JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 Gene3D G3DSA:3.30.420.10 188 400 2.7E-28 T 30-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 Pfam PF01612 3'-5' exonuclease 199 347 5.6E-13 T 30-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 Gene3D G3DSA:3.30.70.370 692 943 2.8E-65 T 30-10-2018 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 SMART SM00474 189 389 7.6E-4 T 30-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 SMART SM00482 723 927 7.5E-37 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 735 758 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 910 923 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 880 896 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 765 778 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 789 814 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 826 837 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 683 705 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 SUPERFAMILY SSF56672 491 973 2.56E-95 T 30-10-2018 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 Gene3D G3DSA:3.40.470.10 16 178 7.1E-14 T 30-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 SUPERFAMILY SSF53098 202 331 1.52E-19 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 Pfam PF00476 DNA polymerase family A 565 970 4.2E-70 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 JANET_166 f760cf1e28c30af32f15ea9939ef3318 1032 Gene3D G3DSA:1.10.150.20 744 887 2.8E-65 T 30-10-2018 JANET_224 c49f44b6b566789da38de0afea7c6f78 241 Pfam PF12706 Beta-lactamase superfamily domain 31 219 4.5E-16 T 30-10-2018 IPR001279 Metallo-beta-lactamase JANET_224 c49f44b6b566789da38de0afea7c6f78 241 SUPERFAMILY SSF56281 4 229 1.7E-26 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like JANET_224 c49f44b6b566789da38de0afea7c6f78 241 SMART SM00849 18 220 3.9E-10 T 30-10-2018 IPR001279 Metallo-beta-lactamase JANET_224 c49f44b6b566789da38de0afea7c6f78 241 Gene3D G3DSA:3.60.15.10 5 240 4.2E-27 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like JANET_237 35fc4bc2f1e854b8af1ecae243cdf7ff 752 Gene3D G3DSA:3.40.50.300 394 665 1.3E-78 T 30-10-2018 JANET_237 35fc4bc2f1e854b8af1ecae243cdf7ff 752 SMART SM00382 434 600 4.4E-6 T 30-10-2018 IPR003593 AAA+ ATPase domain JANET_237 35fc4bc2f1e854b8af1ecae243cdf7ff 752 Pfam PF01580 FtsK/SpoIIIE family 397 549 1.3E-37 T 30-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 JANET_237 35fc4bc2f1e854b8af1ecae243cdf7ff 752 SUPERFAMILY SSF52540 403 649 1.66E-29 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase JANET_54 409affe449288e61991c0213c67d3d1e 465 Pfam PF14284 PcfJ-like protein 314 451 3.7E-29 T 30-10-2018 IPR025586 PcfJ-like protein JANET_43 9b271e01831b9a40443c9764d09ae2d4 166 Pfam PF00186 Dihydrofolate reductase 3 163 9.6E-46 T 30-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 JANET_43 9b271e01831b9a40443c9764d09ae2d4 166 PRINTS PR00070 Dihydrofolate reductase signature 94 108 1.8E-5 T 30-10-2018 JANET_43 9b271e01831b9a40443c9764d09ae2d4 166 PRINTS PR00070 Dihydrofolate reductase signature 28 36 1.8E-5 T 30-10-2018 JANET_43 9b271e01831b9a40443c9764d09ae2d4 166 PRINTS PR00070 Dihydrofolate reductase signature 41 52 1.8E-5 T 30-10-2018 JANET_43 9b271e01831b9a40443c9764d09ae2d4 166 Gene3D G3DSA:3.40.430.10 1 166 5.0E-46 