locus-tag	class	description
LU294_00010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LU294_00020	COG0706	membrane insertase activity
LU294_00025	COG1847	R3H domain protein
LU294_00050	COG1192	Involved in chromosome partitioning
LU294_00055	COG1475	DNA binding
LU294_00065	COG0668	transmembrane transport
LU294_00070	COG4481	Protein conserved in bacteria
LU294_00075	COG0012	GTP binding
LU294_00085	COG0629	single-stranded DNA binding
LU294_00095	COG4241	membrane
LU294_00100	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LU294_00110	COG0305	Participates in initiation and elongation during chromosome replication
LU294_00140	COG0745	RESPONSE REGULATOR receiver
LU294_00145	COG5002	protein histidine kinase activity
LU294_00150	COG4863	YycH protein
LU294_00155	COG4853	Protein conserved in bacteria
LU294_00160	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LU294_00165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LU294_00185	COG1164	Oligoendopeptidase f
LU294_00205	COG1272	protein, Hemolysin III
LU294_00210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LU294_00255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LU294_00260	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LU294_00265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LU294_00270	COG2814	Major facilitator Superfamily
LU294_00275	COG3275	phosphorelay sensor kinase activity
LU294_00280	COG3279	Response regulator of the LytR AlgR family
LU294_00295	COG0628	permease
LU294_00305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LU294_00305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LU294_00310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LU294_00315	COG1309	transcriptional regulator
LU294_00320	COG0488	(ABC) transporter
LU294_00335	COG1216	Glycosyl transferase, family 2
LU294_00350	COG1216	Glycosyl transferase, family 2
LU294_00355	COG1607	acyl-coa hydrolase
LU294_00365	COG0840	transmembrane signaling receptor activity
LU294_00380	COG0438	transferase activity, transferring glycosyl groups
LU294_00390	COG0477	Major facilitator Superfamily
LU294_00395	COG3279	Response regulator of the LytR AlgR family
LU294_00400	COG1966	Carbon starvation protein
LU294_00405	COG2879	small protein
LU294_00410	COG3706	GGDEF domain
LU294_00415	COG0351	phosphomethylpyrimidine kinase
LU294_00420	COG2203	Gaf domain
LU294_00420	COG4585	Histidine kinase
LU294_00425	COG2197	response regulator
LU294_00435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LU294_00440	COG1011	Hydrolase
LU294_00445	COG2873	o-acetylhomoserine
LU294_00455	COG0460	homoserine dehydrogenase
LU294_00465	COG1609	Transcriptional regulator
LU294_00470	COG2755	lipolytic protein G-D-S-L family
LU294_00475	COG1131	(ABC) transporter
LU294_00480	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LU294_00490	COG2814	Major facilitator Superfamily
LU294_00495	COG0561	phosphatase activity
LU294_00500	COG2233	PERMEase
LU294_00505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LU294_00515	COG2363	Small membrane protein
LU294_00525	COG3773	Cell wall hydrolase
LU294_00540	COG0280	phosphate acetyltransferase
LU294_00545	COG0095	Lipoate-protein ligase
LU294_00565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LU294_00570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LU294_00575	COG1120	ATPase activity
LU294_00580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LU294_00585	COG1078	dGTPase activity
LU294_00595	COG1994	Peptidase M50
LU294_00605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LU294_00610	COG0584	glycerophosphoryl diester phosphodiesterase
LU294_00615	COG0789	Transcriptional regulator
LU294_00620	COG2814	Major facilitator Superfamily
LU294_00645	COG1619	proteins homologs of microcin C7 resistance protein MccF
LU294_00650	COG4506	Protein conserved in bacteria
LU294_00660	COG1595	DNA-templated transcription, initiation
LU294_00680	COG2234	aminopeptidase activity
LU294_00690	COG0024	Methionine aminopeptidase
LU294_00695	COG1131	(ABC) transporter
LU294_00700	COG0842	Transport permease protein
LU294_00705	COG4585	Histidine kinase
LU294_00710	COG2197	response regulator
LU294_00730	COG5001	Diguanylate cyclase
LU294_00730	COG3300	MHYT domain
LU294_00740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LU294_00745	COG2181	nitrate reductase activity
LU294_00745	COG0247	lactate metabolic process
LU294_00750	COG0183	Belongs to the thiolase family
LU294_00755	COG1250	3-hydroxyacyl-CoA dehydrogenase
LU294_00760	COG1960	acyl-CoA dehydrogenase activity
LU294_00765	COG1960	acyl-CoA dehydrogenase activity
LU294_00785	COG4821	SIS domain
LU294_00805	COG1494	fructose-1,6-bisphosphatase
LU294_00810	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LU294_00830	COG2890	protein-(glutamine-N5) methyltransferase activity
LU294_00845	COG0009	L-threonylcarbamoyladenylate synthase
LU294_00865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LU294_00870	COG2259	Doxx family
LU294_00875	COG2190	(PTS) system
LU294_00885	COG0698	ribose 5-phosphate isomerase
LU294_00920	COG0356	it plays a direct role in the translocation of protons across the membrane
LU294_00970	COG5001	Diguanylate cyclase
LU294_00970	COG3300	MHYT domain
LU294_00985	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LU294_01005	COG0839	Belongs to the complex I subunit 6 family
LU294_01015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LU294_01020	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LU294_01025	COG1007	ATP synthesis coupled electron transport
LU294_01030	COG4836	Membrane
LU294_01045	COG2385	sporulation resulting in formation of a cellular spore
LU294_01050	COG3279	Response regulator of the LytR AlgR family
LU294_01065	COG0739	heme binding
LU294_01075	COG1609	Transcriptional regulator
LU294_01090	COG0489	protein tyrosine kinase activity
LU294_01095	COG3944	biosynthesis protein
LU294_01100	COG0489	protein tyrosine kinase activity
LU294_01105	COG4464	protein tyrosine phosphatase activity
LU294_01110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LU294_01135	COG1215	transferase activity, transferring glycosyl groups
LU294_01140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LU294_01145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LU294_01150	COG1316	TRANSCRIPTIONal
LU294_01160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LU294_01165	COG0745	RESPONSE REGULATOR receiver
LU294_01170	COG5002	protein histidine kinase activity
LU294_01170	COG3850	Histidine kinase
LU294_01195	COG1136	(ABC) transporter
LU294_01200	COG0577	efflux transmembrane transporter activity
LU294_01255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LU294_01260	COG4715	Zinc finger, swim domain protein
LU294_01285	COG1388	LysM domain
LU294_01285	COG3584	3D domain protein
LU294_01290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LU294_01295	COG1215	transferase activity, transferring glycosyl groups
LU294_01305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LU294_01310	COG1388	LysM domain
LU294_01310	COG0791	NLP P60 protein
LU294_01320	COG1368	sulfuric ester hydrolase activity
LU294_01330	COG2389	metal-binding protein
LU294_01340	COG1620	l-lactate permease
LU294_01350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LU294_01355	COG1294	oxidase, subunit
LU294_01360	COG1271	oxidase subunit
LU294_01370	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LU294_01375	COG0583	DNA-binding transcription factor activity
LU294_01380	COG1511	domain protein
LU294_01385	COG0346	lactoylglutathione lyase activity
LU294_01395	COG1301	dicarboxylic acid transport
LU294_01400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LU294_01410	COG1447	Phosphotransferase system cellobiose-specific component IIA
LU294_01430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LU294_01435	COG1447	Phosphotransferase system cellobiose-specific component IIA
LU294_01440	COG1486	melibiose metabolic process
LU294_01460	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LU294_01460	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LU294_01470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LU294_01475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LU294_01480	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LU294_01485	COG1316	TRANSCRIPTIONal
LU294_01490	COG1739	Uncharacterized protein family UPF0029
LU294_01495	COG1307	EDD domain protein, DegV family
LU294_01500	COG1733	regulation of RNA biosynthetic process
LU294_01505	COG0791	NLP P60 protein
LU294_01510	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LU294_01515	COG1040	competence protein
LU294_01520	COG1278	Cold shock
LU294_01525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LU294_01545	COG2884	Cell division ATP-binding protein ftsE
LU294_01550	COG2177	Part of the ABC transporter FtsEX involved in
LU294_01555	COG3409	Peptidoglycan-binding domain 1 protein
LU294_01555	COG0793	Belongs to the peptidase S41A family
LU294_01560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LU294_01565	COG1132	(ABC) transporter
LU294_01575	COG0488	(ABC) transporter
LU294_01580	COG0655	NAD(P)H dehydrogenase (quinone) activity
LU294_01590	COG0583	DNA-binding transcription factor activity
LU294_01625	COG0789	Transcriptional regulator
LU294_01640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LU294_01650	COG1950	PFAM Membrane protein of
LU294_01670	COG0110	maltose O-acetyltransferase activity
LU294_01675	COG0457	Tetratricopeptide repeat
LU294_01680	COG0492	ferredoxin-NADP+ reductase activity
LU294_01690	COG1051	belongs to the nudix hydrolase family
LU294_01700	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LU294_01710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LU294_01720	COG2323	membrane
LU294_01735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LU294_01760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LU294_01775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LU294_01810	COG1346	cytolysis
LU294_01815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LU294_01820	COG1647	Serine aminopeptidase, S33
LU294_01825	COG0557	exoribonuclease II activity
LU294_01885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LU294_01900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LU294_01910	COG3290	protein histidine kinase activity
LU294_01910	COG0840	transmembrane signaling receptor activity
LU294_01925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LU294_01930	COG1252	NADH dehydrogenase
LU294_01940	COG1733	regulation of RNA biosynthetic process
LU294_01945	COG2814	Major facilitator Superfamily
LU294_01950	COG0656	L-ascorbic acid biosynthetic process
LU294_01965	COG2910	NAD(P)H-binding
LU294_01970	COG1115	amino acid carrier protein
LU294_01975	COG1115	amino acid carrier protein
LU294_01980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LU294_01985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LU294_02005	COG1611	Belongs to the LOG family
LU294_02020	COG0783	Belongs to the Dps family
LU294_02025	COG1115	amino acid carrier protein
LU294_02030	COG0490	domain, Protein
LU294_02035	COG0475	glutathione-regulated potassium exporter activity
LU294_02050	COG1741	Belongs to the pirin family
LU294_02055	COG3227	Zinc metalloprotease (Elastase)
LU294_02060	COG2151	metal-sulfur cluster biosynthetic enzyme
LU294_02065	COG0840	transmembrane signaling receptor activity
LU294_02090	COG5002	protein histidine kinase activity
LU294_02095	COG0745	RESPONSE REGULATOR receiver
LU294_02100	COG1376	ErfK ybiS ycfS ynhG family protein
LU294_02110	COG0586	Pfam SNARE associated Golgi protein
LU294_02145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LU294_02170	COG0531	amino acid
LU294_02180	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LU294_02185	COG2814	Major facilitator Superfamily
LU294_02210	COG0840	transmembrane signaling receptor activity
LU294_02215	COG0011	TIGRFAM Protein of
LU294_02230	COG1686	Belongs to the peptidase S11 family
LU294_02240	COG1250	3-hydroxyacyl-CoA dehydrogenase
LU294_02240	COG1024	Enoyl-CoA hydratase
LU294_02245	COG0183	Belongs to the thiolase family
LU294_02250	COG1960	acyl-CoA dehydrogenase activity
LU294_02255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LU294_02260	COG1309	transcriptional regulator
LU294_02265	COG1396	sequence-specific DNA binding
LU294_02315	COG1393	Belongs to the ArsC family
LU294_02325	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LU294_02330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LU294_02345	COG2011	ABC-type metal ion transport system permease component
LU294_02350	COG1464	Belongs to the NlpA lipoprotein family
LU294_02355	COG1464	Belongs to the NlpA lipoprotein family
LU294_02360	COG0396	ATPase activity
LU294_02365	COG0719	Fe-S assembly protein
LU294_02370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LU294_02375	COG0822	iron-sulfur transferase activity
LU294_02380	COG0719	Fe-S assembly protein
LU294_02385	COG0737	Belongs to the 5'-nucleotidase family
LU294_02390	COG3377	Domain of unknown function (DUF1805)
LU294_02400	COG0739	heme binding
LU294_02425	COG4377	Putative membrane peptidase family (DUF2324)
LU294_02430	COG0789	Transcriptional regulator
LU294_02440	COG4470	Protein conserved in bacteria
LU294_02455	COG1494	fructose-1,6-bisphosphatase
LU294_02460	COG2445	Protein of unknown function DUF86
LU294_02470	COG0647	UMP catabolic process
LU294_02480	COG2249	NAD(P)H dehydrogenase (quinone) activity
LU294_02490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LU294_02495	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LU294_02505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LU294_02510	COG4837	Protein of unknown function (DUF1462)
LU294_02530	COG2824	Alkylphosphonate utilization operon protein PhnA
LU294_02535	COG0390	transport system, permease component
LU294_02540	COG2274	protein secretion by the type I secretion system
LU294_02550	COG1252	NADH dehydrogenase
LU294_02565	COG0316	Belongs to the HesB IscA family
LU294_02580	COG1683	Conserved Protein
LU294_02595	COG3708	Transcriptional regulator
LU294_02605	COG1252	NADH dehydrogenase
LU294_02620	COG3584	3D domain protein
LU294_02635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LU294_02640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LU294_02645	COG1268	BioY protein
LU294_02655	COG2050	protein possibly involved in aromatic compounds catabolism
LU294_02675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LU294_02680	COG5018	Exonuclease
LU294_02700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LU294_02710	COG2267	carboxylic ester hydrolase activity
LU294_02715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LU294_02720	COG1522	sequence-specific DNA binding
LU294_02725	COG0436	Aminotransferase
LU294_02730	COG1098	S1 RNA binding domain
LU294_02735	COG2155	Conserved Protein
LU294_02750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LU294_02755	COG1285	pathogenesis
LU294_02790	COG0544	peptidyl-prolyl cis-trans isomerase activity
LU294_02890	COG1404	Belongs to the peptidase S8 family
LU294_02910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LU294_02920	COG0058	SHG alpha-glucan phosphorylase activity
LU294_02940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LU294_02945	COG1575	Belongs to the MenA family. Type 1 subfamily
LU294_02950	COG1169	isochorismate synthase
LU294_02960	COG0596	Alpha beta hydrolase
