OTK52_72 95e7692fdd1a289839ce2562e8cb1b1d 82 Gene3D G3DSA:1.10.260.40 2 82 3.6E-15 T 30-10-2018 OTK52_72 95e7692fdd1a289839ce2562e8cb1b1d 82 SMART SM00530 11 66 1.0E-8 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 OTK52_72 95e7692fdd1a289839ce2562e8cb1b1d 82 Pfam PF01381 Helix-turn-helix 12 62 2.0E-9 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 OTK52_72 95e7692fdd1a289839ce2562e8cb1b1d 82 SUPERFAMILY SSF47413 4 72 1.72E-14 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 OTK52_61 dee63bfa6a6fc8badb7ea9458fd77cfc 364 Pfam PF12123 N-acetylmuramoyl-l-alanine amidase 252 284 1.9E-8 T 30-10-2018 IPR021976 N-acetylmuramoyl-l-alanine amidase MetaCyc: PWY-7883 OTK52_61 dee63bfa6a6fc8badb7ea9458fd77cfc 364 Pfam PF01183 Glycosyl hydrolases family 25 15 186 3.8E-17 T 30-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 OTK52_61 dee63bfa6a6fc8badb7ea9458fd77cfc 364 SUPERFAMILY SSF51445 14 198 3.58E-37 T 30-10-2018 IPR017853 Glycoside hydrolase superfamily OTK52_61 dee63bfa6a6fc8badb7ea9458fd77cfc 364 Gene3D G3DSA:3.20.20.80 12 209 4.0E-60 T 30-10-2018 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 156 233 1.3E-14 T 30-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 515 538 5.0E-26 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 553 575 5.0E-26 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 581 604 5.0E-26 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 461 472 5.0E-26 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 311 330 5.0E-26 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 641 668 5.0E-26 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 Gene3D G3DSA:3.20.70.20 221 757 1.8E-152 T 30-10-2018 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 160 759 6.7E-127 T 30-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 Gene3D G3DSA:1.10.1650.20 354 423 1.8E-152 T 30-10-2018 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 SUPERFAMILY SSF51998 235 761 5.49E-123 T 30-10-2018 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 Pfam PF02867 Ribonucleotide reductase, barrel domain 236 756 1.1E-105 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 OTK52_134 5fe6334fb907d3b2d9da612071194098 773 SUPERFAMILY SSF48168 44 232 4.45E-39 T 30-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 OTK52_128 247bc95c1a6699987935e39d68cace67 300 SUPERFAMILY SSF51283 254 299 7.59E-10 T 30-10-2018 IPR036157 dUTPase-like superfamily OTK52_128 247bc95c1a6699987935e39d68cace67 300 SUPERFAMILY SSF51283 46 138 5.23E-12 T 30-10-2018 IPR036157 dUTPase-like superfamily OTK52_128 247bc95c1a6699987935e39d68cace67 300 Pfam PF00692 dUTPase 256 297 1.0E-4 T 30-10-2018 IPR029054 dUTPase-like OTK52_99 8fe3ab787dbe4115c3dbaa59dadbba21 1293 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 1129 1237 4.5E-13 T 30-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 OTK52_99 8fe3ab787dbe4115c3dbaa59dadbba21 1293 SMART SM00047 1114 1253 7.1E-6 T 30-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 OTK52_99 8fe3ab787dbe4115c3dbaa59dadbba21 1293 Gene3D G3DSA:1.10.530.10 1122 1239 8.3E-14 T 30-10-2018 OTK52_143 0f90600a51fa0d423ee65390e73caf73 153 