locus-tag	class	description
LG951_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LG951_00010	COG0592	DNA-directed DNA polymerase activity
LG951_00015	COG2501	S4 domain
LG951_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LG951_00030	COG0187	DNA topoisomerase II activity
LG951_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LG951_00070	COG0516	GMP reductase activity
LG951_00070	COG0517	IMP dehydrogenase activity
LG951_00075	COG1686	Belongs to the peptidase S11 family
LG951_00080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG951_00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LG951_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LG951_00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LG951_00110	COG1428	Deoxynucleoside kinase
LG951_00115	COG1428	Deoxynucleoside kinase
LG951_00120	COG3858	chitin binding
LG951_00120	COG1388	LysM domain
LG951_00125	COG1335	isochorismatase
LG951_00130	COG0590	tRNA wobble adenosine to inosine editing
LG951_00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LG951_00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LG951_00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LG951_00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
LG951_00200	COG3853	Toxic anion resistance protein (TelA)
LG951_00205	COG1982	Orn Lys Arg decarboxylase major
LG951_00210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LG951_00215	COG3870	Protein conserved in bacteria
LG951_00220	COG1728	Protein conserved in bacteria
LG951_00225	COG0470	DNA polymerase III
LG951_00230	COG1774	PSP1 C-terminal conserved region
LG951_00235	COG4467	Involved in initiation control of chromosome replication
LG951_00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LG951_00245	COG2827	Endonuclease containing a URI domain
LG951_00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LG951_00255	COG2002	toxin-antitoxin pair type II binding
LG951_00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG951_00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG951_00265	COG0084	hydrolase, TatD family'
LG951_00270	COG3583	domain protein
LG951_00270	COG3584	3D domain protein
LG951_00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LG951_00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LG951_00290	COG4466	Protein conserved in bacteria
LG951_00300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LG951_00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LG951_00310	COG0251	oxidation-reduction process
LG951_00315	COG2088	sporulation resulting in formation of a cellular spore
LG951_00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LG951_00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LG951_00335	COG0193	aminoacyl-tRNA hydrolase activity
LG951_00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LG951_00350	COG2002	toxin-antitoxin pair type II binding
LG951_00355	COG2244	polysaccharide biosynthetic process
LG951_00360	COG3956	TIGRFAM MazG family protein
LG951_00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LG951_00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LG951_00385	COG1098	S1 RNA binding domain
LG951_00400	COG2208	phosphoserine phosphatase activity
LG951_00405	COG2304	oxidoreductase activity
LG951_00410	COG0515	serine threonine protein kinase
LG951_00415	COG0037	tRNA processing
LG951_00420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LG951_00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LG951_00430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LG951_00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LG951_00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LG951_00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LG951_00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LG951_00455	COG0512	Glutamine amidotransferase of anthranilate synthase
LG951_00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LG951_00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LG951_00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LG951_00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LG951_00480	COG1396	sequence-specific DNA binding
LG951_00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LG951_00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LG951_00570	COG4463	regulation of RNA biosynthetic process
LG951_00575	COG3880	PFAM UvrB UvrC protein
LG951_00580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
LG951_00585	COG0542	response to heat
LG951_00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LG951_00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LG951_00600	COG4956	integral membrane protein (PIN domain superfamily)
LG951_00605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LG951_00610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LG951_00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LG951_00620	COG1045	serine acetyltransferase
LG951_00625	COG0215	cysteine-tRNA ligase activity
LG951_00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LG951_00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LG951_00640	COG3688	RNA-binding protein containing a PIN domain
LG951_00645	COG1595	DNA-templated transcription, initiation
LG951_00650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LG951_00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LG951_00660	COG0250	Participates in transcription elongation, termination and antitermination
LG951_00670	COG0081	regulation of translation
LG951_00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LG951_00680	COG0222	ribosome binding
LG951_00685	COG2813	Specifically methylates the guanine in position
LG951_00690	COG0085	RNA polymerase activity
LG951_00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LG951_00700	COG1358	cellular component organization or biogenesis
LG951_00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LG951_00710	COG0049	tRNA binding
LG951_00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LG951_00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LG951_00725	COG0596	Alpha beta hydrolase
LG951_00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LG951_00740	COG0088	Forms part of the polypeptide exit tunnel
LG951_00745	COG0089	rRNA binding
LG951_00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LG951_00755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LG951_00760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LG951_00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LG951_00770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LG951_00775	COG0255	Belongs to the universal ribosomal protein uL29 family
LG951_00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LG951_00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LG951_00790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LG951_00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LG951_00800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LG951_00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LG951_00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LG951_00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LG951_00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LG951_00825	COG1841	ribosomal large subunit assembly
LG951_00830	COG0200	Binds to the 23S rRNA
LG951_00835	COG0201	protein transport
LG951_00840	COG0563	adenylate kinase activity
LG951_00845	COG0024	Methionine aminopeptidase
LG951_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LG951_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LG951_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LG951_00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LG951_00875	COG0202	RNA polymerase activity
LG951_00880	COG0203	ribosomal protein L17
LG951_00885	COG1122	ATPase activity
LG951_00890	COG1122	ATPase activity
LG951_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LG951_00900	COG0101	tRNA pseudouridine synthase activity
LG951_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LG951_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LG951_00915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LG951_00945	COG0860	N-Acetylmuramoyl-L-alanine amidase
LG951_00950	COG0489	protein tyrosine kinase activity
LG951_00960	COG2194	sulfuric ester hydrolase activity
LG951_00965	COG0726	polysaccharide deacetylase
LG951_01000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LG951_01005	COG0385	Bile acid
LG951_01010	COG3876	Protein conserved in bacteria
LG951_01015	COG1472	Belongs to the glycosyl hydrolase 3 family
LG951_01020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LG951_01025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG951_01025	COG1263	PTS System
LG951_01030	COG1737	Transcriptional regulator
LG951_01035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LG951_01070	COG1595	DNA-templated transcription, initiation
LG951_01075	COG5662	AntiSigma factor
LG951_01080	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LG951_01085	COG4856	YbbR-like protein
LG951_01090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LG951_01095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LG951_01115	COG1131	(ABC) transporter
LG951_01130	COG1131	(ABC) transporter
LG951_01140	COG1413	lyase activity
LG951_01145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG951_01150	COG2311	Membrane
LG951_01170	COG1476	TRANSCRIPTIONal
LG951_01180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LG951_01185	COG1309	transcriptional regulator
LG951_01200	COG1113	amino acid transport
LG951_01205	COG0584	glycerophosphoryl diester phosphodiesterase
LG951_01210	COG2271	Major facilitator Superfamily
LG951_01220	COG1331	Highly conserved protein containing a thioredoxin domain
LG951_01240	COG1937	Protein conserved in bacteria
LG951_01245	COG2210	Belongs to the sulfur carrier protein TusA family
LG951_01250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LG951_01255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LG951_01255	COG0425	Belongs to the sulfur carrier protein TusA family
LG951_01260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG951_01260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LG951_01265	COG0425	Belongs to the sulfur carrier protein TusA family
LG951_01270	COG0730	response to heat
LG951_01280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LG951_01285	COG2814	Major facilitator Superfamily
LG951_01295	COG1846	Transcriptional regulator
LG951_01315	COG0656	L-ascorbic acid biosynthetic process
LG951_01320	COG0371	Dehydrogenase
LG951_01325	COG1054	Belongs to the UPF0176 family
LG951_01330	COG0531	amino acid
LG951_01340	COG3711	transcriptional antiterminator
LG951_01345	COG2190	(PTS) system
LG951_01345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG951_01345	COG1263	PTS System
LG951_01350	COG2723	6-phospho-beta-galactosidase activity
LG951_01370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG951_01370	COG3711	transcriptional antiterminator
LG951_01375	COG1940	carbohydrate kinase activity
LG951_01380	COG0383	alpha-mannosidase activity
LG951_01385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG951_01390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG951_01400	COG1404	Belongs to the peptidase S8 family
LG951_01415	COG0833	amino acid
LG951_01420	COG2040	homocysteine
LG951_01425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LG951_01430	COG1695	Transcriptional regulator
LG951_01445	COG2814	Major facilitator Superfamily
LG951_01450	COG0456	acetyltransferase
LG951_01465	COG1404	Belongs to the peptidase S8 family
LG951_01475	COG1309	transcriptional regulator
LG951_01480	COG1917	Cupin 2, conserved barrel domain protein
LG951_01485	COG1063	alcohol dehydrogenase
LG951_01490	COG1846	Transcriptional regulator
LG951_01495	COG0318	PFAM AMP-dependent synthetase and ligase
LG951_01500	COG0531	amino acid
LG951_01510	COG0596	Alpha beta hydrolase
LG951_01515	COG1115	amino acid carrier protein
LG951_01520	COG2066	Belongs to the glutaminase family
LG951_01525	COG4191	Histidine kinase
LG951_01530	COG0784	Response regulator, receiver
LG951_01535	COG1405	negative regulation of cell septum assembly
LG951_01535	COG3012	SEC-C Motif Domain Protein
LG951_01545	COG0667	Aldo Keto reductase
LG951_01550	COG3290	protein histidine kinase activity
LG951_01555	COG3279	Response regulator of the LytR AlgR family
LG951_01560	COG4555	ABC transporter
LG951_01565	COG1668	transmembrane transport
LG951_01580	COG3773	Cell wall hydrolase
LG951_01585	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_01595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG951_01600	COG2310	stress, protein
LG951_01605	COG2310	stress, protein
LG951_01610	COG2310	stress, protein
LG951_01615	COG0861	Integral membrane protein TerC family
LG951_01645	COG3853	Toxic anion resistance protein (TelA)
LG951_01650	COG0517	IMP dehydrogenase activity
LG951_01650	COG4175	Glycine betaine
LG951_01655	COG4176	ABC-type proline glycine betaine transport system permease component
LG951_01660	COG2113	Glycine betaine
LG951_01675	COG1473	amidohydrolase
LG951_01680	COG1288	antiporter activity
LG951_01685	COG0039	L-malate dehydrogenase activity
LG951_01690	COG1620	l-lactate permease
LG951_01695	COG1609	Transcriptional regulator
LG951_01700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LG951_01705	COG0561	phosphatase activity
LG951_01710	COG0673	inositol 2-dehydrogenase activity
LG951_01715	COG0738	Major facilitator superfamily
LG951_01720	COG1280	lysine exporter protein (LysE YggA)
LG951_01730	COG3403	YqcI/YcgG family
LG951_01735	COG1113	amino acid transport
LG951_01740	COG3665	Urea carboxylase-associated protein
LG951_01745	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LG951_01755	COG1012	belongs to the aldehyde dehydrogenase family
LG951_01760	COG0710	3-dehydroquinate dehydratase activity
LG951_01765	COG0028	Belongs to the TPP enzyme family
LG951_01775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LG951_01780	COG2271	Major facilitator Superfamily
LG951_01795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LG951_01800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LG951_01810	COG0477	Major facilitator Superfamily
LG951_01815	COG2226	methyltransferase
LG951_01820	COG0583	DNA-binding transcription factor activity
LG951_01825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LG951_01830	COG3458	cephalosporin-C deacetylase activity
LG951_01840	COG3541	Predicted nucleotidyltransferase
LG951_01845	COG0506	proline dehydrogenase activity
LG951_01850	COG1012	belongs to the aldehyde dehydrogenase family
LG951_01855	COG2508	Transcriptional regulator
LG951_01860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LG951_01865	COG0765	amino acid transport
LG951_01870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG951_01880	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LG951_01885	COG1522	sequence-specific DNA binding
LG951_01890	COG2746	aminoglycoside 3-N-acetyltransferase activity
LG951_01900	COG0840	transmembrane signaling receptor activity
LG951_01900	COG3290	protein histidine kinase activity
LG951_01905	COG3209	COG3209 Rhs family protein
LG951_01925	COG3842	ATPase activity
LG951_01930	COG1176	ABC-type spermidine putrescine transport system, permease component I
LG951_01940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG951_01945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG951_01950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG951_01965	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LG951_01970	COG0697	spore germination
LG951_01975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG951_01985	COG2364	Membrane
LG951_01990	COG0737	Belongs to the 5'-nucleotidase family
LG951_01995	COG3764	Sortase (surface protein transpeptidase)
LG951_02000	COG2002	toxin-antitoxin pair type II binding
LG951_02005	COG1126	abc transporter atp-binding protein
LG951_02010	COG0765	amino acid transport
LG951_02015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG951_02020	COG0833	amino acid
LG951_02025	COG3104	oligopeptide transport
LG951_02030	COG5434	Belongs to the glycosyl hydrolase 28 family
LG951_02035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG951_02040	COG0456	acetyltransferase
LG951_02045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG951_02050	COG0765	amino acid transport
LG951_02055	COG1126	abc transporter atp-binding protein
LG951_02060	COG1473	amidohydrolase
LG951_02065	COG2079	MmgE PrpD family protein
LG951_02070	COG1366	Belongs to the anti-sigma-factor antagonist family
LG951_02075	COG0527	aspartate kinase activity
LG951_02080	COG2814	Major facilitator Superfamily
LG951_02085	COG1309	transcriptional regulator
LG951_02095	COG0640	Transcriptional regulator
LG951_02100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG951_02105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LG951_02110	COG0531	amino acid
LG951_02115	COG1012	belongs to the aldehyde dehydrogenase family
LG951_02120	COG2249	NAD(P)H dehydrogenase (quinone) activity
LG951_02125	COG4549	nuclear export factor GLE1
LG951_02130	COG2372	response to copper ion
LG951_02130	COG1276	copper resistance
LG951_02135	COG2213	PTS system mannitol-specific
LG951_02140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG951_02145	COG0246	Mannitol dehydrogenase
LG951_02150	COG0840	transmembrane signaling receptor activity
LG951_02170	COG0346	lactoylglutathione lyase activity
LG951_02180	COG0561	phosphatase activity
LG951_02185	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LG951_02190	COG1914	H( )-stimulated, divalent metal cation uptake system
LG951_02195	COG4336	lyase activity
LG951_02200	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LG951_02205	COG1984	allophanate hydrolase subunit 2
LG951_02210	COG1414	Transcriptional regulator
LG951_02215	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LG951_02220	COG2755	lipolytic protein G-D-S-L family
LG951_02230	COG3711	transcriptional antiterminator
LG951_02235	COG2226	methyltransferase
LG951_02240	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_02245	COG3871	stress protein (general stress protein 26)
LG951_02265	COG2814	Major facilitator Superfamily
LG951_02270	COG0551	DNA topoisomerase type I activity
LG951_02270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LG951_02275	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LG951_02280	COG3706	GGDEF domain
LG951_02285	COG5298	Protein conserved in bacteria