LU294_02965	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LU294_02975	COG4948	Mandelate Racemase Muconate Lactonizing
LU294_03000	COG3964	amidohydrolase
LU294_03020	COG2188	Transcriptional regulator
LU294_03050	COG0577	efflux transmembrane transporter activity
LU294_03055	COG1136	(ABC) transporter
LU294_03060	COG0577	efflux transmembrane transporter activity
LU294_03065	COG0577	efflux transmembrane transporter activity
LU294_03070	COG2205	protein histidine kinase activity
LU294_03075	COG0745	RESPONSE REGULATOR receiver
LU294_03080	COG0640	Transcriptional regulator
LU294_03085	COG5658	integral membrane protein
LU294_03090	COG2207	Transcriptional regulator
LU294_03090	COG3708	Transcriptional regulator
LU294_03095	COG1136	(ABC) transporter
LU294_03100	COG0577	efflux transmembrane transporter activity
LU294_03110	COG4977	sequence-specific DNA binding
LU294_03120	COG0586	Pfam SNARE associated Golgi protein
LU294_03145	COG1136	(ABC) transporter
LU294_03150	COG0577	efflux transmembrane transporter activity
LU294_03165	COG1597	lipid kinase activity
LU294_03170	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LU294_03195	COG0745	RESPONSE REGULATOR receiver
LU294_03200	COG5002	protein histidine kinase activity
LU294_03270	COG1842	Phage shock protein A
LU294_03295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LU294_03315	COG1294	oxidase, subunit
LU294_03320	COG1271	oxidase subunit
LU294_03325	COG0288	reversible hydration of carbon dioxide
LU294_03360	COG0494	nUDIX hydrolase
LU294_03380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LU294_03400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LU294_03405	COG1116	anion transmembrane transporter activity
LU294_03410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LU294_03435	COG1368	sulfuric ester hydrolase activity
LU294_03440	COG2267	carboxylic ester hydrolase activity
LU294_03445	COG4191	Histidine kinase
LU294_03450	COG5002	protein histidine kinase activity
LU294_03460	COG1349	DNA-binding transcription factor activity
LU294_03465	COG0546	phosphoglycolate phosphatase activity
LU294_03470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LU294_03530	COG0521	Mo-molybdopterin cofactor biosynthetic process
LU294_03540	COG0438	transferase activity, transferring glycosyl groups
LU294_03545	COG0671	phosphoesterase, PA-phosphatase related
LU294_03550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LU294_03555	COG2267	carboxylic ester hydrolase activity
LU294_03580	COG1794	racemase activity, acting on amino acids and derivatives
LU294_03595	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LU294_03600	COG1242	4 iron, 4 sulfur cluster binding
LU294_03620	COG1136	(ABC) transporter
LU294_03630	COG0582	viral genome integration into host DNA
LU294_03635	COG0490	domain, Protein
LU294_03640	COG0475	glutathione-regulated potassium exporter activity
LU294_03645	COG2814	Major facilitator Superfamily
LU294_03685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LU294_03695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LU294_03730	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LU294_03735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LU294_03745	COG0303	'Molybdopterin
LU294_03750	COG1763	Mo-molybdopterin cofactor biosynthetic process
LU294_03755	COG0314	molybdopterin synthase activity
LU294_03780	COG1329	Transcriptional regulator
LU294_03800	COG3832	glyoxalase III activity
LU294_03810	COG2814	Major facilitator Superfamily
LU294_03815	COG2081	HI0933 family
LU294_03820	COG2244	polysaccharide biosynthetic process
LU294_03825	COG1187	pseudouridine synthase activity
LU294_03830	COG1349	DNA-binding transcription factor activity
LU294_03835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LU294_03845	COG1523	belongs to the glycosyl hydrolase 13 family
LU294_03850	COG0510	thiamine kinase activity
LU294_03865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LU294_03875	COG1363	Peptidase, m42
LU294_03880	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LU294_03885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LU294_03895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LU294_03905	COG1674	ftsk spoiiie
LU294_03925	COG1695	Transcriptional regulator
LU294_03930	COG0789	Transcriptional regulator
LU294_03935	COG0697	spore germination
LU294_03940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LU294_03955	COG2309	aminopeptidase activity
LU294_03965	COG3118	belongs to the thioredoxin family
LU294_03970	COG4851	CamS sex pheromone cAM373 precursor
LU294_03975	COG1609	Transcriptional regulator
LU294_04030	COG0745	RESPONSE REGULATOR receiver
LU294_04030	COG2972	Histidine kinase
LU294_04035	COG0666	response to abiotic stimulus
LU294_04045	COG0745	RESPONSE REGULATOR receiver
LU294_04060	COG0123	including yeast histone deacetylase and acetoin utilization protein
LU294_04065	COG0517	IMP dehydrogenase activity
LU294_04070	COG0454	-acetyltransferase
LU294_04075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LU294_04085	COG1595	DNA-templated transcription, initiation
LU294_04115	COG0626	cystathionine gamma-synthase activity
LU294_04120	COG1956	GAF domain-containing protein
LU294_04125	COG1309	transcriptional regulator
LU294_04130	COG0697	spore germination
LU294_04135	COG0583	DNA-binding transcription factor activity
LU294_04145	COG1104	cysteine desulfurase activity
LU294_04160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LU294_04170	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LU294_04185	COG3874	Sporulation protein YtfJ
LU294_04190	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LU294_04195	COG0827	DNA restriction-modification system
LU294_04220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LU294_04265	COG0589	response to stress
LU294_04270	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_04315	COG0662	Cupin 2, conserved barrel domain protein
LU294_04355	COG0006	proline dipeptidase activity
LU294_04370	COG4109	DRTGG domain
LU294_04380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LU294_04395	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LU294_04410	COG0587	DNA-directed DNA polymerase activity
LU294_04415	COG0281	malic enzyme
LU294_04420	COG1725	Transcriptional regulator
LU294_04445	COG3030	protein affecting phage T7 exclusion by the F plasmid
LU294_04450	COG0628	permease
LU294_04460	COG0372	Belongs to the citrate synthase family
LU294_04465	COG0538	isocitrate dehydrogenase activity
LU294_04485	COG0745	RESPONSE REGULATOR receiver
LU294_04490	COG5002	protein histidine kinase activity
LU294_04495	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LU294_04495	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LU294_04505	COG1971	Probably functions as a manganese efflux pump
LU294_04510	COG0237	dephospho-CoA kinase activity
LU294_04515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LU294_04520	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LU294_04530	COG3611	Membrane attachment protein
LU294_04535	COG1484	DNA-dependent DNA replication
LU294_04545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LU294_04570	COG1363	Peptidase, m42
LU294_04575	COG1309	transcriptional regulator
LU294_04580	COG1566	PFAM secretion protein HlyD family protein
LU294_04585	COG2814	Major facilitator Superfamily
LU294_04595	COG1418	mRNA catabolic process
LU294_04605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LU294_04650	COG1286	toxin biosynthetic process
LU294_04655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LU294_04655	COG1796	DNA polymerase
LU294_04665	COG1187	pseudouridine synthase activity
LU294_04670	COG1114	Component of the transport system for branched-chain amino acids
LU294_04675	COG5386	Cell surface protein
LU294_04680	COG5386	Cell surface protein
LU294_04695	COG1120	ATPase activity
LU294_04700	COG4509	Sortase family
LU294_04715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LU294_04720	COG4895	conserved protein (DUF2196)
LU294_04730	COG0745	RESPONSE REGULATOR receiver
LU294_04735	COG2205	protein histidine kinase activity
LU294_04740	COG1131	(ABC) transporter
LU294_04765	COG2318	DinB family
LU294_04780	COG0318	PFAM AMP-dependent synthetase and ligase
LU294_04785	COG1309	transcriptional regulator
LU294_04790	COG1024	Enoyl-CoA hydratase
LU294_04795	COG2086	electron transfer activity
LU294_04800	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LU294_04805	COG3118	belongs to the thioredoxin family
LU294_04815	COG1719	4-vinyl reductase, 4VR
LU294_04820	COG2009	succinate dehydrogenase
LU294_04825	COG1053	succinate dehydrogenase
LU294_04830	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LU294_04835	COG0824	Thioesterase
LU294_04840	COG1876	peptidase activity
LU294_04845	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LU294_04850	COG1360	Flagellar Motor Protein
LU294_04855	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LU294_04860	COG4152	abc transporter atp-binding protein
LU294_04865	COG1668	transmembrane transport
LU294_04870	COG1959	2 iron, 2 sulfur cluster binding
LU294_04880	COG0697	spore germination
LU294_04885	COG1396	sequence-specific DNA binding
LU294_04890	COG1983	PspC domain protein
LU294_04900	COG3279	Response regulator of the LytR AlgR family
LU294_04905	COG3275	phosphorelay sensor kinase activity
LU294_04910	COG4608	Belongs to the ABC transporter superfamily
LU294_04915	COG0444	Belongs to the ABC transporter superfamily
LU294_04925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LU294_04935	COG0402	S-adenosylhomocysteine deaminase activity
LU294_04940	COG0402	S-adenosylhomocysteine deaminase activity
LU294_04950	COG2233	PERMEase
LU294_04955	COG2197	response regulator
LU294_04965	COG1309	transcriptional regulator
LU294_04975	COG2814	Major facilitator Superfamily
LU294_04985	COG5401	PFAM Sporulation and spore germination
LU294_05000	COG0622	Phosphoesterase
LU294_05045	COG0470	DNA polymerase III
LU294_05045	COG1067	ATP-dependent peptidase activity
LU294_05060	COG1764	response to oxidative stress
LU294_05065	COG1846	Transcriptional regulator
LU294_05075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LU294_05085	COG1587	Uroporphyrinogen-III synthase
LU294_05090	COG0113	porphobilinogen synthase activity
LU294_05100	COG1388	LysM domain
LU294_05115	COG0285	dihydrofolate synthase activity
LU294_05135	COG1077	Cell shape determining protein MreB Mrl
LU294_05155	COG2894	cell division
LU294_05160	COG0739	heme binding
LU294_05165	COG1994	Peptidase M50
LU294_05170	COG1530	ribonuclease E activity
LU294_05175	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LU294_05180	COG2868	ribosomal protein
LU294_05190	COG3290	protein histidine kinase activity
LU294_05200	COG0745	RESPONSE REGULATOR receiver
LU294_05205	COG5002	protein histidine kinase activity
LU294_05210	COG1136	(ABC) transporter
LU294_05215	COG0577	efflux transmembrane transporter activity
LU294_05220	COG0577	efflux transmembrane transporter activity
LU294_05225	COG0077	Prephenate dehydratase
LU294_05230	COG2258	MOSC domain
LU294_05235	COG1827	regulation of RNA biosynthetic process
LU294_05240	COG1104	cysteine desulfurase activity
LU294_05245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LU294_05250	COG0157	Belongs to the NadC ModD family
LU294_05275	COG0640	Transcriptional regulator
LU294_05280	COG0697	spore germination
LU294_05290	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LU294_05320	COG1862	Preprotein translocase
LU294_05330	COG2323	membrane
LU294_05335	COG2244	polysaccharide biosynthetic process
LU294_05345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LU294_05345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LU294_05350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LU294_05355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LU294_05355	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LU294_05365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LU294_05390	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LU294_05400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LU294_05405	COG1959	2 iron, 2 sulfur cluster binding
LU294_05410	COG1104	cysteine desulfurase activity
LU294_05425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LU294_05445	COG0628	permease
LU294_05475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LU294_05480	COG4122	O-methyltransferase activity
LU294_05485	COG0826	peptidase U32
LU294_05490	COG0826	peptidase U32
LU294_05505	COG0768	penicillin binding
LU294_05530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LU294_05535	COG0626	cystathionine gamma-synthase activity
LU294_05540	COG1012	belongs to the aldehyde dehydrogenase family
LU294_05540	COG1454	alcohol dehydrogenase
LU294_05550	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LU294_05590	COG2259	Doxx family
LU294_05595	COG2514	catechol 2,3-dioxygenase activity
LU294_05605	COG3186	Phenylalanine-4-hydroxylase
LU294_05610	COG1404	Belongs to the peptidase S8 family
LU294_05645	COG2267	carboxylic ester hydrolase activity
LU294_05655	COG1785	Belongs to the alkaline phosphatase family
LU294_05665	COG2357	RelA SpoT domain protein
LU294_05670	COG0778	Nitroreductase
LU294_05705	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LU294_05710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LU294_05720	COG1534	Rna-binding protein
LU294_05730	COG1713	HD superfamily hydrolase involved in NAD metabolism
LU294_05735	COG0799	negative regulation of ribosome biogenesis
LU294_05740	COG2226	methyltransferase
LU294_05745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LU294_05750	COG1555	photosystem II stabilization
LU294_05750	COG1596	polysaccharide export
LU294_05755	COG2131	deaminase
LU294_05760	COG0658	competence protein
LU294_05760	COG2333	competence protein COMEC
LU294_05770	COG1466	dna polymerase III delta subunit
LU294_05795	COG1733	regulation of RNA biosynthetic process
LU294_05800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LU294_05830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LU294_05835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LU294_05840	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LU294_05845	COG1610	YqeY-like protein
LU294_05860	COG1702	phosphate starvation-inducible protein PhoH
LU294_05865	COG1480	7TM receptor with intracellular HD hydrolase
LU294_05875	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LU294_05880	COG0295	cytidine deaminase activity
LU294_05885	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LU294_05900	COG0517	IMP dehydrogenase activity
LU294_05910	COG0358	DNA primase activity
LU294_05915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LU294_05920	COG2010	Cytochrome c
LU294_05925	COG2384	SAM-dependent methyltransferase
LU294_05930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LU294_05960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LU294_05965	COG1121	(ABC) transporter
LU294_05970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LU294_05975	COG0735	belongs to the Fur family
LU294_06000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LU294_06005	COG0477	Major facilitator Superfamily
LU294_06010	COG0768	penicillin binding
LU294_06015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LU294_06020	COG0573	inorganic phosphate transmembrane transporter activity
LU294_06025	COG0581	inorganic phosphate transmembrane transporter activity
