locus-tag	class	description
B5S_0006	COG1876	peptidase activity
B5S_0015	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B5S_0021	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B5S_0123	COG1674	ftsk spoiiie
B5S_0179	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B5S_0195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B5S_0195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B5S_0206	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B5S_0208	COG0716	FMN binding
B5S_0209	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B5S_0213	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B5S_0219	COG0756	dUTP diphosphatase activity
B5S_0222	COG0419	ATPase involved in DNA repair
B5S_0231	COG0513	Belongs to the DEAD box helicase family
B5S_0243	COG0791	NLP P60 protein
B5S_0243	COG3883	PFAM NLP P60 protein
B5S_0244	COG4193	domain, Protein
B5S_0244	COG5263	repeat protein
B5S_0248	COG3584	3D domain protein
B5S_0248	COG1388	LysM domain