locus-tag	class	description
HOBO_116	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
HOBO_124	COG0756	dUTP diphosphatase activity
HOBO_129	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOBO_132	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOBO_143	COG0270	DNA (cytosine-5-)-methyltransferase activity
HOBO_145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOBO_145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOBO_150	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HOBO_162	COG2226	methyltransferase
HOBO_202	COG1191	sigma factor activity
HOBO_212	COG1674	ftsk spoiiie
HOBO_234	COG1234	tRNA 3'-trailer cleavage
HOBO_24	COG1690	Belongs to the RtcB family
HOBO_240	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HOBO_240	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HOBO_38	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HOBO_41	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HOBO_45	COG1702	phosphate starvation-inducible protein PhoH
HOBO_93	COG1388	LysM domain
HOBO_93	COG3584	3D domain protein
HOBO_98	COG0791	NLP P60 protein
HOBO_98	COG3883	PFAM NLP P60 protein