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 JANET_43 9b271e01831b9a40443c9764d09ae2d4 166 SUPERFAMILY SSF53597 1 160 8.41E-44 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 JANET_117 290a27fb9d3c28569a1fac1045aa01ce 594 Gene3D G3DSA:1.10.10.10 26 93 7.5E-6 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily JANET_117 290a27fb9d3c28569a1fac1045aa01ce 594 Pfam PF08279 HTH domain 48 83 3.4E-5 T 30-10-2018 IPR013196 Helix-turn-helix, type 11 JANET_117 290a27fb9d3c28569a1fac1045aa01ce 594 SUPERFAMILY SSF46785 48 90 1.08E-5 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily JANET_33 71346b07ac3de5764b6081a3c4392e09 87 SUPERFAMILY SSF57850 4 62 3.36E-5 T 30-10-2018 JANET_110 c0b9039672dee642a9f5593a5d9f7d4b 239 SUPERFAMILY SSF160719 128 224 5.75E-15 T 30-10-2018 JANET_110 c0b9039672dee642a9f5593a5d9f7d4b 239 Gene3D G3DSA:3.10.350.10 8 65 6.7E-6 T 30-10-2018 IPR036779 LysM domain superfamily JANET_110 c0b9039672dee642a9f5593a5d9f7d4b 239 Gene3D G3DSA:3.10.450.40 119 232 1.8E-9 T 30-10-2018 JANET_229 59d0053a9dbe27bfefffdcb7cbe6cf43 357 Gene3D G3DSA:3.30.420.40 181 317 1.1E-31 T 30-10-2018 JANET_229 59d0053a9dbe27bfefffdcb7cbe6cf43 357 SUPERFAMILY SSF53067 187 333 5.61E-11 T 30-10-2018 JANET_229 59d0053a9dbe27bfefffdcb7cbe6cf43 357 Gene3D G3DSA:3.30.420.40 11 333 1.1E-31 T 30-10-2018 JANET_229 59d0053a9dbe27bfefffdcb7cbe6cf43 357 SUPERFAMILY SSF53067 11 174 7.77E-16 T 30-10-2018 JANET_128 ec54d9884eee82cd811264306e0febae 192 Gene3D G3DSA:3.90.75.20 1 121 3.6E-33 T 30-10-2018 JANET_128 ec54d9884eee82cd811264306e0febae 192 SUPERFAMILY SSF54060 1 116 1.41E-26 T 30-10-2018 JANET_128 ec54d9884eee82cd811264306e0febae 192 Pfam PF13392 HNH endonuclease 70 115 2.2E-10 T 30-10-2018 IPR003615 HNH nuclease JANET_128 ec54d9884eee82cd811264306e0febae 192 Pfam PF07463 NUMOD4 motif 2 59 4.7E-11 T 30-10-2018 IPR010902 NUMOD4 GO:0016788 JANET_146 d2b00428e42539b2d8157aedeb00c2cc 150 SUPERFAMILY SSF52218 6 122 4.04E-11 T 30-10-2018 IPR029039 Flavoprotein-like superfamily JANET_146 d2b00428e42539b2d8157aedeb00c2cc 150 Pfam PF00258 Flavodoxin 44 118 2.2E-6 T 30-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 JANET_146 d2b00428e42539b2d8157aedeb00c2cc 150 Gene3D G3DSA:3.40.50.360 6 148 4.2E-10 T 30-10-2018 IPR029039 Flavoprotein-like superfamily JANET_50 b6d2544bb0bd87653744d0e9f0e42f9f 294 Hamap MF_00008 Thymidylate synthase [thyA]. 5 287 33.229 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 JANET_50 b6d2544bb0bd87653744d0e9f0e42f9f 294 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 7 287 1.2E-101 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 JANET_50 b6d2544bb0bd87653744d0e9f0e42f9f 294 SUPERFAMILY SSF55831 2 287 1.03E-106 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 JANET_50 b6d2544bb0bd87653744d0e9f0e42f9f 294 Pfam PF00303 Thymidylate synthase 7 287 2.5E-96 T 30-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 JANET_50 b6d2544bb0bd87653744d0e9f0e42f9f 294 PRINTS PR00108 Thymidylate synthase family signature 220 237 6.2E-34 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 JANET_50 b6d2544bb0bd87653744d0e9f0e42f9f 294 PRINTS PR00108 Thymidylate synthase family signature 137 156 6.2E-34 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 JANET_50 b6d2544bb0bd87653744d0e9f0e42f9f 294 PRINTS PR00108 Thymidylate synthase family signature 163 178 6.2E-34 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 JANET_50 b6d2544bb0bd87653744d0e9f0e42f9f 294 PRINTS PR00108 Thymidylate synthase family signature 46 67 6.2E-34 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 JANET_50 b6d2544bb0bd87653744d0e9f0e42f9f 294 PRINTS PR00108 Thymidylate synthase family signature 182 208 6.2E-34 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 JANET_50 b6d2544bb0bd87653744d0e9f0e42f9f 294 Gene3D G3DSA:3.30.572.10 1 287 3.7E-110 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 JANET_102 e764f56eae62b425ad4233aa72364020 746 SUPERFAMILY SSF54001 603 743 2.45E-20 T 30-10-2018 IPR038765 Papain-like cysteine peptidase superfamily JANET_102 e764f56eae62b425ad4233aa72364020 746 Pfam PF00877 NlpC/P60 family 616 741 2.9E-17 T 30-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain JANET_102 e764f56eae62b425ad4233aa72364020 746 Gene3D G3DSA:3.90.1720.10 598 745 1.9E-23 T 30-10-2018 JANET_138 7693779cdb0cf136e5d0a1a33a8c3f83 773 Gene3D G3DSA:3.20.70.20 221 757 1.1E-151 T 30-10-2018 JANET_138 7693779cdb0cf136e5d0a1a33a8c3f83 773 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 156 233 1.3E-14 T 30-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 JANET_138 7693779cdb0cf136e5d0a1a33a8c3f83 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 515 538 7.8E-25 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 JANET_138 7693779cdb0cf136e5d0a1a33a8c3f83 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 553 575 7.8E-25 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 JANET_138 7693779cdb0cf136e5d0a1a33a8c3f83 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 641 668 7.8E-25 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 JANET_138 7693779cdb0cf136e5d0a1a33a8c3f83 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 461 472 7.8E-25 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 JANET_138 7693779cdb0cf136e5d0a1a33a8c3f83 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 311 330 7.8E-25 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 JANET_138 7693779cdb0cf136e5d0a1a33a8c3f83 773 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 160 759 1.5E-126 T 30-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 JANET_138 7693779cdb0cf136e5d0a1a33a8c3f83 773 Gene3D G3DSA:1.10.1650.20 354 423 1.1E-151 T 30-10-2018 JANET_138 7693779cdb0cf136e5d0a1a33a8c3f83 773 SUPERFAMILY SSF51998 235 761 1.43E-122 T 30-10-2018 JANET_138 7693779cdb0cf136e5d0a1a33a8c3f83 773 Pfam PF02867 Ribonucleotide reductase, barrel domain 236 756 3.5E-105 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 JANET_138 7693779cdb0cf136e5d0a1a33a8c3f83 773 SUPERFAMILY SSF48168 44 232 4.45E-39 T 30-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 JANET_130 1408f1a463d111f8d574b95638e16ee2 360 Gene3D G3DSA:3.40.1360.10 230 346 8.3E-8 T 30-10-2018 JANET_130 1408f1a463d111f8d574b95638e16ee2 360 SMART SM00400 25 76 0.0046 T 30-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 JANET_130 1408f1a463d111f8d574b95638e16ee2 360 SUPERFAMILY SSF56731 141 344 5.49E-18 T 30-10-2018 JANET_130 1408f1a463d111f8d574b95638e16ee2 360 Gene3D G3DSA:3.90.580.10 2 83 7.1E-11 T 30-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 JANET_130 1408f1a463d111f8d574b95638e16ee2 360 Pfam