locus-tag	class	description
BW16_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BW16_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BW16_00015	ENOG410848D	S4 domain protein YaaA
BW16_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BW16_00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BW16_00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BW16_00075	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BW16_00085	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BW16_00090	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
BW16_00095	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
BW16_00100	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BW16_00105	ENOG4105FKZ	Methyl-accepting chemotaxis
BW16_00115	ENOG4105ZMH	deoxynucleoside kinase
BW16_00125	ENOG4105VRS	hydrolase family 18
BW16_00130	ENOG4105GTG	Isochorismatase
BW16_00135	ENOG4108Z6B	deaminase
BW16_00140	ENOG4105C6E	dna polymerase iii
BW16_00145	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BW16_00150	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BW16_00160	ENOG41067KS	pro-sigma K processing
BW16_00200	ENOG4105CDW	Resistance protein
BW16_00205	ENOG4105CXN	decarboxylase
BW16_00210	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BW16_00215	ENOG4105X0R	protein from nitrogen regulatory protein P-II
BW16_00220	ENOG4105XVJ	Protein of unknown function (DUF327)
BW16_00225	ENOG4105FA2	dna polymerase iii
BW16_00230	ENOG4105MA4	psp1 domain protein
BW16_00235	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
BW16_00240	ENOG41060K3	Methyltransferase
BW16_00245	ENOG4105VC4	domain protein
BW16_00250	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
BW16_00255	ENOG4105KRN	Transcriptional regulator, abrb family
BW16_00260	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BW16_00265	ENOG4105F8V	Hydrolase, tatD family
BW16_00270	ENOG41069ER	domain protein
BW16_00280	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BW16_00285	ENOG4105XFA	sporulation peptidase YabG
BW16_00290	ENOG4105W42	Veg protein
BW16_00295	ENOG4105XEW	small acid-soluble spore protein
BW16_00300	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BW16_00305	ENOG4105DFT	pur operon repressor
BW16_00310	ENOG4105KME	endoribonuclease L-psp
BW16_00320	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BW16_00325	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BW16_00330	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BW16_00335	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BW16_00345	ENOG4108JA2	transcriptioN-repair coupling factor
BW16_00350	ENOG4108M14	stage v sporulation protein t
BW16_00365	ENOG41082I2	s4 domain protein
BW16_00370	ENOG4105VYY	sporulation protein yabp
BW16_00385	ENOG41060GV	RNA binding s1 domain protein
BW16_00415	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BW16_00420	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BW16_00425	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BW16_00430	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
BW16_00435	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BW16_00440	ENOG4107U48	ppic-type peptidyL-prolyl cis-trans isomerase
BW16_00445	ENOG4105C6T	cysteine synthase
BW16_00450	ENOG4105CRQ	synthase (Component I)
BW16_00455	ENOG4105DDQ	anthranilate synthase
BW16_00460	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
BW16_00465	ENOG4105EEI	dihydropteroate synthase
BW16_00470	ENOG4105KRF	dihydroneopterin aldolase
BW16_00475	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BW16_00485	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BW16_00490	ENOG4105CRK	lysyL-tRNA synthetase
BW16_00575	ENOG4108Z0C	Uvrb UvrC protein
BW16_00580	ENOG41066A3	ATP guanido phosphotransferase
BW16_00590	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BW16_00595	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
BW16_00600	ENOG4105CTP	PilT protein domain protein
BW16_00605	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BW16_00610	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BW16_00615	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BW16_00620	ENOG4105D7W	serine acetyltransferase
BW16_00625	ENOG4105C8N	cysteinyl-tRNA synthetase
BW16_00630	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BW16_00635	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BW16_00640	ENOG4105M0M	Tetracycline resistance protein
BW16_00655	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BW16_00660	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BW16_00665	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BW16_00670	ENOG4108VZM	50s ribosomal protein L10
BW16_00675	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BW16_00680	ENOG4107Y49	methyltransferase
BW16_00685	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BW16_00690	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BW16_00695	ENOG4105XPM	ribosomal protein
BW16_00700	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BW16_00705	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BW16_00710	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BW16_00720	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
BW16_00725	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BW16_00730	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BW16_00735	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BW16_00740	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BW16_00745	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BW16_00750	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BW16_00755	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BW16_00760	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BW16_00765	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BW16_00770	ENOG41082SA	50s ribosomal protein l29
BW16_00775	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BW16_00780	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BW16_00785	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BW16_00790	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BW16_00795	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BW16_00800	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BW16_00805	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BW16_00810	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BW16_00815	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BW16_00820	ENOG4105VPB	50S ribosomal protein L30
BW16_00825	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BW16_00830	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BW16_00835	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BW16_00840	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BW16_00845	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BW16_00855	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BW16_00860	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BW16_00865	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BW16_00870	ENOG4108ZT0	50S ribosomal protein l17
BW16_00875	ENOG4108JJB	ABC transporter
BW16_00880	ENOG4108JJB	ABC transporter
BW16_00885	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
BW16_00890	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BW16_00895	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BW16_00900	ENOG4108UJD	30S ribosomal protein S9
BW16_00935	ENOG4105D1F	ATP-binding protein
BW16_00950	ENOG4108NMV	polysaccharide deacetylase
BW16_00980	ENOG4105CHH	sulfate transporter
BW16_00990	ENOG4105EHZ	conserved protein UCP016719
BW16_00995	ENOG4105D17	glycoside hydrolase, family 3 domain protein
BW16_01015	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BW16_01050	ENOG4105EMN	RNA polymerase sigma factor
BW16_01060	ENOG4105C8B	TIGR00159 family
BW16_01065	ENOG4107U5W	ybbr family
BW16_01070	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BW16_01075	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BW16_01095	ENOG4105DA5	(ABC) transporter
BW16_01105	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BW16_01110	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BW16_01115	ENOG4105U3E	Transcriptional regulator
BW16_01125	ENOG4108WUZ	(ABC) transporter
BW16_01175	ENOG4105VZ8	Transcriptional regulator
BW16_01185	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
BW16_01195	ENOG4105YA8	Transcriptional regulator
BW16_01215	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
BW16_01220	ENOG4105CXY	transporter
BW16_01230	ENOG4105C7Z	Conserved Protein
BW16_01255	ENOG4105WAB	arsR family transcriptional regulator
BW16_01270	ENOG4105XTG	Pfam:DUF156
BW16_01275	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
BW16_01285	ENOG4105VFE	sira family
BW16_01290	ENOG4107TPS	domain protein
BW16_01295	ENOG4105VFE	sira family
BW16_01300	ENOG41087NI	Sulfite exporter TauE/SafE
BW16_01310	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
BW16_01320	ENOG4108SUT	Major Facilitator Superfamily
BW16_01345	ENOG4105EWC	Purine nucleoside phosphorylase
BW16_01360	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
BW16_01365	ENOG4105C72	UPF0176 protein
BW16_01370	ENOG4107QTZ	amino acid
BW16_01380	ENOG4105CID	antiterminator
BW16_01385	ENOG4105C5Y	PTS System
BW16_01390	ENOG4105CS2	ec 3.2.1.21
BW16_01410	ENOG4105DQ6	Transposase
BW16_01420	ENOG4105EMD	TRANSCRIPTIONal
BW16_01425	ENOG4105EVU	fructokinase
BW16_01430	ENOG4105C8I	hydrolase, family 38
BW16_01435	ENOG4105DM4	PTS System
BW16_01440	ENOG4108YRF	PTS System
BW16_01450	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BW16_01465	ENOG4108IQI	permease
BW16_01470	ENOG4108J5H	Homocysteine s-methyltransferase
BW16_01475	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
BW16_01495	ENOG4105C2C	drug resistance transporter, Bcr CflA
BW16_01520	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
BW16_01530	ENOG4105J7D	transcriptional regulator
BW16_01540	ENOG41067TZ	transcriptional regulator, MarR family
BW16_01550	ENOG4105CUB	amino acid
BW16_01560	ENOG4105D74	hydrolase
BW16_01570	ENOG4105CSV	Glutaminase
BW16_01585	ENOG41060AI	SEC-C motif
BW16_01595	ENOG4107SET	aldo keto reductase
BW16_01605	ENOG4107Y7X	LytTR
BW16_01610	ENOG4108IUW	ABC transporter
BW16_01615	ENOG4108SDH	ABC, transporter
BW16_01640	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
BW16_01650	ENOG4105DEN	Luciferase family
BW16_01655	ENOG4108N0M	stress protein
BW16_01660	ENOG4106FN3	tellurium resistance protein
BW16_01665	ENOG4106FN3	tellurium resistance protein
BW16_01670	ENOG4107TS3	membrane protein, TerC
BW16_01695	ENOG4108TTB	tellurium resistance protein
BW16_01705	ENOG4108IJ7	Glycine betaine
BW16_01710	ENOG4107SQ8	Glycine betaine
BW16_01740	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BW16_01760	ENOG4105TRI	Hydrolase
BW16_01805	ENOG4105EIG	urea carboxylase-associated protein 1
BW16_01810	ENOG4107RMH	nh(3)-dependent nad( ) synthetase
BW16_01825	ENOG4105FF2	Type I DHQase
BW16_01830	ENOG4105C7K	acetolactate synthase
BW16_01840	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
BW16_01845	ENOG4105DJB	Major Facilitator Superfamily
BW16_01855	ENOG4108N16	Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region
BW16_01860	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BW16_01865	ENOG41089UC	methyltransferase, type 11
BW16_01870	ENOG4105C5Q	Transcriptional regulator
BW16_01875	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
BW16_01880	ENOG4105I82	acetyl xylan esterase
BW16_01890	ENOG410756H	nucleotidyltransferase
BW16_01900	ENOG4105C26	Dehydrogenase
BW16_01905	ENOG4107YHD	transcriptional regulator
BW16_01910	ENOG4107R5R	arsenical pump membrane protein
BW16_01915	ENOG4105E5Q	amino acid AbC transporter
BW16_01920	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
BW16_01930	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
BW16_01940	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
BW16_01950	ENOG4105C8Q	Methyl-accepting chemotaxis
BW16_01980	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BW16_01985	ENOG4105F38	ABC transporter, permease
BW16_01995	ENOG4105CEY	Amp-dependent synthetase and ligase
BW16_02025	ENOG4105SX7	Transporter
BW16_02040	ENOG41086D8	Transcriptional regulator
BW16_02055	ENOG4105CDA	abc transporter atp-binding protein
BW16_02060	ENOG4105DRP	amino acid AbC transporter
BW16_02075	ENOG4108IQI	permease
BW16_02080	ENOG4105DUX	Transporter
BW16_02090	ENOG4105CPU	Monooxygenase
BW16_02095	ENOG4108XSB	acetyltransferase, (GNAT) family
BW16_02100	ENOG4105EAB	amino acid AbC transporter
BW16_02105	ENOG4108HW4	amino acid AbC transporter
BW16_02115	ENOG4105CH2	amidohydrolase
BW16_02120	ENOG4108PGP	mmge prpd family protein
BW16_02130	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BW16_02135	ENOG4105BZU	Histidine kinase
BW16_02145	ENOG4105CFH	Aspartokinase
BW16_02155	ENOG4105R8C	Transcriptional regulator
BW16_02160	ENOG4105YVS	arsR family transcriptional regulator
BW16_02170	ENOG4105EGI	Transcriptional regulator
BW16_02180	ENOG4108JPW	Aminotransferase
BW16_02185	ENOG4107QTZ	amino acid
BW16_02190	ENOG4105C26	Dehydrogenase
BW16_02195	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
BW16_02200	ENOG4105KTB	nuclear export factor GLE1
BW16_02205	ENOG4108T5E	Copper resistance protein
BW16_02220	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
BW16_02225	ENOG4105C8Q	Methyl-accepting chemotaxis
BW16_02265	ENOG4105X3H	Excalibur domain protein
BW16_02275	ENOG4105E7W	lamb ycsf family protein
BW16_02280	ENOG4105C5A	transporter
BW16_02285	ENOG4105CFM	UPF0317 protein
BW16_02290	ENOG4105P4J	Allophanate hydrolase, subunit 1
BW16_02300	ENOG4107258	Transcriptional regulator
BW16_02305	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
BW16_02315	ENOG4105XJB	lipolytic protein G-D-S-L family
BW16_02325	ENOG4105ETD	TRANSCRIPTIONal
BW16_02330	ENOG4105HMZ	Methyltransferase
BW16_02335	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BW16_02345	ENOG410606W	general stress protein
BW16_02370	ENOG4105VCH	membrane
BW16_02375	ENOG4105DRR	Transcriptional regulator, GntR family
BW16_02380	ENOG4106AXJ	AraC family transcriptional regulator
BW16_02385	ENOG410631K	Membrane
