locus-tag	class	description
C5Y82_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C5Y82_00010	COG0592	DNA-directed DNA polymerase activity
C5Y82_00015	COG2501	S4 domain
C5Y82_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C5Y82_00030	COG0187	DNA topoisomerase II activity
C5Y82_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C5Y82_00070	COG0517	IMP dehydrogenase activity
C5Y82_00070	COG0516	GMP reductase activity
C5Y82_00075	COG1686	Belongs to the peptidase S11 family
C5Y82_00080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5Y82_00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C5Y82_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C5Y82_00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C5Y82_00100	COG0840	transmembrane signaling receptor activity
C5Y82_00110	COG1428	Deoxynucleoside kinase
C5Y82_00115	COG1428	Deoxynucleoside kinase
C5Y82_00120	COG3858	chitin binding
C5Y82_00120	COG1388	LysM domain
C5Y82_00125	COG1335	isochorismatase
C5Y82_00130	COG0590	tRNA wobble adenosine to inosine editing
C5Y82_00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C5Y82_00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C5Y82_00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C5Y82_00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C5Y82_00200	COG3853	Toxic anion resistance protein (TelA)
C5Y82_00205	COG1982	Orn Lys Arg decarboxylase major
C5Y82_00210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C5Y82_00215	COG3870	Protein conserved in bacteria
C5Y82_00220	COG1728	Protein conserved in bacteria
C5Y82_00225	COG0470	DNA polymerase III
C5Y82_00230	COG1774	PSP1 C-terminal conserved region
C5Y82_00235	COG4467	Involved in initiation control of chromosome replication
C5Y82_00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C5Y82_00245	COG2827	Endonuclease containing a URI domain
C5Y82_00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C5Y82_00255	COG2002	toxin-antitoxin pair type II binding
C5Y82_00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5Y82_00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5Y82_00265	COG0084	hydrolase, TatD family'
C5Y82_00270	COG3583	domain protein
C5Y82_00270	COG3584	3D domain protein
C5Y82_00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C5Y82_00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C5Y82_00290	COG4466	Protein conserved in bacteria
C5Y82_00300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C5Y82_00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C5Y82_00310	COG0251	oxidation-reduction process
C5Y82_00315	COG2088	sporulation resulting in formation of a cellular spore
C5Y82_00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C5Y82_00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C5Y82_00335	COG0193	aminoacyl-tRNA hydrolase activity
C5Y82_00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C5Y82_00350	COG2002	toxin-antitoxin pair type II binding
C5Y82_00355	COG2244	polysaccharide biosynthetic process
C5Y82_00360	COG3956	TIGRFAM MazG family protein
C5Y82_00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C5Y82_00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C5Y82_00385	COG1098	S1 RNA binding domain
C5Y82_00400	COG2208	phosphoserine phosphatase activity
C5Y82_00405	COG2304	oxidoreductase activity
C5Y82_00410	COG0515	serine threonine protein kinase
C5Y82_00415	COG0037	tRNA processing
C5Y82_00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C5Y82_00430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C5Y82_00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C5Y82_00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5Y82_00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C5Y82_00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C5Y82_00455	COG0512	Glutamine amidotransferase of anthranilate synthase
C5Y82_00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5Y82_00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C5Y82_00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C5Y82_00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C5Y82_00480	COG1396	sequence-specific DNA binding
C5Y82_00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5Y82_00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C5Y82_00570	COG4463	regulation of RNA biosynthetic process
C5Y82_00575	COG3880	PFAM UvrB UvrC protein
C5Y82_00580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C5Y82_00585	COG0542	response to heat
C5Y82_00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C5Y82_00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C5Y82_00600	COG4956	integral membrane protein (PIN domain superfamily)
C5Y82_00605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C5Y82_00610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C5Y82_00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C5Y82_00620	COG1045	serine acetyltransferase
C5Y82_00625	COG0215	cysteine-tRNA ligase activity
C5Y82_00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C5Y82_00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5Y82_00640	COG3688	RNA-binding protein containing a PIN domain
C5Y82_00645	COG1595	DNA-templated transcription, initiation
C5Y82_00650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C5Y82_00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C5Y82_00660	COG0250	Participates in transcription elongation, termination and antitermination
C5Y82_00665	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C5Y82_00670	COG0081	regulation of translation
C5Y82_00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C5Y82_00680	COG0222	ribosome binding
C5Y82_00685	COG2813	Specifically methylates the guanine in position
C5Y82_00690	COG0085	RNA polymerase activity
C5Y82_00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C5Y82_00700	COG1358	cellular component organization or biogenesis
C5Y82_00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C5Y82_00710	COG0049	tRNA binding
C5Y82_00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C5Y82_00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C5Y82_00725	COG0596	Alpha beta hydrolase
C5Y82_00730	COG0051	transcription antitermination factor activity, RNA binding
C5Y82_00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C5Y82_00740	COG0088	Forms part of the polypeptide exit tunnel
C5Y82_00745	COG0089	rRNA binding
C5Y82_00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C5Y82_00755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C5Y82_00760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C5Y82_00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C5Y82_00770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C5Y82_00775	COG0255	Belongs to the universal ribosomal protein uL29 family
C5Y82_00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C5Y82_00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C5Y82_00790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C5Y82_00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C5Y82_00800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C5Y82_00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C5Y82_00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C5Y82_00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C5Y82_00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C5Y82_00825	COG1841	ribosomal large subunit assembly
C5Y82_00830	COG0200	Binds to the 23S rRNA
C5Y82_00835	COG0201	protein transport
C5Y82_00840	COG0563	adenylate kinase activity
C5Y82_00845	COG0024	Methionine aminopeptidase
C5Y82_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C5Y82_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C5Y82_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C5Y82_00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C5Y82_00875	COG0202	RNA polymerase activity
C5Y82_00880	COG0203	ribosomal protein L17
C5Y82_00885	COG1122	ATPase activity
C5Y82_00890	COG1122	ATPase activity
C5Y82_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C5Y82_00900	COG0101	tRNA pseudouridine synthase activity
C5Y82_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C5Y82_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C5Y82_00915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5Y82_00945	COG0860	N-Acetylmuramoyl-L-alanine amidase
C5Y82_00950	COG0489	protein tyrosine kinase activity
C5Y82_00960	COG2194	sulfuric ester hydrolase activity
C5Y82_00965	COG0726	polysaccharide deacetylase
C5Y82_00995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5Y82_01000	COG0659	secondary active sulfate transmembrane transporter activity
C5Y82_01005	COG0385	Bile acid
C5Y82_01010	COG3876	Protein conserved in bacteria
C5Y82_01015	COG1472	Belongs to the glycosyl hydrolase 3 family
C5Y82_01020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C5Y82_01025	COG1263	PTS System
C5Y82_01025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5Y82_01030	COG1737	Transcriptional regulator
C5Y82_01035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C5Y82_01070	COG1595	DNA-templated transcription, initiation
C5Y82_01075	COG5662	AntiSigma factor
C5Y82_01080	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C5Y82_01085	COG4856	YbbR-like protein
C5Y82_01090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C5Y82_01100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C5Y82_01115	COG1131	(ABC) transporter
C5Y82_01135	COG2311	Membrane
C5Y82_01140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5Y82_01155	COG1113	amino acid transport
C5Y82_01160	COG0584	glycerophosphoryl diester phosphodiesterase
C5Y82_01165	COG2271	Major facilitator Superfamily
C5Y82_01170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5Y82_01175	COG1331	Highly conserved protein containing a thioredoxin domain
C5Y82_01195	COG1937	Protein conserved in bacteria
C5Y82_01200	COG2210	Belongs to the sulfur carrier protein TusA family
C5Y82_01205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5Y82_01210	COG0425	Belongs to the sulfur carrier protein TusA family
C5Y82_01210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5Y82_01215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5Y82_01215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5Y82_01220	COG0425	Belongs to the sulfur carrier protein TusA family
C5Y82_01225	COG0730	response to heat
C5Y82_01230	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C5Y82_01235	COG2814	Major facilitator Superfamily
C5Y82_01245	COG1846	Transcriptional regulator
C5Y82_01255	COG1683	Conserved Protein
C5Y82_01265	COG0656	L-ascorbic acid biosynthetic process
C5Y82_01270	COG0371	Dehydrogenase
C5Y82_01280	COG0531	amino acid
C5Y82_01290	COG3711	transcriptional antiterminator
C5Y82_01295	COG1263	PTS System
C5Y82_01295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5Y82_01295	COG2190	(PTS) system
C5Y82_01300	COG2723	6-phospho-beta-galactosidase activity
C5Y82_01325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5Y82_01325	COG3711	transcriptional antiterminator
C5Y82_01330	COG1940	carbohydrate kinase activity
C5Y82_01335	COG0383	alpha-mannosidase activity
C5Y82_01340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5Y82_01345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5Y82_01350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5Y82_01350	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5Y82_01355	COG1404	Belongs to the peptidase S8 family
C5Y82_01370	COG0833	amino acid
C5Y82_01375	COG2040	homocysteine
C5Y82_01380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C5Y82_01385	COG1695	Transcriptional regulator
C5Y82_01395	COG2814	Major facilitator Superfamily
C5Y82_01415	COG1404	Belongs to the peptidase S8 family
C5Y82_01425	COG1309	transcriptional regulator
C5Y82_01430	COG1917	Cupin 2, conserved barrel domain protein
C5Y82_01435	COG1063	alcohol dehydrogenase
C5Y82_01440	COG1846	Transcriptional regulator
C5Y82_01445	COG0318	PFAM AMP-dependent synthetase and ligase
C5Y82_01450	COG0531	amino acid
C5Y82_01460	COG0596	Alpha beta hydrolase
C5Y82_01465	COG1115	amino acid carrier protein
C5Y82_01470	COG2066	Belongs to the glutaminase family
C5Y82_01475	COG4191	Histidine kinase
C5Y82_01480	COG0784	Response regulator, receiver
C5Y82_01485	COG1405	negative regulation of cell septum assembly
C5Y82_01485	COG3012	SEC-C Motif Domain Protein
C5Y82_01495	COG0667	Aldo Keto reductase
C5Y82_01500	COG3290	protein histidine kinase activity
C5Y82_01505	COG3279	Response regulator of the LytR AlgR family
C5Y82_01510	COG4555	ABC transporter
C5Y82_01515	COG1668	transmembrane transport
C5Y82_01530	COG3773	Cell wall hydrolase
C5Y82_01535	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_01545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5Y82_01550	COG2310	stress, protein
C5Y82_01555	COG2310	stress, protein
C5Y82_01560	COG2310	stress, protein
C5Y82_01565	COG0861	Integral membrane protein TerC family
C5Y82_01595	COG3853	Toxic anion resistance protein (TelA)
C5Y82_01600	COG0517	IMP dehydrogenase activity
C5Y82_01600	COG4175	Glycine betaine
C5Y82_01605	COG4176	ABC-type proline glycine betaine transport system permease component
C5Y82_01610	COG2113	Glycine betaine
C5Y82_01625	COG1473	amidohydrolase
C5Y82_01630	COG1288	antiporter activity
C5Y82_01635	COG0039	L-malate dehydrogenase activity
C5Y82_01640	COG1620	l-lactate permease
C5Y82_01645	COG1609	Transcriptional regulator
C5Y82_01650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5Y82_01655	COG0561	phosphatase activity
C5Y82_01660	COG0673	inositol 2-dehydrogenase activity
C5Y82_01665	COG0738	Major facilitator superfamily
C5Y82_01670	COG1280	lysine exporter protein (LysE YggA)
C5Y82_01680	COG3403	YqcI/YcgG family
C5Y82_01685	COG1113	amino acid transport
C5Y82_01690	COG3665	Urea carboxylase-associated protein
C5Y82_01695	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C5Y82_01700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C5Y82_01710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C5Y82_01715	COG1609	Transcriptional regulator
C5Y82_01720	COG0477	Major facilitator Superfamily
C5Y82_01725	COG2226	methyltransferase
C5Y82_01730	COG0583	DNA-binding transcription factor activity
C5Y82_01735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5Y82_01740	COG3458	cephalosporin-C deacetylase activity
C5Y82_01750	COG3541	Predicted nucleotidyltransferase
C5Y82_01755	COG0506	proline dehydrogenase activity
C5Y82_01760	COG1012	belongs to the aldehyde dehydrogenase family
C5Y82_01765	COG2508	Transcriptional regulator
C5Y82_01770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C5Y82_01775	COG0765	amino acid transport
C5Y82_01780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5Y82_01790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C5Y82_01795	COG1522	sequence-specific DNA binding
C5Y82_01800	COG2746	aminoglycoside 3-N-acetyltransferase activity
C5Y82_01810	COG3290	protein histidine kinase activity
C5Y82_01810	COG0840	transmembrane signaling receptor activity
C5Y82_01815	COG3209	COG3209 Rhs family protein
C5Y82_01840	COG3842	ATPase activity
C5Y82_01845	COG1176	ABC-type spermidine putrescine transport system, permease component I
C5Y82_01855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5Y82_01860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5Y82_01865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5Y82_01880	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C5Y82_01885	COG0697	spore germination
C5Y82_01890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5Y82_01905	COG2364	Membrane
C5Y82_01915	COG3764	Sortase (surface protein transpeptidase)
C5Y82_01920	COG2002	toxin-antitoxin pair type II binding
C5Y82_01925	COG1126	abc transporter atp-binding protein
C5Y82_01930	COG0765	amino acid transport
C5Y82_01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5Y82_01940	COG0412	Dienelactone hydrolase
C5Y82_01945	COG0833	amino acid
C5Y82_01950	COG3104	oligopeptide transport
C5Y82_01955	COG5434	Belongs to the glycosyl hydrolase 28 family
C5Y82_01970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5Y82_01975	COG0765	amino acid transport
C5Y82_01980	COG1126	abc transporter atp-binding protein
C5Y82_01990	COG2079	MmgE PrpD family protein
C5Y82_01995	COG0745	RESPONSE REGULATOR receiver
C5Y82_02000	COG3850	Histidine kinase
C5Y82_02000	COG5002	protein histidine kinase activity
C5Y82_02005	COG1366	Belongs to the anti-sigma-factor antagonist family
C5Y82_02010	COG0527	aspartate kinase activity
C5Y82_02015	COG2814	Major facilitator Superfamily
C5Y82_02020	COG1309	transcriptional regulator
C5Y82_02030	COG0640	Transcriptional regulator
C5Y82_02035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5Y82_02040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C5Y82_02045	COG0531	amino acid
C5Y82_02050	COG1012	belongs to the aldehyde dehydrogenase family
C5Y82_02055	COG2249	NAD(P)H dehydrogenase (quinone) activity
C5Y82_02060	COG4549	nuclear export factor GLE1
C5Y82_02065	COG2372	response to copper ion
C5Y82_02065	COG1276	copper resistance
C5Y82_02070	COG2213	PTS system mannitol-specific
C5Y82_02075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5Y82_02080	COG0246	Mannitol dehydrogenase
C5Y82_02085	COG0840	transmembrane signaling receptor activity
C5Y82_02105	COG0346	lactoylglutathione lyase activity
C5Y82_02115	COG0561	phosphatase activity
C5Y82_02120	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C5Y82_02125	COG1914	H( )-stimulated, divalent metal cation uptake system
C5Y82_02130	COG4336	lyase activity
C5Y82_02135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C5Y82_02140	COG1984	allophanate hydrolase subunit 2
C5Y82_02145	COG1414	Transcriptional regulator
C5Y82_02150	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C5Y82_02155	COG2755	lipolytic protein G-D-S-L family
C5Y82_02165	COG3711	transcriptional antiterminator
C5Y82_02170	COG2226	methyltransferase
C5Y82_02175	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_02180	COG3871	stress protein (general stress protein 26)
C5Y82_02205	COG2814	Major facilitator Superfamily