Pfam PF00258 Flavodoxin 45 121 1.9E-6 T 30-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 OTK52_143 0f90600a51fa0d423ee65390e73caf73 153 SUPERFAMILY SSF52218 9 125 4.19E-11 T 30-10-2018 IPR029039 Flavoprotein-like superfamily OTK52_143 0f90600a51fa0d423ee65390e73caf73 153 Gene3D G3DSA:3.40.50.360 9 151 3.8E-10 T 30-10-2018 IPR029039 Flavoprotein-like superfamily OTK52_215 623c352c884643086ad241a1a8c8cd4c 305 Gene3D G3DSA:1.20.120.1810 1 98 4.7E-9 T 30-10-2018 OTK52_215 623c352c884643086ad241a1a8c8cd4c 305 Pfam PF04542 Sigma-70 region 2 28 97 5.0E-9 T 30-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 OTK52_215 623c352c884643086ad241a1a8c8cd4c 305 Pfam PF04545 Sigma-70, region 4 193 240 6.0E-6 T 30-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 OTK52_215 623c352c884643086ad241a1a8c8cd4c 305 Gene3D G3DSA:1.20.140.160 103 244 7.3E-14 T 30-10-2018 OTK52_215 623c352c884643086ad241a1a8c8cd4c 305 SUPERFAMILY SSF88659 183 242 1.12E-10 T 30-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like OTK52_215 623c352c884643086ad241a1a8c8cd4c 305 SUPERFAMILY SSF88946 15 97 1.07E-14 T 30-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 OTK52_215 623c352c884643086ad241a1a8c8cd4c 305 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 240 9.4E-25 T 30-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 OTK52_50 26607e9bd176e1c9ff6c08ea7f95e9ca 294 Hamap MF_00008 Thymidylate synthase [thyA]. 5 287 33.378 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 OTK52_50 26607e9bd176e1c9ff6c08ea7f95e9ca 294 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 7 287 3.5E-102 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 OTK52_50 26607e9bd176e1c9ff6c08ea7f95e9ca 294 PRINTS PR00108 Thymidylate synthase family signature 220 237 1.8E-34 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 OTK52_50 26607e9bd176e1c9ff6c08ea7f95e9ca 294 PRINTS PR00108 Thymidylate synthase family signature 137 156 1.8E-34 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 OTK52_50 26607e9bd176e1c9ff6c08ea7f95e9ca 294 PRINTS PR00108 Thymidylate synthase family signature 163 178 1.8E-34 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 OTK52_50 26607e9bd176e1c9ff6c08ea7f95e9ca 294 PRINTS PR00108 Thymidylate synthase family signature 182 208 1.8E-34 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 OTK52_50 26607e9bd176e1c9ff6c08ea7f95e9ca 294 PRINTS PR00108 Thymidylate synthase family signature 46 67 1.8E-34 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 OTK52_50 26607e9bd176e1c9ff6c08ea7f95e9ca 294 Gene3D G3DSA:3.30.572.10 1 287 5.8E-111 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 OTK52_50 26607e9bd176e1c9ff6c08ea7f95e9ca 294 Pfam PF00303 Thymidylate synthase 7 287 6.3E-97 T 30-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 OTK52_50 26607e9bd176e1c9ff6c08ea7f95e9ca 294 SUPERFAMILY SSF55831 2 287 2.88E-107 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 OTK52_124 5b24998ec072fc6cdf88ddfd32f0129a 632 Pfam PF13476 AAA domain 5 211 4.2E-15 T 30-10-2018 IPR038729 Rad50/SbcC-type AAA domain OTK52_124 5b24998ec072fc6cdf88ddfd32f0129a 632 Gene3D G3DSA:3.40.50.300 349 