BUBS_75 c1c0ed335e30a0ba572a4dc688433e18 275 SUPERFAMILY SSF55846 21 157 6.24E-41 T 30-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 BUBS_75 c1c0ed335e30a0ba572a4dc688433e18 275 Pfam PF08460 Bacterial SH3 domain 198 253 2.7E-7 T 30-10-2018 IPR003646 SH3-like domain, bacterial-type BUBS_75 c1c0ed335e30a0ba572a4dc688433e18 275 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 25 142 1.7E-17 T 30-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 BUBS_75 c1c0ed335e30a0ba572a4dc688433e18 275 Gene3D G3DSA:3.40.80.10 15 166 5.5E-40 T 30-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 BUBS_75 c1c0ed335e30a0ba572a4dc688433e18 275 SMART SM00287 199 265 1.2E-12 T 30-10-2018 IPR003646 SH3-like domain, bacterial-type BUBS_75 c1c0ed335e30a0ba572a4dc688433e18 275 Gene3D G3DSA:2.30.30.410 179 275 3.7E-11 T 30-10-2018 BUBS_75 c1c0ed335e30a0ba572a4dc688433e18 275 SMART SM00644 10 151 3.5E-32 T 30-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 BUBS_140 e93a7108316ae512144299922c9d5dd5 784 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 166 243 7.6E-8 T 30-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BUBS_140 e93a7108316ae512144299922c9d5dd5 784 PRINTS PR01183 Ribonucleotide reductase large chain signature 321 340 2.3E-19 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BUBS_140 e93a7108316ae512144299922c9d5dd5 784 PRINTS PR01183 Ribonucleotide reductase large chain signature 526 549 2.3E-19 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BUBS_140 e93a7108316ae512144299922c9d5dd5 784 PRINTS PR01183 Ribonucleotide reductase large chain signature 472 483 2.3E-19 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BUBS_140 e93a7108316ae512144299922c9d5dd5 784 PRINTS PR01183 Ribonucleotide reductase large chain signature 652 679 2.3E-19 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BUBS_140 e93a7108316ae512144299922c9d5dd5 784 PRINTS PR01183 Ribonucleotide reductase large chain signature 564 586 2.3E-19 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BUBS_140 e93a7108316ae512144299922c9d5dd5 784 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 169 770 1.6E-120 T 30-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BUBS_140 e93a7108316ae512144299922c9d5dd5 784 SUPERFAMILY SSF51998 245 772 5.49E-116 T 30-10-2018 BUBS_140 e93a7108316ae512144299922c9d5dd5 784 Gene3D G3DSA:1.10.1650.20 364 434 3.0E-152 T 30-10-2018 BUBS_140 e93a7108316ae512144299922c9d5dd5 784 SUPERFAMILY SSF48168 42 243 2.35E-31 T 30-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BUBS_140 e93a7108316ae512144299922c9d5dd5 784 Gene3D G3DSA:3.20.70.20 231 768 3.0E-152 T 30-10-2018 BUBS_140 e93a7108316ae512144299922c9d5dd5 784 Pfam PF02867 Ribonucleotide reductase, barrel domain 246 767 1.1E-99 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BUBS_134 2c391317127cdaa9900581a9e8b56393 270 Pfam PF00692 dUTPase 33 105 1.1E-4 T 30-10-2018 IPR029054 dUTPase-like BUBS_134 2c391317127cdaa9900581a9e8b56393 270 SUPERFAMILY SSF51283 12 105 1.07E-13 T 30-10-2018 IPR036157 dUTPase-like superfamily BUBS_134 2c391317127cdaa9900581a9e8b56393 270 