BW16_02390	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BW16_02395	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BW16_02410	ENOG4105I5R	Uncharacterized protein conserved in bacteria (DUF2334)
BW16_02415	ENOG4107R8N	Glycosyl transferase, family 2
BW16_02425	ENOG4105C0X	amino acid
BW16_02460	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
BW16_02465	ENOG4107BMA	Transglycosylase associated protein
BW16_02470	ENOG4105EU9	
BW16_02475	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
BW16_02480	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
BW16_02485	ENOG4108MRH	transcriptional regulatory protein
BW16_02490	ENOG4107QJT	sodium dicarboxylate symporter
BW16_02495	ENOG4106F5Q	Membrane
BW16_02505	ENOG4105CJ1	ABC, transporter
BW16_02525	ENOG4105SZ6	Thioredoxin
BW16_02530	ENOG4105CPF	Cell wall formation (By similarity)
BW16_02535	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
BW16_02550	ENOG4105C1J	atp-dependent rna helicase
BW16_02555	ENOG410905X	membrane-flanked domain protein
BW16_02560	ENOG4105CKV	Membrane
BW16_02575	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
BW16_02580	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BW16_02590	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
BW16_02595	ENOG4107MMM	Anti-sigma-factor antagonist
BW16_02600	ENOG4105FUA	antagonist
BW16_02605	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
BW16_02610	ENOG4107SGM	protein serine threonine phosphatase
BW16_02615	ENOG4105WN5	stage II sporulation protein
BW16_02620	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
BW16_02630	ENOG41064BQ	Phosphatase
BW16_02650	ENOG4107RUY	(E1 component), alpha subunit
BW16_02660	ENOG4107QKR	Dehydrogenase
BW16_02670	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
BW16_02710	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
BW16_02730	ENOG4105RHY	Pfam:UPF0157
BW16_02735	ENOG4105VEQ	Cold shock protein
BW16_02745	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BW16_02760	ENOG4105VUF	Transcriptional regulator
BW16_02770	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
BW16_02795	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BW16_02810	ENOG4107GJV	short-chain dehydrogenase reductase
BW16_02820	ENOG4107RB3	L-asparaginase
BW16_02825	ENOG4106HB6	Alpha beta hydrolase
BW16_02860	ENOG4105DQ6	Transposase
BW16_02895	ENOG4105VDT	-acetyltransferase
BW16_02900	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
BW16_02910	ENOG4105ST3	Transcriptional regulator
BW16_02915	ENOG4105NAE	bifunctional deaminase-reductase domain protein
BW16_02920	ENOG41090MY	MarR family Transcriptional regulator
BW16_02925	ENOG4108TVJ	Nitroreductase
BW16_02945	ENOG4108JCI	Transcriptional regulator
BW16_02950	ENOG4108VP3	Lysine exporter protein (LysE YggA)
BW16_02955	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
BW16_02965	ENOG4107ZBN	O-methyltransferase
BW16_02975	ENOG4108UMN	azlc family
BW16_03030	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
BW16_03035	ENOG4105K8N	protein family UPF0079, ATPase
BW16_03040	ENOG41072GX	Peptidase M22 Glycoprotease
BW16_03045	ENOG410801F	ribosomal-protein-alanine acetyltransferase
BW16_03050	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BW16_03055	ENOG4105C5H	ABC transporter
BW16_03060	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BW16_03065	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
BW16_03070	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
BW16_03075	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
BW16_03090	ENOG4108TYN	CAAX amino terminal protease family protein
BW16_03095	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BW16_03100	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BW16_03105	ENOG4108U05	Transcriptional regulator
BW16_03115	ENOG4108VXD	carboxy-peptidase
BW16_03155	ENOG4107STQ	Multicopper oxidase
BW16_03160	ENOG4105C85	amino acid
BW16_03170	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BW16_03185	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BW16_03190	ENOG4108UIN	ybak prolyl-trna synthetase associated region
BW16_03200	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BW16_03205	ENOG4108DMH	HTH_ARAC
BW16_03230	ENOG4105DY9	regulatoR
BW16_03235	ENOG4105KNA	-acetyltransferase
BW16_03250	ENOG4105JVQ	RNA Polymerase
BW16_03260	ENOG4108RWP	Major Facilitator Superfamily protein
BW16_03265	ENOG4105GZI	Transcriptional regulator
BW16_03270	ENOG4105C7N	Xanthine uracil vitamin C permease
BW16_03290	ENOG4108U5N	UPF0316 protein
BW16_03300	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BW16_03305	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
BW16_03310	ENOG4105C83	adenylosuccinate lyase
BW16_03315	ENOG4105C8V	SAICAR synthetase
BW16_03320	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
BW16_03330	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
BW16_03340	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BW16_03345	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
BW16_03350	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BW16_03355	ENOG4105C12	Phosphoribosylglycinamide synthetase
BW16_03375	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BW16_03390	ENOG4107S4Y	M20 DapE family protein YgeY
BW16_03405	ENOG4105KGF	protein, YerC YecD
BW16_03415	ENOG4105CBC	glutamate synthase
BW16_03430	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
BW16_03435	ENOG4105C4R	Atp-dependent dna helicase
BW16_03440	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BW16_03450	ENOG4105CRN	Aminoglycoside phosphotransferase
BW16_03455	ENOG4105KT7	mgtC SapB transporter
BW16_03460	ENOG4105CK7	Sodium proline symporter
BW16_03465	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BW16_03470	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BW16_03475	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BW16_03480	ENOG4108IG5	Transcriptional regulator
BW16_03490	ENOG4105DU0	nucleoside hydrolase
BW16_03495	ENOG4105CBD	Diacylglycerol kinase
BW16_03500	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BW16_03510	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BW16_03535	ENOG4105C3M	thioredoxin reductase
BW16_03550	ENOG4105F8D	glycoside hydrolase family 4
BW16_03555	ENOG4105HX0	Transcriptional regulator
BW16_03580	ENOG4108R1P	
BW16_03590	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
BW16_03600	ENOG41090R9	glycosyltransferase
BW16_03605	ENOG4107R51	Glycosyl transferase, family 2
BW16_03610	ENOG41090R9	glycosyltransferase
BW16_03615	ENOG4105EU0	Major facilitator Superfamily
BW16_03620	ENOG4107RVG	penicillin-binding protein
BW16_03625	ENOG4105C8P	)-transporter
BW16_03655	ENOG4105CUB	amino acid
BW16_03660	ENOG4107TVC	Glycosyl transferase, family 2
BW16_03665	ENOG4105C5H	ABC transporter
BW16_03670	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
BW16_03675	ENOG4107SWG	transcriptional regulator MERR family
BW16_03680	ENOG4105DXB	Major Facilitator superfamily
BW16_03685	ENOG4105C5H	ABC transporter
BW16_03690	ENOG4105FDU	atp-dependent rna helicase
BW16_03715	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
BW16_03740	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BW16_03745	ENOG4105E6M	Sulphatase-modifying factor protein
BW16_03755	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
BW16_03770	ENOG4108MRH	transcriptional regulatory protein
BW16_03790	ENOG4105PY6	Phenolic acid decarboxylase
BW16_03795	ENOG4105U3E	Transcriptional regulator
BW16_03810	ENOG41084AG	Acylphosphatase
BW16_03815	ENOG4108RPX	mosc domain containing protein
BW16_03830	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
BW16_03840	ENOG4105NX3	Membrane
BW16_03860	ENOG4105DY8	decarboxylase
BW16_03875	ENOG4105C5Y	PTS System
BW16_03880	ENOG4105CG3	alpha amylase, catalytic region
BW16_03885	ENOG4107414	GntR family transcriptional regulator
BW16_03895	ENOG4105CGH	5'-nucleotidase
BW16_03900	ENOG4107RKG	DJ-1/PfpI family
BW16_03910	ENOG4105BZG	amino acid carrier protein
BW16_03920	ENOG4105KJF	protein tyrosine phosphatase
BW16_03930	ENOG4107U9T	Pfam:Ribonuclease_BN
BW16_03940	ENOG4108ISG	Major Facilitator
BW16_03950	ENOG4105UPD	Calcium Proton
BW16_03960	ENOG4105CDY	transcriptional regulatory protein
BW16_03970	ENOG4105D8X	mechanosensitive ion channel
BW16_03995	ENOG4105D7N	magnesium and cobalt transport protein CorA
BW16_04010	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BW16_04075	ENOG4107TXC	Transcriptional regulator
BW16_04080	ENOG4108RWP	Major Facilitator Superfamily protein
BW16_04095	ENOG4105C22	threonyL-tRNA synthetase
BW16_04145	ENOG410839T	multidrug resistance protein
BW16_04165	ENOG4107TDE	lipolytic protein G-D-S-L family
BW16_04180	ENOG4108HUF	Transporter
BW16_04185	ENOG4105BZ1	(ABC) transporter
BW16_04190	ENOG4105KK4	UPF0060 membrane protein
BW16_04195	ENOG4105K6V	RNA polymerase
BW16_04220	ENOG4108YYS	metal-dependent hydrolase (By similarity)
BW16_04230	ENOG410834F	Transcriptional regulator
BW16_04255	ENOG4107Y03	Nitroreductase
BW16_04270	ENOG4105ECP	epimerase
BW16_04275	ENOG4105KC9	Modulates RecA activity (By similarity)
BW16_04300	ENOG4105CKK	Glycosyl transferase, family 2
BW16_04305	ENOG4105EJV	Membrane
BW16_04310	ENOG4105MSY	salicylate hydroxylase
BW16_04325	ENOG4105F0F	Oxalate decarboxylase
BW16_04335	ENOG4106DF4	Sigma-70, region 4
BW16_04345	ENOG41067AE	Membrane-bound metal-dependent hydrolase
BW16_04350	ENOG4105CEN	a g-specific adenine glycosylase
BW16_04355	ENOG4106BXE	
BW16_04360	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
BW16_04375	ENOG4105EVI	UPF0374 protein
BW16_04380	ENOG4105BZ1	(ABC) transporter
BW16_04385	ENOG4105C3U	ABC transporter
BW16_04390	ENOG4108JQ7	(ABC) transporter
BW16_04395	ENOG4105DEF	Extracellular solute-binding protein, family 5
BW16_04400	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BW16_04405	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BW16_04410	ENOG4107NBY	Membrane
BW16_04415	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BW16_04420	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BW16_04425	ENOG4105G5W	regulator Fur family
BW16_04580	ENOG4105E0M	Sulfatase
BW16_04610	ENOG4105CJ1	ABC, transporter
BW16_04645	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BW16_04655	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
BW16_04670	ENOG4105CYN	Serine protein kinase
BW16_04675	ENOG4106AKX	UPF0229 protein
BW16_04680	ENOG4105CW7	secretion protein, HlyD family
BW16_04685	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BW16_04690	ENOG4105CS1	NAD(P)H quinone oxidoreductase
BW16_04700	ENOG4105VEQ	Cold shock protein
BW16_04705	ENOG4105BZU	Histidine kinase
BW16_04735	ENOG4105BZU	Histidine kinase
BW16_04750	ENOG4108YBP	pseudouridine synthase
BW16_04765	ENOG4107YBY	Hydrolase
BW16_04770	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
BW16_04790	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
BW16_04795	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BW16_04800	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
BW16_04810	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BW16_04815	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BW16_04825	ENOG4105BZU	Histidine kinase
BW16_04830	ENOG4105WH1	Two component transcriptional regulator luxr family
BW16_04845	ENOG4105CH6	catalase
BW16_04850	ENOG4105KPV	Transcriptional regulator
BW16_04855	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
BW16_04860	ENOG4105ED1	spovr family
BW16_04865	ENOG4105G6Z	alkaline phosphatase
BW16_04875	ENOG4105CUB	amino acid
BW16_04885	ENOG4105J37	
BW16_04890	ENOG4108AEY	RNA polymerase sigma factor
BW16_04895	ENOG4105F6E	Acyl-transferase
BW16_04900	ENOG4105C37	(CBS) domain
BW16_04910	ENOG4105C37	(CBS) domain
BW16_04920	ENOG4106A8V	Protein CrcB homolog
BW16_04925	ENOG4105WMR	Protein CrcB homolog
BW16_04930	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BW16_04940	ENOG4105D64	Mechanosensitive ion channel
BW16_04945	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
BW16_04950	ENOG4107VMI	polysaccharide deacetylase
BW16_04955	ENOG4105F0I	Aminotransferase
BW16_04980	ENOG4105BZ1	(ABC) transporter
BW16_04985	ENOG4105BZ1	(ABC) transporter
BW16_05020	ENOG410839P	
BW16_05030	ENOG4108UH6	UPF0754 membrane protein
BW16_05035	ENOG4105WZB	UPF0342 protein
BW16_05045	ENOG4105D4P	Coproporphyrinogen iii oxidase
BW16_05055	ENOG4107S91	Sodium hydrogen exchanger
BW16_05060	ENOG4105NCW	Trka-c domain protein
BW16_05070	ENOG4105CGU	Enoyl-CoA hydratase
BW16_05080	ENOG4107VRP	DNA repair exonuclease
BW16_05085	ENOG4106D4I	domain protein
BW16_05100	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
BW16_05140	ENOG4105NBU	tryptophan transport protein
BW16_05145	ENOG4105DXJ	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BW16_05150	ENOG4105K59	histidine triad (HIT) protein
BW16_05185	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
BW16_05190	ENOG4105BZ4	penicillin-binding protein
BW16_05195	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
BW16_05200	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BW16_05205	ENOG4105C1Q	protoporphyrinogen oxidase
BW16_05215	ENOG4105ECB	domain protein
BW16_05220	ENOG4105DER	m42 family
BW16_05235	ENOG4108RQ5	Beta-lactamase domain-containing protein
BW16_05240	ENOG4105DF9	Lipoate-protein, ligase
BW16_05245	ENOG4105CEY	Amp-dependent synthetase and ligase
BW16_05255	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
BW16_05260	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BW16_05265	ENOG4107TB6	phosphoglycerate mutase
BW16_05270	ENOG4106YBV	Methyl-accepting chemotaxis
BW16_05290	ENOG4105XVF	Competence transcription factor
BW16_05295	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BW16_05300	ENOG410635T	phage-like element pbsx protein
BW16_05360	ENOG4108NF7	phage-type endonuclease
BW16_05365	ENOG4108PNI	recT protein
BW16_05380	ENOG4106CVF	DNA replication protein
BW16_05395	ENOG4105QBX	endodeoxyribonuclease RusA
BW16_05560	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
BW16_05590	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BW16_05600	ENOG4105XVF	Competence transcription factor