PF01807 CHC2 zinc finger 23 73 5.5E-6 T 30-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 JANET_130 1408f1a463d111f8d574b95638e16ee2 360 SUPERFAMILY SSF57783 15 75 5.78E-14 T 30-10-2018 JANET_18 0f1cb22926b2bc48f3baa7e83ead4dfc 395 Pfam PF01139 tRNA-splicing ligase RtcB 38 111 1.6E-12 T 30-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 JANET_18 0f1cb22926b2bc48f3baa7e83ead4dfc 395 Pfam PF01139 tRNA-splicing ligase RtcB 131 393 6.9E-54 T 30-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 JANET_18 0f1cb22926b2bc48f3baa7e83ead4dfc 395 SUPERFAMILY SSF103365 3 394 9.68E-106 T 30-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 JANET_18 0f1cb22926b2bc48f3baa7e83ead4dfc 395 Gene3D G3DSA:3.90.1860.10 5 394 1.0E-70 T 30-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 JANET_118 5bd7fb18805dae42458181038906175c 496 Pfam PF03796 DnaB-like helicase C terminal domain 175 364 2.3E-17 T 30-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 JANET_118 5bd7fb18805dae42458181038906175c 496 SUPERFAMILY SSF52540 174 416 7.5E-25 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase JANET_118 5bd7fb18805dae42458181038906175c 496 Gene3D G3DSA:3.40.50.300 152 429 4.8E-41 T 30-10-2018 JANET_186 100b064c0ea8ff33d2856978d646cc07 399 SUPERFAMILY SSF52540 30 284 3.7E-26 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase JANET_186 100b064c0ea8ff33d2856978d646cc07 399 PRINTS PR00142 RecA protein signature 260 289 1.4E-8 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 JANET_186 100b064c0ea8ff33d2856978d646cc07 399 PRINTS PR00142 RecA protein signature 92 121 1.4E-8 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 JANET_186 100b064c0ea8ff33d2856978d646cc07 399 PRINTS PR00142 RecA protein signature 223 251 1.4E-8 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 JANET_186 100b064c0ea8ff33d2856978d646cc07 399 Gene3D G3DSA:3.40.50.300 33 349 4.2E-65 T 30-10-2018 JANET_186 100b064c0ea8ff33d2856978d646cc07 399 Pfam PF00154 recA bacterial DNA recombination protein 46 284 8.4E-34 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 JANET_112 ea5c294991dc38042fc0cd2d254314d2 834 Gene3D G3DSA:2.60.120.260 261 423 4.9E-8 T 30-10-2018 IPR008979 Galactose-binding-like domain superfamily JANET_112 ea5c294991dc38042fc0cd2d254314d2 834 Gene3D G3DSA:2.60.120.260 701 801 3.0E-5 T 30-10-2018 IPR008979 Galactose-binding-like domain superfamily JANET_215 6127c8fc07ee59a4e6feb81388ed997f 305 PRINTS PR00046 Major sigma-70 factor signature 210 225 1.1E-6 T 30-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 JANET_215 6127c8fc07ee59a4e6feb81388ed997f 305 PRINTS PR00046 Major sigma-70 factor signature 52 65 1.1E-6 T 30-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 JANET_215 6127c8fc07ee59a4e6feb81388ed997f 305 PRINTS PR00046 Major sigma-70 factor signature 193 205 1.1E-6 T 30-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 JANET_215 6127c8fc07ee59a4e6feb81388ed997f 305 PRINTS PR00046 Major sigma-70 factor signature 225 236 1.1E-6 T 30-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 JANET_215 6127c8fc07ee59a4e6feb81388ed997f 305 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 239 1.3E-22 T 30-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 JANET_215 6127c8fc07ee59a4e6feb81388ed997f 305 SUPERFAMILY SSF88659 174 243 