C5Y82_02210	COG1802	Transcriptional regulator
C5Y82_02215	COG0697	spore germination
C5Y82_02220	COG0473	3-isopropylmalate dehydrogenase activity
C5Y82_02225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C5Y82_02225	COG0551	DNA topoisomerase type I activity
C5Y82_02230	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C5Y82_02235	COG3706	GGDEF domain
C5Y82_02240	COG5298	Protein conserved in bacteria
C5Y82_02245	COG1215	transferase activity, transferring glycosyl groups
C5Y82_02255	COG0531	amino acid
C5Y82_02260	COG0028	Belongs to the TPP enzyme family
C5Y82_02265	COG5444	nuclease activity
C5Y82_02285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5Y82_02290	COG1914	H( )-stimulated, divalent metal cation uptake system
C5Y82_02295	COG2261	transglycosylase associated protein
C5Y82_02300	COG2217	Heavy metal translocating P-type atpase
C5Y82_02305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C5Y82_02310	COG3290	protein histidine kinase activity
C5Y82_02315	COG4565	transcriptional regulatory protein
C5Y82_02320	COG1301	dicarboxylic acid transport
C5Y82_02325	COG0628	permease
C5Y82_02330	COG1301	dicarboxylic acid transport
C5Y82_02335	COG1131	(ABC) transporter
C5Y82_02340	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C5Y82_02355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5Y82_02360	COG1181	Belongs to the D-alanine--D-alanine ligase family
C5Y82_02365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C5Y82_02380	COG0513	Belongs to the DEAD box helicase family
C5Y82_02385	COG3402	PFAM membrane-flanked domain
C5Y82_02390	COG3428	Bacterial PH domain
C5Y82_02395	COG0705	Rhomboid family
C5Y82_02400	COG0736	holo-[acyl-carrier-protein] synthase activity
C5Y82_02405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C5Y82_02410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5Y82_02415	COG0864	Transcriptional regulator
C5Y82_02420	COG2337	Toxic component of a toxin-antitoxin (TA) module
C5Y82_02425	COG1366	Belongs to the anti-sigma-factor antagonist family
C5Y82_02430	COG1366	Belongs to the anti-sigma-factor antagonist family
C5Y82_02435	COG2172	sigma factor antagonist activity
C5Y82_02440	COG2208	phosphoserine phosphatase activity
C5Y82_02445	COG1366	Belongs to the anti-sigma-factor antagonist family
C5Y82_02450	COG2172	sigma factor antagonist activity
C5Y82_02455	COG1191	sigma factor activity
C5Y82_02460	COG2208	phosphoserine phosphatase activity
C5Y82_02465	COG2183	response to ionizing radiation
C5Y82_02475	COG3091	SprT-like family
C5Y82_02480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C5Y82_02485	COG0022	dehydrogenase e1 component
C5Y82_02490	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5Y82_02495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5Y82_02500	COG3284	Transcriptional regulator
C5Y82_02560	COG1278	Cold shock
C5Y82_02565	COG1329	Transcriptional regulator
C5Y82_02570	COG1064	alcohol dehydrogenase
C5Y82_02575	COG0789	Transcriptional regulator
C5Y82_02590	COG0477	Major facilitator Superfamily
C5Y82_02610	COG0583	DNA-binding transcription factor activity
C5Y82_02645	COG0252	asparaginase activity
C5Y82_02665	COG2814	Major facilitator Superfamily
C5Y82_02670	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C5Y82_02675	COG2409	Drug exporters of the RND superfamily
C5Y82_02680	COG4585	Histidine kinase
C5Y82_02685	COG2197	response regulator
C5Y82_02720	COG1309	transcriptional regulator
C5Y82_02725	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C5Y82_02730	COG1846	Transcriptional regulator
C5Y82_02735	COG0778	Nitroreductase
C5Y82_02750	COG1396	sequence-specific DNA binding
C5Y82_02760	COG0456	acetyltransferase
C5Y82_02765	COG0583	DNA-binding transcription factor activity
C5Y82_02770	COG0667	Aldo Keto reductase
C5Y82_02790	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C5Y82_02795	COG0697	spore germination
C5Y82_02805	COG1301	dicarboxylic acid transport
C5Y82_02845	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C5Y82_02850	COG0802	atpase or kinase
C5Y82_02855	COG1214	PFAM Peptidase M22, glycoprotease
C5Y82_02860	COG0456	acetyltransferase
C5Y82_02865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C5Y82_02870	COG0488	(ABC) transporter
C5Y82_02875	COG0315	cyclic pyranopterin monophosphate synthase activity
C5Y82_02880	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C5Y82_02885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C5Y82_02890	COG0805	protein transport
C5Y82_02905	COG1266	CAAX protease self-immunity
C5Y82_02910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C5Y82_02915	COG0459	protein refolding
C5Y82_02935	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C5Y82_02940	COG0823	Involved in the tonB-independent uptake of proteins
C5Y82_02950	COG2132	Multicopper oxidase
C5Y82_02955	COG1113	amino acid transport
C5Y82_02960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C5Y82_02965	COG0714	Associated with various cellular activities
C5Y82_02970	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C5Y82_02975	COG1305	Transglutaminase-like
C5Y82_02980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C5Y82_02980	COG0519	Catalyzes the synthesis of GMP from XMP
C5Y82_02990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C5Y82_02995	COG2207	Transcriptional regulator
C5Y82_03005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5Y82_03020	COG1595	DNA-templated transcription, initiation
C5Y82_03030	COG2814	Major facilitator Superfamily
C5Y82_03035	COG0583	DNA-binding transcription factor activity
C5Y82_03040	COG2252	PERMEase
C5Y82_03045	COG3064	Membrane
C5Y82_03050	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C5Y82_03060	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C5Y82_03065	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C5Y82_03070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C5Y82_03075	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C5Y82_03080	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C5Y82_03085	COG0047	phosphoribosylformylglycinamidine synthase activity
C5Y82_03090	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C5Y82_03095	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C5Y82_03100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C5Y82_03105	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C5Y82_03110	COG0138	bifunctional purine biosynthesis protein purh
C5Y82_03115	COG0151	Belongs to the GarS family
C5Y82_03135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C5Y82_03140	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C5Y82_03145	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C5Y82_03150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5Y82_03165	COG4496	protein, YerC YecD
C5Y82_03170	COG0069	glutamate synthase activity
C5Y82_03185	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C5Y82_03190	COG0210	DNA helicase
C5Y82_03195	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C5Y82_03200	COG4851	CamS sex pheromone cAM373 precursor
C5Y82_03230	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5Y82_03245	COG1960	acyl-CoA dehydrogenase activity
C5Y82_03265	COG0300	oxidoreductase activity
C5Y82_03265	COG4221	oxidoreductase activity
C5Y82_03265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5Y82_03265	COG3321	synthase
C5Y82_03275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C5Y82_03280	COG1785	Belongs to the alkaline phosphatase family
C5Y82_03285	COG1285	pathogenesis
C5Y82_03290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5Y82_03295	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C5Y82_03300	COG0154	amidase activity
C5Y82_03305	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C5Y82_03315	COG1309	transcriptional regulator
C5Y82_03320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5Y82_03325	COG1957	nucleoside hydrolase
C5Y82_03330	COG1597	lipid kinase activity
C5Y82_03335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C5Y82_03340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C5Y82_03350	COG5293	efflux transmembrane transporter activity
C5Y82_03355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5Y82_03370	COG1959	2 iron, 2 sulfur cluster binding
C5Y82_03375	COG0492	ferredoxin-NADP+ reductase activity
C5Y82_03390	COG1486	melibiose metabolic process
C5Y82_03400	COG2211	Major facilitator Superfamily
C5Y82_03430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C5Y82_03435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5Y82_03440	COG1442	glycosyl transferase family 8
C5Y82_03445	COG1216	Glycosyl transferase, family 2
C5Y82_03450	COG1442	glycosyl transferase family 8
C5Y82_03455	COG2223	nitrite transmembrane transporter activity
C5Y82_03465	COG0471	metal ion transport
C5Y82_03480	COG0071	Belongs to the small heat shock protein (HSP20) family
C5Y82_03495	COG0531	amino acid
C5Y82_03500	COG0457	Tetratricopeptide repeat
C5Y82_03500	COG0463	Glycosyl transferase, family 2
C5Y82_03505	COG0488	(ABC) transporter
C5Y82_03515	COG0789	Transcriptional regulator
C5Y82_03520	COG2814	Major facilitator Superfamily
C5Y82_03525	COG0488	(ABC) transporter
C5Y82_03530	COG0513	Belongs to the DEAD box helicase family
C5Y82_03535	COG2130	NADP-dependent
C5Y82_03555	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C5Y82_03555	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C5Y82_03560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C5Y82_03570	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5Y82_03570	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5Y82_03580	COG3290	protein histidine kinase activity
C5Y82_03585	COG4565	transcriptional regulatory protein
C5Y82_03590	COG3181	Tripartite tricarboxylate transporter family receptor
C5Y82_03595	COG2851	Citrate transporter
C5Y82_03605	COG3479	Phenolic acid decarboxylase
C5Y82_03610	COG1695	Transcriptional regulator
C5Y82_03615	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C5Y82_03620	COG1254	Belongs to the acylphosphatase family
C5Y82_03625	COG2258	MOSC domain
C5Y82_03635	COG0024	Methionine aminopeptidase
C5Y82_03640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5Y82_03640	COG1263	PTS System
C5Y82_03645	COG3739	integral membrane protein
C5Y82_03660	COG1368	sulfuric ester hydrolase activity
C5Y82_03665	COG0076	glutamate decarboxylase activity
C5Y82_03680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5Y82_03680	COG1263	PTS System
C5Y82_03685	COG0366	Alpha amylase catalytic
C5Y82_03690	COG2188	Transcriptional regulator
C5Y82_03695	COG0693	protein deglycase activity
C5Y82_03705	COG0737	Belongs to the 5'-nucleotidase family
C5Y82_03710	COG0693	protein deglycase activity
C5Y82_03715	COG4840	Belongs to the UPF0435 family
C5Y82_03720	COG1115	amino acid carrier protein
C5Y82_03730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C5Y82_03735	COG4980	gas vesicle protein
C5Y82_03740	COG1295	ribonuclease BN
C5Y82_03745	COG0477	Major facilitator Superfamily
C5Y82_03755	COG0387	Pfam Sodium calcium exchanger
C5Y82_03765	COG0217	transcriptional regulatory protein
C5Y82_03775	COG0668	transmembrane transport
C5Y82_03780	COG0535	radical SAM domain protein
C5Y82_03790	COG0726	polysaccharide deacetylase
C5Y82_03800	COG0598	Magnesium transport protein CorA
C5Y82_03810	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C5Y82_03815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C5Y82_03840	COG0789	Transcriptional regulator
C5Y82_03860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C5Y82_03900	COG2076	Multidrug Resistance protein
C5Y82_03905	COG2076	Multidrug Resistance protein
C5Y82_03910	COG1309	transcriptional regulator
C5Y82_03920	COG4637	Psort location Cytoplasmic, score
C5Y82_03925	COG2755	lipolytic protein G-D-S-L family
C5Y82_03930	COG0492	ferredoxin-NADP+ reductase activity
C5Y82_03935	COG2169	Transcriptional regulator
C5Y82_03945	COG1132	(ABC) transporter
C5Y82_03950	COG1742	UPF0060 membrane protein
C5Y82_03955	COG1595	DNA-templated transcription, initiation
C5Y82_03975	COG2318	DinB family
C5Y82_03985	COG1846	Transcriptional regulator
C5Y82_03990	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C5Y82_03990	COG0392	lysyltransferase activity
C5Y82_04015	COG0778	Nitroreductase
C5Y82_04035	COG2137	regulation of response to DNA damage stimulus
C5Y82_04060	COG0463	Glycosyl transferase, family 2
C5Y82_04065	COG4485	Bacterial membrane protein, YfhO
C5Y82_04085	COG2140	Oxalate decarboxylase
C5Y82_04095	COG1191	sigma factor activity
C5Y82_04105	COG1988	membrane-bound metal-dependent
C5Y82_04110	COG1194	a g-specific adenine glycosylase
C5Y82_04120	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_04135	COG3557	Belongs to the UPF0374 family
C5Y82_04140	COG1132	(ABC) transporter
C5Y82_04145	COG0444	Belongs to the ABC transporter superfamily
C5Y82_04150	COG4608	Belongs to the ABC transporter superfamily
C5Y82_04155	COG0747	negative chemotaxis
C5Y82_04175	COG4129	membrane
C5Y82_04180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C5Y82_04185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C5Y82_04190	COG0735	belongs to the Fur family
C5Y82_04345	COG1368	sulfuric ester hydrolase activity
C5Y82_04350	COG0681	Belongs to the peptidase S26 family
C5Y82_04365	COG1131	(ABC) transporter
C5Y82_04395	COG3382	B3 4 domain protein
C5Y82_04400	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C5Y82_04410	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C5Y82_04420	COG2766	serine protein kinase
C5Y82_04425	COG2718	Belongs to the UPF0229 family
C5Y82_04430	COG1566	PFAM secretion protein HlyD family protein
C5Y82_04435	COG2814	Major facilitator Superfamily
C5Y82_04440	COG0655	NAD(P)H dehydrogenase (quinone) activity
C5Y82_04450	COG1278	Cold shock
C5Y82_04460	COG3706	GGDEF domain
C5Y82_04485	COG5577	PFAM Coat F domain
C5Y82_04490	COG5002	protein histidine kinase activity
C5Y82_04495	COG4085	toxin activity
C5Y82_04495	COG0737	Belongs to the 5'-nucleotidase family
C5Y82_04495	COG1525	nuclease
C5Y82_04500	COG3764	Sortase (surface protein transpeptidase)
C5Y82_04510	COG0564	pseudouridine synthase activity
C5Y82_04520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C5Y82_04525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5Y82_04525	COG3153	acetyltransferase
C5Y82_04540	COG3835	regulator
C5Y82_04545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C5Y82_04550	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C5Y82_04555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C5Y82_04560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C5Y82_04565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C5Y82_04575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C5Y82_04580	COG4585	Histidine kinase
C5Y82_04580	COG2203	Gaf domain
C5Y82_04585	COG2197	response regulator
C5Y82_04605	COG0753	catalase activity
C5Y82_04610	COG1959	2 iron, 2 sulfur cluster binding
C5Y82_04615	COG1017	nitric oxide dioxygenase activity
C5Y82_04615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5Y82_04620	COG2719	SpoVR family
C5Y82_04625	COG1785	Belongs to the alkaline phosphatase family
C5Y82_04630	COG0791	NLP P60 protein
C5Y82_04630	COG1388	LysM domain
C5Y82_04645	COG1595	DNA-templated transcription, initiation
C5Y82_04650	COG0204	Acyl-transferase
C5Y82_04655	COG1253	flavin adenine dinucleotide binding
C5Y82_04660	COG0789	Transcriptional regulator
C5Y82_04665	COG1253	flavin adenine dinucleotide binding
C5Y82_04680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C5Y82_04685	COG0584	glycerophosphoryl diester phosphodiesterase
C5Y82_04700	COG0668	transmembrane transport
C5Y82_04705	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C5Y82_04710	COG0726	polysaccharide deacetylase
C5Y82_04715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5Y82_04720	COG0589	response to stress
C5Y82_04730	COG1132	(ABC) transporter
C5Y82_04735	COG0702	epimerase
C5Y82_04745	COG3842	ATPase activity
C5Y82_04750	COG2508	Transcriptional regulator
C5Y82_04760	COG0189	ligase activity
C5Y82_04765	COG0189	ligase activity
C5Y82_04770	COG4399	Belongs to the UPF0754 family
C5Y82_04775	COG3679	Belongs to the UPF0342 family
C5Y82_04780	COG0561	phosphatase activity
C5Y82_04785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C5Y82_04795	COG1024	Enoyl-CoA hydratase
C5Y82_04805	COG0420	3'-5' exonuclease activity
C5Y82_04810	COG4717	serine-type aminopeptidase activity
C5Y82_04815	COG3481	metal-dependent phosphohydrolase, HD sub domain
C5Y82_04825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5Y82_04855	COG1846	Transcriptional regulator
C5Y82_04860	COG4980	gas vesicle protein
C5Y82_04875	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C5Y82_04880	COG0537	adenosine 5'-monophosphoramidase activity
C5Y82_04885	COG1131	(ABC) transporter
C5Y82_04890	COG4473	ABC transporter
C5Y82_04900	COG1473	amidohydrolase
C5Y82_04910	COG2329	Antibiotic biosynthesis monooxygenase
C5Y82_04915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5Y82_04920	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C5Y82_04935	COG1309	transcriptional regulator
C5Y82_04940	COG1511	domain protein
C5Y82_04945	COG1363	Peptidase, m42
C5Y82_04950	COG1301	dicarboxylic acid transport
C5Y82_04960	COG1234	tRNA 3'-trailer cleavage
C5Y82_04965	COG0095	Lipoate-protein ligase
C5Y82_04970	COG0318	PFAM AMP-dependent synthetase and ligase
C5Y82_04980	COG0501	Belongs to the peptidase M48B family
C5Y82_04985	COG1404	Belongs to the peptidase S8 family
C5Y82_04990	COG0406	alpha-ribazole phosphatase activity
C5Y82_04995	COG0840	transmembrane signaling receptor activity
C5Y82_05000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5Y82_05000	COG0723	plastoquinol--plastocyanin reductase activity
C5Y82_05005	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_05015	COG4903	ComK protein
C5Y82_05030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5Y82_05035	COG2814	Major facilitator Superfamily
C5Y82_05040	COG2732	(Barnase) inhibitor
C5Y82_05045	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5Y82_05050	COG4605	iron ion homeostasis