632 1.0E-18 T 30-10-2018 OTK52_124 5b24998ec072fc6cdf88ddfd32f0129a 632 SUPERFAMILY SSF75712 280 362 1.7E-6 T 30-10-2018 OTK52_124 5b24998ec072fc6cdf88ddfd32f0129a 632 Gene3D G3DSA:3.40.50.300 1 250 2.5E-25 T 30-10-2018 OTK52_124 5b24998ec072fc6cdf88ddfd32f0129a 632 SUPERFAMILY SSF52540 1 622 1.29E-26 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase OTK52_54 a7c8992014ff16b5b36daaff1a312861 465 Pfam PF14284 PcfJ-like protein 314 451 3.7E-29 T 30-10-2018 IPR025586 PcfJ-like protein OTK52_83 48146256537bfcbbc95ba24f773bb348 557 Pfam PF04860 Phage portal protein 163 461 3.9E-19 T 30-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein OTK52_277 7248ae5c1807b5e660573fe40d9f32dd 136 Gene3D G3DSA:1.10.260.40 30 95 4.8E-9 T 30-10-2018 OTK52_277 7248ae5c1807b5e660573fe40d9f32dd 136 SUPERFAMILY SSF47413 48 94 2.53E-6 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 OTK52_152 51af789502f4c8164dae829165991516 114 Gene3D G3DSA:4.10.520.10 6 104 1.4E-6 T 30-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 OTK52_152 51af789502f4c8164dae829165991516 114 Pfam PF00216 Bacterial DNA-binding protein 8 92 4.8E-11 T 30-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 OTK52_152 51af789502f4c8164dae829165991516 114 SUPERFAMILY SSF47729 7 92 3.09E-11 T 30-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 OTK52_113 8f42c5534f7dea483ee8465b14e4e0c4 590 Gene3D G3DSA:3.40.50.300 238 396 3.8E-10 T 30-10-2018 OTK52_113 8f42c5534f7dea483ee8465b14e4e0c4 590 Gene3D G3DSA:3.40.50.300 100 237 1.0E-12 T 30-10-2018 OTK52_113 8f42c5534f7dea483ee8465b14e4e0c4 590 SUPERFAMILY SSF52540 327 563 2.18E-28 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase OTK52_113 8f42c5534f7dea483ee8465b14e4e0c4 590 Gene3D G3DSA:3.40.50.300 405 589 1.4E-36 T 30-10-2018 OTK52_113 8f42c5534f7dea483ee8465b14e4e0c4 590 SUPERFAMILY SSF52540 22 384 2.42E-23 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase OTK52_113 8f42c5534f7dea483ee8465b14e4e0c4 590 SMART SM00490 465 546 2.2E-17 T 30-10-2018 IPR001650 Helicase, C-terminal OTK52_113 8f42c5534f7dea483ee8465b14e4e0c4 590 Pfam PF04851 Type III restriction enzyme, res subunit 117 223 2.8E-10 T 30-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 OTK52_113 8f42c5534f7dea483ee8465b14e4e0c4 590 Pfam PF04851 Type III restriction enzyme, res subunit 237 367 6.3E-8 T 30-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 OTK52_113 8f42c5534f7dea483ee8465b14e4e0c4 590 Pfam PF00271 Helicase conserved C-terminal domain 449 545 2.7E-14 T 30-10-2018 IPR001650 Helicase, C-terminal OTK52_113 8f42c5534f7dea483ee8465b14e4e0c4 590 SMART SM00487 115 397 1.0E-6 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain OTK52_43 4a027e33edfad50cfffbb91bc647e677 106 ProDom PD029230 GPA 5'REGION GP83 ORF83 GENE GP45 BACTERIOPHAGE SIMILAR ORF4 1 88 0.01 T 30-10-2018 IPR020284 Protein of unknown function CP83 OTK52_236 c746e52352510ae1015a11ee7cec326f 752 SMART SM00382 434 600 7.9E-6 T 30-10-2018 IPR003593 AAA+ ATPase domain OTK52_236 c746e52352510ae1015a11ee7cec326f 752 SUPERFAMILY SSF52540 403 649 6.05E-29 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase OTK52_236 c746e52352510ae1015a11ee7cec326f 752 Gene3D G3DSA:3.40.50.300 394 661 4.4E-78 T 30-10-2018 OTK52_236 c746e52352510ae1015a11ee7cec326f 752 Pfam PF01580 FtsK/SpoIIIE family 397 549 9.0E-38 T 30-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 Pfam PF01612 3'-5' exonuclease 199 347 5.7E-13 T 30-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 Gene3D G3DSA:3.40.470.10 16 178 4.0E-14 T 30-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 Gene3D G3DSA:3.30.420.10 188 399 2.9E-28 T 30-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 Gene3D G3DSA:3.30.70.370 692 943 2.8E-65 T 30-10-2018 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 SMART SM00474 189 389 7.6E-4 T 30-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 SMART SM00482 723 927 7.5E-37 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 735 758 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 910 923 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 880 896 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 765 778 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 789 814 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 826 837 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 PRINTS PR00868 DNA-polymerase family A (pol I) signature 683 705 5.5E-28 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 SUPERFAMILY SSF56672 491 973 2.56E-95 T 30-10-2018 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 Pfam PF00476 DNA polymerase family A 565 970 4.2E-70 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 Gene3D G3DSA:1.10.150.20 744 887 2.8E-65 T 30-10-2018 OTK52_164 4e2c4a08a64ab14c3844224da106f20d 1032 SUPERFAMILY SSF53098 202 331 1.48E-19 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily OTK52_80 1397fc2bb7b04a875076cc1a172bdd4f 278 SUPERFAMILY SSF51126 3 204 8.57E-8 T 30-10-2018 IPR011050 Pectin lyase fold/virulence factor OTK52_80 1397fc2bb7b04a875076cc1a172bdd4f 278 Gene3D G3DSA:2.160.20.10 2 270 2.6E-6 T 30-10-2018 IPR012334 Pectin lyase fold OTK52_108 b4ffecbb25a22ddfe0535e7c440df4bf 239 Gene3D G3DSA:3.10.350.10 8 65 6.7E-6 T 30-10-2018 IPR036779 LysM domain superfamily OTK52_108 b4ffecbb25a22ddfe0535e7c440df4bf 239 Pfam PF01476 LysM domain 9 43 0.0015 T 30-10-2018 IPR018392 LysM domain OTK52_108 b4ffecbb25a22ddfe0535e7c440df4bf 239 Gene3D G3DSA:3.10.450.40 119 232 1.0E-9 T 30-10-2018 OTK52_108 b4ffecbb25a22ddfe0535e7c440df4bf 239 SUPERFAMILY SSF160719 128 224 2.62E-15 T 30-10-2018 OTK52_184 753cde283320bd0c26c4c26126da6196 399 SUPERFAMILY SSF52540 30 284 3.7E-26 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase OTK52_184 753cde283320bd0c26c4c26126da6196 399 PRINTS PR00142 RecA protein signature 260 289 1.4E-8 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 OTK52_184 753cde283320bd0c26c4c26126da6196 399 PRINTS PR00142 RecA protein signature 92 121 1.4E-8 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 OTK52_184 753cde283320bd0c26c4c26126da6196 399 PRINTS PR00142 RecA protein signature 223 251 1.4E-8 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 OTK52_184 753cde283320bd0c26c4c26126da6196 399 Pfam PF00154 recA bacterial DNA recombination protein 