BW16_05615	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BW16_05620	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BW16_05625	ENOG41067XF	inhibitor
BW16_05630	ENOG4105DHS	permease protein
BW16_05635	ENOG4105CM4	permease protein
BW16_05640	ENOG4108IPW	abc transporter atp-binding protein
BW16_05650	ENOG4108KGH	TRANSCRIPTIONal
BW16_05660	ENOG41060YP	
BW16_05675	ENOG4108KK1	membrane protein AbrB duplication
BW16_05705	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
BW16_05715	ENOG4105EYH	Exonuclease
BW16_05775	ENOG4105ERH	Fumarylacetoacetate hydrolase
BW16_05780	ENOG4106BKT	UPF0344 protein
BW16_05790	ENOG4105CAQ	asparagine synthetase
BW16_05815	ENOG4105UQX	Mate efflux family protein
BW16_05820	ENOG4106HBX	Transcriptional Regulator AraC Family
BW16_05845	ENOG4105DY8	decarboxylase
BW16_05890	ENOG4108VPT	UPF0234 protein
BW16_05895	ENOG4105QNR	S1 RNA binding domain protein
BW16_05900	ENOG4105DIH	basic membrane
BW16_05905	ENOG4105C8Q	Methyl-accepting chemotaxis
BW16_05910	ENOG4105EPR	degv family
BW16_05915	ENOG4107AYK	membrAne
BW16_05925	ENOG41073B9	
BW16_05935	ENOG4108KP7	hydrolase
BW16_05940	ENOG4108MXZ	Esterase
BW16_05945	ENOG4105VG1	fes assembly suf system protein
BW16_05950	ENOG4105IQ5	FAD linked oxidase domain protein
BW16_05960	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
BW16_05970	ENOG4105CAS	nag kinase
BW16_05975	ENOG4105C8Y	Acetylornithine aminotransferase
BW16_05980	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BW16_05990	ENOG4105DBV	ornithine carbamoyltransferase
BW16_06025	ENOG4107RMD	Basic membrane lipoprotein
BW16_06040	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BW16_06045	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BW16_06055	ENOG4105C3U	ABC transporter
BW16_06060	ENOG4108JQ7	(ABC) transporter
BW16_06075	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BW16_06085	ENOG4105C31	Tryptophanyl-tRNA synthetase
BW16_06090	ENOG4108J59	Extracellular solute-binding protein, family 5
BW16_06095	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BW16_06100	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BW16_06110	ENOG4108JQ7	(ABC) transporter
BW16_06125	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
BW16_06130	ENOG4108ZCF	integral membrane protein
BW16_06135	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
BW16_06140	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BW16_06150	ENOG4105DPN	Oligoendopeptidase f
BW16_06160	ENOG4105T58	Dithiol-disulfide isomerase
BW16_06165	ENOG4108Z18	K06886 hemoglobin
BW16_06170	ENOG4105E4C	Lytic transglycosylase catalytic
BW16_06175	ENOG4105MIX	Adenylate cyclase
BW16_06180	ENOG4106EFP	UPF0738 protein
BW16_06190	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BW16_06195	ENOG4105EMS	pseudouridine synthase
BW16_06200	ENOG4107S1Q	Phosphatase
BW16_06210	ENOG4105ETU	transcriptional activator (TenA
BW16_06215	ENOG4108VEU	Thiamine monophosphate synthase
BW16_06230	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BW16_06235	ENOG4105D06	uba thif-type nad fad binding protein
BW16_06240	ENOG4105DWF	phosphomethylpyrimidine kinase
BW16_06245	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
BW16_06250	ENOG4107A88	
BW16_06305	ENOG4105ENA	helicase
BW16_06330	ENOG4105C28	cystathionine
BW16_06335	ENOG4105C28	cystathionine
BW16_06345	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
BW16_06360	ENOG4105I03	Flagellin
BW16_06365	ENOG4105DJ2	Major Facilitator Superfamily
BW16_06375	ENOG4107RSM	transcriptional regulator
BW16_06405	ENOG41082BV	acetyltransferase
BW16_06430	ENOG4105E1F	short-chain dehydrogenase reductase
BW16_06450	ENOG4105DUM	transcriptional regulator, lysR family
BW16_06470	ENOG4107V2S	Transcriptional regulator
BW16_06475	ENOG4105DJ2	Major Facilitator Superfamily
BW16_06525	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BW16_06535	ENOG4105PF9	Transcriptional regulator
BW16_06545	ENOG4105I03	Flagellin
BW16_06550	ENOG4105I03	Flagellin
BW16_06555	ENOG4105I03	Flagellin
BW16_06575	ENOG4105K7W	phage-related replication protein
BW16_06580	ENOG410635T	phage-like element pbsx protein
BW16_06605	ENOG4105CJ3	phosphate transporter
BW16_06610	ENOG4107GRR	phosphate transport regulator
BW16_06620	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BW16_06625	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
BW16_06630	ENOG4108I5D	sulfate abc transporter
BW16_06635	ENOG4105ECW	sulfate abc transporter
BW16_06640	ENOG4108IJ6	ABC transporter
BW16_06650	ENOG4105DT3	PTS system, galactitol-specific IIc component
BW16_06670	ENOG4107RUY	(E1 component), alpha subunit
BW16_06675	ENOG4105CPP	Dehydrogenase, E1 component
BW16_06680	ENOG4107QKR	Dehydrogenase
BW16_06690	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
BW16_06695	ENOG4105CHR	reductase
BW16_06700	ENOG4107RHR	regulatoR
BW16_06710	ENOG4107R7I	amino acid
BW16_06720	ENOG4105C0H	protease
BW16_06730	ENOG4108ME1	Peptidase M55 D-aminopeptidase
BW16_06735	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BW16_06740	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BW16_06745	ENOG4105C3U	ABC transporter
BW16_06760	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
BW16_06765	ENOG4105DTQ	mandelate racemase muconate lactonizing
BW16_06770	ENOG4107SN7	NLP P60 protein
BW16_06775	ENOG4108JQ7	(ABC) transporter
BW16_06780	ENOG4107TUM	Amidinotransferase
BW16_06785	ENOG4108S4H	thioesterase Superfamily protein
BW16_06790	ENOG4105K7K	Transcriptional regulator
BW16_06805	ENOG4108428	Inherit from COG: -acetyltransferase
BW16_06810	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BW16_06815	ENOG410839T	multidrug resistance protein
BW16_06820	ENOG41080TC	multidrug resistance protein
BW16_06830	ENOG4105CIY	formyltetrahydrofolate deformylase
BW16_06835	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
BW16_06840	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BW16_06860	ENOG4105K56	Transcriptional regulator
BW16_06865	ENOG4108ZHJ	Organic hydroperoxide resistance protein
BW16_06870	ENOG4107Y2X	deaminase
BW16_06875	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
BW16_06880	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BW16_06895	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BW16_06900	ENOG41062D9	Histidine kinase
BW16_06910	ENOG4106849	propeptide, pepSY amd peptidase M4
BW16_06930	ENOG4105CJW	magnesium transporter
BW16_06950	ENOG4105V75	Transcriptional regulator
BW16_06970	ENOG4105BZU	Histidine kinase
BW16_06975	ENOG4107T5V	SNARE associated Golgi
BW16_06980	ENOG4107TS3	membrane protein, TerC
BW16_06985	ENOG4108WZW	RNA polymerase sigma
BW16_06995	ENOG410681C	small acid-soluble spore protein
BW16_07005	ENOG4105D0M	Protease HtpX homolog
BW16_07015	ENOG410900G	Protein of unknown function (DUF421)
BW16_07030	ENOG4108TGC	Acyltransferase
BW16_07035	ENOG4105BZU	Histidine kinase
BW16_07040	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BW16_07050	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
BW16_07055	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
BW16_07065	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
BW16_07070	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
BW16_07075	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
BW16_07080	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
BW16_07090	ENOG4105BZU	Histidine kinase
BW16_07095	ENOG41090MY	MarR family Transcriptional regulator
BW16_07100	ENOG4105ER2	Ompa motb domain protein
BW16_07105	ENOG4105E14	MotA TolQ exbB proton channel
BW16_07120	ENOG4108K88	Membrane
BW16_07130	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BW16_07135	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
BW16_07140	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BW16_07145	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
BW16_07165	ENOG4105F0V	Cell wall hydrolase
BW16_07180	ENOG4105C59	p-type ATPase
BW16_07185	ENOG4105DC7	peptidase M24
BW16_07200	ENOG4105CID	antiterminator
BW16_07210	ENOG4105KRI	phosphocarrier protein (HPr
BW16_07215	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BW16_07225	ENOG4105F6S	Spore photoproduct lyase
BW16_07230	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
BW16_07235	ENOG4105CHR	reductase
BW16_07240	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BW16_07245	ENOG4105K4I	Scp-like extracellular
BW16_07255	ENOG4105BZU	Histidine kinase
BW16_07260	ENOG4105CHM	Aminotransferase
BW16_07275	ENOG41085PJ	rdd domain containing protein
BW16_07285	ENOG4107R88	Chemotaxis protein (CheV)
BW16_07290	ENOG4105UIN	
BW16_07295	ENOG4108MCI	Transcriptional regulator, ARAC family
BW16_07300	ENOG4108UZ3	Transporter
BW16_07320	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
BW16_07330	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
BW16_07335	ENOG4105EPM	Diguanylate phosphodiesterase
BW16_07340	ENOG4105WEF	catalase
BW16_07345	ENOG4107IN1	Protein of unknown function (DUF1797)
BW16_07350	ENOG4108XRC	Protein of unknown function (DUF458) 
BW16_07385	ENOG4105NQC	Flavodoxin
BW16_07390	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
BW16_07400	ENOG4106AUC	UPF0180 protein
BW16_07415	ENOG4105D8X	mechanosensitive ion channel
BW16_07420	ENOG4105D3R	alkyl hydroperoxide reductase
BW16_07425	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BW16_07440	ENOG41080QG	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
BW16_07445	ENOG4105D06	uba thif-type nad fad binding protein
BW16_07450	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BW16_07455	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
BW16_07460	ENOG4108ZAF	Molybdopterin
BW16_07465	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
BW16_07480	ENOG4107X8C	Efflux transporter RND family MFP subunit
BW16_07485	ENOG4105C19	ABC transporter
BW16_07490	ENOG4107RBB	ABC transporter, permease
BW16_07495	ENOG4105E98	transcriptional regulator DeoR family
BW16_07500	ENOG4105DE4	1-phosphofructokinase
BW16_07505	ENOG4105DM4	PTS System
BW16_07510	ENOG4105C3F	Signal peptidase i
BW16_07520	ENOG4105C5H	ABC transporter
BW16_07555	ENOG4105BZU	Histidine kinase
BW16_07565	ENOG4107ZYR	domain protein
BW16_07575	ENOG4105CPN	adenine deaminase
BW16_07580	ENOG4105CN5	Metallo-Beta-Lactamase
BW16_07590	ENOG4108X4Q	Hydrolase
BW16_07595	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BW16_07615	ENOG4105CPP	Dehydrogenase, E1 component
BW16_07620	ENOG4105C7S	Dehydrogenase
BW16_07625	ENOG4107QN2	dihydrolipoyl dehydrogenase
BW16_07640	ENOG4105CXN	decarboxylase
BW16_07650	ENOG4108WQ8	UPF0637 protein
BW16_07660	ENOG4105ECY	inositol monophosphatase
BW16_07695	ENOG4105CI3	gtp-binding protein typa
BW16_07700	ENOG4105QA2	
BW16_07715	ENOG4108IAB	Phoh family
BW16_07725	ENOG4105CSV	Glutaminase
BW16_07735	ENOG4105CNI	cell division protein FtsW
BW16_07740	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
BW16_07745	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BW16_07755	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
BW16_07765	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BW16_07770	ENOG4105CCU	oxidase (Subunit III)
BW16_07775	ENOG41064X9	cytochrome C oxidase subunit IV
BW16_07790	ENOG41080XQ	Signal transduction protein with cbs domains
BW16_07795	ENOG4106UY4	Inherit from COG: Scp-like extracellular
BW16_07820	ENOG4105WUC	UPF0298 protein
BW16_07825	ENOG4106H78	methyltransferase
BW16_07830	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BW16_07835	ENOG4105H20	Sporulation integral membrane protein YlbJ
BW16_07840	ENOG4105D78	K07001 NTE family protein
BW16_07845	ENOG41063PX	domain protein
BW16_07850	ENOG4105CDE	UPF0348 protein
BW16_07855	ENOG4105KNH	Nucleic acid-binding protein
BW16_07860	ENOG41067VY	50S ribosomal protein L32
BW16_07885	ENOG4108V6E	Cell division protein mraZ
BW16_07890	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BW16_07900	ENOG4105CJN	penicillin-binding protein
BW16_07905	ENOG4105CJN	penicillin-binding protein
BW16_07910	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BW16_07920	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BW16_07925	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BW16_07930	ENOG4105CNI	cell division protein FtsW
BW16_07935	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BW16_07940	ENOG4105D4A	Cell wall formation (By similarity)
BW16_07945	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
BW16_07950	ENOG4108R2U	division initiation protein
BW16_07960	ENOG4105K67	small basic protein
BW16_07965	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
BW16_07970	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BW16_07980	ENOG4105FFI	sigma-e processing peptidase spoiiga
BW16_07985	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BW16_07995	ENOG4105DKT	Transcriptional regulator
BW16_08010	ENOG410787A	Pts system, glucitol sorbitol-specific
BW16_08015	ENOG4105DZY	Pts system, glucitol sorbitol-specific
BW16_08020	ENOG4105VI0	Pts system, glucitol sorbitol-specific
BW16_08025	ENOG4105DKW	ABC transporter
BW16_08030	ENOG4105WR5	sporulation protein, YlmC YmxH family
BW16_08035	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
BW16_08040	ENOG4105DFA	alanine racemase domain protein
BW16_08045	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BW16_08050	ENOG41067XK	integral membrane protein
BW16_08055	ENOG4105DBK	s4 domain protein
BW16_08065	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BW16_08075	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BW16_08080	ENOG4105C34	Pseudouridine synthase
BW16_08090	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
BW16_08100	ENOG4105CXT	aspartate transcarbamylase
BW16_08105	ENOG4105CD3	dihydroorotase
BW16_08110	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BW16_08115	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BW16_08120	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
BW16_08125	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
BW16_08130	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
BW16_08135	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BW16_08145	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
BW16_08155	ENOG4107RIQ	Sulfate adenylate transferase