LU294_06035	COG0704	Plays a role in the regulation of phosphate uptake
LU294_06040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LU294_06045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LU294_06050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LU294_06055	COG4483	Protein conserved in bacteria
LU294_06060	COG1940	carbohydrate kinase activity
LU294_06070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LU294_06090	COG0626	cystathionine gamma-synthase activity
LU294_06095	COG0626	cystathionine gamma-synthase activity
LU294_06100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LU294_06100	COG0646	methionine synthase
LU294_06105	COG1410	methionine synthase
LU294_06105	COG0646	methionine synthase
LU294_06155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LU294_06160	COG1459	type II secretion system
LU294_06170	COG4970	Tfp pilus assembly protein FimT
LU294_06225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LU294_06255	COG1725	Transcriptional regulator
LU294_06260	COG1131	(ABC) transporter
LU294_06300	COG2076	Multidrug Resistance protein
LU294_06305	COG2076	Multidrug Resistance protein
LU294_06315	COG1609	Transcriptional regulator
LU294_06320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LU294_06325	COG0095	Lipoate-protein ligase
LU294_06345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LU294_06355	COG3872	metal-dependent enzyme
LU294_06370	COG0006	proline dipeptidase activity
LU294_06395	COG3854	ATPases associated with a variety of cellular activities
LU294_06440	COG0511	ligase activity, forming carbon-carbon bonds
LU294_06445	COG0439	Biotin carboxylase
LU294_06450	COG1302	Protein conserved in bacteria
LU294_06475	COG0142	geranyltranstransferase activity
LU294_06485	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LU294_06495	COG0497	DNA recombination
LU294_06500	COG0750	zinc metalloprotease
LU294_06505	COG0745	RESPONSE REGULATOR receiver
LU294_06595	COG3093	addiction module antidote protein HigA
LU294_06600	COG0584	glycerophosphoryl diester phosphodiesterase
LU294_06610	COG3829	transcription factor binding
LU294_06610	COG3290	protein histidine kinase activity
LU294_06615	COG0280	phosphate acetyltransferase
LU294_06630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LU294_06635	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LU294_06640	COG0022	dehydrogenase e1 component
LU294_06645	COG0508	dehydrogenase complex catalyzes the overall conversion of
LU294_06650	COG0772	Belongs to the SEDS family
LU294_06655	COG2323	membrane
LU294_06670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LU294_06675	COG0765	amino acid transport
LU294_06680	COG1126	abc transporter atp-binding protein
LU294_06685	COG4129	membrane
LU294_06690	COG1376	ErfK ybiS ycfS ynhG family protein
LU294_06705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LU294_06710	COG2195	Cleaves the N-terminal amino acid of tripeptides
LU294_06725	COG1285	pathogenesis
LU294_06750	COG1760	l-serine dehydratase
LU294_06755	COG1760	l-serine dehydratase
LU294_06760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LU294_06765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LU294_06770	COG0300	oxidoreductase activity
LU294_06795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LU294_06815	COG1522	sequence-specific DNA binding
LU294_06825	COG0737	Belongs to the 5'-nucleotidase family
LU294_06830	COG1757	Na H antiporter
LU294_06840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LU294_06855	COG1073	alpha beta
LU294_06855	COG2226	methyltransferase
LU294_06860	COG4106	trans-aconitate 2-methyltransferase activity
LU294_06885	COG0307	riboflavin synthase, alpha
LU294_06890	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LU294_06890	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LU294_06905	COG1073	alpha beta
LU294_06910	COG0456	acetyltransferase
LU294_06915	COG1609	Transcriptional regulator
LU294_06920	COG2056	Na+-H+ antiporter family
LU294_06925	COG0596	Alpha beta hydrolase
LU294_06935	COG0737	Belongs to the 5'-nucleotidase family
LU294_06935	COG4085	toxin activity
LU294_06935	COG1525	nuclease
LU294_06945	COG0456	acetyltransferase
LU294_06945	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LU294_06950	COG0656	L-ascorbic acid biosynthetic process
LU294_06955	COG0667	Aldo Keto reductase
LU294_06975	COG1300	Membrane
LU294_06980	COG0735	belongs to the Fur family
LU294_06990	COG4974	Belongs to the 'phage' integrase family
LU294_07015	COG0598	Magnesium transport protein CorA
LU294_07030	COG1846	Transcriptional regulator
LU294_07050	COG1131	(ABC) transporter
LU294_07055	COG1725	Transcriptional regulator
LU294_07060	COG1686	Belongs to the peptidase S11 family
LU294_07080	COG0733	neurotransmitter:sodium symporter activity
LU294_07105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LU294_07120	COG0697	spore germination
LU294_07125	COG0561	phosphatase activity
LU294_07130	COG4086	secreted protein
LU294_07135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LU294_07140	COG0456	acetyltransferase
LU294_07145	COG1547	Domain of unknown function (DUF309)
LU294_07170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LU294_07185	COG2188	Transcriptional regulator
LU294_07195	COG3711	transcriptional antiterminator
LU294_07200	COG1263	PTS System
LU294_07200	COG2190	(PTS) system
LU294_07200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LU294_07225	COG0778	Nitroreductase
LU294_07230	COG2199	diguanylate cyclase activity
LU294_07240	COG2084	Dehydrogenase
LU294_07275	COG0436	Aminotransferase
LU294_07280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LU294_07300	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_07305	COG1695	Transcriptional regulator
LU294_07340	COG0183	Belongs to the thiolase family
LU294_07345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LU294_07385	COG3842	ATPase activity
LU294_07390	COG0366	Alpha amylase catalytic
LU294_07400	COG2182	Extracellular solute-binding protein
LU294_07405	COG1175	transmembrane transport
LU294_07410	COG3833	ABC-type maltose transport systems, permease component
LU294_07415	COG1609	Transcriptional regulator
LU294_07420	COG0436	Aminotransferase
LU294_07430	COG2205	protein histidine kinase activity
LU294_07440	COG3209	COG3209 Rhs family protein
LU294_07465	COG2814	Major facilitator Superfamily
LU294_07500	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LU294_07510	COG1408	metallophosphoesterase
LU294_07515	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_07520	COG2200	EAL domain
LU294_07535	COG4703	Protein of unknown function (DUF1797)
LU294_07545	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LU294_07555	COG0517	IMP dehydrogenase activity
LU294_07560	COG0583	DNA-binding transcription factor activity
LU294_07580	COG0569	domain protein
LU294_07585	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LU294_07595	COG0561	phosphatase activity
LU294_07600	COG0242	peptide deformylase activity
LU294_07610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LU294_07615	COG0022	dehydrogenase e1 component
LU294_07660	COG1982	Orn Lys Arg decarboxylase major
LU294_07680	COG0483	inositol monophosphate 1-phosphatase activity
LU294_07690	COG1217	gtp-binding protein TYPA
LU294_07705	COG4896	Protein conserved in bacteria
LU294_07715	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LU294_07720	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LU294_07730	COG0772	Belongs to the SEDS family
LU294_07735	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LU294_07755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LU294_07770	COG3336	cytochrome c oxidase
LU294_07785	COG2340	Cysteine-rich secretory protein family
LU294_07800	COG0406	alpha-ribazole phosphatase activity
LU294_07805	COG3679	Belongs to the UPF0342 family
LU294_07820	COG0742	ribosomal rna small subunit methyltransferase
LU294_07830	COG3314	Sporulation integral membrane protein YlbJ
LU294_07835	COG1752	Esterase of the alpha-beta hydrolase superfamily
LU294_07840	COG3480	Lon protease (S16) C-terminal proteolytic domain
LU294_07850	COG1399	metal-binding, possibly nucleic acid-binding protein
LU294_07855	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LU294_07870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LU294_07885	COG4839	cell division protein FtsL
LU294_07890	COG0768	penicillin binding
LU294_07895	COG0768	penicillin binding
LU294_07900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LU294_07915	COG0772	Belongs to the SEDS family
LU294_07930	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LU294_07935	COG0849	cell division
LU294_07940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LU294_07950	COG1191	sigma factor activity
LU294_07955	COG1191	sigma factor activity
LU294_07960	COG1873	PFAM PRC-barrel domain
LU294_07970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LU294_07980	COG0762	integral membrane protein
LU294_07985	COG2302	S4 RNA-binding domain
LU294_07990	COG3599	regulation of cell shape
LU294_08010	COG0564	pseudouridine synthase activity
LU294_08070	COG3069	C4-dicarboxylate transmembrane transporter activity
LU294_08090	COG0006	proline dipeptidase activity
LU294_08105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LU294_08110	COG1561	YicC-like family, N-terminal region
LU294_08130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LU294_08135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LU294_08140	COG0242	peptide deformylase activity
LU294_08150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LU294_08150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LU294_08160	COG0631	protein serine/threonine phosphatase activity
LU294_08165	COG2815	serine threonine protein kinase
LU294_08165	COG0515	serine threonine protein kinase
LU294_08175	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LU294_08180	COG1564	THIamine pyrophosphokinase
LU294_08195	COG1302	Protein conserved in bacteria
LU294_08200	COG1461	Dihydroxyacetone kinase
LU294_08205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LU294_08220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LU294_08225	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_08230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LU294_08240	COG1196	nuclear chromosome segregation
LU294_08245	COG0552	protein localization to endoplasmic reticulum
LU294_08255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LU294_08265	COG1837	Belongs to the UPF0109 family
LU294_08305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LU294_08310	COG0758	DNA mediated transformation
LU294_08315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LU294_08325	COG4974	Belongs to the 'phage' integrase family
LU294_08355	COG0528	UMP kinase activity
LU294_08370	COG4589	Belongs to the CDS family
LU294_08380	COG0750	zinc metalloprotease
LU294_08400	COG0195	Participates in both transcription termination and antitermination
LU294_08405	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LU294_08410	COG1358	cellular component organization or biogenesis
LU294_08420	COG1550	Protein conserved in bacteria
LU294_08435	COG0196	riboflavin kinase activity
LU294_08450	COG0726	polysaccharide deacetylase
LU294_08455	COG0612	Peptidase, M16
LU294_08460	COG1873	PFAM PRC-barrel domain
LU294_08465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LU294_08470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LU294_08475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LU294_08480	COG0527	aspartate kinase activity
LU294_08490	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LU294_08495	COG0740	serine-type endopeptidase activity
LU294_08505	COG1674	ftsk spoiiie
LU294_08510	COG2188	Transcriptional regulator
LU294_08515	COG1744	ABC transporter substrate-binding protein PnrA-like
LU294_08520	COG3845	ABC transporter
LU294_08525	COG4603	Belongs to the binding-protein-dependent transport system permease family
LU294_08530	COG1079	Belongs to the binding-protein-dependent transport system permease family
LU294_08535	COG0612	Peptidase, M16
LU294_08540	COG0612	Peptidase, M16
LU294_08545	COG0300	oxidoreductase activity
LU294_08560	COG1426	Protein conserved in bacteria
LU294_08565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LU294_08585	COG1418	mRNA catabolic process
LU294_08590	COG1692	metallophosphoesterase
LU294_08595	COG2359	stage V sporulation protein S
LU294_08605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LU294_08605	COG0674	pyruvate-flavodoxin oxidoreductase activity
LU294_08610	COG1013	pyruvate-flavodoxin oxidoreductase activity
LU294_08620	COG4550	Control of competence regulator ComK, YlbF/YmcA
LU294_08645	COG1131	(ABC) transporter
LU294_08670	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LU294_08680	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LU294_08685	COG1368	sulfuric ester hydrolase activity
LU294_08695	COG3773	Cell wall hydrolase
LU294_08700	COG1404	Belongs to the peptidase S8 family
LU294_08720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LU294_08725	COG1380	Effector of murein hydrolase LrgA
LU294_08730	COG1346	cytolysis
LU294_08740	COG0384	phenazine biosynthesis protein PhzF
LU294_08775	COG3300	MHYT domain
LU294_08775	COG5001	Diguanylate cyclase
LU294_08780	COG0346	lactoylglutathione lyase activity
LU294_08785	COG2267	carboxylic ester hydrolase activity
LU294_08800	COG2364	Membrane
LU294_08810	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LU294_08815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LU294_08820	COG2169	Transcriptional regulator
LU294_08825	COG0708	Exodeoxyribonuclease III
LU294_08830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LU294_08835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LU294_08840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LU294_08845	COG1120	ATPase activity
LU294_08850	COG2819	hydrolase of the alpha beta superfamily
LU294_08870	COG1230	cation diffusion facilitator family transporter
LU294_08880	COG1937	Protein conserved in bacteria
LU294_08885	COG2608	mercury ion transmembrane transporter activity
LU294_08890	COG2217	Heavy metal translocating P-type atpase
LU294_08905	COG2116	formate transmembrane transporter activity
LU294_08910	COG1408	metallophosphoesterase
LU294_08920	COG1113	amino acid transport
LU294_08930	COG2322	membrane
LU294_08935	COG1979	alcohol dehydrogenase
LU294_08940	COG1349	DNA-binding transcription factor activity
LU294_08945	COG1105	Belongs to the carbohydrate kinase PfkB family
LU294_08950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LU294_08950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LU294_08950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LU294_08955	COG3584	3D domain protein
LU294_08955	COG1388	LysM domain
LU294_08985	COG0464	growth
LU294_08990	COG2860	membrane
LU294_08995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LU294_09000	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LU294_09005	COG0789	Transcriptional regulator
LU294_09010	COG0174	glutamine synthetase
LU294_09015	COG1695	Transcriptional regulator
LU294_09035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LU294_09045	COG0737	Belongs to the 5'-nucleotidase family
LU294_09050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LU294_09055	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LU294_09060	COG3639	organic phosphonate transmembrane transporter activity
LU294_09085	COG1132	(ABC) transporter