46 284 8.4E-34 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 OTK52_184 753cde283320bd0c26c4c26126da6196 399 Gene3D G3DSA:3.40.50.300 33 349 4.2E-65 T 30-10-2018 OTK52_121 f8e311f983ae78ae117ba8251aa427c6 365 Pfam PF00149 Calcineurin-like phosphoesterase 4 217 1.8E-7 T 30-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 OTK52_121 f8e311f983ae78ae117ba8251aa427c6 365 SUPERFAMILY SSF56300 5 287 4.29E-24 T 30-10-2018 OTK52_121 f8e311f983ae78ae117ba8251aa427c6 365 Gene3D G3DSA:3.60.21.10 4 266 1.0E-30 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like OTK52_116 5c14720f303789257377369321f0319a 496 Pfam PF03796 DnaB-like helicase C terminal domain 175 364 2.3E-17 T 30-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 OTK52_116 5c14720f303789257377369321f0319a 496 SUPERFAMILY SSF52540 174 416 7.5E-25 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase OTK52_116 5c14720f303789257377369321f0319a 496 Gene3D G3DSA:3.40.50.300 152 429 4.8E-41 T 30-10-2018 OTK52_209 bdb515c92f2959baa8ab53d83319d864 192 Gene3D G3DSA:1.10.10.60 35 82 1.6E-6 T 30-10-2018 OTK52_115 3314c38887536d9e7843f4ab2ceccbcb 594 Gene3D G3DSA:1.10.10.10 26 93 7.5E-6 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily OTK52_115 3314c38887536d9e7843f4ab2ceccbcb 594 Pfam PF08279 HTH domain 48 83 3.4E-5 T 30-10-2018 IPR013196 Helix-turn-helix, type 11 OTK52_115 3314c38887536d9e7843f4ab2ceccbcb 594 SUPERFAMILY SSF46785 48 90 1.08E-5 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily OTK52_193 9a72c103ae5950e6f6f4c4cf379933f8 428 SUPERFAMILY SSF56300 165 385 2.6E-12 T 30-10-2018 OTK52_193 9a72c103ae5950e6f6f4c4cf379933f8 428 Gene3D G3DSA:3.60.21.10 164 395 1.0E-8 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like OTK52_224 2d3b56bccc18fdcec7f43995af5a2ea3 241 Gene3D G3DSA:3.60.15.10 5 240 6.7E-27 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like OTK52_224 2d3b56bccc18fdcec7f43995af5a2ea3 241 SUPERFAMILY SSF56281 4 229 7.47E-26 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like OTK52_224 2d3b56bccc18fdcec7f43995af5a2ea3 241 SMART SM00849 18 220 4.5E-9 T 30-10-2018 IPR001279 Metallo-beta-lactamase OTK52_224 2d3b56bccc18fdcec7f43995af5a2ea3 241 Pfam PF12706 Beta-lactamase superfamily domain 31 219 1.7E-16 T 30-10-2018 IPR001279 Metallo-beta-lactamase OTK52_259 b60d6092c21a69dae15cce6bf1cf7741 308 Pfam PF09414 RNA ligase 29 189 1.0E-21 T 30-10-2018 IPR021122 RNA ligase domain, REL/Rln2 OTK52_259 b60d6092c21a69dae15cce6bf1cf7741 308 Gene3D G3DSA:3.30.470.30 10 188 1.2E-18 T 30-10-2018 OTK52_259 b60d6092c21a69dae15cce6bf1cf7741 308 SUPERFAMILY SSF56091 23 168 1.37E-19 T 30-10-2018 OTK52_44 7d1552ffac0fec47ef8f1b33eb43fccf 166 PRINTS PR00070 Dihydrofolate reductase signature 94 108 1.8E-5 T 30-10-2018 OTK52_44 7d1552ffac0fec47ef8f1b33eb43fccf 166 PRINTS PR00070 Dihydrofolate reductase signature 28 36 1.8E-5 T 30-10-2018 OTK52_44 7d1552ffac0fec47ef8f1b33eb43fccf 166 PRINTS PR00070 Dihydrofolate reductase signature 41 52 1.8E-5 T 30-10-2018 OTK52_44 7d1552ffac0fec47ef8f1b33eb43fccf 166 Gene3D G3DSA:3.40.430.10 1 166 2.8E-46 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 OTK52_44 