LG951_02290	COG1215	transferase activity, transferring glycosyl groups
LG951_02300	COG0531	amino acid
LG951_02305	COG0028	Belongs to the TPP enzyme family
LG951_02310	COG5444	nuclease activity
LG951_02335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LG951_02340	COG1914	H( )-stimulated, divalent metal cation uptake system
LG951_02345	COG2261	transglycosylase associated protein
LG951_02350	COG2217	Heavy metal translocating P-type atpase
LG951_02355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LG951_02360	COG3290	protein histidine kinase activity
LG951_02365	COG4565	transcriptional regulatory protein
LG951_02370	COG1301	dicarboxylic acid transport
LG951_02375	COG0628	permease
LG951_02380	COG1301	dicarboxylic acid transport
LG951_02385	COG1131	(ABC) transporter
LG951_02390	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LG951_02405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG951_02410	COG1181	Belongs to the D-alanine--D-alanine ligase family
LG951_02415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LG951_02430	COG0513	Belongs to the DEAD box helicase family
LG951_02435	COG3402	PFAM membrane-flanked domain
LG951_02440	COG3428	Bacterial PH domain
LG951_02445	COG0705	Rhomboid family
LG951_02450	COG0736	holo-[acyl-carrier-protein] synthase activity
LG951_02455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LG951_02460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LG951_02465	COG0864	Transcriptional regulator
LG951_02470	COG2337	Toxic component of a toxin-antitoxin (TA) module
LG951_02475	COG1366	Belongs to the anti-sigma-factor antagonist family
LG951_02480	COG1366	Belongs to the anti-sigma-factor antagonist family
LG951_02485	COG2172	sigma factor antagonist activity
LG951_02490	COG2208	phosphoserine phosphatase activity
LG951_02495	COG1366	Belongs to the anti-sigma-factor antagonist family
LG951_02500	COG2172	sigma factor antagonist activity
LG951_02505	COG1191	sigma factor activity
LG951_02510	COG2208	phosphoserine phosphatase activity
LG951_02515	COG2183	response to ionizing radiation
LG951_02525	COG3091	SprT-like family
LG951_02530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LG951_02535	COG0022	dehydrogenase e1 component
LG951_02540	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG951_02545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LG951_02550	COG3284	Transcriptional regulator
LG951_02595	COG0604	alcohol dehydrogenase
LG951_02615	COG1278	Cold shock
LG951_02620	COG1329	Transcriptional regulator
LG951_02625	COG1064	alcohol dehydrogenase
LG951_02630	COG0789	Transcriptional regulator
LG951_02645	COG0477	Major facilitator Superfamily
LG951_02650	COG0657	acetylesterase activity
LG951_02660	COG4221	oxidoreductase activity
LG951_02675	COG0252	asparaginase activity
LG951_02695	COG2814	Major facilitator Superfamily
LG951_02700	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LG951_02705	COG2409	Drug exporters of the RND superfamily
LG951_02710	COG4585	Histidine kinase
LG951_02745	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LG951_02750	COG1846	Transcriptional regulator
LG951_02755	COG0778	Nitroreductase
LG951_02770	COG1396	sequence-specific DNA binding
LG951_02780	COG0456	acetyltransferase
LG951_02785	COG0583	DNA-binding transcription factor activity
LG951_02790	COG0667	Aldo Keto reductase
LG951_02800	COG4122	O-methyltransferase activity
LG951_02810	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LG951_02815	COG0697	spore germination
LG951_02825	COG1301	dicarboxylic acid transport
LG951_02865	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LG951_02870	COG0802	atpase or kinase
LG951_02875	COG1214	PFAM Peptidase M22, glycoprotease
LG951_02880	COG0456	acetyltransferase
LG951_02885	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LG951_02890	COG0488	(ABC) transporter
LG951_02895	COG0315	cyclic pyranopterin monophosphate synthase activity
LG951_02900	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LG951_02905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LG951_02910	COG0805	protein transport
LG951_02915	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LG951_02925	COG1266	CAAX protease self-immunity
LG951_02930	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LG951_02935	COG0459	protein refolding
LG951_02995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LG951_03000	COG0823	Involved in the tonB-independent uptake of proteins
LG951_03010	COG2132	Multicopper oxidase
LG951_03015	COG1113	amino acid transport
LG951_03020	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LG951_03025	COG0714	Associated with various cellular activities
LG951_03030	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LG951_03035	COG1305	Transglutaminase-like
LG951_03040	COG0519	Catalyzes the synthesis of GMP from XMP
LG951_03040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LG951_03045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LG951_03050	COG1917	Cupin 2, conserved barrel domain protein
LG951_03050	COG2207	Transcriptional regulator
LG951_03055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LG951_03060	COG2207	Transcriptional regulator
LG951_03105	COG1595	DNA-templated transcription, initiation
LG951_03115	COG2814	Major facilitator Superfamily
LG951_03120	COG0583	DNA-binding transcription factor activity
LG951_03130	COG2252	PERMEase
LG951_03135	COG3064	Membrane
LG951_03140	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
LG951_03150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LG951_03155	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LG951_03160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LG951_03165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LG951_03170	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LG951_03175	COG0047	phosphoribosylformylglycinamidine synthase activity
LG951_03180	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LG951_03185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LG951_03190	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LG951_03195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LG951_03200	COG0138	bifunctional purine biosynthesis protein purh
LG951_03205	COG0151	Belongs to the GarS family
LG951_03220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LG951_03225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LG951_03230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LG951_03235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LG951_03245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LG951_03250	COG4496	protein, YerC YecD
LG951_03265	COG0069	glutamate synthase activity
LG951_03280	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LG951_03285	COG0210	DNA helicase
LG951_03290	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LG951_03295	COG4851	CamS sex pheromone cAM373 precursor
LG951_03310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LG951_03325	COG1250	3-hydroxyacyl-CoA dehydrogenase
LG951_03340	COG1960	acyl-CoA dehydrogenase activity
LG951_03370	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LG951_03375	COG1785	Belongs to the alkaline phosphatase family
LG951_03380	COG1285	pathogenesis
LG951_03385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LG951_03390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LG951_03395	COG0154	amidase activity
LG951_03400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LG951_03405	COG1309	transcriptional regulator
LG951_03410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG951_03415	COG1957	nucleoside hydrolase
LG951_03420	COG1597	lipid kinase activity
LG951_03425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LG951_03435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LG951_03450	COG1959	2 iron, 2 sulfur cluster binding
LG951_03455	COG0492	ferredoxin-NADP+ reductase activity
LG951_03475	COG1486	melibiose metabolic process
LG951_03485	COG2211	Major facilitator Superfamily
LG951_03515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LG951_03520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LG951_03525	COG1442	glycosyl transferase family 8
LG951_03530	COG1216	Glycosyl transferase, family 2
LG951_03535	COG1442	glycosyl transferase family 8
LG951_03540	COG2223	nitrite transmembrane transporter activity
LG951_03550	COG0471	metal ion transport
LG951_03565	COG0071	Belongs to the small heat shock protein (HSP20) family
LG951_03580	COG0531	amino acid
LG951_03585	COG0463	Glycosyl transferase, family 2
LG951_03585	COG0457	Tetratricopeptide repeat
LG951_03590	COG0488	(ABC) transporter
LG951_03595	COG0789	Transcriptional regulator
LG951_03600	COG2814	Major facilitator Superfamily
LG951_03605	COG0488	(ABC) transporter
LG951_03610	COG0513	Belongs to the DEAD box helicase family
LG951_03615	COG2130	NADP-dependent
LG951_03635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LG951_03635	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LG951_03640	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LG951_03650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LG951_03650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LG951_03660	COG3290	protein histidine kinase activity
LG951_03665	COG4565	transcriptional regulatory protein
LG951_03670	COG3181	Tripartite tricarboxylate transporter family receptor
LG951_03675	COG2851	Citrate transporter
LG951_03685	COG3479	Phenolic acid decarboxylase
LG951_03690	COG1695	Transcriptional regulator
LG951_03695	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LG951_03700	COG1254	Belongs to the acylphosphatase family
LG951_03705	COG2258	MOSC domain
LG951_03720	COG0024	Methionine aminopeptidase
LG951_03725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG951_03725	COG1263	PTS System
LG951_03730	COG3739	integral membrane protein
LG951_03745	COG1368	sulfuric ester hydrolase activity
LG951_03750	COG0076	glutamate decarboxylase activity
LG951_03765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG951_03765	COG1263	PTS System
LG951_03770	COG0366	Alpha amylase catalytic
LG951_03775	COG2188	Transcriptional regulator
LG951_03785	COG0737	Belongs to the 5'-nucleotidase family
LG951_03790	COG0693	protein deglycase activity
LG951_03795	COG4840	Belongs to the UPF0435 family
LG951_03800	COG1115	amino acid carrier protein
LG951_03805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LG951_03810	COG4980	gas vesicle protein
LG951_03815	COG1295	ribonuclease BN
LG951_03825	COG0477	Major facilitator Superfamily
LG951_03835	COG0387	Pfam Sodium calcium exchanger
LG951_03845	COG0217	transcriptional regulatory protein
LG951_03850	COG0668	transmembrane transport
LG951_03855	COG0535	radical SAM domain protein
LG951_03865	COG0726	polysaccharide deacetylase
LG951_03875	COG0598	Magnesium transport protein CorA
LG951_03885	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LG951_03890	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LG951_03895	COG1309	transcriptional regulator
LG951_03900	COG1090	epimerase
LG951_03915	COG0789	Transcriptional regulator
LG951_03920	COG2814	Major facilitator Superfamily
LG951_03935	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LG951_03975	COG2076	Multidrug Resistance protein
LG951_03980	COG2076	Multidrug Resistance protein
LG951_03985	COG1309	transcriptional regulator
LG951_03995	COG4637	Psort location Cytoplasmic, score
LG951_04000	COG2755	lipolytic protein G-D-S-L family
LG951_04005	COG0492	ferredoxin-NADP+ reductase activity
LG951_04010	COG2207	Transcriptional regulator
LG951_04015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG951_04020	COG1132	(ABC) transporter
LG951_04025	COG1742	UPF0060 membrane protein
LG951_04030	COG1595	DNA-templated transcription, initiation
LG951_04050	COG2318	DinB family
LG951_04060	COG1846	Transcriptional regulator
LG951_04065	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LG951_04065	COG0392	lysyltransferase activity
LG951_04085	COG0778	Nitroreductase
LG951_04100	COG1090	epimerase
LG951_04105	COG2137	regulation of response to DNA damage stimulus
LG951_04130	COG0463	Glycosyl transferase, family 2
LG951_04135	COG4485	Bacterial membrane protein, YfhO
LG951_04140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LG951_04155	COG2140	Oxalate decarboxylase
LG951_04165	COG1191	sigma factor activity
LG951_04175	COG1988	membrane-bound metal-dependent
LG951_04180	COG1194	a g-specific adenine glycosylase
LG951_04190	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_04205	COG3557	Belongs to the UPF0374 family
LG951_04210	COG1132	(ABC) transporter
LG951_04215	COG0444	Belongs to the ABC transporter superfamily
LG951_04220	COG4608	Belongs to the ABC transporter superfamily
LG951_04225	COG0747	negative chemotaxis
LG951_04230	COG0601	transmembrane transport
LG951_04235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LG951_04240	COG4129	membrane
LG951_04245	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LG951_04250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LG951_04255	COG0735	belongs to the Fur family
LG951_04400	COG1368	sulfuric ester hydrolase activity
LG951_04405	COG0681	Belongs to the peptidase S26 family
LG951_04410	COG2873	o-acetylhomoserine
LG951_04420	COG1131	(ABC) transporter
LG951_04450	COG3382	B3 4 domain protein
LG951_04455	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LG951_04465	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LG951_04470	COG2766	serine protein kinase
LG951_04475	COG2718	Belongs to the UPF0229 family
LG951_04480	COG1566	PFAM secretion protein HlyD family protein
LG951_04485	COG2814	Major facilitator Superfamily
LG951_04490	COG0655	NAD(P)H dehydrogenase (quinone) activity
LG951_04500	COG1278	Cold shock
LG951_04505	COG3706	GGDEF domain
LG951_04530	COG5577	PFAM Coat F domain
LG951_04535	COG5002	protein histidine kinase activity
LG951_04540	COG4085	toxin activity
LG951_04540	COG0737	Belongs to the 5'-nucleotidase family
LG951_04540	COG1525	nuclease
LG951_04545	COG3764	Sortase (surface protein transpeptidase)
LG951_04550	COG0564	pseudouridine synthase activity
LG951_04560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LG951_04565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LG951_04565	COG3153	acetyltransferase
LG951_04580	COG3835	regulator
LG951_04585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LG951_04590	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LG951_04595	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LG951_04600	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LG951_04605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LG951_04610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LG951_04615	COG2203	Gaf domain
LG951_04615	COG4585	Histidine kinase
LG951_04620	COG2197	response regulator
LG951_04640	COG0753	catalase activity
LG951_04645	COG1959	2 iron, 2 sulfur cluster binding
LG951_04650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LG951_04650	COG1017	nitric oxide dioxygenase activity
LG951_04655	COG2719	SpoVR family
LG951_04660	COG1785	Belongs to the alkaline phosphatase family
LG951_04665	COG0791	NLP P60 protein
LG951_04665	COG1388	LysM domain
LG951_04680	COG1595	DNA-templated transcription, initiation
LG951_04685	COG0204	Acyl-transferase
LG951_04690	COG1253	flavin adenine dinucleotide binding
LG951_04695	COG0789	Transcriptional regulator
LG951_04700	COG1253	flavin adenine dinucleotide binding
LG951_04715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LG951_04720	COG0584	glycerophosphoryl diester phosphodiesterase
LG951_04730	COG0668	transmembrane transport
LG951_04735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LG951_04740	COG0726	polysaccharide deacetylase
LG951_04745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LG951_04750	COG0589	response to stress
LG951_04755	COG1132	(ABC) transporter
LG951_04760	COG1132	(ABC) transporter
LG951_04765	COG0702	epimerase
LG951_04775	COG3842	ATPase activity
LG951_04780	COG2508	Transcriptional regulator
LG951_04790	COG0189	ligase activity
LG951_04795	COG0189	ligase activity
LG951_04800	COG4399	Belongs to the UPF0754 family
LG951_04805	COG3679	Belongs to the UPF0342 family
LG951_04810	COG0561	phosphatase activity
LG951_04815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LG951_04830	COG1024	Enoyl-CoA hydratase
LG951_04840	COG0420	3'-5' exonuclease activity
LG951_04845	COG4717	serine-type aminopeptidase activity
LG951_04850	COG3481	metal-dependent phosphohydrolase, HD sub domain
LG951_04860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LG951_04890	COG1846	Transcriptional regulator
LG951_04895	COG4980	gas vesicle protein
LG951_04910	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LG951_04915	COG0537	adenosine 5'-monophosphoramidase activity
LG951_04920	COG1131	(ABC) transporter
LG951_04925	COG4473	ABC transporter
LG951_04935	COG1473	amidohydrolase
LG951_04945	COG2329	Antibiotic biosynthesis monooxygenase
LG951_04950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LG951_04955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LG951_04960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LG951_04965	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LG951_04970	COG1309	transcriptional regulator
LG951_04975	COG1511	domain protein
LG951_04980	COG1363	Peptidase, m42
LG951_04985	COG1301	dicarboxylic acid transport
LG951_04995	COG1234	tRNA 3'-trailer cleavage
LG951_05000	COG0095	Lipoate-protein ligase
LG951_05005	COG0318	PFAM AMP-dependent synthetase and ligase
LG951_05015	COG0501	Belongs to the peptidase M48B family
LG951_05020	COG1404	Belongs to the peptidase S8 family
LG951_05025	COG0406	alpha-ribazole phosphatase activity
LG951_05030	COG0840	transmembrane signaling receptor activity
LG951_05035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LG951_05035	COG0723	plastoquinol--plastocyanin reductase activity
LG951_05040	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_05060	COG2856	Zn peptidase
LG951_05070	COG1396	sequence-specific DNA binding
LG951_05110	COG5377	YqaJ viral recombinase family
LG951_05115	COG3723	Recombinational DNA repair protein, rece pathway
LG951_05125	COG1484	DNA-dependent DNA replication
LG951_05135	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
LG951_05210	COG3677	Transposase
LG951_05295	COG3953	SLT domain
LG951_05295	COG5412	phage tail tape measure protein
LG951_05360	COG1876	peptidase activity
LG951_05405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG951_05410	COG2814	Major facilitator Superfamily