9.91E-11 T 30-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like JANET_215 6127c8fc07ee59a4e6feb81388ed997f 305 Pfam PF04542 Sigma-70 region 2 28 96 2.5E-9 T 30-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 JANET_215 6127c8fc07ee59a4e6feb81388ed997f 305 Gene3D G3DSA:1.20.120.1810 2 96 3.9E-11 T 30-10-2018 JANET_215 6127c8fc07ee59a4e6feb81388ed997f 305 Gene3D G3DSA:1.20.140.160 97 243 6.8E-13 T 30-10-2018 JANET_215 6127c8fc07ee59a4e6feb81388ed997f 305 Pfam PF04545 Sigma-70, region 4 191 238 8.2E-6 T 30-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 JANET_215 6127c8fc07ee59a4e6feb81388ed997f 305 SUPERFAMILY SSF88946 11 95 9.55E-18 T 30-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 JANET_98 ca08c31f564aeee49dfb474fe4f521d4 220 Gene3D G3DSA:2.40.40.10 70 201 4.8E-7 T 30-10-2018 IPR036908 RlpA-like domain superfamily JANET_98 ca08c31f564aeee49dfb474fe4f521d4 220 Pfam PF06725 3D domain 159 220 8.9E-21 T 30-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 JANET_98 ca08c31f564aeee49dfb474fe4f521d4 220 SUPERFAMILY SSF50685 151 200 6.98E-9 T 30-10-2018 IPR036908 RlpA-like domain superfamily JANET_195 d7d5b68c9e321f69f44af8b71fbe50f4 428 Gene3D G3DSA:3.60.21.10 164 395 1.9E-8 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like JANET_195 d7d5b68c9e321f69f44af8b71fbe50f4 428 SUPERFAMILY SSF56300 165 385 5.27E-12 T 30-10-2018 JANET_115 21b3f561febc9b0161eea93406c11ff7 590 Pfam PF04851 Type III restriction enzyme, res subunit 237 367 6.8E-8 T 30-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 JANET_115 21b3f561febc9b0161eea93406c11ff7 590 Pfam PF04851 Type III restriction enzyme, res subunit 117 223 7.3E-11 T 30-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 JANET_115 21b3f561febc9b0161eea93406c11ff7 590 Gene3D G3DSA:3.40.50.300 238 396 4.8E-10 T 30-10-2018 JANET_115 21b3f561febc9b0161eea93406c11ff7 590 Gene3D G3DSA:3.40.50.300 100 237 6.8E-13 T 30-10-2018 JANET_115 21b3f561febc9b0161eea93406c11ff7 590 Gene3D G3DSA:3.40.50.300 405 589 2.0E-36 T 30-10-2018 JANET_115 21b3f561febc9b0161eea93406c11ff7 590 Pfam PF00271 Helicase conserved C-terminal domain 449 545 5.3E-14 T 30-10-2018 IPR001650 Helicase, C-terminal JANET_115 21b3f561febc9b0161eea93406c11ff7 590 SUPERFAMILY SSF52540 22 384 1.24E-23 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase JANET_115 21b3f561febc9b0161eea93406c11ff7 590 SUPERFAMILY SSF52540 327 563 2.37E-28 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase JANET_115 21b3f561febc9b0161eea93406c11ff7 590 SMART SM00487 115 397 2.7E-7 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain JANET_115 21b3f561febc9b0161eea93406c11ff7 590 SMART SM00490 465 546 2.7E-17 T 30-10-2018 IPR001650 Helicase, C-terminal JANET_81 03c7ec68ab68d885845ed5cad5a1c2bb 278 Gene3D G3DSA:2.160.20.10 2 270 1.3E-6 T 30-10-2018 IPR012334 Pectin lyase fold JANET_81 03c7ec68ab68d885845ed5cad5a1c2bb 278 SUPERFAMILY SSF51126 3 204 4.71E-8 T 30-10-2018 IPR011050 Pectin lyase fold/virulence factor JANET_145 bfb9dfd09c8a4eacf03e31197b66730b 374 Pfam PF00268 Ribonucleotide reductase, small chain 45 327 1.5E-44 T 30-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 JANET_145 bfb9dfd09c8a4eacf03e31197b66730b 374 Gene3D G3DSA:1.10.620.20 30 338 8.5E-68 T 30-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 