LU294_09090	COG1132	(ABC) transporter
LU294_09110	COG5632	N-Acetylmuramoyl-L-alanine amidase
LU294_09110	COG3409	Peptidoglycan-binding domain 1 protein
LU294_09120	COG0730	response to heat
LU294_09135	COG1346	cytolysis
LU294_09145	COG0583	DNA-binding transcription factor activity
LU294_09155	COG1131	(ABC) transporter
LU294_09165	COG1473	amidohydrolase
LU294_09175	COG0785	Cytochrome C biogenesis protein
LU294_09180	COG4846	Membrane protein involved in cytochrome C biogenesis
LU294_09215	COG2226	methyltransferase
LU294_09240	COG0010	Belongs to the arginase family
LU294_09245	COG1329	Transcriptional regulator
LU294_09250	COG1902	pentaerythritol trinitrate reductase activity
LU294_09255	COG0069	glutamate synthase activity
LU294_09265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LU294_09270	COG0346	lactoylglutathione lyase activity
LU294_09275	COG0400	carboxylic ester hydrolase activity
LU294_09280	COG5002	protein histidine kinase activity
LU294_09290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LU294_09340	COG1396	sequence-specific DNA binding
LU294_09355	COG0318	PFAM AMP-dependent synthetase and ligase
LU294_09360	COG1268	BioY protein
LU294_09365	COG0318	PFAM AMP-dependent synthetase and ligase
LU294_09370	COG0183	Belongs to the thiolase family
LU294_09385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LU294_09395	COG2211	Major facilitator Superfamily
LU294_09425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LU294_09430	COG1132	(ABC) transporter
LU294_09440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LU294_09470	COG0824	Thioesterase
LU294_09475	COG4841	protein insertion into membrane
LU294_09495	COG0745	RESPONSE REGULATOR receiver
LU294_09500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LU294_09505	COG1832	CoA-binding protein
LU294_09510	COG0187	DNA topoisomerase II activity
LU294_09515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LU294_09520	COG0673	inositol 2-dehydrogenase activity
LU294_09530	COG1131	(ABC) transporter
LU294_09540	COG0346	lactoylglutathione lyase activity
LU294_09545	COG1595	DNA-templated transcription, initiation
LU294_09555	COG1316	TRANSCRIPTIONal
LU294_09560	COG1301	dicarboxylic acid transport
LU294_09565	COG4166	transmembrane transport
LU294_09570	COG4166	transmembrane transport
LU294_09575	COG4166	transmembrane transport
LU294_09580	COG2226	methyltransferase
LU294_09625	COG0697	spore germination
LU294_09630	COG3383	formate dehydrogenase (NAD+) activity
LU294_09635	COG2427	Protein of unknown function (DUF1641)
LU294_09640	COG5609	conserved protein (DUF2294)
LU294_09645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LU294_09655	COG2116	formate transmembrane transporter activity
LU294_09660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LU294_09665	COG0303	'Molybdopterin
LU294_09670	COG0314	molybdopterin synthase activity
LU294_09680	COG0489	protein tyrosine kinase activity
LU294_09695	COG3326	Membrane
LU294_09700	COG2962	Rard protein
LU294_09705	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LU294_09710	COG1657	PFAM Prenyltransferase squalene oxidase
LU294_09720	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_09725	COG1012	belongs to the aldehyde dehydrogenase family
LU294_09735	COG4145	pantothenate transmembrane transporter activity
LU294_09750	COG0165	Argininosuccinate lyase
LU294_09760	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_09780	COG0494	nUDIX hydrolase
LU294_09790	COG0716	FMN binding
LU294_09825	COG2720	vancomycin resistance protein
LU294_09830	COG2514	catechol 2,3-dioxygenase activity
LU294_09845	COG1285	pathogenesis
LU294_09880	COG0277	FAD linked oxidase domain protein
LU294_09885	COG0385	Bile acid
LU294_09895	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LU294_09910	COG0457	Tetratricopeptide repeat
LU294_09920	COG0604	alcohol dehydrogenase
LU294_09925	COG0640	Transcriptional regulator
LU294_09930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LU294_09945	COG0584	glycerophosphoryl diester phosphodiesterase
LU294_09975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LU294_09980	COG1164	Oligoendopeptidase f
LU294_09985	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LU294_09990	COG1193	negative regulation of DNA recombination
LU294_10005	COG2890	protein-(glutamine-N5) methyltransferase activity
LU294_10015	COG0583	DNA-binding transcription factor activity
LU294_10050	COG3739	integral membrane protein
LU294_10055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LU294_10060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LU294_10065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LU294_10080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LU294_10085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LU294_10110	COG2814	Major facilitator Superfamily
LU294_10115	COG1113	amino acid transport
LU294_10125	COG1695	Transcriptional regulator
LU294_10170	COG2072	flavoprotein involved in K transport
LU294_10200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LU294_10210	COG1151	hydroxylamine reductase activity
LU294_10255	COG1309	transcriptional regulator
LU294_10275	COG1191	sigma factor activity
LU294_10300	COG1733	regulation of RNA biosynthetic process
LU294_10305	COG2249	NAD(P)H dehydrogenase (quinone) activity
LU294_10310	COG0318	PFAM AMP-dependent synthetase and ligase
LU294_10330	COG0384	phenazine biosynthesis protein PhzF
LU294_10350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LU294_10375	COG1733	regulation of RNA biosynthetic process
LU294_10380	COG1733	regulation of RNA biosynthetic process
LU294_10385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LU294_10390	COG0673	inositol 2-dehydrogenase activity
LU294_10395	COG2188	Transcriptional regulator
LU294_10400	COG1733	regulation of RNA biosynthetic process
LU294_10405	COG1393	Belongs to the ArsC family
LU294_10430	COG0814	amino acid
LU294_10435	COG0346	lactoylglutathione lyase activity
LU294_10450	COG2814	Major facilitator Superfamily
LU294_10455	COG0656	L-ascorbic acid biosynthetic process
LU294_10470	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_10475	COG0604	alcohol dehydrogenase
LU294_10475	COG3321	synthase
LU294_10485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LU294_10490	COG0604	alcohol dehydrogenase
LU294_10495	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LU294_10500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LU294_10510	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LU294_10515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LU294_10525	COG1070	Carbohydrate kinase
LU294_10530	COG2706	6-phosphogluconolactonase activity
LU294_10535	COG3813	Protein conserved in bacteria
LU294_10540	COG1357	PFAM Pentapeptide repeats (8 copies)
LU294_10545	COG0697	spore germination
LU294_10585	COG0789	Transcriptional regulator
LU294_10590	COG1253	flavin adenine dinucleotide binding
LU294_10615	COG0477	Major facilitator Superfamily
LU294_10625	COG0500	methyltransferase
LU294_10645	COG0628	permease
LU294_10660	COG0110	maltose O-acetyltransferase activity
LU294_10665	COG1940	carbohydrate kinase activity
LU294_10670	COG0346	lactoylglutathione lyase activity
LU294_10695	COG2365	Tyrosine phosphatase family
LU294_10705	COG1011	Hydrolase
LU294_10730	COG1131	(ABC) transporter
LU294_10740	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_10780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LU294_10825	COG1288	antiporter activity
LU294_10830	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LU294_10845	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LU294_10880	COG2249	NAD(P)H dehydrogenase (quinone) activity
LU294_10890	COG2031	fatty acid transporter
LU294_10900	COG1309	transcriptional regulator
LU294_10905	COG2076	Multidrug Resistance protein
LU294_10925	COG1131	(ABC) transporter
LU294_10930	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LU294_10940	COG2814	Major facilitator Superfamily
LU294_10945	COG1846	Transcriptional regulator
LU294_10960	COG0477	Major facilitator Superfamily
LU294_10990	COG5632	N-Acetylmuramoyl-L-alanine amidase
LU294_10990	COG3409	Peptidoglycan-binding domain 1 protein
LU294_11010	COG2207	Transcriptional regulator
LU294_11010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LU294_11015	COG0662	Cupin 2, conserved barrel domain protein
LU294_11035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LU294_11050	COG1619	proteins homologs of microcin C7 resistance protein MccF
LU294_11065	COG0583	DNA-binding transcription factor activity
LU294_11075	COG1139	Iron-sulfur cluster binding protein
LU294_11080	COG1556	Lactate utilization protein
LU294_11085	COG2271	Major facilitator Superfamily
LU294_11090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LU294_11095	COG2808	Putative FMN-binding domain
LU294_11100	COG0456	acetyltransferase
LU294_11105	COG1846	Transcriptional regulator
LU294_11110	COG2364	Membrane
LU294_11120	COG3850	Histidine kinase
LU294_11120	COG5002	protein histidine kinase activity
LU294_11140	COG0577	efflux transmembrane transporter activity
LU294_11160	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LU294_11175	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LU294_11225	COG4895	conserved protein (DUF2196)
LU294_11235	COG2814	Major facilitator Superfamily
LU294_11265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LU294_11290	COG0346	lactoylglutathione lyase activity
LU294_11305	COG1522	sequence-specific DNA binding
LU294_11345	COG1309	transcriptional regulator
LU294_11350	COG2814	Major facilitator Superfamily
LU294_11365	COG1309	transcriptional regulator
LU294_11370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LU294_11370	COG3320	Male sterility
LU294_11380	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LU294_11390	COG0640	Transcriptional regulator
LU294_11395	COG0346	lactoylglutathione lyase activity
LU294_11400	COG0798	PFAM Bile acid sodium symporter
LU294_11430	COG0577	efflux transmembrane transporter activity
LU294_11435	COG1136	(ABC) transporter
LU294_11440	COG4641	Protein conserved in bacteria
LU294_11445	COG2267	carboxylic ester hydrolase activity
LU294_11455	COG1575	Belongs to the MenA family. Type 1 subfamily
LU294_11465	COG0697	spore germination
LU294_11480	COG5609	conserved protein (DUF2294)
LU294_11485	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LU294_11495	COG0288	reversible hydration of carbon dioxide
LU294_11525	COG0583	DNA-binding transcription factor activity
LU294_11535	COG1309	transcriptional regulator
LU294_11575	COG0598	Magnesium transport protein CorA
LU294_11585	COG0753	catalase activity
LU294_11590	COG0737	Belongs to the 5'-nucleotidase family
LU294_11595	COG0531	amino acid
LU294_11605	COG0534	Mate efflux family protein
LU294_11610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LU294_11610	COG0723	plastoquinol--plastocyanin reductase activity
LU294_11620	COG3961	Belongs to the TPP enzyme family
LU294_11630	COG1063	alcohol dehydrogenase
LU294_11660	COG1113	amino acid transport
LU294_11665	COG1280	lysine exporter protein (LysE YggA)
LU294_11670	COG3403	YqcI/YcgG family
LU294_11675	COG5577	PFAM Coat F domain
LU294_11690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LU294_11700	COG0574	Belongs to the PEP-utilizing enzyme family
LU294_11700	COG3848	Pyruvate phosphate dikinase
LU294_11705	COG1309	transcriptional regulator
LU294_11725	COG3314	Sporulation integral membrane protein YlbJ
LU294_11740	COG1960	acyl-CoA dehydrogenase activity
LU294_11755	COG0640	Transcriptional regulator
LU294_11760	COG0860	N-Acetylmuramoyl-L-alanine amidase
LU294_11765	COG3142	Participates in the control of copper homeostasis
LU294_11775	COG1414	Transcriptional regulator
LU294_11780	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LU294_11785	COG1984	allophanate hydrolase subunit 2
LU294_11820	COG0768	penicillin binding
LU294_11860	COG4335	DNA alkylation repair
LU294_11870	COG0833	amino acid
LU294_11880	COG0730	response to heat
LU294_11925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LU294_11945	COG0456	acetyltransferase
LU294_11970	COG1136	(ABC) transporter
LU294_11980	COG1725	Transcriptional regulator
LU294_12015	COG1846	Transcriptional regulator
LU294_12020	COG0778	Nitroreductase
LU294_12030	COG0714	Associated with various cellular activities
LU294_12060	COG3403	YqcI/YcgG family
LU294_12065	COG1280	lysine exporter protein (LysE YggA)
LU294_12075	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LU294_12080	COG1846	Transcriptional regulator
LU294_12095	COG1116	anion transmembrane transporter activity
LU294_12100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LU294_12105	COG0753	catalase activity
LU294_12110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LU294_12130	COG0714	Associated with various cellular activities
LU294_12150	COG0346	lactoylglutathione lyase activity
LU294_12175	COG3279	Response regulator of the LytR AlgR family
LU294_12185	COG4377	Putative membrane peptidase family (DUF2324)
LU294_12200	COG3655	Transcriptional regulator
LU294_12210	COG1785	Belongs to the alkaline phosphatase family
LU294_12220	COG3239	Fatty acid desaturase
LU294_12225	COG1690	Belongs to the RtcB family
LU294_12230	COG0833	amino acid
LU294_12235	COG1414	Transcriptional regulator
LU294_12240	COG4187	Peptidase family M20/M25/M40
LU294_12245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LU294_12260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LU294_12275	COG2329	Antibiotic biosynthesis monooxygenase
LU294_12300	COG1070	Carbohydrate kinase
LU294_12305	COG2390	Transcriptional regulator
LU294_12315	COG1172	Belongs to the binding-protein-dependent transport system permease family
LU294_12340	COG1309	transcriptional regulator
LU294_12355	COG3584	3D domain protein
LU294_12355	COG1388	LysM domain
LU294_12390	COG1605	Chorismate mutase
LU294_12390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LU294_12405	COG0287	Prephenate dehydrogenase
LU294_12420	COG1309	transcriptional regulator
LU294_12425	COG2409	Drug exporters of the RND superfamily
LU294_12425	COG1033	growth of symbiont in host cell
LU294_12440	COG0488	(ABC) transporter
LU294_12445	COG1368	sulfuric ester hydrolase activity
LU294_12450	COG0861	Integral membrane protein TerC family
LU294_12470	COG0346	lactoylglutathione lyase activity
LU294_12480	COG4912	Dna alkylation repair
LU294_12500	COG2318	DinB family
LU294_12505	COG0697	spore germination
LU294_12525	COG2746	aminoglycoside 3-N-acetyltransferase activity
LU294_12570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LU294_12575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LU294_12580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LU294_12595	COG0628	permease
LU294_12645	COG1131	(ABC) transporter
LU294_12670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LU294_12675	COG0436	Aminotransferase
LU294_12710	COG2226	methyltransferase
LU294_12725	COG2261	transglycosylase associated protein
LU294_12745	COG0477	Major facilitator Superfamily
LU294_12745	COG2814	Major facilitator Superfamily
LU294_12750	COG4533	DNA binding
LU294_12755	COG0789	Transcriptional regulator
LU294_12760	COG1664	Polymer-forming cytoskeletal
LU294_12770	COG2814	Major facilitator Superfamily
LU294_12805	COG1307	EDD domain protein, DegV family
LU294_12815	COG1164	Oligoendopeptidase f
LU294_12850	COG0745	RESPONSE REGULATOR receiver