LG951_05415	COG2732	(Barnase) inhibitor
LG951_05420	COG1316	TRANSCRIPTIONal
LG951_05430	COG0398	Pfam SNARE associated Golgi protein
LG951_05435	COG0681	Belongs to the peptidase S26 family
LG951_05440	COG3180	Ammonia monooxygenase
LG951_05450	COG0501	Belongs to the peptidase M48B family
LG951_05455	COG2259	Doxx family
LG951_05460	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LG951_05465	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LG951_05470	COG1074	ATP-dependent DNA helicase activity
LG951_05475	COG0420	3'-5' exonuclease activity
LG951_05480	COG0419	ATPase involved in DNA repair
LG951_05485	COG1403	HNH endonuclease
LG951_05525	COG5337	Spore coat protein CotH
LG951_05535	COG0179	Fumarylacetoacetate (FAA) hydrolase
LG951_05550	COG0367	asparagine synthase
LG951_05565	COG1562	ergosterol biosynthetic process
LG951_05570	COG0534	Mate efflux family protein
LG951_05575	COG1917	Cupin 2, conserved barrel domain protein
LG951_05575	COG2207	Transcriptional regulator
LG951_05605	COG0076	glutamate decarboxylase activity
LG951_05635	COG1410	methionine synthase
LG951_05635	COG0646	methionine synthase
LG951_05640	COG0646	methionine synthase
LG951_05640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LG951_05645	COG1666	GTP binding
LG951_05650	COG2996	Protein conserved in bacteria
LG951_05655	COG1744	ABC transporter substrate-binding protein PnrA-like
LG951_05660	COG0840	transmembrane signaling receptor activity
LG951_05665	COG1307	EDD domain protein, DegV family
LG951_05670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LG951_05690	COG0561	phosphatase activity
LG951_05695	COG1073	alpha beta
LG951_05700	COG2151	metal-sulfur cluster biosynthetic enzyme
LG951_05705	COG0277	FAD linked oxidase domain protein
LG951_05710	COG2271	Major facilitator Superfamily
LG951_05715	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LG951_05720	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LG951_05725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LG951_05730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LG951_05735	COG0505	Belongs to the CarA family
LG951_05740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LG951_05745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LG951_05755	COG2814	Major facilitator Superfamily
LG951_05765	COG2267	carboxylic ester hydrolase activity
LG951_05775	COG1744	ABC transporter substrate-binding protein PnrA-like
LG951_05790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LG951_05795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LG951_05800	COG5504	Zn-dependent protease
LG951_05805	COG0444	Belongs to the ABC transporter superfamily
LG951_05810	COG4608	Belongs to the ABC transporter superfamily
LG951_05820	COG0601	transmembrane transport
LG951_05825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LG951_05835	COG0180	Tryptophanyl-tRNA synthetase
LG951_05840	COG4166	transmembrane transport
LG951_05845	COG0601	transmembrane transport
LG951_05850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LG951_05855	COG0444	Belongs to the ABC transporter superfamily
LG951_05860	COG4608	Belongs to the ABC transporter superfamily
LG951_05870	COG0456	acetyltransferase
LG951_05875	COG1393	Belongs to the ArsC family
LG951_05880	COG0861	Integral membrane protein TerC family
LG951_05885	COG4862	establishment of competence for transformation
LG951_05890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LG951_05900	COG1164	Oligoendopeptidase f
LG951_05910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LG951_05915	COG2346	COG2346, Truncated hemoglobins
LG951_05920	COG0741	lytic transglycosylase activity
LG951_05925	COG4116	CYTH
LG951_05935	COG2357	RelA SpoT domain protein
LG951_05940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LG951_05945	COG0564	pseudouridine synthase activity
LG951_05950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LG951_05955	COG0475	glutathione-regulated potassium exporter activity
LG951_05955	COG0569	domain protein
LG951_05960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LG951_05965	COG0352	thiamine-phosphate diphosphorylase activity
LG951_05975	COG2104	thiamine diphosphate biosynthetic process
LG951_05980	COG2022	thiamine diphosphate biosynthetic process
LG951_05985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LG951_05990	COG0351	phosphomethylpyrimidine kinase
LG951_05995	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LG951_06050	COG0210	DNA helicase
LG951_06060	COG2153	protein acetylation
LG951_06065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LG951_06070	COG2382	esterase
LG951_06075	COG0626	cystathionine gamma-synthase activity
LG951_06080	COG0626	cystathionine gamma-synthase activity
LG951_06105	COG0604	alcohol dehydrogenase
LG951_06115	COG0113	porphobilinogen synthase activity
LG951_06120	COG0825	malonyl-CoA metabolic process
LG951_06135	COG1280	lysine exporter protein (LysE YggA)
LG951_06160	COG0457	Tetratricopeptide repeat
LG951_06180	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LG951_06190	COG0583	DNA-binding transcription factor activity
LG951_06205	COG0583	DNA-binding transcription factor activity
LG951_06210	COG2807	transmembrane transport
LG951_06235	COG0457	Tetratricopeptide repeat
LG951_06255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LG951_06265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LG951_06270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LG951_06290	COG4195	phage-related replication protein
LG951_06295	COG2856	Zn peptidase
LG951_06300	COG3409	Peptidoglycan-binding domain 1 protein
LG951_06300	COG5632	N-Acetylmuramoyl-L-alanine amidase
LG951_06315	COG0306	phosphate transporter
LG951_06320	COG1392	Phosphate transport regulator
LG951_06330	COG0405	Gamma-glutamyltransferase
LG951_06340	COG3775	system Galactitol-specific IIC component
LG951_06355	COG1063	alcohol dehydrogenase
LG951_06360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LG951_06365	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG951_06365	COG0022	dehydrogenase e1 component
LG951_06370	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG951_06375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LG951_06380	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_06385	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_06390	COG2390	Transcriptional regulator
LG951_06400	COG0531	amino acid
LG951_06405	COG0346	lactoylglutathione lyase activity
LG951_06410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG951_06415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LG951_06420	COG2362	D-Aminopeptidase
LG951_06425	COG0601	transmembrane transport
LG951_06430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LG951_06435	COG0444	Belongs to the ABC transporter superfamily
LG951_06440	COG4166	transmembrane transport
LG951_06445	COG1619	proteins homologs of microcin C7 resistance protein MccF
LG951_06450	COG4948	Mandelate Racemase Muconate Lactonizing
LG951_06455	COG0791	NLP P60 protein
LG951_06460	COG4608	Belongs to the ABC transporter superfamily
LG951_06465	COG1834	amidinotransferase
LG951_06470	COG1607	acyl-coa hydrolase
LG951_06475	COG1695	Transcriptional regulator
LG951_06490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LG951_06505	COG2076	Multidrug Resistance protein
LG951_06510	COG2076	Multidrug Resistance protein
LG951_06520	COG0788	formyltetrahydrofolate deformylase activity
LG951_06525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LG951_06530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LG951_06535	COG0457	Tetratricopeptide repeat
LG951_06545	COG1764	response to oxidative stress
LG951_06550	COG1846	Transcriptional regulator
LG951_06555	COG1764	response to oxidative stress
LG951_06560	COG0590	tRNA wobble adenosine to inosine editing
LG951_06565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LG951_06570	COG1404	Belongs to the peptidase S8 family
LG951_06575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LG951_06580	COG0745	RESPONSE REGULATOR receiver
LG951_06585	COG3850	Histidine kinase
LG951_06585	COG5002	protein histidine kinase activity
LG951_06590	COG3212	peptidase
LG951_06595	COG3212	peptidase
LG951_06600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LG951_06610	COG2239	Acts as a magnesium transporter
LG951_06620	COG0583	DNA-binding transcription factor activity
LG951_06630	COG0789	Transcriptional regulator
LG951_06645	COG1846	Transcriptional regulator
LG951_06650	COG3300	MHYT domain
LG951_06650	COG5001	Diguanylate cyclase
LG951_06655	COG0586	Pfam SNARE associated Golgi protein
LG951_06660	COG0861	Integral membrane protein TerC family
LG951_06665	COG1191	sigma factor activity
LG951_06685	COG0501	Belongs to the peptidase M48B family
LG951_06690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LG951_06695	COG2323	membrane
LG951_06710	COG3594	Acyltransferase
LG951_06715	COG5002	protein histidine kinase activity
LG951_06720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LG951_06725	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LG951_06730	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LG951_06735	COG0436	Aminotransferase
LG951_06740	COG1850	ribulose-bisphosphate carboxylase activity
LG951_06745	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LG951_06750	COG0235	Class ii aldolase
LG951_06755	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LG951_06765	COG3852	Histidine kinase
LG951_06770	COG1846	Transcriptional regulator
LG951_06775	COG1360	Flagellar Motor Protein
LG951_06780	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LG951_06785	COG0542	response to heat
LG951_06790	COG3949	Membrane
LG951_06795	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LG951_06800	COG0720	synthase
LG951_06805	COG0602	queuosine metabolic process
LG951_06810	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LG951_06820	COG4873	Protein conserved in bacteria
LG951_06830	COG3773	Cell wall hydrolase
LG951_06835	COG2244	polysaccharide biosynthetic process
LG951_06840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG951_06845	COG2217	Heavy metal translocating P-type atpase
LG951_06850	COG0006	proline dipeptidase activity
LG951_06860	COG1609	Transcriptional regulator
LG951_06865	COG3711	transcriptional antiterminator
LG951_06870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG951_06870	COG2190	(PTS) system
LG951_06870	COG1263	PTS System
LG951_06875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG951_06880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LG951_06890	COG1533	DNA photolyase activity
LG951_06895	COG0840	transmembrane signaling receptor activity
LG951_06905	COG2084	Dehydrogenase
LG951_06910	COG2340	Cysteine-rich secretory protein family
LG951_06915	COG0768	penicillin binding
LG951_06925	COG0436	Aminotransferase
LG951_06930	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LG951_06940	COG1714	RDD family
LG951_06950	COG0835	chemotaxis
LG951_06950	COG0784	Response regulator, receiver
LG951_06960	COG1917	Cupin 2, conserved barrel domain protein
LG951_06960	COG2207	Transcriptional regulator
LG951_06965	COG0697	spore germination
LG951_06975	COG2814	Major facilitator Superfamily
LG951_06980	COG1376	ErfK ybiS ycfS ynhG family protein
LG951_06985	COG1408	metallophosphoesterase
LG951_06990	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_06995	COG2200	EAL domain
LG951_07000	COG3546	catalase activity
LG951_07005	COG4703	Protein of unknown function (DUF1797)
LG951_07010	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LG951_07020	COG0517	IMP dehydrogenase activity
LG951_07025	COG0583	DNA-binding transcription factor activity
LG951_07035	COG0716	FMN binding
LG951_07045	COG0716	FMN binding
LG951_07050	COG2171	N-acyltransferase activity
LG951_07055	COG1473	amidohydrolase
LG951_07065	COG0668	transmembrane transport
LG951_07070	COG0450	alkyl hydroperoxide reductase
LG951_07075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG951_07090	COG0746	molybdenum cofactor guanylyltransferase activity
LG951_07095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LG951_07100	COG0303	'Molybdopterin
LG951_07105	COG1763	Mo-molybdopterin cofactor biosynthetic process
LG951_07110	COG0314	molybdopterin synthase activity
LG951_07115	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LG951_07130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG951_07135	COG1136	(ABC) transporter
LG951_07140	COG0577	efflux transmembrane transporter activity
LG951_07145	COG1349	DNA-binding transcription factor activity
LG951_07150	COG1105	Belongs to the carbohydrate kinase PfkB family
LG951_07155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG951_07155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG951_07155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG951_07160	COG0681	Belongs to the peptidase S26 family
LG951_07170	COG0488	(ABC) transporter
LG951_07175	COG2309	aminopeptidase activity
LG951_07185	COG1077	Cell shape determining protein MreB Mrl
LG951_07190	COG2002	toxin-antitoxin pair type II binding
LG951_07195	COG3852	Histidine kinase
LG951_07200	COG2105	PFAM AIG2 family protein
LG951_07200	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LG951_07205	COG0569	domain protein
LG951_07210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LG951_07215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LG951_07220	COG5503	Protein of unknown function (DUF1447)
LG951_07225	COG0561	phosphatase activity
LG951_07230	COG0242	peptide deformylase activity
LG951_07245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LG951_07250	COG0022	dehydrogenase e1 component
LG951_07255	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG951_07260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LG951_07265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG951_07275	COG1982	Orn Lys Arg decarboxylase major
LG951_07280	COG4476	Belongs to the UPF0223 family
LG951_07285	COG4493	Belongs to the UPF0637 family
LG951_07295	COG0483	inositol monophosphate 1-phosphatase activity
LG951_07310	COG1595	DNA-templated transcription, initiation
LG951_07330	COG1217	gtp-binding protein TYPA
LG951_07340	COG4896	Protein conserved in bacteria
LG951_07350	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LG951_07355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LG951_07360	COG2066	Belongs to the glutaminase family
LG951_07365	COG4838	Belongs to the UPF0358 family
LG951_07370	COG0772	Belongs to the SEDS family
LG951_07375	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LG951_07380	COG0415	Belongs to the DNA photolyase family
LG951_07385	COG1612	heme a metabolic process
LG951_07390	COG0109	protoheme IX farnesyltransferase activity
LG951_07395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LG951_07395	COG2010	Cytochrome c
LG951_07400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LG951_07405	COG1845	cytochrome c oxidase, subunit III
LG951_07410	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LG951_07415	COG3336	cytochrome c oxidase
LG951_07425	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LG951_07430	COG2340	Cysteine-rich secretory protein family
LG951_07450	COG3679	Belongs to the UPF0342 family
LG951_07455	COG4471	UPF0298 protein
LG951_07460	COG0742	ribosomal rna small subunit methyltransferase
LG951_07465	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LG951_07470	COG3314	Sporulation integral membrane protein YlbJ
LG951_07475	COG1752	Esterase of the alpha-beta hydrolase superfamily
LG951_07480	COG3480	Lon protease (S16) C-terminal proteolytic domain
LG951_07490	COG1399	metal-binding, possibly nucleic acid-binding protein
LG951_07495	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LG951_07505	COG0454	-acetyltransferase
LG951_07510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LG951_07515	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LG951_07520	COG2001	Belongs to the MraZ family
LG951_07525	COG0275	rRNA processing
LG951_07530	COG4839	cell division protein FtsL
LG951_07535	COG0768	penicillin binding
LG951_07540	COG0768	penicillin binding
LG951_07545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LG951_07550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LG951_07555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LG951_07560	COG0772	Belongs to the SEDS family
LG951_07565	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LG951_07570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LG951_07575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LG951_07580	COG3879	Bacterial protein of unknown function (DUF881)
LG951_07585	COG3879	Bacterial protein of unknown function (DUF881)
LG951_07590	COG3856	small basic protein
LG951_07595	COG0849	cell division
LG951_07600	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LG951_07605	COG1404	Belongs to the peptidase S8 family
LG951_07605	COG4412	M6 family metalloprotease domain protein
LG951_07615	COG1191	sigma factor activity
LG951_07620	COG1191	sigma factor activity
LG951_07625	COG2390	Transcriptional regulator
LG951_07640	COG3730	PTS system glucitol sorbitol-specific
LG951_07645	COG3732	PTS system glucitol sorbitol-specific
LG951_07655	COG1119	ATPase activity
LG951_07660	COG1873	PFAM PRC-barrel domain
LG951_07665	COG1496	oxidoreductase activity
LG951_07670	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LG951_07675	COG1799	cell septum assembly
LG951_07680	COG0762	integral membrane protein
LG951_07685	COG2302	S4 RNA-binding domain
LG951_07690	COG3599	regulation of cell shape
LG951_07695	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LG951_07700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LG951_07705	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LG951_07710	COG0564	pseudouridine synthase activity
LG951_07715	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LG951_07720	COG2233	PERMEase
LG951_07725	COG0540	Belongs to the ATCase OTCase family
LG951_07730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LG951_07735	COG0505	Belongs to the CarA family
LG951_07740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LG951_07745	COG0543	2 iron, 2 sulfur cluster binding
LG951_07750	COG0167	dihydroorotate dehydrogenase activity
LG951_07755	COG0284	orotidine-5'-phosphate decarboxylase activity
LG951_07760	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LG951_07770	COG0175	sulfate reduction
LG951_07775	COG0306	phosphate transporter
LG951_07780	COG2046	Belongs to the sulfate adenylyltransferase family
