase
FOW48_20425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOW48_20425	COG1263	PTS System
FOW48_20425	COG2190	(PTS) system
FOW48_20430	COG3711	transcriptional antiterminator
FOW48_20450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOW48_20485	COG0456	acetyltransferase
FOW48_20495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOW48_20500	COG4086	secreted protein
FOW48_20505	COG0561	phosphatase activity
FOW48_20510	COG0697	spore germination
FOW48_20525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOW48_20550	COG0733	neurotransmitter:sodium symporter activity
FOW48_20570	COG1686	Belongs to the peptidase S11 family
FOW48_20580	COG1725	Transcriptional regulator
FOW48_20585	COG1131	(ABC) transporter
FOW48_20600	COG1846	Transcriptional regulator
FOW48_20615	COG0598	Magnesium transport protein CorA
FOW48_20640	COG4974	Belongs to the 'phage' integrase family
FOW48_20650	COG0735	belongs to the Fur family
FOW48_20655	COG1300	Membrane
FOW48_20680	COG0656	L-ascorbic acid biosynthetic process
FOW48_20685	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOW48_20685	COG0456	acetyltransferase
FOW48_20695	COG4085	toxin activity
FOW48_20695	COG0737	Belongs to the 5'-nucleotidase family
FOW48_20695	COG1525	nuclease
FOW48_20705	COG0596	Alpha beta hydrolase
FOW48_20710	COG2056	Na+-H+ antiporter family
FOW48_20715	COG1609	Transcriptional regulator
FOW48_20725	COG1073	alpha beta
FOW48_20745	COG0307	riboflavin synthase, alpha
FOW48_20770	COG4106	trans-aconitate 2-methyltransferase activity
FOW48_20775	COG2226	methyltransferase
FOW48_20775	COG1073	alpha beta
FOW48_20790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOW48_20805	COG0737	Belongs to the 5'-nucleotidase family
FOW48_20815	COG1522	sequence-specific DNA binding
FOW48_20835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOW48_20860	COG0300	oxidoreductase activity
FOW48_20865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOW48_20870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOW48_20875	COG1760	l-serine dehydratase
FOW48_20880	COG1760	l-serine dehydratase
FOW48_20905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOW48_20915	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOW48_20930	COG1376	ErfK ybiS ycfS ynhG family protein
FOW48_20935	COG4129	membrane
FOW48_20940	COG1126	abc transporter atp-binding protein
FOW48_20945	COG0765	amino acid transport
FOW48_20950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOW48_20970	COG2323	membrane
FOW48_20975	COG0772	Belongs to the SEDS family
FOW48_20980	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOW48_20985	COG0022	dehydrogenase e1 component
FOW48_20990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOW48_20995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOW48_21005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOW48_21010	COG0280	phosphate acetyltransferase
FOW48_21015	COG3290	protein histidine kinase activity
FOW48_21015	COG3829	transcription factor binding
FOW48_21030	COG3093	addiction module antidote protein HigA
FOW48_21035	COG0745	RESPONSE REGULATOR receiver
FOW48_21045	COG0750	zinc metalloprotease
FOW48_21050	COG0497	DNA recombination
FOW48_21060	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOW48_21070	COG0142	geranyltranstransferase activity
FOW48_21095	COG1302	Protein conserved in bacteria
FOW48_21100	COG0439	Biotin carboxylase
FOW48_21105	COG0511	ligase activity, forming carbon-carbon bonds
FOW48_21150	COG3854	ATPases associated with a variety of cellular activities
FOW48_21190	COG3872	metal-dependent enzyme
FOW48_21230	COG0095	Lipoate-protein ligase
FOW48_21235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOW48_21240	COG1609	Transcriptional regulator
FOW48_21250	COG2076	Multidrug Resistance protein
FOW48_21255	COG2076	Multidrug Resistance protein
FOW48_21290	COG1131	(ABC) transporter
FOW48_21295	COG1725	Transcriptional regulator
FOW48_21325	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOW48_21380	COG4970	Tfp pilus assembly protein FimT
FOW48_21390	COG1459	type II secretion system
FOW48_21395	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOW48_21450	COG0646	methionine synthase
FOW48_21450	COG1410	methionine synthase
FOW48_21455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOW48_21455	COG0646	methionine synthase
FOW48_21460	COG0626	cystathionine gamma-synthase activity
FOW48_21465	COG0626	cystathionine gamma-synthase activity
FOW48_21485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOW48_21495	COG1940	carbohydrate kinase activity
FOW48_21500	COG4483	Protein conserved in bacteria
FOW48_21505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOW48_21515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOW48_21520	COG0704	Plays a role in the regulation of phosphate uptake
FOW48_21525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOW48_21530	COG0581	inorganic phosphate transmembrane transporter activity
FOW48_21535	COG0573	inorganic phosphate transmembrane transporter activity
FOW48_21540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOW48_21550	COG0477	Major facilitator Superfamily
FOW48_21555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOW48_21580	COG0735	belongs to the Fur family
FOW48_21585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOW48_21590	COG1121	(ABC) transporter
FOW48_21595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOW48_21625	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOW48_21630	COG2384	SAM-dependent methyltransferase
FOW48_21635	COG2010	Cytochrome c
FOW48_21640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOW48_21645	COG0358	DNA primase activity
FOW48_21655	COG0517	IMP dehydrogenase activity
FOW48_21670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOW48_21675	COG0295	cytidine deaminase activity
FOW48_21680	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOW48_21695	COG1702	phosphate starvation-inducible protein PhoH
FOW48_21710	COG1610	YqeY-like protein
FOW48_21720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOW48_21725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOW48_21760	COG1733	regulation of RNA biosynthetic process
FOW48_21785	COG1466	dna polymerase III delta subunit
FOW48_21800	COG2131	deaminase
FOW48_21805	COG1596	polysaccharide export
FOW48_21805	COG1555	photosystem II stabilization
FOW48_21810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOW48_21815	COG2226	methyltransferase
FOW48_21820	COG0799	negative regulation of ribosome biogenesis
FOW48_21825	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOW48_21835	COG1534	Rna-binding protein
FOW48_21845	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOW48_21850	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOW48_21865	COG1191	sigma factor activity
FOW48_21885	COG2357	RelA SpoT domain protein
FOW48_21895	COG1785	Belongs to the alkaline phosphatase family
FOW48_21900	COG0456	acetyltransferase
FOW48_21905	COG2267	carboxylic ester hydrolase activity
FOW48_21940	COG1404	Belongs to the peptidase S8 family
FOW48_21945	COG3186	Phenylalanine-4-hydroxylase
FOW48_21955	COG2514	catechol 2,3-dioxygenase activity
FOW48_21960	COG2259	Doxx family
FOW48_22000	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOW48_22015	COG0626	cystathionine gamma-synthase activity
FOW48_22020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOW48_22075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOW48_22105	COG0628	permease
FOW48_22125	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOW48_22145	COG1959	2 iron, 2 sulfur cluster binding
FOW48_22150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOW48_22170	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOW48_22195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOW48_22205	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOW48_22205	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOW48_22210	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOW48_22215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOW48_22215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOW48_22225	COG2244	polysaccharide biosynthetic process
FOW48_22230	COG2323	membrane
FOW48_22240	COG1862	Preprotein translocase
FOW48_22305	COG1104	cysteine desulfurase activity
FOW48_22310	COG1827	regulation of RNA biosynthetic process
FOW48_22315	COG2258	MOSC domain
FOW48_22325	COG0577	efflux transmembrane transporter activity
FOW48_22330	COG0577	efflux transmembrane transporter activity
FOW48_22335	COG1136	(ABC) transporter
FOW48_22340	COG5002	protein histidine kinase activity
FOW48_22345	COG0745	RESPONSE REGULATOR receiver
FOW48_22355	COG3290	protein histidine kinase activity
FOW48_22370	COG1530	ribonuclease E activity
FOW48_22375	COG1994	Peptidase M50
FOW48_22380	COG0739	heme binding
FOW48_22385	COG2894	cell division
FOW48_22400	COG1792	Involved in formation and maintenance of cell shape
FOW48_22405	COG1077	Cell shape determining protein MreB Mrl
FOW48_22430	COG0285	dihydrofolate synthase activity
FOW48_22465	COG0113	porphobilinogen synthase activity
FOW48_22470	COG1587	Uroporphyrinogen-III synthase
FOW48_22480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOW48_22490	COG1846	Transcriptional regulator
FOW48_22495	COG1764	response to oxidative stress
FOW48_22510	COG0470	DNA polymerase III
FOW48_22510	COG1067	ATP-dependent peptidase activity
FOW48_22560	COG0622	Phosphoesterase
FOW48_22575	COG5401	PFAM Sporulation and spore germination
FOW48_22595	COG1309	transcriptional regulator
FOW48_22610	COG2197	response regulator
FOW48_22615	COG2233	PERMEase
FOW48_22620	COG0402	S-adenosylhomocysteine deaminase activity
FOW48_22625	COG1983	PspC domain protein
FOW48_22635	COG0697	spore germination
FOW48_22645	COG1959	2 iron, 2 sulfur cluster binding
FOW48_22650	COG1668	transmembrane transport
FOW48_22655	COG4152	abc transporter atp-binding protein
FOW48_22660	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOW48_22665	COG1360	Flagellar Motor Protein
FOW48_22670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOW48_22675	COG1876	peptidase activity
FOW48_22680	COG0824	Thioesterase
FOW48_22685	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOW48_22690	COG1053	succinate dehydrogenase
FOW48_22695	COG2009	succinate dehydrogenase
FOW48_22700	COG1719	4-vinyl reductase, 4VR
FOW48_22710	COG3118	belongs to the thioredoxin family
FOW48_22715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOW48_22720	COG2086	electron transfer activity
FOW48_22725	COG1024	Enoyl-CoA hydratase
FOW48_22730	COG1309	transcriptional regulator
FOW48_22735	COG0318	PFAM AMP-dependent synthetase and ligase
FOW48_22745	COG2318	DinB family
FOW48_22765	COG1131	(ABC) transporter
FOW48_22770	COG2205	protein histidine kinase activity
FOW48_22775	COG0745	RESPONSE REGULATOR receiver
FOW48_22780	COG4895	conserved protein (DUF2196)
FOW48_22800	COG4509	Sortase family
FOW48_22805	COG1120	ATPase activity
FOW48_22820	COG5386	Cell surface protein
FOW48_22825	COG5386	Cell surface protein
FOW48_22830	COG1114	Component of the transport system for branched-chain amino acids
FOW48_22835	COG1187	pseudouridine synthase activity
FOW48_22845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOW48_22845	COG1796	DNA polymerase
FOW48_22850	COG1286	toxin biosynthetic process
FOW48_22895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOW48_22905	COG1418	mRNA catabolic process
FOW48_22915	COG2814	Major facilitator Superfamily
FOW48_22920	COG1566	PFAM secretion protein HlyD family protein
FOW48_22930	COG1363	Peptidase, m42
FOW48_22950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOW48_22955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOW48_22965	COG1484	DNA-dependent DNA replication
FOW48_22970	COG3611	Membrane attachment protein
FOW48_22980	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOW48_22985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOW48_22990	COG0237	dephospho-CoA kinase activity
FOW48_22995	COG1971	Probably functions as a manganese efflux pump
FOW48_23005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOW48_23005	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOW48_23015	COG0745	RESPONSE REGULATOR receiver
FOW48_23035	COG0538	isocitrate dehydrogenase activity
FOW48_23040	COG0372	Belongs to the citrate synthase family
FOW48_23055	COG0628	permease
FOW48_23060	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOW48_23085	COG1725	Transcriptional regulator
FOW48_23090	COG0281	malic enzyme
FOW48_23095	COG0587	DNA-directed DNA polymerase activity
FOW48_23110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOW48_23140	COG4109	DRTGG domain
FOW48_23150	COG0006	proline dipeptidase activity
FOW48_23185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOW48_23190	COG0662	Cupin 2, conserved barrel domain protein
FOW48_23205	COG1028	Short-chain dehydrogenase reductase Sdr
FOW48_23210	COG0589	response to stress
FOW48_23275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOW48_23300	COG0827	DNA restriction-modification system
FOW48_23305	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOW48_23310	COG3874	Sporulation protein YtfJ
FOW48_23320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOW48_23325	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOW48_23335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOW48_23350	COG1104	cysteine desulfurase activity
FOW48_23360	COG0583	DNA-binding transcription factor activity
FOW48_23365	COG0697	spore germination
FOW48_23370	COG1309	transcriptional regulator
FOW48_23375	COG1956	GAF domain-containing protein
FOW48_23380	COG0626	cystathionine gamma-synthase activity