7d1552ffac0fec47ef8f1b33eb43fccf 166 Pfam PF00186 Dihydrofolate reductase 3 163 1.6E-45 T 30-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 OTK52_44 7d1552ffac0fec47ef8f1b33eb43fccf 166 SUPERFAMILY SSF53597 1 160 3.02E-44 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 OTK52_229 c9dfeee47940db9ce4a45a51b4621306 357 SUPERFAMILY SSF53067 11 175 6.47E-15 T 30-10-2018 OTK52_229 c9dfeee47940db9ce4a45a51b4621306 357 SUPERFAMILY SSF53067 187 333 5.61E-11 T 30-10-2018 OTK52_229 c9dfeee47940db9ce4a45a51b4621306 357 Gene3D G3DSA:3.30.420.40 181 317 7.1E-32 T 30-10-2018 OTK52_229 c9dfeee47940db9ce4a45a51b4621306 357 Gene3D G3DSA:3.30.420.40 11 333 7.1E-32 T 30-10-2018 OTK52_110 c7c619bd5868333040e011584c03e8e2 670 Pfam PF02018 Carbohydrate binding domain 267 401 8.7E-6 T 30-10-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 OTK52_110 c7c619bd5868333040e011584c03e8e2 670 Gene3D G3DSA:2.60.120.260 262 424 1.3E-9 T 30-10-2018 IPR008979 Galactose-binding-like domain superfamily OTK52_109 d2be8a4bff7be647e9c2df03375053b2 348 Pfam PF04865 Baseplate J-like protein 65 306 1.2E-30 T 30-10-2018 IPR006949 Baseplate protein J-like OTK52_48 ce313ea0dc6f6a6814ba7e4592630b39 200 SUPERFAMILY SSF52540 1 187 2.77E-8 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase OTK52_48 ce313ea0dc6f6a6814ba7e4592630b39 200 Gene3D G3DSA:3.40.50.300 1 198 2.5E-26 T 30-10-2018 OTK52_85 dd5db644bdd55bb21b1719d89208e659 270 Pfam PF04586 Caudovirus prohead serine protease 51 177 3.3E-5 T 30-10-2018 IPR006433 Prohead protease OTK52_142 bfb9dfd09c8a4eacf03e31197b66730b 374 Pfam PF00268 Ribonucleotide reductase, small chain 45 327 1.5E-44 T 30-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 OTK52_142 bfb9dfd09c8a4eacf03e31197b66730b 374 Gene3D G3DSA:1.10.620.20 30 338 8.5E-68 T 30-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 OTK52_142 bfb9dfd09c8a4eacf03e31197b66730b 374 SUPERFAMILY SSF47240 33 338 2.55E-55 T 30-10-2018 IPR009078 Ferritin-like superfamily OTK52_96 7333bfdc8c61c807fd56ebfe65e323c3 220 Gene3D G3DSA:2.40.40.10 70 201 4.4E-7 T 30-10-2018 IPR036908 RlpA-like domain superfamily OTK52_96 7333bfdc8c61c807fd56ebfe65e323c3 220 Pfam PF06725 3D domain 159 220 8.9E-21 T 30-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 OTK52_96 7333bfdc8c61c807fd56ebfe65e323c3 220 SUPERFAMILY SSF50685 150 200 5.58E-9 T 30-10-2018 IPR036908 RlpA-like domain superfamily OTK52_126 2f597031264370aa7c54969051ab6519 360 SMART SM00400 25 76 0.0046 T 30-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 OTK52_126 2f597031264370aa7c54969051ab6519 360 Gene3D G3DSA:3.90.580.10 2 83 7.1E-11 T 30-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 OTK52_126 2f597031264370aa7c54969051ab6519 360 Gene3D G3DSA:3.40.1360.10 230 346 5.4E-8 T 30-10-2018 OTK52_126 2f597031264370aa7c54969051ab6519 360 SUPERFAMILY SSF56731 141 344 3.14E-18 T 30-10-2018 OTK52_126 2f597031264370aa7c54969051ab6519 360 Pfam PF01807 CHC2 zinc finger 23 73 5.5E-6 T 30-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 OTK52_126 2f597031264370aa7c54969051ab6519 360 SUPERFAMILY SSF57783 15 75 5.78E-14 T 30-10-2018 OTK52_63 a9ace7b826225e5e457c79bfe37c768d 