LG951_07785	COG0529	Catalyzes the synthesis of activated sulfate
LG951_07790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LG951_07795	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
LG951_07800	COG1648	precorrin-2 dehydrogenase activity
LG951_07805	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LG951_07810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LG951_07815	COG1561	YicC-like family, N-terminal region
LG951_07820	COG2052	Domain of unknown function (DUF370)
LG951_07825	COG0194	GDP metabolic process
LG951_07830	COG1758	RNA polymerase activity
LG951_07835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LG951_07840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LG951_07845	COG0242	peptide deformylase activity
LG951_07850	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LG951_07855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LG951_07855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LG951_07860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LG951_07865	COG0631	protein serine/threonine phosphatase activity
LG951_07870	COG2815	serine threonine protein kinase
LG951_07870	COG0515	serine threonine protein kinase
LG951_07875	COG1162	GTPase activity
LG951_07880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LG951_07885	COG1564	THIamine pyrophosphokinase
LG951_07895	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LG951_07900	COG1302	Protein conserved in bacteria
LG951_07905	COG1461	Dihydroxyacetone kinase
LG951_07910	COG1760	l-serine dehydratase
LG951_07915	COG1760	l-serine dehydratase
LG951_07920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LG951_07925	COG1349	DNA-binding transcription factor activity
LG951_07930	COG0416	fatty acid biosynthetic process
LG951_07935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LG951_07940	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_07945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LG951_07955	COG1196	nuclear chromosome segregation
LG951_07960	COG0552	protein localization to endoplasmic reticulum
LG951_07965	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LG951_07970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LG951_07975	COG0228	four-way junction DNA binding
LG951_07980	COG1837	Belongs to the UPF0109 family
LG951_07990	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LG951_07995	COG0336	Belongs to the RNA methyltransferase TrmD family
LG951_08000	COG0335	large ribosomal subunit rRNA binding
LG951_08005	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LG951_08010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LG951_08020	COG2257	FlhB HrpN YscU SpaS Family
LG951_08025	COG0045	succinate-CoA ligase (ADP-forming) activity
LG951_08030	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LG951_08035	COG0758	DNA mediated transformation
LG951_08040	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LG951_08045	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LG951_08050	COG4974	Belongs to the 'phage' integrase family
LG951_08055	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LG951_08060	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LG951_08065	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LG951_08070	COG1815	bacterial-type flagellum-dependent cell motility
LG951_08075	COG1558	bacterial-type flagellum-dependent cell motility
LG951_08080	COG1677	Flagellar hook-basal body complex protein FliE
LG951_08085	COG1766	The M ring may be actively involved in energy transduction
LG951_08090	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LG951_08095	COG1317	bacterial-type flagellum organization
LG951_08100	COG1157	protein secretion by the type III secretion system
LG951_08105	COG2882	bacterial-type flagellum organization
LG951_08110	COG3334	PFAM MgtE intracellular
LG951_08115	COG3144	bacterial-type flagellum assembly
LG951_08120	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LG951_08125	COG4786	Flagellar basal body rod
LG951_08130	COG1582	Flagellar protein (FlbD)
LG951_08135	COG1580	Controls the rotational direction of flagella during chemotaxis
LG951_08140	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LG951_08145	COG1776	CheC inhibitor of MCP methylation
LG951_08145	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LG951_08150	COG2201	protein-glutamate methylesterase activity
LG951_08155	COG3190	flagellar
LG951_08160	COG1338	Plays a role in the flagellum-specific transport system
LG951_08165	COG1987	bacterial-type flagellum assembly
LG951_08170	COG1684	flagellar biosynthetic protein fliR
LG951_08175	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LG951_08180	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LG951_08185	COG1419	protein localization to endoplasmic reticulum
LG951_08190	COG0455	bacterial-type flagellum organization
LG951_08195	COG2201	protein-glutamate methylesterase activity
LG951_08200	COG2198	Histidine kinase
LG951_08200	COG0643	Histidine kinase
LG951_08205	COG0835	chemotaxis
LG951_08210	COG1776	CheC inhibitor of MCP methylation
LG951_08220	COG1191	sigma factor activity
LG951_08230	COG0052	Belongs to the universal ribosomal protein uS2 family
LG951_08235	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LG951_08240	COG0528	UMP kinase activity
LG951_08245	COG0233	cytoplasmic translational termination
LG951_08250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LG951_08255	COG4589	Belongs to the CDS family
LG951_08260	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LG951_08265	COG0750	zinc metalloprotease
LG951_08270	COG0442	prolyl-tRNA aminoacylation
LG951_08275	COG2176	DNA-directed DNA polymerase activity
LG951_08290	COG3693	PFAM glycoside hydrolase, family 10
LG951_08310	COG1131	(ABC) transporter
LG951_08325	COG0779	Required for maturation of 30S ribosomal subunits
LG951_08330	COG0195	Participates in both transcription termination and antitermination
LG951_08335	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LG951_08340	COG1358	cellular component organization or biogenesis
LG951_08345	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LG951_08350	COG1550	Protein conserved in bacteria
LG951_08355	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LG951_08360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LG951_08365	COG0196	riboflavin kinase activity
LG951_08370	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LG951_08375	COG1185	polyribonucleotide nucleotidyltransferase activity
LG951_08380	COG0726	polysaccharide deacetylase
LG951_08385	COG0612	Peptidase, M16
LG951_08395	COG1873	PFAM PRC-barrel domain
LG951_08400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LG951_08405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LG951_08410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LG951_08415	COG0527	aspartate kinase activity
LG951_08425	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LG951_08430	COG0740	serine-type endopeptidase activity
LG951_08440	COG1674	ftsk spoiiie
LG951_08440	COG4980	gas vesicle protein
LG951_08445	COG2188	Transcriptional regulator
LG951_08450	COG2814	Major facilitator Superfamily
LG951_08455	COG1033	growth of symbiont in host cell
LG951_08455	COG2409	Drug exporters of the RND superfamily
LG951_08460	COG0612	Peptidase, M16
LG951_08465	COG0612	Peptidase, M16
LG951_08475	COG2409	Drug exporters of the RND superfamily
LG951_08475	COG1033	growth of symbiont in host cell
LG951_08480	COG0300	oxidoreductase activity
LG951_08495	COG1426	Protein conserved in bacteria
LG951_08500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LG951_08505	COG1546	Belongs to the CinA family
LG951_08505	COG1058	Belongs to the CinA family
LG951_08510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LG951_08515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LG951_08520	COG1418	mRNA catabolic process
LG951_08525	COG1692	metallophosphoesterase
LG951_08530	COG2359	stage V sporulation protein S
LG951_08535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG951_08540	COG1063	alcohol dehydrogenase
LG951_08545	COG0156	8-amino-7-oxononanoate synthase activity
LG951_08550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LG951_08555	COG4550	Control of competence regulator ComK, YlbF/YmcA
LG951_08565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LG951_08570	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LG951_08585	COG1329	Transcriptional regulator
LG951_08590	COG4195	phage-related replication protein
LG951_08595	COG0457	Tetratricopeptide repeat
LG951_08600	COG1404	Belongs to the peptidase S8 family
LG951_08605	COG4195	phage-related replication protein
LG951_08610	COG1764	response to oxidative stress
LG951_08615	COG2076	Multidrug Resistance protein
LG951_08640	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LG951_08645	COG1923	regulation of RNA biosynthetic process
LG951_08660	COG1780	Probably involved in ribonucleotide reductase function
LG951_08665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LG951_08670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LG951_08675	COG4112	unkown
LG951_08685	COG0464	growth
LG951_08690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LG951_08695	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LG951_08700	COG0789	Transcriptional regulator
LG951_08705	COG0174	glutamine synthetase
LG951_08710	COG0741	lytic transglycosylase activity
LG951_08710	COG1196	nuclear chromosome segregation
LG951_08710	COG0739	heme binding
LG951_08735	COG0457	Tetratricopeptide repeat
LG951_08740	COG5444	nuclease activity
LG951_08755	COG5444	nuclease activity
LG951_08780	COG5646	InterPro IPR014922
LG951_08790	COG0457	Tetratricopeptide repeat
LG951_08800	COG3619	membrane
LG951_08805	COG1793	dna ligase
LG951_08805	COG3285	dna ligase
LG951_08810	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LG951_08815	COG4876	unkown
LG951_08820	COG0346	lactoylglutathione lyase activity
LG951_08825	COG1959	2 iron, 2 sulfur cluster binding
LG951_08830	COG0702	epimerase
LG951_08840	COG0247	lactate metabolic process
LG951_08845	COG1139	Iron-sulfur cluster binding protein
LG951_08850	COG1556	Lactate utilization protein
LG951_08855	COG0697	spore germination
LG951_08870	COG2323	membrane
LG951_08875	COG1309	transcriptional regulator
LG951_08880	COG2124	cytochrome p450
LG951_08880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LG951_08885	COG3591	Belongs to the peptidase S1B family
LG951_08890	COG3209	COG3209 Rhs family protein
LG951_08895	COG1366	Belongs to the anti-sigma-factor antagonist family
LG951_08910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LG951_08915	COG1388	LysM domain
LG951_08920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LG951_08925	COG4224	UPF0291 protein
LG951_08930	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LG951_08940	COG3763	UPF0154 protein
LG951_08950	COG0785	Cytochrome C biogenesis protein
LG951_08955	COG4846	Membrane protein involved in cytochrome C biogenesis
LG951_08965	COG0071	Belongs to the small heat shock protein (HSP20) family
LG951_08980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LG951_08985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG951_09005	COG0824	Thioesterase
LG951_09015	COG4841	protein insertion into membrane
LG951_09020	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LG951_09025	COG1832	CoA-binding protein
LG951_09030	COG0187	DNA topoisomerase II activity
LG951_09035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LG951_09045	COG0738	Major facilitator superfamily
LG951_09075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LG951_09080	COG0251	oxidation-reduction process
LG951_09120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LG951_09150	COG0657	acetylesterase activity
LG951_09165	COG2205	protein histidine kinase activity
LG951_09170	COG0745	RESPONSE REGULATOR receiver
LG951_09180	COG3507	Belongs to the glycosyl hydrolase 43 family
LG951_09185	COG1012	belongs to the aldehyde dehydrogenase family
LG951_09190	COG1486	melibiose metabolic process
LG951_09195	COG0395	ABC-type sugar transport system, permease component
LG951_09200	COG1175	transmembrane transport
LG951_09205	COG1653	transport
LG951_09210	COG1609	Transcriptional regulator
LG951_09215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LG951_09230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG951_09240	COG5444	nuclease activity
LG951_09245	COG1846	Transcriptional regulator
LG951_09250	COG2814	Major facilitator Superfamily
LG951_09260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG951_09260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG951_09260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG951_09265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG951_09265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG951_09265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG951_09270	COG1105	Belongs to the carbohydrate kinase PfkB family
LG951_09280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LG951_09310	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LG951_09315	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LG951_09320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LG951_09325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LG951_09330	COG1024	Enoyl-CoA hydratase
LG951_09335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LG951_09340	COG0511	ligase activity, forming carbon-carbon bonds
LG951_09345	COG0439	Biotin carboxylase
LG951_09350	COG0318	PFAM AMP-dependent synthetase and ligase
LG951_09355	COG1960	acyl-CoA dehydrogenase activity
LG951_09360	COG1649	PFAM Uncharacterised BCR, COG1649
LG951_09365	COG2365	Tyrosine phosphatase family
LG951_09370	COG1349	DNA-binding transcription factor activity
LG951_09380	COG3835	regulator
LG951_09385	COG0277	FAD linked oxidase domain protein
LG951_09390	COG0247	lactate metabolic process
LG951_09415	COG0166	Belongs to the GPI family
LG951_09420	COG0586	Pfam SNARE associated Golgi protein
LG951_09425	COG1587	Uroporphyrinogen-III synthase
LG951_09435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG951_09465	COG0534	Mate efflux family protein
LG951_09470	COG2027	D-alanyl-D-alanine carboxypeptidase
LG951_09475	COG4677	pectinesterase activity
LG951_09480	COG2323	membrane
LG951_09485	COG0493	'glutamate synthase
LG951_09490	COG0069	glutamate synthase activity
LG951_09490	COG0067	glutamate synthase
LG951_09490	COG0070	glutamate synthase
LG951_09495	COG0583	DNA-binding transcription factor activity
LG951_09515	COG0454	-acetyltransferase
LG951_09520	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LG951_09525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LG951_09540	COG0243	molybdopterin cofactor binding
LG951_09550	COG1070	Carbohydrate kinase
LG951_09555	COG2115	Belongs to the xylose isomerase family
LG951_09560	COG1940	carbohydrate kinase activity
LG951_09570	COG2211	Major facilitator Superfamily
LG951_09575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG951_09580	COG1994	Peptidase M50
LG951_09600	COG1309	transcriptional regulator
LG951_09605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG951_09610	COG3708	Transcriptional regulator
LG951_09615	COG2378	regulation of single-species biofilm formation
LG951_09625	COG0640	Transcriptional regulator
LG951_09630	COG0531	amino acid
LG951_09635	COG0741	lytic transglycosylase activity
LG951_09640	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LG951_09645	COG2079	MmgE PrpD family protein
LG951_09650	COG0372	Belongs to the citrate synthase family
LG951_09655	COG2322	membrane
LG951_09665	COG1388	LysM domain
LG951_09665	COG3584	3D domain protein
LG951_09670	COG0514	ATP-dependent DNA helicase (RecQ)
LG951_09680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LG951_09705	COG1012	belongs to the aldehyde dehydrogenase family
LG951_09710	COG1657	PFAM Prenyltransferase squalene oxidase
LG951_09715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LG951_09720	COG0385	Bile acid
LG951_09725	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG951_09730	COG0567	Dehydrogenase, E1 component
LG951_09735	COG4548	von Willebrand factor, type A
LG951_09740	COG0714	Associated with various cellular activities
LG951_09745	COG2032	superoxide dismutase activity
LG951_09750	COG0791	NLP P60 protein
LG951_09750	COG1388	LysM domain
LG951_09755	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LG951_09760	COG0534	Mate efflux family protein
LG951_09765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LG951_09770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LG951_09780	COG2962	Rard protein
LG951_09795	COG1733	regulation of RNA biosynthetic process
LG951_09800	COG0778	Nitroreductase
LG951_09810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LG951_09815	COG0793	Belongs to the peptidase S41A family
LG951_09815	COG3409	Peptidoglycan-binding domain 1 protein
LG951_09820	COG2226	methyltransferase
LG951_09830	COG1876	peptidase activity
LG951_09835	COG0813	purine-nucleoside phosphorylase activity
LG951_09845	COG0671	phosphoesterase, PA-phosphatase related
LG951_09860	COG4479	Belongs to the UPF0346 family
LG951_09870	COG1509	lysine 2,3-aminomutase activity
LG951_09875	COG3829	transcription factor binding
LG951_09885	COG0463	Glycosyl transferase, family 2
LG951_09900	COG4641	Protein conserved in bacteria
LG951_09910	COG1086	Polysaccharide biosynthesis protein
LG951_09915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LG951_09920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LG951_09925	COG1846	Transcriptional regulator
LG951_09945	COG4698	Protein conserved in bacteria
LG951_09950	COG2755	lipolytic protein G-D-S-L family
LG951_09955	COG1999	signal sequence binding
LG951_09970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LG951_09975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LG951_09980	COG1272	protein, Hemolysin III
LG951_09985	COG0204	Acyl-transferase
LG951_09990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LG951_09995	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LG951_10000	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LG951_10010	COG2136	Putative SAM-dependent methyltransferase
LG951_10010	COG2521	methyltransferase
LG951_10020	COG0129	dihydroxy-acid dehydratase activity
LG951_10025	COG1413	lyase activity
LG951_10030	COG1418	mRNA catabolic process
LG951_10035	COG0386	Belongs to the glutathione peroxidase family
