SBP8a_71 a13f7658d929b146ed0617a335114ce4 599 Pfam PF05876 Phage terminase large subunit (GpA) 63 426 4.1E-25 T 30-10-2018 IPR008866 Bacteriophage lambda, GpA SBP8a_71 a13f7658d929b146ed0617a335114ce4 599 Gene3D G3DSA:3.40.50.300 47 231 1.3E-11 T 30-10-2018 SBP8a_181 1dbd46266e04cc28db4602324cc1d15f 97 Pfam PF04688 SPP1 phage holin 16 88 9.6E-13 T 30-10-2018 IPR006479 Holin SBP8a_181 1dbd46266e04cc28db4602324cc1d15f 97 ProDom PD008023 HOLIN TRANSMEMBRANE MEMBRANE PROPHAGE FAMILY BHLB SPP1 5'REGION HOLIN ORF050 19 84 4.0E-4 T 30-10-2018 IPR006479 Holin SBP8a_56 eabaac3d4c7a04fe009afa67fa8a1f71 220 Pfam PF13238 AAA domain 19 181 6.2E-10 T 30-10-2018 SBP8a_56 eabaac3d4c7a04fe009afa67fa8a1f71 220 SUPERFAMILY SSF52540 18 214 5.13E-12 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SBP8a_56 eabaac3d4c7a04fe009afa67fa8a1f71 220 Gene3D G3DSA:3.40.50.300 19 214 3.9E-25 T 30-10-2018 SBP8a_149 a4fe4c8ab68f650525bc7e616e87968d 108 Gene3D G3DSA:4.10.520.10 5 99 1.2E-6 T 30-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 SBP8a_149 a4fe4c8ab68f650525bc7e616e87968d 108 Pfam PF00216 Bacterial DNA-binding protein 6 90 3.9E-10 T 30-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SBP8a_149 a4fe4c8ab68f650525bc7e616e87968d 108 SUPERFAMILY SSF47729 5 90 5.15E-10 T 30-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 SBP8a_135 8bd10ecf997c5b70080a09e7f90bcf36 784 SUPERFAMILY SSF48168 37 243 2.49E-32 T 30-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SBP8a_135 8bd10ecf997c5b70080a09e7f90bcf36 784 PRINTS PR01183 Ribonucleotide reductase large chain signature 321 340 2.3E-19 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SBP8a_135 8bd10ecf997c5b70080a09e7f90bcf36 784 PRINTS PR01183 Ribonucleotide reductase large chain signature 526 549 2.3E-19 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SBP8a_135 8bd10ecf997c5b70080a09e7f90bcf36 784 PRINTS PR01183 Ribonucleotide reductase large chain signature 472 483 2.3E-19 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SBP8a_135 8bd10ecf997c5b70080a09e7f90bcf36 784 PRINTS PR01183 Ribonucleotide reductase large chain signature 652 679 2.3E-19 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SBP8a_135 8bd10ecf997c5b70080a09e7f90bcf36 784 PRINTS PR01183 Ribonucleotide reductase large chain signature 564 586 2.3E-19 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SBP8a_135 8bd10ecf997c5b70080a09e7f90bcf36 784 SUPERFAMILY SSF51998 245 772 1.59E-115 T 30-10-2018 SBP8a_135 8bd10ecf997c5b70080a09e7f90bcf36 784 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 169 770 1.2E-121 T 30-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SBP8a_135 8bd10ecf997c5b70080a09e7f90bcf36 784 Gene3D G3DSA:1.10.1650.20 364 434 6.7E-152 T 30-10-2018 SBP8a_135 8bd10ecf997c5b70080a09e7f90bcf36 784 Gene3D G3DSA:3.20.70.20 231 768 6.7E-152 T 30-10-2018 SBP8a_135 8bd10ecf997c5b70080a09e7f90bcf36 784 Pfam PF02867 Ribonucleotide reductase, barrel domain 246 767 2.0E-99 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SBP8a_135 8bd10ecf997c5b70080a09e7f90bcf36 784 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 166 243 2.3E-8 T 30-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SBP8a_138 703faa4a6f93544da8ff25f65bf88caf 369 Gene3D G3DSA:1.10.620.20 31 332 1.7E-68 T 30-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 SBP8a_138 703faa4a6f93544da8ff25f65bf88caf 369 SUPERFAMILY SSF47240 33 332 