LU294_12860	COG2936	dipeptidyl-peptidase activity
LU294_12910	COG4948	Mandelate Racemase Muconate Lactonizing
LU294_12920	COG4166	transmembrane transport
LU294_12925	COG0519	Catalyzes the synthesis of GMP from XMP
LU294_12930	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LU294_12945	COG0586	Pfam SNARE associated Golgi protein
LU294_12985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LU294_12990	COG3938	Belongs to the proline racemase family
LU294_13000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LU294_13005	COG1012	belongs to the aldehyde dehydrogenase family
LU294_13010	COG1115	amino acid carrier protein
LU294_13015	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LU294_13030	COG3397	chitin binding
LU294_13050	COG4637	Psort location Cytoplasmic, score
LU294_13080	COG0514	ATP-dependent DNA helicase (RecQ)
LU294_13085	COG2105	PFAM AIG2 family protein
LU294_13100	COG3973	AAA domain
LU294_13150	COG0658	competence protein
LU294_13150	COG2333	competence protein COMEC
LU294_13160	COG2315	Protein conserved in bacteria
LU294_13170	COG2205	protein histidine kinase activity
LU294_13190	COG1819	glycosyl
LU294_13195	COG3397	chitin binding
LU294_13200	COG2153	protein acetylation
LU294_13230	COG0517	IMP dehydrogenase activity
LU294_13230	COG4175	Glycine betaine
LU294_13235	COG4176	ABC-type proline glycine betaine transport system permease component
LU294_13260	COG0494	nUDIX hydrolase
LU294_13270	COG0456	acetyltransferase
LU294_13270	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LU294_13275	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_13285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LU294_13290	COG0022	dehydrogenase e1 component
LU294_13295	COG0508	dehydrogenase complex catalyzes the overall conversion of
LU294_13300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LU294_13315	COG1349	DNA-binding transcription factor activity
LU294_13335	COG3284	Transcriptional regulator
LU294_13355	COG1309	transcriptional regulator
LU294_13390	COG2959	enzyme of heme biosynthesis
LU294_13405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LU294_13445	COG0201	protein transport
LU294_13450	COG0346	lactoylglutathione lyase activity
LU294_13470	COG3227	Zinc metalloprotease (Elastase)
LU294_13475	COG1523	belongs to the glycosyl hydrolase 13 family
LU294_13495	COG1011	Hydrolase
LU294_13520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LU294_13560	COG0322	excinuclease ABC activity
LU294_13600	COG4667	esterase of the alpha-beta hydrolase superfamily
LU294_13620	COG3878	Protein conserved in bacteria
LU294_13650	COG1051	belongs to the nudix hydrolase family
LU294_13655	COG0592	DNA-directed DNA polymerase activity
LU294_13660	COG2816	NAD+ diphosphatase activity
LU294_13675	COG2223	nitrite transmembrane transporter activity
LU294_13685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LU294_13695	COG0494	nUDIX hydrolase
LU294_13700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LU294_13710	COG0697	spore germination
LU294_13715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LU294_13735	COG0584	glycerophosphoryl diester phosphodiesterase
LU294_13750	COG2814	Major facilitator Superfamily
LU294_13760	COG0456	acetyltransferase
LU294_13765	COG0693	protein deglycase activity
LU294_13815	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_13825	COG0768	penicillin binding
LU294_13830	COG0671	phosphoesterase, PA-phosphatase related
LU294_13835	COG0604	alcohol dehydrogenase
LU294_13840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LU294_13875	COG1794	racemase activity, acting on amino acids and derivatives
LU294_13880	COG1819	glycosyl
LU294_13885	COG0768	penicillin binding
LU294_13890	COG5002	protein histidine kinase activity
LU294_13895	COG0561	phosphatase activity
LU294_13925	COG2124	cytochrome p450
LU294_13975	COG5444	nuclease activity
LU294_14010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LU294_14020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LU294_14025	COG0460	homoserine dehydrogenase
LU294_14045	COG0577	efflux transmembrane transporter activity
LU294_14050	COG1136	(ABC) transporter
LU294_14060	COG0488	(ABC) transporter
LU294_14070	COG2205	protein histidine kinase activity
LU294_14075	COG0745	RESPONSE REGULATOR receiver
LU294_14085	COG3773	Cell wall hydrolase
LU294_14090	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LU294_14100	COG3386	PFAM SMP-30 Gluconolaconase
LU294_14110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LU294_14115	COG2323	membrane
LU294_14135	COG2368	4-hydroxyphenylacetate
LU294_14140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LU294_14155	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LU294_14170	COG2226	methyltransferase
LU294_14190	COG0789	Transcriptional regulator
LU294_14220	COG3227	Zinc metalloprotease (Elastase)
LU294_14245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LU294_14270	COG1686	Belongs to the peptidase S11 family
LU294_14285	COG0572	uridine kinase
LU294_14290	COG1247	-acetyltransferase
LU294_14305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LU294_14310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LU294_14315	COG1024	Enoyl-CoA hydratase
LU294_14320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LU294_14325	COG0511	ligase activity, forming carbon-carbon bonds
LU294_14330	COG0439	Biotin carboxylase
LU294_14335	COG1960	acyl-CoA dehydrogenase activity
LU294_14350	COG1309	transcriptional regulator
LU294_14360	COG1131	(ABC) transporter
LU294_14370	COG1408	metallophosphoesterase
LU294_14375	COG2367	Beta-lactamase
LU294_14390	COG0768	penicillin binding
LU294_14395	COG0768	penicillin binding
LU294_14405	COG1595	DNA-templated transcription, initiation
LU294_14420	COG2195	Cleaves the N-terminal amino acid of tripeptides
LU294_14470	COG3961	Belongs to the TPP enzyme family
LU294_14475	COG2226	methyltransferase
LU294_14485	COG3615	Tellurite resistance protein tehB
LU294_14485	COG0500	methyltransferase
LU294_14490	COG1136	(ABC) transporter
LU294_14490	COG0577	efflux transmembrane transporter activity
LU294_14505	COG1309	transcriptional regulator
LU294_14535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LU294_14555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LU294_14565	COG2971	BadF BadG BcrA BcrD
LU294_14590	COG1649	PFAM Uncharacterised BCR, COG1649
LU294_14615	COG1595	DNA-templated transcription, initiation
LU294_14620	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
LU294_14660	COG1396	sequence-specific DNA binding
LU294_14675	COG1132	(ABC) transporter
LU294_14680	COG1132	(ABC) transporter
LU294_14695	COG2258	MOSC domain
LU294_14700	COG0583	DNA-binding transcription factor activity
LU294_14715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LU294_14720	COG0583	DNA-binding transcription factor activity
LU294_14725	COG2814	Major facilitator Superfamily
LU294_14730	COG1846	Transcriptional regulator
LU294_14740	COG0561	phosphatase activity
LU294_14760	COG1278	Cold shock
LU294_14770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LU294_14780	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LU294_14810	COG1247	-acetyltransferase
LU294_14880	COG2226	methyltransferase
LU294_14890	COG0028	Belongs to the TPP enzyme family
LU294_14905	COG2814	Major facilitator Superfamily
LU294_14910	COG0596	Alpha beta hydrolase
LU294_14920	COG1136	(ABC) transporter
LU294_14925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LU294_14930	COG1187	pseudouridine synthase activity
LU294_14935	COG2329	Antibiotic biosynthesis monooxygenase
LU294_14965	COG1115	amino acid carrier protein
LU294_14975	COG2318	DinB family
LU294_14985	COG0776	regulation of translation
LU294_15000	COG2814	Major facilitator Superfamily
LU294_15005	COG3251	PFAM MbtH domain protein
LU294_15010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LU294_15015	COG3433	isochorismatase activity
LU294_15015	COG1535	isochorismatase
LU294_15020	COG1021	2,3-dihydroxybenzoate-AMP ligase
LU294_15025	COG1169	isochorismate synthase
LU294_15030	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_15035	COG2223	nitrite transmembrane transporter activity
LU294_15065	COG0420	3'-5' exonuclease activity
LU294_15080	COG1024	Enoyl-CoA hydratase
LU294_15085	COG1280	lysine exporter protein (LysE YggA)
LU294_15095	COG2084	Dehydrogenase
LU294_15100	COG1960	acyl-CoA dehydrogenase activity
LU294_15105	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LU294_15110	COG2079	MmgE PrpD family protein
LU294_15115	COG0372	Belongs to the citrate synthase family
LU294_15120	COG4841	protein insertion into membrane
LU294_15125	COG2814	Major facilitator Superfamily
LU294_15135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LU294_15135	COG4499	WXG100 protein secretion system (Wss), protein YukC
LU294_15175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LU294_15200	COG1595	DNA-templated transcription, initiation
LU294_15230	COG5484	DNA packaging
LU294_15230	COG3728	DNA packaging
LU294_15245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LU294_15250	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LU294_15255	COG0671	phosphoesterase, PA-phosphatase related
LU294_15260	COG4326	sporulation control protein
LU294_15265	COG0515	serine threonine protein kinase
LU294_15265	COG4991	sh3 domain protein
LU294_15265	COG3064	Membrane
LU294_15300	COG1509	lysine 2,3-aminomutase activity
LU294_15305	COG3829	transcription factor binding
LU294_15310	COG0456	acetyltransferase
LU294_15315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LU294_15320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LU294_15325	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LU294_15330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LU294_15345	COG5506	Protein of unknown function (DUF1694)
LU294_15350	COG1012	belongs to the aldehyde dehydrogenase family
LU294_15355	COG1253	flavin adenine dinucleotide binding
LU294_15390	COG1174	glycine betaine transport
LU294_15395	COG0517	IMP dehydrogenase activity
LU294_15395	COG1125	glycine betaine transport
LU294_15460	COG1064	alcohol dehydrogenase
LU294_15470	COG2197	response regulator
LU294_15475	COG4585	Histidine kinase
LU294_15475	COG2203	Gaf domain
LU294_15480	COG0668	transmembrane transport
LU294_15485	COG0071	Belongs to the small heat shock protein (HSP20) family
LU294_15490	COG1051	belongs to the nudix hydrolase family
LU294_15495	COG1335	isochorismatase
LU294_15510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LU294_15515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LU294_15535	COG0367	asparagine synthase
LU294_15540	COG0071	Belongs to the small heat shock protein (HSP20) family
LU294_15545	COG1999	signal sequence binding
LU294_15550	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LU294_15555	COG1307	EDD domain protein, DegV family
LU294_15565	COG0805	protein transport
LU294_15575	COG1272	protein, Hemolysin III
LU294_15580	COG0204	Acyl-transferase
LU294_15590	COG0768	penicillin binding
LU294_15605	COG3250	beta-galactosidase activity
LU294_15610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LU294_15625	COG0546	phosphoglycolate phosphatase activity
LU294_15635	COG4473	ABC transporter
LU294_15640	COG1131	(ABC) transporter
LU294_15650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LU294_15655	COG0456	acetyltransferase
LU294_15665	COG1794	racemase activity, acting on amino acids and derivatives
LU294_15670	COG1454	alcohol dehydrogenase
LU294_15675	COG2610	gluconate transmembrane transporter activity
LU294_15700	COG0733	neurotransmitter:sodium symporter activity
LU294_15740	COG5444	nuclease activity
LU294_15765	COG1674	ftsk spoiiie
LU294_15785	COG0017	Asparaginyl-tRNA synthetase
LU294_15790	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LU294_15830	COG0018	arginyl-trna synthetase
LU294_15835	COG2136	Putative SAM-dependent methyltransferase
LU294_15835	COG2521	methyltransferase
LU294_15850	COG1413	lyase activity
LU294_15865	COG0629	single-stranded DNA binding
LU294_15880	COG0488	(ABC) transporter
LU294_15885	COG1418	mRNA catabolic process
LU294_15905	COG2359	stage V sporulation protein S
LU294_15930	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
LU294_15935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LU294_15940	COG2146	nitrite reductase [NAD(P)H] activity
LU294_15945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LU294_15945	COG1587	Uroporphyrinogen-III synthase
LU294_15955	COG1648	precorrin-2 dehydrogenase activity
LU294_15975	COG2223	nitrite transmembrane transporter activity
LU294_15985	COG0314	molybdopterin synthase activity
LU294_15990	COG0303	'Molybdopterin
LU294_15995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LU294_16000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LU294_16005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LU294_16010	COG2181	nitrate reductase activity
LU294_16015	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LU294_16020	COG1140	nitrate reductase beta subunit
LU294_16025	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LU294_16040	COG0714	Associated with various cellular activities
LU294_16045	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LU294_16050	COG1305	Transglutaminase-like
LU294_16055	COG0386	Belongs to the glutathione peroxidase family
LU294_16065	COG0426	domain, Protein
LU294_16065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LU294_16080	COG1595	DNA-templated transcription, initiation
LU294_16085	COG0604	alcohol dehydrogenase
LU294_16095	COG0346	lactoylglutathione lyase activity
LU294_16100	COG1082	Xylose isomerase domain protein TIM barrel
LU294_16120	COG2226	methyltransferase
LU294_16145	COG3874	Sporulation protein YtfJ
LU294_16170	COG0456	acetyltransferase
LU294_16200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LU294_16205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LU294_16210	COG1819	glycosyl
LU294_16225	COG4106	trans-aconitate 2-methyltransferase activity
LU294_16230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LU294_16240	COG0561	phosphatase activity
LU294_16250	COG1942	4-Oxalocrotonate Tautomerase
LU294_16270	COG3971	2-oxopent-4-enoate hydratase activity
LU294_16280	COG0251	oxidation-reduction process
LU294_16295	COG0196	riboflavin kinase activity
LU294_16305	COG2368	4-hydroxyphenylacetate
LU294_16320	COG2211	Major facilitator Superfamily
LU294_16325	COG0154	amidase activity
LU294_16335	COG1876	peptidase activity
LU294_16345	COG0860	N-Acetylmuramoyl-L-alanine amidase
LU294_16365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LU294_16370	COG1114	Component of the transport system for branched-chain amino acids
LU294_16385	COG1253	flavin adenine dinucleotide binding
LU294_16390	COG2839	Protein conserved in bacteria
LU294_16395	COG0702	epimerase
LU294_16410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LU294_16420	COG1607	acyl-coa hydrolase
LU294_16425	COG3689	TIGRFAM TIGR03943 family protein
LU294_16430	COG0701	Predicted permease
LU294_16440	COG2244	polysaccharide biosynthetic process
LU294_16445	COG0586	Pfam SNARE associated Golgi protein
LU294_16450	COG1051	belongs to the nudix hydrolase family
LU294_16455	COG5337	Spore coat protein CotH
LU294_16465	COG0406	alpha-ribazole phosphatase activity
LU294_16480	COG4166	transmembrane transport
LU294_16490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LU294_16500	COG0702	epimerase
LU294_16510	COG3443	Belongs to the bacterial solute-binding protein 9 family
LU294_16510	COG0803	Belongs to the bacterial solute-binding protein 9 family
LU294_16530	COG0456	acetyltransferase
LU294_16535	COG0523	cobalamin synthesis protein
LU294_16540	COG4989	oxidoreductase activity
LU294_16545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LU294_16550	COG1231	oxidoreductase activity
LU294_16560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LU294_16575	COG0783	Belongs to the Dps family
LU294_16580	COG3949	Membrane
LU294_16595	COG0840	transmembrane signaling receptor activity
LU294_16620	COG2814	Major facilitator Superfamily
LU294_16630	COG0640	Transcriptional regulator
LU294_16635	COG1404	Belongs to the peptidase S8 family
LU294_16640	COG2002	toxin-antitoxin pair type II binding
LU294_16645	COG0577	efflux transmembrane transporter activity
LU294_16680	COG1752	Esterase of the alpha-beta hydrolase superfamily
LU294_16690	COG1279	arginine transmembrane transporter activity
LU294_16695	COG2814	Major facilitator Superfamily
LU294_16705	COG1247	-acetyltransferase
LU294_16710	COG1285	pathogenesis
LU294_16730	COG1316	TRANSCRIPTIONal
LU294_16755	COG0460	homoserine dehydrogenase
LU294_16785	COG0300	oxidoreductase activity
LU294_16795	COG5002	protein histidine kinase activity
LU294_16800	COG0745	RESPONSE REGULATOR receiver
LU294_16805	COG1132	(ABC) transporter
LU294_16815	COG1388	LysM domain
LU294_16815	COG0791	NLP P60 protein
LU294_16830	COG1686	Belongs to the peptidase S11 family
LU294_16870	COG1216	Glycosyl transferase, family 2
LU294_16880	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LU294_16885	COG4988	ABC transporter
LU294_16890	COG1294	oxidase, subunit
LU294_16895	COG1271	oxidase subunit
LU294_16915	COG1942	4-Oxalocrotonate Tautomerase
LU294_16945	COG0411	ABC transporter
LU294_16955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LU294_16960	COG2030	dehydratase
LU294_16965	COG0318	PFAM AMP-dependent synthetase and ligase
LU294_16975	COG0523	cobalamin synthesis protein
LU294_16980	COG1231	oxidoreductase activity
LU294_16990	COG0628	permease
LU294_17000	COG0778	Nitroreductase
LU294_17005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LU294_17010	COG1959	2 iron, 2 sulfur cluster binding
LU294_17015	COG0583	DNA-binding transcription factor activity
LU294_17020	COG0697	spore germination
LU294_17030	COG4549	nuclear export factor GLE1
LU294_17035	COG2372	response to copper ion
LU294_17035	COG1276	copper resistance
LU294_17045	COG1114	Component of the transport system for branched-chain amino acids
LU294_17070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LU294_17085	COG0006	proline dipeptidase activity
LU294_17095	COG4846	Membrane protein involved in cytochrome C biogenesis
LU294_17105	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LU294_17110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LU294_17120	COG2390	Transcriptional regulator
LU294_17145	COG0531	amino acid
LU294_17150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LU294_17165	COG1914	H( )-stimulated, divalent metal cation uptake system
LU294_17185	COG0745	RESPONSE REGULATOR receiver
LU294_17190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LU294_17195	COG0535	radical SAM domain protein
LU294_17230	COG4166	transmembrane transport
LU294_17235	COG1073	alpha beta
LU294_17255	COG0427	acetyl-CoA hydrolase
LU294_17260	COG3279	Response regulator of the LytR AlgR family
LU294_17270	COG3384	dioxygenase
LU294_17275	COG2814	Major facilitator Superfamily
LU294_17300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LU294_17310	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LU294_17315	COG0440	acetolactate synthase activity
LU294_17320	COG0028	Belongs to the TPP enzyme family
LU294_17325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LU294_17330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LU294_17345	COG2323	membrane
LU294_17350	COG5566	PFAM Mor transcription activator
LU294_17360	COG0733	neurotransmitter:sodium symporter activity
LU294_17365	COG2244	polysaccharide biosynthetic process
LU294_17380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LU294_17385	COG2223	nitrite transmembrane transporter activity
LU294_17390	COG4166	transmembrane transport
LU294_17395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LU294_17405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LU294_17410	COG0477	Major facilitator Superfamily
LU294_17420	COG1695	Transcriptional regulator
LU294_17435	COG1105	Belongs to the carbohydrate kinase PfkB family
LU294_17450	COG2222	sugar isomerase
LU294_17455	COG2188	Transcriptional regulator
LU294_17465	COG0395	ABC-type sugar transport system, permease component
LU294_17470	COG1175	transmembrane transport
LU294_17480	COG2508	Transcriptional regulator
LU294_17485	COG3842	ATPase activity
LU294_17500	COG2814	Major facilitator Superfamily
LU294_17510	COG0860	N-Acetylmuramoyl-L-alanine amidase
LU294_17515	COG1051	belongs to the nudix hydrolase family
LU294_17545	COG3620	sequence-specific DNA binding
LU294_17565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LU294_17570	COG0784	Response regulator, receiver
LU294_17575	COG4191	Histidine kinase
LU294_17580	COG0281	malic enzyme
LU294_17585	COG1027	Aspartate ammonia-lyase
LU294_17595	COG0528	UMP kinase activity
LU294_17600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LU294_17615	COG1131	(ABC) transporter
LU294_17650	COG2733	membrane
LU294_17690	COG3340	Belongs to the peptidase S51 family
LU294_17695	COG0534	Mate efflux family protein
LU294_17715	COG0114	fumarate hydratase activity
LU294_17720	COG1757	Na H antiporter
LU294_17725	COG0438	transferase activity, transferring glycosyl groups
LU294_17725	COG1216	Glycosyl transferase, family 2
LU294_17730	COG0697	spore germination
LU294_17735	COG1802	Transcriptional regulator
LU294_17765	COG0367	asparagine synthase
LU294_17775	COG1846	Transcriptional regulator
LU294_17795	COG0406	alpha-ribazole phosphatase activity
LU294_17805	COG1686	Belongs to the peptidase S11 family
LU294_17845	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_17865	COG1234	tRNA 3'-trailer cleavage
LU294_17875	COG0725	ABC transporter, periplasmic molybdate-binding protein
LU294_17880	COG3842	ATPase activity
LU294_17885	COG0583	DNA-binding transcription factor activity
LU294_17910	COG3764	Sortase (surface protein transpeptidase)
LU294_17915	COG3764	Sortase (surface protein transpeptidase)
LU294_17930	COG2329	Antibiotic biosynthesis monooxygenase
LU294_17950	COG1309	transcriptional regulator
LU294_17975	COG4786	Flagellar basal body rod
LU294_17980	COG1419	protein localization to endoplasmic reticulum
LU294_17985	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LU294_17990	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LU294_18000	COG1987	bacterial-type flagellum assembly
LU294_18005	COG1338	Plays a role in the flagellum-specific transport system
LU294_18015	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LU294_18015	COG1776	CheC inhibitor of MCP methylation
LU294_18020	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LU294_18030	COG0741	lytic transglycosylase activity
LU294_18040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LU294_18050	COG0784	Response regulator, receiver
LU294_18050	COG0835	chemotaxis
LU294_18085	COG1157	protein secretion by the type III secretion system
LU294_18095	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LU294_18100	COG1766	The M ring may be actively involved in energy transduction
LU294_18110	COG1558	bacterial-type flagellum-dependent cell motility
LU294_18115	COG1815	bacterial-type flagellum-dependent cell motility
LU294_18135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LU294_18140	COG1256	bacterial-type flagellum assembly
LU294_18160	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LU294_18175	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LU294_18175	COG1776	CheC inhibitor of MCP methylation
LU294_18180	COG0643	Histidine kinase
LU294_18180	COG2198	Histidine kinase
LU294_18185	COG2201	protein-glutamate methylesterase activity
LU294_18190	COG1360	Flagellar Motor Protein
LU294_18195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LU294_18205	COG1923	regulation of RNA biosynthetic process
LU294_18225	COG2814	Major facilitator Superfamily
LU294_18235	COG2814	Major facilitator Superfamily
LU294_18265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LU294_18270	COG2323	membrane
LU294_18280	COG4978	Transcriptional regulator
LU294_18280	COG0789	Transcriptional regulator
LU294_18285	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LU294_18290	COG0475	glutathione-regulated potassium exporter activity
LU294_18300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LU294_18305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LU294_18310	COG3162	membrane
LU294_18325	COG1280	lysine exporter protein (LysE YggA)
LU294_18330	COG3403	YqcI/YcgG family
LU294_18365	COG0328	RNA-DNA hybrid ribonuclease activity
LU294_18385	COG0454	-acetyltransferase
LU294_18400	COG0438	transferase activity, transferring glycosyl groups
LU294_18405	COG1215	transferase activity, transferring glycosyl groups
LU294_18420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LU294_18445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LU294_18460	COG0754	glutathionylspermidine amidase activity
LU294_18495	COG0456	acetyltransferase
LU294_18505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LU294_18510	COG2311	Membrane
LU294_18515	COG2233	PERMEase
LU294_18525	COG0024	Methionine aminopeptidase
LU294_18535	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LU294_18540	COG1199	ATP-dependent helicase activity
LU294_18550	COG0116	Belongs to the methyltransferase superfamily
LU294_18610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LU294_18610	COG4499	WXG100 protein secretion system (Wss), protein YukC
LU294_18620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LU294_18625	COG3935	DnaD domain protein
LU294_18645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LU294_18645	COG1199	ATP-dependent helicase activity
LU294_18680	COG0438	transferase activity, transferring glycosyl groups
LU294_18685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LU294_18700	COG1694	Mazg nucleotide pyrophosphohydrolase
LU294_18705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LU294_18715	COG2738	Putative neutral zinc metallopeptidase
LU294_18730	COG4347	Protein of unknown function (DUF1405)
LU294_18735	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LU294_18735	COG2010	Cytochrome c
LU294_18740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LU294_18760	COG0457	Tetratricopeptide repeat
LU294_18770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LU294_18790	COG0142	geranyltranstransferase activity
LU294_18800	COG0142	geranyltranstransferase activity
LU294_18815	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LU294_18885	COG0252	asparaginase activity
LU294_18890	COG0492	ferredoxin-NADP+ reductase activity
LU294_18910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LU294_18915	COG4862	establishment of competence for transformation
LU294_18925	COG1408	metallophosphoesterase
LU294_18935	COG1266	CAAX protease self-immunity
LU294_18940	COG0514	ATP-dependent DNA helicase (RecQ)
LU294_18950	COG1141	Ferredoxin
LU294_18955	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LU294_18965	COG4942	peptidase
LU294_18970	COG2096	Adenosyltransferase
LU294_18975	COG5002	protein histidine kinase activity
LU294_18980	COG0745	RESPONSE REGULATOR receiver
LU294_18985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LU294_18990	COG1333	cytochrome c biogenesis protein
LU294_19000	COG1187	pseudouridine synthase activity
LU294_19005	COG0700	Nucleoside recognition
LU294_19010	COG2715	membrane protein required for spore maturation
LU294_19015	COG1686	Belongs to the peptidase S11 family
LU294_19020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LU294_19035	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LU294_19035	COG0392	lysyltransferase activity
LU294_19050	COG5002	protein histidine kinase activity
LU294_19055	COG0582	viral genome integration into host DNA
LU294_19065	COG1801	Protein of unknown function DUF72
LU294_19070	COG3852	Histidine kinase
LU294_19085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LU294_19090	COG1392	Phosphate transport regulator
LU294_19095	COG0306	phosphate transporter
LU294_19100	COG0730	response to heat
LU294_19140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LU294_19150	COG1114	Component of the transport system for branched-chain amino acids
LU294_19160	COG2197	response regulator
LU294_19165	COG4585	Histidine kinase
LU294_19170	COG4758	membrane
LU294_19185	COG1757	Na H antiporter
LU294_19210	COG0733	neurotransmitter:sodium symporter activity
LU294_19215	COG1648	precorrin-2 dehydrogenase activity
LU294_19235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LU294_19240	COG0529	Catalyzes the synthesis of activated sulfate
LU294_19260	COG0019	diaminopimelate decarboxylase activity
LU294_19270	COG1368	sulfuric ester hydrolase activity
LU294_19275	COG1183	phosphatidylcholine synthase activity
LU294_19290	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LU294_19365	COG0440	acetolactate synthase activity
LU294_19370	COG0028	Belongs to the TPP enzyme family
LU294_19375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LU294_19395	COG3874	Sporulation protein YtfJ
LU294_19400	COG4709	membrane
LU294_19405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LU294_19410	COG1301	dicarboxylic acid transport
LU294_19420	COG1846	Transcriptional regulator
LU294_19460	COG3173	Aminoglycoside phosphotransferase
LU294_19475	COG0716	FMN binding
LU294_19500	COG1696	Membrane protein involved in D-alanine export
LU294_19510	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LU294_19515	COG2070	2-Nitropropane dioxygenase
LU294_19520	COG1619	proteins homologs of microcin C7 resistance protein MccF
LU294_19530	COG1335	isochorismatase
LU294_19540	COG1522	sequence-specific DNA binding
LU294_19550	COG1266	CAAX protease self-immunity
LU294_19555	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LU294_19560	COG1131	(ABC) transporter
LU294_19570	COG1131	(ABC) transporter
LU294_19575	COG1725	Transcriptional regulator
LU294_19580	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LU294_19595	COG1780	Probably involved in ribonucleotide reductase function
LU294_19625	COG4873	Protein conserved in bacteria
LU294_19640	COG0720	synthase
LU294_19650	COG5002	protein histidine kinase activity
LU294_19660	COG2318	DinB family
LU294_19670	COG1846	Transcriptional regulator
LU294_19675	COG3852	Histidine kinase
LU294_19685	COG2861	carbohydrate metabolic process
LU294_19695	COG0235	Class ii aldolase
LU294_19705	COG1349	DNA-binding transcription factor activity
LU294_19730	COG3842	ATPase activity
LU294_19735	COG1840	ABC-type Fe3 transport system, periplasmic component
LU294_19750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LU294_19760	COG3243	poly(R)-hydroxyalkanoic acid synthase
LU294_19765	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_19785	COG2030	dehydratase
LU294_19795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LU294_19800	COG0861	Integral membrane protein TerC family
LU294_19805	COG2116	formate transmembrane transporter activity