C5Y82_05055	COG4604	ABC transporter, ATP-binding protein
C5Y82_05060	COG4607	ABC-type enterochelin transport system periplasmic component
C5Y82_05065	COG1316	TRANSCRIPTIONal
C5Y82_05075	COG0398	Pfam SNARE associated Golgi protein
C5Y82_05080	COG0681	Belongs to the peptidase S26 family
C5Y82_05085	COG3180	Ammonia monooxygenase
C5Y82_05095	COG0501	Belongs to the peptidase M48B family
C5Y82_05100	COG2259	Doxx family
C5Y82_05105	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C5Y82_05110	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C5Y82_05115	COG1074	ATP-dependent DNA helicase activity
C5Y82_05120	COG0420	3'-5' exonuclease activity
C5Y82_05125	COG0419	ATPase involved in DNA repair
C5Y82_05130	COG1403	HNH endonuclease
C5Y82_05170	COG5337	Spore coat protein CotH
C5Y82_05180	COG0179	Fumarylacetoacetate (FAA) hydrolase
C5Y82_05195	COG0367	asparagine synthase
C5Y82_05210	COG1562	ergosterol biosynthetic process
C5Y82_05215	COG0534	Mate efflux family protein
C5Y82_05220	COG2207	Transcriptional regulator
C5Y82_05220	COG1917	Cupin 2, conserved barrel domain protein
C5Y82_05250	COG0076	glutamate decarboxylase activity
C5Y82_05280	COG0646	methionine synthase
C5Y82_05280	COG1410	methionine synthase
C5Y82_05285	COG0646	methionine synthase
C5Y82_05285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C5Y82_05290	COG1666	GTP binding
C5Y82_05295	COG2996	Protein conserved in bacteria
C5Y82_05305	COG0840	transmembrane signaling receptor activity
C5Y82_05310	COG1307	EDD domain protein, DegV family
C5Y82_05315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C5Y82_05335	COG0561	phosphatase activity
C5Y82_05340	COG1073	alpha beta
C5Y82_05345	COG2151	metal-sulfur cluster biosynthetic enzyme
C5Y82_05350	COG0277	FAD linked oxidase domain protein
C5Y82_05355	COG2271	Major facilitator Superfamily
C5Y82_05360	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C5Y82_05370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C5Y82_05375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C5Y82_05380	COG0505	Belongs to the CarA family
C5Y82_05385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C5Y82_05390	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C5Y82_05400	COG2814	Major facilitator Superfamily
C5Y82_05410	COG2267	carboxylic ester hydrolase activity
C5Y82_05420	COG1744	ABC transporter substrate-binding protein PnrA-like
C5Y82_05435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C5Y82_05440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5Y82_05445	COG5504	Zn-dependent protease
C5Y82_05450	COG0444	Belongs to the ABC transporter superfamily
C5Y82_05455	COG4608	Belongs to the ABC transporter superfamily
C5Y82_05465	COG0601	transmembrane transport
C5Y82_05470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5Y82_05490	COG0180	Tryptophanyl-tRNA synthetase
C5Y82_05500	COG4166	transmembrane transport
C5Y82_05505	COG0601	transmembrane transport
C5Y82_05510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5Y82_05515	COG0444	Belongs to the ABC transporter superfamily
C5Y82_05520	COG4608	Belongs to the ABC transporter superfamily
C5Y82_05530	COG0456	acetyltransferase
C5Y82_05535	COG1393	Belongs to the ArsC family
C5Y82_05540	COG0861	Integral membrane protein TerC family
C5Y82_05545	COG4862	establishment of competence for transformation
C5Y82_05550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5Y82_05560	COG1164	Oligoendopeptidase f
C5Y82_05570	COG2346	COG2346, Truncated hemoglobins
C5Y82_05575	COG0741	lytic transglycosylase activity
C5Y82_05580	COG4116	CYTH
C5Y82_05590	COG2357	RelA SpoT domain protein
C5Y82_05595	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C5Y82_05600	COG0564	pseudouridine synthase activity
C5Y82_05605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C5Y82_05610	COG0569	domain protein
C5Y82_05610	COG0475	glutathione-regulated potassium exporter activity
C5Y82_05615	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C5Y82_05620	COG0352	thiamine-phosphate diphosphorylase activity
C5Y82_05630	COG2104	thiamine diphosphate biosynthetic process
C5Y82_05635	COG2022	thiamine diphosphate biosynthetic process
C5Y82_05640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C5Y82_05645	COG0351	phosphomethylpyrimidine kinase
C5Y82_05650	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C5Y82_05705	COG0210	DNA helicase
C5Y82_05715	COG2153	protein acetylation
C5Y82_05720	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C5Y82_05725	COG2382	esterase
C5Y82_05730	COG0626	cystathionine gamma-synthase activity
C5Y82_05735	COG0626	cystathionine gamma-synthase activity
C5Y82_05765	COG0825	malonyl-CoA metabolic process
C5Y82_05800	COG0457	Tetratricopeptide repeat
C5Y82_05810	COG5444	nuclease activity
C5Y82_05835	COG0583	DNA-binding transcription factor activity
C5Y82_05850	COG0583	DNA-binding transcription factor activity
C5Y82_05855	COG2807	transmembrane transport
C5Y82_05865	COG0457	Tetratricopeptide repeat
C5Y82_05890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5Y82_05905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5Y82_05910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5Y82_05915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5Y82_05920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5Y82_05945	COG2856	Zn peptidase
C5Y82_05950	COG5632	N-Acetylmuramoyl-L-alanine amidase
C5Y82_05950	COG3409	Peptidoglycan-binding domain 1 protein
C5Y82_05965	COG0306	phosphate transporter
C5Y82_05970	COG1392	Phosphate transport regulator
C5Y82_05980	COG0405	Gamma-glutamyltransferase
C5Y82_05995	COG3775	system Galactitol-specific IIC component
C5Y82_06010	COG1063	alcohol dehydrogenase
C5Y82_06015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C5Y82_06020	COG0022	dehydrogenase e1 component
C5Y82_06020	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5Y82_06025	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5Y82_06030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5Y82_06035	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_06040	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_06045	COG2390	Transcriptional regulator
C5Y82_06055	COG0531	amino acid
C5Y82_06060	COG0346	lactoylglutathione lyase activity
C5Y82_06065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5Y82_06070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C5Y82_06075	COG2362	D-Aminopeptidase
C5Y82_06080	COG0601	transmembrane transport
C5Y82_06085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5Y82_06090	COG0444	Belongs to the ABC transporter superfamily
C5Y82_06095	COG4166	transmembrane transport
C5Y82_06100	COG1619	proteins homologs of microcin C7 resistance protein MccF
C5Y82_06105	COG4948	Mandelate Racemase Muconate Lactonizing
C5Y82_06110	COG0791	NLP P60 protein
C5Y82_06115	COG4608	Belongs to the ABC transporter superfamily
C5Y82_06120	COG1834	amidinotransferase
C5Y82_06125	COG1607	acyl-coa hydrolase
C5Y82_06130	COG1695	Transcriptional regulator
C5Y82_06145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5Y82_06160	COG2076	Multidrug Resistance protein
C5Y82_06165	COG2076	Multidrug Resistance protein
C5Y82_06175	COG0788	formyltetrahydrofolate deformylase activity
C5Y82_06185	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C5Y82_06190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C5Y82_06195	COG0457	Tetratricopeptide repeat
C5Y82_06205	COG1764	response to oxidative stress
C5Y82_06210	COG1846	Transcriptional regulator
C5Y82_06215	COG1764	response to oxidative stress
C5Y82_06220	COG0590	tRNA wobble adenosine to inosine editing
C5Y82_06225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C5Y82_06230	COG1404	Belongs to the peptidase S8 family
C5Y82_06235	COG0745	RESPONSE REGULATOR receiver
C5Y82_06240	COG5002	protein histidine kinase activity
C5Y82_06240	COG3850	Histidine kinase
C5Y82_06245	COG3212	peptidase
C5Y82_06250	COG3212	peptidase
C5Y82_06260	COG2239	Acts as a magnesium transporter
C5Y82_06270	COG0583	DNA-binding transcription factor activity
C5Y82_06285	COG0789	Transcriptional regulator
C5Y82_06295	COG1846	Transcriptional regulator
C5Y82_06300	COG3300	MHYT domain
C5Y82_06300	COG5001	Diguanylate cyclase
C5Y82_06305	COG0586	Pfam SNARE associated Golgi protein
C5Y82_06310	COG0861	Integral membrane protein TerC family
C5Y82_06315	COG1191	sigma factor activity
C5Y82_06335	COG0501	Belongs to the peptidase M48B family
C5Y82_06340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C5Y82_06345	COG2323	membrane
C5Y82_06350	COG3594	Acyltransferase
C5Y82_06355	COG5002	protein histidine kinase activity
C5Y82_06360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C5Y82_06365	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C5Y82_06370	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
C5Y82_06375	COG0436	Aminotransferase
C5Y82_06380	COG1850	ribulose-bisphosphate carboxylase activity
C5Y82_06385	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
C5Y82_06390	COG0235	Class ii aldolase
C5Y82_06395	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C5Y82_06405	COG3852	Histidine kinase
C5Y82_06410	COG1846	Transcriptional regulator
C5Y82_06415	COG1360	Flagellar Motor Protein
C5Y82_06420	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C5Y82_06425	COG0542	response to heat
C5Y82_06430	COG3949	Membrane
C5Y82_06435	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C5Y82_06440	COG0720	synthase
C5Y82_06445	COG0602	queuosine metabolic process
C5Y82_06450	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C5Y82_06470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5Y82_06475	COG4873	Protein conserved in bacteria
C5Y82_06485	COG3773	Cell wall hydrolase
C5Y82_06495	COG2244	polysaccharide biosynthetic process
C5Y82_06500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5Y82_06505	COG2217	Heavy metal translocating P-type atpase
C5Y82_06510	COG0006	proline dipeptidase activity
C5Y82_06515	COG1609	Transcriptional regulator
C5Y82_06520	COG3711	transcriptional antiterminator
C5Y82_06525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5Y82_06525	COG1263	PTS System
C5Y82_06525	COG2190	(PTS) system
C5Y82_06530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5Y82_06535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C5Y82_06545	COG1533	DNA photolyase activity
C5Y82_06550	COG0840	transmembrane signaling receptor activity
C5Y82_06560	COG2084	Dehydrogenase
C5Y82_06570	COG2340	Cysteine-rich secretory protein family
C5Y82_06575	COG0768	penicillin binding
C5Y82_06580	COG4191	Histidine kinase
C5Y82_06585	COG0436	Aminotransferase
C5Y82_06590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C5Y82_06595	COG1714	RDD family
C5Y82_06605	COG0835	chemotaxis
C5Y82_06605	COG0784	Response regulator, receiver
C5Y82_06620	COG2814	Major facilitator Superfamily
C5Y82_06625	COG1376	ErfK ybiS ycfS ynhG family protein
C5Y82_06630	COG1408	metallophosphoesterase
C5Y82_06635	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_06640	COG2200	EAL domain
C5Y82_06645	COG3546	catalase activity
C5Y82_06650	COG4703	Protein of unknown function (DUF1797)
C5Y82_06655	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C5Y82_06665	COG0517	IMP dehydrogenase activity
C5Y82_06670	COG0583	DNA-binding transcription factor activity
C5Y82_06680	COG0716	FMN binding
C5Y82_06690	COG0716	FMN binding
C5Y82_06695	COG2171	N-acyltransferase activity
C5Y82_06700	COG1473	amidohydrolase
C5Y82_06710	COG0668	transmembrane transport
C5Y82_06715	COG0450	alkyl hydroperoxide reductase
C5Y82_06720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5Y82_06735	COG0746	molybdenum cofactor guanylyltransferase activity
C5Y82_06740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C5Y82_06750	COG1763	Mo-molybdopterin cofactor biosynthetic process
C5Y82_06755	COG0314	molybdopterin synthase activity
C5Y82_06760	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C5Y82_06775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5Y82_06780	COG1136	(ABC) transporter
C5Y82_06785	COG0577	efflux transmembrane transporter activity
C5Y82_06790	COG1349	DNA-binding transcription factor activity
C5Y82_06795	COG1105	Belongs to the carbohydrate kinase PfkB family
C5Y82_06800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5Y82_06800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5Y82_06800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5Y82_06815	COG0488	(ABC) transporter
C5Y82_06825	COG2309	aminopeptidase activity
C5Y82_06830	COG1077	Cell shape determining protein MreB Mrl
C5Y82_06835	COG2002	toxin-antitoxin pair type II binding
C5Y82_06840	COG3852	Histidine kinase
C5Y82_06845	COG2105	PFAM AIG2 family protein
C5Y82_06845	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C5Y82_06850	COG0569	domain protein
C5Y82_06855	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C5Y82_06860	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C5Y82_06870	COG0561	phosphatase activity
C5Y82_06890	COG0242	peptide deformylase activity
C5Y82_06905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C5Y82_06910	COG0022	dehydrogenase e1 component
C5Y82_06915	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5Y82_06920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5Y82_06925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5Y82_06940	COG1982	Orn Lys Arg decarboxylase major
C5Y82_06945	COG4476	Belongs to the UPF0223 family
C5Y82_06950	COG4493	Belongs to the UPF0637 family
C5Y82_06960	COG0483	inositol monophosphate 1-phosphatase activity
C5Y82_06985	COG4896	Protein conserved in bacteria
C5Y82_06995	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C5Y82_07000	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C5Y82_07005	COG2066	Belongs to the glutaminase family
C5Y82_07010	COG4838	Belongs to the UPF0358 family
C5Y82_07015	COG0772	Belongs to the SEDS family
C5Y82_07020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C5Y82_07030	COG1612	heme a metabolic process
C5Y82_07035	COG0109	protoheme IX farnesyltransferase activity
C5Y82_07040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C5Y82_07040	COG2010	Cytochrome c
C5Y82_07045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C5Y82_07050	COG1845	cytochrome c oxidase, subunit III
C5Y82_07055	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C5Y82_07060	COG3336	cytochrome c oxidase
C5Y82_07070	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C5Y82_07075	COG2340	Cysteine-rich secretory protein family
C5Y82_07095	COG3679	Belongs to the UPF0342 family
C5Y82_07100	COG4471	UPF0298 protein
C5Y82_07105	COG0742	ribosomal rna small subunit methyltransferase
C5Y82_07110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C5Y82_07115	COG3314	Sporulation integral membrane protein YlbJ
C5Y82_07120	COG1752	Esterase of the alpha-beta hydrolase superfamily
C5Y82_07125	COG3480	Lon protease (S16) C-terminal proteolytic domain
C5Y82_07135	COG1399	metal-binding, possibly nucleic acid-binding protein
C5Y82_07140	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C5Y82_07150	COG0454	-acetyltransferase
C5Y82_07155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C5Y82_07160	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C5Y82_07165	COG2001	Belongs to the MraZ family
C5Y82_07170	COG0275	rRNA processing
C5Y82_07175	COG4839	cell division protein FtsL
C5Y82_07190	COG0768	penicillin binding
C5Y82_07195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C5Y82_07200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C5Y82_07205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C5Y82_07210	COG0772	Belongs to the SEDS family
C5Y82_07215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C5Y82_07220	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C5Y82_07225	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C5Y82_07230	COG3879	Bacterial protein of unknown function (DUF881)
C5Y82_07235	COG3879	Bacterial protein of unknown function (DUF881)
C5Y82_07240	COG3856	small basic protein
C5Y82_07245	COG0849	cell division
C5Y82_07250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C5Y82_07255	COG1404	Belongs to the peptidase S8 family
C5Y82_07255	COG4412	M6 family metalloprotease domain protein
C5Y82_07265	COG1191	sigma factor activity
C5Y82_07270	COG1191	sigma factor activity
C5Y82_07275	COG2390	Transcriptional regulator
C5Y82_07290	COG3730	PTS system glucitol sorbitol-specific
C5Y82_07295	COG3732	PTS system glucitol sorbitol-specific
C5Y82_07305	COG1119	ATPase activity
C5Y82_07310	COG1873	PFAM PRC-barrel domain
C5Y82_07320	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C5Y82_07325	COG1799	cell septum assembly
C5Y82_07330	COG0762	integral membrane protein
C5Y82_07335	COG2302	S4 RNA-binding domain
C5Y82_07340	COG3599	regulation of cell shape
C5Y82_07345	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C5Y82_07350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C5Y82_07355	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C5Y82_07360	COG0564	pseudouridine synthase activity
C5Y82_07365	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C5Y82_07370	COG2233	PERMEase
C5Y82_07375	COG0540	Belongs to the ATCase OTCase family
C5Y82_07380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C5Y82_07385	COG0505	Belongs to the CarA family
C5Y82_07390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C5Y82_07395	COG0543	2 iron, 2 sulfur cluster binding
C5Y82_07400	COG0167	dihydroorotate dehydrogenase activity
C5Y82_07405	COG0284	orotidine-5'-phosphate decarboxylase activity
C5Y82_07410	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C5Y82_07420	COG0175	sulfate reduction
C5Y82_07425	COG0306	phosphate transporter
C5Y82_07430	COG2046	Belongs to the sulfate adenylyltransferase family
C5Y82_07435	COG0529	Catalyzes the synthesis of activated sulfate
C5Y82_07440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C5Y82_07445	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C5Y82_07450	COG1648	precorrin-2 dehydrogenase activity