5.73E-56 T 30-10-2018 IPR009078 Ferritin-like superfamily SBP8a_138 703faa4a6f93544da8ff25f65bf88caf 369 Pfam PF00268 Ribonucleotide reductase, small chain 42 322 5.9E-44 T 30-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SBP8a_67 4ce8fc1240ced60096df63abebe0d3c4 492 SUPERFAMILY SSF51690 183 490 1.68E-31 T 30-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SBP8a_67 4ce8fc1240ced60096df63abebe0d3c4 492 PIRSF PIRSF005943 1 492 8.9E-157 T 30-10-2018 IPR016471 Nicotinamide phosphoribosyl transferase Reactome: R-HSA-1368108|Reactome: R-HSA-197264 SBP8a_67 4ce8fc1240ced60096df63abebe0d3c4 492 Gene3D G3DSA:3.20.20.70 150 430 2.7E-89 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SBP8a_67 4ce8fc1240ced60096df63abebe0d3c4 492 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 186 474 7.4E-42 T 30-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SBP8a_69 ddfd9502f66b05b617615365e534436b 277 Pfam PF08460 Bacterial SH3 domain 200 255 2.6E-7 T 30-10-2018 IPR003646 SH3-like domain, bacterial-type SBP8a_69 ddfd9502f66b05b617615365e534436b 277 SUPERFAMILY SSF55846 21 157 3.84E-40 T 30-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SBP8a_69 ddfd9502f66b05b617615365e534436b 277 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 25 142 1.5E-17 T 30-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SBP8a_69 ddfd9502f66b05b617615365e534436b 277 Gene3D G3DSA:3.40.80.10 16 163 2.3E-39 T 30-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SBP8a_69 ddfd9502f66b05b617615365e534436b 277 SMART SM00644 10 151 5.2E-32 T 30-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SBP8a_69 ddfd9502f66b05b617615365e534436b 277 SMART SM00287 201 267 8.4E-13 T 30-10-2018 IPR003646 SH3-like domain, bacterial-type SBP8a_69 ddfd9502f66b05b617615365e534436b 277 Gene3D G3DSA:2.30.30.410 164 277 2.6E-12 T 30-10-2018 SBP8a_234 474a569d02aa9e43e19120051b3f26d7 246 Pfam PF12706 Beta-lactamase superfamily domain 29 219 6.7E-15 T 30-10-2018 IPR001279 Metallo-beta-lactamase SBP8a_234 474a569d02aa9e43e19120051b3f26d7 246 Gene3D G3DSA:3.60.15.10 4 241 2.2E-25 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like SBP8a_234 474a569d02aa9e43e19120051b3f26d7 246 SUPERFAMILY SSF56281 2 226 2.75E-28 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like SBP8a_234 474a569d02aa9e43e19120051b3f26d7 246 SMART SM00849 17 219 0.001 T 30-10-2018 IPR001279 Metallo-beta-lactamase SBP8a_139 c81958f1fc4bbe96dba02a8be5850c86 146 Gene3D G3DSA:3.40.50.360 1 144 2.8E-14 T 30-10-2018 IPR029039 Flavoprotein-like superfamily SBP8a_139 c81958f1fc4bbe96dba02a8be5850c86 146 Pfam PF00258 Flavodoxin 6 112 2.0E-7 T 30-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 SBP8a_139 c81958f1fc4bbe96dba02a8be5850c86 146 SUPERFAMILY SSF52218 1 137 1.08E-13 T 30-10-2018 IPR029039 Flavoprotein-like superfamily SBP8a_127 0f8e13e1fa3a92f8adc672a4fdc21977 358 SUPERFAMILY SSF57783 8 76 1.87E-13 T 30-10-2018 SBP8a_127 0f8e13e1fa3a92f8adc672a4fdc21977 358 Gene3D G3DSA:3.40.1360.10 230 346 2.4E-7 T 30-10-2018 SBP8a_127 0f8e13e1fa3a92f8adc672a4fdc21977 358 Gene3D G3DSA:3.90.580.10 2 83 9.7E-11 T 30-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 SBP8a_127 0f8e13e1fa3a92f8adc672a4fdc21977 358 Pfam PF12760 Transposase zinc-ribbon domain 21 51 6.9E-7 T 30-10-2018 IPR024442 Transposase, zinc-ribbon SBP8a_127 0f8e13e1fa3a92f8adc672a4fdc21977 358 SUPERFAMILY SSF56731 140 344 3.92E-13 T 30-10-2018 