BW16_08160	ENOG4108WF4	Catalyzes the synthesis of activated sulfate (By similarity)
BW16_08165	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BW16_08170	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
BW16_08175	ENOG41087GM	Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein
BW16_08180	ENOG4105F23	Fibronectin-binding protein
BW16_08190	ENOG4105DSJ	YicC domain protein
BW16_08195	ENOG4105KC4	UPF0296 protein
BW16_08200	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BW16_08210	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
BW16_08215	ENOG4105C25	Primosomal protein n'
BW16_08220	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BW16_08225	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BW16_08230	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BW16_08235	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BW16_08240	ENOG4108ZF3	Phosphatase
BW16_08245	ENOG4105D9P	serine threonine protein kinase
BW16_08250	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BW16_08255	ENOG4105DJV	ribulose-phosphate 3-epimerase
BW16_08260	ENOG4105FJ0	thiamine
BW16_08270	ENOG4105VB9	50S ribosomal protein l28
BW16_08275	ENOG4108ZAA	Alkaline-shock protein
BW16_08280	ENOG4105DP4	dak2 domain fusion protein ylov
BW16_08290	ENOG4105EJQ	L-serine dehydratase
BW16_08295	ENOG4105CB5	ATP-dependent DNA helicase recG
BW16_08300	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
BW16_08305	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
BW16_08310	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BW16_08315	ENOG4105CHR	reductase
BW16_08320	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BW16_08325	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BW16_08330	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
BW16_08335	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BW16_08340	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
BW16_08350	ENOG4105K5M	30s ribosomal protein S16
BW16_08355	ENOG4108BW8	UPF0109 protein
BW16_08365	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BW16_08370	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BW16_08375	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BW16_08380	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
BW16_08385	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BW16_08395	ENOG4105VM1	flagellar
BW16_08400	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BW16_08405	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
BW16_08410	ENOG4105C79	DNA protecting protein DprA
BW16_08415	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BW16_08420	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
BW16_08425	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BW16_08430	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
BW16_08435	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
BW16_08445	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
BW16_08450	ENOG4108ZC9	flagellar basal-body rod protein flgc
BW16_08455	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
BW16_08460	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
BW16_08465	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BW16_08480	ENOG4106YF4	Flagellar biosynthesis chaperone
BW16_08490	ENOG410696Y	Flagellar hook-length control protein
BW16_08495	ENOG410822I	Flagellar hook capping protein
BW16_08500	ENOG4108JQA	flagellar
BW16_08505	ENOG41068WV	flagellar FlbD family protein
BW16_08515	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BW16_08520	ENOG4105DD5	Flagellar motor switch protein
BW16_08525	ENOG4107YTP	response regulator receiver protein
BW16_08535	ENOG4105CN7	Flagellar biosynthetic protein FliP
BW16_08540	ENOG4105VS8	Flagellar biosynthetic protein fliq
BW16_08545	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
BW16_08550	ENOG4105D00	flagellar biosynthetic protein flhB
BW16_08555	ENOG4105D7B	Flagellar biosynthesis protein flha
BW16_08560	ENOG4105FZW	flagellar biosynthesis regulator FlhF
BW16_08570	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BW16_08575	ENOG4105CBS	Chea signal transduction histidine kinase
BW16_08580	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
BW16_08590	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
BW16_08595	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BW16_08605	ENOG4105CE9	30S ribosomal protein S2
BW16_08610	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BW16_08620	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BW16_08625	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BW16_08630	ENOG4105KNE	Phosphatidate cytidylyltransferase
BW16_08635	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BW16_08640	ENOG4105DZP	Membrane-associated zinc metalloprotease
BW16_08645	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BW16_08660	ENOG4105CYP	glycoside hydrolase, family
BW16_08665	ENOG4105WJF	
BW16_08675	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
BW16_08680	ENOG4105CHV	Transcription elongation factor NusA
BW16_08685	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
BW16_08690	ENOG4105VHM	ribosomal protein
BW16_08695	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BW16_08700	ENOG4105W7A	Protein of unknown function (DUF503)
BW16_08705	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BW16_08710	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BW16_08715	ENOG4105DTN	riboflavin biosynthesis protein ribF
BW16_08720	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BW16_08725	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BW16_08735	ENOG4105C1V	Peptidase, M16
BW16_08750	ENOG4105E35	Dipicolinate synthase subunit A
BW16_08755	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
BW16_08760	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
BW16_08770	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BW16_08780	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
BW16_08790	ENOG4105CNU	cell division protein FtsK
BW16_08795	ENOG4105FDP	GntR family transcriptional regulator
BW16_08805	ENOG4105EYF	MMPL domain protein
BW16_08825	ENOG4105EYF	MMPL domain protein
BW16_08835	ENOG4105XZV	Protein of unknown function (DUF3243)
BW16_08850	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BW16_08855	ENOG4105CEV	competence damage-inducible protein
BW16_08860	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BW16_08865	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
BW16_08870	ENOG4105D48	metallophosphoesterase
BW16_08875	ENOG4105MCT	stage V sporulation protein S
BW16_08885	ENOG4105CPQ	Dehydrogenase
BW16_08890	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BW16_08900	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BW16_08915	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BW16_08920	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BW16_08945	ENOG4108VJ1	Transcriptional regulator (CarD family
BW16_08950	ENOG4105K7W	phage-related replication protein
BW16_08960	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BW16_08965	ENOG4105K7W	phage-related replication protein
BW16_08970	ENOG4108X3M	OsmC Ohr family protein
BW16_09000	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BW16_09020	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
BW16_09025	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BW16_09030	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BW16_09035	ENOG4105U6W	MutT NUDIX family protein
BW16_09045	ENOG4106F1P	AAA ATPase, central domain protein
BW16_09055	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BW16_09060	ENOG4105CXI	aluminum resistance protein
BW16_09065	ENOG4105KV4	Transcriptional regulator
BW16_09070	ENOG4105C5F	glutamine synthetase
BW16_09150	ENOG4108ZMX	Domain of unknown function (DU1801)
BW16_09170	ENOG410780I	phosphoprotein phosphatase activity
BW16_09185	ENOG4105XPP	Protein of unknown function (DUF1275)
BW16_09190	ENOG4105DQE	DNA ligase
BW16_09195	ENOG4105FDF	Could be involved in DNA repair (By similarity)
BW16_09200	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
BW16_09210	ENOG4108Z40	Transcriptional regulator
BW16_09215	ENOG4105ECR	NmrA family
BW16_09220	ENOG4107R5T	Cysteine-rich domain
BW16_09225	ENOG4107QR9	Iron-sulfur cluster binding protein
BW16_09230	ENOG41080R8	Conserved Protein
BW16_09250	ENOG4108QY0	Membrane
BW16_09255	ENOG41082JN	Transcriptional regulator
BW16_09260	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
BW16_09265	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
BW16_09270	ENOG4105EDW	glycosyl transferase, family 39
BW16_09275	ENOG4105WFK	nuclease
BW16_09280	ENOG4106SCS	STAS domain
BW16_09295	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BW16_09305	ENOG4108SVB	resolvase
BW16_09310	ENOG4105VPS	UPF0291 protein
BW16_09315	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BW16_09325	ENOG4105VXM	UPF0154 protein
BW16_09335	ENOG4107QIV	Cytochrome c biogenesis protein
BW16_09365	ENOG4108I0Z	Aconitate hydratase
BW16_09370	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BW16_09395	ENOG4105MI2	
BW16_09400	ENOG4105W8X	HesB YadR YfhF-family protein
BW16_09405	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
BW16_09410	ENOG4105K4P	CoA-binding domain protein
BW16_09415	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BW16_09435	ENOG4106UW1	Major Facilitator superfamily
BW16_09440	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BW16_09445	ENOG4108UW5	maltose o-acetyltransferase
BW16_09450	ENOG4108UXE	Protein tyrosine phosphatase
BW16_09455	ENOG4107R5R	arsenical pump membrane protein
BW16_09460	ENOG41082YX	Transcriptional regulator, arsr family
BW16_09475	ENOG4107ZXU	DSBA oxidoreductase
BW16_09480	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
BW16_09490	ENOG4105ST3	Transcriptional regulator
BW16_09495	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
BW16_09500	ENOG4105KVH	Transcriptional regulator
BW16_09510	ENOG4105C6T	cysteine synthase
BW16_09515	ENOG4105KME	endoribonuclease L-psp
BW16_09530	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
BW16_09560	ENOG4105CS2	ec 3.2.1.21
BW16_09565	ENOG4105C5Y	PTS System
BW16_09585	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BW16_09595	ENOG4107SYN	Glycosyl hydrolases family 43
BW16_09610	ENOG4105I1K	ABC transporter
BW16_09615	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
BW16_09635	ENOG4105UP7	3-epimerase
BW16_09650	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
BW16_09660	ENOG4105KD7	acetyltransferase
BW16_09665	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BW16_09710	ENOG4105DM4	PTS System
BW16_09715	ENOG4105DM4	PTS System
BW16_09720	ENOG4105DE4	1-phosphofructokinase
BW16_09725	ENOG4105HX0	Transcriptional regulator
BW16_09730	ENOG4107RZC	phospholipase d
BW16_09765	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
BW16_09775	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BW16_09780	ENOG4107QX3	carboxylase
BW16_09785	ENOG4105E39	Enoyl-CoA hydratase
BW16_09795	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
BW16_09800	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BW16_09805	ENOG4105CEY	Amp-dependent synthetase and ligase
BW16_09810	ENOG4105C1G	acyl-Coa dehydrogenase
BW16_09815	ENOG4105F32	YngK protein
BW16_09825	ENOG4105E98	transcriptional regulator DeoR family
BW16_09830	ENOG41090U3	tautomerase
BW16_09845	ENOG4105CQB	FAD linked oxidase domain protein
BW16_09850	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
BW16_09860	ENOG4108B31	Spore germination protein
BW16_09880	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BW16_09885	ENOG4107T5V	SNARE associated Golgi
BW16_09890	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
BW16_09900	ENOG4105DEN	Luciferase family
BW16_09915	ENOG4107QJQ	Mate efflux family protein
BW16_09920	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
BW16_09925	ENOG4105NBR	Pectinesterase
BW16_09930	ENOG4105H67	Protein of unknown function (DUF421)
BW16_09935	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
BW16_09940	ENOG4108IFG	nitrite reductase, (NAD(P)H)
BW16_09945	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
BW16_09960	ENOG4105BZ8	glutamate synthase
BW16_09965	ENOG4105CBC	glutamate synthase
BW16_09970	ENOG4105C5Q	Transcriptional regulator
BW16_09980	ENOG4105BZ1	(ABC) transporter
BW16_09985	ENOG41090E6	transcriptional regulator MERR family
BW16_09990	ENOG4108UYN	gCN5-related N-acetyltransferase
BW16_09995	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BW16_10000	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
BW16_10005	ENOG4105II7	pyrroline-5-carboxylate reductase
BW16_10015	ENOG4108J2R	molybdopterin oxidoreductase
BW16_10025	ENOG4105CMG	Carbohydrate kinase
BW16_10035	ENOG4105E2R	ROK family
BW16_10045	ENOG4105CT4	transporter
BW16_10050	ENOG4108Z7R	Chaperone CsaA
BW16_10060	ENOG4105FVX	
BW16_10085	ENOG4108W8B	Beta-lactamase domain protein
BW16_10095	ENOG4105D29	Helix-turn-helix type 11 domain protein
BW16_10110	ENOG4105KTU	Transcriptional regulator, arsr family
BW16_10115	ENOG4105CUB	amino acid
BW16_10125	ENOG4105CR4	methylisocitrate lyase
BW16_10130	ENOG4105DXD	2-methylcitrate dehydratase
BW16_10140	ENOG4108SJC	Membrane
BW16_10155	ENOG41069ER	domain protein
BW16_10160	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BW16_10165	ENOG4105SCY	DNAK suppressor
BW16_10190	ENOG4105C26	Dehydrogenase
BW16_10200	ENOG4105EWU	Squalene--hopene cyclase
BW16_10205	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BW16_10210	ENOG4105C09	Bile acid
BW16_10215	ENOG4105C7S	Dehydrogenase
BW16_10225	ENOG4107T89	von Willebrand factor, type A
BW16_10230	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
BW16_10240	ENOG4105K4H	Nlp p60 protein
BW16_10255	ENOG4107QMU	Mate efflux family protein
BW16_10275	ENOG4105FR1	rard protein
BW16_10305	ENOG4105E1V	na solute symporter
BW16_10325	ENOG4108VXD	carboxy-peptidase
BW16_10330	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
BW16_10335	ENOG4106Z5R	
BW16_10340	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BW16_10360	ENOG4105VSD	UPF0346 protein
BW16_10370	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
BW16_10375	ENOG4108JUB	Transcriptional regulator
BW16_10405	ENOG4105C5E	polysaccharide biosynthesis protein
BW16_10410	ENOG4105E0X	reductase
BW16_10415	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BW16_10440	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
BW16_10445	ENOG41090WU	lipolytic protein G-D-S-L family
BW16_10450	ENOG4108KF3	Electron transport protein SCO1 SenC
BW16_10465	ENOG4105C7B	Threonine dehydratase
BW16_10475	ENOG4108UT2	hemolysin iii
BW16_10485	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
BW16_10490	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BW16_10510	ENOG4107YX5	Pfam:DUF548
BW16_10515	ENOG4108Y6J	UPF0403 protein
BW16_10520	ENOG4105C01	Dihydroxy-acid dehydratase
BW16_10535	ENOG4108V06	Glutathione peroxidase
BW16_10540	ENOG4105CKU	formyltetrahydrofolate synthetase
BW16_10550	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
BW16_10585	ENOG41081VK	Ribonuclease
BW16_10610	ENOG410890F	Dynamin family
BW16_10620	ENOG41065KQ	synthase
BW16_10625	ENOG4107VMI	polysaccharide deacetylase
BW16_10630	ENOG4105C2W	permease
BW16_10640	ENOG4105CTD	carboxy-peptidase
BW16_10645	ENOG4105DVT	helicase
BW16_10655	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
BW16_10660	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
BW16_10665	ENOG4108UKS	UPF0398 protein
BW16_10675	ENOG4107X2U	Inherit from COG: Exonuclease-like protein
BW16_10680	ENOG4108I5C	dEAD DEAH box helicase
BW16_10685	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BW16_10725	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
BW16_10730	ENOG4105BZ4	penicillin-binding protein
BW16_10740	ENOG4105CSM	endonuclease III
BW16_10765	ENOG4105DVT	helicase
BW16_10770	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
BW16_10775	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
BW16_10780	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
BW16_10790	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BW16_10795	ENOG4105CPK	Glycosyl transferase (Group 1
BW16_10800	ENOG4105FJR	Lmbe family
BW16_10805	ENOG4108Z5K	methylglyoxal synthase
BW16_10810	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BW16_10815	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
BW16_10820	ENOG4108JYZ	YitT family
BW16_10840	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BW16_10855	ENOG4108SXZ	UPF0302 protein
BW16_10860	ENOG41068YB	TPR repeat-containing protein
BW16_10865	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BW16_10875	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BW16_10880	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BW16_10885	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BW16_10890	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
BW16_10895	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BW16_10900	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BW16_10910	ENOG4105KHN	chorismate mutase
BW16_10915	ENOG4105D49	3-dehydroquinate synthase
BW16_10920	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BW16_10925	ENOG4105BZU	Histidine kinase
BW16_10930	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BW16_10935	ENOG4105EAH	synthase
BW16_10940	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BW16_10945	ENOG4105XXQ	heptaprenyl diphosphate synthase component I
BW16_10955	ENOG4105EUJ	GTP cyclohydrolase i
BW16_10960	ENOG4105K70	DNA-binding protein
BW16_10965	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
BW16_10980	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BW16_10985	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BW16_10990	ENOG41065D1	
BW16_10995	ENOG4105S2F	
BW16_11015	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BW16_11020	ENOG4105CAT	Cytidine monophosphate kinase
BW16_11035	ENOG4105MSI	germination protein ypeb
BW16_11045	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
BW16_11050	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
BW16_11065	ENOG4107RGJ	metallophosphoesterase
BW16_11080	ENOG4105I7S	Abortive infection protein
BW16_11085	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BW16_11090	ENOG4105T7X	
BW16_11100	ENOG4108SAX	Membrane
BW16_11105	ENOG4108JQ1	Dehydrogenase
BW16_11125	ENOG4105BZU	Histidine kinase
BW16_11130	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BW16_11135	ENOG4105CRE	cytochrome C
BW16_11140	ENOG4107TWT	Cytochrome c biogenesis protein
BW16_11150	ENOG4105FE9	pseudouridine synthase
BW16_11160	ENOG4108JIC	nucleoside recognition domain protein
BW16_11165	ENOG4105DZ1	carboxypeptidase
BW16_11175	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BW16_11180	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
BW16_11210	ENOG4108R6K	riboflavin synthase, subunit alpha
BW16_11235	ENOG4107ZE5	PPIases accelerate the folding of proteins
BW16_11240	ENOG4105PTM	secreted protein
BW16_11245	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
BW16_11255	ENOG4105G6R	Stage v sporulation protein ae
BW16_11265	ENOG4105CZ3	stage V sporulation protein ad
BW16_11270	ENOG41090VF	Stage v sporulation protein ac
BW16_11285	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BW16_11290	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
BW16_11295	ENOG41082AN	stage II sporulation protein
BW16_11300	ENOG4105DZ1	carboxypeptidase
BW16_11305	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
BW16_11310	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
BW16_11315	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BW16_11325	ENOG4105I3K	Ferric uptake regulator, Fur family
BW16_11330	ENOG4105MZ9	stage II sporulation protein m
BW16_11345	ENOG4107YB6	acetyltransferase, (GNAT) family
BW16_11355	ENOG4108YZ4	nudix hydrolase
BW16_11360	ENOG4105CPC	Aldo Keto reductase
BW16_11385	ENOG4106HZJ	
BW16_11390	ENOG4108YQE	rare lipoprotein a
BW16_11395	ENOG4105RHY	Pfam:UPF0157
BW16_11400	ENOG4108XET	gCN5-related N-acetyltransferase
BW16_11410	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BW16_11420	ENOG4105E5W	Transporter
BW16_11425	ENOG4105DQ6	Transposase
BW16_11440	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BW16_11450	ENOG4108IXY	short-chain dehydrogenase reductase
BW16_11455	ENOG41069FQ	Metallo-beta-lactamase superfamily
BW16_11465	ENOG4105II7	pyrroline-5-carboxylate reductase
BW16_11480	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BW16_11490	ENOG4105XT2	Transcriptional regulator
BW16_11495	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BW16_11500	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
BW16_11505	ENOG4108TZY	GntR Family Transcriptional Regulator
BW16_11510	ENOG4105CS2	ec 3.2.1.21
BW16_11515	ENOG4105CK1	PTS System
BW16_11520	ENOG4105VCP	PTS System
BW16_11525	ENOG4105VZJ	PTS System
BW16_11530	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
BW16_11535	ENOG4105CSC	Glucose uptake protein
BW16_11540	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
BW16_11545	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BW16_11555	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
BW16_11560	ENOG4108V3W	Chemotaxis protein, CheW
BW16_11565	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
BW16_11570	ENOG4108HNZ	carboxyl transferase
BW16_11585	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
BW16_11590	ENOG4108QEG	Membrane
BW16_11595	ENOG4105CDA	abc transporter atp-binding protein
BW16_11600	ENOG4105E5Q	amino acid AbC transporter
BW16_11605	ENOG4108HW3	(ABC) transporter
BW16_11610	ENOG4108Y6J	UPF0403 protein
BW16_11615	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
BW16_11625	ENOG4105C7S	Dehydrogenase
BW16_11630	ENOG4105CPP	Dehydrogenase, E1 component
BW16_11645	ENOG4105CKM	Branched-chain carboxylic acid kinase
BW16_11650	ENOG4107RDP	Dehydrogenase
BW16_11660	ENOG4108JUB	Transcriptional regulator
BW16_11665	ENOG4106CCJ	Protein of unknown function (DUF2627)
BW16_11670	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BW16_11685	ENOG4107QQR	Sporulation
BW16_11690	ENOG4105S1Z	Stage IV sporulation protein B
BW16_11695	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BW16_11700	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
BW16_11705	ENOG4105DX0	Hemolysin A
BW16_11710	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BW16_11715	ENOG4105CTB	Polyprenyl synthetase
BW16_11720	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BW16_11725	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BW16_11730	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BW16_11735	ENOG4105M7K	Involved in the transcription termination process (By similarity)
BW16_11740	ENOG4108ZSR	alkaline shock protein
BW16_11745	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BW16_11765	ENOG410644B	Stage III sporulation protein af
BW16_11775	ENOG4105KQ4	Stage iii sporulation protein ad
BW16_11780	ENOG4108CQH	stage III sporulation protein AC
BW16_11785	ENOG4105KR5	Stage iii sporulation protein
BW16_11790	ENOG4105CD2	stage iii sporulation protein aa
BW16_11800	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BW16_11805	ENOG4105DC7	peptidase M24
BW16_11810	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BW16_11820	ENOG4105CBJ	Metal-dependent enzyme
BW16_11835	ENOG4105KST	dependent repressor
BW16_11840	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
BW16_11845	ENOG4105WZW	rhodanese family
BW16_11850	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BW16_11860	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BW16_11865	ENOG4105C0D	helicase
BW16_11890	ENOG4105VFR	signal peptidase
BW16_11930	ENOG4106855	Competence protein
BW16_11970	ENOG4105C5X	domain protein
BW16_11995	ENOG4105E0M	Sulfatase
BW16_12010	ENOG4107ZXI	Rhomboid family
BW16_12025	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BW16_12030	ENOG4105WDJ	50S ribosomal protein L33
BW16_12045	ENOG41068DG	YceG-like family
BW16_12050	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BW16_12055	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BW16_12060	ENOG4105E2Z	phosphate ABC transporter (Permease
BW16_12065	ENOG4105C8U	phosphate abc transporter
BW16_12070	ENOG4105CVA	phosphate
BW16_12075	ENOG4107RF6	penicillin-binding protein
BW16_12085	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BW16_12090	ENOG4105SXS	Protein of unknown function (DUF456)
BW16_12100	ENOG4105D9U	N-acetyltransferase
BW16_12110	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BW16_12115	ENOG41063Y9	
BW16_12120	ENOG4108U5J	'-nucleotidase
BW16_12125	ENOG41066F8	ROK family
BW16_12135	ENOG4105N80	Ferric uptake regulator, Fur family
BW16_12140	ENOG4105FAV	ABC, transporter
BW16_12145	ENOG4105FDK	ABC transporter
BW16_12150	ENOG4108JYZ	YitT family
BW16_12155	ENOG41069ZM	Protein of unknown function (DUF2624)
BW16_12160	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
BW16_12175	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BW16_12180	ENOG4105EGD	dinuclear metal center protein, YbgI family
BW16_12195	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BW16_12200	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BW16_12205	ENOG4108UPT	UPF0178 protein
BW16_12210	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BW16_12220	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
BW16_12225	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
BW16_12230	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
BW16_12240	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BW16_12245	ENOG4105KG3	cytidine deaminase
BW16_12250	ENOG4107YR5	Diacylglycerol kinase
BW16_12255	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BW16_12260	ENOG4105CTJ	Metal Dependent Phosphohydrolase
BW16_12265	ENOG4105C9A	Phoh family
BW16_12270	ENOG4105EI1	sporulation protein yqfd
BW16_12275	ENOG41068P3	sporulation protein YqfC
BW16_12285	ENOG4105DI5	UPF0365 protein
BW16_12290	ENOG4105F7J	membrane-bound serine protease
BW16_12295	ENOG4105KTH	gatB Yqey
BW16_12310	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BW16_12315	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
BW16_12320	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BW16_12325	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BW16_12335	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BW16_12340	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BW16_12345	ENOG4105CSA	Coproporphyrinogen iii oxidase
BW16_12350	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BW16_12360	ENOG4108ZRV	stage ii sporulation protein p
BW16_12375	ENOG4105TQK	DNA polymerase iii, delta' subunit
BW16_12385	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
BW16_12390	ENOG4108UK2	deaminase
BW16_12395	ENOG4105KQC	Competence protein
BW16_12405	ENOG4108D32	Methyltransferase
BW16_12415	ENOG4108WF2	Metal Dependent Phosphohydrolase
BW16_12420	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BW16_12425	ENOG410812S	Rna-binding protein
BW16_12430	ENOG4105E2X	shikimate dehydrogenase
BW16_12435	ENOG4105CQW	ribosome biogenesis GTPase YqeH
BW16_12440	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
BW16_12470	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BW16_12490	ENOG4107YCY	Transcriptional regulator
BW16_12505	ENOG4105CHR	reductase
BW16_12510	ENOG4108IUS	Transketolase
BW16_12515	ENOG4108HHA	Transketolase
BW16_12545	ENOG4108ZJ4	polysaccharide deacetylase
BW16_12580	ENOG4108IJ3	abc transporter atp-binding protein
BW16_12600	ENOG4107QNK	)-transporter
BW16_12610	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
BW16_12625	ENOG4105CMD	Transcriptional regulator, GntR family
BW16_12645	ENOG41080HJ	6-phospho 3-hexuloisomerase
BW16_12650	ENOG4108VA3	3-hexulose-6-phosphate synthase
BW16_12655	ENOG4105KVH	Transcriptional regulator
BW16_12720	ENOG4108HWY	Beta-lactamase
BW16_12725	ENOG4105FDT	acyl-CoA dehydrogenase
BW16_12745	ENOG4105E5Q	amino acid AbC transporter
BW16_12750	ENOG4105WEF	catalase
BW16_12770	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
BW16_12785	ENOG4107V2S	Transcriptional regulator
BW16_12790	ENOG4105E2A	Dehydrogenase
BW16_12815	ENOG4105C28	cystathionine
BW16_12830	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
BW16_12845	ENOG4107XRG	penicillin-binding protein
BW16_12850	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BW16_12855	ENOG4107S03	uridine kinase
BW16_12860	ENOG4105CFP	Peptidase U32
BW16_12865	ENOG4105XYU	peptidase (U32 family)
BW16_12870	ENOG4108VQJ	O-methyltransferase
BW16_12875	ENOG4105HHA	aminodeoxychorismate lyase
BW16_12885	ENOG4107F3J	Amp-dependent synthetase and ligase
BW16_12890	ENOG4107ZYJ	bioY protein
BW16_12895	ENOG4105VPH	UPF0473 protein
BW16_12900	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BW16_12905	ENOG4105VBH	UPF0297 protein
BW16_12915	ENOG4105C02	permease
BW16_12920	ENOG4105CDA	abc transporter atp-binding protein
BW16_12925	ENOG4105CT1	(ABC) transporter
BW16_12930	ENOG4105EAD	ABC transporter
BW16_12935	ENOG4105DRP	amino acid AbC transporter
BW16_12945	ENOG41060CR	
BW16_12955	ENOG4105C7H	Helicase, RecD TraA family
BW16_12965	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BW16_12970	ENOG4105C3J	Cysteine desulfurase
BW16_12980	ENOG4105D1H	recombination factor protein RarA
BW16_12985	ENOG4105CUZ	uba thif-type nad fad binding protein
BW16_12990	ENOG4105C9M	aspartyl-trna synthetase
BW16_12995	ENOG4105CUT	histidyl-tRNA synthetase
BW16_13005	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BW16_13010	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BW16_13015	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BW16_13020	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BW16_13025	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BW16_13030	ENOG41067VP	Protein of unknown function (DUF1049)
BW16_13035	ENOG4105NCW	Trka-c domain protein
BW16_13040	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BW16_13050	ENOG4105CKP	Polysaccharide Biosynthesis Protein
BW16_13055	ENOG4108QG2	Membrane
BW16_13060	ENOG4105NAP	
BW16_13065	ENOG4105VIE	preprotein translocase, subunit YajC
BW16_13070	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BW16_13075	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BW16_13080	ENOG41061AI	Protein of unknown function (DUF2905)
BW16_13085	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BW16_13090	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BW16_13115	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
BW16_13130	ENOG4106678	morphogenetic protein associated with SpoVID
BW16_13135	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
BW16_13140	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
BW16_13145	ENOG4108IYU	L-aspartate oxidase
BW16_13160	ENOG4105CQC	Prephenate dehydratase
BW16_13170	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BW16_13180	ENOG4105K46	50S ribosomal protein l27
BW16_13185	ENOG4105X36	(ribosomal) protein
BW16_13190	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BW16_13205	ENOG4107QMS	site-determining protein
BW16_13210	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
BW16_13215	ENOG4105YHC	Rod shape-determining protein MreD
BW16_13220	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
BW16_13225	ENOG4105DFF	Rod shape-determining protein mreb
BW16_13230	ENOG4105W5Q	DNA repair protein (RadC
BW16_13235	ENOG4108Z03	MAF-like protein
BW16_13245	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
BW16_13250	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BW16_13255	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BW16_13265	ENOG4106AR7	Spore coat protein
BW16_13270	ENOG41068KH	stage VI sporulation protein D
BW16_13275	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BW16_13280	ENOG4105D52	delta-aminolevulinic acid dehydratase
BW16_13290	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BW16_13300	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BW16_13310	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BW16_13315	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BW16_13320	ENOG4108IUQ	atp-dependent protease
BW16_13325	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BW16_13330	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BW16_13340	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BW16_13345	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BW16_13350	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BW16_13355	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BW16_13360	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BW16_13365	ENOG4108ZP8	Acetolactate synthase small subunit
BW16_13370	ENOG4105C7K	acetolactate synthase
BW16_13375	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BW16_13385	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
BW16_13395	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
BW16_13405	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
BW16_13410	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
BW16_13445	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
BW16_13450	ENOG4107EV6	Inherit from COG: YD repeat protein
BW16_13465	ENOG4105M59	Phosphodiesterase, mj0936 family
BW16_13470	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BW16_13475	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
BW16_13480	ENOG4108XJQ	germination protein
BW16_13485	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
BW16_13490	ENOG41067TZ	transcriptional regulator, MarR family
BW16_13495	ENOG4105PFC	Transcriptional regulator
BW16_13505	ENOG4108KAM	Transcriptional regulator
BW16_13510	ENOG4105C7F	AcnD-accessory protein PrpF
BW16_13515	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BW16_13525	ENOG4105E33	succinate dehydrogenase
BW16_13535	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
BW16_13545	ENOG4105CFH	Aspartokinase
BW16_13550	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BW16_13560	ENOG4105K63	Thioredoxin
BW16_13565	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
BW16_13575	ENOG4105BZJ	Electron transfer flavoprotein
BW16_13580	ENOG41060WC	Enoyl-CoA hydratase
BW16_13585	ENOG4107Z3H	Transcriptional regulator, TetR family
BW16_13590	ENOG4105CEY	Amp-dependent synthetase and ligase
BW16_13605	ENOG4105C98	muts2 protein
BW16_13610	ENOG4105DCG	PHP domain protein
BW16_13620	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
BW16_13625	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BW16_13630	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BW16_13635	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BW16_13640	ENOG4108RWN	rrna methyltransferase
BW16_13645	ENOG41067MF	small acid-soluble spore protein
BW16_13655	ENOG4105CN9	Peptidase m42 family protein
BW16_13665	ENOG410696E	Membrane
BW16_13670	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BW16_13675	ENOG4105VJV	50s ribosomal protein L35
BW16_13680	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BW16_13695	ENOG4105U0R	haloacid dehalogenase-like hydrolase
BW16_13700	ENOG4107SDU	Methyl-accepting chemotaxis
BW16_13705	ENOG4105C22	threonyL-tRNA synthetase
BW16_13710	ENOG4108TDW	sporulation protein YtxC
BW16_13730	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BW16_13740	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
BW16_13745	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BW16_13750	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BW16_13760	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BW16_13765	ENOG4105C2M	dna polymerase I
BW16_13770	ENOG4105BZU	Histidine kinase
BW16_13775	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BW16_13780	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BW16_13785	ENOG4108HMX	isocitrate dehydrogenase (NADP)
BW16_13790	ENOG4105BZN	citrate synthase
BW16_13795	ENOG4107CWS	Protein of unknown function (DUF441)
BW16_13800	ENOG4108REF	Sporulation integral membrane protein ytvi
BW16_13805	ENOG4105FS0	cytoplasmic membrane protein
BW16_13810	ENOG4105CA9	Pyruvate kinase
BW16_13815	ENOG4105CTQ	phosphohexokinase
BW16_13825	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BW16_13830	ENOG4105C6K	Malic enzyme
BW16_13835	ENOG4105C0B	DNA polymerase III (alpha subunit)
BW16_13840	ENOG4105VV2	
BW16_13850	ENOG4106EVM	
BW16_13855	ENOG4105SFS	phosphoesterase RecJ domain protein
BW16_13875	ENOG4105E8R	UPF0173 metal-dependent hydrolase
BW16_13890	ENOG4105CH7	arginosuccinase
BW16_13895	ENOG4105CDH	Citrulline--aspartate ligase
BW16_13900	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
BW16_13905	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BW16_13915	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
BW16_13920	ENOG4105KBJ	sporulation protein ytfj
BW16_13930	ENOG4105VK3	rdd domain containing protein
BW16_13935	ENOG4105D07	Signal peptide peptidase, SppA
BW16_13940	ENOG4108KKH	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BW16_13950	ENOG4105C1J	atp-dependent rna helicase
BW16_13955	ENOG4105ECK	Fatty Acid Desaturase
BW16_13965	ENOG4108ZGX	Histidine kinase
BW16_13970	ENOG4108S01	response regulator
BW16_13980	ENOG4105CJZ	response regulator
BW16_13985	ENOG4105EWM	Histidine kinase
BW16_13990	ENOG4105C19	ABC transporter
BW16_14000	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
BW16_14005	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
BW16_14025	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
BW16_14030	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BW16_14040	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
BW16_14070	ENOG4105U5Y	Transcriptional regulator
BW16_14080	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BW16_14105	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
BW16_14110	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
BW16_14115	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BW16_14125	ENOG4105F1V	Acetoin utilization protein
BW16_14130	ENOG4105W87	Cbs domain
BW16_14135	ENOG4105DGU	Histone deacetylase
BW16_14140	ENOG4105ETE	Transcriptional regulator (LacI family
BW16_14150	ENOG4105DQ6	Transposase
BW16_14155	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
BW16_14175	ENOG4105DFU	Cell wall formation (By similarity)
BW16_14185	ENOG4108VDD	TRNA binding domain protein
BW16_14190	ENOG4108NKM	UPF0354 protein
BW16_14205	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
BW16_14220	ENOG4105C6K	Malic enzyme
BW16_14225	ENOG4105C8F	Beta-lactamase domain protein
BW16_14230	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BW16_14240	ENOG4108V15	phosphotransferase enzyme family
BW16_14255	ENOG4107F58	2'-5' rna ligase
BW16_14260	ENOG4105C6T	cysteine synthase
BW16_14265	ENOG4107UIE	peptidase
BW16_14270	ENOG4107QSE	Dipeptidase
BW16_14275	ENOG4105C7N	Xanthine uracil vitamin C permease
BW16_14280	ENOG4105YW5	deoR family transcriptional regulator
BW16_14295	ENOG4105CBX	hi0933 family
BW16_14305	ENOG4105C94	Transporter
BW16_14310	ENOG4106611	bacteriocin immunity
BW16_14320	ENOG41085GJ	domain protein
BW16_14325	ENOG4105MU9	integral membrane protein
BW16_14330	ENOG4105DDC	Oxidoreductase domain protein
BW16_14340	ENOG4105F5H	Glycosyl Hydrolase Family 88
BW16_14350	ENOG41075H3	AraC family transcriptional regulator
BW16_14355	ENOG4105KVH	Transcriptional regulator
BW16_14360	ENOG4105F27	Major Facilitator
BW16_14365	ENOG4105CV8	reductase
BW16_14375	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BW16_14385	ENOG4105NTD	Inherit from COG: Hydrolase
BW16_14390	ENOG4105C8T	Leucyl-tRNA synthetase
BW16_14405	ENOG4105BZU	Histidine kinase
BW16_14410	ENOG4106UBQ	
BW16_14415	ENOG4107R34	abc transporter permease protein
BW16_14420	ENOG4105C19	ABC transporter
BW16_14430	ENOG4105DVE	abc transporter atp-binding protein
BW16_14435	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
BW16_14455	ENOG4105N5T	Radical SAM Protein
BW16_14465	ENOG4108N23	SpoOM-related protein
BW16_14475	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
BW16_14480	ENOG4108Z0R	Transferase
BW16_14485	ENOG4105CAQ	asparagine synthetase
BW16_14490	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BW16_14510	ENOG4105EWK	phytoene
BW16_14530	ENOG4105D2X	ABC transporter substrate-binding protein
BW16_14540	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
BW16_14550	ENOG4106FN3	tellurium resistance protein
BW16_14575	ENOG4108RMU	ferritin dps family protein
BW16_14590	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
BW16_14595	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
BW16_14600	ENOG4108V2W	Carbonate dehydratase
BW16_14605	ENOG4105DSE	periplasmic solute binding protein
BW16_14610	ENOG4105NRA	50s ribosomal protein l31 type b
BW16_14635	ENOG4105DTQ	mandelate racemase muconate lactonizing
BW16_14645	ENOG4108IPT	Naphthoate synthase
BW16_14650	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
BW16_14655	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
BW16_14660	ENOG4105E4F	Isochorismate synthase
BW16_14665	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
BW16_14675	ENOG4108606	TspO/MBR family
BW16_14800	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
BW16_14805	ENOG4105VRR	gCN5-related N-acetyltransferase
BW16_14815	ENOG4105CNI	cell division protein FtsW
BW16_14820	ENOG4105CNI	cell division protein FtsW
BW16_14825	ENOG4105DZ6	Band 7 protein
BW16_14835	ENOG4106DF1	
BW16_14840	ENOG4108JB8	alcohol dehydrogenase
BW16_14845	ENOG4105C26	Dehydrogenase
BW16_14850	ENOG4105TRT	Transcriptional regulator
BW16_14865	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
BW16_14905	ENOG41068G1	
BW16_14935	ENOG410906S	phage-like element pbsx protein xkdt
BW16_14940	ENOG41066EA	baseplate J family protein
BW16_14945	ENOG4105MFU	Protein of unknown function (DUF2634)
BW16_14955	ENOG4105X7F	
BW16_14960	ENOG4108WZM	domain protein
BW16_14965	ENOG4108FKH	Transglycosylase SLT domain
BW16_14975	ENOG4105MTC	XkdN-like protein
BW16_14985	ENOG4105FR7	XkdM protein, phage-like element PBSX
BW16_14990	ENOG4105PQS	phage protein
BW16_15005	ENOG41060SN	
BW16_15035	ENOG4105IG6	Phage terminase, large subunit
BW16_15055	ENOG4105QBX	endodeoxyribonuclease RusA
BW16_15090	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BW16_15100	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BW16_15115	ENOG4105EE0	oxidoreductase
BW16_15120	ENOG4108Z0Z	intracellular protease Pfpi family
BW16_15125	ENOG4105C8Q	Methyl-accepting chemotaxis
BW16_15130	ENOG4105C8Q	Methyl-accepting chemotaxis
BW16_15135	ENOG4105C8Q	Methyl-accepting chemotaxis
BW16_15140	ENOG4105C8Q	Methyl-accepting chemotaxis
BW16_15155	ENOG4105EA8	2-Nitropropane dioxygenase
BW16_15160	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
BW16_15165	ENOG4105C37	(CBS) domain
BW16_15180	ENOG4107PBV	potassium channel
BW16_15210	ENOG4107QW4	alcohol dehydrogenase
BW16_15215	ENOG4105WG9	Conserved Protein
BW16_15225	ENOG4105CHM	Aminotransferase
BW16_15230	ENOG4108ZB6	transcriptional regulator AsnC family
BW16_15235	ENOG4108MUZ	hydrolase
BW16_15245	ENOG4105C87	Aminotransferase class I and II
BW16_15250	ENOG4108HGU	Histidine kinase
BW16_15260	ENOG4105Y38	Kinase-associated protein B
BW16_15275	ENOG4105BZ4	penicillin-binding protein
BW16_15280	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
BW16_15295	ENOG4108MRH	transcriptional regulatory protein
BW16_15300	ENOG4105DIH	basic membrane
BW16_15305	ENOG4108JQ9	ABC transporter
BW16_15310	ENOG4105UIB	(ABC) transporter
BW16_15330	ENOG4105D65	subunit l
BW16_15335	ENOG4105HC0	Na H antiporter
BW16_15340	ENOG4108ZE9	Monovalent cation H antiporter subunit C
BW16_15345	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BW16_15350	ENOG4105SC1	monovalent cation H antiporter subunit E
BW16_15360	ENOG4105KJM	monovalent cation h antiporter subunit g
BW16_15365	ENOG4105KA0	thioesterase Superfamily protein
BW16_15375	ENOG4105BZU	Histidine kinase
BW16_15400	ENOG4105D58	Diguanylate phosphodiesterase
BW16_15405	ENOG4105DAP	Nicotinate phosphoribosyltransferase
BW16_15435	ENOG4105C02	permease
BW16_15455	ENOG410904N	short-chain dehydrogenase reductase
BW16_15490	ENOG4108K8K	Transcriptional regulator
BW16_15495	ENOG4105DCF	alanine dehydrogenase
BW16_15510	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BW16_15520	ENOG41069ER	domain protein
BW16_15535	ENOG4105CEP	NADH dehydrogenase
BW16_15540	ENOG4105CAY	ferredoxin--nadp reductase
BW16_15560	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
BW16_15565	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BW16_15570	ENOG4105ZKE	UPF0349 protein
BW16_15590	ENOG41083MR	nifu domain-containing protein
BW16_15595	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BW16_15605	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
BW16_15610	ENOG4105D6E	homoserine dehydrogenase
BW16_15615	ENOG4105C5I	Dehydrogenase
BW16_15625	ENOG4108W5N	phosphatidylglycerophosphatase a
BW16_15630	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
BW16_15640	ENOG4105MMD	transcriptional regulator
BW16_15645	ENOG4106EGE	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
BW16_15655	ENOG4105FAA	peptidase M23
BW16_15670	ENOG4108YTE	sporulation protein YunB
BW16_15675	ENOG4105KZD	Domain of unknown function (DUF1805)
BW16_15680	ENOG4107R8B	5'-nucleotidase
BW16_15685	ENOG4105I3N	Conserved Protein
BW16_15690	ENOG4105G9B	Transcriptional regulator
BW16_15695	ENOG4105F0F	Oxalate decarboxylase
BW16_15705	ENOG4105C5R	Aminotransferase
BW16_15710	ENOG4108K8S	endonuclease I
BW16_15725	ENOG4108IHU	transport system permease protein
BW16_15730	ENOG4105DQ5	transport system permease protein
BW16_15735	ENOG4108MES	Periplasmic binding protein
BW16_15750	ENOG4108HCJ	Hydrolase
BW16_15760	ENOG4108SWU	Histidine kinase
BW16_15765	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BW16_15770	ENOG4105DHF	Membrane
BW16_15780	ENOG4107YCK	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
BW16_15790	ENOG4108IG5	Transcriptional regulator
BW16_15805	ENOG4105DIW	FeS assembly protein SUFB
BW16_15810	ENOG4108UNV	SUF system FeS assembly protein, NifU family
BW16_15815	ENOG4105C9B	Cysteine desulfurase
BW16_15820	ENOG4105JRK	feS assembly protein SufD
BW16_15825	ENOG4105C3K	feS assembly ATPase SufC
BW16_15840	ENOG4105D01	(LipO)protein
BW16_15845	ENOG4108UMI	ABC transporter, permease
BW16_15850	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BW16_15875	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BW16_15880	ENOG41080E8	Transcriptional regulator, Spx MgsR family
BW16_15885	ENOG4105C1G	acyl-Coa dehydrogenase
BW16_15890	ENOG4105CHU	acetyl-coa acetyltransferase
BW16_15920	ENOG4105E0A	ABC, transporter
BW16_15930	ENOG4105E1F	short-chain dehydrogenase reductase
BW16_15935	ENOG4105C0H	protease
BW16_15945	ENOG4105F3H	Histidine kinase
BW16_15955	ENOG41067SE	Tetr family transcriptional regulator
BW16_15965	ENOG4105C9Q	fumarate hydratase class II
BW16_15995	ENOG4105WH1	Two component transcriptional regulator luxr family
BW16_16000	ENOG4105ENE	Histidine kinase
BW16_16015	ENOG41087YS	Phage shock protein A
BW16_16025	ENOG4108WBT	adenosyltransferase
BW16_16030	ENOG4105CHR	reductase
BW16_16035	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
BW16_16040	ENOG4107S2N	Type III effector Hrp-dependent
BW16_16045	ENOG4108JUA	Transcriptional regulator
BW16_16060	ENOG4105C0A	alcohol dehydrogenase
BW16_16065	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BW16_16070	ENOG4105E0A	ABC, transporter
BW16_16075	ENOG4105EHG	Permease protein
BW16_16080	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
BW16_16090	ENOG4105CTX	dehydratase
BW16_16095	ENOG4107QZW	Altronate oxidoreductase
BW16_16100	ENOG4107KJX	Transcriptional regulator
BW16_16105	ENOG4105D2H	Uronic isomerase
BW16_16115	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BW16_16120	ENOG4105E0A	ABC, transporter
BW16_16125	ENOG4105EHG	Permease protein
BW16_16130	ENOG4105DQ5	transport system permease protein
BW16_16140	ENOG4105D5Q	Arginine ornithine antiporter
BW16_16155	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
BW16_16160	ENOG4107QZ2	Sulfatase
BW16_16165	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
BW16_16170	ENOG4105E0C	molybdate abc transporter
BW16_16180	ENOG4105EVU	fructokinase
BW16_16185	ENOG4107SUZ	Sodium/hydrogen exchanger family
BW16_16190	ENOG4105EN6	Membrane
BW16_16200	ENOG4107ZQN	disulfide bond
BW16_16205	ENOG4105C59	p-type ATPase
BW16_16210	ENOG4105DIK	(ABC) transporter
BW16_16215	ENOG4105CC5	ABC transporter
BW16_16220	ENOG4105DSE	periplasmic solute binding protein
BW16_16225	ENOG4105IIP	Membrane
BW16_16230	ENOG4105W1N	transcriptional regulator
BW16_16245	ENOG4108IJ0	Aspartate ammonia-lyase
BW16_16260	ENOG4105C59	p-type ATPase
BW16_16265	ENOG410681U	heavy metal transport detoxification protein
BW16_16270	ENOG4105VPX	protein, conserved in bacteria
BW16_16280	ENOG4105BZU	Histidine kinase
BW16_16290	ENOG4107SJB	teichoic acid biosynthesis
BW16_16295	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BW16_16300	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BW16_16310	ENOG4105XZU	Preprotein translocase, subunit SecG
BW16_16335	ENOG4105KVH	Transcriptional regulator
BW16_16340	ENOG4105R40	Glycine betaine carnitine choline
BW16_16345	ENOG4108HQR	Glycine betaine
BW16_16350	ENOG4105E90	ABC transporter
BW16_16355	ENOG4108IJ8	ABC transporter
BW16_16360	ENOG4107HG4	Transcriptional regulator
BW16_16365	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
BW16_16375	ENOG4108W0I	acetyltransferase
BW16_16405	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BW16_16415	ENOG4105CP7	Triose-phosphate isomerase
BW16_16420	ENOG4105BZA	Phosphoglycerate kinase
BW16_16425	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BW16_16440	ENOG4105C8Y	Acetylornithine aminotransferase
BW16_16445	ENOG4108JUB	Transcriptional regulator
BW16_16450	ENOG4105JXH	GntR family transcriptional regulator
BW16_16460	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BW16_16470	ENOG4107R73	Mate efflux family protein
BW16_16475	ENOG4108JQ7	(ABC) transporter
BW16_16480	ENOG4105C3U	ABC transporter
BW16_16485	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BW16_16490	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BW16_16495	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
BW16_16500	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BW16_16505	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
BW16_16510	ENOG4105D3Q	Sugar transferase
BW16_16525	ENOG4107QRS	glycosyltransferase group 2 family protein
BW16_16530	ENOG41068W6	Capsular polysaccharide biosynthesis protein
BW16_16535	ENOG4108KMV	Glycosyl transferase (Group 1
BW16_16540	ENOG4105K64	Glycosyl transferase, family 2
BW16_16555	ENOG4108QV3	biosynthesis protein
BW16_16560	ENOG4105HTX	biosynthesis protein
BW16_16575	ENOG4108V5C	ABC transporter
BW16_16580	ENOG4105EHG	Permease protein
BW16_16585	ENOG4105DQ5	transport system permease protein
BW16_16590	ENOG4108ZJ4	polysaccharide deacetylase
BW16_16600	ENOG4108JQ7	(ABC) transporter
BW16_16615	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BW16_16620	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
BW16_16630	ENOG4108MES	Periplasmic binding protein
BW16_16645	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BW16_16650	ENOG4108URH	decarboxylase
BW16_16655	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
BW16_16660	ENOG4105CHH	sulfate transporter
BW16_16665	ENOG4108V2W	Carbonate dehydratase
BW16_16675	ENOG4105C5I	Dehydrogenase
BW16_16685	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
BW16_16690	ENOG4105KRI	phosphocarrier protein (HPr
BW16_16695	ENOG4105CIE	May be required for sporulation (By similarity)
BW16_16700	ENOG4105CHW	UPF0052 protein
BW16_16705	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BW16_16710	ENOG4108Z4K	mutator MutT protein
BW16_16715	ENOG4105C3M	thioredoxin reductase
BW16_16730	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BW16_16735	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BW16_16740	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BW16_16745	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BW16_16750	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BW16_16755	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BW16_16760	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BW16_16765	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
BW16_16775	ENOG4108RYK	Nad-dependent epimerase dehydratase
BW16_16780	ENOG4108Z40	Transcriptional regulator
BW16_16785	ENOG4108S4C	acetyltransferase
BW16_16790	ENOG4107XGZ	Hydrolase
BW16_16795	ENOG4105HKU	nucleoside recognition domain-containing protein
BW16_16805	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BW16_16810	ENOG4105CE4	GlcNAc 6-P deacetylase
BW16_16815	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
BW16_16820	ENOG4105FDP	GntR family transcriptional regulator
BW16_16825	ENOG41088CQ	domain protein
BW16_16830	ENOG41086DT	Membrane protein of unknown function
BW16_16835	ENOG41067S9	phage shock protein C, PspC
BW16_16840	ENOG4108PY7	
BW16_16855	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BW16_16860	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BW16_16880	ENOG4105MKU	Transcriptional regulator
BW16_16895	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BW16_16900	ENOG4105BZU	Histidine kinase
BW16_16905	ENOG4105EDW	glycosyl transferase, family 39
BW16_16910	ENOG4105CKK	Glycosyl transferase, family 2
BW16_16920	ENOG4108RCM	Nitroreductase
BW16_16925	ENOG4105KVH	Transcriptional regulator
BW16_16940	ENOG4105CN1	protease
BW16_16955	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
BW16_16960	ENOG4105CAK	Cell division ATP-binding protein ftsE
BW16_16985	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BW16_16995	ENOG4105MS2	ribosomal subunit Interface protein
BW16_17000	ENOG4105C8Q	Methyl-accepting chemotaxis
BW16_17015	ENOG4105MQ3	flagellar protein FliS
BW16_17020	ENOG4107RT6	flagellar hook-associated
BW16_17025	ENOG41083S7	flagellar protein FlaG
BW16_17030	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
BW16_17035	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
BW16_17040	ENOG4105MKD	
BW16_17045	ENOG4105DTJ	flagellar hook-associated protein
BW16_17050	ENOG4105E1Q	flagellar hook-associated protein
BW16_17065	ENOG4105RU3	
BW16_17070	ENOG41081UC	Inherit from COG: Competence protein
BW16_17090	ENOG4105WH1	Two component transcriptional regulator luxr family
BW16_17095	ENOG4105BZU	Histidine kinase
BW16_17100	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BW16_17105	ENOG4108KGH	TRANSCRIPTIONal
BW16_17110	ENOG4105ESV	Glycosyl transferase, family 4
BW16_17115	ENOG4107EF8	Glycosyl transferase (Group 1
BW16_17130	ENOG4105QZI	O-Antigen Polymerase
BW16_17135	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
BW16_17140	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BW16_17145	ENOG4107RA4	Glycosyl transferase (Group 1
BW16_17150	ENOG4105PSV	Polysaccharide Biosynthesis Protein
BW16_17155	ENOG4105D3Q	Sugar transferase
BW16_17165	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BW16_17170	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BW16_17175	ENOG4105JFG	SpoIID LytB domain protein
BW16_17190	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BW16_17195	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BW16_17200	ENOG4105EY8	ABC transporter
BW16_17240	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
BW16_17250	ENOG4107RZX	Teichoic acid biosynthesis protein
BW16_17260	ENOG4105DG6	mannose-6-phosphate isomerase
BW16_17270	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BW16_17275	ENOG4108JP0	extracellular solute-binding protein family 1
BW16_17280	ENOG4105WH1	Two component transcriptional regulator luxr family
BW16_17285	ENOG4105C2F	Histidine kinase
BW16_17295	ENOG4105I4A	GCN5-related N-acetyltransferase
BW16_17300	ENOG4108UHU	Aldolase
BW16_17305	ENOG4105D7K	pfkb domain protein
BW16_17310	ENOG4108M60	Transcriptional regulator
BW16_17315	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
BW16_17320	ENOG4105CHR	reductase
BW16_17335	ENOG4108NHD	germination protein
BW16_17340	ENOG4107RGC	Glycosyl transferase, family 2
BW16_17345	ENOG4105C54	Major Facilitator superfamily
BW16_17350	ENOG4108KGH	TRANSCRIPTIONal
BW16_17355	ENOG4105J7I	hydrolase
BW16_17360	ENOG4105K4H	Nlp p60 protein
BW16_17370	ENOG4105PNM	synthesis protein
BW16_17380	ENOG4105N98	Capsule biosynthesis protein capB
BW16_17400	ENOG4105ETE	Transcriptional regulator (LacI family
BW16_17405	ENOG4108RVA	ribokinase
BW16_17410	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
BW16_17415	ENOG4105C2J	ABC transporter
BW16_17420	ENOG4105CNN	ABC, transporter
BW16_17425	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
BW16_17430	ENOG4107XC4	flavin reductase domain protein, FMN-binding
BW16_17435	ENOG4107RSM	transcriptional regulator
BW16_17445	ENOG4107FQX	Alpha-acetolactate decarboxylase
BW16_17455	ENOG4105CAH	Chromate
BW16_17460	ENOG4105FGV	Chromate
BW16_17465	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BW16_17475	ENOG4105KBK	Zinc finger, swim domain protein
BW16_17480	ENOG4105C0D	helicase
BW16_17485	ENOG4105BZU	Histidine kinase
BW16_17490	ENOG410667J	hydrolase
BW16_17505	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BW16_17510	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BW16_17520	ENOG4105CGA	flagellar basal-body rod protein FlgG
BW16_17535	ENOG4105DFF	Rod shape-determining protein mreb
BW16_17540	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
BW16_17545	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
BW16_17550	ENOG4105CZM	Major Facilitator
BW16_17555	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
BW16_17560	ENOG41080V3	Major Facilitator superfamily
BW16_17565	ENOG4105EAB	amino acid AbC transporter
BW16_17570	ENOG4105E5Q	amino acid AbC transporter
BW16_17575	ENOG4105CDA	abc transporter atp-binding protein
BW16_17580	ENOG4105BZU	Histidine kinase
BW16_17590	ENOG4105FRN	stage II sporulation protein
BW16_17595	ENOG4107TCE	N-acetyltransferase
BW16_17605	ENOG4105WDJ	50S ribosomal protein L33
BW16_17610	ENOG4105CKI	cobalamin synthesis protein
BW16_17615	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BW16_17625	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
BW16_17630	ENOG4105FCD	Major Facilitator
BW16_17635	ENOG4108J2R	molybdopterin oxidoreductase
BW16_17640	ENOG4108TF4	von Willebrand factor, type A
BW16_17655	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BW16_17665	ENOG4106778	Protein of unknown function (DUF1146)
BW16_17675	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BW16_17680	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BW16_17685	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BW16_17690	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BW16_17710	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
BW16_17725	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BW16_17730	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BW16_17735	ENOG4108UIC	UPF0340 protein
BW16_17740	ENOG4108YZG	isomerase
BW16_17745	ENOG4107WAU	Protein tyrosine phosphatase
BW16_17755	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BW16_17765	ENOG4108ZXQ	stage ii sporulation protein r
BW16_17775	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BW16_17780	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BW16_17790	ENOG4107TT2	Auxin Efflux Carrier
BW16_17795	ENOG4105C6K	Malic enzyme
BW16_17800	ENOG4107104	thymidine kinase
BW16_17805	ENOG41082DI	50s ribosomal protein l31
BW16_17810	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
BW16_17815	ENOG4105CBT	Fructose-1,6-bisphosphatase
BW16_17820	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BW16_17830	ENOG4105D2N	Aldolase
BW16_17835	ENOG410812K	response regulator receiver protein
BW16_17845	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BW16_17855	ENOG41081I9	integral membrane protein
BW16_17865	ENOG4105C1G	acyl-Coa dehydrogenase
BW16_17870	ENOG4105C1G	acyl-Coa dehydrogenase
BW16_17875	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BW16_17885	ENOG4105DF6	Fe-S oxidoreductase
BW16_17905	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
BW16_17915	ENOG4105BZ1	(ABC) transporter
BW16_17920	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BW16_17935	ENOG4105C75	arginyL-tRNA synthetase
BW16_17940	ENOG410684U	Domain of unknown function (DUF1934)
BW16_17950	ENOG4105CYW	agmatinase
BW16_17955	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
BW16_17960	ENOG4105BZ4	penicillin-binding protein
BW16_17965	ENOG4108XFG	YwhD family
BW16_17970	ENOG4108Z4T	Peptidase M50
BW16_17975	ENOG41069HH	4-oxalocrotonate tautomerase
BW16_17990	ENOG4108KSA	LysR family transcriptional regulator
BW16_17995	ENOG4108UZX	fmn reductase
BW16_18000	ENOG4105DEN	Luciferase family
BW16_18010	ENOG4108XSB	acetyltransferase, (GNAT) family
BW16_18025	ENOG4105E5Q	amino acid AbC transporter
BW16_18030	ENOG4105CDA	abc transporter atp-binding protein
BW16_18040	ENOG4105DCI	Phosphohydrolase
BW16_18045	ENOG4105QAT	UPF0741 protein
BW16_18050	ENOG4108VCI	transcription factor, rsfa family
BW16_18060	ENOG4107QZ7	Cellulose synthase catalytic subunit
BW16_18070	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
BW16_18095	ENOG4107EV6	Inherit from COG: YD repeat protein
BW16_18125	ENOG4105JSC	dimethylmenaquinone methyltransferase
BW16_18135	ENOG4108IJ2	phosphate acetyltransferase
BW16_18140	ENOG4107JTW	chlorite dismutase
BW16_18145	ENOG4105F27	Major Facilitator
BW16_18155	ENOG4105FCW	Major Facilitator superfamily
BW16_18160	ENOG41061WN	bacilysin biosynthesis protein
BW16_18165	ENOG4106CHD	Bacilysin biosynthesis protein bacB
BW16_18170	ENOG4105CHR	reductase
BW16_18175	ENOG4108V3M	Inherit from COG: acetyl-CoA carboxylase biotin carboxylase
BW16_18180	ENOG4105CHM	Aminotransferase
BW16_18190	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
BW16_18195	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
BW16_18200	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
BW16_18205	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
BW16_18210	ENOG4107P9E	Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG
BW16_18215	ENOG4107TY6	Acylneuraminate cytidylyltransferase
BW16_18225	ENOG41067MN	Spore coat polysaccharide biosynthesis protein spsD
BW16_18230	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BW16_18275	ENOG4105C26	Dehydrogenase
BW16_18280	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BW16_18285	ENOG4108RJ9	Glycosyl transferase, family 2
BW16_18295	ENOG4105DWF	phosphomethylpyrimidine kinase
BW16_18315	ENOG4105C5Y	PTS System
BW16_18330	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
BW16_18340	ENOG4105DEN	Luciferase family
BW16_18345	ENOG4108DBC	nitroreductase
BW16_18360	ENOG41060D1	Quinol oxidase
BW16_18365	ENOG4105CCU	oxidase (Subunit III)
BW16_18370	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BW16_18375	ENOG4105E2S	oxidase) subunit II
BW16_18390	ENOG4105CMR	udp-glucose 4-epimerase
BW16_18395	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BW16_18410	ENOG4105WH5	Teichoic acid glycosylation protein
BW16_18455	ENOG4107U6I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BW16_18460	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
BW16_18465	ENOG4105CMU	LysR family (Transcriptional regulator
BW16_18475	ENOG41067MG	lrgb family
BW16_18480	ENOG4105DR4	Methyltransferase
BW16_18495	ENOG4105E5Q	amino acid AbC transporter
BW16_18500	ENOG4107R0W	ABC transporter
BW16_18525	ENOG4105CNN	ABC, transporter
BW16_18530	ENOG4105C2J	ABC transporter
BW16_18535	ENOG4108QGH	periplasmic
BW16_18545	ENOG4108M26	parallel beta-helix repeat protein
BW16_18550	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BW16_18565	ENOG4105F8D	glycoside hydrolase family 4
BW16_18570	ENOG4105VCP	PTS System
BW16_18575	ENOG4105CK1	PTS System
BW16_18580	ENOG4105VZJ	PTS System
BW16_18585	ENOG4105EMD	TRANSCRIPTIONal
BW16_18605	ENOG4107R37	Glutamate dehydrogenase
BW16_18625	ENOG4108J20	pectate lyase
BW16_18630	ENOG4108JJ8	(ABC) transporter
BW16_18635	ENOG4108JJ9	ABC, transporter
BW16_18640	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BW16_18645	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BW16_18650	ENOG4105E0A	ABC, transporter
BW16_18655	ENOG4105DQ5	transport system permease protein
BW16_18660	ENOG4108HUF	Transporter
BW16_18665	ENOG4105KFN	sortase, SrtB family
BW16_18690	ENOG4106ST0	Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity)
BW16_18695	ENOG4106ST0	Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity)
BW16_18705	ENOG4105KVH	Transcriptional regulator
BW16_18710	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
BW16_18715	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BW16_18720	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
BW16_18730	ENOG4107BJW	polysaccharide deacetylase
BW16_18735	ENOG4105VCP	PTS System
BW16_18740	ENOG4105VZJ	PTS System
BW16_18745	ENOG4105CS2	ec 3.2.1.21
BW16_18750	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
BW16_18755	ENOG4105CK1	PTS System
BW16_18785	ENOG4105DFD	Na H antiporter
BW16_18790	ENOG4108IJ0	Aspartate ammonia-lyase
BW16_18795	ENOG4105HDK	L-asparaginase
BW16_18800	ENOG4108IMY	Transcriptional regulator
BW16_18830	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
BW16_18840	ENOG4105DQ6	Transposase
BW16_18855	ENOG4106KNT	transcriptional regulator
BW16_18860	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BW16_18870	ENOG4105C6Z	Gluconate
BW16_18905	ENOG4105CS2	ec 3.2.1.21
BW16_18910	ENOG4105C5Y	PTS System
BW16_18915	ENOG4105CID	antiterminator
BW16_18920	ENOG4108XI2	Domain of unknown function (DUF1963)
BW16_18930	ENOG4108W7F	transporter, permease
BW16_18935	ENOG4108JJB	ABC transporter
BW16_18940	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
BW16_18945	ENOG4105ETU	transcriptional activator (TenA
BW16_18975	ENOG4107G87	m6 family metalloprotease domain protein
BW16_18980	ENOG41067V3	Antibiotic biosynthesis monooxygenase
BW16_18985	ENOG4108TVJ	Nitroreductase
BW16_18990	ENOG4105FS7	Transcriptional regulator
BW16_19000	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
BW16_19005	ENOG4105D9N	nucleoside
BW16_19010	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BW16_19015	ENOG4107RHR	regulatoR
BW16_19025	ENOG4105EXC	Acyl-transferase
BW16_19030	ENOG4105DXI	Major Facilitator superfamily
BW16_19035	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BW16_19040	ENOG4105HMZ	Methyltransferase
BW16_19050	ENOG410667J	hydrolase
BW16_19055	ENOG4105W1Y	Transcriptional regulator
BW16_19060	ENOG4105EE0	oxidoreductase
BW16_19065	ENOG4105DQ6	Transposase
BW16_19075	ENOG4105FKZ	Methyl-accepting chemotaxis
BW16_19090	ENOG4105F1N	DNA alkylation repair
BW16_19095	ENOG4105C6Z	Gluconate
BW16_19100	ENOG4105CMG	Carbohydrate kinase
BW16_19105	ENOG4106KNT	transcriptional regulator
BW16_19150	ENOG4105DUM	transcriptional regulator, lysR family
BW16_19160	ENOG4107FKK	extracellular solute-binding protein family 1
BW16_19170	ENOG4105EG2	ABC transporter, permease
BW16_19180	ENOG4105C4C	beta-galactosidase
BW16_19215	ENOG4105D4T	Citrate transporter
BW16_19225	ENOG4108TU7	Inherit from COG: (ABC) transporter
BW16_19230	ENOG4105CJ1	ABC, transporter
BW16_19240	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
BW16_19245	ENOG4105BZW	Glycerate kinase
BW16_19250	ENOG4107QQ0	gntp family
BW16_19255	ENOG4107VHA	regulatoR
BW16_19260	ENOG4105YA8	Transcriptional regulator
BW16_19265	ENOG4107Y80	Major Facilitator superfamily
BW16_19275	ENOG4105C19	ABC transporter
BW16_19285	ENOG410780I	phosphoprotein phosphatase activity
BW16_19290	ENOG4105CID	antiterminator
BW16_19295	ENOG4105CS2	ec 3.2.1.21
BW16_19300	ENOG4105C5Y	PTS System
BW16_19330	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
BW16_19350	ENOG4105C85	amino acid
BW16_19355	ENOG4105ETE	Transcriptional regulator (LacI family
BW16_19365	ENOG4105E2X	shikimate dehydrogenase
BW16_19375	ENOG4105CS2	ec 3.2.1.21
BW16_19385	ENOG4105C5Y	PTS System
BW16_19425	ENOG4105CS2	ec 3.2.1.21
BW16_19430	ENOG4105C5Y	PTS System
BW16_19435	ENOG4108S3Y	transcriptional regulator
BW16_19450	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BW16_19455	ENOG41080UQ	Transcriptional regulator
BW16_19475	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
BW16_19490	ENOG4105BZU	Histidine kinase
BW16_19500	ENOG4105EYF	MMPL domain protein
BW16_19505	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BW16_19515	ENOG4105DCI	Phosphohydrolase
BW16_19520	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BW16_19530	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
BW16_19540	ENOG4108V7D	UPF0397 protein
BW16_19560	ENOG4105WQG	acetyltransferase
BW16_19565	ENOG4105C0H	protease
BW16_19570	ENOG4105Q2H	domain protein
BW16_19585	ENOG4105BZU	Histidine kinase
BW16_19590	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BW16_19615	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BW16_19630	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BW16_19635	ENOG4105ST3	Transcriptional regulator
BW16_19640	ENOG4106A3M	Cytochrome p-450
BW16_19645	ENOG4105HB7	Glyoxalase Bleomycin resistance protein (Dioxygenase
BW16_19650	ENOG4105CDU	Replicative dna helicase
BW16_19655	ENOG4106K80	
BW16_19660	ENOG4106K80	
BW16_19675	ENOG4105NIV	Esterase
BW16_19680	ENOG410874W	AraC family transcriptional regulator
BW16_19690	ENOG4108SA1	esterase
BW16_19700	ENOG4105DJ2	Major Facilitator Superfamily
BW16_19705	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BW16_19710	ENOG4105BZR	domain protein
BW16_19715	ENOG4108XMW	Membrane
BW16_19720	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
BW16_19725	ENOG4108P49	AntiSigma factor
BW16_19730	ENOG4105JVQ	RNA Polymerase
BW16_19740	ENOG4105CH6	catalase
BW16_19745	ENOG4105CS1	NAD(P)H quinone oxidoreductase
BW16_19750	ENOG4105FBA	Phospholipase Carboxylesterase
BW16_19755	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
BW16_19760	ENOG4105E90	ABC transporter
BW16_19765	ENOG4108IJ8	ABC transporter
BW16_19770	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BW16_19775	ENOG4108UUM	single-stranded DNA-binding protein
BW16_19780	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
BW16_19785	ENOG4105C3G	gtp-binding protein
BW16_19790	ENOG4105VDK	protein, conserved in bacteria
BW16_19810	ENOG4108ZDA	Sporulation protein YyaC
BW16_19815	ENOG4105FA0	parb-like partition protein
BW16_19820	ENOG4107QJE	Chromosome Partitioning Protein
BW16_19835	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BW16_19840	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BW16_19845	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BW16_19855	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BW16_19860	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
