PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 3 695 1.2E-296 T 30-10-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 90 683 1.5E-155 T 30-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 Gene3D G3DSA:1.10.1650.20 281 333 3.5E-174 T 30-10-2018 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 86 158 9.2E-13 T 30-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 Pfam PF08343 Ribonucleotide reductase N-terminal 4 84 2.6E-27 T 30-10-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 Gene3D G3DSA:3.20.70.20 147 681 3.5E-174 T 30-10-2018 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 SUPERFAMILY SSF51998 162 684 7.02E-162 T 30-10-2018 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 PRINTS PR01183 Ribonucleotide reductase large chain signature 482 505 3.1E-24 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 PRINTS PR01183 Ribonucleotide reductase large chain signature 371 382 3.1E-24 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 PRINTS PR01183 Ribonucleotide reductase large chain signature 564 591 3.1E-24 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 PRINTS PR01183 Ribonucleotide reductase large chain signature 238 257 3.1E-24 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 PRINTS PR01183 Ribonucleotide reductase large chain signature 454 476 3.1E-24 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 SUPERFAMILY SSF48168 3 158 2.35E-46 T 30-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 PBC2_133 9d2e020b1b48f3387b28244b48be3d4c 695 Pfam PF02867 Ribonucleotide reductase, barrel domain 163 679 2.2E-131 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 PBC2_110 4818e77c093589615cbdba46081c7bec 243 Pfam PF14072 DNA-sulfur modification-associated 17 236 2.7E-9 T 30-10-2018 IPR017642 DNA sulphur modification protein DndB PBC2_241 8aa93ad1c1fbcc6e1af2c623218d03d1 337 SUPERFAMILY SSF56349 30 286 3.53E-32 T 30-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 PBC2_241 8aa93ad1c1fbcc6e1af2c623218d03d1 337 Gene3D G3DSA:1.10.150.130 19 110 2.3E-8 T 30-10-2018 IPR010998 Integrase/recombinase, N-terminal PBC2_241 8aa93ad1c1fbcc6e1af2c623218d03d1 337 Gene3D G3DSA:1.10.443.10 129 300 2.9E-19 T 30-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 PBC2_241 8aa93ad1c1fbcc6e1af2c623218d03d1 337 Pfam PF00589 Phage integrase family 129 287 7.1E-14 T 30-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 PBC2_241 8aa93ad1c1fbcc6e1af2c623218d03d1 337 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 30 103 6.4E-7 T 30-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 PBC2_130 4454fd1c338f81db5c9363e7290a36fb 152 TIGRFAM TIGR00333 nrdI: nrdI protein 37 148 5.3E-30 T 30-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI PBC2_130 4454fd1c338f81db5c9363e7290a36fb 152 PIRSF PIRSF005087 33 152 1.9E-32 T 30-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI PBC2_130 4454fd1c338f81db5c9363e7290a36fb 152 Gene3D G3DSA:3.40.50.360 35 152 1.1E-33 T 30-10-2018 IPR029039 Flavoprotein-like superfamily PBC2_130 4454fd1c338f81db5c9363e7290a36fb 152 Pfam PF07972 NrdI Flavodoxin like 37 144 8.6E-25 T 30-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI PBC2_130 4454fd1c338f81db5c9363e7290a36fb 152 SUPERFAMILY SSF52218 33 149 4.47E-16 T 30-10-2018 IPR029039 Flavoprotein-like superfamily PBC2_139 858eec3c9bd888380eb130f4d8bad14c 237 Gene3D G3DSA:3.10.28.10 134 237 1.7E-10 T 30-10-2018 IPR027434 Homing endonuclease PBC2_139 858eec3c9bd888380eb130f4d8bad14c 237 Pfam PF03161 LAGLIDADG DNA endonuclease family 58 208 1.7E-21 T 30-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 PBC2_139 858eec3c9bd888380eb130f4d8bad14c 237 Gene3D G3DSA:1.10.10.60 2 41 4.5E-5 T 30-10-2018 PBC2_139 858eec3c9bd888380eb130f4d8bad14c 237 SUPERFAMILY SSF55608 45 236 1.02E-25 T 30-10-2018 IPR027434 Homing endonuclease PBC2_232 2e44635c3fcd1c96b73a282d398b7ec4 94 Gene3D G3DSA:1.20.5.320 43 87 1.7E-5 T 30-10-2018 PBC2_126 ceda4fa99cf5fda0539556b6f7937ed4 713 SMART SM00434 7 454 1.8E-98 T 30-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 PBC2_126 ceda4fa99cf5fda0539556b6f7937ed4 713 SUPERFAMILY SSF101904 492 707 3.14E-31 T 30-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal PBC2_126 ceda4fa99cf5fda0539556b6f7937ed4 713 Gene3D G3DSA:2.120.10.90 491 713 1.4E-26 T 30-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal PBC2_126 ceda4fa99cf5fda0539556b6f7937ed4 713 Gene3D G3DSA:3.90.199.10 15 468 4.2E-141 T 30-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 PBC2_126 ceda4fa99cf5fda0539556b6f7937ed4 713 SUPERFAMILY SSF56719 5 477 1.7E-109 T 30-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 PBC2_126 ceda4fa99cf5fda0539556b6f7937ed4 713 Gene3D G3DSA:1.10.268.10 359 448 4.2E-141 T 30-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 PBC2_126 ceda4fa99cf5fda0539556b6f7937ed4 713 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 28 461 1.2E-107 T 30-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 PBC2_126 ceda4fa99cf5fda0539556b6f7937ed4 713 Gene3D G3DSA:3.30.1360.40 231 322 4.2E-141 T 30-10-2018 PBC2_230 b070ffb93b6239bf5ae29c60bb7d34e8 176 SUPERFAMILY SSF54060 3 76 4.59E-6 T 30-10-2018 PBC2_230 b070ffb93b6239bf5ae29c60bb7d34e8 176 Pfam PF13392 HNH endonuclease 26 71 1.1E-7 T 30-10-2018 IPR003615 HNH nuclease PBC2_085 26ec143deb7260c082485016af00b779 511 SUPERFAMILY SSF52540 205 424 1.45E-6 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase PBC2_085 26ec143deb7260c082485016af00b779 511 Gene3D G3DSA:3.40.50.300 182 486 1.1E-22 T 30-10-2018 PBC2_085 26ec143deb7260c082485016af00b779 511 Gene3D G3DSA:1.10.860.10 13 139 3.2E-5 T 30-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal PBC2_091 a97c5db2d92f9bda4bfd25a04dc17cee 247 Pfam PF01541 GIY-YIG catalytic domain 5 86 4.6E-12 T 30-10-2018 IPR000305 GIY-YIG endonuclease PBC2_091 a97c5db2d92f9bda4bfd25a04dc17cee 247 SMART SM00465 4 96 4.5E-13 T 30-10-2018 IPR000305 GIY-YIG endonuclease PBC2_091 a97c5db2d92f9bda4bfd25a04dc17cee 247 Pfam PF07460 NUMOD3 motif (2 copies) 131 155 5.2E-7 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 PBC2_091 a97c5db2d92f9bda4bfd25a04dc17cee 247 Pfam PF07460 NUMOD3 motif (2 copies) 160 185 4.2E-4 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 PBC2_091 a97c5db2d92f9bda4bfd25a04dc17cee 247 SMART SM00496 159 175 0.05 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 PBC2_091 a97c5db2d92f9bda4bfd25a04dc17cee 247 SMART SM00496 142 158 0.0058 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 PBC2_091 a97c5db2d92f9bda4bfd25a04dc17cee 247 SMART SM00496 118 134 1900.0 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 PBC2_091 a97c5db2d92f9bda4bfd25a04dc17cee 247 SMART SM00497 186 238 4.4E-4 T 30-10-2018 IPR003647 Intron encoded nuclease repeat PBC2_091 a97c5db2d92f9bda4bfd25a04dc17cee 247 SUPERFAMILY SSF64496 121 230 8.76E-10 T 30-10-2018 PBC2_091 a97c5db2d92f9bda4bfd25a04dc17cee 247 SUPERFAMILY SSF82771 5 96 2.35E-14 T 30-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 PBC2_091 a97c5db2d92f9bda4bfd25a04dc17cee 247 Gene3D G3DSA:3.40.1440.10 5 97 1.8E-17 T 30-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 PBC2_091 a97c5db2d92f9bda4bfd25a04dc17cee 247 TIGRFAM TIGR01453 grpIintron_endo: group I intron endonuclease 6 238 1.2E-32 T 30-10-2018 IPR006350 Intron endonuclease, group I GO:0004519 PBC2_190 d2ef639eba6c2b34de4d46748f8f52f6 320 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 141 210 3.4E-10 T 30-10-2018 PBC2_190 d2ef639eba6c2b34de4d46748f8f52f6 320 Gene3D G3DSA:2.60.120.200 29 219 9.0E-15 T 30-10-2018 PBC2_190 d2ef639eba6c2b34de4d46748f8f52f6 320 SUPERFAMILY SSF49899 4 217 5.05E-18 T 30-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily PBC2_250 4a561114e42a936d5384bfa6ed6218df 278 SUPERFAMILY SSF53067 8 158 4.99E-7 T 30-10-2018 PBC2_250 4a561114e42a936d5384bfa6ed6218df 278 Gene3D G3DSA:3.30.420.40 5 176 3.5E-12 T 30-10-2018 PBC2_251 902f2843bdb0058e2dc565e344be3db8 759 Gene3D G3DSA:1.10.10.2220 198 298 4.5E-14 T 30-10-2018 PBC2_251 902f2843bdb0058e2dc565e344be3db8 759 Gene3D G3DSA:3.40.50.300 487 724 5.4E-96 T 30-10-2018 PBC2_251 902f2843bdb0058e2dc565e344be3db8 759 SUPERFAMILY SSF52540 440 733 1.53E-47 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase PBC2_251 902f2843bdb0058e2dc565e344be3db8 759 Pfam PF14490 Helix-hairpin-helix containing domain 158 246 4.4E-21 T 30-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain PBC2_251 902f2843bdb0058e2dc565e344be3db8 759 Gene3D G3DSA:3.40.50.300 326 729 5.4E-96 T 30-10-2018 PBC2_251 902f2843bdb0058e2dc565e344be3db8 759 SUPERFAMILY SSF52540 199 487 7.87E-26 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase PBC2_251 902f2843bdb0058e2dc565e344be3db8 759 Gene3D G3DSA:2.30.30.940 576 661 5.4E-96 T 30-10-2018 PBC2_251 902f2843bdb0058e2dc565e344be3db8 759 Pfam PF13538 UvrD-like helicase C-terminal domain 660 707 1.5E-15 T 30-10-2018 IPR027785 UvrD-like helicase C-terminal domain PBC2_251 902f2843bdb0058e2dc565e344be3db8 759 Pfam PF13604 AAA domain 332 505 1.5E-32 T 30-10-2018 PBC2_098 8ee70400927c2bf62470b098aecfffa9 143 Gene3D G3DSA:3.40.220.10 1 143 2.6E-31 T 30-10-2018 PBC2_098 8ee70400927c2bf62470b098aecfffa9 143 Pfam PF01661 Macro domain 11 128 1.8E-5 T 30-10-2018 IPR002589 Macro domain PBC2_098 8ee70400927c2bf62470b098aecfffa9 143 SUPERFAMILY SSF52949 5 141 6.39E-25 T 30-10-2018 PBC2_053 3bb9eeca00b43fa6d23149fb7b1e594a 342 SUPERFAMILY SSF52374 3 169 3.52E-17 T 30-10-2018 PBC2_053 3bb9eeca00b43fa6d23149fb7b1e594a 342 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 63 3.2E-10 T 30-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 PBC2_053 3bb9eeca00b43fa6d23149fb7b1e594a 342 Gene3D G3DSA:3.40.50.620 2 167 3.2E-35 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold PBC2_053 3bb9eeca00b43fa6d23149fb7b1e594a 342 SUPERFAMILY SSF52540 166 332 4.1E-22 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase PBC2_053 3bb9eeca00b43fa6d23149fb7b1e594a 342 Gene3D G3DSA:3.40.50.300 168 334 1.8E-50 T 30-10-2018 PBC2_053 3bb9eeca00b43fa6d23149fb7b1e594a 342 Pfam PF13521 AAA domain 170 329 3.9E-32 T 30-10-2018 IPR038727 NadR/Ttd14, AAA domain PBC2_053 3bb9eeca00b43fa6d23149fb7b1e594a 342 PIRSF PIRSF004776 1 342 2.3E-78 T 30-10-2018 IPR016429 Bifunctional transcriptional regulator NadR GO:0045892 KEGG: 00760+2.7.7.1+2.7.1.22 PBC2_124 8b39f203ea8c7e28b5f8919462c2f9df 200 SUPERFAMILY SSF54060 15 48 4.12E-7 T 30-10-2018 PBC2_124 8b39f203ea8c7e28b5f8919462c2f9df 200 Pfam PF00847 AP2 domain 52 92 3.3E-4 T 30-10-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 PBC2_124 8b39f203ea8c7e28b5f8919462c2f9df 200 Pfam PF13392 HNH endonuclease 16 42 7.1E-6 T 30-10-2018 IPR003615 HNH nuclease PBC2_124 8b39f203ea8c7e28b5f8919462c2f9df 200 SUPERFAMILY SSF54171 54 107 3.92E-5 T 30-10-2018 IPR016177 DNA-binding domain superfamily GO:0003677 PBC2_134 816ae390b6961230d1870ded831010b2 354 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 29 350 2.6E-134 T 30-10-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 PBC2_134 816ae390b6961230d1870ded831010b2 354 Pfam PF00268 Ribonucleotide reductase, small chain 31 311 1.7E-71 T 30-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 PBC2_134 816ae390b6961230d1870ded831010b2 354 SUPERFAMILY SSF47240 25 348 2.66E-83 T 30-10-2018 IPR009078 Ferritin-like superfamily PBC2_134 816ae390b6961230d1870ded831010b2 354 Gene3D G3DSA:1.10.620.20 26 320 1.8E-92 T 30-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 PBC2_134 816ae390b6961230d1870ded831010b2 354 PIRSF PIRSF000355 3 346 1.5E-76 T 30-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 PBC2_132 21cb4963601bd9a3a321c326a671e8be 158 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 3 108 6.8E-18 T 30-10-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase Reactome: R-HSA-74259 PBC2_132 21cb4963601bd9a3a321c326a671e8be 158 Gene3D G3DSA:3.40.50.450 1 156 2.0E-41 T 30-10-2018 PBC2_132 21cb4963601bd9a3a321c326a671e8be 158 SUPERFAMILY SSF52309 1 136 9.16E-23 T 30-10-2018 PBC2_102 3445ab0d515243fe0d3ddec287ee1632 189 Pfam PF01541 GIY-YIG catalytic domain 8 81 5.4E-14 T 30-10-2018 IPR000305 GIY-YIG endonuclease PBC2_102 3445ab0d515243fe0d3ddec287ee1632 189 Gene3D G3DSA:3.40.1440.10 5 90 6.6E-15 T 30-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 PBC2_102 3445ab0d515243fe0d3ddec287ee1632 189 SUPERFAMILY SSF82771 7 83 1.57E-13 T 30-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 PBC2_102 3445ab0d515243fe0d3ddec287ee1632 189 SMART SM00465 6 86 2.8E-8 T 30-10-2018 IPR000305 GIY-YIG endonuclease PBC2_102 3445ab0d515243fe0d3ddec287ee1632 189 SUPERFAMILY SSF46785 107 167 3.32E-5 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily PBC2_176 e703153a9df36ef6f9e33b9d27db3ac7 122 Gene3D G3DSA:3.40.50.1000 4 121 8.3E-28 T 30-10-2018 IPR023214 HAD superfamily PBC2_176 e703153a9df36ef6f9e33b9d27db3ac7 122 SUPERFAMILY SSF56784 6 111 1.01E-16 T 30-10-2018 IPR036412 HAD-like superfamily PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 SMART SM00433 29 644 9.5E-71 T 30-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 SUPERFAMILY SSF54211 216 396 2.47E-19 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 Pfam PF01751 Toprim domain 430 549 5.3E-17 T 30-10-2018 IPR006171 TOPRIM domain PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 Gene3D G3DSA:3.30.565.10 1 215 7.7E-39 T 30-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR00418 DNA topoisomerase II family signature 430 444 1.6E-32 T 30-10-2018 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR00418 DNA topoisomerase II family signature 543 555 1.6E-32 T 30-10-2018 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR00418 DNA topoisomerase II family signature 523 540 1.6E-32 T 30-10-2018 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR00418 DNA topoisomerase II family signature 29 44 1.6E-32 T 30-10-2018 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR00418 DNA topoisomerase II family signature 505 521 1.6E-32 T 30-10-2018 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR00418 DNA topoisomerase II family signature 64 77 1.6E-32 T 30-10-2018 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR00418 DNA topoisomerase II family signature 583 599 1.6E-32 T 30-10-2018 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 SUPERFAMILY SSF55874 2 199 3.7E-20 T 30-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 Gene3D G3DSA:3.40.50.670 417 651 3.2E-77 T 30-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 SUPERFAMILY SSF56719 416 647 1.94E-64 T 30-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 Pfam PF00204 DNA gyrase B 216 396 5.0E-24 T 30-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 580 640 2.3E-21 T 30-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR01159 DNA gyrase subunit B signature 381 401 3.5E-12 T 30-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR01159 DNA gyrase subunit B signature 215 237 3.5E-12 T 30-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR01159 DNA gyrase subunit B signature 480 489 3.5E-12 T 30-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR01159 DNA gyrase subunit B signature 319 335 3.5E-12 T 30-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR01159 DNA gyrase subunit B signature 604 616 3.5E-12 T 30-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 PRINTS PR01159 DNA gyrase subunit B signature 620 636 3.5E-12 T 30-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 PBC2_125 8ca3f4d24c7bc41a2f075aba5c5becf8 652 Gene3D G3DSA:3.30.230.10 216 397 5.9E-27 T 30-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup PBC2_173 1ea6820d0de482750ad433ec158767d3 144 Gene3D G3DSA:1.10.1510.10 1 90 1.4E-12 T 30-10-2018 PBC2_173 1ea6820d0de482750ad433ec158767d3 144 Gene3D G3DSA:1.10.10.410 91 144 6.6E-10 T 30-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal PBC2_173 1ea6820d0de482750ad433ec158767d3 144 Pfam PF09424 Yqey-like protein 3 142 5.4E-26 T 30-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 PBC2_173 1ea6820d0de482750ad433ec158767d3 144 SUPERFAMILY SSF89095 2 143 3.03E-19 T 30-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 PBC2_226 8405c32587785b63b00599aba0cdb41c 67 Pfam PF09642 YonK protein 8 56 6.3E-7 T 30-10-2018 IPR018600 Bacillus phage SPbeta, YonK PBC2_226 8405c32587785b63b00599aba0cdb41c 67 SUPERFAMILY SSF160570 3 56 3.01E-7 T 30-10-2018 IPR037261 YonK superfamily PBC2_226 8405c32587785b63b00599aba0cdb41c 67 Gene3D G3DSA:2.40.50.280 1 66 1.1E-12 T 30-10-2018 IPR037261 YonK superfamily PBC2_135 58338be830a5597ed13aef3d12ed00a2 103 Gene3D G3DSA:3.40.30.10 3 82 3.6E-7 T 30-10-2018 PBC2_135 58338be830a5597ed13aef3d12ed00a2 103 SUPERFAMILY SSF52833 7 62 1.33E-7 T 30-10-2018 IPR036249 Thioredoxin-like superfamily PBC2_180 e1a5de49a5c20c21583dd8f3d687b0cf 178 Pfam PF00186 Dihydrofolate reductase 1 161 2.5E-53 T 30-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 PBC2_180 e1a5de49a5c20c21583dd8f3d687b0cf 178 PIRSF PIRSF000194 1 164 1.5E-51 T 30-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 PBC2_180 e1a5de49a5c20c21583dd8f3d687b0cf 178 Gene3D G3DSA:3.40.430.10 1 176 5.9E-56 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 PBC2_180 e1a5de49a5c20c21583dd8f3d687b0cf 178 PRINTS PR00070 Dihydrofolate reductase signature 28 36 7.3E-13 T 30-10-2018 PBC2_180 e1a5de49a5c20c21583dd8f3d687b0cf 178 PRINTS PR00070 Dihydrofolate reductase signature 92 106 7.3E-13 T 30-10-2018 PBC2_180 e1a5de49a5c20c21583dd8f3d687b0cf 178 PRINTS PR00070 Dihydrofolate reductase signature 41 52 7.3E-13 T 30-10-2018 PBC2_180 e1a5de49a5c20c21583dd8f3d687b0cf 178 SUPERFAMILY SSF53597 1 162 1.96E-49 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 PBC2_170 acf77f8060dc5e24c35f4593e01c1a96 498 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 187 480 1.7E-48 T 30-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 PBC2_170 acf77f8060dc5e24c35f4593e01c1a96 498 PIRSF PIRSF005943 2 498 2.4E-171 T 30-10-2018 IPR016471 Nicotinamide phosphoribosyl transferase Reactome: R-HSA-1368108|Reactome: R-HSA-197264 PBC2_170 acf77f8060dc5e24c35f4593e01c1a96 498 Gene3D G3DSA:3.20.20.70 153 421 3.3E-96 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 PBC2_170 acf77f8060dc5e24c35f4593e01c1a96 498 SUPERFAMILY SSF51690 157 497 6.08E-41 T 30-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 PBC2_137 92d523487e2065ce0f0a6140769c55c7 267 SUPERFAMILY SSF51283 96 203 3.93E-14 T 30-10-2018 IPR036157 dUTPase-like superfamily PBC2_137 92d523487e2065ce0f0a6140769c55c7 267 Pfam PF00692 dUTPase 113 203 2.2E-4 T 30-10-2018 IPR029054 dUTPase-like PBC2_137 92d523487e2065ce0f0a6140769c55c7 267 Gene3D G3DSA:2.70.40.10 92 267 1.5E-23 T 30-10-2018 IPR036157 dUTPase-like superfamily PBC2_229 2e0c4ae17536e70e7d1ca75ff1e89961 490 Gene3D G3DSA:3.40.50.410 294 424 2.0E-5 T 30-10-2018 IPR036465 von Willebrand factor A-like domain superfamily PBC2_229 2e0c4ae17536e70e7d1ca75ff1e89961 490 SUPERFAMILY SSF53300 298 404 1.22E-8 T 30-10-2018 IPR036465 von Willebrand factor A-like domain superfamily PBC2_229 2e0c4ae17536e70e7d1ca75ff1e89961 490 Pfam PF11443 Domain of unknown function (DUF2828) 153 469 6.0E-71 T 30-10-2018 IPR024553 Domain of unknown function DUF2828 PBC2_229 2e0c4ae17536e70e7d1ca75ff1e89961 490 Pfam PF11443 Domain of unknown function (DUF2828) 14 140 2.7E-15 T 30-10-2018 IPR024553 Domain of unknown function DUF2828 PBC2_229 2e0c4ae17536e70e7d1ca75ff1e89961 490 PIRSF PIRSF015417 118 415 4.8E-41 T 30-10-2018 IPR011205 Uncharacterised conserved protein UCP015417, vWA PBC2_229 2e0c4ae17536e70e7d1ca75ff1e89961 490 PIRSF PIRSF015417 408 490 3.8E-12 T 30-10-2018 IPR011205 Uncharacterised conserved protein UCP015417, vWA PBC2_229 2e0c4ae17536e70e7d1ca75ff1e89961 490 PIRSF PIRSF015417 7 168 0.029 T 30-10-2018 IPR011205 Uncharacterised conserved protein UCP015417, vWA PBC2_082 34a78ecf4f6c57329b729d07443131f9 256 SUPERFAMILY SSF50685 197 241 2.69E-7 T 30-10-2018 IPR036908 RlpA-like domain superfamily PBC2_082 34a78ecf4f6c57329b729d07443131f9 256 Pfam PF06725 3D domain 197 256 4.0E-16 T 30-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 PBC2_186 3ffc2794e3b50d4526f3d7cc39d1dc7d 1113 SUPERFAMILY SSF89550 7 274 2.62E-18 T 30-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 PBC2_186 3ffc2794e3b50d4526f3d7cc39d1dc7d 1113 SMART SM00481 5 83 1.2E-10 T 30-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal PBC2_186 3ffc2794e3b50d4526f3d7cc39d1dc7d 1113 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 327 742 3.6E-80 T 30-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 PBC2_186 3ffc2794e3b50d4526f3d7cc39d1dc7d 1113 Gene3D G3DSA:3.20.20.140 1 300 3.6E-54 T 30-10-2018 PBC2_186 3ffc2794e3b50d4526f3d7cc39d1dc7d 1113 Pfam PF02811 PHP domain 7 202 2.2E-23 T 30-10-2018 IPR004013 PHP domain GO:0003824 PBC2_178 5bd510000124a714eca8693743f009a2 288 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 99 288 6.0E-50 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 PBC2_178 5bd510000124a714eca8693743f009a2 288 Pfam PF00303 Thymidylate synthase 8 288 2.7E-90 T 30-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 PBC2_178 5bd510000124a714eca8693743f009a2 288 PRINTS PR00108 Thymidylate synthase family signature 139 158 6.9E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 PBC2_178 5bd510000124a714eca8693743f009a2 288 PRINTS PR00108 Thymidylate synthase family signature 221 238 6.9E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 PBC2_178 5bd510000124a714eca8693743f009a2 288 PRINTS PR00108 Thymidylate synthase family signature 54 75 6.9E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 PBC2_178 5bd510000124a714eca8693743f009a2 288 PRINTS PR00108 Thymidylate synthase family signature 183 209 6.9E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 PBC2_178 5bd510000124a714eca8693743f009a2 288 PRINTS PR00108 Thymidylate synthase family signature 165 180 6.9E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 PBC2_178 5bd510000124a714eca8693743f009a2 288 Hamap MF_00008 Thymidylate synthase [thyA]. 