SUPERFAMILY SSF51283 216 269 2.88E-8 T 30-10-2018 IPR036157 dUTPase-like superfamily BUBS_208 8be879e8cf5b02b48d22c95e393f6dd1 100 Gene3D G3DSA:1.10.287.1080 7 100 3.1E-10 T 30-10-2018 BUBS_208 8be879e8cf5b02b48d22c95e393f6dd1 100 SUPERFAMILY SSF101386 19 99 2.78E-9 T 30-10-2018 BUBS_208 8be879e8cf5b02b48d22c95e393f6dd1 100 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 21 98 5.7E-5 T 30-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core BUBS_64 76b396464e1489b5a23934d447cd5c10 300 Gene3D G3DSA:3.30.572.10 5 295 4.6E-99 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 BUBS_64 76b396464e1489b5a23934d447cd5c10 300 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 18 295 4.1E-86 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 BUBS_64 76b396464e1489b5a23934d447cd5c10 300 Pfam PF00303 Thymidylate synthase 19 295 1.4E-89 T 30-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 BUBS_64 76b396464e1489b5a23934d447cd5c10 300 PRINTS PR00108 Thymidylate synthase family signature 145 164 4.2E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 BUBS_64 76b396464e1489b5a23934d447cd5c10 300 PRINTS PR00108 Thymidylate synthase family signature 54 75 4.2E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 BUBS_64 76b396464e1489b5a23934d447cd5c10 300 PRINTS PR00108 Thymidylate synthase family signature 171 186 4.2E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 BUBS_64 76b396464e1489b5a23934d447cd5c10 300 PRINTS PR00108 Thymidylate synthase family signature 190 216 4.2E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 BUBS_64 76b396464e1489b5a23934d447cd5c10 300 PRINTS PR00108 Thymidylate synthase family signature 228 245 4.2E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 BUBS_64 76b396464e1489b5a23934d447cd5c10 300 Hamap MF_00008 Thymidylate synthase [thyA]. 13 295 30.68 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 BUBS_64 76b396464e1489b5a23934d447cd5c10 300 SUPERFAMILY SSF55831 5 295 3.01E-95 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 BUBS_129 1ef18484b12e1f70e27a3fb94121b9c9 629 SUPERFAMILY SSF52540 365 621 4.15E-20 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase BUBS_129 1ef18484b12e1f70e27a3fb94121b9c9 629 SUPERFAMILY SSF75712 278 358 4.18E-7 T 30-10-2018 BUBS_129 1ef18484b12e1f70e27a3fb94121b9c9 629 Gene3D G3DSA:3.40.50.300 1 225 6.1E-21 T 30-10-2018 BUBS_129 1ef18484b12e1f70e27a3fb94121b9c9 629 SUPERFAMILY SSF52540 1 615 1.06E-14 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase BUBS_129 1ef18484b12e1f70e27a3fb94121b9c9 629 Gene3D G3DSA:3.40.50.300 328 625 6.4E-29 T 30-10-2018 BUBS_58 41d4dc145284a2c8cf14876722a8fd86 166 Pfam PF00186 Dihydrofolate reductase 3 164 1.4E-48 T 30-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 BUBS_58 41d4dc145284a2c8cf14876722a8fd86 166 SUPERFAMILY SSF53597 2 165 5.61E-47 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 BUBS_58 41d4dc145284a2c8cf14876722a8fd86 166 Gene3D G3DSA:3.40.430.10 1 166 1.5E-48 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 BUBS_58 41d4dc145284a2c8cf14876722a8fd86 166 PRINTS PR00070 Dihydrofolate reductase