locus-tag	class	description
SKYWALKER_109	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SKYWALKER_11	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SKYWALKER_119	COG0740	serine-type endopeptidase activity
SKYWALKER_123	COG1404	Belongs to the peptidase S8 family
SKYWALKER_138	COG0194	GDP metabolic process
SKYWALKER_143	COG0756	dUTP diphosphatase activity
SKYWALKER_145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SKYWALKER_146	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SKYWALKER_148	COG1780	Probably involved in ribonucleotide reductase function
SKYWALKER_151	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SKYWALKER_152	COG0187	DNA topoisomerase II activity
SKYWALKER_16	COG0739	heme binding
SKYWALKER_176	COG0322	excinuclease ABC activity
SKYWALKER_186	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SKYWALKER_188	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SKYWALKER_197	COG3584	3D domain protein
SKYWALKER_197	COG1388	LysM domain
SKYWALKER_207	COG3091	SprT-like family
SKYWALKER_240	COG2195	Cleaves the N-terminal amino acid of tripeptides
SKYWALKER_28	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SKYWALKER_70	COG0582	viral genome integration into host DNA
SKYWALKER_71	COG0739	heme binding
SKYWALKER_71	COG0741	lytic transglycosylase activity
SKYWALKER_71	COG1196	nuclear chromosome segregation
SKYWALKER_74	COG2433	Pfam Transposase IS66
SKYWALKER_80	COG1388	LysM domain
SKYWALKER_80	COG3409	Peptidoglycan-binding domain 1 protein
SKYWALKER_80	COG5632	N-Acetylmuramoyl-L-alanine amidase
SKYWALKER_92	COG0587	DNA-directed DNA polymerase activity
SKYWALKER_94	COG1435	thymidine kinase activity
SKYWALKER_96	COG0740	serine-type endopeptidase activity
SKYWALKER_97	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis