locus-tag	class	description
QCM8_105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
QCM8_110	COG0420	3'-5' exonuclease activity
QCM8_111	COG0419	ATPase involved in DNA repair
QCM8_124	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
QCM8_127	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
QCM8_144	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
QCM8_197	COG1191	sigma factor activity
QCM8_29	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
QCM8_33	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
QCM8_37	COG1702	phosphate starvation-inducible protein PhoH
QCM8_76	COG1388	LysM domain
QCM8_76	COG3584	3D domain protein
QCM8_83	COG4193	domain, Protein
QCM8_83	COG5263	repeat protein
QCM8_84	COG0791	NLP P60 protein
QCM8_84	COG3883	PFAM NLP P60 protein