5 288 37.583 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 PBC2_178 5bd510000124a714eca8693743f009a2 288 Gene3D G3DSA:3.30.572.10 2 288 7.4E-110 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 PBC2_178 5bd510000124a714eca8693743f009a2 288 ProSitePatterns PS00091 Thymidylate synthase active site. 150 178 - T 30-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 PBC2_178 5bd510000124a714eca8693743f009a2 288 SUPERFAMILY SSF55831 4 288 6.67E-94 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 PBC2_225 ded93b23e36907a850b632482e005149 413 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 162 378 1.4E-6 T 30-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 PBC2_225 ded93b23e36907a850b632482e005149 413 Gene3D G3DSA:3.60.21.10 184 413 2.8E-15 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like PBC2_225 ded93b23e36907a850b632482e005149 413 SUPERFAMILY SSF56300 158 375 2.69E-16 T 30-10-2018 PBC2_143 0925b7102a3175037f7ca8952d63f559 183 Gene3D G3DSA:3.40.50.300 5 164 3.0E-34 T 30-10-2018 PBC2_143 0925b7102a3175037f7ca8952d63f559 183 ProSitePatterns PS00856 Guanylate kinase-like signature. 37 54 - T 30-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 PBC2_143 0925b7102a3175037f7ca8952d63f559 183 SMART SM00072 1 178 2.6E-12 T 30-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit PBC2_143 0925b7102a3175037f7ca8952d63f559 183 Gene3D G3DSA:3.30.63.10 34 91 3.0E-34 T 30-10-2018 PBC2_143 0925b7102a3175037f7ca8952d63f559 183 Pfam PF00625 Guanylate kinase 3 178 1.0E-24 T 30-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit PBC2_143 0925b7102a3175037f7ca8952d63f559 183 SUPERFAMILY SSF52540 3 178 2.86E-34 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase PBC2_197 fe67289ec1f269257625fadb207a9519 311 SMART SM00644 15 152 3.8E-37 T 30-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 PBC2_197 fe67289ec1f269257625fadb207a9519 311 Pfam PF08239 Bacterial SH3 domain 188 234 5.2E-7 T 30-10-2018 IPR003646 SH3-like domain, bacterial-type PBC2_197 fe67289ec1f269257625fadb207a9519 311 SMART SM00287 249 307 0.38 T 30-10-2018 IPR003646 SH3-like domain, bacterial-type PBC2_197 fe67289ec1f269257625fadb207a9519 311 SMART SM00287 179 237 0.11 T 30-10-2018 IPR003646 SH3-like domain, bacterial-type PBC2_197 fe67289ec1f269257625fadb207a9519 311 Gene3D G3DSA:3.40.80.10 3 163 3.2E-49 T 30-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 PBC2_197 fe67289ec1f269257625fadb207a9519 311 Gene3D G3DSA:2.30.30.40 177 238 9.1E-10 T 30-10-2018 PBC2_197 fe67289ec1f269257625fadb207a9519 311 SUPERFAMILY SSF55846 7 157 3.74E-48 T 30-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 PBC2_197 fe67289ec1f269257625fadb207a9519 311 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 25 141 7.4E-18 T 30-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 PBC2_197 fe67289ec1f269257625fadb207a9519 311 Gene3D G3DSA:2.30.30.40 254 304 1.8E-6 T 30-10-2018 PBC2_156 b77951ff10451a5712c053f117459f7e 286 SUPERFAMILY SSF52743 20 285 1.57E-83 T 30-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 PBC2_156 b77951ff10451a5712c053f117459f7e 286 Pfam PF00082 Subtilase family 38 277 5.0E-45 T 30-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 PBC2_156 b77951ff10451a5712c053f117459f7e 286 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 80 90 - T 30-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site PBC2_156 b77951ff10451a5712c053f117459f7e 286 Gene3D G3DSA:3.40.50.200 2 286 1.5E-82 T 30-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 PBC2_156 b77951ff10451a5712c053f117459f7e 286 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 227 237 - T 30-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site PBC2_156 b77951ff10451a5712c053f117459f7e 286 PRINTS PR00723 Subtilisin serine protease family (S8) signature 38 57 2.4E-21 T 30-10-2018 IPR015500 Peptidase S8, subtilisin-related PBC2_156 b77951ff10451a5712c053f117459f7e 286 PRINTS PR00723 Subtilisin serine protease family (S8) signature 76 89 2.4E-21 T 30-10-2018 IPR015500 Peptidase S8, subtilisin-related PBC2_156 b77951ff10451a5712c053f117459f7e 286 PRINTS PR00723 Subtilisin serine protease family (S8) signature 226 242 2.4E-21 T 30-10-2018 IPR015500 Peptidase S8, subtilisin-related PBC2_120 4dc1f8b1f496c0865ca99ff0e3d60861 162 Gene3D G3DSA:1.10.357.40 3 162 4.6E-34 T 30-10-2018 IPR037238 YbiA-like superfamily PBC2_120 4dc1f8b1f496c0865ca99ff0e3d60861 162 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 10 161 1.8E-44 T 30-10-2018 IPR012816 NADAR PBC2_120 4dc1f8b1f496c0865ca99ff0e3d60861 162 Pfam PF08719 Domain of unknown function (DUF1768) 12 161 3.8E-40 T 30-10-2018 IPR012816 NADAR PBC2_120 4dc1f8b1f496c0865ca99ff0e3d60861 162 SUPERFAMILY SSF143990 6 161 4.32E-37 T 30-10-2018 IPR037238 YbiA-like superfamily PBC2_166 00981300cf0d9455c4884b5f8c2e027e 294 Gene3D G3DSA:3.40.50.2020 2 130 2.6E-10 T 30-10-2018 PBC2_166 00981300cf0d9455c4884b5f8c2e027e 294 SUPERFAMILY SSF53271 150 292 9.83E-11 T 30-10-2018 IPR029057 Phosphoribosyltransferase-like PBC2_166 00981300cf0d9455c4884b5f8c2e027e 294 Gene3D G3DSA:3.40.50.2020 131 278 2.8E-18 T 30-10-2018 PBC2_184 3f06cf0d12a9a0bd0238c909dede76f2 