signature 41 52 1.6E-7 T 30-10-2018 BUBS_58 41d4dc145284a2c8cf14876722a8fd86 166 PRINTS PR00070 Dihydrofolate reductase signature 94 108 1.6E-7 T 30-10-2018 BUBS_58 41d4dc145284a2c8cf14876722a8fd86 166 PRINTS PR00070 Dihydrofolate reductase signature 28 36 1.6E-7 T 30-10-2018 BUBS_124 ad92100a0165c83284ed0dfe01b4a6a1 492 SUPERFAMILY SSF52540 172 415 2.87E-25 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase BUBS_124 ad92100a0165c83284ed0dfe01b4a6a1 492 SMART SM00382 191 414 3.4E-5 T 30-10-2018 IPR003593 AAA+ ATPase domain BUBS_124 ad92100a0165c83284ed0dfe01b4a6a1 492 Gene3D G3DSA:3.40.50.300 149 422 3.9E-40 T 30-10-2018 BUBS_124 ad92100a0165c83284ed0dfe01b4a6a1 492 Pfam PF03796 DnaB-like helicase C terminal domain 174 361 1.0E-16 T 30-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 BUBS_188 1dbd46266e04cc28db4602324cc1d15f 97 Pfam PF04688 SPP1 phage holin 16 88 9.6E-13 T 30-10-2018 IPR006479 Holin BUBS_188 1dbd46266e04cc28db4602324cc1d15f 97 ProDom PD008023 HOLIN TRANSMEMBRANE MEMBRANE PROPHAGE FAMILY BHLB SPP1 5'REGION HOLIN ORF050 19 84 4.0E-4 T 30-10-2018 IPR006479 Holin BUBS_240 76f8cff1f4c53decda904201bc403ade 246 Gene3D G3DSA:3.60.15.10 5 241 2.7E-25 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like BUBS_240 76f8cff1f4c53decda904201bc403ade 246 Pfam PF12706 Beta-lactamase superfamily domain 29 219 6.7E-15 T 30-10-2018 IPR001279 Metallo-beta-lactamase BUBS_240 76f8cff1f4c53decda904201bc403ade 246 SMART SM00849 17 219 7.0E-4 T 30-10-2018 IPR001279 Metallo-beta-lactamase BUBS_240 76f8cff1f4c53decda904201bc403ade 246 SUPERFAMILY SSF56281 2 226 2.88E-28 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like BUBS_194 c87f060ef18d23140f529e1411a9a50e 425 SUPERFAMILY SSF56300 162 382 3.35E-10 T 30-10-2018 BUBS_194 c87f060ef18d23140f529e1411a9a50e 425 Gene3D G3DSA:3.60.21.10 161 389 6.1E-6 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like BUBS_106 13aa03f8562b545313ee359f6edefa84 1265 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 1100 1209 2.5E-14 T 30-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 BUBS_106 13aa03f8562b545313ee359f6edefa84 1265 SMART SM00047 1086 1219 3.6E-7 T 30-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 BUBS_106 13aa03f8562b545313ee359f6edefa84 1265 Gene3D G3DSA:1.10.530.10 1093 1211 2.7E-13 T 30-10-2018 BUBS_143 63f444caaccba3fde55ed67544f8f810 369 Gene3D G3DSA:1.10.620.20 31 332 1.3E-68 T 30-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 BUBS_143 63f444caaccba3fde55ed67544f8f810 369 Pfam PF00268 Ribonucleotide reductase, small chain 42 322 9.0E-44 T 30-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BUBS_143 63f444caaccba3fde55ed67544f8f810 369 SUPERFAMILY SSF47240 33 332 6.38E-56 T 30-10-2018 IPR009078 Ferritin-like superfamily BUBS_164 35bba0c51e4c815f515cdb608228b330 226 Pfam PF00476 DNA polymerase family A 8 165 2.2E-25 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BUBS_164 35bba0c51e4c815f515cdb608228b330 226 PRINTS PR00868 DNA-polymerase family A (pol I) signature 43 54 2.9E-7 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BUBS_164 