FOW48_23410	COG1595	DNA-templated transcription, initiation
FOW48_23425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOW48_23430	COG0454	-acetyltransferase
FOW48_23435	COG0517	IMP dehydrogenase activity
FOW48_23455	COG0745	RESPONSE REGULATOR receiver
FOW48_23495	COG1609	Transcriptional regulator
FOW48_23505	COG4851	CamS sex pheromone cAM373 precursor
FOW48_23510	COG3118	belongs to the thioredoxin family
FOW48_23520	COG2309	aminopeptidase activity
FOW48_23540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOW48_23565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOW48_23575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOW48_23580	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOW48_23585	COG1363	Peptidase, m42
FOW48_23595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOW48_23610	COG0510	thiamine kinase activity
FOW48_23615	COG1523	belongs to the glycosyl hydrolase 13 family
FOW48_23625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOW48_23630	COG1349	DNA-binding transcription factor activity
FOW48_23635	COG1187	pseudouridine synthase activity
FOW48_23640	COG2244	polysaccharide biosynthetic process
FOW48_23645	COG2081	HI0933 family
FOW48_23650	COG2814	Major facilitator Superfamily
FOW48_23660	COG3832	glyoxalase III activity
FOW48_23685	COG1329	Transcriptional regulator
FOW48_23710	COG0314	molybdopterin synthase activity
FOW48_23715	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOW48_23720	COG0303	'Molybdopterin
FOW48_23730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOW48_23735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOW48_23760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOW48_23770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOW48_23810	COG2814	Major facilitator Superfamily
FOW48_23815	COG0475	glutathione-regulated potassium exporter activity
FOW48_23820	COG0490	domain, Protein
FOW48_23825	COG0582	viral genome integration into host DNA
FOW48_23840	COG1136	(ABC) transporter
FOW48_23860	COG1242	4 iron, 4 sulfur cluster binding
FOW48_23865	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOW48_23885	COG1794	racemase activity, acting on amino acids and derivatives
FOW48_23915	COG2267	carboxylic ester hydrolase activity
FOW48_23920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOW48_23925	COG0671	phosphoesterase, PA-phosphatase related
FOW48_23930	COG0438	transferase activity, transferring glycosyl groups
FOW48_23940	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOW48_23950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOW48_23995	COG5002	protein histidine kinase activity
FOW48_24000	COG4191	Histidine kinase
FOW48_24005	COG2267	carboxylic ester hydrolase activity
FOW48_24010	COG1368	sulfuric ester hydrolase activity
FOW48_24030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOW48_24035	COG1116	anion transmembrane transporter activity
FOW48_24040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOW48_24065	COG0494	nUDIX hydrolase
FOW48_24100	COG0288	reversible hydration of carbon dioxide
FOW48_24105	COG1271	oxidase subunit
FOW48_24110	COG1294	oxidase, subunit
FOW48_24130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOW48_24155	COG1842	Phage shock protein A
FOW48_24190	COG5002	protein histidine kinase activity
FOW48_24195	COG0745	RESPONSE REGULATOR receiver
FOW48_24230	COG1597	lipid kinase activity
FOW48_24250	COG0577	efflux transmembrane transporter activity
FOW48_24255	COG1136	(ABC) transporter
FOW48_24270	COG0586	Pfam SNARE associated Golgi protein
FOW48_24290	COG0577	efflux transmembrane transporter activity
FOW48_24295	COG1136	(ABC) transporter
FOW48_24300	COG3708	Transcriptional regulator
FOW48_24300	COG2207	Transcriptional regulator
FOW48_24305	COG5658	integral membrane protein
FOW48_24310	COG0640	Transcriptional regulator
FOW48_24315	COG0745	RESPONSE REGULATOR receiver
FOW48_24320	COG2205	protein histidine kinase activity
FOW48_24340	COG0577	efflux transmembrane transporter activity
FOW48_24375	COG3964	amidohydrolase
FOW48_24395	COG4948	Mandelate Racemase Muconate Lactonizing
FOW48_24405	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOW48_24410	COG0596	Alpha beta hydrolase
FOW48_24420	COG1169	isochorismate synthase
FOW48_24425	COG1575	Belongs to the MenA family. Type 1 subfamily
FOW48_24430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOW48_24435	COG1278	Cold shock
FOW48_24455	COG0058	SHG alpha-glucan phosphorylase activity
FOW48_24465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOW48_24485	COG1404	Belongs to the peptidase S8 family
FOW48_24585	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOW48_24620	COG1285	pathogenesis
FOW48_24625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOW48_24645	COG2155	Conserved Protein
FOW48_24650	COG1098	S1 RNA binding domain
FOW48_24655	COG0436	Aminotransferase
FOW48_24660	COG1522	sequence-specific DNA binding
FOW48_24665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOW48_24670	COG2267	carboxylic ester hydrolase activity
FOW48_24680	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOW48_24695	COG5018	Exonuclease
FOW48_24700	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOW48_24720	COG2050	protein possibly involved in aromatic compounds catabolism
FOW48_24730	COG1268	BioY protein
FOW48_24740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOW48_24745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOW48_24760	COG3584	3D domain protein
FOW48_24775	COG1252	NADH dehydrogenase
FOW48_24785	COG3708	Transcriptional regulator
FOW48_24800	COG1683	Conserved Protein
FOW48_24820	COG0316	Belongs to the HesB IscA family
FOW48_24835	COG1252	NADH dehydrogenase
FOW48_24845	COG2274	protein secretion by the type I secretion system
FOW48_24850	COG0390	transport system, permease component
FOW48_24860	COG2824	Alkylphosphonate utilization operon protein PhnA
FOW48_24900	COG4837	Protein of unknown function (DUF1462)
FOW48_24905	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOW48_24915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOW48_24920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOW48_24930	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOW48_24935	COG0647	UMP catabolic process
FOW48_24945	COG2445	Protein of unknown function DUF86
FOW48_24950	COG1494	fructose-1,6-bisphosphatase
FOW48_24970	COG4470	Protein conserved in bacteria
FOW48_24980	COG0789	Transcriptional regulator
FOW48_24990	COG4377	Putative membrane peptidase family (DUF2324)
FOW48_25015	COG0739	heme binding
FOW48_25025	COG3377	Domain of unknown function (DUF1805)
FOW48_25030	COG0737	Belongs to the 5'-nucleotidase family
FOW48_25040	COG0719	Fe-S assembly protein
FOW48_25045	COG0822	iron-sulfur transferase activity
FOW48_25050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOW48_25055	COG0719	Fe-S assembly protein
FOW48_25060	COG0396	ATPase activity
FOW48_25065	COG1464	Belongs to the NlpA lipoprotein family
FOW48_25070	COG1464	Belongs to the NlpA lipoprotein family
FOW48_25075	COG2011	ABC-type metal ion transport system permease component
FOW48_25080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOW48_25095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOW48_25100	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOW48_25110	COG1393	Belongs to the ArsC family
FOW48_25180	COG1309	transcriptional regulator
FOW48_25185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOW48_25190	COG1960	acyl-CoA dehydrogenase activity
FOW48_25200	COG0183	Belongs to the thiolase family
FOW48_25205	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOW48_25205	COG1024	Enoyl-CoA hydratase
FOW48_25220	COG1686	Belongs to the peptidase S11 family
FOW48_25235	COG0011	TIGRFAM Protein of
FOW48_25240	COG0840	transmembrane signaling receptor activity
FOW48_25260	COG2814	Major facilitator Superfamily
FOW48_25265	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FOW48_25305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOW48_25340	COG0586	Pfam SNARE associated Golgi protein
FOW48_25350	COG1376	ErfK ybiS ycfS ynhG family protein
FOW48_25355	COG0745	RESPONSE REGULATOR receiver
FOW48_25360	COG5002	protein histidine kinase activity
FOW48_25390	COG0840	transmembrane signaling receptor activity
FOW48_25395	COG2151	metal-sulfur cluster biosynthetic enzyme
FOW48_25400	COG3227	Zinc metalloprotease (Elastase)
FOW48_25405	COG1741	Belongs to the pirin family
FOW48_25425	COG0475	glutathione-regulated potassium exporter activity
FOW48_25430	COG0490	domain, Protein
FOW48_25435	COG1115	amino acid carrier protein
FOW48_25450	COG0783	Belongs to the Dps family
FOW48_25470	COG1611	Belongs to the LOG family
FOW48_25490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOW48_25495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOW48_25500	COG1115	amino acid carrier protein
FOW48_25505	COG1115	amino acid carrier protein
FOW48_25510	COG2910	NAD(P)H-binding
FOW48_25530	COG0656	L-ascorbic acid biosynthetic process
FOW48_25540	COG1733	regulation of RNA biosynthetic process
FOW48_25550	COG1252	NADH dehydrogenase
FOW48_25555	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOW48_25585	COG0840	transmembrane signaling receptor activity
FOW48_25585	COG3290	protein histidine kinase activity
FOW48_25595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOW48_25620	COG0488	(ABC) transporter
FOW48_25625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOW48_25630	COG3223	Belongs to the PsiE family
FOW48_25675	COG1136	(ABC) transporter
FOW48_25695	COG0586	Pfam SNARE associated Golgi protein
FOW48_25700	COG3963	phosphatidate phosphatase activity
FOW48_25740	COG0756	dUTP diphosphatase activity
FOW48_25745	COG2207	Transcriptional regulator
FOW48_25745	COG3708	Transcriptional regulator
FOW48_25760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOW48_25775	COG0640	Transcriptional regulator
FOW48_25780	COG2311	Membrane
FOW48_25820	COG0577	efflux transmembrane transporter activity
FOW48_25825	COG1136	(ABC) transporter
FOW48_25875	COG0557	exoribonuclease II activity
FOW48_25880	COG1647	Serine aminopeptidase, S33
FOW48_25885	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOW48_25890	COG1346	cytolysis
FOW48_25925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOW48_25940	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOW48_25965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOW48_25980	COG2323	membrane
FOW48_25995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOW48_26005	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOW48_26015	COG1051	belongs to the nudix hydrolase family
FOW48_26025	COG0492	ferredoxin-NADP+ reductase activity
FOW48_26030	COG0457	Tetratricopeptide repeat
FOW48_26035	COG0110	maltose O-acetyltransferase activity
FOW48_26055	COG1950	PFAM Membrane protein of
FOW48_26065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOW48_26080	COG0789	Transcriptional regulator
FOW48_26115	COG0583	DNA-binding transcription factor activity
FOW48_26125	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOW48_26130	COG0488	(ABC) transporter
FOW48_26140	COG1132	(ABC) transporter
FOW48_26145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOW48_26150	COG0793	Belongs to the peptidase S41A family
FOW48_26150	COG3409	Peptidoglycan-binding domain 1 protein
FOW48_26155	COG2177	Part of the ABC transporter FtsEX involved in
FOW48_26160	COG2884	Cell division ATP-binding protein ftsE
FOW48_26180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOW48_26185	COG1278	Cold shock
FOW48_26190	COG1040	competence protein
FOW48_26195	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOW48_26200	COG1388	LysM domain
FOW48_26200	COG0791	NLP P60 protein
FOW48_26205	COG1733	regulation of RNA biosynthetic process
FOW48_26210	COG1307	EDD domain protein, DegV family
FOW48_26215	COG1739	Uncharacterized protein family UPF0029
FOW48_26220	COG1316	TRANSCRIPTIONal
FOW48_26225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOW48_26230	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOW48_26235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOW48_26245	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOW48_26245	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOW48_26265	COG1486	melibiose metabolic process
FOW48_26270	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOW48_26275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOW48_26285	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOW48_26305	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOW48_26315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOW48_26320	COG1301	dicarboxylic acid transport
FOW48_26335	COG0346	lactoylglutathione lyase activity
FOW48_26365	COG0583	DNA-binding transcription factor activity
FOW48_26370	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOW48_26375	COG1271	oxidase subunit
FOW48_26395	COG1620	l-lactate permease
FOW48_26405	COG2389	metal-binding protein
FOW48_26420	COG1368	sulfuric ester hydrolase activity
FOW48_26430	COG0791	NLP P60 protein
FOW48_26430	COG1388	LysM domain
FOW48_26540	COG0484	heat shock protein binding
FOW48_26600	COG1923	regulation of RNA biosynthetic process
FOW48_26670	COG3209	COG3209 Rhs family protein
FOW48_26680	COG0582	viral genome integration into host DNA
FOW48_26790	COG0662	Cupin 2, conserved barrel domain protein
FOW48_26805	COG3344	reverse transcriptase
FOW48_26870	COG1923	regulation of RNA biosynthetic process
FOW48_26920	COG3209	COG3209 Rhs family protein
FOW48_26965	COG2002	toxin-antitoxin pair type II binding
FOW48_26970	COG1923	regulation of RNA biosynthetic process