JANET_145 bfb9dfd09c8a4eacf03e31197b66730b 374 SUPERFAMILY SSF47240 33 338 2.55E-55 T 30-10-2018 IPR009078 Ferritin-like superfamily JANET_48 02b513598f6c0c894ad8318b6d24880b 200 Pfam PF13238 AAA domain 4 146 1.5E-8 T 30-10-2018 JANET_48 02b513598f6c0c894ad8318b6d24880b 200 SUPERFAMILY SSF52540 1 187 2.44E-8 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase JANET_48 02b513598f6c0c894ad8318b6d24880b 200 Gene3D G3DSA:3.40.50.300 1 198 7.2E-27 T 30-10-2018 JANET_137 1b642acf4a21660dac8a30a43cead5d3 187 ProDom PD927567 D14 PHAGE GP54 SPO1 GENE ORF78 ORF063 ORF064 8 138 6.0E-20 T 30-10-2018 JANET_111 02f4783ef7190cf280a857d4f4d8aca2 348 Pfam PF04865 Baseplate J-like protein 65 306 8.8E-31 T 30-10-2018 IPR006949 Baseplate protein J-like JANET_113 6de4a5eb807ba4438ff8fbe2880f43ca 1180 Pfam PF16075 Domain of unknown function (DUF4815) 11 628 9.3E-150 T 30-10-2018 IPR032096 Domain of unknown function DUF4815 JANET_72 95e7692fdd1a289839ce2562e8cb1b1d 82 Gene3D G3DSA:1.10.260.40 2 82 3.6E-15 T 30-10-2018 JANET_72 95e7692fdd1a289839ce2562e8cb1b1d 82 SMART SM00530 11 66 1.0E-8 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 JANET_72 95e7692fdd1a289839ce2562e8cb1b1d 82 Pfam PF01381 Helix-turn-helix 12 62 2.0E-9 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 JANET_72 95e7692fdd1a289839ce2562e8cb1b1d 82 SUPERFAMILY SSF47413 4 72 1.72E-14 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 JANET_123 513d0764dbbbabb87aaae2017504e427 365 Gene3D G3DSA:3.60.21.10 4 266 1.0E-30 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like JANET_123 513d0764dbbbabb87aaae2017504e427 365 Pfam PF00149 Calcineurin-like phosphoesterase 4 217 1.7E-7 T 30-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 JANET_123 513d0764dbbbabb87aaae2017504e427 365 SUPERFAMILY SSF56300 5 287 5.32E-24 T 30-10-2018 JANET_116 5e5eaaa2ad06d47f79124c29a5a0839e 278 Gene3D G3DSA:1.10.10.10 50 144 7.1E-8 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily JANET_256 95e5eb27eb813c113c0bdf09667f81af 308 SUPERFAMILY SSF56091 23 168 3.24E-20 T 30-10-2018 JANET_256 95e5eb27eb813c113c0bdf09667f81af 308 Gene3D G3DSA:3.30.470.30 10 188 2.0E-18 T 30-10-2018 JANET_256 95e5eb27eb813c113c0bdf09667f81af 308 Pfam PF09414 RNA ligase 29 189 5.8E-22 T 30-10-2018 IPR021122 RNA ligase domain, REL/Rln2 JANET_61 2d19fb002a004026ce7e0771f59877a3 364 Gene3D G3DSA:3.20.20.80 12 209 5.3E-60 T 30-10-2018 JANET_61 2d19fb002a004026ce7e0771f59877a3 364 SUPERFAMILY SSF51445 13 198 1.47E-36 T 30-10-2018 IPR017853 Glycoside hydrolase superfamily JANET_61 2d19fb002a004026ce7e0771f59877a3 364 Pfam PF12123 N-acetylmuramoyl-l-alanine amidase 252 284 8.4E-9 T 30-10-2018 IPR021976 N-acetylmuramoyl-l-alanine amidase MetaCyc: PWY-7883 JANET_61 2d19fb002a004026ce7e0771f59877a3 364 Pfam PF01183 Glycosyl hydrolases family 25 15 186 4.3E-17 T 30-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 JANET_148 505cd47cfcb84b9610ff7a46d8849f5d 89 SUPERFAMILY SSF52833 9 64 5.71E-7 T 30-10-2018 IPR036249 Thioredoxin-like superfamily JANET_125 911fda5e9b29185c33d33b77a467c31a 195 Gene3D G3DSA:3.30.420.10 1 190 5.0E-16 T 30-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 JANET_125 911fda5e9b29185c33d33b77a467c31a 195 Pfam PF16473 3' exoribonuclease, RNase T-like 8 185 9.2E-31 T 30-10-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain JANET_125 911fda5e9b29185c33d33b77a467c31a 195 SUPERFAMILY SSF53098 9 189 1.01E-15 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily JANET_86 345ba7a1883a97eb0063884a4a27e5b2 270 Pfam PF04586 Caudovirus prohead serine protease 51 177 3.3E-5 T 30-10-2018 IPR006433 Prohead protease JANET_84 6b42bc1550fcab6c03461b2c759e4a9c 557 Pfam PF04860 Phage portal protein 163 461 2.0E-18 T 30-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein JANET_132 9279925969179d9daf332e867b9c813d 300 SUPERFAMILY SSF51283 45 138 3.53E-11 T 30-10-2018 IPR036157 dUTPase-like superfamily JANET_132 9279925969179d9daf332e867b9c813d 300 SUPERFAMILY SSF51283 254 299 1.15E-9 T 30-10-2018 IPR036157 dUTPase-like superfamily JANET_132 9279925969179d9daf332e867b9c813d 300 Pfam PF00692 dUTPase 256 297 1.0E-4 T 30-10-2018 IPR029054 dUTPase-like JANET_273 30318d0bb3d9a119aa1240bf10feaa91 123 SUPERFAMILY SSF47413 34 81 2.0E-6 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 JANET_273 30318d0bb3d9a119aa1240bf10feaa91 123 Gene3D G3DSA:1.10.260.40 17 82 3.8E-9 T 30-10-2018 JANET_154 0faebf48456d97e37942bcfd326e4869 105 SUPERFAMILY SSF47729 7 92 2.5E-11 T 30-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 JANET_154 0faebf48456d97e37942bcfd326e4869 105 Pfam PF00216 Bacterial DNA-binding protein 8 92 3.9E-11 T 30-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 JANET_154 0faebf48456d97e37942bcfd326e4869 105 Gene3D G3DSA:4.10.520.10 6 100 1.1E-6 T 30-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 JANET_101 a96e8c8d1010496f5ac02c3cbefd82bc 1291 SMART SM00047 1112 1251 8.0E-6 T 30-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 JANET_101 a96e8c8d1010496f5ac02c3cbefd82bc 1291 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 1126 1235 1.6E-13 T 30-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 JANET_101 a96e8c8d1010496f5ac02c3cbefd82bc 1291 Gene3D G3DSA:1.10.530.10 1120 1237 6.5E-14 T 30-10-2018 JANET_211 767184f219c234445d8acd8f2fc8cf4e 196 Gene3D G3DSA:1.10.10.60 35 82 1.6E-6 T 30-10-2018 JANET_127 1b009dd2117ec594b5666eab8d086618 628 SUPERFAMILY SSF75712 280 362 6.54E-7 T 30-10-2018 JANET_127 1b009dd2117ec594b5666eab8d086618 628 Pfam PF13476 AAA domain 5 211 3.0E-15 T 30-10-2018 IPR038729 Rad50/SbcC-type AAA domain JANET_127 1b009dd2117ec594b5666eab8d086618 628 SUPERFAMILY SSF52540 1 620 3.3E-27 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase JANET_127 1b009dd2117ec594b5666eab8d086618 628 Gene3D G3DSA:3.40.50.300 1 371 6.4E-30 T 30-10-2018 JANET_127 1b009dd2117ec594b5666eab8d086618 628 Gene3D G3DSA:3.40.50.300 372 625 1.6E-25 T 30-10-2018 JANET_63 c3c62d95d7f2705a038720afa1ae7d6d 598 Gene3D G3DSA:3.40.50.300 54 230 3.9E-11 T 30-10-2018 JANET_63 c3c62d95d7f2705a038720afa1ae7d6d 598 Pfam PF05876 Phage terminase large subunit (GpA) 66 426 8.9E-25 T 30-10-2018 IPR008866 Bacteriophage lambda, GpA JANET_190 d42f44d044717b129820529f1aba6d0b 100 Pfam PF04688 SPP1 phage holin 20 89 4.8E-14 T 30-10-2018 IPR006479 Holin JANET_156 b547ee65f9a9c6428c5e391a7b9a4db3 68 Pfam PF13783 Domain of unknown function (DUF4177) 4 37 4.4E-6 T 30-10-2018 IPR025234 Protein of unknown function DUF4177 JANET_205 d758b6dfd35e92a3cdf33ced9e341cc4 247 SUPERFAMILY SSF54171 174 216 2.03E-6 T 30-10-2018 IPR016177 DNA-binding domain superfamily GO:0003677