35bba0c51e4c815f515cdb608228b330 226 PRINTS PR00868 DNA-polymerase family A (pol I) signature 75 91 2.9E-7 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BUBS_164 35bba0c51e4c815f515cdb608228b330 226 PRINTS PR00868 DNA-polymerase family A (pol I) signature 105 118 2.9E-7 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BUBS_164 35bba0c51e4c815f515cdb608228b330 226 PRINTS PR00868 DNA-polymerase family A (pol I) signature 21 32 2.9E-7 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BUBS_164 35bba0c51e4c815f515cdb608228b330 226 Gene3D G3DSA:1.10.150.20 3 82 2.4E-28 T 30-10-2018 BUBS_164 35bba0c51e4c815f515cdb608228b330 226 SUPERFAMILY SSF56672 4 168 1.67E-31 T 30-10-2018 BUBS_164 35bba0c51e4c815f515cdb608228b330 226 SMART SM00482 1 122 5.7E-4 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BUBS_164 35bba0c51e4c815f515cdb608228b330 226 Gene3D G3DSA:3.30.70.370 83 162 2.4E-28 T 30-10-2018 BUBS_232 30e8dbb1faad6501e07bf4956640f021 312 Gene3D G3DSA:1.20.140.160 131 254 4.0E-13 T 30-10-2018 BUBS_232 30e8dbb1faad6501e07bf4956640f021 312 SUPERFAMILY SSF88659 191 253 3.74E-11 T 30-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like BUBS_232 30e8dbb1faad6501e07bf4956640f021 312 Pfam PF04545 Sigma-70, region 4 202 251 1.4E-7 T 30-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 BUBS_232 30e8dbb1faad6501e07bf4956640f021 312 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 251 5.9E-16 T 30-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 BUBS_232 30e8dbb1faad6501e07bf4956640f021 312 Pfam PF04542 Sigma-70 region 2 42 110 7.9E-8 T 30-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 BUBS_232 30e8dbb1faad6501e07bf4956640f021 312 SUPERFAMILY SSF88946 25 116 2.83E-12 T 30-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 BUBS_232 30e8dbb1faad6501e07bf4956640f021 312 Gene3D G3DSA:1.10.1740.10 21 109 9.6E-6 T 30-10-2018 BUBS_115 c2f8f4473888d335411a6f4f321e3d05 250 Gene3D G3DSA:3.10.450.40 126 243 3.1E-11 T 30-10-2018 BUBS_115 c2f8f4473888d335411a6f4f321e3d05 250 SUPERFAMILY SSF160719 140 237 9.42E-14 T 30-10-2018 BUBS_115 c2f8f4473888d335411a6f4f321e3d05 250 Pfam PF10934 Protein of unknown function (DUF2634) 137 224 1.7E-8 T 30-10-2018 IPR020288 Protein of unknown function DUF2634 BUBS_103 9f3e45e8de92cb413e14cb6c2f4da365 242 Gene3D G3DSA:2.40.40.10 122 224 3.3E-6 T 30-10-2018 IPR036908 RlpA-like domain superfamily BUBS_103 9f3e45e8de92cb413e14cb6c2f4da365 242 SUPERFAMILY SSF158634 73 122 6.93E-5 T 30-10-2018 BUBS_103 9f3e45e8de92cb413e14cb6c2f4da365 242 SUPERFAMILY SSF50685 174 222 1.64E-8 T 30-10-2018 IPR036908 RlpA-like domain superfamily BUBS_103 9f3e45e8de92cb413e14cb6c2f4da365 242 Pfam PF06725 3D domain 181 242 4.6E-21 T 30-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 BUBS_183 b06f0c332b11762087db0c712ddb79a5 417 PRINTS PR00142 RecA protein signature 99 128 2.3E-7 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BUBS_183 b06f0c332b11762087db0c712ddb79a5 417 PRINTS PR00142 RecA protein signature 230 258 2.3E-7 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BUBS_183 b06f0c332b11762087db0c712ddb79a5 417 PRINTS