598 Gene3D G3DSA:3.40.50.300 54 230 3.9E-11 T 30-10-2018 OTK52_63 a9ace7b826225e5e457c79bfe37c768d 598 Pfam PF05876 Phage terminase large subunit (GpA) 66 426 5.4E-25 T 30-10-2018 IPR008866 Bacteriophage lambda, GpA OTK52_114 9234e3367b5a1e8b330461ea9cc0a00b 278 Gene3D G3DSA:1.10.10.10 48 143 6.1E-8 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily OTK52_34 9c47dd482fbe2235fca8dce782f67a87 87 SUPERFAMILY SSF57850 4 62 1.93E-5 T 30-10-2018 OTK52_17 32f61795090a8704116f36dc2c7c30ff 395 Pfam PF01139 tRNA-splicing ligase RtcB 130 393 7.9E-54 T 30-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 OTK52_17 32f61795090a8704116f36dc2c7c30ff 395 Pfam PF01139 tRNA-splicing ligase RtcB 38 111 1.4E-12 T 30-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 OTK52_17 32f61795090a8704116f36dc2c7c30ff 395 Gene3D G3DSA:3.90.1860.10 5 394 1.0E-70 T 30-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 OTK52_17 32f61795090a8704116f36dc2c7c30ff 395 SUPERFAMILY SSF103365 3 394 2.62E-105 T 30-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 OTK52_203 7cf5d55b55b3af00c9af111dd5d54764 247 SUPERFAMILY SSF54171 174 215 2.22E-6 T 30-10-2018 IPR016177 DNA-binding domain superfamily GO:0003677 OTK52_203 7cf5d55b55b3af00c9af111dd5d54764 247 Pfam PF00847 AP2 domain 174 216 2.5E-4 T 30-10-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 OTK52_111 da1f07f459f5ce6d39786ce3a2f073f5 1180 Pfam PF16075 Domain of unknown function (DUF4815) 11 628 7.1E-150 T 30-10-2018 IPR032096 Domain of unknown function DUF4815 OTK52_100 25f66a17eb3b6e16adb5f507f8c6adbf 746 SUPERFAMILY SSF54001 603 743 2.45E-20 T 30-10-2018 IPR038765 Papain-like cysteine peptidase superfamily OTK52_100 25f66a17eb3b6e16adb5f507f8c6adbf 746 Pfam PF00877 NlpC/P60 family 616 741 2.9E-17 T 30-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain OTK52_100 25f66a17eb3b6e16adb5f507f8c6adbf 746 Gene3D G3DSA:3.90.1720.10 598 745 1.9E-23 T 30-10-2018 OTK52_238 d0cf38137327d0cd5d9cf46de4fc2fc4 226 Gene3D G3DSA:1.20.5.340 33 170 2.2E-9 T 30-10-2018 OTK52_238 d0cf38137327d0cd5d9cf46de4fc2fc4 226 SUPERFAMILY SSF90257 57 169 4.97E-8 T 30-10-2018 OTK52_122 7c3889c4febd33a4b1466f79f65bc8f2 195 SUPERFAMILY SSF53098 9 189 5.84E-14 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily OTK52_122 7c3889c4febd33a4b1466f79f65bc8f2 195 Pfam PF16473 3' exoribonuclease, RNase T-like 8 185 1.0E-30 T 30-10-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain OTK52_122 7c3889c4febd33a4b1466f79f65bc8f2 195 Gene3D G3DSA:3.30.420.10 1 190 3.3E-15 T 30-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 OTK52_145 fe96d6acf1731dd236b4fbe69117a037 89 SUPERFAMILY SSF52833 9 64 7.09E-7 T 30-10-2018 IPR036249 Thioredoxin-like superfamily OTK52_154 0ce36b51d03b7eec7c44b43e7fd4957d 61 Pfam PF13783 Domain of unknown function (DUF4177) 4 37 3.8E-6 T 30-10-2018 IPR025234 Protein of unknown function DUF4177 OTK52_188 d42f44d044717b129820529f1aba6d0b 100 Pfam PF04688 SPP1 phage holin 20 89 4.8E-14 T 30-10-2018 IPR006479 Holin OTK52_133 f2a49103baba2929bba0152037a063e3 187 ProDom PD927567 D14 PHAGE GP54 SPO1 GENE ORF78 ORF063 ORF064 8 132 6.0E-20 T 30-10-2018