LG951_10040	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LG951_10045	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LG951_10050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LG951_10060	COG1278	Cold shock
LG951_10075	COG0328	RNA-DNA hybrid ribonuclease activity
LG951_10080	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LG951_10085	COG0328	RNA-DNA hybrid ribonuclease activity
LG951_10095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LG951_10105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LG951_10115	COG1755	Isoprenylcysteine carboxyl methyltransferase
LG951_10120	COG3424	synthase
LG951_10125	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LG951_10135	COG0726	polysaccharide deacetylase
LG951_10140	COG2233	PERMEase
LG951_10145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LG951_10150	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LG951_10155	COG1199	ATP-dependent helicase activity
LG951_10165	COG0116	Belongs to the methyltransferase superfamily
LG951_10175	COG3599	regulation of cell shape
LG951_10180	COG4474	Belongs to the UPF0398 family
LG951_10195	COG1012	belongs to the aldehyde dehydrogenase family
LG951_10210	COG2186	Transcriptional regulator
LG951_10215	COG0277	FAD linked oxidase domain protein
LG951_10220	COG0247	lactate metabolic process
LG951_10225	COG1902	pentaerythritol trinitrate reductase activity
LG951_10230	COG2190	(PTS) system
LG951_10235	COG0071	Belongs to the small heat shock protein (HSP20) family
LG951_10265	COG3331	DNA recombination
LG951_10270	COG4499	WXG100 protein secretion system (Wss), protein YukC
LG951_10270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LG951_10280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LG951_10285	COG3935	DnaD domain protein
LG951_10290	COG0017	Asparaginyl-tRNA synthetase
LG951_10295	COG5353	protein conserved in bacteria
LG951_10305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LG951_10305	COG1199	ATP-dependent helicase activity
LG951_10310	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LG951_10315	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LG951_10320	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LG951_10330	COG0617	tRNA 3'-terminal CCA addition
LG951_10335	COG0438	transferase activity, transferring glycosyl groups
LG951_10340	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LG951_10345	COG1803	Methylglyoxal synthase
LG951_10350	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LG951_10355	COG1694	Mazg nucleotide pyrophosphohydrolase
LG951_10360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LG951_10370	COG4347	Protein of unknown function (DUF1405)
LG951_10375	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LG951_10375	COG2010	Cytochrome c
LG951_10380	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LG951_10385	COG0723	plastoquinol--plastocyanin reductase activity
LG951_10395	COG5582	Belongs to the UPF0302 family
LG951_10400	COG0457	Tetratricopeptide repeat
LG951_10405	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LG951_10410	COG0287	Prephenate dehydrogenase
LG951_10415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LG951_10420	COG0159	tryptophan synthase activity
LG951_10425	COG0133	tryptophan synthase activity
LG951_10430	COG0135	phosphoribosylanthranilate isomerase activity
LG951_10435	COG0134	indole-3-glycerol-phosphate synthase activity
LG951_10440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LG951_10450	COG4401	Chorismate mutase type I
LG951_10455	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LG951_10460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LG951_10465	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LG951_10470	COG0105	UTP biosynthetic process
LG951_10475	COG0142	geranyltranstransferase activity
LG951_10480	COG2226	methyltransferase
LG951_10485	COG0142	geranyltranstransferase activity
LG951_10495	COG0302	gtp cyclohydrolase
LG951_10500	COG0776	regulation of translation
LG951_10505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LG951_10520	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LG951_10525	COG1160	GTP binding
LG951_10550	COG1304	FMN binding
LG951_10555	COG0539	negative regulation of cytoplasmic translation
LG951_10560	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LG951_10570	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LG951_10575	COG2959	enzyme of heme biosynthesis
LG951_10580	COG3409	Peptidoglycan-binding domain 1 protein
LG951_10580	COG3773	Cell wall hydrolase
LG951_10585	COG2339	peptidase activity
LG951_10590	COG0492	ferredoxin-NADP+ reductase activity
LG951_10595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LG951_10600	COG4862	establishment of competence for transformation
LG951_10605	COG1408	metallophosphoesterase
LG951_10615	COG1388	LysM domain
LG951_10620	COG1266	CAAX protease self-immunity
LG951_10625	COG0514	ATP-dependent DNA helicase (RecQ)
LG951_10630	COG4955	Helix-turn-helix domain
LG951_10635	COG1141	Ferredoxin
LG951_10640	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LG951_10645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LG951_10650	COG5632	N-Acetylmuramoyl-L-alanine amidase
LG951_10650	COG3409	Peptidoglycan-binding domain 1 protein
LG951_10660	COG1595	DNA-templated transcription, initiation
LG951_10665	COG5002	protein histidine kinase activity
LG951_10670	COG0745	RESPONSE REGULATOR receiver
LG951_10675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LG951_10680	COG1333	cytochrome c biogenesis protein
LG951_10685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG951_10690	COG1187	pseudouridine synthase activity
LG951_10695	COG0700	Nucleoside recognition
LG951_10700	COG2715	membrane protein required for spore maturation
LG951_10705	COG1686	Belongs to the peptidase S11 family
LG951_10715	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LG951_10720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LG951_10730	COG1547	Domain of unknown function (DUF309)
LG951_10735	COG0456	acetyltransferase
LG951_10740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LG951_10750	COG0307	riboflavin synthase, alpha
LG951_10770	COG2814	Major facilitator Superfamily
LG951_10775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LG951_10780	COG4086	secreted protein
LG951_10785	COG0019	diaminopimelate decarboxylase activity
LG951_10790	COG0697	spore germination
LG951_10805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LG951_10825	COG1191	sigma factor activity
LG951_10830	COG2172	sigma factor antagonist activity
LG951_10840	COG1686	Belongs to the peptidase S11 family
LG951_10845	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LG951_10850	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LG951_10855	COG4974	Belongs to the 'phage' integrase family
LG951_10865	COG0735	belongs to the Fur family
LG951_10870	COG1300	Membrane
LG951_10875	COG1404	Belongs to the peptidase S8 family
LG951_10885	COG2153	protein acetylation
LG951_10890	COG1379	DNA repair
LG951_10895	COG0494	nUDIX hydrolase
LG951_10900	COG0667	Aldo Keto reductase
LG951_10915	COG1073	alpha beta
LG951_10920	COG0457	Tetratricopeptide repeat
LG951_10930	COG4918	Iron-sulphur cluster biosynthesis
LG951_10935	COG4305	rare lipoprotein A
LG951_10940	COG0456	acetyltransferase
LG951_10940	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LG951_10945	COG0456	acetyltransferase
LG951_10955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LG951_10965	COG2211	Major facilitator Superfamily
LG951_10970	COG1072	(Pantothenic acid kinase))
LG951_10975	COG0446	pyridine nucleotide-disulphide oxidoreductase
LG951_10980	COG0300	oxidoreductase activity
LG951_10985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG951_10990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LG951_11000	COG4187	Peptidase family M20/M25/M40
LG951_11005	COG1902	pentaerythritol trinitrate reductase activity
LG951_11010	COG0596	Alpha beta hydrolase
LG951_11015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG951_11020	COG1234	tRNA 3'-trailer cleavage
LG951_11025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LG951_11030	COG2188	Transcriptional regulator
LG951_11035	COG2723	6-phospho-beta-galactosidase activity
LG951_11040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LG951_11045	COG1447	Phosphotransferase system cellobiose-specific component IIA
LG951_11050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LG951_11055	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_11060	COG4975	Glucose uptake
LG951_11065	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LG951_11070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LG951_11080	COG0706	membrane insertase activity
LG951_11090	COG2195	Cleaves the N-terminal amino acid of tripeptides
LG951_11095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LG951_11100	COG0346	lactoylglutathione lyase activity
LG951_11110	COG1376	ErfK ybiS ycfS ynhG family protein
LG951_11115	COG4129	membrane
LG951_11120	COG1126	abc transporter atp-binding protein
LG951_11125	COG0765	amino acid transport
LG951_11130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG951_11140	COG1597	lipid kinase activity
LG951_11150	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG951_11155	COG0022	dehydrogenase e1 component
LG951_11160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LG951_11165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LG951_11170	COG3426	butyrate kinase activity
LG951_11175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LG951_11180	COG0280	phosphate acetyltransferase
LG951_11185	COG3290	protein histidine kinase activity
LG951_11185	COG3829	transcription factor binding
LG951_11195	COG0584	glycerophosphoryl diester phosphodiesterase
LG951_11200	COG0457	Tetratricopeptide repeat
LG951_11210	COG0745	RESPONSE REGULATOR receiver
LG951_11215	COG0750	zinc metalloprotease
LG951_11220	COG0497	DNA recombination
LG951_11225	COG1438	arginine binding
LG951_11230	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LG951_11235	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LG951_11240	COG0142	geranyltranstransferase activity
LG951_11245	COG1722	exodeoxyribonuclease VII activity
LG951_11250	COG1570	exodeoxyribonuclease VII activity
LG951_11255	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LG951_11260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LG951_11265	COG1302	Protein conserved in bacteria
LG951_11270	COG0439	Biotin carboxylase
LG951_11275	COG0511	ligase activity, forming carbon-carbon bonds
LG951_11315	COG3854	ATPases associated with a variety of cellular activities
LG951_11325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LG951_11330	COG0006	proline dipeptidase activity
LG951_11335	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LG951_11345	COG3872	metal-dependent enzyme
LG951_11355	COG1752	Esterase of the alpha-beta hydrolase superfamily
LG951_11360	COG1321	iron dependent repressor
LG951_11365	COG0095	Lipoate-protein ligase
LG951_11370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LG951_11375	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LG951_11380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LG951_11385	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LG951_11390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LG951_11405	COG1396	sequence-specific DNA binding
LG951_11415	COG0681	Belongs to the peptidase S26 family
LG951_11445	COG4970	Tfp pilus assembly protein FimT
LG951_11450	COG4537	Required for transformation and DNA binding
LG951_11455	COG1459	type II secretion system
LG951_11460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LG951_11465	COG1366	Belongs to the anti-sigma-factor antagonist family
LG951_11475	COG1393	Belongs to the ArsC family
LG951_11485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG951_11495	COG0011	TIGRFAM Protein of
LG951_11500	COG2814	Major facilitator Superfamily
LG951_11505	COG2866	Carboxypeptidase
LG951_11510	COG1368	sulfuric ester hydrolase activity
LG951_11515	COG1940	carbohydrate kinase activity
LG951_11520	COG4483	Protein conserved in bacteria
LG951_11525	COG0457	Tetratricopeptide repeat
LG951_11525	COG0705	Rhomboid family
LG951_11540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LG951_11545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LG951_11555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LG951_11560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LG951_11565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LG951_11570	COG0581	inorganic phosphate transmembrane transporter activity
LG951_11575	COG0573	inorganic phosphate transmembrane transporter activity
LG951_11580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LG951_11585	COG0768	penicillin binding
LG951_11590	COG0477	Major facilitator Superfamily
LG951_11595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LG951_11600	COG2839	Protein conserved in bacteria
LG951_11605	COG5521	maltodextrose utilization protein MalA
LG951_11610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LG951_11615	COG1388	LysM domain
LG951_11620	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LG951_11625	COG4709	membrane
LG951_11630	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LG951_11635	COG1940	carbohydrate kinase activity
LG951_11640	COG0735	belongs to the Fur family
LG951_11645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LG951_11650	COG1121	(ABC) transporter
LG951_11655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LG951_11665	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LG951_11670	COG0513	Belongs to the DEAD box helicase family
LG951_11680	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LG951_11685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LG951_11690	COG2384	SAM-dependent methyltransferase
LG951_11695	COG2010	Cytochrome c
LG951_11700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LG951_11705	COG0358	DNA primase activity
LG951_11710	COG1671	Belongs to the UPF0178 family
LG951_11715	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LG951_11720	COG0517	IMP dehydrogenase activity
LG951_11725	COG0751	glycine-tRNA ligase activity
LG951_11730	COG0752	glycyl-tRNA synthetase alpha subunit
LG951_11735	COG1381	Involved in DNA repair and RecF pathway recombination
LG951_11745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LG951_11750	COG0295	cytidine deaminase activity
LG951_11755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LG951_11760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LG951_11765	COG1480	7TM receptor with intracellular HD hydrolase
LG951_11770	COG1702	phosphate starvation-inducible protein PhoH
LG951_11775	COG0561	phosphatase activity
LG951_11795	COG4864	UPF0365 protein
LG951_11800	COG1030	water channel activity
LG951_11805	COG1610	YqeY-like protein
LG951_11815	COG1283	sodium-dependent phosphate transmembrane transporter activity
LG951_11820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LG951_11825	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LG951_11830	COG2264	protein methyltransferase activity
LG951_11835	COG0484	heat shock protein binding
LG951_11840	COG0443	Heat shock 70 kDa protein
LG951_11845	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LG951_11850	COG1420	regulation of RNA biosynthetic process
LG951_11855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LG951_11860	COG0481	GTPase activity
LG951_11870	COG0860	N-Acetylmuramoyl-L-alanine amidase
LG951_11875	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LG951_11880	COG0268	Binds directly to 16S ribosomal RNA
LG951_11885	COG1466	dna polymerase III delta subunit
LG951_11895	COG0658	competence protein
LG951_11895	COG2333	competence protein COMEC
LG951_11900	COG2131	deaminase
LG951_11905	COG1555	photosystem II stabilization
LG951_11910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LG951_11915	COG2226	methyltransferase
LG951_11920	COG0799	negative regulation of ribosome biogenesis
LG951_11925	COG1713	HD superfamily hydrolase involved in NAD metabolism
LG951_11930	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LG951_11935	COG1534	Rna-binding protein
LG951_11940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LG951_11945	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LG951_11950	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LG951_11965	COG2755	lipolytic protein G-D-S-L family
LG951_11975	COG0457	Tetratricopeptide repeat
LG951_11990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LG951_12000	COG0457	Tetratricopeptide repeat
LG951_12035	COG3409	Peptidoglycan-binding domain 1 protein
LG951_12035	COG5632	N-Acetylmuramoyl-L-alanine amidase
LG951_12070	COG3778	Protein conserved in bacteria
LG951_12075	COG3299	homolog of phage Mu protein gp47
LG951_12080	COG3628	GPW Gp25 family protein
LG951_12090	COG4193	domain, Protein
LG951_12095	COG1652	LysM domain
LG951_12100	COG3953	SLT domain
LG951_12100	COG5280	Phage tail tape measure protein TP901
LG951_12100	COG5280	Phage tail tape measure protein TP901
LG951_12100	COG3953	SLT domain
LG951_12160	COG4653	Phage capsid family
LG951_12165	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LG951_12185	COG2369	cell adhesion
LG951_12190	COG5518	Phage portal protein
LG951_12195	COG1783	phage Terminase large subunit
LG951_12235	COG5444	nuclease activity
LG951_12270	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
LG951_12280	COG0305	Participates in initiation and elongation during chromosome replication
LG951_12340	COG1396	sequence-specific DNA binding
LG951_12345	COG2856	Zn peptidase
LG951_12380	COG0726	polysaccharide deacetylase
LG951_12420	COG2160	L-arabinose isomerase activity
LG951_12435	COG1609	Transcriptional regulator
LG951_12445	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LG951_12450	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LG951_12455	COG1733	regulation of RNA biosynthetic process
LG951_12460	COG0657	acetylesterase activity
LG951_12500	COG1309	transcriptional regulator
LG951_12505	COG0109	protoheme IX farnesyltransferase activity
LG951_12510	COG2602	Beta-lactamase
LG951_12515	COG1960	acyl-CoA dehydrogenase activity
LG951_12520	COG1126	abc transporter atp-binding protein
LG951_12525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG951_12530	COG0765	amino acid transport
LG951_12540	COG1063	alcohol dehydrogenase
LG951_12550	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_12560	COG1115	amino acid carrier protein