PR00142 RecA protein signature 267 296 2.3E-7 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BUBS_183 b06f0c332b11762087db0c712ddb79a5 417 Gene3D G3DSA:3.40.50.300 41 357 4.4E-61 T 30-10-2018 BUBS_183 b06f0c332b11762087db0c712ddb79a5 417 SUPERFAMILY SSF52540 40 291 1.17E-24 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase BUBS_183 b06f0c332b11762087db0c712ddb79a5 417 Pfam PF00154 recA bacterial DNA recombination protein 52 291 5.6E-30 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BUBS_118 2f8e0808feceed91afae12b5a1096b69 1203 Pfam PF16075 Domain of unknown function (DUF4815) 11 634 4.8E-126 T 30-10-2018 IPR032096 Domain of unknown function DUF4815 BUBS_132 24c1efca64a31a4fd755af6fb2994ea5 358 SUPERFAMILY SSF57783 8 77 1.55E-11 T 30-10-2018 BUBS_132 24c1efca64a31a4fd755af6fb2994ea5 358 Gene3D G3DSA:3.40.1360.10 230 346 4.2E-6 T 30-10-2018 BUBS_132 24c1efca64a31a4fd755af6fb2994ea5 358 Pfam PF12760 Transposase zinc-ribbon domain 21 51 9.1E-7 T 30-10-2018 IPR024442 Transposase, zinc-ribbon BUBS_132 24c1efca64a31a4fd755af6fb2994ea5 358 Gene3D G3DSA:3.90.580.10 2 82 2.6E-8 T 30-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 BUBS_132 24c1efca64a31a4fd755af6fb2994ea5 358 SUPERFAMILY SSF56731 140 344 7.59E-12 T 30-10-2018 BUBS_77 ae2db6438acdf5215f4f8744f2a5d292 599 Gene3D G3DSA:3.40.50.300 47 231 1.3E-11 T 30-10-2018 BUBS_77 ae2db6438acdf5215f4f8744f2a5d292 599 Pfam PF05876 Phage terminase large subunit (GpA) 63 427 1.4E-26 T 30-10-2018 IPR008866 Bacteriophage lambda, GpA BUBS_120 9c76361d9beb75ce47bf44dfce236773 589 Gene3D G3DSA:3.40.50.300 403 589 1.4E-33 T 30-10-2018 BUBS_120 9c76361d9beb75ce47bf44dfce236773 589 Gene3D G3DSA:3.40.50.300 100 233 2.8E-9 T 30-10-2018 BUBS_120 9c76361d9beb75ce47bf44dfce236773 589 Gene3D G3DSA:3.40.50.300 277 387 3.4E-9 T 30-10-2018 BUBS_120 9c76361d9beb75ce47bf44dfce236773 589 Pfam PF00271 Helicase conserved C-terminal domain 454 545 5.6E-14 T 30-10-2018 IPR001650 Helicase, C-terminal BUBS_120 9c76361d9beb75ce47bf44dfce236773 589 SUPERFAMILY SSF52540 321 559 1.17E-24 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase BUBS_120 9c76361d9beb75ce47bf44dfce236773 589 Pfam PF04851 Type III restriction enzyme, res subunit 129 366 4.0E-10 T 30-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 BUBS_120 9c76361d9beb75ce47bf44dfce236773 589 SUPERFAMILY SSF52540 25 384 9.31E-17 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase BUBS_120 9c76361d9beb75ce47bf44dfce236773 589 SMART SM00490 465 546 2.6E-16 T 30-10-2018 IPR001650 Helicase, C-terminal BUBS_72 50f92e821963c1bed8ce21c5555993ee 130 SUPERFAMILY SSF56784 26 114 1.2E-12 T 30-10-2018 IPR036412 HAD-like superfamily BUBS_72 50f92e821963c1bed8ce21c5555993ee 130 Gene3D G3DSA:3.40.50.1000 22 130 5.3E-20 T 30-10-2018 IPR023214 HAD superfamily BUBS_74 c84e7bc0847c2fc4b4c93af192ea41b8 278 Gene3D G3DSA:3.40.50.2020 2 128 3.5E-9 T 30-10-2018 BUBS_74 c84e7bc0847c2fc4b4c93af192ea41b8 278 SUPERFAMILY SSF53271 89 240 5.35E-8 T 30-10-2018 IPR029057 Phosphoribosyltransferase-like BUBS_74 c84e7bc0847c2fc4b4c93af192ea41b8 278 Gene3D G3DSA:3.40.50.2020 129 277 