C5Y82_07460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C5Y82_07465	COG1561	YicC-like family, N-terminal region
C5Y82_07470	COG2052	Domain of unknown function (DUF370)
C5Y82_07475	COG0194	GDP metabolic process
C5Y82_07480	COG1758	RNA polymerase activity
C5Y82_07485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C5Y82_07490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C5Y82_07495	COG0242	peptide deformylase activity
C5Y82_07500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C5Y82_07505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C5Y82_07505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C5Y82_07510	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C5Y82_07515	COG0631	protein serine/threonine phosphatase activity
C5Y82_07520	COG0515	serine threonine protein kinase
C5Y82_07520	COG2815	serine threonine protein kinase
C5Y82_07525	COG1162	GTPase activity
C5Y82_07530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C5Y82_07535	COG1564	THIamine pyrophosphokinase
C5Y82_07545	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C5Y82_07550	COG1302	Protein conserved in bacteria
C5Y82_07555	COG1461	Dihydroxyacetone kinase
C5Y82_07560	COG1760	l-serine dehydratase
C5Y82_07565	COG1760	l-serine dehydratase
C5Y82_07570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C5Y82_07575	COG1349	DNA-binding transcription factor activity
C5Y82_07580	COG0416	fatty acid biosynthetic process
C5Y82_07585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C5Y82_07590	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_07595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5Y82_07605	COG1196	nuclear chromosome segregation
C5Y82_07610	COG0552	protein localization to endoplasmic reticulum
C5Y82_07615	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C5Y82_07620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C5Y82_07625	COG0228	four-way junction DNA binding
C5Y82_07630	COG1837	Belongs to the UPF0109 family
C5Y82_07640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C5Y82_07645	COG0336	Belongs to the RNA methyltransferase TrmD family
C5Y82_07650	COG0335	large ribosomal subunit rRNA binding
C5Y82_07655	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C5Y82_07660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C5Y82_07670	COG2257	FlhB HrpN YscU SpaS Family
C5Y82_07675	COG0045	succinate-CoA ligase (ADP-forming) activity
C5Y82_07680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C5Y82_07685	COG0758	DNA mediated transformation
C5Y82_07690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C5Y82_07695	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C5Y82_07700	COG4974	Belongs to the 'phage' integrase family
C5Y82_07705	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C5Y82_07710	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C5Y82_07715	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C5Y82_07720	COG1815	bacterial-type flagellum-dependent cell motility
C5Y82_07725	COG1558	bacterial-type flagellum-dependent cell motility
C5Y82_07730	COG1677	Flagellar hook-basal body complex protein FliE
C5Y82_07735	COG1766	The M ring may be actively involved in energy transduction
C5Y82_07740	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5Y82_07745	COG1317	bacterial-type flagellum organization
C5Y82_07750	COG1157	protein secretion by the type III secretion system
C5Y82_07755	COG2882	bacterial-type flagellum organization
C5Y82_07760	COG3334	PFAM MgtE intracellular
C5Y82_07765	COG3144	bacterial-type flagellum assembly
C5Y82_07770	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C5Y82_07775	COG4786	Flagellar basal body rod
C5Y82_07780	COG1582	Flagellar protein (FlbD)
C5Y82_07785	COG1580	Controls the rotational direction of flagella during chemotaxis
C5Y82_07790	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5Y82_07795	COG1776	CheC inhibitor of MCP methylation
C5Y82_07795	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5Y82_07800	COG2201	protein-glutamate methylesterase activity
C5Y82_07805	COG3190	flagellar
C5Y82_07810	COG1338	Plays a role in the flagellum-specific transport system
C5Y82_07815	COG1987	bacterial-type flagellum assembly
C5Y82_07820	COG1684	flagellar biosynthetic protein fliR
C5Y82_07825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C5Y82_07830	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C5Y82_07835	COG1419	protein localization to endoplasmic reticulum
C5Y82_07840	COG0455	bacterial-type flagellum organization
C5Y82_07845	COG2201	protein-glutamate methylesterase activity
C5Y82_07850	COG0643	Histidine kinase
C5Y82_07850	COG2198	Histidine kinase
C5Y82_07855	COG0835	chemotaxis
C5Y82_07860	COG1776	CheC inhibitor of MCP methylation
C5Y82_07870	COG1191	sigma factor activity
C5Y82_07880	COG0052	Belongs to the universal ribosomal protein uS2 family
C5Y82_07885	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C5Y82_07890	COG0528	UMP kinase activity
C5Y82_07895	COG0233	cytoplasmic translational termination
C5Y82_07900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C5Y82_07905	COG4589	Belongs to the CDS family
C5Y82_07910	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C5Y82_07915	COG0750	zinc metalloprotease
C5Y82_07920	COG0442	prolyl-tRNA aminoacylation
C5Y82_07925	COG2176	DNA-directed DNA polymerase activity
C5Y82_07950	COG0779	Required for maturation of 30S ribosomal subunits
C5Y82_07955	COG0195	Participates in both transcription termination and antitermination
C5Y82_07960	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C5Y82_07965	COG1358	cellular component organization or biogenesis
C5Y82_07970	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C5Y82_07975	COG1550	Protein conserved in bacteria
C5Y82_07980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C5Y82_07985	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C5Y82_07990	COG0196	riboflavin kinase activity
C5Y82_07995	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C5Y82_08000	COG1185	polyribonucleotide nucleotidyltransferase activity
C5Y82_08005	COG0726	polysaccharide deacetylase
C5Y82_08010	COG0612	Peptidase, M16
C5Y82_08020	COG1873	PFAM PRC-barrel domain
C5Y82_08025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5Y82_08030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C5Y82_08035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C5Y82_08040	COG0527	aspartate kinase activity
C5Y82_08050	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C5Y82_08055	COG0740	serine-type endopeptidase activity
C5Y82_08065	COG4980	gas vesicle protein
C5Y82_08065	COG1674	ftsk spoiiie
C5Y82_08070	COG2188	Transcriptional regulator
C5Y82_08075	COG2814	Major facilitator Superfamily
C5Y82_08080	COG1033	growth of symbiont in host cell
C5Y82_08080	COG2409	Drug exporters of the RND superfamily
C5Y82_08085	COG0612	Peptidase, M16
C5Y82_08090	COG0612	Peptidase, M16
C5Y82_08100	COG2409	Drug exporters of the RND superfamily
C5Y82_08100	COG1033	growth of symbiont in host cell
C5Y82_08105	COG0300	oxidoreductase activity
C5Y82_08120	COG1426	Protein conserved in bacteria
C5Y82_08125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C5Y82_08130	COG1546	Belongs to the CinA family
C5Y82_08130	COG1058	Belongs to the CinA family
C5Y82_08135	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C5Y82_08140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C5Y82_08145	COG1418	mRNA catabolic process
C5Y82_08150	COG1692	metallophosphoesterase
C5Y82_08155	COG2359	stage V sporulation protein S
C5Y82_08160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5Y82_08165	COG1063	alcohol dehydrogenase
C5Y82_08170	COG0156	8-amino-7-oxononanoate synthase activity
C5Y82_08175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C5Y82_08180	COG4550	Control of competence regulator ComK, YlbF/YmcA
C5Y82_08190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C5Y82_08195	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C5Y82_08215	COG1329	Transcriptional regulator
C5Y82_08220	COG4195	phage-related replication protein
C5Y82_08225	COG0457	Tetratricopeptide repeat
C5Y82_08230	COG1404	Belongs to the peptidase S8 family
C5Y82_08235	COG4195	phage-related replication protein
C5Y82_08240	COG1764	response to oxidative stress
C5Y82_08245	COG2076	Multidrug Resistance protein
C5Y82_08270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C5Y82_08275	COG1923	regulation of RNA biosynthetic process
C5Y82_08290	COG1780	Probably involved in ribonucleotide reductase function
C5Y82_08295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5Y82_08300	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5Y82_08305	COG4112	unkown
C5Y82_08315	COG0464	growth
C5Y82_08320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C5Y82_08325	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C5Y82_08330	COG0789	Transcriptional regulator
C5Y82_08335	COG0174	glutamine synthetase
C5Y82_08405	COG0305	Participates in initiation and elongation during chromosome replication
C5Y82_08415	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C5Y82_08440	COG4282	regulation of fungal-type cell wall biogenesis
C5Y82_08485	COG5484	DNA packaging
C5Y82_08490	COG1783	phage Terminase large subunit
C5Y82_08495	COG5518	Phage portal protein
C5Y82_08500	COG2369	cell adhesion
C5Y82_08510	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C5Y82_08515	COG4653	Phage capsid family
C5Y82_08565	COG3953	SLT domain
C5Y82_08565	COG5280	Phage tail tape measure protein TP901
C5Y82_08565	COG5280	Phage tail tape measure protein TP901
C5Y82_08565	COG3953	SLT domain
C5Y82_08570	COG1652	LysM domain
C5Y82_08575	COG4193	domain, Protein
C5Y82_08585	COG3628	GPW Gp25 family protein
C5Y82_08590	COG3299	homolog of phage Mu protein gp47
C5Y82_08595	COG3778	Protein conserved in bacteria
C5Y82_08630	COG3409	Peptidoglycan-binding domain 1 protein
C5Y82_08630	COG5632	N-Acetylmuramoyl-L-alanine amidase
C5Y82_08715	COG0457	Tetratricopeptide repeat
C5Y82_08765	COG5646	InterPro IPR014922
C5Y82_08785	COG0457	Tetratricopeptide repeat
C5Y82_08795	COG3619	membrane
C5Y82_08800	COG3285	dna ligase
C5Y82_08800	COG1793	dna ligase
C5Y82_08805	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C5Y82_08810	COG4876	unkown
C5Y82_08820	COG1959	2 iron, 2 sulfur cluster binding
C5Y82_08825	COG0702	epimerase
C5Y82_08830	COG0247	lactate metabolic process
C5Y82_08835	COG1139	Iron-sulfur cluster binding protein
C5Y82_08840	COG1556	Lactate utilization protein
C5Y82_08865	COG1309	transcriptional regulator
C5Y82_08870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C5Y82_08870	COG2124	cytochrome p450
C5Y82_08875	COG3591	Belongs to the peptidase S1B family
C5Y82_08880	COG3209	COG3209 Rhs family protein
C5Y82_08885	COG1366	Belongs to the anti-sigma-factor antagonist family
C5Y82_08900	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C5Y82_08905	COG1388	LysM domain
C5Y82_08910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C5Y82_08915	COG4224	UPF0291 protein
C5Y82_08920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C5Y82_08930	COG3763	UPF0154 protein
C5Y82_08940	COG0785	Cytochrome C biogenesis protein
C5Y82_08945	COG4846	Membrane protein involved in cytochrome C biogenesis
C5Y82_08955	COG0071	Belongs to the small heat shock protein (HSP20) family
C5Y82_08970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C5Y82_08975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5Y82_08995	COG0824	Thioesterase
C5Y82_09005	COG4841	protein insertion into membrane
C5Y82_09010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C5Y82_09015	COG1832	CoA-binding protein
C5Y82_09025	COG0187	DNA topoisomerase II activity
C5Y82_09030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C5Y82_09040	COG0738	Major facilitator superfamily
C5Y82_09060	COG0604	alcohol dehydrogenase
C5Y82_09075	COG2249	NAD(P)H dehydrogenase (quinone) activity
C5Y82_09080	COG1733	regulation of RNA biosynthetic process
C5Y82_09085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C5Y82_09090	COG0251	oxidation-reduction process
C5Y82_09160	COG0657	acetylesterase activity
C5Y82_09170	COG2723	6-phospho-beta-galactosidase activity
C5Y82_09175	COG2190	(PTS) system
C5Y82_09175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5Y82_09175	COG1263	PTS System
C5Y82_09190	COG2205	protein histidine kinase activity
C5Y82_09195	COG0745	RESPONSE REGULATOR receiver
C5Y82_09205	COG3507	Belongs to the glycosyl hydrolase 43 family
C5Y82_09210	COG1012	belongs to the aldehyde dehydrogenase family
C5Y82_09215	COG1486	melibiose metabolic process
C5Y82_09240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C5Y82_09255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5Y82_09285	COG5444	nuclease activity
C5Y82_09290	COG1846	Transcriptional regulator
C5Y82_09295	COG2814	Major facilitator Superfamily
C5Y82_09305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5Y82_09305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5Y82_09305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5Y82_09310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5Y82_09310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5Y82_09310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5Y82_09325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5Y82_09345	COG1012	belongs to the aldehyde dehydrogenase family
C5Y82_09355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C5Y82_09360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C5Y82_09365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5Y82_09370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C5Y82_09375	COG1024	Enoyl-CoA hydratase
C5Y82_09380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C5Y82_09385	COG0511	ligase activity, forming carbon-carbon bonds
C5Y82_09390	COG0439	Biotin carboxylase
C5Y82_09395	COG0318	PFAM AMP-dependent synthetase and ligase
C5Y82_09400	COG1960	acyl-CoA dehydrogenase activity
C5Y82_09405	COG1649	PFAM Uncharacterised BCR, COG1649
C5Y82_09415	COG1349	DNA-binding transcription factor activity
C5Y82_09425	COG3835	regulator
C5Y82_09430	COG0277	FAD linked oxidase domain protein
C5Y82_09435	COG0247	lactate metabolic process
C5Y82_09460	COG0166	Belongs to the GPI family
C5Y82_09465	COG0586	Pfam SNARE associated Golgi protein
C5Y82_09470	COG1587	Uroporphyrinogen-III synthase
C5Y82_09480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5Y82_09495	COG0534	Mate efflux family protein
C5Y82_09500	COG2027	D-alanyl-D-alanine carboxypeptidase
C5Y82_09505	COG4677	pectinesterase activity
C5Y82_09510	COG2323	membrane
C5Y82_09515	COG2146	nitrite reductase [NAD(P)H] activity
C5Y82_09520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C5Y82_09525	COG0493	'glutamate synthase
C5Y82_09530	COG0069	glutamate synthase activity
C5Y82_09530	COG0067	glutamate synthase
C5Y82_09530	COG0070	glutamate synthase
C5Y82_09535	COG0583	DNA-binding transcription factor activity
C5Y82_09545	COG1132	(ABC) transporter
C5Y82_09555	COG0454	-acetyltransferase
C5Y82_09565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5Y82_09570	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C5Y82_09575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C5Y82_09590	COG0243	molybdopterin cofactor binding
C5Y82_09605	COG1070	Carbohydrate kinase
C5Y82_09610	COG2115	Belongs to the xylose isomerase family
C5Y82_09615	COG1940	carbohydrate kinase activity
C5Y82_09625	COG2211	Major facilitator Superfamily
C5Y82_09635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5Y82_09640	COG1994	Peptidase M50
C5Y82_09660	COG1309	transcriptional regulator
C5Y82_09665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5Y82_09670	COG3708	Transcriptional regulator
C5Y82_09675	COG2378	regulation of single-species biofilm formation
C5Y82_09685	COG0640	Transcriptional regulator
C5Y82_09690	COG0531	amino acid
C5Y82_09695	COG0741	lytic transglycosylase activity
C5Y82_09705	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C5Y82_09710	COG2079	MmgE PrpD family protein
C5Y82_09715	COG0372	Belongs to the citrate synthase family
C5Y82_09720	COG2322	membrane
C5Y82_09730	COG3584	3D domain protein
C5Y82_09730	COG1388	LysM domain
C5Y82_09735	COG0514	ATP-dependent DNA helicase (RecQ)
C5Y82_09745	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C5Y82_09770	COG1012	belongs to the aldehyde dehydrogenase family
C5Y82_09775	COG1657	PFAM Prenyltransferase squalene oxidase
C5Y82_09780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C5Y82_09785	COG0385	Bile acid
C5Y82_09790	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5Y82_09795	COG0567	Dehydrogenase, E1 component
C5Y82_09800	COG4548	von Willebrand factor, type A
C5Y82_09805	COG0714	Associated with various cellular activities
C5Y82_09810	COG2032	superoxide dismutase activity
C5Y82_09815	COG0791	NLP P60 protein
C5Y82_09815	COG1388	LysM domain
C5Y82_09820	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C5Y82_09825	COG0534	Mate efflux family protein
C5Y82_09830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C5Y82_09835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C5Y82_09845	COG2962	Rard protein
C5Y82_09860	COG1733	regulation of RNA biosynthetic process
C5Y82_09865	COG0778	Nitroreductase
C5Y82_09875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5Y82_09880	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C5Y82_09885	COG3409	Peptidoglycan-binding domain 1 protein
C5Y82_09885	COG0793	Belongs to the peptidase S41A family
C5Y82_09890	COG2226	methyltransferase
C5Y82_09900	COG1876	peptidase activity
C5Y82_09905	COG0813	purine-nucleoside phosphorylase activity
C5Y82_09915	COG0671	phosphoesterase, PA-phosphatase related
C5Y82_09930	COG4479	Belongs to the UPF0346 family
C5Y82_09940	COG1509	lysine 2,3-aminomutase activity
C5Y82_09945	COG3829	transcription factor binding
C5Y82_09950	COG0463	Glycosyl transferase, family 2
C5Y82_09965	COG4641	Protein conserved in bacteria
C5Y82_09975	COG1086	Polysaccharide biosynthesis protein
C5Y82_09980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C5Y82_09985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C5Y82_09990	COG1846	Transcriptional regulator
C5Y82_10010	COG4698	Protein conserved in bacteria
C5Y82_10015	COG2755	lipolytic protein G-D-S-L family
C5Y82_10020	COG1999	signal sequence binding
C5Y82_10035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C5Y82_10040	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C5Y82_10045	COG1272	protein, Hemolysin III
C5Y82_10050	COG0204	Acyl-transferase
C5Y82_10055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C5Y82_10060	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C5Y82_10065	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C5Y82_10075	COG2521	methyltransferase
C5Y82_10075	COG2136	Putative SAM-dependent methyltransferase
C5Y82_10085	COG0129	dihydroxy-acid dehydratase activity
C5Y82_10090	COG1413	lyase activity
C5Y82_10095	COG1418	mRNA catabolic process
C5Y82_10100	COG0386	Belongs to the glutathione peroxidase family
C5Y82_10105	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C5Y82_10110	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C5Y82_10115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C5Y82_10125	COG1278	Cold shock
C5Y82_10140	COG0328	RNA-DNA hybrid ribonuclease activity
C5Y82_10145	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C5Y82_10150	COG0328	RNA-DNA hybrid ribonuclease activity
C5Y82_10160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C5Y82_10170	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C5Y82_10180	COG1755	Isoprenylcysteine carboxyl methyltransferase
C5Y82_10185	COG3424	synthase
C5Y82_10190	COG0726	polysaccharide deacetylase
C5Y82_10195	COG2233	PERMEase
C5Y82_10200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C5Y82_10205	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C5Y82_10210	COG1199	ATP-dependent helicase activity
C5Y82_10225	COG0116	Belongs to the methyltransferase superfamily
C5Y82_10235	COG3599	regulation of cell shape
C5Y82_10240	COG4474	Belongs to the UPF0398 family
C5Y82_10250	COG3359	exonuclease
C5Y82_10255	COG1205	dead DEAH box helicase
C5Y82_10255	COG1111	helicase
C5Y82_10260	COG1902	pentaerythritol trinitrate reductase activity
C5Y82_10265	COG2190	(PTS) system
C5Y82_10270	COG0071	Belongs to the small heat shock protein (HSP20) family
C5Y82_10300	COG3331	DNA recombination
C5Y82_10305	COG4499	WXG100 protein secretion system (Wss), protein YukC
C5Y82_10305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5Y82_10315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C5Y82_10320	COG3935	DnaD domain protein
C5Y82_10325	COG0017	Asparaginyl-tRNA synthetase
C5Y82_10330	COG5353	protein conserved in bacteria
C5Y82_10340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5Y82_10340	COG1199	ATP-dependent helicase activity
C5Y82_10345	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C5Y82_10350	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C5Y82_10355	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C5Y82_10365	COG0617	tRNA 3'-terminal CCA addition
C5Y82_10370	COG0438	transferase activity, transferring glycosyl groups
C5Y82_10375	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C5Y82_10380	COG1803	Methylglyoxal synthase
C5Y82_10385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C5Y82_10390	COG1694	Mazg nucleotide pyrophosphohydrolase
C5Y82_10395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C5Y82_10405	COG4347	Protein of unknown function (DUF1405)
C5Y82_10410	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C5Y82_10410	COG2010	Cytochrome c
C5Y82_10415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C5Y82_10420	COG0723	plastoquinol--plastocyanin reductase activity
C5Y82_10430	COG5582	Belongs to the UPF0302 family
C5Y82_10435	COG0457	Tetratricopeptide repeat
C5Y82_10440	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C5Y82_10445	COG0287	Prephenate dehydrogenase
C5Y82_10450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C5Y82_10455	COG0159	tryptophan synthase activity
C5Y82_10460	COG0133	tryptophan synthase activity
C5Y82_10465	COG0135	phosphoribosylanthranilate isomerase activity
C5Y82_10470	COG0134	indole-3-glycerol-phosphate synthase activity
C5Y82_10475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C5Y82_10485	COG4401	Chorismate mutase type I
C5Y82_10490	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C5Y82_10495	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C5Y82_10500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C5Y82_10505	COG0105	UTP biosynthetic process
C5Y82_10510	COG0142	geranyltranstransferase activity
C5Y82_10515	COG2226	methyltransferase
C5Y82_10520	COG0142	geranyltranstransferase activity
C5Y82_10530	COG0302	gtp cyclohydrolase
C5Y82_10535	COG0776	regulation of translation
C5Y82_10545	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C5Y82_10560	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C5Y82_10565	COG1160	GTP binding
C5Y82_10590	COG1304	FMN binding
C5Y82_10595	COG0539	negative regulation of cytoplasmic translation
C5Y82_10600	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C5Y82_10610	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C5Y82_10615	COG2959	enzyme of heme biosynthesis
C5Y82_10620	COG3773	Cell wall hydrolase
C5Y82_10620	COG3409	Peptidoglycan-binding domain 1 protein
C5Y82_10625	COG2339	peptidase activity
C5Y82_10630	COG0492	ferredoxin-NADP+ reductase activity
C5Y82_10640	COG4862	establishment of competence for transformation
C5Y82_10645	COG1408	metallophosphoesterase
C5Y82_10655	COG1388	LysM domain
C5Y82_10660	COG1266	CAAX protease self-immunity
C5Y82_10665	COG0514	ATP-dependent DNA helicase (RecQ)
C5Y82_10670	COG4955	Helix-turn-helix domain
C5Y82_10675	COG1141	Ferredoxin
C5Y82_10680	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C5Y82_10685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C5Y82_10690	COG5632	N-Acetylmuramoyl-L-alanine amidase
C5Y82_10690	COG3409	Peptidoglycan-binding domain 1 protein
C5Y82_10700	COG1595	DNA-templated transcription, initiation
C5Y82_10705	COG5002	protein histidine kinase activity
C5Y82_10710	COG0745	RESPONSE REGULATOR receiver
C5Y82_10715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C5Y82_10720	COG1333	cytochrome c biogenesis protein
C5Y82_10725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5Y82_10730	COG1187	pseudouridine synthase activity
C5Y82_10735	COG0700	Nucleoside recognition
C5Y82_10740	COG2715	membrane protein required for spore maturation
C5Y82_10745	COG1686	Belongs to the peptidase S11 family
C5Y82_10755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C5Y82_10760	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C5Y82_10770	COG1547	Domain of unknown function (DUF309)
C5Y82_10775	COG0456	acetyltransferase
C5Y82_10780	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C5Y82_10785	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C5Y82_10785	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C5Y82_10790	COG0307	riboflavin synthase, alpha
C5Y82_10815	COG2814	Major facilitator Superfamily
C5Y82_10820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C5Y82_10825	COG4086	secreted protein
C5Y82_10835	COG0019	diaminopimelate decarboxylase activity
C5Y82_10840	COG0697	spore germination
C5Y82_10855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C5Y82_10875	COG1191	sigma factor activity
C5Y82_10880	COG2172	sigma factor antagonist activity
C5Y82_10890	COG1686	Belongs to the peptidase S11 family
C5Y82_10895	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C5Y82_10900	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C5Y82_10905	COG4974	Belongs to the 'phage' integrase family
C5Y82_10915	COG0735	belongs to the Fur family
C5Y82_10920	COG1300	Membrane
C5Y82_10925	COG1404	Belongs to the peptidase S8 family
C5Y82_10935	COG2153	protein acetylation
C5Y82_10940	COG1379	DNA repair
C5Y82_10945	COG0494	nUDIX hydrolase
C5Y82_10950	COG0667	Aldo Keto reductase
C5Y82_10965	COG1073	alpha beta
C5Y82_10970	COG0457	Tetratricopeptide repeat
C5Y82_10980	COG4918	Iron-sulphur cluster biosynthesis
C5Y82_10985	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C5Y82_10985	COG0456	acetyltransferase
C5Y82_10990	COG0456	acetyltransferase
C5Y82_11000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C5Y82_11010	COG2211	Major facilitator Superfamily
C5Y82_11015	COG1072	(Pantothenic acid kinase))
C5Y82_11025	COG0300	oxidoreductase activity
C5Y82_11030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5Y82_11035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C5Y82_11045	COG4187	Peptidase family M20/M25/M40
C5Y82_11050	COG1902	pentaerythritol trinitrate reductase activity
C5Y82_11055	COG0596	Alpha beta hydrolase
C5Y82_11060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5Y82_11070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C5Y82_11075	COG2188	Transcriptional regulator
C5Y82_11080	COG2723	6-phospho-beta-galactosidase activity
C5Y82_11085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5Y82_11090	COG1447	Phosphotransferase system cellobiose-specific component IIA
C5Y82_11095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5Y82_11100	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_11105	COG4975	Glucose uptake
C5Y82_11110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C5Y82_11115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C5Y82_11130	COG0706	membrane insertase activity
C5Y82_11145	COG2195	Cleaves the N-terminal amino acid of tripeptides
C5Y82_11150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C5Y82_11155	COG0346	lactoylglutathione lyase activity
C5Y82_11160	COG1376	ErfK ybiS ycfS ynhG family protein
C5Y82_11165	COG4129	membrane
C5Y82_11170	COG1126	abc transporter atp-binding protein
C5Y82_11175	COG0765	amino acid transport
C5Y82_11180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5Y82_11190	COG1597	lipid kinase activity
C5Y82_11200	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5Y82_11205	COG0022	dehydrogenase e1 component
C5Y82_11210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C5Y82_11215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5Y82_11220	COG3426	butyrate kinase activity
C5Y82_11225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C5Y82_11230	COG0280	phosphate acetyltransferase
C5Y82_11235	COG3829	transcription factor binding
C5Y82_11235	COG3290	protein histidine kinase activity
C5Y82_11245	COG0584	glycerophosphoryl diester phosphodiesterase
C5Y82_11250	COG0457	Tetratricopeptide repeat
C5Y82_11260	COG0745	RESPONSE REGULATOR receiver
C5Y82_11265	COG0750	zinc metalloprotease
C5Y82_11270	COG0497	DNA recombination
C5Y82_11275	COG1438	arginine binding
C5Y82_11280	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C5Y82_11285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C5Y82_11290	COG0142	geranyltranstransferase activity
C5Y82_11295	COG1722	exodeoxyribonuclease VII activity
C5Y82_11300	COG1570	exodeoxyribonuclease VII activity
C5Y82_11305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C5Y82_11310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C5Y82_11315	COG1302	Protein conserved in bacteria
C5Y82_11320	COG0439	Biotin carboxylase
C5Y82_11325	COG0511	ligase activity, forming carbon-carbon bonds
C5Y82_11365	COG3854	ATPases associated with a variety of cellular activities
C5Y82_11375	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C5Y82_11380	COG0006	proline dipeptidase activity
C5Y82_11385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C5Y82_11395	COG3872	metal-dependent enzyme
C5Y82_11405	COG1752	Esterase of the alpha-beta hydrolase superfamily
C5Y82_11410	COG1321	iron dependent repressor
C5Y82_11415	COG0095	Lipoate-protein ligase
C5Y82_11420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5Y82_11425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C5Y82_11430	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C5Y82_11435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C5Y82_11450	COG1396	sequence-specific DNA binding
C5Y82_11460	COG0681	Belongs to the peptidase S26 family
C5Y82_11495	COG4970	Tfp pilus assembly protein FimT
C5Y82_11500	COG4537	Required for transformation and DNA binding
C5Y82_11505	COG1459	type II secretion system
C5Y82_11510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C5Y82_11520	COG1366	Belongs to the anti-sigma-factor antagonist family
C5Y82_11530	COG1393	Belongs to the ArsC family
C5Y82_11545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5Y82_11560	COG0011	TIGRFAM Protein of
C5Y82_11565	COG2814	Major facilitator Superfamily
C5Y82_11570	COG2866	Carboxypeptidase
C5Y82_11575	COG1368	sulfuric ester hydrolase activity
C5Y82_11580	COG1940	carbohydrate kinase activity
C5Y82_11585	COG4483	Protein conserved in bacteria
C5Y82_11590	COG0457	Tetratricopeptide repeat
C5Y82_11590	COG0705	Rhomboid family
C5Y82_11595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C5Y82_11600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C5Y82_11610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C5Y82_11615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C5Y82_11620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C5Y82_11625	COG0581	inorganic phosphate transmembrane transporter activity
C5Y82_11630	COG0573	inorganic phosphate transmembrane transporter activity
C5Y82_11635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C5Y82_11645	COG0477	Major facilitator Superfamily
C5Y82_11650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C5Y82_11655	COG2839	Protein conserved in bacteria
C5Y82_11660	COG5521	maltodextrose utilization protein MalA
C5Y82_11665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5Y82_11670	COG1388	LysM domain
C5Y82_11675	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C5Y82_11680	COG4709	membrane
C5Y82_11685	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C5Y82_11690	COG1940	carbohydrate kinase activity
C5Y82_11700	COG0735	belongs to the Fur family
C5Y82_11705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C5Y82_11710	COG1121	(ABC) transporter
C5Y82_11715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C5Y82_11725	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C5Y82_11730	COG0513	Belongs to the DEAD box helicase family
C5Y82_11740	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C5Y82_11745	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C5Y82_11750	COG2384	SAM-dependent methyltransferase
C5Y82_11755	COG2010	Cytochrome c
C5Y82_11760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C5Y82_11765	COG0358	DNA primase activity
C5Y82_11770	COG1671	Belongs to the UPF0178 family
C5Y82_11775	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C5Y82_11780	COG0517	IMP dehydrogenase activity
C5Y82_11785	COG0751	glycine-tRNA ligase activity
C5Y82_11790	COG0752	glycyl-tRNA synthetase alpha subunit
C5Y82_11795	COG1381	Involved in DNA repair and RecF pathway recombination
C5Y82_11805	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C5Y82_11810	COG0295	cytidine deaminase activity
C5Y82_11815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C5Y82_11820	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C5Y82_11825	COG1480	7TM receptor with intracellular HD hydrolase
C5Y82_11830	COG1702	phosphate starvation-inducible protein PhoH
C5Y82_11835	COG0561	phosphatase activity
C5Y82_11850	COG4864	UPF0365 protein
C5Y82_11855	COG1030	water channel activity
C5Y82_11860	COG1610	YqeY-like protein
C5Y82_11865	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C5Y82_11870	COG1283	sodium-dependent phosphate transmembrane transporter activity
C5Y82_11875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C5Y82_11880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C5Y82_11885	COG2264	protein methyltransferase activity
C5Y82_11890	COG0484	heat shock protein binding
C5Y82_11895	COG0443	Heat shock 70 kDa protein
C5Y82_11900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C5Y82_11905	COG1420	regulation of RNA biosynthetic process
C5Y82_11910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C5Y82_11915	COG0481	GTPase activity
C5Y82_11925	COG0860	N-Acetylmuramoyl-L-alanine amidase
C5Y82_11930	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C5Y82_11935	COG0268	Binds directly to 16S ribosomal RNA
C5Y82_11940	COG1466	dna polymerase III delta subunit
C5Y82_11950	COG0658	competence protein
C5Y82_11950	COG2333	competence protein COMEC
C5Y82_11955	COG2131	deaminase
C5Y82_11960	COG1555	photosystem II stabilization
C5Y82_11965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C5Y82_11970	COG2226	methyltransferase
C5Y82_11975	COG0799	negative regulation of ribosome biogenesis
C5Y82_11980	COG1713	HD superfamily hydrolase involved in NAD metabolism
C5Y82_11985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C5Y82_11990	COG1534	Rna-binding protein
C5Y82_11995	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C5Y82_12000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C5Y82_12005	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C5Y82_12015	COG2755	lipolytic protein G-D-S-L family
C5Y82_12025	COG0457	Tetratricopeptide repeat
C5Y82_12055	COG0726	polysaccharide deacetylase
C5Y82_12090	COG2160	L-arabinose isomerase activity
C5Y82_12105	COG1609	Transcriptional regulator
C5Y82_12115	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C5Y82_12120	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C5Y82_12125	COG1733	regulation of RNA biosynthetic process
C5Y82_12145	COG3209	COG3209 Rhs family protein
C5Y82_12150	COG2602	Beta-lactamase
C5Y82_12155	COG1960	acyl-CoA dehydrogenase activity
C5Y82_12160	COG1126	abc transporter atp-binding protein
C5Y82_12165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5Y82_12170	COG0765	amino acid transport
C5Y82_12180	COG3546	catalase activity
C5Y82_12185	COG1063	alcohol dehydrogenase
C5Y82_12195	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_12205	COG1115	amino acid carrier protein
C5Y82_12210	COG0583	DNA-binding transcription factor activity
C5Y82_12215	COG1132	(ABC) transporter
C5Y82_12220	COG0454	-acetyltransferase
C5Y82_12225	COG1063	alcohol dehydrogenase
C5Y82_12230	COG2226	methyltransferase
C5Y82_12250	COG0626	cystathionine gamma-synthase activity
C5Y82_12255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C5Y82_12260	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C5Y82_12265	COG2226	methyltransferase
C5Y82_12280	COG0768	penicillin binding
C5Y82_12285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C5Y82_12290	COG0572	uridine kinase
C5Y82_12310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C5Y82_12315	COG0183	Belongs to the thiolase family
C5Y82_12320	COG0318	PFAM AMP-dependent synthetase and ligase
C5Y82_12325	COG1268	BioY protein
C5Y82_12330	COG3906	Belongs to the UPF0473 family
C5Y82_12335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C5Y82_12340	COG4472	Bacterial protein of unknown function (DUF965)
C5Y82_12345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C5Y82_12350	COG0628	permease
C5Y82_12355	COG1126	abc transporter atp-binding protein
C5Y82_12360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5Y82_12365	COG0765	amino acid transport
C5Y82_12370	COG0765	amino acid transport
C5Y82_12390	COG3881	PFAM PRC-barrel domain
C5Y82_12395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C5Y82_12400	COG0457	Tetratricopeptide repeat
C5Y82_12405	COG0482	sulfurtransferase activity
C5Y82_12410	COG1104	cysteine desulfurase activity
C5Y82_12415	COG1959	2 iron, 2 sulfur cluster binding
C5Y82_12420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C5Y82_12430	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C5Y82_12445	COG0124	histidyl-tRNA synthetase
C5Y82_12450	COG0860	N-Acetylmuramoyl-L-alanine amidase
C5Y82_12450	COG3103	Sh3 type 3 domain protein
C5Y82_12450	COG4991	sh3 domain protein
C5Y82_12455	COG1490	D-aminoacyl-tRNA deacylase activity
C5Y82_12460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C5Y82_12465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C5Y82_12470	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C5Y82_12470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C5Y82_12475	COG5416	Lipopolysaccharide assembly protein A domain
C5Y82_12485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5Y82_12485	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5Y82_12495	COG2244	polysaccharide biosynthetic process
C5Y82_12500	COG2323	membrane
C5Y82_12510	COG1862	Preprotein translocase
C5Y82_12515	COG0343	queuine tRNA-ribosyltransferase activity
C5Y82_12520	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C5Y82_12530	COG2255	four-way junction helicase activity
C5Y82_12535	COG0632	four-way junction helicase activity
C5Y82_12545	COG2112	serine threonine protein kinase
C5Y82_12555	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C5Y82_12570	COG1388	LysM domain
C5Y82_12575	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C5Y82_12580	COG0157	Belongs to the NadC ModD family
C5Y82_12585	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C5Y82_12590	COG1104	cysteine desulfurase activity
C5Y82_12595	COG1827	regulation of RNA biosynthetic process
C5Y82_12600	COG0077	Prephenate dehydratase
C5Y82_12605	COG4492	Belongs to the UPF0735 family
C5Y82_12610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C5Y82_12615	COG3290	protein histidine kinase activity
C5Y82_12620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C5Y82_12625	COG2868	ribosomal protein
C5Y82_12630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C5Y82_12635	COG1994	Peptidase M50
C5Y82_12640	COG0739	heme binding
C5Y82_12645	COG2894	cell division
C5Y82_12650	COG0850	regulation of cytokinetic process
C5Y82_12655	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C5Y82_12660	COG1792	Involved in formation and maintenance of cell shape
C5Y82_12665	COG1077	Cell shape determining protein MreB Mrl
C5Y82_12670	COG2003	Belongs to the UPF0758 family
C5Y82_12675	COG0424	maF-like protein
C5Y82_12685	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C5Y82_12690	COG0285	dihydrofolate synthase activity
C5Y82_12695	COG0525	valine-tRNA ligase activity
C5Y82_12705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C5Y82_12710	COG1388	LysM domain
C5Y82_12715	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C5Y82_12720	COG0113	porphobilinogen synthase activity
C5Y82_12725	COG1587	Uroporphyrinogen-III synthase
C5Y82_12730	COG0181	hydroxymethylbilane synthase activity
C5Y82_12735	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C5Y82_12740	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C5Y82_12750	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C5Y82_12755	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C5Y82_12760	COG1067	ATP-dependent peptidase activity
C5Y82_12760	COG0470	DNA polymerase III
C5Y82_12765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C5Y82_12770	COG0544	peptidyl-prolyl cis-trans isomerase activity
C5Y82_12775	COG1477	protein flavinylation
C5Y82_12775	COG0457	Tetratricopeptide repeat
C5Y82_12780	COG0066	3-isopropylmalate dehydratase activity
C5Y82_12785	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C5Y82_12790	COG0473	3-isopropylmalate dehydrogenase activity
C5Y82_12795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C5Y82_12800	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C5Y82_12805	COG0440	acetolactate synthase activity
C5Y82_12810	COG0028	Belongs to the TPP enzyme family
C5Y82_12815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5Y82_12820	COG2706	6-phosphogluconolactonase activity
C5Y82_12825	COG3339	Conserved Protein
C5Y82_12830	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C5Y82_12835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5Y82_12840	COG1696	Membrane protein involved in D-alanine export
C5Y82_12855	COG0346	lactoylglutathione lyase activity
C5Y82_12885	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_12895	COG0622	Phosphoesterase
C5Y82_12900	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C5Y82_12905	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C5Y82_12910	COG5401	PFAM Sporulation and spore germination
C5Y82_12915	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C5Y82_12920	COG1846	Transcriptional regulator
C5Y82_12925	COG2197	response regulator
C5Y82_12930	COG2851	Citrate transporter
C5Y82_12935	COG0583	DNA-binding transcription factor activity
C5Y82_12940	COG2828	Protein conserved in bacteria
C5Y82_12950	COG0824	Thioesterase
C5Y82_12955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C5Y82_12960	COG1053	succinate dehydrogenase
C5Y82_12965	COG2009	succinate dehydrogenase
C5Y82_12970	COG1719	4-vinyl reductase, 4VR
C5Y82_12975	COG0527	aspartate kinase activity
C5Y82_12985	COG0322	excinuclease ABC activity
C5Y82_12990	COG3118	belongs to the thioredoxin family
C5Y82_12995	COG3534	alpha-L-arabinofuranosidase
C5Y82_13000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C5Y82_13005	COG2086	electron transfer activity
C5Y82_13010	COG1024	Enoyl-CoA hydratase
C5Y82_13015	COG1309	transcriptional regulator
C5Y82_13020	COG0318	PFAM AMP-dependent synthetase and ligase
C5Y82_13030	COG3766	membrane
C5Y82_13035	COG1193	negative regulation of DNA recombination
C5Y82_13040	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C5Y82_13040	COG1796	DNA polymerase
C5Y82_13045	COG1286	toxin biosynthetic process
C5Y82_13050	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C5Y82_13055	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C5Y82_13060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5Y82_13060	COG0072	phenylalanine-tRNA ligase activity
C5Y82_13065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C5Y82_13070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5Y82_13080	COG1966	Carbon starvation protein
C5Y82_13085	COG1363	Peptidase, m42
C5Y82_13095	COG3326	Membrane
C5Y82_13100	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C5Y82_13105	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C5Y82_13110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C5Y82_13115	COG1346	cytolysis
C5Y82_13125	COG3279	Response regulator of the LytR AlgR family
C5Y82_13130	COG3275	phosphorelay sensor kinase activity
C5Y82_13145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C5Y82_13155	COG0398	Pfam SNARE associated Golgi protein
C5Y82_13160	COG1484	DNA-dependent DNA replication
C5Y82_13165	COG3611	Membrane attachment protein
C5Y82_13170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C5Y82_13180	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C5Y82_13185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C5Y82_13190	COG0237	dephospho-CoA kinase activity
C5Y82_13200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C5Y82_13205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C5Y82_13205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C5Y82_13210	COG5002	protein histidine kinase activity
C5Y82_13215	COG0745	RESPONSE REGULATOR receiver
C5Y82_13220	COG0039	L-malate dehydrogenase activity
C5Y82_13225	COG0538	isocitrate dehydrogenase activity
C5Y82_13230	COG0372	Belongs to the citrate synthase family
C5Y82_13235	COG2707	UPF0756 membrane protein
C5Y82_13240	COG0628	permease
C5Y82_13245	COG3030	protein affecting phage T7 exclusion by the F plasmid
C5Y82_13255	COG0205	6-phosphofructokinase activity
C5Y82_13260	COG0825	malonyl-CoA metabolic process
C5Y82_13265	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C5Y82_13270	COG0281	malic enzyme
C5Y82_13275	COG0587	DNA-directed DNA polymerase activity
C5Y82_13295	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C5Y82_13305	COG4109	DRTGG domain
C5Y82_13310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C5Y82_13315	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_13325	COG0165	Argininosuccinate lyase
C5Y82_13330	COG0137	argininosuccinate synthase activity
C5Y82_13335	COG0521	Mo-molybdopterin cofactor biosynthetic process
C5Y82_13340	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C5Y82_13345	COG0827	DNA restriction-modification system
C5Y82_13350	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C5Y82_13355	COG3874	Sporulation protein YtfJ
C5Y82_13365	COG1714	RDD family
C5Y82_13370	COG0616	signal peptide processing
C5Y82_13375	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C5Y82_13385	COG3239	Fatty acid desaturase
C5Y82_13390	COG4585	Histidine kinase
C5Y82_13395	COG2197	response regulator
C5Y82_13400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5Y82_13405	COG0745	RESPONSE REGULATOR receiver
C5Y82_13410	COG2205	protein histidine kinase activity
C5Y82_13415	COG1136	(ABC) transporter
C5Y82_13420	COG0577	efflux transmembrane transporter activity
C5Y82_13425	COG0402	S-adenosylhomocysteine deaminase activity
C5Y82_13430	COG2249	NAD(P)H dehydrogenase (quinone) activity
C5Y82_13445	COG1279	arginine transmembrane transporter activity
C5Y82_13450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5Y82_13460	COG0301	tRNA thio-modification
C5Y82_13465	COG1104	cysteine desulfurase activity
C5Y82_13470	COG1114	Component of the transport system for branched-chain amino acids
C5Y82_13475	COG1114	Component of the transport system for branched-chain amino acids
C5Y82_13480	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C5Y82_13485	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C5Y82_13490	COG1309	transcriptional regulator
C5Y82_13495	COG1956	GAF domain-containing protein
C5Y82_13500	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C5Y82_13510	COG1335	isochorismatase
C5Y82_13520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C5Y82_13525	COG2329	Antibiotic biosynthesis monooxygenase
C5Y82_13530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C5Y82_13535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5Y82_13540	COG0454	-acetyltransferase
C5Y82_13545	COG0517	IMP dehydrogenase activity
C5Y82_13550	COG0123	including yeast histone deacetylase and acetoin utilization protein
C5Y82_13555	COG1609	Transcriptional regulator
C5Y82_13560	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C5Y82_13560	COG1605	Chorismate mutase
C5Y82_13565	COG3118	belongs to the thioredoxin family
C5Y82_13570	COG4980	gas vesicle protein
C5Y82_13575	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C5Y82_13580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C5Y82_13585	COG1674	ftsk spoiiie
C5Y82_13590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5Y82_13595	COG4848	Belongs to the UPF0354 family
C5Y82_13600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5Y82_13620	COG1363	Peptidase, m42
C5Y82_13625	COG5584	Small secreted protein
C5Y82_13630	COG0281	malic enzyme
C5Y82_13635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5Y82_13640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C5Y82_13650	COG0510	thiamine kinase activity
C5Y82_13655	COG1597	lipid kinase activity
C5Y82_13665	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C5Y82_13670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C5Y82_13675	COG3340	Belongs to the peptidase S51 family
C5Y82_13680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5Y82_13685	COG2252	PERMEase
C5Y82_13690	COG1349	DNA-binding transcription factor activity
C5Y82_13695	COG1187	pseudouridine synthase activity
C5Y82_13700	COG2244	polysaccharide biosynthetic process
C5Y82_13705	COG2081	HI0933 family
C5Y82_13715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C5Y82_13725	COG3196	Protein conserved in bacteria
C5Y82_13735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5Y82_13740	COG5578	integral membrane protein
C5Y82_13745	COG0673	inositol 2-dehydrogenase activity
C5Y82_13750	COG1653	transport
C5Y82_13755	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C5Y82_13760	COG4209	transmembrane transport
C5Y82_13765	COG2207	Transcriptional regulator
C5Y82_13770	COG1733	regulation of RNA biosynthetic process
C5Y82_13775	COG2814	Major facilitator Superfamily
C5Y82_13780	COG0656	L-ascorbic acid biosynthetic process
C5Y82_13785	COG1653	transport
C5Y82_13790	COG0395	ABC-type sugar transport system, permease component
C5Y82_13795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5Y82_13800	COG1073	alpha beta
C5Y82_13805	COG0495	leucyl-tRNA aminoacylation
C5Y82_13815	COG2202	Pas domain
C5Y82_13815	COG1366	Belongs to the anti-sigma-factor antagonist family
C5Y82_13820	COG2433	Pfam Transposase IS66
C5Y82_13825	COG0577	efflux transmembrane transporter activity
C5Y82_13830	COG1136	(ABC) transporter
C5Y82_13840	COG1131	(ABC) transporter
C5Y82_13845	COG1725	Transcriptional regulator
C5Y82_13860	COG1242	4 iron, 4 sulfur cluster binding
C5Y82_13865	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C5Y82_13875	COG2267	carboxylic ester hydrolase activity
C5Y82_13880	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C5Y82_13885	COG0367	asparagine synthase
C5Y82_13890	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C5Y82_13895	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C5Y82_13905	COG1506	peptidase
C5Y82_13910	COG1233	COG1233 Phytoene dehydrogenase and related
C5Y82_13930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C5Y82_13935	COG1116	anion transmembrane transporter activity
C5Y82_13940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5Y82_13945	COG0494	nUDIX hydrolase
C5Y82_13950	COG2310	stress, protein
C5Y82_13965	COG4824	toxin secretion phage lysis holin
C5Y82_13975	COG0783	Belongs to the Dps family
C5Y82_13990	COG1854	S-ribosylhomocysteine lyase activity
C5Y82_13995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C5Y82_14000	COG0288	reversible hydration of carbon dioxide
C5Y82_14005	COG3443	Belongs to the bacterial solute-binding protein 9 family
C5Y82_14005	COG0803	Belongs to the bacterial solute-binding protein 9 family
C5Y82_14020	COG1271	oxidase subunit
C5Y82_14025	COG1294	oxidase, subunit
C5Y82_14040	COG4948	Mandelate Racemase Muconate Lactonizing
C5Y82_14045	COG0318	PFAM AMP-dependent synthetase and ligase
C5Y82_14050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C5Y82_14055	COG0596	Alpha beta hydrolase
C5Y82_14060	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C5Y82_14065	COG1169	isochorismate synthase
C5Y82_14070	COG1575	Belongs to the MenA family. Type 1 subfamily
C5Y82_14075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C5Y82_14205	COG3859	Proton-coupled thiamine transporter YuaJ
C5Y82_14215	COG1247	-acetyltransferase
C5Y82_14220	COG3339	Conserved Protein
C5Y82_14225	COG0772	Belongs to the SEDS family
C5Y82_14230	COG0772	Belongs to the SEDS family
C5Y82_14235	COG2268	Band 7 protein
C5Y82_14240	COG1585	Membrane protein implicated in regulation of membrane protease activity
C5Y82_14245	COG2318	DinB family
C5Y82_14250	COG1454	alcohol dehydrogenase
C5Y82_14260	COG1510	regulation of RNA biosynthetic process
C5Y82_14330	COG1876	peptidase activity
C5Y82_14335	COG3594	Acyltransferase
C5Y82_14370	COG3778	Protein conserved in bacteria
C5Y82_14375	COG3299	homolog of phage Mu protein gp47
C5Y82_14380	COG3628	GPW Gp25 family protein
C5Y82_14390	COG4193	domain, Protein
C5Y82_14395	COG1652	LysM domain
C5Y82_14400	COG3953	SLT domain
C5Y82_14400	COG5280	Phage tail tape measure protein TP901
C5Y82_14400	COG5280	Phage tail tape measure protein TP901
C5Y82_14400	COG3953	SLT domain
C5Y82_14455	COG4653	Phage capsid family
C5Y82_14460	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C5Y82_14465	COG5518	Phage portal protein
C5Y82_14470	COG1783	phage Terminase large subunit
C5Y82_14475	COG5484	DNA packaging
C5Y82_14480	COG1595	DNA-templated transcription, initiation
C5Y82_14490	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C5Y82_14505	COG1396	sequence-specific DNA binding
C5Y82_14515	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C5Y82_14530	COG1968	undecaprenyl-diphosphatase activity
C5Y82_14535	COG0628	permease
C5Y82_14545	COG0673	inositol 2-dehydrogenase activity
C5Y82_14550	COG0693	protein deglycase activity
C5Y82_14555	COG0840	transmembrane signaling receptor activity
C5Y82_14560	COG0840	transmembrane signaling receptor activity
C5Y82_14565	COG0840	transmembrane signaling receptor activity
C5Y82_14570	COG0840	transmembrane signaling receptor activity
C5Y82_14585	COG2070	2-Nitropropane dioxygenase
C5Y82_14590	COG0432	Pfam Uncharacterised protein family UPF0047
C5Y82_14595	COG1253	flavin adenine dinucleotide binding
C5Y82_14600	COG2738	Putative neutral zinc metallopeptidase
C5Y82_14610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C5Y82_14625	COG0166	Belongs to the GPI family
C5Y82_14630	COG1979	alcohol dehydrogenase
C5Y82_14635	COG1979	alcohol dehydrogenase
C5Y82_14640	COG2155	Conserved Protein
C5Y82_14645	COG1098	S1 RNA binding domain
C5Y82_14650	COG0436	Aminotransferase
C5Y82_14655	COG1522	sequence-specific DNA binding
C5Y82_14660	COG2267	carboxylic ester hydrolase activity
C5Y82_14670	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C5Y82_14675	COG2205	protein histidine kinase activity
C5Y82_14690	COG5018	Exonuclease
C5Y82_14695	COG2814	Major facilitator Superfamily
C5Y82_14700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5Y82_14705	COG3011	Protein conserved in bacteria
C5Y82_14715	COG3290	protein histidine kinase activity
C5Y82_14720	COG4565	transcriptional regulatory protein
C5Y82_14745	COG3493	citrate carrier protein
C5Y82_14755	COG2111	Na H antiporter
C5Y82_14755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C5Y82_14760	COG2111	Na H antiporter
C5Y82_14765	COG1006	Multisubunit Na H antiporter MnhC subunit
C5Y82_14770	COG0651	ATP synthesis coupled electron transport
C5Y82_14775	COG1863	multisubunit Na H antiporter MnhE subunit
C5Y82_14780	COG2212	antiporter activity
C5Y82_14785	COG1320	monovalent cation:proton antiporter activity
C5Y82_14790	COG2050	protein possibly involved in aromatic compounds catabolism
C5Y82_14795	COG2197	response regulator
C5Y82_14800	COG4585	Histidine kinase
C5Y82_14810	COG0142	geranyltranstransferase activity
C5Y82_14825	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C5Y82_14830	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C5Y82_14835	COG1335	isochorismatase
C5Y82_14840	COG5506	Protein of unknown function (DUF1694)
C5Y82_14860	COG0628	permease
C5Y82_14875	COG1418	mRNA catabolic process
C5Y82_14880	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_14890	COG1511	domain protein
C5Y82_14895	COG0433	COG0433 Predicted ATPase
C5Y82_14895	COG1674	ftsk spoiiie
C5Y82_14900	COG4499	WXG100 protein secretion system (Wss), protein YukC
C5Y82_14905	COG5417	Belongs to the EsaB family
C5Y82_14910	COG4842	Belongs to the WXG100 family
C5Y82_14915	COG2508	Transcriptional regulator
C5Y82_14915	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C5Y82_14920	COG0686	Belongs to the AlaDH PNT family
C5Y82_14925	COG1268	BioY protein
C5Y82_14930	COG4326	sporulation control protein
C5Y82_14935	COG2056	Na+-H+ antiporter family
C5Y82_14940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C5Y82_14945	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C5Y82_14950	COG3584	3D domain protein
C5Y82_14960	COG1252	NADH dehydrogenase
C5Y82_14965	COG0492	ferredoxin-NADP+ reductase activity
C5Y82_14980	COG0316	Belongs to the HesB IscA family
C5Y82_14985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C5Y82_14990	COG4844	belongs to the
C5Y82_14995	COG1252	NADH dehydrogenase
C5Y82_15005	COG4837	Protein of unknown function (DUF1462)
C5Y82_15010	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C5Y82_15015	COG1506	peptidase
C5Y82_15015	COG0823	Involved in the tonB-independent uptake of proteins
C5Y82_15015	COG4946	Tricorn protease homolog
C5Y82_15020	COG0083	homoserine kinase activity
C5Y82_15025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C5Y82_15030	COG0460	homoserine dehydrogenase
C5Y82_15035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5Y82_15040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C5Y82_15045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C5Y82_15050	COG0647	UMP catabolic process
C5Y82_15055	COG2445	Protein of unknown function DUF86
C5Y82_15060	COG4470	Protein conserved in bacteria
C5Y82_15070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C5Y82_15075	COG0739	heme binding
C5Y82_15085	COG3377	Domain of unknown function (DUF1805)
C5Y82_15090	COG0737	Belongs to the 5'-nucleotidase family
C5Y82_15095	COG1801	Protein of unknown function DUF72
C5Y82_15100	COG2508	Transcriptional regulator
C5Y82_15105	COG2140	Oxalate decarboxylase
C5Y82_15110	COG2814	Major facilitator Superfamily
C5Y82_15115	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C5Y82_15120	COG2356	endonuclease I
C5Y82_15130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5Y82_15135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5Y82_15140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5Y82_15160	COG5002	protein histidine kinase activity
C5Y82_15160	COG0642	Histidine kinase
C5Y82_15165	COG0745	RESPONSE REGULATOR receiver
C5Y82_15170	COG2311	Membrane
C5Y82_15180	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C5Y82_15195	COG0719	Fe-S assembly protein
C5Y82_15200	COG0822	iron-sulfur transferase activity
C5Y82_15205	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C5Y82_15210	COG0719	Fe-S assembly protein
C5Y82_15215	COG0396	ATPase activity
C5Y82_15220	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C5Y82_15230	COG1464	Belongs to the NlpA lipoprotein family
C5Y82_15235	COG2011	ABC-type metal ion transport system permease component
C5Y82_15240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C5Y82_15250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5Y82_15255	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C5Y82_15265	COG0509	glycine decarboxylation via glycine cleavage system
C5Y82_15270	COG1393	Belongs to the ArsC family
C5Y82_15275	COG1960	acyl-CoA dehydrogenase activity
C5Y82_15280	COG0183	Belongs to the thiolase family
C5Y82_15285	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5Y82_15285	COG1024	Enoyl-CoA hydratase
C5Y82_15300	COG5577	PFAM Coat F domain
C5Y82_15310	COG1120	ATPase activity
C5Y82_15320	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_15325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5Y82_15330	COG0745	RESPONSE REGULATOR receiver
C5Y82_15335	COG2205	protein histidine kinase activity
C5Y82_15335	COG2770	Histidine kinase
C5Y82_15340	COG1309	transcriptional regulator
C5Y82_15345	COG0114	fumarate hydratase activity
C5Y82_15355	COG0697	spore germination
C5Y82_15360	COG0814	amino acid
C5Y82_15375	COG2197	response regulator
C5Y82_15380	COG4585	Histidine kinase
C5Y82_15385	COG4758	membrane
C5Y82_15395	COG1842	Phage shock protein A
C5Y82_15400	COG4758	membrane
C5Y82_15405	COG2096	Adenosyltransferase
C5Y82_15410	COG1120	ATPase activity
C5Y82_15415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5Y82_15420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5Y82_15430	COG2721	sulfolactate sulfo-lyase activity
C5Y82_15435	COG0246	Mannitol dehydrogenase
C5Y82_15440	COG1609	Transcriptional regulator
C5Y82_15445	COG1904	glucuronate isomerase
C5Y82_15450	COG2205	protein histidine kinase activity
C5Y82_15455	COG0745	RESPONSE REGULATOR receiver
C5Y82_15460	COG1120	ATPase activity
C5Y82_15465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5Y82_15470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5Y82_15475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5Y82_15480	COG0531	amino acid
C5Y82_15500	COG1988	membrane-bound metal-dependent
C5Y82_15505	COG1368	sulfuric ester hydrolase activity
C5Y82_15510	COG0725	ABC transporter, periplasmic molybdate-binding protein
C5Y82_15515	COG4149	molybdate abc transporter
C5Y82_15520	COG0656	L-ascorbic acid biosynthetic process
C5Y82_15525	COG1940	carbohydrate kinase activity
C5Y82_15530	COG0025	NhaP-type Na H and K H
C5Y82_15535	COG2860	membrane
C5Y82_15540	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C5Y82_15545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C5Y82_15550	COG2217	Heavy metal translocating P-type atpase
C5Y82_15555	COG1121	(ABC) transporter
C5Y82_15560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C5Y82_15565	COG0803	Belongs to the bacterial solute-binding protein 9 family
C5Y82_15575	COG3226	Transcriptional regulator
C5Y82_15580	COG0784	Response regulator, receiver
C5Y82_15585	COG4191	Histidine kinase
C5Y82_15590	COG1027	Aspartate ammonia-lyase
C5Y82_15600	COG2217	Heavy metal translocating P-type atpase
C5Y82_15605	COG2608	mercury ion transmembrane transporter activity
C5Y82_15610	COG1937	Protein conserved in bacteria
C5Y82_15620	COG0745	RESPONSE REGULATOR receiver
C5Y82_15620	COG3706	GGDEF domain
C5Y82_15645	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C5Y82_15650	COG0557	exoribonuclease II activity
C5Y82_15655	COG1647	Serine aminopeptidase, S33
C5Y82_15660	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C5Y82_15665	COG2002	toxin-antitoxin pair type II binding
C5Y82_15670	COG1476	TRANSCRIPTIONal
C5Y82_15675	COG1396	sequence-specific DNA binding
C5Y82_15680	COG1396	sequence-specific DNA binding
C5Y82_15685	COG1733	regulation of RNA biosynthetic process
C5Y82_15690	COG1174	glycine betaine transport
C5Y82_15695	COG1732	Glycine betaine
C5Y82_15700	COG1174	glycine betaine transport
C5Y82_15705	COG1125	glycine betaine transport
C5Y82_15705	COG0517	IMP dehydrogenase activity
C5Y82_15710	COG1510	regulation of RNA biosynthetic process
C5Y82_15715	COG2095	MarC family integral membrane protein
C5Y82_15725	COG0456	acetyltransferase
C5Y82_15745	COG1131	(ABC) transporter
C5Y82_15755	COG0148	phosphopyruvate hydratase activity
C5Y82_15760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C5Y82_15765	COG0149	triose-phosphate isomerase activity
C5Y82_15770	COG0126	phosphoglycerate kinase activity
C5Y82_15775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C5Y82_15780	COG2390	Transcriptional regulator
C5Y82_15785	COG0833	amino acid
C5Y82_15790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C5Y82_15795	COG3829	transcription factor binding
C5Y82_15800	COG2186	Transcriptional regulator
C5Y82_15805	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C5Y82_15815	COG0534	Mate efflux family protein
C5Y82_15820	COG4608	Belongs to the ABC transporter superfamily
C5Y82_15825	COG0444	Belongs to the ABC transporter superfamily
C5Y82_15830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5Y82_15835	COG0601	transmembrane transport
C5Y82_15840	COG0747	negative chemotaxis
C5Y82_15845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5Y82_15850	COG0110	maltose O-acetyltransferase activity
C5Y82_15855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C5Y82_15860	COG2244	polysaccharide biosynthetic process
C5Y82_15865	COG5039	Polysaccharide pyruvyl transferase
C5Y82_15870	COG1216	Glycosyl transferase, family 2
C5Y82_15880	COG0438	transferase activity, transferring glycosyl groups
C5Y82_15885	COG1215	transferase activity, transferring glycosyl groups
C5Y82_15890	COG0438	transferase activity, transferring glycosyl groups
C5Y82_15895	COG1086	Polysaccharide biosynthesis protein
C5Y82_15900	COG0489	protein tyrosine kinase activity
C5Y82_15910	COG1396	sequence-specific DNA binding
C5Y82_15920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5Y82_15925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5Y82_15930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5Y82_15935	COG0726	polysaccharide deacetylase
C5Y82_15945	COG1124	(ABC) transporter
C5Y82_15960	COG0601	transmembrane transport
C5Y82_15965	COG0747	negative chemotaxis
C5Y82_15975	COG1819	glycosyl
C5Y82_16000	COG0740	serine-type endopeptidase activity
C5Y82_16005	COG1611	Belongs to the LOG family
C5Y82_16010	COG1694	Mazg nucleotide pyrophosphohydrolase
C5Y82_16015	COG0659	secondary active sulfate transmembrane transporter activity
C5Y82_16020	COG0288	reversible hydration of carbon dioxide
C5Y82_16025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5Y82_16035	COG1301	dicarboxylic acid transport
C5Y82_16050	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C5Y82_16055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5Y82_16060	COG1481	regulation of sporulation
C5Y82_16065	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C5Y82_16070	COG1660	Displays ATPase and GTPase activities
C5Y82_16075	COG1051	belongs to the nudix hydrolase family
C5Y82_16080	COG0492	ferredoxin-NADP+ reductase activity
C5Y82_16085	COG3883	PFAM NLP P60 protein
C5Y82_16085	COG0791	NLP P60 protein
C5Y82_16090	COG0457	Tetratricopeptide repeat
C5Y82_16095	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C5Y82_16095	COG0140	phosphoribosyl-ATP diphosphatase activity
C5Y82_16100	COG0107	imidazoleglycerol-phosphate synthase activity
C5Y82_16105	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C5Y82_16110	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C5Y82_16115	COG0131	Imidazoleglycerol-phosphate dehydratase
C5Y82_16120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C5Y82_16125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C5Y82_16130	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C5Y82_16135	COG4990	cell redox homeostasis
C5Y82_16145	COG2910	NAD(P)H-binding
C5Y82_16150	COG1959	2 iron, 2 sulfur cluster binding
C5Y82_16155	COG0110	maltose O-acetyltransferase activity
C5Y82_16160	COG0546	phosphoglycolate phosphatase activity
C5Y82_16165	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C5Y82_16170	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C5Y82_16175	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C5Y82_16180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C5Y82_16185	COG0363	glucosamine-6-phosphate deaminase activity
C5Y82_16195	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C5Y82_16200	COG1950	PFAM Membrane protein of
C5Y82_16205	COG1983	PspC domain protein
C5Y82_16210	COG3595	metallopeptidase activity
C5Y82_16225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C5Y82_16235	COG4897	Protein conserved in bacteria
C5Y82_16240	COG0574	Belongs to the PEP-utilizing enzyme family
C5Y82_16240	COG3848	Pyruvate phosphate dikinase
C5Y82_16245	COG1309	transcriptional regulator
C5Y82_16250	COG2814	Major facilitator Superfamily
C5Y82_16260	COG0745	RESPONSE REGULATOR receiver
C5Y82_16265	COG5002	protein histidine kinase activity
C5Y82_16270	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C5Y82_16275	COG0463	Glycosyl transferase, family 2
C5Y82_16280	COG1113	amino acid transport
C5Y82_16285	COG0778	Nitroreductase
C5Y82_16290	COG1733	regulation of RNA biosynthetic process
C5Y82_16295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5Y82_16305	COG3409	Peptidoglycan-binding domain 1 protein
C5Y82_16305	COG0793	Belongs to the peptidase S41A family
C5Y82_16310	COG0730	response to heat
C5Y82_16315	COG3883	PFAM NLP P60 protein
C5Y82_16315	COG0791	NLP P60 protein
C5Y82_16320	COG2177	Part of the ABC transporter FtsEX involved in
C5Y82_16325	COG2884	Cell division ATP-binding protein ftsE
C5Y82_16330	COG2010	Cytochrome c
C5Y82_16335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C5Y82_16355	COG0653	protein targeting
C5Y82_16360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C5Y82_16365	COG0840	transmembrane signaling receptor activity
C5Y82_16380	COG1516	flagellar protein fliS
C5Y82_16385	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C5Y82_16390	COG1334	flagellar protein FlaG
C5Y82_16395	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C5Y82_16400	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
C5Y82_16410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5Y82_16415	COG4786	Flagellar basal body rod
C5Y82_16415	COG1256	bacterial-type flagellum assembly
C5Y82_16420	COG3418	PFAM FlgN family protein
C5Y82_16435	COG1040	competence protein
C5Y82_16445	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C5Y82_16450	COG1307	EDD domain protein, DegV family
C5Y82_16455	COG2197	response regulator
C5Y82_16460	COG4585	Histidine kinase
C5Y82_16465	COG1739	Uncharacterized protein family UPF0029
C5Y82_16470	COG1316	TRANSCRIPTIONal
C5Y82_16475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C5Y82_16480	COG0438	transferase activity, transferring glycosyl groups
C5Y82_16485	COG1215	transferase activity, transferring glycosyl groups
C5Y82_16490	COG3206	protein involved in exopolysaccharide biosynthesis
C5Y82_16495	COG3307	-O-antigen
C5Y82_16500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5Y82_16505	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C5Y82_16510	COG0297	glycogen (starch) synthase activity
C5Y82_16510	COG0438	transferase activity, transferring glycosyl groups
C5Y82_16515	COG2244	polysaccharide biosynthetic process
C5Y82_16530	COG0860	N-Acetylmuramoyl-L-alanine amidase
C5Y82_16530	COG2247	cell wall binding repeat
C5Y82_16535	COG2385	sporulation resulting in formation of a cellular spore
C5Y82_16535	COG2247	cell wall binding repeat
C5Y82_16545	COG1316	TRANSCRIPTIONal
C5Y82_16550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C5Y82_16555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C5Y82_16565	COG1134	teichoic acid transport
C5Y82_16570	COG1682	transport, permease protein
C5Y82_16575	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C5Y82_16610	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C5Y82_16615	COG0438	transferase activity, transferring glycosyl groups
C5Y82_16620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C5Y82_16625	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C5Y82_16630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C5Y82_16635	COG4193	domain, Protein
C5Y82_16640	COG0463	Glycosyl transferase, family 2
C5Y82_16640	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C5Y82_16645	COG1482	cell wall glycoprotein biosynthetic process
C5Y82_16655	COG1175	transmembrane transport
C5Y82_16660	COG1653	transport
C5Y82_16665	COG2197	response regulator
C5Y82_16670	COG2972	Histidine kinase
C5Y82_16680	COG0454	-acetyltransferase
C5Y82_16685	COG0800	Aldolase
C5Y82_16690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5Y82_16695	COG1609	Transcriptional regulator