SBP8a_226 68e4d4c684b6afdadccd0d8d78936d22 292 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 231 9.4E-15 T 30-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 SBP8a_226 68e4d4c684b6afdadccd0d8d78936d22 292 Pfam PF04545 Sigma-70, region 4 183 231 5.2E-7 T 30-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 SBP8a_226 68e4d4c684b6afdadccd0d8d78936d22 292 Pfam PF04542 Sigma-70 region 2 23 90 1.7E-7 T 30-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 SBP8a_226 68e4d4c684b6afdadccd0d8d78936d22 292 Gene3D G3DSA:1.10.1740.10 2 89 8.6E-6 T 30-10-2018 SBP8a_226 68e4d4c684b6afdadccd0d8d78936d22 292 SUPERFAMILY SSF88659 161 234 5.42E-11 T 30-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like SBP8a_226 68e4d4c684b6afdadccd0d8d78936d22 292 Gene3D G3DSA:1.20.140.160 111 234 5.7E-14 T 30-10-2018 SBP8a_226 68e4d4c684b6afdadccd0d8d78936d22 292 SUPERFAMILY SSF88946 5 93 1.54E-11 T 30-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 SBP8a_98 07450704a60c2c32a94a8869565840c0 240 SUPERFAMILY SSF50685 169 220 2.02E-8 T 30-10-2018 IPR036908 RlpA-like domain superfamily SBP8a_98 07450704a60c2c32a94a8869565840c0 240 Gene3D G3DSA:2.40.40.10 125 223 4.0E-6 T 30-10-2018 IPR036908 RlpA-like domain superfamily SBP8a_98 07450704a60c2c32a94a8869565840c0 240 Pfam PF06725 3D domain 180 240 1.6E-20 T 30-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 SBP8a_98 07450704a60c2c32a94a8869565840c0 240 SUPERFAMILY SSF158634 70 120 2.09E-5 T 30-10-2018 SBP8a_121 b61a71b0f49cb665ef4573cb9a33a18f 365 Pfam PF00149 Calcineurin-like phosphoesterase 4 215 2.1E-9 T 30-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SBP8a_121 b61a71b0f49cb665ef4573cb9a33a18f 365 Gene3D G3DSA:3.60.21.10 4 265 2.2E-34 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like SBP8a_121 b61a71b0f49cb665ef4573cb9a33a18f 365 SUPERFAMILY SSF56300 5 304 4.75E-27 T 30-10-2018 SBP8a_202 6b46501a450130b095be25d5772bea54 99 SUPERFAMILY SSF101386 19 97 3.6E-10 T 30-10-2018 SBP8a_202 6b46501a450130b095be25d5772bea54 99 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 19 93 4.8E-5 T 30-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core SBP8a_202 6b46501a450130b095be25d5772bea54 99 Gene3D G3DSA:1.10.287.1080 8 99 1.8E-12 T 30-10-2018 SBP8a_175 711c8ede776b20612c82389b43b518b1 415 Gene3D G3DSA:3.40.50.300 41 356 1.1E-62 T 30-10-2018 SBP8a_175 711c8ede776b20612c82389b43b518b1 415 PRINTS PR00142 RecA protein signature 267 296 8.8E-8 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SBP8a_175 711c8ede776b20612c82389b43b518b1 415 PRINTS PR00142 RecA protein signature 99 128 8.8E-8 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SBP8a_175 711c8ede776b20612c82389b43b518b1 415 PRINTS PR00142 RecA protein signature 230 258 8.8E-8 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SBP8a_175 711c8ede776b20612c82389b43b518b1 415 Pfam PF00154 recA bacterial DNA recombination protein 51 291 7.3E-32 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SBP8a_175 711c8ede776b20612c82389b43b518b1 415 SUPERFAMILY SSF52540 40 291 1.61E-24 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SBP8a_102 84e0db46ca245314d7f577f547b34bf0 725 SUPERFAMILY SSF54001 582 721 9.81E-18 T 30-10-2018 IPR038765 Papain-like cysteine peptidase superfamily SBP8a_102 84e0db46ca245314d7f577f547b34bf0 725 Pfam PF00877 NlpC/P60 family 596 718 1.3E-17 T 30-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain SBP8a_102 84e0db46ca245314d7f577f547b34bf0 725 Gene3D G3DSA:3.90.1720.10 539 719 9.3E-22 T 30-10-2018 SBP8a_113 86bfa5fcc8ed80d565fd0f9c11f1cbad 1203 Pfam PF16075 Domain of unknown function (DUF4815) 11 634 2.5E-125 T 30-10-2018 IPR032096 Domain of unknown function DUF4815 SBP8a_129 bbc5aed2631144dbf6d61e304fcaef39 270 SUPERFAMILY SSF51283 12 105 8.64E-14 T 30-10-2018 IPR036157 dUTPase-like superfamily SBP8a_129 bbc5aed2631144dbf6d61e304fcaef39 270 SUPERFAMILY SSF51283 217 269 3.27E-8 T 30-10-2018 IPR036157 dUTPase-like superfamily SBP8a_129 bbc5aed2631144dbf6d61e304fcaef39 270 Pfam PF00692 dUTPase 33 107 7.4E-5 T 30-10-2018 IPR029054 dUTPase-like SBP8a_53 2aaa7d2295c2a85f5d18f08e8907b905 166 SUPERFAMILY SSF53597 2 165 1.54E-46 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 SBP8a_53 2aaa7d2295c2a85f5d18f08e8907b905 166 Pfam PF00186 Dihydrofolate reductase 3 164 1.2E-48 T 30-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SBP8a_53 2aaa7d2295c2a85f5d18f08e8907b905 166 Gene3D G3DSA:3.40.430.10 1 166 6.1E-49 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 SBP8a_53 2aaa7d2295c2a85f5d18f08e8907b905 166 PRINTS PR00070 Dihydrofolate reductase signature 41 52 1.6E-7 T 30-10-2018 SBP8a_53 2aaa7d2295c2a85f5d18f08e8907b905 166 PRINTS PR00070 Dihydrofolate reductase signature 94 108 1.6E-7 T 30-10-2018 SBP8a_53 2aaa7d2295c2a85f5d18f08e8907b905 166 PRINTS PR00070 Dihydrofolate reductase signature 28 36 1.6E-7 T 30-10-2018 SBP8a_133 b74d988eb5ae55841b98fe7ab44f468b 187 ProDom PD927567 D14 PHAGE GP54 SPO1 GENE ORF78 ORF063 ORF064 11 135 2.0E-20 T 30-10-2018 SBP8a_115 dc310e74e4612429e0cfeecc16f7ccf8 589 SUPERFAMILY SSF52540 19 384 2.0E-18 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SBP8a_115 dc310e74e4612429e0cfeecc16f7ccf8 589 Gene3D G3DSA:3.40.50.300 276 387 3.3E-9 T 30-10-2018 SBP8a_115 dc310e74e4612429e0cfeecc16f7ccf8 589 Gene3D G3DSA:3.40.50.300 100 233 4.1E-10 T 30-10-2018 SBP8a_115 dc310e74e4612429e0cfeecc16f7ccf8 589 Pfam PF04851 Type III restriction enzyme, res subunit 119 366 9.3E-11 T 30-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SBP8a_115 dc310e74e4612429e0cfeecc16f7ccf8 589 Gene3D G3DSA:3.40.50.300 404 589 2.1E-33 T 30-10-2018 SBP8a_115 dc310e74e4612429e0cfeecc16f7ccf8 589 Pfam PF00271 Helicase conserved C-terminal domain 454 545 1.8E-13 T 30-10-2018 IPR001650 Helicase, C-terminal SBP8a_115 dc310e74e4612429e0cfeecc16f7ccf8 589 SMART SM00490 465 546 2.6E-16 T 30-10-2018 IPR001650 Helicase, C-terminal SBP8a_115 dc310e74e4612429e0cfeecc16f7ccf8 589 SUPERFAMILY SSF52540 321 559 8.49E-25 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SBP8a_59 730864aee808740461924e08bd5d46df 300 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 18 295 7.7E-87 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SBP8a_59 730864aee808740461924e08bd5d46df 300 Hamap MF_00008 Thymidylate synthase [thyA]. 13 295 30.83 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SBP8a_59 730864aee808740461924e08bd5d46df 300 SUPERFAMILY SSF55831 5 295 4.19E-96 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SBP8a_59 730864aee808740461924e08bd5d46df 300 PRINTS PR00108 Thymidylate synthase family signature 145 164 3.4E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SBP8a_59 730864aee808740461924e08bd5d46df 300 PRINTS PR00108 Thymidylate synthase family signature 171 186 3.4E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SBP8a_59 730864aee808740461924e08bd5d46df 300 PRINTS PR00108 Thymidylate synthase family signature 190 216 3.4E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SBP8a_59 730864aee808740461924e08bd5d46df 300 PRINTS PR00108 Thymidylate synthase family signature 54 75 3.4E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SBP8a_59 730864aee808740461924e08bd5d46df 300 PRINTS PR00108 Thymidylate synthase family signature 228 245 3.4E-32 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SBP8a_59 730864aee808740461924e08bd5d46df 300 Pfam PF00303 Thymidylate synthase 19 295 6.1E-90 T 30-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SBP8a_59 730864aee808740461924e08bd5d46df 300 Gene3D G3DSA:3.30.572.10 5 295 4.4E-100 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SBP8a_187 528fecdb11d728bd172245858b9548ba 425 Gene3D G3DSA:3.60.21.10 161 388 1.1E-5 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like SBP8a_187 528fecdb11d728bd172245858b9548ba 425 SUPERFAMILY SSF56300 162 388 3.35E-10 T 30-10-2018 SBP8a_110 9e5da6f8c603d0b53b2c6d436d4bda16 250 Gene3D G3DSA:3.10.450.40 126 243 1.0E-10 T 30-10-2018 SBP8a_110 9e5da6f8c603d0b53b2c6d436d4bda16 250 SUPERFAMILY SSF160719 139 237 6.02E-14 T 30-10-2018 SBP8a_110 9e5da6f8c603d0b53b2c6d436d4bda16 250 Pfam PF10934 Protein of unknown function (DUF2634) 136 224 1.7E-8 T 30-10-2018 IPR020288 Protein of unknown function DUF2634 SBP8a_124 85908aacc51ec9253fc64ca1d1887179 629 SUPERFAMILY SSF52540 362 621 4.69E-20 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SBP8a_124 85908aacc51ec9253fc64ca1d1887179 629 SUPERFAMILY SSF75712 277 357 9.29E-7 T 30-10-2018 SBP8a_124 85908aacc51ec9253fc64ca1d1887179 629 SUPERFAMILY SSF52540 1 615 1.38E-14 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SBP8a_124 85908aacc51ec9253fc64ca1d1887179 629 Gene3D G3DSA:3.40.50.300 1 320 6.0E-27 T 30-10-2018 SBP8a_124 85908aacc51ec9253fc64ca1d1887179 629 Gene3D G3DSA:3.40.50.300 331 625 3.9E-29 T 30-10-2018 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 SUPERFAMILY SSF53098 189 331 1.25E-16 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 Pfam PF01612 3'-5' exonuclease 193 350 4.5E-12 T 30-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 Gene3D G3DSA:3.40.470.10 25 179 1.3E-12 T 30-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 SMART SM00482 723 929 3.6E-38 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 PRINTS PR00868 DNA-polymerase family A (pol I) signature 685 707 1.2E-31 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 PRINTS PR00868 DNA-polymerase family A (pol I) signature 791 816 1.2E-31 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 PRINTS PR00868 DNA-polymerase family A (pol I) signature 737 760 1.2E-31 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 PRINTS PR00868 DNA-polymerase family A (pol I) signature 767 780 1.2E-31 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 PRINTS PR00868 DNA-polymerase family A (pol I) signature 912 925 1.2E-31 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 PRINTS PR00868 DNA-polymerase family A (pol I) signature 850 861 1.2E-31 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 PRINTS PR00868 DNA-polymerase family A (pol I) signature 882 898 1.2E-31 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 PRINTS PR00868 DNA-polymerase family A (pol I) signature 828 839 1.2E-31 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 Gene3D G3DSA:3.30.70.370 694 969 9.2E-64 T 30-10-2018 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 Pfam PF00476 DNA polymerase family A 573 971 7.6E-69 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 Gene3D G3DSA:1.10.150.20 746 889 9.2E-64 T 30-10-2018 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 SUPERFAMILY SSF52141 31 176 2.03E-5 T 30-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SBP8a_156 01fa997131d4e3d1db6a7d9a34602079 1033 SUPERFAMILY SSF56672 493 975 1.89E-89 T 30-10-2018 SBP8a_84 11563040a28a69a1ca7f8a7c8704c233 268 Pfam PF04586 Caudovirus prohead serine protease 38 175 1.2E-4 T 30-10-2018 IPR006433 Prohead protease SBP8a_142 a6d9312273c66fe181cb4397a2c81aeb 89 Gene3D G3DSA:3.40.30.10 2 87 1.6E-6 T 30-10-2018 SBP8a_142 a6d9312273c66fe181cb4397a2c81aeb 89 SUPERFAMILY SSF52833 4 61 7.29E-8 T 30-10-2018 IPR036249 Thioredoxin-like superfamily SBP8a_82 cd3ff595d3d8d6e01c9681ccf3f54034 563 Pfam PF04860 Phage portal protein 162 462 3.0E-21 T 30-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein SBP8a_55 1be04b635f97436452c0526144ab7081 101 SUPERFAMILY SSF57997 5 100 2.48E-7 T 30-10-2018 SBP8a_55 1be04b635f97436452c0526144ab7081 101 Gene3D G3DSA:1.20.5.340 1 101 3.2E-8 T 30-10-2018 SBP8a_101 6a3a097194634956fd38227047b60b27 1269 Gene3D G3DSA:1.10.530.10 1095 1215 1.4E-13 T 30-10-2018 SBP8a_101 6a3a097194634956fd38227047b60b27 1269 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 1104 1213 2.1E-14 T 30-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SBP8a_101 6a3a097194634956fd38227047b60b27 1269 SMART SM00047 1090 1229 3.5E-7 T 30-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SBP8a_68 0f21b8064fcb84196d3c006a95626b22 278 Gene3D G3DSA:3.40.50.2020 129 277 2.9E-14 T 30-10-2018 SBP8a_68 0f21b8064fcb84196d3c006a95626b22 278 SUPERFAMILY SSF53271 152 264 9.44E-9 T 30-10-2018 IPR029057 Phosphoribosyltransferase-like SBP8a_68 0f21b8064fcb84196d3c006a95626b22 278 SUPERFAMILY SSF53271 65 120 2.3E-5 T 30-10-2018 IPR029057 Phosphoribosyltransferase-like SBP8a_68 0f21b8064fcb84196d3c006a95626b22 278 Gene3D G3DSA:3.40.50.2020 2 128 2.6E-9 T 30-10-2018 SBP8a_119 7cc0c8550167c264fe89a5db39e9e4dc 492 SMART SM00382 191 414 2.8E-5 T 30-10-2018 IPR003593 AAA+ ATPase domain SBP8a_119 7cc0c8550167c264fe89a5db39e9e4dc 492 SUPERFAMILY SSF52540 172 415 3.03E-25 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SBP8a_119 7cc0c8550167c264fe89a5db39e9e4dc 492 Gene3D G3DSA:3.40.50.300 149 422 2.0E-40 T 30-10-2018 SBP8a_119 7cc0c8550167c264fe89a5db39e9e4dc 492 Pfam PF03796 DnaB-like helicase C terminal domain 174 361 7.5E-17 T 30-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 SBP8a_80 126018618de15fa2d83d2bf7baf9ed17 278 SUPERFAMILY SSF51126 15 204 4.71E-6 T 30-10-2018 IPR011050 Pectin lyase fold/virulence factor SBP8a_222 cb7682d25c1b867b8434cd877053b8b4 255 Gene3D G3DSA:1.10.10.60 111 155 2.7E-5 T 30-10-2018 SBP8a_222 cb7682d25c1b867b8434cd877053b8b4 255 Gene3D G3DSA:1.10.10.60 44 94 6.3E-5 T 30-10-2018 SBP8a_111 3547fa0eb41cbd915a3d4dd50c40ab6a 348 Pfam PF04865 Baseplate J-like protein 66 306 3.4E-34 T 30-10-2018 IPR006949 Baseplate protein J-like SBP8a_66 e03331f30479c36128ff287301a62d0b 136 Gene3D G3DSA:3.40.50.1000 22 133 7.1E-19 T 30-10-2018 IPR023214 HAD superfamily SBP8a_66 e03331f30479c36128ff287301a62d0b 136 SUPERFAMILY SSF56784 26 114 8.26E-13 T 30-10-2018 IPR036412 HAD-like superfamily