LG951_12565	COG0583	DNA-binding transcription factor activity
LG951_12570	COG1063	alcohol dehydrogenase
LG951_12575	COG2226	methyltransferase
LG951_12600	COG0626	cystathionine gamma-synthase activity
LG951_12605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LG951_12610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LG951_12615	COG2226	methyltransferase
LG951_12630	COG0768	penicillin binding
LG951_12635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LG951_12675	COG0572	uridine kinase
LG951_12680	COG0826	peptidase U32
LG951_12685	COG0826	peptidase U32
LG951_12690	COG4122	O-methyltransferase activity
LG951_12695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LG951_12700	COG0183	Belongs to the thiolase family
LG951_12705	COG0318	PFAM AMP-dependent synthetase and ligase
LG951_12710	COG1268	BioY protein
LG951_12715	COG3906	Belongs to the UPF0473 family
LG951_12720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LG951_12725	COG4472	Bacterial protein of unknown function (DUF965)
LG951_12730	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LG951_12735	COG0628	permease
LG951_12740	COG1126	abc transporter atp-binding protein
LG951_12745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG951_12750	COG0765	amino acid transport
LG951_12755	COG0765	amino acid transport
LG951_12770	COG3881	PFAM PRC-barrel domain
LG951_12775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LG951_12780	COG0457	Tetratricopeptide repeat
LG951_12785	COG0482	sulfurtransferase activity
LG951_12790	COG1104	cysteine desulfurase activity
LG951_12795	COG1959	2 iron, 2 sulfur cluster binding
LG951_12800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LG951_12805	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LG951_12820	COG0124	histidyl-tRNA synthetase
LG951_12830	COG4991	sh3 domain protein
LG951_12830	COG3103	Sh3 type 3 domain protein
LG951_12830	COG0860	N-Acetylmuramoyl-L-alanine amidase
LG951_12835	COG1490	D-aminoacyl-tRNA deacylase activity
LG951_12840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LG951_12845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LG951_12850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LG951_12850	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LG951_12855	COG5416	Lipopolysaccharide assembly protein A domain
LG951_12860	COG0490	domain, Protein
LG951_12865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LG951_12865	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LG951_12875	COG2244	polysaccharide biosynthetic process
LG951_12880	COG2323	membrane
LG951_12890	COG1862	Preprotein translocase
LG951_12895	COG0343	queuine tRNA-ribosyltransferase activity
LG951_12900	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LG951_12910	COG2255	four-way junction helicase activity
LG951_12915	COG0632	four-way junction helicase activity
LG951_12925	COG2112	serine threonine protein kinase
LG951_12940	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LG951_12955	COG1388	LysM domain
LG951_12960	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LG951_12965	COG0157	Belongs to the NadC ModD family
LG951_12970	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LG951_12975	COG1104	cysteine desulfurase activity
LG951_12980	COG1827	regulation of RNA biosynthetic process
LG951_12985	COG0077	Prephenate dehydratase
LG951_12990	COG4492	Belongs to the UPF0735 family
LG951_12995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LG951_13000	COG3290	protein histidine kinase activity
LG951_13005	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LG951_13010	COG2868	ribosomal protein
LG951_13015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LG951_13020	COG1994	Peptidase M50
LG951_13025	COG0739	heme binding
LG951_13030	COG2894	cell division
LG951_13035	COG0850	regulation of cytokinetic process
LG951_13040	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LG951_13050	COG1077	Cell shape determining protein MreB Mrl
LG951_13055	COG2003	Belongs to the UPF0758 family
LG951_13060	COG0424	maF-like protein
LG951_13070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LG951_13075	COG0285	dihydrofolate synthase activity
LG951_13080	COG0525	valine-tRNA ligase activity
LG951_13090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LG951_13095	COG1388	LysM domain
LG951_13100	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LG951_13105	COG0113	porphobilinogen synthase activity
LG951_13110	COG1587	Uroporphyrinogen-III synthase
LG951_13115	COG0181	hydroxymethylbilane synthase activity
LG951_13120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LG951_13125	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LG951_13135	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LG951_13140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LG951_13145	COG0470	DNA polymerase III
LG951_13145	COG1067	ATP-dependent peptidase activity
LG951_13150	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LG951_13155	COG0544	peptidyl-prolyl cis-trans isomerase activity
LG951_13160	COG0457	Tetratricopeptide repeat
LG951_13160	COG1477	protein flavinylation
LG951_13165	COG0066	3-isopropylmalate dehydratase activity
LG951_13170	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LG951_13175	COG0473	3-isopropylmalate dehydrogenase activity
LG951_13180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LG951_13185	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LG951_13190	COG0440	acetolactate synthase activity
LG951_13195	COG0028	Belongs to the TPP enzyme family
LG951_13200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LG951_13205	COG2706	6-phosphogluconolactonase activity
LG951_13210	COG3339	Conserved Protein
LG951_13215	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LG951_13220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LG951_13225	COG1696	Membrane protein involved in D-alanine export
LG951_13230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG951_13305	COG0622	Phosphoesterase
LG951_13310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LG951_13315	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LG951_13320	COG5401	PFAM Sporulation and spore germination
LG951_13325	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LG951_13330	COG1846	Transcriptional regulator
LG951_13335	COG2197	response regulator
LG951_13340	COG2851	Citrate transporter
LG951_13345	COG0583	DNA-binding transcription factor activity
LG951_13350	COG2828	Protein conserved in bacteria
LG951_13360	COG0824	Thioesterase
LG951_13365	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LG951_13370	COG1053	succinate dehydrogenase
LG951_13375	COG2009	succinate dehydrogenase
LG951_13380	COG1719	4-vinyl reductase, 4VR
LG951_13385	COG0527	aspartate kinase activity
LG951_13390	COG0322	excinuclease ABC activity
LG951_13395	COG3118	belongs to the thioredoxin family
LG951_13400	COG3534	alpha-L-arabinofuranosidase
LG951_13405	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LG951_13410	COG2086	electron transfer activity
LG951_13415	COG1024	Enoyl-CoA hydratase
LG951_13420	COG1309	transcriptional regulator
LG951_13425	COG0318	PFAM AMP-dependent synthetase and ligase
LG951_13435	COG3766	membrane
LG951_13440	COG1193	negative regulation of DNA recombination
LG951_13445	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LG951_13445	COG1796	DNA polymerase
LG951_13450	COG1286	toxin biosynthetic process
LG951_13455	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LG951_13460	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LG951_13465	COG0072	phenylalanine-tRNA ligase activity
LG951_13465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG951_13470	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LG951_13475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LG951_13485	COG1966	Carbon starvation protein
LG951_13490	COG1363	Peptidase, m42
LG951_13500	COG3326	Membrane
LG951_13505	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LG951_13510	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LG951_13515	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LG951_13520	COG1346	cytolysis
LG951_13525	COG1380	Effector of murein hydrolase LrgA
LG951_13530	COG3279	Response regulator of the LytR AlgR family
LG951_13535	COG3275	phosphorelay sensor kinase activity
LG951_13540	COG1011	Hydrolase
LG951_13550	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LG951_13560	COG0398	Pfam SNARE associated Golgi protein
LG951_13565	COG1484	DNA-dependent DNA replication
LG951_13570	COG3611	Membrane attachment protein
LG951_13575	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LG951_13585	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LG951_13590	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LG951_13595	COG0237	dephospho-CoA kinase activity
LG951_13600	COG1971	Probably functions as a manganese efflux pump
LG951_13605	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LG951_13610	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LG951_13610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LG951_13615	COG5002	protein histidine kinase activity
LG951_13620	COG0745	RESPONSE REGULATOR receiver
LG951_13625	COG0039	L-malate dehydrogenase activity
LG951_13630	COG0538	isocitrate dehydrogenase activity
LG951_13635	COG0372	Belongs to the citrate synthase family
LG951_13640	COG2707	UPF0756 membrane protein
LG951_13645	COG0628	permease
LG951_13650	COG3030	protein affecting phage T7 exclusion by the F plasmid
LG951_13660	COG0205	6-phosphofructokinase activity
LG951_13665	COG0825	malonyl-CoA metabolic process
LG951_13670	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LG951_13675	COG0281	malic enzyme
LG951_13680	COG0587	DNA-directed DNA polymerase activity
LG951_13700	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LG951_13710	COG4109	DRTGG domain
LG951_13715	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LG951_13720	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_13730	COG0165	Argininosuccinate lyase
LG951_13735	COG0137	argininosuccinate synthase activity
LG951_13740	COG0521	Mo-molybdopterin cofactor biosynthetic process
LG951_13745	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LG951_13750	COG0827	DNA restriction-modification system
LG951_13755	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LG951_13760	COG3874	Sporulation protein YtfJ
LG951_13770	COG1714	RDD family
LG951_13775	COG0616	signal peptide processing
LG951_13780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LG951_13790	COG3239	Fatty acid desaturase
LG951_13795	COG4585	Histidine kinase
LG951_13800	COG2197	response regulator
LG951_13805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG951_13810	COG0745	RESPONSE REGULATOR receiver
LG951_13815	COG2205	protein histidine kinase activity
LG951_13820	COG0772	Belongs to the SEDS family
LG951_13825	COG1695	Transcriptional regulator
LG951_13830	COG1136	(ABC) transporter
LG951_13835	COG0577	efflux transmembrane transporter activity
LG951_13840	COG0402	S-adenosylhomocysteine deaminase activity
LG951_13845	COG2249	NAD(P)H dehydrogenase (quinone) activity
LG951_13855	COG1279	arginine transmembrane transporter activity
LG951_13860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LG951_13870	COG0301	tRNA thio-modification
LG951_13875	COG1104	cysteine desulfurase activity
LG951_13880	COG1114	Component of the transport system for branched-chain amino acids
LG951_13885	COG1114	Component of the transport system for branched-chain amino acids
LG951_13890	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LG951_13895	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LG951_13900	COG1309	transcriptional regulator
LG951_13905	COG1956	GAF domain-containing protein
LG951_13910	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LG951_13920	COG1335	isochorismatase
LG951_13925	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LG951_13930	COG2329	Antibiotic biosynthesis monooxygenase
LG951_13935	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LG951_13940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LG951_13945	COG0454	-acetyltransferase
LG951_13950	COG0517	IMP dehydrogenase activity
LG951_13955	COG0123	including yeast histone deacetylase and acetoin utilization protein
LG951_13960	COG1609	Transcriptional regulator
LG951_13965	COG1605	Chorismate mutase
LG951_13965	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LG951_13970	COG3118	belongs to the thioredoxin family
LG951_13975	COG4980	gas vesicle protein
LG951_13980	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LG951_13985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LG951_13990	COG1674	ftsk spoiiie
LG951_13995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG951_14000	COG4848	Belongs to the UPF0354 family
LG951_14005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG951_14020	COG1363	Peptidase, m42
LG951_14025	COG5584	Small secreted protein
LG951_14030	COG0281	malic enzyme
LG951_14035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG951_14040	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LG951_14050	COG0510	thiamine kinase activity
LG951_14055	COG1597	lipid kinase activity
LG951_14065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LG951_14070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LG951_14075	COG3340	Belongs to the peptidase S51 family
LG951_14080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LG951_14085	COG2252	PERMEase
LG951_14090	COG1349	DNA-binding transcription factor activity
LG951_14095	COG1187	pseudouridine synthase activity
LG951_14100	COG2244	polysaccharide biosynthetic process
LG951_14105	COG2081	HI0933 family
LG951_14115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LG951_14120	COG3196	Protein conserved in bacteria
LG951_14130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LG951_14135	COG5578	integral membrane protein
LG951_14140	COG0673	inositol 2-dehydrogenase activity
LG951_14145	COG1653	transport
LG951_14150	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LG951_14155	COG4209	transmembrane transport
LG951_14160	COG2207	Transcriptional regulator
LG951_14165	COG1733	regulation of RNA biosynthetic process
LG951_14170	COG2814	Major facilitator Superfamily
LG951_14175	COG0656	L-ascorbic acid biosynthetic process
LG951_14180	COG1653	transport
LG951_14185	COG0395	ABC-type sugar transport system, permease component
LG951_14190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LG951_14195	COG1073	alpha beta
LG951_14200	COG0495	leucyl-tRNA aminoacylation
LG951_14210	COG1366	Belongs to the anti-sigma-factor antagonist family
LG951_14210	COG2202	Pas domain
LG951_14215	COG2433	Pfam Transposase IS66
LG951_14220	COG0577	efflux transmembrane transporter activity
LG951_14225	COG1136	(ABC) transporter
LG951_14235	COG1131	(ABC) transporter
LG951_14240	COG1725	Transcriptional regulator
LG951_14255	COG1242	4 iron, 4 sulfur cluster binding
LG951_14260	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LG951_14270	COG2267	carboxylic ester hydrolase activity
LG951_14275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LG951_14280	COG0367	asparagine synthase
LG951_14285	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LG951_14290	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LG951_14300	COG1506	peptidase
LG951_14305	COG1233	COG1233 Phytoene dehydrogenase and related
LG951_14325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LG951_14330	COG1116	anion transmembrane transporter activity
LG951_14335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LG951_14340	COG0494	nUDIX hydrolase
LG951_14345	COG2310	stress, protein
LG951_14360	COG4824	toxin secretion phage lysis holin
LG951_14370	COG0783	Belongs to the Dps family
LG951_14385	COG1854	S-ribosylhomocysteine lyase activity
LG951_14390	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LG951_14395	COG0288	reversible hydration of carbon dioxide
LG951_14400	COG0803	Belongs to the bacterial solute-binding protein 9 family
LG951_14400	COG3443	Belongs to the bacterial solute-binding protein 9 family
LG951_14410	COG1271	oxidase subunit
LG951_14415	COG1294	oxidase, subunit
LG951_14430	COG4948	Mandelate Racemase Muconate Lactonizing
LG951_14435	COG0318	PFAM AMP-dependent synthetase and ligase
LG951_14440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LG951_14445	COG0596	Alpha beta hydrolase
LG951_14450	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LG951_14455	COG1169	isochorismate synthase
LG951_14460	COG1575	Belongs to the MenA family. Type 1 subfamily
LG951_14465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LG951_14595	COG3859	Proton-coupled thiamine transporter YuaJ
LG951_14600	COG1247	-acetyltransferase
LG951_14605	COG3339	Conserved Protein
LG951_14610	COG0772	Belongs to the SEDS family
LG951_14615	COG0772	Belongs to the SEDS family
LG951_14620	COG2268	Band 7 protein
LG951_14625	COG1585	Membrane protein implicated in regulation of membrane protease activity
LG951_14630	COG2318	DinB family
LG951_14635	COG1454	alcohol dehydrogenase
LG951_14640	COG1012	belongs to the aldehyde dehydrogenase family
LG951_14645	COG1510	regulation of RNA biosynthetic process
LG951_14675	COG3409	Peptidoglycan-binding domain 1 protein
LG951_14675	COG5632	N-Acetylmuramoyl-L-alanine amidase
LG951_14710	COG3778	Protein conserved in bacteria
LG951_14715	COG3299	homolog of phage Mu protein gp47
LG951_14720	COG3628	GPW Gp25 family protein
LG951_14730	COG4193	domain, Protein
LG951_14735	COG1652	LysM domain
LG951_14740	COG3953	SLT domain
LG951_14740	COG5280	Phage tail tape measure protein TP901
LG951_14740	COG3953	SLT domain
LG951_14740	COG5280	Phage tail tape measure protein TP901
LG951_14800	COG4653	Phage capsid family
LG951_14805	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LG951_14815	COG2369	cell adhesion
LG951_14820	COG5518	Phage portal protein
LG951_14825	COG1783	phage Terminase large subunit
LG951_14950	COG0305	Participates in initiation and elongation during chromosome replication
LG951_15030	COG0582	viral genome integration into host DNA
LG951_15045	COG5632	N-Acetylmuramoyl-L-alanine amidase
LG951_15045	COG3409	Peptidoglycan-binding domain 1 protein
LG951_15105	COG3778	Protein conserved in bacteria
LG951_15110	COG3299	homolog of phage Mu protein gp47
LG951_15115	COG3628	GPW Gp25 family protein
LG951_15125	COG4193	domain, Protein
LG951_15130	COG1652	LysM domain
LG951_15135	COG3953	SLT domain