9.2E-13 T 30-10-2018 BUBS_162 093a4115cdd268005256aacbd3bb5ed8 826 Pfam PF00476 DNA polymerase family A 572 804 9.9E-38 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BUBS_162 093a4115cdd268005256aacbd3bb5ed8 826 Gene3D G3DSA:3.30.70.370 694 745 2.4E-27 T 30-10-2018 BUBS_162 093a4115cdd268005256aacbd3bb5ed8 826 Gene3D G3DSA:1.10.150.20 746 805 2.4E-27 T 30-10-2018 BUBS_162 093a4115cdd268005256aacbd3bb5ed8 826 SUPERFAMILY SSF56672 493 805 5.11E-52 T 30-10-2018 BUBS_162 093a4115cdd268005256aacbd3bb5ed8 826 Gene3D G3DSA:3.40.470.10 25 179 1.9E-12 T 30-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BUBS_162 093a4115cdd268005256aacbd3bb5ed8 826 SUPERFAMILY SSF52141 31 176 5.43E-5 T 30-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BUBS_162 093a4115cdd268005256aacbd3bb5ed8 826 SUPERFAMILY SSF53098 189 331 1.95E-17 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily BUBS_162 093a4115cdd268005256aacbd3bb5ed8 826 Pfam PF01612 3'-5' exonuclease 193 353 2.6E-12 T 30-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 BUBS_162 093a4115cdd268005256aacbd3bb5ed8 826 PRINTS PR00868 DNA-polymerase family A (pol I) signature 737 760 2.0E-20 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BUBS_162 093a4115cdd268005256aacbd3bb5ed8 826 PRINTS PR00868 DNA-polymerase family A (pol I) signature 685 707 2.0E-20 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BUBS_162 093a4115cdd268005256aacbd3bb5ed8 826 PRINTS PR00868 DNA-polymerase family A (pol I) signature 767 780 2.0E-20 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BUBS_162 093a4115cdd268005256aacbd3bb5ed8 826 PRINTS PR00868 DNA-polymerase family A (pol I) signature 791 816 2.0E-20 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BUBS_60 96eb5043b6515e11c47d9d1c9034e231 101 SUPERFAMILY SSF57997 4 99 1.57E-8 T 30-10-2018 BUBS_60 96eb5043b6515e11c47d9d1c9034e231 101 Gene3D G3DSA:1.20.5.340 2 101 5.7E-10 T 30-10-2018 BUBS_126 364f1df948c3c61e179a218dee316ddd 365 SUPERFAMILY SSF56300 5 305 1.31E-26 T 30-10-2018 BUBS_126 364f1df948c3c61e179a218dee316ddd 365 Pfam PF00149 Calcineurin-like phosphoesterase 4 215 2.6E-9 T 30-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 BUBS_126 364f1df948c3c61e179a218dee316ddd 365 Gene3D G3DSA:3.60.21.10 4 264 7.7E-34 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like BUBS_107 2f0555a27136d8dbc60d07b607b2b748 725 Gene3D G3DSA:3.90.1720.10 539 718 1.0E-20 T 30-10-2018 BUBS_107 2f0555a27136d8dbc60d07b607b2b748 725 SUPERFAMILY SSF54001 581 721 5.89E-17 T 30-10-2018 IPR038765 Papain-like cysteine peptidase superfamily BUBS_107 2f0555a27136d8dbc60d07b607b2b748 725 Pfam PF00877 NlpC/P60 family 597 718 2.1E-16 T 30-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain BUBS_154 fa2011f8cd0e6793f688bd5c1d1c3103 108 Pfam PF00216 Bacterial DNA-binding protein 6 90 6.1E-10 T 30-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 BUBS_154 fa2011f8cd0e6793f688bd5c1d1c3103 108 Gene3D G3DSA:4.10.520.10 5 99 1.4E-6 T 30-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 BUBS_154 fa2011f8cd0e6793f688bd5c1d1c3103 108 SUPERFAMILY SSF47729 5 90 1.34E-9 T 30-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 BUBS_89 cfb0a94a77c97c0c8fcced23ca636098 268 Pfam PF04586 Caudovirus prohead serine protease 38 175 1.2E-4 T 30-10-2018 IPR006433 Prohead protease BUBS_138 c63e54ddf770f712626c51839bcbb7a7 187 ProDom PD927567 D14 PHAGE GP54 SPO1 GENE ORF78 ORF063 ORF064 11 135 3.0E-20 T 30-10-2018 BUBS_144 5659182c3190de1006f411accf8c51d0 159 Gene3D G3DSA:3.40.50.360 1 143 5.0E-11 T 30-10-2018 IPR029039 Flavoprotein-like superfamily BUBS_144 5659182c3190de1006f411accf8c51d0 159 SUPERFAMILY SSF52218 1 121 7.24E-11 T 30-10-2018 IPR029039 Flavoprotein-like superfamily BUBS_163 241c1062137a3b4bf80ea290b1e6e2e8 228 SUPERFAMILY SSF64496 185 226 2.56E-8 T 30-10-2018 BUBS_163 241c1062137a3b4bf80ea290b1e6e2e8 228 Gene3D G3DSA:1.10.10.10 175 227 2.3E-10 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily BUBS_163 241c1062137a3b4bf80ea290b1e6e2e8 228 Gene3D G3DSA:1.10.10.10 117 166 7.3E-7 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily BUBS_61 7a9a7417f5cb87c0a6370b572282acf0 220 Pfam PF13238 AAA domain 19 181 3.5E-10 T 30-10-2018 BUBS_61 7a9a7417f5cb87c0a6370b572282acf0 220 Gene3D G3DSA:3.40.50.300 19 215 2.3E-25 T 30-10-2018 BUBS_61 7a9a7417f5cb87c0a6370b572282acf0 220 SUPERFAMILY SSF52540 18 213 2.43E-12 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase BUBS_147 a3feab0cebaaf50d9d4be80d348d1514 92 Pfam PF00085 Thioredoxin 4 73 5.6E-5 T 30-10-2018 IPR013766 Thioredoxin domain GO:0045454 BUBS_147 a3feab0cebaaf50d9d4be80d348d1514 92 SUPERFAMILY SSF52833 4 69 6.74E-8 T 30-10-2018 IPR036249 Thioredoxin-like superfamily BUBS_147 a3feab0cebaaf50d9d4be80d348d1514 92 Gene3D G3DSA:3.40.30.10 2 87 5.9E-7 T 30-10-2018 BUBS_122 26e83aaa9814cb16d84b4f7f7e19f811 599 SUPERFAMILY SSF46785 25 78 7.89E-5 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily BUBS_73 79f3af249e9d00530a52e0c0a3c502a6 495 Gene3D G3DSA:3.20.20.70 150 429 1.5E-89 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 BUBS_73 79f3af249e9d00530a52e0c0a3c502a6 495 PIRSF PIRSF005943 1 495 1.2E-157 T 30-10-2018 IPR016471 Nicotinamide phosphoribosyl transferase Reactome: R-HSA-1368108|Reactome: R-HSA-197264 BUBS_73 79f3af249e9d00530a52e0c0a3c502a6 495 SUPERFAMILY SSF51690 154 492 2.88E-31 T 30-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 BUBS_73 79f3af249e9d00530a52e0c0a3c502a6 495 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 186 475 5.5E-42 T 30-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 BUBS_116 665078fd0079c58c7177da5c6f5810e7 348 Pfam PF04865 Baseplate J-like protein 66 306 3.5E-33 T 30-10-2018 IPR006949 Baseplate protein J-like BUBS_85 dd8817f5d3b23f1abb0b635291e974cd 278 SUPERFAMILY SSF51126 15 219 1.3E-6 T 30-10-2018 IPR011050 Pectin lyase fold/virulence factor BUBS_228 3e0cf5cdf9097b0ce7c27405879f6796 257 Gene3D G3DSA:1.10.10.60 112 155 2.4E-5 T 30-10-2018 BUBS_228 3e0cf5cdf9097b0ce7c27405879f6796 257 Gene3D G3DSA:1.10.10.60 49 99 1.9E-5 T 30-10-2018 BUBS_87 c34e936a5a80390d51e3b0e82ca4345d 563 Pfam PF04860 Phage portal protein 162 462 3.1E-21 T 30-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein