locus-tag	class	description
NATE_105	COG1388	LysM domain
NATE_105	COG3584	3D domain protein
NATE_106	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NATE_114	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NATE_116	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NATE_142	COG0187	DNA topoisomerase II activity
NATE_143	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NATE_146	COG1780	Probably involved in ribonucleotide reductase function
NATE_148	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NATE_149	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NATE_151	COG0756	dUTP diphosphatase activity
NATE_162	COG1234	tRNA 3'-trailer cleavage
NATE_170	COG1404	Belongs to the peptidase S8 family
NATE_175	COG0740	serine-type endopeptidase activity
NATE_193	COG0740	serine-type endopeptidase activity
NATE_194	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NATE_195	COG1435	thymidine kinase activity
NATE_197	COG0587	DNA-directed DNA polymerase activity
NATE_209	COG1388	LysM domain
NATE_209	COG3409	Peptidoglycan-binding domain 1 protein
NATE_209	COG5632	N-Acetylmuramoyl-L-alanine amidase
NATE_212	COG3209	COG3209 Rhs family protein
NATE_214	COG2433	Pfam Transposase IS66
NATE_216	COG0739	heme binding
NATE_216	COG0741	lytic transglycosylase activity
NATE_216	COG1196	nuclear chromosome segregation
NATE_217	COG0582	viral genome integration into host DNA
NATE_22	COG2195	Cleaves the N-terminal amino acid of tripeptides
NATE_259	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NATE_271	COG0739	heme binding
NATE_276	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NATE_93	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NATE_95	COG3091	SprT-like family