C5Y82_16700	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
C5Y82_16705	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_16710	COG0697	spore germination
C5Y82_16715	COG0814	amino acid
C5Y82_16725	COG1215	transferase activity, transferring glycosyl groups
C5Y82_16730	COG2814	Major facilitator Superfamily
C5Y82_16735	COG1316	TRANSCRIPTIONal
C5Y82_16740	COG0561	phosphatase activity
C5Y82_16745	COG0791	NLP P60 protein
C5Y82_16750	COG2843	Capsule synthesis protein
C5Y82_16760	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C5Y82_16765	COG0697	spore germination
C5Y82_16780	COG1609	Transcriptional regulator
C5Y82_16785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5Y82_16790	COG1869	D-ribose catabolic process
C5Y82_16795	COG1129	ABC transporter
C5Y82_16800	COG1172	Belongs to the binding-protein-dependent transport system permease family
C5Y82_16805	COG1879	ABC-type sugar transport system periplasmic component
C5Y82_16810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C5Y82_16815	COG0583	DNA-binding transcription factor activity
C5Y82_16820	COG0028	Belongs to the TPP enzyme family
C5Y82_16825	COG3527	Alpha-acetolactate decarboxylase
C5Y82_16830	COG1522	sequence-specific DNA binding
C5Y82_16835	COG2059	Chromate
C5Y82_16840	COG2059	Chromate
C5Y82_16845	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C5Y82_16850	COG4715	Zinc finger, swim domain protein
C5Y82_16855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C5Y82_16860	COG2202	Pas domain
C5Y82_16860	COG1366	Belongs to the anti-sigma-factor antagonist family
C5Y82_16865	COG0561	phosphatase activity
C5Y82_16880	COG1970	mechanosensitive ion channel activity
C5Y82_16885	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C5Y82_16890	COG0457	Tetratricopeptide repeat
C5Y82_16895	COG4786	Flagellar basal body rod
C5Y82_16900	COG4786	Flagellar basal body rod
C5Y82_16905	COG1077	Cell shape determining protein MreB Mrl
C5Y82_16910	COG1609	Transcriptional regulator
C5Y82_16915	COG1846	Transcriptional regulator
C5Y82_16920	COG2814	Major facilitator Superfamily
C5Y82_16925	COG0671	phosphoesterase, PA-phosphatase related
C5Y82_16930	COG0477	Major facilitator Superfamily
C5Y82_16935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5Y82_16940	COG0765	amino acid transport
C5Y82_16945	COG1126	abc transporter atp-binding protein
C5Y82_16955	COG0004	ammonium transporteR
C5Y82_16960	COG0347	Belongs to the P(II) protein family
C5Y82_16965	COG0739	heme binding
C5Y82_16970	COG1247	-acetyltransferase
C5Y82_17015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C5Y82_17020	COG0523	cobalamin synthesis protein
C5Y82_17025	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C5Y82_17035	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C5Y82_17040	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C5Y82_17050	COG0243	molybdopterin cofactor binding
C5Y82_17055	COG2304	oxidoreductase activity
C5Y82_17060	COG2304	oxidoreductase activity
C5Y82_17065	COG2385	sporulation resulting in formation of a cellular spore
C5Y82_17070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C5Y82_17080	COG4836	Membrane
C5Y82_17090	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C5Y82_17095	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C5Y82_17100	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C5Y82_17105	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C5Y82_17110	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C5Y82_17115	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C5Y82_17120	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C5Y82_17125	COG0356	it plays a direct role in the translocation of protons across the membrane
C5Y82_17135	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C5Y82_17140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C5Y82_17145	COG4475	Protein of unknown function (DUF436)
C5Y82_17150	COG0698	ribose 5-phosphate isomerase
C5Y82_17155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C5Y82_17160	COG1971	Probably functions as a manganese efflux pump
C5Y82_17165	COG0009	L-threonylcarbamoyladenylate synthase
C5Y82_17170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C5Y82_17185	COG2890	protein-(glutamine-N5) methyltransferase activity
C5Y82_17190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C5Y82_17195	COG0789	Transcriptional regulator
C5Y82_17200	COG0679	Auxin Efflux Carrier
C5Y82_17205	COG0281	malic enzyme
C5Y82_17210	COG1435	thymidine kinase activity
C5Y82_17215	COG0254	rRNA binding
C5Y82_17220	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C5Y82_17225	COG1494	fructose-1,6-bisphosphatase
C5Y82_17230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C5Y82_17235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C5Y82_17240	COG0191	fructose-bisphosphate aldolase activity
C5Y82_17245	COG2204	response regulator
C5Y82_17250	COG4821	SIS domain
C5Y82_17255	COG0504	CTP synthase activity
C5Y82_17260	COG3343	RNA polymerase activity
C5Y82_17270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C5Y82_17300	COG1960	acyl-CoA dehydrogenase activity
C5Y82_17305	COG1960	acyl-CoA dehydrogenase activity
C5Y82_17310	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5Y82_17315	COG0183	Belongs to the thiolase family
C5Y82_17320	COG0247	lactate metabolic process
C5Y82_17320	COG2181	nitrate reductase activity
C5Y82_17325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5Y82_17330	COG4294	response to UV
C5Y82_17340	COG1619	proteins homologs of microcin C7 resistance protein MccF
C5Y82_17345	COG1132	(ABC) transporter
C5Y82_17350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5Y82_17355	COG1619	proteins homologs of microcin C7 resistance protein MccF
C5Y82_17365	COG0018	arginyl-trna synthetase
C5Y82_17370	COG4506	Protein conserved in bacteria
C5Y82_17380	COG0010	Belongs to the arginase family
C5Y82_17385	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C5Y82_17390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5Y82_17400	COG1994	Peptidase M50
C5Y82_17405	COG1942	4-Oxalocrotonate Tautomerase
C5Y82_17415	COG3465	dGTPase activity
C5Y82_17420	COG1078	dGTPase activity
C5Y82_17425	COG4844	belongs to the
C5Y82_17470	COG5444	nuclease activity
C5Y82_17505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C5Y82_17515	COG0280	phosphate acetyltransferase
C5Y82_17525	COG2814	Major facilitator Superfamily
C5Y82_17530	COG1522	sequence-specific DNA binding
C5Y82_17535	COG2814	Major facilitator Superfamily
C5Y82_17540	COG0077	Prephenate dehydratase
C5Y82_17545	COG1917	Cupin 2, conserved barrel domain protein
C5Y82_17550	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_17555	COG0151	Belongs to the GarS family
C5Y82_17560	COG0436	Aminotransferase
C5Y82_17565	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_17570	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C5Y82_17575	COG1091	dTDP-4-dehydrorhamnose reductase activity
C5Y82_17580	COG1088	dTDP-glucose 4,6-dehydratase activity
C5Y82_17585	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C5Y82_17590	COG3980	spore coat polysaccharide biosynthesis protein
C5Y82_17595	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C5Y82_17600	COG2089	acid synthase
C5Y82_17605	COG0456	acetyltransferase
C5Y82_17610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5Y82_17615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C5Y82_17620	COG0463	Glycosyl transferase, family 2
C5Y82_17640	COG2363	Small membrane protein
C5Y82_17645	COG2233	PERMEase
C5Y82_17655	COG1012	belongs to the aldehyde dehydrogenase family
C5Y82_17660	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C5Y82_17665	COG1216	Glycosyl transferase, family 2
C5Y82_17675	COG0351	phosphomethylpyrimidine kinase
C5Y82_17690	COG1621	beta-fructofuranosidase activity
C5Y82_17695	COG1263	PTS System
C5Y82_17695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5Y82_17700	COG3711	transcriptional antiterminator
C5Y82_17710	COG1404	Belongs to the peptidase S8 family
C5Y82_17720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5Y82_17725	COG0778	Nitroreductase
C5Y82_17730	COG0772	Belongs to the SEDS family
C5Y82_17745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C5Y82_17750	COG1845	cytochrome c oxidase, subunit III
C5Y82_17755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C5Y82_17760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C5Y82_17770	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C5Y82_17775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C5Y82_17780	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C5Y82_17795	COG2246	polysaccharide biosynthetic process
C5Y82_17820	COG0457	Tetratricopeptide repeat
C5Y82_17835	COG3162	membrane
C5Y82_17840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5Y82_17855	COG0352	thiamine-phosphate diphosphorylase activity
C5Y82_17860	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C5Y82_17865	COG0583	DNA-binding transcription factor activity
C5Y82_17875	COG1346	cytolysis
C5Y82_17880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C5Y82_17885	COG0346	lactoylglutathione lyase activity
C5Y82_17895	COG0765	amino acid transport
C5Y82_17900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5Y82_17905	COG0457	Tetratricopeptide repeat
C5Y82_17910	COG2357	RelA SpoT domain protein
C5Y82_17915	COG1172	Belongs to the binding-protein-dependent transport system permease family
C5Y82_17920	COG1129	ABC transporter
C5Y82_17930	COG3420	alginic acid biosynthetic process
C5Y82_17935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5Y82_17950	COG1486	melibiose metabolic process
C5Y82_17955	COG1447	Phosphotransferase system cellobiose-specific component IIA
C5Y82_17960	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5Y82_17965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5Y82_17970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5Y82_17970	COG3711	transcriptional antiterminator
C5Y82_17985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C5Y82_18000	COG1595	DNA-templated transcription, initiation
C5Y82_18005	COG3866	Pectate lyase
C5Y82_18010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C5Y82_18015	COG4988	ABC transporter
C5Y82_18020	COG1294	oxidase, subunit
C5Y82_18025	COG1271	oxidase subunit
C5Y82_18045	COG4509	Sortase family
C5Y82_18065	COG5386	Cell surface protein
C5Y82_18070	COG5386	Cell surface protein
C5Y82_18075	COG1733	regulation of RNA biosynthetic process
C5Y82_18080	COG2514	catechol 2,3-dioxygenase activity
C5Y82_18085	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C5Y82_18085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C5Y82_18090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5Y82_18090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5Y82_18100	COG0726	polysaccharide deacetylase
C5Y82_18105	COG1447	Phosphotransferase system cellobiose-specific component IIA
C5Y82_18110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5Y82_18115	COG2723	6-phospho-beta-galactosidase activity
C5Y82_18125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5Y82_18130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5Y82_18130	COG3711	transcriptional antiterminator
C5Y82_18155	COG1757	Na H antiporter
C5Y82_18160	COG1027	Aspartate ammonia-lyase
C5Y82_18165	COG0252	asparaginase activity
C5Y82_18170	COG1396	sequence-specific DNA binding
C5Y82_18195	COG4842	Belongs to the WXG100 family
C5Y82_18200	COG2195	Cleaves the N-terminal amino acid of tripeptides
C5Y82_18215	COG1737	Transcriptional regulator
C5Y82_18220	COG2084	Dehydrogenase
C5Y82_18230	COG2610	gluconate transmembrane transporter activity
C5Y82_18235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C5Y82_18245	COG1136	(ABC) transporter
C5Y82_18250	COG2723	6-phospho-beta-galactosidase activity
C5Y82_18255	COG2190	(PTS) system
C5Y82_18255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5Y82_18255	COG1263	PTS System
C5Y82_18260	COG3711	transcriptional antiterminator
C5Y82_18265	COG3878	Protein conserved in bacteria
C5Y82_18275	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C5Y82_18280	COG1122	ATPase activity
C5Y82_18285	COG4721	ABC-type cobalt transport system, permease component
C5Y82_18290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C5Y82_18315	COG4412	M6 family metalloprotease domain protein
C5Y82_18315	COG3291	Pkd domain containing protein
C5Y82_18320	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C5Y82_18325	COG0778	Nitroreductase
C5Y82_18330	COG1846	Transcriptional regulator
C5Y82_18335	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C5Y82_18340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C5Y82_18345	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C5Y82_18350	COG2390	Transcriptional regulator
C5Y82_18365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C5Y82_18365	COG2755	lipolytic protein G-D-S-L family
C5Y82_18370	COG0477	Major facilitator Superfamily
C5Y82_18390	COG0561	phosphatase activity
C5Y82_18395	COG0789	Transcriptional regulator
C5Y82_18400	COG0673	inositol 2-dehydrogenase activity
C5Y82_18405	COG0840	transmembrane signaling receptor activity
C5Y82_18410	COG1113	amino acid transport
C5Y82_18415	COG4335	DNA alkylation repair
C5Y82_18425	COG1070	Carbohydrate kinase
C5Y82_18430	COG1737	Transcriptional regulator
C5Y82_18460	COG0583	DNA-binding transcription factor activity
C5Y82_18465	COG1609	Transcriptional regulator
C5Y82_18470	COG2182	Extracellular solute-binding protein
C5Y82_18475	COG1175	transmembrane transport
C5Y82_18480	COG3833	ABC-type maltose transport systems, permease component
C5Y82_18490	COG1874	Beta-galactosidase
C5Y82_18495	COG2851	Citrate transporter
C5Y82_18505	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C5Y82_18510	COG1131	(ABC) transporter
C5Y82_18515	COG2824	Alkylphosphonate utilization operon protein PhnA
C5Y82_18520	COG1929	Belongs to the glycerate kinase type-1 family
C5Y82_18525	COG2610	gluconate transmembrane transporter activity
C5Y82_18530	COG3835	regulator
C5Y82_18535	COG1309	transcriptional regulator
C5Y82_18540	COG2814	Major facilitator Superfamily
C5Y82_18550	COG1136	(ABC) transporter
C5Y82_18560	COG0457	Tetratricopeptide repeat
C5Y82_18565	COG3711	transcriptional antiterminator
C5Y82_18570	COG2723	6-phospho-beta-galactosidase activity
C5Y82_18575	COG2190	(PTS) system
C5Y82_18575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5Y82_18575	COG1263	PTS System
C5Y82_18615	COG1113	amino acid transport
C5Y82_18625	COG2814	Major facilitator Superfamily
C5Y82_18630	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C5Y82_18635	COG2814	Major facilitator Superfamily
C5Y82_18650	COG2723	6-phospho-beta-galactosidase activity
C5Y82_18655	COG2188	Transcriptional regulator
C5Y82_18670	COG0384	phenazine biosynthesis protein PhzF
C5Y82_18675	COG0583	DNA-binding transcription factor activity
C5Y82_18710	COG0210	DNA helicase
C5Y82_18725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C5Y82_18735	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C5Y82_18745	COG4720	Psort location CytoplasmicMembrane, score
C5Y82_18765	COG0456	acetyltransferase
C5Y82_18770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5Y82_18775	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C5Y82_18780	COG4853	Protein conserved in bacteria
C5Y82_18785	COG4863	YycH protein
C5Y82_18790	COG5002	protein histidine kinase activity
C5Y82_18795	COG0745	RESPONSE REGULATOR receiver
C5Y82_18820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5Y82_18830	COG2311	Membrane
C5Y82_18835	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C5Y82_18840	COG1309	transcriptional regulator
C5Y82_18845	COG2124	cytochrome p450
C5Y82_18850	COG0346	lactoylglutathione lyase activity
C5Y82_18855	COG0305	Participates in initiation and elongation during chromosome replication
C5Y82_18875	COG2819	hydrolase of the alpha beta superfamily
C5Y82_18880	COG1028	Short-chain dehydrogenase reductase Sdr
C5Y82_18885	COG1169	isochorismate synthase
C5Y82_18890	COG1021	2,3-dihydroxybenzoate-AMP ligase
C5Y82_18895	COG1535	isochorismatase
C5Y82_18895	COG3433	isochorismatase activity
C5Y82_18900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5Y82_18905	COG3251	PFAM MbtH domain protein
C5Y82_18910	COG2207	Transcriptional regulator
C5Y82_18910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5Y82_18915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5Y82_18920	COG2819	hydrolase of the alpha beta superfamily
C5Y82_18925	COG3093	addiction module antidote protein HigA
C5Y82_18930	COG2807	transmembrane transport
C5Y82_18940	COG0359	binds to the 23S rRNA
C5Y82_18945	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C5Y82_18950	COG4241	membrane
C5Y82_18955	COG1227	inorganic diphosphatase activity
C5Y82_18965	COG1595	DNA-templated transcription, initiation
C5Y82_18975	COG0753	catalase activity
C5Y82_18980	COG0655	NAD(P)H dehydrogenase (quinone) activity
C5Y82_18985	COG0400	carboxylic ester hydrolase activity
C5Y82_18990	COG0346	lactoylglutathione lyase activity
C5Y82_18995	COG1174	glycine betaine transport
C5Y82_19000	COG0517	IMP dehydrogenase activity
C5Y82_19000	COG1125	glycine betaine transport
C5Y82_19005	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C5Y82_19010	COG0629	single-stranded DNA binding
C5Y82_19015	COG0360	Binds together with S18 to 16S ribosomal RNA
C5Y82_19020	COG0012	GTP binding
C5Y82_19025	COG4481	Protein conserved in bacteria
C5Y82_19040	COG3949	Membrane
C5Y82_19050	COG1475	DNA binding
C5Y82_19055	COG1192	Involved in chromosome partitioning
C5Y82_19070	COG1475	DNA binding
C5Y82_19075	COG0357	Ribosomal RNA small subunit methyltransferase G
C5Y82_19080	COG0445	tRNA wobble uridine modification
C5Y82_19085	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C5Y82_19090	COG1847	R3H domain protein
C5Y82_19095	COG0706	membrane insertase activity
C5Y82_19100	COG0594	ribonuclease P activity
C5Y82_19105	COG0230	Belongs to the bacterial ribosomal protein bL34 family