LU294_19815	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LU294_19835	COG2186	Transcriptional regulator
LU294_19840	COG5002	protein histidine kinase activity
LU294_19845	COG0745	RESPONSE REGULATOR receiver
LU294_19855	COG3835	regulator
LU294_19860	COG0277	FAD linked oxidase domain protein
LU294_19865	COG0247	lactate metabolic process
LU294_19870	COG2340	Cysteine-rich secretory protein family
LU294_19880	COG0564	pseudouridine synthase activity
LU294_19890	COG2409	Drug exporters of the RND superfamily
LU294_19900	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LU294_19905	COG1177	transmembrane transport
LU294_19910	COG1176	ABC-type spermidine putrescine transport system, permease component I
LU294_19920	COG1012	belongs to the aldehyde dehydrogenase family
LU294_19935	COG1396	sequence-specific DNA binding
LU294_19955	COG0681	Belongs to the peptidase S26 family
LU294_19960	COG1686	Belongs to the peptidase S11 family
LU294_19970	COG2226	methyltransferase
LU294_20015	COG1476	TRANSCRIPTIONal
LU294_20025	COG0508	dehydrogenase complex catalyzes the overall conversion of
LU294_20085	COG5634	Uncharacterized conserved protein (DUF2278)
LU294_20090	COG1620	l-lactate permease
LU294_20125	COG0512	Glutamine amidotransferase of anthranilate synthase
LU294_20125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LU294_20135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LU294_20140	COG5492	domain, Protein
LU294_20155	COG2382	esterase
LU294_20165	COG2153	protein acetylation
LU294_20210	COG1091	dTDP-4-dehydrorhamnose reductase activity
LU294_20225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LU294_20245	COG0457	Tetratricopeptide repeat
LU294_20245	COG0463	Glycosyl transferase, family 2
LU294_20265	COG1216	Glycosyl transferase, family 2
LU294_20270	COG0772	Belongs to the SEDS family
LU294_20285	COG0564	pseudouridine synthase activity
LU294_20295	COG2357	RelA SpoT domain protein
LU294_20305	COG4116	CYTH
LU294_20310	COG2346	COG2346, Truncated hemoglobins
LU294_20325	COG1164	Oligoendopeptidase f
LU294_20335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LU294_20340	COG4862	establishment of competence for transformation
LU294_20345	COG0861	Integral membrane protein TerC family
LU294_20360	COG4166	transmembrane transport
LU294_20365	COG0534	Mate efflux family protein
LU294_20370	COG4608	Belongs to the ABC transporter superfamily
LU294_20375	COG0444	Belongs to the ABC transporter superfamily
LU294_20380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LU294_20385	COG0601	transmembrane transport
LU294_20390	COG4166	transmembrane transport
LU294_20400	COG0180	Tryptophanyl-tRNA synthetase
LU294_20415	COG5504	Zn-dependent protease
LU294_20420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LU294_20425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LU294_20440	COG2267	carboxylic ester hydrolase activity
LU294_20460	COG0561	phosphatase activity
LU294_20475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LU294_20485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LU294_20490	COG2996	Protein conserved in bacteria
LU294_20510	COG0004	ammonium transporteR
LU294_20515	COG0753	catalase activity
LU294_20520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LU294_20525	COG0367	asparagine synthase
LU294_20550	COG0179	Fumarylacetoacetate (FAA) hydrolase
LU294_20610	COG0398	Pfam SNARE associated Golgi protein
LU294_20625	COG4585	Histidine kinase
LU294_20630	COG4903	ComK protein
LU294_20655	COG2224	Isocitrate lyase
LU294_20660	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LU294_20680	COG0697	spore germination
LU294_20685	COG0501	Belongs to the peptidase M48B family
LU294_20710	COG0745	RESPONSE REGULATOR receiver
LU294_20715	COG2205	protein histidine kinase activity
LU294_20730	COG2207	Transcriptional regulator
LU294_20730	COG3708	Transcriptional regulator
LU294_20735	COG1595	DNA-templated transcription, initiation
LU294_20745	COG0477	Major facilitator Superfamily
LU294_20755	COG1078	dGTPase activity
LU294_20760	COG1408	metallophosphoesterase
LU294_20805	COG0318	PFAM AMP-dependent synthetase and ligase
LU294_20815	COG0095	Lipoate-protein ligase
LU294_20820	COG1234	tRNA 3'-trailer cleavage
LU294_20830	COG1609	Transcriptional regulator
LU294_20835	COG2378	regulation of single-species biofilm formation
LU294_20845	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LU294_20865	COG1511	domain protein
LU294_20870	COG1309	transcriptional regulator
LU294_20900	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LU294_20915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LU294_20920	COG2329	Antibiotic biosynthesis monooxygenase
LU294_20930	COG3428	Bacterial PH domain
LU294_20935	COG3402	PFAM membrane-flanked domain
LU294_20965	COG3428	Bacterial PH domain
LU294_20970	COG3402	PFAM membrane-flanked domain
LU294_20980	COG1309	transcriptional regulator
LU294_21050	COG4473	ABC transporter
LU294_21055	COG1131	(ABC) transporter
LU294_21060	COG0537	adenosine 5'-monophosphoramidase activity
LU294_21065	COG4980	gas vesicle protein
LU294_21085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LU294_21090	COG3973	AAA domain
LU294_21100	COG0477	Major facilitator Superfamily
LU294_21105	COG0477	Major facilitator Superfamily
LU294_21120	COG0772	Belongs to the SEDS family
LU294_21140	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LU294_21150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LU294_21155	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LU294_21170	COG2267	carboxylic ester hydrolase activity
LU294_21180	COG0457	Tetratricopeptide repeat
LU294_21185	COG0346	lactoylglutathione lyase activity
LU294_21190	COG0346	lactoylglutathione lyase activity
LU294_21210	COG4717	serine-type aminopeptidase activity
LU294_21215	COG0420	3'-5' exonuclease activity
LU294_21280	COG0784	Response regulator, receiver
LU294_21280	COG2198	Histidine kinase
LU294_21280	COG2205	protein histidine kinase activity
LU294_21285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LU294_21290	COG2208	phosphoserine phosphatase activity
LU294_21300	COG1191	sigma factor activity
LU294_21325	COG3237	CsbD-like
LU294_21405	COG2376	Dihydroxyacetone kinase
LU294_21415	COG2376	Dihydroxyacetone kinase
LU294_21430	COG1183	phosphatidylcholine synthase activity
LU294_21440	COG2723	6-phospho-beta-galactosidase activity
LU294_21445	COG1263	PTS System
LU294_21445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LU294_21445	COG2190	(PTS) system
LU294_21450	COG3711	transcriptional antiterminator
LU294_21500	COG0477	Major facilitator Superfamily
LU294_21525	COG0305	Participates in initiation and elongation during chromosome replication
LU294_21540	COG4978	Transcriptional regulator
LU294_21540	COG0789	Transcriptional regulator
LU294_21555	COG0582	viral genome integration into host DNA
LU294_21585	COG0732	type I restriction modification DNA specificity domain
LU294_21640	COG3181	Tripartite tricarboxylate transporter family receptor
LU294_21645	COG4565	transcriptional regulatory protein
LU294_21650	COG3290	protein histidine kinase activity
LU294_21655	COG0477	Major facilitator Superfamily
LU294_21690	COG5002	protein histidine kinase activity
LU294_21695	COG0745	RESPONSE REGULATOR receiver
LU294_21705	COG4608	Belongs to the ABC transporter superfamily
LU294_21710	COG0444	Belongs to the ABC transporter superfamily
LU294_21715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LU294_21720	COG0601	transmembrane transport
LU294_21760	COG1363	Peptidase, m42
LU294_21780	COG1024	Enoyl-CoA hydratase
LU294_21795	COG1696	Membrane protein involved in D-alanine export
LU294_21810	COG4196	transglutaminase domain protein
LU294_21815	COG0860	N-Acetylmuramoyl-L-alanine amidase
LU294_21825	COG2244	polysaccharide biosynthetic process
LU294_21830	COG0653	protein targeting
LU294_21845	COG0659	secondary active sulfate transmembrane transporter activity
LU294_21865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LU294_21870	COG5632	N-Acetylmuramoyl-L-alanine amidase
LU294_21870	COG3409	Peptidoglycan-binding domain 1 protein
LU294_21880	COG0561	phosphatase activity
LU294_21890	COG3527	Alpha-acetolactate decarboxylase
LU294_21895	COG0028	Belongs to the TPP enzyme family
LU294_21940	COG4585	Histidine kinase
LU294_21965	COG0189	ligase activity
LU294_21980	COG1126	abc transporter atp-binding protein
LU294_21985	COG0765	amino acid transport
LU294_21990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LU294_21995	COG1132	(ABC) transporter
LU294_22000	COG1132	(ABC) transporter
LU294_22005	COG1012	belongs to the aldehyde dehydrogenase family
LU294_22015	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LU294_22020	COG0531	amino acid
LU294_22030	COG0753	catalase activity
LU294_22035	COG0693	protein deglycase activity
LU294_22045	COG2211	Major facilitator Superfamily
LU294_22050	COG4533	DNA binding
LU294_22055	COG2249	NAD(P)H dehydrogenase (quinone) activity
LU294_22065	COG1733	regulation of RNA biosynthetic process
LU294_22070	COG1063	alcohol dehydrogenase
LU294_22080	COG2124	cytochrome p450
LU294_22095	COG0657	acetylesterase activity
LU294_22100	COG0657	acetylesterase activity
LU294_22105	COG0477	Major facilitator Superfamily
LU294_22110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LU294_22115	COG1846	Transcriptional regulator
LU294_22125	COG2814	Major facilitator Superfamily
LU294_22130	COG1309	transcriptional regulator
LU294_22135	COG2076	Multidrug Resistance protein
LU294_22150	COG1522	sequence-specific DNA binding
LU294_22170	COG2259	Doxx family
LU294_22180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LU294_22180	COG1263	PTS System
LU294_22190	COG1737	Transcriptional regulator
LU294_22200	COG0475	glutathione-regulated potassium exporter activity
LU294_22205	COG0531	amino acid
LU294_22240	COG0586	Pfam SNARE associated Golgi protein
LU294_22275	COG3546	catalase activity
LU294_22280	COG1114	Component of the transport system for branched-chain amino acids
LU294_22295	COG5522	Integral membrane protein (intg_mem_TP0381)
LU294_22305	COG1136	(ABC) transporter
LU294_22310	COG0577	efflux transmembrane transporter activity
LU294_22315	COG3584	3D domain protein
LU294_22315	COG1388	LysM domain
LU294_22340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LU294_22345	COG1447	Phosphotransferase system cellobiose-specific component IIA
LU294_22350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LU294_22350	COG3711	transcriptional antiterminator
LU294_22360	COG2814	Major facilitator Superfamily
LU294_22365	COG1283	sodium-dependent phosphate transmembrane transporter activity
LU294_22370	COG0604	alcohol dehydrogenase
LU294_22375	COG1316	TRANSCRIPTIONal
LU294_22385	COG0730	response to heat
LU294_22390	COG2210	Belongs to the sulfur carrier protein TusA family
LU294_22400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LU294_22400	COG0425	Belongs to the sulfur carrier protein TusA family
LU294_22405	COG0425	Belongs to the sulfur carrier protein TusA family
LU294_22410	COG0425	Belongs to the sulfur carrier protein TusA family
LU294_22415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LU294_22415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LU294_22420	COG0425	Belongs to the sulfur carrier protein TusA family
LU294_22420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LU294_22425	COG1937	Protein conserved in bacteria
LU294_22430	COG0446	pyridine nucleotide-disulphide oxidoreductase
LU294_22435	COG2719	SpoVR family
LU294_22445	COG0778	Nitroreductase
LU294_22505	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_22510	COG2252	PERMEase
LU294_22525	COG1846	Transcriptional regulator
LU294_22530	COG2814	Major facilitator Superfamily
LU294_22535	COG2205	protein histidine kinase activity
LU294_22575	COG0351	phosphomethylpyrimidine kinase
LU294_22580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LU294_22590	COG2104	thiamine diphosphate biosynthetic process
LU294_22595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LU294_22600	COG0352	thiamine-phosphate diphosphorylase activity
LU294_22605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LU294_22610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LU294_22615	COG1116	anion transmembrane transporter activity
LU294_22620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LU294_22640	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LU294_22760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LU294_22770	COG0581	inorganic phosphate transmembrane transporter activity
LU294_22775	COG0573	inorganic phosphate transmembrane transporter activity
LU294_22780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LU294_22785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LU294_22785	COG1918	ferrous iron import across plasma membrane
LU294_22790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LU294_22795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LU294_22810	COG0531	amino acid
LU294_22815	COG0697	spore germination
LU294_22820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LU294_22835	COG4990	cell redox homeostasis
LU294_22840	COG0833	amino acid
LU294_22845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LU294_22850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LU294_22865	COG0569	domain protein
LU294_22865	COG0475	glutathione-regulated potassium exporter activity
LU294_22875	COG2153	protein acetylation
LU294_22890	COG2252	PERMEase
LU294_22895	COG1113	amino acid transport
LU294_22910	COG1114	Component of the transport system for branched-chain amino acids
LU294_22915	COG3104	oligopeptide transport
LU294_22935	COG1476	TRANSCRIPTIONal
LU294_22940	COG3583	domain protein
LU294_22940	COG3584	3D domain protein
LU294_22945	COG0840	transmembrane signaling receptor activity
LU294_22975	COG3568	Endonuclease Exonuclease Phosphatase
LU294_22995	COG1063	alcohol dehydrogenase
LU294_23020	COG1879	ABC-type sugar transport system periplasmic component
LU294_23025	COG1172	Belongs to the binding-protein-dependent transport system permease family
LU294_23040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LU294_23045	COG1609	Transcriptional regulator
LU294_23050	COG0477	Major facilitator Superfamily
LU294_23055	COG1846	Transcriptional regulator
LU294_23060	COG2271	Major facilitator Superfamily
LU294_23070	COG4608	Belongs to the ABC transporter superfamily
LU294_23075	COG0601	transmembrane transport
LU294_23085	COG0747	negative chemotaxis
LU294_23100	COG0659	secondary active sulfate transmembrane transporter activity
LU294_23115	COG5002	protein histidine kinase activity
LU294_23120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LU294_23125	COG2378	regulation of single-species biofilm formation
LU294_23135	COG1595	DNA-templated transcription, initiation
LU294_23150	COG0833	amino acid
LU294_23155	COG0765	amino acid transport
LU294_23160	COG0765	amino acid transport
LU294_23165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LU294_23170	COG1126	abc transporter atp-binding protein
LU294_23175	COG1115	amino acid carrier protein
LU294_23180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LU294_23195	COG1404	Belongs to the peptidase S8 family
LU294_23200	COG2197	response regulator
LU294_23205	COG4585	Histidine kinase
LU294_23210	COG0697	spore germination
LU294_23225	COG0366	Alpha amylase catalytic
LU294_23230	COG1263	PTS System
LU294_23230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LU294_23235	COG2188	Transcriptional regulator
LU294_23240	COG0531	amino acid
LU294_23260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LU294_23265	COG0714	Associated with various cellular activities
LU294_23270	COG4548	von Willebrand factor, type A
LU294_23280	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LU294_23285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LU294_23290	COG0156	8-amino-7-oxononanoate synthase activity
LU294_23295	COG2226	methyltransferase
LU294_23305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LU294_23310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LU294_23315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LU294_23320	COG3104	oligopeptide transport
LU294_23335	COG1620	l-lactate permease
LU294_23340	COG1027	Aspartate ammonia-lyase
LU294_23345	COG1253	flavin adenine dinucleotide binding
LU294_23350	COG0346	lactoylglutathione lyase activity
LU294_23355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LU294_23360	COG1316	TRANSCRIPTIONal
LU294_23365	COG2720	vancomycin resistance protein
LU294_23385	COG3227	Zinc metalloprotease (Elastase)
LU294_23400	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LU294_23410	COG2217	Heavy metal translocating P-type atpase
LU294_23415	COG0640	Transcriptional regulator
LU294_23420	COG0531	amino acid
LU294_23435	COG2427	Protein of unknown function (DUF1641)
LU294_23440	COG3383	formate dehydrogenase (NAD+) activity
LU294_23445	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LU294_23450	COG0454	-acetyltransferase
LU294_23450	COG0456	acetyltransferase
LU294_23455	COG0745	RESPONSE REGULATOR receiver
LU294_23460	COG5002	protein histidine kinase activity
LU294_23470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LU294_23475	COG0697	spore germination
LU294_23485	COG4990	cell redox homeostasis
LU294_23495	COG5002	protein histidine kinase activity
LU294_23500	COG0745	RESPONSE REGULATOR receiver
LU294_23505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LU294_23515	COG0395	ABC-type sugar transport system, permease component
LU294_23520	COG1175	transmembrane transport
LU294_23525	COG3842	ATPase activity
LU294_23530	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LU294_23555	COG2851	Citrate transporter
LU294_23560	COG4565	transcriptional regulatory protein
LU294_23565	COG3290	protein histidine kinase activity
LU294_23575	COG2268	Band 7 protein
LU294_23580	COG1585	Membrane protein implicated in regulation of membrane protease activity
LU294_23590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LU294_23610	COG2766	serine protein kinase
LU294_23620	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LU294_23630	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LU294_23640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LU294_23645	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LU294_23740	COG4974	Belongs to the 'phage' integrase family
LU294_23840	COG0735	belongs to the Fur family
LU294_23845	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LU294_23865	COG4555	ABC transporter
LU294_23875	COG0067	glutamate synthase
LU294_23875	COG0070	glutamate synthase
LU294_23875	COG0069	glutamate synthase activity
LU294_23880	COG4129	membrane
LU294_23885	COG1132	(ABC) transporter
LU294_23910	COG1194	a g-specific adenine glycosylase
LU294_23915	COG1988	membrane-bound metal-dependent
LU294_23945	COG1090	epimerase
LU294_23950	COG0402	S-adenosylhomocysteine deaminase activity
LU294_23970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LU294_23985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LU294_23985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LU294_23995	COG0463	Glycosyl transferase, family 2
LU294_24010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LU294_24015	COG1263	PTS System
LU294_24015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LU294_24045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LU294_24050	COG0833	amino acid
LU294_24060	COG3829	transcription factor binding
LU294_24160	COG0740	serine-type endopeptidase activity
LU294_24170	COG1802	Transcriptional regulator
LU294_24170	COG4626	Terminase
LU294_24200	COG0582	viral genome integration into host DNA
LU294_24285	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LU294_24290	COG1846	Transcriptional regulator
LU294_24310	COG3646	Phage regulatory protein
LU294_24355	COG0582	viral genome integration into host DNA
LU294_24365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LU294_24385	COG0535	radical SAM domain protein
LU294_24395	COG0387	Pfam Sodium calcium exchanger
LU294_24400	COG3871	stress protein (general stress protein 26)
LU294_24415	COG0586	Pfam SNARE associated Golgi protein
LU294_24425	COG0681	Belongs to the peptidase S26 family
LU294_24435	COG0697	spore germination
LU294_24440	COG2217	Heavy metal translocating P-type atpase
LU294_24445	COG1295	ribonuclease BN
LU294_24455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LU294_24470	COG3853	Toxic anion resistance protein (TelA)
LU294_24480	COG0861	Integral membrane protein TerC family
LU294_24485	COG2310	stress, protein
LU294_24490	COG2310	stress, protein
LU294_24495	COG2310	stress, protein
LU294_24525	COG2270	Major facilitator Superfamily
LU294_24575	COG0488	(ABC) transporter
LU294_24585	COG1116	anion transmembrane transporter activity
LU294_24595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LU294_24610	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LU294_24645	COG1263	PTS System
LU294_24645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LU294_24645	COG2190	(PTS) system
LU294_24650	COG0366	Alpha amylase catalytic
LU294_24655	COG0840	transmembrane signaling receptor activity
LU294_24660	COG0840	transmembrane signaling receptor activity
LU294_24670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LU294_24675	COG0765	amino acid transport
LU294_24685	COG0723	plastoquinol--plastocyanin reductase activity
LU294_24685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LU294_24690	COG2814	Major facilitator Superfamily
LU294_24695	COG3541	Predicted nucleotidyltransferase
LU294_24735	COG0166	Belongs to the GPI family
LU294_24750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LU294_24755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LU294_24760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LU294_24790	COG0450	alkyl hydroperoxide reductase
LU294_24805	COG1473	amidohydrolase
LU294_24810	COG1757	Na H antiporter
LU294_24835	COG4807	Protein conserved in bacteria
LU294_24840	COG5002	protein histidine kinase activity
LU294_24845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LU294_24850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LU294_24855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LU294_24870	COG2309	aminopeptidase activity
LU294_24875	COG2076	Multidrug Resistance protein
LU294_24880	COG1012	belongs to the aldehyde dehydrogenase family
LU294_24890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LU294_24895	COG0546	phosphoglycolate phosphatase activity
LU294_24900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LU294_24905	COG1597	lipid kinase activity
LU294_24925	COG4682	membrane
LU294_24930	COG1846	Transcriptional regulator
LU294_24935	COG0003	Pfam Anion-transporting ATPase
LU294_24950	COG1464	Belongs to the NlpA lipoprotein family
LU294_24955	COG2011	ABC-type metal ion transport system permease component
LU294_24960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LU294_24965	COG1335	isochorismatase
LU294_24985	COG4851	CamS sex pheromone cAM373 precursor
LU294_24995	COG0210	DNA helicase
LU294_25020	COG0151	Belongs to the GarS family
LU294_25030	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LU294_25040	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LU294_25055	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LU294_25065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LU294_25070	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LU294_25075	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LU294_25100	COG0697	spore germination
LU294_25125	COG0745	RESPONSE REGULATOR receiver
LU294_25130	COG2205	protein histidine kinase activity
LU294_25165	COG1215	transferase activity, transferring glycosyl groups
LU294_25185	COG2226	methyltransferase
LU294_25215	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LU294_25240	COG5002	protein histidine kinase activity
LU294_25250	COG2252	PERMEase
LU294_25270	COG1266	CAAX protease self-immunity
LU294_25285	COG0488	(ABC) transporter
LU294_25295	COG0456	acetyltransferase
LU294_25300	COG1214	PFAM Peptidase M22, glycoprotease
LU294_25305	COG0802	atpase or kinase
LU294_25400	COG2183	response to ionizing radiation
LU294_25405	COG2337	Toxic component of a toxin-antitoxin (TA) module
LU294_25410	COG0864	Transcriptional regulator
LU294_25415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LU294_25420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LU294_25430	COG0705	Rhomboid family
LU294_25435	COG4294	response to UV
LU294_25445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LU294_25455	COG2814	Major facilitator Superfamily
LU294_25460	COG0531	amino acid
LU294_25470	COG0179	Fumarylacetoacetate (FAA) hydrolase
LU294_25475	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LU294_25505	COG0561	phosphatase activity
LU294_25510	COG4608	Belongs to the ABC transporter superfamily
LU294_25515	COG0444	Belongs to the ABC transporter superfamily
LU294_25520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LU294_25525	COG0601	transmembrane transport
LU294_25530	COG0747	negative chemotaxis
LU294_25535	COG0747	negative chemotaxis
LU294_25545	COG0842	Transport permease protein
LU294_25550	COG0842	Transport permease protein
LU294_25550	COG1511	domain protein
LU294_25555	COG1131	(ABC) transporter
LU294_25560	COG2197	response regulator
LU294_25565	COG4585	Histidine kinase
LU294_25570	COG0488	(ABC) transporter
LU294_25595	COG5298	Protein conserved in bacteria
LU294_25600	COG0084	hydrolase, TatD family'
LU294_25610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LU294_25620	COG1609	Transcriptional regulator
LU294_25630	COG0204	Acyl-transferase
LU294_25645	COG0697	spore germination
LU294_25660	COG1910	domain protein
LU294_25665	COG0725	ABC transporter, periplasmic molybdate-binding protein
LU294_25670	COG4149	molybdate abc transporter
LU294_25685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LU294_25690	COG0656	L-ascorbic acid biosynthetic process
LU294_25695	COG4166	transmembrane transport
LU294_25700	COG4166	transmembrane transport
LU294_25715	COG2207	Transcriptional regulator
LU294_25725	COG4166	transmembrane transport
LU294_25730	COG4608	Belongs to the ABC transporter superfamily
LU294_25735	COG0444	Belongs to the ABC transporter superfamily
LU294_25740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LU294_25745	COG0601	transmembrane transport
LU294_25765	COG2814	Major facilitator Superfamily
LU294_25775	COG2271	Major facilitator Superfamily
LU294_25780	COG0277	FAD linked oxidase domain protein
LU294_25790	COG0604	alcohol dehydrogenase
LU294_25795	COG1464	Belongs to the NlpA lipoprotein family
LU294_25805	COG2011	ABC-type metal ion transport system permease component
LU294_25810	COG1028	Short-chain dehydrogenase reductase Sdr
LU294_25835	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LU294_25855	COG0596	Alpha beta hydrolase
LU294_25875	COG4856	YbbR-like protein
LU294_25880	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LU294_25960	COG0726	polysaccharide deacetylase
LU294_25965	COG2194	sulfuric ester hydrolase activity
LU294_25975	COG0489	protein tyrosine kinase activity
LU294_25980	COG0860	N-Acetylmuramoyl-L-alanine amidase
LU294_26005	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LU294_26035	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LU294_26040	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LU294_26050	COG0024	Methionine aminopeptidase
LU294_26060	COG0201	protein transport
LU294_26120	COG0255	Belongs to the universal ribosomal protein uL29 family
LU294_26190	COG1358	cellular component organization or biogenesis
LU294_26205	COG2813	Specifically methylates the guanine in position
LU294_26225	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LU294_26230	COG0250	Participates in transcription elongation, termination and antitermination
LU294_26235	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LU294_26250	COG3688	RNA-binding protein containing a PIN domain
LU294_26255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LU294_26270	COG1045	serine acetyltransferase
LU294_26290	COG4956	integral membrane protein (PIN domain superfamily)
LU294_26300	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LU294_26305	COG0542	response to heat
LU294_26315	COG3880	PFAM UvrB UvrC protein
LU294_26405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LU294_26410	COG1396	sequence-specific DNA binding
LU294_26415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LU294_26420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LU294_26425	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LU294_26430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LU294_26435	COG0512	Glutamine amidotransferase of anthranilate synthase
LU294_26440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LU294_26445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LU294_26460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LU294_26465	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LU294_26475	COG2208	phosphoserine phosphatase activity
LU294_26490	COG1098	S1 RNA binding domain
LU294_26510	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LU294_26515	COG3956	TIGRFAM MazG family protein
LU294_26520	COG2244	polysaccharide biosynthetic process
LU294_26525	COG2002	toxin-antitoxin pair type II binding
LU294_26530	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LU294_26560	COG0251	oxidation-reduction process
LU294_26565	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LU294_26580	COG4466	Protein conserved in bacteria
LU294_26595	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LU294_26600	COG0084	hydrolase, TatD family'
LU294_26605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LU294_26605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LU294_26610	COG2002	toxin-antitoxin pair type II binding
LU294_26615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LU294_26625	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LU294_26635	COG1774	PSP1 C-terminal conserved region
LU294_26640	COG0470	DNA polymerase III
LU294_26650	COG1982	Orn Lys Arg decarboxylase major
LU294_26705	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LU294_26715	COG0590	tRNA wobble adenosine to inosine editing
LU294_26720	COG1335	isochorismatase
LU294_26725	COG1428	Deoxynucleoside kinase
LU294_26730	COG1428	Deoxynucleoside kinase
LU294_26760	COG1686	Belongs to the peptidase S11 family
LU294_26765	COG0516	GMP reductase activity
LU294_26765	COG0517	IMP dehydrogenase activity
LU294_26800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LU294_26805	COG0187	DNA topoisomerase II activity
LU294_26815	COG2501	S4 domain
LU294_26820	COG0592	DNA-directed DNA polymerase activity
LU294_26825	COG0662	Cupin 2, conserved barrel domain protein