204 SUPERFAMILY SSF52540 5 127 2.94E-17 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase PBC2_184 3f06cf0d12a9a0bd0238c909dede76f2 204 Pfam PF00265 Thymidine kinase 5 188 1.5E-21 T 30-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 PBC2_184 3f06cf0d12a9a0bd0238c909dede76f2 204 PIRSF PIRSF035805 1 203 2.8E-35 T 30-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 PBC2_184 3f06cf0d12a9a0bd0238c909dede76f2 204 Gene3D G3DSA:3.40.50.300 3 137 1.8E-21 T 30-10-2018 PBC2_233 9b11bf2d31a89010c8b12f078799a478 405 SUPERFAMILY SSF88723 1 121 8.97E-12 T 30-10-2018 IPR029060 PIN-like domain superfamily PBC2_233 9b11bf2d31a89010c8b12f078799a478 405 Pfam PF02562 PhoH-like protein 204 400 4.2E-25 T 30-10-2018 IPR003714 PhoH-like protein GO:0005524 PBC2_233 9b11bf2d31a89010c8b12f078799a478 405 Gene3D G3DSA:3.40.50.300 200 404 1.6E-35 T 30-10-2018 PBC2_233 9b11bf2d31a89010c8b12f078799a478 405 Pfam PF13638 PIN domain 3 116 4.1E-9 T 30-10-2018 IPR002716 PIN domain PBC2_233 9b11bf2d31a89010c8b12f078799a478 405 SMART SM00670 1 106 0.0031 T 30-10-2018 IPR002716 PIN domain PBC2_233 9b11bf2d31a89010c8b12f078799a478 405 Gene3D G3DSA:3.40.50.1010 1 127 1.1E-12 T 30-10-2018 PBC2_233 9b11bf2d31a89010c8b12f078799a478 405 SUPERFAMILY SSF52540 55 356 2.54E-10 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase PBC2_160 0c8e6d5c7515e7ac5a799ee62e7c20cd 201 Pfam PF00574 Clp protease 22 196 1.8E-24 T 30-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA PBC2_160 0c8e6d5c7515e7ac5a799ee62e7c20cd 201 SUPERFAMILY SSF52096 62 195 1.46E-31 T 30-10-2018 IPR029045 ClpP/crotonase-like domain superfamily PBC2_160 0c8e6d5c7515e7ac5a799ee62e7c20cd 201 Gene3D G3DSA:3.90.226.10 1 198 1.6E-39 T 30-10-2018 PBC2_160 0c8e6d5c7515e7ac5a799ee62e7c20cd 201 PRINTS PR00127 Clp protease catalytic subunit P signature 95 112 8.9E-13 T 30-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 PBC2_160 0c8e6d5c7515e7ac5a799ee62e7c20cd 201 PRINTS PR00127 Clp protease catalytic subunit P signature 64 84 8.9E-13 T 30-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 PBC2_160 0c8e6d5c7515e7ac5a799ee62e7c20cd 201 PRINTS PR00127 Clp protease catalytic subunit P signature 173 192 8.9E-13 T 30-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 PBC2_157 412c77160ef6d09eec17bfac4f86b876 425 Pfam PF09414 RNA ligase 175 395 4.1E-6 T 30-10-2018 IPR021122 RNA ligase domain, REL/Rln2 PBC2_157 412c77160ef6d09eec17bfac4f86b876 425 SUPERFAMILY SSF56091 149 383 3.6E-8 T 30-10-2018 PBC2_158 db56fac61403daba88d00ecf237328f1 331 SUPERFAMILY SSF52540 4 139 1.03E-13 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase PBC2_158 db56fac61403daba88d00ecf237328f1 331 Pfam PF13671 AAA domain 5 128 4.7E-14 T 30-10-2018 PBC2_158 db56fac61403daba88d00ecf237328f1 331 Gene3D G3DSA:1.10.3210.10 182 331 3.2E-8 T 30-10-2018 PBC2_158 db56fac61403daba88d00ecf237328f1 331 Gene3D G3DSA:3.40.50.300 2 151 1.4E-31 T 30-10-2018 PBC2_158 db56fac61403daba88d00ecf237328f1 331 SUPERFAMILY SSF109604 197 329 6.28E-16 T 30-10-2018 PBC2_158 db56fac61403daba88d00ecf237328f1 331 Pfam PF01966 HD domain 202 300 2.8E-6 T 30-10-2018 IPR006674 HD domain PBC2_047 30788a5136249621fc59836cf3062225 143 Gene3D G3DSA:3.40.50.150 12 140 1.1E-16 T 30-10-2018 PBC2_047 30788a5136249621fc59836cf3062225 143 SUPERFAMILY SSF53335 22 112 3.02E-15 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase PBC2_047 30788a5136249621fc59836cf3062225 143 Pfam PF13489 Methyltransferase domain 40 100 7.8E-11 T 30-10-2018 PBC2_179 153ca1ef9b4b0e709026c2c4868a0a9e 218 SUPERFAMILY SSF54060 91 162 2.0E-9 T 30-10-2018 PBC2_179 153ca1ef9b4b0e709026c2c4868a0a9e 218 Gene3D G3DSA:3.90.75.20 65 165 5.4E-6 T 30-10-2018 PBC2_246 47c742c508bff6297cf42a5ce2d73fef 168 Pfam PF07463 NUMOD4 motif 2 49 9.5E-10 T 30-10-2018 IPR010902 NUMOD4 GO:0016788 PBC2_246 47c742c508bff6297cf42a5ce2d73fef 168 Pfam PF13392 HNH endonuclease 58 101 6.1E-11 T 30-10-2018 IPR003615 HNH nuclease PBC2_246 47c742c508bff6297cf42a5ce2d73fef 168 SUPERFAMILY SSF54060 7 108 6.12E-28 T 30-10-2018 PBC2_246 47c742c508bff6297cf42a5ce2d73fef 168 Gene3D G3DSA:3.90.75.20 3 110 2.6E-32 T 30-10-2018 PBC2_242 66ba0c817d25473319ad5726d8956a9b 288 Pfam PF13814 Replication-relaxation 60 244 8.5E-11 T 30-10-2018 IPR025855 Plasmid replication-relaxation PBC2_086 e976a4528d44833af2339cb050300a47 370 SUPERFAMILY SSF56731 170 299 1.39E-14 T 30-10-2018 PBC2_086 e976a4528d44833af2339cb050300a47 370 Gene3D G3DSA:3.40.1360.10 229 350 7.5E-7 T 30-10-2018 PBC2_234 c3ad1ec7ca2880aff0eeb28512522e7b 99 Gene3D G3DSA:4.10.520.10 1 99 1.5E-15 T 30-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 PBC2_234 c3ad1ec7ca2880aff0eeb28512522e7b 99 SUPERFAMILY SSF47729 2 96 3.53E-15 T 30-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 PBC2_234 c3ad1ec7ca2880aff0eeb28512522e7b 99 SMART SM00411 1 95 1.7E-6 T 30-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 PBC2_234 c3ad1ec7ca2880aff0eeb28512522e7b 99 Pfam PF00216 Bacterial DNA-binding protein 2 94 1.4E-14 T 30-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 PBC2_154 0026ce8f7cd6e7bc34b6ded2b3ef38a5 196 Gene3D G3DSA:3.30.460.10 1 112 1.6E-5 T 30-10-2018 PBC2_154 0026ce8f7cd6e7bc34b6ded2b3ef38a5 196 SUPERFAMILY SSF81301 8 59 2.29E-5 T 30-10-2018 PBC2_209 aeef31d1d434544e9625bff47f73b7dc 325 Gene3D G3DSA:1.10.443.10 127 324 5.9E-32 T 30-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 PBC2_209 aeef31d1d434544e9625bff47f73b7dc 325 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 27 103 7.6E-8 T 30-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 PBC2_209 aeef31d1d434544e9625bff47f73b7dc 325 SUPERFAMILY SSF56349 26 316 3.83E-34 T 30-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 PBC2_209 aeef31d1d434544e9625bff47f73b7dc 325 Gene3D G3DSA:1.10.150.130 15 115 6.6E-11 T 30-10-2018 IPR010998 Integrase/recombinase, N-terminal PBC2_209 aeef31d1d434544e9625bff47f73b7dc 325 Pfam PF00589 Phage integrase family 136 314 2.6E-22 T 30-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 PBC2_200 f43650462351f2dae7714bf3219495f7 647 SUPERFAMILY SSF49785 131 218 3.4E-6 T 30-10-2018 IPR008979 Galactose-binding-like domain superfamily PBC2_200 f43650462351f2dae7714bf3219495f7 647 Gene3D G3DSA:2.60.120.260 288 443 8.6E-14 T 30-10-2018 IPR008979 Galactose-binding-like domain superfamily PBC2_200 f43650462351f2dae7714bf3219495f7 647 Gene3D G3DSA:2.60.120.260 86 222 1.7E-9 T 30-10-2018 IPR008979 Galactose-binding-like domain superfamily PBC2_052 c50939808e4f12ca99e3f99d3fc8ce08 228 Pfam PF04973 Nicotinamide mononucleotide transporter 34 220 6.8E-44 T 30-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 PBC2_052 c50939808e4f12ca99e3f99d3fc8ce08 228 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 34 224 3.0E-50 T 30-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 PBC2_020 d665e70286f4f635d7581b62ec0e9f5b 267 Pfam PF00069 Protein kinase domain 45 188 1.3E-6 T 30-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 PBC2_020 d665e70286f4f635d7581b62ec0e9f5b 267 SUPERFAMILY SSF56112 46 188 6.61E-12 T 30-10-2018 IPR011009 Protein kinase-like domain superfamily PBC2_020 d665e70286f4f635d7581b62ec0e9f5b 267 Gene3D G3DSA:1.10.510.10 17 211 7.2E-8 T 30-10-2018 PBC2_245 da9db826ddadf6d6f9580684430996a8 240 Pfam PF01551 Peptidase family M23 27 125 9.0E-20 T 30-10-2018 IPR016047 Peptidase M23 PBC2_245 da9db826ddadf6d6f9580684430996a8 240 Gene3D G3DSA:2.70.70.10 2 130 5.7E-26 T 30-10-2018 IPR011055 Duplicated hybrid motif PBC2_245 da9db826ddadf6d6f9580684430996a8 240 SUPERFAMILY SSF51261 10 129 1.44E-24 T 30-10-2018 IPR011055 Duplicated hybrid motif PBC2_129 034eb63e9703f48c3154b3926df6c954 141 Pfam PF07866 Protein of unknown function (DUF1653) 2 108 2.3E-5 T 30-10-2018 IPR023387 DUF1653-like domain PBC2_206 904663bfcce6d2a5b94fa7a30b226175 486 Gene3D G3DSA:2.30.30.40 318 385 1.0E-14 T 30-10-2018 PBC2_206 904663bfcce6d2a5b94fa7a30b226175 486 SMART SM00287 314 384 0.002 T 30-10-2018 IPR003646 SH3-like domain, bacterial-type PBC2_206 904663bfcce6d2a5b94fa7a30b226175 486 Pfam PF08239 Bacterial SH3 domain 326 381 3.5E-13 T 30-10-2018 IPR003646 SH3-like domain, bacterial-type PBC2_081 bd1c59d898e0c42e4429c9ac120ef027 364 Pfam PF13479 AAA domain 19 244 1.6E-24 T 30-10-2018 PBC2_188 43afde43a8214684beb1aadd17b3df98 188 SUPERFAMILY SSF53098 9 170 2.05E-17 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily PBC2_188 43afde43a8214684beb1aadd17b3df98 188 Gene3D G3DSA:3.30.420.10 7 174 1.7E-27 T 30-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 PBC2_188 43afde43a8214684beb1aadd17b3df98 188 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 72 88 5.5E-5 T 30-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 PBC2_188 43afde43a8214684beb1aadd17b3df98 188 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 156 168 5.5E-5 T 30-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 PBC2_188 43afde43a8214684beb1aadd17b3df98 188 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 8 21 5.5E-5 T 30-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 PBC2_188 43afde43a8214684beb1aadd17b3df98 188 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 53 167 5.7E-9 T 30-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 PBC2_083 048486eccc12e2b44636672a2e76f98d 176 Pfam PF13238 AAA domain 3 122 4.3E-8 T 30-10-2018 PBC2_083 048486eccc12e2b44636672a2e76f98d 176 SUPERFAMILY SSF52540 1 157 9.02E-22 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase PBC2_083 048486eccc12e2b44636672a2e76f98d 176 Gene3D G3DSA:3.40.50.300 1 172 1.4E-41 T 30-10-2018 PBC2_181 cf74d0351767bc5138d65cfe30b3836d 124 Gene3D G3DSA:3.90.226.10 1 121 1.1E-19 T 30-10-2018 PBC2_181 cf74d0351767bc5138d65cfe30b3836d 124 Pfam PF00574 Clp protease 4 110 2.7E-9 T 30-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA PBC2_181 cf74d0351767bc5138d65cfe30b3836d 124 SUPERFAMILY SSF52096 4 113 8.53E-17 T 30-10-2018 IPR029045 ClpP/crotonase-like domain superfamily PBC2_090 1c56625807e1913c781033bb9f03555d 562 Gene3D G3DSA:3.90.1640.30 43 320 1.3E-58 T 30-10-2018 PBC2_090 1c56625807e1913c781033bb9f03555d 562 Pfam PF01368 DHH family 69 212 3.7E-6 T 30-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 PBC2_090 1c56625807e1913c781033bb9f03555d 562 Gene3D G3DSA:3.10.310.30 321 437 2.3E-17 T 30-10-2018 PBC2_090 1c56625807e1913c781033bb9f03555d 562 SUPERFAMILY SSF64182 43 437 3.53E-71 T 30-10-2018 IPR038763 DHH phosphoesterase superfamily PBC2_153 c61fe41b1fe7818f79dca09a980a8d58 181 Pfam PF00226 DnaJ domain 132 172 1.2E-9 T 30-10-2018 IPR001623 DnaJ domain PBC2_153 c61fe41b1fe7818f79dca09a980a8d58 181 Gene3D G3DSA:1.10.287.110 119 180 7.9E-14 T 30-10-2018 IPR036869 Chaperone J-domain superfamily PBC2_153 c61fe41b1fe7818f79dca09a980a8d58 181 SUPERFAMILY SSF46565 132 176 7.59E-14 T 30-10-2018 IPR036869 Chaperone J-domain superfamily PBC2_153 c61fe41b1fe7818f79dca09a980a8d58 181 PRINTS PR00625 DnaJ domain signature 149 164 5.6E-8 T 30-10-2018 IPR001623 DnaJ domain PBC2_153 c61fe41b1fe7818f79dca09a980a8d58 181 PRINTS PR00625 DnaJ domain signature 131 149 5.6E-8 T 30-10-2018 IPR001623 DnaJ domain PBC2_161 d7d599bbad2b65f9961ed316a08485c2 435 Gene3D G3DSA:2.40.50.140 345 427 1.1E-16 T 30-10-2018 PBC2_161 d7d599bbad2b65f9961ed316a08485c2 435 SUPERFAMILY SSF50249 308 423 3.94E-22 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold PBC2_161 d7d599bbad2b65f9961ed316a08485c2 435 SUPERFAMILY SSF56091 139 334 1.53E-28 T 30-10-2018 PBC2_161 d7d599bbad2b65f9961ed316a08485c2 435 Pfam PF01068 ATP dependent DNA ligase domain 142 334 2.8E-21 T 30-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 PBC2_161 d7d599bbad2b65f9961ed316a08485c2 435 Gene3D G3DSA:3.30.470.30 139 334 1.9E-20 T 30-10-2018 PBC2_161 d7d599bbad2b65f9961ed316a08485c2 435 Pfam PF14743 DNA ligase OB-like domain 352 423 4.1E-13 T 30-10-2018 IPR029319 DNA ligase, OB-like domain PBC2_199 406aec887a4fefc41d182511532a8a79 591 SUPERFAMILY SSF49265 292 370 8.83E-9 T 30-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 PBC2_199 406aec887a4fefc41d182511532a8a79 591 Gene3D G3DSA:2.60.40.10 292 381 7.3E-7 T 30-10-2018 IPR013783 Immunoglobulin-like fold PBC2_076 18e7b7744ee7ed13e4360b4d66811c25 332 SUPERFAMILY SSF56349 24 270 2.12E-15 T 30-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 PBC2_076 18e7b7744ee7ed13e4360b4d66811c25 332 Gene3D G3DSA:1.10.443.10 106 314 7.7E-9 T 30-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 PBC2_202 e73e5423773064016e14445f2e6f8d1e 983 Pfam PF02018 Carbohydrate binding domain 62 196 5.8E-7 T 30-10-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 PBC2_202 e73e5423773064016e14445f2e6f8d1e 983 SUPERFAMILY SSF49785 60 194 1.67E-6 T 30-10-2018 IPR008979 Galactose-binding-like domain superfamily PBC2_202 e73e5423773064016e14445f2e6f8d1e 983 Gene3D G3DSA:2.60.120.260 59 203 1.4E-9 T 30-10-2018 IPR008979 Galactose-binding-like domain superfamily PBC2_127 e46cafafac66c94701d2ebfd8adb7eb2 276 Pfam PF01145 SPFH domain / Band 7 family 29 208 2.6E-23 T 30-10-2018 IPR001107 Band 7 domain PBC2_127 e46cafafac66c94701d2ebfd8adb7eb2 276 SUPERFAMILY SSF117892 67 196 5.1E-8 T 30-10-2018 IPR036013 Band 7/SPFH domain superfamily PBC2_208 a9bdc1dcf00d464aeab7aa294fea7acb 2304 Pfam PF10145 Phage-related minor tail protein 690 888 1.5E-27 T 30-10-2018 IPR010090 Phage tail tape measure protein PBC2_208 a9bdc1dcf00d464aeab7aa294fea7acb 2304 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 648 985 2.7E-42 T 30-10-2018 IPR010090 Phage tail tape measure protein PBC2_223 9e70dc1607441e101dd0f0b009604f57 562 Gene3D G3DSA:3.40.50.300 2 227 2.8E-20 T 30-10-2018 PBC2_080 49fc0abdf49cb836ec0ab698e00a525b 178 Gene3D G3DSA:3.90.75.20 5 124 2.2E-34 T 30-10-2018 PBC2_080 49fc0abdf49cb836ec0ab698e00a525b 178 SUPERFAMILY SSF54060 6 122 6.71E-27 T 30-10-2018 PBC2_080 49fc0abdf49cb836ec0ab698e00a525b 178 Pfam PF13392 HNH endonuclease 71 114 2.8E-11 T 30-10-2018 IPR003615 HNH nuclease PBC2_080 49fc0abdf49cb836ec0ab698e00a525b 178 Pfam PF07463 NUMOD4 motif 6 63 3.0E-12 T 30-10-2018 IPR010902 NUMOD4 GO:0016788 PBC2_195 7980839130e1fdd67be96e17251cb038 111 Pfam PF09682 Bacteriophage holin of superfamily 6 (Holin_LLH) 8 102 2.9E-19 T 30-10-2018 IPR010026 Phage holin, LL-H family PBC2_204 f03b639f61cd96261ced72035c22a95a 899 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 56 262 1.2E-10 T 30-10-2018 IPR007119 Phage minor structural protein, N-terminal domain PBC2_204 f03b639f61cd96261ced72035c22a95a 899 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 413 498 2.3E-12 T 30-10-2018 IPR007119 Phage minor structural protein, N-terminal domain PBC2_149 c808aa1c760e75a6c10557e9b281849f 122 Pfam PF10686 Protein of unknown function (DUF2493) 2 67 4.3E-14 T 30-10-2018 IPR019627 Mycobacteriophage D29, Gp61 PBC2_149 c808aa1c760e75a6c10557e9b281849f 122 SUPERFAMILY SSF102405 10 121 2.49E-7 T 30-10-2018 PBC2_069 77288d73594e78048095f89cf2e18bdb 161 Pfam PF10263 SprT-like family 25 88 3.4E-6 T 30-10-2018 IPR006640 SprT-like PBC2_069 77288d73594e78048095f89cf2e18bdb 161 SMART SM00731 5 155 5.4E-6 T 30-10-2018 IPR006640 SprT-like PBC2_003 87d83ff03ea7b187f9b6fc093cf0a828 126 Pfam PF13876 Phage protein (N4 Gp49/phage Sf6 gene 66) family 14 81 2.1E-15 T 30-10-2018 IPR025915 Phage protein (N4 Gp49/phage Sf6 gene 66) family PBC2_183 e4ac954a22239700a7e530966afc7836 188 SUPERFAMILY SSF109604 3 145 2.2E-27 T 30-10-2018 PBC2_183 e4ac954a22239700a7e530966afc7836 188 Gene3D G3DSA:1.10.3210.10 1 174 1.9E-40 T 30-10-2018 PBC2_089 6608daab54335c73e7b9eb8d5d416cbd 133 Gene3D G3DSA:1.10.1220.10 36 122 3.0E-6 T 30-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 PBC2_227 11ea7ee1287b3a6d339419a63da0753c 259 Pfam PF01844 HNH endonuclease 187 228 2.1E-6 T 30-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 PBC2_227 11ea7ee1287b3a6d339419a63da0753c 259 SMART SM00507 174 228 2.1E-5 T 30-10-2018 IPR003615 HNH nuclease PBC2_243 d4074a583cdd9112125890507e41a3ca 935 SUPERFAMILY SSF52540 443 810 7.34E-10 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase PBC2_123 a1d4922210a4f85cbeb80125d0e4364a 253 Pfam PF10127 Predicted nucleotidyltransferase 8 164 1.9E-6 T 30-10-2018 IPR018775 Nucleotidyltransferase, predicted PBC2_205 349634f113ddde5917f5d79d60925101 256 Pfam PF05709 Phage tail protein 41 255 3.4E-10 T 30-10-2018 IPR008841 Siphovirus-type tail component