locus-tag	class	description
vBBcoS136_00009	COG3091	SprT-like family
vBBcoS136_00036	COG2195	Cleaves the N-terminal amino acid of tripeptides
vBBcoS136_00076	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
vBBcoS136_00088	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
vBBcoS136_00095	COG0739	heme binding
vBBcoS136_00108	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
vBBcoS136_00143	COG4974	Belongs to the 'phage' integrase family
vBBcoS136_00144	COG0739	heme binding
vBBcoS136_00144	COG0741	lytic transglycosylase activity
vBBcoS136_00144	COG1196	nuclear chromosome segregation
vBBcoS136_00147	COG2433	Pfam Transposase IS66
vBBcoS136_00153	COG5632	N-Acetylmuramoyl-L-alanine amidase
vBBcoS136_00166	COG0587	DNA-directed DNA polymerase activity
vBBcoS136_00169	COG1435	thymidine kinase activity
vBBcoS136_00170	COG1435	thymidine kinase activity
vBBcoS136_00173	COG0740	serine-type endopeptidase activity
vBBcoS136_00175	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
vBBcoS136_00179	COG1610	YqeY-like protein
vBBcoS136_00182	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
vBBcoS136_00187	COG0740	serine-type endopeptidase activity
vBBcoS136_00196	COG0194	GDP metabolic process
vBBcoS136_00204	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
vBBcoS136_00206	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
vBBcoS136_00210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
vBBcoS136_00211	COG0187	DNA topoisomerase II activity
vBBcoS136_00235	COG0328	RNA-DNA hybrid ribonuclease activity
vBBcoS136_00243	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
vBBcoS136_00245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
vBBcoS136_00245	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
vBBcoS136_00247	COG0358	DNA primase activity
vBBcoS136_00250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
vBBcoS136_00251	COG3584	3D domain protein