LG951_15135	COG5280	Phage tail tape measure protein TP901
LG951_15135	COG3953	SLT domain
LG951_15135	COG5280	Phage tail tape measure protein TP901
LG951_15190	COG4653	Phage capsid family
LG951_15195	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LG951_15200	COG5518	Phage portal protein
LG951_15205	COG1783	phage Terminase large subunit
LG951_15210	COG5484	DNA packaging
LG951_15215	COG1595	DNA-templated transcription, initiation
LG951_15225	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
LG951_15245	COG1396	sequence-specific DNA binding
LG951_15255	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LG951_15270	COG0628	permease
LG951_15280	COG0673	inositol 2-dehydrogenase activity
LG951_15285	COG0693	protein deglycase activity
LG951_15290	COG0840	transmembrane signaling receptor activity
LG951_15295	COG0840	transmembrane signaling receptor activity
LG951_15300	COG0840	transmembrane signaling receptor activity
LG951_15305	COG0840	transmembrane signaling receptor activity
LG951_15320	COG2070	2-Nitropropane dioxygenase
LG951_15325	COG0432	Pfam Uncharacterised protein family UPF0047
LG951_15330	COG1253	flavin adenine dinucleotide binding
LG951_15335	COG2738	Putative neutral zinc metallopeptidase
LG951_15345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LG951_15360	COG0166	Belongs to the GPI family
LG951_15365	COG1979	alcohol dehydrogenase
LG951_15370	COG1979	alcohol dehydrogenase
LG951_15375	COG2155	Conserved Protein
LG951_15380	COG1098	S1 RNA binding domain
LG951_15385	COG0436	Aminotransferase
LG951_15390	COG1522	sequence-specific DNA binding
LG951_15395	COG2267	carboxylic ester hydrolase activity
LG951_15405	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LG951_15410	COG2205	protein histidine kinase activity
LG951_15425	COG5018	Exonuclease
LG951_15430	COG2814	Major facilitator Superfamily
LG951_15435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LG951_15440	COG3011	Protein conserved in bacteria
LG951_15450	COG3290	protein histidine kinase activity
LG951_15455	COG4565	transcriptional regulatory protein
LG951_15460	COG1744	ABC transporter substrate-binding protein PnrA-like
LG951_15465	COG3845	ABC transporter
LG951_15470	COG4603	Belongs to the binding-protein-dependent transport system permease family
LG951_15475	COG1079	Belongs to the binding-protein-dependent transport system permease family
LG951_15480	COG3493	citrate carrier protein
LG951_15490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LG951_15490	COG2111	Na H antiporter
LG951_15495	COG2111	Na H antiporter
LG951_15500	COG1006	Multisubunit Na H antiporter MnhC subunit
LG951_15505	COG0651	ATP synthesis coupled electron transport
LG951_15510	COG1863	multisubunit Na H antiporter MnhE subunit
LG951_15515	COG2212	antiporter activity
LG951_15520	COG1320	monovalent cation:proton antiporter activity
LG951_15525	COG2050	protein possibly involved in aromatic compounds catabolism
LG951_15530	COG2197	response regulator
LG951_15535	COG4585	Histidine kinase
LG951_15545	COG0142	geranyltranstransferase activity
LG951_15560	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LG951_15565	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LG951_15570	COG1335	isochorismatase
LG951_15575	COG5506	Protein of unknown function (DUF1694)
LG951_15595	COG0628	permease
LG951_15610	COG1418	mRNA catabolic process
LG951_15615	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_15625	COG1511	domain protein
LG951_15630	COG0433	COG0433 Predicted ATPase
LG951_15630	COG1674	ftsk spoiiie
LG951_15635	COG4499	WXG100 protein secretion system (Wss), protein YukC
LG951_15640	COG5417	Belongs to the EsaB family
LG951_15645	COG4842	Belongs to the WXG100 family
LG951_15650	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LG951_15650	COG2508	Transcriptional regulator
LG951_15655	COG0686	Belongs to the AlaDH PNT family
LG951_15660	COG1268	BioY protein
LG951_15665	COG4326	sporulation control protein
LG951_15670	COG2056	Na+-H+ antiporter family
LG951_15675	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LG951_15680	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LG951_15685	COG3584	3D domain protein
LG951_15700	COG1252	NADH dehydrogenase
LG951_15705	COG0492	ferredoxin-NADP+ reductase activity
LG951_15720	COG0316	Belongs to the HesB IscA family
LG951_15725	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LG951_15730	COG4844	belongs to the
LG951_15735	COG1252	NADH dehydrogenase
LG951_15745	COG4837	Protein of unknown function (DUF1462)
LG951_15755	COG0823	Involved in the tonB-independent uptake of proteins
LG951_15755	COG1506	peptidase
LG951_15755	COG4946	Tricorn protease homolog
LG951_15760	COG0083	homoserine kinase activity
LG951_15765	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LG951_15770	COG0460	homoserine dehydrogenase
LG951_15775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LG951_15780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LG951_15785	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LG951_15790	COG0647	UMP catabolic process
LG951_15795	COG2445	Protein of unknown function DUF86
LG951_15800	COG4470	Protein conserved in bacteria
LG951_15810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LG951_15815	COG0739	heme binding
LG951_15830	COG3377	Domain of unknown function (DUF1805)
LG951_15835	COG0737	Belongs to the 5'-nucleotidase family
LG951_15840	COG1801	Protein of unknown function DUF72
LG951_15845	COG2508	Transcriptional regulator
LG951_15850	COG2140	Oxalate decarboxylase
LG951_15855	COG2814	Major facilitator Superfamily
LG951_15860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LG951_15865	COG2356	endonuclease I
LG951_15880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG951_15885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG951_15890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG951_15920	COG5002	protein histidine kinase activity
LG951_15920	COG0642	Histidine kinase
LG951_15925	COG0745	RESPONSE REGULATOR receiver
LG951_15930	COG2311	Membrane
LG951_15940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LG951_15945	COG0719	Fe-S assembly protein
LG951_15950	COG0822	iron-sulfur transferase activity
LG951_15955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LG951_15960	COG0719	Fe-S assembly protein
LG951_15965	COG0396	ATPase activity
LG951_15975	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LG951_15980	COG1464	Belongs to the NlpA lipoprotein family
LG951_15985	COG2011	ABC-type metal ion transport system permease component
LG951_15990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LG951_16000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG951_16005	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LG951_16015	COG0509	glycine decarboxylation via glycine cleavage system
LG951_16020	COG1393	Belongs to the ArsC family
LG951_16025	COG1960	acyl-CoA dehydrogenase activity
LG951_16030	COG0183	Belongs to the thiolase family
LG951_16035	COG1250	3-hydroxyacyl-CoA dehydrogenase
LG951_16035	COG1024	Enoyl-CoA hydratase
LG951_16050	COG5577	PFAM Coat F domain
LG951_16060	COG1120	ATPase activity
LG951_16070	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_16075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG951_16080	COG0745	RESPONSE REGULATOR receiver
LG951_16085	COG2770	Histidine kinase
LG951_16085	COG2205	protein histidine kinase activity
LG951_16095	COG1309	transcriptional regulator
LG951_16100	COG0114	fumarate hydratase activity
LG951_16110	COG0697	spore germination
LG951_16115	COG0814	amino acid
LG951_16130	COG2197	response regulator
LG951_16135	COG4585	Histidine kinase
LG951_16140	COG4758	membrane
LG951_16150	COG1842	Phage shock protein A
LG951_16155	COG4758	membrane
LG951_16160	COG2096	Adenosyltransferase
LG951_16165	COG1120	ATPase activity
LG951_16170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG951_16175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG951_16185	COG2721	sulfolactate sulfo-lyase activity
LG951_16190	COG0246	Mannitol dehydrogenase
LG951_16195	COG1609	Transcriptional regulator
LG951_16200	COG1904	glucuronate isomerase
LG951_16205	COG2205	protein histidine kinase activity
LG951_16210	COG0745	RESPONSE REGULATOR receiver
LG951_16215	COG1120	ATPase activity
LG951_16220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG951_16225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG951_16230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG951_16235	COG0531	amino acid
LG951_16250	COG1988	membrane-bound metal-dependent
LG951_16255	COG1368	sulfuric ester hydrolase activity
LG951_16260	COG0725	ABC transporter, periplasmic molybdate-binding protein
LG951_16265	COG4149	molybdate abc transporter
LG951_16270	COG0656	L-ascorbic acid biosynthetic process
LG951_16275	COG1940	carbohydrate kinase activity
LG951_16280	COG0025	NhaP-type Na H and K H
LG951_16285	COG2860	membrane
LG951_16290	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LG951_16295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LG951_16300	COG2217	Heavy metal translocating P-type atpase
LG951_16305	COG1121	(ABC) transporter
LG951_16310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LG951_16315	COG0803	Belongs to the bacterial solute-binding protein 9 family
LG951_16325	COG3226	Transcriptional regulator
LG951_16330	COG0784	Response regulator, receiver
LG951_16335	COG4191	Histidine kinase
LG951_16340	COG1027	Aspartate ammonia-lyase
LG951_16350	COG2217	Heavy metal translocating P-type atpase
LG951_16355	COG2608	mercury ion transmembrane transporter activity
LG951_16360	COG1937	Protein conserved in bacteria
LG951_16390	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LG951_16395	COG0557	exoribonuclease II activity
LG951_16400	COG1647	Serine aminopeptidase, S33
LG951_16405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LG951_16410	COG2002	toxin-antitoxin pair type II binding
LG951_16415	COG1476	TRANSCRIPTIONal
LG951_16420	COG1396	sequence-specific DNA binding
LG951_16425	COG1396	sequence-specific DNA binding
LG951_16430	COG1733	regulation of RNA biosynthetic process
LG951_16435	COG1174	glycine betaine transport
LG951_16440	COG1732	Glycine betaine
LG951_16445	COG1174	glycine betaine transport
LG951_16450	COG1125	glycine betaine transport
LG951_16450	COG0517	IMP dehydrogenase activity
LG951_16455	COG1510	regulation of RNA biosynthetic process
LG951_16460	COG2095	MarC family integral membrane protein
LG951_16470	COG0456	acetyltransferase
LG951_16490	COG1122	ATPase activity
LG951_16500	COG0148	phosphopyruvate hydratase activity
LG951_16505	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LG951_16510	COG0149	triose-phosphate isomerase activity
LG951_16515	COG0126	phosphoglycerate kinase activity
LG951_16520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LG951_16525	COG2390	Transcriptional regulator
LG951_16530	COG0833	amino acid
LG951_16535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LG951_16540	COG3829	transcription factor binding
LG951_16545	COG2186	Transcriptional regulator
LG951_16550	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LG951_16560	COG0534	Mate efflux family protein
LG951_16565	COG4608	Belongs to the ABC transporter superfamily
LG951_16570	COG0444	Belongs to the ABC transporter superfamily
LG951_16575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LG951_16580	COG0601	transmembrane transport
LG951_16585	COG0747	negative chemotaxis
LG951_16590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LG951_16595	COG0110	maltose O-acetyltransferase activity
LG951_16600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LG951_16605	COG2244	polysaccharide biosynthetic process
LG951_16610	COG5039	Polysaccharide pyruvyl transferase
LG951_16615	COG1216	Glycosyl transferase, family 2
LG951_16625	COG0438	transferase activity, transferring glycosyl groups
LG951_16630	COG1215	transferase activity, transferring glycosyl groups
LG951_16635	COG0438	transferase activity, transferring glycosyl groups
LG951_16640	COG1086	Polysaccharide biosynthesis protein
LG951_16645	COG0489	protein tyrosine kinase activity
LG951_16650	COG3944	biosynthesis protein
LG951_16655	COG1396	sequence-specific DNA binding
LG951_16665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG951_16670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG951_16675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG951_16680	COG0726	polysaccharide deacetylase
LG951_16685	COG0488	(ABC) transporter
LG951_16690	COG1819	glycosyl
LG951_16710	COG0740	serine-type endopeptidase activity
LG951_16715	COG1611	Belongs to the LOG family
LG951_16720	COG1694	Mazg nucleotide pyrophosphohydrolase
LG951_16725	COG0659	secondary active sulfate transmembrane transporter activity
LG951_16730	COG0288	reversible hydration of carbon dioxide
LG951_16735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LG951_16745	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LG951_16750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG951_16755	COG1481	regulation of sporulation
LG951_16760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LG951_16765	COG1660	Displays ATPase and GTPase activities
LG951_16770	COG1051	belongs to the nudix hydrolase family
LG951_16775	COG0492	ferredoxin-NADP+ reductase activity
LG951_16780	COG3883	PFAM NLP P60 protein
LG951_16780	COG0791	NLP P60 protein
LG951_16785	COG0457	Tetratricopeptide repeat
LG951_16790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LG951_16790	COG0140	phosphoribosyl-ATP diphosphatase activity
LG951_16795	COG0107	imidazoleglycerol-phosphate synthase activity
LG951_16800	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LG951_16805	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LG951_16810	COG0131	Imidazoleglycerol-phosphate dehydratase
LG951_16815	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LG951_16820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LG951_16825	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LG951_16830	COG4990	cell redox homeostasis
LG951_16835	COG2910	NAD(P)H-binding
LG951_16840	COG1959	2 iron, 2 sulfur cluster binding
LG951_16845	COG0110	maltose O-acetyltransferase activity
LG951_16850	COG0546	phosphoglycolate phosphatase activity
LG951_16855	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LG951_16860	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LG951_16865	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LG951_16870	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LG951_16875	COG0363	glucosamine-6-phosphate deaminase activity
LG951_16880	COG2188	Transcriptional regulator
LG951_16885	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LG951_16890	COG1950	PFAM Membrane protein of
LG951_16895	COG1983	PspC domain protein
LG951_16900	COG3595	metallopeptidase activity
LG951_16915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LG951_16925	COG4897	Protein conserved in bacteria
LG951_16930	COG3848	Pyruvate phosphate dikinase
LG951_16930	COG0574	Belongs to the PEP-utilizing enzyme family
LG951_16935	COG1309	transcriptional regulator
LG951_16940	COG2814	Major facilitator Superfamily
LG951_16950	COG0745	RESPONSE REGULATOR receiver
LG951_16955	COG5002	protein histidine kinase activity
LG951_16960	COG1113	amino acid transport
LG951_16965	COG0778	Nitroreductase
LG951_16970	COG1733	regulation of RNA biosynthetic process
LG951_16975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG951_16985	COG0793	Belongs to the peptidase S41A family
LG951_16985	COG3409	Peptidoglycan-binding domain 1 protein
LG951_16990	COG0730	response to heat
LG951_16995	COG0791	NLP P60 protein
LG951_16995	COG3883	PFAM NLP P60 protein
LG951_17000	COG2177	Part of the ABC transporter FtsEX involved in
LG951_17005	COG2884	Cell division ATP-binding protein ftsE
LG951_17010	COG2010	Cytochrome c
LG951_17015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LG951_17035	COG0653	protein targeting
LG951_17040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LG951_17045	COG0840	transmembrane signaling receptor activity
LG951_17060	COG1516	flagellar protein fliS
LG951_17065	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LG951_17070	COG1334	flagellar protein FlaG
LG951_17075	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LG951_17080	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LG951_17090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LG951_17095	COG1256	bacterial-type flagellum assembly
LG951_17095	COG4786	Flagellar basal body rod
LG951_17100	COG3418	PFAM FlgN family protein
LG951_17115	COG1040	competence protein
LG951_17125	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LG951_17130	COG1307	EDD domain protein, DegV family
LG951_17135	COG2197	response regulator
LG951_17140	COG4585	Histidine kinase
LG951_17145	COG1739	Uncharacterized protein family UPF0029
LG951_17150	COG1316	TRANSCRIPTIONal
LG951_17155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LG951_17160	COG0438	transferase activity, transferring glycosyl groups
LG951_17165	COG1215	transferase activity, transferring glycosyl groups
LG951_17170	COG3206	protein involved in exopolysaccharide biosynthesis
LG951_17175	COG3307	-O-antigen
LG951_17180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LG951_17185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LG951_17190	COG0297	glycogen (starch) synthase activity
LG951_17190	COG0438	transferase activity, transferring glycosyl groups
LG951_17195	COG2244	polysaccharide biosynthetic process
LG951_17210	COG0860	N-Acetylmuramoyl-L-alanine amidase
LG951_17210	COG2247	cell wall binding repeat
LG951_17215	COG2385	sporulation resulting in formation of a cellular spore
LG951_17215	COG2247	cell wall binding repeat
LG951_17225	COG1316	TRANSCRIPTIONal
LG951_17230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LG951_17235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LG951_17240	COG1134	teichoic acid transport
LG951_17245	COG1682	transport, permease protein
LG951_17255	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LG951_17265	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LG951_17270	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LG951_17275	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LG951_17280	COG4193	domain, Protein
LG951_17285	COG1482	cell wall glycoprotein biosynthetic process
LG951_17295	COG1175	transmembrane transport
LG951_17300	COG1653	transport
LG951_17305	COG2197	response regulator
LG951_17310	COG2972	Histidine kinase
LG951_17320	COG0454	-acetyltransferase
LG951_17325	COG0800	Aldolase
LG951_17330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LG951_17335	COG1609	Transcriptional regulator
LG951_17340	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LG951_17345	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_17350	COG0697	spore germination
LG951_17355	COG0814	amino acid
LG951_17370	COG2814	Major facilitator Superfamily
LG951_17375	COG1316	TRANSCRIPTIONal
LG951_17380	COG0561	phosphatase activity
LG951_17385	COG0791	NLP P60 protein
LG951_17395	COG2843	Capsule synthesis protein
LG951_17405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LG951_17410	COG0697	spore germination
LG951_17425	COG1609	Transcriptional regulator
LG951_17430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LG951_17435	COG1869	D-ribose catabolic process
LG951_17440	COG1129	ABC transporter
LG951_17445	COG1172	Belongs to the binding-protein-dependent transport system permease family
LG951_17450	COG1879	ABC-type sugar transport system periplasmic component
LG951_17455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LG951_17460	COG0583	DNA-binding transcription factor activity
LG951_17465	COG0028	Belongs to the TPP enzyme family
LG951_17470	COG3527	Alpha-acetolactate decarboxylase
LG951_17475	COG1522	sequence-specific DNA binding
LG951_17480	COG2059	Chromate
LG951_17485	COG2059	Chromate
LG951_17490	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LG951_17500	COG4715	Zinc finger, swim domain protein
LG951_17505	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LG951_17510	COG1366	Belongs to the anti-sigma-factor antagonist family
LG951_17510	COG2202	Pas domain
LG951_17515	COG0561	phosphatase activity
LG951_17530	COG1970	mechanosensitive ion channel activity
LG951_17535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LG951_17540	COG0457	Tetratricopeptide repeat
LG951_17545	COG4786	Flagellar basal body rod
LG951_17550	COG4786	Flagellar basal body rod
LG951_17555	COG1077	Cell shape determining protein MreB Mrl
LG951_17560	COG1609	Transcriptional regulator
LG951_17565	COG1846	Transcriptional regulator
LG951_17570	COG2814	Major facilitator Superfamily
LG951_17575	COG0671	phosphoesterase, PA-phosphatase related
LG951_17580	COG0477	Major facilitator Superfamily
LG951_17585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG951_17590	COG0765	amino acid transport
LG951_17595	COG1126	abc transporter atp-binding protein
LG951_17600	COG0004	ammonium transporteR
LG951_17605	COG0347	Belongs to the P(II) protein family
LG951_17610	COG0739	heme binding
LG951_17615	COG1247	-acetyltransferase
LG951_17655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LG951_17660	COG0523	cobalamin synthesis protein
LG951_17665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LG951_17670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LG951_17675	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LG951_17680	COG2223	nitrite transmembrane transporter activity
LG951_17685	COG0243	molybdopterin cofactor binding
LG951_17690	COG2304	oxidoreductase activity
LG951_17695	COG2304	oxidoreductase activity
LG951_17700	COG2385	sporulation resulting in formation of a cellular spore
LG951_17705	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LG951_17715	COG4836	Membrane
LG951_17725	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LG951_17730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LG951_17735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LG951_17740	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LG951_17745	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LG951_17750	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LG951_17755	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LG951_17760	COG0356	it plays a direct role in the translocation of protons across the membrane
LG951_17770	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LG951_17775	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LG951_17780	COG4475	Protein of unknown function (DUF436)
LG951_17785	COG0698	ribose 5-phosphate isomerase
LG951_17790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LG951_17795	COG1971	Probably functions as a manganese efflux pump
LG951_17800	COG0009	L-threonylcarbamoyladenylate synthase
LG951_17805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LG951_17820	COG2890	protein-(glutamine-N5) methyltransferase activity
LG951_17825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LG951_17830	COG0789	Transcriptional regulator
LG951_17835	COG0679	Auxin Efflux Carrier
LG951_17840	COG0281	malic enzyme
LG951_17845	COG1435	thymidine kinase activity
LG951_17850	COG0254	rRNA binding
LG951_17855	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LG951_17860	COG1494	fructose-1,6-bisphosphatase
LG951_17865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LG951_17870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LG951_17875	COG0191	fructose-bisphosphate aldolase activity
LG951_17880	COG2204	response regulator
LG951_17885	COG4821	SIS domain
LG951_17890	COG0504	CTP synthase activity
LG951_17895	COG3343	RNA polymerase activity
LG951_17905	COG1960	acyl-CoA dehydrogenase activity
LG951_17910	COG1960	acyl-CoA dehydrogenase activity
LG951_17915	COG1250	3-hydroxyacyl-CoA dehydrogenase
LG951_17920	COG0183	Belongs to the thiolase family
LG951_17925	COG2181	nitrate reductase activity
LG951_17925	COG0247	lactate metabolic process
LG951_17930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LG951_17935	COG4294	response to UV
LG951_17945	COG1619	proteins homologs of microcin C7 resistance protein MccF
LG951_17950	COG1132	(ABC) transporter
LG951_17955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LG951_17960	COG1619	proteins homologs of microcin C7 resistance protein MccF
LG951_17965	COG0018	arginyl-trna synthetase
LG951_17970	COG4506	Protein conserved in bacteria
LG951_17980	COG0010	Belongs to the arginase family
LG951_17985	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LG951_17990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LG951_18000	COG1994	Peptidase M50
LG951_18005	COG1942	4-Oxalocrotonate Tautomerase
LG951_18015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG951_18020	COG0583	DNA-binding transcription factor activity
LG951_18025	COG0431	NADPH-dependent FMN reductase
LG951_18030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG951_18035	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LG951_18040	COG0454	-acetyltransferase
LG951_18045	COG0765	amino acid transport
LG951_18060	COG1126	abc transporter atp-binding protein
LG951_18065	COG3465	dGTPase activity
LG951_18070	COG1078	dGTPase activity
LG951_18075	COG4844	belongs to the
LG951_18120	COG5444	nuclease activity
LG951_18160	COG0280	phosphate acetyltransferase
LG951_18195	COG1396	sequence-specific DNA binding
LG951_18210	COG4191	Histidine kinase
LG951_18215	COG1073	alpha beta
LG951_18225	COG1522	sequence-specific DNA binding
LG951_18230	COG2814	Major facilitator Superfamily
LG951_18235	COG0077	Prephenate dehydratase
LG951_18240	COG1917	Cupin 2, conserved barrel domain protein
LG951_18245	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_18250	COG0151	Belongs to the GarS family
LG951_18255	COG0436	Aminotransferase
LG951_18260	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_18265	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LG951_18270	COG1091	dTDP-4-dehydrorhamnose reductase activity
LG951_18275	COG1088	dTDP-glucose 4,6-dehydratase activity
LG951_18280	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LG951_18285	COG3980	spore coat polysaccharide biosynthesis protein
LG951_18290	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
LG951_18295	COG2089	acid synthase
LG951_18300	COG0456	acetyltransferase
LG951_18305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LG951_18310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LG951_18315	COG0463	Glycosyl transferase, family 2
LG951_18335	COG2363	Small membrane protein
LG951_18340	COG2233	PERMEase
LG951_18350	COG1012	belongs to the aldehyde dehydrogenase family
LG951_18355	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LG951_18360	COG1216	Glycosyl transferase, family 2
LG951_18370	COG0351	phosphomethylpyrimidine kinase
LG951_18385	COG0457	Tetratricopeptide repeat
LG951_18415	COG1621	beta-fructofuranosidase activity
LG951_18420	COG1263	PTS System
LG951_18420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG951_18425	COG3711	transcriptional antiterminator
LG951_18435	COG1404	Belongs to the peptidase S8 family
LG951_18445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG951_18450	COG0778	Nitroreductase
LG951_18455	COG0772	Belongs to the SEDS family
LG951_18465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LG951_18470	COG1845	cytochrome c oxidase, subunit III
LG951_18475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LG951_18480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LG951_18490	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LG951_18495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LG951_18500	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LG951_18515	COG2246	polysaccharide biosynthetic process
LG951_18535	COG3162	membrane
LG951_18540	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LG951_18550	COG0352	thiamine-phosphate diphosphorylase activity
LG951_18555	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LG951_18560	COG0583	DNA-binding transcription factor activity
LG951_18565	COG1380	Effector of murein hydrolase LrgA
LG951_18570	COG1346	cytolysis
LG951_18575	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LG951_18580	COG0346	lactoylglutathione lyase activity
LG951_18590	COG0765	amino acid transport
LG951_18595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG951_18600	COG0457	Tetratricopeptide repeat
LG951_18610	COG2357	RelA SpoT domain protein
LG951_18615	COG1172	Belongs to the binding-protein-dependent transport system permease family
LG951_18620	COG1129	ABC transporter
LG951_18630	COG3420	alginic acid biosynthetic process
LG951_18635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LG951_18645	COG1486	melibiose metabolic process
LG951_18650	COG1447	Phosphotransferase system cellobiose-specific component IIA
LG951_18655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LG951_18660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LG951_18665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG951_18665	COG3711	transcriptional antiterminator
LG951_18685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LG951_18700	COG1595	DNA-templated transcription, initiation
LG951_18710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LG951_18715	COG4988	ABC transporter
LG951_18720	COG1294	oxidase, subunit
LG951_18725	COG1271	oxidase subunit
LG951_18750	COG4509	Sortase family
LG951_18775	COG5386	Cell surface protein
LG951_18780	COG5386	Cell surface protein
LG951_18785	COG1733	regulation of RNA biosynthetic process
LG951_18790	COG2514	catechol 2,3-dioxygenase activity
LG951_18795	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LG951_18795	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LG951_18800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LG951_18800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LG951_18810	COG0726	polysaccharide deacetylase
LG951_18815	COG1447	Phosphotransferase system cellobiose-specific component IIA
LG951_18820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LG951_18825	COG2723	6-phospho-beta-galactosidase activity
LG951_18830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LG951_18835	COG3711	transcriptional antiterminator
LG951_18835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG951_18860	COG1757	Na H antiporter
LG951_18865	COG1027	Aspartate ammonia-lyase
LG951_18870	COG0252	asparaginase activity
LG951_18875	COG1396	sequence-specific DNA binding
LG951_18900	COG4842	Belongs to the WXG100 family
LG951_18905	COG2195	Cleaves the N-terminal amino acid of tripeptides
LG951_18920	COG1737	Transcriptional regulator
LG951_18925	COG2084	Dehydrogenase
LG951_18935	COG2610	gluconate transmembrane transporter activity
LG951_18940	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LG951_18945	COG2723	6-phospho-beta-galactosidase activity
LG951_18950	COG2190	(PTS) system
LG951_18950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG951_18950	COG1263	PTS System
LG951_18955	COG3711	transcriptional antiterminator
LG951_18960	COG3878	Protein conserved in bacteria
LG951_18970	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LG951_18975	COG1122	ATPase activity
LG951_18980	COG4721	ABC-type cobalt transport system, permease component
LG951_18985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LG951_19020	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LG951_19025	COG0778	Nitroreductase
LG951_19030	COG1846	Transcriptional regulator
LG951_19035	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LG951_19040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LG951_19045	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LG951_19050	COG2390	Transcriptional regulator
LG951_19060	COG2755	lipolytic protein G-D-S-L family
LG951_19060	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LG951_19080	COG0561	phosphatase activity
LG951_19085	COG0789	Transcriptional regulator
LG951_19090	COG0673	inositol 2-dehydrogenase activity
LG951_19095	COG0840	transmembrane signaling receptor activity
LG951_19100	COG1113	amino acid transport
LG951_19105	COG4335	DNA alkylation repair
LG951_19115	COG1070	Carbohydrate kinase
LG951_19120	COG1737	Transcriptional regulator
LG951_19155	COG0583	DNA-binding transcription factor activity
LG951_19160	COG1609	Transcriptional regulator
LG951_19165	COG2182	Extracellular solute-binding protein
LG951_19170	COG1175	transmembrane transport
LG951_19175	COG3833	ABC-type maltose transport systems, permease component
LG951_19185	COG1874	Beta-galactosidase
LG951_19190	COG2851	Citrate transporter
LG951_19200	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LG951_19205	COG1131	(ABC) transporter
LG951_19210	COG2824	Alkylphosphonate utilization operon protein PhnA
LG951_19215	COG1929	Belongs to the glycerate kinase type-1 family
LG951_19220	COG2610	gluconate transmembrane transporter activity
LG951_19225	COG3835	regulator
LG951_19230	COG1309	transcriptional regulator
LG951_19235	COG2814	Major facilitator Superfamily
LG951_19245	COG1136	(ABC) transporter
LG951_19250	COG0457	Tetratricopeptide repeat
LG951_19255	COG3711	transcriptional antiterminator
LG951_19260	COG2723	6-phospho-beta-galactosidase activity
LG951_19265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG951_19265	COG1263	PTS System
LG951_19265	COG2190	(PTS) system
LG951_19300	COG1113	amino acid transport
LG951_19305	COG1609	Transcriptional regulator
LG951_19310	COG2814	Major facilitator Superfamily
LG951_19315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LG951_19320	COG2814	Major facilitator Superfamily
LG951_19355	COG2723	6-phospho-beta-galactosidase activity
LG951_19365	COG2188	Transcriptional regulator
LG951_19375	COG0384	phenazine biosynthesis protein PhzF
LG951_19380	COG0583	DNA-binding transcription factor activity
LG951_19415	COG2814	Major facilitator Superfamily
LG951_19420	COG0640	Transcriptional regulator
LG951_19445	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LG951_19455	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LG951_19465	COG4720	Psort location CytoplasmicMembrane, score
LG951_19485	COG0456	acetyltransferase
LG951_19490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG951_19495	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LG951_19500	COG4853	Protein conserved in bacteria
LG951_19505	COG4863	YycH protein
LG951_19510	COG5002	protein histidine kinase activity
LG951_19515	COG0745	RESPONSE REGULATOR receiver
LG951_19540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG951_19550	COG2311	Membrane
LG951_19555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LG951_19560	COG1309	transcriptional regulator
LG951_19565	COG2124	cytochrome p450
LG951_19570	COG0346	lactoylglutathione lyase activity
LG951_19575	COG0305	Participates in initiation and elongation during chromosome replication
LG951_19590	COG2819	hydrolase of the alpha beta superfamily
LG951_19595	COG1028	Short-chain dehydrogenase reductase Sdr
LG951_19600	COG1169	isochorismate synthase
LG951_19605	COG1021	2,3-dihydroxybenzoate-AMP ligase
LG951_19610	COG1535	isochorismatase
LG951_19610	COG3433	isochorismatase activity
LG951_19615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG951_19620	COG3251	PFAM MbtH domain protein
LG951_19625	COG2207	Transcriptional regulator
LG951_19625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG951_19630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG951_19635	COG2819	hydrolase of the alpha beta superfamily
LG951_19640	COG3093	addiction module antidote protein HigA
LG951_19645	COG2807	transmembrane transport
LG951_19650	COG0359	binds to the 23S rRNA
LG951_19655	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LG951_19660	COG4241	membrane
LG951_19665	COG1227	inorganic diphosphatase activity
LG951_19675	COG1595	DNA-templated transcription, initiation
LG951_19685	COG0753	catalase activity
LG951_19690	COG0655	NAD(P)H dehydrogenase (quinone) activity
LG951_19695	COG0400	carboxylic ester hydrolase activity
LG951_19700	COG0346	lactoylglutathione lyase activity
LG951_19705	COG1174	glycine betaine transport
LG951_19710	COG0517	IMP dehydrogenase activity
LG951_19710	COG1125	glycine betaine transport
LG951_19715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LG951_19720	COG0629	single-stranded DNA binding
LG951_19725	COG0360	Binds together with S18 to 16S ribosomal RNA
LG951_19730	COG0012	GTP binding
LG951_19735	COG4481	Protein conserved in bacteria
LG951_19750	COG3949	Membrane
LG951_19760	COG1475	DNA binding
LG951_19765	COG1192	Involved in chromosome partitioning
LG951_19775	COG1475	DNA binding
LG951_19780	COG0357	Ribosomal RNA small subunit methyltransferase G
LG951_19785	COG0445	tRNA wobble uridine modification
LG951_19790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LG951_19795	COG1847	R3H domain protein
LG951_19800	COG0706	membrane insertase activity
LG951_19805	COG0594	ribonuclease P activity
LG951_19810	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LG951_19845	COG0457	Tetratricopeptide repeat